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10.1073/pnas.1818598116 | 10.1073/pnas.1818598116 | Calpain drives pyroptotic vimentin cleavage, intermediate filament loss, and cell rupture that mediates immunostimulation | 2,019 | 2019-03-12 | journal-article | National Academy of Sciences | Proceedings of the National Academy of Sciences | 116 | 11 | 5061-5070 | 0027-8424, 1091-6490 | null | Michael A. Davis, Marian R. Fairgrieve, Andreas Den Hartigh, Olga Yakovenko, Bhargavi Duvvuri, Christian Lood, Wendy E. Thomas, Susan L. Fink, Michael Gale | 9 | Department of Immunology, University of Washington, Seattle, WA 98109; | 102 | 52 | true | https://www.pnas.org/site/aboutpnas/licenses.xhtml | HHS | NIH | National Institute of Allergy and Infectious Diseases, HHS | NIH | National Institute of Allergy and Infectious Diseases, HHS | NIH | National Institute of Allergy and Infectious Diseases, HHS | NIH | National Institute of Allergy and Infectious Diseases, HHS | NIH | National Institute of Allergy and Infect... | 10.13039/100000060, 10.13039/100000060, 10.13039/100000060, 10.13039/100000060, 10.13039/100000060, 10.13039/100000060, 10.13039/100000060, 10.13039/100007820 | https://doi.org/10.1073/pnas.1818598116 | null | Significance Pyroptosis is a form of inflammatory cell death. It is driven by plasma membrane pore formation that is thought to rupture cells through osmotic influx, thereby releasing intracellular content that initiates an inflammatory response to fight acute infection and tissue damage. However, when chronic or unreg... | null | en | vFRQTig20ipQvrnx6 | uifn0WjQHe13ejlOC |
10.1073/pnas.1421784112 | 10.1073/pnas.1421784112 | Genome-wide ancestry of 17th-century enslaved Africans from the Caribbean | 2,015 | 2015-03-24 | journal-article | National Academy of Sciences | Proceedings of the National Academy of Sciences | 112 | 12 | 3669-3673 | 0027-8424, 1091-6490 | null | Hannes Schroeder, María C. Ávila-Arcos, Anna-Sapfo Malaspinas, G. David Poznik, Marcela Sandoval-Velasco, Meredith L. Carpenter, José Víctor Moreno-Mayar, Martin Sikora, Philip L. F. Johnson, Morten Erik Allentoft, José Alfredo Samaniego, Jay B. Haviser, Michael W. Dee, Thomas W. Stafford, Antonio Salas, Ludovic Orland... | 19 | Centre for Geogenetics, Natural History Museum of Denmark, University of Copenhagen, 1350 Copenhagen, Denmark; | 109 | 44 | true | http://www.pnas.org/site/misc/userlicense.xhtml | European Commission Directorate-General for Research and Innovation, EC | European Research Council, European Commission Directorate-General for Research and Innovation, EC | European Research Council, Det Frie Forskningsråd, Lundbeckfonden, NSF | MPS | Division of Mathematical Sciences, NSF | EHR | Division of Graduat... | 10.13039/100004431, 10.13039/501100000781, 10.13039/100004431, 10.13039/501100000781, 10.13039/501100004836, 10.13039/501100003554, 10.13039/100000121, 10.13039/100000082, 10.13039/501100001711, 10.13039/100000002, 10.13039/100000002, 10.13039/501100000275, 10.13039/501100004837, 10.13039/501100001732 | https://doi.org/10.1073/pnas.1421784112 | null | Significance The transatlantic slave trade resulted in the forced movement of over 12 million Africans to the Americas. Although many coastal shipping points are known, they do not necessarily reflect the slaves’ actual ethnic or geographic origins. We obtained genome-wide data from 17th-century remains of three enslav... | null | en | vFRQTig20ipQvrnx6 | uifn0WjQHe13ejlOC |
10.1073/pnas.96.5.2036 | 10.1073/pnas.96.5.2036 | The two-dimensional IR nonlinear spectroscopy of a cyclic penta-peptide in relation to its three-dimensional structure | 1,999 | 1999-03-02 | journal-article | National Academy of Sciences | Proceedings of the National Academy of Sciences | 96 | 5 | 2036-2041 | 0027-8424, 1091-6490 | null | Peter Hamm, Manho Lim, William F. DeGrado, Robin M. Hochstrasser | 4 | Department of Chemistry and Department of
Biochemistry and Biophysics, The Johnson Foundation for Research in
Biophysics, University of Pennsylvania, Philadelphia, PA 19104 | 345 | 16 | true | null | null | null | https://doi.org/10.1073/pnas.96.5.2036 | null | A form of two-dimensional (2D) vibrational spectroscopy, which uses two ultrafast IR laser pulses, is used to examine the structure of a cyclic penta-peptide in solution. Spectrally resolved cross peaks occur in the off-diagonal region of the 2D IR spectrum of the amide I region, analogous to those in 2D NMR spectrosco... | null | en | vFRQTig20ipQvrnx6 | uifn0WjQHe13ejlOC |
10.1073/pnas.94.8.4109 | 10.1073/pnas.94.8.4109 | Disaggregation of Alzheimer β-amyloid by site-directed mAb | 1,997 | 1997-04-15 | journal-article | National Academy of Sciences | Proceedings of the National Academy of Sciences | 94 | 8 | 4109-4112 | 0027-8424, 1091-6490 | null | Beka Solomon, Rela Koppel, Dan Frankel, Eilat Hanan-Aharon | 4 | Department of Molecular Microbiology and Biotechnology, Tel Aviv University, Ramat Aviv 69978, Israel | 341 | 44 | true | null | null | null | https://doi.org/10.1073/pnas.94.8.4109 | null | In Alzheimer disease, β-amyloid peptide accumulates in the brain as insoluble amyloid plaques. Amyloid filaments, similar to those found in amyloid plaques, can be assembled in vitro from chemically synthesized β-peptides. In this study, we report that antibodies raised against the N-terminal region (1–28) of the β-amy... | null | en | vFRQTig20ipQvrnx6 | uifn0WjQHe13ejlOC |
10.1073/pnas.1406763111 | 10.1073/pnas.1406763111 | Contrasted coevolutionary dynamics between a bacterial pathogen and its bacteriophages | 2,014 | 2014-07-29 | journal-article | National Academy of Sciences | Proceedings of the National Academy of Sciences | 111 | 30 | 11109-11114 | 0027-8424, 1091-6490 | null | Alex Betts, Oliver Kaltz, Michael E. Hochberg | 3 | Institut des Sciences de l'Evolution, Université Montpellier II, Unité Mixte de Recherche 5554, 34095 Montpellier Cedex 05, France; | 115 | 69 | true | null | null | null | https://doi.org/10.1073/pnas.1406763111 | null | Significance Scientists have long debated the dynamic form of perpetual reciprocal adaptations, or coevolution, between hosts and their parasites. The two main types of antagonistic coevolution described to date are arms race dynamics, in which interaction traits escalate through time, and fluctuating selection dynamic... | null | en | vFRQTig20ipQvrnx6 | uifn0WjQHe13ejlOC |
10.1073/pnas.2211616119 | 10.1073/pnas.2211616119 | Substitutions near the HA receptor binding site explain the origin and major antigenic change of the B/Victoria and B/Yamagata lineages | 2,022 | 2022-10-18 | journal-article | National Academy of Sciences | Proceedings of the National Academy of Sciences | 119 | 42 | null | 0027-8424, 1091-6490 | null | Miruna E. Rosu, Pascal Lexmond, Theo M. Bestebroer, Blake M. Hauser, Derek J. Smith, Sander Herfst, Ron A. M. Fouchier | 7 | Department of Viroscience, Erasmus Medical Centre, Rotterdam 3015 CE, The Netherlands | 53 | 48 | true | https://creativecommons.org/licenses/by-nc-nd/4.0/ | EC | Horizon 2020 Framework Programme, HHS | NIH | National Institute of Allergy and Infectious Diseases | 10.13039/100010661, 10.13039/100000060 | https://doi.org/10.1073/pnas.2211616119 | null | Influenza B virus primarily infects humans, causing seasonal epidemics globally. Two antigenic variants—Victoria-like and Yamagata-like—were detected in the 1980s, of which the molecular basis of emergence is still incompletely understood. Here, the antigenic properties of a unique collection of historical virus isolat... | null | en | vFRQTig20ipQvrnx6 | uifn0WjQHe13ejlOC |
10.1073/pnas.1318738111 | 10.1073/pnas.1318738111 | Noise differentially impacts phoneme representations in the auditory and speech motor systems | 2,014 | 2014-05-13 | journal-article | National Academy of Sciences | Proceedings of the National Academy of Sciences | 111 | 19 | 7126-7131 | 0027-8424, 1091-6490 | null | Yi Du, Bradley R. Buchsbaum, Cheryl L. Grady, Claude Alain | 4 | Rotman Research Institute, Baycrest Centre for Geriatric Care, Toronto, ON, Canada M6A 2E1; and | 209 | 37 | true | null | null | null | https://doi.org/10.1073/pnas.1318738111 | null | Significance Contentious debate remains regarding the role of the redundant motor activation during speech perception. In this functional MRI study, multivariate pattern analysis revealed stronger multivoxel phoneme discrimination in speech motor regions than auditory cortices when the speech phonemes were moderately d... | null | en | vFRQTig20ipQvrnx6 | uifn0WjQHe13ejlOC |
10.1073/pnas.0503017102 | 10.1073/pnas.0503017102 | ELL-associated factors 1 and 2 are positive regulators of RNA polymerase II elongation factor ELL | 2,005 | 2005-07-19 | journal-article | National Academy of Sciences | Proceedings of the National Academy of Sciences | 102 | 29 | 10094-10098 | 0027-8424, 1091-6490 | null | Stephanie E. Kong, Charles A. S. Banks, Ali Shilatifard, Joan Weliky Conaway, Ronald C. Conaway | 5 | Stowers Institute for Medical Research, Kansas City, MO 64110; Edward A. Doisy Department of Biochemistry and Molecular Biology, St. Louis University Health Sciences Center, St. Louis, MO 63104; Department of Biochemistry and Molecular Biology, Kansas University Medical Center, Kansas City, KS 66160; and Department of ... | 87 | 22 | true | null | null | null | https://doi.org/10.1073/pnas.0503017102 | null | In human cells, the ELL family of transcription factors includes at least three members, which are all capable of stimulating the overall rate of elongation by RNA polymerase II by suppressing transient pausing by the enzyme at many sites along DNA. In this report, we identify the ELL-associated factors (EAF)1 and EAF2... | null | en | vFRQTig20ipQvrnx6 | uifn0WjQHe13ejlOC |
10.1073/pnas.2312556121 | 10.1073/pnas.2312556121 | Spatiotemporal trends of hemorrhagic fever with renal syndrome (HFRS) in China under climate variation | 2,024 | 2024-01-23 | journal-article | National Academy of Sciences | Proceedings of the National Academy of Sciences | 121 | 4 | null | 0027-8424, 1091-6490 | null | Yuchen Wang, Chutian Zhang, Jing Gao, Ziqi Chen, Zhao Liu, Jianbin Huang, Yidan Chen, Zhichao Li, Nan Chang, Yuxin Tao, Hui Tang, Xuejie Gao, Ying Xu, Can Wang, Dong Li, Xiaobo Liu, Jingxiang Pan, Wenjia Cai, Peng Gong, Yong Luo, Wannian Liang, Qiyong Liu, Nils Chr. Stenseth, Ruifu Yang, Lei Xu | 25 | Vanke School of Public Health, Tsinghua University, Beijing 100084, China | 33 | 56 | true | https://creativecommons.org/licenses/by-nc-nd/4.0/ | null | null | https://doi.org/10.1073/pnas.2312556121 | null | Hemorrhagic fever with renal syndrome (HFRS) is a zoonotic disease caused by the rodent-transmitted orthohantaviruses (HVs), with China possessing the most cases globally. The virus hosts in China are Apodemus agrarius and Rattus norvegicus , and the disease spread is strongly influenced by global climate dynamics. To ... | null | en | vFRQTig20ipQvrnx6 | uifn0WjQHe13ejlOC |
10.1073/pnas.1903579116 | 10.1073/pnas.1903579116 | A pair of native fungal pathogens drives decline of a new invasive herbivore | 2,019 | 2019-05-07 | journal-article | National Academy of Sciences | Proceedings of the National Academy of Sciences | 116 | 19 | 9178-9180 | 0027-8424, 1091-6490 | null | Eric H. Clifton, Louela A. Castrillo, Andrii Gryganskyi, Ann E. Hajek | 4 | Department of Entomology, Cornell University, Ithaca, NY 14853-2601; | 50 | 25 | true | https://creativecommons.org/licenses/by-nc-nd/4.0/ | USDA | Animal and Plant Health Inspection Service, USDA | U.S. Forest Service | 10.13039/100009168, 10.13039/100006959 | https://doi.org/10.1073/pnas.1903579116 | null | Two North American fungal pathogens caused a coepizootic leading to localized collapse of an outbreak population of the newly invasive planthopper pest, the spotted lanternfly ( Lycorma delicatula ), in the eastern United States. The pathogens partitioned the habitat, with the majority of L. delicatula on tree trunks k... | null | en | vFRQTig20ipQvrnx6 | uifn0WjQHe13ejlOC |
10.1073/pnas.2507837122 | 10.1073/pnas.2507837122 | Fossil fuel methane emissions likely underestimated in a model based on atmospheric δ <sup>13</sup> C trends | 2,025 | 2025-06-24 | journal-article | National Academy of Sciences | Proceedings of the National Academy of Sciences | 122 | 25 | null | 0027-8424, 1091-6490 | null | Benjamin T. Uveges, Robert W. Howarth, Jed P. Sparks | 3 | Department of Ecology and Evolutionary Biology, Cornell University | 2 | 10 | true | https://creativecommons.org/licenses/by/4.0/ | null | null | https://doi.org/10.1073/pnas.2507837122 | null | null | null | en | vFRQTig20ipQvrnx6 | uifn0WjQHe13ejlOC |
10.1073/pnas.2216192120 | 10.1073/pnas.2216192120 | Distinct early and late neural mechanisms regulate feature-specific sensory adaptation in the human visual system | 2,023 | 2023-02-07 | journal-article | National Academy of Sciences | Proceedings of the National Academy of Sciences | 120 | 6 | null | 0027-8424, 1091-6490 | null | Reuben Rideaux, Rebecca K. West, Dragan Rangelov, Jason B. Mattingley | 4 | Queensland Brain Institute, The University of Queensland, St. Lucia 4072, Australia | 47 | 48 | true | https://creativecommons.org/licenses/by-nc-nd/4.0/ | Department of Education and Training | Australian Research Council, DHAC | National Health and Medical Research Council, DHAC | National Health and Medical Research Council | 10.13039/501100000923, 10.13039/501100000925, 10.13039/501100000925 | https://doi.org/10.1073/pnas.2216192120 | null | A canonical feature of sensory systems is that they adapt to prolonged or repeated inputs, suggesting the brain encodes the temporal context in which stimuli are embedded. Sensory adaptation has been observed in the central nervous systems of many animal species, using techniques sensitive to a broad range of spatiotem... | null | en | vFRQTig20ipQvrnx6 | uifn0WjQHe13ejlOC |
10.1073/pnas.0401343101 | 10.1073/pnas.0401343101 | CCAAT displacement protein/ <i>cut</i> homolog recruits G9a histone lysine methyltransferase to repress transcription | 2,004 | 2004-08-03 | journal-article | National Academy of Sciences | Proceedings of the National Academy of Sciences | 101 | 31 | 11257-11262 | 0027-8424, 1091-6490 | null | Hitomi Nishio, Martin J. Walsh | 2 | Department of Pediatrics, Mount Sinai School of Medicine, One Gustave L. Levy Place, New York, NY 10029 | 121 | 37 | true | null | null | null | https://doi.org/10.1073/pnas.0401343101 | null | CCAAT displacement protein/ cut homolog (CDP/ cut ) is a highly conserved homeodomain protein that contains three cut repeat sequences. CDP/ cut is a transcriptional factor for many diverse cellular and viral genes that are involved in most cellular processes, including differentiation, development, and proliferation. ... | null | en | vFRQTig20ipQvrnx6 | uifn0WjQHe13ejlOC |
10.1073/pnas.0911674106 | 10.1073/pnas.0911674106 | Rapid β-lactam-induced lysis requires successful assembly of the cell division machinery | 2,009 | 2009-12-22 | journal-article | National Academy of Sciences | Proceedings of the National Academy of Sciences | 106 | 51 | 21872-21877 | 0027-8424, 1091-6490 | null | Hak Suk Chung, Zhizhong Yao, Nathan W. Goehring, Roy Kishony, Jon Beckwith, Daniel Kahne | 6 | Department of Chemistry and Chemical Biology, Harvard University, Cambridge, MA 02138; and | 117 | 34 | true | null | null | null | https://doi.org/10.1073/pnas.0911674106 | null | β-lactam antibiotics inhibit penicillin binding proteins (PBPs) involved in peptidoglycan synthesis. Although inhibition of peptidoglycan biosynthesis is generally thought to induce cell lysis, the pattern and mechanism of cell lysis can vary substantially. β-lactams that inhibit FtsI, the only division specific PBP, b... | null | en | vFRQTig20ipQvrnx6 | uifn0WjQHe13ejlOC |
10.1073/pnas.2217673120 | 10.1073/pnas.2217673120 | Gaucher disease protects against tuberculosis | 2,023 | 2023-02-14 | journal-article | National Academy of Sciences | Proceedings of the National Academy of Sciences | 120 | 7 | null | 0027-8424, 1091-6490 | null | Jingwen Fan, Victoria L. Hale, Lindsey T. Lelieveld, Laura J. Whitworth, Elisabeth M. Busch-Nentwich, Mark Troll, Paul H. Edelstein, Timothy M. Cox, Francisco J. Roca, Johannes M. F. G. Aerts, Lalita Ramakrishnan | 11 | Molecular Immunity Unit, Cambridge Institute of Therapeutic Immunology and Infectious Diseases, Department of Medicine, University of Cambridge, Cambridge CB2 0QH, UK | 21 | 71 | true | https://creativecommons.org/licenses/by/4.0/ | Wellcome Trust, HHS | NIH | NIAID | Division of Microbiology and Infectious Diseases, National Institute of Allergy and Infectious Diseases, NWO | Nationaal Regieorgaan Onderwijsonderzoek, NIHR | NIHR Cambridge Biomedical Research Centre | 10.13039/100010269, 10.13039/100015691, 10.13039/501100010071, 10.13039/501100018956 | https://doi.org/10.1073/pnas.2217673120 | null | Biallelic mutations in the glucocerebrosidase ( GBA1 ) gene cause Gaucher disease, characterized by lysosomal accumulation of glucosylceramide and glucosylsphingosine in macrophages. Gaucher and other lysosomal diseases occur with high frequency in Ashkenazi Jews. It has been proposed that the underlying mutations conf... | null | en | vFRQTig20ipQvrnx6 | uifn0WjQHe13ejlOC |
10.1073/pnas.2204752119 | 10.1073/pnas.2204752119 | TPL2 kinase expression is regulated by the p38γ/p38δ-dependent association of aconitase-1 with <i>TPL2</i> mRNA | 2,022 | 2022-08-30 | journal-article | National Academy of Sciences | Proceedings of the National Academy of Sciences | 119 | 35 | null | 0027-8424, 1091-6490 | null | Alejandra Escós, José Martín-Gómez, Diego González-Romero, Ester Díaz-Mora, Rosario Francisco-Velilla, Cesar Santiago, José M. Cuezva, Sonia Domínguez-Zorita, Encarnación Martínez-Salas, Nahum Sonenberg, Juan José Sanz-Ezquerro, Seyed Mehdi Jafarnejad, Ana Cuenda | 13 | Department of Immunology and Oncology, Centro Nacional de Biotecnología-Consejo Superior de Investigaciones Científicas (CNB/CSIC) Campus Universidad Autónoma de Madrid (UAM), Madrid, 28049 Spain | 8 | 27 | true | https://creativecommons.org/licenses/by-nc-nd/4.0/ | Ministerio de Ciencia e Innovación, Ministerio de Ciencia e Innovación, Ministerio de Ciencia e Innovación | 10.13039/501100004837, 10.13039/501100004837, 10.13039/501100004837 | https://doi.org/10.1073/pnas.2204752119 | null | p38γ and p38δ (p38γ/p38δ) regulate inflammation, in part by controlling tumor progression locus 2 (TPL2) expression in myeloid cells. Here, we demonstrate that TPL2 protein levels are dramatically reduced in p38γ/p38δ-deficient (p38γ/δ −/− ) cells and tissues without affecting TPL2 messenger ribonucleic acid (mRNA) exp... | null | en | vFRQTig20ipQvrnx6 | uifn0WjQHe13ejlOC |
10.1073/pnas.95.26.15464 | 10.1073/pnas.95.26.15464 | A new Eocene archaeocete (Mammalia, Cetacea) from India and the time of origin of whales | 1,998 | 1998-12-22 | journal-article | National Academy of Sciences | Proceedings of the National Academy of Sciences | 95 | 26 | 15464-15468 | 0027-8424, 1091-6490 | null | Sunil Bajpai, Philip D. Gingerich | 2 | Department of Earth Sciences, University of Roorkee, Roorkee 247667, Uttar Pradesh, India; and Museum of Paleontology and Department of Geological Sciences, University of Michigan, Ann Arbor, MI 48019-1079 | 117 | 31 | true | null | null | null | https://doi.org/10.1073/pnas.95.26.15464 | null | Himalayacetus subathuensis is a new pakicetid archaeocete from the Subathu Formation of northern India. The type dentary has a small mandibular canal indicating a lack of auditory specializations seen in more advanced cetaceans, and it has Pakicetus -like molar teeth suggesting that it fed on fish. Himalayacetus is sig... | null | en | vFRQTig20ipQvrnx6 | uifn0WjQHe13ejlOC |
10.1073/pnas.1819154116 | 10.1073/pnas.1819154116 | <i>Klebsiella oxytoca</i> enterotoxins tilimycin and tilivalline have distinct host DNA-damaging and microtubule-stabilizing activities | 2,019 | 2019-02-26 | journal-article | National Academy of Sciences | Proceedings of the National Academy of Sciences | 116 | 9 | 3774-3783 | 0027-8424, 1091-6490 | null | Katrin Unterhauser, Lisa Pöltl, Georg Schneditz, Sabine Kienesberger, Ronald A. Glabonjat, Maksym Kitsera, Jakob Pletz, Fernando Josa-Prado, Elisabeth Dornisch, Christian Lembacher-Fadum, Sandro Roier, Gregor Gorkiewicz, Daniel Lucena, Isabel Barasoain, Wolfgang Kroutil, Marc Wiedner, Joanna I. Loizou, Rolf Breinbauer,... | 22 | Institute of Molecular Biosciences, University of Graz, A-8010 Graz, Austria; | 77 | 58 | true | https://creativecommons.org/licenses/by-nc-nd/4.0/ | Austrian Science Fund, BioTechMed-Graz, Ministerio de Economica y Competitividad, BioTechMed-Graz | 10.13039/501100002428 | https://doi.org/10.1073/pnas.1819154116 | null | Significance Human gut microbes form a complex community with vast biosynthetic potential. Microbial products and metabolites released in the gut impact human health and disease. However, defining causative relationships between specific bacterial products and disease initiation and progression remains an immense chall... | null | en | vFRQTig20ipQvrnx6 | uifn0WjQHe13ejlOC |
10.1073/pnas.0900701106 | 10.1073/pnas.0900701106 | Ecological modulation of plant defense via phytochrome control of jasmonate sensitivity | 2,009 | 2009-03-24 | journal-article | National Academy of Sciences | Proceedings of the National Academy of Sciences | 106 | 12 | 4935-4940 | 0027-8424, 1091-6490 | null | Javier E. Moreno, Yi Tao, Joanne Chory, Carlos L. Ballaré | 4 | Ifeva, Consejo Nacional de Investigaciones Científicas y Técnicas, and Universidad de Buenos Aires, Avenida San Martín 4453 C1417DSE Buenos Aires, Argentina; and | 251 | 51 | true | null | null | null | https://doi.org/10.1073/pnas.0900701106 | null | For plants, the tradeoff between resource investment in defense and increased growth to out-compete neighbors creates an allocation dilemma. How plants resolve this dilemma, at the mechanistic level, is unclear. We found that Arabidopsis plants produced an attenuated defense phenotype under conditions of crowding and w... | null | en | vFRQTig20ipQvrnx6 | uifn0WjQHe13ejlOC |
10.1073/pnas.1819440116 | 10.1073/pnas.1819440116 | Genetic and molecular analysis of trichome development in <i>Arabis alpina</i> | 2,019 | 2019-06-11 | journal-article | National Academy of Sciences | Proceedings of the National Academy of Sciences | 116 | 24 | 12078-12083 | 0027-8424, 1091-6490 | null | Divykriti Chopra, Mona Mapar, Lisa Stephan, Maria C. Albani, Anna Deneer, George Coupland, Eva-Maria Willing, Swen Schellmann, Korbinian Schneeberger, Christian Fleck, Andrea Schrader, Martin Hülskamp | 12 | Botanical Institute, Biocenter, University of Cologne, 50674 Cologne, Germany; | 33 | 45 | true | https://www.pnas.org/site/aboutpnas/licenses.xhtml | null | null | https://doi.org/10.1073/pnas.1819440116 | null | Significance Typically, comparative developmental studies focus on the question whether key genes are conserved over large evolutionary distances. How the gene regulatory network of a whole developmental process evolves is virtually unknown. This requires a functional comparison of homologous processes in species close... | null | en | vFRQTig20ipQvrnx6 | uifn0WjQHe13ejlOC |
10.1073/pnas.0711731105 | 10.1073/pnas.0711731105 | Stabilization of a β-hairpin in monomeric Alzheimer's amyloid-β peptide inhibits amyloid formation | 2,008 | 2008-04 | journal-article | National Academy of Sciences | Proceedings of the National Academy of Sciences | 105 | 13 | 5099-5104 | 0027-8424, 1091-6490 | null | Wolfgang Hoyer, Caroline Grönwall, Andreas Jonsson, Stefan Ståhl, Torleif Härd | 5 | *Department of Medical Biochemistry and Swedish Nuclear Magnetic Resonance Center, University of Gothenburg, Box 440, SE-405 30 Göteborg, Sweden; | 388 | 41 | true | null | null | null | https://doi.org/10.1073/pnas.0711731105 | null | According to the amyloid hypothesis, the pathogenesis of Alzheimer's disease is triggered by the oligomerization and aggregation of the amyloid-β (Aβ) peptide into protein plaques. Formation of the potentially toxic oligomeric and fibrillar Aβ assemblies is accompanied by a conformational change toward a high content o... | null | en | vFRQTig20ipQvrnx6 | uifn0WjQHe13ejlOC |
10.1073/pnas.1632821100 | 10.1073/pnas.1632821100 | A chemical approach for identifying <i>O</i> -GlcNAc-modified proteins in cells | 2,003 | 2003-08-05 | journal-article | National Academy of Sciences | Proceedings of the National Academy of Sciences | 100 | 16 | 9116-9121 | 0027-8424, 1091-6490 | null | David J. Vocadlo, Howard C. Hang, Eun-Ju Kim, John A. Hanover, Carolyn R. Bertozzi | 5 | Center for New Directions in Organic Synthesis,
Department of Chemistry, and Department of
Molecular and Cell Biology, Material Sciences Division, Lawrence Berkeley
National Laboratory, and Howard Hughes Medical Institute, University of
California, Berkeley, CA 94720; and Laboratory
of Biochemistry and Metabolism,... | 509 | 43 | true | null | null | null | https://doi.org/10.1073/pnas.1632821100 | null | The glycosylation of serine and threonine residues with a single GlcNAc moiety is a dynamic posttranslational modification of many nuclear and cytoplasmic proteins. We describe a chemical strategy directed toward identifying O -GlcNAc-modified proteins from living cells or proteins modified in vitro . We demonstrate, i... | null | en | vFRQTig20ipQvrnx6 | uifn0WjQHe13ejlOC |
10.1073/pnas.2512430122 | 10.1073/pnas.2512430122 | Cryo-EM structure of the prohibitin complex in open conformation | 2,025 | 2025-09-23 | journal-article | National Academy of Sciences | Proceedings of the National Academy of Sciences | 122 | 38 | null | 0027-8424, 1091-6490 | null | Sixing Hong, Zeyuan Guan, Liying Zhang, Jinjin Zhuang, Ling Yan, Yanjun Liu, Zhu Liu, Qiang Wang, Ping Yin | 9 | National Key Laboratory of Crop Genetic Improvement, Hubei Hongshan Laboratory, Huazhong Agricultural University | 11 | 56 | true | https://creativecommons.org/licenses/by-nc-nd/4.0/ | null | null | https://doi.org/10.1073/pnas.2512430122 | null | Prohibitin 1 (PHB1) and Prohibitin 2 (PHB2), two conserved prohibitin members, are primarily localized to the mitochondrial inner membrane (MIM) to form a nanoscale macromolecular prohibitin complex. This prohibitin complex can facilitate the spatial organization of proteins and lipids, thus maintaining cellular metabo... | null | en | vFRQTig20ipQvrnx6 | uifn0WjQHe13ejlOC |
10.1073/pnas.2107771118 | 10.1073/pnas.2107771118 | Eicosanoid regulation of debris-stimulated metastasis | 2,021 | 2021-10-12 | journal-article | National Academy of Sciences | Proceedings of the National Academy of Sciences | 118 | 41 | null | 0027-8424, 1091-6490 | null | Jianjun Deng, Haixia Yang, Victoria M. Haak, Jun Yang, Franciele C. Kipper, Chantal Barksdale, Sung Hee Hwang, Allison Gartung, Diane R. Bielenberg, Selvakumar Subbian, Koc-Kan Ho, Xiang Ye, Daidi Fan, Yongkui Sun, Bruce D. Hammock, Dipak Panigrahy | 16 | Center for Vascular Biology Research, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA 02215; | 24 | 140 | true | https://creativecommons.org/licenses/by/4.0/ | HHS | NIH | National Institute of Environmental Health Sciences, HHS | NIH | National Institute of Environmental Health Sciences, Credit Unions Kids at Heart, Joe Andruzzi Foundation, CJ Buckley Pediatric Brain Tumor Fund | 10.13039/100000066, 10.13039/100000066, 10.13039/100007267 | https://doi.org/10.1073/pnas.2107771118 | null | Significance Cancer therapy, such as chemotherapy, induces tumor cell death (“debris”), which can stimulate metastasis. Chemotherapy-generated debris upregulates soluble epoxide hydrolase (sEH) and the prostaglandin E 2 receptor 4 (EP4), which triggers a macrophage-derived storm of proinflammatory and proangiogenic lip... | null | en | vFRQTig20ipQvrnx6 | uifn0WjQHe13ejlOC |
10.1073/pnas.2114244118 | 10.1073/pnas.2114244118 | Therapeutic IGF-I receptor inhibition alters fibrocyte immune phenotype in thyroid-associated ophthalmopathy | 2,021 | 2021-12-28 | journal-article | National Academy of Sciences | Proceedings of the National Academy of Sciences | 118 | 52 | null | 0027-8424, 1091-6490 | null | Roshini Fernando, Oshadi Caldera, Terry J. Smith | 3 | Department of Ophthalmology and Visual Sciences, Kellogg Eye Center, Division of Metabolism, Endocrinology, and Diabetes, Department of Internal Medicine, University of Michigan Medical School, Ann Arbor, MI 48105 | 44 | 84 | true | https://www.pnas.org/site/aboutpnas/licenses.xhtml | null | null | https://doi.org/10.1073/pnas.2114244118 | null | Significance Teprotumumab, a therapeutic IGF-I receptor inhibitor, dramatically alters the clinical course of thyroid-associated ophthalmopathy (TAO) and has recently become the only medical therapy for TAO thus far approved by the US FDA. Introduction of teprotumumab has resulted in a paradigm shift in the clinical ma... | null | en | vFRQTig20ipQvrnx6 | uifn0WjQHe13ejlOC |
10.1073/pnas.1714977115 | 10.1073/pnas.1714977115 | Phylogenetic classification of the world’s tropical forests | 2,018 | 2018-02-20 | journal-article | National Academy of Sciences | Proceedings of the National Academy of Sciences | 115 | 8 | 1837-1842 | 0027-8424, 1091-6490 | null | J. W. Ferry Slik, Janet Franklin, Víctor Arroyo-Rodríguez, Richard Field, Salomon Aguilar, Nikolay Aguirre, Jorge Ahumada, Shin-Ichiro Aiba, Luciana F. Alves, Anitha K, Andres Avella, Francisco Mora, Gerardo A. Aymard C., Selene Báez, Patricia Balvanera, Meredith L. Bastian, Jean-François Bastin, Peter J. Bellingham, E... | 187 | Environmental and Life Sciences, Faculty of Science, Universiti Brunei Darussalam, Gadong BE1410, Brunei Darussalam; | 132 | 32 | true | https://creativecommons.org/licenses/by-nc-nd/4.0/ | null | null | https://doi.org/10.1073/pnas.1714977115 | null | Significance Identifying and explaining regional differences in tropical forest dynamics, structure, diversity, and composition are critical for anticipating region-specific responses to global environmental change. Floristic classifications are of fundamental importance for these efforts. Here we provide a global trop... | null | en | vFRQTig20ipQvrnx6 | uifn0WjQHe13ejlOC |
10.1073/pnas.1522297113 | 10.1073/pnas.1522297113 | Chromatographically isolated CD63 <sup>+</sup> CD81 <sup>+</sup> extracellular vesicles from mesenchymal stromal cells rescue cognitive impairments after TBI | 2,016 | 2016-01-05 | journal-article | National Academy of Sciences | Proceedings of the National Academy of Sciences | 113 | 1 | 170-175 | 0027-8424, 1091-6490 | null | Dong-ki Kim, Hidetaka Nishida, Su Yeon An, Ashok K. Shetty, Thomas J. Bartosh, Darwin J. Prockop | 6 | Institute for Regenerative Medicine at Scott & White, College of Medicine, Texas A&M Health Science Center, Temple, TX 76502 | 401 | 50 | true | null | null | null | https://doi.org/10.1073/pnas.1522297113 | null | Significance It has gradually been recognized that the vesicles secreted by cells are a major means by which cells communicate with each other. This recognition has stimulated interest in using vesicles to deliver therapeutic agents. The results presented here address several limitations to progress in the field by dev... | null | en | vFRQTig20ipQvrnx6 | uifn0WjQHe13ejlOC |
10.1073/pnas.2406308121 | 10.1073/pnas.2406308121 | Fructose-2,6-bisphosphate restores DNA repair activity of PNKP and ameliorates neurodegenerative symptoms in Huntington’s disease | 2,024 | 2024-09-24 | journal-article | National Academy of Sciences | Proceedings of the National Academy of Sciences | 121 | 39 | null | 0027-8424, 1091-6490 | null | Anirban Chakraborty, Sravan Gopalkrishnashetty Sreenivasmurthy, Wyatt Miller, Weihan Huai, Tapan Biswas, Santi Mohan Mandal, Lisardo Boscá, Balaji Krishnan, Gourisankar Ghosh, Tapas Hazra | 10 | Department of Internal Medicine, University of Texas Medical Branch, Galveston, TX 77555 | 11 | 48 | true | https://creativecommons.org/licenses/by-nc-nd/4.0/ | HHS | NIH | National Institute of Neurological Disorders and Stroke, HHS | NIH | National Institute of Neurological Disorders and Stroke | 10.13039/100000065, 10.13039/100000065 | https://doi.org/10.1073/pnas.2406308121 | null | Huntington’s disease (HD) and spinocerebellar ataxia type 3 (SCA3) are the two most prevalent polyglutamine (polyQ) neurodegenerative diseases, caused by CAG (encoding glutamine) repeat expansion in the coding region of the huntingtin (HTT) and ataxin-3 (ATXN3) proteins, respectively. We have earlier reported that the ... | null | en | vFRQTig20ipQvrnx6 | uifn0WjQHe13ejlOC |
10.1073/pnas.0603694103 | 10.1073/pnas.0603694103 | Human methionine synthase reductase is a molecular chaperone for human methionine synthase | 2,006 | 2006-06-20 | journal-article | National Academy of Sciences | Proceedings of the National Academy of Sciences | 103 | 25 | 9476-9481 | 0027-8424, 1091-6490 | null | Kazuhiro Yamada, Roy A. Gravel, Tetsuo Toraya, Rowena G. Matthews | 4 | *Life Sciences Institute and Department of Biological Chemistry, University of Michigan, Ann Arbor, MI 48109-2216; | 104 | 32 | true | null | null | null | https://doi.org/10.1073/pnas.0603694103 | null | Sustained activity of mammalian methionine synthase (MS) requires MS reductase (MSR), but there have been few studies of the interactions between these two proteins. In this study, recombinant human MS (hMS) and MSR (hMSR) were expressed in baculovirus-infected insect cells and purified to homogeneity. hMSR maintained ... | null | en | vFRQTig20ipQvrnx6 | uifn0WjQHe13ejlOC |
10.1073/pnas.92.10.4427 | 10.1073/pnas.92.10.4427 | Cloning, baculovirus expression, and characterization of a second mouse prolyl 4-hydroxylase alpha-subunit isoform: formation of an alpha 2 beta 2 tetramer with the protein disulfide-isomerase/beta subunit. | 1,995 | 1995-05-09 | journal-article | National Academy of Sciences | Proceedings of the National Academy of Sciences | 92 | 10 | 4427-4431 | 0027-8424, 1091-6490 | null | T Helaakoski, P Annunen, K Vuori, I A MacNeil, T Pihlajaniemi, K I Kivirikko | 6 | Collagen Research Unit, University of Oulu, Finland. | 91 | 0 | true | null | null | null | https://doi.org/10.1073/pnas.92.10.4427 | null | Prolyl 4-hydroxylase (EC 1.14.11.2) catalyzes the posttranslational formation of 4-hydroxyproline in collagens. The vertebrate enzyme is an alpha 2 beta 2 tetramer, the beta subunit of which is a highly unusual multifunctional polypeptide, being identical to protein disulfide-isomerase (EC 5.3.4.1). We report here the ... | null | en | vFRQTig20ipQvrnx6 | uifn0WjQHe13ejlOC |
10.1073/pnas.1815427116 | 10.1073/pnas.1815427116 | Coupling between dynamic 3D tissue architecture and BMP morphogen signaling during <i>Drosophila</i> wing morphogenesis | 2,019 | 2019-03-05 | journal-article | National Academy of Sciences | Proceedings of the National Academy of Sciences | 116 | 10 | 4352-4361 | 0027-8424, 1091-6490 | null | Jinghua Gui, Yunxian Huang, Martin Montanari, Daniel Toddie-Moore, Kenji Kikushima, Stephanie Nix, Yukitaka Ishimoto, Osamu Shimmi | 8 | Institute of Biotechnology, University of Helsinki, 00014 Helsinki, Finland; | 15 | 51 | true | https://creativecommons.org/licenses/by-nc-nd/4.0/ | Suomen Akatemia, Suomen Akatemia, Suomen Akatemia, Suomen Akatemia, Sigrid Juséliuksen Säätiö, MEXT | Japan Society for the Promotion of Science, MEXT | Japan Society for the Promotion of Science, Finnish Cultural Foundation | Etelä-Karjalan Rahasto, University of Helsinki | Helsingin Yliopiston Tiedesäätiö | 10.13039/501100002341, 10.13039/501100002341, 10.13039/501100002341, 10.13039/501100002341, 10.13039/501100006306, 10.13039/501100001691, 10.13039/501100001691, 10.13039/501100005428, 10.13039/100007798 | https://doi.org/10.1073/pnas.1815427116 | null | Significance Tissue morphogenesis is a dynamic process often accompanied by cell patterning and differentiation. Although how conserved growth factor signaling affects cell and tissue shapes has been actively studied, much less is known about how signaling and dynamic morphogenesis are mutually coordinated. Our study s... | null | en | vFRQTig20ipQvrnx6 | uifn0WjQHe13ejlOC |
10.1073/pnas.1802188115 | 10.1073/pnas.1802188115 | Glycosylation-dependent galectin–receptor interactions promote <i>Chlamydia trachomatis</i> infection | 2,018 | 2018-06-26 | journal-article | National Academy of Sciences | Proceedings of the National Academy of Sciences | 115 | 26 | null | 0027-8424, 1091-6490 | null | Agustin L. Lujan, Diego O. Croci, Julián A. Gambarte Tudela, Antonella D. Losinno, Alejandro J. Cagnoni, Karina V. Mariño, María T. Damiani, Gabriel A. Rabinovich | 8 | Laboratorio de Fagocitosis, Instituto de Histología y Embriología de Mendoza, Consejo Nacional de Investigaciones Científicas y Técnicas, Facultad de Ciencias Médicas, Universidad Nacional de Cuyo, C5500 Mendoza, Argentina; | 43 | 59 | true | http://www.pnas.org/site/aboutpnas/licenses.xhtml | MINCyT | Agencia Nacional de Promoción Científica y Tecnológica, MINCyT | Agencia Nacional de Promoción Científica y Tecnológica | 10.13039/501100003074, 10.13039/501100003074 | https://doi.org/10.1073/pnas.1802188115 | null | Significance Chlamydia trachomatis ( Ct ) is the most common bacterium responsible for sexually transmitted infections. It constitutes a major public health burden, with the greatest clinical impact occurring in women of reproductive age. A vast proportion of Ct infections are underestimated because they are asymptomat... | null | en | vFRQTig20ipQvrnx6 | uifn0WjQHe13ejlOC |
10.1073/pnas.2434175100 | 10.1073/pnas.2434175100 | Amino acid substitutions in the thyroglobulin gene are associated with susceptibility to human and murine autoimmune thyroid disease | 2,003 | 2003-12-09 | journal-article | National Academy of Sciences | Proceedings of the National Academy of Sciences | 100 | 25 | 15119-15124 | 0027-8424, 1091-6490 | null | Yoshiyuki Ban, David A. Greenberg, Erlinda Concepcion, Lucy Skrabanek, Ronald Villanueva, Yaron Tomer | 6 | Division of Endocrinology, Diabetes, and Bone Diseases, Department of Medicine, and Institute for Computational Biomedicine, Department of Physiology and Biophysics, Mount Sinai School of Medicine, New York, NY 10029; and Division of Statistical Genetics, Columbia University, New York, NY 10032 | 145 | 61 | true | null | null | null | https://doi.org/10.1073/pnas.2434175100 | null | The 8q24 locus, which contains the thyroglobulin (Tg) gene, was previously shown to be strongly linked with autoimmune thyroid disease (AITD). We sequenced all 48 exons of the Tg gene and identified 14 single-nucleotide polymorphisms (SNPs). Case control association studies demonstrated that an exon 10-12 SNP cluster a... | null | en | vFRQTig20ipQvrnx6 | uifn0WjQHe13ejlOC |
10.1073/pnas.1711408114 | 10.1073/pnas.1711408114 | Dual function for Tango1 in secretion of bulky cargo and in ER-Golgi morphology | 2,017 | 2017-11-28 | journal-article | National Academy of Sciences | Proceedings of the National Academy of Sciences | 114 | 48 | null | 0027-8424, 1091-6490 | null | L. D. Ríos-Barrera, S. Sigurbjörnsdóttir, M. Baer, M. Leptin | 4 | Directors' Research Unit, European Molecular Biology Laboratory, 69117 Heidelberg, Germany; | 54 | 44 | true | https://creativecommons.org/licenses/by-nc-nd/4.0/ | Deutsche Forschungsgemeinschaft, European Molecular Biology Organization, EMBL Interdisciplinary Postdoctoral Programme, NRW Graduate School for Genetics and Functional Genomics | 10.13039/501100001659, 10.13039/100004410 | https://doi.org/10.1073/pnas.1711408114 | null | Significance Exporting bulky molecules poses challenges for cells, since the membrane vesicles that transport normal-sized molecules may not be sufficiently large. The protein Tango1 allows transport vesicles to grow much larger to accommodate bulky cargo. It has been puzzling why many smaller cargos also fail to be tr... | null | en | vFRQTig20ipQvrnx6 | uifn0WjQHe13ejlOC |
10.1073/pnas.2206076119 | 10.1073/pnas.2206076119 | Pan-mitogenomics reveals the genetic basis of cytonuclear conflicts in citrus hybridization, domestication, and diversification | 2,022 | 2022-10-25 | journal-article | National Academy of Sciences | Proceedings of the National Academy of Sciences | 119 | 43 | null | 0027-8424, 1091-6490 | null | Nan Wang, Chaochao Li, Lihua Kuang, Xiaomeng Wu, Kaidong Xie, Andan Zhu, Qiang Xu, Robert M. Larkin, Yongfeng Zhou, Xiuxin Deng, Wenwu Guo | 11 | Key Laboratory of Horticultural Plant Biology (Ministry of Education), Huazhong Agricultural University, Wuhan 430070, China | 54 | 77 | true | https://creativecommons.org/licenses/by-nc-nd/4.0/ | null | null | https://doi.org/10.1073/pnas.2206076119 | null | Although interactions between the cytoplasmic and nuclear genomes occurred during diversification of many plants, the evolutionary conflicts due to cytonuclear interactions are poorly understood in crop breeding. Here, we constructed a pan-mitogenome and identified chimeric open reading frames (ORFs) generated by exten... | null | en | vFRQTig20ipQvrnx6 | uifn0WjQHe13ejlOC |
10.1073/pnas.1113931109 | 10.1073/pnas.1113931109 | Climate change, adaptive cycles, and the persistence of foraging economies during the late Pleistocene/Holocene transition in the Levant | 2,012 | 2012-03-06 | journal-article | National Academy of Sciences | Proceedings of the National Academy of Sciences | 109 | 10 | 3640-3645 | 0027-8424, 1091-6490 | null | Arlene M. Rosen, Isabel Rivera-Collazo | 2 | Institute of Archaeology, University College London, London WC1H 0PY, United Kingdom; and | 143 | 57 | true | null | null | null | https://doi.org/10.1073/pnas.1113931109 | null | Climatic forcing during the Younger Dryas (∼12.9–11.5 ky B.P.) event has become the theoretical basis to explain the origins of agricultural lifestyles in the Levant by suggesting a failure of foraging societies to adjust. This explanation however, does not fit the scarcity of data for predomestication cultivation in t... | null | en | vFRQTig20ipQvrnx6 | uifn0WjQHe13ejlOC |
10.1073/pnas.91.17.8219 | 10.1073/pnas.91.17.8219 | Universal signals control slime mold stalk formation. | 1,994 | 1994-08-16 | journal-article | National Academy of Sciences | Proceedings of the National Academy of Sciences | 91 | 17 | 8219-8223 | 0027-8424, 1091-6490 | null | S van Es, B W Nieuwenhuijsen, F Lenouvel, E M van Deursen, P Schaap | 5 | Cell Biology Unit, University of Leiden, The Netherlands. | 6 | 0 | true | null | null | null | https://doi.org/10.1073/pnas.91.17.8219 | null | The primitive slime mold Dictyostelium minutum does not display oscillations during aggregation, cannot form migrating slugs, and does not form a prestalk/prespore pattern, all of which are characteristic for development of its advanced relative Dictyostelium discoideum. We used D. minutum to investigate whether slime ... | null | en | vFRQTig20ipQvrnx6 | uifn0WjQHe13ejlOC |
10.1073/pnas.2221479120 | 10.1073/pnas.2221479120 | The impact of threshold decision mechanisms of collective behavior on disease spread | 2,023 | 2023-05-09 | journal-article | National Academy of Sciences | Proceedings of the National Academy of Sciences | 120 | 19 | null | 0027-8424, 1091-6490 | null | Bryce Morsky, Felicia Magpantay, Troy Day, Erol Akçay | 4 | Department of Mathematics, Florida State University, Tallahassee, FL 32306 | 49 | 61 | true | https://creativecommons.org/licenses/by-nc-nd/4.0/ | Gouvernement du Canada | Natural Sciences and Engineering Research Council of Canada, United States - Israel Binational Science Foundation | 10.13039/501100000038, 10.13039/100006221 | https://doi.org/10.1073/pnas.2221479120 | null | Humans are a hyper-social species, which greatly impacts the spread of infectious diseases. How do social dynamics impact epidemiology and what are the implications for public health policy? Here, we develop a model of disease transmission that incorporates social dynamics and a behavior that reduces the spread of dise... | null | en | vFRQTig20ipQvrnx6 | uifn0WjQHe13ejlOC |
10.1073/pnas.90.16.7503 | 10.1073/pnas.90.16.7503 | Triplet structure of von Willebrand factor reflects proteolytic degradation of high molecular weight multimers. | 1,993 | 1993-08-15 | journal-article | National Academy of Sciences | Proceedings of the National Academy of Sciences | 90 | 16 | 7503-7507 | 0027-8424, 1091-6490 | null | M Furlan, R Robles, D Affolter, D Meyer, P Baillod, B Lämmle | 6 | Central Hematology Laboratory, Inselspital, University of Bern, Switzerland. | 59 | 0 | true | null | null | null | https://doi.org/10.1073/pnas.90.16.7503 | null | High molecular weight (HMW) and low molecular weight (LMW) forms of von Willebrand factor (vWF) were isolated from normal human plasma in the presence of protease inhibitors. HMW and LMW vWF preparations were subjected to reduction of interdimeric disulfide bridges under mild reducing conditions. Following sodium dodec... | null | en | vFRQTig20ipQvrnx6 | uifn0WjQHe13ejlOC |
10.1073/pnas.0801376105 | 10.1073/pnas.0801376105 | The splicing-factor oncoprotein SF2/ASF activates mTORC1 | 2,008 | 2008-10-07 | journal-article | National Academy of Sciences | Proceedings of the National Academy of Sciences | 105 | 40 | 15323-15327 | 0027-8424, 1091-6490 | null | Rotem Karni, Yoshitaka Hippo, Scott W. Lowe, Adrian R. Krainer | 4 | *Cold Spring Harbor Laboratory and | 110 | 28 | true | null | null | null | https://doi.org/10.1073/pnas.0801376105 | null | The splicing factor SF2/ASF is an oncoprotein that is up-regulated in many cancers and can transform immortal rodent fibroblasts when slightly overexpressed. The mTOR signaling pathway is activated in many cancers, and pharmacological blockers of this pathway are in clinical trials as anticancer drugs. We examined the ... | null | en | vFRQTig20ipQvrnx6 | uifn0WjQHe13ejlOC |
10.1073/pnas.0904361106 | 10.1073/pnas.0904361106 | Selective engagement of G protein coupled receptor kinases (GRKs) encodes distinct functions of biased ligands | 2,009 | 2009-06-16 | journal-article | National Academy of Sciences | Proceedings of the National Academy of Sciences | 106 | 24 | 9649-9654 | 0027-8424, 1091-6490 | null | David A. Zidar, Jonathan D. Violin, Erin J. Whalen, Robert J. Lefkowitz | 4 | Departments of aMedicine, | 243 | 41 | true | null | null | null | https://doi.org/10.1073/pnas.0904361106 | null | CCL19 and CCL21 are endogenous agonists for the seven-transmembrane receptor CCR7. They are equally active in promoting G protein stimulation and chemotaxis. Yet, we find that they result in striking differences in activation of the G protein-coupled receptor kinase (GRK)/ß-arrestin system. CCL19 leads to robust CCR7 p... | null | en | vFRQTig20ipQvrnx6 | uifn0WjQHe13ejlOC |
10.1073/pnas.0801962105 | 10.1073/pnas.0801962105 | A phylogenetic perspective on the distribution of plant diversity | 2,008 | 2008-08-12 | journal-article | National Academy of Sciences | Proceedings of the National Academy of Sciences | 105 | supplement_1 | 11549-11555 | 0027-8424, 1091-6490 | null | Michael J. Donoghue | 1 | Department of Ecology and Evolutionary Biology and Peabody Museum of Natural History, Yale University, P. O. Box 208106, New Haven, CT 06520-8106 | 611 | 81 | true | null | null | null | https://doi.org/10.1073/pnas.0801962105 | null | Phylogenetic studies are revealing that major ecological niches are more conserved through evolutionary history than expected, implying that adaptations to major climate changes have not readily been accomplished in all lineages. Phylogenetic niche conservatism has important consequences for the assembly of both local ... | null | en | vFRQTig20ipQvrnx6 | uifn0WjQHe13ejlOC |
10.1073/pnas.1201884109 | 10.1073/pnas.1201884109 | Adaptive evolution of voltage-gated sodium channels: The first 800 million years | 2,012 | 2012-06-26 | journal-article | National Academy of Sciences | Proceedings of the National Academy of Sciences | 109 | supplement_1 | 10619-10625 | 0027-8424, 1091-6490 | null | Harold H. Zakon | 1 | Section of Neurobiology, University of Texas, Austin, TX 78712; and Marine Biological Laboratory, The Josephine Bay Paul Center for Comparative Molecular Biology and Evolution, Woods Hole, MA 02543 | 150 | 69 | true | null | null | null | https://doi.org/10.1073/pnas.1201884109 | null | Voltage-gated Na + -permeable (Nav) channels form the basis for electrical excitability in animals. Nav channels evolved from Ca 2+ channels and were present in the common ancestor of choanoflagellates and animals, although this channel was likely permeable to both Na + and Ca 2+ . Thus, like many other neuronal channe... | null | en | vFRQTig20ipQvrnx6 | uifn0WjQHe13ejlOC |
10.1073/pnas.0910723107 | 10.1073/pnas.0910723107 | EGCG remodels mature α-synuclein and amyloid-β fibrils and reduces cellular toxicity | 2,010 | 2010-04-27 | journal-article | National Academy of Sciences | Proceedings of the National Academy of Sciences | 107 | 17 | 7710-7715 | 0027-8424, 1091-6490 | null | Jan Bieschke, Jenny Russ, Ralf P. Friedrich, Dagmar E. Ehrnhoefer, Heike Wobst, Katja Neugebauer, Erich E. Wanker | 7 | Max Delbrueck Center for Molecular Medicine, Robert-Roessle-Strasse 10, 13125 Berlin-Buch, Germany | 960 | 29 | true | null | null | null | https://doi.org/10.1073/pnas.0910723107 | null | Protein misfolding and formation of β-sheet-rich amyloid fibrils or aggregates is related to cellular toxicity and decay in various human disorders including Alzheimer’s and Parkinson’s disease. Recently, we demonstrated that the polyphenol (-)-epi-gallocatechine gallate (EGCG) inhibits α-synuclein and amyloid-β fibril... | null | en | vFRQTig20ipQvrnx6 | uifn0WjQHe13ejlOC |
10.1016/j.stem.2017.05.016 | 10.1016/j.stem.2017.05.016 | Opportunities in Reprogramming: Fred Gage, Kristin Baldwin, and Hongkui Deng | 2,017 | 2017-06 | journal-article | Elsevier BV | Cell Stem Cell | 20 | 6 | 767-770 | 1934-5909 | null | null | 0 | null | 0 | 0 | true | https://www.elsevier.com/tdm/userlicense/1.0/ | null | null | https://doi.org/10.1016/j.stem.2017.05.016 | null | null | null | en | n4EmbxwhoIT6ILoGV | an9HQtyrKzMvEcwRO |
10.1016/j.stem.2016.07.008 | 10.1016/j.stem.2016.07.008 | Deteriorating Infrastructure in the Aged Muscle Stem Cell Niche | 2,016 | 2016-08 | journal-article | Elsevier BV | Cell Stem Cell | 19 | 2 | 150-151 | 1934-5909 | null | Joseph T. Rodgers | 1 | null | 0 | 9 | true | https://www.elsevier.com/tdm/userlicense/1.0/ | null | null | https://doi.org/10.1016/j.stem.2016.07.008 | null | null | null | en | n4EmbxwhoIT6ILoGV | an9HQtyrKzMvEcwRO |
10.1016/j.stem.2016.11.013 | 10.1016/j.stem.2016.11.013 | Fetal to Adult Hematopoiesis with the “Flk” of a Switch | 2,016 | 2016-12 | journal-article | Elsevier BV | Cell Stem Cell | 19 | 6 | 673-674 | 1934-5909 | null | Stijn Vanhee, Joan Yuan | 2 | null | 0 | 10 | true | https://www.elsevier.com/tdm/userlicense/1.0/ | null | null | https://doi.org/10.1016/j.stem.2016.11.013 | null | null | null | en | n4EmbxwhoIT6ILoGV | an9HQtyrKzMvEcwRO |
10.1016/j.stem.2015.04.017 | 10.1016/j.stem.2015.04.017 | In This Issue | 2,015 | 2015-05 | journal-article | Elsevier BV | Cell Stem Cell | 16 | 5 | xiii | 1934-5909 | null | null | 0 | null | 0 | 0 | true | https://www.elsevier.com/tdm/userlicense/1.0/ | null | null | https://doi.org/10.1016/j.stem.2015.04.017 | null | null | null | en | n4EmbxwhoIT6ILoGV | an9HQtyrKzMvEcwRO |
10.1016/j.stem.2015.10.011 | 10.1016/j.stem.2015.10.011 | In This Issue | 2,015 | 2015-11 | journal-article | Elsevier BV | Cell Stem Cell | 17 | 5 | xi | 1934-5909 | null | null | 0 | null | 0 | 0 | true | https://www.elsevier.com/tdm/userlicense/1.0/ | null | null | https://doi.org/10.1016/j.stem.2015.10.011 | null | null | null | en | n4EmbxwhoIT6ILoGV | an9HQtyrKzMvEcwRO |
10.1016/j.stem.2018.09.014 | 10.1016/j.stem.2018.09.014 | Mentoring the Next Generation: John Dick | 2,018 | 2018-10 | journal-article | Elsevier BV | Cell Stem Cell | 23 | 4 | 468-470 | 1934-5909 | null | null | 0 | null | 0 | 0 | true | https://www.elsevier.com/tdm/userlicense/1.0/ | null | null | https://doi.org/10.1016/j.stem.2018.09.014 | null | null | null | en | n4EmbxwhoIT6ILoGV | an9HQtyrKzMvEcwRO |
10.1016/j.stem.2014.12.012 | 10.1016/j.stem.2014.12.012 | In This Issue | 2,015 | 2015-01 | journal-article | Elsevier BV | Cell Stem Cell | 16 | 1 | ix | 1934-5909 | null | null | 0 | null | 0 | 0 | true | https://www.elsevier.com/tdm/userlicense/1.0/ | null | null | https://doi.org/10.1016/j.stem.2014.12.012 | null | null | null | en | n4EmbxwhoIT6ILoGV | an9HQtyrKzMvEcwRO |
10.1016/j.stem.2024.04.007 | 10.1016/j.stem.2024.04.007 | Connie Eaves (May 22, 1944–March 7, 2024) | 2,024 | 2024-05 | journal-article | Elsevier BV | Cell Stem Cell | 31 | 5 | 593-596 | 1934-5909 | null | Ali Turhan, Franck Nicolini, François Lemoine, Laure Coulombel, Saghi Ghaffari | 5 | null | 0 | 0 | true | https://www.elsevier.com/tdm/userlicense/1.0/ | null | null | https://doi.org/10.1016/j.stem.2024.04.007 | null | null | null | en | n4EmbxwhoIT6ILoGV | an9HQtyrKzMvEcwRO |
10.1016/j.stem.2010.12.011 | 10.1016/j.stem.2010.12.011 | A Roundabout Way to the Niche | 2,011 | 2011-01 | journal-article | Elsevier BV | Cell Stem Cell | 8 | 1 | 6-7 | 1934-5909 | null | Kateri Moore | 1 | null | 0 | 10 | true | https://www.elsevier.com/tdm/userlicense/1.0/ | null | null | https://doi.org/10.1016/j.stem.2010.12.011 | null | null | null | en | n4EmbxwhoIT6ILoGV | an9HQtyrKzMvEcwRO |
10.1016/j.stem.2014.09.011 | 10.1016/j.stem.2014.09.011 | In This Issue | 2,014 | 2014-10 | journal-article | Elsevier BV | Cell Stem Cell | 15 | 4 | xv | 1934-5909 | null | null | 0 | null | 0 | 0 | true | https://www.elsevier.com/tdm/userlicense/1.0/ | null | null | https://doi.org/10.1016/j.stem.2014.09.011 | null | null | null | en | n4EmbxwhoIT6ILoGV | an9HQtyrKzMvEcwRO |
10.1016/j.stem.2018.10.021 | 10.1016/j.stem.2018.10.021 | Voices: Crossing the Valley of Death | 2,018 | 2018-11 | journal-article | Elsevier BV | Cell Stem Cell | 23 | 5 | 639-641 | 1934-5909 | null | null | 0 | null | 5 | 0 | true | https://www.elsevier.com/tdm/userlicense/1.0/ | null | null | https://doi.org/10.1016/j.stem.2018.10.021 | null | null | null | en | n4EmbxwhoIT6ILoGV | an9HQtyrKzMvEcwRO |
10.1016/j.stem.2013.12.014 | 10.1016/j.stem.2013.12.014 | Differing Standards for the NIH Stem Cell Registry and FDA Approval Render Most Federally Funded hESC Lines Unsuitable for Clinical Use | 2,014 | 2014-02 | journal-article | Elsevier BV | Cell Stem Cell | 14 | 2 | 139-140 | 1934-5909 | null | Erica C. Jonlin | 1 | null | 12 | 4 | true | https://www.elsevier.com/tdm/userlicense/1.0/ | null | null | https://doi.org/10.1016/j.stem.2013.12.014 | null | null | null | en | n4EmbxwhoIT6ILoGV | an9HQtyrKzMvEcwRO |
10.1016/j.stem.2012.05.002 | 10.1016/j.stem.2012.05.002 | A Great Match | 2,012 | 2012-06 | journal-article | Elsevier BV | Cell Stem Cell | 10 | 6 | 638-639 | 1934-5909 | null | Leonard I. Zon | 1 | null | 0 | 0 | true | https://www.elsevier.com/tdm/userlicense/1.0/ | null | null | https://doi.org/10.1016/j.stem.2012.05.002 | null | null | null | en | n4EmbxwhoIT6ILoGV | an9HQtyrKzMvEcwRO |
10.1016/j.stem.2011.12.014 | 10.1016/j.stem.2011.12.014 | Untapping the Potential of Human Retinal Pigmented Epithelial Cells | 2,012 | 2012-01 | journal-article | Elsevier BV | Cell Stem Cell | 10 | 1 | 1-2 | 1934-5909 | null | Pete Coffey | 1 | null | 4 | 4 | true | https://www.elsevier.com/tdm/userlicense/1.0/ | null | null | https://doi.org/10.1016/j.stem.2011.12.014 | null | null | null | en | n4EmbxwhoIT6ILoGV | an9HQtyrKzMvEcwRO |
10.1016/j.stem.2016.11.007 | 10.1016/j.stem.2016.11.007 | A Quiescent Bcl11b High Stem Cell Population Is Required for Maintenance of the Mammary Gland | 2,017 | 2017-02 | journal-article | Elsevier BV | Cell Stem Cell | 20 | 2 | 247-260.e5 | 1934-5909 | null | Shang Cai, Tomer Kalisky, Debashis Sahoo, Piero Dalerba, Weiguo Feng, Yuan Lin, Dalong Qian, Angela Kong, Jeffrey Yu, Flora Wang, Elizabeth Y. Chen, Ferenc A. Scheeren, Angera H. Kuo, Shaheen S. Sikandar, Shigeo Hisamori, Linda J. van Weele, Diane Heiser, Sopheak Sim, Jessica Lam, Stephen Quake, Michael F. Clarke | 21 | null | 96 | 60 | true | https://www.elsevier.com/tdm/userlicense/1.0/ | National Cancer Institute, National Cancer Institute, National Cancer Institute, Breast Cancer Research Foundation, California Institute of Regenerative Medicine, U.S. Department of Defense, National Institutes of Health | 10.13039/100000054, 10.13039/100000054, 10.13039/100000054, 10.13039/100001006, 10.13039/100007557, 10.13039/100000005, 10.13039/100000002 | https://doi.org/10.1016/j.stem.2016.11.007 | null | null | null | en | n4EmbxwhoIT6ILoGV | an9HQtyrKzMvEcwRO |
10.1016/j.stem.2011.05.008 | 10.1016/j.stem.2011.05.008 | Notch and Basal Cells Take Center Stage during Airway Epithelial Regeneration | 2,011 | 2011-06 | journal-article | Elsevier BV | Cell Stem Cell | 8 | 6 | 597-598 | 1934-5909 | null | Jeffrey A. Whitsett, Vladimir V. Kalinichenko | 2 | null | 19 | 10 | true | https://www.elsevier.com/tdm/userlicense/1.0/ | null | null | https://doi.org/10.1016/j.stem.2011.05.008 | null | null | null | en | n4EmbxwhoIT6ILoGV | an9HQtyrKzMvEcwRO |
10.1016/j.stem.2025.03.006 | 10.1016/j.stem.2025.03.006 | EZH1 repression generates mature iPSC-derived CAR T cells with enhanced antitumor activity | 2,025 | 2025-04 | journal-article | Elsevier BV | Cell Stem Cell | 32 | 4 | 670 | 1934-5909 | null | Ran Jing, Irene Scarfo, Mohamad Ali Najia, Edroaldo Lummertz da Rocha, Areum Han, Michael Sanborn, Trevor Bingham, Caroline Kubaczka, Deepak K. Jha, Marcelo Falchetti, Thorsten M. Schlaeger, Trista E. North, Marcela V. Maus, George Q. Daley | 14 | null | 3 | 0 | true | https://www.elsevier.com/tdm/userlicense/1.0/ | null | null | https://doi.org/10.1016/j.stem.2025.03.006 | null | null | null | en | n4EmbxwhoIT6ILoGV | an9HQtyrKzMvEcwRO |
10.1016/j.stem.2024.09.004 | 10.1016/j.stem.2024.09.004 | Marmoset and human trophoblast stem cells differ in signaling requirements and recapitulate divergent modes of trophoblast invasion | 2,024 | 2024-10 | journal-article | Elsevier BV | Cell Stem Cell | 31 | 10 | 1427-1446.e8 | 1934-5909 | null | Dylan Siriwardena, Clara Munger, Christopher Penfold, Timo N. Kohler, Antonia Weberling, Madeleine Linneberg-Agerholm, Erin Slatery, Anna L. Ellermann, Sophie Bergmann, Stephen J. Clark, Thomas M. Rawlings, Joshua M. Brickman, Wolf Reik, Jan J. Brosens, Magdalena Zernicka-Goetz, Erika Sasaki, Rüdiger Behr, Florian Holl... | 19 | null | 12 | 101 | true | https://www.elsevier.com/tdm/userlicense/1.0/ | University of Cambridge Centre for Trophoblast Research, Wellcome Trust | 10.13039/501100018958, 10.13039/100010269 | https://doi.org/10.1016/j.stem.2024.09.004 | null | null | null | en | n4EmbxwhoIT6ILoGV | an9HQtyrKzMvEcwRO |
10.1016/j.stem.2013.01.013 | 10.1016/j.stem.2013.01.013 | The Young and the Restless: Regulation of Adult Neurogenesis by Wnt Signaling | 2,013 | 2013-02 | journal-article | Elsevier BV | Cell Stem Cell | 12 | 2 | 139-140 | 1934-5909 | null | Melody V. Wu, René Hen | 2 | null | 9 | 10 | true | https://www.elsevier.com/tdm/userlicense/1.0/ | null | null | https://doi.org/10.1016/j.stem.2013.01.013 | null | null | null | en | n4EmbxwhoIT6ILoGV | an9HQtyrKzMvEcwRO |
10.1016/j.stem.2014.03.007 | 10.1016/j.stem.2014.03.007 | How Tets and Cytoskeleton Dynamics MET in Reprogramming | 2,014 | 2014-04 | journal-article | Elsevier BV | Cell Stem Cell | 14 | 4 | 417-418 | 1934-5909 | null | Laurent David, Calley L. Hirsch | 2 | null | 1 | 10 | true | https://www.elsevier.com/tdm/userlicense/1.0/ | null | null | https://doi.org/10.1016/j.stem.2014.03.007 | null | null | null | en | n4EmbxwhoIT6ILoGV | an9HQtyrKzMvEcwRO |
10.1016/j.stem.2019.08.010 | 10.1016/j.stem.2019.08.010 | Institutional Report Cards for Gender Equality: Lessons Learned from Benchmarking Efforts for Women in STEM | 2,019 | 2019-09 | journal-article | Elsevier BV | Cell Stem Cell | 25 | 3 | 306-310 | 1934-5909 | null | Whitney H. Beeler, Kristin A. Smith-Doody, Richard Ha, Raeka S. Aiyar, Elizabeth Schwarzbach, Susan L. Solomon, Reshma Jagsi | 7 | null | 17 | 9 | true | https://www.elsevier.com/tdm/userlicense/1.0/ | New York Stem Cell Foundation | 10.13039/100003194 | https://doi.org/10.1016/j.stem.2019.08.010 | null | null | null | en | n4EmbxwhoIT6ILoGV | an9HQtyrKzMvEcwRO |
10.1016/j.stem.2020.06.023 | 10.1016/j.stem.2020.06.023 | Mapping Gene Circuits Essential for Germ Layer Differentiation via Loss-of-Function Screens in Haploid Human Embryonic Stem Cells | 2,020 | 2020-10 | journal-article | Elsevier BV | Cell Stem Cell | 27 | 4 | 679-691.e6 | 1934-5909 | null | Atilgan Yilmaz, Carmel Braverman-Gross, Anna Bialer-Tsypin, Mordecai Peretz, Nissim Benvenisty | 5 | null | 40 | 51 | true | https://www.elsevier.com/tdm/userlicense/1.0/ | Israel Science Foundation, Rosetrees Trust, United States-Israel Binational Science Foundation, Azrieli Foundation | 10.13039/501100003977, 10.13039/501100000833, 10.13039/501100001742, 10.13039/501100005155 | https://doi.org/10.1016/j.stem.2020.06.023 | null | null | null | en | n4EmbxwhoIT6ILoGV | an9HQtyrKzMvEcwRO |
10.1016/j.stem.2020.01.003 | 10.1016/j.stem.2020.01.003 | Organoids Develop Motor Skills: 3D Human Neuromuscular Junctions | 2,020 | 2020-02 | journal-article | Elsevier BV | Cell Stem Cell | 26 | 2 | 131-133 | 1934-5909 | null | Justin K. Ichida, Chien-Ping Ko | 2 | null | 8 | 10 | true | https://www.elsevier.com/tdm/userlicense/1.0/ | New York Stem Cell Foundation, Spinal Muscular Atrophy Foundation, National Institutes of Health | 10.13039/100003194, 10.13039/100000894, 10.13039/100000002 | https://doi.org/10.1016/j.stem.2020.01.003 | null | null | null | en | n4EmbxwhoIT6ILoGV | an9HQtyrKzMvEcwRO |
10.1016/j.stem.2018.10.009 | 10.1016/j.stem.2018.10.009 | 20 Years of Human Pluripotent Stem Cell Research: It All Started with Five Lines | 2,018 | 2018-11 | journal-article | Elsevier BV | Cell Stem Cell | 23 | 5 | 644-648 | 1934-5909 | null | Tenneille E. Ludwig, Angela Kujak, Antonio Rauti, Steven Andrzejewski, Susan Langbehn, James Mayfield, Jacqueline Fuller, Yoshimi Yashiro, Yasushi Hara, Anita Bhattacharyya | 10 | null | 17 | 9 | true | https://www.elsevier.com/tdm/userlicense/1.0/ | null | null | https://doi.org/10.1016/j.stem.2018.10.009 | null | null | null | en | n4EmbxwhoIT6ILoGV | an9HQtyrKzMvEcwRO |
10.1016/j.stem.2018.08.015 | 10.1016/j.stem.2018.08.015 | Studying Tumor-ReacTive T Cells: A Personalized Organoid Model | 2,018 | 2018-09 | journal-article | Elsevier BV | Cell Stem Cell | 23 | 3 | 318-319 | 1934-5909 | null | Ugur Sahin | 1 | null | 14 | 10 | true | https://www.elsevier.com/tdm/userlicense/1.0/ | null | null | https://doi.org/10.1016/j.stem.2018.08.015 | null | null | null | en | n4EmbxwhoIT6ILoGV | an9HQtyrKzMvEcwRO |
10.1016/j.stem.2020.09.003 | 10.1016/j.stem.2020.09.003 | The Roadmap to Approval under Japan’s Two-Track Regulatory System: Comparing Six Regenerative Medical Products | 2,020 | 2020-10 | journal-article | Elsevier BV | Cell Stem Cell | 27 | 4 | 515-518 | 1934-5909 | null | Shunsuke Matsushita, Keisuke Tachibana, Tetsuya Kusakabe, Ryuichi Hirayama, Yasuo Tsutsumi, Masuo Kondoh | 6 | null | 10 | 3 | true | https://www.elsevier.com/tdm/userlicense/1.0/ | null | null | https://doi.org/10.1016/j.stem.2020.09.003 | null | null | null | en | n4EmbxwhoIT6ILoGV | an9HQtyrKzMvEcwRO |
10.1016/j.stem.2011.10.011 | 10.1016/j.stem.2011.10.011 | Rewind to Recover: Dedifferentiation after Cardiac Injury | 2,011 | 2011-11 | journal-article | Elsevier BV | Cell Stem Cell | 9 | 5 | 387-388 | 1934-5909 | null | Edward E. Morrisey | 1 | null | 12 | 8 | true | https://www.elsevier.com/tdm/userlicense/1.0/ | null | null | https://doi.org/10.1016/j.stem.2011.10.011 | null | null | null | en | n4EmbxwhoIT6ILoGV | an9HQtyrKzMvEcwRO |
10.1016/j.stem.2014.08.011 | 10.1016/j.stem.2014.08.011 | Quality Control: H2A.X Links to Better iPSCs | 2,014 | 2014-09 | journal-article | Elsevier BV | Cell Stem Cell | 15 | 3 | 259-260 | 1934-5909 | null | Yawei Gao, Shaorong Gao | 2 | null | 2 | 10 | true | https://www.elsevier.com/tdm/userlicense/1.0/ | null | null | https://doi.org/10.1016/j.stem.2014.08.011 | null | null | null | en | n4EmbxwhoIT6ILoGV | an9HQtyrKzMvEcwRO |
10.1016/j.stem.2009.08.021 | 10.1016/j.stem.2009.08.021 | Generation of Induced Pluripotent Stem Cells from Human Cord Blood | 2,009 | 2009-10 | journal-article | Elsevier BV | Cell Stem Cell | 5 | 4 | 434-441 | 1934-5909 | null | Alexandra Haase, Ruth Olmer, Kristin Schwanke, Stephanie Wunderlich, Sylvia Merkert, Christian Hess, Robert Zweigerdt, Ina Gruh, Johann Meyer, Stefan Wagner, Lars S. Maier, Dong Wook Han, Silke Glage, Konstantin Miller, Philipp Fischer, Hans R. Schöler, Ulrich Martin | 17 | null | 397 | 14 | true | https://www.elsevier.com/tdm/userlicense/1.0/ | null | null | https://doi.org/10.1016/j.stem.2009.08.021 | null | null | null | en | n4EmbxwhoIT6ILoGV | an9HQtyrKzMvEcwRO |
10.1016/j.stem.2020.06.002 | 10.1016/j.stem.2020.06.002 | Overcoming Autocrine FGF Signaling-Induced Heterogeneity in Naive Human ESCs Enables Modeling of Random X Chromosome Inactivation | 2,020 | 2020-09 | journal-article | Elsevier BV | Cell Stem Cell | 27 | 3 | 482-497.e4 | 1934-5909 | null | Chenrui An, Guihai Feng, Jixiang Zhang, Shiwei Cao, Ying Wang, Nannan Wang, Falong Lu, Qi Zhou, Haoyi Wang | 9 | null | 50 | 61 | true | https://www.elsevier.com/tdm/userlicense/1.0/ | National Key Research and Development Program of China Stem Cell and Translational Research | 10.13039/501100013290 | https://doi.org/10.1016/j.stem.2020.06.002 | null | null | null | en | n4EmbxwhoIT6ILoGV | an9HQtyrKzMvEcwRO |
10.1016/j.stem.2011.05.004 | 10.1016/j.stem.2011.05.004 | Functional Crosstalk between Bmi1 and MLL/Hoxa9 Axis in Establishment of Normal Hematopoietic and Leukemic Stem Cells | 2,011 | 2011-06 | journal-article | Elsevier BV | Cell Stem Cell | 8 | 6 | 649-662 | 1934-5909 | null | Lan-Lan Smith, Jenny Yeung, Bernd B. Zeisig, Nikolay Popov, Ivo Huijbers, Josephine Barnes, Amanda J. Wilson, Erdogan Taskesen, Ruud Delwel, Jesús Gil, Maarten Van Lohuizen, Chi Wai Eric So | 12 | null | 105 | 55 | true | https://www.elsevier.com/tdm/userlicense/1.0/ | null | null | https://doi.org/10.1016/j.stem.2011.05.004 | null | null | null | en | n4EmbxwhoIT6ILoGV | an9HQtyrKzMvEcwRO |
10.1016/j.stem.2020.06.010 | 10.1016/j.stem.2020.06.010 | Pathogen-Induced TLR4-TRIF Innate Immune Signaling in Hematopoietic Stem Cells Promotes Proliferation but Reduces Competitive Fitness | 2,020 | 2020-07 | journal-article | Elsevier BV | Cell Stem Cell | 27 | 1 | 177 | 1934-5909 | null | Hitoshi Takizawa, Kristin Fritsch, Larisa V. Kovtonyuk, Yasuyuki Saito, Chakradhar Yakkala, Kurt Jacobs, Akshay K. Ahuja, Massimo Lopes, Annika Hausmann, Wolf-Dietrich Hardt, Álvaro Gomariz, César Nombela-Arrieta, Markus G. Manz | 13 | null | 19 | 0 | true | https://www.elsevier.com/tdm/userlicense/1.0/ | null | null | https://doi.org/10.1016/j.stem.2020.06.010 | null | null | null | en | n4EmbxwhoIT6ILoGV | an9HQtyrKzMvEcwRO |
10.1016/j.stem.2011.02.002 | 10.1016/j.stem.2011.02.002 | Bone Marrow-Derived Cell Therapy Stimulates Endogenous Cardiomyocyte Progenitors and Promotes Cardiac Repair | 2,011 | 2011-04 | journal-article | Elsevier BV | Cell Stem Cell | 8 | 4 | 389-398 | 1934-5909 | null | Francesco S. Loffredo, Matthew L. Steinhauser, Joseph Gannon, Richard T. Lee | 4 | null | 334 | 30 | true | https://www.elsevier.com/tdm/userlicense/1.0/ | National Institutes of Health | 10.13039/100000002 | https://doi.org/10.1016/j.stem.2011.02.002 | null | null | null | en | n4EmbxwhoIT6ILoGV | an9HQtyrKzMvEcwRO |
10.1016/j.stem.2014.02.011 | 10.1016/j.stem.2014.02.011 | Ballroom Dancing with Stem Cells: Placement and Displacement in the Intestinal Crypt | 2,014 | 2014-03 | journal-article | Elsevier BV | Cell Stem Cell | 14 | 3 | 271-273 | 1934-5909 | null | Shahragim Tajbakhsh | 1 | null | 3 | 9 | true | https://www.elsevier.com/tdm/userlicense/1.0/ | null | null | https://doi.org/10.1016/j.stem.2014.02.011 | null | null | null | en | n4EmbxwhoIT6ILoGV | an9HQtyrKzMvEcwRO |
10.1016/j.stem.2014.03.011 | 10.1016/j.stem.2014.03.011 | Tailor Made Protein Synthesis for HSCs | 2,014 | 2014-04 | journal-article | Elsevier BV | Cell Stem Cell | 14 | 4 | 423-424 | 1934-5909 | null | Maria Barna, Davide Ruggero | 2 | null | 4 | 10 | true | https://www.elsevier.com/tdm/userlicense/1.0/ | null | null | https://doi.org/10.1016/j.stem.2014.03.011 | null | null | null | en | n4EmbxwhoIT6ILoGV | an9HQtyrKzMvEcwRO |
10.1016/j.stem.2014.07.013 | 10.1016/j.stem.2014.07.013 | Generation of Multipotent Induced Neural Crest by Direct Reprogramming of Human Postnatal Fibroblasts with a Single Transcription Factor | 2,014 | 2014-10 | journal-article | Elsevier BV | Cell Stem Cell | 15 | 4 | 497-506 | 1934-5909 | null | Yong Jun Kim, Hotae Lim, Zhe Li, Yohan Oh, Irina Kovlyagina, In Young Choi, Xinzhong Dong, Gabsang Lee | 8 | null | 128 | 29 | true | https://www.elsevier.com/tdm/userlicense/1.0/ | null | null | https://doi.org/10.1016/j.stem.2014.07.013 | null | null | null | en | n4EmbxwhoIT6ILoGV | an9HQtyrKzMvEcwRO |
10.1016/j.stem.2015.04.006 | 10.1016/j.stem.2015.04.006 | What Endothelial Cells from Patient iPSCs Can Tell Us about Aortic Valve Disease | 2,015 | 2015-05 | journal-article | Elsevier BV | Cell Stem Cell | 16 | 5 | 455-457 | 1934-5909 | null | Valeria V. Orlova, Christine L. Mummery | 2 | null | 4 | 10 | true | https://www.elsevier.com/tdm/userlicense/1.0/ | null | null | https://doi.org/10.1016/j.stem.2015.04.006 | null | null | null | en | n4EmbxwhoIT6ILoGV | an9HQtyrKzMvEcwRO |
10.1016/j.stem.2007.08.006 | 10.1016/j.stem.2007.08.006 | Human Parthenogenetic Embryo Stem Cells: Appreciating What You Have When You Have It | 2,007 | 2007-09 | journal-article | Elsevier BV | Cell Stem Cell | 1 | 3 | 243-244 | 1934-5909 | null | Paul A. De Sousa, Ian Wilmut | 2 | null | 13 | 8 | true | https://www.elsevier.com/tdm/userlicense/1.0/ | null | null | https://doi.org/10.1016/j.stem.2007.08.006 | null | null | null | en | n4EmbxwhoIT6ILoGV | an9HQtyrKzMvEcwRO |
10.1016/j.stem.2008.05.014 | 10.1016/j.stem.2008.05.014 | Puma: Mauling the Intestinal Crypt | 2,008 | 2008-06 | journal-article | Elsevier BV | Cell Stem Cell | 2 | 6 | 517-518 | 1934-5909 | null | Alan R. Clarke | 1 | null | 1 | 9 | true | https://www.elsevier.com/tdm/userlicense/1.0/ | null | null | https://doi.org/10.1016/j.stem.2008.05.014 | null | null | null | en | n4EmbxwhoIT6ILoGV | an9HQtyrKzMvEcwRO |
10.1016/j.stem.2008.01.011 | 10.1016/j.stem.2008.01.011 | Editors' Notes | 2,008 | 2008-02 | journal-article | Elsevier BV | Cell Stem Cell | 2 | 2 | xi | 1934-5909 | null | null | 0 | null | 0 | 0 | true | https://www.elsevier.com/tdm/userlicense/1.0/ | null | null | https://doi.org/10.1016/j.stem.2008.01.011 | null | null | null | en | n4EmbxwhoIT6ILoGV | an9HQtyrKzMvEcwRO |
10.1016/j.stem.2020.09.009 | 10.1016/j.stem.2020.09.009 | Defining the First Part of the Oncogenic KRAS Journey | 2,020 | 2020-10 | journal-article | Elsevier BV | Cell Stem Cell | 27 | 4 | 499-500 | 1934-5909 | null | Jihan K. Osborne, John D. Minna | 2 | null | 1 | 10 | true | https://www.elsevier.com/tdm/userlicense/1.0/ | Cancer Prevention and Research Institute of Texas, National Cancer Institute | 10.13039/100004917, 10.13039/100000054 | https://doi.org/10.1016/j.stem.2020.09.009 | null | null | null | en | n4EmbxwhoIT6ILoGV | an9HQtyrKzMvEcwRO |
10.1016/j.stem.2012.08.008 | 10.1016/j.stem.2012.08.008 | The Educated Person’s Video Guide to Stem Cells: The History, the Science, the Promise | 2,012 | 2012-09 | journal-article | Elsevier BV | Cell Stem Cell | 11 | 3 | 289-290 | 1934-5909 | null | Robin Anthony Elliott | 1 | null | 0 | 0 | true | https://www.elsevier.com/tdm/userlicense/1.0/ | null | null | https://doi.org/10.1016/j.stem.2012.08.008 | null | null | null | en | n4EmbxwhoIT6ILoGV | an9HQtyrKzMvEcwRO |
10.1016/j.stem.2013.08.008 | 10.1016/j.stem.2013.08.008 | Breaking the Canon: Indirect Regulation of Wnt Signaling in Mammary Stem Cells by MMP3 | 2,013 | 2013-09 | journal-article | Elsevier BV | Cell Stem Cell | 13 | 3 | 259-260 | 1934-5909 | null | Mark A. LaBarge | 1 | null | 4 | 10 | true | https://www.elsevier.com/tdm/userlicense/1.0/ | null | null | https://doi.org/10.1016/j.stem.2013.08.008 | null | null | null | en | n4EmbxwhoIT6ILoGV | an9HQtyrKzMvEcwRO |
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10.1016/j.stem.2019.04.008 | 10.1016/j.stem.2019.04.008 | Pluripotency on Lockdown after Deletion of Three Transcription Regulators | 2,019 | 2019-05 | journal-article | Elsevier BV | Cell Stem Cell | 24 | 5 | 681-683 | 1934-5909 | null | Jennifer A. Mitchell | 1 | null | 0 | 10 | true | https://www.elsevier.com/tdm/userlicense/1.0/ | null | null | https://doi.org/10.1016/j.stem.2019.04.008 | null | null | null | en | n4EmbxwhoIT6ILoGV | an9HQtyrKzMvEcwRO |
10.1016/j.stem.2013.06.006 | 10.1016/j.stem.2013.06.006 | Browsing (Epi)genomes: A Guide to Data Resources and Epigenome Browsers for Stem Cell Researchers | 2,013 | 2013-07 | journal-article | Elsevier BV | Cell Stem Cell | 13 | 1 | 14-21 | 1934-5909 | null | Rahul Karnik, Alexander Meissner | 2 | null | 19 | 41 | true | https://www.elsevier.com/tdm/userlicense/1.0/ | null | null | https://doi.org/10.1016/j.stem.2013.06.006 | null | null | null | en | n4EmbxwhoIT6ILoGV | an9HQtyrKzMvEcwRO |
10.1016/j.stem.2007.08.012 | 10.1016/j.stem.2007.08.012 | Cancer Stem Cells and Tumor Metastasis: First Steps into Uncharted Territory | 2,007 | 2007-09 | journal-article | Elsevier BV | Cell Stem Cell | 1 | 3 | 241-242 | 1934-5909 | null | Piero Dalerba, Michael F. Clarke | 2 | null | 148 | 6 | true | https://www.elsevier.com/tdm/userlicense/1.0/ | null | null | https://doi.org/10.1016/j.stem.2007.08.012 | null | null | null | en | n4EmbxwhoIT6ILoGV | an9HQtyrKzMvEcwRO |
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10.1038/d41586-022-00198-0 | 10.1038/d41586-022-00198-0 | Beyond academia: Planning the perfect exit strategy for a scientific career move | 2,022 | 2022-02-02 | journal-article | Springer Science and Business Media LLC | Nature | null | null | null | 0028-0836, 1476-4687 | null | Julie Gould | 1 | null | 0 | 0 | true | https://www.springer.com/tdm | null | null | https://doi.org/10.1038/d41586-022-00198-0 | https://www.nature.com/articles/d41586-022-00198-0.pdf | null | null | en | dqOqFWSEKD4Xc6Tuh | IDDjSnTd0zPxHVKiX |
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