smiles
stringlengths
13
37
canonsmiles
stringlengths
12
39
isSmilesEqual
bool
2 classes
generic_scaffold
stringlengths
12
31
scaffold
stringlengths
0
37
rdkit_WT
float64
146
259
rdkit_MR
float64
29.7
65.2
rdkit_LogP
float64
-3.99
5.42
rdkit_HA
float64
0
7
rdkit_HD
float64
0
5
rdkit_NumAtoms
float64
10
35
rdkit_TPSA
float64
0
158
CCN1C(=S)N(CC1=C(C)C)N=C
C=NN1CC(=C(C)C)N(CC)C1=S
false
CCC1CC(C(C)C)C(CC)C1C
C=C1CNC(=S)N1
197.307
59.607
1.8183
2
0
28
18.84
CCC1=C(N)C(=NS1)C1OC1C=C
C=CC1OC1c1nsc(CC)c1N
false
CCC1CCC(C2CC2CC)C1C
c1cc(C2CO2)ns1
196.275
53.7154
1.9136
4
1
25
51.44
CC1C2CC1C(C)(C)NN2C(N)=S
CC1C2CC1C(C)(C)NN2C(N)=S
true
CC(C)C1CC(C)(C)C2CC1C2C
C1NNC2CC1C2
199.323
56.8981
0.8534
2
2
30
41.29
CC1=C(SC=C1Cl)C1COC1C=O
Cc1c(Cl)csc1C1COC1C=O
false
CCC1CCC1C1CCC(C)C1C
c1csc(C2COC2)c1
216.689
52.611
2.39122
3
0
22
26.3
C=CC12CC=NNC1S(=O)(=O)NN2
C=CC12CC=NNC1S(=O)(=O)NN2
true
CCC12CCCCC1C(C)(C)CC2
O=S1(=O)NNC2CC=NNC21
202.239
48.1519
-1.346
5
3
23
82.59
CC=CC(=C)C=C1NS(=O)(=O)CO1
C=C(C=CC)C=C1NS(=O)(=O)CO1
false
CCCC(C)CC1CCC(C)(C)C1
C=C1NS(=O)(=O)CO1
201.247
50.0445
0.8672
3
1
24
55.4
ClC1=C2C=C3C4=NC(C2N4)C1=C3Cl
Clc1c2cc3c(Cl)c1C1N=C2NC31
false
CC1C2CC3C(C)C1C1CC2CC31
c1c2cc3cc1C1N=C2NC31
211.051
51.6167
2.4526
2
1
17
24.39
ClC1=CC=CC2=C1OC=CCNN2
Clc1cccc2c1OC=CCNN2
false
CC1CCCC2CCCCCCC12
C1=COc2ccccc2NNC1
196.637
52.8454
2.1626
3
2
22
33.29
CCC1=C2CS(=O)(=O)ON2C(=N)O1
CCc1oc(=N)n2c1CS(=O)(=O)O2
false
CCC1CC(C)C2CC(C)(C)CC12
N=c1occ2n1OS(=O)(=O)C2
204.207
41.1345
-0.60503
6
1
21
85.29
CC1CC=CC(O1)(C#C)S(O)(=O)=O
C#CC1(S(=O)(=O)O)C=CCC(C)O1
false
CCC1(C(C)(C)C)CCCC(C)C1
C1=CCOCC1
202.231
47.4166
0.5687
3
1
23
63.6
CC1CC(CN1C(N)=S)C(=C)C#C
C#CC(=C)C1CC(C)N(C(N)=S)C1
false
CCC(C)C1CC(C)C(C(C)C)C1
C1CCNC1
194.303
59.0334
1.1298
1
1
27
29.26
CC1ON=C(C1N)C1=CSC(N)=C1
CC1ON=C(c2csc(N)c2)C1N
false
CC1CCC(C2CCC(C)C2C)C1
c1cc(C2=NOCC2)cs1
197.263
53.7908
0.7804
5
2
24
73.63
CCC1=C(O)SC(=N1)C1C(C)C1N
CCc1nc(C2C(C)C2N)sc1O
false
CCC1CC(C2C(C)C2C)CC1C
c1csc(C2CC2)n1
198.291
53.0372
1.4717
4
2
27
59.14
NC(=S)N1C2C3NCC1C=CC23N
NC(=S)N1C2C=CC3(N)C(NC2)C13
false
CC(C)C1C2CCC3C1C3(C)CC2
C1=CC2C3NCC1NC23
196.279
54.0495
-1.4781
3
3
25
67.31
COC1CCC23OS(=O)(=O)CC2C13
COC1CCC23OS(=O)(=O)CC2C13
true
CCC1CCC23CC(C)(C)CC2C13
O=S1(=O)CC2C3CCCC32O1
204.247
44.6138
0.14
4
0
25
52.6
CC1CCC(CN)ONC(=S)NN1
CC1CCC(CN)ONC(=S)NN1
true
CCC1CCC(C)CCC(C)CC1
S=C1NNCCCCON1
204.299
54.6285
-0.6037
4
4
29
71.34
NC1=CS(=O)(=O)CC2C(NC12)C#C
C#CC1NC2C(N)=CS(=O)(=O)CC12
false
CCC1CC2C(C)CC(C)(C)CC12
O=S1(=O)C=CC2NCC2C1
198.247
49.0919
-1.1953
4
2
23
72.19
CC(CS(N)(=O)=O)N(C=O)C(N)=O
CC(CS(N)(=O)=O)N(C=O)C(N)=O
true
CCC(C(C)C)C(C)CC(C)(C)C
209.227
44.9226
-1.7995
4
2
24
123.56
OCC1C2CCNC1S(=O)(=O)OC2
O=S1(=O)OCC2CCNC1C2CO
false
CCC1C2CCCC1C(C)(C)CC2
O=S1(=O)OCC2CCNC1C2
207.251
45.3453
-1.1095
5
2
26
75.63
C=CCC#CC1CN1S(=O)(=O)C#C
C#CS(=O)(=O)N1CC1C#CCC=C
false
CCCCCC1CC1C(C)(C)CC
C1CN1
195.243
50.8368
0.1706
2
0
22
37.15
OC1C2NNC(=S)N(C=C)C=CC12
C=CN1C=CC2C(O)C2NNC1=S
false
CCC1CCC2C(C)C2CCC1C
S=C1NC=CC2CC2NN1
197.263
53.3302
-0.3024
3
3
24
47.53
CC1=CC(=C)N(C(N)=S)C(=O)N1N
C=C1C=C(C)N(N)C(=O)N1C(N)=S
false
CC(C)C1C(C)CC(C)C(C)C1C
C=C1C=CNC(=O)N1
198.251
52.9438
0.2588
3
2
23
75.59
CC1=NN2C=CCCC=CC2=C1Cl
Cc1nn2c(c1Cl)C=CCCC=C2
false
CC1CC2CCCCCCC2C1C
C1=Cc2ccnn2C=CCC1
194.665
55.572
3.12262
2
0
24
17.82
C=C1C2CC(C=O)N2C2=NSN=C12
C=C1c2nsnc2N2C(C=O)CC12
false
CCC1CC2C(C)C3CCCC3C12
C=C1c2nsnc2N2CCC12
193.231
49.679
0.7111
5
0
20
46.09
NCC=CC1=C(Cl)C2=C(CNC2)N1
NCC=Cc1[nH]c2c(c1Cl)CNC2
false
CCCCC1CC2CCCC2C1C
c1cc2c([nH]1)CNC2
197.669
54.4348
1.2432
2
3
25
53.84
CN1CC=CC(NC1=S)=NC1CC1
CN1CC=CC(=NC2CC2)NC1=S
false
CC1CCCC(CC2CC2)CC1C
S=C1NCC=CC(=NC2CC2)N1
195.291
57.9607
0.9234
2
1
26
27.63
CN1CC(C1)C1=NSC(CC=O)=C1
CN1CC(c2cc(CC=O)sn2)C1
false
CCCC1CCC(C2CC(C)C2)C1
c1cc(C2CNC2)ns1
196.275
52.12
0.9135
4
0
25
33.2
NCC1=C(N=CS1)C(=C)COC=C
C=COCC(=C)c1ncsc1CN
false
CCCCC(C)C1CCCC1CC
c1cscn1
196.275
55.1884
1.7751
4
1
25
48.14
CC1(CN)NCC1(C)C1=NSC=N1
CC1(CN)NCC1(C)c1ncsn1
false
CCC1(C)CCC1(C)C1CCCC1
c1nc(C2CNC2)ns1
198.295
52.7231
0.1164
5
2
27
63.83
CC12C3CC1C(O)C1C3S(=O)(=O)C21
CC12C3CC1C1C(C3O)C2S1(=O)=O
false
CC1C2C3C4CC1C4(C)C2C3(C)C
O=S1(=O)C2C3CC4CC2C1C43
200.259
45.6966
-0.2013
3
1
25
54.37
N=C(NC(=S)N1CC1)C=CCC=O
N=C(C=CCC=O)NC(=S)N1CC1
false
CCCCCC(C)CC(C)C1CC1
C1CN1
197.263
54.8544
0.29897
3
2
24
55.96
NCC1=CN(N=CCC#C)C(=O)S1
C#CCC=Nn1cc(CN)sc1=O
false
CCCCCC1CC(CC)CC1C
O=c1[nH]ccs1
195.247
53.8104
0.2257
5
1
22
60.38
CC1=CC(=CS1)C(=O)OC1CNC1
Cc1cc(C(=O)OC2CNC2)cs1
false
CC1CCC(C(C)CC2CCC2)C1
O=C(OC1CNC1)c1ccsc1
197.259
51.1292
1.18512
4
1
24
38.33
CC#CC1=CN(N)S(=O)(=O)CC1O
CC#CC1=CN(N)S(=O)(=O)CC1O
true
CCCC1CC(C)C(C)(C)CC1C
O=S1(=O)CCC=CN1
202.235
47.353
-1.2264
4
2
23
83.63
CC1=NN2CC2CC1(C)S(O)(=O)=O
CC1=NN2CC2CC1(C)S(=O)(=O)O
false
CC1CC2CC2CC1(C)C(C)(C)C
C1=NN2CC2CC1
204.251
48.1736
0.0967
4
1
25
69.74
C=CC(C#N)C1NNC2=NSC=C12
C=CC(C#N)C1NNc2nscc21
false
CCC(CC)C1CCC2CCCC21
c1snc2c1CNN2
192.247
50.9134
1.44008
5
2
21
60.74
O=C1NCC23OCC2NS(=O)(=O)C13
O=C1NCC23OCC2NS(=O)(=O)C13
true
CC1CCC23CCC2CC(C)(C)C13
O=C1NCC23OCC2NS(=O)(=O)C13
204.207
41.3242
-2.4446
4
2
21
84.5
CC1C2CNCS(=O)(=O)C(N2)C1C
CC1C2CNCS(=O)(=O)C(N2)C1C
true
CC1C2CCCC(C)(C)C(C2)C1C
O=S1(=O)CNCC2CCC1N2
204.295
50.8292
-0.468
4
2
29
58.2
CN=C1CC(C)C(N1)C1=CC=CS1
CN=C1CC(C)C(c2cccs2)N1
false
CCC1CC(C)C(C2CCCC2)C1
N=C1CCC(c2cccs2)N1
194.303
57.3357
2.4469
2
1
27
24.39
CC12CC1N(C(N)=S)C1=NC=CN21
CC12CC1N(C(N)=S)c1nccn12
false
CC(C)C1C2CCCC2C2(C)CC12
c1cn2c(n1)NC1CC12
194.263
53.5444
0.4342
3
1
23
47.08
CN1OCCC(=C)CC(O)S1(=O)=O
C=C1CCON(C)S(=O)(=O)C(O)C1
false
CC1CCCC(C)C(C)(C)C(C)C1
C=C1CCONS(=O)(=O)CC1
207.251
47.0156
-0.152
4
1
26
66.84
CNC1C2C1(OC(C)S2(=O)=O)C#C
C#CC12OC(C)S(=O)(=O)C1C2NC
false
CCC1C2C(C)(C)C(C)CC12CC
O=S1(=O)COC2CC21
201.247
47.6665
-0.8804
4
1
24
55.4
OC12CNC1C(=C)CC1=CSC=C21
C=C1Cc2cscc2C2(O)CNC12
false
CC1CC2CCCC2C2(C)CCC12
C=C1Cc2cscc2C2CNC12
193.271
52.8505
1.0198
3
2
24
32.26
C#CC1CC2=C(O1)N1SC=CC1=N2
C#CC1Cc2nc3ccsn3c2O1
false
CCC1CC2CC3CCCC3C2C1
c1cc2nc3c(n2s1)OCC3
190.227
50.022
1.3325
4
0
19
26.53
NN=CC(=C)C1=CCC2=C1N=NS2
C=C(C=NN)C1=CCc2snnc21
false
CCCC(C)C1CCC2CCCC21
C1=Cc2nnsc2C1
192.247
53.4094
0.9783
5
1
21
64.16
CC(O)C(O)C1=NC2=C(S1)C=NS2
CC(O)C(O)c1nc2sncc2s1
false
CC(C)C(C)C1CC2CCCC2C1
c1nc2sncc2s1
216.287
51.9326
1.167
6
2
21
66.24
O=CC1=CS(=O)(=O)C2=CNN=CN12
O=CC1=CS(=O)(=O)C2=CNN=CN12
true
CCC1CC(C)(C)C2CCCCC12
O=S1(=O)C=CN2C=NNC=C21
199.191
44.6165
-0.8975
6
1
18
78.84
CNS(=O)(=O)N=C(OC)N(C)OC
CNS(=O)(=O)N=C(OC)N(C)OC
true
CCC(C)C(CC)CC(C)(C)CC
211.243
47.1955
-1.0538
4
1
26
80.23
ClC1=C2ON=C1C#CC1OC1CO2
Clc1c2noc1OCC1OC1C#C2
false
CC1C2CCC3CC3CCC1CC2
C1#CC2OC2COc2cc1no2
197.577
42.547
0.8393
4
0
17
47.79
CC=NN=C1SC=C2N1N=CC2=C
C=c1cnn2c(=NN=CC)scc12
false
CCCCC1CCC2C(C)CCC12
C=c1cnn2c(=N)scc12
192.247
53.538
0.4314
5
0
21
42.02
CCC1OC1C1(CC1)NC(=S)NO
CCC1OC1C1(NC(=S)NO)CC1
false
CCC(C)CC1(C2CC2CC)CC1
C1CC1C1CO1
202.279
51.5729
0.5497
3
3
27
56.82
COC(=O)OC1C=CC2=CSC=C12
COC(=O)OC1C=Cc2cscc21
false
CCC(C)CC1CCC2CCCC21
C1=Cc2cscc2C1
196.227
49.584
2.599
4
0
21
35.53
C=CC1C(C=C)=CC(=C)NS1(=O)=O
C=CC1=CC(=C)NS(=O)(=O)C1C=C
false
CCC1CC(C)CC(C)(C)C1CC
C=C1C=CCS(=O)(=O)N1
197.259
53.4605
1.1001
2
1
24
46.17
CC(=C)C1CCC2(N)C1OS2(=O)=O
C=C(C)C1CCC2(N)C1OS2(=O)=O
false
CC(C)C1CCC2(C)C1CC2(C)C
O=S1(=O)OC2CCCC21
203.263
48.2492
0.3561
4
1
26
69.39
CNC1=CSC(=C1)C(C#N)C(C)C
CNc1csc(C(C#N)C(C)C)c1
false
CCC1CCC(C(CC)C(C)C)C1
c1ccsc1
194.303
57.0577
3.05298
3
1
27
35.82
COC1=C2SC(C)=NN2C=C1C=C
C=Cc1cn2nc(C)sc2c1OC
false
CCC1CC2CC(C)CC2C1CC
c1cc2scnn2c1
194.259
54.449
2.35582
4
0
23
26.53
N=C1SN(C=NOCCC#C)C=N1
C#CCCON=Cn1cnc(=N)s1
false
CCCCCCCC1CCC(C)C1
N=c1nc[nH]s1
196.235
49.2507
0.25537
6
1
21
63.26
O=C1C2ONC(=S)NC1C(=C2)C#C
C#CC1=CC2ONC(=S)NC1C2=O
false
CCC1CC2CCC(C)CC1C2C
O=C1C2C=CC1ONC(=S)N2
194.215
49.4534
-0.7248
3
2
19
50.36
CN=CNOCS(=O)(=O)CCC#C
C#CCCS(=O)(=O)CONC=NC
false
CCCCCCC(C)(C)CCCC
204.251
50.7405
-0.4387
4
1
25
67.76
CC1CC(O)COC(C#C)S1(=O)=O
C#CC1OCC(O)CC(C)S1(=O)=O
false
CCC1CCC(C)CC(C)C1(C)C
O=S1(=O)CCCCOC1
204.247
47.5786
-0.4698
4
1
25
63.6
CC1CC=NOS(=O)(=O)C(N)C1C
CC1CC=NOS(=O)(=O)C(N)C1C
true
CC1CCCCC(C)(C)C(C)C1C
O=S1(=O)CCCCC=NO1
206.267
49.4172
0.2793
5
1
27
81.75
CN(O)S(=O)(=O)C#CC1NC1C=O
CN(O)S(=O)(=O)C#CC1NC1C=O
true
CCC1CC1CCC(C)(C)C(C)C
C1CN1
204.207
43.021
-1.8626
5
2
21
96.62
CC=CN1SC(C=C1)=NN1CCC1
CC=Cn1ccc(=NN2CCC2)s1
false
CCCC1CCC(CC2CCC2)C1
c1cc(=NN2CCC2)s[nH]1
195.291
55.066
1.5616
4
0
26
20.53
C=C1C=CC2CON3C12CS3(=O)=O
C=C1C=CC2CON3C12CS3(=O)=O
true
CC1CCC2CCC3C(C)(C)CC123
C=C1C=CC2CON3C12CS3(=O)=O
199.231
46.0788
0.058
3
0
22
46.61
N=CNOCC12CC(N1)S(=O)(=O)C2
N=CNOCC12CC(N1)S(=O)(=O)C2
true
CCCCCC12CC(C1)C(C)(C)C2
O=S1(=O)CC2CC1N2
205.239
45.9299
-1.39873
5
3
24
91.28
ONC1=C(SC=C1)C(=C)OC=NO
C=C(OC=NO)c1sccc1NO
false
CCCCC(C)C1CCCC1CC
c1ccsc1
200.219
50.1257
1.954
6
3
21
74.08
CC1=C(N)OC=C1OC1=CC=CS1
Cc1c(Oc2cccs2)coc1N
false
CC1CCC(CC2CCCC2)C1C
c1csc(Oc2ccoc2)c1
195.243
52.2504
3.02402
4
1
22
48.39
COC1CC(=C)C2(CO2)CS1(=O)=O
C=C1CC(OC)S(=O)(=O)CC12CO2
false
CCC1CC(C)C2(CC2)CC1(C)C
C=C1CCS(=O)(=O)CC12CO2
204.247
47.0238
0.1026
4
0
25
55.9
CC#CC(C)(N)C1=C2CCC2=CS1
CC#CC(C)(N)c1scc2c1CC2
false
CCCC(C)(C)C1CCC2CCC21
c1scc2c1CC2
191.299
56.7164
2.0439
2
1
26
26.02
CCC(C=C(C)N=CN)S(C)(=O)=O
CCC(C=C(C)N=CN)S(C)(=O)=O
true
CCCC(C)CC(CC)C(C)(C)C
204.295
55.3592
0.7004
3
1
29
72.52
CCCC1CNC2=C1C(Cl)=CN2N
CCCC1CNc2c1c(Cl)cn2N
false
CCCC1CCC2C(C)CC(C)C12
c1cc2c([nH]1)NCC2
199.685
55.7311
2.1645
3
2
27
42.98
CC(=N)N1NC(=S)NC2=CC=CC12
CC(=N)N1NC(=S)NC2=CC=CC21
false
CC1CC2CCCC2C(C(C)C)C1
S=C1NNC2C=CC=C2N1
194.263
55.1201
0.50057
2
3
23
51.15
CC(=C)ON1SC(O)=C2CNN=C12
C=C(C)ON1SC(O)=C2CNN=C21
false
CC(C)CC1CC(C)C2CCCC12
C1=C2CNN=C2NS1
199.235
50.4215
1.1017
6
2
22
57.09
CC1=NOS(=O)(=O)C2=NCCN2O1
CC1=NOS(=O)(=O)C2=NCCN2O1
true
CC1CCC(C)(C)C2CCCC2C1
O=S1(=O)ON=CON2CCN=C21
205.195
43.2068
-0.717
7
0
20
80.56
CC1CS(=O)(=O)C(C)C11NCC=C1
CC1CS(=O)(=O)C(C)C12C=CCN2
false
CC1CC(C)(C)C(C)C12CCCC2
O=S1(=O)CCC2(C=CCN2)C1
201.291
52.2865
0.3376
3
1
28
46.17
NN1C=CC23CC(NN2C1=S)C=C3
NN1C=CC23C=CC(C2)NN3C1=S
false
CC1CCC23CCC(CC2C1C)C3
S=C1NC=CC23C=CC(C2)NN13
194.263
53.0151
-0.1382
3
2
23
44.53
CC(N(C)C(=S)NN)C1=COCC1
CC(C1=COCC1)N(C)C(=S)NN
false
CCC(C)C(C)C(C)C1CCCC1
C1=COCC1
201.295
55.7981
0.3591
3
2
28
50.52
NS(=O)(=O)C1=CC(O)CC1=NN=C
C=NN=C1CC(O)C=C1S(N)(=O)=O
false
CCCC1CC(C)CC1C(C)(C)C
N=C1C=CCC1
203.223
48.798
-1.02
5
2
22
105.11
OC1C=C2CC3OC3CC2S1(=O)=O
O=S1(=O)C(O)C=C2CC3OC3CC21
false
CC1CC2CC3CC3CC2C1(C)C
O=S1(=O)CC=C2CC3OC3CC21
202.231
44.6926
-0.4106
4
1
23
66.9
N=C1N2C=CCN2C2=C1NSC2=O
N=c1c2[nH]sc(=O)c2n2n1C=CC2
false
CC1CCC2C(C)C3CCCC3C12
N=c1c2[nH]sc(=O)c2n2n1C=CC2
194.219
49.6104
0.15637
5
2
19
66.57
CC(=O)C(C(=O)NC=C)S(C)(=O)=O
C=CNC(=O)C(C(C)=O)S(C)(=O)=O
false
CCCC(C)C(C(C)C)C(C)(C)C
205.235
47.6525
-0.7517
4
1
24
80.31
C=C(CC1COC2=C1C=CS2)C=O
C=C(C=O)CC1COc2sccc21
false
CCC(C)CC1CCC2CCCC21
c1cc2c(s1)OCC2
194.255
52.376
2.3693
3
0
23
26.3
NCC1CC=CNC(=S)N1C(N)=O
NCC1CC=CNC(=S)N1C(N)=O
true
CCC1CCCCC(C)C1C(C)C
S=C1NC=CCCN1
200.267
53.7555
-0.5137
3
3
25
84.38
CC1=CCCC1NC1=C(C)SN=N1
CC1=CCCC1Nc1nnsc1C
false
CC1CCCC1CC1CCCC1C
C1=CC(Nc2csnn2)CC1
195.291
55.0477
2.36712
4
1
26
37.81
CS(=O)(=O)C12CCOC1C=CC2O
CS(=O)(=O)C12CCOC1C=CC2O
true
CC1CCC2CCCC12C(C)(C)C
C1=CC2OCCC2C1
204.247
47.0786
-0.5106
4
1
25
63.6
CCC1CC(C)CC2=C1C(O)=CS2
CCC1CC(C)Cc2scc(O)c21
false
CCC1CC(C)CC2CCC(C)C12
c1cc2c(s1)CCCC2
196.315
56.5008
3.5296
2
1
29
20.23
N1C=C2C=C1C=COC1=CSC2=C1
c1cc2cc(c[nH]2)c2cc(cs2)o1
false
C1CC2CCC(C2)C2CCC(C1)C2
c1cc2cc(c[nH]2)c2cc(cs2)o1
189.239
54.7617
3.5378
2
1
20
28.93
NN(CS(=O)(=O)OC1CNC1)C=O
NN(C=O)CS(=O)(=O)OC1CNC1
false
CCC(C)CC(C)(C)CC1CCC1
C1CNC1
209.227
43.6199
-2.4058
6
2
24
101.73
CCC1=C(N)C=C(Cl)C2=C1C(N)C2
CCc1c(N)cc(Cl)c2c1C(N)C2
false
CCC1C(C)CC(C)C2CC(C)C12
c1ccc2c(c1)CC2
196.681
55.8748
2.0405
2
2
26
52.04
ONC(=S)NCC(=C)C1=COCC1
C=C(CNC(=S)NO)C1=COCC1
false
CCC(C)CCC(C)C1CCCC1
C1=COCC1
200.263
53.3149
0.7001
3
3
25
53.52
CN1C(O)=C(N)N2C=C(Cl)C(N)=C12
Cn1c(O)c(N)n2cc(Cl)c(N)c12
false
CC1CC2C(C)C(C)C(C)C2C1C
c1cc2[nH]ccn2c1
200.629
51.8676
0.8012
5
3
22
81.61
NC1C2OC3CC2C1C1=C3SN=N1
NC1C2OC3CC2C1c1nnsc13
false
CC1C2CC3CC2C1C1CCCC31
C1C2OC3CC2C1c1nnsc13
195.247
46.3464
0.4224
5
1
22
61.03
C1CC2OC3=C(SN=C3)C(N1)C=C2
C1=CC2NCCC1Oc1cnsc12
false
C1CC2CCC(C1)C1CCCC1C2
C1=CC2NCCC1Oc1cnsc12
194.259
51.0307
1.4947
4
1
23
34.15
O=CCC1CN=C2N1C(=S)NC2=O
O=CCC1CN=C2C(=O)NC(=S)N21
false
CCCC1CCC2C(C)CC(C)C12
O=C1NC(=S)N2CCN=C12
197.219
49.3507
-0.9272
4
1
20
61.77
CC(N)C1=CC(C=C)=CC(C)=C1Cl
C=Cc1cc(C)c(Cl)c(C(C)N)c1
false
CCC1CC(C)C(C)C(C(C)C)C1
c1ccccc1
195.693
58.8824
3.31112
1
1
27
26.02
CC1(OCC2=C1SC=C2)C#CCO
CC1(C#CCO)OCc2ccsc21
false
CCCCC1(C)CCC2CCCC21
c1cc2c(s1)COC2
194.255
51.3218
1.4892
3
1
23
29.46
CC1CC1C(O)S(=O)(=O)CN(C)C
CC1CC1C(O)S(=O)(=O)CN(C)C
true
CC(C)CC(C)(C)C(C)C1CC1C
C1CC1
207.295
50.7516
-0.1053
4
1
30
57.61
CCC=NN1C=C(N)C(Cl)=C1CC
CCC=Nn1cc(N)c(Cl)c1CC
false
CCCCC1CC(C)C(C)C1CC
c1cc[nH]c1
199.685
57.4134
2.53
3
1
27
43.31
NN=CC(=C)C(=C)N1C=NSC1=O
C=C(C=NN)C(=C)n1cnsc1=O
false
CCCC(C)C(C)C1CCCC1C
O=c1[nH]cns1
196.235
53.5234
0.2762
6
1
21
73.27
CC=COC1=CC2=C(SC=C2C)S1
CC=COc1cc2c(C)csc2s1
false
CCCCC1CC2CCC(C)C2C1
c1cc2ccsc2s1
210.323
59.881
4.18362
3
0
23
9.23