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135
21e8b417-234a-4f0e-bf20-5d6c797e28fd
Gray hepatization of lungs is seen on the day -
1
3-Feb
5-Mar
7-May
3d
single
All 4 phases may be seen in different parts of the same lung Congestion (1-2 days) Red hepatization (2nd-4th day) Gray hepatization (5th-8th day) Resolution (8th-9th day)
Pathology
null
0757d89a-114e-4bfc-b937-fe2ec71101c2
All the following are at-risk groups meriting Hepatitis B vaccination in low endemic areas EXCEPT-
Patients on chronic hemodialysis
Diabetics on insulin
Medical/nursing personnel
Patients with chronic liver disease
1b
multi
high prevalence of hepatitis B in ceain locality and dialysis units, together with the recent discovery of occult hepatitis B infection, vaccination of non-immune clinical staff and renal patients preferably before the development of advanced renal failure appears paicularly impoant in the control of HBV Ref Davidson e...
Medicine
G.I.T
e58359d0-0674-41fb-a596-7b551c4ef2b7
An extracted tooth is discarded in which bag?
Yellow
Red
Black
Blue
0a
single
null
Dental
null
29c31b8d-d79b-4a83-a460-08017f494344
All true about armoured endotracheal tube except
These are tube with metal wire coil embedded in the wall of the tube shaft.
It has radiopaque line like normal ETT
It is bend resistant
It has slightly thicker outer wall as compared to normal ETT
1b
multi
Just likestandard ET tubes,armored or reinforced tubes have the typical left-facing bevel tip and Murphy eye. Their distinctive feature is ametal wire coilembedded in the wall of the tube shaft. The fact that these tubes contain a metal wire coil means there is no need for a radio-opaque line. Useful in head and neck s...
Anaesthesia
Airway
c7086a43-6847-483b-9e47-17d46f6f9540
The Vitamin A supplement administered in “Prevention of nutritional blindness in children programme” contains
25,000 IU/ml
3 lakh IU/ml
1 lakh IU/ml
5 lakh IU/ml
2c
single
Vitamin A solution contains 1 lac IU per ml solution Vitamin A is given in NIS of India till 5 years age (Recent guidelines) – At 9 months age: 1 lac IU (1 ml) – Every 6 months, till 5 years age: 2 lac IU (2 ml) each – Total dose given: 17 lac IU (9 doses).
Social & Preventive Medicine
null
3155eccf-fdc9-4538-88ea-81407700fb48
Immunostimulant used for the treatment of malignant Melanoma Norma is
Levamisol
BCG
Aldesleukin
Methotrexate
2c
single
Ref-Katzung 10/e p906 It is a recombinant IL-2 used for the treatment of renal cell carcinoma and malignant melanoma
Anatomy
Other topics and Adverse effects
4493ca04-c097-4081-a5ab-25ebc201c58b
BCG is used for:
Treatment of tuberculosis
Treatment of superficial bladder cancer
Treatment of anthrax
All of the above
1b
multi
(Ref: Goodman & Gliman 11/e p1422) BCG is used for immunization against TB. It is also used for the treatment of superficial bladder cancers. It is directly instilled in the urinary bladder for this purpose.
Pharmacology
Other topics and Adverse effects
4e842c4f-baca-4846-8904-ce8459dd8cab
What could be the possible diagnosis as per the given X-ray?
Osgood schattler disease
Pellegrinl Stieda lesion
SLAP tear
Segond Fracture
0a
single
Osgood-Schlatter disease(OSD)is a chronic fatigue injury due to repeated microtrauma at the patellar ligament inseion onto the tibial tuberosity, usually affecting boys between ages 10-15 years. Osgood-Schlatter disease is seen in active adolescents, especially those who jump and kick, which is why it is seen more freq...
Radiology
Musculoskeletal Radiology
8d881f5e-5240-453f-b97b-eafce93ec13c
One of the following features can be used to define contracted pelvis
Transverse diameter of inlet is 10 cm
AP diameter of inlet is 12 cm
Platypelloid pelvis
Gynaecoid pelvis
0a
single
Minimal/Critical diameters of the Pelvis: If any of the following diameter is less than critical diameter, Pelvis is said to be contracted
Gynaecology & Obstetrics
null
27eeb364-6735-4378-9ef9-9e98820d76da
True regarding predisposing factors for penile carcinoma are all except: March 2012, March 2013 (e)
Paget's disease
Genital was
Circumcision
Leucoplakia
2c
multi
Ans: C i.e. Circumcision Premalignant conditions for carcinoma penis Leucoplakia of the glans (similar to the condition seen n the tongue), longstanding genital was (which may rarely be the site of malignant change) & Paget's disease of the penis are definite precarcinomatous states Circumcision soon after bih confers ...
Surgery
null
147d10f7-f702-460f-a7b7-40edd97ee510
A neonate presenting with ascites is diagnosed having urinary ascites. What is the most common cause:
Bilateral PUJ obstruction
Infant polycystic kidney disease
Posterior urethral valve
Meatal stenosis
2c
single
null
Surgery
null
1459020c-a7a5-4a34-b80f-38b27075e293
A 30 year old farmer presents with the features of high fever, painful inguinal lymphadenopathy, vomiting and diarrhoea with hypotension. Which of the following stain will be helpful in making the diagnosis?
Wayson's stain
Neisser stain
Albes stain
McFadyean's stain
0a
single
Wayson's stain is a basic fuchsin - methylene blue, ethyl alcohol - phenol microscopic staining procedure. It is a modified methylene blue stain used for diagnosing bubonic plague. Giemsa / Wayson stain revels the typical safety- pin apperance of the organism. In Bubonic plague the infected flea bite is usually on the ...
Microbiology
null
093cc84c-2c76-4051-8eb6-d2cd335281ce
A person is said to be mentally retarded when IQ is-
< 100
<90
<80
<70
3d
multi
Ans. is 'd' i.e., < 70 o Normal IQ- 90-109;o Borderline IQ- 70-89;o Mild mental retardation IQ- 50-69;o Moderate mental retardation IQ- 35-49;o Severe MR IQ- 20-34;o Profound MR IQ- 0-19.
Psychiatry
Intellectual disability, communication, autism, and ADHD
5b19aa2f-4c82-4552-8a79-6d9933839d11
Differential diagnosis for pancytopenia with cellular bone marrow include the following except -
Megaloblastic anemia
Myelodysplasia
Paroxysmal Nocturnal Hemoglobinuria
Congenital dyserythropoietic anemia
0a
multi
In megaloblastic anemia , RBCs WBCs & platelets decreases (pancytopenia) & the cellularity of the bone marrow increases from moderate to hypercellular.Ceain morphologic features are common to all forms of megaloblastic anemia. The bone marrow is markedly hyper- cellular and contains numerous megaloblastic erythroid pro...
Pathology
Haematology
26b1a380-7d06-49c1-b6b7-0c081a074f46
Best for systemic aspergillosus infection ?
Ketoconazole
Itraconazole
Fluconazole
Flucytocine
1b
single
Ans is 'b' i.e., ltraconazole o First choice drug for aspergillosis Voriconazole/Amphotericin B o Second choice drug for aspergillosis --> ltraconazole
Pharmacology
null
c08f922f-a013-46b0-8717-47184080821c
The principal vector of dengue virus-
Anopheles culicifacies
Aedes aegypti
Anopheles stephensi
Culex molestus
1b
multi
The principal vector of dengue is the mosquito Aedes aegypti, which breeds in standing water; collections of water in containers, water based air coolers & tyre drumps are a god environment for the vector in large cities. Reference: Harrison20th edition pg 879
Medicine
Infection
fb6a892d-a588-4245-8ea3-109c3644b8ac
Which of the following is not a culture bound syndrome
Amok
Latah
Dhat
Von-Gogh
3d
single
Ans is 'd' i.e. Von-Gogh * Dramatic self mutilation occurring in schizophrenia has also been called Von-Gogh syndrome.Culture-bound syndrome (folk illness)* It is a combination of psychiatric and somatic symptoms that are considered to be a recognizable disease only within a specific society or culture. There is no obj...
Psychiatry
Miscellaneous
16647cc5-923b-4acc-8261-123f1b3cc121
In Epidemic dropsy disease, toxin is:-
Ergot toxin
Sanguinarine
BOAA
Alkaloids
1b
single
Epidemic dropsy It is caused by contamination of mustard oil with 'Argemone oil'. Sanguinarine is the alkaloid toxin contained in argemone oil. The symptoms of epidemic dropsy consist of sudden,non-inflammatory, bilateral swelling of legs, often associated with diarrhoea, dyspnea, cardiac failure & death may follow. So...
Social & Preventive Medicine
Miscellaneous
f7851b1b-d2dd-4722-b134-2cf6a278131a
A female presented with long standing nasal obstruction. She also complaints about comments from her friends telling about foul smell coming from her nose which she could not recognise. On evaluation, atrophic rhinitis is diagnosed. What can be the etiology in this patient to develop secondary atrophic rhinitis?
Chronic sinusitis
Nasal trauma
Oropharyngeal cancer
Strong hereditary factors
0a
single
Specific infections like syphilis, lupus, leprosy, and rhinoscleroma may cause destruction of the nasal structures leading to atrophic changes. Atrophic rhinitis can also result from long-standing purulent sinusitis, radiotherapy to nose or excessive surgical removal of turbinates. Extreme detion of nasal septum may be...
ENT
null
d12e78d3-6249-49de-8d70-680af7a2e738
A 42-year old female presents with the complaint of bleeding gums for the past 20 days. Intra-oral examination shows thickened and friable gums. Also, she has hepatosplenomegaly with generalized non tender lymphadenopathy. The blood  count reveals: Hemoglobin 11.4 g/dl, Platelet count 90,000/mm3, WBC count 4600/mm3. Th...
Acute lymphoblastic leukemia
Acute megakaryocytic leukemia
Acute promyelocytic leukemia
Acute monocytic leukemia
3d
single
Patient has an “aleukemic” leukemia in which leukemic blasts fill the marrow, but the peripheral blood count of leukocytes is not high. The staining of the blasts suggests the presence of monoblasts (peroxidase negative and nonspecific esterase positive). So, the likely diagnosis for her is M5 leukemia, which is characte...
Pathology
null
a744c6bb-c72d-49e0-a0d4-e1a49e62e7cf
Osteomeatal complex(OMC) connects:
Nasal cavity with maxillary sinus
Nasal cavity with sphenoid sinus
The two nasal cavities
Ethmoidal sinus with ethmoidal bulla
0a
single
Osteomeatal complex lies in the middle meatus. It is final common drainage pathway for the maxillary,frontal,and anterior ethmoid sinuses into the nasal cavity. Ref.Scott Brown 7/e,Vol 2 p 1345
ENT
Nose and paranasal sinuses
f6cdf47a-5e9c-42ac-9abb-e8aa3d128bcd
The clinical consequences of hypokalemia in skeletal muscle include muscle weakness and cramps. What is the level of Serum Potassium at which Paralysis Is a possible complication of hypokalemia?
Serum Potassium at 2.0 mEq/L
Serum Potassium at 2.5 mEq/L
Serum Potassium at 3.0 mEq/L
Serum Potassium at 3.5 mEq/L
1b
single
Paralysis occurs when potassium levels are <2.5 mEq/L. It usually stas in legs and moves to arms
Pediatrics
Disorders of Sodium and Potassium
088c9d93-1b8e-48e9-978b-f9dd690b1eac
A subpoena is a kind of -
Decomposed body tissue
Designation
Document
Court tribunal
2c
single
Summon (subpoena) is a legal document compelling attendance of a witness in a court of law.
Forensic Medicine
null
a06f0291-c833-48a9-b717-966658d9c6b1
OPV bivalent vaccine contains -
Polio virus 1 & 3
Polio virus 1 & 2
Polio virus 2 & 3
None
0a
multi
<p>OPV/ Sabin vaccine Live attenuated . Contains type 1,2 and 3 viruses grown in primary monkey kidney/human diploid cell culture. Administration:- WHO programme on immunisation (EPI) and the national immunisation program in India recommend a primary course of 3 doses of vaccine with 1 month interval commencing at 6 we...
Social & Preventive Medicine
Communicable diseases
1dfebf58-56d7-48e7-ab5c-0d9c699e2e01
Which of the following is the classical CSF finding seen in TBM?
Increased protein, decreased sugar, increased lymphocytes
Increased protein, sugar and lymphocytes
Decreased protein, increased sugar and lymphocytes
Increased sugar, protein and neutrophils
0a
single
Harrison's textbook of internal medicine 17the edition *CSF revealed a high leucocyte count (up to 1000/microL),usually with predominance of lymphocyte s ,but sometimes with predominance of neutrophils in early stage ,protein count of 1-8g/L and low glucose concentration .
Medicine
C.N.S
bd4ef677-9e38-4540-9533-c9775ed7e3c2
Winter bottom's sign in sleeping sickness refers to-
Unilateral conjunctivitis
Posterior cervical lymphadenopathy
Narcolepsy
Transient erythema
1b
single
Sleeping sickness Fever Loss of nocturnal sleep Headache Feeling of oppression Pruritis and maculopapular rashes Weight loss Arthralgia Hepatosplenomegaly Lymphadenopathy, particularly of the posterior triangle of the neck → Winter bottom's sign
Microbiology
null
1c3b18a3-b1a6-438b-a752-30411f8deb2a
Clostridium difficile causes -
Pseudomembranous colitis
Nosocomical diarrhea
Gas gangrene
Food poisoning
0a
single
Ans. is 'a' i.e., Pseudomembranous colitis & 'b' i.e., Nosocomical diarrhea * Cl difficle causes Clostridium difficle - associated diseases (CDAD).* CDAD is the most commonly diagnosed diarrheal illness acquired in the hospital.* C. difficle is acquired exogenously, most frequently in the hospital.* C. difficle is the ...
Microbiology
Bacteria
8fc055da-d19c-4db3-90ba-93c2cf84d8a3
The muscle of hand that contains a sesamoid bone is
Flexor pollicis brevis
Flexor pollicis longus
Opponens pollicis
Adductor pollicis
3d
single
The tendon of inseion of adductor pollicis on the medial side of base of proximal phalanx of thumb contains a sesamoid bone.Reference: Textbook of anatomy, Upper limb, and thorax, Vishram Singh, 2nd edition, page no.144
Anatomy
Upper limb
3aea82bd-2bfa-40a9-8368-0e439d039931
A 70-year-old man has smoked for years despite a chronic productive cough. One day, he notices blood in his sputum and goes to see his physician. A chest x-ray reveals a mass in the left lung, which is biopsied during a fiberoptic bronchoscopy. Assuming that this patient's cancer is etiologically related to his smoking...
Adenocarcinoma or bronchioloalveolar carcinoma
Adenocarcinoma or small cell carcinoma
Bronchioloalveolar carcinoma or small cell carcinoma
Small cell carcinoma or squamous cell carcinoma
3d
multi
Smoking does not increase the risk of all types of lung cancers to the same degree. Oat (small) cell carcinoma has a very strong association with smoking, with only 1% of cases occurring in nonsmokers. Squamous cell carcinoma is also strongly associated with smoking, because smoking predisposes for squamous metaplasia,...
Pathology
null
c4b91955-4ee9-43e6-8939-7fb19d7d16dd
Which of the following exocrine glandular ducts are not obstructed in cystic fibrosis:
Pancreas
Lung
Sweat gland
All of above
2c
multi
Answer C. Sweat glandMost CF patients have 3 distinct abnormal characteristics:The ducts of the mucus-secreting glands are obstructed due to an increase in viscosity of these secretions leading to glandular dilatation and destruction.CF patients are prone to chronic bacterial colonization and infections.The sweat gland...
Anatomy
null
4d1c8693-4972-45f2-a920-cb9bbddb972f
Long connective tissue papillae and keratinized epithelia are a feature of these parts of oral mucosa
gingiva and alveolar mucosa
hard palate and gingiva
buccal and alveolar mucosa
hard and soft palate
1b
single
null
Dental
null
a3a464ef-b242-4bc1-9e61-8f92b1ce765a
Distal interphalangeal joints are involved in all except ?
Psoriatic ahritis
Rheumatoid ahritis
Reactive ahritis
Osteoahritis
1b
multi
Ans. is 'b' i.e., Rheumatoid ahritis
Surgery
null
511ee778-4f6c-494c-b702-1b2c80b52bcd
Pearls index
Per 10 woman years
Per 100 woman years
Per 1000 woman years
Per 10,000 woman years
1b
single
Pearl index is defined as the number of failures per 100 woman years of exposure (HWY) Failure rate per Hundred Women Years = Total accidental pregnancies X 1200/ Total months of exposure Reference : Park&;s textbook of preventive and social medicine, 23rd edition, Page no: 510
Social & Preventive Medicine
Demography and family planning
0e6b6057-7402-42b3-80d8-45e87a23bf77
Occult thyroid malignancy with nodal metastasis is seen in -
Medullary carcinoma
Follicular ca
Papillary ca
Anaplastic ca
2c
single
A small percentage of cancers present with enlarged lymph nodes in the jugular chain or pulmonary metastases with no palpable abnormality of the thyroid. The primary tumor may be no more than a few millimetres in size and is termed occult. Such primary foci of papillary carcinoma may also be discovered in thyroid tissu...
Surgery
null
3bab6fb6-73f8-4234-a13c-c5dd06b36e6f
In which type of nerve fibers is conduction blocked maximally by pressure
A alpha
A beta
A gamma
C
0a
multi
null
Physiology
null
0ba7c146-91c7-492b-a7ce-8ace350d23ec
In stab wounds, Langer's lines determine: NEET 14
Direction
Gaping
Shelving
Healing
3d
single
Ans. Healing
Forensic Medicine
null
1cae03a9-20b4-401c-9bd7-dc3714181799
Which cranial nerve is affected the earliest in acoustic neuroma?
CN 5
CN 7
CN 10
CN 9
0a
single
The pear shapped tumour from the cranial nerve VIII continue to enlarge and compress the trigeminal nerve. Cranial nerve 5 is the earliest nerve to be involved in Acoustic neuroma. The tumor is almost always arises from the Schwann cells of the vestibular, but rarely from the cochlear division of VIIIth nerve within th...
ENT
null
07c5bf22-1ebb-4b91-a2fb-9c9830767761
Which of the following decreases affinity of oxygen with hemoglobin?
Decreased H+ ions
2,3 BPG
Decrease in temperature
Decreased sorbitol
1b
single
Decrease affinity of oxygen with hemoglobin-Oxygen hemoglobin curve shift to right -increaseddelivery of oxygen to the tissue Increase affinity of oxygen with hemoglobin -Oxygen hemoglobin curve shift to left- Increased delivery of oxygen to the HEMOGLOBIN in lungs Factors increase hydrogen ions (acidosis ) Increase CO...
Biochemistry
JIPMER 2018
c08c3f20-0027-4c7b-99c2-4a8a4bacad6b
Non-septate hyphae with a tendency to branch at 90 degree angle is characteristic of:
Mucormycosis
Aspergillosis
Cryptococcus neoformans
Coccidioides immitis
0a
single
The organisms appear as large, nonseptate hyphae with branching at obtuse angles. Round or ovoid sporangia are also frequently seen in the tissue section. Histopathologically, mucormycosis should be differentiated from aspergillosis in which the former has an acute angulating branched hyphae of smaller width and latter...
Pathology
null
3106dc30-60fc-41b5-8fa9-5ddcbfab28d8
Meniscal tears usually result from which of the following circumstances?
Hyperextension
Flexion and rotation
Simple hyperflexion
Compression
1b
multi
Most meniscal tears are produced by flexion and rapid rotation. A classic example ("football knee") involves a player who is hit while running. The knee, supporting all the player's weight, usually is slightly flexed, and the foot is anchored to the ground by cleats. Impact from an opposing player usually causes rotati...
Surgery
Orthopedics
6eb8fff2-6fd0-45d6-899c-fb8ce9c03aaf
Minimum reabsorption through renal tubule, among the following
Glucose
HCO3
Urea
Uric acid
2c
single
Urea is a toxic waste product and it reabsorbed in minimal level.Ref: Ganong&;s Review of Medical Physiology; 24th edition; page no: 678
Physiology
Renal physiology
0a447dda-60da-4c72-9dd8-9ed8099de88e
In formocresol, ratio of formalin to cresol:
3:02
2:03
1:02
2:01
2c
single
Formocresol is a solution of 19% formaldehyde, 35% cresol in a vehicle of 15% glycerine and water. To prepare a 1:5 concentration of this formula, first thoroughly mix 3 parts of glycerin with 1 part of distilled waler, then add 4 parts of this preparation to 1 part Buckley’s formocresol, and thoroughly mix again. Key ...
Dental
null
aa9b2408-301c-4484-9d60-ae41647dfc51
V. cholera is able to stay in GIT because of ?
Acid resistance
Bile resistance
Motility
Binds to specific receptors
2c
single
Ans. is 'c' i.e., Motility
Microbiology
null
33dcfe1c-a035-4caa-a9af-5df678410247
Apex of maxillary sinus points towards
Zygomatic bone
Nasal Cavity
Orbital surface
None of the above
0a
multi
null
Dental
null
90a3c304-0623-4d39-9b36-dba90df0c843
Udai Pareek scale does not include
Education
Family members
House
Income
3d
single
null
Social & Preventive Medicine
null
65679a84-a18f-462a-86c9-9a0c7b9eec0b
The caudate lobe of liver corresponds to which segment of Counaud's classification
Segment I
Segment II
Segment III
Segment IV
0a
single
Caudate lobe is segment I Quadrate lobe is segment IVa The caudate lobe (segment I) is the dorsal poion of the liver and embraces the IVC. It lies posterior to the left poal triad inferiorly and left and middle hepatic vein superiorly. Caudate lobe is unique in sense that it receives blood supply from both the right & ...
Anatomy
G.I.T
aecf0f24-18f5-4c40-b9f5-d39e7906a4b0
Which of the following can be found in ocular muscles?
Trichinella
Ascaris
Enterobius
None
0a
multi
Trichinella spiralis → It is a parasite of pig. Man is an incidental host. → Infective form is encysted 1st stage larva which is transmitted by eating uncooked pork. → Larva penetrates intestine and migrates to muscles where it undergoes encystation. → Most commonly involved muscles are extraocular muscles followed by ...
Microbiology
null
10fcf69a-608c-4078-9366-bd836ec901f4
Continuous cell culture of bacteria
U tube
Craige tube
Chemostat device
Agar dilution method
2c
single
Ans. is 'c' i.e., Chemostat device Bacterial cultures can be maintained in a state of exponentional growth over long periods of time using a system of continuous culture. Continuous culture, in a device called chemostat, can be used to maintain a bacterial population at a constant density, a situation that is, in many ...
Microbiology
null
8f70097e-fa15-4f35-85bb-da68c9c83024
Which is the most common tumor associated with superior vena cava syndrome?
Lung cancer
Lymphoma
Metastasis
Thyroid cancer
0a
single
The superior vena cava syndrome usually is caused by neoplasms that compress or invade the superior vena cava, such as bronchogenic carcinoma or mediastinal lymphoma. -produces a characteristic clinical complex consisting of marked dilation of the veins of the head, neck, and arms associated with cyanosis. -Pulmonary v...
Pathology
Lung Tumor
b60449dd-89b3-4f99-8ecc-a601fd9f45c2
All of the following enzymes are active within a cell except
Trypsin
Futnerase
Hexokinase
Alcohol dehydrogenase
2c
multi
Red Blood Cell Enzymopathies Hexokinase (HK), the red cell enzyme with the lowest activity in the glycolytic pathway, catalyzes the initial step in the utilization of glucose and thus is required for both glycolysis and the pentose shunt and produces glucose 6-phosphate. Ref Robbins 9/e pg 407
Physiology
General physiology
aa919d78-e83c-48d9-9514-56bdb7acb05b
Pars flaccida of the tympanic membrane is also called as
Reissner's membrane
Shrapnel's membrane
Basilar membrane
Secondary tympanic membrane
1b
multi
Situated above the lateral process of malleus between the notch of Rivinius and the anterior and posterior malleolar fold. Reference: Dhingra 6th edition
ENT
Ear
600057d1-acc5-4004-8a9a-64a218df1850
DNA analysis of chorionic villus/amniocentesis is not likely to detect:
Tay-Sach's disease
Hemophilia A
Sickle cell disease
Duchenne muscular dystrophy
0a
single
Ans. is a, i.e. Tay-Sachs diseaseRef. JB Sharma TB of Obs pg 161; Williams Obs 25/e, p 296Ref Operative Obs and Gynae by Randhir Puri, Narendra Malhotra 1/e, p 261, 262; Obs. and Gynae Beckmann 5/e, p 45In chorionic villous biopsy, trophoblastic tissue is obtained from the chorionic villi, followed by biochemical or mo...
Gynaecology & Obstetrics
Diagnosis in Obstetrics
113a2d25-3955-4c22-af7e-c5f7a06cbaa5
A 37-year-old man is admitted to the hospital with a productive cough, fever, and night sweats. An X-ray film of the chest shows an ill-defined area of consolidation at the periphery of the right middle lobe and mediastinal lymphadenopathy. Sputum culture grows acid-fast bacilli. Lymph node biopsy in this patient would...
Caseating granulomas
Follicular hyperplasia
Nodular amyloidosis
Noncaseating granulomas
0a
single
Tuberculosis is a chronic, communicable disease in which the lungs are the prime target. The disease is caused principally by Mycobacterium tuberculosis hominis (Koch bacillus), but infection with other species occurs, notably M. tuberculosis bovis (bovine tuberculosis). Primary tuberculosis consists of lesions in the ...
Pathology
Infectious Disease
7be27a40-95cf-4a39-93e8-c2d4859f954c
Zidovudine toxicity is increased by all except
Azithromycin
Probencid
Cisplatin
Cyclophosphamide
0a
multi
null
Medicine
null
ae1daee7-049a-4740-b7d2-4bc82b4aa1ed
Most common abdominal mass in children:
Hydronephrosis
Wilms' tumor
Neuroblastoma
Rhabdomyosarcoma
2c
single
c. Neuroblastoma(Ref: Nelson's 20/e p 2464-2466, Ghai 8/e 617-618)Neuroblastoma is the most common extracranial solid tumor in childrenLocalized Neuroblastoma can manifest as an asymptomatic mass or can cause symptoms because of the mass itself, including spinal cord compression, bowel obstruction & superior vena cava ...
Pediatrics
Childhood Tumors
32dbef97-470a-4371-9d8d-916aba690207
Healthworker-hand washing
Cleaning hands with spirit before and after examination of each patient
Visible blood stain on hand is washed with soap and water
Use of soap an Dettol only for hand washing before surgery
Hand rub cannot be used in place of hand washing
0a
single
(A) Cleaning hands with spirit before and after examiation of each patient > Introduction of easily accessible dispensers with an alcohol-based waterless handwashing antiseptic led to significantly higher handwashing rates among health care workers.
Social & Preventive Medicine
Miscellaneous
2c4dffc8-a305-4e0d-997e-6e0ed10fe6f4
All of the following statement about Renal Calculi are true, Except:
Cystine stones form in acidic urine
Struvite stones form in alkaline urine
Oxalate stones are radiopaque
Uric acid stones are resistant to ESWL
3d
multi
Answer is D (Uric acid stones are resistant to ESWL): Uric acid stones are not resistant to ESWL. Uric acid stones are infact most responsive to Lithotripsy along with calcium oxalate dehydrate stones.
Medicine
null
d49fcebe-a343-4abc-a215-cff9e95e40ca
Shenton line is seen in X-ray of
Knee
Shoulder
Elbow
Hip
3d
single
Shenton line is an imaginary curved line drawn along the inferior border of the superior pubic ramus (superior border of the obturator foramen) and along the inferomedial border of the neck of femur. Ref essentials of ohopaedic maheshwari and mhaskar 6/e p150
Physiology
All India exam
af0935dc-ac1c-4dec-82f4-bfc6ef354761
Normal size but non functioning uterus is usually associated with :
Stenosis of the external os
Uterine synechiae
Paial agenesis of the vagina
Complete absence of vagina
1b
multi
A hysterosalpingogram or preferably a diagnostic hysteroscopy helps to establish the diagnosis of Asherman syndrome, first described in 1948. Operative hysteroscopy to lyse the synechiae, followed by cyclic hormonal therapy with high doses of conjugated oestrogens of 2.5-5.0 mg/day for 3-6 months, results in the restor...
Gynaecology & Obstetrics
Sexuality and intersexuality
a696d3a6-6b64-45e1-82e3-730016498ae3
All are used in treating spasmodic dysmenorrhea except:
Bromocriptine
Ibuprofen
Mefenamic acid
Norethisterone and ethinyl estradiol
0a
multi
Spasmodic dysmenorrhoea is another name for primary dysnenorrhoea. (i.e. no pelvic pathology is responsible for pain) Characteristics of spasmodic dysmenorrhoea • Seen in adolescent girls • Pain appears within 2 years of menarche • Family history may be present • Pain is spasmodic nature. It is located in lower abdomen...
Gynaecology & Obstetrics
null
a5a31bbf-a1e6-4d80-b54e-e73e26ba4c8a
Which of the following is not a characteristic of right sided failure -
Pulmonary oedema
Ascites
Oliguria
Dependent
0a
single
Ans. is 'a' i.e., Pulmonary edema Pulmonary edema is due to Lt sided hea failure that results in increased back pressure in pulmonary circulation. Signs of CHF in infants Left sided failure Tachypnea Tachycardia Cough Wheezing Rales in chest Hoarse Cry Failure of either side Cardiac enlargement Gallop rhythm (S3) Perip...
Pediatrics
null
3d81e630-7f3d-4861-94d4-5e0e2723c73d
An 8 years old boy from Bihar presents with a 6 months history of an ill defined, hypopigmented slightly atrophic macule on the face. The most likely diagnosis is:
Pityriasis alba
Indeterminate leprosy
Vitiligo
Calcium deficiency
1b
single
Indeterminate leprosy is characterized by: a. Solitary, hypo pigmentary patch over face in a child b. Scaling absent c. Atrophy present d. Patient from endemic area eg Bihar, Jharkhand, Chhattisgarh Differential diagnosis Pityriasis alba Intermediate leprosy Solitary, hypo pigmentary patch over face in a child + + Scal...
Dental
Mycobacterial Infections
4cf89529-3e94-4f0f-a383-c68f9b66908f
A 25yr old male with thyroid swelling Biopsy shows intense lymphocytic infiltration along with huhle cell change TSH increased
Hashimoto's thyroiditis
Grave's disease
follicular carcinoma
Medullary carcinoma thyroid
0a
single
Hashimoto&;s Thyroiditis Biopsy features of lymphocytic infiltrate along with huhle cell change in thyroid swelling is diagnostic of hashimoto&;s thyroiditis ref : robbins 10th ed
Pathology
All India exam
ac5e62fd-723e-465b-ba02-cc84adfa210a
The lineage specific marker for B cells is
CD 19
CD 20
CD 21
CD 22
0a
single
Lineage specific B cell marker is CD 19. However on IHC the best marker is CD 20. CD 21 is the receptor for EBV
Unknown
null
8563e2f8-eb30-48b9-b00c-5423912e8e70
Reversible loss of polarity with abnormality in size and shape of cells is known as -
Metaplasia
Dysplasia
Hyperplasia
Anaplasia
1b
single
Metaplasia Metaplasia is an adaptive change in which one adult (mature) cell type is replaced by another adult (mature) cell. In this differentiation is not lost, rather it changes from one lineage to another, i.e. stems cell differentiates along a new pathway. But, the resulting cells are fully mature and differentiat...
Pathology
null
d793e3b6-a41e-4ece-9a0a-1b9d11f47279
All of the following statements are true regarding sumatriptan except
It has 99% oral bioavailability
It is contraindicated in coronary aery disease
It constricts cranial vessels
It is selective 5-HT 1B/ID receptor agonist
0a
multi
TRIPTANS Sumatriptan is the drug of choice for aboing acute attack of migraine. It acts as a selective agonist at 5 HT1B/1D receptors. This result in constriction of cranial vessels. It also suppresses the vomiting of migraine. It is a sho acting drug and has low oral bioavailability. Frovatriptan is the longest acting...
Pharmacology
Histamine, 5-HT and PGs
ad067894-8a87-4b25-b8e2-19dff2d96652
The most common form of dissociative hysteria is:
Fugue
Amnesia
Multiple personality
Somnambulism
1b
single
Dissociative amnesia is the most common type of dissociative disorder.
Psychiatry
Neurotic, Stress Related and Somatoform Disorders
d69e0e55-7d2d-4ce6-bad4-6a8ebbb3cb42
Which is a large granular lymphocyte?
NK cell
B-lymphocyte
T-lymphocyte
Macrophage
0a
single
Ans. (a) NK cell(Ref: Wintrobe's clinical hematology - 12th ed, pg 300; Robbins 9th/pg 192; 8th/pg 188)Most lymphocytes in blood are small (<=10mm), while some are large, known as large granular lymphocytes (LGL), as they contain azurophilic granules in their cytoplasm.These cells are LGL type of natural killer (NK) ce...
Pathology
Immunity
ae30ac4b-f517-42a9-9685-8dec94394f57
Schaumann bodies are seen in -
Sarcoidosis
Chronic bronchitis
Asthma
Syphilis
0a
single
question repeated In pathology, Schaumann bodies are calcium and protein inclusions inside of Langhans giant cells as pa of a granuloma. Many conditions can cause Schaumann bodies, including: Sarcoidosis, Hypersensitivity pneumonitis, and Berylliosis. uncommonly, Crohn's disease and tuberculosis.
Pathology
Respiratory system
b32e482c-6a0b-4a5f-b22f-939969a628df
Which of the following drugs is associated with untoward side effect of renal tubular damage-
Cisplatin
Steptozotocin
Methysergide
Cyclophosphamide
0a
multi
Some nephrotoxic agents which cause tubular necrosis. o Aminoglycosides o Colistin o Methoxyfluranes o Sulfonamides o Amphotericin B o Cyclosporine o Polymyxin o Tetracyclines o Cephaloridine o Intravenous immune globulin o Radioiodinated contrast o Acetaminophenmedium o Cisplatin REF : katzung pharmacology : 14th ed
Pharmacology
All India exam
623b2f94-0277-4ccd-9cfd-68bd8a6085fa
Which of the following nucleus in brain is common to IX, X & XI cranial nerves?
Nucleus solitarius
Nucleus ambiguus
Dentate nucleus
Red nucleus
1b
single
Nucleus ambiguus consists of large motor neurons and is situated deep within the reticular formation. The emerging nerve fibers join the glossopharyngeal, vagus and cranial pa of the accessory nerve and are distributed to voluntary skeletal muscle. The neurons in the nucleus ambiguus innervate the ipsilateral laryngeal...
Anatomy
null
505db5f5-7e22-425c-af33-62fcbb1ebdaf
Digoxin toxicity it can be increased by all except
Renal impairment
Hyperkalemia
Hypetmagmesimia
Hypercalcemia
1b
multi
Hyperkalemia is the usual electrolyte abnormality precipitated by digoxin toxicity, primarily in the acute setting. Hyperkalemia may be associated with acute renal failure that subsequently precipitatesdigoxin toxicity. Chronic digoxin toxicity does not usually causehyperkalemia. Refer katzung 11e p216
Pharmacology
Cardiovascular system
61fcf97e-b743-43bf-a4ad-86dcc8985e74
A double apical impulse is seen in
AS & AR
TR&TS
MI
HOCM
3d
single
(D) HOCM# Physical findings of HCM are associated with the dynamic outflow obstruction that is often present with this disease.> Upon auscultation, the heart murmur will sound similar to the murmur of aortic stenosis.> However, a murmur due to HCM will increase in intensity with any maneuver that decreases the volume o...
Medicine
Miscellaneous
0cb2f8bc-a093-436c-9868-10d08fbcfd26
Safest method of contraception in sickle cell anaemia:
Oral 'Pill'
IUCD
Barrier method
Progestin only pill or implant
2c
single
null
Gynaecology & Obstetrics
null
60372da3-86a2-4148-aadd-dadd149a41dc
Which of the following agent is used in day care surgery?
Propofol
Thiopentone
Ketamine
Diazepam
0a
single
Ans. a. Propofol (Ref: Miller's Anesthesia 8/e p726; Lee 13/e p158-160; Morgan 3/e 173, 884)Propofol is used in day care surgery.'Any induction agents used in day-case anesthesia should ensure a smooth induction, good immediate recovery and a rapid return to street fitness. Propofol is now used widely as the primary in...
Anaesthesia
Miscellaneous General Anesthesia
131553a7-e03a-49c4-ac0e-c467fbe039a2
Which of the following can prevent neural tube defects in pregnancy?
Iron
Vit B12
Folic acid
Zinc
2c
single
Ans: c (Folic acid) Ref: Dutta, 6th ed, p. 104, 409Folic acid is supplemented in the first trimester to prevent neural tube defects.Folic acid supplementation:1. Normal pregnancy -0.5 mg in first trimester2. Pregnancy with history of NTD - folic acid 4mg daily, 1 month before conception continued for 12 weeks of pregna...
Gynaecology & Obstetrics
Miscellaneous (Gynae)
dbb6d2a3-741b-43c9-a17e-ba5b2d2ebbcc
Which one of the following hepatic lesions can be diagnosed with high accuracy by using nuclear imaging ?
Hepatocellular Carcinoma
Hepatic Adenoma
Focal Nodular Hyperplasia
Cholangiocarcinoma
2c
single
Ans. is 'c' i.e., Focal nodular hyperplasia Liver parenchyma is primarily made up of two types of cells. i) Hepatocytes -> Perform excretory and synthetic function ii) Kupffer cells -> They have reticuloendothelial function Both these cells can be investigated with 99mTc labelled cells. Two types of radionucleide imagi...
Surgery
null
8d67fe49-250d-42f5-8fc0-4d1b5e9fd530
Flexion, adduction and medial rotation of arm is done by which muscle
Serratus Anterior
Pectoralis major
Pectoralis minor
Subclavius
1b
single
Muscle Action Pectoralis major Adducts and medial rotation of arm Pectoralis minor Stabilizes the scapula Subclavius anchors and depresses the scapula Serratus Anterior protracts the scapula laterally rotates the scapula overhead abduction
Anatomy
Upper limb bones and muscles (proximal region) & Scapular movements
a445135c-63c6-4f7d-aa83-557cce127f02
In a patient with poor glycemic control, hypertriglyceridemia, low HDL, which of the following drug Rx would be best without the risk of myositis as its side effect?
Fibric acid derivatives
Nicotinic acid
Atorvastatin
Simvastatin
1b
single
Ans.B Nicotinic acidLIPID-LOWERING AGENTSDrugEffect on LDLEffect on HDLEffect on triglyceridesSide effects/problemsHMG-CoA reductase Inhibitors(Lovastatin, Simvastatin) pravastatin, Atorvastatin)|||||Expensive, reversible LFT's MyositisNiacin|||||Red, flushed fate, which is by aspirin or long-term useBile acid resins(c...
Unknown
null
0cbc7abd-5ba7-4024-9f13-7c5130b59938
For acute leukaemia the blast cells should be more than ____%-
10
20
30
40
1b
single
null
Medicine
null
01781155-df77-4ccc-ac81-ee350dd1ed2d
Most common cause of primary hyperparathyroidism-
Iatrogenic
Medullary carcinoma thyroid
Parathyroid adenoma
Parathyroid hyperplasia
2c
single
Most common cause of primary hyperparathyroidism is autonomous secretion of parathyroid hormone (PTH) by a parathyroid adenoma. Single adenoma (90%), multiple adenomas(4%), nodular hyperplasia(5%), carcinoma(1%). Reference : page 769 Davidson's Principles and practice of Medicine 22nd edition
Medicine
Endocrinology
c2cd8654-2863-4a55-b919-1a69b6de4940
O2 delivery to tissues depends on all of the following factors, EXCEPT:
Cardiac output
Type of fluid administered
Hemoglobin concentration
Affinity of hemoglobin for O2
1b
multi
The fundamental purpose of the cardiorespiratory system is to deliver O2 and nutrients to cells and to remove CO2 and other metabolic products from them. Proper maintenance of this function depends not only on intact cardiovascular (cardiac output) and respiratory systems but also on an adequate number of red blood cel...
Physiology
null
600c6294-b6d3-42ed-bc10-318e605cd566
Which of the following is commonest primary intraocular tumour in childhood is
Neurofibromatosis
Retinoblastoma
Cavernous haemangioma
Melanotic melanoma
1b
single
(Retinoblastoma): Ref: 280-KH, 358-K, 397-PRETINOBLASTOMA - is the most common primary intraocular malignancy of childhood.* The retinoblastoma may be heritable (40%) or non heritable (60%)* The predisposing gene (RPE1) is at 13q14* Leukocoria (white papillary reflex) is the commonest (60%) presentation* Delation invol...
Ophthalmology
Tumors
66450480-63ad-4594-9a3d-d12fbc0ee8f6
Mechanism of direct transfer of free DNA-
Transformation
Conjugation
Transduction
None
0a
multi
null
Microbiology
null
d1265c62-e16a-4329-b836-138706b8e7c0
Sho stature, secondary to growth hormone deficeincy is associated with -
Normal body propoion
Low bih weight
Normal epiphyseal development
Height age equal to skeletal age
0a
single
Ans. is 'a' i.e., Normal body propoion
Pediatrics
null
36fe2959-43b2-4e8c-8aa6-3c42e2e84ef9
Malignant hyperthermia is caused due to which of the following mechanism?
Increased intracellular Na
Decreased intracellular chlorine
Increased intracellular Ca
Increased serum K
2c
single
Ans. is 'c' i.e., Increased intracellular Ca o The mechanism involves a sudden rise in intracellular calcium due to release of stored calcium in sarcoplasmic reticulum, stimulating contraction, rhabdomyolysis and a hypermetabolic state.o Tachycardia and not bradycardia, is a feature of malignant hyperthermia.MALIGN ANT...
Anaesthesia
Depolarising Neuromuscular Blocking Agents
2b9df3f4-5aeb-4ec2-b560-c75fcbc34fb4
Posterior cardinal vein develops into:
Superior vena cava
Internal jugular vein
External jugular vein
Common iliac vein
3d
single
-Right Posterior cardinal veins contribute to inferior vena cava and common iliac veins. Left anterior and Left posterior cardinal veins regress - Superior vena cava and jugular veins develop from anterior cardinal veins.
Anatomy
Bronchopulmonary Segments, Embryonic veins
18215564-7210-4896-9e86-a81bda3533da
All of the following are seen in polycythemia rubra vera except :
Increased Vit B12 binding capacity (>9000 micromols/dL)
Decreased LAP Score
Leucocytosis
Increased platelets
1b
multi
Answer is B (Decreased LAP Score): Leucocyte alkaline phosphatase is increased in polycythemia vera Characteristic features associated of polycythemia vera Elevated Red Cell Mass/ haematocrit (polycythemia)Q Normal aerial oxygen saturation (a low oxygen saturation would be a physiological stimulus) Plasma erythropoetin...
Medicine
null
f22db951-7560-40a6-ba66-d77b932062fc
A 21 year male with fracture surgical neck humerus presented with regimental badge sign and difficulty in abduction, most likely to be injured
Ulnar nerve injury
Axillary nerve injury
Klumpke's paralysis
Supraclavicular nerve injury
1b
single
null
Orthopaedics
null
2ec531ce-6b21-4ff1-a38d-c3adfb3a3d3c
A 52 year old woman has long standing rheumatoid ahritis (RA) and is being treated with coicosteroids and nonsteroidal anti-inflammatory drugs (NSAIDs). Which of the following cardiac complications may arise in this clinical setting?
Constrictive pericarditis
Dilated cardiomyopathy
Hypersensitivity myocarditis
Restrictive cardiomyopathy
3d
single
Long-standing inflammatory conditions such as rheumatoid ahritis (RA) are associated with deposition of a form of amyloid known as AA (amyloid-associated protein), which may involve kidneys, hea, liver, skeletal muscle, and skin, for example. Amyloid deposition in the myocardium results in decreased compliance and impa...
Medicine
null
4fecaecb-f4fb-4e32-9ff4-438ccc96e14b
Bleeding time is not prolonged in-
Von Willebrand's disease
Christmas disease
Haemophilia
Polycythemia
3d
single
Bleeding time is prolonged in all the platelet disorders like ITP ,TTP and heparin and also prolonged in all types of coagulation disorders and DIC Where is it is normal in vascular diseases like vascular purpuras Reference: textbook of Pathology, 7th edition author Harsha Mohan, page number 317
Pathology
Haematology
04f0fd67-cb33-4baa-9078-c9d8a112cd7f
The "gp 120" in HIV helps in:
Virus attachment
Virus replication
Virus penetration
Virus dissemination
0a
single
Virus attachment
Pathology
null
55184e4d-a1c6-45d0-b694-a5350d311fe3
LASIK (Laser assisted in situ keratomileusis) is useful in treatment of
Myopia
Astigmatism
Hypermetropia
All of the above
3d
multi
Ans. d (All of the above) (Ref. Khurana's ophthalmology, 2nd ed., p 77; Parson's 20th/pg. 76)EXCIMER LASER IN SITU KERATOMILEUSIS (LASER)# Principle:- Myopia is corrected with preservation of Bowman's layer.- A superficial corneal flap (approx. 160 pm) is created with a microkeratome.- The keratome is withdrawn, the fl...
Ophthalmology
Errors of Refraction
1b1ad836-61d6-4668-8f10-8c9844cc8a49
Bias is unlikely to invalidate cohort studies used to assess risk of exposure because -
Data collection is prospective
Large number of subjects is usually included
Exposure is usually determined prior to disease occurrence
Actual relative risk can be determined
2c
multi
null
Social & Preventive Medicine
null
e47e7e6f-5ce1-4ed2-85ee-fab32e92a9a4
The tissues most sensitive to atropine are
The salivary, bronchial and sweat glands
The gastric parietal cells
Smooth muscle and autonomic effectors
The hea
0a
single
Atropine is highly selective for muscarinic receptors. Its potency at nicotinic receptors is much lower, and actions at nonmuscarinic receptors are generally undetectable clinically.The effectiveness of antimuscarinic drugs varies with the tissue and with the source of agonist. In most tissues, antimuscarinic agents bl...
Pharmacology
Autonomic nervous system
00aa7367-b008-4efc-adc3-395cc46f6537
Most common cause of scleritis -
Rheumatoid arthritis
SLE
Sjogren's Syndrome
Behcet's Disease
0a
single
Ans. is 'a' i.e., Rheumato.id arthritis Scleritiso Scleritis is an uncommon disorder which is characterized by cellular infiltration, destruction of collagen and vascular remodelling. Scleritis is usually a bilateral disease and occurs most frequently in women. It is associated with connective tissue diseases in 50% of...
Ophthalmology
Miscellaneous (Sclera)
86847446-1ce1-4199-ad9d-6287a4e99642
Patellar plexus is formed by which nerve
Lateral cutaneous nerve
Intermediate cutaneous nerve
Medial cutaneous nerve
All of the above
3d
multi
Patellar Plexus - It is a plexus of fine nerves situated in front of the patella, the ligamentum patellae and the upper end of the tibia. It is formed by contributions from: (a)The anterior division of the lateral cutaneous nerve, (b) the intermediate cutaneous nerve, (c) the anterior division of the medial cutaneous n...
Anatomy
Lower limb
df5a4187-8358-415b-a0e1-a26978635007
NADPH used in which pathway-
Fatty acid synthesis
Gluconeogenesis
Beta oxidation
Glycogenolysis
0a
single
Ans. is 'a' i.e., Fatty acid synthesisUses of NADPH:* Reductive biosynthesis of lipids# Fatty acid synthesis# Cholesterol synthesis# Steroid hormone synthesis# Fatty acid elongation# Bileacid synthesis
Biochemistry
Carbohydrates
190f648f-75b2-4650-a32b-5574896658e6
Ankylosing spondylitis may be associated with
Atrial fibrillation
Pulmonary stenosis
Aoic incompetence
Mitral stenosis
2c
single
Ref Davidson 23e p1030
Medicine
Immune system
2a54f7c3-f1ec-4503-88c1-7f5c7a957b81
Sec. 377 IPC deals with: AIIMS 09
Rape
Adultery
Sadism
Sodomy
3d
single
Ans. Sodomy
Psychiatry
null