index
int64
1
134k
A
float64
0
620k
B
float64
0.34
438
C
float64
0.33
283
mu
float64
0
29.6
alpha
float64
6.31
197
homo
float64
-0.43
-0.1
lumo
float64
-0.18
0.19
gap
float64
0.02
0.62
r2
float64
19
3.37k
zpve
float64
0.02
0.27
U0
float64
-714.57
-40.48
U
float64
-714.56
-40.48
H
float64
-714.56
-40.48
G
float64
-714.6
-40.5
Cv
float64
6
47
smiles
stringlengths
1
28
canonsmiles
stringlengths
1
34
isSmilesEqual
bool
2 classes
generic_scaffold
stringlengths
1
21
scaffold
stringlengths
0
31
rdkit_WT
float64
16
152
rdkit_MR
float64
3.61
43.7
rdkit_LogP
float64
-4.91
3.76
rdkit_HA
float64
0
7
rdkit_HD
float64
0
5
100,328
2.14123
1.16665
0.99614
1.5503
87.53
-0.249
0.0551
0.3041
1,373.0297
0.201263
-388.254445
-388.243035
-388.24209
-388.290775
41.718
CCC(C)(CC#C)OC
C#CCC(C)(CC)OC
false
CCCC(C)(CC)CC
126.199
39.155
1.8248
1
0
48,824
2.6984
1.61208
1.16607
3.5643
65.78
-0.2657
-0.0442
0.2215
1,020.0536
0.11287
-457.805504
-457.797942
-457.796997
-457.837853
27.77
O=CC12CC1COC2=O
O=CC12CC1COC2=O
true
CCC12CC1CCC2C
O=C1OCC2CC12
126.111
27.563
-0.2516
3
0
18,530
5.40153
1.15237
1.07143
1.2202
68.22
-0.2357
0.0712
0.3069
1,148.5804
0.15289
-384.877095
-384.869092
-384.868147
-384.910153
29.011
COCC1OC2CC12
COCC1OC2CC12
true
CCCC1CC2CC12
C1OC2CC12
114.144
28.644
0.4201
2
0
25,807
3.90931
1.1236
0.87754
4.1016
76.32
-0.2251
-0.0244
0.2006
1,273.1803
0.123995
-437.964788
-437.955837
-437.954893
-437.999155
31.705
CC1=CC=C(O1)C(N)=O
Cc1ccc(C(N)=O)o1
false
CC1CCC(C(C)C)C1
c1ccoc1
125.127
31.9629
0.68692
2
1
131,713
2.08138
1.81304
1.00963
3.35
65.57
-0.282
-0.0649
0.2171
1,094.7334
0.102069
-470.031886
-470.024019
-470.023075
-470.064904
27.683
OCC1=NC=NN1C=O
O=Cn1ncnc1CO
false
CCC1CCCC1CC
c1nc[nH]n1
127.103
28.0933
-1.1913
5
1
32,591
2.88638
1.22463
0.92886
2.2336
78.92
-0.1932
0.0552
0.2485
1,308.1858
0.159496
-419.263835
-419.254444
-419.2535
-419.298553
34.234
CCN1C=C(C)N=C1O
CCn1cc(C)nc1O
false
CCC1CC(C)CC1C
c1c[nH]cn1
126.159
34.3028
0.91702
3
1
86,245
2.74558
1.25485
1.03747
1.17
71.53
-0.2423
-0.0337
0.2086
1,203.2388
0.157464
-460.176666
-460.167408
-460.166464
-460.211428
33.781
CC1CC(O)C(O1)C=O
CC1CC(O)C(C=O)O1
false
CCC1CC(C)CC1C
C1CCOC1
130.143
31.0228
-0.2764
3
1
111,061
1.91029
1.65868
1.086
2.9676
82.94
-0.2218
0.0619
0.2837
1,218.5861
0.194476
-404.26515
-404.255913
-404.254968
-404.29914
35.2
CCC1N2CC1(CO)C2
CCC1N2CC1(CO)C2
true
CCC1C2CC1(CC)C2
C1C2CN1C2
127.187
35.1708
0.0729
2
1
104,894
2.12691
1.40729
1.11012
1.9025
73.61
-0.2417
0.0684
0.3101
1,203.4396
0.182557
-461.362921
-461.35335
-461.352406
-461.397786
35.493
OCC1(CO)CCCO1
OCC1(CO)CCCO1
true
CCC1(CC)CCCC1
C1CCOC1
132.159
32.0886
-0.4798
3
2
63,695
2.52931
1.48642
1.19683
1.6574
85.18
-0.2358
0.0815
0.3173
1,174.607
0.204121
-388.274311
-388.264857
-388.263912
-388.30823
36.987
CC1(C)CC2(C)OCC12
CC1(C)CC2(C)OCC12
true
CC1(C)CC2(C)CCC12
C1CC2OCC12
126.199
36.245
1.8214
1
0
72,867
3.32531
1.28949
1.0916
3.0099
75.71
-0.241
-0.0256
0.2155
1,147.4348
0.157722
-423.006256
-422.997637
-422.996693
-423.039855
32.099
CC12CC(C=O)C1CO2
CC12CC(C=O)C1CO2
true
CCC1CC2(C)CCC12
C1CC2OCC12
126.155
32.018
0.6103
2
0
100,381
2.33175
1.11356
0.97557
2.858
78.41
-0.2473
-0.0265
0.2208
1,309.1365
0.153626
-422.987606
-422.976813
-422.975869
-423.023935
38.003
COC(C)(CC=O)C#C
C#CC(C)(CC=O)OC
false
CCCC(C)(CC)CC
126.155
34.928
0.6137
2
0
2,053
5.00787
2.70344
1.79408
4.2092
55.68
-0.2625
0.0034
0.2659
666.0868
0.102698
-344.494711
-344.488505
-344.487561
-344.525889
21.89
O=C1CC=CCO1
O=C1CC=CCO1
true
CC1CCCCC1
O=C1CC=CCO1
98.101
24.716
0.4895
2
0
105,269
2.53073
1.26925
1.07491
2.2248
79.58
-0.2241
0.0717
0.2958
1,239.8758
0.180501
-424.170398
-424.160751
-424.159807
-424.204775
36.438
COC1(CC1O)C1CC1
COC1(C2CC2)CC1O
false
CCC1(C2CC2)CC1C
C1CC1C1CC1
128.171
33.0878
0.5462
2
1
107,376
3.19257
1.30708
1.05057
3.8561
64.6
-0.256
0.0413
0.2973
1,118.0953
0.124845
-475.047439
-475.039504
-475.03856
-475.080215
30.007
OCC12CC1NC(=O)O2
O=C1NC2CC2(CO)O1
false
CCC12CC(C)CC1C2
O=C1NC2CC2O1
129.115
27.8385
-0.7704
3
2
66,606
4.17916
1.63916
1.51825
1.6998
78.84
-0.2125
0.0087
0.2212
924.1626
0.149812
-364.74917
-364.742575
-364.741631
-364.779677
27.711
CC12C3C1C1C=CC3N21
CC12C3C4C=CC(C31)N42
false
CC12C3C4CCC3C1C42
C1=CC2C3C4C1N2C43
119.167
33.94
0.6273
1
0
113,011
2.23436
1.24332
1.19517
1.9762
71.44
-0.2545
-0.0394
0.2151
1,172.374
0.158101
-460.150413
-460.141091
-460.140147
-460.184915
33.966
OCC1CC(C=O)C1O
O=CC1CC(CO)C1O
false
CCC1CC(CC)C1C
C1CCC1
130.143
30.7536
-0.8254
3
2
42,262
3.07428
1.18572
1.01522
4.5005
71.66
-0.2797
-0.071
0.2087
1,146.3069
0.087177
-415.564508
-415.555969
-415.555024
-415.598385
29.912
O=C(C#N)N1CC1C#C
C#CC1CN1C(=O)C#N
false
CCC(C)C1CC1CC
C1CN1
120.111
29.947
-0.64602
2
0
84,137
2.91685
1.15909
0.91599
0.8505
91.25
-0.2326
0.026
0.2586
1,343.2608
0.181276
-349.947302
-349.937742
-349.936798
-349.981317
36.464
CC1C=C(C)CC1C#C
C#CC1CC(C)=CC1C
false
CCC1CC(C)CC1C
C1=CCCC1
120.195
39.861
2.2219
0
0
50,311
3.2043
1.45057
1.11265
6.2508
70.62
-0.247
-0.0284
0.2187
1,066.5865
0.125491
-437.933727
-437.926126
-437.925181
-437.966202
28.234
O=CN1CC2CC2C1=O
O=CN1CC2CC2C1=O
true
CCC1CC2CC2C1C
O=C1NCC2CC12
125.127
29.374
-0.3789
2
0
28,581
4.02974
1.10303
0.92374
1.8171
73.6
-0.2331
-0.0072
0.2259
1,250.7566
0.124366
-437.901812
-437.89376
-437.892815
-437.935228
28.838
CC1=NC=C(O1)C1CO1
Cc1ncc(C2CO2)o1
false
CC1CCC(C2CC2)C1
c1ncc(C2CO2)o1
125.127
29.933
1.05432
3
0
120,830
2.48874
0.93441
0.75069
3.9484
77.56
-0.2356
-0.0169
0.2188
1,547.5602
0.167786
-440.240408
-440.230205
-440.229261
-440.277112
35.024
COCC1CN1CC=O
COCC1CN1CC=O
true
CCCC1CC1CCC
C1CN1
129.159
33.301
-0.4841
3
0
23,615
2.11449
1.15427
0.82685
2.5514
78.64
-0.2179
-0.0976
0.1203
1,390.2225
0.133843
-455.040158
-455.03074
-455.029796
-455.075437
33.01
[O-]N=C(C1C[NH2+]1)C1CO1
[O-]N=C(C1C[NH2+]1)C1CO1
true
CCC(C1CC1)C1CC1
N=C(C1C[NH2+]1)C1CO1
128.131
31.1224
-1.7304
3
1
13,283
6.66481
0.85025
0.7994
1.3983
72.37
-0.2445
0.0775
0.322
1,476.0829
0.175936
-386.113203
-386.10406
-386.103116
-386.148356
31.514
CCOCC1CCO1
CCOCC1CCO1
true
CCCCC1CCC1
C1COC1
116.16
30.85
0.8118
2
0
128,490
1.97016
1.79642
0.99992
3.1247
75.79
-0.2354
-0.0004
0.235
1,200.8662
0.14539
-439.081472
-439.071785
-439.070841
-439.116519
33.644
COC1=C(C)ON=C1C
COc1c(C)noc1C
false
CCC1C(C)CCC1C
c1cnoc1
127.143
32.529
1.30004
3
0
118,122
3.54075
0.74996
0.67716
1.289
86.87
-0.2244
0.0709
0.2953
1,784.0971
0.215184
-405.518495
-405.507432
-405.506488
-405.555116
39.997
CCCC(O)C1CN1C
CCCC(O)C1CN1C
true
CCCC(C)C1CC1C
C1CN1
129.203
37.3328
0.4614
2
1
40,216
2.94631
1.51162
1.15691
2.9299
72.87
-0.2459
0.0121
0.258
1,070.8149
0.148874
-439.064124
-439.056244
-439.0553
-439.096999
29.79
C1OC11CCN=COC1
C1=NCCC2(CO1)CO2
false
C1CCCC2(CC1)CC2
C1=NCCC2(CO1)CO2
127.143
32.611
0.204
3
0
58,280
2.55414
1.08103
0.9177
5.2136
78.98
-0.2396
0.0236
0.2631
1,380.9811
0.192572
-441.513992
-441.503635
-441.502691
-441.549777
37.983
CC(C)[NH+](C)CC([O-])=O
CC(C)[NH+](C)CC(=O)[O-]
false
CC(C)CC(C)C(C)C
131.175
31.8967
-2.3406
2
1
11,318
4.85717
1.58364
1.2031
2.4836
67.47
-0.2745
-0.0877
0.1869
938.4249
0.09572
-398.654344
-398.647372
-398.646428
-398.685906
24.883
CN=C1OC(=O)C=C1
CN=C1C=CC(=O)O1
false
CCC1CCC(C)C1
N=C1C=CC(=O)O1
111.1
28.591
0.1277
3
0
90,642
3.84436
1.10014
1.01854
2.8277
74.6
-0.2517
0.0165
0.2682
1,204.0252
0.13546
-417.971252
-417.962666
-417.961722
-418.004161
32.362
CC1OC2C1C2(N)C#N
CC1OC2C1C2(N)C#N
true
CCC1(C)C2CC(C)C21
C1OC2CC12
124.143
30.3564
-0.37542
3
1
90,719
4.03666
1.11114
1.01282
1.8826
82.42
-0.254
0.0727
0.3267
1,255.9815
0.182325
-387.046545
-387.038221
-387.037277
-387.079676
32.725
CC1CC2C1CC21CO1
CC1CC2C1CC21CO1
true
CC1CC2C1CC21CC1
C1CC2C1CC21CO1
124.183
34.061
1.4313
1
0
12,059
4.55055
1.61886
1.50379
2.9867
58.3
-0.2579
-0.0471
0.2108
839.5593
0.105343
-419.636223
-419.629225
-419.628281
-419.667422
26.35
OC1(CC2OC12)C=O
O=CC1(O)CC2OC21
false
CCC1(C)CC2CC21
C1CC2OC12
114.1
24.2918
-0.9125
3
1
51,259
4.86029
0.90037
0.83171
2.9654
79.13
-0.2235
-0.0328
0.1907
1,375.9641
0.147473
-401.935119
-401.926926
-401.925982
-401.969266
30.21
O=CCC1=CC2CN2C1
O=CCC1=CC2CN2C1
true
CCCC1CC2CC2C1
C1=CC2CN2C1
123.155
34.125
0.1996
2
0
120,269
3.08396
1.06768
0.9359
2.5848
79.16
-0.2406
0.0809
0.3215
1,358.7941
0.180426
-424.180485
-424.170961
-424.170017
-424.215376
34.827
CCOC1C2OC2C1C
CCOC1C(C)C2OC12
false
CCCC1C(C)C2CC12
C1CC2OC12
128.171
33.239
0.8086
2
0
38,979
2.90642
1.70429
1.24564
0.7433
78.71
-0.2436
0.0882
0.3319
1,039.4897
0.174112
-403.117017
-403.109837
-403.108893
-403.148339
29.618
C1C2NC22CCCOC12
C1COC2CC3NC32C1
false
C1CCC23CC2CC3C1
C1COC2CC3NC32C1
125.171
33.2457
0.2797
2
1
817
5.88512
1.90585
1.51808
0.9192
63.6
-0.2369
0.0136
0.2505
805.7743
0.137803
-325.758431
-325.751655
-325.750711
-325.789148
25.597
ON=C1CCCC1
ON=C1CCCC1
true
CCC1CCCC1
N=C1CCCC1
99.133
27.6895
1.3906
2
1
66,155
4.19005
0.69818
0.68034
1.3998
86.33
-0.2526
0.0757
0.3284
1,771.0985
0.204594
-388.263177
-388.253298
-388.252353
-388.298706
37.452
OC1(CCC2CC2)CC1
OC1(CCC2CC2)CC1
true
CC1(CCC2CC2)CC1
C1CC1CCC1CC1
126.199
36.1418
1.7015
1
1
28,693
3.41518
1.06508
0.84117
0.752
77.58
-0.1802
0.0473
0.2276
1,317.3125
0.12368
-400.747792
-400.739046
-400.738102
-400.781668
32.722
OC1=CC=C(CC#C)N1
C#CCc1ccc(O)[nH]1
false
CCCC1CCC(C)C1
c1cc[nH]c1
121.139
34.9945
0.896
1
2
48,024
5.03098
0.65011
0.62898
2.9816
81.47
-0.2655
-0.0626
0.2029
1,744.5973
0.135821
-421.805967
-421.796912
-421.795968
-421.842789
30.565
O=CC#CC1CCOC1
O=CC#CC1CCOC1
true
CCCCC1CCCC1
C1CCOC1
124.139
32.766
0.2252
2
0
83,475
3.16071
1.03918
0.94495
2.1626
68.75
-0.2442
-0.0305
0.2137
1,259.6618
0.133866
-458.913331
-458.904696
-458.903752
-458.9477
31.301
OC1C2OCC12CC=O
O=CCC12COC1C2O
false
CCCC12CCC1C2C
C1OC2CC12
128.127
28.8608
-0.6649
3
1
69,203
2.78585
1.5705
1.15718
4.0694
75.29
-0.2437
-0.0563
0.1874
1,070.9114
0.135784
-421.849877
-421.842033
-421.841089
-421.882065
30.232
CC12CC=CC(=O)C1O2
CC12CC=CC(=O)C1O2
true
CC1CCCC2(C)CC12
O=C1C=CCC2OC12
124.139
32.042
0.6729
2
0
39,349
2.68924
1.82275
1.33158
2.4884
77.94
-0.2354
0.0755
0.3109
1,010.7336
0.17447
-403.14093
-403.133683
-403.132739
-403.172608
29.364
C1CC2OCC3NC23C1
C1CC2OCC3NC32C1
false
C1CC2CCC3CC23C1
C1CC2OCC3NC32C1
125.171
33.2457
0.2797
2
1
132,329
1.98667
1.48429
0.84956
2.2142
55.43
-0.2783
-0.0784
0.1999
1,154.8502
0.051256
-557.882306
-557.874508
-557.873563
-557.91583
26.304
FC1=CC(F)=NC(=O)O1
O=c1nc(F)cc(F)o1
false
CC1CC(C)CC(C)C1
O=c1nccco1
133.053
22.689
0.313
3
0
83,150
2.17231
1.85055
1.46794
2.5582
60.91
-0.251
-0.0016
0.2494
940.1333
0.112276
-494.915657
-494.907763
-494.906819
-494.94785
29.815
OC1C2COC(=O)C12O
O=C1OCC2C(O)C12O
false
CC1CCC2C(C)C12C
O=C1OCC2CC12
130.099
25.4056
-1.735
4
2
47,705
2.40151
1.63598
1.15026
3.0331
68.51
-0.2552
-0.0365
0.2188
1,064.7372
0.136228
-459.012881
-459.004804
-459.003859
-459.046045
29.964
O=C1CCCOC(=O)C1
O=C1CCCOC(=O)C1
true
CC1CCCCC(C)C1
O=C1CCCOC(=O)C1
128.127
29.817
0.2826
3
0
97,693
2.91854
0.79906
0.69498
4.4098
87.83
-0.2495
0.0156
0.2651
1,684.7948
0.146247
-364.792888
-364.783117
-364.782173
-364.828945
34.585
CCC#CC1(CC1)C#N
CCC#CC1(C#N)CC1
false
CCCCC1(CC)CC1
C1CC1
119.167
35.347
1.70358
1
0
96,472
2.29018
1.85108
1.32484
0.9324
74.82
-0.2224
0.0815
0.3039
1,025.0814
0.173254
-440.248704
-440.240966
-440.240021
-440.280441
31.41
OC1COCCN2CC12
OC1COCCN2CC12
true
CC1CCCCC2CC12
C1CC2CN2CCO1
129.159
32.1868
-0.9383
3
1
44,163
3.86129
1.01382
0.99436
1.9997
75.12
-0.2485
-0.0314
0.2171
1,221.4925
0.12279
-400.677058
-400.6689
-400.667956
-400.710484
30.654
O=C1CN2C(CC#C)C12
C#CCC1C2C(=O)CN12
false
CCCC1C2CC(C)C12
O=C1CN2CC12
121.139
32.739
-0.3548
2
0
31,074
2.40801
1.3397
0.87496
1.507
82.01
-0.1842
0.0277
0.2119
1,345.8869
0.157267
-423.058243
-423.0484
-423.047456
-423.093535
34.655
COC1=C(C)OC(C)=C1
COc1cc(C)oc1C
false
CCC1CC(C)CC1C
c1ccoc1
126.155
34.734
1.90504
2
0
104,494
2.29753
1.70189
1.18353
1.5492
69.73
-0.237
-0.0318
0.2052
1,060.9492
0.133544
-458.906772
-458.898194
-458.89725
-458.940064
31.139
COC1(C=O)C2COC12
COC1(C=O)C2COC21
false
CCC1(CC)C2CCC21
C1OC2CC12
128.127
29.034
-0.4009
3
0
91,669
3.20172
1.2296
1.09425
0.8651
88.89
-0.2475
0.0546
0.3021
1,206.9144
0.183612
-349.917471
-349.909222
-349.908277
-349.949801
33.469
CC1CC2CC1C2C#C
C#CC1C2CC(C)C1C2
false
CCC1C2CC(C)C1C2
C1CC2CC1C2
120.195
37.701
1.9117
0
0
127,558
4.56666
1.10024
0.93352
1.4562
77.32
-0.2165
0.0046
0.2211
1,253.4536
0.137675
-414.161046
-414.152823
-414.151878
-414.195369
29.147
CN1N=CC(=N1)N1CC1
Cn1ncc(N2CC2)n1
false
CC1CCC(C2CC2)C1
c1n[nH]nc1N1CC1
124.147
33.216
-0.3649
4
0
80,157
2.45792
1.60938
1.36712
4.5145
74.93
-0.2347
-0.0582
0.1765
1,015.1317
0.1375
-418.028716
-418.020799
-418.019855
-418.061075
30.455
CC1C2NC(=N)C(=O)C12
CC1C2NC(=N)C(=O)C12
true
CC1CC2C(C)C2C1C
N=C1NC2CC2C1=O
124.143
32.3114
-0.22953
2
2
8,998
6.35056
0.97243
0.88647
4.638
61.66
-0.2455
-0.0818
0.1637
1,214.2123
0.104689
-415.869328
-415.860662
-415.859718
-415.903652
29.002
N=C(NCC=O)C=O
N=C(C=O)NCC=O
false
CCCCC(C)CC
114.104
27.8574
-1.04893
3
2
23,655
4.06891
1.95087
1.32943
1.7946
57.07
-0.2838
-0.0597
0.2241
837.1656
0.084638
-418.874186
-418.867593
-418.866649
-418.906518
22.857
CC1=NC=NC(F)=N1
Cc1ncnc(F)n1
false
CC1CCCC(C)C1
c1ncncn1
113.095
24.522
0.31912
3
0
4,255
3.98213
2.10754
1.37815
5.1549
56.12
-0.2746
-0.066
0.2086
798.0616
0.072733
-434.584033
-434.577783
-434.576839
-434.615035
22.617
N=C1OC=CC(=O)O1
N=c1occc(=O)o1
false
CC1CCCC(C)C1
N=c1occc(=O)o1
113.072
23.0987
-0.28773
4
1
126,355
2.99772
1.34268
0.94084
2.497
72.74
-0.2693
-0.1099
0.1594
1,197.2353
0.110599
-450.084099
-450.075666
-450.074722
-450.118329
29.973
CCC1=NC(=N)ON=N1
CCc1nnoc(=N)n1
false
CCC1CCCC(C)C1
N=c1ncnno1
126.119
27.3257
-0.49353
5
1
96,164
2.47191
1.38251
0.97293
1.529
85.02
-0.2581
0.0775
0.3355
1,270.8707
0.208497
-388.29508
-388.28662
-388.285676
-388.327596
34.54
OC1CCCC2CC2C1
OC1CCCC2CC2C1
true
CC1CCCC2CC2C1
C1CCC2CC2CC1
126.199
36.0718
1.5574
1
1
62,185
5.23995
0.62597
0.57717
3.8965
79.98
-0.2734
0.0049
0.2783
1,841.1984
0.144377
-401.914465
-401.90414
-401.903196
-401.950902
35.722
CC(COCC#N)C#C
C#CC(C)COCC#N
false
CCCCCC(C)CC
123.155
34.429
0.79588
2
0
45,899
2.24004
1.98073
1.21132
3.2568
71.36
-0.249
-0.0431
0.2059
997.0082
0.126316
-434.051148
-434.043609
-434.042664
-434.083382
28.495
O=C1CN=CNC=NC1
O=C1CN=CNC=NC1
true
CC1CCCCCCC1
O=C1CN=CNC=NC1
125.131
34.8607
-0.7847
4
1
101,164
2.29237
1.06709
0.87302
1.1955
89.05
-0.2431
0.0587
0.3018
1,496.8475
0.226677
-389.483252
-389.471967
-389.471023
-389.519681
41.504
CCC(C)C1C(C)C1O
CCC(C)C1C(C)C1O
true
CCC(C)C1C(C)C1C
C1CC1
128.215
38.1158
1.6593
1
1
5,080
3.36684
1.93561
1.24666
0.6467
67.9
-0.1784
0.0582
0.2366
947.4946
0.130515
-379.950545
-379.941701
-379.940757
-379.983819
31.552
CC1=CNC(N)=C1O
Cc1c[nH]c(N)c1O
false
CC1CCC(C)C1C
c1cc[nH]c1
112.132
31.6069
0.61092
2
3
92,742
2.47304
1.53536
1.13306
3.1982
71.4
-0.2334
-0.0071
0.2264
1,092.018
0.139226
-451.3761
-451.367766
-451.366822
-451.408852
31.984
NC1CN=C(N)NC1=O
NC1=NCC(N)C(=O)N1
false
CC1CCC(C)C(C)C1
O=C1CCN=CN1
128.135
32.6075
-2.2418
4
3
8,419
3.40021
1.77584
1.49464
1.6442
78.12
-0.2218
0.0751
0.2969
964.1598
0.188186
-329.086508
-329.078027
-329.077083
-329.118567
33.144
CC1C2N1CC2(C)C
CC1C2N1CC2(C)C
true
CC1C2CC(C)(C)C12
C1CN2CC12
111.188
33.737
1.0989
1
0
106,392
3.24609
1.44482
1.25312
0.7481
78.22
-0.2285
0.0754
0.3039
1,063.1067
0.172787
-403.085305
-403.077673
-403.076729
-403.117221
31.118
OCC12CC(C1)C1CN21
OCC12CC(C1)C1CN12
false
CCC12CC(C1)C1CC12
C1C2CC1N1CC21
125.171
33.0348
-0.1747
2
1
91,639
2.81982
1.72034
1.50244
1.9345
76.51
-0.2242
0.0772
0.3014
962.7784
0.175126
-403.131801
-403.124824
-403.12388
-403.162733
29.734
OC1CC2CC1C1NC21
OC1CC2CC1C1NC21
true
CC1CC2CC1C1CC21
C1CC2CC1C1NC21
125.171
32.9325
-0.2725
2
2
24,666
4.4473
1.13962
0.9652
3.1951
78.56
-0.2514
-0.0267
0.2247
1,187.404
0.12685
-400.781178
-400.774085
-400.773141
-400.813311
26.857
C1OC1C1=CN=CC=C1
c1cncc(C2CO2)c1
false
C1CCC(C2CC2)CC1
c1cncc(C2CO2)c1
121.139
32.93
1.1529
2
0
45,832
2.65185
1.62369
1.10579
3.1925
82.37
-0.2243
-0.0575
0.1668
1,071.151
0.126502
-400.783963
-400.776385
-400.775441
-400.816219
28.965
O=C1NC=CC=CC=C1
O=C1C=CC=CC=CN1
false
CC1CCCCCCC1
O=C1C=CC=CC=CN1
121.139
35.5627
0.7423
1
1
28,848
3.1066
1.57003
1.2346
6.6834
68.75
-0.2476
-0.082
0.1656
969.7979
0.091011
-448.963936
-448.956611
-448.955666
-448.995702
27.294
NC1=NC=NC(=O)N=C1
Nc1cnc(=O)ncn1
false
CC1CCCC(C)CC1
O=c1nccncn1
124.103
30.5094
-1.186
5
1
29,811
2.52548
1.31347
0.87351
4.667
86.61
-0.2194
-0.0402
0.1791
1,313.137
0.147246
-402.006743
-401.997504
-401.996559
-402.041343
32.646
CN1C=C(C)C=C1C=O
Cc1cc(C=O)n(C)c1
false
CCC1CC(C)CC1C
c1cc[nH]c1
123.155
35.5375
1.14602
2
0
91,581
2.79276
1.1718
0.97039
2.734
79.9
-0.2303
-0.0268
0.2035
1,272.447
0.169599
-403.116643
-403.107495
-403.106551
-403.151336
33.771
CC1CC2NC12CC=O
CC1CC2NC12CC=O
true
CCCC12CC1CC2C
C1CC2NC12
125.171
34.1167
0.3258
2
1
133,736
2.12328
1.33751
0.98693
3.5937
58.34
-0.3374
0.015
0.3524
1,187.5967
0.107917
-548.339001
-548.329827
-548.328883
-548.373765
31.995
CCC(C#N)C(F)(F)F
CCC(C#N)C(F)(F)F
true
CCC(CC)C(C)(C)C
137.104
25.449
2.09848
1
0
10,159
2.54994
1.29502
0.90234
2.4939
62.9
-0.2797
-0.0535
0.2261
1,208.0351
0.116433
-399.810058
-399.800915
-399.79997
-399.84512
30.252
OCCC(C=O)C#N
N#CC(C=O)CCO
false
CCCC(CC)CC
113.116
26.8698
-0.29252
3
1
82,997
3.77813
1.60729
1.49148
2.0043
65.7
-0.2524
0.0788
0.3312
905.2936
0.139211
-458.944026
-458.937758
-458.936814
-458.974416
26.371
OC1C2OC3OCC2C13
OC1C2OC3OCC2C31
false
CC1C2CC3CCC2C31
C1OC2OC3CC2C13
128.127
27.5998
-0.6516
3
1
116,590
3.9526
0.93572
0.79225
3.2041
73.42
-0.2639
0.0009
0.2648
1,435.8637
0.136143
-455.209122
-455.200146
-455.199202
-455.244428
31.334
CCN=C1CNC(=O)O1
CCN=C1CNC(=O)O1
true
CCCC1CCC(C)C1
N=C1CNC(=O)O1
128.131
32.4597
0.1446
3
1
77,233
3.24832
1.05853
0.89496
2.1557
73.29
-0.2405
-0.0409
0.1996
1,294.1866
0.145338
-439.079107
-439.06977
-439.068826
-439.114283
32.715
CC1C(NC1C=O)C=O
CC1C(C=O)NC1C=O
false
CCC1CC(CC)C1C
C1CNC1
127.143
32.0037
-0.6393
3
1
808
3.31007
1.92301
1.3919
0.6108
67.1
-0.2392
0.0153
0.2545
933.3907
0.158157
-326.949535
-326.940745
-326.939801
-326.982785
31.175
CCC(CC)=NO
CCC(CC)=NO
true
CCC(CC)CC
101.149
29.8035
1.6366
2
1
23,445
3.57488
1.16829
1.04347
1.5603
75.59
-0.2426
0.0022
0.2447
1,176.635
0.148508
-439.035545
-439.027681
-439.026737
-439.068382
30.16
ON=C1CC2COCC12
ON=C1CC2COCC12
true
CCC1CC2CCCC12
N=C1CC2COCC12
127.143
31.6375
0.4829
3
1
108,949
3.50511
1.04088
1.02091
1.7787
84.39
-0.2187
0.0146
0.2333
1,305.4964
0.18297
-387.091
-387.082181
-387.081237
-387.124526
34.19
CCC1=CC2C(O)C2C1
CCC1=CC2C(O)C2C1
true
CCC1CC2C(C)C2C1
C1=CC2CC2C1
124.183
35.9778
1.3334
1
1
113,694
2.78853
0.93076
0.85188
1.8474
65.93
-0.2745
-0.0464
0.2281
1,392.892
0.132917
-496.075229
-496.065674
-496.06473
-496.110735
33.598
OCC1OC1C(=O)CO
O=C(CO)C1OC1CO
false
CCC(C)C1CC1CC
C1CO1
132.115
27.8396
-1.6925
4
2
90,478
2.33668
1.82359
1.39799
2.9556
72.43
-0.2356
-0.0506
0.185
980.0134
0.148837
-439.06986
-439.062138
-439.061194
-439.101889
30.194
OC1CC2C(C=O)N2C1
O=CC1C2CC(O)CN12
false
CCC1C2CC(C)CC12
C1CC2CN2C1
127.143
30.9698
-0.9973
3
1
34,266
4.17825
1.34568
1.22715
5.0958
73.44
-0.2502
-0.0023
0.2479
1,018.6884
0.126272
-400.730032
-400.723205
-400.722261
-400.761247
27.04
N#CC12OC3CCC1C23
N#CC12OC3CCC1C32
false
CCC12CC3CCC1C32
C1CC2C3OC1C23
121.139
29.431
0.68738
2
0
132,490
3.05704
1.29838
0.91646
1.8919
75.76
-0.2127
-0.005
0.2076
1,195.4513
0.123818
-445.92758
-445.919468
-445.918523
-445.960313
30.842
CC1=CC(O)=CC=C1F
Cc1cc(O)ccc1F
false
CC1CCC(C)C(C)C1
c1ccccc1
126.13
32.8018
1.83972
1
1
91,390
2.26995
1.74985
1.4708
3.2174
76.65
-0.2372
0.0576
0.2948
1,016.5937
0.185123
-424.231475
-424.223654
-424.222709
-424.263259
32.441
OC1CC2CC(O)CC12
OC1CC2CC(O)C2C1
false
CC1CC2CC(C)C2C1
C1CC2CCC2C1
128.171
32.8446
0.1381
2
2
117,514
2.3329
1.04306
0.80349
2.7779
77.6
-0.2469
-0.0426
0.2043
1,487.8421
0.156563
-419.230785
-419.220137
-419.219193
-419.267452
36.505
CCNC(C#N)C(C)=O
CCNC(C#N)C(C)=O
true
CCCC(CC)C(C)C
126.159
33.7587
0.07708
3
1
118,754
3.27782
0.80387
0.74703
1.3081
89.73
-0.2506
0.0722
0.3228
1,706.5539
0.22697
-389.495241
-389.484488
-389.483544
-389.53109
40.516
CCCC1(O)CC(C)C1
CCCC1(O)CC(C)C1
true
CCCC1(C)CC(C)C1
C1CCC1
128.215
38.2558
1.9475
1
1
122,530
4.79527
0.57048
0.54342
2.1223
84.71
-0.2485
0.0766
0.325
2,105.632
0.203612
-425.396884
-425.385921
-425.384977
-425.434272
38.49
CCOCC1CC1CO
CCOCC1CC1CO
true
CCCCC1CC1CC
C1CC1
130.187
35.1758
0.6513
2
1
50,469
4.39677
0.94577
0.81885
2.5024
69.96
-0.268
-0.045
0.223
1,334.31
0.135867
-459.012496
-459.004046
-459.003102
-459.046769
30.088
O=CC1CCC(=O)OC1
O=CC1CCC(=O)OC1
true
CCC1CCC(C)CC1
O=C1CCCCO1
128.127
29.747
0.1385
3
0
90,821
3.36295
1.77832
1.59466
1.5233
76.46
-0.2319
0.0927
0.3246
914.4277
0.161615
-385.848236
-385.841584
-385.84064
-385.878988
28.029
CC1OC2C3C4C3C1C24
CC1OC2C3C1C1C2C31
false
CC1CC2C3C1C1C2C31
C1OC2C3C1C1C2C31
122.167
31.785
0.8955
1
0
115,568
2.28893
1.12337
1.06835
2.8652
79.17
-0.2492
-0.029
0.2202
1,309.878
0.179534
-424.22886
-424.218605
-424.217661
-424.264647
36.941
CCC1CCC1(O)C=O
CCC1CCC1(O)C=O
true
CCC1CCC1(C)CC
C1CCC1
128.171
34.0288
0.7364
2
1
75,948
2.22384
1.88529
1.07006
2.5029
75.14
-0.2278
-0.0008
0.227
1,105.1318
0.149888
-435.327072
-435.318583
-435.317639
-435.360043
32.107
CN1C(=O)CCN=C1N
CN1C(=O)CCN=C1N
true
CC1CCCC(C)C1C
O=C1CCN=CN1
127.147
33.8764
-0.8368
3
1
104,570
3.12606
1.16957
1.00733
0.9698
67.43
-0.2665
-0.0609
0.2056
1,178.9018
0.122485
-475.023038
-475.014392
-475.013447
-475.056774
31.451
OCC1(CC(=N)O1)C=O
N=C1CC(C=O)(CO)O1
false
CCC1(CC)CC(C)C1
N=C1CCO1
129.115
29.3095
-0.68603
4
2
39,379
2.38938
1.69393
1.10001
2.2028
80.68
-0.2268
0.038
0.2648
1,123.8262
0.173619
-403.132466
-403.124618
-403.123674
-403.164747
30.994
C1C2CCN=COCC12
C1=NCCC2CC2CO1
false
C1CCCC2CC2CC1
C1=NCCC2CC2CO1
125.171
35.525
1.0711
2
0
39,006
3.11587
1.76032
1.29494
0.1671
87.45
-0.2063
0.0214
0.2276
1,007.3544
0.162009
-348.761295
-348.754459
-348.753515
-348.792052
28.953
C1C2CC=C3CC=CC123
C1=CC23CC2CC=C3C1
false
C1CC2CCC3CC23C1
C1=CC23CC2CC=C3C1
118.179
36.997
2.2827
0
0
105,175
2.09629
1.02315
0.79181
0.2412
96.85
-0.222
0.063
0.2851
1,607.1361
0.202995
-351.133037
-351.121742
-351.120798
-351.170506
40.151
CCC1(CC1C)C#CC
CC#CC1(CC)CC1C
false
CCCC1(CC)CC1C
C1CC1
122.211
39.955
2.4459
0
0
6,872
2.91004
1.68382
1.47596
3.747
66.26
-0.2557
0.0259
0.2816
922.6749
0.129295
-379.915369
-379.906631
-379.905687
-379.948115
31.937
CC1(N)C(O)C1C#N
CC1(N)C(O)C1C#N
true
CCC1C(C)C1(C)C
C1CC1
112.132
27.7022
-0.78192
3
2
18,093
3.74651
2.20495
1.6527
0.1447
76.91
-0.2352
0.0284
0.2636
823.9441
0.157143
-310.696154
-310.689815
-310.688871
-310.726622
25.679
C1C=CC2CC=CC12
C1=CC2CC=CC2C1
false
C1CC2CCCC2C1
C1=CC2CC=CC2C1
106.168
34.494
2.1386
0
0
55,438
3.11103
0.81558
0.72658
0.8155
70.62
-0.1766
0.0447
0.2214
1,550.8523
0.135534
-455.209924
-455.199926
-455.198982
-455.248215
33.299
[O-]C(=O)C1CCNC1=[NH2+]
[NH2+]=C1NCCC1C(=O)[O-]
false
CC(C)C1CCCC1C
[NH2+]=C1CCCN1
128.131
28.0491
-3.4966
2
2
109,068
4.01938
1.3192
1.18965
3.477
71.82
-0.2534
-0.0083
0.245
1,057.4099
0.137554
-417.96212
-417.954913
-417.953968
-417.993869
28.204
OCC1=NC2CC3C2N13
OCC1=NC2CC3C2N13
true
CCC1CC2CC3C1C23
C1=NC2CC3C2N13
124.143
32.3408
-0.7841
3
1
36,456
3.60663
1.00675
0.86885
5.6367
76.83
-0.2613
0.0319
0.2933
1,332.9611
0.147215
-401.926555
-401.917941
-401.916997
-401.960622
31.483
N#CCC1OCC11CC1
N#CCC1OCC12CC2
false
CCCC1CCC12CC2
C1CC12COC2
123.155
31.637
1.07908
2
0