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A 10 mm polypoid lesion removed with cold snare polypectomy (G2, Ki67 PI 6%, R1) needed immediate subsequent surgical resection with lymphadenectomy (six of the sixteen lymph nodes that were removed were positive). | 3.275391 | 0.91748 | sec[2]/p[5] | en | 0.999997 | PMC11276314 | https://doi.org/10.3390/diagnostics14141484 |
Local recurrence occurred after 14 months in a 7 mm polypoid lesion removed with cold snare polypectomy (G1, Ki67 PI 2%, R1), which was then treated with cap-assisted EMR with a negative subsequent 50-month follow-up. | 3.253906 | 0.942871 | sec[2]/p[6] | en | 0.999999 | PMC11276314 | https://doi.org/10.3390/diagnostics14141484 |
One patient met the revised Chompret criteria for LFS because of a BC diagnosis at 28 years of age; that is, she met the criteria of juvenile breast cancer (<31 years). She was submitted to two molecular tests (a multigene out-of-pocket test and the specific one for p.R337H offered by the study). This patient was born ... | 3.84375 | 0.868652 | sec[2]/sec[2]/p[1] | en | 0.999997 | PMC11276326 | https://doi.org/10.3390/genes15070928 |
Case MOL1984-1 was diagnosed at the age of 10 years with reduced visual acuity, mild myopia (−3 D), and photophobia. His best corrected visual acuity (BCVA) at the age of 16 was 0.6/0.5 in the right and left eye, respectively, and OCT showed a retinoschisis pattern. He has no family history of visual deficiencies. An E... | 4 | 0.966797 | sec[2]/sec[4]/sec[0]/p[1] | en | 0.999997 | PMC11276581 | https://doi.org/10.3390/genes15070926 |
Case MOL2101-1 was diagnosed with a congenital retinal disease, including chorioretinal scars and retinoschisis. Visual acuity deteriorated and at the age of 11 reached 0.4 in the right eye and hand motion in the left eye with mild myopia (−3.5 diopters). Multiple electroretinography (ERG) examinations revealed non-pro... | 4.011719 | 0.945313 | sec[2]/sec[4]/sec[0]/p[2] | en | 0.999995 | PMC11276581 | https://doi.org/10.3390/genes15070926 |
Case MOL2246-1 was diagnosed with a congenital syndrome due to polydactyly (of both fingers and toes), nephrolithiasis, dysmorphism, hypotonia, developmental delay, patent foramen ovale in the heart, ocular gaze abnormality, and hypermetropia (+5.0 diopter). An ERG examination at the age of 7 months was performed under... | 4.066406 | 0.911133 | sec[2]/sec[4]/sec[2]/p[1] | en | 0.999998 | PMC11276581 | https://doi.org/10.3390/genes15070926 |
Case MOL2215-1 was diagnosed with molar tooth sign, dysplastic cerebellum, developmental delay, growth delay, high myopia (−17 diopters), and esotropia. His visual acuity at the age of 5 years was 6/45 both eyes and latent horizontal nystagmus was noted. ERG testing at the age of 11 years showed low rod (75% of normal)... | 3.966797 | 0.931641 | sec[2]/sec[4]/sec[2]/p[2] | en | 0.999998 | PMC11276581 | https://doi.org/10.3390/genes15070926 |
Several imagistic techniques are being used to detect myocardial abnormalities. However, in recent years, advanced echocardiographic techniques such as speckle tracking have become more popular for assessing the myocardium even in the intensive care unit . Because of its high sensitivity and low inter-observer variabil... | 4.101563 | 0.625 | sec[0]/p[1] | en | 0.999997 | 39057639 | https://doi.org/10.3390/jcdd11070219 |
Physical examination revealed low cardiac output and acute HF symptoms (pale skin with cold extremities, respiratory distress, tachycardia, a 4/6 holosystolic murmur at the left side of the sternal border, hepatomegaly). Laboratory tests indicated elevated serum creatinine levels, suggesting an acute pre-renal failure ... | 4.164063 | 0.833496 | sec[1]/p[1] | en | 0.999998 | 39057639 | https://doi.org/10.3390/jcdd11070219 |
Due to the critical state of the patient, preoperative inotropic treatment with Levosimendan was initiated along with anticoagulation with Enoxaparine. After stabilizing the patient, the surgical intervention was performed three days after the presentation. The LCA was re-implanted into the aorta using an aortic flap a... | 3.632813 | 0.975586 | sec[1]/p[3] | en | 0.999997 | 39057639 | https://doi.org/10.3390/jcdd11070219 |
In the postoperative period, the patient was hospitalized in the ICU for 63 days. In the first three days, sternum closure was delayed to stabilise the patient. Also, during the immediate postoperative care, the patient required aggressive treatment for HF, including the administration of various inotropes such as Adre... | 4.0625 | 0.959473 | sec[1]/p[4] | en | 0.999996 | 39057639 | https://doi.org/10.3390/jcdd11070219 |
In conclusion, despite clinical improvement and increased ejection fraction following surgical repair in ALCAPA patients, a short-term follow-up revealed that some regions of LV remained dysfunctional. This case highlights the importance of speckle-tracking echocardiography as a non-invasive tool for detecting myocardi... | 4.003906 | 0.69043 | sec[3]/p[0] | en | 0.999996 | 39057639 | https://doi.org/10.3390/jcdd11070219 |
Recent studies have demonstrated the benefits of performing complex percutaneous coronary interventions (PCIs) with the support of intracoronary imaging techniques, and international clinical guidelines recommend their use . Optical Coherence Tomography (OCT) uses near-infrared light to obtain in vivo images with high ... | 4.132813 | 0.819824 | sec[0]/p[0] | en | 0.999996 | 39057620 | https://doi.org/10.3390/jcdd11070200 |
A 60-year-old male, current smoker and dyslipidemic, was admitted to the emergency room due to chest pain. He referred to several episodes of chest pain on slight exertion in the last 48 h. His vitals revealed a temperature of 36.5 °C, a heart rate of 55 beats per minute, blood pressure of 130/78 mmHg and oxygen satura... | 3.929688 | 0.980957 | sec[1]/p[0] | en | 0.999998 | 39057620 | https://doi.org/10.3390/jcdd11070200 |
The patient was informed of the findings and the various treatment options. It was decided to perform PCI in the same procedure guided by intracoronary OCT imaging to assess the anatomy, take measurements and evaluate the possible involvement of the distal left main coronary artery (LMA) as well as the ostium of the LA... | 3.248047 | 0.931641 | sec[1]/p[1] | en | 0.999999 | 39057620 | https://doi.org/10.3390/jcdd11070200 |
Intravenous unfractionated heparin (100 U per kg) was administered. The LMA was catheterized with a 6F 4 EBU guiding catheter, then a Sion guidewire was advanced to the distal segment of the LAD, and a Sion blue guidewire was advanced to the distal segment of the CX. Subsequently, the ostial stenosis of the LAD was dil... | 3.982422 | 0.507813 | sec[1]/p[2] | en | 0.999998 | 39057620 | https://doi.org/10.3390/jcdd11070200 |
Immediately after completing the injection, the patient experienced ventricular fibrillation (VF) , requiring external defibrillation with 360 J, which successfully restored sinus rhythm. The patient recovered promptly. Based on the OCT images obtained from the prior OCT, we proceed with the deployment of a 3.5/18 mm s... | 3.964844 | 0.959473 | sec[1]/p[3] | en | 0.999997 | 39057620 | https://doi.org/10.3390/jcdd11070200 |
A new OCT, injecting 15 mL of contrast (4 mL/s for 4 s), revealed adequate apposition and expansion of the LMA stent, with no evidence of distal or proximal dissection, and it also confirmed the correct opening of the stent struts at the ostium of the CX . The patient did not experience any further ventricular arrhythm... | 3.689453 | 0.934082 | sec[1]/p[4] | en | 0.999997 | 39057620 | https://doi.org/10.3390/jcdd11070200 |
Therefore, we believe that the primary cause of the arrhythmia in our patient was myocardial ischemia, which may be attributed to the significant volume of contrast utilized during the second pullback. The posterior R-on-T phenomenon was a key factor in precipitating the subsequent VF. | 3.517578 | 0.824219 | sec[2]/p[6] | en | 0.999997 | 39057620 | https://doi.org/10.3390/jcdd11070200 |
To the best of our knowledge, this is the first reported case of VF during OCT preceded by widening of the QRS complex and ST elevation, suggesting myocardial ischemia as the mechanism favoring VF. With high probability, the amount of contrast administered in the second pullback was the determinant of VF. For this reas... | 4.082031 | 0.935059 | sec[3]/p[0] | en | 0.999996 | 39057620 | https://doi.org/10.3390/jcdd11070200 |
We report a preterm male newborn with a predisposition to WS, who presented with multiple complications at birth. Despite early respiratory and feeding challenges, he stabilized with no neurological issues. Genetic testing confirmed WS and multisystem anomalies were managed effectively. The infant’s recovery was suppor... | 3.296875 | 0.986816 | sec[0]/p[1] | en | 0.999996 | PMC11277181 | https://doi.org/10.7759/cureus.63206 |
A newborn male with a strong genetic predisposition to WS was born prematurely at 35 weeks of gestation via urgent cesarean section due to complications, including meconium aspiration, gestational hypertension, and maternal diabetes mellitus. He weighed 3400 grams at birth. The delivery required immediate resuscitative... | 3.740234 | 0.98291 | sec[1]/p[0] | en | 0.999995 | PMC11277181 | https://doi.org/10.7759/cureus.63206 |
Upon admission to the neonatal intensive care unit (NICU), the infant exhibited symptoms consistent with transient tachypnea of the newborn (TTN). The initial assessment revealed moderate respiratory distress characterized by mild subcostal and intercostal retractions, with an initial oxygen saturation of 88% on room a... | 3.652344 | 0.979492 | sec[1]/p[1] | en | 0.999997 | PMC11277181 | https://doi.org/10.7759/cureus.63206 |
Treatment began with supplemental oxygen via nasal cannula, but due to worsening respiratory status, including increased work of breathing and intermittent desaturation, it was intensified to endotracheal intubation and mechanical ventilation. The highest ventilator settings recorded were a peak inspiratory pressure (P... | 3.869141 | 0.63623 | sec[1]/p[2] | en | 0.999997 | PMC11277181 | https://doi.org/10.7759/cureus.63206 |
Despite standard ventilatory support, the infant continued to struggle with hypoxemia. This led to a brief period of high-frequency oscillatory (HFO) ventilation before a return to conventional methods. Alongside surfactant therapy, the medical team made frequent adjustments to the ventilatory settings, closely monitor... | 3.474609 | 0.942383 | sec[1]/p[4] | en | 0.999998 | PMC11277181 | https://doi.org/10.7759/cureus.63206 |
Sepsis management involved treating elevated inflammatory markers with broad-spectrum antibiotics (Table 1 ), despite negative blood cultures. The antibiotics were initially started at admission to the NICU due to the generalized sickness level of the baby, even though the initial absolute neutrophil count (ANC) was no... | 3.824219 | 0.960938 | sec[1]/p[5] | en | 0.999996 | PMC11277181 | https://doi.org/10.7759/cureus.63206 |
On the third day after birth, the infant’s hyperbilirubinemia reached its highest level, with total serum bilirubin (TSB) levels peaking at approximately 10-12 mg/dL (171-205 µmol/L). Effective management with phototherapy was initiated, as this value exceeded the cut-off for a premature infant (35-37 weeks gestation).... | 4.035156 | 0.90625 | sec[1]/p[6] | en | 0.999997 | PMC11277181 | https://doi.org/10.7759/cureus.63206 |
The cardiac assessment uncovered a spectrum of anomalies. Notably, there was a patent foramen ovale with a left-to-right shunt and left ventricular hypertrophy of the non-obstructive variety. Additionally, a moderate tricuspid valve regurgitation was measured at 60 mmHg, alongside a small muscular ventricular septal de... | 4.152344 | 0.937012 | sec[1]/p[7] | en | 0.999997 | PMC11277181 | https://doi.org/10.7759/cureus.63206 |
The abdominal ultrasound brought to light a series of renal abnormalities. Among these was a left-sided multicystic dysplastic kidney, accompanied by bilateral hydronephrosis. The left ureter appeared tortuous and dilated, extending all the way to the ureterovesical junction, which was associated with a grade 4 vesicou... | 4.011719 | 0.952148 | sec[1]/p[8] | en | 0.999997 | PMC11277181 | https://doi.org/10.7759/cureus.63206 |
During the patient's hospitalization, multiple clinical signs raised suspicions of WS, as the patient exhibited several distinctive facial features. These included dystopia canthorum, telecanthus, a striking white forelock, and a notably broad nasal root and bridge. A thorough examination revealed no signs of organomeg... | 3.166016 | 0.986816 | sec[1]/p[10] | en | 0.999996 | PMC11277181 | https://doi.org/10.7759/cureus.63206 |
Upon conducting an auditory brainstem response test, the infant was diagnosed with bilateral sensorineural hearing loss. The infant exhibited neither abnormal movements nor signs of seizures. Additional neurological examinations and brain ultrasound scans were conducted, all of which returned normal findings with no ev... | 3.115234 | 0.977051 | sec[1]/p[11] | en | 0.999996 | PMC11277181 | https://doi.org/10.7759/cureus.63206 |
Finally, we highlight the intricate management of a newborn diagnosed with WS type 1, emphasizing the necessity for a thorough and interdisciplinary approach to complex genetic conditions. The infant exhibited hallmark symptoms of WS, along with unanticipated renal and cardiac abnormalities, which called for meticulous... | 3.660156 | 0.819824 | sec[3]/p[0] | en | 0.999997 | PMC11277181 | https://doi.org/10.7759/cureus.63206 |
Prompt and effective treatment of critical conditions, including transient tachypnea and hyperbilirubinemia, as well as specialized management of renal and cardiac complications, highlighted the significance of prompt and ongoing care. Furthermore, this case accentuated the vital importance of addressing early hearing ... | 3.398438 | 0.956543 | sec[3]/p[1] | en | 0.999995 | PMC11277181 | https://doi.org/10.7759/cureus.63206 |
This case study describes a 64-year-old man with left-sided hemiparesis and a failed surgical treatment of a pertrochanteric fracture of the proximal femur in the spastic limb. He was admitted to the Department of Rehabilitation and Orthopedics in December 2022 for diagnostic evaluation and treatment planning after fiv... | 3.263672 | 0.989258 | sec[1]/sec[0]/p[0] | en | 0.999998 | PMC11277479 | https://doi.org/10.3390/jcm13144023 |
Following a hemorrhagic stroke in 2005, the patient underwent extensive rehabilitation, focusing on locomotion and upper limb manipulation. Following recovery, he was able to walk independently using a hand cane. His Barthel scale score was 85, indicating slight disability and independence in daily activities, although... | 3.701172 | 0.971191 | sec[1]/sec[2]/p[0] | en | 0.999997 | PMC11277479 | https://doi.org/10.3390/jcm13144023 |
In July 2022, the patient came to the emergency room due to severe pain in the left hemiparetic limb and the inability to bear weight on it after a fall from his own height. During the examination, an X-ray revealed a pertrochanteric fracture of the left lower limb. The second day after the fracture, surgery was perfor... | 3.076172 | 0.990234 | sec[1]/sec[3]/p[0] | en | 0.999997 | PMC11277479 | https://doi.org/10.3390/jcm13144023 |
The first stage of treatment, performed in January 2023, involved the removal of the failed fixation and the use of an absorbable calcium sulfate antibiotic carrier with Gentamicin to fill bone defects. This was followed by comprehensive perioperative care, including antibiotic therapy, antithrombotic prophylaxis, and ... | 3.160156 | 0.898926 | sec[1]/sec[4]/p[1] | en | 0.999998 | PMC11277479 | https://doi.org/10.3390/jcm13144023 |
Before the botulinum treatment, the muscle tension of the paretic limb was assessed as 3 according to the Ashworth scale (mm. gastrocnemius, soleus, posterior tibialis, and adductors). There was also a significant limitation of mobility in the hip joint (flexion–adduction contracture 20 degrees), knee joint (flexion co... | 3.894531 | 0.917969 | sec[1]/sec[4]/p[4] | en | 0.999997 | PMC11277479 | https://doi.org/10.3390/jcm13144023 |
After the final stage of the treatment, which involved the insertion of a complete bipolar snap-on prosthesis and adductor muscle tenotomy, the patient was able to walk short distances (about 30 m) and climb the stairs with support . His Barthel scale score improved to 60, although his Tinetti scale score remained low ... | 3.492188 | 0.983887 | sec[1]/sec[4]/p[9] | en | 0.999997 | PMC11277479 | https://doi.org/10.3390/jcm13144023 |
Our patient scored 10 on the Tinetti scale following a stroke, indicating a high fall risk and underscoring the need for targeted rehabilitation to improve balance and coordination . The Barthel scale, used to assess patient independence in daily activities, showed a score of 60, indicating moderate disability and part... | 3.335938 | 0.942871 | sec[2]/p[1] | en | 0.999996 | PMC11277479 | https://doi.org/10.3390/jcm13144023 |
The research also indicates that patients with hemiplegia experience longer hospital stays and more frequent postoperative complications, highlighting the need for specialized care protocols. Choosing the appropriate surgical approach, such as the direct anterior approach, and selecting the optimal type of artificial h... | 4.195313 | 0.523926 | sec[3]/p[1] | en | 0.999998 | PMC11277479 | https://doi.org/10.3390/jcm13144023 |
A 70-year-old active smoker without any prior surgical history nor a known family history for aortic diseases presented to the emergency department with a 2-week history of intermittent chest pain, hoarseness, and dry cough. Computed tomography (CT) angiography revealed a 13-cm TAA with left-side pleural effusion . The... | 3.951172 | 0.974121 | sec[0]/p[0] | en | 0.999995 | PMC11277743 | https://doi.org/10.1016/j.jvscit.2024.101550 |
An 8-mm Advanta V12 (Atrium) was deployed in the LCCA using the chimney graft technique. Subsequently, a steerable sheet was used to access the LSA, and an ISLF was performed with a 1.7-mm Turbo-Elite Laser Catheter (Philips), with an 0.018 wire passing into the ascending aorta through the ISLF fenestration. The fenest... | 3.935547 | 0.949219 | sec[0]/p[3] | en | 0.999997 | PMC11277743 | https://doi.org/10.1016/j.jvscit.2024.101550 |
The first follow-up CT angiography 2 months postoperatively showed a significant stenosis of the LSA bridging stent graft . The patient was scheduled for a reintervention. Imaging at time of reintervention showed a fully fractured LSA stent . Successful cannulation of the LSA was performed through left brachial access,... | 3.855469 | 0.974121 | sec[0]/p[4] | en | 0.999997 | PMC11277743 | https://doi.org/10.1016/j.jvscit.2024.101550 |
In this paper, we describe the first case of bridging stent graft fracture after ISLF during TEVAR. According to existing literature, balloon expandable stents are more rigid and straight, which makes them more susceptible to collapse and fractures when the external pressure is high. 11 , 12 The non-reinforced characte... | 4.199219 | 0.546875 | sec[1]/p[2] | en | 0.999997 | PMC11277743 | https://doi.org/10.1016/j.jvscit.2024.101550 |
Considering the unexpected complication that occurred after the ISLF during this emergent TEVAR, an individualized follow-up plan was utilized for this patient. The first CT scan was performed 2 months after the reintervention, with a yearly CT scan being planned. Any target vessel instability seen during the follow-up... | 3.4375 | 0.853516 | sec[1]/p[4] | en | 0.999996 | PMC11277743 | https://doi.org/10.1016/j.jvscit.2024.101550 |
A 7-month-old male Rottweiler was referred for consultation because of severe swelling on the left side of the jaw, with a suspected jaw tumor. Clinical examination revealed no abnormalities in the aforementioned lymph glands and no soreness on palpation. Intraoral examination on the left side revealed severe asymmetry... | 4.015625 | 0.978027 | sec[1]/sec[1]/p[0] | en | 0.999997 | PMC11277777 | https://doi.org/10.3390/life14070879 |
A 3-year-old German Shepherd dog was referred with a suspected periapical abscess of a tooth on the right side. The medical history of the pet client reported that the dog had been treated for chronic rhinitis for 6 months. On clinical examination, tooth 104 (right maxillary fang) was observed to be missing, with no wo... | 3.982422 | 0.978027 | sec[1]/sec[1]/p[1] | en | 0.999997 | PMC11277777 | https://doi.org/10.3390/life14070879 |
A 10-month-old American Staffordshire Terrier dog was referred for an orthodontic consultation due to abnormal alignment of the maxillary teeth and the resulting bite injuries. Clinical examination revealed three properly aligned incisors on the right side and four incisors (including one tooth with a double crown) on ... | 3.994141 | 0.975098 | sec[1]/sec[1]/p[2] | en | 0.999996 | PMC11277777 | https://doi.org/10.3390/life14070879 |
The bone cavity, after such a large open extraction, was 3.0 cm × 4.2 cm; so, the decision was made to implant polymeric hydroxyapatite with curdlan soaked in 0.9% NaCl into the areas of bone loss. The flap was sutured with 4-0 monofilament single sutures. A follow-up radiograph was taken 28 days after surgery. On clin... | 3.078125 | 0.978516 | sec[1]/sec[1]/p[3] | en | 0.999996 | PMC11277777 | https://doi.org/10.3390/life14070879 |
A 14-month-old female Cane Corso was referred for dental diagnosis due to the absence of tooth 204 and periodic swelling of the left suborbital region. The dog had been treated ophthalmologically for 4 months for recurrent conjunctivitis of the left eye and increased epiphora. Ophthalmologic examination revealed obstru... | 4.042969 | 0.972656 | sec[1]/sec[1]/p[4] | en | 0.999996 | PMC11277777 | https://doi.org/10.3390/life14070879 |
Case 1 : A 33-year-old male dentist, born in 1979, had been suffering from very early detumescence since adolescence. He was impatient to wait for other options and resorted to penile implantation to treat his ED. Thus, he underwent penile venous coil embolization (CE) to treat veno-occlusive dysfunction (VOD) due to a... | 3.720703 | 0.984863 | sec[1]/sec[0]/p[0] | en | 0.999995 | PMC11278194 | https://doi.org/10.3390/life14070911 |
Case 2 : A 42-year-old housebuilder, born in 1972, had suffered from ED resulting from VOD since 1994 and received penile venous CE in 2000. He experienced some improvement in erection quality from 2000 to 2003, but then ED recurred, with a subsequent physician declining his request for CE in 2005. Refractory ED prompt... | 3.230469 | 0.988281 | sec[1]/sec[0]/p[1] | en | 0.999996 | PMC11278194 | https://doi.org/10.3390/life14070911 |
A contrast CT scan confirmed two coils installed in the left and right pulmonary arterial trees. The coils were tightly adhesive to the vessel wall; a coil had traversed the right ventricle wall and lodged within the pericardium . He received PVS of the excessive drainage veins with an uneventful postoperative course. ... | 3.683594 | 0.983398 | sec[1]/sec[0]/p[2] | en | 0.999999 | PMC11278194 | https://doi.org/10.3390/life14070911 |
Case 3 : A 31-year-old banker, born in 1985, had suffered from ED resulting from VOD since age 23. He then underwent his first penile venous CE in the northern hemisphere in 2010, with no improvement in erectile function. Table 1 summarizes three CE courses at different medical school-affiliated hospitals. Acute chest ... | 3.949219 | 0.982422 | sec[1]/sec[0]/p[3] | en | 0.999996 | PMC11278194 | https://doi.org/10.3390/life14070911 |
Case 4 and 5: Two university students, born in 1992 and 1993, respectively, had suffered from ED resulting from VOD since the ages of 23 and 21. They underwent their first penile venous CE in the northern hemisphere in 2015 and 2017 with no improvement in erectile function. In 2017 and 2018, intractable ED prompted the... | 3.244141 | 0.989746 | sec[1]/sec[0]/p[4] | en | 0.999997 | PMC11278194 | https://doi.org/10.3390/life14070911 |
Anomalous arteriovenous shunts between meningeal arteries and dural venous sinuses or cortical veins are known as dural arteriovenous fistulas (DAVFs). This abnormality accounts for 10–15% of all intracranial arteriovenous malformations . Ethmoid branches of the ophthalmic artery provide eDAVFs, which make up about 2–3... | 4.285156 | 0.853516 | sec[0]/p[0] | en | 0.999997 | PMC11278917 | https://doi.org/10.3390/medicina60071128 |
In December 2022, a 60-year-old man with a high fever and Lemierre syndrome diagnosis was admitted to Chung Shan University Hospital. After the patient’s admission, a head and neck computer tomography (CT) scan and a brain magnetic resonance angiography were performed to assess the cause of the fever. These tests unint... | 3.962891 | 0.975586 | sec[1]/p[1] | en | 0.999998 | PMC11278917 | https://doi.org/10.3390/medicina60071128 |
In April 2024, a 71-year-old man was found with a right side eDAVF incidentally in Linkou Chang Gung Memorial Hospital. An initial brain CTA showed a right frontal base vascular lesion. The right superficial temporal artery and the right ethmoidal branches of the right ophthalmic artery feeded blood into the eDAVF. The... | 3.720703 | 0.972656 | sec[1]/p[3] | en | 0.999998 | PMC11278917 | https://doi.org/10.3390/medicina60071128 |
A 47-year-old non-smoking man presented at the clinic of periodontics at the University Hospital of Lille, Lille, France, on January 24th, 2022, with a chief complaint of a generalized gingival overgrowth. His medical history revealed a diagnosis of hypertension nine months ago which was treated with a combination of p... | 3.775391 | 0.982422 | sec[1]/p[1] | en | 0.999996 | PMC11279205 | https://doi.org/10.7759/cureus.63214 |
Despite reporting brushing twice a day, the patient exhibited poor oral hygiene. The complete periodontal examination revealed generalized pseudo-pockets (probing depth from 4 to 9 mm) and a bleeding on probing (BOP) score of 100%. Radiographs revealed generalized moderate bone loss on both maxillary and mandibular arc... | 3.216797 | 0.983887 | sec[1]/p[2] | en | 0.999996 | PMC11279205 | https://doi.org/10.7759/cureus.63214 |
A 58-year-old male patient presented at the Department of Periodontics at Louis Mourier’s University Hospital, Paris, France, on March 1st, 2023, with a chief complaint of gingival overgrowth associated with spontaneous gum bleeding, gingival pain, halitosis, and self-reported tooth mobility. The medical history includ... | 3.876953 | 0.982422 | sec[1]/p[5] | en | 0.999995 | PMC11279205 | https://doi.org/10.7759/cureus.63214 |
Step 1 involved referring the patients to their physician for a switch in medication suspected to be causing gingival enlargement. Additionally, comprehensive oral hygiene instructions were provided, along with a full-mouth supragingival instrumentation using standard ultrasonic tips (Acteon Satelec, Mérignac, France).... | 3.054688 | 0.885742 | sec[1]/p[11] | en | 0.999994 | PMC11279205 | https://doi.org/10.7759/cureus.63214 |
In Step 3 for the non-responding sites (sites with or without residual bleeding pocket associated with gingival overgrowth), retreatment was carried out through non-surgical repeated subgingival instrumentation only. In Case 1, systemic antibiotics were administered as adjunctive therapy due to the high number of non-r... | 3.511719 | 0.872559 | sec[1]/p[15] | en | 0.999997 | PMC11279205 | https://doi.org/10.7759/cureus.63214 |
One patient presented in this case report (Case 1) received systemic antibiotics as an adjunct to periodontal treatment. Even though the clinical situation improved after a thorough hygiene motivation phase and several sessions of supra and subgingival instrumentation, it was not completely successful as many bleeding ... | 4.105469 | 0.935059 | sec[2]/p[3] | en | 0.999998 | PMC11279205 | https://doi.org/10.7759/cureus.63214 |
This report highlights two successful cases demonstrating the complete resolution of severe DIGE, primarily influenced by amlodipine. The resolution was achieved through a non-surgical approach only, involving drug substitution and repeated sessions of mechanical instrumentation. Not all patients may respond to this tr... | 3.925781 | 0.957031 | sec[3]/p[0] | en | 0.999997 | PMC11279205 | https://doi.org/10.7759/cureus.63214 |
A 52-year-old Caucasian woman had a history of stage IV (presence of solitary liver metastasis, which disappeared after neoadjuvant chemotherapy) triple-negative breast cancer in remission for over five years . She presented with CIPN in her feet and neuropathic pain around her right axilla and shoulder. She had previo... | 3.896484 | 0.982422 | sec[1]/p[0] | en | 0.999996 | PMC11279394 | https://doi.org/10.3390/ph17070834 |
At baseline (BL), the patient’s PBMC count, CRP count, and absolute monocyte count were moderately elevated, but her lymphocyte percentage was normal ( Table 1 ). The woman was moderately active and her painDETECT was consistent with a neuropathic type of pain ( Table 2 ). | 3.017578 | 0.890625 | sec[1]/p[2] | en | 0.999996 | PMC11279394 | https://doi.org/10.3390/ph17070834 |
This case report provides initial but holistic evidence supporting complementary approaches for addressing CIPN in cancer survivors. It suggests that clinically meaningful improvements in CIPN symptoms, quality of life, and functional status can be achieved through combining the oral administration of 300 mg/day of CBD... | 4.09375 | 0.908691 | sec[3]/p[0] | en | 0.999997 | PMC11279394 | https://doi.org/10.3390/ph17070834 |
General treatment guidelines for RA include nonsteroidal anti-inflammatory drugs, glucocorticoids, disease-modifying antirheumatic drugs, and biologics. Tofacitinib, a Janus kinase (JAK) inhibitor that was Food and Drug Administration approved for RA in 2012, has been shown to be relatively well tolerated. 3 Tofacitini... | 3.876953 | 0.877441 | sec[0]/p[1] | en | 0.999996 | PMC11280084 | https://doi.org/10.1016/j.jdcr.2024.05.033 |
A 29-year-old woman with history of seronegative RA presented with severe pain and morning stiffness particularly of the wrists and ankles thus limiting her activities of daily living. Her symptoms began at age 8, and both her father and sister are similarly affected. Her medication trials include intralesional steroid... | 3.755859 | 0.98584 | sec[1]/p[0] | en | 0.999998 | PMC11280084 | https://doi.org/10.1016/j.jdcr.2024.05.033 |
Complete blood count, comprehensive metabolic panel, antinuclear antibody were within normal limits. C-reactive protein and erythrocyte sedimentation rate were elevated to 1.23 and 53, respectively. She was negative for Lyme disease. Rheumatoid factor was <14 and anticyclic citrullinated peptide was <20. Imaging showed... | 3.777344 | 0.952148 | sec[1]/p[1] | en | 0.999996 | PMC11280084 | https://doi.org/10.1016/j.jdcr.2024.05.033 |
Because of the severity of her joint pain, and resistance to multiple other treatments, she was started on a trial of tofacitinib 5 mg twice daily and hydroxychloroquine. With treatment, the patient had improvement in her chronic rheumatoid nodules with resolution of active skin lesions. Because of a change in her insu... | 3.507813 | 0.98584 | sec[1]/p[2] | en | 0.999998 | PMC11280084 | https://doi.org/10.1016/j.jdcr.2024.05.033 |
Since restarting tofacitinib, the patient was noted to have improvements in chronic rheumatoid nodules as well as a reduction in flares and open ulcers. Skin examination showed numerous scarred and atrophic plaques and nodules over the cheeks, lateral aspect of the arms, elbows, forearms, hands with emphasis at extenso... | 3.505859 | 0.98291 | sec[1]/p[3] | en | 0.999996 | PMC11280084 | https://doi.org/10.1016/j.jdcr.2024.05.033 |
A 7-month-old male child from Malappuram District, Kerala, the third child of non-consanguineous parents, presented with persistent pneumonia for the last two months. His growth parameters and developmental milestones were normal. The child received two doses of OPV (birth dose and at 20 weeks) ( Table 1 ). Investigati... | 3.712891 | 0.976563 | sec[2]/sec[0]/p[0] | en | 0.999997 | PMC11281642 | https://doi.org/10.3390/vaccines12070759 |
The child underwent a haploidentical hematopoietic stem cell transplantation with TCR alpha beta depleted peripheral blood stem cells from his father. Two days later, he developed a fever and breathlessness, followed by watery diarrhea. His chest X-ray was suggestive of right upper lobe collapse with pneumonitis. Four ... | 3.978516 | 0.981445 | sec[2]/sec[5]/p[0] | en | 0.999996 | PMC11281642 | https://doi.org/10.3390/vaccines12070759 |
Overall, the management of ameloblastoma depends on eradicating the affected tissue, along with clean reconstruction of the remaining parts, which makes it a challenging goal to achieve. This highlights the importance of individualized surgical planning and treatment based on both patient factors and tumor factors . Am... | 3.601563 | 0.939941 | sec[0]/p[3] | en | 0.999997 | PMC11281802 | https://doi.org/10.7759/cureus.63233 |
A 17-year-old male patient was referred to the Ear, Nose, and Throat Department at National Guard Hospital, Jeddah, Saudi Arabia, in 2006, complaining of a painless right facial swelling that had lasted for two months. The swelling was gradually increasing in size, and there were no reports of weight loss, loss of appe... | 3.810547 | 0.986328 | sec[1]/p[1] | en | 0.999998 | PMC11281802 | https://doi.org/10.7759/cureus.63233 |
After two years, in 2008, the patient complained of painless swelling of the right maxilla. The swelling was compressing the eye globe, leading to reduced visual acuity. Upon evaluation, a smooth-surfaced, non-tender cystic mass was identified above the right lower orbital rim, with normal extra-ocular muscle movements... | 3.689453 | 0.98877 | sec[1]/p[3] | en | 0.999996 | PMC11281802 | https://doi.org/10.7759/cureus.63233 |
In 2011, the patient presented with a recurrence of ameloblastoma, which was evidenced by a swelling in the right maxilla persisting for a duration of eight months. There was no reported history of nasal obstruction, visual impairments, feeding difficulties, trismus, or chronic ailments. Upon physical examination, the ... | 4.09375 | 0.973145 | sec[1]/p[5] | en | 0.999997 | PMC11281802 | https://doi.org/10.7759/cureus.63233 |
Maxillary ameloblastoma is a rare form of odontogenic epithelial tumor, with 80% of ameloblastomas occurring in the mandible. We reviewed similar case reports from the literature. According to these reports, this subtype typically presents as a painless mass, likely due to the anatomical location of the maxilla. The tu... | 3.923828 | 0.442627 | sec[2]/p[0] | en | 0.999997 | PMC11281802 | https://doi.org/10.7759/cureus.63233 |
We report a rare case where a urinoma was developed because of urine leakage from bilateral ureteric injuries that occurred after an abdominal hysterectomy. The urinoma was initially misdiagnosed as an intraperitoneal hematoma. Appropriate radiological investigations enhanced the accurate diagnosis of urinoma and led t... | 3.615234 | 0.983398 | sec[0]/p[5] | en | 0.999997 | PMC11281829 | https://doi.org/10.7759/cureus.63235 |
A 41-year-old woman, P2, presented to the emergency department (ED) for adults with abdominal pain and bloating. She had undergone an abdominal hysterectomy for large fibroids six days earlier in a private hospital. Her post-operative period in the primary hospital was unremarkable, and she was discharged home on the t... | 3.025391 | 0.990723 | sec[1]/p[1] | en | 0.999997 | PMC11281829 | https://doi.org/10.7759/cureus.63235 |
The results of the laboratory tests showed a mild leukocytosis (13.1 × 10^3/uL), with a slight increase in alanine transaminase (ALT = 72 U/L) and aspartate transaminase (AST = 72 U/L). Her hemoglobin was 10 g/dL, C-reactive protein (CRP) was 5 mg/L, and the results of the renal function tests were in the normal range.... | 3.625 | 0.979492 | sec[1]/p[5] | en | 0.999997 | PMC11281829 | https://doi.org/10.7759/cureus.63235 |
Laboratory results revealed a decrease in hemoglobin from 10 to 8.8 gm/dL, an increased total leukocyte count of 14.3 × 10^3/uL, and an elevated CRP of 89 mg/L. Serum creatinine was 248 umol/L (normal range, 50-98 umol/L) with an elevated prothrombin time of 18.1 seconds (normal range, 9.4-12.5 s) and an activated part... | 3.890625 | 0.696289 | sec[1]/p[9] | en | 0.999998 | PMC11281829 | https://doi.org/10.7759/cureus.63235 |
Based on her clinical findings, laboratory results, and previous sonography results, pelvic hematoma and sepsis were suspected. A repeat ultrasound was performed . An intra-abdominal fluid collection with internal echoes and septa was seen in the pelvic cavity close to the uterine bed, measuring approximately 15.3 × 11... | 3.925781 | 0.977051 | sec[1]/p[11] | en | 0.999997 | PMC11281829 | https://doi.org/10.7759/cureus.63235 |
With CT urogram, diagnosis of left ureteric injury was confirmed. So, the initial plan for laparotomy was abandoned. Two units of packed red blood cells and two units of fresh frozen plasma were transfused. She had a right percutaneous nephrostomy with left ureteric antegrade double-J stenting and CT-guided drainage of... | 3.503906 | 0.986328 | sec[1]/p[13] | en | 0.999998 | PMC11281829 | https://doi.org/10.7759/cureus.63235 |
In cases where urine leaks require more extensive treatment, a combination of antibiotic therapy, minimally invasive procedures, and catheterization can be used to effectively manage the condition. This approach typically involves the placement of percutaneous urinoma drainage catheters, percutaneous nephrostomy cathet... | 3.986328 | 0.625977 | sec[2]/p[8] | en | 0.999996 | PMC11281829 | https://doi.org/10.7759/cureus.63235 |
This unusual case serves as a reminder to remain vigilant in identifying both intra-operative and post-operative urinary tract trauma, emphasizing the importance of timely diagnosis and repair to prevent adverse outcomes. | 3.082031 | 0.966309 | sec[2]/p[16] | en | 0.999997 | PMC11281829 | https://doi.org/10.7759/cureus.63235 |
A 77-year-old man had undergone pancreatoduodenectomy 1 year earlier for cholangiocarcinoma. At his current presentation, he was admitted to our hospital for acute pancreatitis due to PJS. First, EUS-guided pancreatic duct drainage using a plastic stent was performed. Then 2 weeks later, PJS treatment was attempted. Fi... | 3.861328 | 0.980469 | sec[0]/p[1] | en | 0.999997 | PMC11281845 | https://doi.org/10.1055/a-2357-2274 |
A 19-year-old nulliparous woman presented in the emergency room (ER) with an intentional polysubstance overdose of unknown quantities of ibuprofen, acetaminophen, and dextromethorphan/pseudoephedrine in an attempt to end her life. There was no evidence of hepatitis, acidosis, or other toxidrome. She was thoroughly eval... | 3.416016 | 0.987793 | sec[1]/p[0] | en | 0.999995 | PMC11281859 | https://doi.org/10.7759/cureus.63238 |
She reported becoming more argumentative and emotionally labile, and various episodes of uncontrollable and erratic behavior for the last six months. Her gynecological history included irregular menstrual cycles occurring once or twice a year since her menarche at 11 years old. She tried birth control pills for her irr... | 3.673828 | 0.97998 | sec[1]/p[1] | en | 0.999995 | PMC11281859 | https://doi.org/10.7759/cureus.63238 |
She maintained a diary of her symptoms and found a clear cyclical pattern related to her menstruation. Her mood symptoms increased dramatically in the premenstrual period, followed by a sense of relief after periods started. The Daily Record of Severity of Problems (DRSP) score, which is used for diagnosis and assessme... | 4.046875 | 0.912109 | sec[1]/p[3] | en | 0.999995 | PMC11281859 | https://doi.org/10.7759/cureus.63238 |
Pregnancy was excluded prior to starting treatment. As the detailed evaluation of the patient was being carried out and the patient reported a family history of bipolar disorder, she was initiated on 25 mg lamotrigine for mood stabilization instead of a selective serotonin reuptake inhibitor (SSRI) as the latter can pr... | 3.1875 | 0.977539 | sec[1]/p[5] | en | 0.999996 | PMC11281859 | https://doi.org/10.7759/cureus.63238 |
On subsequent outpatient follow-up visits, our patient expressed great emotional relief, and "stability" in her own words, following her diagnosis of PMDD. She finally felt "listened to" and felt motivated to start working towards her dream of getting an education degree and becoming a middle school English teacher. He... | 3.1875 | 0.986816 | sec[1]/p[6] | en | 0.999997 | PMC11281859 | https://doi.org/10.7759/cureus.63238 |
Our patient fulfilled the PMDD criteria of having at least 5 out of 11 stipulated symptoms identified in the DSM-5, one of which must include mood, behavioral, or physical symptoms with substantial stress or functional impairment. Confirming symptoms by prospective patient mood charting for at least two menstrual cycle... | 3.988281 | 0.85791 | sec[2]/p[2] | en | 0.999996 | PMC11281859 | https://doi.org/10.7759/cureus.63238 |
Management options for PMDD include psychotropic agents (SSRIs) and ovulation suppression agents (combined oral contraceptive pill (COCP) or gonadotropin-releasing hormone (GnRH) agonists). The recommended doses of SSRIs include sertraline 50-100 mg, fluoxetine 20 mg, escitalopram 10-20 mg, and paroxetine 10-20 mg. Our... | 3.808594 | 0.843262 | sec[2]/p[6] | en | 0.999998 | PMC11281859 | https://doi.org/10.7759/cureus.63238 |
Similarly, a 45-year-old Caucasian female diagnosed with bipolar disorder with psychotic features, PMDD, panic disorder, and repeated occurrence of suicide attempts and self-harming behavior reported limited gains through standard medicinal treatment and showed dramatic clinical improvement after introduction of lifest... | 3.816406 | 0.913574 | sec[2]/p[14] | en | 0.999998 | PMC11281859 | https://doi.org/10.7759/cureus.63238 |
In this report, we present a case of a middle-aged male who presented with chest pain and breathlessness and was found to have multiple congenital cardiac conditions. The report details the subsequent evaluation and surgical correction performed. | 3.054688 | 0.989258 | sec[0]/p[1] | en | 0.999997 | PMC11281883 | https://doi.org/10.7759/cureus.63194 |
A 41-year-old male presented to a tertiary care hospital in the cardiac outpatient department (OPD) with complaints of chest pain, breathlessness (New York Heart Association (NYHA) grade 3), and an on-and-off headache for a month. The patient was diagnosed with polycythemia (Hb 22 g/dL) one and a half months ago. He ha... | 3.554688 | 0.988281 | sec[1]/p[0] | en | 0.999997 | PMC11281883 | https://doi.org/10.7759/cureus.63194 |
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