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2018-04-03T04:06:09.115Z | 1996-06-01T00:00:00.000Z | 24962770 | s2ag/train | Two-phase helical CT for pancreatic tumors: pancreatic versus hepatic phase enhancement of tumor, pancreas, and vascular structures.
PURPOSE
To quantitatively evaluate and validate a two-phase helical computed tomographic (CT) protocol for evaluation of pancreatic tumors.
MATERIALS AND METHODS
Twenty-seven patients ... | v2 |
2017-04-09T03:33:00.369Z | 1997-10-01T00:00:00.000Z | 4381220 | s2ag/train | Relations between functional, inflammatory, and degenerative parameters during adjuvant arthritis in rats.
We assessed the time-course of adjuvant arthritis (AA) in Lewis rats, using biotelemetry to monitor the rat's spontaneous locomotor activity and body temperature, and studied the evolution of the arthritic index,... | v2 |
2018-04-03T04:38:57.652Z | 2008-01-01T00:00:00.000Z | 20555820 | s2ag/train | Klotho Expression in Epithelial Ovarian Cancer and its Association with Insulin-Like Growth Factors and Disease Progression
Klotho is an anti-aging hormone and is able to suppress the action of IGFs. High IGF activities are associated with cancer risk and tumor progression. Klotho's role in cancer is unknown. To evalu... | v2 |
2018-04-03T02:56:42.007Z | 2008-10-01T00:00:00.000Z | 23645770 | s2ag/train | Enhanced plasma levels of LIGHT in patients with acute atherothrombotic stroke
Objectives – As a member of the tumor necrosis factor superfamily (TNFSF), LIGHT (TNFSF14) was recently found to be associated with platelets and released upon activation. Increased plasma levels of LIGHT have been reported in patients wit... | v2 |
2018-04-03T02:18:52.966Z | 1989-02-01T00:00:00.000Z | 3299070 | s2ag/train | Effects of gonadotropin-releasing hormone and its agonists on prolactin secretion from normal and tumorous pituitary cells.
Previous studies on the effect of gonadotropin-releasing hormone (LHRH) agonist on prolactin (PRL) secretion from normal and tumorous pituitary cells have not been conclusive as to the mechanism ... | v2 |
2021-11-12T06:17:17.257Z | 2021-01-01T00:00:00.000Z | 243987220 | s2ag/train | Dilatation and curettage in endometrial cancer. What is the correlation with hysterectomy histology? A 14 years retrospective cohort study.
PURPOSE
The aim of the present study is to evaluate the concordance between preoperative endometrial sampling histopathology performed by conventional dilatation and curettage (D&... | v2 |
2018-04-03T01:00:10.489Z | 2017-04-01T00:00:00.000Z | 21405870 | s2ag/train | [A rarely isolated bacterium in microbiology laboratories: Streptococcus uberis].
Streptococcus uberis is a gram-positive bacterium that is mostly responsible for mastitis in cattle. The bacterium rarely has been associated with human infections. Conventional phenotyphic methods can be inadequate for the identificatio... | v2 |
2018-04-03T05:46:34.608Z | 2014-06-01T00:00:00.000Z | 44376470 | s2ag/train | Type VII collagen and squamous cell carcinoma
Recessive dystrophic epidermolysis bullosa (RDEB), an inherited blistering disease, is caused by mutations in COL7A1, the gene encoding type VII collagen (Col7), which is the main component of anchoring fibrils. Affected individuals have decreased or undetectable Col7 with... | v2 |
2018-04-03T05:18:30.803Z | 2001-09-01T00:00:00.000Z | 42394110 | s2ag/train | 8-Prenylnaringenin, the phytoestrogen in hops and beer, upregulates the function of the E-cadherin/catenin complex in human mammary carcinoma cells.
The E-cadherin/catenin complex is a powerful invasion suppressor in epithelial cells. It is expressed in the human MCF-7 breast cancer cell line family, but functionally ... | v2 |
2022-05-09T13:16:02.130Z | 2022-01-01T00:00:00.000Z | 248562460 | s2ag/train | Biosynthesis and characterization of silver nanoparticles prepared using seeds of Sisymbrium irio and evaluation of their antifungal and cytotoxic activities
Abstract Recent studies have shown that green synthesis of silver nanoparticles (AgNPs) and their application in the control of phytopathogenic fungi is a burgeo... | v2 |
2018-04-03T01:38:31.906Z | 1998-11-25T00:00:00.000Z | 46782210 | s2ag/train | Comparison of Rigid and Flexible Transbronchial Needle Aspiration in the Staging of Bronchogenic Carcinoma
In staging bronchogenic carcinoma by transbronchial needle aspiration (TBNA), rigid histology needles are generally preferred to flexible cytology needles owing to the widespread opinion that rigid needles have h... | v2 |
2022-02-27T06:22:48.443Z | 2022-01-01T00:00:00.000Z | 247130110 | s2ag/train | Impact of Medicaid Expansion on the Diagnosis, Treatment, and Outcomes of Stage II and III Rectal Cancer Patients.
BACKGROUND
Insurance status has been associated with disparities in stage at cancer diagnosis. We examined how Medicaid expansion (ME) impacted diagnoses, surgical treatment, use of neoadjuvant therapies ... | v2 |
2020-12-10T09:07:56.074Z | 2020-12-03T00:00:00.000Z | 229438610 | s2ag/train | Panitumumab-Induced Paronychia: A Case Report and a Brief Review of the Literature
Panitumumab is a recombinant, fully humanized IgG2 monoclonal antibody targeting the epidermal growth factor receptor (EGFR). Panitumumab is indicated for patients with metastatic colorectal cancer with progressive refractory disease. T... | v2 |
2022-05-16T19:08:18.272Z | 2022-05-16T00:00:00.000Z | 248809210 | s2ag/train | Outcome of complex surgical resection and reconstruction for rare thoracic cancers: the clinical value of a predictive score
Background. Complex surgical resection and reconstruction for rare thoracic cancers (RTCs) represent a major challenge, given their very low frequency, extreme variability of presentation, multi... | v2 |
2018-04-03T06:17:59.042Z | 1998-10-01T00:00:00.000Z | 46316510 | s2ag/train | Cell surface density of p185(c-erbB-2) determines susceptibility to anti-p185(c-erbB-2)-ricin A chain (RTA) immunotoxin therapy alone and in combination with anti-p170(EGFR)-RTA in ovarian cancer cells.
Approximately 30% of ovarian and breast cancers overexpress p185(c-erbB-2) with as many as 10(6) receptors/cell. Nor... | v2 |
2021-07-27T00:06:05.087Z | 2021-05-20T00:00:00.000Z | 236398910 | s2ag/train | Heterogeneity between core needle biopsy and synchronous axillary lymph node metastases in early breast cancer patients: Comparison of HER2, estrogen and progesterone receptor expression profiles during primary treatment regime.
e12565 Background: Therapeutic decisions for the primary treatment of breast cancer is com... | v2 |
2018-04-03T04:20:19.014Z | 1997-10-25T00:00:00.000Z | 38637470 | s2ag/train | A pharmacophore model of tautomycin, an inhibitor of protein phosphatases 1 and 2A.
Over the last decade there has been a growing realization that phosphatases are extremely important in cellular and organismal functions1}. Tautomycin, an inhibitor of protein phosphatases (PP) 1 and 2A, was isolated from a culture bro... | v2 |
2018-04-03T02:05:32.630Z | 1996-08-01T00:00:00.000Z | 20957320 | s2ag/train | Rectal cancer: the influence of type of operation on local recurrence and survival.
OBJECTIVE
To assess the results of standardised total mesorectal excision of rectal cancer with particular reference to local recurrence and survival.
DESIGN
Prospective open study.
SETTING
Central hospital, Norway.
MAIN OUTCOME ... | v2 |
2018-04-03T02:42:16.770Z | 2004-05-07T00:00:00.000Z | 34794920 | s2ag/train | [Study on relationship of fucosyltransferase gene types in breast cancer with metastasis and prognosis].
OBJECTIVE
To assess the association of five types of fucosyltransferase gene (Fuc-T), the important biosynthesis gene of sialylated carbohydrate antigens (Sialyl Lewis A, Sialyl Lewis X), with metastasis and progno... | v2 |
2018-04-03T02:25:16.514Z | 2016-12-01T00:00:00.000Z | 23323860 | s2ag/train | Implementing the Risk of Ovarian Malignancy Algorithm Adding Obesity as a Predictive Factor.
AIM
To evaluate whether obesity represents a risk factor for the onset of ovarian cancer.
PATIENTS AND METHODS
One hundred and sixty-three patients with a body mass index (BMI) >30 kg/m2 (group 1) and 130 women with a BMI of... | v2 |
2018-10-07T08:21:21.258Z | 2018-08-29T00:00:00.000Z | 53065960 | s2ag/train | Assessing Waste Taxation: an Empirical Study in a Cge Multi-Pollutant Framework
Economic theory states that incineration and landfill taxes can be a good policy to reduce environmental impacts of these activities by reducing their importance and associated pollutants, while stimulating reuse and recycling of materials... | v2 |
2018-04-03T01:02:39.781Z | 2011-05-01T00:00:00.000Z | 27759810 | s2ag/train | [Sublobar resection for non-small cell lung cancer in Iceland].
INTRODUCTION
A sublobar resection is performed on patients with non-small cell lung cancer (NSCLC) who are not candidates for a lobectomy due to reduced pulmonary function or comorbid disease. The aim of this study was to investigate the outcomes of these... | v2 |
2018-04-03T05:39:26.451Z | 1988-01-01T00:00:00.000Z | 43708810 | s2ag/train | Von Recklinghausen neurofibromatosis with carcinoid tumor and submucous leiomyomas of the duodenum.
We report on a 63-year-old man with von Recklinghausen neurofibromatosis who developed a carcinoid tumor in the periampullary region and multiple small-sized leiomyomas in the duodenal wall. A high prevalence of gastroi... | v2 |
2017-04-08T08:45:43.730Z | 1985-01-01T00:00:00.000Z | 5518810 | s2ag/train | Appearance of systemic amyloidosis in a chronic hemodialysis patient.
Dr. D. Hillion, Department of Nephrology, Centre Hospitalier Intercommunal de Poissy, 10, rue du Champ Gaillard, F-78303 Poissy (France) Dear Sir, Since 1977, amyloid deposits in the transverse carpal ligament of patients on regular dialysis treatme... | v2 |
2018-04-03T04:12:44.189Z | 2013-06-11T00:00:00.000Z | 38077610 | s2ag/train | Survival in patients with oral and maxillofacial diffuse large B-cell lymphoma.
The purpose of this study was to determine the survival and prognostic factors of patients with diffuse large B-cell lymphoma (DLBCL) of the oral cavity and maxillofacial region. Retrospectively, the clinical records of patients with a pri... | v2 |
2020-04-23T06:30:17.914Z | 2006-01-01T00:00:00.000Z | 216064920 | s2ag/train | Paper MEAN DOSE TO LYMPHOCYTES DURING RADIOTHERAPY TREATMENTS
-Using a probabilistic model with parameters from four radiotherapy protocols used in Mexican hospitals for the treatment of cervical cancer, we have calculated the distribution of dose to cells in peripheral blood of patients. Values of the mean dose to th... | v2 |
2018-01-24T17:25:33.048Z | 2009-05-20T00:00:00.000Z | 27019820 | s2ag/train | Neoadjuvant platinum-based chemotherapy (CT) for triple-negative locally advanced breast cancer (LABC): Retrospective analysis of 125 patients.
625 Background: Triple-negative breast cancer (TNBC), defined by lack of estrogen receptor, progesterone receptor, and human epidermal growth factor receptor 2, accounts for 1... | v2 |
2019-05-04T13:05:49.373Z | 2015-01-01T00:00:00.000Z | 143538470 | s2ag/train | A Rough Road Map to Reflexivity in Qualitative Research into Emotions
In qualitative research into emotions, researchers and participants share emotion-laden interactions. Few demonstrate how the analytic value of emotions may be harnessed. In this article we provide an account of our emotional experiences conducting ... | v2 |
2021-08-03T00:04:16.886Z | 2021-01-01T00:00:00.000Z | 236763870 | s2ag/train | Regional nodal irradiation in the setting of sentinel node biopsy
: The need for axillary lymph node dissection (ALND) in patients with invasive breast cancer (IBC) has been a topic of great debate in the last decade. The role of axillary management in patients with sentinel lymph node biopsy (SLNB) negative or microm... | v2 |
2019-04-03T13:10:56.223Z | 2018-09-01T00:00:00.000Z | 92438310 | s2ag/train | Abstract B28: Targeted inhibition of EGFR and glutaminase induces metabolic crisis in EGFR-mutant lung cancer
Cancer cells exhibit increased use of nutrients, including glucose and glutamine, to support the bioenergetic and biosynthetic demands of proliferation. We tested the small-molecule inhibitor of glutaminase CB... | v2 |
2018-04-03T00:10:48.817Z | 2009-10-01T00:00:00.000Z | 205966310 | s2ag/train | Discussion. Free flap breast reconstruction in advanced age: is it safe?
T average life expectancy of the U.S. population continues to increase and with it there is a corresponding increase in the incidence of disease directly correlated with increasing age, such as prostate cancer in males and breast cancer in female... | v2 |
2018-04-03T02:31:29.442Z | 1985-05-01T00:00:00.000Z | 34052010 | s2ag/train | Role of Computed Tomography and Mediastinoscopy in Preoperative Staging of Lung Carcinoma
One hundred fifty-three patients with bronchogenic carcinoma were evaluated prospectively by CT and mediastinoscopy. Nodes larger than 5 mm were considered potentially metastatic. All results were correlated with surgical finding... | v2 |
2018-04-03T02:47:23.051Z | 2006-11-01T00:00:00.000Z | 24598170 | s2ag/train | Clinical value of planar and tomographic dual-isotope scintigraphy using 99mTc-methylene diphosphonate and 131I in patients with thyroid cancer
Purpose131I whole-body scintigraphy is a highly sensitive method for the detection of differentiated thyroid tumours and metastases. However, a lack of anatomical landmarks an... | v2 |
2019-01-22T22:20:13.082Z | 2018-12-01T00:00:00.000Z | 58584170 | s2ag/train | A fluid future for liquid biopsies
O ncologists have dreamed of them for years: noninvasive alternatives to tissue biopsies that can quickly identify tumors by the cells, DNA, or other cell components that they shed into patients’ blood. Now, several promising studies and a wave of prototypes suggest that such tests m... | v2 |
2018-04-03T00:43:22.365Z | 1983-07-01T00:00:00.000Z | 26339710 | s2ag/train | Neonatal jaundice and developmental defects
trauma, and are rarely associated with biliary malignancy. The most common type is the cholecystoduodenal fistula, and this accounted for 76% of cases in the Mayo Clinic study of 424 patients with fistulae.I Cholangitis is frequently found with the cholecystocolic type.':' C... | v2 |
2018-04-03T01:44:51.575Z | 2012-06-20T00:00:00.000Z | 30806710 | s2ag/train | Pathology and prognosis in pseudomyxoma peritonei: a review of 274 cases
Aims The classification of abdominal mucinous neoplasia is a controversial area. In 2010, WHO published a classification which divides pseudomyxoma peritonei (PMP) into low and high grades. The aim of the authors was to correlate this classificat... | v2 |
2022-08-11T06:16:08.814Z | 2022-08-09T00:00:00.000Z | 251469920 | s2ag/train | Physical Activity in Stage III Colon Cancer: CALGB/SWOG 80702 (Alliance).
PURPOSE
To determine the specific types, durations, and intensities of recreational physical activity associated with the greatest improvements in disease-free survival (DFS) of patients with colon cancer.
METHODS
We conducted a prospective co... | v2 |
2019-11-15T14:09:26.988Z | 2019-11-13T00:00:00.000Z | 208017820 | s2ag/train | Expression and Clinical Significance of POLR1D in Colorectal Cancer
Purpose: RNA polymerase I subunit D (POLR1D) is involved in the synthesis of ribosomal RNA precursors and small RNAs, but its mechanism in the development and progression of colorectal cancer (CRC) remains ambiguous. Thus, this research aimed to inves... | v2 |
2018-04-03T00:31:46.739Z | 2009-02-12T00:00:00.000Z | 12709710 | s2ag/train | Addressing bone loss in the cancer survivor.
Osteoporosis, the most common late effect of cancer treatment in the US, occurs with greater frequency among cancer survivors than the general population. Survivors of breast cancer, prostate cancer, and childhood leukemia are at particularly high risk for changes in bone m... | v2 |
2018-04-03T02:35:12.270Z | 2002-02-01T00:00:00.000Z | 25563400 | s2ag/train | [Possibilities of magnetic resonance tomography in pancreatic cancer diagnosis].
There was conducted examination of 27 patients with pancreatic cancer using clinico-laboratory and instrumental methods: ultrasonic investigation, computeric tomography (CT), magnetic-resonance tomography (MRT). MRT was uninformative when... | v2 |
2018-04-03T01:56:36.829Z | 2002-06-01T00:00:00.000Z | 26088960 | s2ag/train | In vivo induction of proinflammatory cytokines in mouse tissue by Porphyromonas gingivalis and Actinobacillus actinomycetemcomitans.
Periodontitis is a chronic inflammatory disease initiated by a multitude of bacteria. Persistent infection leads to generation of various inflammatory mediators, resulting in tissue dest... | v2 |
2018-04-03T01:34:43.486Z | 2003-01-01T00:00:00.000Z | 29895260 | s2ag/train | Cure of Barrett's carcinoma by ifosfamide chemotherapy.
The prognosis of patients with oesophageal cancer is poor, with an overall 5-year survival rate below 15%. The best chance for cure of patients with oesophageal cancer is surgical resection. However, more than 50% of patients have inoperable disease and can only ... | v2 |
2018-04-03T04:47:13.923Z | 1988-08-01T00:00:00.000Z | 40319210 | s2ag/train | Recurrent rectal cancer: diagnosis with MR imaging versus CT.
During an 18-month period, a prospective study comparing the findings at computed tomography (CT) and magnetic resonance (MR) imaging was conducted on 35 patients who satisfied the following criteria: prior surgery for rectal cancer (11 curative resections,... | v2 |
2017-04-14T09:59:22.712Z | 1987-08-15T00:00:00.000Z | 9206310 | s2ag/train | Characterization of cell lines derived from xenografts of childhood rhabdomyosarcoma.
Three human rhabdomyosarcoma cell lines (Rh10, Rh18, and Rh28) have been established from three independently derived xenografts. These lines have been characterized as mesenchymal in origin (reactivity to desmin and vimentin antibod... | v2 |
2016-10-26T03:31:20.546Z | 2011-10-03T00:00:00.000Z | 27085150 | s2ag/train | Insight into the heterogeneity of breast cancer through next-generation sequencing.
Rapid and sophisticated improvements in molecular analysis have allowed us to sequence whole human genomes as well as cancer genomes, and the findings suggest that we may be approaching the ability to individualize the diagnosis and tr... | v2 |
2018-04-03T05:02:42.769Z | 1990-06-01T00:00:00.000Z | 41326950 | s2ag/train | [Immunoglobulin and T-cell receptor gene rearrangements in patients with autoimmune diseases].
Immunoglobulin-(Ig-) and T-cell-receptor-(TcR-)gene rearrangements were investigated in peripheral blood lymphocytes (PBL) of patients with various autoimmune disorders. In patients with SLE there was no predominant Ig- or T... | v2 |
2018-04-03T03:54:01.301Z | 1997-04-01T00:00:00.000Z | 36908850 | s2ag/train | Endoscopic ultrasound-guided real-time fine-needle aspiration biopsy of the pancreas in cancer patients with pancreatic lesions.
BACKGROUND
Endoscopic ultrasound (EUS) is an important new tool in the staging of pancreatic malignancies. Using new curved linear-array instruments, real-time fine-needle aspiration biopsy ... | v2 |
2017-11-08T00:50:00.635Z | 1999-10-01T00:00:00.000Z | 27411000 | s2ag/train | A Lot of Heartburn, a Little Cancer
ABSTRACTThis is a well-designed, population-based, case-control, epidemiological study to determine if individuals with symptoms of gastroesophageal reflux disease are at increased risk for the development of adenocarcinoma of the esophagus and gastric cardia. Over a 3-yr period, fr... | v2 |
2018-04-03T04:37:15.716Z | 1993-03-09T00:00:00.000Z | 39726050 | s2ag/train | [Compliance problems and behavioral medicine implications in the drug therapy of pain].
Many patients, even cancer patients do not take their medication at all or at the prescribed dose showing thus a form of noncompliance. Reasons for this are manyfold and differ from patient to patient. They may undergo dynamic chan... | v2 |
2018-04-03T02:46:30.442Z | 2011-09-01T00:00:00.000Z | 21769310 | s2ag/train | Inhibition of cyclin-dependent kinase phosphorylation of FOXO1 and prostate cancer cell growth by a peptide derived from FOXO1.
Increasing evidence suggests that FOXO1 possesses a tumor suppressor function. Inactivation of FOXO1 has been documented in many types of human cancer, and restoring the activity of FOXO1 hol... | v2 |
2018-04-03T05:51:09.237Z | 2006-08-15T00:00:00.000Z | 44681260 | s2ag/train | Production of VEGF165 by Ewing's sarcoma cells induces vasculogenesis and the incorporation of CD34+ stem cells into the expanding tumor vasculature
The Ewing's sarcoma cell line TC71 overexpresses vascular endothelial growth factor isoform 165 (VEGF165), a potent proangiogenic molecule that induces endothelial cell p... | v2 |
2018-04-03T05:32:57.038Z | 2013-01-01T00:00:00.000Z | 43317560 | s2ag/train | Stratospheric ozone, global warming, and the principle of unintended consequences--an ongoing science and policy success story.
One of the important technical achievements to protect human health and wellbeing in the 20th century was the widespread development and application of refrigeration for food preservation and... | v2 |
2017-06-10T20:58:05.576Z | 2005-01-01T00:00:00.000Z | 10730560 | s2ag/train | Expression of bone morphogenetic proteins in human metastatic prostate and breast cancer.
AIM
To analyze the expression of bone morphogenetic proteins (BMPs) in prostate and breast cancers with established metastasis in bone, where prostate cancer causes osteoblastic metastases, and breast cancer osteolytic metastases... | v2 |
2017-04-27T08:35:35.871Z | 2010-01-01T00:00:00.000Z | 133210 | s2ag/train | Cervical cancer screening programme in Primorsko-Goranska County, Croatia--the results of the pilot study.
The opportunistic cervical cancer screening has been conducted in Croatia since its introduction in the 1960s, in the context of a high quality gynaecological cytology with a long tradition and a wide network of ... | v2 |
2019-08-18T20:01:11.334Z | 2011-10-01T00:00:00.000Z | 202650910 | s2ag/train | Title Page / Table of Contents
s HORMONE RESEARCH IN PÆDIATRICS Basel • Freiburg • Paris • London • New York • New Delhi • Bangkok • Beijing • Tokyo • Kuala Lumpur • Singapore • Sydney HRP_2011_076_S02_tivo.indd I 01.07.2011 11:02:11 This publication was sponsored by Eli Lilly and Company Ferring Pharmaceuticals Ipsen... | v2 |
2021-10-26T06:16:47.008Z | 2021-10-23T00:00:00.000Z | 239766710 | s2ag/train | Identification of lipid metabolism-related genes as prognostic indicators in papillary thyroid cancer.
Lipid metabolism plays important roles not only in the structural basis and energy supply of healthy cells but also in the oncogenesis and progression of cancers. In this study, we investigated the prognostic value o... | v2 |
2018-04-03T00:10:57.317Z | 2011-11-23T00:00:00.000Z | 206678660 | s2ag/train | Rapid Cancer Detection by Topically Spraying a γ-Glutamyltranspeptidase–Activated Fluorescent Probe
A spirocyclic-caged, small-molecule imaging probe fluoresces upon cleavage by a cancer-specific enzyme and can be used during surgical or endoscopic tumor removal procedures. No Tumor Left Behind Although quick action w... | v2 |
2017-10-18T11:55:08.051Z | 2016-10-25T00:00:00.000Z | 9551960 | s2ag/train | Curcumin as Natural Bioactive compound of Medicinal Plant Curcuma longa to combat against different Diseases
Plants are gifts by nature as they gives alot of benefits to human race. Medicinal herb Curcuma longa has a long history of use in medicine due to its anti-inflammatory, antioxidant, analgesic, antimicrobial an... | v2 |
2018-04-03T02:42:55.142Z | 2013-05-01T00:00:00.000Z | 25567860 | s2ag/train | [Comparison of antiemesis effects of granisetron, aprepitant and dexamethasone to palonosetron, aprepitant and dexamethasone in treatment of high-emetic risk chemotherapy-induced nausea and vomiting - a retrospective study for efficacy and safety in a single institute].
Nausea and vomiting are among the most problemat... | v2 |
2017-04-07T16:57:07.468Z | 2014-02-01T00:00:00.000Z | 16169410 | s2ag/train | Novel EXT1 mutation identified in a pedigree with hereditary multiple exostoses.
Hereditary multiple exostoses (HME) is an autosomal dominant bone disorder characterized by the presence of multiple benign cartilage-capped tumors. EXT1 located on chromosome 8q23-q24 and EXT2 located on 11p11-p12 are the main disease-ca... | v2 |
2018-04-03T06:17:59.042Z | 2012-09-01T00:00:00.000Z | 23482660 | s2ag/train | The development of IL‐17/IFN‐γ‐double producing CTLs from Tc17 cells is driven by epigenetic suppression of Socs3 gene promoter
The plasticity of T lymphocytes induced by epigenetic modifications of gene promoters may play a pivotal role in controlling their effector functions, which are sometimes causally associated ... | v2 |
2021-04-18T05:25:02.920Z | 2020-12-01T00:00:00.000Z | 233285450 | s2ag/train | The Evidence Supporting a Systematic Approach to the Care of the Injured Patient:From Prevention to Rehabilitation
INTRODUCTION Trauma is the leading cause of death for individuals under 45 years of age in the Western world and remains the fourth leading cause of death for all ages combined (1,2,3,4). Approximately 0.... | v2 |
2019-10-19T13:34:38.808Z | 2019-10-18T00:00:00.000Z | 204772200 | s2ag/train | Multidimensional imaging provides evidence for down-regulation of T cell effector function by MDSC in human cancer tissue
Intratumoral physical engagement of T cells with immunosuppressive neutrophils is associated with reduced effector function. Interior tumor views Previous studies indicate that a high frequency of ... | v2 |
2017-04-19T07:38:41.397Z | 2015-01-01T00:00:00.000Z | 16031000 | s2ag/train | Comparison of outcomes of locoregionally advanced oropharyngeal and non-oropharyngeal squamous cell carcinoma over two decades.
BACKGROUND
Human papillomavirus (HPV) has emerged as a causative agent and positive prognostic factor for oropharyngeal (OP) head and neck squamous cell cancer (HNSCC). This prompts inquiry i... | v2 |
2018-04-03T05:16:29.650Z | 2005-01-01T00:00:00.000Z | 42067700 | s2ag/train | Tumor necrosis factor-alpha-induced protein 1 and immunity to hepatitis B virus.
AIM
To compare the gene expression profile in a pair of HBV-infected twins.
METHODS
The gene expression profile was compared in a pair of HBV-infected twins.
RESULTS
The twins displayed different disease outcomes. One acquired natural... | v2 |
2017-09-26T14:58:42.200Z | 1998-01-01T00:00:00.000Z | 11252500 | s2ag/train | Considerations in making a diagnosis
Dipl. ABVP a continuing challenge for clinicians. Comparative Medical and Vetennary Services Los Angeles County Department of Health Services Clinical epidemiology, biostatistics, Downey, California 90242 and clinical decision-making are “new” tools that help practitioners make dia... | v2 |
2017-08-15T05:12:53.345Z | 1996-06-01T00:00:00.000Z | 24629900 | s2ag/train | Human osteoclast-like cells selectively recognize laminin isoforms, an event that induces migration and activates Ca2+ mediated signals.
Osteoclast precursors are chemotactically attracted to sites of bone resorption via migration pathways that include transendothelial crossing in blood capillaries. Transendothelial m... | v2 |
2018-04-03T00:11:50.776Z | 2016-03-01T00:00:00.000Z | 10501900 | s2ag/train | Yeast-Derived Particulate β-Glucan Treatment Subverts the Suppression of Myeloid-Derived Suppressor Cells (MDSC) by Inducing Polymorphonuclear MDSC Apoptosis and Monocytic MDSC Differentiation to APC in Cancer
Myeloid-derived suppressor cells (MDSC) are a heterogeneous population of immature myeloid cells that promote... | v2 |
2021-05-05T00:09:38.864Z | 2021-03-11T00:00:00.000Z | 233712500 | s2ag/train | Salvage Lymphadenectomy as a Treatment of Prostate Cancer Recurrence
Biochemical recurrence (BCR) occurs up to 40% of men who had radical prostatectomy for localized prostate cancer. Regional nodes are usually involved in these cases. Salvage lymphadenectomy (sLND) has been advocated in patients with 'node-only' metas... | v2 |
2018-04-03T01:33:43.113Z | 1998-05-01T00:00:00.000Z | 21761460 | s2ag/train | Renal tubular reabsorption of phosphate is positively related to the extent of bone metastatic load in patients with prostate cancer.
Osteolytic metastases are often associated with decreased renal tubular reabsorption of phosphate. There is, however, no specific data on phosphate metabolism in metastases from prostat... | v2 |
2018-04-03T02:13:11.077Z | 1989-01-01T00:00:00.000Z | 20716810 | s2ag/train | [Increased expression of IGF-2 in tumor tissue of nephroblastoma].
The incidence of nephroblastoma is increased in a number of syndromes with abnormal growth pattern. Elevated IGF 2-expression has been documented in various Wilms' tumors and a defect in the IGF 2 gene has been noted in 1 case. Southern blot analysis o... | v2 |
2018-04-03T00:59:39.082Z | 2013-12-04T00:00:00.000Z | 27487860 | s2ag/train | Effects of exercise dose and type during breast cancer chemotherapy: multicenter randomized trial.
BACKGROUND
Exercise improves physical functioning and symptom management during breast cancer chemotherapy, but the effects of different doses and types of exercise are unknown.
METHODS
A multicenter trial in Canada ra... | v2 |
2018-04-03T06:13:46.494Z | 2009-11-01T00:00:00.000Z | 46125910 | s2ag/train | [Prognostic value of FDG-PET in Hodgkin lymphoma for posttreatment evaluation. Long-term follow-up results].
UNLABELLED
In the past few decades Hodgkin lymphoma (HL) has become a highly curable malignant disease, as a result of using modern polychemotherapy and irradiation. Differentiation of active tumor from fibrosi... | v2 |
2017-08-03T00:18:05.031Z | 2007-01-01T00:00:00.000Z | 8207360 | s2ag/train | Colorectal cancer screening disparities related to obesity and gender
BACKGROUND: Obesity is associated with a higher incidence of colorectal cancer and increased colorectal cancer mortality. Obese women are less likely to undergo breast and cervical cancer screening than nonobese women. It is not known whether obesit... | v2 |
2018-01-24T17:25:33.048Z | 2013-11-01T00:00:00.000Z | 7551760 | s2ag/train | Patient-oncologist cost communication, financial distress, and medication adherence.
2 Background: Little is known about the association between patient-oncologist discussion of cancer treatment out-of-pocket (OOP) cost and medication adherence, a critical component of quality cancer care.
METHODS
We conducted a cro... | v2 |
2018-04-03T00:32:11.896Z | 2016-08-01T00:00:00.000Z | 207141110 | s2ag/train | Role of protein S in castration-resistant prostate cancer-like cells.
Understanding how castration-resistant prostate cancer (CRPC) cells survive the androgen-deprivation condition is crucial for treatment of this advanced prostate cancer (PCa). Here, we reported for the first time the up-regulation of protein S (PROS... | v2 |
2021-05-10T00:04:02.707Z | 2021-02-01T00:00:00.000Z | 234058610 | s2ag/train | Improving the growth and productivity of faba bean (Vicia faba L.) under deficit irrigation conditions by spraying of potassium selenate and potassium silicate
Water stress is one of the vitally essential environmental stresses that directly affect agricultural production, particularly in arid and semi-arid regions th... | v2 |
2019-03-30T13:06:33.733Z | 2003-09-01T00:00:00.000Z | 85989800 | s2ag/train | Book Review: Ocular Tumors of Humans and Animals
As anyone familiar with the fields of veterinary ophthalmology and veterinary ophthalmic pathology can attest, there is a need for textbooks integrating these two disciplines that are fairly comprehensive, yet concise enough to be read and mastered in a relatively short... | v2 |
2018-04-03T00:44:17.254Z | 2008-09-01T00:00:00.000Z | 22917800 | s2ag/train | [Mohs paste for unresectable local lesion of breast cancer].
A 45-year-old woman with a local recurrence on her left chest wall discharged massive exudates. At every gauze exchange, blood was still oozing out. After using Mohs paste twice, the surface had been fixed chemically and dried up, so she did not have to exch... | v2 |
2018-04-03T00:25:55.453Z | 2017-01-01T00:00:00.000Z | 4150200 | s2ag/train | Successful resection of asymptomatic paraganglioma mimicking lymph node metastasis from gastric cancer 5 years after distal gastrectomy:a case report.
A 61-year-old man visited our hospital for treatment of a retroperitoneal tumor. The patient had undergone distal gastrectomy for gastric cancer in the past. At 5 years... | v2 |
2017-08-15T22:26:19.741Z | 2006-08-01T00:00:00.000Z | 11647150 | s2ag/train | Cimetidine Induces Interleukin-18 Production through H2-Agonist Activity in Monocytes
The present study demonstrates a possible mechanism for the improvement of gastrointestinal cancer patients' prognosis by the histamine receptor type 2 (H2R) antagonist cimetidine. This agent, but not the H2R antagonists ranitidine a... | v2 |
2017-11-02T18:38:02.687Z | 2010-01-01T00:00:00.000Z | 2560300 | s2ag/train | Splenectomy during secondary cytoreductive surgery for epithelial ovarian cancer.
Splenic metastasis from ovarian cancer is unusual. Most splenic metastases are encountered in the setting of widespread visceral metastases. We present 6 cases of splenic metastasis of epithelial ovarian cancer. Three cases underwent a s... | v2 |
2019-03-07T14:18:27.832Z | 2014-12-01T00:00:00.000Z | 70484910 | s2ag/train | P215 Referral Patterns For Mediastinal Staging With Ebus Across A Lung Cancer Network A Report From The Manchester Cancer Ebus Sub-group
Introduction Manchester Cancer is a large Cancer Network in the North West of England, consisting of ten NHS Trusts. There is known variability in lung cancer outcomes across the ten... | v2 |
2021-07-27T00:06:05.561Z | 2021-05-20T00:00:00.000Z | 236368500 | s2ag/train | Long-term follow up of patients with mesothelioma treated with dendritic cell therapy in three phase I trials.
2618 Background: Immunotherapy targeting PD-(L)1 has become indispensable in the treatment of many malignant tumors. Recently, checkpoint inhibition using anti-PD-1 in combination with anti-CTLA-4 was proved ... | v2 |
2018-04-03T02:19:24.684Z | 2006-02-01T00:00:00.000Z | 33175310 | s2ag/train | Cell proliferation depends on mitochondrial Ca2+ uptake: inhibition by salicylate
Store‐operated Ca2+ entry (SOCE) is a ubiquitous Ca2+ influx pathway involved in control of multiple cellular and physiological processes including cell proliferation. Recent evidence has shown that SOCE depends critically on mitochondri... | v2 |
2018-04-03T02:20:58.541Z | 2015-09-15T00:00:00.000Z | 33345260 | s2ag/train | Prognostic factors and immunobiologic insights into Merkel cell carcinoma
Merkel cell carcinoma (MCC) is a rare cutaneous neuroendocrine cancer that has a propensity for local recurrence and nodal and distant metastasis. For patients with MCC, reported 5-year overall survival (OS) rates vary widely and range from 40% ... | v2 |
2018-04-03T04:38:10.854Z | 2008-09-01T00:00:00.000Z | 25322960 | s2ag/train | Can we still afford bladder cancer?
Purpose of review Bladder cancer is the most expensive tumor with regard to both costs per patient per year and lifetime costs per patient. Nonmuscle invasive tumors account for the highest share of the overall costs for bladder cancer. Costs for follow-up (excluding costs for reint... | v2 |
2017-06-17T01:26:58.158Z | 2012-01-01T00:00:00.000Z | 7625260 | s2ag/train | Objective assessment of postoperative gastrointestinal motility in elective colonic resection using a radiopaque marker provides an evidence for the abandonment of preoperative mechanical bowel preparation.
BACKGROUND
It has been suggested that mechanical bowel preparation (MBP) has no benefit in terms of anastomotic ... | v2 |
2018-04-03T04:21:37.229Z | 2018-07-01T00:00:00.000Z | 3640710 | s2ag/train | Loss of pRB in Conjunctival Squamous Cell Carcinoma: A Predictor of Poor Prognosis
Conjunctival squamous cell carcinoma (SCC) is the most common tumor of conjunctival epithelium. It is associated with risk of permanent visual impairment and has the capability to recur, metastasize, and cause death. Deregulation of cel... | v2 |
2018-04-03T03:06:25.655Z | 1989-04-01T00:00:00.000Z | 235860 | s2ag/train | [Effects of sulbactam/cefoperazone in patients with respiratory infections in aged and/or with underlying respiratory diseases].
Sulbactam/cefoperazone (SBT/CPZ), a new antibacterial drug, was administered to 14 cases with respiratory infections for a duration of 5 approximately 13 days at a daily dose of 4 g. Diagnos... | v2 |
2018-04-03T01:54:55.019Z | 2007-09-01T00:00:00.000Z | 31446560 | s2ag/train | Hypoxia inducible factor‐1 influences sensitivity to paclitaxel of human lung cancer cell lines under normoxic conditions
Paclitaxel (PTX) is an anticancer drug that is effective against a wide range of solid tumors. The effect of PTX on two human lung cancer cell lines, PC14PE6 and NCI‐H441 cells, was examined in an ... | v2 |
2018-04-03T04:01:06.032Z | 2011-11-01T00:00:00.000Z | 37329360 | s2ag/train | Human papillomavirus entry into NK cells requires CD16 expression and triggers cytotoxic activity and cytokine secretion
Human papillomavirus (HPV) infections account for more than 50% of infection‐linked cancers in women worldwide. The immune system controls, at least partially, viral infection and around 90% of HPV‐... | v2 |
2018-04-03T00:53:27.506Z | 2010-10-10T00:00:00.000Z | 2778750 | s2ag/train | A decade of surgically removed small renal masses in the Netherlands: characteristics and trends in type of surgery and pathologic reporting.
PURPOSE
To assess nationwide the pathologic characteristics and trends in type of surgery and pathologic reporting in surgically managed renal tumors ≤ 4 cm.
MATERIALS AND MET... | v2 |
2021-11-04T15:27:26.769Z | 2021-11-02T00:00:00.000Z | 242076050 | s2ag/train | Search of Predictors of Radiosensitivity in Rectal Adenocarcinoma
Purpose: To analyze a number of immunohistochemical markers as predictors of the radiosensitivity of rectal adenocarcinoma.
Material and methods: The study included 122 patients with histologically verified rectal adenocarcinoma, varying degrees of dif... | v2 |
2018-04-03T01:31:12.738Z | 1972-09-01T00:00:00.000Z | 29889750 | s2ag/train | Interaction between placental alkaline phosphatase and ABO system polymorphisms during intrauterine life.
The alkaline phosphatase of human placenta differs from that produced by other organs in a number of physicochemical characteristics including heat resistance, substrate specificity, antigenic properties, electrop... | v2 |
2019-03-12T13:05:11.448Z | 2014-01-01T00:00:00.000Z | 74585150 | s2ag/train | Management Of Oral Squamous Cell Carcinoma With Clinically Negative Neck - A Case Report And Review Of Literature
The management of N0 neck is still controversial. Although the decision to observe or treat the N0 neck is left to the choice of the patient and the head and neck oncologist, in oral cavity carcinoma the o... | v2 |
2017-06-19T20:32:35.475Z | 2003-09-01T00:00:00.000Z | 34153260 | s2ag/train | Distinct mechanisms mediate the initial and sustained phases of cell migration in epidermal growth factor receptor-overexpressing cells.
Elevated levels of epidermal growth factor receptor (EGFR) are predictive of increased invasion and metastasis in many human cancers. In the present study, we have shown that two dis... | v2 |
2018-01-24T17:25:33.048Z | 2011-05-20T00:00:00.000Z | 7173210 | s2ag/train | Meta-analyses of 22 randomized trials assessing the influence of chemotherapy in advanced/recurrent gastric cancer.
4109 Background: Advanced or recurrent stomach cancer remains an incurable disease and little progress has been obtained in prolonging survival. Multiple drugs and combinations of chemotherapy (CT) have ... | v2 |
2018-04-03T04:20:19.014Z | 2012-05-15T00:00:00.000Z | 38618960 | s2ag/train | A pilot study of urinary microRNA as a biomarker for urothelial cancer.
OBJECTIVE
MicroRNAs (miRNAs) are part of a class of small ribonucleic acid (RNAs). They are important regulatory molecules, involved in several cell processes, such as developmental timing, stem cell division and apoptosis. Dysregulated miRNAs hav... | v2 |
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Pes2o Cancer-filtered Dataset
This is a 3-way merged dataset of the allenai/peS2o academic paper dataset filtered with (cancer | oncology | tumor | tumour | oncogene | malignancy) + ((patient | human | rat | mouse) | (safety + dog)) query with about 1.7M specimens in train and 6k in validation. This query returns data in the dataset up until 2023-01.
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