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Fans can purchase tickets for various Cal State Fullerton athletic events by visiting FullertonTitans.com/Tickets. The Athletic Ticket Office can also be contacted by phone at 657-278-2783 or by email at athletictixs@fullerton.edu. The Ticket Office is located at the Titan House off of Gymnasium Drive at the eastern end of the Intramural Fields and is open from 10 am – 4 pm PT, Monday – Friday.
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Fans can keep up with the latest in Titan Athletics by following us on Facebook (Facebook/FullertonTitans), Twitter (@FullertonTitans) Instagram (@FullertonTitans) and Snapchat (FullertonTitans). In addition, the women's tennis team has its own Twitter (@FullertonWTEN) and Instagram accounts (@FullertonWTEN).
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Total Slides 1 : Active Index 1 : Last Slide Divs 5
-2
Thu Oct 17
TBA
Cal State Fullerton
vs. ITA Regionals
@ San Diego, Calif.
-2
Fri Oct 18
TBA
Cal State Fullerton
vs. ITA Regionals
@ San Diego, Calif.
-2
Sat Oct 19
TBA
Cal State Fullerton
vs. ITA Regionals
@ San Diego, Calif.
-2
Sun Oct 20
TBA
Cal State Fullerton
vs. ITA Regionals
@ San Diego, Calif.
-2
Sat Oct 26
9:00 AM
Tennis with the Titans
at Cal State Fullerton
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Formwork Accessories
NEVOSAFE with steel core
The NEVOSAFE® safety strip can be easily and quickly installed due to the integrated handle strip. It can be applied in horizontal and vertical positions and can be re-used. The NEVOSAFE® is available in high visible colours to increase visibility. NEVOSAFE®-PLUS is tested from a height to 3.0m up to 100 kg
Safety strip for protecting personnel on site from falls
NEVOSAFE®-PLUS safety strip with steel core
NoSaFE-PluS: protection tested from a height of 3.0m  up to 100kg
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Abbott's Investigational Interferon-Free Hepatitis C Treatment Regimen Achieved SVR12 (Observed Data) Rates in 99 Percent of Treatment-Naive and 93 Percent in Prior Null Responders for Genotype 1 Patients in Phase 2b Study
ABBOTT PARK Ill., Oct. 15, 2012 /PRNewswire/ -- Abbott (NYSE: ABT) today announced initial results from "Aviator," a phase 2b study of its interferon-free, investigational regimen for the treatment of hepatitis C (HCV). Initial results show sustained virological response at 12 weeks post treatment (SVR12) in 99 percent of treatment-naive (n=77) and 93 percent of null responders (n=41) for genotype 1 (GT1) HCV patients taking a combination of ABT-450/r, ABT-267, ABT-333 and ribavirin for 12 weeks, based on an observed data analysis.
Full results from the study will be presented at the Latebreaker Session of The Liver Meeting, the Annual Meeting of the American Association for the Study of Liver Disease (AASLD) in Boston, November 9-13. Abstracts are available at www.aasld.org.
The observed data analysis used in this abstract does not include six patients who had not yet reached post-treatment week 12 or had missing values (data points) at the time of the abstract submission. All virologic failures and safety discontinuations were included in the analysis.
"There is a significant unmet medical need for genotype 1, the most common form of HCV in the U.S. and Europe," said Kris Kowdley, M.D., director of the Liver Center of Excellence in the Digestive Disease Institute at Virginia Mason Medical Center, and Clinical Professor of Medicine at the University of Washington in Seattle. "Results from this phase 2b study suggest that sustained virological response can be achieved without interferon in a high proportion of genotype-1 patients, including patients who have not responded to previous treatment. This is exciting news as we continue to study treatment options for patients."
"Based on the promising results we've seen, Abbott has selected a triple direct acting antiviral regimen, with and without ribavirin for phase 3 development," said Scott Brun, M.D., divisional vice president, Infectious Disease Development, Abbott. "The ability to show sustained virological response in these patient populations, without the use of interferon, is extremely encouraging."
Study M11-652 (Aviator)
Kris Kowdley, et al.; Monday, November 12 (3:00-3:15 p.m. ET)
"A 12-Week Interferon-free Treatment Regimen with ABT-450/r, ABT-267, ABT-333 and Ribavirin Achieves SVR12 Rates (Observed Data) of 99% in Treatment-Naïve Patients and 93% in Prior Null Responders with HCV Genotype1 Infection"
The objective of this phase 2b study was to assess the safety, and efficacy of ABT-450/r (dosed 100/100 to 200/100mg QD), ABT-267 (25mg QD), ABT-333 (400mg BID) and ribavirin in non-cirrhotic treatment-naive patients and prior peg-interferon/ribavirin null responders for 8, 12 or 24 weeks.
Enrollment was open to GT1-infected patients regardless of IL28B host genotype and ribavirin dosing was weight-based.
The 12-week regimen of three direct acting antivirals plus ribavirin had the highest SVR12 rates among the 8 and 12 week arms. Results from the 12 week treatment groups containing three direct acting antivirals plus ribavirin are summarized in the chart below.
Treatment-naïve (N=79)
Null responders
(N=45)
BL HCV RNA (log10 IU/mL)
6.5+/-0.6
6.6+/-0.5
BL IL28B non-CC genotype
72%
96%
SVR4
78/79 (99%)
42/45 (93%)
OD SVR12
76/77 (99%)
38/41 (93%)
PTW12 data missing*
2
4
Breakthrough
0
3
Relapse
1
0