index
int64
1
134k
A
float64
0
620k
B
float64
0.34
438
C
float64
0.33
283
mu
float64
0
29.6
alpha
float64
6.31
197
homo
float64
-0.43
-0.1
lumo
float64
-0.18
0.19
gap
float64
0.02
0.62
r2
float64
19
3.37k
zpve
float64
0.02
0.27
U0
float64
-714.57
-40.48
U
float64
-714.56
-40.48
H
float64
-714.56
-40.48
G
float64
-714.6
-40.5
Cv
float64
6
47
smiles
stringlengths
1
28
canonsmiles
stringlengths
1
34
isSmilesEqual
bool
2 classes
generic_scaffold
stringlengths
1
21
scaffold
stringlengths
0
31
rdkit_WT
float64
16
152
rdkit_MR
float64
3.61
43.7
rdkit_LogP
float64
-4.91
3.76
rdkit_HA
float64
0
7
rdkit_HD
float64
0
5
62,138
4.7793
0.67304
0.64676
4.0368
77.61
-0.2636
0.0147
0.2783
1,697.7797
0.15833
-419.255457
-419.245245
-419.244301
-419.29212
35.318
CC(CNC=O)CC#N
CC(CC#N)CNC=O
false
CCCCC(C)CCC
126.159
33.4607
0.28218
2
1
56,229
5.12438
0.62881
0.56612
4.9082
69.72
-0.2508
-0.0163
0.2344
1,889.663
0.144537
-476.290721
-476.280105
-476.279161
-476.329015
35.801
CC(=O)CCOC(N)=O
CC(=O)CCOC(N)=O
true
CC(C)CCCC(C)C
131.131
30.8334
0.0608
3
1
11,972
2.87066
1.97166
1.75119
2.4142
67.89
-0.2267
0.0665
0.2931
868.0129
0.151644
-384.904857
-384.896617
-384.895673
-384.93706
31.46
CC1(O)COC11CC1
CC1(O)COC12CC2
false
CC1(C)CCC12CC2
C1CC2(CC2)O1
114.144
28.5408
0.3002
2
1
102,036
2.14756
1.40146
0.91312
1.6273
71.28
-0.2642
-0.0166
0.2476
1,296.2932
0.145622
-476.282744
-476.272645
-476.271701
-476.318691
34.3
CCN(C=O)C(=O)OC
CCN(C=O)C(=O)OC
true
CCC(C)C(CC)CC
131.131
30.849
0.2311
3
0
123,832
3.58369
1.56087
1.12915
3.3024
67.02
-0.2604
-0.0393
0.221
1,005.8032
0.114502
-453.926601
-453.919845
-453.918901
-453.957807
26.034
C1CC2=C(CO1)ON=N2
C1Cc2nnoc2CO1
false
C1CCC2CCCC2C1
C1Cc2nnoc2CO1
126.115
27.658
0.1423
4
0
39,848
2.88841
1.76594
1.37701
1.5129
71.4
-0.229
0.0526
0.2816
952.7243
0.137794
-417.922502
-417.915696
-417.914752
-417.953536
27.899
C1OC11C2NC2C2NC12
C1OC12C1NC1C1NC12
false
C1C2C3CC3C3(CC3)C12
C1OC12C1NC1C1NC12
124.143
30.1064
-1.5502
3
2
21,034
3.91161
1.81928
1.26134
1.8818
63.71
-0.23
0.0336
0.2636
938.5634
0.119609
-396.023521
-396.015516
-396.014571
-396.056208
28.052
CN1N=C(C)N=C1O
Cc1nc(O)n(C)n1
false
CC1CC(C)C(C)C1
c1nc[nH]n1
113.12
27.4048
-0.17088
4
1
131,741
2.0398
1.80698
1.00772
5.1999
66.19
-0.2828
-0.0507
0.2321
1,088.292
0.091294
-448.933062
-448.925205
-448.924261
-448.966893
27.404
OCC1=NNN=C1C#N
N#Cc1n[nH]nc1CO
false
CCC1CCCC1CC
c1cn[nH]n1
124.103
27.0205
-0.83132
4
2
28,212
4.54397
1.22203
0.98833
1.4316
79.77
-0.2133
0.0134
0.2267
1,207.3562
0.149929
-402.000702
-401.992834
-401.99189
-402.033457
29.265
CC1=NC2=C(CCC2)O1
Cc1nc2c(o1)CCC2
false
CC1CC2CCCC2C1
c1nc2c(o1)CCC2
123.155
33.265
1.47172
2
0
110,996
2.82427
1.48348
1.22769
3.0237
75.11
-0.2316
0.0062
0.2378
1,066.8459
0.159689
-422.981223
-422.973139
-422.972194
-423.013456
32.579
OCC1C2CC1(O)C=C2
OCC1C2C=CC1(O)C2
false
CCC1C2CCC1(C)C2
C1=CC2CC1C2
126.155
32.7726
-0.0843
2
2
133,552
3.01706
1.33289
1.32606
2.9179
54.46
-0.2575
0.0676
0.325
979.6806
0.097007
-568.120229
-568.112866
-568.111922
-568.152935
27.539
FC(F)(F)C12CC(C1)O2
FC(F)(F)C12CC(C1)O2
true
CC(C)(C)C12CC(C1)C2
C1C2CC1O2
138.088
22.893
1.4801
1
0
40,201
3.07775
1.5917
1.27338
1.2114
71.18
-0.2442
0.0612
0.3054
1,012.1944
0.149581
-439.034358
-439.027071
-439.026127
-439.066279
28.422
C1NC11COC2COC12
C1OC2C1OCC21CN1
false
C1CC2C1CCC21CC1
C1OC2C1OCC21CN1
127.143
30.2137
-0.874
3
1
57,149
3.41593
0.70167
0.60907
4.0363
88.35
-0.2617
-0.0566
0.2051
1,811.5027
0.156811
-385.858591
-385.848467
-385.847523
-385.896346
34.974
CC(C#CC=O)C1CC1
CC(C#CC=O)C1CC1
true
CCCCC(C)C1CC1
C1CC1
122.167
35.728
1.2348
1
0
128,148
2.23447
1.5386
0.92047
2.1362
84.34
-0.1903
-0.0108
0.1795
1,223.6664
0.124998
-396.909957
-396.901188
-396.900244
-396.94354
32.226
CNC1=C(NN=C1)C#C
C#Cc1[nH]ncc1NC
false
CCC1CCCC1CC
c1cn[nH]c1
121.143
36.0694
0.4327
2
2
9,357
7.71213
0.80881
0.7457
2.4503
66.62
-0.2608
0.0171
0.2779
1,534.9037
0.150662
-422.09839
-422.088514
-422.08757
-422.134558
32.438
CCOCC(=O)OC
CCOCC(=O)OC
true
CCCCC(C)CC
118.132
28.509
0.1959
3
0
79,462
2.46022
1.87596
1.46978
1.4787
77.41
-0.2263
0.0649
0.2913
982.8176
0.172636
-403.091414
-403.08374
-403.082796
-403.123022
31.317
CC12CN3CC1C3C2O
CC12CN3CC1C3C2O
true
CC1C2C3CC2C1(C)C3
C1C2CN3CC2C13
125.171
32.9648
-0.3188
2
1
45,372
2.99914
1.63145
1.42391
4.8269
66.65
-0.2609
0.0089
0.2697
950.2923
0.138933
-459.018865
-459.012048
-459.011104
-459.050359
26.953
O=C1CC2COC(C2)O1
O=C1CC2COC(C2)O1
true
CC1CC2CCC(C1)C2
O=C1CC2COC(C2)O1
128.127
28.556
0.2959
3
0
3,863
8.00909
2.08678
1.65781
2.8238
49.28
-0.2172
0.0235
0.2407
680.8995
0.079578
-376.570473
-376.564499
-376.563555
-376.599912
22.588
NC1=CC(O)=NO1
Nc1cc(O)no1
false
CC1CCC(C)C1
c1cnoc1
100.077
22.5802
-0.0376
4
2
24,515
3.98309
1.70602
1.19443
1.2945
75.96
-0.2405
-0.0275
0.213
947.3893
0.105723
-399.644019
-399.638263
-399.637319
-399.674024
23.532
O1C=NC2=C1C=CC=C2
c1ccc2ocnc2c1
false
C1CCC2CCCC2C1
c1ccc2ocnc2c1
119.123
34.009
1.8278
2
0
62,763
3.75829
1.25578
1.21596
5.0577
68.04
-0.2765
0.0384
0.3149
1,080.5134
0.135228
-458.999421
-458.99127
-458.990326
-459.032043
30.583
CC1(C)C2OC(=O)OC12
CC1(C)C2OC(=O)OC21
false
CC1CC2C(C1)C2(C)C
O=C1OC2CC2O1
128.127
28.923
0.9302
3
0
124,938
2.29123
1.84424
1.03478
5.596
74.96
-0.258
-0.0768
0.1812
1,107.15
0.122685
-437.908429
-437.899637
-437.898693
-437.943827
30.887
CC1=C(C)C(=O)ON=C1
Cc1cnoc(=O)c1C
false
CC1CCCC(C)C1C
O=c1cccno1
125.127
32.247
0.65164
3
0
37,360
2.45182
1.93875
1.88974
1.4028
76.7
-0.2236
0.0826
0.3062
897.3662
0.175524
-403.119172
-403.112575
-403.111631
-403.149674
28.198
C1C2C3CC(COC3)N12
C1OCC2CC1C1CN21
false
C1CC2CC(C1)C1CC21
C1OCC2CC1C1CN21
125.171
33.208
0.0893
2
0
16,338
2.96569
1.84644
1.4136
1.7763
71.34
-0.2302
0.0618
0.2919
961.3849
0.165097
-365.018378
-365.010047
-365.009103
-365.051085
31.233
CCC12CN1CC2O
CCC12CN1CC2O
true
CCC12CC1CC2C
C1CN2CC12
113.16
30.6018
-0.1747
2
1
110,974
2.33147
1.24251
1.06192
1.8234
86.57
-0.2295
0.0911
0.3205
1,323.231
0.203684
-388.240221
-388.230329
-388.229385
-388.274647
37.505
CCC1C2OC1(C)C2C
CCC1C2OC1(C)C2C
true
CCC1C2CC1(C)C2C
C1C2CC1O2
126.199
36.223
1.8198
1
0
125,379
2.94745
1.26623
0.97975
4.8344
74.58
-0.2466
0.0087
0.2553
1,182.5819
0.125761
-396.974697
-396.966211
-396.965267
-397.008603
30.36
CC1=CNN=C1CC#N
Cc1c[nH]nc1CC#N
false
CCCC1CCCC1C
c1cn[nH]c1
121.143
32.6417
0.7842
2
1
62,571
2.40819
1.47512
1.17503
2.8011
77.48
-0.2349
-0.0071
0.2278
1,124.0282
0.156503
-423.023119
-423.013939
-423.012995
-423.056325
35.371
CC1(O)C2C(=O)CC12C
CC1(O)C2C(=O)CC21C
false
CC1CC2(C)C1C2(C)C
O=C1CC2CC12
126.155
31.8448
0.3463
2
1
43,757
3.33596
1.28056
1.08503
2.9802
78.63
-0.2513
0.0208
0.272
1,153.2146
0.147842
-401.908463
-401.900625
-401.899681
-401.941187
30.559
N=C1OC2(CC12)C1CC1
N=C1OC2(C3CC3)CC12
false
CC1CC2(C3CC3)CC12
N=C1OC2(C3CC3)CC12
123.155
32.3737
1.16257
2
1
28,758
3.95229
1.05792
0.96212
2.6157
66.07
-0.2241
0.0164
0.2405
1,205.2618
0.102224
-470.032538
-470.02461
-470.023665
-470.06597
28.64
OC1=NC=C(NC=N)O1
N=CNc1cnc(O)o1
false
CCCC1CCC(C)C1
c1cocn1
127.103
30.5742
0.39917
4
3
37,257
3.17932
2.16865
1.73542
1.3131
76.32
-0.2133
0.0677
0.281
834.9344
0.150869
-364.722162
-364.716282
-364.715338
-364.75189
26.324
C1C2C3C4C3C3C4N3C12
C1C2C3C4C3C3C4N3C12
true
C1C2C1C1C3C4C2C4C13
C1C2C3C4C3C3C4N3C12
119.167
31.78
0.3171
1
0
44,299
3.89519
1.78441
1.56825
4.5978
66.94
-0.239
0.0068
0.2458
838.2793
0.116113
-416.7737
-416.767918
-416.766973
-416.803676
24.318
O=C1NC2C3C4C2C1N34
O=C1NC2C3C1N1C2C31
false
CC1CC2C3C1C1C2C31
O=C1NC2C3C1N1C2C31
122.127
28.6237
-1.4504
2
1
119,823
4.19314
0.80265
0.70791
3.2563
75.37
-0.2125
0.0014
0.214
1,558.0373
0.147292
-439.130563
-439.12142
-439.120476
-439.165278
33.11
OCCC1=CCC(=O)N1
O=C1CC=C(CCO)N1
false
CCCC1CCC(C)C1
O=C1CC=CN1
127.143
32.5455
-0.2274
2
2
62,849
2.66891
1.53597
1.35014
3.1181
82.06
-0.2298
-0.0032
0.2266
1,068.0999
0.183054
-387.104669
-387.096364
-387.09542
-387.136934
33.549
CC1(C)C2CC1C(=O)C2
CC1(C)C2CC(=O)C1C2
false
CC1CC2CC1C2(C)C
O=C1CC2CC1C2
124.183
35.002
1.6215
1
0
91,284
3.00712
1.37948
1.12969
2.7736
71.38
-0.2471
0.0259
0.273
1,096.1098
0.149857
-439.122543
-439.114854
-439.11391
-439.154959
30.232
OC1CC2CC(=O)NC12
O=C1CC2CC(O)C2N1
false
CC1CC2CC(C)C2C1
O=C1CC2CCC2N1
127.143
30.6615
-0.7443
2
2
14,689
9.87057
0.59889
0.57374
0.884
83.09
-0.2462
0.0411
0.2873
1,929.4683
0.150838
-310.613091
-310.603193
-310.602248
-310.650228
34.043
CCCC#CCC#C
C#CCC#CCCC
false
CCCCCCCC
106.168
36.134
1.8132
0
0
61,145
3.20713
1.01395
0.89067
2.8846
79.05
-0.2466
-0.0452
0.2014
1,307.5668
0.122409
-396.897834
-396.887989
-396.887044
-396.933802
34.082
CN(CC#C)C(=N)C#N
C#CCN(C)C(=N)C#N
false
CCCC(C)C(C)CC
121.143
34.8027
0.05225
2
1
46,192
3.09886
1.61599
1.21787
2.1891
73.28
-0.2282
-0.0377
0.1905
1,012.4383
0.137271
-417.920109
-417.912828
-417.911883
-417.952039
28.467
O=C1CNC11C2CC1N2
O=C1CNC12C1CC2N1
false
CC1CCC12C1CC2C1
O=C1CNC12C1CC2N1
124.143
31.0694
-1.3584
3
2
101,441
2.78765
0.98526
0.82449
1.4067
88.96
-0.2541
0.0684
0.3226
1,538.5593
0.227858
-389.489214
-389.478566
-389.477622
-389.524792
39.912
CCC(O)C1CCC1C
CCC(O)C1CCC1C
true
CCC(C)C1CCC1C
C1CCC1
128.215
38.1858
1.8034
1
1
55,648
3.05435
1.02758
0.93104
3.208
76.92
-0.2534
-0.0278
0.2256
1,349.5062
0.166259
-440.312053
-440.301225
-440.300281
-440.348657
38.2
CC(=N)OC(C)(C)C=O
CC(=N)OC(C)(C)C=O
true
CCC(C)(C)CC(C)C
129.159
34.6287
0.97767
3
1
29,012
2.6353
1.55969
0.98064
3.4646
79.19
-0.2293
-0.0747
0.1546
1,120.4952
0.114465
-416.874831
-416.867139
-416.866195
-416.907064
28.946
NC1=CN=CC=C1C=O
Nc1cnccc1C=O
false
CCC1CCCCC1C
c1ccncc1
122.127
34.0369
0.4763
3
1
71,290
2.57085
1.87711
1.42266
1.434
81.41
-0.2324
0.091
0.3234
1,004.3386
0.184804
-387.069607
-387.062094
-387.06115
-387.100904
31.286
CC12CC3C(COC1)C23
CC12COCC3C(C1)C32
false
CC12CCCC3C(C1)C32
C1OCC2C3CC1C23
124.183
34.013
1.2888
1
0
8,229
5.42872
1.03755
1.00615
3.5171
69.96
-0.2391
0.0594
0.2985
1,216.7394
0.155133
-381.154633
-381.146298
-381.145353
-381.188258
30.81
NC(=O)NC1CCC1
NC(=O)NC1CCC1
true
CC(C)CC1CCC1
C1CCC1
114.148
30.3581
0.2072
1
2
57,101
3.09169
1.18826
0.90979
4.9049
72.6
-0.2686
0.036
0.3047
1,267.8563
0.147579
-439.10253
-439.093529
-439.092585
-439.137615
31.722
CC(C#N)C1OCCO1
CC(C#N)C1OCCO1
true
CCC(C)C1CCCC1
C1COCO1
127.143
30.469
0.51898
3
0
45,320
3.025
1.53937
1.13253
3.7557
78.33
-0.2402
0.0119
0.2521
1,076.5275
0.15034
-401.986895
-401.979503
-401.978559
-402.01895
28.784
O=C1CC2CC=CCN12
O=C1CC2CC=CCN12
true
CC1CC2CCCCC12
O=C1CC2CC=CCN12
123.155
33.875
0.5472
1
0
1,344
4.3186
2.40191
2.35399
1.9532
60.01
-0.2445
0.0284
0.2729
675.5047
0.136875
-325.805017
-325.798027
-325.797083
-325.835879
25.922
CC1(C)CN=CO1
CC1(C)CN=CO1
true
CC1(C)CCCC1
C1=NCCO1
99.133
28.523
0.8235
2
0
25,163
3.2768
1.2402
0.97713
3.8754
63.6
-0.2369
0.0006
0.2374
1,127.7174
0.090018
-452.798536
-452.790935
-452.789991
-452.831862
26.913
O=C1OC=CN1CC#N
N#CCn1ccoc1=O
false
CCCC1CCCC1C
O=c1[nH]cco1
124.099
28.581
-0.03512
4
0
115,472
3.76863
0.97142
0.81277
1.8057
68.92
-0.2661
-0.0817
0.1844
1,350.7676
0.124163
-475.034538
-475.026034
-475.02509
-475.068681
29.91
OCC1COC(C=O)=N1
O=CC1=NC(CO)CO1
false
CCC1CCC(CC)C1
C1=NCCO1
129.115
30.3248
-1.0251
4
1
77,122
3.12334
1.15112
0.97709
1.4766
73.75
-0.2461
-0.0281
0.218
1,226.2383
0.146355
-439.048824
-439.039933
-439.038989
-439.083075
32.547
OC1C(CC11CN1)C=O
O=CC1CC2(CN2)C1O
false
CCC1CC2(CC2)C1C
C1CC2(C1)CN2
127.143
30.9115
-1.0919
3
2
61,416
2.53034
1.1385
0.88628
7.3482
73.38
-0.2391
0.0034
0.2424
1,330.564
0.158911
-456.402498
-456.392787
-456.391843
-456.437568
35.681
CC(CC([O-])=O)C(N)=[NH2+]
CC(CC(=O)[O-])C(N)=[NH2+]
false
CC(C)CC(C)C(C)C
130.147
29.9078
-3.1212
2
2
125,786
3.62047
1.5943
1.11456
3.7478
65.17
-0.2653
-0.035
0.2304
999.0787
0.090276
-452.705399
-452.698711
-452.697767
-452.736573
25.2
CC1=NOC2=C1C=NO2
Cc1noc2oncc12
false
CC1CCC2CCCC12
c1noc2oncc12
124.099
28.807
1.12422
4
0
108,171
2.64771
1.41687
1.22927
1.7475
79.49
-0.2258
0.0054
0.2313
1,114.2269
0.171064
-403.121482
-403.11276
-403.111816
-403.154885
33.485
CN1C2C=CCC12CO
CN1C2C=CCC21CO
false
CCC12CCCC1C2C
C1=CC2NC2C1
125.171
35.1248
-0.0086
2
1
61,082
3.81388
0.76388
0.71722
2.2133
75.78
-0.2455
-0.0716
0.1739
1,563.1091
0.132535
-455.168244
-455.158115
-455.157171
-455.204517
35.032
CC(C=O)N=C(N)C=O
CC(C=O)N=C(N)C=O
true
CCC(C)CC(C)CC
128.131
33.2124
-0.8701
3
1
77,960
3.33484
1.20321
0.99506
3.186
77.17
-0.2735
0.0248
0.2983
1,191.1182
0.147626
-401.903735
-401.89516
-401.894216
-401.936935
32.269
CC1C2C(O)C1C2C#N
CC1C2C(O)C1C2C#N
true
CCC1C2C(C)C1C2C
C1C2CC1C2
123.155
31.2538
0.38278
2
1
99,036
4.71022
0.73907
0.64647
2.8489
79.95
-0.2507
-0.0165
0.2343
1,712.917
0.156844
-456.380802
-456.3702
-456.369256
-456.417658
36.479
CN=C(C)NC(=O)CO
CN=C(C)NC(=O)CO
true
CCC(C)CC(C)CC
130.147
34.2615
-0.8569
3
2
38,247
3.1784
1.79985
1.47739
3.0217
73.86
-0.2493
0.0822
0.3315
935.0198
0.162512
-423.000657
-422.993943
-422.992999
-423.031846
27.694
C1C2CC11CCOC1O2
C1CC23CC(C2)OC3O1
false
C1CC2CC3CC2(C1)C3
C1CC23CC(C2)OC3O1
126.155
30.897
0.9118
2
0
50,744
2.36233
1.59311
1.06013
4.6248
66.71
-0.247
-0.0269
0.2201
1,103.8766
0.12462
-475.056315
-475.048191
-475.047247
-475.089692
29.468
O=CC1OCCNC1=O
O=CC1OCCNC1=O
true
CCC1CCCCC1C
O=C1COCCN1
129.115
28.8137
-1.2997
3
1
36,121
4.07974
1.13653
1.00582
1.9712
77.71
-0.2455
-0.0007
0.2448
1,187.0165
0.134774
-384.64427
-384.636216
-384.635272
-384.677125
31.117
C#CCC12CC=CC1O2
C#CCC12CC=CC1O2
true
CCCC12CCCC1C2
C1=CC2OC2C1
120.151
34.811
1.1072
1
0
31,556
3.31622
1.16313
0.87156
2.9726
70.21
-0.1808
0.0407
0.2215
1,287.3134
0.124808
-471.230088
-471.221033
-471.220089
-471.263705
33.05
CNC1=NC(O)=C(N)O1
CNc1nc(O)c(N)o1
false
CCC1CC(C)C(C)C1
c1cocn1
129.119
32.1269
0.0041
5
3
32,767
3.26851
1.03307
0.8148
2.8915
77.26
-0.1854
0.0296
0.215
1,403.0135
0.148635
-435.289113
-435.279803
-435.278859
-435.324566
33.023
COCC1=C(N)N=CN1
COCc1[nH]cnc1N
false
CCCC1CCCC1C
c1c[nH]cn1
127.147
33.7131
0.1383
3
2
88,153
2.38074
1.38561
1.09389
1.2992
85.55
-0.2447
0.0906
0.3353
1,244.5264
0.205937
-388.292794
-388.283495
-388.282551
-388.327038
35.826
CC1CC11CCOC1C
CC1CC12CCOC2C
false
CC1CCCC12CC2C
C1CC2(CC2)CO1
126.199
36.245
1.8214
1
0
2,171
3.8518
2.93944
1.77902
2.1857
53
-0.234
-0.0338
0.2002
682.0474
0.114535
-361.721849
-361.715404
-361.71446
-361.752165
23.983
OC1CNCC1=O
O=C1CNCC1O
false
CC1CCCC1C
O=C1CCNC1
101.105
23.8835
-1.4804
3
2
107,541
1.92398
1.57228
1.02104
1.5306
79.25
-0.2363
-0.0319
0.2044
1,229.0438
0.169856
-403.11467
-403.105506
-403.104562
-403.149606
33.541
CCC12CN1CC2C=O
CCC12CN1CC2C=O
true
CCC1CC2CC12CC
C1CN2CC12
125.171
34.149
0.2795
2
0
12,979
2.89214
2.75637
1.66826
2.8748
63.37
-0.2502
-0.0624
0.1878
760.7215
0.10748
-382.551181
-382.544577
-382.543632
-382.581614
25.808
OC12CC1C=CC2=O
O=C1C=CC2CC12O
false
CC1CCC2CC12C
O=C1C=CC2CC12
110.112
27.2038
-0.1237
2
1
27,396
2.09114
2.02381
1.02867
6.2198
59.41
-0.2546
-0.0189
0.2356
1,036.8313
0.07879
-506.019349
-506.011912
-506.010968
-506.051536
27.336
NC1=NC(=O)N=C(O)O1
Nc1nc(=O)nc(O)o1
false
CC1CC(C)CC(C)C1
O=c1ncocn1
129.075
26.6452
-1.2824
6
2
99,840
2.10019
1.36919
1.20489
5.4239
70.22
-0.2443
-0.0065
0.2377
1,140.1765
0.134959
-451.32345
-451.313378
-451.312434
-451.35829
36.799
NCC(O)(C#N)C(N)=N
N#CC(O)(CN)C(=N)N
false
CCC(C)(CC)C(C)C
128.135
31.5313
-1.86425
4
4
114,727
2.80437
1.44314
1.15047
3.9246
67.64
-0.2518
-0.0449
0.2068
1,076.0337
0.136308
-458.964226
-458.956287
-458.955343
-458.997093
29.933
OCC1CC2OC2C1=O
O=C1C(CO)CC2OC12
false
CCC1CC2CC2C1C
O=C1CCC2OC12
128.127
28.8608
-0.6649
3
1
87,020
2.11417
1.58848
1.05482
3.1517
76.44
-0.2487
0.0093
0.258
1,160.5166
0.134189
-417.991874
-417.982328
-417.981384
-418.025954
35.352
CC1NC1(C#C)C(N)=O
C#CC1(C(N)=O)NC1C
false
CCC1(C(C)C)CC1C
C1CN1
124.143
33.3561
-1.1646
2
2
71,686
2.74662
2.28477
1.70309
1.1264
73.66
-0.2194
0.067
0.2864
846.4092
0.150177
-401.879726
-401.873344
-401.8724
-401.909965
27.424
OC12CC3C1C1CC2N31
OC12CC3C1C1CC2N13
false
CC12CC3C4C(CC41)C32
C1C2C3C1N1C2CC31
123.155
30.8768
-0.4239
2
1
132,294
2.05322
1.88075
0.98194
3.0227
67.58
-0.2136
-0.0297
0.1839
1,084.5329
0.089751
-494.07932
-494.071895
-494.070951
-494.11124
28.299
NC1=CC(=N)OC(F)=N1
N=c1cc(N)nc(F)o1
false
CC1CC(C)CC(C)C1
N=c1ccnco1
129.094
26.7281
-0.12463
4
2
34,625
3.57573
1.25085
0.95003
5.6408
75.32
-0.2684
-0.0494
0.219
1,170.0504
0.113324
-416.81102
-416.803076
-416.802132
-416.844225
28.602
N#CC1=NCC=CCO1
N#CC1=NCC=CCO1
true
CCC1CCCCCC1
C1=CCOC=NC1
122.127
33.007
0.49488
3
0
117,970
3.36542
0.86979
0.73214
3.8824
74.2
-0.2339
0.0136
0.2475
1,577.8141
0.16835
-477.406903
-477.396246
-477.395302
-477.4436
37.061
COCC(O)C(=N)OC
COCC(O)C(=N)OC
true
CCCC(C)C(C)CC
133.147
32.6185
-0.38263
4
2
87,882
3.10934
1.27996
1.25747
1.7142
75.53
-0.235
0.0651
0.3002
1,100.5771
0.159125
-422.964238
-422.956149
-422.955205
-422.997143
31.288
OC1CC11CC2COC12
OC1CC12CC1COC12
false
CC1CC12CC1CCC12
C1OC2C1CC21CC1
126.155
30.9038
0.1561
2
1
40,271
2.98854
1.41112
1.08909
2.137
82.28
-0.2283
0.0273
0.2557
1,153.1961
0.172932
-403.145066
-403.137102
-403.136158
-403.177631
31.45
C1CC11CCCOC=N1
C1=NC2(CCCO1)CC2
false
C1CCCC2(CC1)CC2
C1=NC2(CCCO1)CC2
125.171
35.643
1.3577
2
0
9,430
6.6865
0.77255
0.72149
3.2363
69.04
-0.2577
0.0739
0.3317
1,583.9745
0.174869
-423.265024
-423.255015
-423.254071
-423.300549
34.966
CCOCC(O)CO
CCOCC(O)CO
true
CCCCC(C)CC
120.148
29.5856
-0.6239
3
2
114,886
3.83812
1.09572
0.96503
2.4514
77.88
-0.2424
0.0009
0.2434
1,257.3709
0.160203
-422.989858
-422.981743
-422.980798
-423.022881
31.098
OCC1OC2CCC=C12
OCC1OC2CCC=C12
true
CCC1CC2CCCC12
C1=C2COC2CC1
126.155
33.0638
0.4663
2
1
58,252
2.41083
1.10466
0.9385
1.4807
81.8
-0.2601
0.0731
0.3332
1,398.0725
0.202636
-425.415092
-425.404128
-425.403184
-425.451533
39.994
CC(O)C(C)C1OC1C
CC(O)C(C)C1OC1C
true
CC(C)C(C)C1CC1C
C1CO1
130.187
35.1798
0.7906
2
1
82,785
3.51798
1.7191
1.47812
2.3912
72.94
-0.226
0.0725
0.2984
914.7412
0.150692
-401.892597
-401.886164
-401.885219
-401.923045
27.239
OC1C2CC3C4C1C2N34
OC1C2CC3C4C1C2N34
true
CC1C2CC3C4C1C2C34
C1C2CC3C4C1C2N34
123.155
30.8068
-0.568
2
1
96,991
2.75205
1.35378
1.12441
2.1372
82.2
-0.2429
0.0343
0.2772
1,193.4136
0.170183
-403.138288
-403.129131
-403.128187
-403.172419
33.572
CN=C1OC2CCC12C
CN=C1OC2CCC12C
true
CCC1CC2CCC12C
N=C1OC2CCC12
125.171
35.573
1.2136
2
0
16,200
3.35007
2.45062
1.56128
3.9663
60.34
-0.226
-0.032
0.194
770.2675
0.096059
-398.613231
-398.606678
-398.605734
-398.643855
24.764
O=C1NC=CC11CO1
O=C1NC=CC12CO2
false
CC1CCCC12CC2
O=C1NC=CC12CO2
111.1
25.9657
-0.6011
2
1
85,516
2.4805
1.58798
1.08318
3.2037
80.43
-0.2415
0.0285
0.27
1,151.9133
0.172592
-403.158009
-403.149878
-403.148933
-403.190593
32.163
CC1CC(=N)OC2CC12
CC1CC(=N)OC2CC12
true
CC1CC(C)C2CC2C1
N=C1CCC2CC2O1
125.171
34.4877
1.40857
2
1
83,849
2.12325
1.89486
1.30534
4.1706
75.76
-0.2321
0.0106
0.2426
1,037.4075
0.161798
-419.215876
-419.207765
-419.206821
-419.248501
31.221
CN1C2CCNC(=O)C12
CN1C2CCNC(=O)C21
false
CC1CCCC2C(C)C12
O=C1NCCC2NC12
126.159
32.9657
-0.8111
2
1
96,276
2.08788
1.86131
1.15257
3.7899
76.14
-0.2528
0.0405
0.2934
1,117.0071
0.172278
-440.305645
-440.297092
-440.296148
-440.33899
32.69
CC1CCCOC(=N)O1
CC1CCCOC(=N)O1
true
CC1CCCCC(C)C1
N=C1OCCCCO1
129.159
33.4597
1.13667
3
1
120,646
4.34916
0.71602
0.67881
1.5142
84.48
-0.2458
0.0829
0.3287
1,774.7231
0.202242
-425.390318
-425.379257
-425.378313
-425.426947
39.255
COCC1CC1(C)OC
COCC1CC1(C)OC
true
CCCC1CC1(C)CC
C1CC1
130.187
35.397
1.0578
2
0
129,812
3.19267
1.39362
0.97371
4.2216
80.18
-0.1866
-0.0105
0.1761
1,152.7284
0.127529
-430.259727
-430.25154
-430.250596
-430.291972
32.193
NC1=CC(=N)C(N)=NN1
N=c1cc(N)[nH]nc1N
false
CC1CCC(C)C(C)C1
N=c1cc[nH]nc1
125.135
33.2672
-0.94643
4
4
6,434
4.55725
1.35847
1.26425
0.6571
59.34
-0.2552
-0.0496
0.2056
947.2085
0.103978
-419.690936
-419.683287
-419.682342
-419.723413
28.051
OC1(CC(=O)C1)C=O
O=CC1(O)CC(=O)C1
false
CCC1(C)CC(C)C1
O=C1CCC1
114.1
25.2548
-0.7207
3
1
131,659
1.72911
0.96018
0.62814
3.357
62.35
-0.2658
-0.0644
0.2014
1,622.4534
0.08206
-489.943463
-489.932043
-489.931098
-489.986668
33.814
OCC1=CC(=O)N=NO1
O=c1cc(CO)onn1
false
CCC1CCCC(C)C1
O=c1cconn1
128.087
26.4908
-1.0779
5
1
99,601
2.06987
1.34028
0.96266
1.2034
83.88
-0.2567
0.0493
0.306
1,323.2988
0.17903
-387.044674
-387.034313
-387.033369
-387.080128
38.255
CCC(C#C)C1(C)CO1
C#CC(CC)C1(C)CO1
false
CCC(CC)C1(C)CC1
C1CO1
124.183
36.971
1.4347
1
0
65,565
3.24052
1.02435
0.95411
1.9071
82.4
-0.2335
0.0782
0.3117
1,357.302
0.193226
-404.30013
-404.290702
-404.289758
-404.335066
35.029
CC1(CN2CC2)CCO1
CC1(CN2CC2)CCO1
true
CC1(CC2CC2)CCC1
C1CC(CN2CC2)O1
127.187
35.414
0.481
2
0
124,858
3.59509
1.31869
1.05108
2.3615
77.56
-0.2361
0.0095
0.2455
1,148.8201
0.149739
-398.150449
-398.14243
-398.141485
-398.183629
30.483
CC1(CC1)C1=NNC=N1
CC1(c2nc[nH]n2)CC1
false
CC1(C2CCCC2)CC1
c1nc(C2CC2)n[nH]1
123.159
32.9687
0.8562
2
1
98,930
4.3244
0.83211
0.70745
6.4449
72.92
-0.2577
-0.0461
0.2116
1,529.6893
0.110132
-453.963951
-453.95392
-453.952976
-454.000458
33.816
CNC(=O)NC(=O)C#C
C#CC(=O)NC(=O)NC
false
CCC(C)CC(C)CC
126.115
31.4314
-0.9248
2
2
29,064
2.67875
1.6564
1.02351
4.7533
83.63
-0.2191
-0.0658
0.1533
1,087.7383
0.11483
-420.674334
-420.667113
-420.666169
-420.706223
28.013
OC1=CC=CC=CC1=O
O=c1cccccc1O
false
CC1CCCCCC1C
O=c1cccccc1
122.123
34.3768
0.7524
2
1
106,664
2.61526
1.18291
1.01483
1.3884
79.02
-0.2466
0.0693
0.3159
1,269.6977
0.181126
-424.194226
-424.18454
-424.183595
-424.228508
36.659
CC12CC1(CO)CC2O
CC12CC1(CO)CC2O
true
CCC12CC(C)C1(C)C2
C1CC2CC12
128.171
32.8666
0.1397
2
2
55,244
4.04861
0.96423
0.91404
4.8248
70.73
-0.2563
0.0097
0.266
1,292.4338
0.137333
-455.202099
-455.193436
-455.192492
-455.236446
31.414
NC(=O)C1COC(=N)C1
N=C1CC(C(N)=O)CO1
false
CC1CCC(C(C)C)C1
N=C1CCCO1
128.131
30.9801
-0.51453
3
2
38,742
2.87464
2.07897
1.97338
0.5147
74.7
-0.2078
0.0004
0.2082
823.134
0.152055
-401.918199
-401.91231
-401.911366
-401.94793
26.096
C1C2OC3CN1C2C=C3
C1=CC2C3CN2CC1O3
false
C1CC2C3CC1CC2C3
C1=CC2C3CN2CC1O3
123.155
33.162
0.0078
2
0
132,616
3.16442
1.29395
0.91931
2.0483
72.89
-0.1906
0.005
0.1956
1,162.2357
0.113184
-461.976456
-461.968695
-461.967751
-462.008295
30.689
NC1=CC=C(F)C=C1O
Nc1ccc(F)cc1O
false
CC1CCC(C)C(C)C1
c1ccccc1
127.118
32.4772
1.1135
2
2
101,273
2.59665
0.96542
0.88173
3.6752
79.91
-0.2945
-0.0026
0.2919
1,438.1214
0.168912
-403.147413
-403.13739
-403.136446
-403.183039
35.802
CCC(C)C1OC1C#N
CCC(C)C1OC1C#N
true
CCC(C)C1CC1CC
C1CO1
125.171
33.729
1.32348
2
0
60,772
4.46724
0.89461
0.74886
1.9723
67.87
-0.2783
-0.0397
0.2385
1,418.6908
0.111161
-491.143581
-491.134299
-491.133355
-491.17856
31.228
CN(C=O)C(=O)OC=N
CN(C=O)C(=O)OC=N
true
CCCC(C)C(C)CC
130.103
29.0917
-0.18173
4
1
57,268
2.11494
1.6286
1.23398
2.6214
75.04
-0.2596
0.01
0.2696
1,099.2211
0.157155
-419.194565
-419.184762
-419.183818
-419.228639
36.727
CC(O)(C#N)C1(C)CN1
CC(O)(C#N)C1(C)CN1
true
CCC(C)(C)C1(C)CC1
C1CN1
126.159
32.6445
-0.37712
3
2
76,538
2.78683
1.21587
1.17212
3.2374
66.82
-0.2382
0.0306
0.2688
1,112.4201
0.123306
-475.007209
-474.9984
-474.997456
-475.041063
31.9
OC1C(O)C11CNC1=O
O=C1NCC12C(O)C2O
false
CC1CCC12C(C)C2C
O=C1NCC12CC2
129.115
27.4563
-2.162
3
3
18,876
3.15916
2.4912
2.10485
1.7284
66.06
-0.2357
0.0612
0.2969
737.197
0.145055
-363.830219
-363.823836
-363.822892
-363.860403
25.726
OC1C2C3CCC1N23
OC1C2CCC3C1N23
false
CC1C2CCC3C1C23
C1CC2C3CC1N23
111.144
28.4438
-0.4239
2
1
1,582
4.80833
2.14901
1.49881
0.3006
54.54
-0.2548
-0.1036
0.1512
756.6609
0.074554
-343.242553
-343.23493
-343.233986
-343.274929
25.448
CC(=O)C(=O)C#C
C#CC(=O)C(C)=O
false
CCC(C)C(C)C
96.085
24.521
-0.2223
2
0