smiles
stringlengths
13
37
canonsmiles
stringlengths
12
39
isSmilesEqual
bool
2 classes
generic_scaffold
stringlengths
12
31
scaffold
stringlengths
0
37
rdkit_WT
float64
146
259
rdkit_MR
float64
29.7
65.2
rdkit_LogP
float64
-3.99
5.42
rdkit_HA
float64
0
7
rdkit_HD
float64
0
5
rdkit_NumAtoms
float64
10
35
rdkit_TPSA
float64
0
158
CCOC1=C(Cl)C=C(O)C(=N)N=N1
CCOc1nnc(=N)c(O)cc1Cl
false
CCCC1CCC(C)C(C)CC1C
N=c1ccccnn1
201.613
45.7305
0.71377
5
2
21
79.09
CC12COC=C1CN(O)C(=S)N2O
CC12COC=C1CN(O)C(=S)N2O
true
CC1CC2CCCC2(C)C(C)C1C
S=C1NCC2=COCC2N1
202.235
47.156
0.3401
4
2
23
56.17
NC(=S)N1OC2COCCC22CC12
NC(=S)N1OC2COCCC23CC13
false
CC(C)C1CC2CCCCC23CC13
C1CC23CC2NOC3CO1
200.263
49.7714
0.0248
3
1
25
47.72
O=S1(=O)OC(=CC#N)C2=C1NN=N2
N#CC=C1OS(=O)(=O)c2[nH]nnc21
false
CCCC1CC(C)(C)C2CCCC12
C=C1OS(=O)(=O)c2[nH]nnc21
198.163
38.2435
-0.61192
6
1
15
108.73
CC1(O)CC(=C)C2(CCO2)S1(=O)=O
C=C1CC(C)(O)S(=O)(=O)C12CCO2
false
CC1CC(C)(C)C(C)(C)C12CCC2
C=C1CCS(=O)(=O)C12CCO2
204.247
46.6006
0.1862
4
1
25
63.6
NC1C=CC2=CC(=NS2)C#CC#C1
NC1C#CC#Cc2cc(sn2)C=C1
false
CC1CCCCC2CCC(CC1)C2
C1#CCC=Cc2cc(ns2)C#C1
186.239
53.7774
0.8521
3
1
19
38.91
O=S1(=O)CCCC11CN1C1CCC1
O=S1(=O)CCCC12CN2C1CCC1
false
CC1(C)CCCC12CC2C1CCC1
O=S1(=O)CCCC12CN2C1CCC1
201.291
50.0968
0.7594
3
0
28
37.15
CN(C1CC=CCC(C)=C1)C(N)=S
CC1=CC(N(C)C(N)=S)CC=CC1
false
CC1CCCCC(C(C)C(C)C)C1
C1=CCCC=CC1
196.319
60.4674
1.8267
1
1
29
29.26
CC(=C)OC(=C)CC1=NSC(=O)O1
C=C(C)OC(=C)Cc1nsc(=O)o1
false
CC(C)CC(C)CC1CCC(C)C1
O=c1ocns1
199.231
49.393
1.7027
5
0
22
52.33
CC1(C)C2C(CNC(N)=S)CCN12
CC1(C)C2C(CNC(N)=S)CCN21
false
CC(C)CCC1CCC2C1C2(C)C
C1CC2CN2C1
199.323
57.4681
0.3023
2
2
30
41.06
CC1CC(N)C2(CC2)N1C(=S)NO
CC1CC(N)C2(CC2)N1C(=S)NO
true
CCC(C)C1C(C)CC(C)C12CC2
C1CNC2(C1)CC2
201.295
53.3786
0.2042
3
3
28
61.52
CC(N)C12NC(=S)NC1C2C=NO
CC(N)C12NC(=S)NC1C2C=NO
true
CCCC1C2CC(C)CC12C(C)C
S=C1NC2CC2N1
200.267
52.8063
-0.9915
4
4
25
82.67
CCC(CCC1=CSN=C1)CC#N
CCC(CC#N)CCc1cnsc1
false
CCCC(CC)CCC1CCCC1
c1cnsc1
194.303
54.446
3.01558
3
0
27
36.68
CCC=NN=CC1=C2CNC2=CS1
CCC=NN=Cc1scc2c1CN2
false
CCCCCCC1CCC2CCC12
c1scc2c1CN2
193.275
58.0227
2.4883
4
1
24
36.75
CC1CC1C1CCCS(=O)(=O)CO1
CC1CC1C1CCCS(=O)(=O)CO1
true
CC1CC1C1CCCC(C)(C)CC1
O=S1(=O)CCCC(C2CC2)OC1
204.291
50.0318
1.1937
3
0
29
43.37
N=C1NNC(=S)N2CCC(=O)CC12
N=C1NNC(=S)N2CCC(=O)CC12
true
CC1CCC2C(C)CCC(C)C2C1
N=C1NNC(=S)N2CCC(=O)CC12
198.251
51.3311
-0.61013
3
3
23
68.22
N=C1SN=C2CC3=C(COC3)CN12
N=c1snc2n1CC1=C(COC1)C2
false
CC1CCC2CC3CCCC3CC12
N=c1snc2n1CC1=C(COC1)C2
195.247
47.5077
0.30697
5
1
22
50.9
CC1(C)C2CC1NNC(=S)NCC2
CC1(C)C2CCNC(=S)NNC1C2
false
CC1CCCC2CC(CC1)C2(C)C
S=C1NCCC2CC(C2)NN1
199.323
57.1651
0.7735
2
3
30
36.09
CNC1(C)C2COC1(CO)S2(=O)=O
CNC1(C)C2COC1(CO)S2(=O)=O
true
CCC1(C)C2CCC1(CC)C2(C)C
O=S1(=O)C2COC1C2
207.251
45.9413
-1.5197
5
2
26
75.63
CCC(C)C12COCC1OS2(=O)=O
CCC(C)C12COCC1OS2(=O)=O
true
CCC(C)C12CCCC1CC2(C)C
O=S1(=O)OC2COCC21
206.263
46.7978
0.5301
4
0
27
52.6
NN=CCC(C#C)S(=O)(=O)NC=N
C#CC(CC=NN)S(=O)(=O)NC=N
false
CCCCC(CC)C(C)(C)CCC
202.239
50.7566
-1.15073
5
3
23
108.4
CC1C=COC2CC3=C(SC=C3)C12
CC1C=COC2Cc3ccsc3C12
false
CC1CCCC2CC3CCCC3C12
C1=COC2Cc3ccsc3C2C1
192.283
53.941
2.9364
2
0
25
9.23
NC1=C2C(CC3=C2SN=C3)=NOC1
NC1=C2C(=NOC1)Cc1cnsc12
false
CC1CCCC2CC3CCCC3C12
C1=C2C(=NOC1)Cc1cnsc12
193.231
50.3124
0.7552
5
1
20
60.5
NC1C2=C(SN=N2)C2C(O)CC12N
NC1c2nnsc2C2C(O)CC12N
false
CC1CC2(C)C(C)C3CCCC3C12
C1CC2c3snnc3CC12
198.251
47.1206
-0.9028
6
3
23
98.05
CC(C)N1CC(CO)S(=O)(=O)C1=N
CC(C)N1CC(CO)S(=O)(=O)C1=N
true
CCC1CC(C(C)C)C(C)C1(C)C
N=C1NCCS1(=O)=O
206.267
49.3623
-0.57913
4
2
27
81.46
CNCCOC1=CSC2=C1CC=C2
CNCCOc1csc2c1CC=C2
false
CCCCCC1CCC2CCCC12
C1=Cc2sccc2C1
195.287
56.4787
1.9156
3
1
26
21.26
CNC1CNNC(=S)NC(C1)C#N
CNC1CNNC(=S)NC(C#N)C1
false
CCC1CCCC(C)CC(CC)C1
S=C1NCCCCNN1
199.283
53.7378
-1.16102
4
4
26
71.91
C=CCN(CCC1=CSN=C1)C=N
C=CCN(C=N)CCc1cnsc1
false
CCCC(CC)CCC1CCCC1
c1cnsc1
195.291
56.3717
1.78067
3
1
26
39.98
NC1CNNC2=NSC(O)=C2C=C1
NC1C=Cc2c(nsc2O)NNC1
false
CC1CCCC2CCC(C)C2CC1
C1=Cc2csnc2NNCC1
198.251
52.4136
0.1193
6
4
23
83.2
CC=CC1COC(C1N)S(O)(=O)=O
CC=CC1COC(S(=O)(=O)O)C1N
false
CCCC1CCC(C(C)(C)C)C1C
C1CCOC1
207.251
47.568
-0.2499
4
2
26
89.62
CC12CC(C1CCS2(=O)=O)C(O)=O
CC12CC(C(=O)O)C1CCS2(=O)=O
false
CC(C)C1CC2(C)C1CCC2(C)C
O=S1(=O)CCC2CCC21
204.247
46.0416
0.2843
3
1
25
71.44
CC1=NC(CC(NC(N)=S)=N1)C#C
C#CC1CC(NC(N)=S)=NC(C)=N1
false
CCC1CC(C)CC(CC(C)C)C1
C1=NC=NCC1
194.263
57.7031
0.042
3
2
23
62.77
CC(O)C(C)(N)CC1=NC(=O)SN1
CC(O)C(C)(N)Cc1nc(=O)s[nH]1
false
CC1CCC(CC(C)(C)C(C)C)C1
O=c1nc[nH]s1
203.267
50.7119
-0.5279
5
3
26
92
CC(ON=C1C=NSN1N)C(C)=C
C=C(C)C(C)ON=c1cnsn1N
false
CC(C)C(C)CCC1CCCC1C
N=c1cns[nH]1
200.267
51.1784
0.4553
6
1
25
65.43
CC(C=C)=CC1=C(CC=O)SN=C1
C=CC(C)=Cc1cnsc1CC=O
false
CCCC1CCCC1CC(C)CC
c1cnsc1
193.271
55.73
2.4738
3
0
24
29.96
O=CC1=NSC(C2COC2)=C1C#N
N#Cc1c(C=O)nsc1C1COC1
false
CCC1CCC(C2CCC2)C1CC
c1cc(C2COC2)sn1
194.215
45.7765
0.94108
5
0
19
62.98
NCCN(C1=CNC=C1)S(N)(=O)=O
NCCN(c1cc[nH]c1)S(N)(=O)=O
false
CCCC(C1CCCC1)C(C)(C)C
c1cc[nH]c1
204.255
50.3003
-1.0167
3
3
25
105.21
OC1CC2CC2(C1)C1=CSC=C1Cl
OC1CC2CC2(c2cscc2Cl)C1
false
CC1CC2CC2(C2CCCC2C)C1
c1cc(C23CCCC2C3)cs1
214.717
54.3548
2.8139
2
1
24
20.23
CC(O)C1NC(=S)NC(=C)C1CN
C=C1NC(=S)NC(C(C)O)C1CN
false
CCC1C(C)CC(C)CC1C(C)C
C=C1CCNC(=S)N1
201.295
56.0226
-0.6979
3
4
28
70.31
OC1C=CCS(=O)(=O)CCC1C#N
N#CC1CCS(=O)(=O)CC=CC1O
false
CCC1CCC(C)(C)CCCC1C
O=S1(=O)CC=CCCCC1
201.247
47.5206
-0.13822
4
1
24
78.16
NS(=O)(=O)C1=NC(C2CC2)C2CN12
NS(=O)(=O)C1=NC(C2CC2)C2CN12
true
CC(C)(C)C1CC(C2CC2)C2CC21
C1=NC(C2CC2)C2CN12
201.251
47.5482
-0.8927
4
1
24
75.53
CC#CC1CNN=CC2=NSN=C12
CC#CC1CNN=Cc2nsnc21
false
CCCC1CCCCC2CCCC12
C1=NNCCc2nsnc21
192.247
51.6967
0.5821
5
1
21
50.17
CONC(=S)N(CCN)C=CCO
CONC(=S)N(C=CCO)CCN
false
CCCCC(CCC)C(C)CCC
205.283
54.7289
-0.811
4
3
28
70.75
NC(=N)C12CCC(N1C=O)S2(=O)=O
N=C(N)C12CCC(N1C=O)S2(=O)=O
false
CCC1C2CCC1(C(C)C)C2(C)C
O=S1(=O)C2CCC1N2
203.223
44.4899
-1.37463
4
2
22
104.32
O=COC1C2=CC=NC2=CS1(=O)=O
O=COC1C2=CC=NC2=CS1(=O)=O
true
CCCC1C2CCCC2CC1(C)C
O=S1(=O)C=C2N=CC=C2C1
199.187
44.5148
-0.2339
5
0
18
72.8
O=C1OC2=C(NCCOCCN2)S1
O=c1oc2c(s1)NCCOCCN2
false
CC1CC2CCCCCCCC2C1
O=c1oc2c(s1)NCCOCCN2
202.235
50.6534
0.5553
6
2
23
63.5
CC12CC(C1O)S(=O)(=O)N(N)C=C2
CC12C=CN(N)S(=O)(=O)C(C1)C2O
false
CC1C2CC1(C)CCC(C)C2(C)C
O=S1(=O)NC=CC2CC1C2
204.251
46.605
-0.8413
4
2
25
83.63
COC(=C)C1=C(C)C(C)S(=O)(=O)N1
C=C(OC)C1=C(C)C(C)S(=O)(=O)N1
false
CCC(C)C1CC(C)(C)C(C)C1C
O=S1(=O)CC=CN1
203.263
50.3665
0.742
3
1
26
55.4
CCC1(C)CN1NC(=S)N(O)C=C
C=CN(O)C(=S)NN1CC1(C)CC
false
CCC(C)C(C)CC1CC1(C)CC
C1CN1
201.295
54.9582
1.0949
3
2
28
38.51
CC12CC(CO1)C(O2)S(=O)(=O)C#N
CC12CC(CO1)C(S(=O)(=O)C#N)O2
false
CCC(C)(C)C1CC2(C)CCC1C2
C1OC2CC1CO2
203.219
41.8698
-0.00872
5
0
22
76.39
CC1(C)C2CN(N)C(=S)N(N)C12C
CC1(C)C2CN(N)C(=S)N(N)C21C
false
CC1CC2C(C)(C)C2(C)C(C)C1C
S=C1NCC2CC2N1
200.311
55.1938
0.051
3
2
29
58.52
CCC=C1COC2C1COS2(=O)=O
CCC=C1COC2C1COS2(=O)=O
true
CCCC1CCC2C1CCC2(C)C
C=C1COC2C1COS2(=O)=O
204.247
46.4758
0.6553
4
0
25
52.6
CC1(CN(C=N)C(=S)NN=C1)C#C
C#CC1(C)C=NNC(=S)N(C=N)C1
false
CCC1CC(C)(CC)CCCC1C
S=C1NCCC=NN1
194.263
56.6554
0.40887
3
2
23
51.48
OC1=C2N(CC(C#C)C2=NS1)C=O
C#CC1CN(C=O)c2c1nsc2O
false
CCC1CC(CC)C2C(C)CCC12
c1snc2c1NCC2
194.215
48.7628
0.5419
4
1
19
53.43
CC1COC(C)(C1)C1=NSNC1=O
CC1COC(C)(c2ns[nH]c2=O)C1
false
CC1CCC(C)(C2CCCC2C)C1
O=c1[nH]snc1C1CCCO1
200.263
49.8197
1.103
4
1
25
54.98
CCC(O)C1CC1NC(=S)NC=O
CCC(O)C1CC1NC(=S)NC=O
true
CCCC(C)CC1CC1C(C)CC
C1CC1
202.279
53.1262
-0.2337
3
3
27
61.36
CC(CO)(NCC=O)C1=NN=CS1
CC(CO)(NCC=O)c1nncs1
false
CCCCC(C)(CC)C1CCCC1
c1nncs1
201.251
48.4135
-0.4659
6
2
24
75.11
OC1CC2N(C1)C1=C(SN=C21)C#C
C#Cc1snc2c1N1CC(O)CC21
false
CCC1CCC2C3CC(C)CC3C12
c1snc2c1N1CCCC21
192.243
50.7598
0.7501
4
1
21
36.36
NC1CN(C2=CC(=C)OC2)S1(=O)=O
C=C1C=C(N2CC(N)S2(=O)=O)CO1
false
CC1CCC(C2CC(C)C2(C)C)C1
C=C1C=C(N2CCS2(=O)=O)CO1
202.235
46.7762
-0.6556
4
1
23
72.63
OC1=C2CC3COC=C3N2C(=N)S1
N=c1sc(O)c2n1C1=COCC1C2
false
CC1CC(C)C2C1CC1CCCC12
N=c1scc2n1C1=COCC1C2
196.231
47.2475
0.73557
5
2
21
58.24
CC1OC1C(C#N)C1=CSN=C1N
CC1OC1C(C#N)c1csnc1N
false
CCC(C1CCCC1C)C1CC1C
c1nscc1CC1CO1
195.247
49.2154
1.11978
5
1
22
75.23
CCN=C(N(C)N)C1=CNSC1=O
CCN=C(c1c[nH]sc1=O)N(C)N
false
CCCC(C(C)C)C1CCCC1C
O=c1cc[nH]s1
200.267
53.9681
0.0084
4
2
25
74.48
CN1CC2(COC2)C=CCNC1=S
CN1CC2(C=CCNC1=S)COC2
false
CC1CCCCC2(CCC2)CC1C
S=C1NCC=CC2(CN1)COC2
198.291
55.6227
0.3791
2
1
27
24.5
CC1=NSC(=C1N)C1=COCCC1
Cc1nsc(C2=COCCC2)c1N
false
CC1CCC(C2CCCCC2)C1C
C1=C(c2ccns2)CCCO1
196.275
54.4264
2.18502
4
1
25
48.14
CC1CC#CCC2=NC(=CS2)C1O
CC1CC#CCc2nc(cs2)C1O
false
CC1CCCCC2CCC(C2)C1C
C1#CCc2nc(cs2)CCC1
193.271
52.3348
1.7622
3
1
24
33.12
CC(=C)C(=O)C1CC=CS(=O)(=O)O1
C=C(C)C(=O)C1CC=CS(=O)(=O)O1
false
CC(C)C(C)C1CCCC(C)(C)C1
O=S1(=O)C=CCCO1
202.231
47.3708
0.764
4
0
23
60.44
CC(C#N)=C(N)C=CC1=NN=CS1
CC(C#N)=C(N)C=Cc1nncs1
false
CCC(C)C(C)CCC1CCCC1
c1nncs1
192.247
51.4434
1.30758
5
1
21
75.59
CC(=O)C1=NC(CNCC=O)=CS1
CC(=O)c1nc(CNCC=O)cs1
false
CCCCCC1CCC(C(C)C)C1
c1cscn1
198.247
49.8892
0.6342
5
1
23
59.06
O=C(NCC#N)S(=O)(=O)C1CCN1
N#CCNC(=O)S(=O)(=O)C1CCN1
false
CCCCC(C)C(C)(C)C1CCC1
C1CNC1
203.223
44.3392
-1.04622
5
2
22
99.06
CC1=C2C(CC3=NSC=C23)C(N)C1
CC1=C2c3csnc3CC2C(N)C1
false
CC1CC(C)C2C1CC1CCCC12
C1=C2c3csnc3CC2CC1
192.287
54.4944
1.8199
3
1
25
38.91
C=C1C=C(OCC2=C1SC=C2)C#N
C=C1C=C(C#N)OCc2ccsc21
false
CCC1CCC2CCCC2C(C)C1
C=C1C=COCc2ccsc21
189.239
51.838
2.69898
3
0
20
33.02
CCC1CNC(=S)N(C=O)C=C1C
CCC1CNC(=S)N(C=O)C=C1C
true
CCC1CCC(C)C(CC)CC1C
S=C1NC=CCCN1
198.291
56.0417
1.2629
2
1
27
32.34
NS(=O)(=O)C12CC(C1C#N)C(=N)N2
N#CC1C2CC1(S(N)(=O)=O)NC2=N
false
CCC1C2CC1(C(C)(C)C)CC2C
N=C1NC2CC1C2
200.223
43.9106
-1.28865
4
3
21
119.83
OCCC1CS(=O)(=O)CC2(O)CC12
O=S1(=O)CC(CCO)C2CC2(O)C1
false
CCCC1CC(C)(C)CC2(C)CC12
O=S1(=O)CCC2CC2C1
206.263
46.9034
-0.8356
4
2
27
74.6
OCCN1C(=C)C(=C)CCNC1=S
C=C1CCNC(=S)N(CCO)C1=C
false
CCCC1C(C)CCCC(C)C1C
C=C1CCNC(=S)NC1=C
198.291
57.2895
0.6288
2
2
27
35.5
CNC(=S)NC1=COCC(C)OC1
CNC(=S)NC1=COCC(C)OC1
true
CCC(C)CC1CCCC(C)CC1
C1=COCCOC1
202.279
54.2424
0.357
3
2
27
42.52
CNC1C(C)S(=O)(=O)N2C(C)C12C
CNC1C(C)S(=O)(=O)N2C(C)C12C
true
CCC1C(C)C(C)(C)C2C(C)C12C
O=S1(=O)CCC2CN21
204.295
50.9355
-0.2309
3
1
29
49.18
CCC1=NC(CN2CCN=C2)=CS1
CCc1nc(CN2C=NCC2)cs1
false
CCC1CCC(CC2CCCC2)C1
C1=NCCN1Cc1cscn1
195.291
55.261
1.5494
4
0
26
28.49
CC1C=C2C(C=NN2C(N)=S)C1C
CC1C=C2C(C=NN2C(N)=S)C1C
true
CC(C)C1CCC2C(C)C(C)CC12
C1=NNC2=CCCC12
195.291
57.0174
1.3173
2
1
26
41.62
CC1=CC(O)(CCCC1)S(O)(=O)=O
CC1=CC(O)(S(=O)(=O)O)CCCC1
false
CC1CCCCC(C)(C(C)(C)C)C1
C1=CCCCCC1
206.263
48.7234
1.0831
3
2
27
74.6
OC1=C2OCC(=C)CNN=C(O1)S2
C=C1CNN=C2OC(O)=C(OC1)S2
false
CC1CCCC2CC(C)C(CC1)C2
C=C1CNN=C2OC=C(OC1)S2
200.219
48.8605
0.8814
6
2
21
63.08
CC1=C(C=O)C(=NS1)C1CNN=C1
Cc1snc(C2C=NNC2)c1C=O
false
CCC1C(C)CCC1C1CCCC1
C1=NNCC1c1ccsn1
195.247
51.4742
0.93662
5
1
22
54.35
CC(=N)N1OCCOS(=O)(=O)C1=N
CC(=N)N1OCCOS(=O)(=O)C1=N
true
CC(C)C1CCCCC(C)(C)C1C
N=C1NOCCOS1(=O)=O
207.211
43.7902
-0.48806
6
2
22
103.54
CC1=C(C(=O)C#N)C2=C(CCC2)S1
Cc1sc2c(c1C(=O)C#N)CCC2
false
CCC(C)C1C(C)CC2CCCC21
c1cc2c(s1)CCC2
191.255
51.0245
2.2515
3
0
22
40.86
COC(C=O)S(=O)(=O)C(O)CC=C
C=CCC(O)S(=O)(=O)C(C=O)OC
false
CCCC(C)C(C)(C)C(CC)CC
208.235
46.6016
-0.5329
5
1
25
80.67
CC1(CNS(=O)(=O)NO)CC(O)C1
CC1(CNS(=O)(=O)NO)CC(O)C1
true
CCC(C)(C)CCC1(C)CC(C)C1
C1CCC1
210.255
45.1925
-1.0394
4
4
27
98.66
CC=CC1(C)NC(=S)NN=C1C=O
CC=CC1(C)NC(=S)NN=C1C=O
true
CCCC1(C)CC(C)CCC1CC
S=C1NCC=NN1
197.263
55.5874
0.3538
3
2
24
53.49
CC1=NC=C(C=C1N)S(=O)(=O)NO
Cc1ncc(S(=O)(=O)NO)cc1N
false
CCC(C)(C)C1CCC(C)C(C)C1
c1ccncc1
203.223
45.4944
-0.36028
5
3
22
105.31
COC1C(C(C)CS1(=O)=O)C(N)=N
COC1C(C(=N)N)C(C)CS1(=O)=O
false
CCC1C(C(C)C)C(C)CC1(C)C
O=S1(=O)CCCC1
206.267
49.1519
-0.42443
4
2
27
93.24
O=S1(=O)OC2CNN=C2NC11CC1
O=S1(=O)OC2CNN=C2NC12CC2
false
CC1(C)CC2CCCC2CC12CC2
O=S1(=O)OC2CNN=C2NC12CC2
203.223
44.3312
-1.2886
6
2
22
79.79
NC(=S)NC12CON=C1CCC=C2
NC(=S)NC12C=CCCC1=NOC2
false
CC(C)CC12CCCCC1CCC2
C1=CC2CON=C2CC1
197.263
54.4131
0.2946
3
2
24
59.64
NC(=O)C1=CC=CC(CCO)=C1Cl
NC(=O)c1cccc(CCO)c1Cl
false
CCCC1CCCC(C(C)C)C1C
c1ccccc1
199.637
50.7597
0.9737
2
2
23
63.32
CC(C1(CN1)C1CC1C)S(C)(=O)=O
CC1CC1C1(C(C)S(C)(=O)=O)CN1
false
CC1CC1C1(C(C)C(C)(C)C)CC1
C1CC1C1CN1
203.307
52.3105
0.4175
3
1
30
56.08
CS(=O)(=O)C1=NN2C(CC2=O)C1O
CS(=O)(=O)C1=NN2C(=O)CC2C1O
false
CC1CC2C(C)C(C(C)(C)C)CC12
O=C1CC2CC=NN12
204.207
43.5366
-1.6801
5
1
21
87.04
S=C1NC=NCC2C3OC3C=C2N1
S=C1NC=NCC2C(=CC3OC32)N1
false
CC1CCCCC2C(C1)CC1CC12
S=C1NC=NCC2C(=CC3OC32)N1
195.247
52.4624
-0.2265
3
2
22
48.95
ON=CN(C(=O)C=C)C1=NSC=C1
C=CC(=O)N(C=NO)c1ccsn1
false
CCCC(C(C)CC)C1CCCC1
c1cnsc1
197.219
50.0755
1.0796
5
1
20
65.79
OS(=O)(=O)C1=NC=C(CNN1)C=C
C=CC1=CN=C(S(=O)(=O)O)NNC1
false
CCC1CCCC(C(C)(C)C)CC1
C1=CN=CNNC1
203.223
48.402
-0.5921
5
3
22
90.79
C=NOCC12CS(=O)(=O)C(=C)C1O2
C=NOCC12CS(=O)(=O)C(=C)C1O2
true
CCCCC12CC1C(C)C(C)(C)C2
C=C1C2OC2CS1(=O)=O
203.219
46.0318
-0.3017
5
0
22
68.26
CC1CCC(=O)CC2=C(N)SC=C12
CC1CCC(=O)Cc2c1csc2N
false
CC1CCC(C)C2CCC(C)C2C1
O=C1CCCc2cscc2C1
195.287
55.0914
2.3392
3
1
26
43.09
CC(N=CNC(N)=S)C1(CN)CC1
CC(N=CNC(N)=S)C1(CN)CC1
true
CCC1(C(C)CCCC(C)C)CC1
C1CC1
200.311
58.5965
-0.0247
3
3
29
76.43