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135
1698551a-4dfb-4345-9971-a6f238866765
Tympanic membrane develops from?
Mesoderm
Endoderm
Ectoderm
All three germ layers
3d
multi
Ans. (d) All three germ layersRef: Longman's medical embryology 12th ed. / 326
Anatomy
Embryology
080e83b3-c4fe-4997-8c92-2f4210eb1d10
Mucoepidermoid carcinoma arises form
Epithelium
Myoepithelium
Acinus
Mucin secreting and epidermal cells
3d
single
Mucoepidermoid carcinomas are composed of variable mixtures of squamous cells, mucus-secreting cells, and intermediate cells. "The low-grade mucoepidermoid carcinoma is composed of largely mucin-secreting cells, whereas in high-grade tumors, the epidermoid cells predominate." They are the most common malignant tumors o...
Surgery
Head and neck
a46bde09-9c2d-46b8-91a4-f5e8cebb6b82
Parasites causing lung infestation are -
H. Nana
Paragonimus westermanii
Taenia saginata
E. granulosus
1b
single
The worm lie in the lung parenchyma and are surrounded by a fibrous capsule formed by host tissue.Inflammatory reaction to the worms and their eggs lead to granuloma formation,cystic dilatation of bronchi,abscesses and pneumonitis.Patient present with cough,chest pain and haemoptysis (refer pgno:131 baveja 3 rd edition...
Microbiology
parasitology
70e567e7-90be-4211-9289-d4af8db8107c
Culex mosquito is a vector for:
Chikungunya fever
Dengue fever
Japanese encephalitis
Malaria
2c
single
ANOPHELES CULEX AEDES MANSONIA Boat shaped Small in clusters Single ; Cigar shaped Star shaped ; in clusters Rest parallel to water surface Rest at an angle to water surface Rest at an angle to water surface Attached to roots of Aquatic plants - Sits by making an angle of 45o with surface - Have straight body & spotted...
Social & Preventive Medicine
VBDs, Arboviral & Viral Infections, Surface Infections
59227e8c-4d0c-4c55-9cb4-f9acc6e701d6
True statement about diphtheria toxin is
Toxin is phage mediated
Toxin is required for local infection
Endotoxaemia causes systemic manifestation
Toxin acts by inhibiting synthesis of capsule
0a
multi
Toxigenicity of the diphtheria bacilli depends on the presence in it of corynephages which acts as the genetic determinant controlling toxin production. The diphtheria toxin acts by inhibiting protein synthesis. Specifically, a fragment B heparin binding and fragment A inhibits polypeptide chain elongation in the prese...
Microbiology
Bacteriology
61eec690-e362-4177-8c6a-6532861dbeb0
All except one are formulas used to calculate fluid replacement in burns patient
Brooke formula
Evan's formula
Parkland regime
Holiday segar formula
3d
multi
Holiday segar formula is not used to calculate fluid replacement in burns patient.
Surgery
null
537070e2-b38a-4e20-84a5-6a0ac089f437
Drug of choice for multidrug resistant staphylococcus aureus is:
Clindamicin
Streptogramins
Vancomycin
Aztreonam
2c
single
Ans: c (Vancomycin)Ref: Harrison 16 ed pg. 821, KDT 6 ed. Pg.732Vancomycin is the drug of choice for MRS A. Quinupristin and dalfopristin are both streptogramin antibiotics that act on MRSA and VRSA. They are used mainly for VRSA.Drugs useful against MRSA:Vancomycin Cotrimoxazole Doxycycline Minocycline Fluroquinolones...
Pharmacology
Anti Microbial
0ca7321f-a164-4bbf-bd4d-5e29639193de
A 26 year old female patient complains of discoloration with her upper front teeth. Intra-oral examination reveals intrinsic staining with maxillary incisors. Dentist prepares the tooth to receive veneers. This type of margin design is called as:
Chromatic induction
Blending effect
Chromatic assimilation
Complimentary after image
1b
multi
The blending effect is predominantly related to smaller restorations, surrounded by hard dental tissues, such as composite restorations. It can reduce suboptimal shade matches due to operational error or lack of satisfactory match in the shade guide or restorative material. The veneers designed with “contact lens effec...
Dental
null
a6106bbf-6619-4bff-9bd0-52adc9743a5b
A 2 year old born out of consanguineous marriage, had a history of the collodion membrane. He had large, thick, plate-like brown scaling generalized distribution; no erythroderma and ectropion. Which disease is it?
Ichthyosis vulgaris
Lamellar ichthyosis
X linked ichthyosis
Netherton syndrome
1b
single
Ans. B. Lamellar ichthyosisLamellar ichthyosis (LI)* Collodion baby at birth as the baby is covered by a thickened collodion-like membrane which is then shed* Scaling occurs over the whole body, including creases and bends* The scale in LI is typically large, dark brown or grey and firmly adherent* Drooping of lower ey...
Skin
Autoimmune Skin Disorders
4d7e2f91-de4c-4f2e-b15f-453b1d3ac421
Carey coombs murmur, which is false -
Delayed diastolic murmur
Seen in rheumatic fever
Can be associated with A.R.
Low pitched murmur
0a
multi
A sho, mid-diastolic murmur is rarely heard during an episode of acute rheumatic fever (Carey-Coombs murmur) and probably is due to flow through an edematous mitral valve. An opening snap is not present in the acute phase, and the murmur dissipates with resolution of the acute attack. Complete hea block with dyssynchro...
Medicine
C.V.S
ec8b1d4b-64bf-4e3c-8458-24bfdcecd3f4
Tolvaptan is approved for use in-
High Na
High K
High Ca
Low Na
3d
single
Tolvaptan is a vasopressor receptor antagonist used to correct hyponatremia in the treatment of syndrome of inappropriate water excretion or SIADH :- Syndrome of inappropriate secretion of ADH is caused due to excesive secretion of antiduretic hormone. Antidiuertic hormone (ADH) or arginine vasopressin is synthesized b...
Medicine
null
3399ff3f-7028-4e39-b66b-677182676f09
Organ most vulnerable to ischaemic due to shock?
Lungs
Adrenals
Kidney
Hea
3d
single
Ans. is 'd' i.e., Hea o The susceptibility of a tissue to hypoxia influences the likelihood of infarction. o Neurons are most sensitive to hypoxia (irreversible changes develop in 3-4 minutes) followed by myocardial cells (irrversible changes develop in 20-40 minutes). o Fibroblasts are amongst the most resistent cells...
Pathology
null
2ec73e7d-7ab4-4724-8bc5-fb2213dd5217
After premature delivery, mother's milk is low in
Lactose
Fat
Protein
Sodium
0a
single
Ans. a (Lactose) (Ref OP Ghai 6th/ p. 158; 7th/p. 131, 134)After premature delivery, mother's milk is low in:# Calcium # Phosphates # LactoseADVANTAGES OF BREAST MILK# Docosahexanoic acid (DHA, W3, 2:3) present in breast milk helps in brain development.# Maximum synthesis of breast milk occurs at 12 months.# Has better...
Pediatrics
Nutrition
9a7f7050-8067-49b8-a7df-3ea1ba8be6d6
Alkaline douch solution of nose does not contain:
NaCI
Na biborate
NaHCO3
Glucose
3d
single
Ans. D Nasal irrigation and removal of crusts - warm normal saline or an alkaline solution made by Soda bicarbonate 1 pa Sodium biborate 1 pa Sodium chloride 2 pas in 280 ml of water Initially irrigation are done 2 or 3 times a day but later every 2 or 3 days is sufficient 25 % glucose in glycerine - nose is painted th...
ENT
null
5b4630c7-2b51-4cae-9ecc-370afbf2e23c
True about tumor lysis syndrome -a) Hyperkalemiab) Hypercalcemiac) Lactic acid d) Hyperuricemia
b
c
ad
ab
2c
multi
null
Medicine
null
ed04d2ca-75c4-4457-91c9-2703ce978cec
Shoest acting anticholinesterase is -
Edrophonium
Pyridostigmine
Glycopyrrolate
Neostigmine
0a
single
Ans. is 'a' i.e., Edrophonium o Edrophonium is the shoest acting anti-ChE. o Why is it so, lets see : o When carbamates (other than edrophonium) and organophophates react with cholinesterase, they form covalent bond at esteratic site, which is considerably resistant to hydrolysis. o In contrast, edrophonium binds elect...
Pharmacology
null
4798c743-8cf8-4d88-af53-00a9f0f38233
Injury to the nerve originating from C5 in Brachial plexus leads to
Loss of abduction of the arm
Loss of abduction of arm
Loss of shrugging
Winging of scapula
3d
single
The question speaks of Dorsal scapular nerve on whose damage leads to winging of scapula.
Anatomy
null
a7119740-e261-4096-bcf2-1057f1d7fb87
All of the following are presentin pterygomandibular space except
Nerve to mylohyoid
Chorda tympani
Long buccal nerve
Nerve to pterygoid
2c
multi
null
Surgery
null
312d1060-29c3-4274-b6cf-917ae47e2774
Which of the following features is not included in psychosis
Panic attack
Delusion
Hallucination
Hypochondriasis
0a
multi
A i.e. Panic attack - Hypochondrial symptoms are commonly present in major depression. Panic attacksQ (generalized anxiety disorder) is a neurotic disorder Delusion & hallucinations are common in psychosis (MDP, Schizophrenia & delusional disorder).
Psychiatry
null
8993517f-dd2f-423c-bf2a-7b90b166ac70
True about composition of hospital waste
Metal 1%
Paper 10%
Glass 5%
Infectious waste 3%
0a
multi
- the average composition of hospital wastes in India is; - 15% - 10% metals- 1% infectious wastes-1.5% -4% wastes-53.5% Reference : Park&;s textbook of preventive and social medicine, 23rd edition, pg no:790, table 2. <\p>
Social & Preventive Medicine
Hospital waste and disaster management, Occupational health
86f8feb0-f026-4da8-b435-21e419b33520
Spring catarrah is -
Type I hypersensitivity reaction
Type II hypersensitivity reaction
Type III hypersensitivity reaction
Type IV hypersensitivity reaction
0a
single
It is considered a hypersensitivity reaction to some exogenous allergen, such as grass pollens. VKC is thought to be an atopic allergic disorder in many cases, in which IgE-mediated mechanisms play an impoant role. Such patients may give personal or family history of other atopic diseases such as hay fever, asthma, or ...
Ophthalmology
Conjunctiva
ac085ab5-8ae3-4d2c-9866-f0021a4a16da
Most common histological type of thyroid carcinoma is
Follicular type
Papillary type
Anaplastic type
Medullary type
1b
single
(B) Papillary type # Morphological variants of thyroid carcinoma and their approximate frequencies are: Papillary carcinoma 75-85% Follicular carcinoma 10-20% Medullary carcinoma 5% Anaplastic carcinoma < 5%> Histology type Incidence Papillary 80% Follicular 10% Medullary 5% Anaplastic 1 %> Papillary carcinoma thyroid:...
Pathology
Misc.
d96514ac-dca9-4ac0-bd27-95e785f9ef9d
Which vitamin deficiency may be observed in a patient on INH therapy: September 2012
Thiamine
Pyridoxine
Folic acid
Cyanocobalamin
1b
single
Ans: B i.e. Pyridoxine The main cause of pyridoxine deficiency is a lack of pyridoxine in the diet. Another cause of vitamin B6 deficiency is the use of the ATT medication isoniazid, and for this reason, it is usually replaced with vitamin B6 whilst using this drug.
Social & Preventive Medicine
null
3d08747d-9694-4d5c-84a1-8a3b41b03dbd
Hypersegmented neutrophils are seen in -
Microcytic hypochronic anemia
Sideroblastic anemia
Megaloblastic anemia
Hemolytic anemia
2c
single
Ans. is 'c' i.e.. Megaloblastic anemia Findings of megaloblastic anemiaPeripheral bloodo Macrocytosis i.e., megaloblastic RBC - Due to nuclear1 cytoplasmic asynchrony,o Macrocytes lack central pallor of normal RBC.o Anisopoikilocytosis - Marked variation in shape and size,o Majority of RBCs appear as macroovalcytes.o F...
Pathology
Iron Deficiency and Megaloblastic Anemia
3aca2a61-46f1-4168-8bf3-a70ec5b2e199
A 20-year-old male presented with high-grade fever, groin pain and a swollen scrotum for 1 week and are worsening progressively. On examination, Tender inguinal lymphadenopathy Scrotal swelling with hydrocoele Lymphatic streaking Blood samples are taken and a parasite infection is suspected. Which of the following is t...
<img style="max-width: 100%" src=" />
<img style="max-width: 100%" src=" />
<img style="max-width: 100%" src=" />
<img style="max-width: 100%" src=" />
0a
single
This is a case of filariasis (acute lymphadenitis) due to Wuchereria bancrofti. Microfilariae are found in blood, hydrocoele and other body fluids. 1 Wuchereria bancrofti Sheath, no nuclei in the tip of the tail 2 Brugia malayi Sheath, 2 distinct nuclei in the tip of the tail 3 Loa loa Sheath, nuclei extending to the t...
Unknown
Integrated QBank
dd755682-e45e-4b37-a222-dbff9ad1e189
All causes brain lesions except
Giardiasis
Tuberculosis
Cysticercosis
Bacteriodes
0a
multi
giardiasis is caused by Giardia lamblia. the parasite attaches itself to the epithelial surface of duodenum and jejunum and causes disturbance of intestinal function leading to malabsorption of fat. Patient presented with loose stool and mild steatorrhoea. .Baveja textbook of parasitology 3rd edition.
Microbiology
parasitology
439a726c-f0ca-4451-bf8b-ec409f322991
All of the following metabolic pathways occur in both Cytoplasm and Mitochondria, except:
Glycolysis
Gluconeogenesis
Heme Synthesis
Urea cycle
0a
multi
Ans. (a) GlycolysisRef.: Harpers Biochemistry 30th edti. /142-144* Glycolysis occurs in cytoplasm.* There are two major sites for gluconeogenesis, the liver and the kidneys.* The liver accounts for 90% of gluconeogenesis in the body and the remaining 10% occur in the kidney and other tissues of the body.* The liver and...
Biochemistry
Glycolysis
defafb75-e1d8-454c-84fe-a326151e3cba
Shailza, a 40-year-old female is having headache for the past 6 months. All her investigations were normal. She had several consultations and she had no relief of her symptoms. She still believes that she has some problem in her brain. Likely diagnosis could be: September 2010
Acute mania
Acute depression
Psychogenic headache
Hypochondriasis
3d
multi
Ans. D: Hypochondriasis Hypochondriasis, hypochondria refers to excessive preoccupation or worry about having a serious illness. An individual suffering from hypochondriasis is known as a hypochondriac. Often, hypochondria persists even after a physician has evaluated a person and reassured them that their concerns abo...
Psychiatry
null
736c6adb-0648-419b-a850-cb7379f04dec
Not a feature of acute aerial Occlusion ?
Cyanosis
Pallor
Paralysis
Paraesthesia
0a
multi
Ans is 'a' ie Cyanosis
Surgery
null
fa86d16d-c0e7-4f0c-8b5b-4334a40e19be
Bajaj committee in 1986 proposed?
Multipurpose health worker
Manpower and planning
Rural Health Service
Integrated health services
1b
single
<p> Manpower and planning. Reference:India health repo 2010,page no;132. <\p>
Social & Preventive Medicine
Health education & planning
7a64fd0e-3505-4017-a612-4124738978e1
Instrument of choice for diagnosing pediatric retinal disorders
OCT
Fluorescein angiography
Slit lamp examination
Retcam
3d
single
Retcam has been used to diagnose pediatric retinal disorders. It has a probe which is put over eye which captures the fundus photo. It can also do fluorescein angiography and is used for tele consultation too High Yield Facts *Factors responsible for ROP : Low GA is more impoant than LBW *WHO Vision 2020 program target...
Ophthalmology
Diagnosis and Treatment of Retina
85c50675-b971-457a-b2f4-e15e3a5383b1
Brunner's glands are seen in -
Jejunum
Upper duodenum
Lower duodenum
Appendix
1b
single
The presence of mucous duodenal (Brunner’s) glands in the submucosa is indicative of upper duodenum. These submucosal glands are absent in the jejunum, ileum and the entire large intestine.
Anatomy
null
046eafd2-e90d-425f-94b1-75bf61df7077
All are seen in injury to common peroneal nerve except?
Loss of sensation over sole
Foot drop
Injury to neck of fibula
Loss of dorsiflexion of toe
0a
multi
A i.e. Loss of sensation ove soleSole is supplied by medial & lateral plantar and sural branches of tibial nerveQ anteriorly (from medial to lateral) and calcaneal branches of tibial nerveQ posteriorly (i.e. over heel). So it is not affected in common peroneal nerve injury.
Anatomy
null
a899124d-9293-4957-b749-a0d651f1e12b
Haemoglobin can bind to all the following except
O2
CO2
SO2
NO
2c
multi
Ans: c (SO2) Ref.Ganong 22nd ed/p.667.Hb does not bind to SO2.Functions of Hb:-It facilitates 02 transportIt facilitates C02 transportIt has an important role as a bufferIt transports NO.Hemoglobin binds NO in the lungs and releases it in the tissues, where it promotes vasodilation.In arterial blood,Total volume of C02...
Physiology
Heart, Circulation, and Blood
c6d70c86-332a-42dc-b895-bbdabee2616e
Cadaveric spasm -a) Immediate after deathb) After 2 hours of deathc) Affects voluntary musclesd) Affects involuntary muscle
ac
bc
ad
b
0a
single
Cadaveric spasm occurs immediately after death and affects voluntary muscles.
Forensic Medicine
null
34975b3c-3521-4bfc-a8df-08f14d7e803a
The treatment of acute myocardial infarction includes which of the following-
Aspirin
Heparin
Alteplase
Oral anticoagulants
0a
single
Ref : harrisons-manual-of-medicine-16th-edition pg no: 622-623 TREATMENT Initial Therapy Initial goals are to: (1) quickly identify if patient is candidate for reperfusion therapy, (2) relieve pain, and (3) prevent/treat arrhythmias and mechanical complications. * Aspirin should be administered immediately (162-325 mg ...
Medicine
C.V.S
7fa5f474-c88c-4ed6-916e-c57284e9a0e9
An 8 year old boy presented with fever and bilateral cervical lymphadenopathy with prior history of sore throat. There was no hepatomegaly. The peripheral blood smear shows > 20% lympho-plasmacytoid cells. The most likely diagnosis is -
Influenza
Tuberculosis
Infectious mononucleosis
Acute lymphoblastic leukemia
1b
single
Ans. is 'b' i.e., Infectious Mononucleosis Infectious mononucleosis Infectious mononucleosis : Is the most characteristic disease produced by Epstein Barr Virus Clinical features : o Most infections are asymptomatic. o Headache, Abdominal pain, chills also seen in few casees. o Fever, malaise, sore throat, (exudative p...
Pediatrics
null
7ee59789-0e99-41a6-8a87-604945abd900
In surgical anterolateral approach to tibia, incision is taken over the tibialis anterior muscle mass rather than over the shaft. What is/ are the advantages?
Medially based flap
Less chances of wound dehiscence
Can be converted to an extensile approach
All the above
3d
multi
Ans. is 'd' i.e., All the above * In surgical anterolateral approach to tibia, incision is taken over the tibialis anterior muscle mass rather than over the shaft. Following are the advantages :i) If required can be converted to an extensile approach. Entire tibia from knee to ankle can be exposed.ii) Open wound treatm...
Orthopaedics
Management In Orthopedics
284dc3e6-4bfb-48f9-862b-5dda7e7a7d7a
A young patient had a history of fall. The physician placed his hand on the patient's chin and instruct him to rotate his head to the opposite side against resistance. But he was unable to perform the action. Which of the nerve is injured in this patient?
Posterior auricular nerve
10th cranial nerve
Spinal accessory nerve
12th cranial nerve
2c
multi
The sternocleidomastoid muscle creates the borders for both the anterior and the posterior triangles of the neck, and is innervated by the spinal accessory nerve (CN XI). To test the sternocleidomastoid muscle, the physician will place her hand on the patient's chin and instruct him to rotate his head to the opposite s...
Anatomy
null
92e4ebb2-1c28-402e-94af-5fc516bfb9a6
Most common cause of death in measles is
Pneumonia
Meningitis
Dehydration
Encephalitis
0a
single
.
Anatomy
All India exam
cf2b51ac-c907-4747-86a7-f1f5ee3aef86
One of the following infections is caused by anaerobic gram positive cocci
Puerperal infection
Food poisoning
Endocarditis
Septicemia
0a
single
null
Microbiology
null
ebb44820-9311-4045-adb8-586ac02bc22e
IQ in mild mental retardation is
50-70
35-49
20-34
< 20
0a
single
Ans. is 'a' i.e., 50-70
Social & Preventive Medicine
null
d6c85d1d-0ecb-4b19-83dd-34358d525c9f
Reticulocytosis is NOT a feature of:
Paroxysmal nocturnal hemoglobinuria
Following acute bleeding
Hereditary spherocytosis
Anemia in CRF
3d
single
Answer is D (Anemia of chronic Renal Failure) Anemias of chronic renal failure and chronic disease are associated with low or normal reticulocyte counts. Elevated reticulocyle count is a feature of hyperproliferative anemias including PNH, hereditary spherocytosis and anemia after blood loss.
Medicine
null
4c88274a-ce9c-408c-91f6-0a021d055d62
Feline esophagus is seen in:
Eosinophilic esophagitis
Radiation esophagitis
GERD
Carcinoma esophagus
0a
single
- Feline esophagus is seen in both Eosinophilic Esophagitis>GERD. It is characteristic of Eosinophilic esophagitis so it serves as a better answer. - Eosinophilic Esophagitis: A barium swallow should be the first test obtained in the patient with dysphagia EE has a characterised finding often called the "Ringed esophag...
Surgery
Esophagus
b5cb2e88-896f-487e-9569-baac957ab7b3
A drug which is not used to provide conscious sedation in a child is
Nitrous Oxide
Chloral Hydrate
Hydroxyzine
Lincomycin
3d
single
null
Dental
null
b7ea2f57-a51f-42ef-b61c-c763ffeeda11
Lady with infeility with bilateral tubal block at cornua : best method of management is :
Laparoscopy and hysteroscopy
Hydrotubation
IVF
Tuboplasty
2c
single
IVF
Gynaecology & Obstetrics
null
e4405a08-da20-4973-912c-844267b940d7
Local anesthetic action is a result of blockade of the movement of wof channels
Chloride
Sodium
Potassium
Calcium
1b
single
LOCAL ANAESTHETICS MECHANISM OF ACTION The LAs block nerve conduction by decreasing the entry of Na+ ions during upstroke of action potential (AP). As the concentration of the LA is increased, the rate of rise of AP and maximum depolarization decreases causing slowing of conduction. Finally, local depolarization fails ...
Pharmacology
Anesthesia
ae249d6e-5948-4bda-bd37-e4981451aba2
Odd pair -
Erythema marginatum-rheumatic fever
Erythema gyrens ripens-malignancy
Necrotic acral erythema-HCV
Erythema chrcnieum migrans ->> malignancy
3d
single
Ans. is 'd' i.e., Erythema chronicum migrans - malignancyo "Erythema gvratum repens" is a rare and characteristic rash strongly associated with malignancy .It consists of wavy erythematous concentric bands that can be figurate, gyrate or annular.These bands are arranged in parallel rings and lined by a fine trailing ed...
Medicine
Skin
bd7a581b-a501-4663-a16a-53a86a2e1e0e
Flapping tremors are seen in the following conditions except -
Uremic encephalopathy
Parkinsonism
Hepatic encephalopathy
Carbon dioxide narcosis
1b
multi
null
Medicine
null
d1ea5a78-b45d-412d-a69b-414292ce6fab
All of the following are true about rituximab except?
Chimeric monoclonal antibody against CD-20 B cell antigen
Most common side effect is infusion reaction
First FDA drug approved for resistant lymphomas
Dose independent pharmacokinetics
3d
multi
Ans. d. Dose independent pharmacokinetics (Ref: Harrison 19/e p2147,18/e p2749; Katzung 12/e p646; htt[://www.isdbweb. org/documents/file/1442_2pdf)Pharmacokinetics of rituximab (monoclonal antibodies) is dose dependent.'The rate of uptake and elimination of antibodies by target-mediated pathways is a function of dose ...
Pharmacology
Immunomodulator
123467c9-e972-45f6-9265-a8f04b07c4c7
NOT a constituent of embalming fluid: AIIMS 08
Formalin
Methanol
Ethanol
Glycerin
2c
single
Ans. Ethanol
Forensic Medicine
null
3a4a5ffc-572c-41e1-b457-b13cd305f4aa
Which of the following is true of mumps ?
Salivary gland involvement is limited to the parotids
The patient is not infectious prior to clinical parotid enlargement
Menigoencephalitis can precede parotitis
Mumps orchitis frequently leads to infeility
2c
multi
Ans. is 'c' i.e., Meningoencephalitis can precede parotitis "Aseptic meningitis may develop before, during, after or in the absence of parotitis." About other options o Mainly parotid glands are involved, but sublingual and submaxillary glands may also be involved. o Patient is infectious 4-6 days before the onset of s...
Pediatrics
null
e35296fd-32b6-49e5-a3c7-8615c618db13
Which of the following is not a characteristic finding in Henoch Schonlein Purpura?
Palpable purpura
Nephritis
Thrombocytopenia
Abdominal pain
2c
single
Henoch Schonlein Purpura is a small vessel vasculitis characterized by palpable purpura, ahralgia, gastrointestinal signs and symptoms and glomerulonephritis. Patients have a normal platelet count, other laboratory findings includes mild leukocytosis, occasional eosinophilia, normal serum complement and elevated IgA. R...
Medicine
null
8013bdb3-f6f8-418a-94b5-2a1e5650c6e4
False statement about selegeline is -
It is a MAO -A inhibitor
Does not cause cheese reaction
May be used in on - off phenomenon
It is used in parkinsonism
0a
multi
Ans. is 'a' i.e., It is a MAO-A inhibitor o Selegeline (deprenyl) inhibitis MAO-B o Unlike nonselective MAO inhibitors, selegiline in low doses does not interfere with peripheral metabolism of dietary amine (tyramine), accumulation and hypeensive reaction (cheese reaction) does not develop, while intracerebral degradat...
Pharmacology
null
53a1e252-785f-4720-b5df-bee628aa588d
Most common cause of ARDS in children is:
Aspiration
Injury
Severe pneumonia with sepsis
DIC
2c
single
c. Severe pneumonia with sepsis(Ref: Neonatal and Pediatric Respiratory Care 4/e By Brian K. Walsh p 564)Pneumonia, sepsis and aspiration are the most common cause of ARDS and ALI in children
Pediatrics
Respiratory System
05625285-f8ba-4ab9-b7c7-5f1ec19b9da0
The most frequently implicated antibiotic among the causes of drug induced liver injury is:
Tetracycline
Amoxicillin-clavulanic acid
Erythromycin
Nalidixic acid
1b
single
Amoxicillin-clavulanic acid : The most frequently implicated antibiotic among cases of drug-induced liver injury. Reference: Harrisons Principles of Internal Medicine, 18th Edition, Page 2560
Medicine
null
60f357fb-7cd1-4746-8a4e-558026bca2bc
Which of the following is a nonmodifiable risk factor for coronary hea disease?
Cigarette smoking
Elevated serum cholesterol
Alcoholism
Age
3d
single
park's textbook of preventive and social medicine 23rd edition. *non modifiable risk factors for CHD :age,sex,ethnicity, genetic factors. *modifiable risk factors: obesity,alcohol,physical activity, saturated fat, socio-economic status.
Social & Preventive Medicine
Non communicable diseases
9ba9ffba-d069-4f11-8b9e-1e6a637e39e1
Families which lags behind rest of community, is known as
Communal family
Elementary family
Problem Family
Broken Family
2c
single
Problem Family: Is a family which lags behind rest of the community; underlying factors in most problem families are those of personality, relationships, backwardness, povey, illness, mental and social instability, character defects and marital disharmony. Standards of life are generally far below the accepted minimum ...
Social & Preventive Medicine
Social science, Mental health & Genetics
d5691789-8391-484e-9cbd-83d047dcf4dd
The serum concentration in which of the following human IgG subclasses is maximum?
IgG1
IgG2
IgG3
IgG4
0a
single
IgG 1 - 65%, IgG2- 23%. IgG3 -8% IgG4 - 4%
Physiology
Immunology
a942906f-ed09-4b02-a88e-d246f207d122
29 year old female with history of Sjogren's syndrome presents with a 2 day episode of watery diarrhea 2 days ago. Physical examination is unremarkable. Because of her history, the physician decides to check her urine electrolytes. Urine chemistry: K = 31, Na = 100, Cl = 105. Her current diagnosis is?
Renal tubular acidosis
Hypochloremic Metabolic alkalosis
Malignant hypeension
Respiratory alkalosis
0a
single
* The urine electrolytes are used to distinguish between A and diarrhea * UAG is an indirect measure of ammonium excretion * UAG = (Na + K) - Cl * UAG = ( 100 + 31 ) - 105 = 26 * A positive UAG suggest A because in the setting of diarrhea, ammonium chloride concentration in the urine would be high and the UAG would be ...
Medicine
Electrolyte Imbalance
e0dd2825-0d58-4a03-bf57-cde3dd54c572
Prolonged latent phase is seen in :
Placenta prae
Unripe cervix
Abruptio placenta
Excessive sedation
1b
single
In primi, the latent phase is often long (about 8 hours) during which effacement occurs; the cervical dilatation averaging only 0.35 cm/hr. In multi, the latent phase is sho (about 4 hours) and effacement and dilatation occur simultaneously. Latent phase is the preparatory phase of the uterus and the cervix before the ...
Gynaecology & Obstetrics
General obstetrics
062c5fdc-ea77-45f5-b855-9e1e6e0f958f
A 60-year-old female is having proximal muscle weakness with increased serum creatinine kinase. The probable diagnosis is:
Polymyositis
Dermatomyositis
Inclusion body myositis
Limb-girdle muscle dystrophy
0a
single
A. It is a subacute inflammatory myopathy affecting adults, without rash, involvement of eye, family history of neuromuscular disease B. Dermatomyositis is identified by a rash preceding muscle weakness. C. Inclusion body myositis has an asymmetrical muscle involvement. D. Limb girdle muscular dystrophy and would have ...
Medicine
Guillian Barre syndrome & Alzheimer's disease
35ef32f6-7c09-476f-a0d1-7aa933002ce9
Translocation between the 2 acrocentric chromosomes with breakpoint occurring close to the centromeres, so that very large and very small chromosomes are obtained from which smaller fragment is usually lost. The type of cytogenic abnormality is:
Deletion
Balanced translocation
Robertsonian translocation
Inversion
2c
multi
null
Pathology
null
5283eab9-9ab4-427a-ae3e-ac6728dbb51a
You are in the causlity when a student, Kumar is brought in with a shoulder injury sustained while playing football. In comparing the symmetry of his two shoulders, you notice a marked elevation of the distal end of his clavicle with respect to the acromion on the injured side. X-ray exam reveals a grade III shoulder s...
Coracoacromial
Coracoclavicular
Costoclavicular
Superior glenohumeral
1b
multi
A shoulder separation is an injury to the acromioclavicular joint. A first degree separation involves stretching the ligaments, but maintenance of the joint. A second degree separation involves tearing of the joint capsule and coracoclavicular ligament, but still continuity. A third degree separation involves total dis...
Anatomy
null
82b0912c-4604-46cd-87a3-d2180c544484
A 45 years old lady present with a lump in her right breast. The lump is 4 cms in diameter with evidence of cutaneous oedema (peau d' orange), not fixed to pectoralis major muscle. The axillary lymph nodes are not enlarged. What is the status of T in T.N.M. classifcation.
T 1 >2
T 2 is 2-5
T 3 > 5
T 4 is any size
3d
single
null
Surgery
null
b96c2aa5-6b98-4330-9da7-697bfdaf18df
Hemolytic Uremic Syndrome is characterized by -a) Microangiopathic haemolytic anaemiab) ↓ed LDHc) Thrombocytopeniad) Renal failuree) Positive Coomb's test
abc
ad
acd
bde
2c
single
Hemolytic uremic syndrome Hemolytic uremic syndrome is characterized by the triad of : Anemia (microangiopathic hemolytic anemia). Renal failure (microangiopathy of kidney involving glomerular capillaries and arterioles). Thrombocytopenia (due to platelet consumption). Hemolytic uremic syndrome is most common is c...
Pathology
null
aa61340f-5a57-4f95-869f-c69d425d4d46
All of the following antihistaminic agents lack anticholinergic property EXCEPT :
Promethazine
Astemizole
Levocetirizine
Loratadine
0a
multi
All the drugs listed in the question are second generation anti-histaminic agents except promethazine.
Pharmacology
null
feb69838-3165-446f-aa36-97887d37ddd2
Totipotency of embryonic stem cell is due to that they?
Can differentiate into all the tissues of embryonic or extraembryonic cell types.
Can differentiate into cells derived from any of the three germ layers.
Can differentiate only into cells of a closely related family
Can differentiate only in to one cell type
0a
multi
Ans. is 'a' i.e., Can differentiate into all the tissues of embryonic or extraembryonic cell types Stem cells base on their potency* Potency refers to ability of stem cells to differentiate into specialized (mature) cell type:-A. Totipotent stem cells - These cells are produced from fertilization of sperm and ovum and ...
Pathology
Misc.
b20e5f67-d0fb-41e5-90fb-a3541f40e6b3
Copper -- T is preferably inseed postnatal after :
2 weeks
4 weeks
5 weeks
8 weeks
3d
single
8 weeks
Gynaecology & Obstetrics
null
b9b25be7-b40f-41fb-bf75-c812c05fba22
Stress concentration in Root dentin is least with:
Smooth tapered post.
Serrated tapered post
Smooth parallel post.
Serrated parallel post
2c
multi
null
Dental
null
de5f8dd7-fa2d-4426-80c0-e64a861cf218
Pneumothorax of what size generally needs operative treatment?
>10%
>20%
>30%
>40%
1b
multi
Small pneumothoraxes (<20%) that are stable may be monitored if the patient has few symptoms Moderate (20%-40%) and large (>40%) pneumothoraxes nearly always are associated with persistent symptoms that cause physical limitations and require intervention.
Surgery
Thorax And Mediastinum
64cd27ee-3ebb-44d8-bbc5-bde4f1372859
Which of the following is the cause of break of glomerular basement membrane sometimes and sub epithelial deposits in electron microscopy?
Membranous glomerulonephritis (MGN)
Focal glomerular sclerosis
Rapidly progressive glomerulonephritis (RPGN)
Minimal change (MCD)
0a
single
null
Pathology
null
188d59fb-9853-4ae1-a34c-9987916750ad
Most Common extranodal site of Lymphoma in 14W is?
CNS
GIT
Retroperitoneum
Mediastinum
0a
single
Ans. is 'a' i.e., CNS
Pathology
null
722b37ff-b8a8-4a81-adee-8b989862bbaa
Which one of the following stains is specific for Amyloid?
Periodic Acidschif (PAS)
Alzerian red
Congo red
Von -Kossa
2c
single
Ans. is 'c' i.e., Congo Red "To differentiate amyloid from other hyaline deposits (eg. Collagen andfibrin), a variety of histochemical techniques are used, of which the most widely used is Congo Red " - Robbins 7th/e p. 259Staining for Amyloido Congo red : It is the most widely used specific stain for amyloid.o Iodine ...
Pathology
Amyloidosis
a80aaae5-f91f-4a08-970b-e3a333f146a1
Physiological uncoupler is ?
Thyroxine
Free fatty acids
Thermogenin
All of the above
3d
multi
Ans. is 'd' i.e., All of the above
Biochemistry
null
d3619749-4faf-4fb8-bf1f-2e91b073ddee
Type II hypersensitivity -
Blood transfusion reaction
Ahus reaction
Hay Fever
Glomerulonephritis
0a
single
autoimmune haemolytic anaemia, transfusion reactions,idiopathic thrombocytopenic purpura,graves disease,myasthenia gravis are the examples of type 2 hypersensitivity.Harshmohan textbook of pathology 7th edition
Pathology
General pathology
22406660-e64a-4016-ae26-0cdcd6306da5
Drug used in mild hemophilia is :
Corticosteroids
DDAVP
Vitamin K
Tranexamic acid
1b
single
null
Pharmacology
null
1ed7b8c9-d9d9-4d83-953c-a8e8751f62b9
Gas gangrene is caused by: March 2012
Clostridium welchii
Clostridium tetani
Clostridium botulinum
Clostridium difficile
0a
single
Ans: A i.e. Clostridium welchii Conditions and pathogens Established pathogens (clostridium) for gas gangrene (group) includes Cl. Perfringens/ welchii, Cl. septicum & Cl. Novyi Established pathogen (clostridium) for tetnaus include Cl. Tetani Established pathogens (clostridium) for food poisoning (group) includes Cl. ...
Microbiology
null
8f1098e1-cdd8-457b-bc2c-7282e8f44191
The main enzyme responsible for activation of xenobiotics is -
Cytochrome P-450
Glutathione S-transferase
NADPH cytochrome P-450-reductase
Glucuronyl transferase
0a
single
Most important reaction in biotransformation of xenobiotics is oxidation reaction. The most important enzyme for oxidation reactions is cytochrome P450.
Biochemistry
null
a3fd413e-d69e-40da-b800-5333af840d1b
ABC transpoer ?
P. glycoprotein
Membrane sparing
Channel
Adenylyl cyclase
0a
single
Ans. is'a' i.e., P. glycoproteinATP-binding cassette transpoers (ABCtranspoers) are integral transmembrane proteins that utilize ATP as an energy source to translocate a variety of substrates across membranes.P-glycoprotein is an ATP-binding cassette (ABC) transpoer and is an impoant factor to limit membrane permeabili...
Physiology
null
bac89777-4154-495f-9879-73e50f62ea56
Site where endolymph is seen:
Scala vestibuli
Scala media
Helicotrema
Scala tympani
1b
single
(b) Scala media(Ref. Scott Brown, 8th ed., Vol 2, page 545)Endolymph is present in the membranous labyrinth, whereas perilymph is present in the bony labyrinth.Hence scala vestibuli, scala tympani and their interconnection helicotrema, which are parts of bony labyrinth, are filled with perilymph.Scala media, utricle, s...
ENT
Ear
6fbdc56a-d6bd-47b2-86ad-650a2567a74e
Which of the following drug is an inverse agonist at H3 receptors used for Narcolepsy?
Dexmedetomidine
Pitolisant
Icatibont
Secukinumab
1b
single
Pitolisant (Tiprolisant) is a inverse agonist of H3 receptors approved for Narcolepsy. H3 receptors are presynaptic receptors and inverse agonist will lead to increased histamine release and promote wakefulness.
Pharmacology
null
2ad2256f-8fba-45b6-bd7c-92418ada1c38
Not true regarding Pectus excavatum?
Heart shifted towards left side
Features may suggest RML consolidation
Anterior ribs are more vertically oriented - 7 shaped ribs
Heart shifted towards right side.
3d
multi
Ans DIn pectus excavatum the heart is shifted towards left side. As right heart border goes behind the sternum it is obscured and can thus mimic right middle lobe disease.
Radiology
Respiratory System
853b3810-0e19-4d66-9700-0cb01f81effd
Whip-lash' injury is caused due to
A fall from a height
Acute hyperextension of the spine
A blow on top to head
Acute hyperflexion of the spine
1b
multi
B i.e. Acute hyperextension of the spine
Forensic Medicine
null
a583bb96-e6fe-45cb-95f2-43cf7430f2c0
How to differentiate between staphylococci and micrococci?
Catalase test
Modified Oxidase test
Gram staining
AFS
1b
single
Micrococci:Micrococci are gram-positive cocci which occur mostly in pairs, tetrads or irregular clusters. They are catalase and modified oxidase positive and aerobic. They are ordinarily non-pathogenic. The resemble Staphylococci, but in general, they are large in size and tetrads. The common laboratory test used to di...
Microbiology
Bacteriology
86b330e6-2d86-4b03-8a93-003d3de4f8ae
Following are the factors for increased risk of wound infection EXCEPT
Malnutrition
Good blood supply
Metabolic diseases (diabetes, uraemia)
Immunosuppression
1b
multi
Ans. (b) Good Blood Supply(Ref. Surgery Sixer 3rd Edition Page 33)Systemic Factors causing non healing of Wound:* Diabetes* Radiation* Extremes of age* Hypothermia* Hypoxemia* Hypocholesterolemia* Hyperglycemia (Even if transit)* Malnutrition* Vitamin C and A deficiency* Zinc and Iron deficiency* Drugs: Steroids and Do...
Surgery
Miscellaneous
553e0c4a-95de-471f-8ef1-309e50b0d95a
Therapeutic aboion was accepted by
Declaration of Genava (1948)
Declaration of Oslo (1970)
Declaration of Helsinki
Declaration of Tokyo
1b
single
Ans. is 'b' i.e., Declaration of Oslo (1970)
Social & Preventive Medicine
null
bc51f4f4-53b3-47fc-942e-5002fe8b78d8
A patient presents with intense chest pain of 2 hrs duration ECG shows ST depression in leads I and V1 to V4. There is associated T inversion and CPK-MB is elevated. Which of the following should be included in his management
Nitroglycerine drip
Aspirin
i.v. metoprolol
All of the above
3d
multi
null
Medicine
null
1e8102fa-8144-434e-a6cf-0f95c19ee207
Which of the following is the Post - Chemotherapy based staging system used in Wilm's tumor?
National Wilm's Tumor Staging System (NWTSG)
International Society of Pediatric Oncology (SIOP)
AJCC TNM Staging
Chadwick Staging
1b
single
International Society of Pediatric Oncology-SIOP staging system is the post - chemotherapy based staging system used in Wilm'stumor. Protocol of SIOP consists of initial clinical staging by physical examination, radiologic examination and neoadjuvant chemotherapy. The tumor burden is reduced by preoperative chemotherap...
Surgery
null
44b56bd3-5c0b-4929-a548-8a9bdff1a1c3
Which of the following is TRUE regarding Neisseria meningitidis infection?
It is the most common cause of meningitis in children
All strains are uniformly sensitive to sulfonamides
Vaccines are contraindicated in immunosuppressed
In India serotype B is most common cause
0a
multi
For children >3 months old, the most common organisms are S. pneumoniae, Neisseria meningitidis, and Staphylococcus aureus, with a lower incidence of S. pneumoniae meningitis since routine vaccinations with the conjugate vaccine. Penicillin has long been the treatment of choice for meningococcal infections and sulfonam...
Microbiology
null
ee4a2721-0deb-4b1c-838b-295c33fecb6f
All are true about Retained Antrum Syndrome except:
Technetium 99 m scan is used for diagnosis
Seen after Billroth II surgery
Positive Secretin Stimulation Test
Calcium Provocation test is negative
2c
multi
Ans. (c) Positive Secretin Stimulation testRef: Internet SourcesRetained Antrum Syndrome:* A complication following Billroth 2 Reconstruction, in which part of antrum and pylorus is left along with the duodenum.* Characterized by excess secretion of Gastrin from retained antrum exposed to alkaline medium in Duodenum an...
Surgery
Stomach & Duodenum
8660b6e4-7672-4c69-acd5-44b024164f86
Most common adverse effect of colchicine -
Diarrhoea
Peptic ulcer
Dyspepsia
Pulmonary fibrosis
0a
single
Ans. is 'a' i.e., diarrhoea "Nausea, vomiting, diarrhea and abdominal pain are the most common untoward effects of colchicine". - Goodman & Gilman
Pharmacology
null
ffcefe74-7680-4979-a5f6-f232fafb96af
Soft tick transmits:
Relapsing fever
KFD
Tularemia
Indian tick typhus
0a
single
Among the given options soft tick transmits relapsing fever while the KFD, tularemia and Indian tick typhus are transmitted by hard ticks. Ref: Park Textbook of Preventive and Social Medicine, 19th Edition, Pages 622-23, 634-35
Social & Preventive Medicine
null
87dc3638-9565-42ab-b9d2-d68833f23c1d
Diagnosis of ABO incompatiability can be from all of the following except?
Sweat
Saliva
Semen
CSF
3d
multi
Ans (d) CSF Ref Reddy , p 378 ABO group specific substances are found in high concentration in saliva, semen, vaginal secretion and gastric juice while in low concentration in sweat, tears and urine, so it is possible to determine blood group from an examination of these secretions. So for this question it can be said ...
Microbiology
null
c3c9e2ee-ee5c-41af-b173-9b853ae83965
A chronic alcoholic has an elevated serum alpha fetoprotein levels. Which of the following neoplasms is most likely -
Prostatic adenocarcinoma
Multiple myeloma
Hepatocellular carcinoma
Glioblastoma multiforme
2c
single
Elevated levels of serum α-fetoprotein are found in 50 to 75% of patients with HCC. False-positive results are encountered with yolk-sac tumors and many non-neoplastic conditions, including cirrhosis, massive liver necrosis, chronic hepatitis, normal pregnancy, fetal distress or death, and fetal neural tube defects suc...
Pathology
null
3335cb92-8edf-474b-9068-f795f15502f4
Eaton agent is -
Chlamydia
Mycoplasma pneumoniae
Klebsiella
H. influenzae
1b
single
Ans. is 'b' i.e., Mycoplasma pneumoniae
Microbiology
null
bb8f19f1-e23d-414c-af4b-d2745226241e
True about primary angle closure glaucoma –a) More common in femalesb) Shallow anterior chamber is a risk factorc) Deep anterior chamber is a risk factord) Shorter diameter of cornea is a predisposing factore) Common in myopes
acd
abd
abc
ab
1b
multi
PACG is more common in females. Shallow anterior chamber, small diameter of cornea and hypermetropic eye (not myopia) are risk factors.
Ophthalmology
null
c8c24b36-0891-45b2-a37d-a227252c6245
Injection abscesses due to use of contaminated vaccines occurs in infections caused by
M. kansasii
M. ulcerans
M. chelonae
M. smegmatis
2c
single
null
Microbiology
null
ff6ef05e-6e0c-45eb-af3d-844aef052495
Black foot disease is seen in?
Arsenic
Lead
Mercury
Thallium
0a
multi
null
Forensic Medicine
null
b8231b4b-d996-46d8-a47d-a8574727044a
Typically bilateral inferior subluxations of the lens is seen in –
Marfan's syndrome
Homocystinuria
Hyperinsulinemia
Ocular trauma
1b
multi
In Homocystinuria there is inferomedial (inferonasal) dislocation of lens.
Ophthalmology
null