index
int64
1
134k
A
float64
0
620k
B
float64
0.34
438
C
float64
0.33
283
mu
float64
0
29.6
alpha
float64
6.31
197
homo
float64
-0.43
-0.1
lumo
float64
-0.18
0.19
gap
float64
0.02
0.62
r2
float64
19
3.37k
zpve
float64
0.02
0.27
U0
float64
-714.57
-40.48
U
float64
-714.56
-40.48
H
float64
-714.56
-40.48
G
float64
-714.6
-40.5
Cv
float64
6
47
smiles
stringlengths
1
28
canonsmiles
stringlengths
1
34
isSmilesEqual
bool
2 classes
generic_scaffold
stringlengths
1
21
scaffold
stringlengths
0
31
rdkit_WT
float64
16
152
rdkit_MR
float64
3.61
43.7
rdkit_LogP
float64
-4.91
3.76
rdkit_HA
float64
0
7
rdkit_HD
float64
0
5
123,687
4.11958
1.63725
1.27356
2.4835
70.74
-0.2399
0.0039
0.2438
935.2065
0.116531
-416.808381
-416.80228
-416.801336
-416.838861
24.394
C1C2OC2C2=CC=NN12
c1cc2n(n1)CC1OC21
false
C1CC2CC3CC3C2C1
c1cc2n(n1)CC1OC21
122.127
29.841
0.3366
3
0
96,126
2.14151
1.80709
1.22473
2.5182
82.05
-0.236
0.0716
0.3076
1,125.0732
0.195295
-404.34129
-404.332523
-404.331579
-404.374122
34.646
CC1OCCC2NC12C
CC1OCCC2NC21C
false
CC1CCCC2CC12C
C1CC2NC2CO1
127.187
35.3597
0.5257
2
1
74,043
2.68277
1.53131
1.03988
1.6127
85.84
-0.2258
0.0237
0.2495
1,194.6873
0.184242
-387.114798
-387.106407
-387.105462
-387.147935
32.074
CC1=C2CCOC2CC1
CC1=C2CCOC2CC1
true
CC1CCC2CCCC12
C1=C2CCOC2CC1
124.183
36.291
1.8856
1
0
96,070
2.57495
1.52973
1.10754
1.0071
74.5
-0.2453
0.0673
0.3125
1,136.498
0.171782
-440.259671
-440.251053
-440.250109
-440.292542
33.391
CC12COCC(O)C1N2
CC12COCC(O)C1N2
true
CC1CCCC2(C)CC12
C1CC2NC2CO1
129.159
32.1545
-0.892
3
2
39,504
2.34533
1.77757
1.21799
1.0788
78.33
-0.2193
0.0775
0.2968
1,085.7032
0.184545
-424.194526
-424.186595
-424.18565
-424.226664
31.985
C1C2OCCCCOC12
C1CCOC2CC2OC1
false
C1CCCC2CC2CC1
C1CCOC2CC2OC1
128.171
33.331
0.9543
2
0
79,109
2.86602
1.70362
1.27582
1.515
67.87
-0.2381
-0.0221
0.216
968.6025
0.12513
-437.85194
-437.844894
-437.84395
-437.88334
27.917
OC1C2C3C1C(=O)CN23
O=C1CN2C3C(O)C1C32
false
CC1CC2C3C(C)C1C23
O=C1CN2C3CC1C32
125.127
28.7858
-1.3874
3
1
36,362
5.01294
0.74606
0.6999
2.1654
83.12
-0.2578
0.0511
0.309
1,630.1164
0.157076
-385.818855
-385.809566
-385.808621
-385.854016
34.176
C#CCC1OC1C1CC1
C#CCC1OC1C1CC1
true
CCCC1CC1C1CC1
C1CC1C1CO1
122.167
34.835
1.1871
1
0
1,397
6.67352
1.45114
1.24798
0.6891
58.34
-0.3343
0.0003
0.3346
888.8668
0.101478
-303.533559
-303.526088
-303.525144
-303.565337
25.55
CC(CC#N)C#N
CC(C#N)CC#N
false
CCCC(C)CC
94.117
25.007
1.05976
2
0
64,576
2.78865
1.48501
1.28006
3.3131
63.56
-0.2583
-0.067
0.1913
992.0133
0.099206
-473.798443
-473.790626
-473.789682
-473.830941
28.803
OC1(C=O)C2CN2C1=O
O=CC1(O)C(=O)N2CC21
false
CCC1(C)C(C)C2CC21
O=C1CC2CN12
127.099
26.5148
-1.8592
3
1
115,092
2.57814
1.47914
1.08519
4.207
73.97
-0.226
-0.0161
0.2099
1,124.3354
0.149632
-439.131781
-439.123494
-439.12255
-439.165038
31.408
OCC1CC=CNC1=O
O=C1NC=CCC1CO
false
CCC1CCCCC1C
O=C1CCC=CN1
127.143
32.4755
-0.3715
2
2
88,808
3.27367
1.08457
0.89553
3.5445
72.89
-0.2399
0.0054
0.2453
1,298.2353
0.147304
-439.070672
-439.062089
-439.061145
-439.10481
31.092
CN1CC1C1COC1=O
CN1CC1C1COC1=O
true
CC1CCC1C1CC1C
O=C1OCC1C1CN1
127.143
30.867
-0.5266
3
0
114,004
3.96213
0.69523
0.67362
4.8946
77.45
-0.2622
0.0136
0.2758
1,732.9437
0.169742
-440.282935
-440.273003
-440.272059
-440.319311
34.731
CCC1NC1COC=O
CCC1NC1COC=O
true
CCCCC1CC1CC
C1CN1
129.159
33.0187
-0.0902
3
1
15,171
8.23759
0.64481
0.62671
0.1907
86.99
-0.2255
0.0573
0.2828
1,858.4337
0.176087
-311.839511
-311.830025
-311.82908
-311.877487
33.347
CCCC#CC1CC1
CCCC#CC1CC1
true
CCCCCC1CC1
C1CC1
108.184
35.408
2.1999
0
0
41,541
4.02523
1.52657
1.42587
2.1873
76.97
-0.226
0.0769
0.3028
962.2572
0.162022
-385.816952
-385.810592
-385.809648
-385.847586
27.003
C1CC2C1C1C3OC1C23
C1CC2C1C1C3OC1C23
true
C1CC2C1C1C3CC1C23
C1CC2C1C1C3OC1C23
122.167
31.855
1.0396
1
0
63,002
2.39521
1.78318
1.55639
2.1469
81.08
-0.2184
0.0734
0.2918
1,002.554
0.183532
-383.22751
-383.219424
-383.21848
-383.259295
33.306
CC1(C)C2NC2C2CN12
CC1(C)C2NC2C2CN21
false
CC1(C)C2CC2C2CC21
C1C2NC2C2CN12
124.187
35.2847
-0.1968
2
1
130,432
6.59004
0.88777
0.79543
4.1157
77.22
-0.2365
-0.0091
0.2274
1,380.791
0.114495
-412.976362
-412.968123
-412.967178
-413.009446
30.204
[NH3+]CC1=N[N-]C(=N1)C#C
C#Cc1nc(C[NH3+])n[n-]1
false
CCC1CCC(CC)C1
c1nc[n-]n1
122.131
29.8791
-1.843
2
1
15,939
3.2777
1.70931
1.40062
0.1446
81.17
-0.2559
0.0794
0.3352
1,014.3309
0.201082
-313.053618
-313.045326
-313.044382
-313.08694
31.861
CCC12CCC1CC2
CCC12CCC1CC2
true
CCC12CCC1CC2
C1CC2CCC12
110.2
34.682
2.5866
0
0
108,044
3.57771
1.31485
1.18865
1.608
84.81
-0.2021
0.0748
0.2769
1,151.3802
0.195798
-367.157047
-367.149051
-367.148107
-367.189426
32.187
CCC12CC3CN(C1)C23
CCC12CC3CN(C1)C32
false
CCC12CC3CC(C1)C32
C1C2CN3CC1C23
123.199
36.192
1.1005
1
0
126,059
3.02151
1.62634
1.11701
3.978
72.12
-0.2346
-0.041
0.1936
1,047.6267
0.124637
-434.032967
-434.024872
-434.023928
-434.06616
29.125
CC1NCC2=C1ON=N2
CC1NCc2nnoc21
false
CC1CCC2CCCC12
C1NCc2onnc21
125.131
29.5527
0.2338
4
1
27,110
2.91078
1.21793
0.91178
2.3277
79.07
-0.1827
-0.0217
0.161
1,246.6318
0.136196
-418.046374
-418.03724
-418.036296
-418.081594
32.568
NC1=C(CC=O)NC=C1
Nc1cc[nH]c1CC=O
false
CCCC1CCCC1C
c1cc[nH]c1
124.143
34.9731
0.3383
2
2
30,728
3.03409
1.18283
0.9089
1.8383
80.17
-0.1933
0.0294
0.2227
1,328.9704
0.157665
-423.064694
-423.054806
-423.053862
-423.099974
35.165
CCC1=C(O)C(C)=CO1
CCc1occ(C)c1O
false
CCC1CCC(C)C1C
c1ccoc1
126.155
34.4878
1.85602
2
1
20,704
3.3937
2.39892
1.41759
0.9658
63.21
-0.2477
-0.0756
0.172
811.9164
0.097287
-394.820159
-394.813471
-394.812527
-394.85112
24.454
CC1=NC=NNC1=O
Cc1ncn[nH]c1=O
false
CC1CCCCC1C
O=c1cncn[nH]1
111.104
27.3897
-0.52668
3
1
12,616
3.17491
2.21923
1.36569
2.2149
50.99
-0.2693
-0.0572
0.2122
817.4386
0.082821
-455.654547
-455.647579
-455.646635
-455.686029
24.907
OC1C(=O)COC1=O
O=C1COC(=O)C1O
false
CC1CCC(C)C1C
O=C1COC(=O)C1
116.072
21.9728
-1.5268
4
1
19,409
3.02994
2.28643
1.69091
1.9302
68.29
-0.2374
0.0636
0.3011
821.4721
0.142167
-363.792648
-363.785416
-363.784471
-363.823745
28.314
OC1C2CN2C11CC1
OC1C2CN2C12CC2
false
CC1C2CC2C12CC2
C1C2CC3(CC3)N12
111.144
28.4658
-0.4223
2
1
80,492
2.20456
1.44097
1.24467
3.2065
78.02
-0.2676
0.0136
0.2812
1,112.0411
0.147599
-401.938286
-401.929558
-401.928613
-401.971381
32.919
CC1C2CC(O)C12C#N
CC1C2CC(O)C12C#N
true
CCC12C(C)CC1C2C
C1CC2CC12
123.155
31.3238
0.52688
2
1
29,194
3.18369
1.4212
0.98856
4.7996
71.96
-0.2298
-0.0386
0.1912
1,125.8851
0.114563
-454.03763
-454.029896
-454.028951
-454.069942
29.122
CC1=CNC(=O)N=C1O
Cc1c[nH]c(=O)nc1O
false
CC1CCC(C)C(C)C1
O=c1nccc[nH]1
126.115
31.2595
-0.21608
3
2
3,644
10.31353
2.0564
1.71454
2.1395
52.68
-0.2707
-0.0435
0.2273
646.8846
0.056456
-334.36233
-334.35697
-334.356026
-334.391449
19.064
C#CC1=NNN=N1
C#Cc1nn[nH]n1
false
CCC1CCCC1
c1nn[nH]n1
94.077
22.1127
-0.819
3
1
73,293
2.88856
1.81862
1.30764
0.1903
78.74
-0.2338
0.0824
0.3162
1,019.5866
0.1715
-403.095416
-403.087552
-403.086607
-403.127046
31.981
CC12COC3(C)C1NC23
CC12COC3(C)C1NC23
true
CC12CCC3(C)C1CC23
C1OC2C3NC2C13
125.171
33.1757
0.1356
2
1
27,009
3.26673
1.18601
0.90746
2.2004
68.35
-0.2144
0.0121
0.2265
1,194.624
0.102571
-432.920815
-432.9128
-432.911855
-432.954466
28.882
OC1=C(CC#N)NC=N1
N#CCc1[nH]cnc1O
false
CCCC1CCCC1C
c1c[nH]cn1
123.115
29.5695
0.18138
3
2
66,369
2.22723
1.37451
1.29871
1.2578
83.31
-0.2594
0.0365
0.2959
1,149.9846
0.182703
-387.080669
-387.071704
-387.07076
-387.113606
35.764
OC1(CCCCC1)C#C
C#CC1(O)CCCCC1
false
CCC1(C)CCCCC1
C1CCCCC1
124.183
36.8678
1.3148
1
1
1,622
3.83134
2.09958
1.4405
3.9686
57.69
-0.2705
0.0278
0.2983
825.7495
0.124257
-341.839596
-341.831335
-341.83039
-341.871873
29.255
CC(O)C(N)C#N
CC(O)C(N)C#N
true
CCC(C)C(C)C
100.121
25.2692
-0.78192
3
2
89,170
1.97653
1.60851
1.05458
3.5544
77.87
-0.2301
-0.0199
0.2102
1,196.3442
0.156819
-423.00297
-422.993864
-422.99292
-423.036726
33.809
CC1OC2(C)C(C=O)C12
CC1OC2(C)C(C=O)C12
true
CCC1C2C(C)CC12C
C1OC2CC12
126.155
31.996
0.6087
2
0
123,021
5.12648
0.54779
0.52474
1.0402
84.24
-0.2427
0.0799
0.3226
2,184.9428
0.203445
-425.400426
-425.389537
-425.388593
-425.437986
38.504
CCCOCC1CC1O
CCCOCC1CC1O
true
CCCCCC1CC1C
C1CC1
130.187
35.2238
0.7938
2
1
74,606
3.07935
1.80183
1.44467
0.1941
84.73
-0.2112
0.0187
0.23
965.2869
0.161576
-348.758438
-348.75143
-348.750486
-348.789398
29.333
CC1=CC2C3C=CC1C23
CC1=CC2C3C=CC1C32
false
CC1CC2C3CCC1C32
C1=CC2C3C=CC1C23
118.179
36.857
1.9945
0
0
79,869
2.96141
1.56659
1.35473
0.8375
74.43
-0.2281
0.0714
0.2995
1,021.1157
0.159661
-422.984068
-422.976227
-422.975283
-423.015926
31.187
CC1C2C3COC2C13O
CC1C2C3COC2C13O
true
CC1C2C3CCC2C13C
C1OC2C3CC2C13
126.155
30.8338
0.012
2
1
77,901
2.07417
1.57494
1.37281
1.7594
70.92
-0.2454
0.0624
0.3078
1,064.6336
0.157285
-460.120333
-460.110753
-460.109808
-460.154143
35.968
CC1C2C(O)C(O)C12O
CC1C2C(O)C(O)C12O
true
CC1C(C)C2(C)C(C)C12
C1CC2CC12
130.143
29.6174
-1.2812
3
3
116,846
6.70594
0.49418
0.46558
4.2332
85.8
-0.2566
-0.0465
0.2101
2,368.4633
0.15501
-423.00228
-422.991169
-422.990225
-423.041188
36.579
CCC(=O)C#CCOC
CCC(=O)C#CCOC
true
CCCCCC(C)CC
126.155
34.95
0.6153
2
0
66,635
3.47863
1.84642
1.67802
2.3667
68.85
-0.2622
0.0905
0.3527
861.5529
0.138358
-421.801537
-421.795351
-421.794407
-421.831812
26.083
CC12C3C1C1OC3C2O1
CC12C3OC4OC3C1C42
false
CC12C3CC4CC3C1C42
O1C2OC3C1C1C2C31
124.139
28.621
0.376
2
0
46,082
4.90169
1.03548
0.88715
2.8366
80.8
-0.2556
-0.0393
0.2164
1,255.4924
0.124903
-400.732193
-400.724248
-400.723304
-400.764825
30.276
N=C1OCC(C=C1)C#C
C#CC1C=CC(=N)OC1
false
CCC1CCC(C)CC1
N=C1C=CCCO1
121.139
35.1417
0.79947
2
1
111,192
2.77742
1.17205
0.94055
3.9362
73.61
-0.2587
0.0103
0.269
1,239.7365
0.136915
-417.935025
-417.926837
-417.925893
-417.968322
30.463
OCC1C2NC1C2C#N
N#CC1C2NC1C2CO
false
CCC1C2CC1C2CC
C1C2CC1N2
124.143
30.3905
-0.91132
3
2
125,021
2.37344
1.86151
1.05037
5.9594
73.29
-0.2258
-0.0566
0.1692
1,071.5846
0.11234
-453.968602
-453.960307
-453.959363
-454.001433
30.671
CC1=C(N)C(=O)ON=C1
Cc1cnoc(=O)c1N
false
CC1CCCC(C)C1C
O=c1cccno1
126.115
31.9224
-0.07458
4
1
27,044
2.52444
1.48624
0.93608
7.3669
68.75
-0.223
-0.0486
0.1744
1,143.9694
0.088576
-489.909692
-489.901771
-489.900827
-489.942319
28.979
NC1=C(OC(=N)O1)C=O
N=c1oc(N)c(C=O)o1
false
CCC1CC(C)CC1C
N=c1occo1
128.087
26.6286
-0.25323
5
2
56,607
3.15173
0.93447
0.93241
3.854
68.88
-0.2702
0.0149
0.285
1,323.988
0.135092
-455.112155
-455.102788
-455.101844
-455.146819
33.615
OC(C#N)C(O)C1CN1
N#CC(O)C(O)C1CN1
false
CCC(C)C(C)C1CC1
C1CN1
128.131
29.4173
-1.79642
4
3
118,021
3.5671
0.81247
0.68999
6.165
77.01
-0.2774
0.0398
0.3172
1,629.3511
0.168532
-440.287785
-440.277116
-440.276172
-440.324073
37.326
COCC(O)C(C)C#N
COCC(O)C(C)C#N
true
CCCC(C)C(C)CC
129.159
32.6598
0.15338
3
1
28,573
5.22473
0.97335
0.88188
1.4822
81.59
-0.2148
0.0143
0.2291
1,356.0345
0.148467
-401.983986
-401.975695
-401.97475
-402.017692
30.569
CC1=CN=C(O1)C1CC1
Cc1cnc(C2CC2)o1
false
CC1CCC(C2CC2)C1
c1coc(C2CC2)n1
123.155
33.215
1.86042
2
0
87,056
2.25611
1.462
1.09356
2.8347
69.48
-0.2856
-0.0031
0.2825
1,138.2913
0.121997
-437.850559
-437.841745
-437.840801
-437.884472
31.447
CC1OC1(C#N)C1CO1
CC1OC1(C#N)C1CO1
true
CCC1(C2CC2)CC1C
C1OC1C1CO1
125.127
28.631
0.06628
3
0
10,052
3.34271
1.248
0.9754
2.6576
74.24
-0.2489
-0.0236
0.2254
1,207.7251
0.150112
-347.785125
-347.77548
-347.774535
-347.820256
33.566
CCC(CC#C)C=O
C#CCC(C=O)CC
false
CCCC(CC)CC
110.156
33.295
1.2348
1
0
110,796
2.8263
1.40212
1.21396
4.1306
60.13
-0.2768
0.0288
0.3056
1,035.9167
0.112975
-494.914674
-494.907061
-494.906117
-494.947912
27.909
OCC1C2OC(=O)OC12
O=C1OC2C(CO)C2O1
false
CCC1C2CC(C)CC12
O=C1OC2CC2O1
130.099
25.7178
-0.4875
4
1
28,028
6.12538
0.89306
0.7837
1.8799
72.92
-0.2078
0.0299
0.2377
1,376.9026
0.11246
-416.810587
-416.802197
-416.801253
-416.843936
31.194
NC1=NC(CC#C)=CO1
C#CCc1coc(N)n1
false
CCCC1CCC(C)C1
c1cocn1
122.127
33.4524
0.4325
3
1
6,299
4.1093
1.09018
0.96191
2.3407
74.46
-0.2464
-0.0163
0.2301
1,245.3007
0.14971
-347.800058
-347.790337
-347.789393
-347.835053
34.302
CC(CC(C)=O)C#C
C#CC(C)CC(C)=O
false
CCC(C)CC(C)C
110.156
33.295
1.2348
1
0
22,884
3.43946
1.18624
0.94895
2.1031
72.23
-0.2382
-0.0425
0.1958
1,188.9012
0.123751
-474.983553
-474.974974
-474.974029
-475.017003
32.178
ON=C1C=CC(O)C1O
ON=C1C=CC(O)C1O
true
CCC1CCC(C)C1C
N=C1C=CCC1
129.115
30.3751
-0.8918
4
3
61,239
2.98715
0.89701
0.76713
3.5778
79.76
-0.2742
0.0317
0.3059
1,509.5421
0.168793
-403.154136
-403.144035
-403.143091
-403.189995
35.933
CC(CC#N)C1OC1C
CC(CC#N)C1OC1C
true
CCCC(C)C1CC1C
C1CO1
125.171
33.729
1.32348
2
0
13,970
5.52733
1.07638
0.99994
0.2701
83.91
-0.2168
0.0474
0.2642
1,238.9471
0.15338
-310.622684
-310.614349
-310.613405
-310.657172
30.184
CC#CC12CC1CC2
CC#CC12CCC1C2
false
CCCC12CCC1C2
C1CC2CC12
106.168
33.224
1.8098
0
0
28,480
3.09243
1.41666
0.97941
2.451
81.41
-0.1911
-0.019
0.1722
1,173.7149
0.138054
-414.261386
-414.252902
-414.251958
-414.293973
32.701
CC1=NC(N)=NC=C1N
Cc1nc(N)ncc1N
false
CC1CCC(C)C(C)C1
c1cncnc1
124.147
35.5938
-0.05058
4
2
89,126
5.31329
0.56389
0.53677
4.6766
79.2
-0.2564
0.0261
0.2824
2,029.0617
0.1692
-440.257708
-440.247486
-440.246542
-440.295283
35.46
OC1CC1CCOC=N
N=COCCC1CC1O
false
CCCCCC1CC1C
C1CC1
129.159
33.4665
0.38097
3
2
65,486
2.9447
1.22214
1.01777
2.3516
76.33
-0.2753
0.0297
0.305
1,202.0277
0.146438
-401.935545
-401.9269
-401.925956
-401.969053
32.59
CC1(CC2(CO2)C1)C#N
CC1(C#N)CC2(CO2)C1
false
CCC1(C)CC2(CC2)C1
C1CC2(C1)CO2
123.155
31.637
1.07908
2
0
117,051
4.03258
0.76875
0.68238
1.3263
78.56
-0.237
-0.0576
0.1794
1,722.8024
0.168584
-440.348565
-440.337818
-440.336874
-440.386099
36.935
CCNC(=O)C(=O)CC
CCNC(=O)C(=O)CC
true
CCCC(C)C(C)CC
129.159
33.9817
0.1016
2
1
81,904
2.40566
1.86306
1.17432
3.6407
69.76
-0.2305
-0.0921
0.1384
1,023.4399
0.123722
-437.888799
-437.880904
-437.87996
-437.921285
29.654
CC1N2CC2C(=O)C1=O
CC1C(=O)C(=O)C2CN12
false
CC1C(C)C2CC2C1C
O=C1CN2CC2C1=O
125.127
29.97
-0.7891
3
0
39,302
2.61739
2.05245
1.78591
2.3218
72.52
-0.2313
0.0708
0.3021
875.6968
0.163325
-423.014714
-423.008347
-423.007403
-423.045216
26.94
C1CC2OCC3OC2C13
C1OC2CCC3C1OC23
false
C1CC2CCC3C1CC23
C1OC2CCC3C1OC23
126.155
31.125
0.5626
2
0
65,475
2.96389
1.1239
1.06795
2.1199
78.19
-0.2585
0.0831
0.3417
1,267.0975
0.179777
-424.193924
-424.184295
-424.183351
-424.228494
36.216
CC1(CC2(C)CO2)CO1
CC1(CC2(C)CO2)CO1
true
CC1(CC2(C)CC2)CC1
C1OC1CC1CO1
128.171
33.331
0.9543
2
0
12,305
3.01112
2.2254
1.33962
6.0137
62.52
-0.2392
-0.0591
0.18
877.4563
0.120666
-399.854777
-399.847674
-399.84673
-399.886573
26.237
O=C1CCCNC1=O
O=C1CCCNC1=O
true
CC1CCCCC1C
O=C1CCCNC1=O
113.116
27.2507
-0.5345
2
1
119,147
2.57654
1.0449
0.85882
0.8259
89.48
-0.227
0.0865
0.3135
1,517.4736
0.226121
-389.475311
-389.464292
-389.463348
-389.511679
41.068
CCOC1(CC1)C(C)C
CCOC1(C(C)C)CC1
false
CCCC1(C(C)C)CC1
C1CC1
128.215
38.429
2.2115
1
0
125,514
4.14467
1.0152
0.90066
3.004
68.63
-0.297
-0.0424
0.2546
1,264.4818
0.101485
-429.046174
-429.037921
-429.036977
-429.080786
27.848
CC1=NN(CC#N)N=N1
Cc1nnn(CC#N)n1
false
CCCC1CCC(C)C1
c1nn[nH]n1
123.119
28.167
-0.4949
5
0
4,798
6.85343
1.34147
1.13788
2.5329
64.13
-0.2145
0.0302
0.2447
1,033.6868
0.118626
-399.830731
-399.822925
-399.821981
-399.863136
27.449
COC1=NC(C)=CO1
COc1nc(C)co1
false
CCC1CCC(C)C1
c1cocn1
113.116
27.792
0.99162
3
0
6,164
3.57474
1.41549
1.27821
3.5488
69.68
-0.247
-0.0264
0.2205
1,050.1498
0.149816
-384.951734
-384.942479
-384.941535
-384.985565
33.084
CC(=O)C1OC1(C)C
CC(=O)C1OC1(C)C
true
CC(C)C1CC1(C)C
C1CO1
114.144
29.633
0.7528
2
0
21,901
3.68794
1.91239
1.25935
4.4227
55.42
-0.2554
-0.0607
0.1946
853.1249
0.073641
-430.726315
-430.719795
-430.718851
-430.757232
23.239
OC1=NNN=C1C=O
O=Cc1n[nH]nc1O
false
CCC1CCCC1C
c1cn[nH]n1
113.076
23.435
-0.6772
4
2
79,118
5.08636
1.19518
1.10183
3.9126
76.11
-0.2369
0.0157
0.2526
1,119.8932
0.149615
-401.93837
-401.931162
-401.930218
-401.96971
29.125
CC1C2C3NC(=O)C2C13
CC1C2C3NC(=O)C2C13
true
CC1CC2C3C(C)C2C13
O=C1NC2C3CC2C13
123.155
31.5647
-0.0033
1
1
27,827
2.0285
1.8872
0.98359
4.2801
68.67
-0.2451
-0.0507
0.1944
1,118.123
0.10084
-473.910668
-473.902886
-473.901942
-473.943209
28.735
CC1=NC(O)=CC(=O)O1
Cc1nc(O)cc(=O)o1
false
CC1CC(C)CC(C)C1
O=c1ccnco1
127.099
29.1748
0.04882
4
1
42,894
2.79712
1.54724
1.22609
3.745
72.45
-0.2429
-0.0205
0.2225
1,037.0246
0.13603
-421.787294
-421.779637
-421.778693
-421.81991
28.745
O=C1C2CC2C11COC1
O=C1C2CC2C12COC2
false
CC1C2CC2C12CCC2
O=C1C2CC2C12COC2
124.139
29.856
0.2218
2
0
25,316
2.39342
1.58906
0.955
1.964
74.16
-0.2604
-0.0862
0.1742
1,112.0772
0.07697
-435.491667
-435.484209
-435.483265
-435.524025
26.746
O=CC1=C(N=CO1)C#C
C#Cc1ncoc1C=O
false
CCC1CCCC1CC
c1cocn1
121.095
29.8255
0.4684
3
0
130,079
5.43868
1.36306
1.09236
4.2151
69.92
-0.202
0.0258
0.2278
1,024.2165
0.10519
-429.075153
-429.068325
-429.067381
-429.106073
26.79
NC1=NN2C=CN=C2N1
Nc1nn2ccnc2[nH]1
false
CC1CC2CCCC2C1
c1cn2nc[nH]c2n1
123.119
31.7501
-0.3604
4
2
40,970
3.48344
1.27884
1.15542
1.3904
70.39
-0.252
0.0653
0.3174
1,105.8006
0.160828
-460.139231
-460.131548
-460.130604
-460.171695
29.593
C1OCC11CCOCO1
C1CC2(COC2)OCO1
false
C1CCC2(CC1)CCC2
C1CC2(COC2)OCO1
130.143
30.071
0.1498
3
0
27,342
3.27227
1.37707
0.9692
6.0742
64.42
-0.2329
-0.0268
0.2061
1,097.8135
0.0891
-493.740775
-493.733226
-493.732282
-493.77268
28.72
OC1=CC(=O)C(O)=CO1
O=c1cc(O)occ1O
false
CC1CCC(C)C(C)C1
O=c1ccocc1
128.083
28.3076
0.051
4
2
123,900
3.47224
1.54878
1.11468
4.4485
74.54
-0.2011
0.0156
0.2167
1,053.5609
0.13968
-418.017166
-418.010055
-418.009111
-418.048623
27.959
C1CNC2=C(C1)C=NO2
c1noc2c1CCCN2
false
C1CCC2CCCC2C1
c1noc2c1CCCN2
124.143
33.3137
1.0327
3
1
61,251
3.45574
0.84628
0.77796
4.2814
80.43
-0.2413
0.0357
0.277
1,508.6197
0.1703
-399.300464
-399.290452
-399.289508
-399.335906
36.097
CN1CC1C(N)CC#N
CN1CC1C(N)CC#N
true
CCCC(C)C1CC1C
C1CN1
125.175
34.6234
-0.45862
3
1
104,204
2.4957
1.25318
1.18047
1.251
85.45
-0.2603
0.0743
0.3346
1,223.5938
0.204574
-388.264881
-388.255118
-388.254173
-388.299
37.688
CC1(CO)CCC11CC1
CC1(CO)CCC12CC2
false
CCC1(C)CCC12CC2
C1CC2(C1)CC2
126.199
36.0938
1.559
1
1
67,933
2.2347
1.50728
1.06025
4.2335
67.43
-0.2595
-0.0444
0.2152
1,122.5184
0.110298
-457.772175
-457.76395
-457.763006
-457.805357
29.827
CC12OC(=O)C1C2C=O
CC12OC(=O)C1C2C=O
true
CCC1C2C(C)CC12C
O=C1OC2CC12
126.111
27.541
-0.2532
3
0
23,532
2.02944
1.78628
1.07411
1.1846
78.92
-0.2359
0.0077
0.2436
1,110.1107
0.122607
-400.636338
-400.628001
-400.627057
-400.669248
31.851
ON=C1C2CC2C1C#C
C#CC1C(=NO)C2CC12
false
CCC1C(CC)C2CC12
N=C1CC2CC12
121.139
33.1415
0.7157
2
1
68,493
3.07648
1.3159
1.12373
2.5384
79.75
-0.2397
0.0062
0.2459
1,114.8349
0.134136
-384.628742
-384.620264
-384.61932
-384.66159
32.294
CC12CC(C1C#C)C2=O
C#CC1C2CC1(C)C2=O
false
CCC1C2CC1(C)C2C
O=C1C2CC1C2
120.151
33.544
0.8447
1
0
75,892
2.36433
1.47324
1.22031
3.0494
82.61
-0.253
0.031
0.284
1,160.7686
0.194094
-404.384947
-404.375504
-404.37456
-404.418517
36.526
CC1C(=N)OCC1(C)C
CC1C(=N)OCC1(C)C
true
CC1CCC(C)(C)C1C
N=C1CCCO1
127.187
36.6237
1.65617
2
1
119,444
4.66268
0.89882
0.8546
3.4275
75.4
-0.2588
0.0213
0.2801
1,398.0038
0.146343
-439.041853
-439.03304
-439.032095
-439.076154
31.973
COCC12CC1C(=N)O2
COCC12CC1C(=N)O2
true
CCCC12CC(C)C1C2
N=C1OC2CC12
127.143
31.5257
0.39897
3
1
27,986
2.4691
1.39705
0.89818
3.388
81.88
-0.1927
-0.0249
0.1678
1,252.6991
0.136709
-418.066743
-418.058099
-418.057155
-418.099757
32.459
CC1=CC(N)=CN1C=O
Cc1cc(N)cn1C=O
false
CCC1CC(C)CC1C
c1cc[nH]c1
124.143
35.7299
0.41702
3
1
122,367
5.02562
0.70989
0.69711
2.6775
80.44
-0.2353
0.0822
0.3175
1,709.0993
0.181313
-424.141308
-424.132189
-424.131244
-424.176528
33.362
CCOCC1C2CC1O2
CCOCC1C2CC1O2
true
CCCCC1C2CC1C2
C1C2CC1O2
128.171
33.261
0.8102
2
0
74,262
2.611
1.40182
1.12439
3.3332
74.84
-0.222
-0.0095
0.2125
1,151.14
0.145991
-439.139517
-439.130246
-439.129302
-439.173043
34.891
CC1=CC(C)(O)C(=O)N1
CC1=CC(C)(O)C(=O)N1
true
CC1CC(C)C(C)(C)C1
O=C1CC=CN1
127.143
32.5235
-0.229
2
2
40,873
4.06101
1.43285
1.31585
2.5702
70.14
-0.2381
0.0716
0.3097
978.82
0.136511
-421.722782
-421.715969
-421.715025
-421.754284
26.921
C1OCC11C2C3OC1C23
C1OCC12C1OC3C1C32
false
C1CC2(C1)C1CC3C1C32
C1OCC12C1OC3C1C32
124.139
28.893
0.03
2
0
31,530
3.10142
1.05918
0.8409
1.2497
89.4
-0.1724
0.0553
0.2277
1,452.4794
0.182201
-383.310373
-383.299946
-383.299002
-383.346594
37.115
CNC1=CC(C)=C(C)N1
CNc1cc(C)c(C)[nH]1
false
CCC1CC(C)C(C)C1
c1cc[nH]c1
124.187
39.8134
1.67324
1
2
61,079
3.60529
1.07615
0.89704
1.7665
65.16
-0.2643
-0.0397
0.2246
1,257.4929
0.135139
-496.099257
-496.090708
-496.089763
-496.133341
30.492
OC(C=O)C1COCO1
O=CC(O)C1COCO1
false
CCC(C)C1CCCC1
C1COCO1
132.115
27.7628
-1.0809
4
1
82,904
2.95729
1.81796
1.57079
1.2943
80.05
-0.2541
0.0771
0.3313
942.4634
0.188173
-387.08518
-387.078713
-387.077769
-387.115509
28.84
OC1C2CC3CC2CC13
OC1C2CC3CC2CC31
false
CC1C2CC3CC2CC31
C1C2CC3CC2CC13
124.183
33.8178
1.0232
1
1
95,106
2.59069
1.65306
1.19835
4.3267
79.82
-0.2195
0.026
0.2456
1,070.663
0.16087
-382.066147
-382.057959
-382.057015
-382.098665
31.804
CN1CCC2CC12C#N
CN1CCC2CC21C#N
false
CCC12CC1CCC2C
C1CC2CC2N1
122.171
33.698
0.60418
2
0
81,524
3.80768
1.28865
1.07785
2.1921
68.03
-0.2558
0.0201
0.2759
1,079.0759
0.10971
-457.641851
-457.63371
-457.632765
-457.674121
31.69
OC1C2OC1C2(O)C#C
C#CC1(O)C2OC1C2O
false
CCC1(C)C2CC1C2C
C1C2CC1O2
126.111
28.4506
-1.5074
3
2
130,327
3.21265
1.28809
0.99582
4.3464
68.65
-0.2466
-0.0319
0.2147
1,129.2144
0.100388
-432.794823
-432.786747
-432.785803
-432.827739
30.005
NC1=NON=C1CC#C
C#CCc1nonc1N
false
CCCC1CCCC1C
c1cnon1
123.115
31.2474
-0.1725
4
1
70,260
2.85883
1.43818
1.18102
3.8337
75.3
-0.2598
0.0178
0.2776
1,089.2191
0.147778
-401.955111
-401.946862
-401.945918
-401.988083
31.378
CC12CC1CC(O2)C#N
CC12CC1CC(C#N)O2
false
CCC1CC2CC2(C)C1
C1CC2CC2O1
123.155
31.615
1.07748
2
0
100,429
2.81705
0.79445
0.68478
0.7388
89.6
-0.2428
0.0322
0.275
1,778.235
0.213897
-405.567484
-405.555735
-405.554791
-405.606431
41.166
COC(C)=NCC(C)C
COC(C)=NCC(C)C
true
CCC(C)CCC(C)C
129.203
39.823
1.7072
2
0
64,537
4.07832
1.2509
1.1108
3.6614
72.36
-0.2452
-0.027
0.2183
1,086.8514
0.133914
-421.746874
-421.738978
-421.738034
-421.779192
30.443
CC1(C=O)C2C3OC3C12
CC1(C=O)C2C3OC3C21
false
CCC1(C)C2C3CC3C21
C1C2C1C1OC21
124.139
29.812
0.2186
2
0
66,760
2.82545
2.15131
1.54738
3.8513
68.81
-0.2347
0.003
0.2377
849.3757
0.113425
-416.699326
-416.692767
-416.691823
-416.729959
26.831
OC12C3C4C3N(C14)C2=N
N=C1N2C3C4C3C1(O)C42
false
CC1C2C3C4C3C1(C)C24
N=C1C2C3C4C2N1C34
122.127
29.0715
-0.97923
2
2
38,744
2.42821
2.18643
1.78052
0.2908
85.06
-0.2284
0.0253
0.2537
907.729
0.187991
-349.973159
-349.966818
-349.965874
-350.003282
28.313
C1C2CC3CC2C1C=C3
C1=CC2CC3CC1CC23
false
C1CC2CC3CC1CC23
C1=CC2CC3CC1CC23
120.195
36.951
2.2185
0
0
62,880
2.83408
1.57831
1.15938
2.7007
72.02
-0.2498
0.0572
0.307
1,084.4508
0.15613
-460.091976
-460.083025
-460.082081
-460.124713
35.415
CC1(O)C2OC1C2(C)O
CC1(O)C2OC1C2(C)O
true
CC1(C)C2CC1C2(C)C
C1C2CC1O2
130.143
29.9086
-0.7306
3
2
76,208
2.29263
1.3492
1.25023
1.8752
74.88
-0.2456
0.0631
0.3087
1,162.7979
0.178268
-461.352086
-461.341582
-461.340638
-461.38625
40.168
CC1(O)CC(C)(O)C1O
CC1(O)CC(C)(O)C1O
true
CC1C(C)(C)CC1(C)C
C1CCC1
132.159
31.8714
-0.747
3
3
76,477
3.11542
1.05066
0.99525
4.0641
76.88
-0.2393
-0.0174
0.222
1,274.9067
0.156519
-423.016248
-423.006988
-423.006044
-423.050513
34.596
CC1C(O)C11CC(=O)C1
CC1C(O)C12CC(=O)C2
false
CC1CC2(C1)C(C)C2C
O=C1CC2(CC2)C1
126.155
31.8448
0.3463
2
1
27,600
3.4167
1.20206
0.88922
0.8274
86.52
-0.2228
-0.0292
0.1936
1,227.4571
0.113364
-383.530312
-383.522691
-383.521747
-383.562198
30.05
OC1=CC(=CC=C1)C#C
C#Cc1cccc(O)c1
false
CCC1CCCC(C)C1
c1ccccc1
118.135
36.0418
1.3735
1
1