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A 65 yo African-American male with shortness of breath related to exertion that has been worsening over the past three weeks. He also has difficulty breathing when lying flat and has started using two to three extra pillows at night. Significant physical exam findings include bibasilar lung crackles, pitting ankle edem...
eligible ages (years): 0.0-999.0, Heart Failure EF <40%, getting majority care at the VA, not enrolled in another CHF study, ability to read English
2
A 65 yo African-American male with shortness of breath related to exertion that has been worsening over the past three weeks. He also has difficulty breathing when lying flat and has started using two to three extra pillows at night. Significant physical exam findings include bibasilar lung crackles, pitting ankle edem...
eligible ages (years): 0.0-999.0, Cardiovascular Diseases Heart Diseases Heart Failure Coronary Disease Diabetes Mellitus Hypertension Obesity
0
A 65 yo African-American male with shortness of breath related to exertion that has been worsening over the past three weeks. He also has difficulty breathing when lying flat and has started using two to three extra pillows at night. Significant physical exam findings include bibasilar lung crackles, pitting ankle edem...
eligible ages (years): 18.0-999.0, Metastatic Cancer Newly diagnosed supratentorial solitary brain metastasis by enhanced MRI or CT scan Resectable disease Histological evidence of metastatic carcinoma by intraoperative pathology No primary lymphoma, germ cell carcinoma, or small cell lung cancer Age and over Performa...
0
A 65 yo African-American male with shortness of breath related to exertion that has been worsening over the past three weeks. He also has difficulty breathing when lying flat and has started using two to three extra pillows at night. Significant physical exam findings include bibasilar lung crackles, pitting ankle edem...
eligible ages (years): 65.0-999.0, Brain Infarction Hypertension Patients with essential hypertension (systolic blood pressure>=140 mmHg and/or diastolic blood pressure>=90, or treated with antihypertensive drugs) Patients with any finding of stroke, silent brain infarction, and white matter lesion on magnetic resonan...
0
A 65 yo African-American male with shortness of breath related to exertion that has been worsening over the past three weeks. He also has difficulty breathing when lying flat and has started using two to three extra pillows at night. Significant physical exam findings include bibasilar lung crackles, pitting ankle edem...
eligible ages (years): 20.0-79.0, Hypertension Ischemic Heart Disease Congestive Heart Failure Clinical diagnosis of hypertension, ischemic heart disease and congestive heart failure Pregnancy Severe renal damage Severe liver damage Acute myocardial infarction
2
A 65 yo African-American male with shortness of breath related to exertion that has been worsening over the past three weeks. He also has difficulty breathing when lying flat and has started using two to three extra pillows at night. Significant physical exam findings include bibasilar lung crackles, pitting ankle edem...
eligible ages (years): 20.0-79.0, Hypertension Ischemic Heart Disease Congestive Heart Failure Stroke Clinical diagnosis of hypertension Clinical diagnosis of one or more risk factors, such as diabetes, smoking habit, lipid metabolism abnormality, history of ischemic heart disease (IHD) or cerebrovascular disease, obe...
0
A 65 yo African-American male with shortness of breath related to exertion that has been worsening over the past three weeks. He also has difficulty breathing when lying flat and has started using two to three extra pillows at night. Significant physical exam findings include bibasilar lung crackles, pitting ankle edem...
eligible ages (years): 18.0-999.0, Congestive Heart Failure, Atrial Fibrillation Patient is willing and able to comply with the protocol Patient is willing to sign written informed consent Patient is expected to remain available for Follow-up visits Patient age is 18 years and older patient is on a stable medication r...
1
A 65 yo African-American male with shortness of breath related to exertion that has been worsening over the past three weeks. He also has difficulty breathing when lying flat and has started using two to three extra pillows at night. Significant physical exam findings include bibasilar lung crackles, pitting ankle edem...
eligible ages (years): 18.0-999.0, Heart Failure, Congestive Renal Insufficiency Stable congestive heart failure Impaired renal function Taking oral loop diuretic Acutely decompensated (unstable) and end stage heart failure Diuretics other than loop diuretics Pregnant or nursing Inability to follow instructions Parti...
0
A 65 yo African-American male with shortness of breath related to exertion that has been worsening over the past three weeks. He also has difficulty breathing when lying flat and has started using two to three extra pillows at night. Significant physical exam findings include bibasilar lung crackles, pitting ankle edem...
eligible ages (years): 18.0-999.0, Heart Failure, Congestive Patients with heart failure treated with beta-blocker; hospitalisation for heart failure worsening with pulmonary oedema Left ventricular ejection fraction less than 40% Indication of intravenous positive inotropic treatment Indication to withdraw beta-bloc...
2
A 65 yo African-American male with shortness of breath related to exertion that has been worsening over the past three weeks. He also has difficulty breathing when lying flat and has started using two to three extra pillows at night. Significant physical exam findings include bibasilar lung crackles, pitting ankle edem...
eligible ages (years): 65.0-999.0, Heart Failure, Congestive All new residents to participating long-term care facilities Age 65 or over Residing in any long-term care facility for more than 8 weeks Inability or refusal to obtain informed consent Palliative diagnosis and not expected to survive 6 weeks Residents admi...
0
A 65 yo African-American male with shortness of breath related to exertion that has been worsening over the past three weeks. He also has difficulty breathing when lying flat and has started using two to three extra pillows at night. Significant physical exam findings include bibasilar lung crackles, pitting ankle edem...
eligible ages (years): 0.0-18.0, Dilated Cardiomyopathy Pediatric Diagnosed with dilated cardiomyopathy normal heart anatomy or those with repaired congenital defects that have a 4 chambered heart referred for a Biventricular pacemaker implantation or upgrade with the diagnosis of dilated cardiomyopathy or for an echo...
1
A 65 yo African-American male with shortness of breath related to exertion that has been worsening over the past three weeks. He also has difficulty breathing when lying flat and has started using two to three extra pillows at night. Significant physical exam findings include bibasilar lung crackles, pitting ankle edem...
eligible ages (years): 18.0-80.0, Heart Failure, Congestive Congestive heart failure patients due to any cause Patients with normal cortical function Congestive heart failure patients who are on diuretic therapy Clinically stable and body weight maintained the same for at least 3 days without signs of fluid retention ...
1
A 65 yo African-American male with shortness of breath related to exertion that has been worsening over the past three weeks. He also has difficulty breathing when lying flat and has started using two to three extra pillows at night. Significant physical exam findings include bibasilar lung crackles, pitting ankle edem...
eligible ages (years): 18.0-999.0, Symptomatic Decompensated Congestive Heart Failure Congestive Heart Failure in Acute Coronary Syndrome Patients with dyspnea (difficulty breathing and shortness of breath) at rest, while supine, or immediately upon minimal activity such as talking, eating, or bathing having evidence ...
2
A 65 yo African-American male with shortness of breath related to exertion that has been worsening over the past three weeks. He also has difficulty breathing when lying flat and has started using two to three extra pillows at night. Significant physical exam findings include bibasilar lung crackles, pitting ankle edem...
eligible ages (years): 16.0-999.0, Leukemia Diagnosis of acute myeloid leukemia Previously untreated disease Previous hydroxyurea and/or corticosteroids are acceptable No preexisting history of a hematologic disorder Myelodysplastic features allowed No acute leukemia secondary to previous therapy No leukemic meningiti...
0
A 65 yo African-American male with shortness of breath related to exertion that has been worsening over the past three weeks. He also has difficulty breathing when lying flat and has started using two to three extra pillows at night. Significant physical exam findings include bibasilar lung crackles, pitting ankle edem...
eligible ages (years): 18.0-999.0, Heart Failure Symptomatic heart failure and indication for cardiac resynchronization therapy (CRT), Hemodynamic stability with documented intolerance to beta-blocker therapy or treatment with beta-blocking agents at sub-optimal dosages (<25% of optimal dosage) chronic atrial fibrill...
1
A 65 yo African-American male with shortness of breath related to exertion that has been worsening over the past three weeks. He also has difficulty breathing when lying flat and has started using two to three extra pillows at night. Significant physical exam findings include bibasilar lung crackles, pitting ankle edem...
eligible ages (years): 0.0-999.0, Lung Cancer Patients must be enrolled in the trial: "A Phase I/II Trial of Neoadjuvant Paclitaxel, Carboplatin and OSI-774 (Tarceva) with Concurrent Accelerated Hyperfractionation Radiation Followed by Maintenance Therapy with OSI-774 for Stage III Non-Small Cell Lung Cancer," Princip...
0
A 65 yo African-American male with shortness of breath related to exertion that has been worsening over the past three weeks. He also has difficulty breathing when lying flat and has started using two to three extra pillows at night. Significant physical exam findings include bibasilar lung crackles, pitting ankle edem...
eligible ages (years): 30.0-999.0, Congestive Heart Failure (CHF) Physician diagnosed CHF Member of Kaiser Permanente Georgia
2
A 65 yo African-American male with shortness of breath related to exertion that has been worsening over the past three weeks. He also has difficulty breathing when lying flat and has started using two to three extra pillows at night. Significant physical exam findings include bibasilar lung crackles, pitting ankle edem...
eligible ages (years): 18.0-90.0, Congestive Heart Failure Patients will be recruited from the cardiology clinic at Hennepin County Medical Center. Patients are eligible for the study if they are Older than 18 Not pregnant Have heart failure with worsening hypervolemia despite oral diuretics Have at least two of the f...
1
A 65 yo African-American male with shortness of breath related to exertion that has been worsening over the past three weeks. He also has difficulty breathing when lying flat and has started using two to three extra pillows at night. Significant physical exam findings include bibasilar lung crackles, pitting ankle edem...
eligible ages (years): 0.0-999.0, Heart Failure Hospitalized for episode of worsening heart failure as primary cause of admission or significant heart failure symptoms that develop during the hospitalization when the initial reason for admission was not heart failure Systolic dysfunction (LVEF < 40%) or heart failure ...
2
A 65 yo African-American male with shortness of breath related to exertion that has been worsening over the past three weeks. He also has difficulty breathing when lying flat and has started using two to three extra pillows at night. Significant physical exam findings include bibasilar lung crackles, pitting ankle edem...
eligible ages (years): 20.0-999.0, Congestive Heart Failure Clinical diagnosis of heart failure based on a slight modification of the Framingham as previously described within 6 months before the entry Current status of heart failure is NYHA II or III Currently, loop diuretic(s) is (are) administered No change in base...
1
A 65 yo African-American male with shortness of breath related to exertion that has been worsening over the past three weeks. He also has difficulty breathing when lying flat and has started using two to three extra pillows at night. Significant physical exam findings include bibasilar lung crackles, pitting ankle edem...
eligible ages (years): 18.0-80.0, Hypertension African-American males and females current diagnosis of type 2 diabetes documented by medical history mean sitting diastolic blood pressure of ≥ 90 and ≤ 110 mm Hg HbA1C ≤ 9.5% having unilateral or bilateral renal artery stenosis having clinically significant cardiac dys...
0
A 65 yo African-American male with shortness of breath related to exertion that has been worsening over the past three weeks. He also has difficulty breathing when lying flat and has started using two to three extra pillows at night. Significant physical exam findings include bibasilar lung crackles, pitting ankle edem...
eligible ages (years): 0.0-999.0, Heart Failure, Congestive primary hospitalization with heart failure and LVEF < 40% patient informed consent has been obtained absence of pulmonary congestion age > 18 years End-stage renal or hepatic disease Acute myocardial infarction as primary diagnosis during index hospitalizati...
0
A 65 yo African-American male with shortness of breath related to exertion that has been worsening over the past three weeks. He also has difficulty breathing when lying flat and has started using two to three extra pillows at night. Significant physical exam findings include bibasilar lung crackles, pitting ankle edem...
eligible ages (years): 45.0-999.0, Congestive Heart Failure Age over 45 years old CHF class II or III with LVEF<40% Hospitalized at least once for CHF deterioration over previous 12 month period Able and willing to cooperate with this trial for at least a 3 month period Home close to participating center Recent (with...
1
A 65 yo African-American male with shortness of breath related to exertion that has been worsening over the past three weeks. He also has difficulty breathing when lying flat and has started using two to three extra pillows at night. Significant physical exam findings include bibasilar lung crackles, pitting ankle edem...
eligible ages (years): 0.0-999.0, Prostate Cancer Histologically confirmed adenocarcinoma of the prostate meeting any of the following for high-risk disease Clinical stage II or III (T2b, T2c, or T3 with any grade or prostate-specific antigen [PSA]) Gleason score 7 (4+3 only) or ≥ 8 (any stage or PSA) Serum PSA ≥ 10 n...
0
A 65 yo African-American male with shortness of breath related to exertion that has been worsening over the past three weeks. He also has difficulty breathing when lying flat and has started using two to three extra pillows at night. Significant physical exam findings include bibasilar lung crackles, pitting ankle edem...
eligible ages (years): 18.0-99.0, Congestive Heart Failure NYHA III-IV QRS > 120 msec On medical therapy, but beta blocker dose not @ target (carvedilol 25 bid, metoprolol succinate 200 qd) QRS < 120 msec On target beta blocker dose
1
A 65 yo African-American male with shortness of breath related to exertion that has been worsening over the past three weeks. He also has difficulty breathing when lying flat and has started using two to three extra pillows at night. Significant physical exam findings include bibasilar lung crackles, pitting ankle edem...
eligible ages (years): 18.0-999.0, Heart Diseases Advanced HF (Stage D or advanced Stage C HF) with symptoms of dyspnea at rest or with minimal exertion systolic dysfunction or preserved systolic function ("diastolic heart failure") Outpatient care setting (office, clinic or home hospice) Patient already receiving opt...
1
A 65 yo African-American male with shortness of breath related to exertion that has been worsening over the past three weeks. He also has difficulty breathing when lying flat and has started using two to three extra pillows at night. Significant physical exam findings include bibasilar lung crackles, pitting ankle edem...
eligible ages (years): 20.0-999.0, Obstructive Sleep Apnea Syndrome Obstructive sleep apnea syndrome based on symptoms and a sleep study Sleep disorders other than obstructive sleep apnea syndrome Other than mild, stable cardiovascular disease Other than mild lung disease Chronic rhinitis, previous uvulopalatopharyng...
0
A 65 yo African-American male with shortness of breath related to exertion that has been worsening over the past three weeks. He also has difficulty breathing when lying flat and has started using two to three extra pillows at night. Significant physical exam findings include bibasilar lung crackles, pitting ankle edem...
eligible ages (years): 18.0-999.0, Diabetes Mellitus Females of childbearing potential must be using appropriate birth during the entire duration of the study or must be surgically sterile Subjects with a clear diagnosis of type 2 diabetes mellitus using diagnostic of the American Diabetes Association who have been ta...
0
A 65 yo African-American male with shortness of breath related to exertion that has been worsening over the past three weeks. He also has difficulty breathing when lying flat and has started using two to three extra pillows at night. Significant physical exam findings include bibasilar lung crackles, pitting ankle edem...
eligible ages (years): 18.0-90.0, Heart Failure HF by Framingham At least one admission to hospital for HF within the last 180 days New York Heart Association Class II thru IV Echocardiographic criteria:At least moderate diastolic dysfunction, Ejection fraction >45% Creatinine clearance <40 mls/min/1.73m2 Potassium >...
1
A 65 yo African-American male with shortness of breath related to exertion that has been worsening over the past three weeks. He also has difficulty breathing when lying flat and has started using two to three extra pillows at night. Significant physical exam findings include bibasilar lung crackles, pitting ankle edem...
eligible ages (years): 18.0-999.0, Heart Failure, Congestive Received or is eligible to receive a principal hospital discharge diagnosis of HF or decompensated HF is present as determined clinically by the patient care team Heart Failure is present as a co-morbid condition, but is not a principal focus of diagnosis o...
2
A 65 yo African-American male with shortness of breath related to exertion that has been worsening over the past three weeks. He also has difficulty breathing when lying flat and has started using two to three extra pillows at night. Significant physical exam findings include bibasilar lung crackles, pitting ankle edem...
eligible ages (years): 18.0-999.0, Congestive Heart Failure age18 or older primary diagnosis of CHF in the Emergency Department admission to the hospital or transfer to the Observation Unit minors, prisoners,pregnant women,unable to provide consent unstable angina or acute myocardial infarction in the ED dialysis dep...
2
A 65 yo African-American male with shortness of breath related to exertion that has been worsening over the past three weeks. He also has difficulty breathing when lying flat and has started using two to three extra pillows at night. Significant physical exam findings include bibasilar lung crackles, pitting ankle edem...
eligible ages (years): 18.0-80.0, Rheumatoid Arthritis Interstitial Pneumonia Diagnosis of RA according to the revised 1987 American Rheumatism Association Absence of clinical features suggesting infection, neoplasm, sarcoidosis, interstitial lung disease other than UIP or NSIP, other collagen vascular disease, or exp...
0
A 65 yo African-American male with shortness of breath related to exertion that has been worsening over the past three weeks. He also has difficulty breathing when lying flat and has started using two to three extra pillows at night. Significant physical exam findings include bibasilar lung crackles, pitting ankle edem...
eligible ages (years): 18.0-999.0, Atrial Fibrillation Congestive Heart Failure Left ventricular ejection fraction </=35% as measured by nuclear imaging, echocardiography, or cardiac angiography within 6 months preceding enrollment. If the patient has had a myocardial infarction or heart surgery during this period, th...
1
A 65 yo African-American male with shortness of breath related to exertion that has been worsening over the past three weeks. He also has difficulty breathing when lying flat and has started using two to three extra pillows at night. Significant physical exam findings include bibasilar lung crackles, pitting ankle edem...
eligible ages (years): 75.0-999.0, Heart Failure Acute exacerbation of chronic heart failure Age over 75 Appropriate care supervision at home Telephone connection Living in the hospital-at-home catchment area and informed consent Absence of family and social support Patients who need mechanical ventilation Severe dem...
0
A 65 yo African-American male with shortness of breath related to exertion that has been worsening over the past three weeks. He also has difficulty breathing when lying flat and has started using two to three extra pillows at night. Significant physical exam findings include bibasilar lung crackles, pitting ankle edem...
eligible ages (years): 18.0-999.0, Heart Failure diagnosis of NYHA I, II or III heart failure (as identified by any of the following physical findings of heart failure (jugular venous distension, crackles, edema, S3); pulmonary edema on chest x-ray; BNP > 100 pg/ml; or at least two of the following symptoms: paroxysma...
0
A 65 yo African-American male with shortness of breath related to exertion that has been worsening over the past three weeks. He also has difficulty breathing when lying flat and has started using two to three extra pillows at night. Significant physical exam findings include bibasilar lung crackles, pitting ankle edem...
eligible ages (years): 18.0-999.0, Congestive Heart Failure Male or female aged 18 or above Congestive Heart Failure with symptoms for more than 4 weeks before starting study Provision of informed consent Current low blood pressure with symptoms Liver disease considered significant by the study doctor Pregnant or lac...
0
A 65 yo African-American male with shortness of breath related to exertion that has been worsening over the past three weeks. He also has difficulty breathing when lying flat and has started using two to three extra pillows at night. Significant physical exam findings include bibasilar lung crackles, pitting ankle edem...
eligible ages (years): 18.0-999.0, Right Sided Cardiac Failure Patients must have right sided failure secondary to right ventricular dysfunction, pulmonary hypertension, or tricuspid regurgitation Age greater than 18 years of age Right heart catheterization within the last year to rule out left-sided failure Evidence ...
1
A 65 yo African-American male with shortness of breath related to exertion that has been worsening over the past three weeks. He also has difficulty breathing when lying flat and has started using two to three extra pillows at night. Significant physical exam findings include bibasilar lung crackles, pitting ankle edem...
eligible ages (years): 0.0-999.0, Heart Failure chronic stable heart failure renal dysfunction or under treatment with antidiabetic agents
0
A 65 yo African-American male with shortness of breath related to exertion that has been worsening over the past three weeks. He also has difficulty breathing when lying flat and has started using two to three extra pillows at night. Significant physical exam findings include bibasilar lung crackles, pitting ankle edem...
eligible ages (years): 21.0-90.0, Heart Failure Male or female patient's > 21 years of age with a severe congestive heart failure (New York Heart Association class III or IV) requiring an immediate administration of intravenous vasodilators drugs, oxygen therapy, and no less than 160 mg of intravenous furosemide were ...
1
A 65 yo African-American male with shortness of breath related to exertion that has been worsening over the past three weeks. He also has difficulty breathing when lying flat and has started using two to three extra pillows at night. Significant physical exam findings include bibasilar lung crackles, pitting ankle edem...
eligible ages (years): 40.0-999.0, Hypertension Self-identifies as African American Resides in Washington, DC or surrounding communities Has stage I hypertension, defined as systolic blood pressure between 140 and 159 mm Hg and/or diastolic blood pressure between 90 and 99 mm Hg, on average, without taking antihyperte...
0
A 65 yo African-American male with shortness of breath related to exertion that has been worsening over the past three weeks. He also has difficulty breathing when lying flat and has started using two to three extra pillows at night. Significant physical exam findings include bibasilar lung crackles, pitting ankle edem...
eligible ages (years): 18.0-65.0, Hyperglycemia Obese African American subjects (BMI equal or greater than 30) age 18-65 patients with a history of diabetic ketoacidosis as defined by the ADA patients admitted with hyperglycemia but without ketoacidosis (BG greater than 400ml/dl without evidence of ketosis/ketones obe...
0
A 65 yo African-American male with shortness of breath related to exertion that has been worsening over the past three weeks. He also has difficulty breathing when lying flat and has started using two to three extra pillows at night. Significant physical exam findings include bibasilar lung crackles, pitting ankle edem...
eligible ages (years): 20.0-95.0, Pulmonary Edema Patients in the intensive care unit using ventilator Asthma, COPD, non-ventilated patients
0
A 65 yo African-American male with shortness of breath related to exertion that has been worsening over the past three weeks. He also has difficulty breathing when lying flat and has started using two to three extra pillows at night. Significant physical exam findings include bibasilar lung crackles, pitting ankle edem...
eligible ages (years): 18.0-999.0, Heart Failure Patients with stable congestive heart failure on a prescription for diuretic drugs Acute heart failure Foreseeable need for further changes in medication Current medication containing vitamins Patients with a creatinine above 250 μmol/l
0
A 65 yo African-American male with shortness of breath related to exertion that has been worsening over the past three weeks. He also has difficulty breathing when lying flat and has started using two to three extra pillows at night. Significant physical exam findings include bibasilar lung crackles, pitting ankle edem...
eligible ages (years): 50.0-999.0, Congestive Heart Failure subjects will be at least 50 years of age women who are post-menopausal clinical evidence of congestive heart failure, with ongoing management by conventional medical therapy a left ventricular ejection fraction below 40% as measured by echocardiogram perform...
0
A 65 yo African-American male with shortness of breath related to exertion that has been worsening over the past three weeks. He also has difficulty breathing when lying flat and has started using two to three extra pillows at night. Significant physical exam findings include bibasilar lung crackles, pitting ankle edem...
eligible ages (years): 18.0-999.0, Congestive Heart Failure Hypovitaminosis D Hypomagnesemia Hyperparathyroidism congestive heart failure pregnant hospitalized within one month taking calcium, vitamin D or magnesium supplements proteinuria > 1g/24h creatinine clearance <35 (MDRD)
2
A 65 yo African-American male with shortness of breath related to exertion that has been worsening over the past three weeks. He also has difficulty breathing when lying flat and has started using two to three extra pillows at night. Significant physical exam findings include bibasilar lung crackles, pitting ankle edem...
eligible ages (years): 18.0-999.0, Heart Failure Patients with documented heart failure (NYHA class II-IV) Use of both ACEi and ARB, ACEi and DRI, ARB and DRI treatment, or all three medications at Screening
1
A 65 yo African-American male with shortness of breath related to exertion that has been worsening over the past three weeks. He also has difficulty breathing when lying flat and has started using two to three extra pillows at night. Significant physical exam findings include bibasilar lung crackles, pitting ankle edem...
eligible ages (years): 18.0-999.0, Congestive Heart Failure Subject eligible for implantation of a CRT-D device according to current available guidelines for cardiac resynchronization therapy Subject has severe heart failure (NYHA Class III or IV) Subject has experienced at least one heart failure event within six mon...
1
A 65 yo African-American male with shortness of breath related to exertion that has been worsening over the past three weeks. He also has difficulty breathing when lying flat and has started using two to three extra pillows at night. Significant physical exam findings include bibasilar lung crackles, pitting ankle edem...
eligible ages (years): 18.0-999.0, Heart Failure Normal subject without history, signs-symptoms or diagnosis of heart failure Age over 18 and willing and able to provide informed consent Known allergy to electrode gel and medical adhesive used on electrocardiographic electrodes Pregnancy (as any effect of this device...
1
A 65 yo African-American male with shortness of breath related to exertion that has been worsening over the past three weeks. He also has difficulty breathing when lying flat and has started using two to three extra pillows at night. Significant physical exam findings include bibasilar lung crackles, pitting ankle edem...
eligible ages (years): 18.0-80.0, Sleep Apnea, Central Men and women 18 to 79 years of age who have New York Heart Association (NYHA) functional class I through IV heart failure due to ischemic, hypertensive, or idiopathic dilated cardiomyopathy and whose condition had been stabilized by means of optimal medical thera...
1
A 65 yo African-American male with shortness of breath related to exertion that has been worsening over the past three weeks. He also has difficulty breathing when lying flat and has started using two to three extra pillows at night. Significant physical exam findings include bibasilar lung crackles, pitting ankle edem...
eligible ages (years): 18.0-999.0, Hypertension currently taking an ACEi, ARB or both no change in these medications during the two weeks prior to study enrollment scheduled for non-cardiac surgery requiring regional or general anesthesia minimum overnight anticipated length of stay age ≥18 years explicit instruction...
0
A 65 yo African-American male with shortness of breath related to exertion that has been worsening over the past three weeks. He also has difficulty breathing when lying flat and has started using two to three extra pillows at night. Significant physical exam findings include bibasilar lung crackles, pitting ankle edem...
eligible ages (years): 60.0-999.0, Heart Failure Age greater than or equal to 60 years of age Symptoms of congestive heart failure Able to understand and give informed consent Age <60 years Does not have CHF Significant change in cardiac medication <3 weeks Myocardial infarction <3 weeks CABG surgery <3 months Angina...
1
A 65 yo African-American male with shortness of breath related to exertion that has been worsening over the past three weeks. He also has difficulty breathing when lying flat and has started using two to three extra pillows at night. Significant physical exam findings include bibasilar lung crackles, pitting ankle edem...
eligible ages (years): 18.0-999.0, Acute Decompensated Heart Failure >18 years old Severe systolic heart failure with ejection fraction <40% And Hospitalisation for decompensated heart failure And New York Heart Association (NYHA) III or IV And 1 of the following Jugular vein distension>6cm Tissue Doppler mitral annul...
2
A 65 yo African-American male with shortness of breath related to exertion that has been worsening over the past three weeks. He also has difficulty breathing when lying flat and has started using two to three extra pillows at night. Significant physical exam findings include bibasilar lung crackles, pitting ankle edem...
eligible ages (years): 21.0-999.0, Heart Failure hospitalized with admitting diagnosis of heart failure in prior 8 weeks self-identified as African American community-dwelling (i.e., not in a long-term care facility) residence within a predefined radius in Baltimore City working telephone in their home provide signed ...
2
A 65 yo African-American male with shortness of breath related to exertion that has been worsening over the past three weeks. He also has difficulty breathing when lying flat and has started using two to three extra pillows at night. Significant physical exam findings include bibasilar lung crackles, pitting ankle edem...
eligible ages (years): 65.0-999.0, Heart Failure Chronic Obstructive Pulmonary Disease patients aged 65 years and older must have a minimum of three chronic or vitality threatening diseases and/or use five or more medical drugs chronically in the last year must have dyspnea and/or reduced exercise tolerance (scored by...
1
A 65 yo African-American male with shortness of breath related to exertion that has been worsening over the past three weeks. He also has difficulty breathing when lying flat and has started using two to three extra pillows at night. Significant physical exam findings include bibasilar lung crackles, pitting ankle edem...
eligible ages (years): 19.0-999.0, Cesarean Section Pregnancy greater than 37 weeks gestation ASA (American Society of Anaesthesiologists) I and II classification of health. Class I a normal healthy patient and II a patient with mild systemic disease (i.e. mild asthma) Mothers presenting to the assessment unit with ru...
0
A 65 yo African-American male with shortness of breath related to exertion that has been worsening over the past three weeks. He also has difficulty breathing when lying flat and has started using two to three extra pillows at night. Significant physical exam findings include bibasilar lung crackles, pitting ankle edem...
eligible ages (years): 18.0-999.0, Overweight Obesity BMI of at least 25.0 self-identifies as Black or African-American able to do mild physical activity such as walking or chair exercises has insulin dependent diabetes is pregnant, nursing, or had a baby in the past 4 months has ever been treated for an eating disor...
0
A 65 yo African-American male with shortness of breath related to exertion that has been worsening over the past three weeks. He also has difficulty breathing when lying flat and has started using two to three extra pillows at night. Significant physical exam findings include bibasilar lung crackles, pitting ankle edem...
eligible ages (years): 70.0-999.0, Chronic Heart Failure Verified diagnosis of heart failure Left ventricle ejection fraction < 50 Stable medical treatment with Angiotensin Converting Enzyme blockers and Betareceptor blockers (if no contraindications) experience of fatigue according to the Multidimensional Fatigue Inv...
0
A 65 yo African-American male with shortness of breath related to exertion that has been worsening over the past three weeks. He also has difficulty breathing when lying flat and has started using two to three extra pillows at night. Significant physical exam findings include bibasilar lung crackles, pitting ankle edem...
eligible ages (years): 18.0-999.0, Chronic Heart Failure Advanced chronic heart failure (HF) will be defined as left ventricular ejection fraction less than 35%, creatinine less than 2 mg/dL, and CHF NY functional class III-IV for more than 3 months. Enrolled patients should be admitted to hospital due to heart failur...
2
A 65 yo African-American male with shortness of breath related to exertion that has been worsening over the past three weeks. He also has difficulty breathing when lying flat and has started using two to three extra pillows at night. Significant physical exam findings include bibasilar lung crackles, pitting ankle edem...
eligible ages (years): 18.0-999.0, Cardiovascular Diseases Cardiovascular Risk Factor African American adults > 18 years old
2
A 65 yo African-American male with shortness of breath related to exertion that has been worsening over the past three weeks. He also has difficulty breathing when lying flat and has started using two to three extra pillows at night. Significant physical exam findings include bibasilar lung crackles, pitting ankle edem...
eligible ages (years): 18.0-90.0, Bronchiectasis Bronchiolitis All patients with bronchiectasis or bronchiolitis All patients with severe lung disease other than bronchiectasis Active lung infection Active infection other site except the lung
0
A 65 yo African-American male with shortness of breath related to exertion that has been worsening over the past three weeks. He also has difficulty breathing when lying flat and has started using two to three extra pillows at night. Significant physical exam findings include bibasilar lung crackles, pitting ankle edem...
eligible ages (years): 20.0-999.0, Heart Failure, Congestive Subjects admitted to hospital with systolic heart failure(LVEF under 45%) in 2009 Subjects, age 20 or/and above Subjects admitted to hospital (emergency area, to internal medicine or to cardiology wards, CCU or intensive care) with dyspnea and verification o...
1
A 65 yo African-American male with shortness of breath related to exertion that has been worsening over the past three weeks. He also has difficulty breathing when lying flat and has started using two to three extra pillows at night. Significant physical exam findings include bibasilar lung crackles, pitting ankle edem...
eligible ages (years): 0.0-999.0, Congestive Heart Failure (CHF) Clinical diagnosis of heart failure at levels III and IV, according to the classification of the NYHA (New York Heart Association) for 3 months or more Clinical diagnosis of LVEF less than 50% or were on diuretic therapy for more than three months with a...
1
A 65 yo African-American male with shortness of breath related to exertion that has been worsening over the past three weeks. He also has difficulty breathing when lying flat and has started using two to three extra pillows at night. Significant physical exam findings include bibasilar lung crackles, pitting ankle edem...
eligible ages (years): 18.0-999.0, Acute Decompensated Heart Failure males and non-pregnant female patients over 18 years admitted to the hospital or treated in an outpatient heart failure clinic with the primary diagnosis of acute decompensated heart failure evidence of fluid overload more than 8 kg above their dry w...
2
A 65 yo African-American male with shortness of breath related to exertion that has been worsening over the past three weeks. He also has difficulty breathing when lying flat and has started using two to three extra pillows at night. Significant physical exam findings include bibasilar lung crackles, pitting ankle edem...
eligible ages (years): 18.0-999.0, Acute Heart Failure Clinical diagnosis of acute heart failure Admitted to the participating hospitals Patients with acute heart failure who are discharged from the emergency room without admission Patients transferred from non-registry hospital Failure to obtain informed consent
2
A 65 yo African-American male with shortness of breath related to exertion that has been worsening over the past three weeks. He also has difficulty breathing when lying flat and has started using two to three extra pillows at night. Significant physical exam findings include bibasilar lung crackles, pitting ankle edem...
eligible ages (years): 0.0-999.0, Juvenile Idiopathic Arthritis Subject has been diagnosed with JIA by a pediatric rheumatologist according to published criteria Person providing consent must be able to read English Subject (and/or parent/legal guardian) is able to provide informed consent and willing to comply with s...
0
A 65 yo African-American male with shortness of breath related to exertion that has been worsening over the past three weeks. He also has difficulty breathing when lying flat and has started using two to three extra pillows at night. Significant physical exam findings include bibasilar lung crackles, pitting ankle edem...
eligible ages (years): 65.0-79.0, Healthy Elderly Subject Pharmacokinetic of YM150 Healthy, as judged by the investigator or sub-investigator based on the results of physical examinations and all tests Body weight: male: ≥45.0 kg, <85.0 kg; female: ≥40.0 kg, <75.0 kg BMI (at screening): ≥17.6, <30.0 Use of any other ...
0
A 65 yo African-American male with shortness of breath related to exertion that has been worsening over the past three weeks. He also has difficulty breathing when lying flat and has started using two to three extra pillows at night. Significant physical exam findings include bibasilar lung crackles, pitting ankle edem...
eligible ages (years): 30.0-70.0, Cervical Spine Degenerative Disc Disease Fusion of Spine, Cervical Region Men and women between the age of 30 to 70 years Individuals who have consulted one of the five participating spine surgeons and are scheduled for ACF surgery at Texas Spine and Joint Hospital Surgical candidates...
0
A 65 yo African-American male with shortness of breath related to exertion that has been worsening over the past three weeks. He also has difficulty breathing when lying flat and has started using two to three extra pillows at night. Significant physical exam findings include bibasilar lung crackles, pitting ankle edem...
eligible ages (years): 18.0-999.0, Congestive Heart Failure Systolic Dysfunction Age =/or >18 Admitted to the Heart Failure Unit with acute decompensated heart failure Referred to the Congestive Heart Failure Disease Management Program Age<18 Mentally incapacitated Discharge to a skilled nursing facility
2
A 65 yo African-American male with shortness of breath related to exertion that has been worsening over the past three weeks. He also has difficulty breathing when lying flat and has started using two to three extra pillows at night. Significant physical exam findings include bibasilar lung crackles, pitting ankle edem...
eligible ages (years): 18.0-70.0, Sickle Cell Disease Sickle Cell Anemia Regadenoson ARM Diagnosis of sickle cell anemia confirmed by hemoglobin analysis Ages 18 to 70 years Subjects must have laboratory indices as outlined by the protocol Reliable IV access as determined by physician Sickle Cell Controls ARM Diagnosi...
0
A 65 yo African-American male with shortness of breath related to exertion that has been worsening over the past three weeks. He also has difficulty breathing when lying flat and has started using two to three extra pillows at night. Significant physical exam findings include bibasilar lung crackles, pitting ankle edem...
eligible ages (years): 18.0-999.0, Heart Failure History of chronic heart failure Admission for acute decompensated heart failure There is no prespecified criterion with respect to heart failure etiology and/or ejection fraction Receipt of an oral loop diuretic for at least 1 month before hospitalization, at a dose be...
1
A 65 yo African-American male with shortness of breath related to exertion that has been worsening over the past three weeks. He also has difficulty breathing when lying flat and has started using two to three extra pillows at night. Significant physical exam findings include bibasilar lung crackles, pitting ankle edem...
eligible ages (years): 18.0-75.0, Obstructive Sleep Apnoea males and females, age >18years and <75years, body-mass index (BMI) >18 and <40kg/m2, non-smokers, sleep apnoea with an ODI ≥15/h or sleep apnoea with an ODI ≥5/h plus an Epworth sleepiness score >10 morbid obesity (BMI>40kg/m2) or cachexia (BMI<18kg/m2), obe...
0
A 65 yo African-American male with shortness of breath related to exertion that has been worsening over the past three weeks. He also has difficulty breathing when lying flat and has started using two to three extra pillows at night. Significant physical exam findings include bibasilar lung crackles, pitting ankle edem...
eligible ages (years): 60.0-999.0, Heart Failure Patients 60 years of age or older Hospitalized with heart failure according to New York Heart Association (NYHA) class II-IV Left ventricular systolic dysfunction with an ejection fraction below 0.45, by echocardiography An acute myocardial infarction or unstable angin...
2
A 65 yo African-American male with shortness of breath related to exertion that has been worsening over the past three weeks. He also has difficulty breathing when lying flat and has started using two to three extra pillows at night. Significant physical exam findings include bibasilar lung crackles, pitting ankle edem...
eligible ages (years): 40.0-80.0, Hypertension Untreated hypertension: systolic BP ≥ 140 or diastolic BP ≥ 90 mmHg or Treated hypertension Current heart failure symptoms with NYHA class II Evidence of diastolic dysfunction showing any 2 of the following E/E' > 10, LV posterior wall thickness > 11 mm, BNP level > 40 pg...
0
A 65 yo African-American male with shortness of breath related to exertion that has been worsening over the past three weeks. He also has difficulty breathing when lying flat and has started using two to three extra pillows at night. Significant physical exam findings include bibasilar lung crackles, pitting ankle edem...
eligible ages (years): 18.0-999.0, Heart Failure, Congestive Cardiovascular Diseases Heart Diseases (PCP) 1. Provider must be the health professional who is managing the potential patient enrollee's heart failure medication(s) (Patients) Participant has been diagnosed with Heart Failure (HF) Self reported family incom...
1
A 65 yo African-American male with shortness of breath related to exertion that has been worsening over the past three weeks. He also has difficulty breathing when lying flat and has started using two to three extra pillows at night. Significant physical exam findings include bibasilar lung crackles, pitting ankle edem...
eligible ages (years): 18.0-90.0, Cardiovascular Diseases Age between 18 years and 90 years old Clinically significant functional mitral regurgitation (moderate-to-severe or severe mitral regurgitation), as defined by European Association of Echocardiography, within 90 days prior to randomization and confirmed by the ...
1
A 65 yo African-American male with shortness of breath related to exertion that has been worsening over the past three weeks. He also has difficulty breathing when lying flat and has started using two to three extra pillows at night. Significant physical exam findings include bibasilar lung crackles, pitting ankle edem...
eligible ages (years): 18.0-80.0, Constipation Age 18-80 constipation defined by the Rome II Past history of abdominal surgery past history of diabetes mellitus past history of hypothyroidism past history of inflammatory bowel disease past history of significant psychiatric disturbances past history of drug abuse pas...
0
A 65 yo African-American male with shortness of breath related to exertion that has been worsening over the past three weeks. He also has difficulty breathing when lying flat and has started using two to three extra pillows at night. Significant physical exam findings include bibasilar lung crackles, pitting ankle edem...
eligible ages (years): 60.0-999.0, Heart Failure Men and women ≥ 60 years Admission to hospital for worsening HF History of uncontrolled hypertension Severe valve disease End-stage (Stage D) HF, including treatment with chronic ionotropic drugs or left ventricular assist device support Advanced malignancy or other me...
2
A 65 yo African-American male with shortness of breath related to exertion that has been worsening over the past three weeks. He also has difficulty breathing when lying flat and has started using two to three extra pillows at night. Significant physical exam findings include bibasilar lung crackles, pitting ankle edem...
eligible ages (years): 18.0-999.0, Acute Heart Failure Left Ventricular Dysfunction > 18 years of age Hospital admission for acute heart failure as defined by the presence of acute dyspnea and the presence of clinical signs of heart failure on physical examination Where available, NT-proBNP >900 pg/ml, >1800 pg/ml if ...
1
A 65 yo African-American male with shortness of breath related to exertion that has been worsening over the past three weeks. He also has difficulty breathing when lying flat and has started using two to three extra pillows at night. Significant physical exam findings include bibasilar lung crackles, pitting ankle edem...
eligible ages (years): 18.0-50.0, Obstructive Sleep Apnea Pre-menopausal females aged ≥ 18 years Current positive airway pressure (PAP)(CPAP or APAP) therapy user with 'current' defined as on PAP therapy for at least 1 month prior to study entry Diagnostic PSG available Diagnosis of mild-moderate OSA (AHI ≤ 30) Partic...
0
A 65 yo African-American male with shortness of breath related to exertion that has been worsening over the past three weeks. He also has difficulty breathing when lying flat and has started using two to three extra pillows at night. Significant physical exam findings include bibasilar lung crackles, pitting ankle edem...
eligible ages (years): 18.0-95.0, Heart Rate Control in ICD Patients With Heart Failure Age ≥ 18 years Patients with stable chronic heart failure implanted with mono-cameral or bicameral ICD with a home monitoring remote control Moderate to severe left ventricular dysfunction (FE ≤ 40%) Any cause of heart failure was ...
0
A 65 yo African-American male with shortness of breath related to exertion that has been worsening over the past three weeks. He also has difficulty breathing when lying flat and has started using two to three extra pillows at night. Significant physical exam findings include bibasilar lung crackles, pitting ankle edem...
eligible ages (years): 18.0-999.0, Metabolic Syndrome Coronary Heart Disease Chronic Heart Failure Elderly healthy subjects : with no MetS and no-documented CHD, both males and females, aged>60 years will be included in the study, should they provide written informed consent and have a sufficient initial physical and ...
2
A 65 yo African-American male with shortness of breath related to exertion that has been worsening over the past three weeks. He also has difficulty breathing when lying flat and has started using two to three extra pillows at night. Significant physical exam findings include bibasilar lung crackles, pitting ankle edem...
eligible ages (years): 21.0-130.0, Heart Failure All 6 need to be met for enrollment of the patient in the study Primary diagnosis for hospitalization is decompensated heart failure established as the finding at admission of all 2 conditions listed below dyspnea or respiratory distress or tachypnea at rest or with min...
0
A 65 yo African-American male with shortness of breath related to exertion that has been worsening over the past three weeks. He also has difficulty breathing when lying flat and has started using two to three extra pillows at night. Significant physical exam findings include bibasilar lung crackles, pitting ankle edem...
eligible ages (years): 18.0-999.0, Acute Decompensated Heart Failure Heart Failure Patients ≥ 18 years of age and English-speaking who are admitted to the General Cardiology or Heart Failure Services at the University of North Carolina Hospitals with acute decompensated heart failure (ADHF) Patients deemed by the heal...
1
A 65 yo African-American male with shortness of breath related to exertion that has been worsening over the past three weeks. He also has difficulty breathing when lying flat and has started using two to three extra pillows at night. Significant physical exam findings include bibasilar lung crackles, pitting ankle edem...
eligible ages (years): 7.0-999.0, Limb Girdle Muscular Dystrophy Type 2D (LGMD2D) Subjects age 7 or older; cohort 1A must be adult and wheelchair-dependent Proven alpha-sarcoglycan deficiency by muscle biopsy or DNA testing Onset of weakness by 5 years age based on history of difficulty running, jumping and climbing s...
0
A 65 yo African-American male with shortness of breath related to exertion that has been worsening over the past three weeks. He also has difficulty breathing when lying flat and has started using two to three extra pillows at night. Significant physical exam findings include bibasilar lung crackles, pitting ankle edem...
eligible ages (years): 40.0-90.0, Congestive Heart Failure Congestive heart failure patients between tne ages 40 to 90,all stages of the disease non
2
A 65 yo African-American male with shortness of breath related to exertion that has been worsening over the past three weeks. He also has difficulty breathing when lying flat and has started using two to three extra pillows at night. Significant physical exam findings include bibasilar lung crackles, pitting ankle edem...
eligible ages (years): 20.0-75.0, Obstructive Sleep Apnoea (OSA) Confirmed OSA (at the time of original diagnosis) with an oxygen desaturation index (ODI) of >20/h Currently >20/h oxygen desaturations (≥4% dips) during an ambulatory nocturnal pulse oximetry performed on the last night of a 4-night period without CPAP ...
0
A 65 yo African-American male with shortness of breath related to exertion that has been worsening over the past three weeks. He also has difficulty breathing when lying flat and has started using two to three extra pillows at night. Significant physical exam findings include bibasilar lung crackles, pitting ankle edem...
eligible ages (years): 21.0-999.0, Congestive Heart Failure CHF Subjects: 21 years of age or greater, with clinically confirmed CHF or have presented to the clinical site with signs, symptoms and/or risk factors suggestive of heart failure Subjects with Potentially confounding comorbidities: Non-CHF subjects 21 years ...
1
A 65 yo African-American male with shortness of breath related to exertion that has been worsening over the past three weeks. He also has difficulty breathing when lying flat and has started using two to three extra pillows at night. Significant physical exam findings include bibasilar lung crackles, pitting ankle edem...
eligible ages (years): 18.0-999.0, Asthma Male or female patients aged >=18 years Uncontrolled asthma on medium doses of ICS+LABA with ACQ >=1.5 Pre-bronchodilator FEV1 ≥40% and <80% of their predicted normal value Pregnant or lactating women Diagnosis of COPD Patients treated for asthma exacerbations in the 4 weeks ...
0
A 65 yo African-American male with shortness of breath related to exertion that has been worsening over the past three weeks. He also has difficulty breathing when lying flat and has started using two to three extra pillows at night. Significant physical exam findings include bibasilar lung crackles, pitting ankle edem...
eligible ages (years): 75.0-999.0, Heart Failure years or older diagnosis of previous or new heart failure based on signs and symptoms as defined by the 'European Society of Cardiology guidelines on acute and chronic heart failure' diagnosis had to be confirmed by a recent echocardiogram not Dutch speaking treatment ...
0
A 65 yo African-American male with shortness of breath related to exertion that has been worsening over the past three weeks. He also has difficulty breathing when lying flat and has started using two to three extra pillows at night. Significant physical exam findings include bibasilar lung crackles, pitting ankle edem...
eligible ages (years): 18.0-999.0, Beta Blocker Intolerance; Congestive Heart Failure Patients on optimal therapy for heart failure (diuretics, ACE inhibitors and aldosterone antagonists), with stable dose in the previous month Successfully implanted with CRT-D according to current European Society of Cardiology (ESC)...
0
A 65 yo African-American male with shortness of breath related to exertion that has been worsening over the past three weeks. He also has difficulty breathing when lying flat and has started using two to three extra pillows at night. Significant physical exam findings include bibasilar lung crackles, pitting ankle edem...
eligible ages (years): 40.0-80.0, Chronic Obstructive Pulmonary Disease Male and female adults (40 ≤ age ≤ 80 years) with a diagnosis of COPD Current smokers or ex-smokers A post-bronchodilator FEV1 < 60% of the predicted normal value and a post-bronchodilator FEV1/FVC < 0.7 Positive response to the reversibility test...
0
A 65 yo African-American male with shortness of breath related to exertion that has been worsening over the past three weeks. He also has difficulty breathing when lying flat and has started using two to three extra pillows at night. Significant physical exam findings include bibasilar lung crackles, pitting ankle edem...
eligible ages (years): 18.0-999.0, Sleep Disordered Breathing Heart Failure Heart failure with reduced ejection fraction (<40%) Either no significant sleep disordered breathing or moderate to severe CSA Able to consent to the study Ambulatory Aged 18-100 years Patients on Non-Invasive Ventilation Predominant OSA Unab...
2
A 65 yo African-American male with shortness of breath related to exertion that has been worsening over the past three weeks. He also has difficulty breathing when lying flat and has started using two to three extra pillows at night. Significant physical exam findings include bibasilar lung crackles, pitting ankle edem...
eligible ages (years): 12.0-999.0, Gastroesophageal Reflux Disease GERD Gastroparesis Male or female Age 12 and older Symptoms or manifestations secondary to GERD (e.g., persistent esophagitis, heartburn, upper airway signs or symptoms or respiratory symptoms), gastrointestinal motility disorders such as nausea, vomit...
0
A 65 yo African-American male with shortness of breath related to exertion that has been worsening over the past three weeks. He also has difficulty breathing when lying flat and has started using two to three extra pillows at night. Significant physical exam findings include bibasilar lung crackles, pitting ankle edem...
eligible ages (years): 18.0-999.0, Acute Decompensated Heart Failure Congestive Heart Failure Compensated Age ≥ 18 years, AND Written informed consent by patient or nearest relative where appropriate, AND Either Referred for echocardiography, OR At least one typical symptom and one typical sign consistent with possibl...
2
A 65 yo African-American male with shortness of breath related to exertion that has been worsening over the past three weeks. He also has difficulty breathing when lying flat and has started using two to three extra pillows at night. Significant physical exam findings include bibasilar lung crackles, pitting ankle edem...
eligible ages (years): 18.0-75.0, Asthma History of asthma ≥ 5 years and diagnosed before 40 years old Uncontrolled asthma on low-medium doses of Inhaled CorticoSteroid (ICS) with ACQ (Asthma Control Questionnaire) ≥1.5 Pre-bronchodilator FEV1 ≥40% and <90% of their predicted normal value Positive reversibility test ...
0
A 65 yo African-American male with shortness of breath related to exertion that has been worsening over the past three weeks. He also has difficulty breathing when lying flat and has started using two to three extra pillows at night. Significant physical exam findings include bibasilar lung crackles, pitting ankle edem...
eligible ages (years): 18.0-999.0, Heart Failure years and older History of heart failure with an LVEF (less than OR equal to) < 0.35 for at least 6 months OR an LVEF < 0.45 with left ventricular internal end diastole (defined by a diameter of more than 2.9 cm per square meter of body surface area OR more than 6.5 cm ...
1
A 65 yo African-American male with shortness of breath related to exertion that has been worsening over the past three weeks. He also has difficulty breathing when lying flat and has started using two to three extra pillows at night. Significant physical exam findings include bibasilar lung crackles, pitting ankle edem...
eligible ages (years): 0.0-999.0, Congestive Heart Failure Heart Failure, Diastolic Heart Failure, Systolic Elderly Frail Guideline Adherence All patients who admitted to the participating centers due to acutly decompensated CHF defined by modified Framingham Patients who underwent heart failure treatment including in...
2
A 65 yo African-American male with shortness of breath related to exertion that has been worsening over the past three weeks. He also has difficulty breathing when lying flat and has started using two to three extra pillows at night. Significant physical exam findings include bibasilar lung crackles, pitting ankle edem...
eligible ages (years): 18.0-999.0, Heart Failure University of Michigan patients hospitalized for the treatment of heart failure, within the past 30 days Patients must be receiving an oral loop diuretic on their home regimen or have received intravenous loop diuretic during the index hospitalization at the time of enr...
1
A 65 yo African-American male with shortness of breath related to exertion that has been worsening over the past three weeks. He also has difficulty breathing when lying flat and has started using two to three extra pillows at night. Significant physical exam findings include bibasilar lung crackles, pitting ankle edem...
eligible ages (years): 18.0-999.0, Heart Failure Patients admitted with symptomatic heart failure, diagnosed within 2 years Diagnosis of congestive heart failure using the modified Framingham Simultaneous presence of at least 2 major or 1 major criterion in conjunction with 2 minor or a previous clear diagnosis of hea...
2
A 65 yo African-American male with shortness of breath related to exertion that has been worsening over the past three weeks. He also has difficulty breathing when lying flat and has started using two to three extra pillows at night. Significant physical exam findings include bibasilar lung crackles, pitting ankle edem...
eligible ages (years): 18.0-45.0, Preeclampsia Exposed cases African American women who are admitted to the obstetrical unit with a concern for severe preeclampsia. Patients must be preterm (23-36 6/7 weeks) with a live singleton gestation and at least 18 years old. Women will baseline chronic hypertension and women o...
0