index
int64
1
134k
A
float64
0
620k
B
float64
0.34
438
C
float64
0.33
283
mu
float64
0
29.6
alpha
float64
6.31
197
homo
float64
-0.43
-0.1
lumo
float64
-0.18
0.19
gap
float64
0.02
0.62
r2
float64
19
3.37k
zpve
float64
0.02
0.27
U0
float64
-714.57
-40.48
U
float64
-714.56
-40.48
H
float64
-714.56
-40.48
G
float64
-714.6
-40.5
Cv
float64
6
47
smiles
stringlengths
1
28
canonsmiles
stringlengths
1
34
isSmilesEqual
bool
2 classes
generic_scaffold
stringlengths
1
21
scaffold
stringlengths
0
31
rdkit_WT
float64
16
152
rdkit_MR
float64
3.61
43.7
rdkit_LogP
float64
-4.91
3.76
rdkit_HA
float64
0
7
rdkit_HD
float64
0
5
14,536
4.48322
1.60933
1.44782
5.2134
69.37
-0.2546
0.0238
0.2784
895.4967
0.130967
-342.749509
-342.742147
-342.741203
-342.780832
27.805
CC1(C#N)C2CCN12
CC1(C#N)C2CCN21
false
CCC1(C)C2CCC21
C1CN2CC12
108.144
29.129
0.35658
2
0
107,715
3.36431
1.28561
1.1126
2.3482
76.21
-0.2522
0.0718
0.324
1,132.6221
0.158472
-422.94388
-422.935485
-422.934541
-422.976656
32.689
OCC12CC3(O)C1CC23
OCC12CC3(O)C1CC32
false
CCC12CC3(C)C1CC32
C1C2C3CC2C13
126.155
30.6826
-0.2504
2
2
65,994
2.24281
1.50921
1.37512
1.0062
75.07
-0.2536
-0.0315
0.2221
1,078.7588
0.157001
-423.01298
-423.003942
-423.002997
-423.046897
33.471
CC1(OCC1=O)C1CC1
CC1(C2CC2)OCC1=O
false
CC1CCC1(C)C1CC1
O=C1COC1C1CC1
126.155
32.088
0.7544
2
0
31,427
3.06487
1.44274
0.98706
1.0271
72.12
-0.2303
-0.0404
0.1899
1,134.4284
0.115589
-450.177624
-450.169981
-450.169037
-450.210052
28.074
COC1=NC(=N)NC=N1
COc1nc[nH]c(=N)n1
false
CCC1CCCC(C)C1
N=c1ncnc[nH]1
126.119
28.7894
-0.70723
4
2
114,164
5.16977
0.90597
0.83834
4.6392
71.08
-0.2785
-0.0043
0.2742
1,329.3954
0.123298
-437.84732
-437.838845
-437.837901
-437.880822
30.805
OCC1CC2(OC12)C#N
N#CC12CC(CO)C1O2
false
CCC1CC2(CC)CC12
C1CC2OC12
125.127
28.4098
-0.34022
3
1
16,632
3.23797
2.24107
1.4917
3.5675
68.74
-0.2274
0.0317
0.2591
859.5647
0.143697
-363.896429
-363.88917
-363.888226
-363.927873
27.474
CN1C2CC2CC1=O
CN1C(=O)CC2CC21
false
CC1CC2CC2C1C
O=C1CC2CC2N1
111.144
29.282
0.237
1
0
58,094
2.16422
1.30735
1.17645
2.4559
77.9
-0.2384
0.0348
0.2732
1,217.2829
0.190781
-441.527101
-441.515641
-441.514697
-441.563615
41.936
CC(O)C(C)(C)C(N)=O
CC(O)C(C)(C)C(N)=O
true
CC(C)C(C)(C)C(C)C
131.175
34.6562
-0.1213
2
2
2,623
15.76239
0.86651
0.84311
2.2464
59.31
-0.2734
-0.0722
0.2012
1,229.3295
0.074984
-343.235457
-343.227698
-343.226754
-343.269283
24.12
O=CCC#CC=O
O=CC#CCC=O
false
CCCCCCC
96.085
24.521
-0.2223
2
0
28,536
3.26784
1.43339
0.99667
3.3153
68.67
-0.2079
-0.0132
0.1947
1,090.279
0.102924
-470.079511
-470.07177
-470.070826
-470.111359
29.904
NC1=NC(O)=NC=C1O
Nc1nc(O)ncc1O
false
CC1CCC(C)C(C)C1
c1cncnc1
127.103
29.774
-0.53
5
3
98,738
2.97837
0.94945
0.84719
5.0702
76.22
-0.2371
-0.0185
0.2187
1,419.571
0.146346
-439.117648
-439.107966
-439.107021
-439.153332
33.782
CNC(=O)C1CC1C=O
CNC(=O)C1CC1C=O
true
CCC(C)C1CC1CC
C1CC1
127.143
31.7277
-0.4326
2
1
33,330
3.20278
0.87388
0.71599
3.3705
82.49
-0.2639
-0.0513
0.2125
1,467.06
0.075019
-398.270029
-398.261592
-398.260648
-398.303966
29.759
C#CC#CC1OC1C#N
C#CC#CC1OC1C#N
true
CCCCC1CC1CC
C1CO1
117.107
30.883
-0.08602
2
0
42,252
2.89905
1.1351
1.01556
3.7029
73.17
-0.2693
-0.0748
0.1945
1,180.4743
0.084897
-419.331589
-419.322804
-419.32186
-419.365909
31.114
O=C(C#C)C1OC1C#C
C#CC(=O)C1OC1C#C
false
CCC(C)C1CC1CC
C1CO1
120.107
31.334
-0.4107
2
0
125,449
7.06866
0.83092
0.75559
2.5854
74.91
-0.2303
-0.0164
0.2139
1,458.4684
0.112701
-450.148323
-450.139597
-450.138653
-450.182433
30.377
CC1=NC(N=CN)=NO1
Cc1nc(N=CN)no1
false
CCCC1CCC(C)C1
c1ncon1
126.119
31.3744
-0.00348
4
1
7,812
3.22414
1.74906
1.22008
2.9537
64.67
-0.2184
-0.0181
0.2004
966.0194
0.143446
-401.013582
-401.00596
-401.005016
-401.045533
28.867
OC1CNCC(=O)C1
O=C1CNCC(O)C1
false
CC1CCCC(C)C1
O=C1CCCNC1
115.132
28.5005
-1.0903
3
2
13,472
3.43891
1.95145
1.26772
0.5572
65.4
-0.2354
-0.0047
0.2306
913.7218
0.12033
-396.02195
-396.014377
-396.013433
-396.053913
27.959
NC(=N)N1CCC1=O
N=C(N)N1CCC1=O
false
CC(C)C1CCC1C
O=C1CCN1
113.12
28.2441
-0.88783
2
2
112,229
2.02758
1.51952
0.98509
6.1799
71.25
-0.2687
-0.046
0.2227
1,196.8365
0.122066
-437.887609
-437.878646
-437.877702
-437.922143
31.494
COC1CC(=O)C1C#N
COC1CC(=O)C1C#N
true
CCC1CC(C)C1CC
O=C1CCC1
125.127
29.524
0.11398
3
0
85,653
2.14183
1.72594
1.20261
4.0824
61.92
-0.3014
-0.0296
0.2718
1,029.3471
0.100219
-473.867917
-473.859859
-473.858914
-473.901276
28.564
CC1OC(C#N)C(=O)O1
CC1OC(=O)C(C#N)O1
false
CCC1CC(C)CC1C
O=C1COCO1
127.099
26.04
-0.20202
4
0
79,243
2.38662
1.63325
1.39912
1.6992
74.74
-0.2262
0.0626
0.2888
1,032.9049
0.157791
-422.968023
-422.959312
-422.958368
-423.000727
33.991
CC1C2C3CC1(O)C23O
CC1C2C3CC1(O)C32O
false
CC1C2C3CC1(C)C32C
C1C2CC3C1C23
126.155
30.6606
-0.252
2
2
72,011
2.53627
1.98573
1.46483
3.4007
71.66
-0.2258
-0.0169
0.2089
929.3084
0.13639
-421.796564
-421.789453
-421.788509
-421.827866
28.549
CC12CC3OC1C(=O)C23
CC12CC3OC1C(=O)C32
false
CC1C2CC3CC2(C)C31
O=C1C2OC3CC2C13
124.139
29.882
0.3627
2
0
39,642
4.42566
0.93395
0.87856
2.0647
78.45
-0.2319
0.0097
0.2416
1,354.2191
0.160136
-422.999013
-422.990663
-422.989719
-423.033514
29.846
C1OCC1C1=CCOC1
C1=C(C2COC2)COC1
false
C1CCC(C2CCC2)C1
C1=C(C2COC2)COC1
126.155
33.211
0.5894
2
0
49,128
2.81983
1.37727
0.92532
1.1445
66.63
-0.2821
-0.1297
0.1524
1,131.8022
0.077411
-472.683341
-472.675989
-472.675045
-472.715723
26.167
N=C1OC(=O)C=C1C=O
N=C1OC(=O)C=C1C=O
true
CCC1CC(C)CC1C
N=C1C=CC(=O)O1
125.083
27.9657
-0.35423
4
1
80,993
2.66455
1.52137
1.20244
4.0256
79.2
-0.235
0.0253
0.2603
1,106.324
0.17159
-403.171335
-403.162963
-403.162019
-403.203614
33.372
CC1C2CC1(C)NC2=O
CC1C2CC1(C)NC2=O
true
CC1CC2(C)CC1C2C
O=C1NC2CC1C2
125.171
33.8187
0.5309
1
1
97,238
2.9856
1.44579
1.01231
4.2526
74.3
-0.2303
-0.0448
0.1855
1,154.6981
0.136948
-455.17611
-455.167654
-455.16671
-455.209625
30.911
CN=C1NCCOC1=O
CN=C1NCCOC1=O
true
CCC1CCCCC1C
N=C1NCCOC1=O
128.131
32.3207
-0.8389
3
1
52,638
2.69675
0.68756
0.56454
4.2094
89.76
-0.2668
-0.046
0.2208
1,881.6917
0.110973
-379.619413
-379.609195
-379.608251
-379.657095
34.122
CC#CC(N)C#CC#N
CC#CC(N)C#CC#N
true
CCCCC(C)CCC
118.139
34.8144
-0.13602
2
1
991
3.92426
3.15025
1.75905
1.2377
59.91
-0.1708
0.064
0.2348
684.8792
0.115587
-320.776316
-320.769025
-320.768081
-320.807481
26.767
NC1=CNC=C1N
Nc1c[nH]cc1N
false
CC1CCCC1C
c1cc[nH]c1
97.121
29.6175
0.1791
2
3
71,529
2.59736
1.57452
1.44089
3.2319
70.62
-0.2601
-0.0191
0.241
968.4238
0.111832
-416.705533
-416.698018
-416.697074
-416.737464
28.673
CC12NC3C1OC23C#N
CC12NC3C1OC32C#N
false
CCC12CC3C1CC32C
N1C2C3OC2C13
122.127
28.5457
-0.60832
3
1
115,386
3.22195
1.07377
0.95803
1.5032
82.03
-0.2541
0.0844
0.3385
1,373.3287
0.206055
-425.446124
-425.436672
-425.435728
-425.480255
35.868
CCC1OCC(C)CO1
CCC1OCC(C)CO1
true
CCC1CCC(C)CC1
C1COCOC1
130.187
35.147
1.4054
2
0
70,849
3.09089
1.7924
1.43597
1.9029
70.41
-0.2212
0.0717
0.2929
917.4922
0.135648
-421.744426
-421.737345
-421.736401
-421.775217
29.904
OC12CC3(O)C4C(C14)C23
OC12CC3(O)C4C(C41)C23
false
CC12CC3(C)C4C(C41)C23
C1C2C3C1C1C2C31
124.139
28.4766
-0.6421
2
2
99,597
2.22683
1.23042
0.9979
3.4883
75.41
-0.2606
0.0259
0.2865
1,268.2727
0.158445
-419.192259
-419.182493
-419.181549
-419.227189
35.412
CC1(CN1)C(CO)C#N
CC1(C(C#N)CO)CN1
false
CCC(CC)C1(C)CC1
C1CN1
126.159
32.5965
-0.51962
3
2
72,728
2.66914
1.9685
1.55149
0.3135
75.23
-0.245
0.0316
0.2767
932.3781
0.158659
-422.892545
-422.885032
-422.884088
-422.923843
31.027
CC12OCC11CCC2O1
CC12OCC13CCC2O3
false
CC12CCC13CCC2C3
C1CC23COC2C1O3
126.155
31.195
0.7067
2
0
103,156
1.91998
1.58617
1.17733
2.4361
71.73
-0.244
-0.0323
0.2117
1,148.6068
0.155653
-460.165581
-460.155493
-460.154549
-460.200368
36.739
CCC1(O)C(O)CC1=O
CCC1(O)C(=O)CC1O
false
CCC1(C)C(C)CC1C
O=C1CCC1
130.143
30.8716
-0.5388
3
2
87,061
2.26957
1.48342
1.15397
2.5867
77.12
-0.2499
0.0086
0.2585
1,132.3784
0.147705
-398.08116
-398.072299
-398.071355
-398.114775
32.546
CN1CC1(C#N)C1CN1
CN1CC1(C#N)C1CN1
true
CCC1(C2CC2)CC1C
C1NC1C1CN1
123.159
32.7647
-0.83402
3
1
85,652
2.09369
1.76338
1.21036
4.119
66.61
-0.2898
-0.0125
0.2774
1,041.6137
0.112412
-453.967952
-453.959753
-453.958809
-454.001331
29.526
CC1OC(C#N)C(=N)O1
CC1OC(=N)C(C#N)O1
false
CCC1CC(C)CC1C
N=C1COCO1
126.115
28.7597
0.24865
4
1
7,382
3.37697
1.35845
1.02682
4.2292
61.74
-0.2581
0.0228
0.281
1,128.6775
0.140996
-438.160511
-438.151487
-438.150543
-438.194463
32.139
COCC(O)C(N)=O
COCC(O)C(N)=O
true
CCCC(C)C(C)C
119.12
27.0772
-1.521
3
2
12,237
3.30895
1.55981
1.18176
3.0118
60.68
-0.2752
0.0038
0.279
1,006.2062
0.129834
-420.902044
-420.893898
-420.892954
-420.934955
29.073
CC1C(CO)OC1=O
CC1C(=O)OC1CO
false
CCC1CC(C)C1C
O=C1CCO1
116.116
26.1298
-0.4598
3
1
119,608
4.04751
0.92838
0.85301
1.0669
78.31
-0.2263
0.0875
0.3139
1,445.1206
0.182059
-424.209513
-424.200502
-424.199558
-424.243644
33.77
CCCC12CC1OCO2
CCCC12CC1OCO2
true
CCCC12CCCC1C2
C1OC2CC2O1
128.171
33.081
1.3019
2
0
92,720
2.28658
1.61369
1.05203
2.9866
79.29
-0.2391
-0.0138
0.2253
1,169.222
0.159416
-419.263491
-419.254467
-419.253523
-419.29738
32.981
CC1CN=C(C)N1C=O
CC1=NCC(C)N1C=O
false
CCC1C(C)CCC1C
C1=NCCN1
126.159
35.341
0.2653
2
0
54,093
2.72212
1.43271
1.29503
2.1728
75.26
-0.2376
-0.0189
0.2187
1,075.8422
0.156415
-422.972407
-422.963447
-422.962502
-423.006356
33.472
CC(=O)C1(C)C2CC1O2
CC(=O)C1(C)C2CC1O2
true
CC(C)C1(C)C2CC1C2
C1C2CC1O2
126.155
32.066
0.7528
2
0
36,187
3.83594
1.1193
1.10554
4.1771
79.22
-0.2618
0.0355
0.2973
1,160.3141
0.14908
-364.778719
-364.771205
-364.77026
-364.811224
29.303
N#CCC12CC3CC1C23
N#CCC12CC3CC1C32
false
CCCC12CC3CC1C32
C1C2CC3C1C23
119.167
32.367
1.55608
1
0
63,601
4.33971
0.66638
0.64079
4.766
92.96
-0.2571
-0.0537
0.2034
1,783.0844
0.156278
-385.869185
-385.859081
-385.858136
-385.904956
35.835
CC1(C)CC1C#CC=O
CC1(C)CC1C#CC=O
true
CCCCC1CC1(C)C
C1CC1
122.167
35.728
1.2348
1
0
18,084
5.00598
1.1402
1.11429
2.0313
71.84
-0.228
0.0776
0.3055
1,155.6346
0.165702
-364.99413
-364.986023
-364.985079
-365.027409
29.472
COCC1C2CCN12
COCC1C2CCN21
false
CCCC1C2CCC12
C1CN2CC12
113.16
30.775
0.0893
2
0
68,312
3.19149
1.31831
1.16772
1.4868
72.4
-0.2459
0.0667
0.3126
1,100.6854
0.147817
-438.973098
-438.96523
-438.964286
-439.005742
30.399
OC12CN(C1)C2C1CO1
OC12CN(C1)C2C1CO1
true
CC12CC(C1)C2C1CC1
C1OC1C1C2CN1C2
127.143
30.0508
-1.1859
3
1
118,113
3.45458
0.73596
0.66482
0.342
82.69
-0.2555
0.0731
0.3286
1,762.7923
0.20351
-425.407314
-425.396237
-425.395293
-425.444128
39.783
CC1CC1C(O)CCO
CC1CC1C(O)CCO
true
CCCC(C)C1CC1C
C1CC1
130.187
34.9806
0.3857
2
2
26,167
2.55748
1.31956
1.06016
0.8036
82.78
-0.2097
0.0248
0.2345
1,234.3691
0.169939
-403.166592
-403.157079
-403.156135
-403.201566
34.705
CN(C)C1=C(C)OC=C1
Cc1occc1N(C)C
false
CC(C)C1CCCC1C
c1ccoc1
125.171
37.772
1.65402
2
0
31,969
2.91094
1.11167
0.8495
2.8228
78.16
-0.1807
0.0277
0.2084
1,361.2866
0.14755
-439.100318
-439.090955
-439.090011
-439.135499
33.397
CNC1=CC=C(CO)O1
CNc1ccc(CO)o1
false
CCC1CCC(CC)C1
c1ccoc1
127.143
34.1775
0.8136
3
2
62,175
6.10982
0.60797
0.57627
1.7023
67.67
-0.2571
-0.0317
0.2253
1,808.4469
0.132144
-496.121937
-496.1118
-496.110856
-496.159264
33.784
OC(COC=O)CC=O
O=CCC(O)COC=O
false
CCCCC(C)CCC
132.115
28.7038
-0.8907
4
1
111,476
2.65182
1.61287
1.1243
2.1703
73.18
-0.2466
0.0133
0.26
1,096.0946
0.148018
-439.070714
-439.062545
-439.061601
-439.10381
30.771
COC1C2CC2OC1=N
COC1C(=N)OC2CC21
false
CCC1C(C)CC2CC21
N=C1CC2CC2O1
127.143
31.5037
0.39737
3
1
38,483
3.39455
1.72129
1.59398
1.2735
69.64
-0.2249
0.054
0.2789
885.0257
0.137448
-421.751609
-421.745153
-421.744208
-421.782033
27.021
C1C23CC4OC4C12CO3
C1C2OC2C23COC12C3
false
C1C2CC34CCC3(C4)C12
C1C2OC2C23COC12C3
124.139
29.011
0.3166
2
0
68,419
2.61294
1.87032
1.43015
2.0172
70.85
-0.2275
0.0594
0.2869
950.3558
0.148566
-439.019336
-439.011952
-439.011007
-439.050737
30.039
OC12CN(C1)CC21CO1
OC12CN(C1)CC21CO1
true
CC12CC(C1)CC21CC1
C1C2CN1CC21CO1
127.143
30.0728
-1.1843
3
1
100,592
2.19545
1.08276
0.79046
1.3781
74.01
-0.2633
-0.0558
0.2075
1,452.3403
0.155411
-460.19164
-460.18126
-460.180316
-460.228486
36.039
CCC(O)C(=O)CC=O
CCC(O)C(=O)CC=O
true
CCCC(C)C(C)CC
130.143
31.9858
-0.0846
3
1
79,472
2.55822
1.87395
1.48916
1.1663
66.21
-0.2263
0.0695
0.2958
918.7759
0.136657
-458.91012
-458.90295
-458.902006
-458.941215
29.457
OC1C2C3CC1(O)C2O3
OC1C2C3CC1(O)C2O3
true
CC1C2C3CC2C1(C)C3
C1C2CC3C1OC23
128.127
27.7246
-1.1207
3
2
90,993
2.73245
1.91242
1.38398
2.3899
71.24
-0.2256
0.0589
0.2845
948.2888
0.148774
-439.018857
-439.011469
-439.010524
-439.050234
30.211
OC1CN2C3CC2C13O
OC1CN2C3CC2C13O
true
CC1CC2C3CC2C13C
C1CN2C3CC2C13
127.143
29.8556
-1.4515
3
2
38,882
2.82391
2.20208
1.94871
1.9012
64.72
-0.2429
0.0817
0.3246
795.5393
0.140534
-458.953197
-458.947638
-458.946693
-458.982816
24.451
C1C2OC3OC2COC13
C1OC2CC3OC2OC13
false
C1CC2CC3CC2CC13
C1OC2CC3OC2OC13
128.127
27.891
-0.101
3
0
25,305
3.28994
1.40706
0.98555
1.5382
66.93
-0.254
-0.1149
0.1391
1,088.301
0.089857
-452.797474
-452.790057
-452.789113
-452.830238
26.204
O=CC(=O)N1C=CN=C1
O=CC(=O)n1ccnc1
false
CCC(C)C1CCCC1
c1c[nH]cn1
124.099
28.9175
-0.2778
4
0
92,494
2.46432
1.51488
1.32617
1.4013
84.27
-0.2359
0.0789
0.3148
1,130.002
0.206287
-388.29986
-388.290973
-388.290029
-388.333031
35.156
CC1CC2(C)CCC2O1
CC1CC2(C)CCC2O1
true
CC1CC2CCC2(C)C1
C1CC2CCC2O1
126.199
36.293
1.9639
1
0
79,171
2.88146
1.91724
1.41384
4.7381
71.71
-0.222
0.0279
0.2498
933.9726
0.137877
-417.986021
-417.978767
-417.977822
-418.017806
27.972
CN1C2C3CN(C23)C1=O
CN1C(=O)N2CC3C1C32
false
CC1C(C)C2C3CC1C32
O=C1NC2C3CN1C32
124.143
30.931
-0.2656
1
0
5,148
6.36414
1.32287
1.10256
0.961
63.44
-0.2452
0.0017
0.2469
994.4071
0.09571
-361.457954
-361.451
-361.450056
-361.48972
25.207
C#CCC1=COC=N1
C#CCc1cocn1
false
CCCC1CCCC1
c1cocn1
107.112
29.04
0.8503
2
0
91,905
2.36608
1.57648
1.04362
1.2984
85.74
-0.2263
0.019
0.2453
1,215.3513
0.182249
-387.090973
-387.0822
-387.081256
-387.124079
34.183
CC1OC2CC2C(C)=C1
CC1=CC(C)OC2CC12
false
CC1CC(C)C2CC2C1
C1=CC2CC2OC1
124.183
36.199
1.7399
1
0
94,381
2.99948
1.38733
1.26704
1.9363
74.81
-0.2478
0.0747
0.3226
1,071.5556
0.158577
-422.96558
-422.957456
-422.956512
-422.998296
31.653
OC1CCC11CC2OC12
OC1CCC12CC1OC12
false
CC1CCC12CC1CC12
C1CC2(C1)CC1OC12
126.155
30.9518
0.2986
2
1
121,306
3.21452
0.93279
0.76456
2.6211
86.2
-0.2323
-0.0134
0.2189
1,576.8622
0.205822
-388.339907
-388.330218
-388.329274
-388.375136
36.002
CCCC1CCCC1=O
CCCC1CCCC1=O
true
CCCC1CCCC1C
O=C1CCCC1
126.199
37.256
2.1557
1
0
8,757
4.33505
1.45126
1.09481
1.5936
58.68
-0.2937
-0.0953
0.1984
974.8437
0.082537
-414.708012
-414.69991
-414.698966
-414.741154
26.826
CN(C=O)C(=O)C#N
CN(C=O)C(=O)C#N
true
CCC(C)C(C)CC
112.088
24.447
-0.87522
3
0
41,424
3.33758
1.94944
1.54892
1.9758
69.95
-0.2398
0.0689
0.3088
868.5233
0.138397
-421.758239
-421.752098
-421.751154
-421.788427
25.916
C1OC2C3C4COC12C34
C1OC23COC2C2C1C23
false
C1CC23CCC2C2C1C23
C1OC23COC2C2C1C23
124.139
28.893
0.03
2
0
13,608
4.61393
1.32206
1.17825
2.5381
62.96
-0.2446
0.0026
0.2472
1,040.0606
0.129528
-420.895193
-420.887047
-420.886102
-420.928081
29.334
COC(=O)C1CC1O
COC(=O)C1CC1O
true
CCC(C)C1CC1C
C1CC1
116.116
26.1298
-0.4598
3
1
10,540
3.01542
1.3992
1.07414
3.7526
69.19
-0.2978
0.0042
0.3019
1,132.8643
0.140692
-363.858638
-363.850001
-363.849056
-363.892261
30.605
CCCC1(CO1)C#N
CCCC1(C#N)CO1
false
CCCC1(CC)CC1
C1CO1
111.144
29.204
1.07908
2
0
22,358
2.74798
1.12352
0.9353
0.9801
77.75
-0.2424
0.0073
0.2497
1,304.1369
0.170092
-440.261535
-440.252199
-440.251255
-440.295517
35.61
CC1CC(CC1O)=NO
CC1CC(=NO)CC1O
false
CCC1CC(C)C(C)C1
N=C1CCCC1
129.159
33.6263
0.6074
3
2
53,210
3.26619
0.87942
0.77791
4.0491
83.61
-0.2416
0.0315
0.2731
1,521.3417
0.145791
-401.95079
-401.940728
-401.939784
-401.98776
34.122
CC#CC1CC(=O)N1C
CC#CC1CC(=O)N1C
true
CCCC1CC(C)C1C
O=C1CCN1
123.155
34.625
0.2404
1
0
51,554
2.42424
1.45433
1.09353
3.3024
80.22
-0.2451
0.0259
0.271
1,170.5078
0.171217
-403.148274
-403.139426
-403.138482
-403.182283
33.087
O=CNC1CC11CCC1
O=CNC1CC12CCC2
false
CCCC1CC12CCC2
C1CC2(C1)CC2
125.171
33.8887
0.675
1
1
115,629
2.15907
1.38677
1.01015
1.0201
87.28
-0.2406
0.0818
0.3224
1,311.5929
0.204546
-388.261816
-388.251986
-388.251041
-388.296527
36.775
COC1CCC11CC1C
COC1CCC12CC2C
false
CCC1CCC12CC2C
C1CC2(C1)CC2
126.199
36.245
1.8214
1
0
22,740
2.58195
1.38393
0.99664
1.2903
69.77
-0.2574
-0.029
0.2283
1,160.9565
0.121901
-474.931758
-474.923089
-474.922145
-474.965425
32.054
ON=C1C(O)CC11CO1
ON=C1C(O)CC12CO2
false
CCC1C(C)CC12CC2
N=C1CCC12CO2
129.115
28.5283
-0.6498
4
2
115,070
3.02159
1.24796
0.97915
1.5848
83.33
-0.2208
0.0264
0.2472
1,245.7521
0.184274
-387.08775
-387.07928
-387.078336
-387.120743
33.24
OCC1CC=CC2CC12
OCC1CC=CC2CC21
false
CCC1CCCC2CC12
C1=CC2CC2CC1
124.183
35.9298
1.1909
1
1
105,164
2.72424
1.13403
0.97202
2.7606
77.42
-0.2588
-0.04
0.2188
1,244.0842
0.133388
-421.786762
-421.777515
-421.776571
-421.82084
34.038
OCC1(CC1C#C)C=O
C#CC1CC1(C=O)CO
false
CCC1CC1(CC)CC
C1CC1
124.139
32.5228
-0.1829
2
1
1,726
4.44585
2.08002
1.8923
2.1778
60.05
-0.2459
0.0699
0.3158
760.4365
0.14684
-346.821466
-346.813724
-346.81278
-346.853274
27.731
COC1(C)COC1
COC1(C)COC1
true
CCC1(C)CCC1
C1COC1
102.133
26.233
0.4217
2
0
78,294
2.75019
1.35686
1.11741
1.289
87.9
-0.1937
0.0837
0.2774
1,226.0888
0.192012
-367.133566
-367.124222
-367.123278
-367.166764
36.541
CN1C2C1C1(C)CC21C
CN1C2C1C1(C)CC21C
true
CC1C2C1C1(C)CC21C
C1C2C1C1NC21
123.199
36.17
1.0989
1
0
38,220
3.26451
1.77789
1.43097
1.9647
75.5
-0.2478
0.0245
0.2724
933.8874
0.151324
-401.901907
-401.895539
-401.894595
-401.932436
26.891
C1C2CC11OC=NCC21
C1=NCC2C3CC2(C3)O1
false
C1CCC23CC(C2)C3C1
C1=NCC2C3CC2(C3)O1
123.155
33.389
0.8235
2
0
132,062
2.39878
1.89396
1.05888
3.9695
65.87
-0.2152
-0.03
0.1852
1,014.4452
0.090933
-494.099833
-494.092476
-494.091532
-494.13154
28.013
NC1=C(F)C(=O)NC=N1
Nc1nc[nH]c(=O)c1F
false
CC1CCCC(C)C1C
O=c1ccnc[nH]1
129.094
29.2281
-0.5088
3
2
79,416
3.14629
1.51343
1.23267
3.7261
76.13
-0.2384
0.0033
0.2417
1,035.3144
0.136262
-417.873994
-417.866328
-417.865383
-417.906236
29.195
CN1C2C3CC2(N3)C1=O
CN1C(=O)C23CC(N2)C13
false
CC1C(C)C23CC(C2)C13
O=C1NC2C3CC12N3
124.143
30.8297
-1.0587
2
1
21,613
3.9633
2.05385
1.353
5.7845
62.57
-0.2367
-0.0728
0.1639
826.8919
0.084448
-410.824178
-410.817233
-410.816289
-410.855574
25.325
NC1=NC(=N)ON=C1
N=c1nc(N)cno1
false
CC1CCCC(C)C1
N=c1nccno1
112.092
24.5651
-0.86873
5
2
26,515
3.78022
1.5578
1.28509
3.8426
78.06
-0.215
0.0097
0.2247
997.2635
0.137908
-380.846923
-380.839824
-380.83888
-380.878186
28.192
CC12CC1C1=NC=CN21
CC12CC1c1nccn12
false
CC12CC1C1CCCC12
c1cn2c(n1)C1CC12
120.155
33.233
1.0992
2
0
22,487
3.12217
0.70409
0.61288
2.3316
80.35
-0.2457
-0.0253
0.2204
1,802.5302
0.167596
-440.26004
-440.249332
-440.248388
-440.297407
37.072
CCC(CCC=O)=NO
CCC(CCC=O)=NO
true
CCCCC(CC)CC
129.159
34.8105
1.2057
3
1
20,343
5.19707
2.24055
1.5811
2.6004
70.33
-0.2161
-0.026
0.1901
757.1159
0.111329
-341.613845
-341.608277
-341.607332
-341.643352
22.115
C1C=CC2=CC=NN12
C1=Cc2ccnn2C1
false
C1CC2CCCC2C1
C1=Cc2ccnn2C1
106.128
31.261
0.9099
2
0
67,402
2.72335
1.55849
1.29161
4.8076
78.29
-0.2441
0.0089
0.253
1,029.9555
0.13721
-380.825521
-380.817852
-380.816908
-380.857558
29.643
CC12C3CC1NC23C#N
CC12C3CC1C2(C#N)N3
false
CCC12CC3CC1C32C
C1C2NC3C1C23
120.155
31.4817
0.26038
2
1
37,014
3.62468
1.09523
1.06625
1.4172
72.2
-0.2485
0.0435
0.292
1,188.9416
0.147409
-438.999657
-438.991615
-438.990671
-439.032853
29.745
C1OCC11NC11COC1
C1OCC12NC21COC1
false
C1CC2(C1)CC21CCC1
C1OCC12NC21COC1
127.143
30.2357
-0.8724
3
1
80,490
2.07844
1.44879
1.22069
4.4532
84.9
-0.2633
0.0195
0.2828
1,167.3425
0.171028
-366.010061
-366.001015
-366.000071
-366.04344
34.289
CC1C2CC(C)C12C#N
CC1CC2C(C)C12C#N
false
CCC12C(C)CC1C2C
C1CC2CC12
121.183
34.481
1.80208
1
0
4,890
5.03023
1.51941
1.20822
3.893
56.73
-0.2058
0.036
0.2418
937.4125
0.095282
-435.775534
-435.768069
-435.767125
-435.807833
26.165
COC1=CNC(=O)O1
COc1c[nH]c(=O)o1
false
CCC1CCC(C)C1
O=c1[nH]cco1
115.088
25.8807
-0.0235
3
1
114,999
3.20862
0.99416
0.80073
2.2077
80.35
-0.2407
0.017
0.2577
1,431.9794
0.183149
-424.234863
-424.225642
-424.224697
-424.268742
35.166
OCC1CC=CC(O)C1
OCC1CC=CC(O)C1
true
CCC1CCCC(C)C1
C1=CCCCC1
128.171
34.9566
0.3058
2
2
91,449
2.46611
1.68069
1.2925
1.8804
79
-0.2334
0.0027
0.2361
1,063.4296
0.171568
-403.151205
-403.142684
-403.14174
-403.183848
33.123
CC1CC2NC1(C)C2=O
CC1CC2NC1(C)C2=O
true
CC1CC2CC1(C)C2C
O=C1C2CCC1N2
125.171
34.1167
0.3258
2
1
87,771
3.60368
1.05864
1.04794
1.2226
83.6
-0.2362
0.0821
0.3183
1,272.4713
0.181366
-387.045095
-387.036179
-387.035235
-387.078193
35.198
CC1CC11CC2(O)CC12
CC1CC12CC1(O)CC12
false
CC1CC12CC1(C)CC12
C1C2CC3(CC3)C12
124.183
33.8878
1.1673
1
1
50,733
2.49287
1.40029
0.96657
3.8734
75.51
-0.2423
-0.0274
0.2149
1,216.9911
0.15946
-423.076402
-423.067872
-423.066928
-423.110215
31.646
O=CC1CCCCC1=O
O=CC1CCCCC1=O
true
CCC1CCCCC1C
O=C1CCCCC1
126.155
33.029
0.9446
2
0
1,443
7.65509
1.45124
1.23851
4.5508
59.79
-0.2511
-0.0189
0.2322
938.2088
0.125042
-341.875439
-341.867667
-341.866722
-341.907737
26.874
CCC(=N)NC=O
CCC(=N)NC=O
true
CCCC(C)CC
100.121
27.2174
0.11967
2
2
789
9.95029
3.94579
2.82538
2.7179
35.95
-0.2744
-0.0275
0.2469
412.1914
0.0514
-337.28389
-337.279525
-337.27858
-337.311504
15.356
OC1=NOC=N1
Oc1ncon1
false
CC1CCCC1
c1ncon1
86.05
15.9628
-0.2248
4
1
132,643
3.19402
1.36673
0.95773
3.7437
69.43
-0.2002
-0.0105
0.1897
1,109.5683
0.101674
-478.04122
-478.033653
-478.032708
-478.072944
29.612
NC1=NC(F)=CC=C1O
Nc1nc(F)ccc1O
false
CC1CCC(C)C(C)C1
c1ccncc1
128.106
30.2722
0.5085
3
2
73,248
2.33505
1.91903
1.39319
2.4143
64.38
-0.2542
0.0095
0.2638
946.6173
0.125838
-475.042551
-475.035038
-475.034093
-475.074525
28.824
OC12COC1CNC2=O
O=C1NCC2OCC12O
false
CC1CCC2CCC12C
O=C1NCC2OCC12
129.115
27.6995
-1.7539
3
2
26,605
2.42962
1.90465
1.07158
1.698
76.21
-0.1862
-0.0297
0.1565
1,045.629
0.115276
-450.16761
-450.159756
-450.158812
-450.19965
30.337
NC1=C(N)C(=N)OC=N1
N=c1ocnc(N)c1N
false
CC1CCCC(C)C1C
N=c1ccnco1
126.119
31.1825
-0.68153
5
3
120,927
3.22958
0.89393
0.8064
2.8454
78.97
-0.2448
0.0801
0.3249
1,497.4187
0.180685
-424.189754
-424.180089
-424.179145
-424.224588
35.634
CC12OC1CC2CCO
CC12OC1CC2CCO
true
CCCC1CC2CC12C
C1CC2OC12
128.171
33.0878
0.5462
2
1
55,436
2.79943
1.56577
1.02163
2.4483
67.27
-0.2491
0.0217
0.2709
1,099.742
0.126563
-471.275988
-471.26782
-471.266875
-471.309223
29.934
NC(=O)N1CCOC1=N
N=C1OCCN1C(N)=O
false
CC(C)C1CCCC1C
N=C1NCCO1
129.119
29.9681
-0.66793
3
2
20,048
5.4572
1.42977
1.25145
2.2695
66.38
-0.2128
0.0195
0.2323
972.978
0.132277
-379.907274
-379.900056
-379.899112
-379.93919
26.319
C1OC1C1=NCCN1
C1CNC(C2CO2)=N1
false
C1CCC(C2CC2)C1
C1CNC(C2CO2)=N1
112.132
30.0447
-0.6131
3
1
61,470
3.37911
0.88616
0.74591
7.0753
68.93
-0.2501
0.0259
0.276
1,474.8544
0.147377
-476.230494
-476.221468
-476.220524
-476.265147
32.753
[NH3+]C(CC([O-])=O)C1CO1
[NH3+]C(CC(=O)[O-])C1CO1
false
CC(C)CC(C)C1CC1
C1CO1
131.131
26.0401
-2.8643
3
1
33,060
4.39839
0.82608
0.72882
2.4104
73.44
-0.1913
0.0283
0.2197
1,509.9463
0.135946
-455.164507
-455.155421
-455.154476
-455.199202
32.632
OCCC1=CNC(=N)O1
N=c1[nH]cc(CCO)o1
false
CCCC1CCC(C)C1
N=c1[nH]cco1
128.131
29.7032
-0.37803
3
3
105,510
2.11899
1.3265
1.17818
1.8211
80.61
-0.2495
0.0748
0.3243
1,242.6632
0.204507
-425.415149
-425.405007
-425.404063
-425.449914
38.124
CC(C)C1(CO)CCO1
CC(C)C1(CO)CCO1
true
CCC1(C(C)C)CCC1
C1COC1
130.187
35.2238
0.7938
2
1
63,563
2.55636
1.46299
1.11573
3.2874
77.6
-0.2407
-0.0369
0.2038
1,154.3823
0.155979
-423.028666
-423.019372
-423.018427
-423.062532
34.597
CC1(C)OC11CCC1=O
CC1(C)OC12CCC2=O
false
CC1CCC12CC2(C)C
O=C1CCC12CO2
126.155
32.136
0.8969
2
0