Molecule name
stringlengths
12
12
SMILES
stringlengths
31
101
MLM
float64
0
2.38k
ASAP-0015682
O=C(O)C1=CC(Cl)=CC=C1NS(=O)(=O)C1=CC=C(OC2=CC=CC=C2Cl)C=C1
13
ASAP-0015381
COC1=CC=C([C@H](CC2=NN=NN2)NC(=O)C2=NC=NC3=C2C=CN3)C=C1
7
ASAP-0015355
COC1=CC(CC2=C(C)ON=C2C2=CC=C(F)C=C2)=NC(N2CCNCC2)=N1
33
ASAP-0015367
NCC1=CC=CC(NC(=O)[C@@H](NC(=O)OCC2=CC=CC=C2)C2=CC=C(OCC3=CC=CC=C3)C=C2)=C1
1
ASAP-0015169
NC1=NN=C2C=CC(C3=CC=C4NC(=O)CNC4=C3)=CN12
41.8
ASAP-0014994
CNC(=O)C1=CC(Cl)=CC=C1NS(=O)(=O)C1=CC=C(OC2=CC=CC=C2Cl)C=C1
94
ASAP-0014913
CN1C=C(NC(=O)NCC2=CC=CC=N2)C2=CN=CC=C2C1=O
2.08
ASAP-0012944
O=C(/C=C/C1=CC=CC=C1)C(=O)N1CCN(CCC2=CC=CC=C2)CC1
181
ASAP-0014807
CC1=NC=CN1C[C@H](C)CNC(=O)C1=CC=C2COB(O)C2=C1
12
ASAP-0014822
C[C@H]1CN(C[C@H](O)CNC(=O)C2=CC=C3COB(O)C3=C2)CCO1
14
ASAP-0014818
CN1CCN(C)[C@H](CNC(=O)C2=CC=C3COB(O)C3=C2)C1
16
ASAP-0014817
O=C(C1=CC=C2COB(O)C2=C1)N1CCN[C@H](C2=CC=CC=C2)C1
12
ASAP-0014813
O=C(C[C@H]1CCN2C=NC=C2C1)NC1=CC=CC(B(O)O)=C1
6
ASAP-0014761
CC1=CC(NC(=O)NC2=CNC(=O)C3=CC=CC=C23)=NO1
119
ASAP-0014724
CN1CC[C@H](NC(=O)C2=CC=CC(B(O)O)=C2)[C@H]1C1=CC=C(Cl)C=C1
53
ASAP-0014734
CN(C(=O)C1=CC=C2COB(O)C2=C1)[C@H]1CCN(C2CC2)C1
8
ASAP-0014739
O=C(NC1=CC=CC(B(O)O)=C1)[C@H]1CCN2CCC[C@H]2C1
6
ASAP-0014731
O=C(NC1=CC=CC(B(O)O)=C1)[C@H]1CCN(CC2=CC=CC=C2)C1
26
ASAP-0014809
CN(C)C[C@H]1C[C@H](NC(=O)C2=CC=C3COB(O)C3=C2)C1
19
ASAP-0014613
C[C@H]1CN(C2=CN=CC3=CC=CC=C23)C(=O)[C@@]12CN(CC1=CC=NN=C1)C(=O)C1=CC=C(F)C=C12
57
ASAP-0014544
CNC(=O)CN1C[C@@]2(C(=O)N(C3=CN=CC4=CC=CC=C34)C[C@@H]2CNC2=CC=C(Cl)N=N2)C2=CC(Cl)=CC=C2C1=O
75
ASAP-0013892
CNC(=O)CN1C[C@@]2(C(=O)N(C3=CN=CC4=CC=CC=C34)C[C@@H]2CNC2=CN=CS2)C2=CC(Cl)=CC=C2C1=O
77
ASAP-0013898
C[C@H]1CN(C2=CN=CC3=CC=CC=C23)C(=O)[C@@]12CN(CCN1CCN(S(C)(=O)=O)CC1)C(=O)C1=CC=C(Cl)C=C12
237
ASAP-0013925
O=C1C2=CC=C(Cl)C=C2[C@@]2(CN1CCN1CCOCC1)C(=O)N(C1=CN=CC3=CC=CC=C13)C[C@@H]2CNC1=NC=CC=N1
133
ASAP-0013827
CCNC(=O)C1=CC2=C(N[C@H](C3=CC=C4OCCOC4=C3)C(C)C)N=CN=C2N1
72
ASAP-0013814
CNC(=O)CN1C[C@@]2(C(=O)N(C3=CN=CC4=CC=CC=C34)C[C@@H]2CNC2=C(C)N=CS2)C2=CC(Cl)=CC=C2C1=O
33
ASAP-0013824
CCNC(=O)C1=CC2=C(N[C@H](C3=CC=C4OCCOC4=C3)C(C)C)N=CN=C2N1
48
ASAP-0013833
CC(C)[C@H](NC1=NC=NC2=C1C=C(C1=CN(CC(=O)N(C)C)N=C1)N2)C1=CC=C2OCCOC2=C1
35
ASAP-0013837
CC(C)[C@H](NC1=NC=NC2=C1C=C(C1=CN(CC(=O)N(C)C)N=C1)N2)C1=CC=C2OCCOC2=C1
45
ASAP-0013747
CC(C)[C@H](NC1=NC=NC2=C1C=C(C1=CN(CC(=O)N(C)C)N=C1)N2)C1=CC=C2CCCS(=O)(=O)C2=C1
31
ASAP-0013744
CC(C)[C@H](NC1=NC=NC2=C1C=C(C1=CN(CC(=O)N(C)C)N=C1)N2)C1=CC=C2CCCS(=O)(=O)C2=C1
124
ASAP-0013717
CNC(=O)CN1C[C@@]2(C(=O)N(C3=CN=CC4=CC=CC=C34)C[C@@H]2CS(=O)(=O)NC)C2=CC(Cl)=CC=C2C1=O
69
ASAP-0013646
COC1=CC=C(C(=O)NC2=CC=CC(/C=C3/C(=O)NC(=O)C4=CC=CC=C34)=C2)C=C1
127
ASAP-0013722
CC1=NOC(CN2C[C@@]3(C(=O)N(C4=CN=CC5=CC=CC=C45)C[C@@H]3C)C3=CC(F)=CC=C3C2=O)=C1
240
ASAP-0013721
C[C@H]1CN(C2=CN=CC3=CC=CC=C23)C(=O)[C@@]12CN(CC1=NN=NN1C)C(=O)C1=CC=C(F)C=C12
172
ASAP-0013720
C[C@H]1CN(C2=CN=CC3=CC=CC=C23)C(=O)[C@@]12CN(CC1=NC=CN1C)C(=O)C1=CC=C(F)C=C12
351
ASAP-0013719
C[C@H]1CN(C2=CN=CC3=CC=CC=C23)C(=O)[C@@]12CN(CC#N)C(=O)C1=CC=C(F)C=C12
84
ASAP-0013718
CNC(=O)CN1C[C@@]2(C(=O)N(C3=CN=CC4=CC=CC=C34)C[C@@H]2CN2N=CN=N2)C2=CC(Cl)=CC=C2C1=O
46
ASAP-0013716
CNC(=O)CN1C[C@@]2(C(=O)N(C3=CN=CC4=CC=CC=C34)C[C@@H]2CNC2=CN=C(C)S2)C2=CC(Cl)=CC=C2C1=O
90
ASAP-0013398
CCN1N=CC=C1CN1C[C@@]2(C(=O)N(C3=CN=CC4=CC=CC=C34)C[C@@H]2C)C2=CC(F)=CC=C2C1=O
441
ASAP-0013413
C[C@H]1CN(C2=CN=CC3=CC=CC=C23)C(=O)[C@@]12CN(CC1=CC=NN1C)C(=O)C1=CC=C(F)C=C12
353
ASAP-0013412
C[C@H]1CN(C2=CN=CC3=CC=CC=C23)C(=O)[C@@]12CN(CC1=CNN=N1)C(=O)C1=CC=C(F)C=C12
61
ASAP-0013405
CNC(=O)CN1C[C@@]2(C(=O)N(C3=CN=CC4=CC=CC=C34)C[C@@H]2CN2C=CC=N2)C2=CC(Cl)=CC=C2C1=O
83
ASAP-0013407
CNCCN1C[C@@]2(C(=O)N(C3=CN=CC4=CC=CC=C34)C[C@@H]2C)C2=CC(F)=CC=C2C1=O
2
ASAP-0013414
C[C@H]1CN(C2=CN=CC3=CC=CC=C23)C(=O)[C@@]12CN(CC1=COC=N1)C(=O)C1=CC=C(F)C=C12
278
ASAP-0013423
CC1=CN=C(CN2C[C@@]3(C(=O)N(C4=CN=CC5=CC=CC=C45)C[C@@H]3C)C3=CC(F)=CC=C3C2=O)C=N1
237
ASAP-0013303
CNC(=O)CN1C[C@@]2(C(=O)N(C3=CN=CC4=CC=CC=C34)C[C@@H]2CS(=O)(=O)NC)C2=CC(F)=CC=C2C1=O
29
ASAP-0013302
CNC(=O)CN1C[C@@]2(C(=O)N(C3=CN=CC4=CC=CC=C34)C[C@@H]2CS(=O)(=O)N(C)C)C2=CC(Cl)=CC=C2C1=O
123
ASAP-0013311
CN1N=NC(CN2C[C@]3(CCN(C4=CN=CC5=CC=CC=C45)C3=O)C3=CC(Cl)=CC=C3C2=O)=N1
97
ASAP-0013308
CN1C=NC(CN2C[C@]3(CCN(C4=CN=CC5=CC=CC=C45)C3=O)C3=CC(Cl)=CC=C3C2=O)=N1
51
ASAP-0013306
CN1C=CC(CN2C[C@]3(CCN(C4=CN=CC5=CC=CC=C45)C3=O)C3=CC(Cl)=CC=C3C2=O)=N1
308
ASAP-0013313
CN1N=NN=C1CN1C[C@]2(CCN(C3=CN=CC4=CC=CC=C34)C2=O)C2=CC(Cl)=CC=C2C1=O
582
ASAP-0013310
CN1N=NC(CN2C[C@]3(CCN(C4=CN=CC5=CC=CC=C45)C3=O)C3=CC(Cl)=CC=C3C2=O)=N1
227
ASAP-0013309
CN1C=NC(CN2C[C@]3(CCN(C4=CN=CC5=CC=CC=C45)C3=O)C3=CC(Cl)=CC=C3C2=O)=N1
73
ASAP-0013307
CN1C=CC(CN2C[C@]3(CCN(C4=CN=CC5=CC=CC=C45)C3=O)C3=CC(Cl)=CC=C3C2=O)=N1
258
ASAP-0013305
C[C@H]1CN(C2=CN=CC3=CC=CC=C23)C(=O)[C@@]12CN(CC1=NNC=N1)C(=O)C1=CC=C(F)C=C12
19
ASAP-0013304
C[C@H]1CN(C2=CN=CC3=CC=CC=C23)C(=O)[C@@]12CN(CC1=CC(O)=NC=N1)C(=O)C1=CC=C(F)C=C12
11
ASAP-0013300
CNC(=O)CN1C[C@@]2(C(=O)N(C3=CN=CC4=CC=CC=C34)C[C@@H]2CNC2=CC=NC=N2)C2=CC(Cl)=CC=C2C1=O
54
ASAP-0013301
CNC(=O)CN1C[C@@]2(C(=O)N(C3=CN=CC4=CC=CC=C34)C[C@@H]2CNC2=CN=CC=N2)C2=CC(Cl)=CC=C2C1=O
100
ASAP-0013312
CN1N=NN=C1CN1C[C@]2(CCN(C3=CN=CC4=CC=CC=C34)C2=O)C2=CC(Cl)=CC=C2C1=O
129
ASAP-0013256
CC(C)[C@H](NC1=NC=NC2=C1C=C(C1=C(C#N)N(C)N=C1)N2)C1=CC=C2OCC(=O)NC2=C1
147
ASAP-0013274
C[C@H]1CN(C2=CN=CC3=CC=CC=C23)C(=O)[C@@]12CN(CC1=NC=CN1)C(=O)C1=CC=C(F)C=C12
316
ASAP-0013273
C[C@H]1CN(C2=CN=CC3=CC=CC=C23)C(=O)[C@@]12CN(CC1=CC=NN1)C(=O)C1=CC=C(F)C=C12
163
ASAP-0013249
C=CC(=O)N1CCCC2=C1C=CC=C2N(CC1=CC=CC(Cl)=C1)C(=O)CC1=CN=CC2=CC=CC=C12
1,460
ASAP-0013265
CNC(=O)CN1C[C@@]2(C(=O)N(C3=CN=CC4=CC=CC=C34)C[C@@H]2CNC2=CC=CC=C2)C2=CC(Cl)=CC=C2C1=O
495
ASAP-0013266
CNC(=O)CN1C[C@@]2(C(=O)N(C3=CN=CC4=CC=CC=C34)C[C@@H]2CNC2=CN(C)N=C2)C2=CC(Cl)=CC=C2C1=O
90
ASAP-0013268
CNC(=O)CN1C[C@@]2(C(=O)N(C3=CN=CC4=CC=CC=C34)C[C@@H]2CC2=NNN=N2)C2=CC(Cl)=CC=C2C1=O
7
ASAP-0013272
C[C@H]1CN(C2=CN=CC3=CC=CC=C23)C(=O)[C@@]12CN(CC1=CNC=N1)C(=O)C1=CC=C(F)C=C12
91
ASAP-0013255
CC(C)[C@H](NC1=NC=NC2=C1C=C(C1=C(C#N)N(C)N=C1)N2)C1=CC=C2OCC(=O)NC2=C1
81
ASAP-0012329
CC(C)[C@H](NC1=NC=NC2=C1C=C(C1=CN(C)N=C1)N2)C1=CC=C2CCCS(=O)(=O)C2=C1
140
ASAP-0012327
CC(C)[C@H](NC1=NC=NC2=C1C=C(C1=CN(C)N=C1)N2)C1=CC=C2CCCS(=O)(=O)C2=C1
255
ASAP-0012330
CC(C)(C)[C@H](NC1=NC=NC2=C1C=C(C1=CN(CC(N)=O)N=C1)N2)C1=CC=C2OCCOC2=C1
44
ASAP-0012325
CCNC(=O)C1=CC2=C(N[C@H](C3=CC=C4CCCS(=O)(=O)C4=C3)C(C)C)N=CN=C2N1
64
ASAP-0012317
CCNC(=O)C1=CC2=C(N[C@H](C3=CC=C4OCCS(=O)(=O)C4=C3)C(C)C)N=CN=C2N1
26
ASAP-0012320
CC(C)[C@H](NC1=NC=NC2=C1C=C(C1=CN=CC(S(C)(=O)=O)=C1)N2)C1=CC=C2CCCS(=O)(=O)C2=C1
272
ASAP-0012318
CC(C)[C@H](NC1=NC=NC2=C1C=CN2)C1=CC=C2OCCS(=O)(=O)C2=C1
69
ASAP-0012334
CC(C)[C@H](NC1=NC=NC2=C1C=C(C(=O)N[C@H]1CCN(C)C1)N2)C1=CC=C2CCCS(=O)(=O)C2=C1
1
ASAP-0012332
CC(C)(C)[C@H](NC1=NC=NC2=C1C=C(C1=CN(CC(N)=O)N=C1)N2)C1=CC=C2OCCOC2=C1
39
ASAP-0012337
CNCCN1C[C@@]2(C(=O)N(C3=CN=CC4=CC=CC=C34)C[C@@H]2C)C2=CC(Cl)=CC=C2C1=O
3
ASAP-0012336
CC(C)[C@H](NC1=NC=NC2=C1C=C(C(=O)N[C@H]1CCN(C)C1)N2)C1=CC=C2CCCS(=O)(=O)C2=C1
4
ASAP-0012338
CNC(=O)C1=CC=CC(C2=CC3=C(N[C@H](C4=CC=C5CCCS(=O)(=O)C5=C4)C(C)C)N=CN=C3N2)=C1
197
ASAP-0012340
CNC(=O)C1=CC2=C(N[C@H](C3=CC=C4CCCS(=O)(=O)C4=C3)C(C)C)N=CN=C2N1
47
ASAP-0012344
CNC(=O)C1=CC=CC(C2=CC3=C(N[C@H](C4=CC=C5CCCS(=O)(=O)C5=C4)C(C)C)N=CN=C3N2)=C1
882
ASAP-0012346
CNC(=O)C1=CC2=C(N[C@H](C3=CC=C4CCCS(=O)(=O)C4=C3)C(C)C)N=CN=C2N1
23
ASAP-0012339
CO[C@@H](C)CN1C[C@@]2(C(=O)N(C3=CN=CC4=CC=CC=C34)C[C@@H]2C)C2=CC(F)=CC=C2C1=O
371
ASAP-0012331
CO[C@@H](C)CN1C[C@@]2(C(=O)N(C3=CN=CC4=CC=CC=C34)C[C@@H]2C)C2=CC(Cl)=CC=C2C1=O
726
ASAP-0012333
CNC(=O)[C@@H](C)N1C[C@@]2(C(=O)N(C3=CN=CC4=CC=CC=C34)C[C@@H]2C)C2=CC(Cl)=CC=C2C1=O
127
ASAP-0012307
CC(C)[C@H](NC1=NC=NC2=C1C=C(C1=CN(CC(N)=O)N=C1)N2)C1=CC=C2OCCOC2=N1
5
ASAP-0012315
CC(C)[C@H](NC1=NC=NC2=C1C=C(C1=CN(CC(N)=O)N=C1)N2)C1=CC=C2OCCOC2=N1
9
ASAP-0012349
CCNC(=O)C1=CC2=C(N[C@H](C3=CC=C4CCCS(=O)(=O)C4=C3)C(C)C)N=CN=C2N1
54
ASAP-0011513
C[C@H]1CN(C2=CN=CC3=CC=CC=C23)C(=O)[C@@]12CN(CCN1CCOCC1)C(=O)C1=CC=C(Cl)C=C12
368
ASAP-0011428
CC(C)[C@H](NC1=NC=NC2=C1C=C(C1=CN(CC(N)=O)N=C1)N2)C1=CC=C2CCCS(=O)(=O)C2=C1
39
ASAP-0011448
CC1=NN(C)C=C1C1=CC2=C(N[C@H](C3=CC=C4CCCS(=O)(=O)C4=C3)C(C)C)N=CN=C2N1
390
ASAP-0011446
CC1=NN(C)C=C1C1=CC2=C(N[C@H](C3=CC=C4CCCS(=O)(=O)C4=C3)C(C)C)N=CN=C2N1
202
ASAP-0011432
CC(C)[C@H](NC1=NC=NC2=C1C=C(C1=CN(CC(N)=O)N=C1)N2)C1=CC=C2CCCS(=O)(=O)C2=C1
96
ASAP-0011528
CNC(=O)[C@@H](C)N1C[C@@]2(C(=O)N(C3=CN=CC4=CC=CC=C34)C[C@@H]2C)C2=CC(F)=CC=C2C1=O
60
ASAP-0011430
CNC(=O)CN1C[C@@]2(C(=O)N(C3=CN=CC4=CC=CC=C34)C[C@@H]2CC#N)C2=CC(Cl)=CC=C2C1=O
46
ASAP-0011445
C[C@H]1CN(C2=CN=CC3=CC=CC=C23)C(=O)[C@@]12CN(CCN1CCOCC1)C(=O)C1=CC=C(F)C=C12
165
ASAP-0011485
C[C@H]1CN(C2=CN=CC3=CC=CC=C23)C(=O)[C@@]12CN(CC1=CNN=C1)C(=O)C1=CC=C(F)C=C12
672
ASAP-0011359
CNC(=O)C1(N2C[C@@]3(C(=O)N(C4=CN=CC5=CC=CC=C45)C[C@@H]3C)C3=CC(F)=CC=C3C2=O)CC1
43