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A 26-year-old obese woman with a history of bipolar disorder complains that her recent struggles with her weight and eating have caused her to feel depressed. She states that she has recently had difficulty sleeping and feels excessively anxious and agitated. She also states that she has had thoughts of suicide. She of...
eligible ages (years): 18.0-39.0, Bipolar Disorder No clinically significant abnormal findings on the physical examination, medical history, or clinical laboratory results during screening Positive test for HIV, Hepatitis B, or Hepatitis C Treatment with known enzyme altering drugs History of allergic or adverse resp...
1
A 26-year-old obese woman with a history of bipolar disorder complains that her recent struggles with her weight and eating have caused her to feel depressed. She states that she has recently had difficulty sleeping and feels excessively anxious and agitated. She also states that she has had thoughts of suicide. She of...
eligible ages (years): 25.0-45.0, Bipolar Disorder No clinically significant abnormal findings on the physical examination, medical history, or clinical laboratory results during screening Participation in a clinicl trial within 30 days prior to study initiation Positive test for HIV, Hepatitis B, or Hepatitis C Trea...
0
A 26-year-old obese woman with a history of bipolar disorder complains that her recent struggles with her weight and eating have caused her to feel depressed. She states that she has recently had difficulty sleeping and feels excessively anxious and agitated. She also states that she has had thoughts of suicide. She of...
eligible ages (years): 18.0-38.0, Bipolar Disorder No clinically significant abnormal findings on the physical examination, medical history, or clinical laboratory results during screening Positive test for HIV, Hepatitis B, or Hepatitis C Treatment with known enzyme altering drugs History of allergic or adverse resp...
0
A 26-year-old obese woman with a history of bipolar disorder complains that her recent struggles with her weight and eating have caused her to feel depressed. She states that she has recently had difficulty sleeping and feels excessively anxious and agitated. She also states that she has had thoughts of suicide. She of...
eligible ages (years): 18.0-999.0, Bipolar Disorder Depression Meets DSM-IV for Axis I bipolar II disorder Meets DSM-IV for Axis I major depressive episode Score of 16 on 17-item HAM-D rating scale Not taking monoamine oxidase inhibitors (MAOI) for more than 2 weeks prior to study entry Willing to use an effective for...
0
A 26-year-old obese woman with a history of bipolar disorder complains that her recent struggles with her weight and eating have caused her to feel depressed. She states that she has recently had difficulty sleeping and feels excessively anxious and agitated. She also states that she has had thoughts of suicide. She of...
eligible ages (years): 18.0-35.0, Weight Gain Age 18-35 Body mass index between 23 and 30 Interested in preventing weight gain BMI outside of range specified Age outside of range specified History of or current eating disorder or substance abuse Recent weight loss greater than 5% of weight Currently in another resear...
0
A 26-year-old obese woman with a history of bipolar disorder complains that her recent struggles with her weight and eating have caused her to feel depressed. She states that she has recently had difficulty sleeping and feels excessively anxious and agitated. She also states that she has had thoughts of suicide. She of...
eligible ages (years): 12.0-35.0, Depression, Bipolar Depressed bipolar patients (N=100; 15-20 patients/year) Patients will meet DSM-IV for type I bipolar disorder, depressed, as determined by structured interview and best-estimate diagnostic procedures.138 Patient has experienced a maximum of three documented affecti...
1
A 26-year-old obese woman with a history of bipolar disorder complains that her recent struggles with her weight and eating have caused her to feel depressed. She states that she has recently had difficulty sleeping and feels excessively anxious and agitated. She also states that she has had thoughts of suicide. She of...
eligible ages (years): 18.0-64.0, Sleep Initiation and Maintenance Disorders Diagnosis of primary insomnia based on Diagnostic and Statistical Manual of Mental Disorders (DSM-IV)
1
A 26-year-old obese woman with a history of bipolar disorder complains that her recent struggles with her weight and eating have caused her to feel depressed. She states that she has recently had difficulty sleeping and feels excessively anxious and agitated. She also states that she has had thoughts of suicide. She of...
eligible ages (years): 18.0-65.0, Depression DSM-IV diagnosis of major depressive disorder (MDD) Drug naive from prior psychotropic medication for more than 6 months before study entry Hamilton-Depression (HAM-D) 17 score greater than or equal to 16 Woman of childbearing age with a negative pregnancy test within 48 ho...
0
A 26-year-old obese woman with a history of bipolar disorder complains that her recent struggles with her weight and eating have caused her to feel depressed. She states that she has recently had difficulty sleeping and feels excessively anxious and agitated. She also states that she has had thoughts of suicide. She of...
eligible ages (years): 18.0-999.0, Healthy Therapeutic Equivalency Sex: Male or Female; similar proportions of each preferred Age: At least 18 years Weight: must be 15% of ideal weight for height and frame Subjects must be in good health and physical condition as determined by medical history Subjects must read and si...
0
A 26-year-old obese woman with a history of bipolar disorder complains that her recent struggles with her weight and eating have caused her to feel depressed. She states that she has recently had difficulty sleeping and feels excessively anxious and agitated. She also states that she has had thoughts of suicide. She of...
eligible ages (years): 21.0-55.0, Primary Insomnia Patients with insomnia will meet RDC for psychophysiologic insomnia(99). These are provided in Appendix 2. In addition, the complaint of disturbed sleep will have one or more of the following characteristics > 30 minutes to fall asleep (Initial Insomnia) awakenings pe...
0
A 26-year-old obese woman with a history of bipolar disorder complains that her recent struggles with her weight and eating have caused her to feel depressed. She states that she has recently had difficulty sleeping and feels excessively anxious and agitated. She also states that she has had thoughts of suicide. She of...
eligible ages (years): 18.0-999.0, Bipolar Disorder Mania Key Clinical diagnosis of bipolar I disorder mania, manic or mixed episode, with or without psychotic features Current ongoing lithium or valproate treatment with the possibility of benefiting, based on the investigator's clinical judgment, from adjunctive trea...
1
A 26-year-old obese woman with a history of bipolar disorder complains that her recent struggles with her weight and eating have caused her to feel depressed. She states that she has recently had difficulty sleeping and feels excessively anxious and agitated. She also states that she has had thoughts of suicide. She of...
eligible ages (years): 18.0-60.0, Acute Mania in Bipolar Disorder Provision of written informed consent before initiation of any study related procedures. Patients who are deemed incapable of providing informed consent maybe enrolled if written informed consent has been obtained from the patient's Legally Authorized R...
2
A 26-year-old obese woman with a history of bipolar disorder complains that her recent struggles with her weight and eating have caused her to feel depressed. She states that she has recently had difficulty sleeping and feels excessively anxious and agitated. She also states that she has had thoughts of suicide. She of...
eligible ages (years): 18.0-999.0, Healthy Sex: Male or Female; similar proportions of each preferred Age: At least 18 years Weight: must be 15% of ideal weight for height and frame Subjects must be in good health and physical condition as determined by medical history Subjects must read and sign the Consent Form His...
0
A 26-year-old obese woman with a history of bipolar disorder complains that her recent struggles with her weight and eating have caused her to feel depressed. She states that she has recently had difficulty sleeping and feels excessively anxious and agitated. She also states that she has had thoughts of suicide. She of...
eligible ages (years): 12.0-39.0, Schizophrenia Schizoaffective Disorder Schizophreniform; Bipolar I Disorder Bipolar II Bipolar NOS Psychotic Disorder Not Otherwise Specified Autism Children and adolescents ages 12-18 with a diagnosis of Schizophrenia, Schizoaffective Disorder, Schizophreniform, Bipolar I, Bipolar II...
0
A 26-year-old obese woman with a history of bipolar disorder complains that her recent struggles with her weight and eating have caused her to feel depressed. She states that she has recently had difficulty sleeping and feels excessively anxious and agitated. She also states that she has had thoughts of suicide. She of...
eligible ages (years): 18.0-55.0, Methodology Study Age 18-55 BMI 18-30 kg/m2 body weight > 50 kg no history of sleep disorder no concurrent medications no alcohol use no medical issues no smoking
0
A 26-year-old obese woman with a history of bipolar disorder complains that her recent struggles with her weight and eating have caused her to feel depressed. She states that she has recently had difficulty sleeping and feels excessively anxious and agitated. She also states that she has had thoughts of suicide. She of...
eligible ages (years): 18.0-45.0, Bipolar Disorder Medically healthy Meets DSM-IV for bipolar disorder of any subtype No more than 32 weeks gestation, dated by last menstrual period Active suicidality or homicidality Acute psychotic symptoms
0
A 26-year-old obese woman with a history of bipolar disorder complains that her recent struggles with her weight and eating have caused her to feel depressed. She states that she has recently had difficulty sleeping and feels excessively anxious and agitated. She also states that she has had thoughts of suicide. She of...
eligible ages (years): 18.0-65.0, Bipolar I Disorder Male and female adult patients with bipolar 1 disorder and acute agitation Agitation caused primarily by acute intoxication History of drug or alcohol dependence Treatment with benzodiazepines or other hypnotics within 4 hours prior to study drug administration
1
A 26-year-old obese woman with a history of bipolar disorder complains that her recent struggles with her weight and eating have caused her to feel depressed. She states that she has recently had difficulty sleeping and feels excessively anxious and agitated. She also states that she has had thoughts of suicide. She of...
eligible ages (years): 18.0-65.0, Bipolar Disorder Age 18-65 male or female DSM -IV for bipolar I affective disorder Ability and willingness to sign informed consent for participation in the study Unwillingness or inability to participate in the study
2
A 26-year-old obese woman with a history of bipolar disorder complains that her recent struggles with her weight and eating have caused her to feel depressed. She states that she has recently had difficulty sleeping and feels excessively anxious and agitated. She also states that she has had thoughts of suicide. She of...
eligible ages (years): 18.0-60.0, Spinal Cord Injury Subjects of either gender and 18-60 years of age Subjects with chromic spinal cord injury (defined as a history of spinal cord injury for 12 months or longer) Subjects with ASIA classification of A, B, or C for at least 6 months unchanged Spinal cord injury vertebra...
0
A 26-year-old obese woman with a history of bipolar disorder complains that her recent struggles with her weight and eating have caused her to feel depressed. She states that she has recently had difficulty sleeping and feels excessively anxious and agitated. She also states that she has had thoughts of suicide. She of...
eligible ages (years): 18.0-35.0, Healthy Healthy Males age 18 to 35 inclusive Body Mass Index 18 to 30 Willing to adhere to prohibitions and restrictions specified in protocol Must give informed consent Clinically significant abnormal lab values for chemistry, hematology or urinalysis at screening Clinically signifi...
0
A 26-year-old obese woman with a history of bipolar disorder complains that her recent struggles with her weight and eating have caused her to feel depressed. She states that she has recently had difficulty sleeping and feels excessively anxious and agitated. She also states that she has had thoughts of suicide. She of...
eligible ages (years): 8.0-19.0, Psychotic Disorders DSM diagnoses that have an FDA indication for atypical antipsychotic use for at least one agent in the respective pediatric or adult age group. Specifically, primary DSM-IV diagnosis of Early Onset Schizophrenia Spectrum (EOSS; schizophrenia, schizoaffective disorde...
0
A 26-year-old obese woman with a history of bipolar disorder complains that her recent struggles with her weight and eating have caused her to feel depressed. She states that she has recently had difficulty sleeping and feels excessively anxious and agitated. She also states that she has had thoughts of suicide. She of...
eligible ages (years): 60.0-999.0, Dementia Alzheimer Disease Dementia, Vascular Sleep Disorders Circadian Dysregulation Age between 60-99 years Clinical diagnosis of Dementia of the Alzheimer's type or Vascular Dementia Subjects who are too agitated to be able to wear the activity monitors Subjects who are actively ...
0
A 26-year-old obese woman with a history of bipolar disorder complains that her recent struggles with her weight and eating have caused her to feel depressed. She states that she has recently had difficulty sleeping and feels excessively anxious and agitated. She also states that she has had thoughts of suicide. She of...
eligible ages (years): 21.0-55.0, Generalized Anxiety Disease Healthy males and/or females Age from 21 to 55 (inclusive) BMI ranges from 18 to 30 kg/m2 Previous participation in a PD 332334 study Pregnant or nursing females Hypersensitivity (allergic) to lithium, Neurontin (gabapentin), or Lyrica (pregabalin)
0
A 26-year-old obese woman with a history of bipolar disorder complains that her recent struggles with her weight and eating have caused her to feel depressed. She states that she has recently had difficulty sleeping and feels excessively anxious and agitated. She also states that she has had thoughts of suicide. She of...
eligible ages (years): 18.0-65.0, Acute Schizophrenia Provision of written informed consent by both patient and legal representative A diagnosis of schizophrenia by Chinese Classification and Diagnostic of Mental Disorder, 3rd version (CCMD-3) Male or female, aged 18 to 65 years MOAS total score ³ 10 at both screening...
0
A 26-year-old obese woman with a history of bipolar disorder complains that her recent struggles with her weight and eating have caused her to feel depressed. She states that she has recently had difficulty sleeping and feels excessively anxious and agitated. She also states that she has had thoughts of suicide. She of...
eligible ages (years): 18.0-55.0, Weight Gain Subjects must be between the ages of 18 and 55 years old Subjects must have bipolar I disorder, schizophrenia, schizoaffective disorder or MDD as defined by DSM-IV-TR and diagnosed using the Structured Clinical Interview for DSM-IV (SCID) Subjects must have a Young Mania R...
0
A 26-year-old obese woman with a history of bipolar disorder complains that her recent struggles with her weight and eating have caused her to feel depressed. She states that she has recently had difficulty sleeping and feels excessively anxious and agitated. She also states that she has had thoughts of suicide. She of...
eligible ages (years): 18.0-65.0, Bipolar Disorders Metabolic Complication patients with bipolar disorders (I, II, NOS) diagnosed with DSM-IV age between 18 and 65 Decisional capacity is adequate to provide informed consent or has an authorized appropriate surrogate decision maker. in a syndromal remission state at le...
2
A 26-year-old obese woman with a history of bipolar disorder complains that her recent struggles with her weight and eating have caused her to feel depressed. She states that she has recently had difficulty sleeping and feels excessively anxious and agitated. She also states that she has had thoughts of suicide. She of...
eligible ages (years): 18.0-65.0, Acute Bipolar Depression Outpatients that meet the diagnostic for bipolar disorder I and bipolar disorder II with the most recent episode depressed The total score of the scale that's used for the evaluation of depression (HAM-D) should be ≥20 The total score of the scale that' used f...
1
A 26-year-old obese woman with a history of bipolar disorder complains that her recent struggles with her weight and eating have caused her to feel depressed. She states that she has recently had difficulty sleeping and feels excessively anxious and agitated. She also states that she has had thoughts of suicide. She of...
eligible ages (years): 18.0-55.0, Bipolar Disorder Schizophrenia Concurrently taking Zyprexa® for a psychiatric indication such as bipolar disorder or schizophrenia Stable body weight (+ 5%) for at least 2 weeks prior to baseline visit No weight loss program participation within past 3 months Treatment with an atypic...
0
A 26-year-old obese woman with a history of bipolar disorder complains that her recent struggles with her weight and eating have caused her to feel depressed. She states that she has recently had difficulty sleeping and feels excessively anxious and agitated. She also states that she has had thoughts of suicide. She of...
eligible ages (years): 18.0-999.0, Sleep Endometrial Neoplasms Pain be women at least 18 years old have clinical indications of primary endometrioid adenocarcinoma of the endometrium be scheduled for staging surgery by laparotomy under standardized protocols have the ability to communicate in English sufficient for co...
0
A 26-year-old obese woman with a history of bipolar disorder complains that her recent struggles with her weight and eating have caused her to feel depressed. She states that she has recently had difficulty sleeping and feels excessively anxious and agitated. She also states that she has had thoughts of suicide. She of...
eligible ages (years): 18.0-64.0, Sleep Initiation and Maintenance Disorders Primary Insomnia Diagnosis of primary insomnia based on DSM-IV (307.42) Written informed consent has been obtained Patients with sleep apnea syndrome, narcolepsy, presence or suspicion of periodic leg movement or restless leg syndrome Patien...
1
A 26-year-old obese woman with a history of bipolar disorder complains that her recent struggles with her weight and eating have caused her to feel depressed. She states that she has recently had difficulty sleeping and feels excessively anxious and agitated. She also states that she has had thoughts of suicide. She of...
eligible ages (years): 18.0-76.0, Cancer Age: 18-76 Current or historical diagnosis of cancer Projected life expectancy of at least one year DSM-IV diagnoses: Acute Stress Disorder, Generalized Anxiety Disorder, Anxiety Disorder due to cancer, Adjustment Disorder with anxious features Any stage of cancer diagnosis Ep...
0
A 26-year-old obese woman with a history of bipolar disorder complains that her recent struggles with her weight and eating have caused her to feel depressed. She states that she has recently had difficulty sleeping and feels excessively anxious and agitated. She also states that she has had thoughts of suicide. She of...
eligible ages (years): 18.0-60.0, Bipolar Disorder Patients meeting DSM-IV for either Bipolar I, Bipolar II, Cyclothymic Disorder, or Bipolar Disorder NOS Patients on monotherapy treatment with lithium carbonate at steady state level for a minimum of two weeks prior to study treatment assignment Women are postmenopaus...
2
A 26-year-old obese woman with a history of bipolar disorder complains that her recent struggles with her weight and eating have caused her to feel depressed. She states that she has recently had difficulty sleeping and feels excessively anxious and agitated. She also states that she has had thoughts of suicide. She of...
eligible ages (years): 18.0-999.0, Bipolar Disorder Dyssomnias Bipolar disorder patients with sleep disturbance Meeting Diagnostic and Statistical Manual of Mental Disorders, 4th Text Revision (DSM-IV-TR; APA, 2000) diagnostic for bipolar disorder type 1 (established with the SCID: Structured Clinical Interview for DS...
2
A 26-year-old obese woman with a history of bipolar disorder complains that her recent struggles with her weight and eating have caused her to feel depressed. She states that she has recently had difficulty sleeping and feels excessively anxious and agitated. She also states that she has had thoughts of suicide. She of...
eligible ages (years): 18.0-80.0, Multiple System Atrophy Clinical diagnosis of probable MSA (Gilman, et al. 2008) Age ≥18, <80 Heart failure Liver disease Kidney failure Thyroid disease Sick sinus syndrome and/or significant ECG alterations Hyposodemia Treatment with diuretics Treatment with haloperidol and/or other...
0
A 26-year-old obese woman with a history of bipolar disorder complains that her recent struggles with her weight and eating have caused her to feel depressed. She states that she has recently had difficulty sleeping and feels excessively anxious and agitated. She also states that she has had thoughts of suicide. She of...
eligible ages (years): 18.0-80.0, SPINOCEREBELLAR ATAXIA 2 Molecular diagnosis of SCA2 (≥34 CAG in the ataxin-2 gene) Age ≥18, <80 SARA score ≥8 SARA score >32 Heart failure Liver disease Kidney failure Thyroid disease Sick sinus syndrome and/or significant ECG alterations Hyposodemia Treatment with diuretics Treatme...
0
A 26-year-old obese woman with a history of bipolar disorder complains that her recent struggles with her weight and eating have caused her to feel depressed. She states that she has recently had difficulty sleeping and feels excessively anxious and agitated. She also states that she has had thoughts of suicide. She of...
eligible ages (years): 20.0-65.0, Sleep Initiation and Maintenance Disorders Patient is diagnosed as a primary insomnia according to the Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition (DSM-IV) Patients complaining of insomnia continuously for 4 weeks or longer Patient's usual bedtime is between ...
0
A 26-year-old obese woman with a history of bipolar disorder complains that her recent struggles with her weight and eating have caused her to feel depressed. She states that she has recently had difficulty sleeping and feels excessively anxious and agitated. She also states that she has had thoughts of suicide. She of...
eligible ages (years): 21.0-70.0, Primary Insomnia age 21-70 yrs non-pregnant females who agree to standard birth control for 12 months and males two of the following chronic insomnia complaints: >30 min sleep latency, < 6 hrs sleep, or nonrestorative sleep meet DSM-IV for primary insomnia any acute or unstable illne...
0
A 26-year-old obese woman with a history of bipolar disorder complains that her recent struggles with her weight and eating have caused her to feel depressed. She states that she has recently had difficulty sleeping and feels excessively anxious and agitated. She also states that she has had thoughts of suicide. She of...
eligible ages (years): 18.0-90.0, Bipolar Disorder Have a diagnosis of bipolar disorder Be 18 years or older Be a biological parent of a child who is younger than 30 years old Be willing to participate in the survey The participant must be (or must have been) the primary caretaker for his or her child A participant m...
1
A 26-year-old obese woman with a history of bipolar disorder complains that her recent struggles with her weight and eating have caused her to feel depressed. She states that she has recently had difficulty sleeping and feels excessively anxious and agitated. She also states that she has had thoughts of suicide. She of...
eligible ages (years): 18.0-65.0, Depression The patient has a diagnosis of bipolar I disorder according to Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition (Text Revision) (DSM-IV-TR) and is currently experiencing a major depressive episode Documentation that the patient has had at least 1 previo...
0
A 26-year-old obese woman with a history of bipolar disorder complains that her recent struggles with her weight and eating have caused her to feel depressed. She states that she has recently had difficulty sleeping and feels excessively anxious and agitated. She also states that she has had thoughts of suicide. She of...
eligible ages (years): 18.0-65.0, Schizophrenia Diagnosis of schizophrenia, schizoaffective disorder, or schizophreniform Females who participate in this study are unable to have children-OR- are willing to remain abstinent from Day -5 until 90 days after discharge Males must be willing to remain sexually abstinent or...
0
A 26-year-old obese woman with a history of bipolar disorder complains that her recent struggles with her weight and eating have caused her to feel depressed. She states that she has recently had difficulty sleeping and feels excessively anxious and agitated. She also states that she has had thoughts of suicide. She of...
eligible ages (years): 14.0-45.0, Schizophreniform Disorder Bipolar I Disorder Bipolar II Disorder Major Depressive Disorder With Psychotic Features, Substance-Induced Psychoses Psychosis Not Otherwise Specified Schizophrenia Schizoaffective Disorder Age between 14 and 45 years (inclusive) Male or Female gender DSM-IV...
0
A 26-year-old obese woman with a history of bipolar disorder complains that her recent struggles with her weight and eating have caused her to feel depressed. She states that she has recently had difficulty sleeping and feels excessively anxious and agitated. She also states that she has had thoughts of suicide. She of...
eligible ages (years): 18.0-65.0, Nicotine Dependence Structured Clinical Interview (SCID) derived DSM-IV diagnoses of Bipolar Disorder (Type I or II), and Nicotine Dependence Young Mania Rating Scale Total Score <12 at study entry HAM-D 17-Item Score >5 and <24 at study entry Fagerstrom Test for Nicotine Dependence (...
0
A 26-year-old obese woman with a history of bipolar disorder complains that her recent struggles with her weight and eating have caused her to feel depressed. She states that she has recently had difficulty sleeping and feels excessively anxious and agitated. She also states that she has had thoughts of suicide. She of...
eligible ages (years): 18.0-40.0, Weight Gain non-smoking, adults < 16 weeks gestation medical comorbidities
0
A 26-year-old obese woman with a history of bipolar disorder complains that her recent struggles with her weight and eating have caused her to feel depressed. She states that she has recently had difficulty sleeping and feels excessively anxious and agitated. She also states that she has had thoughts of suicide. She of...
eligible ages (years): 19.0-65.0, Major Depressive Disorder Suicidality 19-65 years of age Diagnosis of major depressive disorder Currently experiencing suicidal thoughts Depressed patients without suicidality Patients with severe psychotic features or with primary diagnoses of bipolar disorder, schizoaffective disor...
0
A 26-year-old obese woman with a history of bipolar disorder complains that her recent struggles with her weight and eating have caused her to feel depressed. She states that she has recently had difficulty sleeping and feels excessively anxious and agitated. She also states that she has had thoughts of suicide. She of...
eligible ages (years): 18.0-50.0, Sleep Memory to 50 years of age no sleep complaints or problems good sleep quality per questionnaire sufficient time in bed each night any clinically significant unstable medical condition recent psychiatric disorder prior diagnosis or symptoms of a sleep disorder recent history of s...
0
A 26-year-old obese woman with a history of bipolar disorder complains that her recent struggles with her weight and eating have caused her to feel depressed. She states that she has recently had difficulty sleeping and feels excessively anxious and agitated. She also states that she has had thoughts of suicide. She of...
eligible ages (years): 7.0-17.0, Bipolar Disorder Participants aged 7 years to 17 years, 11 months old at time of first dose Participants must meet DSM-IV diagnostic as assessed by a semi-structured assessment (KSADS-PL) and a separate clinical interview with a child/adolescent psychiatrist for manic or mixed episodes...
0
A 26-year-old obese woman with a history of bipolar disorder complains that her recent struggles with her weight and eating have caused her to feel depressed. She states that she has recently had difficulty sleeping and feels excessively anxious and agitated. She also states that she has had thoughts of suicide. She of...
eligible ages (years): 18.0-65.0, Bipolar Disorder Panic Disorder Generalized Anxiety Disorder Subjects must at least age of 18 years of age and not older than 65 Subjects must have lifetime bipolar I, II, or NOS disorder as defined by DSM-IV TR (26) Subjects must have lifetime panic disorder or generalized anxiety di...
0
A 26-year-old obese woman with a history of bipolar disorder complains that her recent struggles with her weight and eating have caused her to feel depressed. She states that she has recently had difficulty sleeping and feels excessively anxious and agitated. She also states that she has had thoughts of suicide. She of...
eligible ages (years): 18.0-64.0, Sleep Initiation and Maintenance Disorders Primary Insomnia Diagnosis of primary insomnia based on DSM-IV (307.42) Written informed consent has been obtained Patients with sleep apnea syndrome, narcolepsy, presence or suspicion of periodic leg movement or restless leg syndrome Patien...
1
A 26-year-old obese woman with a history of bipolar disorder complains that her recent struggles with her weight and eating have caused her to feel depressed. She states that she has recently had difficulty sleeping and feels excessively anxious and agitated. She also states that she has had thoughts of suicide. She of...
eligible ages (years): 18.0-999.0, Depression Anxiety Disorders Clinical diagnosis of Major Depressive Disorder or more on MADRS-S Severe depression (more than 35 on MADRS-S or based on interview) Severe psychiatric condition (e.g. psychosis or bipolar disorder) Changed medication during the last three months
0
A 26-year-old obese woman with a history of bipolar disorder complains that her recent struggles with her weight and eating have caused her to feel depressed. She states that she has recently had difficulty sleeping and feels excessively anxious and agitated. She also states that she has had thoughts of suicide. She of...
eligible ages (years): 11.0-17.0, Eating Disorder Male or female between 11 and 17 (less than 18) at beginning of trial Based on the Diagnostic and Statistical Manual of Mental Disorders (DSM-IV), patient fulfills for diagnosis of Anorexia Nervosa (of which there are two types: restricting or binge-eating/purging) or ...
0
A 26-year-old obese woman with a history of bipolar disorder complains that her recent struggles with her weight and eating have caused her to feel depressed. She states that she has recently had difficulty sleeping and feels excessively anxious and agitated. She also states that she has had thoughts of suicide. She of...
eligible ages (years): 30.0-65.0, Multiple Sclerosis Diagnosis of a progressive subtype of multiple sclerosis by revised 2005 McDonald Criteria EDSS of 3.0-6.5 Ages 30-65 Must be mentally capable of providing informed consent and following study guidelines Relapse or steroid treatment within 1 month of trial entry An...
0
A 26-year-old obese woman with a history of bipolar disorder complains that her recent struggles with her weight and eating have caused her to feel depressed. She states that she has recently had difficulty sleeping and feels excessively anxious and agitated. She also states that she has had thoughts of suicide. She of...
eligible ages (years): 18.0-999.0, Medication Adherence Bipolar Disorder Diagnosis of Type I or II BD for at least 6 months (confirmed with MINI) On maintenance evidence-based treatment for BD (lithium, antipsychotic, anticonvulsant) Have weight gain concerns that individual believes are related to BD medication treat...
1
A 26-year-old obese woman with a history of bipolar disorder complains that her recent struggles with her weight and eating have caused her to feel depressed. She states that she has recently had difficulty sleeping and feels excessively anxious and agitated. She also states that she has had thoughts of suicide. She of...
eligible ages (years): 18.0-65.0, Depression With Prominent Agitation Male or female Age 18 to 65 Outpatient at enrolment A diagnosis of major depressive disorder Baseline HAMD-17 score > 20 and HAMD Item1 score > 2 both at enrolment and baseline Significant agitation CGI-S score > 4 at screening and baseline Negative...
0
A 26-year-old obese woman with a history of bipolar disorder complains that her recent struggles with her weight and eating have caused her to feel depressed. She states that she has recently had difficulty sleeping and feels excessively anxious and agitated. She also states that she has had thoughts of suicide. She of...
eligible ages (years): 18.0-40.0, Bipolar Affective Disorders Cyclothymic Disorder Schizoaffective Disorder Major Depressive Disorder Dysthymic Disorder Obsessive-Compulsive Disorder Panic Disorder Posttraumatic Stress Disorder Premenstrual Dysphoric Disorder Social Anxiety Disorder 40 year old female women currently ...
2
A 26-year-old obese woman with a history of bipolar disorder complains that her recent struggles with her weight and eating have caused her to feel depressed. She states that she has recently had difficulty sleeping and feels excessively anxious and agitated. She also states that she has had thoughts of suicide. She of...
eligible ages (years): 18.0-999.0, Fathers Parenting High-risk Child Maltreatment Prevention Male Guardian Child enrolled in partnering Head Start site Mental Health issues that prohibit involvement in group-based prevention study (e.g., psychosis)
0
A 26-year-old obese woman with a history of bipolar disorder complains that her recent struggles with her weight and eating have caused her to feel depressed. She states that she has recently had difficulty sleeping and feels excessively anxious and agitated. She also states that she has had thoughts of suicide. She of...
eligible ages (years): 18.0-999.0, Major Depressive Disorder men or women age of 18 years or older meet for major depressive episode, and have a family history of bipolar disorder or completed suicide subjects not able to give informed consent pregnant or breast-feeding women current panic disorder, post traumatic st...
0
A 26-year-old obese woman with a history of bipolar disorder complains that her recent struggles with her weight and eating have caused her to feel depressed. She states that she has recently had difficulty sleeping and feels excessively anxious and agitated. She also states that she has had thoughts of suicide. She of...
eligible ages (years): 0.0-999.0, Bipolar Disorder Patients with bipolar disorder Patients treated with lamotrigine tablets for the first time
0
A 26-year-old obese woman with a history of bipolar disorder complains that her recent struggles with her weight and eating have caused her to feel depressed. She states that she has recently had difficulty sleeping and feels excessively anxious and agitated. She also states that she has had thoughts of suicide. She of...
eligible ages (years): 18.0-65.0, Spinal Cord Injury either gender and 18-65 years old acute or subacute traumatic spinal cord injury (defined as SCI resulting from an exteneral non-penetrating cause that occurred within 4 weeks) neurological status of ASIA A neurological level between C5-T11 MRI shows injury site is ...
0
A 26-year-old obese woman with a history of bipolar disorder complains that her recent struggles with her weight and eating have caused her to feel depressed. She states that she has recently had difficulty sleeping and feels excessively anxious and agitated. She also states that she has had thoughts of suicide. She of...
eligible ages (years): 18.0-999.0, Schizophrenia Diagnosis (DSM-IV) of schizophrenia or functional psychosis including schizophreniform and acute psychosis with schizophrenia symptoms Receiving olanzapine treatment for no more than 3 months The dose of olanzapine is stable for at least 2 weeks prior to randomisation (...
0
A 26-year-old obese woman with a history of bipolar disorder complains that her recent struggles with her weight and eating have caused her to feel depressed. She states that she has recently had difficulty sleeping and feels excessively anxious and agitated. She also states that she has had thoughts of suicide. She of...
eligible ages (years): 18.0-999.0, Bipolar Disorder Able to provide informed consent before beginning any study-specific procedures Male and female patients at least 18 years of age Meets Diagnostic and Statistical Manual -IV for BPI, BP II, or National Comorbidity Survey-R for sub-threshold BP with or without symptom...
2
A 26-year-old obese woman with a history of bipolar disorder complains that her recent struggles with her weight and eating have caused her to feel depressed. She states that she has recently had difficulty sleeping and feels excessively anxious and agitated. She also states that she has had thoughts of suicide. She of...
eligible ages (years): 60.0-999.0, Sleep Duration on the First Night After Surgery Total hip or knee replacement in fast-track setup Age 60 years or above ASA class 1-3 Anesthesia within the pas 30 days Daily use of alcohol > 21 units / week Use of anxiolytics or hypnotics within the past 30 days Inability to read an...
0
A 26-year-old obese woman with a history of bipolar disorder complains that her recent struggles with her weight and eating have caused her to feel depressed. She states that she has recently had difficulty sleeping and feels excessively anxious and agitated. She also states that she has had thoughts of suicide. She of...
eligible ages (years): 18.0-65.0, Insomnia Depression Suicidal Ideation Persons 18-65 years of age Persons with confirmed DSM-IV diagnosis of MDE by SCID Persons with Research Diagnostic diagnosis of insomnia Persons free of all psychotropic medications for one week before baseline assessment, except that prior FLX tr...
1
A 26-year-old obese woman with a history of bipolar disorder complains that her recent struggles with her weight and eating have caused her to feel depressed. She states that she has recently had difficulty sleeping and feels excessively anxious and agitated. She also states that she has had thoughts of suicide. She of...
eligible ages (years): 18.0-999.0, Bipolar Disorder Insomnia Fulfilling for SCID-1-verified bipolar I or II disorder Euthymic, as defined by Montgomery Åsberg Depression Rating Scale (MADRS) not higher than eleven, and Young Mania Rating scale (YMRS) not higher than five Fulfilling DSM-IV for primary insomnia or insom...
1
A 26-year-old obese woman with a history of bipolar disorder complains that her recent struggles with her weight and eating have caused her to feel depressed. She states that she has recently had difficulty sleeping and feels excessively anxious and agitated. She also states that she has had thoughts of suicide. She of...
eligible ages (years): 0.5-85.0, Influenza For adults and old people Healthy adults aged 18-60 years old, and healthy old people aged >60 years Be able to show legal identity card for the sake of recruitment Without vaccination history of seasonal split influenza vaccine in the recent 3 years Not participate in any ot...
0
A 26-year-old obese woman with a history of bipolar disorder complains that her recent struggles with her weight and eating have caused her to feel depressed. She states that she has recently had difficulty sleeping and feels excessively anxious and agitated. She also states that she has had thoughts of suicide. She of...
eligible ages (years): 18.0-65.0, Bipolar Disorder Insomnia Hypersomnia Sleep Problems Men and women age 18-65 DSM-IV diagnosis of bipolar I or II disorder HAM-D-17 score < 17 (i.e. low or no depressive symptoms) YMRS score < 8 (i.e. no or low manic symptoms) Optimized, stable maintenance pharmacotherapy at maximum to...
0
A 26-year-old obese woman with a history of bipolar disorder complains that her recent struggles with her weight and eating have caused her to feel depressed. She states that she has recently had difficulty sleeping and feels excessively anxious and agitated. She also states that she has had thoughts of suicide. She of...
eligible ages (years): 13.0-21.0, Adolescent - Emotional Problem age 13 to 21 experience a moderately elevated level of depressive symptoms on the CES-D scale (score 16-34) may or may not have had a past history of depression, anxiety and/or substance abuse currently diagnosed with depression, schizophrenia, or bipol...
0
A 26-year-old obese woman with a history of bipolar disorder complains that her recent struggles with her weight and eating have caused her to feel depressed. She states that she has recently had difficulty sleeping and feels excessively anxious and agitated. She also states that she has had thoughts of suicide. She of...
eligible ages (years): 18.0-65.0, Bipolar Disorder Age 18-65 written informed consent meets DSM-IV (by SCID-I/P) for bipolar I disorder, current episode depressed MADRS score of at least 20 (i.e., moderate depression) and no greater than 34 (i.e., severe depression) at screen and baseline visit YMRS score < 12 at scre...
2
A 26-year-old obese woman with a history of bipolar disorder complains that her recent struggles with her weight and eating have caused her to feel depressed. She states that she has recently had difficulty sleeping and feels excessively anxious and agitated. She also states that she has had thoughts of suicide. She of...
eligible ages (years): 17.0-40.0, Primary Insomnia Secondary Insomnia primary insomnia secondary insomnia requiring sleep medication (Zolpidem) for a three-week trial active duty military service member stationed at Fort Carson secondary insomnia to a likely medical condition, such as sleep apnea, chronic obstructive...
0
A 26-year-old obese woman with a history of bipolar disorder complains that her recent struggles with her weight and eating have caused her to feel depressed. She states that she has recently had difficulty sleeping and feels excessively anxious and agitated. She also states that she has had thoughts of suicide. She of...
eligible ages (years): 18.0-65.0, Neuropathic Pain Neuralgia Spinal Cord Injuries Age 18 Diagnosis of traumatic spinal cord injury Clinically diagnosed neuropathic pain Pain severity is at least 4 on a 11-point numeric rating scale at screening Pain present regularly for at least 6 weeks before enrollment Able to unde...
0
A 26-year-old obese woman with a history of bipolar disorder complains that her recent struggles with her weight and eating have caused her to feel depressed. She states that she has recently had difficulty sleeping and feels excessively anxious and agitated. She also states that she has had thoughts of suicide. She of...
eligible ages (years): 10.0-25.0, Bipolar Disorder have at least one biological parent diagnosed as bipolar disorder (bipolar I or II) have at least one of the following syndromes i) two or more DSM-IV defined hypomania/mania symptoms, lasting for at least 4 days; ii) two or more DSM defined major depressive symptoms,...
1
A 26-year-old obese woman with a history of bipolar disorder complains that her recent struggles with her weight and eating have caused her to feel depressed. She states that she has recently had difficulty sleeping and feels excessively anxious and agitated. She also states that she has had thoughts of suicide. She of...
eligible ages (years): 18.0-65.0, Bipolar Disorder Anxiety Disorders Men and women age 18-65 DSM-IV diagnosis of bipolar I disorder and at least one of three additional anxiety disorders generalized anxiety disorder, panic disorder, or social phobia HAM-D-17 score <16 (i.e. depressive symptoms) YMRS score < 12 (i.e. n...
0
A 26-year-old obese woman with a history of bipolar disorder complains that her recent struggles with her weight and eating have caused her to feel depressed. She states that she has recently had difficulty sleeping and feels excessively anxious and agitated. She also states that she has had thoughts of suicide. She of...
eligible ages (years): 18.0-65.0, Bipolar Disorder with a diagnosis of bipolar I disorder, manic or mixed phase equal or more than 18 scores in Young Mania Rating Scale (YMRS) Serious general medical illness pregnancy and lactation given long-acting antipsychotic drug within the last two month endocrine disease( e.g....
2
A 26-year-old obese woman with a history of bipolar disorder complains that her recent struggles with her weight and eating have caused her to feel depressed. She states that she has recently had difficulty sleeping and feels excessively anxious and agitated. She also states that she has had thoughts of suicide. She of...
eligible ages (years): 20.0-64.0, Primary Insomnia Men or women aged between 20 and 64 years Diagnosis of primary insomnia according to defined by DSM-IV Difficulty in maintaining sleep and waking up until 3 am Not having used any psychoactive drug in the last 30 days prior to their in the study Signature of IC Previ...
0
A 26-year-old obese woman with a history of bipolar disorder complains that her recent struggles with her weight and eating have caused her to feel depressed. She states that she has recently had difficulty sleeping and feels excessively anxious and agitated. She also states that she has had thoughts of suicide. She of...
eligible ages (years): 0.0-999.0, Depressive Disorder Bipolar Disorder Suicide Suicide, Attempted Must be a Veteran of the United States Armed Forces Survived an episode of suicidal self-directed violence (including suicide attempts and interrupted attempts) that occurred within three months of admission to the study,...
0
A 26-year-old obese woman with a history of bipolar disorder complains that her recent struggles with her weight and eating have caused her to feel depressed. She states that she has recently had difficulty sleeping and feels excessively anxious and agitated. She also states that she has had thoughts of suicide. She of...
eligible ages (years): 18.0-65.0, Bipolar Disorder Major Depressive Episode Suicidal Ideation Bipolar depression with current major depressive episode (MDE). Participants may be psychiatric medication-free, or if on psychiatric medication, not responding adequately given current MDE with suicidal ideation Moderate to ...
2
A 26-year-old obese woman with a history of bipolar disorder complains that her recent struggles with her weight and eating have caused her to feel depressed. She states that she has recently had difficulty sleeping and feels excessively anxious and agitated. She also states that she has had thoughts of suicide. She of...
eligible ages (years): 7.0-17.0, Bipolar Disorder Pediatric Bipolar Disorder Childhood-onset Bipolar Disorder 17 years old bipolar disorder type I preferred (at least 1 week of mania) no implanted metal (no braces, no cochlear implants) can not have full Diagnostic and Statistical Manual 4th Edition (DSM-IV) autistic...
0
A 26-year-old obese woman with a history of bipolar disorder complains that her recent struggles with her weight and eating have caused her to feel depressed. She states that she has recently had difficulty sleeping and feels excessively anxious and agitated. She also states that she has had thoughts of suicide. She of...
eligible ages (years): 12.0-18.0, Dialectical Behavior Therapy + Pharmacotherapy Standard of Care Psychotherapy + Pharmacotherapy For the proposed study, are as follows: 1) age 12 years, 0 months to 18 years, 11 months; 2) a diagnosis of Bipolar Disorder (BP) I, II or NOS by the K-SADS-PL with an acute manic, mixed or...
0
A 26-year-old obese woman with a history of bipolar disorder complains that her recent struggles with her weight and eating have caused her to feel depressed. She states that she has recently had difficulty sleeping and feels excessively anxious and agitated. She also states that she has had thoughts of suicide. She of...
eligible ages (years): 18.0-999.0, Suicide Risk Assessment nurses who work in a variety of wards such as Hematology, Oncology, Stroke and Rehabilitation where potential cases with high suicide risk may be identified
0
A 26-year-old obese woman with a history of bipolar disorder complains that her recent struggles with her weight and eating have caused her to feel depressed. She states that she has recently had difficulty sleeping and feels excessively anxious and agitated. She also states that she has had thoughts of suicide. She of...
eligible ages (years): 18.0-999.0, Suicidal Ideation/Behavior Depression Major depressive episode; inpatient at screening visit; suicidal ideation/behaviour present defined by a clinical rating of 8 on the Sheehan Suicidality Tracking Scale (S-STS) and a rating of ≥20 on the Montgomery Asberg Depression Scale (MADRS) ...
0
A 26-year-old obese woman with a history of bipolar disorder complains that her recent struggles with her weight and eating have caused her to feel depressed. She states that she has recently had difficulty sleeping and feels excessively anxious and agitated. She also states that she has had thoughts of suicide. She of...
eligible ages (years): 10.0-17.0, Childhood Anxiety Parents With Bipolar Disorder Children at Risk for Bipolar Disorder 17 years old At least one parent with bipolar disorder Meets clinical for a specific anxiety disorder PARS -5 item scale score > 10 at screening and baseline of initial study phase Fluent in English ...
0
A 26-year-old obese woman with a history of bipolar disorder complains that her recent struggles with her weight and eating have caused her to feel depressed. She states that she has recently had difficulty sleeping and feels excessively anxious and agitated. She also states that she has had thoughts of suicide. She of...
eligible ages (years): 2.0-9.0, Parental/Caregiver Anxiety Child's Anxiety Pediatric patients ages 2-9 years ASA class I-II inpatient surgeries of at least 2 hours duration requiring postoperative admission of at least 23 hours contraindication to preoperative sedation, known allergy or sensitivity to the study medic...
0
A 26-year-old obese woman with a history of bipolar disorder complains that her recent struggles with her weight and eating have caused her to feel depressed. She states that she has recently had difficulty sleeping and feels excessively anxious and agitated. She also states that she has had thoughts of suicide. She of...
eligible ages (years): 18.0-60.0, Bipolar Disorder The patient was correctly informed about the study The patient must be insured or beneficiary of a health insurance plan The diagnosis of bipolar disorder is confirmed by the doctor referring the patient to the BEC and confirmed during the preliminary interview at the...
0
A 26-year-old obese woman with a history of bipolar disorder complains that her recent struggles with her weight and eating have caused her to feel depressed. She states that she has recently had difficulty sleeping and feels excessively anxious and agitated. She also states that she has had thoughts of suicide. She of...
eligible ages (years): 13.0-21.0, Bipolar Disorder Suicidal Ideation Diagnosis of Bipolar Disorder I, Bipolar Disorder II, or Bipolar Disorder Not Otherwise Specified Living with or in close contact with at least one parent who is willing to participate Have had at least 1 week in the prior 3 months of significant sui...
0
A 26-year-old obese woman with a history of bipolar disorder complains that her recent struggles with her weight and eating have caused her to feel depressed. She states that she has recently had difficulty sleeping and feels excessively anxious and agitated. She also states that she has had thoughts of suicide. She of...
eligible ages (years): 18.0-69.0, Insomnia age between 18 years to 69 years fluent in German language provide written informed consent ability to understand the explanations and instructions given by the study physician and the investigator Sleep disorders caused by medical factors (e.g. sleep apnea, restless legs sy...
0
A 26-year-old obese woman with a history of bipolar disorder complains that her recent struggles with her weight and eating have caused her to feel depressed. She states that she has recently had difficulty sleeping and feels excessively anxious and agitated. She also states that she has had thoughts of suicide. She of...
eligible ages (years): 13.0-19.0, Insomnia Depression Between 13-19 years of age Are depressed Have insomnia Are not depressed Do not have insomnia Currently using a sleep aid Have bipolar depression Have psychotic disorder Have a sleep disorder other than insomnia
0
A 26-year-old obese woman with a history of bipolar disorder complains that her recent struggles with her weight and eating have caused her to feel depressed. She states that she has recently had difficulty sleeping and feels excessively anxious and agitated. She also states that she has had thoughts of suicide. She of...
eligible ages (years): 18.0-999.0, Prostate Cancer Ability to understand and the willingness to sign a written informed consent form Subjects with histologically confirmed local adenocarcinoma of the prostate who have elected to proceed with radical prostatectomy as primary curative therapy Subjects having no prior ad...
0
A 26-year-old obese woman with a history of bipolar disorder complains that her recent struggles with her weight and eating have caused her to feel depressed. She states that she has recently had difficulty sleeping and feels excessively anxious and agitated. She also states that she has had thoughts of suicide. She of...
eligible ages (years): 21.0-65.0, Schizophrenia Metabolic Syndrome Vitamin D Deficiency • Men and women with a DSM-IV clinical diagnosis of Schizophrenia, Schizoaffective or Bipolar disorder to 65 years of age; male and female A willingness and ability to provide signed informed consent The subject should have been on...
0
A 26-year-old obese woman with a history of bipolar disorder complains that her recent struggles with her weight and eating have caused her to feel depressed. She states that she has recently had difficulty sleeping and feels excessively anxious and agitated. She also states that she has had thoughts of suicide. She of...
eligible ages (years): 18.0-65.0, Bipolar Disorder major depressive episode in type2 bipolar disorder or bipolar disorder NOS.(MADRS more than 20 point) ears to 65years subjects who sign the informed consent document don't have Diabetes and abnormal metabolism of sugar not noticed as bipolar disorder have an organic ...
0
A 26-year-old obese woman with a history of bipolar disorder complains that her recent struggles with her weight and eating have caused her to feel depressed. She states that she has recently had difficulty sleeping and feels excessively anxious and agitated. She also states that she has had thoughts of suicide. She of...
eligible ages (years): 18.0-65.0, Bipolar Disorder Suicidal Ideation Depression Meets DSM-IV for BD I and II current depressive episode Able to give written informed consent Age > to 18 years and < 65 years Currently suicidal as defined by a MADRS suicide item score of > 3 or previous history of serious suicidal ideat...
2
A 26-year-old obese woman with a history of bipolar disorder complains that her recent struggles with her weight and eating have caused her to feel depressed. She states that she has recently had difficulty sleeping and feels excessively anxious and agitated. She also states that she has had thoughts of suicide. She of...
eligible ages (years): 21.0-50.0, Healthy Be in good general health as determined by the investigator Have a 3-month history of a normal nightly sleep pattern based on the subject's self report A usual time in bed A regular bedtime between 2200 and 2400 hours No habitual daytime napping Epworth Sleepiness Scale score...
1
A 26-year-old obese woman with a history of bipolar disorder complains that her recent struggles with her weight and eating have caused her to feel depressed. She states that she has recently had difficulty sleeping and feels excessively anxious and agitated. She also states that she has had thoughts of suicide. She of...
eligible ages (years): 18.0-45.0, Diabetes Weight Gain Weight Loss Cardiovascular Disease Obesity Participants will be men of European (self-report of both parents of white European origin) or South Asian (self-report of both parents of Indian, Pakistani, Bangladeshi or Sri Lankan origin) with BMI <25 kg.m-2, who have...
0
A 26-year-old obese woman with a history of bipolar disorder complains that her recent struggles with her weight and eating have caused her to feel depressed. She states that she has recently had difficulty sleeping and feels excessively anxious and agitated. She also states that she has had thoughts of suicide. She of...
eligible ages (years): 18.0-70.0, Cirrhosis Age 18 to 70 years Clinical, Biochemical, Radiological ,Histological evidence of cirrhosis of all etiology Child A and B cirrhosis Cirrhosis patients giving h/o persistent sleep disturbances Active alcohol intake or intake within 1 month of enrollment Active substance abuse...
0
A 26-year-old obese woman with a history of bipolar disorder complains that her recent struggles with her weight and eating have caused her to feel depressed. She states that she has recently had difficulty sleeping and feels excessively anxious and agitated. She also states that she has had thoughts of suicide. She of...
eligible ages (years): 18.0-55.0, Bipolar Disorder Age 18 or older If Pregnant, equal to or less than 26 weeks English-speaking DSM-IV Bipolar Disorder, any subtype, Major Depressive Disorder, or Mood Disorder Not Otherwise Specified Able to provide informed consent Daily dosing of lithium Active substance abuse with...
0
A 26-year-old obese woman with a history of bipolar disorder complains that her recent struggles with her weight and eating have caused her to feel depressed. She states that she has recently had difficulty sleeping and feels excessively anxious and agitated. She also states that she has had thoughts of suicide. She of...
eligible ages (years): 18.0-999.0, Anxiety Depression Bipolar I Disorder Bipolar II Disorder Age 18 or older Experiencing mood disorders (e.g. depression, anxiety, bipolar) defined as a visit with a specified DSM-V code (295.7 Schizoaffective Disorder (Depressive type), 295.7 Schizoaffective Disorder (Bipolar type), 2...
2
A 26-year-old obese woman with a history of bipolar disorder complains that her recent struggles with her weight and eating have caused her to feel depressed. She states that she has recently had difficulty sleeping and feels excessively anxious and agitated. She also states that she has had thoughts of suicide. She of...
eligible ages (years): 18.0-65.0, Agitation Male and female patients between the ages of 18-65 years, inclusive Patients (or legal representative) willing and able to provide written Informed Consent Form Psychiatric patients already diagnosed of schizophrenia or bipolar disorder, according to the Diagnostic and Stati...
0
A 26-year-old obese woman with a history of bipolar disorder complains that her recent struggles with her weight and eating have caused her to feel depressed. She states that she has recently had difficulty sleeping and feels excessively anxious and agitated. She also states that she has had thoughts of suicide. She of...
eligible ages (years): 18.0-999.0, Insomnia Bipolar Disorder Adult outpatients meeting Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition, Text Revision (DSM-IV-TR) for bipolar I disorder (296.70), bipolar II disorder (296.89), or bipolar disorder not otherwise specified (296.80), with concurrent in...
0
A 26-year-old obese woman with a history of bipolar disorder complains that her recent struggles with her weight and eating have caused her to feel depressed. She states that she has recently had difficulty sleeping and feels excessively anxious and agitated. She also states that she has had thoughts of suicide. She of...
eligible ages (years): 18.0-65.0, Major Depressive Disorder Bipolar I Disorder Bipolar II Disorder Bipolar Depression Suicidal Ideation Provision of written informed consent [MDD stream only] Diagnosis of major depressive disorder, currently depressed as determined by DSM-IV diagnostic (confirmed using the MINI) [BD s...
0
A 26-year-old obese woman with a history of bipolar disorder complains that her recent struggles with her weight and eating have caused her to feel depressed. She states that she has recently had difficulty sleeping and feels excessively anxious and agitated. She also states that she has had thoughts of suicide. She of...
eligible ages (years): 18.0-64.0, Depression Alcoholism Drug Abuse African American English speaking Diagnosis of Bipolar Disorder (BD) Able to provide written informed consent Cognitive impairments Acutely psychotic Medically unstable History of schizophrenia spectrum disorder History of mood incongruent psychotic s...
2
A 26-year-old obese woman with a history of bipolar disorder complains that her recent struggles with her weight and eating have caused her to feel depressed. She states that she has recently had difficulty sleeping and feels excessively anxious and agitated. She also states that she has had thoughts of suicide. She of...
eligible ages (years): 18.0-999.0, Healthy Volunteers Male or female study participants, aged above 18 years-old; women cannot be pregnant or breastfeeding Body mass index (BMI) greater than or equal to 19 and less than or equal to 28.75 Kg/m2 Good health conditions or without significant diseases, according to best m...
0
A 62-year-old man sees a neurologist for progressive memory loss and jerking movements of the lower extremities. Neurologic examination confirms severe cognitive deficits and memory dysfunction. An electroencephalogram shows generalized periodic sharp waves. Neuroimaging studies show moderately advanced cerebral atroph...
eligible ages (years): 18.0-999.0, HIV Infections You may be eligible for this study if you Are HIV-positive Are at least 18 years old Have symptoms of AIDS dementia including forgetfulness, loss of concentration, slow mental processing, or a loss of muscle control Have been on stable anti-HIV drug therapy for the pas...
1