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135
d6dc62bb-1a9b-47dc-a657-864be5930829
Earliest method of diagnosing pituitary tumour
CT scan
Visual field chaing
Visual evoked potential
X-ray skull
0a
single
Ans. is 'a' i.e., CT Scan
Surgery
null
2b086f5a-597e-4ae8-8be5-7b4df1771edd
Shortest incubation period in malaria -
P. vivax
P. falciparum
P. malariae
P. ovale
1b
single
null
Microbiology
null
600661bd-31a5-45c5-ab76-74bc29784fce
Maintenance of oral health is best achieved by
hard bristle tooth brush
Mouth wash
A soft bristle brush and tooth paste
A soft bristle brush and dental floss
3d
single
null
Dental
null
3cfcc255-6dc0-4392-89ca-cc06ed4872ef
FAST -
CT
USG
MRI
X-ray
1b
single
Ans. is 'b' i.e., USG o FAST stands for focused assessment with sonography for trauma,o FAST is the preferred triage method for determining the presence of hemoperitoneum in blunt trauma patients or cardiac tamponade in blunt and penetrating trauma patients,o The four areas scanned in FASTSubxiphoid areaRt. upper quadr...
Surgery
Initial Assessment
8965e8bc-986a-4dad-8af2-0b694be00e98
In gingival index score 2 means:
Bleeding on slight provocation
Spontaneous bleeding
Colour change in gingiva
No change in gingiva
0a
single
null
Dental
null
f112a4ea-ae86-4346-a5ad-e70d0b237f63
Which of the following vitamins can be used for treatment of hypercholesterolemia?
Thiamine
Biotin
Pyridoxine
Nicotinic acid
3d
single
ANTI-DYSLIPIDEMIC AGENTS Group Mechanism Drugs Special points Statins HMG CoA reductase inhibition Atorvastatin, Rosuvastatin Max LDL lowering capacity Fibrates Stimulation of PPAR-alpha Clofibrate Fenofibrate Gemfibrozil Max TG lowering capacity Bile acid sequestrants Binds bile acids in GIT Cholestyramine, Colestipol...
Pharmacology
Hematology and CVS
4dfd0a4d-02a5-4939-95d8-dde87e74e0d9
True about EMLA:
Can be used for intubation
Mixture of local anesthesia
Faster acting
All
1b
multi
B i.e. Mixture of local anesthesia - Procaine, Mepivacaine & BupivacaineQ (Provide me BUM) are never used topically. - EMLA is eutectic mixture of local anesthetics (2.5% lidocaine & 2.5% prilocaine)Q commonly used to make venepuncture painless especially in children.
Anaesthesia
null
c39803d4-d603-4cc3-9278-dc84abcc514e
Dose of Carbetocin for post paum hemorrhage
100 microgram intramuscular
50 microorgam Inravenous
150 microgram intravenous
200 microgram intramuscular
0a
single
Refer Goodman Gilman 12th/1851 Carbetocin is along acting Oxytocin that us useful to prevent post pay hemorrhage given intramuscularly or intravenously in a dose of 100 microorgam
Pharmacology
Endocrinology
fd138f34-a7e3-4ba2-9b5d-c7b705398cb8
Schatzki's ring is present in -
Upper end of esophagus
Mid-esophagus
Squamocolumnar junction in esophagus
Fundus of stomach
2c
single
Ans. is 'c' i.e., Squamocolumnar junction in esophagus Schatzki's ringo It occurs at the junction of squamous and columnar epithelium at the lower end of oesophagus and has also been called lower oesophageal ring.o Usually seen in patients above 50 years of age.o Cause is unknown.o Symptomatic patients complain of inte...
ENT
Oesophagus
f9675475-3cf1-4701-bbe8-029304841b99
All are true about ulnar nerve except:
Root value C8TI
Pass through cubital tunnel
Supply flexor digitorum superficialis
Supply flexor carpi ulnaris
2c
multi
Ans. c. Supply flexor digitorum superficialis Nerve course:Root value of ulnar nerve is C7, C8 6 T1.Ulnar nerve (C8, T1) arises from the medial cord of the brachial plexus & descends in the interval b/w the axillary aery & veinAt elbow, ulnar nerve passes behind the medial epicondyleThe cubital tunnel is a channel whic...
Anatomy
null
6e468d73-06d0-49d0-9070-8f93c65443f3
True about the location of parotid gland:
Between the ramus of the mandible and buccinator.
Between the ramus of the mandible and sternocleidomastoid.
Between the ramus of the mandible and masseter.
Between the ramus of the mandible and medial pterygoid.
1b
multi
null
Anatomy
null
a15f2fd1-145c-4c4e-92af-a4a68ab46987
Collagen is found in following, except?
Ligament
Tendon
Fibroblasts
Aponeurosis
2c
multi
Fibroblasts
Anatomy
null
82098196-b819-4084-8ed0-c62755ad3c51
True about blood pressure measurement is all/except
Cuff width should be 40% of arm circumference
Diastolic blood pressure is indicated by fouh Korotkoff sound
Small cuff measures spuriously elevated Diastolic blood pressure
Monkenberg sclerosis causes pseudohypeension
1b
multi
Diastolic blood pressure is indicated by fouh Korotkoff sound According to American Hea Association- onset of phase I Korotkoff s sound corresponds to systolic pressure and the disappearance of sounds (phase V) corresponds to diastolic pressure . More points about measuring blood pressure The standard technique for blo...
Physiology
null
8fa90ddc-90fa-4d26-ad9f-97b49c021f58
In status epilepticus, drug of choice is:
I/V diazepam
I/M diazepam
Oral clonazepam
I/M phenytoin
0a
single
A i.e. IV diazepam Status epilepticus is said to occur when seizures lasts beyond 30 minutes or seizures are repetitive, prolonged & the patient remains unconscious in between the seizures. The drug of choice is /V Lorazepam (Benzodiazipine)Q 0.1 mg/kg at rate of 2 mg/min. Pharmacologic treatment of generalized tonic-c...
Anaesthesia
null
719db82c-ebb3-4933-aa2f-2caf3a7a3546
When activated by b-adrenergic receptors, the G protein:
Activates phospholipase C
Activates adenylate cyclase
Activates protein kinase C
Conves guanosine diphosphate (GDP) to guanosine triphosphate (GTP)
1b
single
When norepinephrine binds to a beta-adrenergic receptor, it activates a G protein (i.e., a guanosine triphosphate (GTP) binding protein), which, in turn, activates adenylate cyclase. Adenylate cyclase catalyzes the formation of cyclic adenosine 3',5'-monophosphate (cAMP), which activates a variety of kinases. One of th...
Pharmacology
null
a4c14d59-53a9-417d-a451-433bf93a0a64
Generator area in a nerve cell is
Cell body
Initial segment
Axon
Dendrites
1b
single
The first poion of the axon is called the initial segment. The Initial segment in spinal motor neurons, the initial node of Ranvier in cutaneous sensory neurons is a site where propagated action potentials are generated.(Ref: Ganong's Review of Medical Physiology Twenty-Third Edition)
Physiology
Nervous system
1ae6a79f-961c-4a17-9331-cf34308bf201
Coronary blood flow is maximum during?
Isovolumetric contraction
Rapid ejection
Slow ejection
Isovolumetric relaxation
3d
single
ANSWER: (D) I so volumetric relaxationREF: Ganongs 22nd ed page 621CORONARY BLOOD FLOW:Coronary blood flow, like blood flow in other vessels, is dependent on a pressure gradient, principally driven by mean arterial pressure. However, because aortic pressure can vary widely and because the heart beats continuously, the ...
Physiology
Circulation: Coronary Circulation and Ischemic Heart Disease
4d97be90-aaf4-4eec-b626-117d8514e954
Ideal age for repair of vaginal agenesis is :
6 months
3 years
At pubey
Before marriage
3d
single
Before marriage Repair of vaginal agenesis (seen in testicular feminizaton syndrome and Rokitansky-Kuster Hauser syndrome) is done by vaginoplasty. Vaginoplasty should only be performed when the girl is just married or about to be married. Techniques : 1. Frank dilatation (Non surgical method). 2. Construction of aific...
Gynaecology & Obstetrics
null
c3234b3f-3633-4778-8acb-798beaf900d8
Which type of articulators permit horizontal as well as vertical motion, but do not orient the motion to the TMJ via facebow transfer?
Class I
Class II
Class III
Class IV
1b
single
Class II articulator: Articulator which permit horizontal and vertical motion but they do not orient the movement to TMJ with a facebow. Three types.
Dental
null
5b6e2440-5f9a-4583-80cc-ff7cd72fdb71
Sensory supply of vocal cord ?
Internal laryngeal nerve
Recurrent laryngeal nerve
Superior laryngeal nerve
All of the above
3d
multi
Ans. is 'd' i.e., All of the above Above the vocal cords the sensory innervation of larynx is internal laryngeal nerve (a branch of superior laryngeal nerve). Below vocal cords it is by way of branches of recurrent laryngeal nerve. The vocal cord itself receives dual innervation from both nerves"_en.wikipedia Nerve sup...
ENT
null
6879ce4b-a870-4c52-bdcc-36ca2991b87e
Which is the following is not inherited as X-linked recessive: March 2005, September 2012, March 2013
G-6-PD deficiency
Duchenne muscular dystrophy
Cystic fibrosis
Hemophilia
2c
single
Ans. C: Cystic fibrosis X-linked diseases usually occur in males. Males have only one X chromosome. A single recessive gene on that X chromosome will cause the disease. The Y chromosome is the other half of the XY gene pair in the male. However, the Y chromosome doesn't contain most of the genes of the X chromosome. It...
Pathology
null
44dd5d46-5799-4119-bb66-2179604c29f0
The tensile strength of the wound stas and increases after
Immediately after suturing
3-4 days
7-10 days
1 month
1b
single
Wounds do not begin to gain tensile strength from collagen until 5 - 7 days. Wound achieves around 20 % by 3 weeks, and around 60 % by four months. Scar tissue continues to remodel for at least 6 - 12 months after an injury.
Anatomy
G.I.T
83e24a4f-109a-43f6-9d53-6c3d437d4c58
Characteristic of obstructive pulmonary disease are all except: March 2007
Reduced FEV1
Reduced diffusion capacity
Reduced residual volume
Reduced mid expiratory flow rate
2c
multi
Ans. C: Reduced residual volume The diagnosis of COPD is confirmed by spirometry. Spirometry measures the forced expiratory volume in one second (FEV1) which is the greatest volume of air that can be breathed out in the first second of a large breath. Spirometry also measures the forced vital capacity (FVC) which is th...
Medicine
null
ca1850b8-32b5-4ee3-a803-a4f826a4d926
Which among the following is a true statement about Thymosin?
A Pituitary hormone that regulates thymic development
A Glycoprotein that confers passive immunity to non sensitized hosts
An antiserum against thymocytes
A thymic hormone that induces maturation of pre-T cells
3d
multi
Thymosin is a thymic hormone that regulates pre-T cell development. It is not released from the pituitary. Antithymocyte antibodies are not thymosin but are useful in transplantation rejection therapy. Lymphokines are released from T cells, but thymosin is a thymic hormone, not a lymphokine. Ref: Kipps T.J. (2010). Cha...
Physiology
null
31ceebd6-97f7-4158-8ebd-bc86663b7bed
Which of the following malignant disease of children has the best prognosis?
Wilm's tumor
Neuroblastoma
Rhabdomyosarcoma
Primitive neuroectodermal tumor
0a
single
Ans. is 'a' i.e. Wilms' tumour Ref: C.P.D.T 16th/e page 807-809, 811 Schwartz Surgery page 1748, 1749, 1747Prognosis depends most importantly upon staging but there are multiple factors affecting the prognosisAfter going through the survival rates of these tumours and confirming our answer with a paediatric oncologist ...
Surgery
Renal Tumors
252ebf68-20e2-463d-9970-32106af5969a
Which of the following is true about fouh hea sound 'S4'
Can be heard by the unaided ear
Frequency is greater than 20 Hz
Heard during ventricular filling phase
Heard during ventricular ejection phase
2c
multi
4th hea sound cannot be heard even by a stethoscope since its frequency is below the audible limit (20 Hz). It is produced during last rapid filling of ventricles, which occurs due to atrial systole. Hence, it is also called "atrial sound". S1: Closure of A.V. valves (25-45 Hz) and S2: closure of semilunar valves (50 H...
Physiology
Cardiac Cycle
98ce8737-f7be-4a7c-9477-efe797bd0637
All are included in Amsler's criteria, EXCEPT:
Vaginal pH <4.5
Positive amine test
Clue cells> 20% of total vaginal epithelial cells
Homogenous thin discharge
0a
multi
Amsler's criteria used for the diagnosis of bacterial vaginosis is based on clinical & lab indicators: Vaginal pH >4.5, alkaline Positive amine test Clue cells> 20% of total vaginal epithelial cells Homogenous thin discharge Scanty / absent lactobacilli 3 out of 5 criteria suggests this diagnosis Ref: Sexually transmit...
Skin
null
bee794e9-b504-4d94-b565-20e45d8b2d4b
A 60 year old man presents with chest pain which last 6 hours and is diagnosed as acute myocardial infarction. Angiography showed involvement of anterior descending branch of left coronary artery The most probable site of infarct is-
Anterolateral wall
Posterior wall
Inferior wall
Septal
0a
multi
null
Medicine
null
e7941e6a-c6c8-4539-ac37-c6932a9b1d59
Patients with porphyria are highly sensitive to which wavelength :
290-320 nm
400-420 nm
320-400 nm
250-290 nm
1b
single
Porphyrin are excited by visible light with a wavelength between 400 and 410 nm and emit an intense red fluorescence. The released energy reacts with oxygen to produce free radicals and singlet oxygen that damages tissues Mc porphyria - porphyria cutaneatarda (if- Red urine - D/D - myoglobinuria )
Dental
JIPMER 2018
869a79f4-a9b6-4f4c-9ea6-4b9789db8ac3
Killian's dehisence is seen in:
Oropharynx
Nasophrynx
Cricopharynx
Vocal cords
2c
single
Ans. C Cricopharynx Ref. Scott Brown's lth/ed Vol 2 Chapter 155 p 2045; Dhingra 5th/ed p 253, 6th/ed p 238 Killian's Dehiscence (Fig. 8.6) it is an area of weakness between the two pas of inferior constrictor muscle-sub thyropharyngeus and cricopha-ryngeus A pulsion diveiculum of pharyngeal mucosa can emerge posteriorl...
ENT
null
48f8b172-a374-4d0d-ab0c-f902e7d33e8d
Chromosome-associated with bipolar disease -
Chromosome 16
Chromosome 13
Chromosome 18
Chromosome 11
2c
single
Chromosomes involved in bipolar disorder are chromosome 18, 21, and 22.
Psychiatry
null
0e242541-6548-43d7-819e-a50c52d42acb
Feature that differentiates true from aificial bruise
Round shape, irregular margins
Irregular shape with regular margins
Swelling of surrounding area
Erythema of surrounding areas
1b
multi
contusion: not well defined, diffuse, and irregular margins Aificial bruise: well defined with regular margins. Ref: FORENSIC MEDICINE AND TOXICOLOGY DR PC IGNATIUS THIRD EDITION PAGE 120
Forensic Medicine
Mechanical injuries
9ffd6fd9-dcdb-4e1a-9968-53e84b62f3b5
Which one of the following elements is NOT added in small amount to be used as grain refiners?
Iridium
Ruthinium
Indium
Platinum
3d
multi
null
Dental
null
1c23e1f1-760e-48cc-93f7-1f717f894a0c
The prototype of type-H hypersensitivity reaction is?
Ahus reaction
SLE
Autoimmune hemolytic anemia
Contact dermatitis
2c
single
Ans. is 'c' i.e., Autoimmune hemolytic anemia
Microbiology
null
8b7d9930-955e-4bd8-baf4-c7cf266cb8c0
True statement about ductus Arteriosus is –
It undergoes anatomic closure within 24 hours of birth
Forms the ligamentum venosum in later life
It is induced to close by high levels ofprostaglandins
May cause a machinary murmur by its patency.
3d
multi
This question deals with the changes in blood circulation that occur at birth : Closure of Ductus arteriosus The closure occurs almost immediately after birth by contraction of its muscular wall, mediated by bradykinin. i.e. Physiological closure. Anatomic closure occurs by proliferation of intima, and may take fro...
Pediatrics
null
8c8a3862-bc83-4271-9a43-af79acd79b4d
A five year old child presents with ballooning of prepuce after micturation. Examination of penis reveals prepucial adhesions which the following the best treatment
Adhesiolysis & dilatation
Circumcision
Dorsal slit
Conservative management
1b
multi
The child is having congenital phimosis(inability to retract the prepuce over the glans) in which case the child has pinhole meatus and ballooning of prepuce on voiding. The best treatment is circumcision. Patients with phimosis are more prone for recurrent infection, smegma collection and carcinoma penis. Reference : ...
Surgery
Urology
526dc19c-99d2-4acc-994c-c1ae24eaf947
Torus aorticus involves:
Left atrium
Arch of aorta
Ascending aorta
Right atrium
3d
single
Ans. d (Right atrium). (Ref. Grey, Anatomy, 36th ed., 644)Torus aorticusAnterosuperior part of septal wall of right atrium bulges to some degree into the atrial cavity as torus aorticus. It is caused by proximity of right posterior aortic sinus and cusp.Torus auditoryThe postero-inferior wall of external meatus occasio...
Anatomy
Thorax
258609c2-6dfd-45f0-852f-d25665a6c0ec
Cavett test is used for detection of
Opiates
Alcohol
Barbiturates
Cocaine
1b
single
Test for alcohol : Cavett test Kozelka and thine test Alcohol dehydrogenase test Gas chromatography (Most specific)
Forensic Medicine
null
118da4b4-d2c1-4452-a6bd-cd749faacf0a
All are features of Meniere's disease except:
Hearing loss that fluctuates
Giddiness is provoked in certain head positions
Sense of pressure or fullness in the ear
Roaring tinnitus
1b
multi
Giddiness occurring in certain head positions such as bending forward to pick up an article or reaching for an article in the overhead shelf or turning one's position in the bed is a feature of benign paroxysmal positional vertigo (BPPV). The condition is due to free-floating particles (otoconia) in the endolymph of ve...
ENT
Ear
c4116d9c-9904-48a5-a95a-fa6b7958c547
The most common complication of immunosuppression is:
Malignancy
Graft rejection
Infection
Thrombocytopenia
2c
single
Ans. (c) InfectionRef: Bailey 26th edition, Page 1416* Bacterial infection is most common in 1st month and is most common in those who are critically ill before and after transplant.* Viral infection is most common in 6 months--Most common is CMV > HSV* BK virus is universal in childhood causes urinary infection* Pneum...
Surgery
Transplantation
ee52024a-4e71-4e0b-b1eb-ad1adb17cccd
'Time out' is useful in the treatment of:
Temper Tantrums
Pica
Anorexia nervosa
Nocturnal enuresis
0a
single
Time-out- behavioral modification that involves temporarily separating child from an environment where an unacceptable behavior has occurred. The goal is to remove that child from an enriched, enjoyable environment- lead to extinction of the offending behavior. Distraction and 'time-out' strategies are useful in treatm...
Pediatrics
Behavioral Disorders in Children
14465a03-0113-4b7f-85ef-d4befb6c36c0
The extended sickness benefit is given for:
309 days
409 days
365 days
490 days
0a
single
309 days
Social & Preventive Medicine
null
9f47ff08-59fc-4221-bfae-9a9fb12516ba
Which among the following is a killed vaccine
Japanese encephalitis
Measles
Influenza vaccine
Yellow fever
0a
single
Japanese encephalitis vaccine is a killed vaccine Killed vaccines are produced by growing virus or bacteria in a culture media and then inactivating them with heat or chemicals They are usually safe but less efficacious than live attenuated vaccines. Measles, yellow fever and influenza vaccines are live attenuated vacc...
Social & Preventive Medicine
Communicable diseases
8d23007b-3fb6-4d6b-9869-5179c1f82765
Undiagnosed or undetected ectopic pregnancy is a common cause of maternal death during the first trimester. Most valuable diagnostic test in a case of suspected ectopic pregnancy is:
Serial (3-hCG levels)
Transvaginal USG
Progesterone measurement
Culdocentesis
1b
single
Transvaginal ultrasonography (TVUS) has the advantage of earlier and better localization of the pregnancy, with less pelvic discomfo because the bladder is not painfully distended. The double-ring sign and the yolk sac must be identified to ensure that the pregnancy is intrauterine. When an intrauterine pregnancy is no...
Gynaecology & Obstetrics
null
a2ff4e81-b9d0-46ae-b1ed-b4f0ca013165
A 6 - year - old boy with lymphoreticular malignancy has come for a cycle of chemotherapy. Which of the following investigatins need to be done for next 4 hours to diagnose tumour lysis syndrome?
Urea, creatinine, chloride, Ca2+ and K+
Urea, creatinine, phosphate, Ca2+ and K+
Urea, creatinine, magnesium, Ca2+ and K+
Urea, creatinine, sodium and phosphate
1b
single
Tumour lysis syndrome (TLS) - -Uric acid, phosphate and potassium are released in large quantities from death of tumour cells. -Hyperuricemia can lead to impairment of renal function, which fuher exacerbates the metabolic abnormalities. -Hypocalcaemia is a consequence of acute hyperphosphatemia with subsequent precipit...
Pediatrics
JIPMER 2017
5c80072f-1a5c-45d1-8c4a-d23ea2b77c73
All true about CisATRACURIUM except-
It is pure Cis isomer of atracurium
It is more potent than atracurium
It is also causes histamine release like atracurium
Metabolism similar to atracurium
2c
multi
Cisatracurium is pure sis isomer of atracurium. It is more potent and has longer onset time than atracurium. Metabolism is similar to atracurium. It releases less histamine than atracurium. Cisatracurium does not cause histamine release unlike atracurium. Cisatracurium produces laudanosine but is about five times lesse...
Anaesthesia
Neuromuscular Blocker
918d8399-0646-488e-92b6-00feed6cd2de
Pre-renal azotemia is associated with one of the following characteristic feature -
Urinary Na+ < 10 mmol/L
Renal failure index > 1
Osmolality < 500
Urinary creatinine/P. creatinine ratio < 20
0a
single
null
Medicine
null
d1de0eb0-b99c-4e9b-9a45-37a999df00c1
Ejection fraction is about
25%
45%
55%
65%
3d
single
The ejection fraction, the percent of the end-diastolic ventricular volume that is ejected with each stroke, is about 65%. The ejection fraction is a valuable index of ventricular function.
Physiology
null
40961ae9-8d71-411c-b754-dd661236c8e0
Opaque white areas covering more than 25% but less than 50% of the tooth surface is given the Dean's score of:
1
2
3
4
1b
single
null
Dental
null
162825db-9bcc-4840-87f2-d66730a6dd5a
In a man lifting up a suitcase, posterior dislocation of glenohumeral joint is prevented by:
Deltoid
Latissimus dorsi
Coracobrachialis
Supra spinatous
2c
single
Ans. (c) CoracobrachialisRef : Gray's 41st ed./819-821* The coracobrachialis is an elongated muscle in the superomedial part of the arm. The coracobrachialis helps flex and adduct the arm and stabilize the glenohumeral joint.* With the deltoid and long head of the triceps, it serves as a shunt muscle, resisting downwar...
Anatomy
Back, Deltoid, and Scapular Region
c8e3cc5e-1333-4c46-89d1-6e72de52990b
Xerosis is seen in: September 2006
Vitamin A deficiency
Vitamin B deficiency
Vitamin C deficiency
Vitamin D deficiency
0a
single
Ans. A: Vitamin A deficiency
Ophthalmology
null
c845a938-de2d-4eed-80ab-ceb4fe57705f
What is the treatment of choice in duodenal ulcer without any complication of hemorrhage?
Highly selective vagotomy
Trunkal vagotomy
Proton pump inhibitors
None
2c
multi
Proton pump inhibitors like Omeprazole can produce relief in patients with duodenal ulcer. Perforation complicates duodenal ulcer about half as often as bleeding and most perforated ulcers are on the anterior surface of the duodenum. The patient population tends to be elderly (mean age 60-70), chronically, ill patients...
Surgery
null
739a6c60-0f20-4638-a2a5-abafeaeb4197
The maintenance dose of digoxin
0.25 mg/day
2.5 mg/day
25 mg/day
250 mg/day
0a
single
Slow digitalization: Here maintenance dose of Digoxin (average 0.25 mg/day) is given from the beginning. Full response takes 5-7 days to develop, but the procedure is much safer. In case an adequate response is not seen after I week, increase the dose to 0.375 and then to 0.5 mg after another week.Rapid oral digitaliza...
Microbiology
All India exam
d8e2ace6-84a4-462e-a7b5-6e6dd4d347f2
Pentosuria is due to defect in which pathway?
Glycolysis
Polyol pathway
Uronic acid pathway
Kreb's cycel
2c
single
Essential Pentosuria i. It is one of the members of the Garrod&;s tetrad. The incidence is 1 in 2,500 bihs. ii.It is an inborn error of metabolism, due to defect in glucuronic acid pathway of glucose. In the pathway, L-xylulose is conveed to D-xylulose by two enzymes, xylitol dehydrogenase and xylulose reductase absenc...
Biochemistry
Metabolism of carbohydrate
ced643ca-14d5-495c-97f6-64feea76b3a9
Which of the following milestone is achieved at 36 months -
Drawing a rectangle
Building a tower of 20 cubes
Riding a tricycle
Skipping
2c
single
Ans. is 'c' i.e., Riding a tricycle Milestones seen at 36 monthso Rides tricycleo Stands momentarily on one footo Draws a circle.o Can dress or undress himself completely and succesfully buckles his shoeso Builds tower of 10 cubeso Knows his gender and ageo Repeats a sentence of 6 syllableso Has a vocabulary of 250 wor...
Pediatrics
Developmental-Behavioral Screening and Surveillance
c41c21ed-f5b9-4a62-ac53-e6ae55e8dc4a
Which of the following ovarian tumor is most prone to undergo torsion during pregnancy?
Serous cystadenoma
Mucinous cystadenoma
Dermoid cyst
Theca lutein cyst
2c
single
Ans. is c, i.e. Dermoid cystRef. Novak 14/e, p 510; Dutta Obs. 6/e, p 310"Incidence of dermoid cyst increases two times in pregnancy and it becomes the most commonly diagnosed ovarian tumour during pregnancy." --Dutta Obs. 7/e, p 310"A benign cystic teratoma is the most common neoplasm to undergo torsion." --Novak 14/e...
Gynaecology & Obstetrics
Gynaecological Disorders in Obs.
c428c414-c0e1-4f26-929f-3cdd9e07113e
Thermo-stability in DNA is contributed mostly by:
A=T
GEC
Molecular base
Parallel arrangement
1b
multi
B i.e. G CThermostability in DNA is constributed mostly by C GQ because there are 3 Hydrogen bonds between C & GQ. G C bonds are much more resistant to denaturation or melting than A= T rich region (2 Hydrogen bonds)
Biochemistry
null
7db5693e-a3c3-445d-b52c-de6681717f5f
Direct action of radiation is the dominant process for
X-rays
Neutrons and alpha paicles
Electrons
Gamma rays
1b
single
Ionizing radiation acts by two methods: Direct and IndirectDirect action is radiation directly causing DNA damage; example: neutrons and alpha paiclesIndirect action is radiation causing free radical production which acts on DNA; example: photons and gamma raysReference: Khan Physics of Radiation therapy; 5th edition
Radiology
Radiotherapy
686e564a-130d-4069-ac90-c202fae223c2
Chesser Moir technique is used in :
VVF
Stress incontinence
Urethrocoete
Enterocoele
0a
single
VVF Chassar Moir technique is used for repair of vesico vaginal fistula. Few named surgical procedures In Few named surgical procedures In Procedure Indication Marshall -- Marchetti Krant surgery Marshall and Bonneys test Boari operation Manchester operation Fothergill operation Strassmam Metroplasty Jones Metroplasty ...
Gynaecology & Obstetrics
null
6e398623-3cce-45a5-9c55-ea82300323cd
The storage triacylglycerol are hydrolysed by:
Pancreatic lipase
Lipoprotein lipase
Lysosomal lipase
Hormone sensitive lipase
3d
single
Ans. D. Hormone sensitive lipase(Ref: Harper 31/e page 244)Pancreatic lipase to hydrolyse dietary TGsLipoprotein lipase to hydrolyse TGs in lipoprotein in the bloodLysosomal hydrolase to act on TGs in lysosomes
Biochemistry
Lipids
a74001e4-a3c7-4938-bb01-de60474c782c
Shelf life of platelets in blood bank is?
5 days
8 days
10 days
21 days
0a
single
Platelets are stored in plasma or in additive solution up to 5-7 days at 20-24degC and under permanent motion.
Medicine
Platelet & Coagulation disorders
e36d3d6f-7b23-4aca-84d1-02e571686d22
All the following pathogenic bacteria fulfill Koch's postulates, except -
Treponema pallidum
Yersinia pestis
Bacillus anthracis
Helicobacter pylori
0a
multi
Ans. is 'a' i.e., Treponema pallidum
Microbiology
null
d46bfb42-0e5b-4701-999a-dc4f91c47d39
Which is the most common location of carcinoid tumor ?
Bronchus
Ileum
Rectum
Colon
0a
single
Location of carcinoid tumors: Bronchus 27.9% , Ileum 14.9%, Rectum 13.6 %, colon 8.6 %. So Ileum comes next to bronchus and first in GI tract. Reference: Harrisons Principles of Internal Medicine, 18th Edition, Page 3058, Table 350-3
Medicine
null
0aa3ac17-73ac-4d47-8b19-d9bb50d510f8
Limits of confidence of a hypothesis determined by?
Power factor
Level of significance
1-power factor
1 -lev el of significance
3d
single
Ans. is 'd' i.e., 1-Level of significance First read about these different terms : ? Confidence interval It is the interval within which a parameter value is expected to lie with ceain confidence levels, as could be revealed by repeated samples. o It is the interval (range) around the mean of population in which the me...
Social & Preventive Medicine
null
aeef7ff7-75b0-4d54-87b6-da76a05c545f
A patient suffering from Zollinger- Ellison syndrome would be expected to have:
Excessive acid reflux into the esophagus, resulting in esophagitis
Excessive secretion of CCK, causing continuous contraction of the gallbladder
A gastrin-secreting tumor of the pancreas, causing excessive stomach acid secretion and peptic ulcers
Low plasma lipid levels, due to failure of the liver to secrete VLDLs
2c
multi
Ans. C. A gastrin-secreting tumor of the pancreas, causing excessive stomach acid secretion and peptic ulcersExcessive production of gastrin results in acid hypersecretion and peptic ulcer disease. Patients with Zollinger-Ellison syndrome do not suffer from excessive acid reflux, excessive secretion of CCK, failure of ...
Physiology
G.I.T.
5f0ed002-ca87-44b4-9418-d2ff25ae0ca8
Most common ALL subtype:
Pre B cell
Pre T cell
T cell
B cell
0a
multi
Ans. (a) Pre B cellRef: Robbin's pathology 9th ed. /590-93* Most common subtype of ALL is LI according to older classification and Pre B cell variety by the latest WHO classification.* The recent WHO International panel on ALL recommends that the FAB classification be abandoned, since the morphological classification h...
Pathology
Lukemia
371e5d5b-6b47-4af7-b86d-757851bb0d54
Crude birth rate – Not true is
It is actually a ratio not a rate
It is a measure of fertility
It is independent of age of population
Numerator does not include still births
0a
multi
Crude birth rate (CBR) : is the natality or childbirths per 1,000 people per year. CBR (World) : 19.9 per 1000 population (Max 15 Niger ; Min 7 Monaco) . CBR (india) : 21.8 per 1000 population . Is a measure of fertility. CRUDE means it includes all causes and all ages - It is independent of age of population.
Social & Preventive Medicine
null
dd571745-7c8a-4f30-a25d-dce43aaa56f5
A 28-year-old previously healthy woman arrives in the emergency room complaining of 24 h of anorexia and nausea and lower abdominal pain that is more intense in the right lower quadrant than elsewhere. On examination she has peritoneal signs of the right lower quadrant and a rectal temperature of 38.38degC (101.8degF)....
Cecal diverticula are acquired disorders
Cecal diverticula are usually multiple
Cecal diverticula are mucosal herniations through the muscularis propria
Diverticulectomy, closure of the cecal defect, and appendectomy may be indicated
3d
multi
Cecal diverticula must be differentiated from the more common variety of diverticula that are usually found in the left colon. Cecal diverticula are thought to be a congenital entity. The cecal diverticulum is often solitary and involves all layers of the bowel wall; therefore, cecal diverticula are true diverticula. D...
Surgery
Liver
78057260-857c-478a-9027-bc6c60bf6163
A 30 years old male presented with silvery scales on elbow and knee, that bleed on removal. The probable diagnosis is –
Pityriasis
Seborrhoeic dermatitis
Psoriasis
Secondary syphilis
2c
single
Morphology of papules/plaques in various papulosquamotas disorders Psoriasis - Erythematous papules and plaques on extensors (elbow & knee Lichen planus - Violaceous papules with Wickham's striae an flexural surface Pityriasis rosea - Annular plaques on Trunk Seborrheic dermatitis - Yellowish, follicular papules on sc...
Dental
null
8bb8e5d7-9594-41bc-8854-5e4e37ef38a8
Fluroide ions act by inhibiting -
Enolase
Hexokinase
Cytochrome oxidase
Carbonic anydrase
0a
single
A i.e. Enolase
Biochemistry
null
b0311c61-f13e-42a6-9d86-9089157bcc14
Following trauma, which hormone is not released-
Thyroxine
Glucagon
ADH
GH
0a
single
null
Surgery
null
24983e8c-2deb-4313-a12b-3607043ef1df
Not an experimental study
RCT
Ecological study
Pre - post clinical study
Meta - Analysis
1b
single
null
Social & Preventive Medicine
null
e685f32f-17f9-4ee6-a9c8-058054cfdaf0
Which of the following agents is useful for the oral treatment ofboth pituitary as well as renal diabetes insipidus?
Vasopressin
Hydrochlohiazide
Chlorpropamide
Carbamazepine
1b
multi
(Ref: KDT 6/e p577, 578) Thiazides are useful in the treatment of central as well as nephrogenic DI. Vasopressin, chlorpropamide and carbamazepine are useful only in central DI.
Anatomy
Other topics and Adverse effects
2813db08-5b53-42d8-ade7-71490e3e8ce8
Which of the following protein binds to free heme?
Ceruloplasmin
Haptoglobin
Hemopexin
Hemosiderin
2c
single
Ans: c) Hemopexin Option analysis: Binding protein Ceruloplasmin is a copper containing protein Haptoglobin Free Haemoglobin Hemosiderin Denatured ferritin Hemopexin is a b1-globulin that binds free heme
Biochemistry
Vitamins and Minerals
1d1c4bc1-e356-402c-8378-5aacb22eda4b
Pregnant patient comes at 34 weeks gestation with leaking. which investigation can be done for diagnosing the leak?
Speculum examination
USG
Non stress test
3 swab test
0a
single
Speculum Examination- Done taking aseptic precautions to inspect the liquor escaping out through the cervix. During sterile speculum examination,ruptured membranes are diagnosed if Amniotic fluid pools in the posterior fornix or clear fluid flows from cervical canal
Gynaecology & Obstetrics
JIPMER 2017
84b19255-3121-471c-ad86-c9ae99b02bf1
mood stabilizer used in the tretament of rapid cycling
vaproate
lithium
carbamezepine
lamotrigine
0a
single
Lamotrigine is a mood stabilizer which works best in BIPOLAR DEPRESSION Lithium is a mood stabilizer which works best in BIPOLAR MANIA valproate is a mood stabilizer which works best in RAPID CYCLING ref. kaplon and sadock, synopsis of psychiatry, 11 thedition, pg no.935
Anatomy
Pharmacotherapy in psychiatry
3f665570-2453-4aad-8bb6-6d21b13efe6b
The protective value of vaccine is 95%. It means
All those vaccinated are protected
5 among 100 have the probability of getting infected after vaccination
Among those vaccinated, 95% persons are not susceptible to the injections
95% of persons do not get the disease, where as 5% get the disease
1b
multi
Vaccine is an immuno-biological substance designed to produce specific protection against a given disease It stimulates the production of protective antibody and other immune mechanisms Vaccines can be prepared from live modified organisms, inactivated or killed organisms, extracted cellular fractions, toxoids or combi...
Social & Preventive Medicine
null
e99d970a-b834-47eb-ac08-d4b474787234
Commonest complication following haemorrhoidectomy is -
Hemorrhage
Infection
Facal impaction
Urinary Retention
3d
single
null
Surgery
null
5f627e2f-f0af-40e7-a319-b756b12be2d0
Quellung's reaction is seen in all except:
Strep pneumoniae
Neisseria gonorrhoeae
Hemophilus influenza
Neisseria meningitides
3d
multi
Ans. D. Neisseria meningitidesQuellung reaction is capsular swelling seen in capsulated bacteria. N. gonorrhoeae is not capsulated.
Microbiology
Bacteria
3c7964b4-3813-4fe6-bb40-f8ec9265b90a
False statement about TX A2 is
It is formed in platelets
It is formed from PGG2/h2
It is having platelet anti aggregatory reactivity
Asprin can inhibit its production
2c
multi
TX A2 is produced inside the platelets with the help of TX A2 synthetase It is formed from cyclic Endo peroxidase(PGG2/H2) with the help of an enzyme, cyclooxygenase Aspirin inhibit its production by reversible inhibition of cyclooxygenase enzyme TX A2 causes aggregation of platelets, therefore is prothrombotic Refer k...
Pharmacology
Autacoids
7287324b-5568-4f43-95da-59fad2919b0f
Drug of choice for strongyloides stercoralis?
Mebendazole
Albendazole
Ivermectin
Levamisole
2c
single
Ans. C. IvermectinRef: K.D,T, Thle p, 850i Katzung 13th/e p. 909; Satoskar Pharma 24'e p. 816; Rang and Dale |th/e p. 573Strongyloid - IvermectinAnaerobes - MetronidazoleAtypical Pneumonia (mycoplasma) - ErythromycinCholera - DoxycyclineStaphylococci - PenicillinVRSA - LinezolidP. Carinii (jiroveci) - CotrimoxazolePseu...
Pharmacology
null
4cc0d4b6-741d-4386-9a27-cd47ad53f74f
PHYSICAL QUALITY OF LIFE INDEX (PQLI) includes:
Infant mortality, Life expectancy and Literacy
Maternal mortality, Life expectancy and Literacy.
Disability rate, Pregnancy rate and GNP
Longevity, Knowledge and Income
0a
single
Ans. a (Infant mortality, Life expectancy and Literacy). (Ref Park PSM 22nd/ pg. 16)INDEXPHYSICAL QUALITY OF LIFE INDEX (PQLI)Consist of# Infant mortality,# Life expectancy at age one, and# Literacy.National and international comparison can be done.Kerala has highest PQLI.KUPUSWAMY INDEXKupuswamy index of social classi...
Social & Preventive Medicine
Concept of Health and Disease
cb821836-54fe-4c5f-8008-bfb167dcebc8
A 26 years old primigravida at 30 weeks of gestation on clinical examination, has blood pressure values of 142/100 mm Hg. 150/94 mmHg and 150/100 at 6 hours intervals. The next line of management is:
Add captopril
Add atenolol
Add methyldopa
No medical management is necessary at present
2c
single
Ans. is c, i.e. Add methyldopaIn this case although patient has mild elevated BP but her BP is continuously increasing which means she needs antihypertensive. The antihypertensive which can be used in pregnancy is Methyldopa.
Gynaecology & Obstetrics
Miscellaneous (Obs)
7fdfe0d6-8fa7-4002-a0ce-5ba23f45374f
Which of the following can be used as tumor marker in pancreatic carcinoma?
CA-125
CA 27-29
CA 19-9
CA 15-3
2c
single
CA 19-9 is a tumor marker for pancreatic as well as colon cancers.
Pathology
null
42893522-81c6-4195-bc5d-bfc0c3a8600e
Incubation period for diptheria and salmonella is
1-2 days and 20-40 days
2-6 days and 7-21 days
2-6 days and 10-14 days
1-2 days and 10-14 days
2c
single
Diphtheria Causative agent : Corynebacterium diphtheriae, a gran positive non-motile organism Diphtheria is an endemic disease in India Source of Infection Carriers are more impoant as source of infection: 95% of total disease transmission Nasal carriers are more dangerous than throat carriers Incidence of carriers in ...
Social & Preventive Medicine
Communicable diseases
0527b1e1-350e-480e-9857-83e3edf8fdcb
What would you advise a mother who has an allergy to protein but still wants to breastfeed?
Assure her that breastfeeding would not pass on the allergy to the infant
Advise her to consult her primary health care provider regarding this issue
Advise her to use formula milk instead to avoid allergies.
Let her alternate between breast milk and formula milk to reduce chances of acquiring the allergen.
0a
multi
A: Breast milk does not contain protein unlike cow’s milk, so it is safe to let the mother breastfeed the infant. B: The nurse should inform the mother of the benefits of breastfeeding and should not simply hand over the responsibility to the physician. C: Formula milk contains cow’s milk protein which could trigger an...
Surgery
null
73f93ccf-8777-4f82-ab69-6f5895b910f1
Fluoroacetate blocks the Krebs cycle by inhibiting the following enzyme
Citrate synthase
Aconitase
a-KG dehydrogenase
Succinate dehydrogenase
1b
single
The poison fluoroacetate is found in some of the plants, and their consumption can be fatal to grazing animals. Some fluorinated compounds used as anticancer agents and industrial chemicals (including pesticides) are metabolized to fluoroacetate. It is toxic because fluoroacetyl-CoA condenses with oxaloacetate to form ...
Biochemistry
Metabolism of carbohydrate
1185b0be-394a-4882-8882-97029b40d379
An organism not invading intact cornea-
Gonococci
C. diphtheriae
Meningococci
Pseudomonas
3d
single
Following three pathogens can invade the intact corneal epithelium and produce ulceration: Neisseria gonorrhoea, corynebacterium diphtheriae and Neisseria meningitidis.
Ophthalmology
null
c8940149-a8f3-4c33-935d-8e857033858f
True of case control studies
It proceeds from cause to effect
Odds ratio can be calculated
Incidence can be calculated
Needs many patients
1b
multi
<p>case control studies usually known as retrospective studies.are those which proceeds from efect to cause .it mainly involves two study populations cases and controls.they are basically comparison studies from which the"odds ratio" can be calculated.focus is on a health problem that has already occurred.not much pati...
Social & Preventive Medicine
Epidemiology
981e2d0b-f9f2-4fc1-8882-90aeaed67069
Which of the following adaptations will be apt to increase the work capacity at high altitude?
Increasing workload, decreasing duration of exercise
Increasing workload, increasing duration of exercise
Decreasing workload, increasing duration of exercise
Decreasing workload, decreasing duration of exercise
2c
single
Exercise increases oxygen requirements, which must now be met in the face of this decreased oxygen. Increase workload, will increase sever O2 demand, which cannot be met at high altitude due to low paial pressure of oxygen, fuhermore it can precipitate pulmonary edema. But decrease workload and increase duration, will ...
Physiology
Respiratory System Pa 1
15c1c1bf-741c-4ac7-9368-12001f1dfb2d
All of the following are true about Helicobacter pylori except:
About 50% of world population affected
85% of population is affected, in some developing countries
All children in developing countries have immunity by five years of age
Infection is common in low socio-economic status
2c
multi
Ans. is 'c' i.e., All children in developing countries have immunity by five years of age(Ref: Harrison, 16th/e, p. 886,19th/e, p. 1038; Ananthanarayan, 9th/e, p. 400)* Duodenal ulcer (80%) and Gastric ulcer (60%) are associated with H. pylori.* Gastric adenocarcinoma, gastric MALT lymphoma, Autoimmune gastritis, Hyper...
Microbiology
Bacteria
71893543-2585-4ff0-a8ca-812672965a99
Laryngeal prominence is formed by-
Cricoid cartilage
Hyoid bone
Anterior margin of thyroid
Angle of the thyroid cartilage
3d
single
The lower part of anterior borders of right and left laminae of thyroid fuse and form a median projection called laryngeal prominence.
Anatomy
null
68f53ada-5edb-44d9-b0b2-49fdb764b4a4
A 35 year old man who recently traveled to a third world country develops chronic, severe dysentery. Colonoscopy demonstrates ulceration of the cecum, and a cecal biopsy reveals 15-to-40 micron amoebae with ingested erythrocytes and small nuclei with distinctive tiny central karyosomes. Which of the following organisms...
Acanthamoeba sp
Balantidium coli
Entamoeba histolytica
Giardia lamblia
2c
multi
Entamoeba histolytica is the usual cause of intestinal amebiasis, and has the microscopic features described in the question stem. A paicularly helpful (but not always present) feature of this organism is the presence of ingested red blood cells within the amoebae. These amoebae cause flask-shaped ulceration of the int...
Microbiology
null
143ed582-f790-463b-ae8b-f637295169b9
Strongest oxygen radical amongst the following is
O2-
OH-
H2O2
HCIO
1b
single
Reactive Oxygen Species (ROS) radicals like the hydroxyl radical . It is the most reactive of them all; note how it differs from the hydroxyl ion . the superoxide anion which is both ion and radical
Biochemistry
Respiratory chain
638e198c-897d-4eb5-93df-6a9593fdda24
Which of the following causes minimal Poo hepatic compromise
Non selective shunts
TIPSS
Distal splenorenal shunt
Sclerotherapy
3d
single
Sclerotherapy is used in esophageal varices Endoscopic sclerotherapy controls active hemorrhage in 80% to 90% of patients. The combination of sclerotherapy with somatostatin, octreotide, and vapreotide has been repoed to be superior to sclerotherapy alone in terms of control of bleeding and reduction of treatment failu...
Anatomy
G.I.T
1b36be7e-1d22-4933-8d9f-568a57e2b390
Eye of tiger sign on MRI is seen in
Hallervorden spatz syndrome
Progressive supra nuclear palsy
Early onset levodopa - responsive Parkinsonism
All of the above
3d
multi
The eye of tiger sign refers to abnormal low T2 signal on MRI in the globus pallidus with a logitudinal stripe of high signal (due to gliosis and spongiosis).
Radiology
null
4cd8542b-50fa-4c8a-9916-96b6baaa0dbe
Minimal Ascites can be best detected by:
USG
Plain X-ray abdomen
MRI
CT scan
0a
single
A i.e. USG Earliest detection Investigation Ascites USGQ Pericardial effusion EchocardiographyQ Bronchiectasis CT-ScanQ Fetal life DopplerQ Pleural effusion IA lateral decubitus viewQ Pneumoperitonum Erect chest X-ray or left lateral decubitus abdominal X-rayQ
Radiology
null
d66c9834-4b3e-4b80-8841-4c7e1d962fc6
Benzodiazepine without anticonvulsant propey is?
Nitrazepam
Diazepam
Clonazepam
Temazepam
3d
single
Ans. is 'd' i.e., Temazepam BZDs with significant anticonvulsant propey are diazepam, clonazepam, nitrazepam, lorazepam and flurazepam.
Pharmacology
null
ff2354a9-2811-43a4-97d9-3c4091612557
A tumor has the following characteristics. Retrobulbar location within the muscle cone, well defined capsule, presents with slowly progressive proptosis, easily resectable, occurs most commonly in the 2nd to 4th decade. Most likely diagnosis is -
Capillary hemangioma
Cavernous hemangioma
Lymhangioma
Hemangiopericytoma
1b
single
Cavernous hemangioma is the most common benign, intraconal tumor in adults. Hemangiopericytoma is also retrobulbar intraconal lesion found in adults but is a rare tumor Moreover owing to its tendency to invade the adjacent tissues, its margins are less distinct than cavernous hemangioma. Rest 2 options i.e. Dermoid and...
Ophthalmology
null
06b2f598-c663-4932-90cc-742770fe5e9f
MgCl2 is added to polio vaccine because of the following -
Potentiates the vaccine
Vaccine can be kept at higher temperatures
Preservative
None of the above
1b
multi
molar MgCl2 is used to dtabilise the vaccine against heat inactivation REF:ANATHANARAYANAN MICROBIOLOGY NINTH EDITION PAGE.488
Microbiology
Virology