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The dataset generation failed
Error code: DatasetGenerationError
Exception: ArrowInvalid
Message: Failed to parse string: 'x.doi.org/10.1093/pubmed/fdaa213' as a scalar of type int64
Traceback: Traceback (most recent call last):
File "/src/services/worker/.venv/lib/python3.9/site-packages/datasets/builder.py", line 2011, in _prepare_split_single
writer.write_table(table)
File "/src/services/worker/.venv/lib/python3.9/site-packages/datasets/arrow_writer.py", line 585, in write_table
pa_table = table_cast(pa_table, self._schema)
File "/src/services/worker/.venv/lib/python3.9/site-packages/datasets/table.py", line 2302, in table_cast
return cast_table_to_schema(table, schema)
File "/src/services/worker/.venv/lib/python3.9/site-packages/datasets/table.py", line 2261, in cast_table_to_schema
arrays = [cast_array_to_feature(table[name], feature) for name, feature in features.items()]
File "/src/services/worker/.venv/lib/python3.9/site-packages/datasets/table.py", line 2261, in <listcomp>
arrays = [cast_array_to_feature(table[name], feature) for name, feature in features.items()]
File "/src/services/worker/.venv/lib/python3.9/site-packages/datasets/table.py", line 1802, in wrapper
return pa.chunked_array([func(chunk, *args, **kwargs) for chunk in array.chunks])
File "/src/services/worker/.venv/lib/python3.9/site-packages/datasets/table.py", line 1802, in <listcomp>
return pa.chunked_array([func(chunk, *args, **kwargs) for chunk in array.chunks])
File "/src/services/worker/.venv/lib/python3.9/site-packages/datasets/table.py", line 2116, in cast_array_to_feature
return array_cast(
File "/src/services/worker/.venv/lib/python3.9/site-packages/datasets/table.py", line 1804, in wrapper
return func(array, *args, **kwargs)
File "/src/services/worker/.venv/lib/python3.9/site-packages/datasets/table.py", line 1963, in array_cast
return array.cast(pa_type)
File "pyarrow/array.pxi", line 996, in pyarrow.lib.Array.cast
File "/src/services/worker/.venv/lib/python3.9/site-packages/pyarrow/compute.py", line 404, in cast
return call_function("cast", [arr], options, memory_pool)
File "pyarrow/_compute.pyx", line 590, in pyarrow._compute.call_function
File "pyarrow/_compute.pyx", line 385, in pyarrow._compute.Function.call
File "pyarrow/error.pxi", line 154, in pyarrow.lib.pyarrow_internal_check_status
File "pyarrow/error.pxi", line 91, in pyarrow.lib.check_status
pyarrow.lib.ArrowInvalid: Failed to parse string: 'x.doi.org/10.1093/pubmed/fdaa213' as a scalar of type int64
The above exception was the direct cause of the following exception:
Traceback (most recent call last):
File "/src/services/worker/src/worker/job_runners/config/parquet_and_info.py", line 1529, in compute_config_parquet_and_info_response
parquet_operations = convert_to_parquet(builder)
File "/src/services/worker/src/worker/job_runners/config/parquet_and_info.py", line 1154, in convert_to_parquet
builder.download_and_prepare(
File "/src/services/worker/.venv/lib/python3.9/site-packages/datasets/builder.py", line 1027, in download_and_prepare
self._download_and_prepare(
File "/src/services/worker/.venv/lib/python3.9/site-packages/datasets/builder.py", line 1122, in _download_and_prepare
self._prepare_split(split_generator, **prepare_split_kwargs)
File "/src/services/worker/.venv/lib/python3.9/site-packages/datasets/builder.py", line 1882, in _prepare_split
for job_id, done, content in self._prepare_split_single(
File "/src/services/worker/.venv/lib/python3.9/site-packages/datasets/builder.py", line 2038, in _prepare_split_single
raise DatasetGenerationError("An error occurred while generating the dataset") from e
datasets.exceptions.DatasetGenerationError: An error occurred while generating the datasetNeed help to make the dataset viewer work? Make sure to review how to configure the dataset viewer, and open a discussion for direct support.
cord_uid string | sha string | source_x string | title string | doi string | pmcid string | pubmed_id int64 | license string | abstract string | publish_time string | authors string | journal string | mag_id null | who_covidence_id null | arxiv_id null | pdf_json_files string | pmc_json_files string | url string | s2_id null |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
ug7v899j | d1aafb70c066a2068b02786f8929fd9c900897fb | PMC | Clinical features of culture-proven Mycoplasma pneumoniae infections at King Abdulaziz University Hospital, Jeddah, Saudi Arabia | 10.1186/1471-2334-1-6 | PMC35282 | 11,472,636 | no-cc | OBJECTIVE: This retrospective chart review describes the epidemiology and clinical features of 40 patients with culture-proven Mycoplasma pneumoniae infections at King Abdulaziz University Hospital, Jeddah, Saudi Arabia. METHODS: Patients with positive M. pneumoniae cultures from respiratory specimens from January 1997... | 2001-07-04 | Madani, Tariq A; Al-Ghamdi, Aisha A | BMC Infect Dis | null | null | null | document_parses/pdf_json/d1aafb70c066a2068b02786f8929fd9c900897fb.json | document_parses/pmc_json/PMC35282.xml.json | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC35282/ | null |
02tnwd4m | 6b0567729c2143a66d737eb0a2f63f2dce2e5a7d | PMC | Nitric oxide: a pro-inflammatory mediator in lung disease? | 10.1186/rr14 | PMC59543 | 11,667,967 | no-cc | Inflammatory diseases of the respiratory tract are commonly associated with elevated production of nitric oxide (NO•) and increased indices of NO• -dependent oxidative stress. Although NO• is known to have anti-microbial, anti-inflammatory and anti-oxidant properties, various lines of evidence support the contribution ... | 2000-08-15 | Vliet, Albert van der; Eiserich, Jason P; Cross, Carroll E | Respir Res | null | null | null | document_parses/pdf_json/6b0567729c2143a66d737eb0a2f63f2dce2e5a7d.json | document_parses/pmc_json/PMC59543.xml.json | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC59543/ | null |
ejv2xln0 | 06ced00a5fc04215949aa72528f2eeaae1d58927 | PMC | Surfactant protein-D and pulmonary host defense | 10.1186/rr19 | PMC59549 | 11,667,972 | no-cc | Surfactant protein-D (SP-D) participates in the innate response to inhaled microorganisms and organic antigens, and contributes to immune and inflammatory regulation within the lung. SP-D is synthesized and secreted by alveolar and bronchiolar epithelial cells, but is also expressed by epithelial cells lining various e... | 2000-08-25 | Crouch, Erika C | Respir Res | null | null | null | document_parses/pdf_json/06ced00a5fc04215949aa72528f2eeaae1d58927.json | document_parses/pmc_json/PMC59549.xml.json | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC59549/ | null |
2b73a28n | 348055649b6b8cf2b9a376498df9bf41f7123605 | PMC | Role of endothelin-1 in lung disease | 10.1186/rr44 | PMC59574 | 11,686,871 | no-cc | Endothelin-1 (ET-1) is a 21 amino acid peptide with diverse biological activity that has been implicated in numerous diseases. ET-1 is a potent mitogen regulator of smooth muscle tone, and inflammatory mediator that may play a key role in diseases of the airways, pulmonary circulation, and inflammatory lung diseases, b... | 2001-02-22 | Fagan, Karen A; McMurtry, Ivan F; Rodman, David M | Respir Res | null | null | null | document_parses/pdf_json/348055649b6b8cf2b9a376498df9bf41f7123605.json | document_parses/pmc_json/PMC59574.xml.json | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC59574/ | null |
9785vg6d | 5f48792a5fa08bed9f56016f4981ae2ca6031b32 | PMC | Gene expression in epithelial cells in response to pneumovirus infection | 10.1186/rr61 | PMC59580 | 11,686,888 | no-cc | Respiratory syncytial virus (RSV) and pneumonia virus of mice (PVM) are viruses of the family Paramyxoviridae, subfamily pneumovirus, which cause clinically important respiratory infections in humans and rodents, respectively. The respiratory epithelial target cells respond to viral infection with specific alterations ... | 2001-05-11 | Domachowske, Joseph B; Bonville, Cynthia A; Rosenberg, Helene F | Respir Res | null | null | null | document_parses/pdf_json/5f48792a5fa08bed9f56016f4981ae2ca6031b32.json | document_parses/pmc_json/PMC59580.xml.json | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC59580/ | null |
zjufx4fo | b2897e1277f56641193a6db73825f707eed3e4c9 | PMC | Sequence requirements for RNA strand transfer during nidovirus discontinuous subgenomic RNA synthesis | 10.1093/emboj/20.24.7220 | PMC125340 | 11,742,998 | green-oa | Nidovirus subgenomic mRNAs contain a leader sequence derived from the 5′ end of the genome fused to different sequences (‘bodies’) derived from the 3′ end. Their generation involves a unique mechanism of discontinuous subgenomic RNA synthesis that resembles copy-choice RNA recombination. During this process, the nascen... | 2001-12-17 | Pasternak, Alexander O.; van den Born, Erwin; Spaan, Willy J.M.; Snijder, Eric J. | The EMBO Journal | null | null | null | document_parses/pdf_json/b2897e1277f56641193a6db73825f707eed3e4c9.json | document_parses/pmc_json/PMC125340.xml.json | http://europepmc.org/articles/pmc125340?pdf=render | null |
5yhe786e | 3bb07ea10432f7738413dff9816809cc90f03f99 | PMC | Debate: Transfusing to normal haemoglobin levels will not improve outcome | 10.1186/cc987 | PMC137267 | 11,299,062 | no-cc | Recent evidence suggests that critically ill patients are able to tolerate lower levels of haemoglobin than was previously believed. It is our goal to show that transfusing to a level of 100 g/l does not improve mortality and other clinically important outcomes in a critical care setting. Although many questions remain... | 2001-03-08 | Alvarez, Gonzalo; Hébert, Paul C; Szick, Sharyn | Crit Care | null | null | null | document_parses/pdf_json/3bb07ea10432f7738413dff9816809cc90f03f99.json | document_parses/pmc_json/PMC137267.xml.json | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC137267/ | null |
8zchiykl | 5806726a24dc91de3954001effbdffd7a82d54e2 | PMC | The 21st International Symposium on Intensive Care and Emergency Medicine, Brussels, Belgium, 20-23 March 2001 | 10.1186/cc1013 | PMC137274 | 11,353,930 | no-cc | The 21st International Symposium on Intensive Care and Emergency Medicine was dominated by the results of recent clinical trials in sepsis and acute respiratory distress syndrome (ARDS). The promise of extracorporeal liver replacement therapy and noninvasive ventilation were other areas of interest. Ethical issues also... | 2001-05-02 | Ball, Jonathan; Venn, Richard | Crit Care | null | null | null | document_parses/pdf_json/5806726a24dc91de3954001effbdffd7a82d54e2.json | document_parses/pmc_json/PMC137274.xml.json | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC137274/ | null |
8qnrcgnk | faaf1022ccfe93b032c5608097a53543ba24aedb | PMC | Heme oxygenase-1 and carbon monoxide in pulmonary medicine | 10.1186/1465-9921-4-7 | PMC193681 | 12,964,953 | no-cc | Heme oxygenase-1 (HO-1), an inducible stress protein, confers cytoprotection against oxidative stress in vitro and in vivo. In addition to its physiological role in heme degradation, HO-1 may influence a number of cellular processes, including growth, inflammation, and apoptosis. By virtue of anti-inflammatory effects,... | 2003-08-07 | Slebos, Dirk-Jan; Ryter, Stefan W; Choi, Augustine MK | Respir Res | null | null | null | document_parses/pdf_json/faaf1022ccfe93b032c5608097a53543ba24aedb.json | document_parses/pmc_json/PMC193681.xml.json | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC193681/ | null |
jg13scgo | 5b44feca5d6ffaaeb66501fa84cc6dd44d06660a | PMC | Technical Description of RODS: A Real-time Public Health Surveillance System | 10.1197/jamia.m1345 | PMC212776 | 12,807,803 | bronze-oa | This report describes the design and implementation of the Real-time Outbreak and Disease Surveillance (RODS) system, a computer-based public health surveillance system for early detection of disease outbreaks. Hospitals send RODS data from clinical encounters over virtual private networks and leased lines using the He... | 2003-09-01 | Tsui, Fu-Chiang; Espino, Jeremy U.; Dato, Virginia M.; Gesteland, Per H.; Hutman, Judith; Wagner, Michael M. | Journal of the American Medical Informatics Association | null | null | null | document_parses/pdf_json/5b44feca5d6ffaaeb66501fa84cc6dd44d06660a.json | document_parses/pmc_json/PMC212776.xml.json | https://academic.oup.com/jamia/article-pdf/10/5/399/2352016/10-5-399.pdf | null |
5tkvsudh | 9d4e3e8eb092d5ed282d0aa4aadcaa8b7165b5e9 | PMC | Conservation of polyamine regulation by translational frameshifting from yeast to mammals | 10.1093/emboj/19.8.1907 | PMC302018 | 10,775,274 | no-cc | Regulation of ornithine decarboxylase in vertebrates involves a negative feedback mechanism requiring the protein antizyme. Here we show that a similar mechanism exists in the fission yeast Schizosaccharomyces pombe. The expression of mammalian antizyme genes requires a specific +1 translational frameshift. The efficie... | 2000-04-17 | Ivanov, Ivaylo P.; Matsufuji, Senya; Murakami, Yasuko; Gesteland, Raymond F.; Atkins, John F. | EMBO J | null | null | null | document_parses/pdf_json/9d4e3e8eb092d5ed282d0aa4aadcaa8b7165b5e9.json | document_parses/pmc_json/PMC302018.xml.json | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC302018/ | null |
6lvn10f4 | 14e0cac6e86d62859e6c9f1351ab67466d89e5b3 | PMC | Heterogeneous nuclear ribonucleoprotein A1 regulates RNA synthesis of a cytoplasmic virus | 10.1093/emboj/19.17.4701 | PMC302072 | 10,970,862 | green-oa | Heterogeneous nuclear ribonucleoprotein (hnRNP A1) is involved in pre-mRNA splicing in the nucleus and translational regulation in the cytoplasm. In the present study, we demonstrate that hnRNP A1 also participates in the transcription and replication of a cytoplasmic RNA virus, mouse hepatitis virus (MHV). Overexpress... | 2000-09-01 | Shi, Stephanie T.; Huang, Peiyong; Li, Hsin-Pai; Lai, Michael M.C. | The EMBO Journal | null | null | null | document_parses/pdf_json/14e0cac6e86d62859e6c9f1351ab67466d89e5b3.json | document_parses/pmc_json/PMC302072.xml.json | http://europepmc.org/articles/pmc302072?pdf=render | null |
tvxpckxo | d09b79026117ec9faebba46a8d13aa9b23ec751e | PMC | A Method to Identify p62's UBA Domain Interacting Proteins | 10.1251/bpo66 | PMC302190 | 14,702,098 | no-cc | The UBA domain is a conserved sequence motif among polyubiquitin binding proteins. For the first time, we demonstrate a systematic, high throughput approach to identification of UBA domain-interacting proteins from a proteome-wide perspective. Using the rabbit reticulocyte lysate in vitro expression cloning system, we ... | 2003-12-12 | Pridgeon, Julia W.; Geetha, Thangiah; Wooten, Marie W. | Biol Proced Online | null | null | null | document_parses/pdf_json/d09b79026117ec9faebba46a8d13aa9b23ec751e.json | document_parses/pmc_json/PMC302190.xml.json | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC302190/ | null |
mcuixluu | 44102e3e69e70ad2a73e753133283334ce1f8736 | PMC | Vaccinia virus infection disrupts microtubule organization and centrosome function | 10.1093/emboj/19.15.3932 | PMC306617 | 10,921,875 | green-oa | We examined the role of the microtubule cytoskeleton during vaccinia virus infection. We found that newly assembled virus particles accumulate in the vicinity of the microtubule-organizing centre in a microtubule- and dynein–dynactin complex-dependent fashion. Microtubules are required for efficient intracellular matur... | 2000-08-01 | Ploubidou, Aspasia; Moreau, Violaine; Ashman, Keith; Reckmann, Inge; González, Cayetano; Way, Michael | The EMBO Journal | null | null | null | document_parses/pdf_json/44102e3e69e70ad2a73e753133283334ce1f8736.json | document_parses/pmc_json/PMC306617.xml.json | http://europepmc.org/articles/pmc306617?pdf=render | null |
6iu1dtyl | 6e8517cb25ff228cb48da90a9c97d9c274dc8031 | PMC | The site of origin of the 1918 influenza pandemic and its public health implications | 10.1186/1479-5876-2-3 | PMC340389 | 14,733,617 | no-cc | null | 2004-01-20 | Barry, John M | J Transl Med | null | null | null | document_parses/pdf_json/6e8517cb25ff228cb48da90a9c97d9c274dc8031.json | document_parses/pmc_json/PMC340389.xml.json | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC340389/ | null |
t35n7bk9 | 30a4842a2e257f725cc041e32fd682c495111a50 | PMC | Multi-faceted, multi-versatile microarray: simultaneous detection of many viruses and their expression profiles | 10.1186/1742-4690-1-11 | PMC420498 | 15,169,556 | no-cc | There are hundreds of viruses that infect different human organs and cause diseases. Some fatal emerging viral infections have become serious public health issues worldwide. Early diagnosis and subsequent treatment are therefore essential for fighting viral infections. Current diagnostic techniques frequently employ po... | 2004-05-26 | Shieh, Biehuoy; Li, Ching | Retrovirology | null | null | null | document_parses/pdf_json/30a4842a2e257f725cc041e32fd682c495111a50.json | document_parses/pmc_json/PMC420498.xml.json | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC420498/ | null |
eiqypt0m | 6a8ac55ea2a1fbd99deb683e24dd986e55e707b3 | PMC | Herpes simplex virus type 1 and normal protein permeability in the lungs of critically ill patients: a case for low pathogenicity? | 10.1186/cc2850 | PMC468896 | 15,153,242 | no-cc | INTRODUCTION: The pathogenicity of late respiratory infections with herpes simplex virus type 1 (HSV-1) in the critically ill is unclear. METHODS: In four critically ill patients with persistent pulmonary infiltrates of unknown origin and isolation of HSV-1 from tracheal aspirate or bronchoalveolar lavage fluid, at 7 (... | 2004-03-31 | Verheij, Joanne; Groeneveld, AB Johan; Beishuizen, Albertus; Lingen, Arthur van; Simoons-Smit, Alberdina M; van Schijndel, Rob JM Strack | Crit Care | null | null | null | document_parses/pdf_json/6a8ac55ea2a1fbd99deb683e24dd986e55e707b3.json | document_parses/pmc_json/PMC468896.xml.json | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC468896/ | null |
sgmk96vr | 367af6bb9a8bbda02206506a819656bb6f14ce4c | PMC | Logistics of community smallpox control through contact tracing and ring vaccination: a stochastic network model | 10.1186/1471-2458-4-34 | PMC520756 | 15,298,713 | cc-by | BACKGROUND: Previous smallpox ring vaccination models based on contact tracing over a network suggest that ring vaccination would be effective, but have not explicitly included response logistics and limited numbers of vaccinators. METHODS: We developed a continuous-time stochastic simulation of smallpox transmission, ... | 2004-08-06 | Porco, Travis C; Holbrook, Karen A; Fernyak, Susan E; Portnoy, Diane L; Reiter, Randy; Aragón, Tomás J | BMC Public Health | null | null | null | document_parses/pdf_json/367af6bb9a8bbda02206506a819656bb6f14ce4c.json | document_parses/pmc_json/PMC520756.xml.json | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC520756/ | null |
di0fcy0j | 4df2c6eecb985fcb20da3c5ed46e3b910c7077ab | PMC | Protection of pulmonary epithelial cells from oxidative stress by hMYH adenine glycosylase | 10.1186/1465-9921-5-16 | PMC521691 | 15,450,125 | cc-by | BACKGROUND: Oxygen toxicity is a major cause of lung injury. The base excision repair pathway is one of the most important cellular protection mechanisms that responds to oxidative DNA damage. Lesion-specific DNA repair enzymes include hOgg1, hMYH, hNTH and hMTH. METHODS: The above lesion-specific DNA repair enzymes we... | 2004-09-27 | Kremer, Ted M; Rinne, Mikael L; Xu, Yi; Chen, Xian Ming; Kelley, Mark R | Respir Res | null | null | null | document_parses/pdf_json/4df2c6eecb985fcb20da3c5ed46e3b910c7077ab.json | document_parses/pmc_json/PMC521691.xml.json | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC521691/ | null |
4k8f7ou1 | 83b05e8afa6cbe7a68170ee155f7eca37c91d51f | PMC | Bioinformatic mapping of AlkB homology domains in viruses | 10.1186/1471-2164-6-1 | PMC544882 | 15,627,404 | cc-by | BACKGROUND: AlkB-like proteins are members of the 2-oxoglutarate- and Fe(II)-dependent oxygenase superfamily. In Escherichia coli the protein protects RNA and DNA against damage from methylating agents. 1-methyladenine and 3-methylcytosine are repaired by oxidative demethylation and direct reversal of the methylated ba... | 2005-01-03 | Bratlie, Marit S; Drabløs, Finn | BMC Genomics | null | null | null | document_parses/pdf_json/83b05e8afa6cbe7a68170ee155f7eca37c91d51f.json | document_parses/pmc_json/PMC544882.xml.json | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC544882/ | null |
wnnsmx60 | 025339bfce1cb8efa81c5accdabefe04dcdac9d2 | PMC | Managing emerging infectious diseases: Is a federal system an impediment to effective laws? | 10.1186/1743-8462-1-7 | PMC544965 | 15,679,928 | cc-by | In the 1980's and 1990's HIV/AIDS was the emerging infectious disease. In 2003–2004 we saw the emergence of SARS, Avian influenza and Anthrax in a man made form used for bioterrorism. Emergency powers legislation in Australia is a patchwork of Commonwealth quarantine laws and State and Territory based emergency powers ... | 2004-11-19 | Howse, Genevieve | Aust New Zealand Health Policy | null | null | null | document_parses/pdf_json/025339bfce1cb8efa81c5accdabefe04dcdac9d2.json | document_parses/pmc_json/PMC544965.xml.json | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC544965/ | null |
gdsfkw1b | 8d7400a2b387820cd391d7df8194642e50402a0c | PMC | Protein secretion in Lactococcus lactis : an efficient way to increase the overall heterologous protein production | 10.1186/1475-2859-4-2 | PMC545053 | 15,631,634 | cc-by | Lactococcus lactis, the model lactic acid bacterium (LAB), is a food grade and well-characterized Gram positive bacterium. It is a good candidate for heterologous protein delivery in foodstuff or in the digestive tract. L. lactis can also be used as a protein producer in fermentor. Many heterologous proteins have alrea... | 2005-01-04 | Le Loir, Yves; Azevedo, Vasco; Oliveira, Sergio C; Freitas, Daniela A; Miyoshi, Anderson; Bermúdez-Humarán, Luis G; Nouaille, Sébastien; Ribeiro, Luciana A; Leclercq, Sophie; Gabriel, Jane E; Guimaraes, Valeria D; Oliveira, Maricê N; Charlier, Cathy; Gautier, Michel; Langella, Philippe | Microb Cell Fact | null | null | null | document_parses/pdf_json/8d7400a2b387820cd391d7df8194642e50402a0c.json | document_parses/pmc_json/PMC545053.xml.json | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC545053/ | null |
yba7mdtb | f1d1b9694aa43c837d9b758cb2d45d8a24d293e3 | PMC | Detection and characterization of horizontal transfers in prokaryotes using genomic signature | 10.1093/nar/gni004 | PMC546175 | 15,653,627 | no-cc | Horizontal DNA transfer is an important factor of evolution and participates in biological diversity. Unfortunately, the location and length of horizontal transfers (HTs) are known for very few species. The usage of short oligonucleotides in a sequence (the so-called genomic signature) has been shown to be species-spec... | 2005-01-13 | Dufraigne, Christine; Fertil, Bernard; Lespinats, Sylvain; Giron, Alain; Deschavanne, Patrick | Nucleic Acids Res | null | null | null | document_parses/pdf_json/f1d1b9694aa43c837d9b758cb2d45d8a24d293e3.json | document_parses/pmc_json/PMC546175.xml.json | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC546175/ | null |
bbvxu8op | 867e1b0f6ca8757f2a32a625d99b23888ab40d49 | PMC | Comparisons of substitution, insertion and deletion probes for resequencing and mutational analysis using oligonucleotide microarrays | 10.1093/nar/gni034 | PMC549431 | 15,722,479 | no-cc | Although oligonucleotide probes complementary to single nucleotide substitutions are commonly used in microarray-based screens for genetic variation, little is known about the hybridization properties of probes complementary to small insertions and deletions. It is necessary to define the hybridization properties of th... | 2005-02-18 | Karaman, Mazen W.; Groshen, Susan; Lee, Chi-Chiang; Pike, Brian L.; Hacia, Joseph G. | Nucleic Acids Res | null | null | null | document_parses/pdf_json/867e1b0f6ca8757f2a32a625d99b23888ab40d49.json | document_parses/pmc_json/PMC549431.xml.json | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC549431/ | null |
e62cfqt7 | b022e6ee1e7b9a0a822b1255c2fa12f81ddc52fd | PMC | A Gene Encoding Sialic-Acid-Specific 9-O-Acetylesterase Found in Human Adult Testis | 10.1155/s1110724304307084 | PMC551583 | 15,292,578 | no-cc | Using differential display RT-PCR, we identified a gene of 2750 bp from human adult testis, named H-Lse, which encoded a putative protein of 523 amino acids and molecular weight of 58 kd with structural characteristics similar to that of mouse lysosome sialic-acid-specific 9-O-acetylesterase. Northern blot analysis sho... | 2004-07-29 | Zhu, Hu; Chang Chan, Hsiao; Zhou, Zuoming; Li, Jianming; Zhu, Hui; Yin, Lanlan; Xu, Ming; Cheng, Lijun; Sha, Jiahao | J Biomed Biotechnol | null | null | null | document_parses/pdf_json/b022e6ee1e7b9a0a822b1255c2fa12f81ddc52fd.json | document_parses/pmc_json/PMC551583.xml.json | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC551583/ | null |
4cvy9u28 | f1bbb1b2e330c440acd6ff3d8a0f0d2e5adedd70 | PMC | The role of mast cells in the pathogenesis of pain in chronic pancreatitis | 10.1186/1471-230x-5-8 | PMC554992 | 15,745,445 | cc-by | BACKGROUND: The biological basis of pain in chronic pancreatitis is poorly understood. Mast cells have been implicated in the pathogenesis of pain in other conditions. We hypothesized that mast cells play a role in the pain of chronic pancreatitis. We examined the association of pain with mast cells in autopsy specimen... | 2005-03-03 | Hoogerwerf, Willemijntje A; Gondesen, Kelly; Xiao, Shu-Yuan; Winston, John H; Willis, William D; Pasricha, Pankaj J | BMC Gastroenterol | null | null | null | document_parses/pdf_json/f1bbb1b2e330c440acd6ff3d8a0f0d2e5adedd70.json | document_parses/pmc_json/PMC554992.xml.json | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC554992/ | null |
zowp10ts | 03203ab50eb64271a9e825f94a1b1a6c46ea14b3 | PMC | Recombination Every Day: Abundant Recombination in a Virus during a Single Multi-Cellular Host Infection | 10.1371/journal.pbio.0030089 | PMC1054884 | 15,737,066 | cc-by | Viral recombination can dramatically impact evolution and epidemiology. In viruses, the recombination rate depends on the frequency of genetic exchange between different viral genomes within an infected host cell and on the frequency at which such co-infections occur. While the recombination rate has been recently eval... | 2005-03-01 | Froissart, Remy; Roze, Denis; Uzest, Marilyne; Galibert, Lionel; Blanc, Stephane; Michalakis, Yannis | PLoS Biol | null | null | null | document_parses/pdf_json/03203ab50eb64271a9e825f94a1b1a6c46ea14b3.json | document_parses/pmc_json/PMC1054884.xml.json | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1054884/ | null |
5dk231qs | a77badb297bf4927419481e660ea8f1806ed91b1 | PMC | Torsional restraint: a new twist on frameshifting pseudoknots | 10.1093/nar/gki329 | PMC1072802 | 15,800,212 | no-cc | mRNA pseudoknots have a stimulatory function in programmed −1 ribosomal frameshifting (−1 PRF). Though we previously presented a model for how mRNA pseudoknots might activate the mechanism for −1 PRF, it did not address the question of the role that they may play in positioning the mRNA relative to the ribosome in this... | 2005-03-30 | Plant, Ewan P.; Dinman, Jonathan D. | Nucleic Acids Res | null | null | null | document_parses/pdf_json/a77badb297bf4927419481e660ea8f1806ed91b1.json | document_parses/pmc_json/PMC1072802.xml.json | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1072802/ | null |
snqdma0s | 93c6eef32a1a511ee989a259eab0e12174dc6859 | PMC | Correcting errors in synthetic DNA through consensus shuffling | 10.1093/nar/gni053 | PMC1072806 | 15,800,206 | no-cc | Although efficient methods exist to assemble synthetic oligonucleotides into genes and genomes, these suffer from the presence of 1–3 random errors/kb of DNA. Here, we introduce a new method termed consensus shuffling and demonstrate its use to significantly reduce random errors in synthetic DNA. In this method, errors... | 2005-03-30 | Binkowski, Brock F.; Richmond, Kathryn E.; Kaysen, James; Sussman, Michael R.; Belshaw, Peter J. | Nucleic Acids Res | null | null | null | document_parses/pdf_json/93c6eef32a1a511ee989a259eab0e12174dc6859.json | document_parses/pmc_json/PMC1072806.xml.json | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1072806/ | null |
1pq6dkl5 | 184aded923f0ac3cbdbcf74d2a5b42cda0f414c2 | PMC | Towards standardization of RNA quality assessment using user-independent classifiers of microcapillary electrophoresis traces | 10.1093/nar/gni054 | PMC1072807 | 15,800,207 | no-cc | While it is universally accepted that intact RNA constitutes the best representation of the steady-state of transcription, there is no gold standard to define RNA quality prior to gene expression analysis. In this report, we evaluated the reliability of conventional methods for RNA quality assessment including UV spect... | 2005-03-30 | Imbeaud, Sandrine; Graudens, Esther; Boulanger, Virginie; Barlet, Xavier; Zaborski, Patrick; Eveno, Eric; Mueller, Odilo; Schroeder, Andreas; Auffray, Charles | Nucleic Acids Res | null | null | null | document_parses/pdf_json/184aded923f0ac3cbdbcf74d2a5b42cda0f414c2.json | document_parses/pmc_json/PMC1072807.xml.json | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1072807/ | null |
754nln40 | 40e41f0c52b39669dee24e37875d7a9fabc38636 | PMC | Factors affecting translation at the programmed −1 ribosomal frameshifting site of Cocksfoot mottle virus RNA in vivo | 10.1093/nar/gki521 | PMC1083427 | 15,843,686 | no-cc | The ratio between proteins P27 and replicase of Cocksfoot mottle virus (CfMV) is regulated via a −1 programmed ribosomal frameshift (−1 PRF). A minimal frameshift signal with a slippery U UUA AAC heptamer and a downstream stem–loop structure was inserted into a dual reporter vector and directed −1 PRF with an efficienc... | 2005-04-20 | Mäkeläinen, Katri; Mäkinen, Kristiina | Nucleic Acids Res | null | null | null | document_parses/pdf_json/40e41f0c52b39669dee24e37875d7a9fabc38636.json | document_parses/pmc_json/PMC1083427.xml.json | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1083427/ | null |
p34ezktf | d77233dd9085c9c76787c84ee9a1e249424b283a | PMC | Australian public health policy in 2003 – 2004 | 10.1186/1743-8462-2-7 | PMC1087471 | 15,811,192 | cc-by | In Australia, compared with other developed countries the many and varied programs which comprise public health have continued to be funded poorly and unsystematically, particularly given the amount of publicly voiced political support. In 2003, the major public health policy developments in communicable disease contro... | 2005-04-06 | Lin, Vivian; Robinson, Priscilla | Aust New Zealand Health Policy | null | null | null | document_parses/pdf_json/d77233dd9085c9c76787c84ee9a1e249424b283a.json | document_parses/pmc_json/PMC1087471.xml.json | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1087471/ | null |
l3z27806 | 7d624acf891472c3452b1deb89e0dc44a40d0c94 | PMC | GIDEON: a comprehensive Web-based resource for geographic medicine | 10.1186/1476-072x-4-10 | PMC1090610 | 15,847,698 | cc-by | GIDEON (Global Infectious Diseases and Epidemiology Network) is a web-based computer program designed for decision support and informatics in the field of Geographic Medicine. The first of four interactive modules generates a ranked differential diagnosis based on patient signs, symptoms, exposure history and country o... | 2005-04-22 | Berger, Stephen A | Int J Health Geogr | null | null | null | document_parses/pdf_json/7d624acf891472c3452b1deb89e0dc44a40d0c94.json | document_parses/pmc_json/PMC1090610.xml.json | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1090610/ | null |
yz2wbpuu | d706e82e2ebc8571e70654d1acf0ffd3969ab2d3 | PMC | Globalization and Health | 10.1186/1744-8603-1-1 | PMC1143779 | 15,847,699 | cc-by | This debut editorial of Globalization and Health introduces the journal, briefly delineating its goals and objectives and outlines its scope of subject matter. 'Open Access' publishing is expected to become an increasingly important format for peer reviewed academic journals and that Globalization and Health is 'Open A... | 2005-04-22 | Martin, Greg | Global Health | null | null | null | document_parses/pdf_json/d706e82e2ebc8571e70654d1acf0ffd3969ab2d3.json | document_parses/pmc_json/PMC1143779.xml.json | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1143779/ | null |
kvhoa2se | ada57a9f084a016deb20b6f83c442072e6e37955 | PMC | The 'polysemous' codon--a codon with multiple amino acid assignment caused by dual specificity of tRNA identity. | 10.1093/emboj/16.5.1122 | PMC1169711 | 9,118,950 | no-cc | In some Candida species, the universal CUG leucine codon is translated as serine. However, in most cases, the serine tRNAs responsible for this non-universal decoding (tRNA(Ser)CAG) accept in vitro not only serine, but also, to some extent, leucine. Nucleotide replacement experiments indicated that m1G37 is critical fo... | 1997-03-03 | Suzuki, T; Ueda, T; Watanabe, K | EMBO J | null | null | null | document_parses/pdf_json/ada57a9f084a016deb20b6f83c442072e6e37955.json | null | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1169711/ | null |
cgl34ykt | 6eeaffdb22b4e310867262d1891a1442769c7803 | PMC | A universal BMV-based RNA recombination system—how to search for general rules in RNA recombination | 10.1093/nar/gni106 | PMC1174899 | 16,002,784 | no-cc | At present, there is no doubt that RNA recombination is one of the major factors responsible for the generation of new RNA viruses and retroviruses. Numerous experimental systems have been created to investigate this complex phenomenon. Consequently, specific RNA structural motifs mediating recombination have been iden... | 2005-07-07 | Alejska, Magdalena; Figlerowicz, Magdalena; Malinowska, Nelli; Urbanowicz, Anna; Figlerowicz, Marek | Nucleic Acids Res | null | null | null | document_parses/pdf_json/6eeaffdb22b4e310867262d1891a1442769c7803.json | document_parses/pmc_json/PMC1174899.xml.json | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1174899/ | null |
ajlctjeb | dff6195f5e24ebfa2fb4060142611b48021f673c | PMC | Neutrophil elastase, an acid-independent serine protease, facilitates reovirus uncoating and infection in U937 promonocyte cells | 10.1186/1743-422x-2-48 | PMC1180477 | 15,927,073 | cc-by | BACKGROUND: Mammalian reoviruses naturally infect their hosts through the enteric and respiratory tracts. During enteric infections, proteolysis of the reovirus outer capsid protein σ3 is mediated by pancreatic serine proteases. In contrast, the proteases critical for reovirus replication in the lung are unknown. Neutr... | 2005-05-31 | Golden, Joseph W; Schiff, Leslie A | Virol J | null | null | null | document_parses/pdf_json/dff6195f5e24ebfa2fb4060142611b48021f673c.json | document_parses/pmc_json/PMC1180477.xml.json | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1180477/ | null |
cl9gpt9w | 95aec306660c1b7519e9f019d92cc3a8206481e4 | PMC | The influence of locked nucleic acid residues on the thermodynamic properties of 2′-O-methyl RNA/RNA heteroduplexes | 10.1093/nar/gki789 | PMC1201327 | 16,155,181 | no-cc | The influence of locked nucleic acid (LNA) residues on the thermodynamic properties of 2′-O-methyl RNA/RNA heteroduplexes is reported. Optical melting studies indicate that LNA incorporated into an otherwise 2′-O-methyl RNA oligonucleotide usually, but not always, enhances the stabilities of complementary duplexes form... | 2005-09-09 | Kierzek, Elzbieta; Ciesielska, Anna; Pasternak, Karol; Mathews, David H.; Turner, Douglas H.; Kierzek, Ryszard | Nucleic Acids Res | null | null | null | document_parses/pdf_json/95aec306660c1b7519e9f019d92cc3a8206481e4.json | document_parses/pmc_json/PMC1201327.xml.json | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1201327/ | null |
t40ybhgb | d450fc8885843d48772df9a898552302f8c80b98 | PMC | Draft versus finished sequence data for DNA and protein diagnostic signature development | 10.1093/nar/gki896 | PMC1266063 | 16,243,783 | no-cc | Sequencing pathogen genomes is costly, demanding careful allocation of limited sequencing resources. We built a computational Sequencing Analysis Pipeline (SAP) to guide decisions regarding the amount of genomic sequencing necessary to develop high-quality diagnostic DNA and protein signatures. SAP uses simulations to ... | 2005-10-20 | Gardner, Shea N.; Lam, Marisa W.; Smith, Jason R.; Torres, Clinton L.; Slezak, Tom R. | Nucleic Acids Res | null | null | null | document_parses/pdf_json/d450fc8885843d48772df9a898552302f8c80b98.json | document_parses/pmc_json/PMC1266063.xml.json | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1266063/ | null |
zwbc7nnn | ae19236936b05793ceac08ed5d58269c25486320 | PMC | An ontology for immune epitopes: application to the design of a broad scope database of immune reactivities | 10.1186/1745-7580-1-2 | PMC1287064 | 16,305,755 | cc-by | BACKGROUND: Epitopes can be defined as the molecular structures bound by specific receptors, which are recognized during immune responses. The Immune Epitope Database and Analysis Resource (IEDB) project will catalog and organize information regarding antibody and T cell epitopes from infectious pathogens, experimental... | 2005-09-20 | Sathiamurthy, Muthuraman; Peters, Bjoern; Bui, Huynh-Hoa; Sidney, John; Mokili, John; Wilson, Stephen S; Fleri, Ward; McGuinness, Deborah L; Bourne, Philip E; Sette, Alessandro | Immunome Res | null | null | null | document_parses/pdf_json/ae19236936b05793ceac08ed5d58269c25486320.json | document_parses/pmc_json/PMC1287064.xml.json | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1287064/ | null |
1r65yam5 | 0a1533470817bc5ef0d0d0af56386a96b505dc0d | PMC | Evaluation of potential reference genes in real-time RT-PCR studies of Atlantic salmon | 10.1186/1471-2199-6-21 | PMC1314898 | 16,293,192 | cc-by | BACKGROUND: Salmonid fishes are among the most widely studied model fish species but reports on systematic evaluation of reference genes in qRT-PCR studies is lacking. RESULTS: The stability of six potential reference genes was examined in eight tissues of Atlantic salmon (Salmo salar), to determine the most suitable g... | 2005-11-17 | Olsvik, Pål A; Lie, Kai K; Jordal, Ann-Elise O; Nilsen, Tom O; Hordvik, Ivar | BMC Mol Biol | null | null | null | document_parses/pdf_json/0a1533470817bc5ef0d0d0af56386a96b505dc0d.json | document_parses/pmc_json/PMC1314898.xml.json | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1314898/ | null |
qva0jt86 | 4ba79e54ecf81b30b56461a6aec2094eaf7b7f06 | PMC | Relevance of human metapneumovirus in exacerbations of COPD | 10.1186/1465-9921-6-150 | PMC1334186 | 16,371,156 | cc-by | BACKGROUND AND METHODS: Human metapneumovirus (hMPV) is a recently discovered respiratory virus associated with bronchiolitis, pneumonia, croup and exacerbations of asthma. Since respiratory viruses are frequently detected in patients with acute exacerbations of COPD (AE-COPD) it was our aim to investigate the frequenc... | 2005-12-21 | Rohde, G; Borg, I; Arinir, U; Kronsbein, J; Rausse, R; Bauer, TT; Bufe, A; Schultze-Werninghaus, G | Respir Res | null | null | null | document_parses/pdf_json/4ba79e54ecf81b30b56461a6aec2094eaf7b7f06.json | document_parses/pmc_json/PMC1334186.xml.json | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1334186/ | null |
vw8xjo9t | c6202f96bd4b2aea699d5fbe867f311498dca3aa | PMC | Bioethical Implications of Globalization: An International Consortium Project of the European Commission | 10.1371/journal.pmed.0030043 | PMC1351155 | 16,420,098 | cc-by | The BIG project looks at some of the ethical concerns surrounding globalization and health. | 2006-01-24 | Novotny, Thomas E; Mordini, Emilio; Chadwick, Ruth; Pedersen, J. Martin; Fabbri, Fabrizio; Lie, Reidar; Thanachaiboot, Natapong; Mossialos, Elias; Permanand, Govin | PLoS Med | null | null | null | document_parses/pdf_json/c6202f96bd4b2aea699d5fbe867f311498dca3aa.json | document_parses/pmc_json/PMC1351155.xml.json | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1351155/ | null |
bnnl700a | a78fd1b34372e1e54bf2a192d04aa36670cea307 | PMC | Public awareness of risk factors for cancer among the Japanese general population: A population-based survey | 10.1186/1471-2458-6-2 | PMC1351169 | 16,403,223 | cc-by | BACKGROUND: The present study aimed to provide information on awareness of the attributable fraction of cancer causes among the Japanese general population. METHODS: A nationwide representative sample of 2,000 Japanese aged 20 or older was asked about their perception and level of concern about various environmental an... | 2006-01-10 | Inoue, Manami; Iwasaki, Motoki; Otani, Tetsuya; Sasazuki, Shizuka; Tsugane, Shoichiro | BMC Public Health | null | null | null | document_parses/pdf_json/a78fd1b34372e1e54bf2a192d04aa36670cea307.json | document_parses/pmc_json/PMC1351169.xml.json | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1351169/ | null |
m71xkuo9 | c6bf372c094f035a514975c35a7f9c094abbe493 | PMC | Sequence specific visual detection of LAMP reactions by addition of cationic polymers | 10.1186/1472-6750-6-3 | PMC1373654 | 16,401,354 | cc-by | BACKGROUND: Development of a practical gene point-of-care testing device (g-POCT device) requires innovative detection methods for demonstrating the results of the gene amplification reaction without the use of expensive equipment. We have studied a new method for the sequence-specific visual detection of minute amount... | 2006-01-10 | Mori, Yasuyoshi; Hirano, Tsuyoshi; Notomi, Tsugunori | BMC Biotechnol | null | null | null | document_parses/pdf_json/c6bf372c094f035a514975c35a7f9c094abbe493.json | document_parses/pmc_json/PMC1373654.xml.json | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1373654/ | null |
s64v656n | 1cafb8587a42557c4f96ed28b2dc5717ff54d20d | PMC | Injection drug use and HIV/AIDS in China: Review of current situation, prevention and policy implications | 10.1186/1477-7517-3-4 | PMC1402269 | 16,451,717 | cc-by | Illicit drug abuse and HIV/AIDS have increased rapidly in the past 10 to 20 years in China. This paper reviews drug abuse in China, the HIV/AIDS epidemic and its association with injection drug use (IDU), and Chinese policies on illicit drug abuse and prevention of HIV/AIDS based on published literature and unpublished... | 2006-02-01 | Qian, Han-Zhu; Schumacher, Joseph E; Chen, Huey T; Ruan, Yu-Hua | Harm Reduct J | null | null | null | document_parses/pdf_json/1cafb8587a42557c4f96ed28b2dc5717ff54d20d.json | document_parses/pmc_json/PMC1402269.xml.json | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1402269/ | null |
oluq7v0h | ccc36b04ad5c71de61967624f7f739e868d7c0a5 | PMC | Development of a humanized monoclonal antibody with therapeutic potential against West Nile virus | 10.1038/nm1240 | PMC1458527 | 15,852,016 | no-cc | Neutralization of West Nile virus (WNV) in vivo correlates with the development of an antibody response against the viral envelope (E) protein. Using random mutagenesis and yeast surface display, we defined individual contact residues of 14 newly generated monoclonal antibodies against domain III of the WNV E protein. ... | 2005-04-24 | Oliphant, Theodore; Engle, Michael; Nybakken, Grant E; Doane, Chris; Johnson, Syd; Huang, Ling; Gorlatov, Sergey; Mehlhop, Erin; Marri, Anantha; Chung, Kyung Min; Ebel, Gregory D; Kramer, Laura D; Fremont, Daved H; Diamond, Michael S | Nat Med | null | null | null | document_parses/pdf_json/ccc36b04ad5c71de61967624f7f739e868d7c0a5.json | document_parses/pmc_json/PMC1458527.xml.json | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1458527/ | null |
tw6wusxe | c8213638a9602d46f2f7ff6ba62b0df69beb0001 | PMC | Local public health workers' perceptions toward responding to an influenza pandemic | 10.1186/1471-2458-6-99 | PMC1459127 | 16,620,372 | cc-by | BACKGROUND: Current national preparedness plans require local health departments to play an integral role in responding to an influenza pandemic, a major public health threat that the World Health Organization has described as "inevitable and possibly imminent". To understand local public health workers' perceptions to... | 2006-04-18 | Balicer, Ran D; Omer, Saad B; Barnett, Daniel J; Everly, George S | BMC Public Health | null | null | null | document_parses/pdf_json/c8213638a9602d46f2f7ff6ba62b0df69beb0001.json | document_parses/pmc_json/PMC1459127.xml.json | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1459127/ | null |
58czem0j | a1b6c2b3b808e995697f94d9676d5d5c85180177 | PMC | On pandemics and the duty to care: whose duty? who cares? | 10.1186/1472-6939-7-5 | PMC1459179 | 16,626,488 | cc-by | BACKGROUND: As a number of commentators have noted, SARS exposed the vulnerabilities of our health care systems and governance structures. Health care professionals (HCPs) and hospital systems that bore the brunt of the SARS outbreak continue to struggle with the aftermath of the crisis. Indeed, HCPs – both in clinical... | 2006-04-20 | Ruderman, Carly; Tracy, C Shawn; Bensimon, Cécile M; Bernstein, Mark; Hawryluck, Laura; Shaul, Randi Zlotnik; Upshur, Ross EG | BMC Med Ethics | null | null | null | document_parses/pdf_json/a1b6c2b3b808e995697f94d9676d5d5c85180177.json | document_parses/pmc_json/PMC1459179.xml.json | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1459179/ | null |
x7wg7e9s | e7f311d3c752063f75f28de85abd5f82eacab413 | PMC | Epicatechins Purified from Green Tea (Camellia sinensis) Differentially Suppress Growth of Gender-Dependent Human Cancer Cell Lines | 10.1093/ecam/nel003 | PMC1475929 | 16,786,054 | no-cc | The anticancer potential of catechins derived from green tea is not well understood, in part because catechin-related growth suppression and/or apoptosis appears to vary with the type and stage of malignancy as well as with the type of catechin. This in vitro study examined the biological effects of epicatechin (EC), e... | 2006-04-25 | Ravindranath, Mepur H.; Saravanan, Thiruverkadu S.; Monteclaro, Clarence C.; Presser, Naftali; Ye, Xing; Selvan, Senthamil R.; Brosman, Stanley | Evid Based Complement Alternat Med | null | null | null | document_parses/pdf_json/e7f311d3c752063f75f28de85abd5f82eacab413.json | document_parses/pmc_json/PMC1475929.xml.json | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1475929/ | null |
utglk4af | babad3896fca8ed7c89d9b785c08e7c42a48a6a2 | PMC | Markers of exacerbation severity in chronic obstructive pulmonary disease | 10.1186/1465-9921-7-74 | PMC1481583 | 16,686,949 | cc-by | BACKGROUND: Patients with chronic obstructive pulmonary disease (COPD) can experience 'exacerbations' of their conditions. An exacerbation is an event defined in terms of subjective descriptors or symptoms, namely dyspnoea, cough and sputum that worsen sufficiently to warrant a change in medical management. There is a ... | 2006-05-10 | Franciosi, Luigi G; Page, Clive P; Celli, Bartolome R; Cazzola, Mario; Walker, Michael J; Danhof, Meindert; Rabe, Klaus F; Pasqua, Oscar E Della | Respir Res | null | null | null | document_parses/pdf_json/babad3896fca8ed7c89d9b785c08e7c42a48a6a2.json | document_parses/pmc_json/PMC1481583.xml.json | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1481583/ | null |
i5fcedbo | null | PMC | Scientific Abstracts | 10.1111/j.1525-1497.2006.00469.x | PMC1484878 | 17,703,327 | no-cc | null | 2006-04-03 | null | J Gen Intern Med | null | null | null | null | null | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1484878/ | null |
bjjft7ut | null | PMC | Society of General Internal Medicine: 28th Annual Meeting New Orleans, LA May 11–14, 2005: Out of Chaos: The Critical Role of Generalists, ABSTRACTS OF SUBMISSIONS ACCEPTED FOR PRESENTATIOIN | 10.1111/j.1525-1497.2005.020s1.x | PMC1490295 | 15,842,728 | no-cc | null | 2005-04-03 | null | J Gen Intern Med | null | null | null | null | null | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1490295/ | null |
urk7fe34 | null | PMC | CLINICAL VIGNETTES | 10.1111/j.1525-1497.2004.s1006_1.x | PMC1492602 | 15,107,043 | no-cc | null | 2004-04-03 | null | J Gen Intern Med | null | null | null | null | null | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1492602/ | null |
1a3sy8ja | a037a1a6fe76f1c43e33a639231b9874cb655f88 | PMC | CLINICAL VIGNETTES | 10.1046/j.1525-1497.18.s1.20.x | PMC1494988 | 12,753,119 | no-cc | null | 2003-04-03 | null | J Gen Intern Med | null | null | null | document_parses/pdf_json/a037a1a6fe76f1c43e33a639231b9874cb655f88.json | null | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1494988/ | null |
u09rn09u | null | PMC | ABSTRACTS | 10.1046/j.1525-1497.17.s1.9.x | PMC1495151 | 11,972,737 | no-cc | null | 2002-04-03 | null | J Gen Intern Med | null | null | null | null | null | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1495151/ | null |
kvztcwu2 | 38c0691ee76fb1e6642b4b33ade445bcbb0e1424 | PMC | Clinical Vignettes | 10.1046/j.1525-1497.2001.0160s1023.x | PMC1495316 | 11,357,836 | no-cc | null | 2001-04-03 | null | J Gen Intern Med | null | null | null | document_parses/pdf_json/38c0691ee76fb1e6642b4b33ade445bcbb0e1424.json | null | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1495316/ | null |
9r62ffew | 4db3931c4b24ae432d68b7e24f593b1272445523 | PMC | Differentially profiling the low-expression transcriptomes of human hepatoma using a novel SSH/microarray approach | 10.1186/1471-2164-7-131 | PMC1522022 | 16,737,534 | cc-by | BACKGROUND: The main limitation in performing genome-wide gene-expression profiling is the assay of low-expression genes. Approaches with high throughput and high sensitivity for assaying low-expression transcripts are urgently needed for functional genomic studies. Combination of the suppressive subtractive hybridizat... | 2006-05-31 | Pan, Yi-Shin; Lee, Yun-Shien; Lee, Yung-Lin; Lee, Wei-Chen; Hsieh, Sen-Yung | BMC Genomics | null | null | null | document_parses/pdf_json/4db3931c4b24ae432d68b7e24f593b1272445523.json | document_parses/pmc_json/PMC1522022.xml.json | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1522022/ | null |
d3cko4j2 | 40500cd7ae5b4e116e8b13e5408e7dfd96d43ab4 | PMC | From Functional Genomics to Functional Immunomics: New Challenges, Old Problems, Big Rewards | 10.1371/journal.pcbi.0020081 | PMC1523295 | 16,863,395 | cc-by | The development of DNA microarray technology a decade ago led to the establishment of functional genomics as one of the most active and successful scientific disciplines today. With the ongoing development of immunomic microarray technology—a spatially addressable, large-scale technology for measurement of specific imm... | 2006-07-28 | Braga-Neto, Ulisses M; Marques, Ernesto T. A | PLoS Comput Biol | null | null | null | document_parses/pdf_json/40500cd7ae5b4e116e8b13e5408e7dfd96d43ab4.json | document_parses/pmc_json/PMC1523295.xml.json | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1523295/ | null |
hwlvk68z | 0dcf7336a3569d4103dc5be47ddd6b583dea98f0 | PMC | Transmission patterns of smallpox: systematic review of natural outbreaks in Europe and North America since World War II | 10.1186/1471-2458-6-126 | PMC1525174 | 16,677,388 | cc-by | BACKGROUND: Because smallpox (variola major) may be used as a biological weapon, we reviewed outbreaks in post-World War II Europe and North America in order to understand smallpox transmission patterns. METHODS: A systematic review was used to identify papers from the National Library of Medicine, Embase, Biosis, Coch... | 2006-05-05 | Bhatnagar, Vibha; Stoto, Michael A; Morton, Sally C; Boer, Rob; Bozzette, Samuel A | BMC Public Health | null | null | null | document_parses/pdf_json/0dcf7336a3569d4103dc5be47ddd6b583dea98f0.json | document_parses/pmc_json/PMC1525174.xml.json | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1525174/ | null |
w5fxen70 | 6cfcbd2a102a3666d0d168f9bdaba0b2107fc8bd | PMC | Reliability of case definitions for public health surveillance assessed by Round-Robin test methodology | 10.1186/1471-2458-6-129 | PMC1538585 | 16,686,946 | cc-by | BACKGROUND: Case definitions have been recognized to be important elements of public health surveillance systems. They are to assure comparability and consistency of surveillance data and have crucial impact on the sensitivity and the positive predictive value of a surveillance system. The reliability of case definitio... | 2006-05-10 | Krause, Gérard; Brodhun, Bonita; Altmann, Doris; Claus, Hermann; Benzler, Justus | BMC Public Health | null | null | null | document_parses/pdf_json/6cfcbd2a102a3666d0d168f9bdaba0b2107fc8bd.json | document_parses/pmc_json/PMC1538585.xml.json | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1538585/ | null |
mq6bterc | 575e5af469e1a43638c3dac9fdafda882fbe9d7a | PMC | Ventilator associated pneumonia and infection control | 10.1186/1476-0711-5-7 | PMC1540438 | 16,600,048 | cc-by | Ventilator associated pneumonia (VAP) is the leading cause of morbidity and mortality in intensive care units. The incidence of VAP varies from 7% to 70% in different studies and the mortality rates are 20–75% according to the study population. Aspiration of colonized pathogenic microorganisms on the oropharynx and gas... | 2006-04-06 | Alp, Emine; Voss, Andreas | Ann Clin Microbiol Antimicrob | null | null | null | document_parses/pdf_json/575e5af469e1a43638c3dac9fdafda882fbe9d7a.json | document_parses/pmc_json/PMC1540438.xml.json | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1540438/ | null |
yxhk1qm3 | 6bbbd25c11b320bdd509a9c76417ed4045349708 | PMC | Sentinel surveillance for human enterovirus 71 in Sarawak, Malaysia: lessons from the first 7 years | 10.1186/1471-2458-6-180 | PMC1543637 | 16,827,926 | cc-by | BACKGROUND: A major outbreak of human enterovirus 71-associated hand, foot and mouth disease in Sarawak in 1997 marked the beginning of a series of outbreaks in the Asia Pacific region. Some of these outbreaks had unusually high numbers of fatalities and this generated much fear and anxiety in the region. METHODS: We e... | 2006-07-07 | Podin, Yuwana; Gias, Edna LM; Ong, Flora; Leong, Yee-Wei; Yee, Siew-Fung; Yusof, Mohd Apandi; Perera, David; Teo, Bibiana; Wee, Thian-Yew; Yao, Sik-Chi; Yao, Sik-King; Kiyu, Andrew; Arif, Mohd Taha; Cardosa, Mary Jane | BMC Public Health | null | null | null | document_parses/pdf_json/6bbbd25c11b320bdd509a9c76417ed4045349708.json | document_parses/pmc_json/PMC1543637.xml.json | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1543637/ | null |
bpnfupzv | null | PMC | 26th International Symposium on Intensive Care and Emergency Medicine, 21–24 March 2006, Brussels, Belgium | 10.1186/cc4935 | PMC1550926 | 16,732,901 | no-cc | null | 2006-05-18 | Wurz, Jeannie | Crit Care | null | null | null | null | null | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1550926/ | null |
j3p1u80n | 4c84dbfd01f7b2009ebed54376da8afcbcf1ec64 | PMC | Model-Based Design of Growth-Attenuated Viruses | 10.1371/journal.pcbi.0020116 | PMC1557587 | 16,948,530 | cc-by | Live-virus vaccines activate both humoral and cell-mediated immunity, require only a single boosting, and generally provide longer immune protection than killed or subunit vaccines. However, growth of live-virus vaccines must be attenuated to minimize their potential pathogenic effects, and mechanisms of attenuation by... | 2006-09-01 | Lim, Kwang-il; Lang, Tobias; Lam, Vy; Yin, John | PLoS Comput Biol | null | null | null | document_parses/pdf_json/4c84dbfd01f7b2009ebed54376da8afcbcf1ec64.json | document_parses/pmc_json/PMC1557587.xml.json | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1557587/ | null |
5eqdrd52 | f4d18f2beafa875cd4e30a9a237a64b9d3110856 | PMC | Delivery Systems for the Direct Application of siRNAs to Induce RNA Interference (RNAi) In Vivo | 10.1155/jbb/2006/71659 | PMC1559929 | 17,057,369 | no-cc | RNA interference (RNAi) is a powerful method for specific gene silencing which may also lead to promising novel therapeutic strategies. It is mediated through small interfering RNAs (siRNAs) which sequence-specifically trigger the cleavage and subsequent degradation of their target mRNA. One critical factor is the abil... | 2006-05-18 | Aigner, Achim | J Biomed Biotechnol | null | null | null | document_parses/pdf_json/f4d18f2beafa875cd4e30a9a237a64b9d3110856.json | document_parses/pmc_json/PMC1559929.xml.json | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1559929/ | null |
p5jtwb3l | null | PMC | Electrochemical Molecular Analysis Without Nucleic Acid Amplification | 10.1016/j.ymeth.2005.05.008 | PMC1564062 | 16,213,156 | green-oa | Electrochemical biosensors have revolutionized glucose monitoring but have not yet fulfilled their promise of a low cost, direct detection replacement for genetic amplification tests such as PCR [K. Kerman, M. Kobayashi, E. Tamiya, Recent trends in electro-chemical DNA biosensor technology, Meas. Sci. Technol. 15 (2004... | 2005-09-01 | Gau, Vincent; Ma, Shu-Ching; Wang, Hua; Tsukuda, Joni; Kibler, John; Haake, David A. | Methods | null | null | null | null | document_parses/pmc_json/PMC1564062.xml.json | http://europepmc.org/articles/pmc1564062?pdf=render | null |
c5hrdrtu | 94be6e5f47cbef1a762c2cb3c1f37d4862b53403 | PMC | Identification of new participants in the rainbow trout (Oncorhynchus mykiss) oocyte maturation and ovulation processes using cDNA microarrays | 10.1186/1477-7827-4-39 | PMC1570352 | 16,872,517 | cc-by | BACKGROUND: The hormonal control of oocyte maturation and ovulation as well as the molecular mechanisms of nuclear maturation have been thoroughly studied in fish. In contrast, the other molecular events occurring in the ovary during post-vitellogenesis have received far less attention. METHODS: Nylon microarrays displ... | 2006-07-27 | Bobe, Julien; Montfort, Jerôme; Nguyen, Thaovi; Fostier, Alexis | Reprod Biol Endocrinol | null | null | null | document_parses/pdf_json/94be6e5f47cbef1a762c2cb3c1f37d4862b53403.json | document_parses/pmc_json/PMC1570352.xml.json | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1570352/ | null |
pk7pnmlo | 61d9a0fe39f4e845c44a06787de6f5f033b998a3 | PMC | An object simulation model for modeling hypothetical disease epidemics – EpiFlex | 10.1186/1742-4682-3-32 | PMC1570461 | 16,928,271 | cc-by | BACKGROUND: EpiFlex is a flexible, easy to use computer model for a single computer, intended to be operated by one user who need not be an expert. Its purpose is to study in-silico the epidemic behavior of a wide variety of diseases, both known and theoretical, by simulating their spread at the level of individuals co... | 2006-08-23 | Hanley, Brian | Theor Biol Med Model | null | null | null | document_parses/pdf_json/61d9a0fe39f4e845c44a06787de6f5f033b998a3.json | document_parses/pmc_json/PMC1570461.xml.json | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1570461/ | null |
nhb4o6ty | 315e5980d6fdce4553a9df8c0e36e55ffed32365 | PMC | Multiplexed Genetic Analysis Using an Expanded Genetic Alphabet | 10.1373/clinchem.2004.034330 | PMC1592527 | 15,319,316 | bronze-oa | BACKGROUND: All states require some kind of testing for newborns, but the policies are far from standardized. In some states, newborn screening may include genetic tests for a wide range of targets, but the costs and complexities of the newer genetic tests inhibit expansion of newborn screening. We describe the develop... | 2004-11-01 | Johnson, Scott C.; Marshall, David J.; Harms, Gerda; Miller, Christie M.; Sherrill, Christopher B.; Beaty, Edward L.; Lederer, Scott A.; Roesch, Eric B.; Madsen, Gary; Hoffman, Gary L.; Laessig, Ronald H.; Kopish, Greg J.; Baker, Mei Wang; Benner, Steven A.; Farrell, Philip M.; Prudent, James R. | Clinical Chemistry | null | null | null | document_parses/pdf_json/315e5980d6fdce4553a9df8c0e36e55ffed32365.json | document_parses/pmc_json/PMC1592527.xml.json | http://clinchem.aaccjnls.org/content/clinchem/50/11/2019.full.pdf | null |
xgwbl8em | c1ad13d83e926979dbf2bbe52e4944082f28dfea | PMC | Antisense-induced ribosomal frameshifting | 10.1093/nar/gkl531 | PMC1616946 | 16,920,740 | cc-by-nc | Programmed ribosomal frameshifting provides a mechanism to decode information located in two overlapping reading frames by diverting a proportion of translating ribosomes into a second open reading frame (ORF). The result is the production of two proteins: the product of standard translation from ORF1 and an ORF1–ORF2 ... | 2006-08-18 | Henderson, Clark M.; Anderson, Christine B.; Howard, Michael T. | Nucleic Acids Res | null | null | null | document_parses/pdf_json/c1ad13d83e926979dbf2bbe52e4944082f28dfea.json | document_parses/pmc_json/PMC1616946.xml.json | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1616946/ | null |
69gftii4 | 25fd0362dfe0a62ca9ee6f9f634e24ef9a527dfc | PMC | The gene of an archaeal α-l-fucosidase is expressed by translational frameshifting | 10.1093/nar/gkl574 | PMC1616953 | 16,920,738 | cc-by-nc | The standard rules of genetic translational decoding are altered in specific genes by different events that are globally termed recoding. In Archaea recoding has been unequivocally determined so far only for termination codon readthrough events. We study here the mechanism of expression of a gene encoding for a α-l-fuc... | 2006-08-18 | Cobucci-Ponzano, Beatrice; Conte, Fiorella; Benelli, Dario; Londei, Paola; Flagiello, Angela; Monti, Maria; Pucci, Piero; Rossi, Mosè; Moracci, Marco | Nucleic Acids Res | null | null | null | document_parses/pdf_json/25fd0362dfe0a62ca9ee6f9f634e24ef9a527dfc.json | document_parses/pmc_json/PMC1616953.xml.json | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1616953/ | null |
vefs1h6o | d230ca9dcc54e1d5c0ed4503752774eb44711dff | PMC | Role of RNA helicases in HIV-1 replication | 10.1093/nar/gkl398 | PMC1616970 | 16,935,887 | cc-by-nc | Viruses are replication competent genomes which are relatively gene-poor. Even the largest viruses (i.e. Herpesviruses) encode only slightly >200 open reading frames (ORFs). However, because viruses replicate obligatorily inside cells, and considering that evolution may be driven by a principle of economy of scale, it ... | 2006-08-25 | Jeang, Kuan-Teh; Yedavalli, Venkat | Nucleic Acids Res | null | null | null | document_parses/pdf_json/d230ca9dcc54e1d5c0ed4503752774eb44711dff.json | document_parses/pmc_json/PMC1616970.xml.json | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1616970/ | null |
1ypgij14 | bdcfff55eaabeaa26d71810113d717ef85e417d1 | PMC | MIMOX: a web tool for phage display based epitope mapping | 10.1186/1471-2105-7-451 | PMC1618411 | 17,038,191 | cc-by | BACKGROUND: Phage display is widely used in basic research such as the exploration of protein-protein interaction sites and networks, and applied research such as the development of new drugs, vaccines, and diagnostics. It has also become a promising method for epitope mapping. Research on new algorithms that assist an... | 2006-10-12 | Huang, Jian; Gutteridge, Alex; Honda, Wataru; Kanehisa, Minoru | BMC Bioinformatics | null | null | null | document_parses/pdf_json/bdcfff55eaabeaa26d71810113d717ef85e417d1.json | document_parses/pmc_json/PMC1618411.xml.json | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1618411/ | null |
1axxmq84 | d90d787828b6f96b4a93eb6948d613293bc51bf9 | PMC | Endogenous Cell Repair of Chronic Demyelination | 10.1097/01.jnen.0000205142.08716.7e | PMC1635791 | 16,651,886 | bronze-oa | In multiple sclerosis lesions, remyelination typically fails with repeated or chronic demyelinating episodes and results in neurologic disability. Acute demyelination models in rodents typically exhibit robust spontaneous remyelination that prevents appropriate evaluation of strategies for improving conditions of insuf... | 2006-03-01 | Armstrong, Regina C.; Le, Tuan Q.; Flint, Nicole C.; Vana, Adam C.; Zhou, Yong-Xing | Journal of Neuropathology and Experimental Neurology | null | null | null | document_parses/pdf_json/d90d787828b6f96b4a93eb6948d613293bc51bf9.json | document_parses/pmc_json/PMC1635791.xml.json | https://academic.oup.com/jnen/article-pdf/65/3/245/8276837/65-3-245.pdf | null |
cxzlmfst | 4eb6e165ee705e2ae2a24ed2d4e67da42831ff4a; d4f0247db5e916c20eae3f6d772e8572eb828236 | PMC | Automated identification of multiple micro-organisms from resequencing DNA microarrays | 10.1093/nar/gkl565 | PMC1636417 | 17,012,284 | cc-by-nc | There is an increasing recognition that detailed nucleic acid sequence information will be useful and even required in the diagnosis, treatment and surveillance of many significant pathogens. Because generating detailed information about pathogens leads to significantly larger amounts of data, it is necessary to develo... | 2006-09-29 | Malanoski, Anthony P.; Lin, Baochuan; Wang, Zheng; Schnur, Joel M.; Stenger, David A. | Nucleic Acids Res | null | null | null | document_parses/pdf_json/4eb6e165ee705e2ae2a24ed2d4e67da42831ff4a.json; document_parses/pdf_json/d4f0247db5e916c20eae3f6d772e8572eb828236.json | document_parses/pmc_json/PMC1636417.xml.json | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1636417/ | null |
br2p09pg | ad9ac0ac5e7da097253fd545b56e2b15ee9de34f; daee7f7d31f4bf1c0ef883bcd6c124b6e94cbee7 | PMC | Molecular dynamics simulations of human [Formula: see text]: the role of modified bases in mRNA recognition | 10.1093/nar/gkl580 | PMC1636460 | 17,012,271 | cc-by-nc | Accuracy in translation of the genetic code into proteins depends upon correct tRNA–mRNA recognition in the context of the ribosome. In human [Formula: see text] three modified bases are present in the anticodon stem–loop—2-methylthio-N6-threonylcarbamoyladenosine at position 37 (ms(2)t(6)A37), 5-methoxycarbonylmethyl-... | 2006-09-29 | McCrate, Nina E.; Varner, Mychel E.; Kim, Kenneth I.; Nagan, Maria C. | Nucleic Acids Res | null | null | null | document_parses/pdf_json/ad9ac0ac5e7da097253fd545b56e2b15ee9de34f.json; document_parses/pdf_json/daee7f7d31f4bf1c0ef883bcd6c124b6e94cbee7.json | document_parses/pmc_json/PMC1636460.xml.json | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1636460/ | null |
kt9pmfdr | 52566dccb4bd8044edc87b1a0aa268320a6ea3d4; 8b39433dd865c0f71c7b2f333e1f506b73d722f1 | PMC | A novel endonuclease IV post-PCR genotyping system | 10.1093/nar/gkl679 | PMC1636472 | 17,012,270 | cc-by-nc | Here we describe a novel endonuclease IV (Endo IV) based assay utilizing a substrate that mimics the abasic lesions that normally occur in double-stranded DNA. The three component substrate is characterized by single-stranded DNA target, an oligonucleotide probe, separated from a helper oligonucleotide by a one base ga... | 2006-09-29 | Kutyavin, Igor V.; Milesi, Dave; Belousov, Yevgeniy; Podyminogin, Mikhail; Vorobiev, Alexei; Gorn, Vladimir; Lukhtanov, Eugeny A.; Vermeulen, Nicolaas M. J.; Mahoney, Walt | Nucleic Acids Res | null | null | null | document_parses/pdf_json/52566dccb4bd8044edc87b1a0aa268320a6ea3d4.json; document_parses/pdf_json/8b39433dd865c0f71c7b2f333e1f506b73d722f1.json | document_parses/pmc_json/PMC1636472.xml.json | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1636472/ | null |
5fl0rk90 | 12de3563e18c3c6c5943fa8216e0eea970a590cd | PMC | Pandemic influenza preparedness: an ethical framework to guide decision-making | 10.1186/1472-6939-7-12 | PMC1698926 | 17,144,926 | cc-by | BACKGROUND: Planning for the next pandemic influenza outbreak is underway in hospitals across the world. The global SARS experience has taught us that ethical frameworks to guide decision-making may help to reduce collateral damage and increase trust and solidarity within and between health care organisations. Good pan... | 2006-12-04 | Thompson, Alison K; Faith, Karen; Gibson, Jennifer L; Upshur, Ross EG | BMC Med Ethics | null | null | null | document_parses/pdf_json/12de3563e18c3c6c5943fa8216e0eea970a590cd.json | document_parses/pmc_json/PMC1698926.xml.json | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1698926/ | null |
kuf3ssdb | c0f8a4eef924cdeeeb5b17ae685760bf7cce9223 | PMC | Open lung biopsy in early-stage acute respiratory distress syndrome | 10.1186/cc4981 | PMC1751007 | 16,859,510 | cc-by | INTRODUCTION: Acute respiratory distress syndrome (ARDS) has heterogeneous etiologies, rapid progressive change and a high mortality rate. To improve the outcome of ARDS, accurate diagnosis is essential to the application of effective early treatment. The present study investigated the clinical effects and safety of op... | 2006-07-19 | Kao, Kuo-Chin; Tsai, Ying-Huang; Wu, Yao-Kuang; Chen, Ning-Hung; Hsieh, Meng-Jer; Huang, Shiu-Feng; Huang, Chung-Chi | Crit Care | null | null | null | document_parses/pdf_json/c0f8a4eef924cdeeeb5b17ae685760bf7cce9223.json | document_parses/pmc_json/PMC1751007.xml.json | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1751007/ | null |
rr2wwvue | c64f525d77bf8b2ae4439a875f1bd8eb197a0519 | PMC | Association and Host Selectivity in Multi-Host Pathogens | 10.1371/journal.pone.0000041 | PMC1762347 | 17,183,670 | cc-by | The distribution of multi-host pathogens over their host range conditions their population dynamics and structure. Also, host co-infection by different pathogens may have important consequences for the evolution of hosts and pathogens, and host-pathogen co-evolution. Hence it is of interest to know if the distribution ... | 2006-12-20 | Malpica, José M.; Sacristán, Soledad; Fraile, Aurora; García-Arenal, Fernando | PLoS One | null | null | null | document_parses/pdf_json/c64f525d77bf8b2ae4439a875f1bd8eb197a0519.json | document_parses/pmc_json/PMC1762347.xml.json | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1762347/ | null |
1n0rg5vd | 6af02873a430f5f75dc56a917f26feaea89b8e79 | PMC | The Effectiveness of Contact Tracing in Emerging Epidemics | 10.1371/journal.pone.0000012 | PMC1762362 | 17,183,638 | cc-by | BACKGROUND: Contact tracing plays an important role in the control of emerging infectious diseases, but little is known yet about its effectiveness. Here we deduce from a generic mathematical model how effectiveness of tracing relates to various aspects of time, such as the course of individual infectivity, the (variab... | 2006-12-20 | Klinkenberg, Don; Fraser, Christophe; Heesterbeek, Hans | PLoS One | null | null | null | document_parses/pdf_json/6af02873a430f5f75dc56a917f26feaea89b8e79.json | document_parses/pmc_json/PMC1762362.xml.json | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1762362/ | null |
nzh87aux | 9b7a0ad7b6c7f59e7a6cf1dc9d07912a273d19b5 | PMC | The Waiting Time for Inter-Country Spread of Pandemic Influenza | 10.1371/journal.pone.0000143 | PMC1764036 | 17,206,278 | cc-by | BACKGROUND: The time delay between the start of an influenza pandemic and its subsequent initiation in other countries is highly relevant to preparedness planning. We quantify the distribution of this random time in terms of the separate components of this delay, and assess how the delay may be extended by non-pharmace... | 2007-01-03 | Caley, Peter; Becker, Niels G.; Philp, David J. | PLoS One | null | null | null | document_parses/pdf_json/9b7a0ad7b6c7f59e7a6cf1dc9d07912a273d19b5.json | document_parses/pmc_json/PMC1764036.xml.json | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1764036/ | null |
1y5nej0m | b6353f8b0fcd86c2fd1e6f27c9b18a3ccc07980b | PMC | Neutralizing Antibody Fails to Impact the Course of Ebola Virus Infection in Monkeys | 10.1371/journal.ppat.0030009 | PMC1779296 | 17,238,286 | cc0 | Prophylaxis with high doses of neutralizing antibody typically offers protection against challenge with viruses producing acute infections. In this study, we have investigated the ability of the neutralizing human monoclonal antibody, KZ52, to protect against Ebola virus in rhesus macaques. This antibody was previously... | 2007-01-19 | Oswald, Wendelien B; Geisbert, Thomas W; Davis, Kelly J; Geisbert, Joan B; Sullivan, Nancy J; Jahrling, Peter B; Parren, Paul W. H. I; Burton, Dennis R | PLoS Pathog | null | null | null | document_parses/pdf_json/b6353f8b0fcd86c2fd1e6f27c9b18a3ccc07980b.json | document_parses/pmc_json/PMC1779296.xml.json | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1779296/ | null |
fvfjz7al | 53dbd21da3e3a026ab15e946639b45970d6304de | PMC | Public health preparedness in Alberta: a systems-level study | 10.1186/1471-2458-6-313 | PMC1779785 | 17,194,305 | cc-by | BACKGROUND: Recent international and national events have brought critical attention to the Canadian public health system and how prepared the system is to respond to various types of contemporary public health threats. This article describes the study design and methods being used to conduct a systems-level analysis o... | 2006-12-28 | Moore, Douglas; Shiell, Alan; Noseworthy, Tom; Russell, Margaret; Predy, Gerald | BMC Public Health | null | null | null | document_parses/pdf_json/53dbd21da3e3a026ab15e946639b45970d6304de.json | document_parses/pmc_json/PMC1779785.xml.json | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1779785/ | null |
lntn11a9 | 9795fe49f827ff0654ce919cd8b7450e8a2b40d8 | PMC | The immunoregulatory and allergy-associated cytokines in the aetiology of the otitis media with effusion. | 10.1080/09629350410001688477 | PMC1781541 | 15,203,548 | no-cc | Inflammation in the middle ear mucosa, which can be provoked by different primary factors such as bacterial and viral infection, local allergic reactions and reflux, is the crucial event in the pathogenesis of otitis media with effusion (OME). Unresolved acute inflammatory responses or defective immunoregulation of mid... | 2004-04-03 | Smirnova, Marina G; Birchall, John P; Pearson, Jeffrey P | Mediators Inflamm | null | null | null | document_parses/pdf_json/9795fe49f827ff0654ce919cd8b7450e8a2b40d8.json | null | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1781541/ | null |
nzk8m912 | b3ab47699907f78c2ac478d06f682f56fa0cf351 | PMC | Bench-to-bedside review: Critical illness-associated cognitive dysfunction – mechanisms, markers, and emerging therapeutics | 10.1186/cc5078 | PMC1794449 | 17,118,217 | no-cc | Cognitive dysfunction is common in critically ill patients, not only during the acute illness but also long after its resolution. A large number of pathophysiologic mechanisms are thought to underlie critical illness-associated cognitive dysfunction, including neuro-transmitter abnormalities and occult diffuse brain in... | 2006-11-15 | Milbrandt, Eric B; Angus, Derek C | Crit Care | null | null | null | document_parses/pdf_json/b3ab47699907f78c2ac478d06f682f56fa0cf351.json | document_parses/pmc_json/PMC1794449.xml.json | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1794449/ | null |
ps3mnpzq | c34dcfec2a5e68f31f6a0401d2cd636021d984bc | PMC | ProCAT: a data analysis approach for protein microarrays | 10.1186/gb-2006-7-11-r110 | PMC1794587 | 17,109,749 | cc-by | Protein microarrays provide a versatile method for the analysis of many protein biochemical activities. Existing DNA microarray analytical methods do not translate to protein microarrays due to differences between the technologies. Here we report a new approach, ProCAT, which corrects for background bias and spatial ar... | 2006-11-16 | Zhu, Xiaowei; Gerstein, Mark; Snyder, Michael | Genome Biol | null | null | null | document_parses/pdf_json/c34dcfec2a5e68f31f6a0401d2cd636021d984bc.json | document_parses/pmc_json/PMC1794587.xml.json | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1794587/ | null |
m56agj4z | b0a0f45be3069a32ba190502ab88b6df6d520199 | PMC | Positional clustering improves computational binding site detection and identifies novel cis-regulatory sites in mammalian GABA(A) receptor subunit genes | 10.1093/nar/gkl1062 | PMC1807961 | 17,204,484 | cc-by-nc | Understanding transcription factor (TF) mediated control of gene expression remains a major challenge at the interface of computational and experimental biology. Computational techniques predicting TF-binding site specificity are frequently unreliable. On the other hand, comprehensive experimental validation is difficu... | 2007-01-03 | Reddy, Timothy E.; Shakhnovich, Boris E.; Roberts, Daniel S.; Russek, Shelley J.; DeLisi, Charles | Nucleic Acids Res | null | null | null | document_parses/pdf_json/b0a0f45be3069a32ba190502ab88b6df6d520199.json | document_parses/pmc_json/PMC1807961.xml.json | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1807961/ | null |
x2zq0lnt | d882f79283751d6c7f2e48cb991ee8abbcd913ae | PMC | The Transmissibility of Highly Pathogenic Avian Influenza in Commercial Poultry in Industrialised Countries | 10.1371/journal.pone.0000349 | PMC1831494 | 17,406,673 | cc-by | BACKGROUND: With the increased occurrence of outbreaks of H5N1 worldwide there is concern that the virus could enter commercial poultry farms with severe economic consequences. METHODOLOGY/PRINCIPAL FINDINGS: We analyse data from four recent outbreaks of highly pathogenic avian influenza (HPAI) in commercial poultry to... | 2007-04-04 | Garske, Tini; Clarke, Paul; Ghani, Azra C. | PLoS One | null | null | null | document_parses/pdf_json/d882f79283751d6c7f2e48cb991ee8abbcd913ae.json | document_parses/pmc_json/PMC1831494.xml.json | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1831494/ | null |
hf3nytb2 | f3f471d10a36a7a28e9050c10bd4dfd680cba17b | PMC | The influenza pandemic preparedness planning tool InfluSim | 10.1186/1471-2334-7-17 | PMC1832202 | 17,355,639 | cc-by | BACKGROUND: Planning public health responses against pandemic influenza relies on predictive models by which the impact of different intervention strategies can be evaluated. Research has to date rather focused on producing predictions for certain localities or under specific conditions, than on designing a publicly av... | 2007-03-13 | Eichner, Martin; Schwehm, Markus; Duerr, Hans-Peter; Brockmann, Stefan O | BMC Infect Dis | null | null | null | document_parses/pdf_json/f3f471d10a36a7a28e9050c10bd4dfd680cba17b.json | document_parses/pmc_json/PMC1832202.xml.json | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1832202/ | null |
byp2eqhd | 323ece9056ef7a1d81faf3422e98def1efd38f70 | PMC | Immune pathways and defence mechanisms in honey bees Apis mellifera | 10.1111/j.1365-2583.2006.00682.x | PMC1847501 | 17,069,638 | no-cc | Social insects are able to mount both group-level and individual defences against pathogens. Here we focus on individual defences, by presenting a genome-wide analysis of immunity in a social insect, the honey bee Apis mellifera. We present honey bee models for each of four signalling pathways associated with immunity,... | 2006-10-01 | Evans, J D; Aronstein, K; Chen, Y P; Hetru, C; Imler, J-L; Jiang, H; Kanost, M; Thompson, G J; Zou, Z; Hultmark, D | Insect Mol Biol | null | null | null | document_parses/pdf_json/323ece9056ef7a1d81faf3422e98def1efd38f70.json | document_parses/pmc_json/PMC1847501.xml.json | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1847501/ | null |
s4y6uxsb | 305cf1019ca9c81126b2e527fedf79969c2c522f | PMC | ElaD, a Deubiquitinating Protease Expressed by E. coli | 10.1371/journal.pone.0000381 | PMC1847702 | 17,440,617 | cc-by | BACKGROUND: Ubiquitin and ubiquitin-like proteins (Ubl) are designed to modify polypeptides in eukaryotes. Covalent binding of ubiquitin or Ubls to substrate proteins can be reversed by specific hydrolases. One particular set of cysteine proteases, the CE clan, which targets ubiquitin and Ubls, has homologs in eukaryot... | 2007-04-18 | Catic, André; Misaghi, Shahram; Korbel, Gregory A.; Ploegh, Hidde L. | PLoS One | null | null | null | document_parses/pdf_json/305cf1019ca9c81126b2e527fedf79969c2c522f.json | document_parses/pmc_json/PMC1847702.xml.json | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1847702/ | null |
9zmyojbu | 6ea2532aacbdcea4609067523e9e72fa8cd73200 | PMC | Mutational analysis of human CEACAM1: the potential of receptor polymorphism in increasing host susceptibility to bacterial infection | 10.1111/j.1462-5822.2006.00789.x | PMC1859983 | 16,953,805 | no-cc | A common overlapping site on the N-terminal IgV-like domain of human carcinoembryonic antigen (CEA)-related cell adhesion molecules (CEACAMs) is targeted by several important human respiratory pathogens. These include Neisseria meningitidis (Nm) and Haemophilus influenzae (Hi) that can cause disseminated or persistent ... | 2007-02-01 | Villullas, Silvia; Hill, Darryl J; Sessions, Richard B; Rea, Jon; Virji, Mumtaz | Cell Microbiol | null | null | null | document_parses/pdf_json/6ea2532aacbdcea4609067523e9e72fa8cd73200.json | document_parses/pmc_json/PMC1859983.xml.json | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1859983/ | null |
4y8ghcpq | e148597ac3bd53fe2dd4fa4fc6677502fc8da423 | PMC | Immune reconstitution inflammatory syndrome (IRIS): review of common infectious manifestations and treatment options | 10.1186/1742-6405-4-9 | PMC1871602 | 17,488,505 | cc-by | The immune reconstitution inflammatory syndrome (IRIS) in HIV-infected patients initiating antiretroviral therapy (ART) results from restored immunity to specific infectious or non-infectious antigens. A paradoxical clinical worsening of a known condition or the appearance of a new condition after initiating therapy ch... | 2007-05-08 | Murdoch, David M; Venter, Willem DF; Van Rie, Annelies; Feldman, Charles | AIDS Res Ther | null | null | null | document_parses/pdf_json/e148597ac3bd53fe2dd4fa4fc6677502fc8da423.json | document_parses/pmc_json/PMC1871602.xml.json | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1871602/ | null |
63bos83o | 435baf47b4f78fc06a8376f451993059407d2972 | PMC | Global Surveillance of Emerging Influenza Virus Genotypes by Mass Spectrometry | 10.1371/journal.pone.0000489 | PMC1876795 | 17,534,439 | cc0 | BACKGROUND: Effective influenza surveillance requires new methods capable of rapid and inexpensive genomic analysis of evolving viral species for pandemic preparedness, to understand the evolution of circulating viral species, and for vaccine strain selection. We have developed one such approach based on previously des... | 2007-05-30 | Sampath, Rangarajan; Russell, Kevin L.; Massire, Christian; Eshoo, Mark W.; Harpin, Vanessa; Blyn, Lawrence B.; Melton, Rachael; Ivy, Cristina; Pennella, Thuy; Li, Feng; Levene, Harold; Hall, Thomas A.; Libby, Brian; Fan, Nancy; Walcott, Demetrius J.; Ranken, Raymond; Pear, Michael; Schink, Amy; Gutierrez, Jose; Drader... | PLoS One | null | null | null | document_parses/pdf_json/435baf47b4f78fc06a8376f451993059407d2972.json | document_parses/pmc_json/PMC1876795.xml.json | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1876795/ | null |
hqc7u9w3 | c65f0939cf35a0f04bf93bd6e8f771b8521563a5 | PMC | Transmission Parameters of the 2001 Foot and Mouth Epidemic in Great Britain | 10.1371/journal.pone.0000502 | PMC1876810 | 17,551,582 | cc-by | Despite intensive ongoing research, key aspects of the spatial-temporal evolution of the 2001 foot and mouth disease (FMD) epidemic in Great Britain (GB) remain unexplained. Here we develop a Markov Chain Monte Carlo (MCMC) method for estimating epidemiological parameters of the 2001 outbreak for a range of simple tran... | 2007-06-06 | Chis Ster, Irina; Ferguson, Neil M. | PLoS One | null | null | null | document_parses/pdf_json/c65f0939cf35a0f04bf93bd6e8f771b8521563a5.json | document_parses/pmc_json/PMC1876810.xml.json | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1876810/ | null |
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