index
int64
1
134k
A
float64
0
620k
B
float64
0.34
438
C
float64
0.33
283
mu
float64
0
29.6
alpha
float64
6.31
197
homo
float64
-0.43
-0.1
lumo
float64
-0.18
0.19
gap
float64
0.02
0.62
r2
float64
19
3.37k
zpve
float64
0.02
0.27
U0
float64
-714.57
-40.48
U
float64
-714.56
-40.48
H
float64
-714.56
-40.48
G
float64
-714.6
-40.5
Cv
float64
6
47
smiles
stringlengths
1
28
canonsmiles
stringlengths
1
34
isSmilesEqual
bool
2 classes
generic_scaffold
stringlengths
1
21
scaffold
stringlengths
0
31
rdkit_WT
float64
16
152
rdkit_MR
float64
3.61
43.7
rdkit_LogP
float64
-4.91
3.76
rdkit_HA
float64
0
7
rdkit_HD
float64
0
5
62,497
2.10545
1.42154
1.17763
3.2348
78.19
-0.232
0.0325
0.2645
1,155.399
0.156898
-419.2092
-419.199079
-419.198135
-419.243253
38.092
CC1(N)C(C#N)C1(C)O
CC1(N)C(C#N)C1(C)O
true
CCC1C(C)(C)C1(C)C
C1CC1
126.159
32.3192
-0.39182
3
2
118,354
2.38464
1.05191
0.79034
3.6546
84.23
-0.2365
0.0293
0.2658
1,519.4313
0.193341
-404.358887
-404.348739
-404.347794
-404.395112
36.459
CCCN(C=O)C1CC1
CCCN(C=O)C1CC1
true
CCCC(CC)C1CC1
C1CC1
127.187
36.083
1.0172
1
0
127,550
3.29238
1.46996
1.02274
2.4057
74.14
-0.2425
-0.0577
0.1848
1,098.4686
0.114634
-450.170538
-450.162543
-450.161598
-450.203829
28.937
CN1N=CC(=N)NC1=O
Cn1ncc(=N)[nH]c1=O
false
CC1CCC(C)C(C)C1
N=c1cn[nH]c(=O)[nH]1
126.119
29.6834
-1.41213
4
2
127,886
3.84486
1.20718
0.94595
4.4331
80.52
-0.2293
-0.0626
0.1667
1,229.8658
0.123846
-430.223134
-430.214523
-430.213579
-430.256744
30.842
CN=C1N=NNC(C)=N1
CN=c1nn[nH]c(C)n1
false
CCC1CCCC(C)C1
N=c1nc[nH]nn1
125.135
30.4017
-0.96138
4
1
15,585
2.81643
2.11535
1.45982
1.1988
66.11
-0.254
0.0327
0.2867
887.269
0.129328
-383.702954
-383.694943
-383.693999
-383.735774
28.883
CC1OCOC1C#C
C#CC1OCOC1C
false
CCC1CCCC1C
C1COCO1
112.128
29.12
0.381
2
0
109,223
4.68412
1.01814
0.91462
1.4928
77.68
-0.2086
0.0616
0.2701
1,321.7985
0.160178
-419.205723
-419.197131
-419.196187
-419.239148
32.254
COC1=NCC2(CC2)N1
COC1=NCC2(CC2)N1
true
CCC1CCC2(CC2)C1
C1=NCC2(CC2)N1
126.159
34.4117
0.1246
3
1
81,482
3.11992
1.47609
1.39696
1.6491
80.66
-0.2426
0.0837
0.3262
1,052.3172
0.184981
-387.055684
-387.04837
-387.047425
-387.086975
30.54
CC1C2OC1C1CCC21
CC1C2OC1C1CCC12
false
CC1C2CC1C1CCC21
C1C2OC1C1CCC21
124.183
34.039
1.4297
1
0
98,281
2.61554
1.01124
0.84584
2.5095
76.09
-0.2502
-0.0305
0.2197
1,420.876
0.169126
-440.270638
-440.260666
-440.259722
-440.306519
35.698
CC(C1CN1)C(=O)CO
CC(C(=O)CO)C1CN1
false
CCC(C)C(C)C1CC1
C1CN1
129.159
33.0475
-0.8443
3
2
15,098
5.5157
0.96261
0.88056
0.6043
82.12
-0.2418
-0.0231
0.2188
1,279.335
0.117303
-325.433615
-325.425452
-325.424508
-325.466631
29.566
C#CC#CCN1CC1
C#CC#CCN1CC1
true
CCCCCC1CC1
C1CN1
105.14
33.049
-0.0614
1
0
50,787
7.25967
0.61328
0.5655
5.4962
88.83
-0.2567
-0.074
0.1827
1,799.3804
0.087402
-415.572194
-415.563113
-415.562169
-415.607272
31.384
N=C(NC=O)C#CC#C
C#CC#CC(=N)NC=O
false
CCCCC(C)CCC
120.111
33.5354
-0.65373
2
2
78,039
2.51265
1.42778
1.26491
3.1575
77.23
-0.2407
0
0.2406
1,105.8263
0.157883
-419.165577
-419.156478
-419.155534
-419.198784
34.705
CC1(C)C2C(O)C(=N)N12
CC1(C)C2C(O)C(=N)N21
false
CC1C(C)C2C1C2(C)C
N=C1CC2CN12
126.159
33.4395
-0.19903
2
2
17,977
2.68718
2.43812
1.50568
0.7667
64.62
-0.2421
0.0962
0.3382
868.0675
0.155712
-422.057592
-422.050379
-422.049435
-422.088869
27.599
C1COCOCCO1
C1COCOCCO1
true
C1CCCCCCC1
C1COCOCCO1
118.132
27.59
0.0073
3
0
126,929
5.34755
0.91476
0.78885
7.402
76.63
-0.2406
-0.0696
0.171
1,405.0068
0.124029
-430.202559
-430.194064
-430.19312
-430.236942
29.916
CCNC1=CN=NN=N1
CCNc1cnnnn1
false
CCCC1CCCCC1
c1cnnnn1
125.135
31.7857
-0.3016
5
1
94,703
3.21446
1.23941
1.06172
0.5595
78
-0.2239
0.0713
0.2953
1,207.9056
0.182834
-424.216389
-424.207688
-424.206744
-424.249193
34.536
CC12CC1CC(O)CO2
CC12CC1CC(O)CO2
true
CC1CCC2(C)CC2C1
C1COC2CC2C1
128.171
33.0878
0.5462
2
1
104,576
2.28919
1.36331
1.07837
2.6994
75.32
-0.2434
-0.0158
0.2276
1,210.2492
0.169338
-440.277097
-440.267261
-440.266317
-440.312348
35.885
CC(=O)CC1(CO)CN1
CC(=O)CC1(CO)CN1
true
CCC1(CC(C)C)CC1
C1CN1
129.159
33.1175
-0.7002
3
2
24,165
5.2596
0.96677
0.85774
0.9341
74.3
-0.2083
0.0248
0.2331
1,327.0589
0.136319
-421.820105
-421.812375
-421.811431
-421.853136
29.42
C1CC1OC1=COC=C1
c1cc(OC2CC2)co1
false
C1CCC(CC2CC2)C1
c1cc(OC2CC2)co1
124.139
32.358
1.8208
2
0
86,859
3.01834
1.25268
1.03811
2.7072
66.81
-0.2878
-0.007
0.2809
1,129.652
0.113285
-453.968406
-453.960385
-453.95944
-454.001432
29.535
OC1CC(OC1=N)C#N
N#CC1CC(O)C(=N)O1
false
CCC1CC(C)C(C)C1
N=C1CCCO1
126.115
28.8365
-0.36295
4
2
12,808
3.45803
2.02315
1.53205
1.9938
72.6
-0.2402
0.0075
0.2477
884.6036
0.154574
-347.80652
-347.799174
-347.79823
-347.83784
28.613
CC12OC1CCC=C2
CC12C=CCCC1O2
false
CC12CCCCC1C2
C1=CC2OC2CC1
110.156
31.652
1.4939
1
0
51,413
3.88256
1.0054
0.98042
2.9422
80.71
-0.2363
-0.0202
0.216
1,266.3647
0.159725
-385.862487
-385.854656
-385.853712
-385.895807
30.19
O=CCC1C2C=CC1C2
O=CCC1C2C=CC1C2
true
CCCC1C2CCC1C2
C1=CC2CC1C2
122.167
34.908
1.3975
1
0
50,781
7.47747
0.48019
0.46747
2.8536
86.51
-0.2453
-0.0265
0.2188
2,297.9799
0.156749
-385.858587
-385.848551
-385.847607
-385.896614
34.53
O=CCC#CCC1CC1
O=CCC#CCC1CC1
true
CCCCCCC1CC1
C1CC1
122.167
35.798
1.3789
1
0
98,766
3.26633
1.2089
0.98641
4.9692
72.64
-0.2383
0.018
0.2563
1,222.804
0.147008
-439.061277
-439.052406
-439.051462
-439.095918
31.972
CNC(=O)C1OC2CC12
CNC(=O)C1OC2CC21
false
CCC(C)C1CC2CC21
C1OC2CC12
127.143
30.8347
-0.4803
2
1
18,616
2.91091
1.96384
1.61297
0.2217
80.27
-0.2154
0.0306
0.246
928.8955
0.177788
-311.879618
-311.871729
-311.870785
-311.911321
30.781
CC1C2CC=C(C)C12
CC1=CCC2C(C)C12
false
CC1CCC2C(C)C12
C1=CC2CC2C1
108.184
34.518
2.2185
0
0
98,831
2.93547
1.09129
0.96355
3.4147
71.8
-0.2511
-0.0369
0.2142
1,290.0496
0.157152
-460.1519
-460.14236
-460.141415
-460.187306
33.882
CC1COC1C(=O)CO
CC1COC1C(=O)CO
true
CCC(C)C1CCC1C
C1COC1
130.143
30.9968
-0.4173
3
1
36,651
4.42766
0.78238
0.75413
2.0551
81.34
-0.2378
0.0558
0.2936
1,542.1609
0.15809
-385.806848
-385.798032
-385.797088
-385.841365
32.851
C#CCCC1C2COC12
C#CCCC1C2COC12
true
CCCCC1C2CCC12
C1OC2CC12
122.167
34.787
1.0446
1
0
24,321
3.94645
1.67144
1.17415
3.3966
83.19
-0.1922
-0.0336
0.1586
974.295
0.117883
-379.748128
-379.742072
-379.741128
-379.778278
25.249
N1C=C2C=CC=NC2=C1
c1cnc2c[nH]cc2c1
false
C1CCC2CCCC2C1
c1cnc2c[nH]cc2c1
118.139
36.0937
1.5629
1
1
116,015
2.40691
1.25007
0.88466
0.7417
74.37
-0.2474
0.0122
0.2596
1,327.6791
0.158115
-460.153465
-460.144019
-460.143075
-460.188288
33.566
COC1OCC=C1CO
COC1OCC=C1CO
true
CCC1CCCC1CC
C1=CCOC1
130.143
31.9178
-0.0922
3
1
17,185
4.06191
1.86584
1.59094
1.4437
60.7
-0.2349
0.054
0.2889
815.8114
0.118424
-399.667496
-399.660655
-399.659711
-399.698666
25.879
OCC12NC3C1OC23
OCC12NC3C1OC32
false
CCC12CC3C1CC32
N1C2C3OC2C13
113.116
25.4015
-1.5297
3
2
28,224
5.03386
1.30013
1.0503
1.2982
65.33
-0.1904
0.0014
0.1918
1,079.2655
0.101304
-473.810839
-473.803409
-473.802465
-473.843029
26.774
CC1=NC2=C(OCO2)O1
Cc1nc2c(o1)OCO2
false
CC1CC2CCCC2C1
c1nc2c(o1)OCO2
127.099
27.363
0.71172
4
0
75,773
2.67303
1.24721
1.09727
3.1634
75.61
-0.2417
-0.0217
0.22
1,164.4807
0.131742
-421.798054
-421.788524
-421.787579
-421.832297
35.252
CC1C(=O)CC1(O)C#C
C#CC1(O)CC(=O)C1C
false
CCC1(C)CC(C)C1C
O=C1CCC1
124.139
32.5708
-0.0404
2
1
125,748
2.0843
1.6121
0.95424
1.9826
75.23
-0.2435
-0.0052
0.2383
1,226.9371
0.146345
-439.093566
-439.084097
-439.083153
-439.128234
33.654
CC1=C(CO)C(C)=NO1
Cc1noc(C)c1CO
false
CCC1C(C)CCC1C
c1cnoc1
127.143
31.8998
0.78374
3
1
92,088
2.55672
1.58741
1.24119
0.7889
78.12
-0.2255
0.083
0.3085
1,105.0381
0.182059
-424.206842
-424.198085
-424.197141
-424.239918
34.151
CC1OC2CC2OC1C
CC1OC2CC2OC1C
true
CC1CC2CC2CC1C
C1COC2CC2O1
128.171
33.287
0.9511
2
0
128,550
2.53989
1.50624
0.95121
3.0628
73.69
-0.2366
-0.0634
0.1732
1,149.5548
0.08733
-452.674579
-452.666473
-452.665529
-452.707813
28.733
COC1=C(ON=N1)C#C
C#Cc1onnc1OC
false
CCC1CCCC1CC
c1conn1
124.099
28.785
0.0595
4
0
55,507
3.39055
0.94323
0.76969
3.7344
68.09
-0.249
-0.0996
0.1495
1,427.1727
0.121102
-475.090781
-475.08095
-475.080006
-475.127327
33.97
CC(=O)C(=O)CC(N)=O
CC(=O)C(=O)CC(N)=O
true
CC(C)CC(C)C(C)C
129.115
29.4994
-0.9801
3
1
109,082
4.15247
1.02142
0.9303
1.6724
85.1
-0.2332
0.0231
0.2562
1,348.0145
0.183732
-387.093032
-387.084604
-387.08366
-387.126485
32.205
CCC1=CC2COC2C1
CCC1=CC2COC2C1
true
CCC1CC2CCC2C1
C1=CC2COC2C1
124.183
36.221
1.7415
1
0
57,986
4.03099
0.70856
0.6244
2.2635
78.5
-0.2614
-0.0315
0.2299
1,751.1769
0.155208
-423.016141
-423.005676
-423.004731
-423.052676
37.258
CC(O)C(=O)CCC#C
C#CCCC(=O)C(C)O
false
CCCCC(C)C(C)C
126.155
34.7548
0.3497
2
1
107,908
3.64515
1.24352
1.16938
3.3525
64.93
-0.2346
-0.009
0.2256
1,062.4511
0.111391
-457.698493
-457.690909
-457.689965
-457.731022
28.6
OCC12OC3C1C2C3=O
O=C1C2OC3(CO)C1C23
false
CCC12CC3C(C)C1C32
O=C1C2OC3C1C23
126.111
26.6768
-1.055
3
1
6,371
5.06976
0.98406
0.85959
3.408
72.26
-0.2509
-0.0221
0.2288
1,384.8064
0.174253
-386.174569
-386.164781
-386.163837
-386.209769
34.828
CCC(=O)CC(C)O
CCC(=O)CC(C)O
true
CCC(C)CC(C)C
116.16
31.5958
0.7364
2
1
3,746
6.76738
2.20545
1.68098
2.3359
56.45
-0.2132
0.028
0.2412
708.1475
0.103371
-340.657975
-340.651529
-340.650585
-340.688556
23.232
CN1C=CC(O)=N1
Cn1ccc(O)n1
false
CC1CCC(C)C1
c1cn[nH]c1
98.105
24.8728
0.1257
3
1
11,355
4.54025
1.19624
1.05613
2.1127
77.63
-0.2395
0.0173
0.2568
1,183.8131
0.177353
-349.024977
-349.016277
-349.015333
-349.058682
32.105
CCC1=CC(O)CC1
CCC1=CC(O)CC1
true
CCC1CCC(C)C1
C1=CCCC1
112.172
33.6148
1.4775
1
1
93,260
2.15766
1.63449
1.1893
3.2461
77.93
-0.2352
-0.0148
0.2205
1,129.9644
0.181008
-424.266885
-424.257196
-424.256252
-424.300895
36.738
CC1(C)C(O)CCC1=O
CC1(C)C(=O)CCC1O
false
CC1CCC(C)C1(C)C
O=C1CCCC1
128.171
34.0288
0.7364
2
1
70,655
2.4785
1.59459
1.18805
3.4346
72.18
-0.2486
0.0214
0.2699
1,055.8534
0.137311
-418.000611
-417.992653
-417.991709
-418.032929
30.875
OC12CC1CNC2C#N
N#CC1NCC2CC21O
false
CCC1CCC2CC12C
C1NCC2CC12
124.143
30.4605
-0.76722
3
2
65,111
3.17787
1.09766
0.99113
0.2067
92.1
-0.2217
0.0326
0.2543
1,344.8342
0.206613
-351.165996
-351.156896
-351.155951
-351.199989
35.3
CC1(CC1)C1=CCCC1
CC1(C2=CCCC2)CC1
false
CC1(C2CCCC2)CC1
C1=C(C2CC2)CCC1
122.211
39.275
2.8968
0
0
21,731
3.53787
1.91357
1.31326
5.1637
59.81
-0.2359
-0.0236
0.2123
885.8372
0.109339
-411.996617
-411.98946
-411.988516
-412.027953
26.778
NCC1=NON=C1N
NCc1nonc1N
false
CCC1CCCC1C
c1cnon1
114.108
26.6018
-0.8895
5
2
23,719
6.03645
1.56275
1.24138
1.9966
55.86
-0.247
-0.0592
0.1878
849.3959
0.073455
-438.740947
-438.73511
-438.734166
-438.770982
22.183
OC1=NC=C(F)N=C1
Oc1cnc(F)cn1
false
CC1CCC(C)CC1
c1cnccn1
114.079
23.6548
0.3213
3
1
43,461
2.85002
1.53221
1.08913
1.9189
66.9
-0.2609
-0.0475
0.2134
1,063.2515
0.111591
-457.813677
-457.806055
-457.80511
-457.846248
28.63
O=C1CC(=O)C2(CC2)O1
O=C1CC(=O)C2(CC2)O1
true
CC1CC(C)C2(CC2)C1
O=C1CC(=O)C2(CC2)O1
126.111
27.681
0.035
3
0
40,983
3.94054
1.57542
1.49931
0.3583
84.85
-0.2184
0.0047
0.2231
951.3037
0.16118
-348.633409
-348.627067
-348.626122
-348.663551
28.038
C1CC23C1C1C2C=CC31
C1=CC2C3C1C21CCC31
false
C1CC2C3C1C21CCC31
C1=CC2C3C1C21CCC31
118.179
34.767
1.8284
0
0
76,296
2.52567
1.63907
1.134
2.0818
64.16
-0.2689
-0.0239
0.245
1,034.6845
0.113744
-491.123916
-491.116025
-491.115081
-491.156328
30.047
OC1C(O)C(=O)NC1=N
N=C1NC(=O)C(O)C1O
false
CC1CC(C)C(C)C1C
N=C1CCC(=O)N1
130.103
27.883
-2.18473
4
4
120,660
2.95525
0.98706
0.85004
1.5354
80.06
-0.2348
0.0751
0.3099
1,450.3378
0.180953
-424.175292
-424.165819
-424.164875
-424.210395
34.368
CCOC1CC11COC1
CCOC1CC12COC2
false
CCCC1CC12CCC2
C1CC12COC2
128.171
33.283
0.8118
2
0
43,630
5.3974
0.84481
0.77011
2.0066
72.76
-0.2534
0.0305
0.2839
1,431.0695
0.148055
-439.080433
-439.071979
-439.071035
-439.115067
30.358
O=C1CC(N1)C1COC1
O=C1CC(C2COC2)N1
false
CC1CC(C2CCC2)C1
O=C1CC(C2COC2)N1
127.143
30.8567
-0.4787
2
1
8,829
3.17209
1.48899
1.17602
1.7226
63.72
-0.2483
-0.0013
0.247
1,040.0346
0.116734
-399.781914
-399.772772
-399.771827
-399.816152
31.438
COC(=O)C(N)C#C
C#CC(N)C(=O)OC
false
CCC(C)C(C)CC
113.116
28.8244
-0.8801
3
1
107,023
2.83199
1.25275
1.04276
0.8744
85.63
-0.2392
0.0793
0.3185
1,278.7228
0.203992
-388.256499
-388.246514
-388.24557
-388.290963
37.613
COC12CC1C(C)C2C
COC12CC1C(C)C2C
true
CCC12CC1C(C)C2C
C1CC2CC12
126.199
36.175
1.6773
1
0
56,039
3.71932
0.99939
0.92092
3.2646
68.18
-0.2485
0.0528
0.3013
1,300.8034
0.148432
-476.2713
-476.26243
-476.261486
-476.306415
31.84
NC(=O)OC1CCOC1
NC(=O)OC1CCOC1
true
CC(C)CC1CCCC1
C1CCOC1
131.131
29.8924
-0.1294
3
1
92,170
2.62224
1.93086
1.34362
2.2415
78.16
-0.1947
0.0844
0.2792
1,006.257
0.171397
-403.093004
-403.085213
-403.084269
-403.124742
31.562
CN1CC2OC3C2C13C
CN1CC2OC3C2C31C
false
CC1CC2CC3C2C13C
C1NC2C3OC1C23
125.171
33.186
0.0877
2
0
132,540
3.07992
1.35008
0.94412
2.0014
72.56
-0.2281
-0.0234
0.2047
1,168.5094
0.112799
-461.983114
-461.975326
-461.974382
-462.015611
29.244
CC1=CN=C(O)C(F)=C1
Cc1cnc(O)c(F)c1
false
CC1CCC(C)C(C)C1
c1ccncc1
127.118
30.5968
1.23472
2
1
42,378
8.56032
0.5908
0.55451
3.0199
83.38
-0.2635
-0.0976
0.1659
1,811.6792
0.074018
-398.307119
-398.297994
-398.29705
-398.342172
31.068
O=C(CC#CC#C)C#N
C#CC#CCC(=O)C#N
false
CCCCCC(C)CC
117.107
31.846
0.10578
2
0
22,246
3.38088
0.7546
0.71116
2.3482
76.35
-0.2441
0.0066
0.2508
1,663.7851
0.167246
-477.36815
-477.357189
-477.356245
-477.405015
38.297
COCC(O)C(C)=NO
COCC(O)C(C)=NO
true
CCCC(C)C(C)CC
133.147
32.7783
-0.1562
4
2
12,876
2.72546
2.33592
1.81028
2.7453
64.91
-0.2321
0.0023
0.2344
796.7003
0.130475
-383.723966
-383.716817
-383.715873
-383.754724
28.464
OC1C2CC=CC12O
OC1C2CC=CC12O
true
CC1C2CCCC12C
C1=CC2CC2C1
112.128
28.2036
-0.3319
2
2
83,350
2.13433
1.96154
1.56216
1.3624
81.27
-0.2364
0.0223
0.2587
994.529
0.184058
-387.102025
-387.093917
-387.092972
-387.133828
33.404
CC1C2CCC1(O)C=C2
CC1C2C=CC1(O)CC2
false
CC1C2CCC1(C)CC2
C1=CC2CCC1C2
124.183
35.9778
1.3334
1
1
58,657
1.88815
1.52541
1.18449
4.6129
80.48
-0.2481
0.0235
0.2716
1,186.0644
0.169612
-399.30458
-399.294431
-399.293487
-399.339247
37.127
CC(N)C1(CN1C)C#N
CC(N)C1(C#N)CN1C
false
CCC1(C(C)C)CC1C
C1CN1
125.175
34.6234
-0.45862
3
1
128,251
3.14477
1.37184
0.971
6.5294
74.44
-0.2349
-0.0578
0.1771
1,157.6928
0.113934
-446.282816
-446.27444
-446.273496
-446.316369
29.953
CNC1=NC(=N)N=NN1
CNc1nc(=N)nn[nH]1
false
CCC1CCCC(C)C1
N=c1nc[nH]nn1
126.123
29.5791
-1.27913
5
3
68,893
2.28023
1.75848
1.27629
1.2872
84.08
-0.2278
0.0235
0.2514
1,085.6687
0.182773
-387.094127
-387.085406
-387.084462
-387.126785
34.823
CC12CC1(O)CCC=C2
CC12C=CCCC1(O)C2
false
CC12CCCCC1(C)C2
C1=CC2CC2CC1
124.183
36.0478
1.4775
1
1
94,746
3.75405
1.14757
1.00776
3.5043
80.98
-0.2576
0.0182
0.2758
1,218.7239
0.161241
-382.084566
-382.076328
-382.075383
-382.117174
31.864
CC1CCC2(NC12)C#N
CC1CCC2(C#N)NC12
false
CCC12CCC(C)C1C2
C1CC2NC2C1
122.171
33.6657
0.65048
2
1
19,797
2.99224
2.73737
1.88796
3.261
62.56
-0.2238
0.0592
0.283
739.4956
0.133409
-379.860373
-379.854111
-379.853167
-379.890454
25.59
OC1C2NC2C2NC12
OC1C2NC2C2NC12
true
CC1C2CC2C2CC12
C1C2NC2C2NC12
112.132
27.4302
-1.9583
3
3
17,714
6.96667
1.52487
1.46264
2.7197
65.57
-0.2236
0.0011
0.2247
861.1667
0.118629
-362.574107
-362.567679
-362.566734
-362.604449
25.101
CN1C2C3C1C2C3=O
CN1C2C3C(=O)C2C31
false
CC1C2C3C(C)C2C13
O=C1C2C3NC2C13
109.128
27.326
-0.5023
2
0
121,665
4.1346
0.73607
0.67282
3.5638
75.2
-0.2485
0.0199
0.2685
1,677.0602
0.159924
-456.344371
-456.334803
-456.333858
-456.380222
34.005
OCCNC(=O)C1CN1
O=C(NCCO)C1CN1
false
CCCCC(C)C1CC1
C1CN1
130.147
31.8862
-1.9333
3
3
18,703
3.30818
2.28935
1.56833
1.9667
68.07
-0.244
0.0264
0.2704
835.2929
0.143934
-363.861954
-363.855039
-363.854094
-363.89296
26.939
CC1N=COC2CC12
CC1N=COC2CC12
true
CC1CCCC2CC12
C1=NCC2CC2O1
111.144
30.934
0.8219
2
0
106,755
2.12807
1.69139
1.13429
3.4355
73.7
-0.233
0.0071
0.2401
1,128.5189
0.145841
-439.069003
-439.059883
-439.058939
-439.102902
33.394
COC12CC1(C)NC2=O
COC12CC1(C)NC2=O
true
CCC12CC1(C)CC2C
O=C1NC2CC12
127.143
30.9047
-0.3362
2
1
48,710
3.52141
1.32663
1.13627
3.0515
79.88
-0.242
-0.0134
0.2285
1,106.9318
0.160651
-385.887992
-385.880517
-385.879573
-385.919786
30.132
O=CC12CC1C1CC1C2
O=CC12CC3CC3C1C2
false
CCC12CC3CC3C1C2
C1C2CC2C2CC12
122.167
32.818
1.2314
1
0
20,269
4.4492
2.63176
2.39012
1.65
70.09
-0.2224
0.0923
0.3147
664.7833
0.146446
-326.660327
-326.655309
-326.654365
-326.689007
22.267
C1C2C3C1N1C2CC31
C1C2C3C1N1C2CC31
true
C1C2C3CC4C2C1C34
C1C2C3C1N1C2CC31
107.156
29.417
0.4612
1
0
73,410
2.58625
2.28191
1.59512
1.617
80.29
-0.228
0.0852
0.3131
913.5491
0.1735
-365.969016
-365.962123
-365.961179
-365.99974
29.26
CC12CCC3C4C(C13)N24
CC12CCC3C4C(C31)N42
false
CC12CCC3C4C(C31)C42
C1CC2C3C1C1C3N21
121.183
34.034
0.8513
1
0
81,676
3.57645
1.31004
1.21566
2.7584
72.73
-0.2468
0.022
0.2688
1,065.2745
0.1494
-439.082999
-439.075468
-439.074524
-439.11496
30.072
OC1C2CC1OC(=N)C2
N=C1CC2CC(O1)C2O
false
CC1CC2CC(C1)C2C
N=C1CC2CC(C2)O1
127.143
31.3305
0.13337
3
2
132,595
3.15773
1.29686
0.92008
2.4614
72.98
-0.1933
0.006
0.1993
1,159.8006
0.113089
-461.977432
-461.969651
-461.968707
-462.009276
30.81
NC1=CC(F)=CC=C1O
Nc1cc(F)ccc1O
false
CC1CCC(C)C(C)C1
c1ccccc1
127.118
32.4772
1.1135
2
2
2,914
5.20152
2.27975
1.97268
2.3665
49.95
-0.254
-0.0337
0.2202
658.9679
0.101662
-381.585231
-381.578743
-381.577799
-381.616587
21.841
O=CC1COCO1
O=CC1COCO1
true
CCC1CCCC1
C1COCO1
102.089
21.756
-0.4418
3
0
35,635
3.27435
1.37813
1.07815
4.4654
77.42
-0.2473
-0.0042
0.2431
1,098.5338
0.138865
-380.872652
-380.86523
-380.864286
-380.904585
28.956
N#CC1CC=CC2NC12
N#CC1CC=CC2NC12
true
CCC1CCCC2CC12
C1=CC2NC2CC1
120.155
33.5717
0.42648
2
1
55,529
4.33162
0.89828
0.85421
3.3526
72.06
-0.2638
-0.0197
0.2441
1,390.3328
0.13488
-455.154902
-455.145718
-455.144774
-455.190193
32.12
CC(=N)OC(=O)C1CN1
CC(=N)OC(=O)C1CN1
true
CC(C)CC(C)C1CC1
C1CN1
128.131
31.2834
-0.50143
4
2
88,821
2.89204
1.10703
0.88415
1.5793
86.51
-0.2379
0.0849
0.3228
1,412.3136
0.205201
-388.264194
-388.254412
-388.253468
-388.299615
36.203
CC1CC1C1OCC1C
CC1CC1C1OCC1C
true
CC1CCC1C1CC1C
C1CC(C2CC2)O1
126.199
36.175
1.6773
1
0
2,484
4.74486
2.60119
2.39945
1.2978
63.27
-0.2571
0.083
0.3401
645.9474
0.151089
-309.706371
-309.700467
-309.699523
-309.735674
24.118
OC1CC2CC1C2
OC1CC2CC1C2
true
CC1CC2CC1C2
C1CC2CC1C2
98.145
26.8378
0.7772
1
1
112,679
2.65023
1.33488
1.10536
2.3608
71.7
-0.244
-0.0237
0.2204
1,171.9661
0.157651
-460.189622
-460.18042
-460.179476
-460.224006
33.426
COC1CC(=O)C(C)O1
COC1CC(=O)C(C)O1
true
CCC1CC(C)C(C)C1
O=C1CCOC1
130.143
30.968
0.3368
3
0
51,106
5.00935
0.963
0.91257
2.8679
72.17
-0.2459
-0.0185
0.2274
1,250.5302
0.12371
-437.896253
-437.888122
-437.887178
-437.929855
30.046
O=CNC12CC1C(=O)C2
O=CNC12CC(=O)C1C2
false
CCCC12CC(C)C1C2
O=C1CC2CC12
125.127
29.6617
-0.5361
2
1
126,344
2.84086
1.39479
1.00535
0.6941
79.74
-0.2358
-0.0549
0.1809
1,173.8946
0.136706
-417.990763
-417.98262
-417.981675
-418.023744
30.463
CCC1=CON=CC1=N
CCc1concc1=N
false
CCC1CCCCC1C
N=c1cconc1
124.143
31.7357
0.71647
3
1
63,610
2.91161
1.0595
0.94423
4.1157
82.31
-0.2514
-0.0605
0.1908
1,318.7913
0.144374
-401.906923
-401.8972
-401.896256
-401.941608
35.622
CC1(C)NC1C(=O)C#C
C#CC(=O)C1NC1(C)C
false
CCC(C)C1CC1(C)C
C1CN1
123.155
34.8427
-0.0609
2
1
75,518
2.5887
1.45257
1.11772
1.9142
82.85
-0.2344
0.0129
0.2473
1,166.704
0.1718
-403.14984
-403.141286
-403.140342
-403.182825
32.793
CC1=CCCN=COC1
CC1=CCCN=COC1
true
CC1CCCCCCC1
C1=CCOC=NCC1
125.171
37.685
1.3813
2
0
18,696
3.36556
2.41675
1.56565
3.5854
57.21
-0.2671
-0.0037
0.2634
775.9912
0.108772
-419.691648
-419.685369
-419.684425
-419.722246
23.845
O=C1OCOC2CC12
O=C1OCOC2CC12
true
CC1CCCC2CC12
O=C1OCOC2CC12
114.1
23.939
-0.0942
3
0
85,087
2.59069
1.34595
0.93357
4.1537
70.17
-0.2649
-0.0914
0.1735
1,203.951
0.111652
-457.826668
-457.818493
-457.817549
-457.859826
29.269
CC1OC(=O)C(C=O)=C1
CC1C=C(C=O)C(=O)O1
false
CCC1CC(C)CC1C
O=C1C=CCO1
126.111
29.701
0.057
3
0
75,091
3.30811
1.46005
1.08049
4.2497
76.49
-0.2118
-0.0042
0.2076
1,099.7123
0.137504
-418.033862
-418.025955
-418.025011
-418.066387
30.17
CC1=CNC(=O)N2CC12
CC1=CNC(=O)N2CC12
true
CC1CCC(C)C2CC12
O=C1NC=CC2CN12
124.143
32.7827
0.2976
1
1
106,823
2.44723
1.47677
1.10513
2.1087
71.43
-0.2512
0.0663
0.3174
1,133.1023
0.158738
-460.139416
-460.130534
-460.12959
-460.17287
33.629
OCC12CC1(O)COC2
OCC12COCC1(O)C2
false
CCC12CCCC1(C)C2
C1OCC2CC12
130.143
29.9046
-0.8699
3
2
46,277
3.19128
1.48411
1.2436
5.2148
64.64
-0.2635
-0.0009
0.2625
994.2599
0.112554
-457.736022
-457.728872
-457.727928
-457.767981
26.879
O=C1OCC11CC2OC12
O=C1OCC12CC1OC12
false
CC1CCC12CC1CC12
O=C1OCC12CC1OC12
126.111
26.67
-0.2993
3
0
90,896
2.33822
1.97779
1.43309
1.519
80.72
-0.2236
0.0831
0.3067
1,011.0568
0.18317
-387.071622
-387.063652
-387.062707
-387.103403
32.609
CC1OC2C3CC1(C)C23
CC1OC2C3CC1(C)C32
false
CC1CC2C3CC1(C)C23
C1OC2C3CC1C32
124.183
34.039
1.4297
1
0
27,437
2.50576
1.65396
1.05607
6.3125
80.18
-0.2263
-0.0761
0.1502
1,084.9759
0.114305
-416.845113
-416.837499
-416.836555
-416.877162
29.291
NC1=CC(=O)N=CC=C1
Nc1cccnc(=O)c1
false
CC1CCCCC(C)C1
O=c1cccccn1
122.127
34.9194
0.024
3
1
20,609
3.58008
1.95665
1.27522
3.9577
65.82
-0.2497
-0.0451
0.2046
878.0609
0.081884
-377.477636
-377.470366
-377.469422
-377.509258
26.051
CC1=C(N=NO1)C#C
C#Cc1nnoc1C
false
CCC1CCCC1C
c1conn1
108.1
26.97
0.35932
3
0
67,513
2.49062
1.51067
1.13897
2.5751
70.73
-0.2351
-0.0379
0.1972
1,070.6098
0.122436
-437.781406
-437.773485
-437.77254
-437.814122
30.22
OC12C(C=O)C1N1CC21
O=CC1C2N3CC3C12O
false
CCC1C2C3CC3C12C
C1C2C1N1CC21
125.127
28.7858
-1.3874
3
1
14,703
13.81155
0.51072
0.49862
0.0006
73.93
-0.2447
0.0561
0.3008
2,127.1143
0.151482
-384.902995
-384.892738
-384.891794
-384.940988
34.019
OCCC#CCCO
OCCC#CCCO
true
CCCCCCCC
114.144
31.1816
-0.2454
2
2
85,697
2.19107
1.53024
1.14971
3.4169
69.16
-0.2849
-0.0082
0.2768
1,102.4964
0.122519
-437.8523
-437.843808
-437.842864
-437.885911
30.714
CC1OC(C#N)C11CO1
CC1OC(C#N)C12CO2
false
CCC1CC(C)C12CC2
C1OCC12CO2
125.127
28.631
0.06628
3
0
28,354
3.21506
1.40501
0.98403
2.0823
79.57
-0.194
-0.0273
0.1667
1,156.1049
0.126257
-434.150281
-434.142091
-434.141147
-434.182699
31.268
CC1=CN=C(N)C(=O)N1
Cc1cnc(N)c(=O)[nH]1
false
CC1CCC(C)C(C)C1
O=c1cncc[nH]1
125.131
34.0071
-0.33948
3
2
118,229
2.03972
1.02138
0.74898
0.9567
87.42
-0.2394
0.0879
0.3272
1,661.5095
0.224692
-426.620501
-426.608512
-426.607568
-426.658685
42.226
COCC(C)OC(C)C
COCC(C)OC(C)C
true
CCCC(C)CC(C)C
132.203
37.559
1.4463
2
0
57,095
2.53708
1.30273
1.11596
1.2334
76.03
-0.2497
0.0476
0.2973
1,180.6484
0.15832
-422.991023
-422.981854
-422.98091
-423.025362
33.498
CC(C#C)C1COCO1
C#CC(C)C1COCO1
false
CCC(C)C1CCCC1
C1COCO1
126.155
33.689
0.6286
2
0
103,254
4.09292
1.03364
1.00257
3.7553
68.66
-0.2758
-0.0033
0.2726
1,208.8062
0.134256
-458.95193
-458.94322
-458.942276
-458.985397
32.14
CC1(CO)C2OC(=O)C12
CC1(CO)C2OC(=O)C21
false
CCC1(C)C2CC(C)C21
O=C1OC2CC12
128.127
28.5628
-0.4598
3
1
77,609
2.10546
1.61964
1.28483
3.8573
78.29
-0.2567
0.0164
0.273
1,079.3927
0.146852
-401.940649
-401.931726
-401.930781
-401.9739
33.409
CC12CCC1(C#N)C2O
CC12CCC1(C#N)C2O
true
CCC12CCC1(C)C2C
C1CC2CC12
123.155
31.3938
0.67098
2
1
3,249
6.02706
2.29139
2.1072
1.5928
64.43
-0.2255
0.08
0.3055
677.7337
0.137931
-288.573089
-288.567103
-288.566159
-288.602558
23.807
C1C2N1CC21CC1
C1C2N1CC21CC1
true
C1C2CC3(CC3)C12
C1C2N1CC21CC1
95.145
27.028
0.4644
1
0
106,302
3.20909
1.21565
1.12128
1.3992
85.41
-0.2373
0.0862
0.3235
1,247.1381
0.205647
-388.296652
-388.287564
-388.28662
-388.329984
35.927
CCC12CC(C)(CC1)O2
CCC12CCC(C)(C1)O2
false
CCC12CCC(C)(C1)C2
C1CC2CC1O2
126.199
36.363
2.108
1
0