index
int64
1
134k
A
float64
0
620k
B
float64
0.34
438
C
float64
0.33
283
mu
float64
0
29.6
alpha
float64
6.31
197
homo
float64
-0.43
-0.1
lumo
float64
-0.18
0.19
gap
float64
0.02
0.62
r2
float64
19
3.37k
zpve
float64
0.02
0.27
U0
float64
-714.57
-40.48
U
float64
-714.56
-40.48
H
float64
-714.56
-40.48
G
float64
-714.6
-40.5
Cv
float64
6
47
smiles
stringlengths
1
28
canonsmiles
stringlengths
1
34
isSmilesEqual
bool
2 classes
generic_scaffold
stringlengths
1
21
scaffold
stringlengths
0
31
rdkit_WT
float64
16
152
rdkit_MR
float64
3.61
43.7
rdkit_LogP
float64
-4.91
3.76
rdkit_HA
float64
0
7
rdkit_HD
float64
0
5
41,711
3.84999
1.43473
1.23448
1.4917
80.13
-0.2235
0.0153
0.2388
1,045.5554
0.162328
-385.891696
-385.884801
-385.883857
-385.922664
28.408
C1OCC23C=CCC2C13
C1=CC23COCC2C3C1
false
C1CC2C3CCCC23C1
C1=CC23COCC2C3C1
122.167
33.989
1.2089
1
0
18,691
3.14409
2.36135
1.51101
4.5516
64.27
-0.2561
0.0073
0.2634
828.9647
0.132801
-383.769708
-383.763078
-383.762133
-383.800711
25.504
O=C1OCCC2CC12
O=C1OCCC2CC12
true
CC1CCCC2CC12
O=C1OCCC2CC12
112.128
27.173
0.5694
2
0
62,004
3.99306
0.74577
0.64479
4.9569
67.55
-0.2608
0.0007
0.2615
1,625.4156
0.12359
-471.246956
-471.237065
-471.236121
-471.283332
34.575
NC(=O)NCC(O)C#N
N#CC(O)CNC(N)=O
false
CCC(C)CCC(C)C
129.119
29.2059
-1.46082
3
3
85,003
2.1741
1.60782
0.99313
4.2304
83.59
-0.2356
-0.0124
0.2232
1,233.1848
0.169681
-403.223438
-403.213371
-403.212426
-403.258943
36.029
CC1NC(=O)C(C)=C1C
CC1=C(C)C(C)NC1=O
false
CC1CC(C)C(C)C1C
O=C1C=CCN1
125.171
35.9787
0.8411
1
1
127,705
3.2922
1.50845
1.04127
5.568
71.86
-0.232
-0.0566
0.1754
1,072.0627
0.10136
-466.164753
-466.156658
-466.155714
-466.197504
29.362
CN1N=NC(=O)C(N)=N1
Cn1nnc(=O)c(N)n1
false
CC1CCC(C)C(C)C1
O=c1cn[nH]nn1
127.107
29.4804
-1.8475
6
1
35,879
2.21868
1.57366
1.1056
4.7843
77.43
-0.2475
0.019
0.2665
1,120.5464
0.136754
-380.845768
-380.836984
-380.83604
-380.880777
31.823
C#CC1CCNC1C#N
C#CC1CCNC1C#N
true
CCC1CCCC1CC
C1CCNC1
120.155
34.3437
0.12128
2
1
129,333
5.72602
0.98077
0.83735
4.1153
74.57
-0.2584
-0.0896
0.1687
1,260.8995
0.090053
-445.059178
-445.051763
-445.050819
-445.091677
26.46
N=CNC1=CN=NN=N1
N=CNc1cnnnn1
false
CCCC1CCCCC1
c1cnnnn1
124.107
30.0284
-0.71443
5
2
112,513
3.60645
0.94277
0.8501
3.6422
80.3
-0.277
0.0211
0.2981
1,415.5236
0.170398
-403.158602
-403.149027
-403.148083
-403.193308
35.103
CCC1CC(C#N)C1O
CCC1CC(C#N)C1O
true
CCC1CC(CC)C1C
C1CCC1
125.171
33.5078
0.91698
2
1
23,718
5.87275
1.4784
1.18108
2.216
55.08
-0.2567
-0.0437
0.213
868.277
0.072602
-446.709135
-446.703401
-446.702457
-446.739158
21.795
FC1=CN=C(F)C=C1
Fc1ccc(F)nc1
false
CC1CCC(C)CC1
c1ccncc1
115.082
24.153
1.3598
1
0
132,106
3.06752
1.4284
0.97537
3.4589
74
-0.19
-0.0374
0.1526
1,102.124
0.10079
-477.998851
-477.99116
-477.990216
-478.030922
29.637
NC1=C(F)C=CC(=N)O1
N=c1ccc(F)c(N)o1
false
CC1CCC(C)C(C)C1
N=c1cccco1
128.106
28.9331
0.48037
3
2
22,598
2.91239
1.22503
1.03239
1.7013
77.49
-0.2415
0.0147
0.2562
1,217.1711
0.144656
-438.970288
-438.961178
-438.960234
-439.003737
34.207
CC1C2OC1(C)C2=NO
CC1C2OC1(C)C2=NO
true
CCC1C2CC1(C)C2C
N=C1C2CC1O2
127.143
31.6635
0.6238
3
1
52,478
5.46168
0.52068
0.49391
3.0856
91.58
-0.2402
-0.0509
0.1893
2,163.6867
0.108772
-420.585022
-420.574862
-420.573918
-420.62381
33.762
CC#CC#CC(O)C=O
CC#CC#CC(O)C=O
true
CCCCCC(C)CC
122.123
33.2968
-0.4271
2
1
107,436
3.05756
1.43663
1.21548
1.9702
77.91
-0.2219
0.0792
0.301
1,101.5411
0.171701
-403.093541
-403.085522
-403.084578
-403.125852
31.723
COC12CC1CN1CC21
COC12CC1CN1CC12
false
CCC12CC1CC1CC12
C1C2CN3CC3C12
125.171
33.208
0.0893
2
0
124,435
3.32066
1.21628
1.10278
3.8731
67.22
-0.3044
-0.0463
0.2581
1,105.4794
0.102109
-429.038494
-429.03062
-429.029676
-429.072375
27.271
CC(C#N)N1N=CN=N1
CC(C#N)n1ncnn1
false
CCC(C)C1CCCC1
c1nn[nH]n1
123.119
28.141
-0.24232
5
0
10,930
5.65789
1.37798
1.27232
4.1378
69.47
-0.2707
0.0233
0.294
968.7758
0.131276
-342.764896
-342.757477
-342.756532
-342.796516
27.752
CC12CC(C#N)C1N2
CC12CC(C#N)C1N2
true
CCC1CC2(C)CC12
C1CC2NC12
108.144
29.0487
0.26038
2
1
23,874
3.06645
1.76273
1.42296
2.0789
40.76
-0.3327
-0.0105
0.3222
817.7646
0.055896
-544.965185
-544.957689
-544.956745
-544.99759
25.742
OC(C#N)C(F)(F)F
N#CC(O)C(F)(F)F
false
CCC(C)C(C)(C)C
125.049
17.6748
0.43318
2
1
26,671
2.3301
1.54277
0.9398
1.5951
77.03
-0.1563
0.0643
0.2206
1,223.6625
0.147875
-435.291222
-435.281182
-435.280238
-435.32555
36.686
CC1=C(N)C(N)=C(O)N1
Cc1[nH]c(O)c(N)c1N
false
CC1CC(C)C(C)C1C
c1cc[nH]c1
127.147
36.0193
0.19312
3
4
43,531
2.64402
1.46141
1.06174
2.4263
69.39
-0.267
-0.0088
0.2582
1,084.3976
0.100585
-432.834332
-432.826373
-432.825429
-432.867111
29.078
N=C1NC(C#N)C11CO1
N#CC1NC(=N)C12CO2
false
CCC1CC(C)C12CC2
N=C1NCC12CO2
123.115
28.9464
-0.77195
3
2
65,798
2.20924
1.65229
1.42415
4.7986
68.02
-0.2716
-0.0801
0.1915
972.3326
0.100641
-436.722749
-436.714844
-436.7139
-436.755484
29.109
OC1(CC=CC1=O)C#N
N#CC1(O)CC=CC1=O
false
CCC1(C)CCCC1C
O=C1C=CCC1
123.111
29.3268
-0.22992
3
1
81,100
2.13906
1.63832
1.22851
4.3173
63.19
-0.2533
-0.0406
0.2127
1,034.4338
0.109981
-494.821433
-494.813184
-494.81224
-494.854454
30.49
OC1C2OC1(C=O)C2O
O=CC12OC(C1O)C2O
false
CCC12CC(C1C)C2C
C1C2CC1O2
130.099
25.6816
-1.9417
4
2
118,954
2.97206
0.89654
0.85696
2.3234
81.46
-0.2428
0.0759
0.3187
1,504.3517
0.203746
-425.412054
-425.401458
-425.400514
-425.447969
38.727
CC1COC1(C)CCO
CC1COC1(C)CCO
true
CCCC1(C)CCC1C
C1COC1
130.187
35.2238
0.7938
2
1
80,259
2.28038
2.03398
1.56518
4.9118
68.31
-0.2298
-0.0135
0.2163
901.5145
0.126476
-437.907869
-437.900837
-437.899893
-437.93896
28.489
OC1C2NC(=O)C1C=C2
O=C1NC2C=CC1C2O
false
CC1CC2CCC1C2C
O=C1NC2C=CC1C2
125.127
30.5675
-0.9683
2
2
58,199
2.14286
1.11378
1.0221
3.0082
82.15
-0.2803
0.0295
0.3098
1,365.5258
0.191758
-404.377
-404.366042
-404.365098
-404.412998
39.862
CC(C)C(O)C(C)C#N
CC(C)C(O)C(C)C#N
true
CCC(C)C(C)C(C)C
127.187
35.6218
1.16298
2
1
17,303
3.2027
2.51699
1.91266
3.7994
59.98
-0.2356
0.0511
0.2867
730.4868
0.119094
-399.703373
-399.696974
-399.69603
-399.733476
25.712
OC12COC1C1NC21
OC12COC1C1NC12
false
CC12CCC1C1CC12
C1OC2C1C1NC12
113.116
25.4015
-1.5297
3
2
25,723
2.72523
1.60793
1.01762
2.953
72.63
-0.2277
-0.0492
0.1785
1,100.5664
0.112218
-457.826149
-457.818094
-457.81715
-457.859824
29.163
CC(=O)C1=C(O)C=CO1
CC(=O)c1occc1O
false
CC(C)C1CCCC1C
c1ccoc1
126.111
30.3773
1.1878
3
1
97,293
2.1911
1.30987
1.02715
4.2162
81.55
-0.2448
0.0016
0.2464
1,255.2377
0.145871
-398.112924
-398.103304
-398.10236
-398.147563
33.986
CN=CN1C(C)C1C#N
CN=CN1C(C)C1C#N
true
CCCC1C(C)C1CC
C1CN1
123.159
35.118
0.24078
2
0
81,947
2.38036
1.77642
1.192
4.3231
70.83
-0.2346
-0.0208
0.2139
1,054.4836
0.147646
-439.086186
-439.077656
-439.076712
-439.119594
32.073
CC1C2NC2C(O)C1=O
CC1C(=O)C(O)C2NC12
false
CC1C(C)C2CC2C1C
O=C1CC2NC2C1
127.143
30.8895
-1.0935
3
2
7,377
2.67667
1.61887
1.42893
4.4349
59.93
-0.2504
0.015
0.2654
964.5987
0.142583
-438.161526
-438.153044
-438.152099
-438.195028
30.431
C[NH2+]CC(O)C([O-])=O
C[NH2+]CC(O)C(=O)[O-]
false
CCCC(C)C(C)C
119.12
23.7302
-3.7096
3
2
6,161
3.38263
1.40353
1.28028
2.6287
77.08
-0.239
-0.0098
0.2292
1,082.5603
0.174542
-349.029619
-349.020316
-349.019372
-349.063213
34.365
CC(=O)C1CC1(C)C
CC(=O)C1CC1(C)C
true
CC(C)C1CC1(C)C
C1CC1
112.172
32.569
1.6215
1
0
11,281
5.26947
1.24131
1.07488
0.8997
74.12
-0.2514
0.0516
0.303
1,112.7093
0.153535
-347.78253
-347.774333
-347.773389
-347.815898
30.504
CC1CC(CO1)C#C
C#CC1COC(C)C1
false
CCC1CCC(C)C1
C1CCOC1
110.156
32.354
1.0446
1
0
46,354
3.33088
1.12343
0.88445
0.9781
76.19
-0.2367
-0.024
0.2127
1,310.1487
0.158591
-423.013467
-423.004776
-423.003832
-423.048472
31.198
O=C1CCC1C1CCO1
O=C1CCC1C1CCO1
true
CC1CCC1C1CCC1
O=C1CCC1C1CCO1
126.155
32.088
0.7544
2
0
123,421
4.97684
0.92704
0.84146
6.2668
76.45
-0.246
0.0196
0.2656
1,367.8438
0.149891
-398.127136
-398.119178
-398.118234
-398.161372
29.16
C(C1CC1)N1C=NN=C1
c1nncn1CC1CC1
false
C1CCC(CC2CC2)C1
c1nncn1CC1CC1
123.159
32.746
0.6881
3
0
125,308
3.17589
1.59253
1.07474
3.4796
77.8
-0.2242
-0.0192
0.205
1,073.7205
0.125855
-400.758092
-400.75097
-400.750026
-400.789509
27.79
CC1=CCC2=NOC=C12
CC1=CCc2nocc21
false
CC1CCC2CCCC12
C1=Cc2conc2C1
121.139
33.858
1.634
2
0
27,039
2.37832
1.4913
0.92184
7.1364
70.52
-0.2383
-0.0608
0.1775
1,177.1479
0.100412
-473.897794
-473.889686
-473.888741
-473.930756
29.021
CC1=C(OC(=O)N1)C=O
Cc1[nH]c(=O)oc1C=O
false
CCC1CC(C)CC1C
O=c1[nH]cco1
127.099
29.4532
0.08882
3
1
114,267
4.65849
1.07639
1.04243
2.4236
82.17
-0.2065
0.0645
0.2711
1,243.3745
0.169635
-402.99377
-402.985738
-402.984794
-403.026293
31.8
CCN1CC23CC(O2)C13
CCN1CC23CC(O2)C13
true
CCC1CC23CC(C2)C13
C1NC2C3CC12O3
125.171
33.256
0.2318
2
0
68,465
2.44799
2.02145
1.34853
3.1671
72.77
-0.2582
0.024
0.2823
965.9251
0.149839
-439.096818
-439.089508
-439.088564
-439.12823
29.826
OC12CC(C1)COC2=N
N=C1OCC2CC1(O)C2
false
CC1CCC2CC1(C)C2
N=C1OCC2CC1C2
127.143
31.3525
0.13497
3
2
115,771
2.60172
1.01946
0.78874
3.0033
78.32
-0.2548
0.0165
0.2713
1,481.3576
0.169464
-440.263563
-440.253764
-440.25282
-440.300191
34.131
CCC1OCC1OC=N
CCC1OCC1OC=N
true
CCCC1CCC1CC
C1COC1
129.159
33.6877
0.78747
3
1
84,797
2.72057
1.50576
1.10751
5.3831
68.42
-0.2377
0.0011
0.2388
1,082.6806
0.137564
-455.198685
-455.190514
-455.18957
-455.231921
30.421
CC1[NH+]=CNC1C([O-])=O
CC1[NH+]=CNC1C(=O)[O-]
false
CC(C)C1CCCC1C
C1=[NH+]CCN1
128.131
28.4194
-3.7945
3
2
85,544
2.46894
1.68554
1.08695
4.4386
73.01
-0.225
0.013
0.238
1,105.7202
0.147961
-439.08984
-439.081838
-439.080894
-439.122409
30.569
CN1CC(=O)OC2CC12
CN1CC(=O)OC2CC21
false
CC1CC(C)C2CC2C1
O=C1CNC2CC2O1
127.143
30.915
-0.3841
3
0
95,575
2.55475
1.60943
1.05079
1.0219
66.12
-0.2525
-0.0387
0.2138
1,081.3488
0.124549
-475.035243
-475.027159
-475.026215
-475.068945
29.589
OC1COC=NCC1=O
O=C1CN=COCC1O
false
CC1CCCCCC1C
O=C1CCOC=NC1
129.115
30.3248
-1.0251
4
1
123,480
5.17488
0.9331
0.87598
5.4847
74.53
-0.249
0.0052
0.2541
1,323.3609
0.138344
-414.152129
-414.14442
-414.143476
-414.185436
28.31
C(N1CC1)C1=CN=NN1
c1nn[nH]c1CN1CC1
false
C1CCC(CC2CC2)C1
c1nn[nH]c1CN1CC1
124.147
31.6597
-0.3797
3
1
60,466
4.80145
0.58674
0.55025
0.5357
83.69
-0.2412
0.0709
0.3121
2,077.0775
0.203179
-425.40304
-425.392327
-425.391382
-425.440015
38.74
CC(O)CCOC1CC1
CC(O)CCOC1CC1
true
CC(C)CCCC1CC1
C1CC1
130.187
35.2718
0.9363
2
1
8,874
3.33753
1.36406
1.14064
1.8566
62.72
-0.2501
-0.0974
0.1527
1,076.0729
0.126239
-420.877794
-420.868432
-420.867488
-420.912577
31.345
COC(C)C(=O)C=O
COC(C)C(=O)C=O
true
CCC(C)C(C)CC
116.116
27.542
-0.2107
3
0
27,583
3.64513
1.19914
0.90288
1.7344
86.97
-0.2174
-0.04
0.1774
1,217.2956
0.114275
-379.70839
-379.700682
-379.699737
-379.74034
30.215
NC1=CC(=CC=N1)C#C
C#Cc1ccnc(N)c1
false
CCC1CCCC(C)C1
c1ccncc1
118.139
36.5844
0.6451
2
1
103,406
2.50026
1.53059
1.33348
1.5019
61.06
-0.2408
-0.0408
0.2
994.1891
0.110537
-494.854042
-494.845806
-494.844862
-494.886929
30.622
OCC1(O)C2OC2C1=O
O=C1C2OC2C1(O)CO
false
CCC1(C)C(C)C2CC21
O=C1CC2OC12
130.099
25.7036
-1.9401
4
2
22,564
2.12825
1.51126
1.03841
1.0154
78.21
-0.2501
-0.002
0.248
1,212.9538
0.168609
-440.235
-440.225059
-440.224115
-440.269469
37.044
CC1C(C)C(=NO)C1O
CC1C(=NO)C(O)C1C
false
CCC1C(C)C(C)C1C
N=C1CCC1
129.159
33.5563
0.4633
3
2
19,597
4.28868
2.03926
1.89099
2.9538
58.92
-0.2462
0.0658
0.312
734.1007
0.121263
-399.721014
-399.715323
-399.714379
-399.750476
23.951
OC1C2NC1C1OC21
OC1C2NC1C1OC21
true
CC1C2CC1C1CC21
C1C2NC1C1OC21
113.116
25.3795
-1.5313
3
2
113,332
2.12678
1.25786
1.03524
4.0414
77.82
-0.2323
0.0257
0.258
1,271.4698
0.157766
-419.178669
-419.168774
-419.16783
-419.213554
35.443
CNC1(CC1OC)C#N
CNC1(C#N)CC1OC
false
CCC1CC1(CC)CC
C1CC1
126.159
32.8177
-0.11312
3
1
118,386
3.20641
0.78915
0.66522
3.0463
78.21
-0.2748
0.0276
0.3023
1,644.4239
0.145025
-401.923321
-401.912923
-401.911979
-401.959573
36.163
OCCC(CC#C)C#N
C#CCC(C#N)CCO
false
CCCC(CC)CCC
123.155
34.2558
0.53188
2
1
44,870
3.6307
1.69773
1.55116
3.545
59.21
-0.2618
-0.003
0.2588
848.3092
0.103827
-473.817258
-473.811411
-473.810467
-473.84745
23.905
O=C1OC2OC1C1NC21
O=C1OC2OC1C1NC21
true
CC1CC2CC1C1CC21
O=C1OC2OC1C1NC21
127.099
25.4647
-1.3915
4
1
60,093
3.39399
0.95112
0.8787
0.1469
93.59
-0.2825
0.0823
0.3649
1,489.6894
0.229152
-352.319079
-352.309574
-352.30863
-352.353944
37.054
CC(C)CC12CC(C1)C2
CC(C)CC12CC(C1)C2
true
CC(C)CC12CC(C1)C2
C1C2CC1C2
124.227
39.229
2.8326
0
0
129,757
3.2025
1.43323
1.05469
3.9035
65.74
-0.2211
-0.0377
0.1834
1,065.9456
0.10098
-469.949967
-469.942355
-469.941411
-469.982573
28.012
NC1=C(ON=N1)C1CO1
Nc1nnoc1C1CO1
false
CC1CCCC1C1CC1
c1nnoc1C1CO1
127.103
27.4034
-0.2769
5
1
95,590
2.50357
1.51411
1.08914
0.8836
86.08
-0.2306
0.0104
0.241
1,185.0036
0.183277
-387.086661
-387.077991
-387.077047
-387.120135
33.718
CC1OCC=CCC=C1
CC1C=CCC=CCO1
false
CC1CCCCCCC1
C1=CCOCC=CC1
124.183
38.311
1.9076
1
0
21,930
7.01545
1.30138
1.10568
4.4744
55.37
-0.2289
0.018
0.2469
988.1744
0.097008
-431.940321
-431.932888
-431.931944
-431.97306
26.087
OCC1=NC(O)=NN1
OCc1nc(O)n[nH]1
false
CCC1CCC(C)C1
c1nc[nH]n1
115.092
23.9703
-0.9974
4
3
2,994
7.03182
1.52911
1.40342
2.4043
61.98
-0.2556
-0.0214
0.2342
897.8985
0.136271
-325.775843
-325.768181
-325.767237
-325.808102
26.782
CCC(=O)C1CN1
CCC(=O)C1CN1
true
CCC(C)C1CC1
C1CN1
99.133
27.0887
-0.0627
2
1
77,678
1.87064
1.6202
1.58464
1.5951
78.26
-0.2448
0.0709
0.3157
1,077.3038
0.181694
-424.220617
-424.211262
-424.210317
-424.25384
35.795
CC1C2(C)COCC12O
CC1C2(C)COCC12O
true
CC1C2(C)CCCC12C
C1OCC2CC12
128.171
33.0398
0.4037
2
1
62,461
3.82432
1.1866
1.16862
2.0896
75.36
-0.2412
0.0292
0.2703
1,106.0182
0.134769
-421.770444
-421.761999
-421.761055
-421.803245
31.966
OC1(C#C)C2COCC12
C#CC1(O)C2COCC21
false
CCC1(C)C2CCCC21
C1OCC2CC12
124.139
31.5818
-0.3731
2
1
85,498
2.51035
1.26142
0.96481
2.0696
75.64
-0.2482
-0.0361
0.212
1,242.0777
0.157501
-423.072426
-423.063313
-423.062369
-423.107118
33.231
CC1CC(=O)CC1C=O
CC1CC(=O)CC1C=O
true
CCC1CC(C)CC1C
O=C1CCCC1
126.155
32.959
0.8005
2
0
95,990
2.85752
1.26311
1.05168
4.7354
75.19
-0.2475
0.018
0.2655
1,202.773
0.172518
-440.341051
-440.331906
-440.330962
-440.375964
33.946
NC(=O)C1CCCC1O
NC(=O)C1CCCC1O
true
CC(C)C1CCCC1C
C1CCCC1
129.159
32.5422
-0.3673
2
2
56,003
3.7939
0.96815
0.86488
2.8157
73.01
-0.2401
-0.0111
0.229
1,346.0298
0.147252
-439.120089
-439.111147
-439.110202
-439.155357
31.366
CC(=O)CC1COC=N1
CC(=O)CC1COC=N1
true
CC(C)CC1CCCC1
C1=NCCO1
127.143
33.53
0.3926
3
0
52,128
5.05997
0.6615
0.61639
2.6944
87.04
-0.2337
-0.021
0.2126
1,812.7346
0.182142
-387.120627
-387.111155
-387.110211
-387.15664
33.723
O=CCCC1=CCCC1
O=CCCC1=CCCC1
true
CCCCC1CCCC1
C1=CCCC1
124.183
37.232
2.0758
1
0
58,372
2.61596
1.03466
0.88188
3.7802
77.92
-0.2778
0.0256
0.3034
1,361.8117
0.144759
-401.932792
-401.922657
-401.921712
-401.968107
36.508
CC(O)C(CC#N)C#C
C#CC(CC#N)C(C)O
false
CCCC(CC)C(C)C
123.155
34.2338
0.53028
2
1
77,652
2.22058
1.48271
1.31656
4.3554
64.32
-0.2579
-0.0183
0.2396
1,021.5111
0.099008
-473.769673
-473.761268
-473.760324
-473.802678
30.618
OC1C2(O)COC12C#N
N#CC12OCC1(O)C2O
false
CCC12CCC1(C)C2C
C1OC2CC12
127.099
25.2526
-1.61542
4
2
54,347
2.00284
1.83142
1.18048
3.0132
69.39
-0.2532
-0.0097
0.2435
1,058.1182
0.125156
-434.087824
-434.07911
-434.078166
-434.12159
31.804
NC(=O)C1(CCN1)C#N
N#CC1(C(N)=O)CCN1
false
CCC1(C(C)C)CCC1
C1CNC1
125.131
30.1581
-1.27262
3
2
129,476
4.44634
1.02682
0.89219
2.1776
60.66
-0.2644
-0.0852
0.1792
1,206.3028
0.088857
-486.04252
-486.034684
-486.03374
-486.076231
27.644
NC(=O)CC1=NON=N1
NC(=O)Cc1nnon1
false
CC(C)CC1CCCC1
c1nnon1
128.091
24.9914
-1.5076
5
1
125,363
3.37987
1.63532
1.10967
4.1197
74.18
-0.2128
-0.0068
0.2059
1,028.1114
0.115802
-413.000549
-412.993273
-412.992329
-413.032095
27.792
CC1=CNC2=C1NN=N2
Cc1c[nH]c2nn[nH]c12
false
CC1CCC2CCCC12
c1cc2[nH]nnc2[nH]1
122.131
32.9764
0.59442
2
2
63,468
2.61428
1.31614
1.04713
1.2466
86.08
-0.2406
0.0759
0.3165
1,265.3561
0.2032
-388.265426
-388.255215
-388.254271
-388.29997
39.313
CC1(O)CC1(C)C1CC1
CC1(O)CC1(C)C1CC1
true
CC1(C)CC1(C)C1CC1
C1CC1C1CC1
126.199
36.0718
1.5574
1
1
105,173
1.73758
1.28493
0.81929
1.8957
85.55
-0.2394
0.041
0.2803
1,475.6123
0.1683
-403.099052
-403.088239
-403.087295
-403.136504
37.736
CC#CC1(CO)NC1C
CC#CC1(CO)NC1C
true
CCCC1(CC)CC1C
C1CN1
125.171
35.8645
-0.2675
2
2
105,089
2.55431
1.16016
1.07266
1.3367
82.16
-0.2224
0.0642
0.2866
1,273.1834
0.193291
-404.287706
-404.277982
-404.277038
-404.322236
36.844
OCC1(CC1)C1CN1C
CN1CC1C1(CO)CC1
false
CCC1(C2CC2C)CC1
C1CC1C1CN1
127.187
35.1708
0.0729
2
1
83,332
2.15474
1.67632
1.51357
1.8253
70.19
-0.2383
0.0551
0.2934
1,007.9089
0.159201
-460.135374
-460.126981
-460.126037
-460.167622
33.199
CC12COC(C1O)C2O
CC12COC(C1O)C2O
true
CC1C2CCC1(C)C2C
C1OC2CC1C2
130.143
29.8606
-0.8731
3
2
121,631
2.3422
0.93167
0.82944
2.2006
82.68
-0.2314
-0.0146
0.2168
1,574.2571
0.201947
-425.444825
-425.433403
-425.432459
-425.482647
39.973
CCOCC(=O)C(C)C
CCOCC(=O)C(C)C
true
CCCCC(C)C(C)C
130.187
36.338
1.248
2
0
9,932
3.0543
1.49775
1.40918
1.8272
75.11
-0.2353
0.0508
0.2861
1,003.0075
0.150443
-347.757634
-347.748207
-347.747263
-347.790979
34.695
CC1C(O)C1(C)C#C
C#CC1(C)C(C)C1O
false
CCC1(C)C(C)C1C
C1CC1
110.156
32.1108
0.6365
1
1
81,008
2.51105
1.53109
1.23477
1.7742
77.83
-0.2409
0.0725
0.3134
1,117.8266
0.181947
-424.215455
-424.206591
-424.205647
-424.248193
34.991
CC1C2OC1(C)CC2O
CC1C2OC1(C)CC2O
true
CC1CC2(C)CC1C2C
C1CC2CC1O2
128.171
33.0658
0.5446
2
1
123,844
3.71191
1.66853
1.18533
3.2055
76.66
-0.2324
-0.0264
0.206
991.2068
0.129062
-396.977183
-396.970684
-396.96974
-397.008087
25.618
C1CC2=NC=NN2C=C1
C1=Cn2ncnc2CC1
false
C1CCC2CCCC2C1
C1=Cn2ncnc2CC1
121.143
33.673
0.695
3
0
114,275
4.26328
1.14245
1.10363
2.457
76.64
-0.2445
0.0568
0.3013
1,158.0165
0.159829
-422.876569
-422.868998
-422.868054
-422.908579
30.6
OCC1OC23CC(C2)C13
OCC1OC23CC(C2)C13
true
CCC1CC23CC(C2)C13
C1OC23CC(C2)C13
126.155
30.9038
0.1561
2
1
24,878
3.37845
1.31714
0.94767
3.2369
87.37
-0.2148
-0.068
0.1468
1,157.3329
0.101147
-399.5495
-399.541988
-399.541044
-399.581591
28.747
N=C1OC(=CC=C1)C#C
C#Cc1cccc(=N)o1
false
CCC1CCCC(C)C1
N=c1cccco1
119.123
32.4977
0.74037
2
1
8,480
2.85349
1.95781
1.59453
1.82
68.33
-0.2217
0.0614
0.2831
893.9433
0.15251
-384.909707
-384.901525
-384.900581
-384.941684
31.602
CC12CC1(O)C(O)C2
CC12CC(O)C1(O)C2
false
CC1CC2(C)CC12C
C1CC2CC12
114.144
28.2976
-0.1079
2
2
129,380
2.77692
1.47386
0.99801
2.599
69.64
-0.2422
-0.0256
0.2166
1,118.1275
0.115208
-450.129304
-450.121399
-450.120455
-450.161746
30.299
NC(=N)C1=CON=C1N
N=C(N)c1conc1N
false
CC(C)C1CCCC1C
c1cnoc1
126.119
31.9315
-0.45913
4
3
6,643
8.50246
0.73706
0.68394
4.6788
69.92
-0.264
-0.0614
0.2026
1,550.4521
0.102761
-382.536847
-382.527463
-382.526519
-382.574133
29.864
CC(=O)CC#CC=O
CC(=O)CC#CC=O
true
CCCCCC(C)C
110.112
29.138
0.1678
2
0
79,472
2.55822
1.87395
1.48916
1.1663
66.21
-0.2263
0.0695
0.2958
918.7759
0.136657
-458.91012
-458.90295
-458.902006
-458.941215
29.457
OC1C2C3CC1(O)C2O3
OC1C2C3CC1(O)C2O3
true
CC1C2C3CC2C1(C)C3
C1C2CC3C1OC23
128.127
27.7246
-1.1207
3
2
74,072
2.67785
1.53709
1.12909
5.711
81.13
-0.2142
-0.0165
0.1977
1,105.8951
0.14824
-401.986881
-401.978442
-401.977498
-402.019368
32.934
CC12CC1C(N)=CC2=O
CC12CC1C(N)=CC2=O
true
CC1CC(C)C2(C)CC12
O=C1C=CC2CC12
123.155
33.4914
0.4379
2
1
98,797
2.91701
1.14707
0.91088
2.5283
73.83
-0.2488
-0.0207
0.2282
1,304.6674
0.146307
-439.132401
-439.122976
-439.122031
-439.167675
33.127
CCC(=O)C1CNC1=O
CCC(=O)C1CNC1=O
true
CCC(C)C1CCC1C
O=C1CCN1
127.143
31.7977
-0.2885
2
1
123,790
5.00552
0.94341
0.8476
2.659
78.59
-0.1838
0.0315
0.2153
1,357.8376
0.149819
-398.116637
-398.108358
-398.107413
-398.150452
31.136
C1CC1NC1=CNN=C1
c1n[nH]cc1NC1CC1
false
C1CCC(CC2CC2)C1
c1n[nH]cc1NC1CC1
123.159
35.2324
0.984
2
2
78,759
2.55271
1.55992
1.26594
0.906
74.76
-0.2492
0.0691
0.3182
1,063.9622
0.157948
-422.975963
-422.967453
-422.966509
-423.008293
33.911
CC12CC3(O)C(C13)C2O
CC12CC3(O)C(C1O)C23
false
CC1C2C3C1(C)CC23C
C1C2CC3C1C23
126.155
30.6606
-0.252
2
2
90,982
2.69542
1.83071
1.32983
3.1436
73.88
-0.2233
0.0674
0.2908
995.9547
0.159147
-422.967567
-422.959758
-422.958813
-422.999432
31.365
CC1CC2C3OC2C13O
CC1CC2C3OC2C13O
true
CC1CC2C3CC2C13C
C1CC2C3OC2C13
126.155
30.8818
0.1545
2
1
89,395
2.67277
1.47681
1.18012
2.2896
76.17
-0.2384
-0.0205
0.2179
1,119.8966
0.157705
-423.045924
-423.037168
-423.036224
-423.079209
33.314
CC1OC2(C)CC2C1=O
CC1OC2(C)CC2C1=O
true
CC1CC2(C)CC2C1C
O=C1COC2CC12
126.155
32.066
0.7528
2
0
12,737
2.58082
2.15395
1.7527
1.7048
74.36
-0.2351
0.0777
0.3128
898.2653
0.176551
-348.983916
-348.975829
-348.974885
-349.016078
31.115
CC1OC2CCC12C
CC1OC2CCC12C
true
CC1CC2CCC12C
C1CC2OCC12
112.172
31.676
1.5738
1
0
67,711
2.10691
1.91478
1.64735
1.2913
79.95
-0.2399
0.077
0.3169
986.2934
0.185892
-387.10126
-387.09381
-387.092865
-387.132697
31.156
OC12C3CCC1CCC23
OC12C3CCC1C2CC3
false
CC12C3CCC1C2CC3
C1CC2C3CCC1C23
124.183
33.8878
1.1673
1
1
130,123
3.18159
1.4157
0.98072
3.0248
75.2
-0.1859
-0.0324
0.1535
1,125.85
0.114794
-450.141339
-450.133429
-450.132485
-450.17339
31.098
NC1=NNC(=N)C=C1O
N=c1cc(O)c(N)n[nH]1
false
CC1CCC(C)C(C)C1
N=c1cccn[nH]1
126.119
30.5196
-0.82303
4
4
84,810
2.836
1.42341
1.11325
2.413
75.49
-0.2499
0.0144
0.2643
1,123.7463
0.160037
-423.007799
-422.999561
-422.998616
-423.040924
31.532
OC1C=CCC1C1CO1
OC1C=CCC1C1CO1
true
CC1CCCC1C1CC1
C1=CCC(C2CO2)C1
126.155
32.9938
0.3222
2
1
39,697
3.84611
1.68476
1.55008
1.9246
74.04
-0.2235
0.0667
0.2901
892.3542
0.138769
-380.774206
-380.768076
-380.767131
-380.804441
26.132
C1NC11C2C3C2N2C3C12
C1NC12C1C3C1N1C3C12
false
C1CC12C1C3C1C1C3C12
C1NC12C1C3C1N1C3C12
120.155
30.9167
-0.977
2
1
32,476
3.14483
1.16062
0.8814
2.5389
74.72
-0.182
0.0426
0.2245
1,308.5526
0.134588
-455.146788
-455.137321
-455.136377
-455.181915
32.893
COC1=CNC(O1)=NC
CN=c1[nH]cc(OC)o1
false
CCC1CCC(CC)C1
N=c1[nH]cco1
128.131
31.0977
0.1468
3
1
11,140
4.96773
1.51699
1.28657
3.068
68.44
-0.2563
-0.0375
0.2188
914.3501
0.095493
-361.443065
-361.436211
-361.435267
-361.474265
25.698
N=C1OC(C=C1)C#C
C#CC1C=CC(=N)O1
false
CCC1CCC(C)C1
N=C1C=CCO1
107.112
30.5727
0.55187
2
1
3,248
5.95067
2.33797
2.117
1.8479
60.81
-0.2488
0.0873
0.3361
660.044
0.125282
-308.457113
-308.451203
-308.450259
-308.486567
23.262
C1CC11CC2OC12
C1CC12CC1OC12
false
C1C2CC3(CC3)C12
C1CC12CC1OC12
96.129
24.945
0.9377
1
0
72,002
2.7216
1.6409
1.18861
3.2376
77.45
-0.2467
-0.0311
0.2156
1,057.8853
0.147246
-401.909346
-401.901352
-401.900408
-401.941773
30.582
CC12CC3CC1(C=O)N23
CC12CC3CC1(C=O)N32
false
CCC12CC3CC1(C)C32
C1C2CC3C1N23
123.155
32.061
0.1744
2
0
100,481
5.21729
0.57989
0.54457
1.3547
80.64
-0.2458
0.0102
0.2561
1,984.8396
0.146699
-439.014266
-439.004441
-439.003497
-439.050775
34.695
OCC(O)C#CC1CN1
OCC(O)C#CC1CN1
true
CCC(C)CCC1CC1
C1CN1
127.143
32.6593
-1.6852
3
3
86,230
2.04058
1.47161
0.99188
3.0469
72.35
-0.2752
0.0141
0.2893
1,222.3039
0.147174
-439.102662
-439.093628
-439.092684
-439.137598
32.937
CC1CC(O)C(O1)C#N
CC1CC(O)C(C#N)O1
false
CCC1CC(C)CC1C
C1CCOC1
127.143
30.5718
0.04828
3
1
38,721
2.55506
2.02624
1.58137
0.8416
77.24
-0.2296
0.0804
0.3101
925.7549
0.175008
-403.109306
-403.102569
-403.101625
-403.13989
29.015
C1C2NC22CC1OCC2
C1CC23CC(CC2N3)O1
false
C1CC2CC3CC3(C1)C2
C1CC23CC(CC2N3)O1
125.171
33.2457
0.2797
2
1
48,957
3.20921
1.65809
1.40893
2.5055
72.31
-0.2497
-0.0359
0.2138
939.4892
0.136918
-421.789915
-421.783036
-421.782092
-421.821384
27.319
O=CC12CC3OC1CC23
O=CC12CC3OC1CC32
false
CCC12CC3CC1CC32
C1C2OC3CC2C13
124.139
29.882
0.3627
2
0
111,234
3.21104
1.15703
1.07124
1.438
84.98
-0.2448
0.0866
0.3313
1,268.2207
0.208039
-388.284062
-388.275631
-388.274687
-388.316998
33.326
CCC1C2CC1COC2
CCC1C2COCC1C2
false
CCC1C2CCCC1C2
C1OCC2CC1C2
126.199
36.197
1.6789
1
0