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Types of font searches Talibah's picture I was wondering if there are any searches for font appearance that use exclusion or allow you to select multiple characteristics lets say I want to find all fonts with open 4's and has 7's with a strike through and I don't care if they are san-serf or serf but I also want to look for stencil fonts with double story E's. I would have to do separate searches. I'm kinda upset because instead of selecting for multiple characteristics I want in a font I'm selecting one and eliminating all others. Are there any better tools out there besides identifont? oldnick's picture Is there such a thing as a single-story e? Syndicate content Syndicate content
http://www.typophile.com/node/97326
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Subscribe Feedback English look up any word, like selfie: 1 definition by Joseph Ray Penis bear is a very insulting term used against old people. How ever if you know the old person, penis bear can be an endearing term. You can insult your grandparents or you can insult old people on the street. For example if you see an old person walking down the street you can say "Hey Penis Bear! shouldn't you be dead by now???" Or "Hey penis bear you are older than dirt"!!! By saying penis bear the elder understands that you are talking to them. However if you know the elder you can use it as an endearing term. For example you can say "Hey Penis Bear how you been?" or "I love you so much my shriveled up old penis bear" rss and gcal
http://www.urbandictionary.com/author.php?author=Joseph+Ray
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Subscribe Feedback English look up any word, like hipster: 1 definition by PimpDaddy Of Radders A term to describe how you punch an occupant in the mouth continiously until all of their teeth fall out onto the floor of the room where the Knockout Blow is situated. The Knockout Blow will either result in a knocked-out or minorly sedated occupant, therefore making it easier to get some much needed oral sex. I gave her a knockout blow tyson would be proud of. rss and gcal
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Subscribe Feedback English look up any word, like selfie: 1. Mark ass buster An individual who is always "borrowing" and gets crap from his friends. Also selling possesions just to eat dinner or play putt-putt. Man you are one Mark Ass Buster always seeling your old shoes for money to eat on. (E. M. B.) 2. Markassbuster Someone that one would consider a "homey", or friend. My bro Adrian is a real markassbuster rss and gcal
http://www.urbandictionary.com/define.php?term=Markassbuster
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Subscribe Feedback English look up any word, like thot: 29. teabag V. - To bring shame and humiliation on a helpless opponent by repeatedly placing ones scrotum, or nuts in their face or mouth. Also can refer to any act which is intended to mimic this repeated scrotal contact. Joe was crying tears of frustration and shame when I pistol whipped him and proceeded to teabag his fragged corpse until he respawned. 30. teabag v. to dip your nuts in someone's face or perferably mouth i teabagged reggie's face down in corpus by buiman May 10, 2005 add a video add an image 31. Teabag Dropping someones nuts into someones mouth. You just got teabagged. by Sias February 09, 2005 add a video add an image 32. tea bag latin: coleus gustatus from the book: Dirty Sanchez's Guide to Buck Nasty Sex 33. teabag the act of dangling, rubbing, sliding, and wiping one's testicles (and testicle sweat) over a victim's face whilst they are asleep, incapacitated, unconcious etc etc. usually preferred by performers of a heavily homosexual nature, but can also be used in a guy-on-girl situation with great success. GUY 1: "Dude, Sandy's just passed the fuck out!!!" GUY 2: "You GOTTA teabag that shit, man!!!" GUY 1: "She's gonna wake up to le' testicle' odor haha!" 34. teabag To crouch one someone's body after you kill them in a game (usually halo). To but your sack into someone's mouth. A porous pouch containing enough tea for one serving. That red team bastard teabagged me! Don't cry if you get neutered teabagging someone. Pass me the irish breakfast teabag please. 35. tea bag to dip ur balls in someones face when they are either dead or sleeping. the bungie dude got mad when i tea bagged him. rss and gcal
http://www.urbandictionary.com/define.php?term=Teabag&page=5
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Subscribe Feedback English look up any word, like poopsock: 1. gurbunkle The undesirable, awkward quasi-silence between two people in a car, elevator, or other isolated space caused when neither person knows what to say. Dude, I was just in the elevator with Jill, and it was filled with gurbunkle. It sucked. rss and gcal
http://www.urbandictionary.com/define.php?term=gurbunkle
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SGD Paper Help Xie Z, et al.  (2008) Atg8 Controls Phagophore Expansion during Autophagosome Formation. Mol Biol Cell 19(8):3290-8 Abstract: Monitoring Editor: Howard Riezman Autophagy is a potent intracellular degradation process with pivotal roles in health and disease. Atg8, a lipid conjugated ubiquitin-like protein, is required for the formation of autophagosomes, double-membrane vesicles responsible for the delivery of cytoplasmic material to lysosomes. How and when Atg8 functions in this process, however, is not clear. Here we show that Atg8 controls the expansion of the autophagosome precursor, the phagophore, and give the first real-time, observation-based temporal dissection of the autophagosome formation process. We demonstrate that the amount of Atg8 determines the size of autophagosomes. During autophagosome biogenesis, Atg8 forms an expanding structure and later dissociates from the site of vesicle formation. Based on the dynamics of Atg8, we present a multi-stage model of autophagosome formation. This model provides a foundation for future analyses of the functions and dynamics of known autophagy-related proteins and for screening new genes. Status: Published Type: Journal Article PubMed ID: 18508918 Topics addressed in this paper Number of different genes curated to this paper: 4 Topics Genes Additional Literature blue ball blue ball blue ball Cellular Location blue ball Function/Process blue ball Genetic Interactions blue ball blue ball blue ball blue ball Mutants/Phenotypes blue ball blue ball blue ball blue ball Primary Literature blue ball Strains/Constructs blue ball blue ball blue ball blue ball Author Searches 1. (1) Choose an author, 2. (2) Choose a search parameter, 3. (3) Click to implement
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Date/Time 19 Dec 2013 10:58:45pm Beg to differ. God is to be feared and there are many who believe but fear him. His vengeance is not too good apparently according to the bible. So all the believers should fear this bloke. He is a bloke isn't he? Animals have not got souls either is that right? Why are they created then, and why should they suffer, some in the most terrible ways? Don't get that. What proof have you that God exists? When you have not proof you resort to faith. Then you do not have to prove or learn or know anything, Fabulous copout. Why cannot non-believers read the bible? They usually know it better than the believers anyhow. If you read a book on serial killers it does not mean that you are one yourself? You do not make any sense.
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Forgot your password? Education Books Handhelds The Media Your Rights Online IT L.A. School District's 30,000 iPads May Come With Free Lock-In 232 Posted by timothy from the crony-capitalism-in-its-native-habitat dept. Comments Filter: • so 30000000 / 30000 = 1000$ per ipad? i take it they are ipad 1's pretty sad deal for the district. • Are you stupid? The $30 million is more than just for the iPads. It also encompasses staff hirings, training and support. • Not to mention the licensed content which is typically very expensive per seat. Think college book pricing. That's what schools pay already. Granted the books they buy have a multi year lifetime but this looks like a similar deal in the form of a subscription which will include updates. It's probably a better deal than we imagine. • by redback (15527) RTFA. $678 with a case and software. 16GB retina is 499, less with edu discount. what makes you think they would be getting a discontinued model? • by arbiter1 (1204146) Its a school, at best they are ipad 2's but best. they won't stick ipad 3 in students hands. • They might be 2s. They might be 3s. Or they might be minis. The article doesn't say, and there's no reason to conclude one way or the other from the given information. Apart from the included software, one reason they might cost more than retail is that Apple is covering them for broken, lost and stolen devices. Which presumably won't be insignificant for school kids. • Re:wait what? (Score:4, Interesting) by pushing-robot (1037830) on Saturday June 29, 2013 @08:24AM (#44141657) Read TFA. Of that $1000, $678 covers the iPad, the educational software, a case, a three year warranty, and free replacements from Apple for lost, stolen or broken units. The rest seems to be for setup, training and support. TCO is always going to be higher than the initial hardware cost, and this seems like a pretty good deal for what they're getting. Of course, in your infinite wisdom, I'm sure you'd just buy a shipping container full of $100 Chinese tablets, drop it on the school district's doorstep and say "You're all set!" That actually might not be a bad idea. Just give each kid a tablet, and let them do what they want. I bet the kids can figure out the machines faster than the school's tech support people. • It's important to keep in mind that Slashdot, and most of the sites Slashdotters visit, tend to be echo chambers for technology geeks. Outside this bubble, however, most people (and even most kids) don't consider "self-taught computer genius" to be their goal in life. In other news: Farming message board posters outraged at cost of school lunches, think students should be given bag of seeds, hoe. • by horeton (82590) * on Saturday June 29, 2013 @08:06AM (#44141541) Homepage My son is in a year round STEM school in NC and their school uses a system based on android called Amplify http://www.amplify.com/ [amplify.com]. It isn't just an app it is a modified android tablet that allows students to participate as a collective in the individual classroom. Students can use the table to raise their hand, ask question and participate in classwork. Teachers use it to teach their curriculum and after a lesson can deploy a quick quiz so the teacher knows who understood the lesson and who may need additional help. Teachers can see what each student is doing on their tablet at any time with the master teacher's tablet. Each individual student has their own tablet and the tablets are locked down, always on with att 4G when off campus and students take the tablets home to do their homework on them. Their main responsibility is charging the tablet every night. It has been great over the last school year watching my son enjoy his curriculum in new ways using his tablet and the best part is really how well the tablet fits into the classroom and is replacing the tradition text book. The program was supposed to be only a 1 year test of the product but the school has asked to allow the 6th grade students to continue to use their tablets in 7th grade. Kudos to Amplify I hope all schools in this country will stop wasting money on promises and use something that I personally have already watched prove itself as a fantastic learning product for my 7th grader. • Fellow North Carolinian and parent here. Would you mind giving me the name of the school? I'd like to learn more about it. No wonder obesity is so bad in this country. • by Charliemopps (1157495) on Saturday June 29, 2013 @08:19AM (#44141627) ...and this is why our schools are failing. A local school was complaining that they'd have to lay off a bunch of teachers recently. Come to find out they'd also recently installed a $3000 digital whiteboard into every classroom. What the fuck is wrong with our schools? You're think teachers could do basic math. I understand that the boards can make the teacher more productive... but those boards are going to fail. Chalkboards and whiteboards don't. For what they spent on those boards they could have kept 4 or 5 teachers on staff. How many teachers could the school district hire for $30 million? I could understand if our school systems were flush with cash but they're not. Once class sizes are bellow 20 students and teachers stop protesting about their raises and benefits, maybe then we can think about giving the kids toys to play with? • Re: (Score:2, Insightful) by tlambert (566799) ...and this is why our schools are failing. They always complain about that. Then they send out pink slips. Then they don't lay anyone off. It's a scam by the teachers union, where your career path exits teaching and moves into administration so that you can make 2-3x the money while parents are forced to buy paper and pencils for their students. BTW, the student/teacher ratio is about 2X larger in Utah, and their SAT scores are in the top 10 of the nation, rather than in the bottom 10, as in California. So throwing money or teachers at it doesn't • Re:sad (Score:4, Funny) by AthanasiusKircher (1333179) on Saturday June 29, 2013 @08:43AM (#44141751) So what you're saying is... we need more Mormons in our educational system?? • by rahvin112 (446269) My experience is Mormon parents are much more involved in their kids education than the general populace, and that's the difference. Average class sizes are around 32 kids per teacher. The teachers are some of the lowest paid in the nation and even things like textbooks go years without being updated. Education isn't something you can throw money at to fix, it's a parental responsibility issue. • That's a very silly claim. Yes, there are too many administrators. But attrition in teacher ranks is not being caused by teachers moving into administration. If there is a reduction in teacher numbers in a district, it's due to budget cuts. More typically teacher numbers are staying the same or increasing, but not at a rate that keeps up with increasing enrollments. I say this someone who teaches and who therefore really hates the increases in administrative overhead. • Wait. What? Cite source? According to this: http://www.statisticbrain.com/sat-score-statistics/ [statisticbrain.com] California is 34th, and Utah is 20th. Two things. First, the difference between California and Utah is only 146 points. Second, California is a pretty big state with a lot of socioeconomic disparity. More so than Utah. • Re: sad (Score:4, Informative) by tlambert (566799) on Saturday June 29, 2013 @12:49PM (#44143011) Wait. What? Cite source? http://law2.umkc.edu/faculty/projects/ftrials/states/uschartsat.html [umkc.edu] http://www.publicagendaarchives.org/charts/state-state-sat-and-act-scores [publicagendaarchives.org] ...But even using your source, change it to "Utah is in the top 20, California is in the bottom 20". And I really don't care about cultural bias because college admissions boards don't really care about cultural bias, they care about SAT scores. And to get a reasonable picture, you should compare spending per capita by state: http://www.usgovernmentspending.com/compare_state_spending_2013b20s [usgovernmentspending.com] California spends more than 7 times what Utah spends, and gets a poorer result. But if you don't like Utah because you don't like mormons, pick another state higher up in the second table, and compare it to California; California is only going to look worse. • by melikamp (631205) And while we are at it, may be we can give our kids cheaper toys, running a full-featured free software OS and free educational software, which the kids can study. Using non-free software to educate (really, to program) the students is a clear sign of corruption. I suspect a traditional kind of corruption, when inferior, overpriced products are adapted in exchange for some kind of kickback. And for sure, there is a corruption of the pedagogical ideal here. What can a black box really teach a student? "Never • You realize the textbooks schools buy are probably more expensive than the iPads, right? And quicker to go out of date? This actually seems like a money saver to me. • Is the famous USA educational system becoming the pinnacle of consumerism? Where pupils need only to consume hi-calorie concentrate food canned in hi-tech tablets and evaluated only by pressing their fat fingers on multiple choice questions check-boxes? "Question 1: The rectangular machine you have in your hand at this very moment and reading this question on is: a) a tablet b) a computer c) a calculator d) a PC e) an iPad" • PEARSON (Score:4, Insightful) by supercrisp (936036) on Saturday June 29, 2013 @09:09AM (#44141883) I'm not seeing posts here addressing the more serious issue, which is the lock-in to Pearson. I know people who work at Pearson, and they do have an intentional policy of moving into schools, taking over curricula, evaluation, and eventually eliminating teacher jobs. I think that it's good to have plenty of teachers, fewer students per teacher, and I'm skeptical about the value of the new shiny, whether it's a gadget or some theory of fixing everything cheaply, but--by far--the more worrying concern is allowing a single corporation have such a large sway over public education. Especially as, in my opinion, Pearson provides some of the shittier textbooks out there. And that's saying something, given the general shittiness of textbooks. • by jbolden (176878) The market for textbooks is profitable and competitive. School districts individually have the ability to purchase texts. There are just under 100k school districts. By going to electronic texts all sorts of less expensive texts become economically viable. I'm having a hard time seeing how exactly is this a threat that Pearson establishes a long run monopoly without them hugely outperforming competitors. I think most textbooks are terrible until college. But that's the school district's fault not Pearson' • How can adopting a particular curriculum lock in students for "generations"? School districts / states can, and do, make curriculum changes All. The. Time. • by Dcnjoe60 (682885) on Saturday June 29, 2013 @09:34AM (#44142009) Of course, what is missing and hard to find about the Common Core Standards is they were started by the government (state governors association, I believe) to standardize curriculums and teaching methods accross the states with one of their key reasons being to hold down education costs. That has since been removed from the website, but the CCS was not about improving educational standards but cost containment. How will they do that? Pay teachers less and pay Pearsons more. You want to improve education in America? Find out how the 1% educate their kids. It won't be cheap, but you do get what you pay for. • by UBfusion (1303959) If it was possible to "standardize curricula" based on "state of the art" educational principles in order to minimize "costs", it would have already have been done 50 years ago, not only across US states, but across countries and continents too. If you come to think about it, the Sciences (Physics, Astronomy, Chemistry, Biology, Maths, Geology, etc) are universal. The only differentiating subjects are language and to an extent, history. So the globalization, standardization and "canning" of knowledge to teac • by The Second Horseman (121958) on Saturday June 29, 2013 @09:35AM (#44142021) You know what's worse than government? Government contractors and suppliers. • by jbolden (176878) Private profits from the public taxpayer's dime, Yeah. That's what government spending usually looks like. Our government buys services from the same market consumers and business do which is mostly private business. The alternative would be the government runs most industry almost completely communist state. • That's a refreshing $1,000 a pop. Wasn't "high volume purchase" meant to work the other way, originally? Did I just miss another great innovation by Pearson and Apple, along the lines of "The more you buy, the higher the per-item price"? Not to mention the fact that iPads are, by design, nearly non-repairable. What a bad idea to give such an example of non-sustainability to young people these days. Not to mention that an all purpose computing platform, like a netbook, with a choice of OSes and application softwa • software and books cost add up as well. • by BonThomme (239873) if it's Apple, it's patented... A method and system whereby purchasing in larger quantities increases your unit cost... • That's a refreshing $1,000 a pop. They don't pay $1,000 for each iPad. They pay $678 for an iPad with five your warranty AND insurance, with tons of educational software. And then there is other cost related to this purchases, like training and so on, probably charging stations, something to look the iPads away when not used and so on. TCO is more than purchase price. • netbooks are $200 and less in quantity. they have keyboards. they are not owned and operated by one corporation who thrives on restricting your rights. anything apple for school is just plain WRONG. we've seen enough about apple corp. why would we think its ok to start (continue?) the brainwashing of kids, just because the dumb adults love Teh Shiney(tm) ? a pc (even with MS sw installed) has much more freedom than anything apple puts out. if you choose to waste your money on apple products, that's up to y • and it's incredibly frustrating. I'm a bright guy and I can help her with her homework, but I don't remember everything from high school physics or algebra/trig. And with humanities and the Arts there's often a 'right' answer from the teaching materials. I used to wonder why this stuff wasn't online until I saw the profits those textbook companies make. Stupid capitalism. • Corporate greed and corruption at it's finest, and all done in the name of "for the education of our kids". Shame on Apple. Shame on Pearson. And shame on the people who got paid off for this at LA Unified. • by UBfusion (1303959) It's not a shame to be greedy and to want to make money. That's our religion after all (capitalism). It's a shame, maybe even a crime, to do it by exploiting children's thirst for knowledge. • I think Pearson hopes schools do not adopt texts which are not available on the iPad. LAUSD will be paying for new editions of the same virtual books in perpetuity. This is corporate welfare at its finest. • There are $100 tablets that kick the crap out of an iPad on portability and compatibility and battery life. There are even more $200 ones. The Samsung Tab 2, Avatar's about to be released new tablets, most of the AGPTek ones, some iView models all crush the ipad on useability and features vs price. I can't see why a school district would waste money on such a locked down, overpriced tablet like an iPad. • by jbolden (176878) There are no $100 laptops that are even close. I doubt even granting a way slower system with a much worse screen and camera you can get both portability (weight) and battery life higher at the same screen size for $100. Let's take your iView 7" model Definitely cheap. We'll compare to the iPad mini 512M ram vs. 1g 4g storage vs 16-64g 800x480 vs. 1024x768 Back 2MP webcam and front 0.3MP webcam vs 5MP/1.2MP with a much better lens 2.1 lbs vs. .68 lbs (so much for better portability) Those two products are just • The iPad is for the wow effect for the kids to want to learn about common core. A propoganda program. • ... my wife is a teacher and her high school decided all teachers must have and use iPads. She teaches horticulture and the apps in the Apple store are all for preschoolers, maybe grade 3 max. She found one or two BBC interactive documentaries with David Attenborough but that's it. Everything else is babysitting software. Almost (not total) waste of money, and they're laying off teachers because they don't have enough funds. Training for the iPads? Two two-hour sessions for the staff. That's it. I second the t
http://yro.slashdot.org/story/13/06/28/2351233/la-school-districts-30000-ipads-may-come-with-free-lock-in?sbsrc=md
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FBC 41 English 41 Set Clip Length: of intellectual inp integrity. >> that is leadership, people want romney to go into the first presidential debate who put romney away in the race in florida where he bested annuity begin newnewtgingrich. who is the best debater. it is relevant. romney does best when he is the under dog. on the ropes, this lead by 14 points in middle class, most americans think of themselves in middle class, and most are struggling is a political number, politico buried that lead, they led with romney pulling away. lou: i forgot the question. >> it depends on where those middle class people are, there are three places this matters, ohio, virginia and florida. lou: president obama still maintains a lead. >> he leads in those places, and this is hilarious because senate race in virginia appears to be a lock, and obama is running away with the state, it is a bad campaign they need too take stronger issues. putting president on notice. on real issues. lou: i am hearing you say, what kelly ann would not, governor romney is doing the right thing. >> americans don't give the presidency up lightly to anyone, they don't ta think that mitt romney is in a position to win this presidential race. i think it is very important that he stop acting like a candidate and start acting like the president of the united states. what i would have had him do today is be meeting with these four leaders as the president refused to do and give that differentiation between the president of the united states sitting there on a talk show talking about being eye candy and having mitt romney meeting with leaders to try and solve these problems. that is what will be hit -- see him do. lou: and yet, and yet president obama, despite brushing aside the prime minister, despite just simply refusing to meet with any number of the leaders who one would have believed, as we pointed out, are from that statement by the candid obama some five years ago, really. it just makes no sense, what is happening here that suddenly the campaign takes priority over the business of state. >> well -- lou: and there is no comment in the mainstream media. >> well, the mainstream media has totally brushed anything this president has done a side of what , money that was going to, or pledged to mitt romney's presidential campaign being diverted to house and senate seats. you have key republican donors, many in the new york area, that is one of the good things about covering wall street, i know a lot of the big money twice here. that money, from what i understand is starting to be diverted to hoist and senate races. that is not good news for mitt romney. could this change? i could tell you this. i talked to people inside the romney campaign. they confirmed the trend. they confirmed the trend is beginning. they believe it is reversible. one good strong debate performance, coupled with the facts polls showing president obama ahead nationally and key battleground states. one good debate performance can reverse this and bring it back to the campaign trail which is needed. if you look at overall numbers, president obama basically out raised mitt romney two to one. in terms of overall numbers. mitt romney raised a lot of numbers. president obama used a lot of his money early on. so the edge has been narrowed. but clearly they need money for of governor romney. >> we know all the time the presidential candidate has to be smart enough not to get himself in the holes and he has not passed that particular test. it's not enough, should not be enough to shift the whole world media, but if it does, it does. he's got to be beyond it, that's his challenge and he's got to make a credible case. >> so much of what's going on with the white house and the administration, they've misdiagnosed the economy, they've misdiagnosed the problems, you know, we had, you know, a summer of recovery, escape velocity language out of the who white house and 2010. and even the federal reserve saying we're more focused on inflation in in 2010 than growth-- is the american media more focused on economic justice versus economic growth? >> to a degree i agree. we need a recovery to recover from this recovery. and it's badly structured, badly thought through and frankly the possibility of doing something early enough is behind us. so everybody is paying the price in terms of the national economy. but the reflection of that is, 23, 24 million people who were invitation to presidential candidate romney. i would like to see every level of government. david: alexis, i have to press my point with you. how do you monotize getting the president on? for example, if you're a book writer, if you have the president holding your book saying that is a good book you can capitalize on that. how do you that from a website perspective. >> i may not be that good of an entrepreneur to figure that out. it obviously legitimatized red did and put it on. that monetizaton will come but i expect any photos of the president on reddit. liz: you could have gotten a ton of extra people and if houston rockets general manager is doing it may become a great tool for people to self-promote. are you selling advertising? how are you making money on the site? >> at the moment reddit sells ad. like a lot of social media sites advertising is way we make our money. what is interesting bit the ads are sort of embedded in the content. the way they can vote on links and vote on ads. same way they can comment on links an comment on ads. advertisers build discussions build dialogues with , a huge miracle. today from apple. details. and is mitt romney ready for next week's presidential debate? the first one. a new memo shows there may be some concerns. details next. ♪ lori: president obama getting some debate press today before heading to a flight of fund-raisers. the president and mr. romney said to face often less than one week for the first presidential debate. both campaigns are downplaying the candid wiping of their opponents. how will these low expectations play out? with more on this, joined by ed rollins, republican strategist top boxes contributor. likewise, doing great, especially looking forward to this conversation. what is the strategy? >> you cannot play down the debate. the biggest thing left in his campaign. if you don't do well it does not matter whether you said you're not going to do well. you discord against. traditionally presidents don't do as well in debates. nobody basically stands up and makes points back-and-forth. sometimes they're hard to get going. this president is a good debater. my sense is he will be on his best. romney obviously became a -raisers. the president and mr. romney said to face often less than one week for the first presidential debate. both campaigns are downplaying the candid wiping of their opponents. how will these low expectations play out? with more on this, joined by ed rollins, republican strategist top boxes contributor. likewise, doing great, especially looking forward to this conversation. what is the strategy? >> you cannot play down the debate. the biggest thing left in his campaign. if you don't do well it does not matter whether you said you're not going to do well. you discord against. traditionally presidents don't do as well in debates. nobody basically stands up and makes points back-and-forth. sometimes they're hard to get going. this president is a good debater. my sense is he will be on his best. romney obviously became a very good debater. style versus substance. charismatic, a great debater. romney, livermore. also very strong in a primary debate, as you just alluded to, especially against gingrich. >> i'm sure fully ready to go push and shove. i hope the talks more about what he will do as preside : thank you so much. still to come, a huge miracle. today from apple. details. and is mitt romney ready for next week's presidential debate? the first one. a new memo shows there may be some concerns. details next. we asked over 3,000 doctors to review 5-hour energy and what they said is amazing. over 73 percent who reviewed 5-hour energy said they would recommend a low calorie energy supplement to their healthy patients who use energy supplements. seventy-three percent. 5-hour energy has four calories and it's used over nine million times a week. is 5-hour energy right for you? ask your doctor. we already asked 3,000. not quite knowing what the next phase was going to be, you know, because you been, you know, this is what you had been doing. you know, working, working, working, working, working, working. and now you're talking about, well you know, i won't be, and i get the chance to spend more time with my wife and my kids. it's my world. that's my world. ♪ ♪ lori: president obama getting some debate press today before heading to a flight of fund-raisers. the president and mr. rom . david: at the very heart of republican presidential nominee mitt romney's energy plan is a decades old debate over exactly who should be controlling drilling and mining, the states or the feds? fox news's alicia acuna is in denver with the details. hi alicia? >> hi, david. part of governor romney's energy plan includes removing federal controls over energy production on public land and handing it over to individual states. as you can imagine this is a pretty sensitive issue this western part of the country in particular because unlike places like oil-rich north dakota where private business and the state has a lot of control, the american west is home to most of the nation's public lands. right now for energy exploration and production to happen on federal land companies go through an extensive permitting process that could take months to years the romney plan changes timeline, speeds it up by giving states more power to work with companies and regulators through the process and therefore the candidate says increase america's energy production and security, something industry argues co , the vice presidential candidate, has an even better plan than romney has, and that's junk the code, have two rates after exemptions, 10% above $100,000, 25%. that would get the economy moving. >> what mike was talking about, all of these tax cuts just add to the tax code, they don't make it simpler or smaller. >> i can get behind a simpler tax code, but i'm still suffering from the ripple in the force i felt when david asman told me i was right. i'm going to lose my liberal union card. steve pointed he likes the vice president's candidate program the president's candidate. all of you republicans seem to bant paul ryawant paul ryan for, but he's not. >> i heard you say no about the idea of tax simplification. why is that not a good thing? >> we're all basing this argument predicated on lower tax rates are going to stimulate things. companies are not using the industrial capacity they have now. they laid off workers because there's no demand. cut their taxes, it doesn't mean they're going to build another factory if people aren't buying their goods. it's lunacy to think this would fix the donors looking to hedge their bets away from republican presidential hopeful mitt romney to help republicans in key house and senate races. charlie gasparino has the exclusive details on the latest obstacle, it seems, faced by the romney campaign. >> reporter: i don't think you can sort of term this as a mass exodus yet, but what we're hearing from people inside the campaign, people that raised money from the campaign is this, that in the next couple days, maybe last week or so as those negative, as those poll numbers have gotten worse for mitt romney particularly in the battleground states, what you see is the big money contributors, and particularly i hear this is happening in new york, i also hear it's broader based geographically. they're starting to hedge their bets. a lot of people thought they'd start beginning to president obama. i hear they're not doing that, but they are diverting money that was promised to mitt romney and diverting it to these house and senate races where they think they can help republicans keep the house and maybe pick up seats in the senate, maybe t to go back to the presidential election. mitt romney in the famous video that leaked out it said oh boy if i'm up in the polls -- he gave the impression of donors down in florida, if i'm leading in the fall in the polls, i think the market will reflect that and you could see a rally. you could say he is not leading in the polls and the market is still doing pretty well. is that because people are optimistic about obama reelection or is that because we overblow this and there's not that much relationship between the two? >> i think the market is going up because we won't go into a secondary recession. i don't think china falls apart. and you have got this performance anxiety. you know, 11% of professional money managers are outperforming the s&p. the rest of them have got a lot of catch-up to play between now and year end. connell: that's a good point too. yes they do. we're up 53 today by the way. jeff, always good to see you. thanks for coming on. >> pleasure. dagen: toys "r" us looking to make a big hiring push for the coming holiday season. the toy retailer says it will hire 45,000 s in 2002 over a billion watched worldwide. first of three presidential debates. romney said it is not just one but many could posit of last five weeks remaining before now and the election. melissa: campaign carl cameron. you are the best. thank you so much. tomorrow night be sure to tune into neil can view toes -- cavuto's coverage of the presidential debate 8:00 eastern on fox business. coming up tonight on "money", gary johnson libertarian nominee for president of the united states. he joins me ahead of the debates in denver. that is 5:00 p.m. eastern here on fox business. >>> the clock is ticking to the fiscal cliff and the allic cuts it will bring but lockheed martin is telling fox business they have been assured by the department of defense that they will not be subject to any major cuts. what's going on? tracy byrnes and ashley webster have the story next on fox business. before copd... i took my son fishing every year. we had a great spot, not easy to find, but worth it. but with copd making it hard to breathe, i thought those days might be over. so my doctor prescribed symbicort. presidential debate. the we've shown you the headlines. the media has not stopped piling on romney. and we'll ask pat caddell, he says they're ruining the country. the democrat we had on yesterday said this. >> generally what happens in the first debate is the challenger succeeds. 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[ male announcer ] yes, it is, business pro. yes, it is. go national. go like a pro. >> and norquist threw and presidential nominee mitt romney should be doing talking about the plan that decreases the overall tax burden for americans in general. it's not just about the small minority or majority of the people who aren't paying some income tax, they're talking about the problems they have right now that doesn't have people concerned about their tax income liability because they don't have one. remember, too, this is just on the federal income tax side. we do have a lot of the people paying payroll taxes and social security taxes, and it's. an uphill struggle. it's a tippingpoint we've crossed the tippingpoint and it will be an uphill struggle to send that tax burden to everybody. >> i agree with you, but it's possible. stuart: you got the last word. thanks indeed. see you. could smith electric be the new solyndra? government-backed green energy company, smith electric that the president visited is now on the verge of failure. we'll talk to the chief executive officer. this is what mr. obama said when he visited the country's factory. >> one of those was to provide critical funding to promising innovat the consequences are so awful they will work it out. figure out a way. be hopeful. president obama and mitt romney make history in their first presidential debate tomorrow night. fox business will be there and neil cavuto hosts special coverage at 8:00 eastern time tomorrow. tracy: is your boss spying on your cell phone. an interview you need to hear before agreeing to get your company's e-mail on your smart phone. dennis: why all the recent hiring plans for holiday sales jobs could be a bad sign for the economy. tracy: con 70 points possible to make money with charles payne. should hold the has been moving. you like it before. charles: getting hammered. we new stock was going to get hammered because of the annual report and hammers something so we knew one to stocks would be hammered. i had it on the show at 295. stock was at 350. nineteen% move in two weeks. i gave it to my paying subscribers two weeks after i had it on his show. we took profits on it already. 19% is a lot. let's go to david einhorn. i am wondering if he is resting on his laurels. that started to turn back of. if he likes genera . >> thank you. melissa: speaking of the campaign, republican vice-presidential nominee paul ryan is in ohio today to push the romney plan for a stronger middle class. in a fox business exclusive our very own rich edson sat down with ryan in the important swing state. >> melissa, when you talk about ohio, the other swing states like florida, the problem for the ryan-romney campaign they're beginning to see a little bit of an opening for president obama. he is picking up steam in some of the polls here. we asked congressman ryan what they could do to try to address that. he is basically saying don't worry about it. if we highlight enough how bad the economy is, when election day comes around they will win this thing. we also spoke about the comments that governor romney had made a couple of months ago talking about those americans, nearly half of them pay no federal income taxes. >> because of the stagnant obama economy, more able-bodied people are dependent upon the government because they have no opportunities in this economy. what mitt and i are trying to do, say, here are the ideas to get disadvantages of senator mccain, and governor romney is still running against george w. bush with economic policies. >> yes, but that was -- that's been true in the past, and many presidential changes -- for example, think about president reagan, he was running against the catastrophic effects of nixon's wage on price controls lasting up to 1980 and carter. the "new york times," i have to remind you, the "new york times" on the eve of the election between reagan and carter had it too close to call. lou: the third debate? >> that is right. lou: i know it's right. up next, governor romney trailing in the polls, but does history show come from behind wins are possible? as we disused, there -- discussed, there is history here. we'll have the report. are taxpayer dollars -- they call it art, but looks like obscenity to me, but there we are. we'll look at the ways in which the obama administration expresses religious sensitivity and tolerance and other ways in which had does not seem to give much of a damn. we'll talk about catth catholic league president, bill don hue and karen handle here in j romney is being so specific as he is campaigning right now because you realize votes are being cast. >> analysts say they believe about 35% of this year's presidential ballots will be cast before election day. lou: shannon, an impressive number indeed. we'll have more on the impact of early voting in the election. we'll take that up with "the a-team" coming up here next. >>> protests in greece, outrage in spain as many european countries are forced to slipping their massive government spending. are we seeing the end of the euro or the other side of the fiscal cliff? former reagan economic advisor, economist arthur laffer joins us. >>> the republicans shun congressman todd akin's campaign in missouri. >> these were reprehensible and deplorable comments and there is no way he can recover in my opinion. so our group decided if he remains the nominee there is no reason to throw good money after bad by, by trying to win this seat. lou: now surprising facing rallying around him as republicans look to take over the senate. president obama with the time to be on day time television but not of the presidential race, i think i can say this, is what we're calling income envy. according to a new poll, that issue may be swaying in mitt romney's favor, how about that? a politico george washington survey, of voters, gives romney the edge by a wide margin. leads president obama 55-41. that is 14 points, interesting. i don't know how they define middle class, but that's the result of the poll. and coming up in the ten o'clock hour, two big names in the republican party, rnc chairman, and karl rove coming up next hour. and i used to live in california, a beautiful state that has a great deal to offer, got it. it's now a horrible place to do business, job killing environmental laws, job killing regulations and as a result, people are leaving in droves. that story is our new at 10 story, the max exodus from the formerly golden state. and then our guy in california will join us about that exodus from california. let's go nicole, in the past we put blackberry maker rim on death watch. cue the-- ♪ >> nicole, is it right to put them on death watch? >> i don't know what to tell you. be very voters may be down a point or two. cheryl: we're going to see the first presidential debate a week away, scott. i'm curious, because you're sampling so many different folks on so many different issues, what do you think mitt romney needs to come out with swinging as a topic, as a headline in that debate to get the polls back in his favor? >> he needs to come out with something that shows he gets i. i -- it. ronald reagan was good at that, newt gingrich was good at turning the tables on questions this primary season. mitt romney would like to have some of that. that's not really his strong suit. the second best thing for mitt romney would be a major gaffe by president obama, so perhaps mitt romney could goad the president a little bit into some comments about small business other thans or something else. owners or something else. because the race is close enough that any change could have an impact. but, cheryl, historically debates have not moved the numbers all that much. four years ago when barack obama debated john mccain, mccain was down by five points when he went into his debate, . i think most people don't get it yet. they don't understand the romney prescription. he has time. i want to emphasize, the race is not over yet. plenty of money, two more unemployment reports to come three presidential debates. he has time, but he has to explain clearly why his plan is better. stuart: i've got one more thing i wish you could explain for me again. again in a poll in ohio out this morning, it gives president obama a 25 point lead amongst women. can you explain it? >> well, you know, object on a lot of social issues, i don't think that ryan helped. ryan and todd akin in missouri supported abortion legislation that's pretty harsh and the gend gender gap widened after ryan was put on the ticket. a huge gams. that's another one of these polls, like the florida poll, i just don't quite believe the numbers. >> we agree, i thought we would have a violent disagreement, greg. >> go figure. stuart: i don't get it. hey, greg, always a pleasure, i'm sure many times in the next 41, 43 days, what is it. >> looking forward to it. stuart: see you later. check the price of oil, please of the presidential election, and now a top obama campaign advisor says women haven't been paying attention the past four years. could that cost the president votes? and how the romney camp can make up a big gap among women voters. next. so, we all set? i've got two tickets to paradise! pack your bags, we'll leave tonight. uhh, it's next month, actually... eddie continues singing: to tickets to... paradiiiiiise! no four. remember? whoooa whooaa whooo! you know ronny, folks who save hundreds of dollars by switching to geico sure are happy. and how happy are they jimmy? happier than eddie money running a travel agency. get happy. get geico. fifteen minutes could save you fifteen percent or more. can youlyric can.aid do this? lyric can. lyric can. lyric by phonak is the world's only 24/7, 100% invisible hearing device. it's tiny. but lyric's not just about what you can't see. it's about what it can do. lyric can be worn 24/7 for up to four months, without battery changes. incredibly easy to live with, lyric can be worn showering, sleeping and exercising. in fact, you might forget it's there at all. cal congress and presidential candidates to not worry about the deficit because you can finance another trillion dollars for free. i know that 70 basis points is a rounding error. to them, it is free money. if romney really wanted to attack the problems of this country, he was a solvency is our number one problem and we will go after this budget and get it under control. number two, the economy and capitalism is being ruined by the fed and i will clean house and they want, job one, bernanke goes. he needs to say that. dagen: if there is always the debate. thank you very much, david. connell: bernanke. let's talk a little bit about him right now. dagen: bring it. connell: he will be there at the indiana economic club today making his first remarks in public. dagen: rich edson is standing by with more. >> a very fine city. bernanke speaks about an hour and a half from right now. five questions about the federal reserve and monetary policy and, boy, have there been changes to monetary policy. there is already signs that qe3 is working. however, also, to peter barnes, this man disagreed. >> Excerpts 0 to 40 of about 41 results. 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x lipper CNN 16 English 87 Set Clip Length: by government through fiscal policy was the real blow-up risk. so if you think of a couple places in the world that we were the most afraid of like europe, i think the actions of the ecb to at least defer the problems with the sovereigns and the bank issues in europe, if they use this time to fix the problems, we'll look back and think it's a good thing. if they deferred them, made them worse in the long term, we won't feel that way. i think something similar has happened in the united states whereby a lot of liquidity has been provided by the central bank. >> andrew, you have operations throughout all of the world. what's your sense of growth? there are troubling reports about growth slowing down which so far have been a very powerful lifeline for global growth as united states and europe weakened, particularly china where you do a lot of business. >> i don't think we're going have an '08/'09 scenario out there for the reasons lloyd was addressed. i do think the world since '08/'09 to now has not gotten to normal. of course, the obvious, which is consumption in the u.s., is not where it was. in advance will be three on the economy and one each on health care, the role of government and governing. with an emphasis throughout on differences, specifics and choices. both candidates will also have two minute closing statements. the audience here in the hall has promised to remain slinlt. no cheers, applause, boos, hisss among other noisy distracting things so we may all concentrate on what the candidates have to say. there is a noise exception right now, though, as we welcome president obama. and governor romney. [ applause ] >> jim. >> gentlemen, welcome to you both. let's start with the economy. segment one, and let's begin with jobs. what are the major differences between the two of you about how you would go about creating new jobs? you have two minutes. each of you have two minutes to start. a coin toss determined, mr. president, you go first. >> thank you very much, jim, for this opportunity. i want to thank governor romney and the university of denver for your hospitality. there are a lot of points i want to make tonight, but the most important one is, 20 years ago i became government. who believe that they are victims, who believe the government has a responsibility to care for them. who believe they're entitled to health care, to food, to housing, you name i. that's an entitlement and the government should give it to them. and they will vote for this president no matter what. and i mean the president starts off with 48, 49, he starts off with a huge number. 47% of americans pay no income taxes. so our message of low taxes doesn't connect. he'll be out there talking about tax cuts for the rich. i mean that's what they sell every four years. my job is not to worry about those people. i'll never convince them they should take personal responsibility and care for their lives. >>> a new poll finds 45% of registered voters feel more negative about mitt romney after that 47% comment. just 23% feel more positive about him. 24% said the comment did not make much difference. and because of what they've read, seen or heard about mitt romney over the last few weeks, 51% now have a less favorable impression of mitt romney. 28% have a more favorable impression of rom , the federal government for the $10 a shake jpmorgan got not only bear stearns' assets but liabilities, including, authorities say responsibility four some of the most egregious conduct in the financial crisis you churning out residential mortgages by the thousands, bundling them into what the firm told investors were quality securities, knowing all along many of the mortgages were duds a systemic fraud on thousands of investors, the lawsuit says, deceiving them about the fundamentally defective character of the mortgages and went housing bubble burst, those investors are suffered monumental loss, jpmorgan plans to contest the suit and disappointed with the ag for bringing the case and says it is the first product of a presidential working group on american securities fraud formed in january. today in washington, officials signal it had won't be the last case. sue? >> scott, stay with me. we are going to talk about this joining us first on cnbc to discuss the lawsuit is new york attorney general eric schneiderman. welcome, sir, pleasure to have you back with us on "power lunch." >> tha two plans. and by the way, if the government can be as efficient as the private sector and offer premiums that are as low as the private sector, people will be happy to get traditional medicare, or they'll be able to get a private plan. i know my own view is, i'd rather have a private plan. i'd just as soon not having the government telling me what kind of health care i get. i'd rather having a insurance company, if i don't like them, i can get rid of them and get a different insurance company. but people like to make their own choice. and the other thing we have to do for medicare, we have to have the benefits high for those who are low-income, but for high-income people, we're going to have to lower some of the benefits. we have to make sure this plan is there for the long-term. that's the plan i put forward. and by the way, the idea came not even from paul ryan or senator wyden, but it came from bill clinton's chief of staff. this is an idea that's been around a long time. which is saying, hey, let's not see if we can get competition into the medicare world, so that people can report from the government. today thursday's weekly jobless claims report. that hits the wires at 8:30. in the meantime, what's been happening in europe is that things have barely bunched there again and they seem to be taking their cues from us.dnched there aganfroms.gnched there agand they seem to be taking their cues from us.ched there again and they seem to be taking their cues from us.hed te again and they seem to be taking their cues from us.ed there again and they seem to be taking their cues from us. dow, nasdaq, s&p all closing slightly higher yesterday. in asia, a long week without chinese trading, but in japan, the nikkei was up by about 77 points. and in bombay, sensex up by 188 points. oil prices actually energy stocks yesterday were lagging as we saw big tumble in crude oil prices. back up by about 6 # ce4 cents, those are levels we haven't seen in quite some tile. ten year note, yielding 1.63%. so that's a slightly higher yield than yesterday. the dollar interesting story, too. you'll see that it is down against the euro. but still 1.2951. so we've been right around 1 the government out of the housing market. that's all ahead on the "closing bell." if we want to improve our schools... ...what should we invest in? maybe new buildings? what about updated equipment? they can help, but recent research shows... ...nothing transforms schools like investing in advanced teacher education. let's build a strong foundation. let's invest in our teachers so they can inspire our students. let's solve this. >>> all right. we got more situations developing. yum brands out with earnings. to jane wells. she's got the latest on yum brands. over to you. >> yeah, maria. you had it right going into the break. they did beat the street on the bottom line, coming in at 99 cents, excludeing special items. that's up 19% from a year ago. the top line came in a little light. the street was looking for $3.65 billion. the real story is what's happening in china. they reported an operating loss in china last quarter. this time, as promised, they have returned to double-digit profit growth with the china system sales increasing 22%. same store sales increasing 6%. now this is a slowdown . the president supports the position on the creation of jobs and the government can't do everything but it has a responsibility. we have lost public sector jobs and we have laid off a lot of cops, firefighters and teachers. that is not the way to get the economy humming again. >> governor gilmorgilmore. aka governor romney, what is your solution? >> the economy is another serious problem. that is another way of talking about the plight of real people out there. after four years of stewardship, i can say that we are not moving in the right direction. we are picking up 100,000 jobs a month. you have to have 180,000 just to keep pace. we are not in a recovery. growth is under 2% while it has been 2.2. that is why we are sitting around after all these years. we have a specific plan. that plan are tax incentives in order to build up this economy and great growth. you can't do anything in this country until you get growth going again. until there are plans in place. talking about a tax reduction so that they can spend more money. so that they are xare competiti with over seas people. >> you heard go businesses based on the government. >> fewer than 500 employees. >> exactly. you can fit all the ceos of firms in madison square garden. the rest of the businesses in the population of south carolina. you are talking roughly 18,000 people who run businesses more than 500 people. the millions of businesses that generally are having a very hard time. so, it's not a matter of bigness or smallness. ultimately, it should be those businesses that help sustain communities versus those that prey on them. >> congressman, it strikes me this has become a thing that is political can't. you are never going to get up in the well of the house and say i proudly bring before today this bill is that going to stick it to small businesses. i mean, but if you say this bill is going to be great for small businesses whether or not it's the case, you give it this kind of legitimacy. >> you are right on both counts, i'm not going to stick it to small businesses. but, you know, it's not a term in search of definition. it's a term to avoid definition. that's the deal. everybody wants to be quote, for business. the real internet is very dissatisfying to the government of iran. there is all sorts of stuff on the internet the iranian mullahs do not like so they've been busy closing off bits of internet to the iranian public. you can't use google. now you can't use youtube. you can't use specific sites where the government doesn't like what you can read there or what you can see there. they've been doing that forever. kind of playing with the internet. iran's government is apparently getting tired of managing the increasingly complex patchwork of things they want to block the people in their country from seeing online and so instead they have a genius idea. they are suggesting they may just close off access to the real internet all together and instead build themselves their own internal government approved internet. just for their own country. it's not really an internet. it is more like an iran-ternet. they will build their own separate but equal. ridiculous right? but you can understand that sort of controlling dictatorial impulse here that gives rise to that sort of ridiculousness. i the government should make the call? >> there you go again, chris. >> i know. >>> the gallup tracking poll has now divided into two. >>> if look at the pollster trend line of -- you can see obama in the blue line really picked up. we all know that charlotte was good for the democrats, but romney started gain rapidly following that debate. what do you think about that, michael? how is it moving between now and 28 days from now? >> now, how the people digest that remains -- sugar high? how long does it last? >> whatever it was, obama should have had some of it. the poll, the tracking is beginning to reflect -- >> we're getting into the big issues tonight and for the coming two presidential debates. >> i think that joe biden is going to draw up big. everyone wants to know if everyone's going to do it. to some extent i think it will be like nascar. is he going to make a mistake? the democrats have argued that romney's claim during last week's debate, it's actually a plan to cut $5 billion in taxes, but he did it again tonight on cnn just a short time ago. the obama attacks are false, let's see wha , a lot of government jobs added. but for some reason, i've always been told you need 200 to 250 to make a dent. 114 got a 300 basis point drop? it's crazy. and there's a reason -- you know what they're calling people that are saying this. they're calling help truthers. throwing them in with the birthers. >> i don't believe that there was conspiracy to make the jobs number -- >> i know that. and anyone that says that will be called a truther. so you don't say the government's lying. you can't say that. yet if you add in two months more government workers than at any it time since 1948 for the past two months, the government can do -- >> but that goes to his point the u-6 number is -- i don't know if it's more accurate. >> it's broader and takes in to account the part-time workers that don't want to be part-time. they want the full-time job. so it's a broader measure of giving us the breadth of the labor market and the health of it and that's why when i say the unchanged number, i sort of ignored the headline number and didn't think it was that big of a deal. >> normally we'd focus on the a lasting government that represents all of them. and i'll vigorously pursue the terrorists who attacked our consulate in benghazi and killed our fellow americans. >> eli lake with the daily beast has been out front on the libya story from the beginning with what the u.s. knew, when the u.s. knew it. he joins us once again with increasing information on this. so, i want you to clear up something. you've been reporting today about the militia and some leaders of that militia in benghazi, who were allied with our mission there, but then said we're done with you because you don't like who we support for our new leadership. was that accurate? were they threatening to pull that work away and leave us less protected? >> that's based on the notes of september 11, 2012 cable that was approved by ambassador chris stevens on sort of the benghazi situation overall. it was one of the most interesting bullet points in the three page cable back to washington and i think it shows that in libya right now, there is an effort to try to build serious national security institutions, but those are very early, th in power coming up in china. typically there is inaction on the part of the government in terms of huge programs where it be stimulus or not. many expect you may not get something substantive still march. there's also a great deal concern about the financial system. you hear it a lot. we all talk about the lack of validity of many of the statistic that is we still rely on. but within the financial system itself, where the debt really is, a number of metrics that are followed and thought to be worthy of following are not looking great. there's continued concerned. >> we're running smack into -- our companies have to tell the truth. but there's a huge cohort of companies in our company that don't need a whole lot of growth. so we're funneling into winners and leaving aside cyclicals as losers. >> world bank goes from 8.2 to 7.7. if you think 5 to 6 is the real number, should we be bracing for more -- >> yeah. look, these guys want to do everything incremental but the data's bad. i saw someone recommending gm today on strength of china sales. everyone wants to get ahead of the turn. but no 'm not going to be highly successful of lowers taxes. and likewise those who are reliant on government are not as attracted to slimming down the size of government. it is not elegantly stated. i'm speaking off-the-cuff in response to a question and i'm sure i could state it more clearly than i did in a setting like that. i'm sure i'll point that out as time goes on. >> joining me now msnbc's alex wagner and chris hayes. the first round of this, he went the rush limbaugh route and explained the comments. he said this is such a golden opportunity. this could be the opportunity for the campaign to take the gloves off and explain conservatism. tonight he says, well that comment i was completely wrong. >> yeah, you know, lawrence the word that has popped into my head in the course of the last 4 hours was labotomy. that is the ome way they are going to believe in the things that he is saying or he has had one. which is the explanation for this pivot. i think what struck me last night was there was btn't the attempt to defend this positions to his tax plans to this position on education fundi government officials have confirmed the committee that prior to the september 11 attacks, the u.s. mission in libya made repeated requests for increased security in benghazi. the letter goes on to detail a series of attacks and incidents in libya that formed the basis for those calls for more security resources, resources that the letter alleges were denied by officials in washington. we'll have more on that angle shortly. first, arwa damon joins me. she's back from libya and joins me here in new york. very good to see you safe and sound. walk me back. you were at the site three days after the attack. you have some still photographs that have never been seen before. describe what we see. >> well, the first in these photographs is basically the exterior of the main building at the compound itself. this is the building where the ambassador resided, and the right hand portion of the building is where the so-called safe room was supposed to be. as you can see, the burning all occurred inside the building itself. >> it doesn't look very touched on the outside. >> no. very much a lot of the dama of american activists are spreading that around in pakistan. live from islamabad. >>> a new government report shows two companies that employ thousands of americans may actually pose a security concern for the united states. >>> nascar drivers are questioning their safety after a 20 car pile-up at one of nascar's most famous tracks. why one driver calls it bloodthirsty. >>> the obama campaign launching a counteroffensive to a speech th hasn't happened yet. >> reckless. immaturish. that's what news media and fellow republicans called mitt romney's gaffe-filled july tour of england, israel and poland. >> that's what you call a prebuttal. prebuttal. "newsroom" starts now. -- captions by vitac -- www.vitac.com >>> good morning to you. happy monday. i'm carol costello. that's where we begin on the campaign trail. president obama is raising cash. mitt romney is raising concerns. this morning he's ripping the administration's handling of the middle east and its many recent flash points like the fatal terrorist attack on the u.s. consulate in libya. romney is trying to polish his own spotty record on ? is restriction not one purpose of progressive taxation? is not most of what government does, from agriculture subsidies to subsidized student loans to entitlements, the restriction of well the from one cohort or region to another? thank you george will. steve, i've been trying to explain that to mitt romney that every form of taxation is restriction. i, too, would love to hear him called on that one. >> yeah. if we're talking about the whole restriction in this debate tomorrow night, i think it's a symptom of a broader problem for mitt romney and that is we're basically talking about the stuff that he's been talking about to appeal to the republican base. the idea that obama is a restrictioni restrictionist, this is something that has emerged within the base of the republican party that animates them but we have seen that for four years. that image of obama does not have resonance with the swing voters. so romney has been pitching that to the base and he continues to talk about it and his campaign continues to put it out there. if you're talking about that in the debate you're not winning ove of the federal government. jp is cooperating with the government group and if this lawsuit works it may have some power and fuel. >> can i ask a cynical question? i looked through the lawsuit and looks like so much of the plaintiff lawsuits. >> sure does. >> plaintiff attorneys brought the exact same civil case. >> right. >> why do we think this is going to be a new model for anything? >> they say it's a model for the feds and the state attorneys general to work together. new york has this martin act that other attorneys generally in new york have used quite a bit in the past. >> to the extent that they bring more cases like this, civil cases, do you think this does anything to feed the public's lust for whatever you think, whatever you think president obama was trying to go for a year ago when he created this group in. >> if the public is lusting for ceos being perp walked over the financial crieses they're not going to get it with this and may not ever because they haven't been able to build the criminal cases, they're tough to make, if there was criminal conduct you have to get the lower execu security in the u.s. because of their ties to the chinese government. the report says the companies have records of intellectual property violations and alleged ties to iran. it also says, quote, china has the means, opportunity and motive to use telecommunication companies for malicious purposes. they call it dangerous political distractions and they say its products are safe. >>> hugo chavez overcomes the strongest challenge to his political future to win his third term as president of venezuela. analysts says the results show chavez is weaker politically in that country. paula newton has been following the vote for us in caracas. good morning. >> good morning, soledad. 10%, he won by 10%, wouldn't seem like any kind of a political victory for the pop position but it was significant in venezuela. when you consider he took every lever he had in the state and that was money and he threw it at this campaign, not in a traditional way we're seeing with ads back home but more in the way of getting people refrigerators, cell phones, new homes, he did everything he could. as a result the econo is a governmented orator, he is very good at rhetoric, and i think is he very relatable so i think it's two different people, and i think it's going to be a great night. >> have you talked to ryan at all about his debate performance, what he needs to do, that whole thing? >> sure. paul is one of my very good friends. i talk to paul all the time about a lot of different things, but i think he is taking it very seriously. sure. i think both parties should be nervous. i mean, it's a big night. it's a big -- it's always going to be a big night. >> do you think it makes a difference? there are a lot of people who say, look, the debates are a side show. it's all about the top guys. do you think that ryan has to keep the momentum going from what was widely seen as a mitt romney win in denver? >> we had a od week last week. there's no doubt about it. we have to have a good week this week and the week after, and i think we take it one day at a time. you know, i don't know, i think that the vp debates are very important. you saw in our presidential primary season, candy. we had, what, 22 debates, and the president has been clear in standing up for our values, in holding governments accountable for protecti protecting americans and going after our enemies. there's no question of leadership. if you look at the polls, they say that the american people have more faith in obama. >> we've heard it from governor romney before about not standing with the green revolution at the time. is that a mistake? president obama wish he had a do over on that? >> if you go back, you'll see he stood up for the universal principles of the speech. >> he was dragged to it and it seemed only after there was a lot of cell phone video. >> we were hearing a lot. i was in the administration at the time working middle east issues at the pentagon. we were hearing a lot from iranian opposition members. don't get too close because it will give them the excuse to put the hammer down on us. there was a real dilemma about getting too close that would allow tehran to do more harm. the course the president chose was the responsible one. >> in this memo here where you criticize the various parts of romney's foreign policy, y founder and what the real role is of the chinese government in terms of potential control of this company. >> no, those are also fair points. there is no role of the chinese government in the company. the committee knows full and very well that when they visited our facilities, that they actually had access to the entire list of all 65,000 of our employee shareholders. look, this industry -- the committee is focused on cyber security concerns. those are very legitimate concerns. but, the fact of the matter is, it's a global industry. hauwei, cisco, eriksson, nokia se seimens operating on a common stage with overlapping -- there are cyber concerns but they are universal. anything short of universal solutions is nothing but political gamesmanship. >> i've done a lot of reporting on it. it goes back to the chinese, broadly speaking, to spy, usually using the internet on u.s. corporations and to steal their secrets wherever they may be and whatever way the chinese can. many say about hauwei, in fact, it came from virtually nothing as a result of today because of stolen intellectual property. to support a lasting government. >> how about iran? >> prevent them from acquiring nuclear weapons capability. >> that's the same. >> this is the same guy who couldn't even go to the olympics. >> he will say anything, he will do anything. >> his mention of russia. >> without question of number one geopolitical foe. >> there are two kinds of success, initial and ultimate. >> i still believe you in and i hope you still believe in me. if you vote for me in november i'll finish what we started. >> with four weeks until election day, the romney etch a sketch machine is furiously trying to erase every crazy thing mitt romney has said. in a foreign policy speech mitt romney contradicted what he said on a secretly recorded tape. here's what he said on the tape. >> the palestinians don't wanting to see peace anyway, and these thorny issues and i say there's just know way. so what you do is you move things along the best way you can. but you recognize it's going to remain an unsolved problem. >> and today, the guy who said there's just no way. the no way guy. that guy. the guy who said it is going to r continued growth in professions in business and also in local government, education, and more importantly in health care and those are areas that i know something about, i've been traveling around the country and we're seeing more investments in manufacturing and high-skilled labor areas and that's where you need to play the focus and we need congress to cooperate with us to make sure we can go. >> we can go through all of the talking points we do every month, madam secretary. congress needs to do more and i want to read you one tweet for jack welch who used to run general electric and a man who knows a bit about economic data is created and this is his tweet this morning, madam secretary. unbelievable jobs numbers. the chicago guys will do anything, can't debate, so change numbers. what do you say to him? >> i would say that i have the highest regard for our professionals that do the calculations in the bls. they are highly skilled economists trained in this area, and you have to look at two surveys that have been done. the payroll as well as household survey. you see where those two bit should pick up the slack for the government. he didn't back down from that belief in an interview with a local abc affiliate in michigan. >> the best thing to prevent violent crime is to bring opportunity in the inner cities. help teach people good discipline, good character, that is civil society. that's what charities and churches do to help one another make sure they realize the value in one another. >> but the truth is many charitable organizations are stretched to their limits. a study from the nonpartisan group bread for the world points out the flaws in ryan's plan. ryan's proposed cuts to the nation's food stamp program would mean every church in america would have to come up with approximately $50,000 de dedicated to feeding people. not only that, they'd have to come up with $50,000 every year for the next ten years. would your church or house of worship be able to come up with that kind of money so the wealthy can get their tax breaks? joining me tonight is sister simone campbell, leader of the nuns on the bus. sister, good to have you with us tonight. let's do the math, think what you've seen the last week is more where he really would be when it comes to governing. i think he's had to do a lot of things. he's had to pretend in a way that's damaged his image and his credibility. he's had to pretend to get conservatives excited. now conservatives are so frustrated with the campaign they'll take anything, they'll even take a moderate mitt so he has extreme flexibility for the next couple of weeks. and he has to seize the moment. >> well, i've got to tell you, i was excited, mika, during the debate, two things i saw. one, him focusing on how he was bipartisan, how he got things done in massachusetts, how it made me meet with democratic leaders every monday. i loved that. americans love that. they're hungry for that and i'm so glad he did it. that's one. and two, i loved it, i said it yesterday, i will say it today, i loved him saying i will not cut a tax that will raise the national deficit. now, everybody can obsess on his 87 -- and obsess on what he said during the primaries. but that sent a message to me, jim vandehei. >> of the philosophy. >> that national government to push through are tax cuts on the wealthy. they won't close deficits, they won't do a lot of other things they say, but the one thing they will do, you can bank on it, is cut taxes for the rich. and that is hanging around him. people saw how that worked the last time. they're going through a recession that has hammered the working class in the way it has benefited the wealthy. and on top of that, he wants to do these tax cuts for the rich. that is the core truth that he has to defend. >> it is hard for him to connect with the middle class when he offers a policy like that. it's more of the same, no doubt. i want to go back to what ezra was talking about, about the economic model that the obama administration had and talking about where unemployment was going to go and how good it was going to be. all of that discussion was being presented to the american people, not knowing that we were going to have is a record amount of filibusters. obstruction is not an excuse. it is a reality. and i believe the president has an obligation tonight to make sure that he points that in our government in a way. and ontime responsible people are doing to control it. and the idea that donald trump, jack welch, rich people with crazy conspiracies, can get traction on this is a bad trend. >> i assume, david, there's a number of people that believe that the real unemployment report is somewhere safe in nairobi with the president's kenyan birth certificate. this stuff is crazy. and the notion, quite frankly, that somebody as well respected as jack welch would go on television and embarrass himself for the entire day of friday by saying somehow that these statistics are made up, i agree with chuck, it's incredibly dangerous. and we wonder why institutions in this country are -- or the perception of institutions in this country are failing because people go on tv and just make stuff up. asked for evidence, he said he had none. >> the bush statistics came out after jack welch did and said there is no way this could be. it's not possible. >> when did you stop beating your wife? >> no, no. you guys are missing the whole point. the reason people are losing respect for w themselves about how he would govern. would he take the lead in bombing iran if the mullahs were getting to close or just back up the israelis one of his senior advises asked. would he push for peace with the palestinians or live with the status quo? he's left himself a lot of wiggle room. if they don't know, who does? >> steve clemons is editor-at-large and david corn has a new book out tomorrow. you broke that story. steve, i'm going to be pretty broad here and just start with my critique of romney. every time he speaks he lists more fronts he wants to get hotter and he wants to stay in longer whether it's afghanistan or iraq, he wants to go in deeper. should have gone in deeper on libya and syria. should be tougher on drawing a bright line earlier than anybody but the israelis in terms of the iranian nuclear threat. everything is go to war, go to war. name anyone in his family history going back or forward who has ever put on a military uniform. they have no intention of participating in all these wars in any way and yet he wants to fight it as an instinct. it doesn't square. you can' ." he's been a democratic presidential campaign adviser since 1972, working with george mcgovern, jimmy carter, bill clinton and al gore. professor, great to have you hire. let's start with thursday's vice presidential debate. what does joe biden and paul ryan have to do to outdo each other, to win? >> well, the job is not to be gladiators, because it doesn't matter which of them is better in a cage fight. the question is what can they do to strengthen the way people approach the presidential debate. biden has to find a way to put romney on the spot, not ryan on the spot. >> andrew sullivan has a new article on the daily beast website called "did president obama just throw the entire election away?" and he writes in part, "i've never seen a candidate self-destruct for no external reason this late in the campaign before. i'm trying to see a silver lining, but when a president self-imlates on live tv and his opponent shines with lies and smiles and a record number of people watch, it's hard to see how a president and his party recover." professor, forget the debates, how does president ob 's about, piers, we can't go on like this with unemployment this high and the government functionally bankrupt and chaos abroad. i think the debate's going to be about that. i think if they stay on the substance, i'm hopeful that governor romney should do very well, even if he fumbles a little bit because he hasn't been in this kind of a format before, because you know, i think the country knows we need change and i think if he stays on that message, he should do fine. >> are you setting the bar so low that we should now expect a fumble? >> no. he's a pretty good debater. i don't think he's going to fumble. i'm just saying that this debate's going to be about i believe the issues, which is where we are now and how we can fix it. and if it stays on that substance, i think that's what the voters will absorb rather than whether either one of them hems or haws a little bit. >> this is mitt romney joking about rob portman playing president obama in some of the rehearsals. >> do you know what he does on weekends? do you know what he does? he plays barack obama. can you believe that? he does of congress. in celebration of over 75 years of our government employees insurance company, or geico...as most of you know it. ...i propose savings for everyone! i'm talking hundreds here... and furthermore.. newcaster: breaking news. the gecko is demanding free pudding. and political parties that are actual parties! with cake! and presents! ah, that was good. too bad nobody could hear me. geico. fifteen minutes could save you fifteen percent or more on car insurance. sailing, diving, post guard beaches. how shelley tyre looked forward to it. they had chartered a sailboat with their friends. the other couple would be bringing along their young son. a week of diving and sailing whichever way caught their fancy. upon arrival here in tortola, they went to get scuba gear. the women went for their boat the caribbean soul. and to this day no one in that group can say that anything was amiss. and it was by all accounts the leisurely week in the caribbean all hoped for. they dove the british islands' greatest hits. on the morning of march 12th, they set a course for cooper island and the site known as Excerpts 0 to 86 of about 87 results. 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x subaru x gabby giffords Set Clip Length: the time. they want to move on to cleaner fights on energy reform or other things and have this off of the deck. >> okay. chris, let me bring you in. you heard a.b. say that grover norquist, who is not an elected leader surmised there's no mandate. the vice president actually on a ballot, here's what he believes came down on tuesday. he said in part, there was a clear sort of mandate about people coming much closer to our view about how to deal with tax policy. i just think he it's going to take time for the republicans to sort of digest what the consequences are for them internally. what's your reaction to at least biden believing there was a mandate for their tax policy? it shows in our exit polling that a significant number of people were okay with a tax increase for people who make over $250,000. >> my perspective is elections have consequences, and to the winner there is a certainly significance that follows from it. when you look at the exit polls in particular with the one you just referenced, 60% of the voters sided with the president's position on raising taxes on those mak Excerpts 0 to 7 of about 8 results. (Some duplicates have been removed) Terms of Use (10 Mar 2001)
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x google x ABC7 News 400PM Set Clip Length: in hawaii. but don't you worry, we will always be together for christmas. [ male announcer ] being together is the best part of the holidays and cheerios is happy to be part of the family. you just ate dallas! >>> in connecticut today funerals took place for two 6-year-old victims of the sandy hook elementary school massacre, now, we're learn morgue about the killer from a former friend. ways freshman where lanza was a sophomore, both members of the tech club. >> very intelligent person. just like the way he acted around other people was just very with draub drawn, and just quiet. he had a nerd look. like you know khaki pants, belt, tucked in shirt. he had little computer hit. -- kit like a brief case instead of a backpack and a pocket protector. at one point he was a good kid. the event he did that day, may have been evil. before then, he -- he was just another kid. >> he says he lost touch when lanza left high school for home schooling. >> officials in texas including the governor, rick pee$ prevent school shootings. governor perry says knee jerk gun control legislation snot the answer. h Excerpts 0 to 0 of about 1 results. Terms of Use (10 Mar 2001)
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x NBC Bay Area News at 11AM x north korea Set Clip Length: .a.r.t. station where dallas used to sit. >> he was a really sweet man. he always helped those around him, whoever needed it. he always helped me and i always helped him. he did lead a quiet life. >> reporter: at 77 years old, he sold the chronicle and other papers for decades. >> the victim was working, had taken a break on the sidewalk, a suspect approached him, said something to the victim then put him down on the concrete. >> reporter: he suffered hip injuries and after weeks in the hospital, he died. the investigation now a homicide. customers today left flowers saying they can't believe it. >> pretty awful, particularly you know, you don't really expect that in this area particularly. and you know, you hear about these stories of people being pushed in front of trains in new york and that kind of stuff. i haven't heard of anything like this. it's really awful. >> reporter: it was 11:00 a.m., the financial district. witnesses got him back on his feet. miller believes ayers may have been robbed. his wall let was missing, but investigators say they don't believe anything was taken. what is gone and within our sense that god remains with us. >> it will definite ly take administrative part of the church. but in terms of believing in the lord, it doesn't change that. >> reporter: father benedict hopes that catholics consider this to be an experience in which to feel the continuity of the church and faith. there will be a special mass at 7:00 tonight here at st. joseph cathedral and it will include san jose bishop patrick mcgrath. they'll be celebrating the pope's retirement and praying for a smooth transition. we're live in san jose. i'm arturo santiago, nbc bay area news. >>> pope benedict xvi is the first pope in 600 years to resign. it is a very big deal. mary ann ahern is live in vatican city. what's the atmosphere like out there right now? >> reporter: it has been a most unusual day, marla, very dramatic. when the pope met this morning starting out his day with cardinals, you could tell that they had so much affection for him by their applause. each one stopping and speaking to him. and even a few handing him notes. he had words for them telling them that he would be obedient to Excerpts 0 to 1 of about 2 results. Terms of Use (10 Mar 2001)
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x illinois Set Clip Length: to be confronted in the next weeks and months as you and the chairman pointed out is the debt ceiling. i hope we have all learned from our experience in the summer of 2011 that it is irresponsible and reckless for the united states to suggest that it will not meet its financial obligations. the there's bondholders, social security recipients, due to other people have contracted with the united states government. in the house in the next couple weeks, we are expected to take up a bill that says, you know what, we can prioritize their deaths. based on that book take on first, but other debts and obligations including this congress have taken on, they don't have as high a priority. could you, mr. secretary, secretary of the treasury comment on what impact it would have on our economy and the signal is sent to the international communist united states were to default on any of its obligations? >> congressman, that notion you prayer a case which is the obligation congress authors should be paid is one that just doesn't work. hhs would obligation your defaulted non. we have never in the history defaul to have runs. fourth him of the debt ceiling was going to derail our economy for certain, even if we manage to solve the fiscal cliff and the sequester lurked ominously. no matter what deal the politicians made. these would have course throw us off track and cause much higher unemployment. finally, four months ago, fourth quarter earnings, the reports were right around the corner and they were supposed to be, yes, nothing to write home about, or maybe worse, particularly the worldwide slowdown that europe seemed to be mandating, we could have huge downside surprises and the last time we had some pre-announcements -- wait a second. what actually happened? how about we had the best first quarter in 15 years. how is that possible? i think it's because the market has changed its animals. i'm not kidding. investors stopped being scared of washington or europe or earnings shortfalls and they decided to embrace the future, not spurn it. they became like ulysses and his crew, strapped to the mast, oblivious to the sell, sell, sell sirens of the saturnine set. where is sappho when you need h by the republicans in the house to increase the debt ceiling. at the end of the day, we got $2.5 in spending. restrapets that was the cap and the sequester. there's been repeated efforts by democrats in the senate and the white house to undue that agreement of august 2011, but it has held. the sequester is holding despite not letting kids go through the white house or the easter egg hunts and not letting the blue angels fly. this is the boy cried wolf kind of thing. at the end of the day, taxpayers won that fight. those who believed in d.c., you had to raise taxes in order to get any spending restraints. we're wrong. we got the -- they were wrong. obama -- president obama is again saying i will never let you cut the budget unless you give me tax increases. he said that for the last three years and he has lost several times on that fight. does he want to have spending restraint or entitlement reform? don't think so. democratic senate with 59 or 60 votes. he woke up every morning and he could have reform entitlements but he didn't, he went to bed. someone could do something for 00 days like qu that was demanded by the republicans in the house for the increase in the debt ceiling. at the end of the day, we got 2-1/2 trillion in spending restraints. the caps and the sequester, have been repeated efforts by democrats in the senate and the white house to try and undo that agreement of august 2011, but it's held. the sequester is holding. despite the historianics of not having easter egg hunts or not letting kids go through the white house, not letting the blue angels fly. they do that and looks silly, the boy who cried wolf. and at the end of the day we taxpayers won the fight, and those who believed in d.c., you had to raise taxes, in order to get any spending restraint, were wrong. we got suspending restraint without the tax increases. obama -- president obama is again saying'll never let you cut the budget unless you give me more tax increases. he said that the last three years and has lost several times on that fight. so does he want to have spending retrain or spitelement reform? -- restraint or entitlement reform? i don't think so. just look backwards. his first two years a democrati of what we call the debt ceiling which lets the country borrow money to pay its bills. as a part of that agreement, a large number of people from both parties voted for something that hasn't turned out very well. and it's called sequestration. this is a word that gets tossed around in this chamber. it is having a real and negative impact on the country. i just came from a hearing of the armed services committee where the chairman of the joint chiefs of staff and the secretary of defense told us that nine battle groups and three bomber groups of our air force and our navy planes have been grounded. about 1/3 of the nation's air capacity isn't flying. across the country today, people who are on medicare, who need chemotherapy treatments from their doctors offices are finding that many doctors are declining to do chemo therapy treatments for cancer patients because of the cuts that take place in sequestration. i met earlier this week with employees of the naval sea systems engineering command in philadelphia whom i represent. they're looking at a 20% pay cut because of furloughs. th approaches the debt ceiling to say, how are we going to tell the people that we are going to pay off the debt that we've now gone ahead and incurred? and i think a little bit of forethought here, planning into the future, how we're going to pay the bills is the emphasis. and i've always agreed, as the gentleman said, the debt ceiling is something that is necessary for the operations of government. we'll bring a bill forward that will ensure that we don't go into default, but i do think that we should be mindful of how we're going to tell the public we're going to go in the future and pay off these debts. because as the gentleman has many children and grandchildren, he doesn't want his kids nor do i want mine to be shouldering the debt and paying our bills. we should be really committing ourselves not to just borrowing more, not to just taking more from taxpayer dollars because we've done a lot of that this year already. the gentleman talks about the need to proceed with revenues. we already have close to $650 billion i of additional static revenues, taxes that are accounted for because of the . the houseebt ceiling, will move now to put its priority in place. we will move now early to reassure people that america will pay its debts. we are serious about tackling our problems. affected sequestration your district? guest: it has not. people laugh when you talk government0-pound being forced to lose 10 pounds. closing local air-traffic towers. they think it is a small step in the right direction. host: was it a political victory for republicans? guest: it helped reassure americans that we were serious about making some small but important steps in the right lowerion, walking those levels in was important -- locking those lower levels in was import. i believe we have the political courage to get this done. we have laid out courageous steps on medicare and medicaid to solve those. the president is willing to take some small steps towards us. host: wallace is a republican in dallas. caller: good morning. thank you for taking my call. police officer and i collect revolvers. my comment for the representative is that i have been leery when the government starts talking about protecting my Excerpts 0 to 7 of about 8 results. 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You are here: AU » About Aarhus University » Department of Bioscience » Studies As a biology student you meet life on our planet from the smallest viruses to the largest whales. How did the forms of life begin? How do they interact in nature, and how do we manage our countryside? How are living organisms built up, and what physiological and behavioral adaptations enable survival in different habitats in a changing world? What determines the number of species and the spread of them? And what will be the biological consequences of global climate and environmental changes? At the Department of Bioscience you will have the opportunity to work with a wide range of biological problems. A degree enables you to work scientifically with such issues on the basis of independent experiments and analyzes with the guidance of scientists at the forefront of the latest developments of techniques and know-how. You can find general information about studying biology, and you can find information targeted at Bachelor and Master’s degree students click on the pages below. If you are interested in the PhD programme, you can read more on the Department's PhD portal. Comments on content:  Revised 2013.08.28 Aarhus University Nordre Ringgade 1 DK-8000 Aarhus C Tel: +45 8715 0000 Fax: +45 8715 0201 CVR no: 31119103 AU on social media
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The Milwaukee Bucks' roster is certainly different for 2013-14, but does that mean it's any better than before? With a seemingly never-ending mandate to "just stay competitive," the Bucks were active throughout the summer. Trading Brandon Jennings for Brandon Knight and ostensibly swapping Monta Ellis with O.J. Mayo via free agency will certainly cut down on the attitude headaches. Yet, how much upside does either player have left? Larry Sanders and John Henson appear to have bright futures, and one might eventually add rookie tongue-twister Giannis Antetokounmpo to that mix, but the roster still feels devoid of stars. Why then did they round out the crew with "luxury items" (i.e. minute sappers) like Carlos Delfino, Caron Butler, Zaza Pachulia and Gary Neal? The Bucks may actually be more competitive this year with Larry Drew at the helm, but they will probably matter even less in a much-tougher-than-recently Eastern Conference. NBA Featured Columnist Dan Favale joins assistant editors Ethan Norof and Joel C. Cordes for the latest episode of Basketball by Association. We look at the best and the worst of the Bucks' offseason along with the biggest questions heading into 2014. We'll also detail Milwaukee's keys to a successful year while predicting its final position in the standings.
http://bleacherreport.com/articles/1778076-nba-podcast-2013-14-milwaukee-bucks-season-preview
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Signs of low-grade depression 1. You feel sad, dissatisfied or pessimistic most of the time, although you still have days when you feel normal. 2. Your appetite changes. 3. You're tired most of the time. 4. You have insomnia or you're sleeping too much. 5. You're The Day by Pat Sanchez on February 16, 2012 It is raining and the drops on the window match
http://blogs.fanbox.com/Itisrainingandthedropsonthewindowmatchth
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Shawne Fletcher, L.A. County Jail Inmate, Sues Sheriff Lee Baca for Another Brutal Beating shawne fletcher.jpg Courtesy of Dawn Fletcher Shawn, after the beating. Allegations of abuse have been raining down on the L.A. County Sheriff's Department since springtime. LA Weekly writer Chris Vogel's "Men's County Jail Visitor Viciously Beaten by Guards" opened the floodgates for more testimonies, and lawsuits, from inmates who say they were subjected to a terrifying culture of violence that deputies have created within the prisons. (As if being in prison wasn't bad enough.) Though a recent high-profile ACLU report aired hundreds of shocking victim testimonies, and triggered a larger FBI investigation, inmates have been struggling to unveil the sick reality of the department, under the non-leadership of Sheriff Lee Baca, for years. Take the case of Shawne Fletcher, currently in U.S. District Court: Fletcher filed a lawsuit in 2008 claiming that on June 18, 2006, he was grope-searched and beaten senseless by a pack of deputies at the Twin Towers Correctional Facility while waiting in line to get pills for his mental illness. A video interview of Fletcher a few days after the incident shows his left eye still swollen beyond visibility and his lips so bruised he has trouble speaking. As is policy, deputies grill him about what happened, but he has trouble answering their loaded questions. "[A deputy] yanked me off the wall, and when he yanked me, I lost my balance," Fletcher tells his interviewer. "And I just fell into somebody, and they just kicked my ass. They stomped the shit out of me -- that's what happened." "You just fell into this deputy, or you grabbed him?" the lady deputy asks. "They yanked me off the wall." "My question was, did you not pretty much bear hug this deputy? Your arms went around him." "Did they?" "I'm asking you." "Are you asking me, or were you there? ... Because I don't remember. I remember being yanked off the wall and losing balance and then I ran into somebody." "Did you hit the deputy?" "I never swung at nobody." "You never hit any deputy?" "I never swung at no deputy." "But did you ever hit a deputy?" "How am I going to hit somebody without using my hands? I never swung at nobody, I don't remember that." The back-and-forth continues on like this, with the interviewer trying to get Fletcher to say he fought back when the deputy slammed him against the wall, and a disoriented Fletcher insisting the only thing he remembers is coming under full attack -- pepper spray, hard boots to the ribcage, the works. "Did you not spit at the deputies?" she asks later on. "Spit? I was bleeding," he answers. "Did you spit at the deputies?" "I couldn't breathe. What are you talking about? My face was down on the ground. When I came through, I was laying in blood." "Were you continuing to fight the deputies and try to get up?" "What? I couldn't breathe." And so on. Unfortunately, Fletcher can't afford a lawyer, so he wrote the entire lawsuit himself; it's riddled with court-unfriendly language like "Deputy Eagar then began searching my celly" and "This doctor is on some gay shit man!" But his sister, Dawn Fletcher, says learning about the legal system and how he can fight for the future safety of powerless inmates like himself have helped him get through the rest of his time in prison. She says he's set to be released next month. A witness statement from inmate Michael Baldwin, included in the lawsuit, sees the beating from further up in the "pill call" line, outside Fletcher's immediate pummeled sphere. Baldwin alleges the following (stet throughout): "As we were lined up against th wall faceing away from the med line, deputy's started to make comments to us to not look around. The deputy's started to kick inmates feet and also search us, myself as well. As doing the search [they] were handling [our] privet part with force. Makeing a lot of guy holler out in pain [and slamming] there heads on the wall causeing more pain. After I was searched, I looked down the role a bit and I can see a problem going on. And then I see deupty's hiting Mr. Fletcher, about the face area. Then they drag him out the line still beating him. Deputy's drag him to the other side of the wall by the mail box. [Where] at this time, [the] deputy's started slaming his head into the mail box, blood was flying everywere. By this time there were anywhere from 8 to 10 deputy's hitting him stomping him he looked to me to be [unconscious] at one time. His head was so [swollen] one couldn't even see any eyes at all. ... Actually I thought Mr. Fletcher was dead. But before they dragged him out they [pepper] sprayed him in the face and then put a black mask on his face. We never seen him [again]. Two day's later they do the same thing to another inmate." Pretty much lines up with the ACLU allegations and the many tragic tales that are just now emerging after what appears to be years of almost haze-like bullying within America's largets jail system. (Just yesterday, Vogel wrote of another man, Troy Duncan, who's suing after he allegedly got his head bashed in by deputies while merely visiting someone in an Altadena jail.) "Los Angeles County jails are rapidly developing a reputation as perhaps the worst in the nation," Margaret Winter, a Washington, D.C., attorney who leads the ACLU's National Prison Project effort, told Vogel in March. "I'm basing that it's the worst on that I've never seen this accumulation of violence. The severity, the frequency and the boldness is stunning, and I believe unprecedented." Apparently, the bloodied inmates have been trying to tell us that for years. My Voice Nation Help Once the sheriffs have a person in their custody they have an obligation to care for them in accordance with their own policies and the laws. I think there is a widespread systemic problem of officers abusing inmates and it must be stopped. The sheriffs must do their jobs right. When sheriffs gang up and bully a person they are the criminals in uniforms under the color of law. Any officers that use excessive force are in violation of the U.S. constitution and should be sued!! Even if Shawne has some form of mental illness that does not mean he is deaf, dumb and blind. As a matter of fact, a mentally disabled person should be all the more protected. It is dispicable for anyone to apply excessive force on a mental cripple. I vote ''GO FOR IT'' to the ACLUs lawsuit against sheriffs brutality! USABeachGirl to Grow up Your picutre is hilarious I could not stop laughing we all need to post our thoughts who are you the Posting police I would pick another picture lol lol lol Cherise Rogers 1 day ago in reply to USABeachGirl PLEASE STFU already! Deputy love to beat up immates they love it ..I hope the fbi get all the bad apples.... Leave Sheriff Baca Alone Leave his Depuites and Sheriff Dept alone my thoughts ACLU pick on someone else why the Hate my thoughs for Sheirff Baca, you were not there so yiou do not know the truth My own opinion. Unless we were in that jail and saw what happened it is hard to belivve my own opionion the words of Shawne Fletcher a man who states he was in jail get line as he is  mentally ill. If this suppoose to have happend in 2006 it is now 2011. He is suing why was He in Jail? This  witch hunt for Sheriff Baca and the Sheriff Dept for all of you it is obivious that these men in jail spit urinate on cuss out etc Deputies. It is also true that Depuites have to take Inmate abuse simple Have lock down let these thugs hoolumds and Criminal stay in the jail cell for 22 hours a day for 5 months. Then the truth will come out and you will see how they inmates beat each other up I find it my own opinion how the ACLU my own opinion seems to know what happened why they were not there only Jesus and Shawne know no offense he says he is mentally ill. My persional Opinion it is a good way after all these years to try and get money My Thoughts My Opinion ACLU No to your asking for Sheriff Baca to Resign my opinion. My Opinion ACLU mind your own bussiness ask Shawne why was he in jail? If what he is inplying hmmmmmmmmmmmmmmmmm he would have brain damage oh plesee LEAVE SHERIFF BACA ALONE. Stop abusing Sheriff Baca and Stop Abuing the Depuites. There are 2 sides to every story and we are only hearing 1 this of a digruanted man his words he is mentally ill accussions. God help this world and Sheriff Baca. My Thoughts My OWN OPINION ACLU why the witch hunt let him do his job, unless you have walked a mile in Sheriff Baca's boots or have walked a mile in a Depuites boots you will never know the abuse they suffer. Sheriff Baca your a good man a kind man and I back you and the Deputies I Pray for all of you. How would you people ACLU (my opinion) like to work at HELL LA Jail be spit on cussed at abused urinated on have to deal with mentally ill people and then be lied on. Sheriff Baca and Depuites I back you 400 % Depuites back you 400% Sheriff Baca alot of people care and are there for you and your Depuites. My Opinion ACLU who do do you think you are to demand Sheriff Bac resign? PLEASE Jesus make these iddots leave Sheriff Baca alone. If he was supposed to be doen what he says he would either be dead in a coma or have brain trauma pleasessssssssssss stop the hate the the lies. You have never walked a mile in his boots or a Depuites boots all you know  is the word of his Shawne mentally ill person no offense it could be all made up for money my own opinion.USABeachGirl You have probably never walked an inch in the bare feet of an abused inmate. You talk as if you could care less if bad cops are applying excessive force on prisoners. Excessive force is a crime and the bad cops that victimize prisoners with excessive force are criminal cops. You better wake up and see reality that some cops are BAD! Cops are not angels from heaven. Cops are human beings too just like everyone else and sometimes cops make mistakes. Sometimes cops commit crimes. Some cops beat their own wives and kids at home. Get real and face reality! A lot of people have been horribly abused by bad cops inside the jail system in Los Angeles county and the ACLU are doing right by sending the sheriffs a signal to STOP victimizing their inmates! Abuse they suffer? People like you are the reason why we will never have a so called free world. One day soon the world will suffer trough a devistating tragedy and the american justice system will fall and evrey man will be equal. And the power will be given back to the strong like in the begining of time and people like you will be raped for a million moons and a day. Ok bitch - explain the 3 drunk Sheriff Deputies in La Mirada Park last night shooting off their guns? Don't you call me a Bitch your gutless, spinelss, creep who do you think you are calling me a Bitch?  Your not a Decent American your a punk abusing me online. I do  believe your mad after getting out of jail ( my opinion) making up stories. If I am a Bitch then it makes your Mother a major Bitch get a life    grow up one day you will be a man punk do not ever call me a Bitch again little Computer creep.USABeachGirl Decent_American 1 day ago in reply to USABeachGirl Ok bitch - explain the 3 drunk Sheriff Deputies in La Mirada Park last night shooting off their guns From the Vault
http://blogs.laweekly.com/informer/2011/10/shawne_fletcher_sues_sheriff_lee_baca.php
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An Open Letter from the President of the United States of Google An Open Letter from the President of the United States of Google • A pure form of communication that is unsullied by cultural context; • Broad adoption by as many as 10,000 speakers • Independent (yet mostly compatible) dialects that not only bring additional choice for speakers also foster healthy competition and innovation We expect even more communication between people in the coming year and are therefore focusing our investments in languages that are created based on constructed language principles. To that end, we are changing the spoken and written language of this nation to make it consistent with the form of speech already supported by the Language Creation Society. Specifically, we are supporting the Esperanto and Klingon languages, and will consider adding support for other high-quality constructed languages in the future. Though English plays an important role in speech today, as our goal is to enable open innovation, its further use as a form of communication in this country will be prohibited and our resources directed towards languages that are untainted by real-world usage. These changes will occur in the next couple months but we are announcing them now to give citizens using other languages an opportunity to translate the libraries of the world into Esperanto. Dankon, nedankinde! • Do not forget that before English, French used to be the international language, and before that Latin, or Ancient if you consider the whole galaxy according to the Stargate canon. And the next one will probably be Chinese. Things evolve. Oh, and, people don't have to pay royalties to speak and write English, unlike H.264. • Via publika letero estus pli frapa se vi skribus ĝin en Esperanto. Mi ŝatus uzi Esperanton pli ofte en la ĉiutaga vivo. Bonŝance mi povas: * Uzi la esperantlingvan fasadon de Vizaĝlibro. * Interparoli kun esperantlingvanoj tie. * Uzi plurajn esperantlingvajn programojn ĉe Linukso. * Uzi la esperantlingvan variaĵon de Farjovulpo. * Aŭskulti aktualajn sondosierojn. * ktp La sola okazo en kiu mi ne povas esti tute en esperantlingva medio ĉe mia komputilo estas, kiam mi uzas viajn programojn kaj operaciumon. Dankon pro la atenton. • Finally, some passion from Microsoft! • Bad attempt to make a joke. Or may be you know, that M$ plans to file some patents on English language usage? For example they can ban using the word "windows" without paying a fee ;) • Anyone and everyone that can't enjoy this magnificent letter must be banned from the Internet for life, so the rest of us can freely wander around, speaking Ido. • I only wonder what does the economic power of China have to say. I'm not that worried about some small companies, who still think they're great. • Since you work for Microsoft, by default you are always wrong. • I detect a bit of sour grapes here, given Microsoft's repeated failures to establish its own standards in these areas. Tell me, Mr. Sneath, what success has Microsoft had recently?  I don't mean PR gimmicks like Surface or OEM Windows N+1, I mean sound, hard, commercial successes with new products?  Heck, even Office revenue is going down. • Well said,  but though it is easy to point fingers at others, those living in glass houses should be cautious and should not throw stones at others. • ..lame. There are many more important issues challenging the world today. I will not waste any further time on this "issue". • Superb !!!!!! Sometimes humor speaks more than 2000 word article. :) • Haha, the Google hate at Microsoft has reached record levels. • The whole world can see how we 'benefit' from Microsoft's own set of webstandards in IE6, and now you mock Google for going their own way?? You hypocrit!! This is why people hate Microsoft... • Brain washed idiot. • Microsoft has no right to preach about Google dropping support to a Microsoft close sourced product. Page 12 of 15 (224 items) «1011121314»
http://blogs.msdn.com/b/tims/archive/2011/01/11/an-open-letter-from-the-president-of-the-united-states-of-google.aspx?PageIndex=12
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Jump to content Jump to navigation Level 1: Joiner Posts: 2 Registered: ‎22-05-2012 HTC One V Signal Problems Hi, I'm currently having a few problems with my signal. It can randomly show no signal and will stay like that forever until I reset the phone. Once it boots up again the signal is fine. This leads me to believe its a software problem rather than hardware. I've tried setting my network mode to either GSM or WCDMA, yet the problem persists. Anyone got any advice or do you think the phone itself is faulty? I've only had it a few weeks. Cheers Please use plain text. Level 1: Joiner Posts: 4 Registered: ‎19-11-2012 Re: HTC One V Signal Problems The HTC one v suffers from the same problem as the HTC legend. The atenna is mounted in the plastic cover which goes over the battery sim etc. When you hold it it attenuates the signal watch the sig strength bar then put your hand around the base.see what i mean. There is a post on the net which improoved the sig on the Legend. I tried it and it seems to work. With the phone turned on remove the antenna cover. sig strength 0 short the two brass contacts in the phone with a paperclip sig strengh goes to full. leave it shorted for 1 min. remove then refit cover. it improoved my Legend. Dont know why seemed to some sort of reset. I now get signal where I didnt before. Obviously my disclaimer is that it is at your own risk. If your not happy try and get the handset change the handset for a different model.  Please use plain text.
http://community.o2.co.uk/t5/Android-Devices-Samsung-HTC-Sony/HTC-One-V-Signal-Problems/td-p/233379
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Donald Finkel Papers 1947-1983 full text File Size: 968 K bytes | Add this to my bookbag box-folder   18-19/136-149   VII. Material toward Answer back (New York: Atheneum, 1968). [series]: (Finkel I) (131 items.)    Scope: Consists of material toward Answer Back, (New York: Atheneum, 1968), including drafts of poems, source material, correspondence, galley proofs, and reviews of the collection. box-folder   18/136   VII. 1. Source material. (Finkel I) (105 items.)    Scope: Consists of editorial correspondence and correspondence from Cleveland Burrell, an inmate at Missouri State Penitentiary, whose letters were an "initiating impulse" behind Answer Back. Includes a note from Finkel describing Burrell's correspondence as a source for the collection. box-folder   19/137-144   VII. 2. Drafts. (Finkel I) (8 items.)    Scope: Consists of drafts of collection, including several early assemblages of poem fragments used to create drafts. box-folder   19/145-149   VII. 3. Editorial matter. (Finkel I) (9 items.)    Scope: Consists of galley proofs, page proofs, advertisements, and a misbound edition. box-folder   19/145-146   VII. 3. a. Galley proofs. Consists of two sets of galley proofs. (Finkel I) (3 items.) box-folder   19/147   VII. 3. b. Advertisements. Consists of advertisements for the book. (Finkel I) (2 items.) box-folder   19/148   VII. 3. c. Misbound edition. Consists of a copy of the misbound first edition; all others were destroyed and the book was reprinted. (Finkel I) (1 item.) box-folder   19/145   VII. 4. Reviews. (Finkel I) (3 items.)    Scope: Consists of photocopies, clippings, and Ts manuscript by Richard Howard, reviewing Answer Back.
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Corpus callosum From Wikipedia, the free encyclopedia   (Redirected from Corpus collosum) Jump to: navigation, search Brain: Corpus callosum Corpus callosum from above. (Anterior portion is at the top of the image.) Median sagittal section of brain (person faces to the left). Corpus callosum visible at center, in light gray Gray's subject #189 828 NeuroNames hier-173 MeSH Corpus+Callosum NeuroLex ID birnlex_1087 Corpus callosum with Anatomography The corpus callosum (from Latin: "tough body"), also known as the colossal commissure, is a wide, flat bundle of neural fibers beneath the cortex in the eutherian brain at the longitudinal fissure. It connects the left and right cerebral hemispheres and facilitates interhemispheric communication. It is the largest white matter structure in the brain, consisting of 200–250 million contralateral axonal projections. The posterior portion of the corpus callosum is called the splenium; the anterior is called the genu (or "knee"); between the two is the truncus, or "body", of the corpus callosum. The part between the body and the splenium is often markedly thinned and thus referred to as the "isthmus". The rostrum is the part of the corpus callosum that projects posteriorly and inferiorly from the anteriormost genu, as can be seen on the sagittal image of the brain displayed on the right. The rostrum is so named for its resemblance to a bird's beak. Corpus callosum Thinner axons in the genu connect the prefrontal cortex between the two halves of the brain, these form a fork-like bundle of fibers known as Forceps Minor. Thicker axons in the midbody of the corpus callosum, known as Trunk, interconnect areas of the premotor and supplementary motor regions and motor cortex, with proportionally more corpus dedicated to supplementary motor regions like Broca's area. The posterior body of the corpus, known as splenium, communicates somatosensory information between the two halves of the parietal lobe and visual center at the occipital lobe, these fibers are known as Forceps Major.[1][2] Species differences[edit] The corpus callosum is found only in placental mammals (the eutherians), while it is absent in monotremes and marsupials,[3] as well as other vertebrates such as birds, reptiles, amphibians and fish.[4] (Other groups do have other brain structures that allow for communication between the two hemispheres, such as the anterior commissure, which serves as the primary mode of interhemispheric communication in marsupials,[5][6] and which carries all the commissural fibers arising from the neocortex(also known as the neopallium), whereas in placental mammals the anterior commissure carries only some of these fibers.[7]) In primates, the speed of nerve transmission depends on its degree of myelination, or lipid coating. This is reflected by the diameter of the nerve axon. In most primates, axonal diameter increases in proportion to brain size to compensate for the increased distance to travel for neural impulse transmission. This allows the brain to coordinate sensory and motor impulses. However, the scaling of overall brain size and increased myelination has not occurred between chimpanzees and humans. This has resulted in the human corpus callosum's requiring double the time for interhemispheric communication as a macaque's.[1] Sagittal post-mortem section through the midline brain. The corpus callosum is the curved band of lighter tissue at the center of the brain above the hypothalamus. Its lighter texture is due to higher myelin content, resulting in faster neuronal impulse transmission. The fibrous bundle that the corpus callosum appears as, can and does increase to such an extent in humans that it encroaches upon and wedges apart the hippocampal structures.[8] Absence and malformations[edit] Agenesis of the corpus callosum (ACC) is a rare congenital disorder in which the corpus callosum is partially or completely absent. ACC is usually diagnosed within the first two years of life and may manifest as a severe syndrome in infancy or childhood, as a milder condition in young adults, or as an asymptomatic incidental finding. Initial symptoms of ACC usually include seizures, which may be followed by feeding problems and delays in holding the head erect, sitting, standing, and walking. Other possible symptoms may include impairments in mental and physical development, hand-eye coordination, and visual and auditory memory. Hydrocephaly may also occur. In mild cases, symptoms such as seizures, repetitive speech, or headaches may not appear for years. ACC is usually non-fatal. Treatment usually involves management of symptoms, such as hydrocephaly and seizures, if they occur. Although many children with the disorder will lead normal lives and have average intelligence, careful neuropsychological testing reveals subtle differences in higher cortical function compared to individuals of the same age and education without ACC. Children with ACC accompanied by developmental delay and/or seizure disorders should be screened for metabolic disorders.[9] In addition to agenesis of the corpus callosum, similar conditions are hypogenesis (partial formation), dysgenesis (malformed), and hypoplasia (underdevelopment, including too thin). Recent studies have also linked possible correlations between corpus callosum malformation and autism spectrum disorders (ASD).[10] Kim Peek, a savant and the inspiration behind the movie Rain Man, was found with agenesis of the corpus callosum. Sexual dimorphism[edit] The corpus callosum and its relation to sex has been a subject of debate in the scientific and lay communities for over a century. Initial research in the early 20th century claimed the corpus to be different in size between men and women. That research was in turn questioned, and ultimately gave way to more advanced imaging techniques that appeared to refute earlier correlations. The new advent of physiologic based imaging has altered the paradigm dramatically, with the relationship between gender and the corpus callosum becoming a subject of increasing numbers of studies in recent years. Original studies and dispute[edit] The first study of the corpus with relation to gender was by R. B. Bean, a Philadelphia anatomist, who suggested in 1906 that "exceptional size of the corpus callosum may mean exceptional intellectual activity" and that there were measurable differences between men and women. Perhaps reflecting the political climate of the times, he went on to claim differences in the size of the callosum across different races. His research was ultimately refuted by Franklin Mall, the director of his own laboratory.[11] Of more mainstream impact was a 1982 Science article by Holloway and Utamsing that suggested sex difference in human brain morphology, which related to differences in cognitive ability.[12] Time published an article in 1992 that suggested that, because the corpus is "often wider in the brains of women than in those of men, it may allow for greater cross-talk between the hemispheres—possibly the basis for women’s intuition."[13] More recent publications in the psychology literature have raised doubt as to whether the anatomic size of the corpus is actually different. A meta-analysis of 49 studies since 1980 found that, contrary to de Lacoste-Utamsing and Holloway, no sex difference could be found in the size of the corpus callosum, whether or not account was taken of larger male brain size.[11] A study in 2006 using thin slice MRI showed no difference in thickness of the corpus when accounting for the size of the subject.[14] Physiologic imaging[edit] The ability to evaluate the form and function of the human mind has undergone almost exponential growth and a paradigm shift in recent years. Magnetic resonance imaging, for example, is now being used to analyze physiology in addition to anatomy. Using diffusion tensor sequences on MRI machines, the rate that molecules diffuse in and out of a specific area of tissue, directionality or anisotropy, and rates of metabolism can be measured. These sequences have found consistent sex differences in human corpus callosal morphology and microstructure.[which?][15][16][17] Morphometric analysis has also been used to study specific 3-dimensional mathematical relationships with MRIs, and have found consistent and statistically significant differences across genders.[18][19] Specific algorithms have found significant gender differences in over 70% of cases in one review.[20] Gender identity disorder[edit] Research has been done on the shape of the corpus callosum in those with gender identity disorder. Researchers were able to demonstrate that the shape dimorphism of the corpus callosum at birth in biological males who self-identified as female was actually reversed, and that the same held true for biological females who self-identified as male. The publishers of this article argued that the shape of the corpus callosum defined the mental sex of individuals over their physical sex.[20] The relationship between the corpus callosum and gender remains an active subject of debate in the scientific and lay community. Other correlations[edit] The front portion of the corpus callosum has been reported to be significantly larger in musicians than non-musicians, [21] and to be 0.75 square centimeters [22] or 11% larger in left-handed and ambidextrous people than right-handed people.[22][23] This difference is evident in the anterior and posterior regions of the corpus callosum but not in the splenium.[22] Other magnetic resonance morphometric study showed that corpus callosum size correlates positively with verbal memory capacity and semantic coding test performance.[24] Research has shown that children with dyslexia tend to have smaller and less developed corpus callosums than their non-dyslexic counterparts.[25][26] Musical training has shown to increase plasticity of the corpus callosum during a sensitive period of time in development. The implications are an increased coordination of hands, differences in white matter structure, and amplification of plasticity in motor and auditory scaffolding which would serve to aid in future musical training. The study found children who had begun musical training before the age of six (minimum 15 months of training) had an increased volume of their corpus callosum and adults who had begun musical training before the age of 11 also had increased bi-manual coordination. [27] Electroencephalography is used to find the source of electrical activity causing a seizure as part of the surgical evaluation for a corpus callosotomy. The symptoms of refractory epilepsy can be reduced by cutting the corpus callosum in an operation known as a corpus callosotomy.[28] This is usually reserved for cases in which complex or grand mal seizures are produced by an epileptogenic focus on one side of the brain, causing an interhemispheric electrical storm. The work up for this procedure involves an electroencephalogram, MRI, PET scan, and evaluation by a specialized neurologist, neurosurgeon, psychiatrist, and neuroradiologist before surgery can be considered.[29] Brain split procedure[edit] The cerebral cortex is divided into two hemispheres and is connected by the corpus callosum. A procedure that helps patients to alleviate the severity of seizures is called split brain procedure. The result is that a seizure that starts in one hemisphere is isolated in that hemisphere since there is no longer a connection to the other side. However, this procedure is dangerous and risky. Additional images[edit] 1. ^ a b Caminiti, Roberto; Ghaziri, Hassan; Galuske, Ralf; Hof, Patrick R.; Innocenti, Giorgio M. (2009). "Evolution amplified processing with temporally dispersed slow neuronal connectivity in primates". Proceedings of the National Academy of Sciences 106 (46): 19551–6. Bibcode:2009PNAS..10619551C. doi:10.1073/pnas.0907655106. JSTOR 25593230. PMC 2770441. PMID 19875694.  2. ^ Hofer, Sabine; Frahm, Jens (2006). "Topography of the human corpus callosum revisited—Comprehensive fiber tractography using diffusion tensor magnetic resonance imaging". NeuroImage 32 (3): 989–94. doi:10.1016/j.neuroimage.2006.05.044. PMID 16854598.  3. ^ Keeler, Clyde E. (1933). "Absence of the Corpus callosum as a Mendelizing Character in the House Mouse". Proceedings of the National Academy of Sciences of the United States of America 19 (6): 609–11. Bibcode:1933PNAS...19..609K. doi:10.1073/pnas.19.6.609. JSTOR 86284. PMC 1086100. PMID 16587795.  4. ^ Sarnat, Harvey B., and Paolo Curatolo (2007). Malformations of the Nervous System: Handbook of Clinical Neurology, p. 68 5. ^ Ashwell, Ken (2010). The Neurobiology of Australian Marsupials: Brain Evolution in the Other Mammalian Radiation, p. 50 6. ^ Armati, Patricia J., Chris R. Dickman, and Ian D. Hume (2006). Marsupials, p. 175 7. ^ Butler, Ann B., and William Hodos (2005). Comparative Vertebrate Neuroanatomy: Evolution and Adaptation, p. 361 8. ^ Morris, H., & Schaeffer, J. P. (1953). The Nervous system-The Brain or Encephalon. Human anatomy; a complete systematic treatise. (11th ed., pp. 920–921, 964–965). New York: Blakiston. 9. ^ "NINDS Agenesis of the Corpus Callosum Information Page: NINDS". Retrieved Aug. 30, 2011.  10. ^ "Autism May Involve A Lack Of Connections And Coordination In Separate Areas Of The Brain, Researchers Find". Medical News Today.  11. ^ a b Bishop, Katherine M.; Wahlsten, Douglas (1997). "Sex Differences in the Human Corpus Callosum: Myth or Reality?". Neuroscience & Biobehavioral Reviews 21 (5): 581–601. doi:10.1016/S0149-7634(96)00049-8. PMID 9353793.  12. ^ Delacoste-Utamsing, C; Holloway, R. (1982). "Sexual dimorphism in the human corpus callosum". Science 216 (4553): 1431–2. Bibcode:1982Sci...216.1431D. doi:10.1126/science.7089533. PMID 7089533.  13. ^ C Gorman (20 January 1992). "Sizing up the sexes". Time: 36–43.  14. ^ Luders, Eileen; Narr, Katherine L.; Zaidel, Eran; Thompson, Paul M.; Toga, Arthur W. (2006). "Gender effects on callosal thickness in scaled and unscaled space". NeuroReport 17 (11): 1103–6. doi:10.1097/ PMID 16837835.  15. ^ Dubb, Abraham; Gur, Ruben; Avants, Brian; Gee, James (2003). "Characterization of sexual dimorphism in the human corpus callosum". NeuroImage 20 (1): 512–9. doi:10.1016/S1053-8119(03)00313-6. PMID 14527611.  16. ^ Westerhausen, René; Kreuder, Frank; Sequeira, Sarah Dos Santos; Walter, Christof; Woerner, Wolfgang; Wittling, Ralf Arne; Schweiger, Elisabeth; Wittling, Werner (2004). "Effects of handedness and gender on macro- and microstructure of the corpus callosum and its subregions: A combined high-resolution and diffusion-tensor MRI study". Cognitive Brain Research 21 (3): 418–26. doi:10.1016/j.cogbrainres.2004.07.002. PMID 15511657.  17. ^ Shin, Yong-Wook; Jin Kim, Dae; Hyon Ha, Tae; Park, Hae-Jeong; Moon, Won-Jin; Chul Chung, Eun; Min Lee, Jong; Young Kim, In et al. (2005). "Sex differences in the human corpus callosum: Diffusion tensor imaging study". NeuroReport 16 (8): 795–8. doi:10.1097/00001756-200505310-00003. PMID 15891572.  18. ^ Kontos, Despina; Megalooikonomou, Vasileios; Gee, James C. (2009). "Morphometric analysis of brain images with reduced number of statistical tests: A study on the gender-related differentiation of the corpus callosum". Artificial Intelligence in Medicine 47 (1): 75–86. doi:10.1016/j.artmed.2009.05.007. PMC 2732126. PMID 19559582.  19. ^ Spasojevic, Goran; Stojanovic, Zlatan; Suscevic, Dusan; Malobabic, Slobodan (2006). "Sexual dimorphism of the human corpus callosum: Digital morphometric study". Vojnosanitetski pregled 63 (11): 933. doi:10.2298/VSP0611933S.  20. ^ a b Yokota, Y.; Kawamura, Y.; Kameya, Y. (2005). "Callosal Shapes at the Midsagittal Plane: MRI Differences of Normal Males, Normal Females, and GID". 2005 IEEE Engineering in Medicine and Biology 27th Annual Conference. p. 3055. doi:10.1109/IEMBS.2005.1617119. ISBN 0-7803-8741-4.  21. ^ Levitin, Daniel J. "This is Your Brain on Music", ' 22. ^ a b c Witelson, S. (1985). "The brain connection: The corpus callosum is larger in left-handers". Science 229 (4714): 665–8. Bibcode:1985Sci...229..665W. doi:10.1126/science.4023705. PMID 4023705.  23. ^ Driesen, Naomi R.; Raz, Naftali (1995). "The influence of sex, age, and handedness on corpus callosum morphology: A meta-analysis". Psychobiology 23 (3): 240–7.  24. ^ Kozlovskiy, S.A.; Vartanov, A.V.; Pyasik, M.M.; Nikonova, E.Y. (2012). "Functional role of corpus callosum regions in human memory functioning". International Journal of Psychophysiology 85 (3): 396–7. doi:10.1016/j.ijpsycho.2012.07.092.  25. ^ Hynd, G. W.; Hall, J.; Novey, E. S.; Eliopulos, D.; Black, K.; Gonzalez, J. J.; Edmonds, J. E.; Riccio, C. et al. (1995). "Dyslexia and Corpus Callosum Morphology". Archives of Neurology 52 (1): 32–8. doi:10.1001/archneur.1995.00540250036010. PMID 7826273.  26. ^ Von Plessen, K; Lundervold, A; Duta, N; Heiervang, E; Klauschen, F; Smievoll, AI; Ersland, L; Hugdahl, K (2002). "Less developed corpus callosum in dyslexic subjects—a structural MRI study". Neuropsychologia 40 (7): 1035–44. doi:10.1016/S0028-3932(01)00143-9. PMID 11900755.  27. ^ Steele, C. J., Bailey, J. A., Zatorre, R. J. , & Penhune, V. B. (2013), Early musical training and white matter plasticity in the corpus callosum: Evidence for a sensitive period. Journal of Neuroscience, 33(3), 1282-1290. 28. ^ Clarke, Dave F.; Wheless, James W.; Chacon, Monica M.; Breier, Joshua; Koenig, Mary-Kay; McManis, Mark; Castillo, Edward; Baumgartner, James E. (2007). "Corpus callosotomy: A palliative therapeutic technique may help identify resectable epileptogenic foci". Seizure 16 (6): 545–53. doi:10.1016/j.seizure.2007.04.004. PMID 17521926.  29. ^ "WebMd Corpus Callotomy". Web MD. July 18, 2010. Retrieved July 18, 2010.  External links[edit]
http://en.wikipedia.org/wiki/Corpus_collosum
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Giordano Bruno (crater) From Wikipedia, the free encyclopedia Jump to: navigation, search Giordano Bruno (crater) Wfm giordano bruno.jpg Giordano Bruno. NASA photo. Coordinates 35°54′N 102°48′E / 35.9°N 102.8°E / 35.9; 102.8Coordinates: 35°54′N 102°48′E / 35.9°N 102.8°E / 35.9; 102.8 Diameter 22 km Depth Unknown Colongitude 258° at sunrise Eponym Giordano Bruno Oblique view from Apollo 11 showing the extent of the rays. Mare Marginis is in the right foreground. This feature was named after the Italian philosopher Giordano Bruno. In 1976, the geologist Jack B. Hartung proposed that this described the formation of the crater Giordano Bruno.[3] Modern theories predict that a (conjectural) asteroid or comet impact on the Moon would cause a plume of molten matter rising up from the surface, which is consistent with the monks' description. In addition, the location recorded fits in well with the crater's location. Additional evidence of Giordano Bruno's youth is its spectacular ray system: because micrometeorites constantly rain down, they kick up enough dust to quickly (in geological terms) erode a ray system,[4] so it can be reasonably hypothesized that Giordano Bruno was formed during the span of human history, perhaps in June 1178. However, the question of the crater's age is not that simple. The impact creating the 22-km-wide crater would have kicked up 10 million tons of debris, triggering a week-long, blizzard-like meteor storm on Earth – yet no accounts of such a noteworthy storm of unprecedented intensity are found in any known historical records, including the European, Chinese, Arabic, Japanese and Korean astronomical archives.[5] This discrepancy is a major objection to the theory that Giordano Bruno was formed at that time.[6] 1. ^ Sincell, Mark (May 7, 2001). "Nothing But Moonshine". American Association for the Advancement of Science. Retrieved March 13, 2013.  2. ^ The Cosmic Winter, Clube and Napier. Blackwell Publishing, First Edition (May 1990) 3. ^ Jack B., Hartung (1976). "Was the Formation of a 20-km Diameter Impact Crater on the Moon Observed on June 18, 1178?". Meteoritics 11 (3): 187. Bibcode:1976Metic..11..187H.  4. ^ Camale, O.; Mulholland, J. D. (1978). "Lunar Crater Giordano Bruno: A.D. 1178 Impact Observations Consistent with Laser Ranging Results". Science 199 (4331): 875–87. Bibcode:1978Sci...199..875C. doi:10.1126/science.199.4331.875. PMID 17757584.  5. ^ Kettlewell, Jo (1 May 2001). "Historic lunar impact questioned". BBC. Retrieved 8 April 2012.  6. ^ Stiles, Lori (April 20, 2001). "What Medieval Witnesses Saw Was Not Big Lunar Impact, Grad Student Says". University of Arizona. Retrieved March 13, 2013.  7. ^ "The Mysterious Case of Crater Giordano Bruno". NASA. Retrieved 8 April 2012.
http://en.wikipedia.org/wiki/Giordano_Bruno_(crater)
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You are viewing this Genus as classified by: IUCN threat status: Not evaluated Brief Summary Read full entry The polyps of Pocillopora corals are hermaphrodite; they each possess four sets of male and four sets of female gonads (2). Pocillopora can reproduce asexually as well as sexually. Unlike many corals, the coral larvae develop inside the polyps rather than in the water column. When the mature larvae are released into the water, the larvae can remain free-swimming for several weeks before settling on the substrate. They can even become partly polyp-like during this period, enabling feeding to occur before settling and commencing skeleton formation (2). Pocillopora can also successfully reproduce asexually via fragmentation (5). Pocillopora corals are hermatypic corals, and therefore have microscopic algae (zooxanthellae) living within their tissues. Through photosynthesis, these symbiotic algae produce energy-rich molecules that the coral polyps can use as nutrition (2). In return, the coral provides the zooxanthellae with protection, and access to sunlight. The wide geographic distribution of Pocillopora corals is probably due to rafting, whereby small colonies attach to floating objects, such as pumice, where they can travel great distance to remote places (3). The polyps can also obtain nutrition by capturing tiny prey using their tentacles. © Wildscreen Source: ARKive Belongs to 0 communities This taxon hasn't been featured in any communities yet. Learn more about Communities
http://eol.org/pages/23297/hierarchy_entries/46223847/overview
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Re: Release plans? Bits from the RMs? Christian Perrier schrieb: > So, what's the status now? Can't answer for the release team, but it seems to me, that everyone is waiting for the outcome of GR 2008/vote_003 [1]... But I would appreciate an "official Bits from" mail, too. 1: http://www.debian.org/vote/2008/vote_003 Best regards, Reply to:
http://lists.debian.org/debian-devel/2008/12/msg00486.html
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Switch to Desktop Site Rather Than Mass Killing, Serbs Are Forcing Rebels to Care for Refugees Recent mass-grave claims and 'ethnic cleansing' charges are played down by West. About these ads The body of Xhelal Ejudi, an ethnic Albanian, is buried beneath a heap of garbage and marked by a sun-bleached wooden stake. The body of Eshref Shehu, killed three weeks ago, lies under cans, flattened plastic bottles, and an old sneaker. The crude graveyard is tucked in the hills just outside Orahovac, where Serbian forces last month battled with ethnic Albanian rebels seeking independence for Kosovo. There are 25 stakes, but it is unclear exactly what lies below ground. Serbian authorities confirmed that they collected 58 bodies after the fighting in Orahovac. They held most of them unclaimed for a week in the nearby city of Prizren and buried the remainder between July 20 and Aug. 3. Reports of the trash-dump graveyard, and of some 200,000 displaced persons, have sent a wave of fear through Kosovo. "This is like Bosnia, with ethnic cleansing, house-burning, and mass graves," says Sylejman Canta, a grape farmer from Orahovac who last week watched from a hill as a bulldozer dug the graveyard. Mr. Canta was one of the few who had returned after having fled the fighting. But international officials have made distinctions between what happened in Bosnia during its 1992-95 civil war and what is taking place in Serbia's independence-seeking southern province. More than 400 people have died in Kosovo since fighting erupted Feb. 28, but the international community has stopped short of using force to stop the violence. European Union monitors visited Orahovac Aug. 5 and said there was no evidence of a "mass grave." Unlike in Bosnia, efforts had been made to identify the dead. And during a recent interview, a senior Western diplomat was careful not to use the phrase "ethnic cleansing," a term coined in Bosnia when ethnic groups were forced out and replaced with other nationalities in an effort to create ethnically pure regions. "You bet it's disturbing," says the diplomat, who spoke on condition of anonymity. But "I don't think the [Serbian authorities] are looking to replace the Albanian people with Serbian people." Page:   1   |   2
http://m.csmonitor.com/1998/0807/080798.intl.intl.3.html
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Subject: Support for Lite-On Communications NIC? From: Paul Goyette <> List: current-users Date: 09/03/2001 17:53:46 weeks ago. Any idea what it might take to support this beast? If too much hassle, I can just replace it with something more "mainstream", but I just love using free stuff! | Network Engineer | BCD7 5301 9513 58A6 0DBC | | | & World Cruiser | 91EB ADB1 A280 3B79 9221 | |
http://mail-index.netbsd.org/current-users/2001/09/03/0017.html
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Port-arm archive Re: TS-7200: time sync issues >: I'm sorry if this wasn't clear ... but the problem seems to be within >: the settimeofday() (or perhaps clock_settime()) function. Once ntpd >: gets "lucky" and gets the clock within 128ms, it's happy. Right now >: my TS-7200 box has been up for over a day without any time steps, and >: ntptime shows a frequency of -51 ppm. >Why must this be the case? ntpd doesn't even use these functions. Respectfully ... you are wrong (about ntpd not using these functions). When the time is stepped, ntpd calls step_systime(). step_systime() calls ntp_set_tod(). ntp_set_tod() calls clock_settime() or settimeofday(). I am of course speaking about the ntpd that ships with NetBSD. >You'd get the same problem if your frequency was wrong, or if you were >missing clock interrupts so that time would run slow. Yeah .... but that still doesn't explain why it syncs up fine once it gets within the offset threshold for frequency adjustment. >What happens if you do two ntpdates in a row? ts7200# ntpdate timeserver 9 Dec 23:51:48 ntpdate[587]: step time server offset 0.620005 sec ts7200# !! ntpdate timeserver 9 Dec 23:51:54 ntpdate[554]: step time server offset 0.723242 sec ts7200# !! ntpdate timeserver 9 Dec 23:51:55 ntpdate[564]: adjust time server offset 0.332673 sec ts7200# !! ntpdate timeserver 9 Dec 23:51:57 ntpdate[41]: adjust time server offset 0.326644 sec >Also, you are reading the logs wrong. ntpd does a poll every 1024 I didn't get into my setup at all .... but in this particular configuration my TS-7200 is a broadcast ntp client, and that broadcast happens ... every 64 seconds? Something like that. I don't think that is an issue, as other systems using the same broadcast server don't have any problems. Simon Burge <simonb%netbsd.org@localhost> >I'd guess some catastrophic arithmetic error in the time counter code >(see other examples of wrong mask earlier in this thread) or clock >interrupts being blocked for too long. >With ntpd disabled, what does something like: Yeah, that shows a relatively small amount of drift, nothing like above: 9 Dec 23:58:16 ntpdate[494]: adjust time server offset 0.301362 sec 9 Dec 23:58:17 ntpdate[756]: adjust time server offset 0.301358 sec 9 Dec 23:58:19 ntpdate[780]: adjust time server offset 0.301344 sec 9 Dec 23:58:20 ntpdate[762]: adjust time server offset 0.301336 sec Really, you can easily force the problem no matter what the offset is by doing "ntpdate -b". E.g.: client# ntpdate -q timeserver 10 Dec 00:06:06 ntpdate[920]: adjust time server offset -0.039474 ntpdate -q timeserver server, stratum 3, offset -0.033536, delay 0.02690 10 Dec 00:06:37 ntpdate[911]: adjust time server offset -0.033536 client# !! ntpdate -q timeserver server, stratum 3, offset -0.033144, delay 0.02689 10 Dec 00:06:39 ntpdate[884]: adjust time server offset -0.033144 se client# ntpdate -b timeserver 10 Dec 00:07:06 ntpdate[907]: step time server offset -0.028554 sec client# ntpdate -q timeserver server, stratum 3, offset 0.786812, delay 0.02689 10 Dec 00:07:13 ntpdate[361]: step time server offset 0.786812 sec I'm not trying to be an obstinate bastard, honest. I really do appreciate the help. I just can't convince myself that this is a frequency problem. My best guesses are that clock interrupts are blocked for too long when setting the TOD clock, or there is some strange arithmatic error when the time is set. The reason I don't think it's a frequency problem is that I _did_ have a frequency problem back on my Net4501. That turned out to be a particular issue with the ElanSC having a slightly different clock than the standard PC one. In that case ntpd would never sync up and just continually stepped all the time. Like I said, once the TS-7200 gets the clock within 128ms, ntpd switches to only doing frequency adjustments and then there are no further time steps. Home | Main Index | Thread Index | Old Index
http://mail-index.netbsd.org/port-arm/2008/12/10/msg000521.html
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website hit counter Short Bits: Digital Copy, tru2way, Big Media - Chris Lanier Short Bits: Digital Copy, tru2way, Big Media Remember just last month when I said “I’d like to see companies embrace the fact that DVD is still the mainstream format?”  Based on a story in CED from this past week studios are starting to realize that’s the key, with one Warner exec saying “….64 percent of consumers said having a digital file gives better value.”  This story was about including protected digital copies of films on DVDs (Example) which I think is a great idea and needs to happen much more often (on all DVDs).  Now let’s also see it work the opposite way too, if I buy a digital download allow me to get the physical DVD at a discounted price (or free? Yeah right) I know I haven’t covered tru2way much yet, but that’s because there isn’t much to say.  Quickly, tru2way is CableLabs basically renaming the CableCARD 2.0/OCAP platform.  Of course a large majority of the media doesn’t understand any part of it; CNET even asked if tru2way can succeed where CableCARD failed.  Just so we are clear, tru2way is a platform for CableCARDs.  It’s now a two-way platform instead of one-way like all previous devices.  It will require use of the exact same CableCARDs (which are all two-way).  MegaZone did a good job explaining it, yet CNET didn’t retract the article or edit it despite the fact it is 100% incorrect.  Two-way CableCARD for Media Center isn’t likely to appear until Windows 7. Speaking of CNET (now owned by CBS), anyone else find it ironic that big media conglomerates have purchased these smaller outlets which still post on things like breaking copy protection on DVDs?  Hey CBS, if your new media outlets are going to report on breaking copy protection, let’s just skip the formalities and disable things like CGMS-A on Showtime, AACS on CBS Blu-ray Discs, CSS on DVDs, etc. Published Sat, Jun 7 2008 13:52 by chrisl # re: Short Bits: Digital Copy, tru2way, Big Media Chris, I've been trying to find an answer for this.  What happens to CGMS-A when digital becomes the standard, and all analog tv stops broadcasting? Saturday, June 07, 2008 4:50 PM by Jeffrey You can add CGMS-A on output from an STB.  Since it is only supposed to be used on cable/sat, it isn't an issue to add it during the output (S-Video, etc). Saturday, June 07, 2008 5:17 PM by chrisl I'm not following your point on tru2way... sure current cablecard (the cards) are 2 way capable but none of the current cablecard tuners are 2 way devices. If you are trying to make the distinction between the functionality of the tuner and the card, so be it, but CNET saying cablecard has failed is an accurate assesment since current cablecard tuners are one-way.  So, to-date, cablecards have been a failure. Well... current cablecard "tuners" have failed... because the cable companies wanted them to (since they cut off existing sources of revenue). It's still early but tru2way "appears" to actually have the backing of the cable companies because it allows them to retain their existing revenue streams (ondemand, SDV, etc.) and allows them to add new functionality (interactive content, integration with other media distribution services that may be IP based, etc.). Sunday, June 08, 2008 3:43 PM by Al Al: I think you need to go back and read the CNET article.  They clearly don't understand what tru2way is, which is the point I'm making.  Case-in-point, they say flat out "...that's effectively what Tru2way is: the next-gen CableCard, without the physical card."  What?  tru2way is not CableCARD without the CableCARD. Cable companies still don't like CableCARD because they still don't get to charge you $15/month for their STBs if you pick another device.  It does have the backing of a few major CE companies, which is very important, but that's a big difference from the cable companies liking the change. Will tru2way be more of a success than current CableCARD products?  You bet!  Is this the development that does away with STBs like many sites are saying right now?  No.  It is sure an upgrade from v1 though. Sunday, June 08, 2008 4:05 PM by chrisl Ahhh... gotcha... you are right I didn't read the article and by reading your post I didn't understand what your issue was with CNET's article.  Thanks for clarifying. The cable companies don't care much about the box rental fees.  If they did they would just charge more for the cablecard rental.  They care about the fact that they lose ondemand revenue, payperview event revenue and the fact that it prevents their move to SDV. Monday, June 09, 2008 8:25 PM by Al
http://msmvps.com/blogs/chrisl/archive/2008/06/07/1632637.aspx
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Effort to rate Oklahoma judges is a far cry from judicial bullying The Oklahoman Editorial Published: June 10, 2012 The chambers' plan would give non-lawyers at least some information before casting a ballot. The rating plan is an informational campaign, just like any other in politics. Is there bias in the chambers' rating system? Sure. Just like there's bias in any report evaluating lawmakers. And just like there's bias in campaign contributions: Attorneys and businesses don't give money equally to all candidates in all races. Furthermore, citizens who don't agree with the chambers' agenda are free to ignore their rankings — or even determine candidate selection based on who the chambers rank as being the worst. Too often, Oklahoma citizens must vote on judicial races in an information vacuum. The chambers' efforts would fill part of that void. We hope the information provided is relevant, credible and in context. The chambers' ratings system must be a serious and deliberative effort that doesn't criticize judges for merely upholding the law as it's written. Otherwise, they shouldn't bother with the project. Whether the public is better served by having direct election of judges instead of making them appointees is a debate worth having. But to claim judicial bullying is under way just because a group wants to increase public awareness during campaign season is nonsense. | | Mortgage Rates Hit 2.75% natural gas Facts Liquefied Natural Gas: A Clean, Safe, Reliable Fuel. Trending Now
http://newsok.com/effort-to-rate-oklahoma-judges-is-a-far-cry-from-judicial-bullying/article/3682596/?page=2
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CBS2-Header-Logo WFAN 1010WINS WCBS tiny WLNYLogo Brenda Simmons A Long Island family wants to tear down a house that may have once been owned by freed slave Pyrrhus Concer. (Credit CBS 2) Demolition Plans Delayed For Supposedly Historic Hamptons Home
http://newyork.cbslocal.com/tag/brenda-simmons/
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Perdido 03 Perdido 03 Saturday, September 1, 2012 Prop 37 Proposition 37 in California would require companies to label foods that are "made from plants or animals with genetic material changed in specified ways." Companies in California will no longer be able to call foods made with GMO material "natural," as they do now. This is a pretty big thing and of course the big companies are providing funding to fight Prop 37 from passing because they fear once California forces labeling of GMO material, the rest of the nation will as well. Here you can see the companies putting up money to fight Prop 37. It's the usual conglomerates, but what you may not know is that many of these conglomerates own the "natural" and "organic" companies. Kashi, for example, which uses GMO material in almost all of its products (but labels them "natural" and prices them higher accordingly) is owned by Kelloggs. While Kashi has not donated any money against Prop 37, its parent company Kelloggs has donated over $630,000 If Prop 37 passes, Kashi, the "natural" food company, will have to label the crap its selling as the genetically modified shit it is instead of being able to market itself as some healthier alternative to conventional processed foods. You can imagine how a change in labeling law will affect dishonest companies like Kashi that sell "natural" foods to consumers that are anything but. You can see a chart of all the "natural" and "organic" companies and who owns them here. Just as in education, never believe the hype or the p.r. in the food world. Follow the money instead. "Organic" and "natural" companies owned by Cargill, ConAgra, Dean, General Mills, Kelloggs et al. are selling you stuff that is anything but organic or healthy. Prop 37 will make these shysters and con artists own up to their sleight of hand. Here's hoping Prop 37 passes. Oh, and if you have any Kashi in the pantry, throw that shit away. 1 comment: 1. Gates/Microsoft Foundation + Monsanto/GMO Foods = Privatized gene pools, food, water, schools and eventually the air we breathe. The keystone linking Gates (who has never been a technological innovator, but rather an obsessive monopolist) and Monsanto is "intellectual property rights," i.e. the state-sanctioned right to monetize and control the choke points and toll booths of every social transaction, and ultimately every bodily function and need.
http://perdidostreetschool.blogspot.com/2012/09/prop-37.html
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Search tips Search criteria Results 1-25 (886513) Clipboard (0) Related Articles 1.  Complement C1s activation in degenerating articular cartilage of rheumatoid arthritis patients: immunohistochemical studies with an active form specific antibody  Annals of the Rheumatic Diseases  1999;58(3):175-181. OBJECTIVE—The first complement component C1s was reported to have novel functions to degrade matrix components, besides its activities in the classic complement pathway. This study explores participation of C1s in articular cartilage degradation in rheumatoid arthritis (RA).
METHODS—Normal articular cartilage (n=6) and cartilage obtained from joints with RA (n=15) and osteoarthritis (OA, n=10) were immunostained using anti-C1s monoclonal antibodies PG11, which recognises both active and inactive C1s, and M241, which is specifically reactive to activated C1s. The effects of inflammatory cytokines on C1s production by human articular chondrocytes were also examined by sandwich ELISA.
RESULTS—In normal articular cartilage, C1s was negative in staining with both PG11 and M241. In contrast, degenerating cartilage of RA was stained with PG11 (14 of 15 cases), and in most of the cases (13 of 15 cases) C1s was activated as revealed by M241 staining. In OA, C1s staining was restricted in severely degrading part of cartilage (5 of 10 cases), and even in that part C1s was not activated. In addition, C1s production by chondrocytes in vitro was increased by an inflammatory cytokine, tumour necrosis factor α.
CONCLUSION—These results suggest that C1s activated in degenerative cartilage matrix of RA but not in that of OA. C1s is thought to participate in the pathogenesis of RA through its collagenolytic activity in addition to the role in the classic cascade.

 Keywords: complement C1s; articular cartilage; rheumatoid arthritis PMCID: PMC1752845  PMID: 10364916 2.  Bony island within the articular cartilage of the knee in a child: a rare condition for early osteoarthritis  Orthopedic Reviews  2011;3(1):e5. Articular cartilage is a specific type of connective tissue composed of hydrated proteoglycans within a matrix of collagen fibrils. In the elderly population, it shows degenerative changes that may results in osteoarthritis. The more severe form of osteoarthritis occasionally demonstrates bone formation within the cartilage, which is designated as a bony protuberance, however, such lesions are rare in children. This report presents the case of a 10-year-old boy with a bony protuberance within the articular cartilage of the knee. The patient initially complained of knee pain and he subsequently developed flexion contracture. Radiological and arthroscopic examinations revealed a bony protuberance in the articular cartilage and degenerative changes of the cartilage above it. He was successfully treated by the removal of the bony protuberance and osteochondral grafting. The bony protuberance may have caused cartilage degradation since the thickness of the cartilage above it was thinner than that around the lesion. The bony protuberance within the articular cartilage formed in the younger population may be a possible cause of osteoarthritis. This case is a noteworthy with regard to the pathogenesis of osteoarthritis. PMCID: PMC3143997  PMID: 21808717 bone protuberance; articular cartilage; osteoarthritis; child. Orthopedic Reviews  2011;3(1):e7. PMCID: PMC3144001  PMID: 21808719 bone protuberance; articular cartilage; osteoarthritis; child. Materials and methods PMCID: PMC3163794  PMID: 21863259 Simvastatin; Anterior cruciate ligament transection; Knee osteoarthritis; Matrix metalloproteinase-3 5.  Cartilage homeostasis in health and rheumatic diseases  As the cellular component of articular cartilage, chondrocytes are responsible for maintaining in a low-turnover state the unique composition and organization of the matrix that was determined during embryonic and postnatal development. In joint diseases, cartilage homeostasis is disrupted by mechanisms that are driven by combinations of biological mediators that vary according to the disease process, including contributions from other joint tissues. In osteoarthritis (OA), biomechanical stimuli predominate with up-regulation of both catabolic and anabolic cytokines and recapitulation of developmental phenotypes, whereas in rheumatoid arthritis (RA), inflammation and catabolism drive cartilage loss. In vitro studies in chondrocytes have elucidated signaling pathways and transcription factors that orchestrate specific functions that promote cartilage damage in both OA and RA. Thus, understanding how the adult articular chondrocyte functions within its unique environment will aid in the development of rational strategies to protect cartilage from damage resulting from joint disease. This review will cover current knowledge about the specific cellular and biochemical mechanisms that regulate cartilage homeostasis and pathology. PMCID: PMC2714092  PMID: 19519926 Articular cartilage degeneration in osteoarthritis has been linked to abnormal mechanical stresses that are known to cause chondrocyte apoptosis and metabolic derangement in in vitro models. Evidence implicating oxidative damage as the immediate cause of these harmful effects suggests that the anti-oxidant defenses of chondrocytes might influence their tolerance for mechanical injury. Based on evidence that anti-oxidant defenses in many cell types are stimulated by moderate oxidant exposure, we hypothesized that oxidant pre-conditioning would reduce acute chondrocyte death and proteoglycan depletion in cartilage explants after exposure to abnormal mechanical stresses. Porcine cartilage explants were treated every 48 hours with tert-butyl hydrogen peroxide (tBHP) at non-lethal concentrations (25, 100, 250, 500 µM) for a varying number of times (1, 2 or 4) prior to a bout of unconfined axial compression (5 MPa, 1 Hz, 1800 cycles). When compared with untreated controls, tBHP had significant positive effects on post-compression viability, lactate production, and proteoglycan losses. Overall, the most effective regime was 100 µM tBHP applied 4 times. RNA analysis revealed significant effects of 100 µM tBHP on gene expression. Catalase, hypoxia-inducible factor-1alpha (HIF-1α), and glyceraldehyde 6-phosphate dehydrogenase (GAPDH) were significantly increased relative to untreated controls in explants treated 4 times with 100 µM tBHP, a regime that also resulted in a significant decrease in matrix metalloproteinase-3 (MMP-3) expression. These findings demonstrate that repeated exposure of cartilage to sub-lethal concentrations of peroxide can moderate the acute effects of mechanical stress, a conclusion supported by evidence of peroxide-induced changes in gene expression that could render chondrocytes more resistant to oxidative damage. PMCID: PMC3708667  PMID: 20058262 Cartilage; mechanical stress; oxidant 7.  Mechanisms of disruption of the articular cartilage surface in inflammation. Neutrophil elastase increases availability of collagen type II epitopes for binding with antibody on the surface of articular cartilage.  Journal of Clinical Investigation  1991;87(5):1531-1536. We recently observed that specific antibodies to type II collagen do not bind in appreciable amounts to the intact surface of articular cartilage, whereas antibodies to the minor collagen types V, VI, and IX do. These results suggest that the outermost cartilage surface layer prevented interaction of the antibodies with the major collagen type in articular cartilage. The present studies were designed to investigate the pathogenic mechanisms involved in the disruption of the cartilage surface layer in inflammatory arthritis. Articular cartilage obtained from rabbits undergoing acute antigen-induced arthritis of 72 h duration showed a significant increase in binding of anti-type II antibody to cartilage surfaces compared with normal control cartilage (P less than 0.01). Augmentation of anti-type II binding was also observed upon in vitro incubation of bovine articular slices or intact rabbit patellar cartilage for 1 h with human polymorphonuclear neutrophils (PMN), PMN lysates, or purified human PMN elastase. This increase was not inhibited by sodium azide, nor was it enhanced by incubation of cartilage with the strong oxidant hypochlorous acid. Chondrocyte-mediated matrix proteoglycan degradation in cartilage explants cultured in the presence of cytokines failed to increase antibody binding appreciably. The augmentation in antibody binding seen with PMN lysates was inhibited by the nonspecific serine-esterase inhibitor PMSF, but not by the divalent metal chelator EDTA. The elastase-specific inhibitor AAPVCMK also inhibited most of the PMN-induced increase in antibody binding, whereas the cathepsin G-specific inhibitor GLPCMK was much less effective. Incubation of intact cartilage with purified human PMN elastase indicated that this serine esterase could account for the increase in anti-type II collagen antibody binding to intact cartilage surfaces. These studies suggest that in an inflammatory response, PMN-derived elastase degrades the outer layer of articular cartilage, exposing epitopes on type II collagen. They also help clarify the pathogenic mechanisms involved in early articular cartilage damage in inflammatory joint diseases. PMCID: PMC295233  PMID: 1708782 8.  Cartilage healing: A review with emphasis on the equine model  The Canadian Veterinary Journal  1990;31(8):565-572. Articular cartilage is a remarkably resilient tissue capable of withstanding considerable stress and repeated loading. Since this tissue has no blood vessels, nerve elements, or lymphatics, it is not surprising that it has a limited capacity for repair when damaged. In the horse, cartilage damage occurs as an occupational hazard. Furthermore, developmental defects such as osteochondrosis can lead to osteochondritis dissecans. Resultant cartilage flaps, fissures, and poorly organized subchondral bone produce disruption of joint surfaces. Veterinarians are often called upon to intervene when damaged cartilage has healed incompletely. Basic understanding of the physiology and repair mechanisms of cartilage is paramount to successfully managing such injuries. This literature review gives a brief overview of recently published clinical and experimental studies on the healing of cartilage. The discussion centers on the equine model. PMCID: PMC1480835  PMID: 17423644 9.  Mesenchymal chondroprogenitor cell origin and therapeutic potential  Mesenchymal progenitor cells, a multipotent adult stem cell population, have the ability to differentiate into cells of connective tissue lineages, including fat, cartilage, bone and muscle, and therefore generate a great deal of interest for their potential use in regenerative medicine. During development, endochondral bone is formed from a template of cartilage that transforms into bone; however, mature articular cartilage remains in the articulating joints, where its principal role is reducing friction and dispersing mechanical load. Articular cartilage is prone to damage from sports injuries or ageing, which regularly progresses to more serious joint disorders, such as osteoarthritis. Osteoarthritis is a degenerative joint disease characterized by the thinning and eventual wearing of articular cartilage, and affects millions of people worldwide. Due to low chondrocyte motility and proliferative rates, and complicated by the absence of blood vessels, cartilage has a limited ability to self-repair. Current pharmaceutical and surgical interventions fail to generate repair tissue with the mechanical and cellular properties of native host cartilage. The long-term success of cartilage repair will therefore depend on regenerative methodologies resulting in the restoration of articular cartilage that closely duplicates the native tissue. For cell-based therapies, the optimal cell source must be readily accessible with easily isolated, abundant cells capable of collagen type II and sulfated proteoglycan production in appropriate proportions. Although a cell source with these therapeutic properties remains elusive, mesenchymal chondroprogenitors retain their expansion capacity with the promise of reproducing the structural or biomechanical properties of healthy articular cartilage. As current knowledge regarding chondroprogenitors is relatively limited, this review will focus on their origin and therapeutic application. PMCID: PMC3092148  PMID: 21371355 10.  New developments in osteoarthritis. Posttraumatic osteoarthritis: pathogenesis and pharmacological treatment options  PMCID: PMC2911903  PMID: 20602810 Arthritis Research & Therapy  2011;13(5):R142. Traumatic joint injury damages cartilage and causes adjacent joint tissues to release inflammatory cytokines, increasing the risk of developing osteoarthritis. The main objective of this study was to determine whether the combined catabolic effects of mechanical injury, tumor necrosis factor alpha (TNFα) and interleukin-6 (IL-6)/soluble IL-6 receptor (sIL-6R) on cartilage could be abolished by short-term treatment with glucocorticoids such as dexamethasone. In an initial dexamethasone-dose-response study, bovine cartilage explants were treated with TNFα and increasing concentrations of dexamethasone. Bovine and human cartilage explants were then subjected to individual and combined treatments with TNFα, IL-6/sIL-6R and injury in the presence or absence of dexamethasone. Treatment effects were assessed by measuring glycosaminoglycans (GAG) release to the medium and synthesis of proteoglycans. Additional experiments tested whether pre-exposure of cartilage to dexamethasone could prevent GAG loss and inhibition of biosynthesis induced by cytokines, and whether post-treatment with dexamethasone could diminish the effects of pre-established cytokine insult. Messenger ribonucleic acid (mRNA) levels for genes involved in cartilage homeostasis (proteases, matrix molecules, cytokines, growth and transcription factors) were measured in explants subjected to combined treatments with injury, TNFα and dexamethasone. To investigate mechanisms associated with dexamethasone regulation of chondrocyte metabolic response, glucocorticoid receptor (GR) antagonist (RU486) and proprotein convertase inhibitor (RVKR-CMK) were used. Dexamethasone dose-dependently inhibited GAG loss and the reduction in biosynthesis caused by TNFα. The combination of mechanical injury, TNFα and IL-6/sIL-6R caused the most severe GAG loss; dexamethasone reduced this GAG loss to control levels in bovine and human cartilage. Additionally, dexamethasone pre-treatment or post-treatment of bovine explants lowered GAG loss and increased proteoglycan synthesis in cartilage explants exposed to TNFα. Dexamethasone did not down-regulate aggrecanase mRNA levels. Post-transcriptional regulation by dexamethasone of other genes associated with responses to injury and cytokines was noted. GR antagonist reversed the effect of dexamethasone on sulfate incorporation. RVKR-CMK significantly reduced GAG loss caused by TNFα + IL-6 + injury. Short-term glucocorticoid treatment effectively abolished the catabolic effects exerted by the combination of pro-inflammatory cytokines and mechanical injury: dexamethasone prevented proteoglycan degradation and restored biosynthesis. Dexamethasone appears to regulate the catabolic response of chondrocytes post-transcriptionally, since the abundance of transcripts encoding aggrecanases was still elevated in the presence of dexamethasone. PMCID: PMC3308070  PMID: 21888631 Osteoarthritis is a disease process of cellular degradation of articular cartilage caused by mechanical loads and inflammatory cytokines. We studied the cellular response in native cartilage subjected to a mechanical load administered simultaneously with an inflammatory cytokine (IL-1), hypothesizing that the combination of load and cytokine would result in accelerated extracellular matrix (ECM) degradation. Mature bovine articular cartilage was loaded for three days (stimulation) with 0.2 and 0.5 MPa stresses, with and without interleukin-1 (IL-1α, 10 ng/ml), followed by three days of no stimulation (recovery). Aggrecan and collagen loss were measured as well as aggrecan cleavage using monoclonal antibodies AF-28 and BC-3 for cleavage by aggrecanases (ADAMTS) and matrix metalloproteinases (MMPs), respectively. Incubation with IL-1 caused aggrecan cleavage by aggrecanases and MMPs during the three days of stimulation. A load of 0.5 MPa inhibited the IL-1-induced aggrecan loss while no inhibition was found for the 0.2 MPa stress. There was no collagen loss during the treatments but upon load and IL-1 removal proteoglycan and collagen loss increased. Load itself under these conditions was found to have no effect when compared to the unloaded controls. A mechanical load of sufficient magnitude can inhibit ECM degradation by chondrocytes when stimulated by IL-1. The molecular mechanisms involved in this process are not clear but probably involve altered mechanochemical signal transduction between the ECM and chondrocyte. PMCID: PMC2818235  PMID: 19747586 Cartilage; Mechanobiology; Load; IL-1; MMPs; ADAMTS 13.  Polymer Mechanics as a Model for Short-Term and Flow-Independent Cartilage Viscoelasticity  Articular cartilage is the load bearing soft tissue that covers the contacting surfaces of long bones in articulating joints. Healthy cartilage allows for smooth joint motion, while damaged cartilage prohibits normal function in debilitating joint diseases such as osteoarthritis. Knowledge of cartilage mechanical function through the progression of osteoarthritis, and in response to innovative regeneration treatments, requires a comprehensive understanding of the molecular nature of interacting extracellular matrix constituents and interstitial fluid. The objectives of this study were therefore to (1) examine the timescale of cartilage stress-relaxation using different mechanistic models and (2) develop and apply a novel (termed “sticky”) polymer mechanics model to cartilage stress-relaxation based on temporary binding of constituent macromolecules. Using data from calf cartilage samples, we found that different models captured distinct timescales of cartilage stress-relaxation: monodisperse polymer reptation best described the first second of relaxation, sticky polymer mechanics best described data from ∼1-100 seconds of relaxation, and a model of inviscid fluid flow through a porous elastic matrix best described data from 100 seconds to equilibrium. Further support for the sticky polymer model was observed using experimental data where cartilage stress-relaxation was measured in either low or high salt concentration. These data suggest that a complete understanding of cartilage mechanics, especially in the short time scales immediately following loading, requires appreciation of both fluid flow and the polymeric behavior of the extracellular matrix. PMCID: PMC3087607  PMID: 21552375 Articular cartilage; osteoarthritis; polymer dynamics; reptation; viscoelasticity; biomechanics Osteoarthritis (OA) is associated with increased levels of reactive nitrogen and oxygen species and pro-inflammatory cytokines, such as interleukin-1 (IL-1). Nitric oxide (NO) can mediate a number of the catabolic effects of IL-1 in articular cartilage. The aims of this study were to determine if OA cartilage shows evidence of DNA damage, and if IL-1 could induce DNA damage in non-OA cartilage by increasing NO or superoxide. Articular chondrocytes were isolated from porcine femoral condyles and embedded in 1.2% alginate. The effects of 24 hrs incubation with IL-1, the nitric oxide synthase 2 (NOS2) selective inhibitor, the free radical scavenger SOD, the NO donor NOC18, or the combined NO and peroxynitrite donor SIN-1 on DNA damage were tested, using the “comet” assay. NO production was measured using the Griess assay. The type of oxidative damage present was assessed using a modified comet assay. OA cartilage had significantly more DNA damage than non-OA cartilage (p < 0.001). IL-1 caused an increase in DNA damage (p < 0.01), which was associated with increased NO production (p < 0.01). Both oxidative DNA strand breaks and base modifications of purines and pyrimidines were observed. IL-1-induced DNA damage was inhibited by a NOS2 inhibitor or by superoxide dismutase (p < 0.01). Furthermore, NOC-18 or SIN-1 caused DNA damage (p < 0.001). Our work shows chondrocytes in osteoarthritic cartilage exhibit DNA damage, and that IL-1 induces DNA damage and reactive oxygen and nitrogen species in non-OA chondrocytes in alginate. PMCID: PMC2430155  PMID: 17945515 15.  Post-translational aging of proteins in osteoarthritic cartilage and synovial fluid as measured by isomerized aspartate  PMCID: PMC2688206  PMID: 19371408 It is currently poorly known how different structural and compositional components in human articular cartilage are related to their specific functional properties at different stages of osteoarthritis (OA). The objective of this study was to characterize the structure-function relationships of articular cartilage obtained from osteoarthritic human hip joints. Articular cartilage samples with their subchondral bone (n = 15) were harvested during hip replacement surgeries from human femoral necks. Stress-relaxation tests, Mankin scoring, spectroscopic and microscopic methods were used to determine the biomechanical properties, OA grade, and the composition and structure of the samples. In order to obtain the mechanical material parameters for the samples, a fibril-reinforced poroviscoelastic model was fitted to the experimental data obtained from the stress-relaxation experiments. The strain-dependent collagen network modulus (Efε) and the collagen orientation angle exhibited a negative linear correlation (r = −0.65, p < 0.01), while the permeability strain-dependency factor (M) and the collagen content exhibited a positive linear correlation (r = 0.56, p < 0.05). The non-fibrillar matrix modulus (Enf) also exhibited a positive linear correlation with the proteoglycan content (r = 0.54, p < 0.05). The study suggests that increased collagen orientation angle during OA primarily impairs the collagen network and the tensile stiffness of cartilage in a strain-dependent manner, while the decreased collagen content in OA facilitates fluid flow out of the tissue especially at high compressive strains. Thus, the results provide interesting and important information of the structure-function relationships of human hip joint cartilage and mechanisms during the progression of OA. PMCID: PMC3627049  PMID: 22858669 Articular Cartilage; Osteoarthritis; Collagen; Proteoglycans; Fourier transform infrared imaging; Polarized light microscopy; Finite element analysis; Fibril reinforced 17.  Establishment of an Index with Increased Sensitivity for Assessing Murine Arthritis  Establish quantitative outcomes for assessing murine knee arthritis and develop an Arthritis Index that incorporates multiple outcomes into a single calculation that provides enhanced sensitivity. Using an accepted model of meniscal/ligamentous injury (MLI)-induced osteoarthritis (OA), we assessed mouse knee arthritis using several approaches. Histology-based methods were performed to visualize joint tissues including articular cartilage and subchondral bone. Accepted histologic scoring methods and histomorphometry were performed to grade cartilage degeneration and determine articular cartilage area, respectively. MicroCT was used to visualize and quantify the bony structures of the joint including osteophytes and joint bone volume. A statistical algorithm was then developed that combined histologic scores and cartilage areas into a single Arthritis Index. MLI induced progressive, OA-like articular cartilage degeneration characterized by increasing (worsening) histologic score and decreasing cartilage area. MicroCT revealed osteophytes and increased joint bone volume between the femoral and tibial physes following MLI. Lastly, an Arthritis Index calculation was established, which incorporated histologic scoring and cartilage area. The Arthritis Index provided enhanced quantitative sensitivity in assessing the level of joint degeneration compared to either histologic scoring or cartilage area determination alone; when using the Index, between 29% and 43% fewer samples are needed to establish statistical significance in studies of murine arthritis. Arthritis in the mouse knee can be quantitatively assessed by histologic scoring, measuring cartilage area and determining joint bone volume. Enhanced sensitivity can be achieved by performing the Arthritis Index calculation, a novel method for quantitatively assessing mouse knee arthritis. PMCID: PMC3115505  PMID: 21374709 Osteoarthritis; Articular cartilage; Meniscal injury; Micro-computed tomography; Arthritis index 18.  Cartilage Pressure Distributions Provide a Footprint to Define Female Anterior Cruciate Ligament Injury Mechanisms  Bone bruises located on the lateral femoral condyle and posterolateral tibia are commonly associated with anterior cruciate ligament (ACL) injuries and may contribute to the high risk for knee osteoarthritis after ACL injury. The resultant footprint (location) of a bone bruise after ACL injury provides evidence of the inciting injury mechanism. (1) To analyze tibial and femoral articular cartilage pressure distributions during normal landing and injury simulations, and (2) to evaluate ACL strains for conditions that lead to articular cartilage pressure distributions similar to bone bruise patterns associated with ACL injury. The hypothesis was that combined knee abduction and anterior tibial translation injury simulations would demonstrate peak articular cartilage pressure distributions in the lateral femoral condyle and posterolateral tibia. The corollary hypothesis was that combined knee abduction and anterior tibial translation injury conditions would result in the highest ACL strains. Study Design Descriptive laboratory study. Prospective biomechanical data from athletes who subsequently suffered ACL injuries after testing (n = 9) and uninjured teammates (n = 390) were used as baseline input data for finite element model comparisons. Peak articular pressures that occurred on the posterolateral tibia and lateral femoral condyle were demonstrated for injury conditions that had a baseline knee abduction angle of 5°. Combined planar injury conditions of abduction/anterior tibial translation, anterior tibial translation/internal tibial rotation, or anterior tibial translation/external tibial rotation or isolated anterior tibial translation, external tibial rotation, or internal tibial rotation resulted in peak pressures in the posterolateral tibia and lateral femur. The highest ACL strains occurred during the combined abduction/anterior tibial translation condition in the group that had a baseline knee abduction angle of 5°. The results of this study support a valgus collapse as the major ACL injury mechanism that results from tibial abduction rotations combined with anterior tibial translation or external or internal tibial rotations. Clinical Relevance Reduction of large multiplanar knee motions that include abduction, anterior translation, and internal/external tibial motions may reduce the risk for ACL injuries and associated bone bruises. In particular, prevention of an abduction knee posture during initial contact of the foot with the ground may help prevent ACL injury. PMCID: PMC3412516  PMID: 21487121 bone bruise; ACL; articular cartilage; knee injury 19.  Use of Bone Morphogenic Protein-7 as a Treatment for Osteoarthritis  Osteoarthritis is a degenerative disorder resulting from breakdown of articular cartilage. Previous work has shown bone morphogenic protein-7 has a potential protective effect on cartilage during the development of osteoarthritis. The purpose of this study was to determine whether bone morphogenic protein-7 could decrease the amount of cartilage degradation in preexisting osteoarthritis. The rabbit ACLT model was used as a model of osteoarthritis. Bone morphogenic protein-7 was delivered via Alzet osmotic pump to the joint 4 weeks after anterior cruciate ligament transection; thus cartilage injury was preexisting. The experimental group showed less cartilage degradation than the controls, with an average Outerbridge score of 1.9 versus 2.6 for the controls. Histomorphometry showed a trend toward less cartilage degradation in the bone morphogenic protein-7 group when compared with controls. Semiquantitative real-time polymerase chain reaction showed a considerably greater expression of aggrecan in the bone morphogenic protein-7-treated cartilage when compared with controls and less expression of matrix metalloproteinase-3 and matrix metalloproteinase-13, important catabolic mediators. The synovial tissue of the experimental group also showed considerably less expression of matrix metalloproteinase-3, matrix metalloproteinase-13, and aggrecanase. These results indicate bone morphogenic protein-7 may reduce degradation of articular cartilage in osteoarthritis. PMCID: PMC2772903  PMID: 18941854 20.  Mesenchymal stem cell therapy in osteoarthritis: advanced tissue repair or intervention with smouldering synovial activation?  Although it is generally accepted that osteoarthritis is a degenerative condition of the cartilage, other tissues such as synovium in which immunological and inflammatory reactions occur contribute to the development of joint pathology. This sheds new light on the potential mechanism of action of mesenchymal stem cell therapy in osteoarthritis. Rather than tissue repair due to local transformation of injected mesenchymal stem cells to chondrocytes and filling defects in cartilage, such treatment might suppress synovial activation and indirectly ameliorate cartilage damage. Desando and co-workers report in Arthritis Research & Therapy that intra-articular delivery of adipose-derived stem cells attenuates progression of synovial activation and joint destruction in osteoarthritis in an experimental rabbit model. Clinical studies are warranted to see whether this approach might be a novel way to combat development of joint destruction in inflammatory subtypes of osteoarthritis. PMCID: PMC3672811  PMID: 23521980 Arthritis Research & Therapy  2005;7(3):R552-R559. Articular cartilage (hyaline cartilage) defects resulting from traumatic injury or degenerative joint disease do not repair themselves spontaneously. Therefore, such defects may require novel regenerative strategies to restore biologically and biomechanically functional tissue. Recently, tissue engineering using a complex of cells and scaffold has emerged as a new approach for repairing cartilage defects and restoring cartilage function. With the advent of this new technology, accurate methods for evaluating articular cartilage have become important. In particular, in vivo evaluation is essential for determining the best treatment. However, without a biopsy, which causes damage, articular cartilage cannot be accurately evaluated in a clinical context. We have developed a novel system for evaluating articular cartilage, in which the acoustic properties of the cartilage are measured by introducing an ultrasonic probe during arthroscopy of the knee joint. The purpose of the current study was to determine the efficacy of this ultrasound system for evaluating tissue-engineered cartilage in an experimental model involving implantation of a cell/scaffold complex into rabbit knee joint defects. Ultrasonic echoes from the articular cartilage were converted into a wavelet map by wavelet transformation. On the wavelet map, the percentage maximum magnitude (the maximum magnitude of the measurement area of the operated knee divided by that of the intact cartilage of the opposite, nonoperated knee; %MM) was used as a quantitative index of cartilage regeneration. Using this index, the tissue-engineered cartilage was examined to elucidate the relations between ultrasonic analysis and biochemical and histological analyses. The %MM increased over the time course of the implant and all the hyaline-like cartilage samples from the histological findings had a high %MM. Correlations were observed between the %MM and the semiquantitative histologic grading scale scores from the histological findings. In the biochemical findings, the chondroitin sulfate content increased over the time course of the implant, whereas the hydroxyproline content remained constant. The chondroitin sulfate content showed a similarity to the results of the %MM values. Ultrasonic measurements were found to predict the regeneration process of the tissue-engineered cartilage as a minimally invasive method. Therefore, ultrasonic evaluation using a wavelet map can support the evaluation of tissue-engineered cartilage using cell/scaffold complexes. PMCID: PMC1174952  PMID: 15899042 22.  Vulnerability of the superficial zone of immature articular cartilage to compressive injury  Arthritis and rheumatism  2010;62(10):3016-3027. The zonal composition and functioning of adult articular cartilage causes depth-dependent responses to compressive injury. In immature cartilage, shear and compressive modulus, collagen and glycosaminoglycan (GAG) content also vary with depth. However, there is little understanding of depth-dependent damage caused by injury. Since injury to immature knee joints most often causes articular cartilage lesions, our objectives were to characterize the zonal dependence of biomechanical, biochemical and matrix-associated changes cause by injury. Superficial and deeper zones disks from bovine calves were biomechanically characterized, injured (50% compression, 100%/sec) and re-characterized. Tissue compaction upon injury, GAG-density, GAG loss and biosynthesis were measured. Collagen-fiber-orientation and matrix damage was assessed using histology, Diffraction-Enhanced-X-Ray-Imaging, and texture analysis. Injured superficial disks showed surface disruption, compaction by 20.3±4.3%, and immediate biomechanical impairment: dynamic stiffness decreased to 7.1±3.3% of its initial value and equilibrium modulus was below detection. Tissue areas apparently intact by histology showed clear textural alterations. Injured deeper zones disks showed collagen crimping but remained undamaged and biomechanically intact. Superficial zone disks did not lose GAG immediately after injury but lost 17.8±1.4% by 48h; deeper zones disks lost only 2.8±0.3% GAG. Biomechanical impairment was primarily associated with structural damage. The soft superficial zone of immature cartilage is vulnerable to compressive injury causing superficial matrix disruption, extensive compaction, and textural alteration, and resulting in immediate loss of biomechanical function. In conjunction with delayed superficial GAG loss, these changes may predispose the articular surface to further softening, damage, and increased risk of developing secondary OA. PMCID: PMC2952071  PMID: 20556809 23.  Chondrogenesis, chondrocyte differentiation, and articular cartilage metabolism in health and osteoarthritis  Chondrogenesis occurs as a result of mesenchymal cell condensation and chondroprogenitor cell differentiation. Following chondrogenesis, the chondrocytes remain as resting cells to form the articular cartilage or undergo proliferation, terminal differentiation to chondrocyte hypertrophy, and apoptosis in a process termed endochondral ossification, whereby the hypertrophic cartilage is replaced by bone. Human adult articular cartilage is a complex tissue of matrix proteins that varies from superficial to deep layers and from loaded to unloaded zones. A major challenge to efforts to repair cartilage by stem cell-based and other tissue-engineering strategies is the inability of the resident chondrocytes to lay down a new matrix with the same properties as it had when it was formed during development. Thus, understanding and comparing the mechanisms of cartilage remodeling during development, osteoarthritis (OA), and aging may lead to more effective strategies for preventing cartilage damage and promoting repair. The pivotal proteinase that marks OA progression is matrix metalloproteinase 13 (MMP-13), the major type II collagen-degrading collagenase, which is regulated by both stress and inflammatory signals. We and other investigators have found that there are common mediators of these processes in human OA cartilage. We also observe temporal and spatial expression of these mediators in early through late stages of OA in mouse models and are analyzing the consequences of knockout or transgenic overexpression of critical genes. Since the chondrocytes in adult human cartilage are normally quiescent and maintain the matrix in a low turnover state, understanding how they undergo phenotypic modulation and promote matrix destruction and abnormal repair in OA may to lead to identification of critical targets for therapy to block cartilage damage and promote effective cartilage repair. PMCID: PMC3403254  PMID: 22859926 articular cartilage; chondrogenesis; inflammation; mouse models; osteoarthritis PMCID: PMC3392795  PMID: 22293240 25.  Platelet-Rich Plasma Treatment in Symptomatic Patients With Knee Osteoarthritis  Sports Health  2012;4(2):162-172. Study Design: Case series. Materials and Methods: Clinical Relevance: There are only a few studies of PRP treatment for cartilage on osteoarthritic knees. Different PRP products might be more or less appropriate to treat different types of tissues and pathologies. The clinical efficacy of PRP remains under debate, and a standardized protocol has not yet been established. PMCID: PMC3435904  PMID: 23016084 knee; cartilage; osteoarthritis; platelet-rich plasma; microfracture; cartilage shaving Results 1-25 (886513)
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Search tips Search criteria Results 1-25 (68) Clipboard (0) Select a Filter Below Year of Publication more » Document Types 1.  Function and Evolution of DNA Methylation in Nasonia vitripennis  PLoS Genetics  2013;9(10):e1003872. Author Summary PMCID: PMC3794928 2.  Heritability and Inter-Population Differences in Lipid Profiles of Drosophila melanogaster  PLoS ONE  2013;8(8):e72726. PMCID: PMC3754969  PMID: 24013349 3.  Impact of Genetic Architecture on the Relative Rates of X versus Autosomal Adaptive Substitution  PMCID: PMC3408067  PMID: 22319138 PMCID: PMC3390784  PMID: 22387199 Antioxidant enzymes; Lung function 5.  Sex-Differential Selection and the Evolution of X Inactivation Strategies  PLoS Genetics  2013;9(4):e1003440. Author Summary PMCID: PMC3630082  PMID: 23637618 PMCID: PMC3119407  PMID: 21716718 7.  Recent Explosive Human Population Growth Has Resulted in an Excess of Rare Genetic Variants  PMCID: PMC3586590  PMID: 22582263 8.  Gene-Based Testing of Interactions in Association Studies of Quantitative Traits  PLoS Genetics  2013;9(2):e1003321. Author Summary PMCID: PMC3585009  PMID: 23468652 9.  The BDNF Val66Met polymorphism moderates early deprivation effects on attention problems  Development and psychopathology  2012;24(4):1215-1223. Adverse early care is associated with attention regulatory problems, but not all so exposed develop attention problems. In a sample of 612 youth (girls=432, M=11.82 yrs, SD=1.5) adopted from institutions (e.g., orphanages) in 25 countries, we examined whether the Val66Met polymorphism of the BDNF gene moderates attention problems associated with the duration of institutional care. Parent-reported attention problem symptoms were collected using the MacArthur Health and Behavior Questionnaire. DNA was genotyped for the BDNF Val66Met (rs6265) SNP. Among youth from SE Asia, the predominant genotype was Val/Met, while among youth from Russia/Europe and Caribbean/South America the predominant genotype was Val/Val. For analysis, youth were grouped as carrying Val/Val or AnyMet alleles. Being female, being from SE Asia, and being younger when adopted were associated with fewer attention regulatory problem symptoms. Youth carrying at least one copy of the Met allele were more sensitive to the duration of deprivation, yielding an interaction that followed a differential susceptibility pattern. Thus, youth with Val/Met or Met/Met genotypes exhibited fewer symptoms than Val/Val genotypes when adoption was very early and more symptoms when adoption occurred later in development. Similar patterns were observed when SE Asian youth and youth from other parts of the world were analyzed separately. PMCID: PMC3581017  PMID: 23062292 10.  Integration of single and multicellular wound responses  Current biology : CB  2009;19(16):1389-1395. Single cells and multicellular tissues rapidly heal wounds. These processes are considered distinct, but one mode of healing—Rho GTPase-dependent formation and closure of a purse string of actin filaments (F-actin) and myosin-2 around wounds—occurs in single cells (1,2) and in epithelia (3-10). Here we show that wounding of one cell in Xenopus embryos elicits Rho GTPase activation around the wound and at the nearest cell-cell junctions in the neighbor cells. F-actin and myosin-2 accumulate at the junctions as well as around the wound itself, and as the resultant actomyosin array closes over the wound site, junctional F-actin and myosin-2 become mechanically integrated with the actin and myosin-2 around the wound, forming a hybrid purse string. When cells are ablated rather than wounded, Rho GTPase activation and F-actin accumulation occur at cell-cell junctions surrounding the ablated cell, and the purse string closes the hole in the epithelium. Elevation of intracellular free calcium, an essential upstream signal for the single cell wound response (2,11), also occurs at the cell-cell contacts and in neighbor cells. Thus, the single and multicellular purse string wound responses represent points on a signaling and mechanical continuum that are integrated by cell-cell junctions. PMCID: PMC3561667  PMID: 19631537 11.  Female Influence on Pre- and Post-copulatory Sexual Selection and its Genetic Basis in Drosophila melanogaster  Molecular ecology  2011;20(19):4098-4108. Genetic variation among females is likely to influence the outcome of both pre- and post-copulatory sexual selection in Drosophila melanogaster. Here we use association testing to survey natural variation in 10 candidate female genes for their effects on female reproduction. Females from 91 chromosome 2 substitution lines were scored for phenotypes affecting pre- and post-copulatory sexual selection such as mating and remating rate, propensity to use sperm from the second male to mate, and measures of fertility. There were significant genetic contributions to phenotypic variation for all the traits measured. Resequencing of the 10 candidate genes in the 91 lines yielded 68 nonsynonymous polymorphisms which were tested for associations with the measured phenotypes. Twelve significant associations (markerwise P < 0.01) were identified. Polymorphisms in the putative serine protease homolog CG9897 and the putative odorant binding protein CG11797 associated with female propensity to remate and met an experimentwise significance of P < 0.05. Several other associations, including those impacting both fertility and female remating rate suggest that sperm storage might be an important factor mitigating female influence on sexual selection. PMCID: PMC3183161  PMID: 21902747 Sperm competition; association testing; female mating; sexual selection; genotype-phenotype 12.  Knowledge-Driven Analysis Identifies a Gene–Gene Interaction Affecting High-Density Lipoprotein Cholesterol Levels in Multi-Ethnic Populations  PLoS Genetics  2012;8(5):e1002714. Total cholesterol, low-density lipoprotein cholesterol, triglyceride, and high-density lipoprotein cholesterol (HDL-C) levels are among the most important risk factors for coronary artery disease. We tested for gene–gene interactions affecting the level of these four lipids based on prior knowledge of established genome-wide association study (GWAS) hits, protein–protein interactions, and pathway information. Using genotype data from 9,713 European Americans from the Atherosclerosis Risk in Communities (ARIC) study, we identified an interaction between HMGCR and a locus near LIPC in their effect on HDL-C levels (Bonferroni corrected Pc = 0.002). Using an adaptive locus-based validation procedure, we successfully validated this gene–gene interaction in the European American cohorts from the Framingham Heart Study (Pc = 0.002) and the Multi-Ethnic Study of Atherosclerosis (MESA; Pc = 0.006). The interaction between these two loci is also significant in the African American sample from ARIC (Pc = 0.004) and in the Hispanic American sample from MESA (Pc = 0.04). Both HMGCR and LIPC are involved in the metabolism of lipids, and genome-wide association studies have previously identified LIPC as associated with levels of HDL-C. However, the effect on HDL-C of the novel gene–gene interaction reported here is twice as pronounced as that predicted by the sum of the marginal effects of the two loci. In conclusion, based on a knowledge-driven analysis of epistasis, together with a new locus-based validation method, we successfully identified and validated an interaction affecting a complex trait in multi-ethnic populations. Author Summary Genome-wide association studies (GWAS) have identified many loci associated with complex human traits or diseases. However, the fraction of heritable variation explained by these loci is often relatively low. Gene–gene interactions might play a significant role in complex traits or diseases and are one of the many possible factors contributing to the missing heritability. However, to date only a few interactions have been found and validated in GWAS due to the limited power caused by the need for multiple-testing correction for the very large number of tests conducted. Here, we used three types of prior knowledge, known GWAS hits, protein–protein interactions, and pathway information, to guide our search for gene–gene interactions affecting four lipid levels. We identified an interaction between HMGCR and a locus near LIPC in their effect on high-density lipoprotein cholesterol (HDL-C) and another pair of loci that interact in their effect on low-density lipoprotein cholesterol (LDL-C). We validated the interaction on HDL-C in a number of independent multiple-ethnic populations, while the interaction underlying LDL-C did not validate. The prior knowledge-driven searching approach and a locus-based validation procedure show the potential for dissecting and validating gene–gene interactions in current and future GWAS. PMCID: PMC3359971  PMID: 22654671 13.  Identification of avian W-linked contigs by short-read sequencing  BMC Genomics  2012;13:183. The female-specific W chromosomes and male-specific Y chromosomes have proven difficult to assemble with whole-genome shotgun methods, creating a demand for new approaches to identify sequence contigs specific to these sex chromosomes. Here, we develop and apply a novel method for identifying sequences that are W-specific. Using the Illumina Genome Analyzer, we generated sequence reads from a male domestic chicken (ZZ) and mapped them to the existing female (ZW) genome sequence. This method allowed us to identify segments of the female genome that are underrepresented in the male genome and are therefore likely to be female specific. We developed a Bayesian classifier to automate the calling of W-linked contigs and successfully identified more than 60 novel W-specific sequences. Our classifier can be applied to improve heterogametic whole-genome shotgun assemblies of the W or Y chromosome of any organism. This study greatly improves our knowledge of the W chromosome and will enhance future studies of avian sex determination and sex chromosome evolution. PMCID: PMC3428670  PMID: 22583744 Sex chromosomes; Next-generation sequencing 14.  Contrasting human X-linked and autosomal variation in population-scale whole genome sequencing  Nature genetics  2011;43(8):741-743. The ratio of genetic diversity on chromosome X to that on the autosomes is sensitive to both natural selection and demography. Based on whole-genome sequences of 69 females, we report that while this ratio increases with genetic distance from genes across populations, it is lower in Europeans than in West Africans independent of proximity to genes. This relative reduction is most parsimoniously explained by differences in demographic history without the need to invoke natural selection. PMCID: PMC3145052  PMID: 21775991 15.  Environmental and genetic perturbations reveal different networks of metabolic regulation  Measurement of metabolic and physiological parameters in replicated crosses of Drosophila melanogaster inbred lines reveals that environmental and genetic perturbations uncover substantially different networks of metabolic regulation. We collected extensive data on enzyme activities and physiological parameters from replicated crosses of D. melanogaster inbred lines.We implemented a multivariate hierarchical Bayesian model to separately assess genetic and environmental covariation among system components and infer metabolic regulatory networks.Networks revealed by both environmental and genetic perturbations are similar among populations and between sexes.Environmental and genetic networks differ substantially, suggesting that environmental changes and mutations would have different systemic effects even when their primary targets are the same. Progress in systems biology depends on accurate descriptions of biological networks. Connections in a regulatory network are identified as correlations of gene expression across a set of environmental or genetic perturbations. To use this information to predict system behavior, we must test how the nature of perturbations affects topologies of networks they reveal. To probe this question, we focused on metabolism of Drosophila melanogaster. Our source of perturbations is a set of crosses among 92 wild-derived lines from five populations, replicated in a manner permitting separate assessment of the effects of genetic variation and environmental fluctuation. We directly assayed activities of enzymes and levels of metabolites. Using a multivariate Bayesian model, we estimated covariance among metabolic parameters and built fine-grained probabilistic models of network topology. The environmental and genetic co-regulation networks are substantially the same among five populations. However, genetic and environmental perturbations reveal qualitative differences in metabolic regulation, suggesting that environmental shifts, such as diet modifications, produce different systemic effects than genetic changes, even if the primary targets are the same. PMCID: PMC3738848  PMID: 22186737 Bayesian model; G matrix; hierarchical model; metabolic network Sex-biased genes -- genes that are differentially expressed within males and females -- are nonrandomly distributed across animal genomes, with sex chromosomes and autosomes often carrying markedly different concentrations of male- and female-biased genes. These linkage patterns are often gene- and lineage-dependent, differing between functional genetic categories and between species. While sex-specific selection is often hypothesized to shape the evolution of sex-linked and autosomal gene content, population genetics theory has yet to account for many of the gene- and lineage-specific idiosyncrasies emerging from the empirical literature. With the goal of improving the connection between evolutionary theory and a rapidly growing body of genome-wide empirical studies, we extend previous population genetics theory of sex-specific selection by developing and analyzing a biologically informed model that incorporates sex linkage, pleiotropy, recombination, and epistasis, factors that are likely to vary between genes and between species. Our results demonstrate that sex-specific selection and sex-specific recombination rates can generate, and are compatible with, the gene- and species-specific linkage patterns reported in the genomics literature. The theory suggests that sexual selection may strongly influence the architectures of animal genomes, as well as the chromosomal distribution of fixed substitutions underlying sexually dimorphic traits. PMCID: PMC2998557  PMID: 20874735 sex chromosomes; sexual antagonism; antagonistic pleiotropy; epistasis; sex-biased genes 17.  Folate network genetic variation, plasma homocysteine, and global genomic methylation content: a genetic association study  BMC Medical Genetics  2011;12:150. Sequence variants in genes functioning in folate-mediated one-carbon metabolism are hypothesized to lead to changes in levels of homocysteine and DNA methylation, which, in turn, are associated with risk of cardiovascular disease. 330 SNPs in 52 genes were studied in relation to plasma homocysteine and global genomic DNA methylation. SNPs were selected based on functional effects and gene coverage, and assays were completed on the Illumina Goldengate platform. Age-, smoking-, and nutrient-adjusted genotype--phenotype associations were estimated in regression models. Using a nominal P ≤ 0.005 threshold for statistical significance, 20 SNPs were associated with plasma homocysteine, 8 with Alu methylation, and 1 with LINE-1 methylation. Using a more stringent false discovery rate threshold, SNPs in FTCD, SLC19A1, and SLC19A3 genes remained associated with plasma homocysteine. Gene by vitamin B-6 interactions were identified for both Alu and LINE-1 methylation, and epistatic interactions with the MTHFR rs1801133 SNP were identified for the plasma homocysteine phenotype. Pleiotropy involving the MTHFD1L and SARDH genes for both plasma homocysteine and Alu methylation phenotypes was identified. No single gene was associated with all three phenotypes, and the set of the most statistically significant SNPs predictive of homocysteine or Alu or LINE-1 methylation was unique to each phenotype. Genetic variation in folate-mediated one-carbon metabolism, other than the well-known effects of the MTHFR c.665C>T (known as c.677 C>T, rs1801133, p.Ala222Val), is predictive of cardiovascular disease biomarkers. PMCID: PMC3266217  PMID: 22103680 18.  Drosophila Duplication Hotspots Are Associated with Late-Replicating Regions of the Genome  PLoS Genetics  2011;7(11):e1002340. Duplications play a significant role in both extremes of the phenotypic spectrum of newly arising mutations: they can have severe deleterious effects (e.g. duplications underlie a variety of diseases) but can also be highly advantageous. The phenotypic potential of newly arisen duplications has stimulated wide interest in both the mutational and selective processes shaping these variants in the genome. Here we take advantage of the Drosophila simulans–Drosophila melanogaster genetic system to further our understanding of both processes. Regarding mutational processes, the study of two closely related species allows investigation of the potential existence of shared duplication hotspots, and the similarities and differences between the two genomes can be used to dissect its underlying causes. Regarding selection, the difference in the effective population size between the two species can be leveraged to ask questions about the strength of selection acting on different classes of duplications. In this study, we conducted a survey of duplication polymorphisms in 14 different lines of D. simulans using tiling microarrays and combined it with an analogous survey for the D. melanogaster genome. By integrating the two datasets, we identified duplication hotspots conserved between the two species. However, unlike the duplication hotspots identified in mammalian genomes, Drosophila duplication hotspots are not associated with sequences of high sequence identity capable of mediating non-allelic homologous recombination. Instead, Drosophila duplication hotspots are associated with late-replicating regions of the genome, suggesting a link between DNA replication and duplication rates. We also found evidence supporting a higher effectiveness of selection on duplications in D. simulans than in D. melanogaster. This is also true for duplications segregating at high frequency, where we find evidence in D. simulans that a sizeable fraction of these mutations is being driven to fixation by positive selection. Author Summary DNA duplications are important contributors to the phenotypic differences observed between individuals. These mutations can disrupt the normal functioning of genes and so are often associated with disease. But because they can add genetic information they can also lead to evolutionary change. Understanding how selection and non-random mutation processes shape the distribution of duplications throughout the genome is important to elucidate both the medical and evolutionary impacts of these mutations. Here, we examined the roles of selection and mutation in shaping patterns of duplication polymorphisms across the genomes of the fruit fly Drosophila melanogaster and its sister species, D. simulans. We found that selection is pervasive in both genomes but is more efficient in D. simulans than in D. melanogaster. We also found that these two species have shared duplication hotspots, i.e. orthologous regions experiencing high rates of duplication in the two genomes. After excluding the hypothesis that Drosophila duplication hotspots are associated with regions of the genome rich in segmental duplications (as observed for mammalian genomes), we show that they are associated with late-replicating regions of the genome. Our work therefore proposes a link between DNA replication and rates of duplication across the genome. PMCID: PMC3207856  PMID: 22072977 19.  Functional Regulatory Divergence of the Innate Immune System in Interspecific Drosophila Hybrids  Molecular Biology and Evolution  2010;27(11):2596-2605. In order to investigate divergence of immune regulation among Drosophila species, we have engaged in a study of innate immune function in F1 hybrids of Drosophila melanogaster and D. simulans. If pathways have diverged between the species such that incompatibilities have arisen between interacting components of the immune network, we expect the hybrids to display dysregulation of immune genes. We have quantified gene induction in hybrid and parental flies in response to bacterial infection. These results show that although the hybrids do not suffer widespread immune breakdown, they show significantly different regulation of many immune genes relative to the parents. We examine this divergence in terms of additivity and expression differences among genes, observing distinct patterns of dysregulation among functional groups within the pathways of the innate immune system. The functional groups most sensitive to misexpression in the hybrids are the downstream components of the network, indicative of some propagation of dysregulation throughout the immune pathways. Interestingly, this dysregulation does not appear to associate with phenotypic differences in bacterial load after infection in hybrids, possibly highlighting some robustness of function of the innate immune response to perturbations like hybridization. PMCID: PMC3107606  PMID: 20551040 Drosophila; innate immunity; hybrid dysregulation; misexpression; functional divergence 20.  Contrasting Methods of Quantifying Fine Structure of Human Recombination  There has been considerable excitement over the ability to construct linkage maps based only on genome-wide genotype data for single nucleotide polymorphic sites (SNPs) in a population sample. These maps, which are derived from estimates of linkage disequilibrium (LD), rely on population genetics theory to relate the decay of LD to the local rate of recombination, but other population processes also come into play. Here we contrast these LD maps to the classically derived, pedigree-based human recombination maps. The LD maps have a level of resolution greatly exceeding that of the pedigree maps, and at this fine scale, sperm typing allows a means of validation. While at a gross level both the pedigree maps and the sperm typing methods generally agree with LD maps, there are significant local differences between them, and the fact that these maps measure different genetic features should be remembered when using them for other genetic inferences. PMCID: PMC2980829  PMID: 20690817 linkage disequilibrium; genetic linkage; hotspot; population recombination rate; recombination intensity 21.  Translocation of Y-Linked Genes to the Dot Chromosome in Drosophila pseudoobscura  Molecular Biology and Evolution  2010;27(7):1612-1620. One of the most striking cases of sex chromosome reorganization in Drosophila occurred in the lineage ancestral to Drosophila pseudoobscura, where there was a translocation of Y-linked genes to an autosome. These genes went from being present only in males, never recombining, and having an effective population size of 0.5N to a state of autosomal linkage, where they are passed through both sexes, may recombine, and their effective population size has quadrupled. These genes appear to be functional, and they underwent a drastic reduction in intron size after the translocation. A Y-autosome translocation may pose problems in meiosis if the rDNA locus responsible for X–Y pairing had also moved to an autosome. In this study, we demonstrate that the Y-autosome translocation moved Y-linked genes onto the dot chromosome, a small, mainly heterochromatic autosome with some sex chromosome–like properties. The rDNA repeats occur exclusively on the X chromosome in D. pseudoobscura, but we found that the new Y chromosome of this species harbors four clusters bearing only the intergenic spacer region (IGS) of the rDNA repeats. This arrangement appears analogous to the situation in Drosophila simulans, where X-rDNA to Y-IGS pairing could be responsible for X–Y chromosome pairing. We postulate that the nascent D. pseudoobscura Y chromosome acquired and amplified copies of the IGS, suggesting a potential mechanism for X–Y pairing in D. pseudoobscura. PMCID: PMC2912472  PMID: 20147437 Drosophila pseudoobscura; Y chromosome evolution; dot chromosome; rDNA 22.  Association between Sex-Biased Gene Expression and Mutations with Sex-Specific Phenotypic Consequences in Drosophila  Genome-wide mRNA transcription profiles reveal widespread molecular sexual dimorphism or “sex-biased” gene expression, yet the relationship between molecular and phenotypic sexual dimorphism remains unclear. A major unresolved question is whether sex-biased genes typically perform male- and female-specific functions (whether these genes have sex-biased phenotypic or fitness consequences) or have similar functional importance for both sexes. To elucidate the relationship between sex-biased transcription and sex-biased fitness consequences, we analyzed a large data set of lethal, visible, and sterile mutations that have been mapped to the Drosophila melanogaster genome. The data permitted us to classify genes according to their sex-specific mutational effects and to infer the relationship between sex-biased transcription level and sex-specific fitness consequences. We find that mutations in female-biased genes are (on average) more deleterious to females than to males and that mutations in male-biased genes tend to be more deleterious to males than to females. Nevertheless, mutations in most sex-biased genes have similar phenotypic consequences for both sexes, which suggests that sex-biased transcription is not necessarily associated with functional genetic differentiation between males and females. These results have interesting implications for the evolution of sexual dimorphism and sex-specific adaptation. PMCID: PMC3048362  PMID: 21292631 sexual dimorphism; sexual selection; sexual antagonism; deleterious mutation; fitness variation 23.  Targets of Balancing Selection in the Human Genome  Molecular Biology and Evolution  2009;26(12):2755-2764. PMCID: PMC2782326  PMID: 19713326 overdominance; frequency-dependent selection; heterosis; human evolution; population genetics; human diversity 24.  BDNF as a Model System for examining Gene by Environment Interactions across Development  Neuroscience  2009;164(1):108-120. There has been a dramatic rise in gene x environment studies of human behavior over the past decade that has moved the field beyond simple nature versus nurture debates. These studies offer promise in accounting for more variability in behavioral and biological phenotypes than studies that focus on genetic or experiential factors alone. They also provide clues into mechanisms of modifying genetic risk or resilience in neurodevelopmental disorders. Yet, it is rare that these studies consider how these interactions change over the course of development. In this paper, we describe research that focuses on the impact of a polymorphism in a brain-derived neurotrophic factor (BDNF) gene, known to be involved in learning and development. Specifically we present findings that assess the effects of genotypic and environmental loadings on neuroanatomic and behavioral phenotypes across development. The findings illustrate the use of a genetic mouse model that mimics the human polymorphism, to constrain the interpretation of gene-environment interactions across development in humans. PMCID: PMC2760671  PMID: 19358879 BDNF; development; environment; genetics; neurodevelopment; endophenotype 25.  Life After GWA Studies  Science (New York, N.Y.)  2009;326(5950):239-240. Genome-wide association findings should be integrated into a wider scope of information including biological processes and environments. PMCID: PMC2933170  PMID: 19815762 Results 1-25 (68)
http://pubmedcentralcanada.ca/pmcc/solr/reg?pageSize=25&term=author%3A(%22Weiss%2C+Scott+T.%22)&sortby=score+desc&filterAuthor=author%3A(%22Clark%2C+Andrew+G%22)
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Search tips Search criteria Results 1-7 (7) Clipboard (0) Select a Filter Below Year of Publication Document Types 1.  Smoking cessation is challenging even for patients recovering from lung cancer surgery with curative intent  Although it is recommended that smokers undergoing surgery for lung cancer quit smoking to reduce post-operative complications, few studies have examined patterns of smoking in the peri-operative period. The goals of this study were to determine: 1) patterns of smoking during post-operative recovery, 2) types of cessation strategies used to quit smoking, and 3) factors related to smoking after lung cancer surgery. Data were collected from 94 patients through chart review, tobacco, health-status, and symptom questionnaires at 1, 2, and 4-months after surgery. Smoking status was assessed through self-report and urinary cotinine measurement. Eighty-four patients (89%) were ever-smokers and 35 (37%) reported smoking at diagnosis. Thirty-nine (46%) ever-smokers remained abstinent, 13 (16%) continued smoking at all time-points, and 32 (38%) relapsed. Ten (46%) of those who relapsed were former-smokers and had not smoked for at least 1-year. Sixteen (46%) of those who were smoking at diagnosis received cessation assistance with pharmacotherapy being the most common strategy. Factors associated with smoking during recovery were younger age and quitting smoking ≤ six-months before the diagnosis of lung cancer. Factors that were marginally significant were lower educational level, male gender, lower number of comorbidities, and the presence of pain Only half of those who were smoking received assistance to quit prior to surgery. Some patients were unable to quit and relapse rates post-surgery were high even among those who quit more than 1-year prior. Innovative programs incorporating symptom management and relapse prevention may enhance smoking abstinence during post-operative care. PMCID: PMC3805262  PMID: 19321223 lung cancer; thoracic surgery; smoking cessation; symptom management 2.  Quality of Life and Symptom Burden among Long Term Lung Cancer Survivors: Changing and Adapting  Information is limited regarding health-related quality of life (QOL) status of long term (greater than five years) lung cancer survivors (LTLCS). Obtaining knowledge about their QOL changes over time is a critical step towards improving poor and maintaining good QOL. The primary aim of this study was to conduct a seven-year longitudinal study in survivors of primary lung cancer that identified factors associated with either decline or improvement in QOL over time. Between 1997 and 2003, 447 LTLCS were identified and followed through 2007 using validated questionnaires; data on overall QOL and specific symptoms were at two periods: short-term (less than three years) and long-term post diagnosis. The main analyses were of clinically significant changes (greater than 10%) and factors associated with overall QOL and symptom burden for each period and for changes over time. Three hundred two (68%) underwent surgical resection only and 122 (27%) received surgical resection and radiation/chemotherapy. Recurrent or new lung malignancies were observed in 84 (19%) survivors. Significant decline or improvement in overall QOL over time were reported in 155 (35%) and 67 (15%) of 447 survivors, respectively. Among the 155 whose QOL declined, significantly worsened symptoms were fatigue (69%), pain (59%), dyspnea (58%), depressed appetite (49%), and coughing (42%). The symptom burden did not lessen among the 67 who reported improvement, suggesting survivors had adapted to their compromised physical condition. LTLCS suffered substantial symptom burden that significantly impaired their QOL, indicating a need for targeted interventions to alleviate their symptoms. PMCID: PMC3241852  PMID: 22134070 lung cancer; long term survivors; health-related quality of life; symptoms; pain; dyspnea; fatigue 3.  Are quit attempts among U.S. female nurses who smoke different from female smokers in the general population? An analysis of the 2006/2007 tobacco use supplement to the current population survey  BMC Women's Health  2012;12:4. Smoking is a significant women's health issue. Examining smoking behaviors among occupational groups with a high prevalence of women may reveal the culture of smoking behavior and quit efforts of female smokers. The purpose of this study was to examine how smoking and quitting characteristics (i.e., ever and recent quit attempts) among females in the occupation of nursing are similar or different to those of women in the general population. Cross-sectional data from the Tobacco Use Supplement of the Current Population Survey 2006/2007 were used to compare smoking behaviors of nurses (n = 2, 566) to those of non-healthcare professional women (n = 93, 717). Smoking characteristics included years of smoking, number of cigarettes, and time to first cigarette with smoking within the first 30 minutes as an indicator of nicotine dependence. Logistic regression models using replicate weights were used to determine correlates of ever and previous 12 months quit attempts. Nurses had a lower smoking prevalence than other women (12.1% vs 16.6%, p < 0.0001); were more likely to have ever made a quit attempt (77% vs 68%, p = 0.0002); but not in the previous 12 months (42% vs 43%, p = 0.77). Among those who ever made a quit attempt, nurses who smoked within 30 minutes of waking, were more likely to have made a quit attempt compared to other women (OR = 3.1, 95% CI: 1.9, 5.1). When considering quit attempts within the last 12 months, nurses whose first cigarette was after 30 minutes of waking were less likely to have made a quit attempt compared to other females (OR = 0.69, 95% CI: 0.49, 0.98). There were no other significant differences in ever/recent quitting. Smoking prevalence among female nurses was lower than among women who were not in healthcare occupations, as expected. The lack of difference in recent quit efforts among female nurses as compared to other female smokers has not been previously reported. The link between lower level of nicotine dependence, as reflected by the longer time to first cigarette, and lower quit attempts among nurses needs further exploration. PMCID: PMC3328253  PMID: 22429917 4.  National Cancer Institute Conference on Treating Tobacco Dependence at Cancer Centers  Journal of Oncology Practice  2011;7(3):178-182. The National Cancer Institute cancer centers possess the credibility to help smokers quit. With the greater life expectancies forecast for patients with cancer, addressing smoking at cancer centers has taken on greater importance. PMCID: PMC3092659  PMID: 21886500 5.  Quality of Life Supersedes the Classic Prognosticators for Long-Term Survival in Locally Advanced Non–Small-Cell Lung Cancer: An Analysis of RTOG 9801  Journal of Clinical Oncology  2009;27(34):5816-5822. To determine the added value of quality of life (QOL) as a prognostic factor for overall survival (OS) in patients with locally advanced non–small-cell lung cancer (NSCLC) treated on Radiation Therapy Oncology Group RTOG-9801. Patients and Methods Two hundred forty-three patients with stage II/IIIAB NSCLC received induction paclitaxel and carboplatin (PC) and then concurrent weekly PC and hyperfractionated radiation (to 69.6 Gy). Patients were randomly assigned to amifostine (AM) or no AM during chemoradiotherapy. The following pretreatment factors were analyzed as prognostic factors for OS: Karnofsky performance status, stage, sex, age, race, marital status, histology, tumor location, hemoglobin, tobacco use, treatment arm (AM v no AM) and QOL scores (European Organisation for Research and Treatment of Cancer Quality of Life Questionnaire C30 [QLQ-C30] and Lung Cancer 13 [LC-13]). A multivariate (MVA) Cox proportional hazards model was performed using a backwards selection process. Of the 239 analyzable patients, 91% had a baseline global QOL score. Median follow-up time was 59 months for patients still alive and 17 months for all patients. Median baseline QLQ-C30 global QOL score was 66.7 on both treatment arms. Whether the global QOL score was treated as a dichotomized variable (based on the median score) or a continuous variable, all other variables fell out of the MVA for OS. Patients with a global QOL score less than 66.7 had an approximately 70% higher rate of death than patients with scores ≥ 66.7 (P = .004). A 10-point higher baseline global QOL score corresponded to a decrease in the hazard of death by approximately 10% (P = .004). The other independent QOL predictors for OS were the QLQ-C30 physical functioning (P = .011) and LC-13 dyspnea scores (P = .012). In this analysis, baseline global QOL score replaced known prognostic factors as the sole predictor of long-term OS for patients with locally advanced NSCLC. PMCID: PMC2793002  PMID: 19858383 6.  Symptom Management in Hepatocellular Carcinoma  Worldwide, hepatocellular carcinoma (HCC) causes approximately one million deaths every year. Due to advanced stage at diagnosis, HCC carries a five-year survival rate of <5%, if diagnosed with unresectable disease. Incidence for HCC is higher in males and individuals of Asian descent, where viral hepatitis is endemic and a leading cause of HCC. The purpose of this article is to provide an overview of the complexity in symptom management of patients with HCC. The occurrence of multiple symptoms in HCC patients is common, and may include pain, fatigue, weight loss, and obstructive syndromes such as ascites and jaundice. Because of the limitations in the efficacy of current treatment options for HCC, aggressive symptom management is key to preserving physical functioning and QOL in this cancer population. Oncology nurses can play an integral role in symptom management of HCC patients. A multidisciplinary team approach to symptom management of HCC patients is critical due to the multidimensionality of common symptoms in this cancer population. PMCID: PMC2881685  PMID: 18842532 7.  Smoking Cessation and Lung Cancer: Oncology Nurses Can Make a Difference  Seminars in oncology nursing  2008;24(1):16-26. Provide an overview of the impact of smoking after a diagnosis of lung cancer, discuss the relationship between smoking cessation and improved outcomes during the lung cancer trajectory, present information about tobacco dependence evidence-based treatments, reimbursement for these treatments, and tobacco-related resources available for patients and health care professionals, and emphasize the important role of nurses. Published articles, reports, websites, and research studies. Tobacco use is associated with 30% of cancer deaths. Prevention of tobacco use and cessation are primary ways to prevent lung cancer. However, even after a diagnosis of lung cancer, smoking cessation is important in improving survival and quality of life. Although effective tobacco dependence treatments are available to help smokers quit smoking, persistent efforts over repeated contacts may be necessary to achieve long-term cessation. Oncology nursing action is essential in the identification of and intervention with patients who struggle with tobacco dependence after diagnosis. PMCID: PMC2249620  PMID: 18222148 smoking cessation interventions; tobacco dependence treatment and lung cancer Results 1-7 (7)
http://pubmedcentralcanada.ca/pmcc/solr/reg?pageSize=25&term=issn%3A0749-2081&sortby=score+desc&filterAuthor=author%3A(%22Sarna%2C+Linda%22)
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MotoGP review (PSP) CNET Editors' Rating 3.5 stars Very good Review Date: Average User Rating 0.0 stars No reviews. Write a review MotoGP is a good technical racing game, but the small selection of tracks and rigid artificial intelligence take some of the variety and excitement out of it. The MotoGP racing franchise from Namco Bandai Games has remained exclusive to the PlayStation 2 since its 2000 debut, but now the series is racing on the PlayStation Portable. MotoGP for the PSP offers a competent mix of arcade- and sim-style racing with fully licensed riders and motorcycles. However, the short track list, somewhat lacking season mode, and lifeless artificial intelligence leave MotoGP thin on content. MotoGP for the PSP contains all the riders from the 2005 MotoGP season, so you can race as or try to defeat riders like Valentino Rossi from Italy, Sete Gibernau from Spain, Makoto Tamada from Japan, and many more. The two main modes in MotoGP are arcade and season. In arcade mode, you can participate in a single race against 20 real-world riders on any of the eight licensed tracks in the game. Season mode is a more robust and involved racing experience, but it still feels shallow. There are two separate modes that let you either race a single season as one of the real-world MotoGP riders or choose a generic rider to race in a succession of seasons. You'll earn points that depend on how you place in each season race, and these determine your overall ranking at the end of each eight-race season. If you're playing with a generic rider, you'll be offered or declined contract renewals with your team based on how you place at the end of each season, and you can then continue on to the next season with a new team or stay with your old team. If you're racing as one of the licensed MotoGP riders, there's no continuation between seasons. The season progression is an interesting idea, but the implementation is lacking because there's no sense of achievement whether you race a single season or five in a row. You can sign with better or worse teams depending on how you perform, but there isn't any sort of tangible difference in performance between teams. Whether you're racing in season or arcade mode, there are a variety of settings you can adjust to customize the experience. You can choose from three difficulty settings, adjust the number of laps, and choose between arcade mode and sim mode. In arcade mode, the handling of the motorcycles is forgiving, and unless you hit another rider or a wall at full speed, you don't have to worry about crashing. Sim mode is quite the opposite, and the handling on the bikes is so slippery that you can easily dump your bike on a turn if you're too heavy on the throttle. In sim mode, you can powerslide around corners, which is a technique that, if used properly, can shave seconds off your lap time. However, it's very easy to oversteer when going into a powerslide because the handling is so loose that it barely feels like your bike is making contact with the pavement. In sim mode, if you leave the track at all, you'll wreck; whereas in arcade mode, you can take a corner wide into the grass or sand without being slowed down too much. In addition to arcade and sim mode, you can turn on a brake assist, which automatically reduces your speed in corners. It definitely makes the game less technically demanding, but when it comes down to it, the determining factor of most races isn't the judicious use of gas and brake; rather, it's the line that you take through each turn. In addition to the different racing settings, you can adjust the characteristics of your bike to suit your riding style. You can trade top speed for faster acceleration, stability for handling, and so on. There are four categories to adjust, and although some of them do make a noticeable difference in the way your bike handles, it's usually not enough to influence the outcome of a race. Member Comments Add Your Comment Conversation powered by Livefyre Quick Specifications • Release date09/26/06 • ESRB Everyone • Developer Namco Bandai Games • Genre Driving • Number of players 1-8 Players
http://reviews.cnet.com/psp-games/motogp-psp/4505-10078_7-31884305.html
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Home | About | Sematext search-lucene.com search-hadoop.com  Search Hadoop and all its subprojects: Switch to Threaded View Zookeeper, mail # dev - Possible failure scenarios with deserialization + multi? Copy link to this message Possible failure scenarios with deserialization + multi? Thomas Koch 2011-10-28, 15:04 continuing with my refactorings, I think I might have found additional failure scenarios that could happen with deserialization + multi transactions. first failure scenario: MultiTxn creates two nodes, serialization sees only the first node but not the second. The zxid of the deserialized DataTree however is set to the MultiTxn, because deserialization saw the first created node and its zxid. second failure scenario: FileTxnSnapLog.restore contains a code block handling a NODEEXISTS failure during deserialization. The problem is explained there in a code comment. The code block however is only executed for a CREATE txn, not for a multiTxn containing a CREATE. second failure scenario extended: Even if the mentioned code block would also be executed for multi transactions, it needs adaption for multi transactions. What, if after the first failed transaction in a multi txn during deserialization, there would be subsequent transactions in the same multi that would also have failed? We don't know, since the first failed transaction hides the information about the remaining transactions. Thomas Koch, http://www.koch.ro
http://search-hadoop.com/m/MyOGc23skrO1&subj=Possible+failure+scenarios+with+deserialization+multi+
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Jesse Luehrs > OX > OX::Role Annotate this POD View/Report Bugs Module Version: 0.13   Source   OX::Role - declare roles for your OX applications version 0.13 package MyApp::Role::Auth; use OX::Role; has auth => ( is => 'ro', isa => 'MyApp::Auth', router as { route '/auth/login' => 'auth.login'; route '/auth/logout' => 'auth.logout'; package MyApp; use OX; with 'MyApp::Role::Auth'; has root => ( is => 'ro', isa => 'MyApp::Controller::Root', router as { route '/' => 'root.index'; This module allows you to define roles to be applied to your OX applications. OX roles can define any part of the application that an OX class can, except for middleware and declaring a pre-built router or router class. When you consume the role, all of the services, routes, and mounts will be composed into the application class. During composition, conflicts between mounts and routes will be checked for, similar to how roles normally detect conflicts between methods and attributes. If two mounts are declared with the same path, a conflict will be generated, and if two routes are declared with the same path (disregarding the names of variable path components), a conflict will also be generated. The consuming class can resolve these types of conflicts by declaring its own mount or route, respectively. If a route is declared which would be shadowed by a mount declared in another role, this generates an unresolvable conflict - you'll need to fix this in the roles themselves. Note that since the router keyword doesn't happen at compile time, you should most likely put the with statement for your application roles after the router block. router as { Sugar function for declaring coderefs. router as { router as { route '/' => 'root.index'; mount '/admin' => router as { wrap "MyApp::Middleware::Auth"; route '/' => 'admin.index'; route $path, $action_spec, %params route '/' => 'controller.index'; id => { isa => 'Int' }, name => 'view', route '/method' => 'method_controller'; route '/custom' => $my_custom_thing; template_root => 'template_root', mount '/other_app' => sub { my $env = shift; wrap 'Plack::Middleware::Static', ( root => 'static_root', This software is copyright (c) 2013 by Infinity Interactive. syntax highlighting:
http://search.cpan.org/~doy/OX/lib/OX/Role.pm
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Forgot your password? Comment: Re:Very nice.. (Score 1) 267 by SignOfZeta (#42741641) Attached to: RIM Unveils BlackBerry 10, Its Big Turnaround Hope I've never been a BB fan (never owned one) but I was given an iPhone and a BB10 beta to play with. The BB10 feels way better, and I mean waaaay better. With the iPhone it feels like you spend most of the time clicking on the menu button moving to another app. On the BB10 you swipe left or up and as if by magic all your other app(s) are there, still running. To be fair, the iPad has had those same multi-finger gestures for quite some time. For some reason, though, the iPhone never got that feature. Comment: Re:Really instead of ? (Score 1) 445 by SignOfZeta (#42610037) Attached to: UK ISP PlusNet Testing Carrier-Grade NAT Instead of IPv6 I don't know where you live, but I spoke with a surprisingly-knowledgeable Comcast representative some time ago about the future of IPv6 on their network. They are rolling it out market by market, but unfortunately for me, the northeast and mid-Atlantic states will be one of the last regions to have it activated. Something something legacy equipment up there. She couldn't provide a time frame, though it will definitely be addresses. (Whenever that may be.) If you do have it enabled, though, your router will get a single IPv6 address. If it's capable of DHCPv6-PD and you left that enabled, you'll wake up one morning to see that IPv6 has magically come to your house. Comment: Re:inevitable? (Score 1) 445 by SignOfZeta (#42609971) Attached to: UK ISP PlusNet Testing Carrier-Grade NAT Instead of IPv6 I know Charter Communications is selling only DOCSIS 3.0 modems now, but that seems to be solely for the speed benefits. However, relevant to the article, there was an extension to the old standard called "DOCSIS 2.0 + IPv6" which does exactly what you think it does. I'm not sure how popular that was, but it does exist. by SignOfZeta (#42525839) Attached to: Change the ThinkPad and It Will Die Pick up ANYTHING APPLE. It does not feel like a cheap piece of shit. Well, except for the few remaining white MacBooks. But I do see your point. Apple products aren't typically just a couple plastic housings molded, glued, screwed, or snapped together. They're glass, metal, or whatever else Jony Ive's been playing with lately. When you pick one up, it feels solid, just the right weight... and hopefully, like it's worth the price tag. Comment: Re:oh shit, (Score 1) 249 by SignOfZeta (#41929171) Attached to: Why Would a Mouse Need To Connect To the Internet? And IPv6. Granted, I hate the fact of registering hardware before it will accomplish its intended goals, but if Hardware Manufacturer A fires out 50 million mice without an IPv6 stack, they're just asking for trouble. Although, if this mouse does support IPv6, I still won't buy one. I'll just laud it for its one non-saving grace. Comment: Why not hypervisors? (Score 3, Interesting) 320 by SignOfZeta (#41849563) Attached to: Ask Slashdot: Little Boxes Around the Edge of the Data Center? I don't operate a datacenter, but for virtualized servers in an office, I always enable the NTP server functionality in the hypervisor, have it sync to a stratum-1 time source, then advertise that address via DHCP and DHCPv6 for my guests and workstations (and visiting cell phones) to use. Being the definitive time source, I also tell the hypervisor to automatically set the clock on the guests, then give a virtualized AD domain controller (if any) the PDC FSMO role to set the Windows domain time. I have sites with two or three hypervisors running NTP, and it seems to work well. Not sure if it will scale to your environment, OP, but it may be worth mulling over. Comment: Re:Darn, no mesh (Score 1) 62 by SignOfZeta (#40685663) Attached to: Contiki 2.6: IPv6 For Everything, Everywhere Just using the public IPv6 prefix given out by your router would be easier than setting up your router to hand out unique local addresses, or using link-local addressing and hoping that all of your devices are on the same physical link. Plus, it would make remote management easier, assuming your theoretical iPhone app doesn't communicate with some kind of master gateway device. An argument can easily be made for both sides in this case. Comment: Re:iOS has encryption and management built-in (Score 1) 138 If you're talking about unlocking the phone via the lock screen like people do, that's a no-go. There is an option to erase the device after ten failed unlock attempts, and (correct me if I'm wrong) it's turned on by default. Even though there are only 10,000 possible combinations, you'll only have the chance to try 0.1% of them before the phone self-destructs, no matter how long you wait between attempts. If you're talking about bypassing iOS and attacking the flash chips directly, then post a link. I'm curious. Comment: It's not there for me (Score 1) 205 They say that all FileVault (1 and 2) users on 10.7.3 are affected, so I looked at the appropriate file (apparently no one on the Internet is speaking its path and file name) and found the lines marked DEBUGLOG, but my cleartext password wasn't there. Everything else is. I'm not saying the story is untrue; I'm looking right at a bunch of lines that say DEBUGLOG. I guess I somehow got lucky.
http://slashdot.org/~SignOfZeta
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Forgot your password? Comment: Where does the money come from? (Score 3, Interesting) 223 by kullnd (#44774829) Attached to: Epic: A Privacy-Focused Web Browser From their page:: So ... They get paid for searches they drive but those searches don't have any ads or tracking? Again, where does the money come from? Comment: Re:Stop Theft Plates (Score 1) 253 by kullnd (#44216969) Attached to: Ask Slashdot: Good Tracking Solutions For Linux Laptop? Nothing is perfect - I feel that these, combined with a very clear label that states the system drive is fully encrypted (which it is), dramatically decrease the value of the system to a would-be thief whether they are looking to make a quick buck at the pawn shop or mine the system for information. They also allow for return of your equipment if you leave it somewhere or loose it outside of theft. The idea is simply that my systems are a less desirable target than most others. Never had a system stolen, but if the worst case scenario takes place I have insurance and due to the encryption and backups, I have ZERO concern about the data on the system which is where the real value lies.. Comment: Run your own servers and use encryption (Score 5, Informative) 622 by kullnd (#43986349) Attached to: Keeping Your Data Private From the NSA (And Everyone Else) Only way you can keep your data yours while sitting at rest is to have it on your own servers and utilize proper encryption and security on those servers. That means don't use "cloud" anything unless it's on equipment you own, run your own email servers, etc. Remember that even doing this, emails that you send to other people can be accessed through whatever servers they use. Comment: Re:Work for a local IT company (Score 4, Insightful) 293 by kullnd (#43930487) Attached to: Ask Slashdot: Getting Exchange and SQL Experience? Considering I was being paid $20 an hour and when the company I was working for charged $95 an hour. I do believe that there is a problem. $95/hr is split into: Your $20/hr + (Plus any benefits, Federal taxes, blah, blah) Plus the time that someone spent getting that client you just did $95 worth of work for Plus the money that was spent marketing to get that client you just did $95 worth of work for Plus the admin time that will be spent billing that client Plus dealing with the clients that don't pay Plus office rent, utilities, other office overhead that you probably have no clue about Plus tools used to perform the work (ticketing system, remote access tools?) . Again, you probably have no clue how much that actually costs Plus you were paid to drive to that client, and if using your own vehicle should have gotten mileage In addition to the drive, you are likely not billing 100% of your time anyway - Company still pays you when you are not billable right? Believe it or not, the Margin on those accounts is not that much. Does it make money? Well I hope so or your company will no longer exist - Does it make someone filthy rich? Probably not. by kullnd (#43929441) Attached to: Ask Slashdot: Getting Exchange and SQL Experience? That's a bit extreme of an example - but yes - you are failing to take into account everything that goes into running these types of operations such as Software Licensing (Which is crazy expensive for their ticketing systems and remote management tools), tools, rent, utilities, insurance (General liability and Errors / Omissions, Bonding (really good idea if you have employees in this type of business), your benefits, your payroll taxes, marketing, the cost of doing sales (i.e. not making money to get money) ... the list goes on. If you think it's such a great deal for the owner, why don't you try it yourself - It's a lot harder to get by than you think. Comment: Work for a local IT company (Score 2) 293 by kullnd (#43928923) Attached to: Ask Slashdot: Getting Exchange and SQL Experience? Work for a small IT company that provides services to small / medium businesses. Prove yourself there and get involved on as many projects as you can - You will get a ton of experience and learn more than you ever will sitting in corporate IT. It's not easy work if you are doing it right, but if experience is what you want - that is a good place to find it. Comment: Re:Legalize Bombs (Score 1) 211 by kullnd (#43463221) Attached to: Boston Officials Did Not Shut Down Cell Network After Marathon Bombing Because it's the same argument from the NRA regarding the 2nd Amendment. It doesn't stipulate "small" arms, just arms, which includes bombs. In fact, this bombing shows that it's more difficult to kill a lot of people with a bomb than with an AR-15. So, by the numbers, we should legalize bombs and outlaw the AR-15. Of course, the NRA doesn't care about numbers and I'm not sure what they care about. It's clearly not the 2nd Amendment as-written. Really? Harder to kill lots of people with a bomb? Your a special kind of stupid aren't ya?. Oklahoma City Bombing Comment: Re:Legalize Bombs (Score 1) 211 by kullnd (#43461263) Attached to: Boston Officials Did Not Shut Down Cell Network After Marathon Bombing Why would they need to? Bombs are illegal, they are going to likely stay that way - But that didn't stop the criminal did it, apparently the person who did this didn't care that a law prevented him/her from having a bomb. I doubt that a sign on the street saying "bomb free zone" would have helped either, just saying. Comment: Really? (Score 4, Insightful) 101 by kullnd (#42717561) Attached to: UK Apple Users Sue Google Over Safari Tracking Maybe Google should start charging us for their services that we get for free... They have to make their money from something, if you don't like it don't use it. Also, anyone who honestly believes that a toggle in their browser is going to prevent them from being tracked on the open internet needs an education on how things really work in the real digital world. Comment: Re:Too much of a good thing? (Score 2) 82 by kullnd (#41818101) Attached to: An Open Standard For Wireless Charging? This is one of my favorite features of the ThinkPad ... As a reseller, I generally set all of my clients systems to start at about 90-93% to prevent the 1% charge cycles.
http://slashdot.org/~kullnd
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The 2013 Lib Tech Downtown Throwdown (image 16 of 20) Brendan Gerard hates jocks but loves Red Bull. What would really be cool is if he was drinking a creatine shake as he was hiking the rail jam. Photos and captions by Tim Zimmerman This past weekend Lib Tech held their annual Downtown Throwdown in beautiful Minneapolis, Minnesota. In past the Downtown Throwdown was held in Seattle, and San Francisco, but this year it was time for a change. The powers that be put their thinking caps on and came up with hosting it in Minneapolis, and what better city to host the event than the city where the majority of the new rail riders live. Everyone came out to ride. Riders like Jonas Michilot, Jake OE, Ryan Paul, and Jesse Paul all came out to ride some of Snowboy Productions infamous steel. At the end of the day the results were as follows: 1.Ryan Paul 2. Nial Romanek 3. Aidan Flanagan 4. Ted Borland 5. Jaeger Bailey Check out the photo gallery above to see all the action that you missed by not going to the Lib Tech Downtown Throwdown. Jesse Paul. PHOTO: Tim Zimmerman
http://snowboarding.transworld.net/1000211774/photos/2013-lib-tech-downtown-throwdown/?pid=53568
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Skip to the content "I hope The Magazine is a surprise every two weeks and that my column is something readers have never seen before. It should add up to something meaningful, whether you just get a big laugh out of it, or it makes you mad enough to write a letter. I never want it to be just about sports." Rick Reilly
http://sports.espn.go.com/espnmag/archive?name=reilly_rick
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Extra MustardSI On CampusFantasyPhoto GalleriesSwimsuitVideoFanNationSI KidsTNT What we learned Tourney drama alive and well; Heels show toughness Posted: Saturday March 17, 2007 11:55PM; Updated: Saturday March 17, 2007 11:55PM Free E-mail AlertsE-mail ThisPrint ThisSave ThisMost PopularRSS Aggregators Jermaine Beal (left), Shan Foster and Vanderbilt beat Washington State in double overtime, one of three OT games Saturday. Jed Jacobsohn/Getty Images SI Writers at the Tournament WAHL: Drama alive and well and more lessons DAVIS: Overtimes galore in an historic third day WINN: Pitt shows its depth in ousting VCU in OT WINN: Patience, poise carry Butler past Maryland WINN: Follow the action with the '07 Tourney Blog MANDEL: Despite Oden's struggles, OSU advances MANDEL: Louisville's Sosa falls short in career day TAYLOR: Byars, Foster power Vanderbilt in thriller DORTCH: Sans mask, Hansbrough regains his form DORTCH: G'town downs Boston College in slugfest GALLERY: Best shots from Day 3 at the Big Dance March Madness Archive | Women's Tournament Tourney Home Page | Play our Bracket Challenge Grant Wahl will periodically answer questions from SI.com users in his mailbag. Your name: Your e-mail address: Your home town: Enter your question: WINSTON-SALEM, N.C. -- Five things we learned on the day Gus Johnson finally started sounding like A.C. Green on his wedding night: 1. The NCAA tournament still provides the most compelling drama in American sports. The 'Bag can't begin to describe how depressed we were on Thursday and Friday as the top seeds won almost every game by a huge margin. Thankfully, Saturday went a long way toward making up for it. Overtime games galore, No. 1 seeds on the ropes, star players acting like it: It was exhilarating for fans (and, yes, media types). If you didn't enjoy Saturday's games, you weren't alive. 2. Xavier should have fouled at the end of regulation. It's hard to criticize Xavier coach Sean Miller after his team played such a sensational game against Ohio State, but the 'Bag can't understand why Xavier didn't foul an Ohio State player before Ron Lewis squeezed off his game-tying three-pointer at the end of regulation. Coaches are often control freaks to their detriment in the final seconds -- witness anybody who calls timeout when an opponent goes up by one with six seconds left instead of attacking an unset defense -- but Miller should have asserted his control and told his players to foul. The only bad things that can happen are 1) your guy is dumb and fouls too late, letting his man get into his shooting motion and draw three free throws, or 2) the free-throw shooter makes his first and misses his second on purpose to create a put-back offensive rebound. Let's be honest: What are the chances of those two scenarios happening? Not good at all. What are the chances of Lewis hitting a game-tying three? A lot better. Why Miller didn't have his guys foul OSU is beyond me. 3. North Carolina isn't soft after all. Remember when Marcus Ginyard was questioning his teammates' toughness a few weeks ago? He was right: the Tar Heels weren't getting to loose balls, weren't fighting for rebounds, weren't giving the impression that they'd fare well against an a**-kicking team like Michigan State. Well, there were those same Heels on Saturday toughing out an 81-67 win against the Spartans by three in the second half. Reyshawn Terry fought off excruciating migraines and got some big baskets down the stretch, while Tyler Hansbrough scored 33 big ones, went to the line 17 times and even got banged in the face (without extra damage) after abandoning his fright mask. So maybe Brandan Wright (three points, seven boards) still struggles against tough teams, but Carolina has plenty of other answers. We can't wait for a UNC-Texas showdown if the Longhorns can take down USC on Sunday. 4. Roy Hibbert has nerves of steel. The 'Bag has a man crush on Hibbert, the 7-foot-2 gentle giant who reminds us more of a plant-eating brontosaurus than a carnivorous T-Rex. We're OK with that, though. Hibbert has a sixth-sense that tells him exactly when the shot clock will go off, which explains his ability to hit two huge buckets in crunch time (both of them in the shot clock's dying seconds) and feather a gorgeous interior pass to Pat Ewing Jr. for the and-1 that put away Boston College. 5. The mid-majors are doing just fine. With so few upsets this year you'd get the sense that last year's mid-major block party isn't repeating itself. But look again. More mid-majors grabbed higher seeds this year (see No. 5 seed Butler and No. 4 seed Southern Illinois), and it's still entirely possible that we could have as many true mid-majors in the Sweet 16 this year (four) as we did in last year's Mid-Major Tourney of All-Time: Butler, which is already in after a stellar takedown of Maryland; SIU, which is a heck of a lot more consistent than upcoming foe Virginia Tech; Winthrop, which has a solid chance to sink Oregon; and Nevada, which the 'Bag has a hunch will beat Memphis. As Wichita State alum (and Singles cameo stud) Xavier McDaniel pointed out last year, folks: The mid-majors are still coming. Sports Illustrated senior writer Grant Wahl covers college basketball for the magazine and SI.com.
http://sportsillustrated.cnn.com/2007/writers/grant_wahl/03/17/five.things.saturday/index.html
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Take the 2-minute tour × What's the most efficient way to concatenate strings? share|improve this question add comment 11 Answers up vote 49 down vote accepted StringBuilder sb = new StringBuilder(); share|improve this answer Isn't the 'ToString' call on 'someString' unnecessary? Unless 'someString' is really an int, and it's a big lying liar. ;) –  Sarah Vessels Jun 25 '09 at 13:44 funny, but good point :) –  TheEmirOfGroofunkistan Jun 30 '09 at 20:28 It would be good to note that though String.Join adds a delimiter, you can make that delimiter String.Empty. –  Ryan Versaw Jun 30 '09 at 21:11 StringBuilder has a huge comparable start-up cost, it's only efficient when used with very large strings, or very many concatenations. It isn't trivial to find out for any given situation. If performance is of issue, profiling is your friend (check ANTS). –  Abel Nov 4 '09 at 13:22 This is not true for single line concatenation. Say you do myString = "foo" + var1 + "bar" + var2 + "hello" + var3 + "world", the compiler automatically turns that into a string.concat call, which is as efficient as it gets. This answer is incorrect, there are plenty of better answers to choose from –  csauve Jan 12 '11 at 17:56 show 4 more comments Rico Mariani, the .NET Performance guru, had an article on this very subject. It's not as simple as one might suspect. The basic advice is this: If your pattern looks like: x = f1(...) + f2(...) + f3(...) + f4(...) that's one concat and it's zippy, StringBuilder probably won't help. If your pattern looks like: if (...) x += f1(...) if (...) x += f2(...) if (...) x += f3(...) if (...) x += f4(...) then you probably want StringBuilder. share|improve this answer This answer is the correct one, not the answer by "TheImirOfGroofunkistan" as that does not take into account single-line concats. –  csauve Jan 12 '11 at 17:58 +1 I didn't know that :) Neither of my books mentions that. Thanks, I'm really used to single line +'s syntax –  surfen Jan 9 '12 at 23:49 add comment From Chinh Do - StringBuilder is not always faster: Rules of Thumb • When concatenating three dynamic string values or less, use traditional string concatenation. • When concatenating more than three dynamic string values, use StringBuilder. • When building a big string from several string literals, use either the @ string literal or the inline + operator. Most of the time StringBuilder is your best bet, but there are cases as shown in that post that you should at least think about each situation. share|improve this answer afaik @ only turns off escape sequences processing. msdn.microsoft.com/en-us/library/362314fe.aspx agree –  abatishchev Jul 18 '10 at 20:11 add comment If you're operating in a loop, StringBuilder is probably the way to go; it saves you the overhead of creating new strings regularly. In code that'll only run once, though, String.Concat is probably fine. However, Rico Mariani (.NET optimization guru) made up a quiz in which he stated at the end that, in most cases, he recommends String.Format. share|improve this answer I've been recommending the use of string.format over string + string for years to people I've worked with. I think the readability advantages are an additional advantage beyond the performance benefit. –  Scott A. Lawrence Nov 14 '08 at 18:38 This is the actual correct answer. The currently accepted answer for StringBuilder is incorrect, as it does not mention single line appends for which string.concat or + is faster. Little known fact is that the compiler actually translates +'s into string.concat's. Also, for loops or for multiple line concats I use a custom built string builder that only appends when .ToString is called - overcoming the indeterminate buffer problem that StringBuilder has –  csauve Jan 12 '11 at 17:53 add comment There are 5 types of string concatenations: 1. using plus (+) symbol. 2. using string.Concat(). 3. using string.Format(). 4. using string.Append(). 5. using stringBuilder. In an experiment, it has been proved that string.Concat() is the best way to approach if the strings are less than 1000(approximately) and if the strings are more than 1000 then stringBuilder should be used. For more information, check this site. share|improve this answer Whilst this may theoretically answer the question, it would be preferable to include the essential parts of the answer here, and provide the link for reference. –  Shawn Chin Sep 4 '12 at 8:23 i am new to .net, while referring this question i also got this link through google search. so i just forwarded here thinking it may help others. –  Mr_Green Sep 4 '12 at 8:40 If that page goes down, your answer would no longer be useful. However, if you include essential parts of the answer in your post here and link to that page then not only will your answer be always valid, but it will also be another page which google search can index to help other readers. That is the main reason why we encourage people to avoid link-only answers. –  Shawn Chin Sep 4 '12 at 8:48 I have edited the answer. :) –  Mr_Green Sep 4 '12 at 9:00 Thanks. I've formatted it so it's easier to read. –  Shawn Chin Sep 4 '12 at 9:13 show 5 more comments From this MSDN article: So if you trust MSDN go with StringBuilder if you have to do more than 10 strings operations/concatenations - otherwise simple string concat with '+' is fine. Simple and sound, if - I repeat - you decide to trust MSDN. share|improve this answer add comment The most efficient is to use StringBuilder, like so: StringBuilder sb = new StringBuilder(); String strResult = sb.ToString(); @jonezy: String.Concat is fine if you have a couple of small things. But if you're concatenating megabytes of data, your program will likely tank. share|improve this answer add comment It would depend on the code. StringBuilder is more efficient generally, but if you're only concatenating a few strings and doing it all in one line, code optimizations will likely take care of it for you. It's important to think about how the code looks too: for larger sets StringBuilder will make it easier to read, for small ones StringBuilder will just add needless clutter. share|improve this answer add comment It really depends on your usage pattern. A detailed benchmark between string.Join, string,Concat and string.Format can be found here: String.Format Isn't Suitable for Intensive Logging (This is actually the same answer I gave to this question) share|improve this answer add comment For just two strings, you definitely do not want to use StringBuilder. There is some threshold above which the StringBuilder overhead is less than the overhead of allocating multiple strings. So, for more that 2-3 strings, use DannySmurf's code. Otherwise, just use the + operator. share|improve this answer add comment It's also important to point it out that you should use the + operator if you are concatenating string literals. When you concatenate string literals or string constants by using the + operator, the compiler creates a single string. No run time concatenation occurs. How to: Concatenate Multiple Strings (C# Programming Guide) share|improve this answer add comment Your Answer
http://stackoverflow.com/questions/21078/whats-the-best-string-concatenation-method-using-c
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Left 4 Dead 2 > Általános témák > Téma részletei The Actual Heavy jan. 30. @ de. 6:29 I'm really bad at this game. . . but would like to improve I'm wondering if anyone has any tips for getting better at this game. I'm good at FPS games in general, but for some reason this particular game just kicks my butt. I think it's the extremely fast pace of the hoards, I just get overwhelmed easily. Any tips/tricks? 115/20 megjegyzés mutatása < > Panda jan. 30. @ de. 7:03  Luxius jan. 30. @ de. 7:45  Not much, just like everything: the more you train, the better you get. It's better if you learn on your own just take your time. RΞV [A] StonedBooM jan. 30. @ de. 7:51  Remember to slap the witch Pepekiller jan. 30. @ de. 8:05  jugar jugar y jugar. a mi antes tambien me parecia super rapido pero hoy e agunatado 6 ordas con un compañero. en este me estoy haciendo un jugador muy bueno en el modo experto The Actual Heavy jan. 30. @ de. 8:06  Ingles, por favor. snafu jan. 30. @ de. 8:11  hi all i can say is just enloy the game on easy and the go forward with the enjoyment hehehehehe is just a good fun game loads of laughs Womble jan. 30. @ de. 9:34  shoot ->slap--->shoot--->slap learn to know the spit voice and the warnings. help your teammates. stay together PoopNowMexicanRobot jan. 30. @ de. 9:58  Bless you for wanting advice and not just crying about getting kicked and how ♥♥♥♥unfair the community is. If only others follow your example. SInce you should already be able to aim heres my best advice: Turn full captions on so even if you dont hear the sound effects for an incoming horde, infected spawn/attack/death, tank music, ect you still know whats happening and can be ready. This varies based on what weapons you use but aim where theres the most meat and go for Mid to Upper torso. Nothing wrong with headshots but with the pace of the game youll clear more horde this way. Most zombies are dead before you realize it. A good 2-3 shots to the torso will take out most zombies. Some go down instantly and others will continue to walk and stagger for several seconds. Learning and trusting your aim will allow you to know its dead whether its down or not and move your crosshairs else where much quicker and waste less ammo. Melee is your BEST FRIEND. As someone else said if youre surrounded melee the zombies back and then shoot them. If you have them all around you a melee will shove the zombies back enough to give you a few seconds before they're back on you giving you time to melee the ones behind and turn back around to kill the ones in front and switch back and kill the back before either is able to hit you again(hopefully that wasnt too confusing). As far as DeadStopping hunters and jockeys the time you think you should melee to stop them is about a second off if not more. That just takes practice getting down the timing as for when to melee. Once you get that down skeeting is just having a shot where the hunter will be timed right before the melee to deadstop. That way if the shot fails you'll still deadstop it. For crowning a witch just go all the way up to her if she is sitting. Literally bump into her then aim between upper torso/neck/lowerhead and you'll be good except for expert. For the walking witch almost same thing but shoot right before you're about to bump into her in the same area. Forget Bilebombs in general unless you just want to sit and shoot at a pile. jordant94 jan. 30. @ de. 10:01  your probs not really bad, the community will make you thinku are and kick you all the time.. oh welcome to l4d2.. ♥♥♥♥tiest community ever lmao ~{ Val }~ jan. 30. @ du. 1:23  Well, just play afew more times and you'll be fine. First start off in easy mode, then move up a level when you feel that you are ok with it. The following are some of the things that i'll usually do, so you may want to take note of it: 1) Always stick to the group, as if you are getting pin by hunter, grab by smoker, you'll need another player's help to knock them off. So wherever you go, make sure that there is at least 1 other player with u. (unless you become a pro, then ....) 2) When hords of zombies start to swarm, it's best to lean again a corner of a room. As, if you are standing in the center, they can attack from all direction. Being at a corner, you only need to defend a 90 degree angle, so it's easier. 3) In terms of weapon, my personal habbit is, having at least 1 weapon that can at least hit a middle range target. As guns like shotgun are only good for close to short range, you can barely hit anything with it on a mid to long range. So it's good that if you pri weapon is shotgun, let you sec weapon be a pistol/magnum instead of a melee weapon. 4) In terms of guns, for new player it's more recommanded that you stick to assult rifles, as it's more easier to use as a starter. And personally, it's so far the best weapon type again other players. As in my years of playing this game, i have encounter quite afew people that start shooting everyone in the team for no reason. And I have to put them down. Super Genius jan. 30. @ du. 5:45  UnderMySoul jan. 30. @ du. 5:48  Try all the weapons and find the one you like best. I always keep a melee weapon on me. A melee weapon is especially nice for some of those hoards. If your health is low and the hoard is thick get in a corner with the melee weapon. The katana (sword) and axe work nicely. Paranoid jan. 30. @ du. 6:54  If you can afford it, invest in a 7.1 Surrond sound headset. I think sound is key in the game. Once you know what sounds are what, you will know, for instance, when a team mate is being attacked even before they can call out to you. You'll be able to hear the special infected around corners, behind you and from all different directions. You'll be able to hear the tank growling ahead of you, so you know to be prepared. I use the Logitech g930. These days they're running about $120ish. Amazing sound quality for the price. Revenant jan. 31. @ de. 6:47  One piece of advice that I found most helpful in learning with L4d1 and is starting to work with L4D2 is the following: Play Single Player on every campaign first. Play Campaign online in every campaign after that. This is where you will make friends - eventually. These people help you learn and grow during the game. After you have completed that - Versus mode is where the hardcore action is in my opinion. Though there is many other modes - Mutations, realism, e.t.c. Versus is where most players seem to find the fun - IF they know the maps. See you around, 115/20 megjegyzés mutatása < > Laponként: 15 30 50 Küldés ideje: jan. 30. @ de. 6:29 Hozzászólások: 20
http://steamcommunity.com/app/550/discussions/0/864958451268712451/?l=hungarian
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Brand New are an AlternativeRock band from Long Island, New York. The band was founded in 2000 and has released four studio albums. Their style is a mixture of Alt Rock, {{Emo}}, PopPunk, and {{Post-Hardcore}}. '''Their lineup consists of:''' * Jesse Lacey- vocals, guitar * Vincent Accardi- lead guitar, backing vocals * Brian Lane- drums * Garrett Tierney- bass * Derrick Sherman- keyboards, guitar, backing vocals '''Their discography includes:''' * ''Your Favorite Weapon'' (2001) * ''Deja Entendu'' (2003) * ''The Devil And God Are Raging Inside Me'' (2006) * ''Daisy'' (2009) !This band leaks examples of: * ADateWithRosiePalms: The song "Magazines" is a bit of this. * BreakUpSong - Most of ''Your Favorite Weapon''. ** And the entirety of "The Boy Who Blocked His Own Shot." ** "Seventy Times 7" is a particularly spiteful "between friends" version. * BilingualBonus: Deja Entendu is French for 'already heard'. A joke about how they said they don't want to make the most original music, just good music. ** It's also called this because the entire album is a biting, critical {{Deconstruction}} of rock cliches both past and present. * CarefulWithThatAxe - "Luca" is a particularly alarming instance. * DarkerAndEdgier - A career-long shift, from the relatively upbeat-sounding relationship songs of ''Your Favorite Weapon'' to the emo-tinged ''Deja Entendu'' to ''The Devil and God Are Raging Inside Me'' which was their darkest yet. Then, ''Daisy'' was released and it took this even further, albeit in a different way (''The Devil and God'' was raw, heavy, and angry, while ''Daisy'' is lighter, but even creepier). * {{Deconstruction}}: On almost all of its tracks, ''Deja Entendu'' deconstructs several different rock music cliches by taking all of the glamour out of them and exposing them for what they really are. This theme of applying real world logic to these age-old cliches permeates the album. A few of the biggest examples are as follows: ** ''Sic Transit Gloria'': A SexAsRiteOfPassage song that portrays the much heralded loss of virginity as anything but glamorous. ** ''I Will Play My Game Beneath The Spin Light'': A look at the less exciting parts of the life of being a rock musician and how it can take its toll on a person. ** ''Okay I Believe You But My Tommy Gun Don't'': A song in which Jesse Lacey basically outlines every single message that rock musicians sing about while both subtly tearing them down and acknowledging that he plays a part in these messages. ** ''The Quiet Things That No One Ever Knows'': An AntiLoveSong about how storybook romances don't exist and that romances that seem like storybook romances can end in boredom and sadness. ** ''Me vs. Maradona vs. Elvis'': a skin-crawling IntercourseWithYou that portrays the act of picking up women that rock music so often glamorizes as empty, creepy and manipulative. * KidsRock- The creepy choir in "Degausser". * LongTitle: ''The Devil and God Are Raging Inside Me'' ** Most of the tracks on Deja Entendu, the longest being ''Good to Know That If I Ever Need Attention All I Have to Do Is Die''. * MurderBallad - "Luca", which describes a mafia execution and is a ShoutOut to Film/TheGodfather. * MoodWhiplash: Jesus Christ, Luca. ---> ''Website/YouTube commenter'': "this song put me to sleep - then it woke me up." * PurpleProse - Jesse's preferred lyrical style. It's a wonder how he can fit some of these lines to music. * TakeThat - Your Favorite Weapon is full of shots against TakingBackSunday, Jesse's former band. * SexAsARiteOfPassage - "Sic Transit Gloria" is a darker take on this. * StudioChatter - "Soco Amaretto Lime" has "one, two, three, four," in the beginning, albeit very, very faintly. ** Jesse can be heard saying "yeah, that's right" and starting the countdown at the beginning of "Play Crack the Sky." You can also clearly hear him put down his guitar and walk away at the end of the song.
http://tvtropes.org/pmwiki/folderizer.php?target=Music.BrandNew
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main index Topical Tropes Other Categories TV Tropes Org Speaks In Binary Pit: "Does something seem a little... off with Pyrrhon?" Palutena: "How can you tell?" Pyrrhon: "01001011010010010100110001001100." Binary code: The base-2 number system. Occasionally known as the "language" of computers. However, it's not usually spoken. But when it is, it's this trope. It's usually used jokingly as robots "native" language. However, "binary" is not a language: Raw binary data has no meaning without a structure describing what it is. The "binary language" could be anything from "English text encoded in ASCII" to "Ideas, each attributed to a 16-bit number". Compare Speaks in Shout-Outs, where a character speaks almost exclusively in reference to other works. Anime and Manga • Robots in Masamune Shirow's work (Ghost in the Shell, Appleseed) often do something very similar: speaking in bar codes! • The old modem like chirping emitted by droids in Star Wars films is called "binary" in-universe. However, it's unknown whether it's binary as we know it and how is it encoded into sound. • Ashley, and all the other aliens, in Jasper Fforde's Nursery Crime series have binary as their native language. They also play binary Scrabble. Live-Action Television Newspaper Comics Tabletop Games Video Games • In Mass Effect 1, the final message from the rogue AI on the Luna Base is in binary. It translates into "HELP". • When Pyrrhon from Kid Icarus: Uprising tries to control the Aurum, only for them to take control of him, he speaks out loud in binary; it translates to "KILL". • Volt in Tales of Phantasianote  speaks almost entirely in binary, causing a misunderstanding between him and the heroes which leads to a fight, and later, a contract. Web Comics Web Original • Pirate_Tinman in the Yogscast Minecraft Series speaks in binary because his actual voice is broken, as shown when he first booted up in The Shadows of Israphel. This is used to call the duo idiots behind their back at some points. • SFDebris makes this joke in this review of StarTrekVoyager episode "The Killing Game". A Borg "love song" sung by Chuck!Seven is in binary with a hexadecimal verse. Western Animation • In Futurama, Bender says a prayer in binary. He ends with "2". • There's also the Time Code from Bender's Big Score, a long list of zeros and ones that is said like an incantation to send the speaker back in time. • In "Godfellas", the galaxy that may or may not be God signals Bender in binary. Bender mentions that he only knows enough binary to ask where the bathroom is (which contradicts the above, but hey, Rule of Funny). • In an episode of ReBoot where the Plucky Comic Relief told a joke in binary; the "binary joke" comes out to "Take my wife, please!" when translated into ASCII. Speaking SimlishLanguage TropesSpeaks in Shout-Outs Permissions beyond the scope of this license may be available from Privacy Policy
http://tvtropes.org/pmwiki/pmwiki.php/Main/SpeaksInBinary
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The World of Pekab is now licensed under Creative Commons The Feldjäger are the Military Police of the Prussian Empire’s army, and as such, their job is to prosecute those who fall foul of military law, usually through summary execution. Their duties also include security, and again, this is usually enforced through summary execution. In fact, everything they do is enforced through summary execution. It is little wonder they are not particularly liked within the army of the Prussian Empire. Feldjäger Soldat General Gunter Grass General Gunter Grass has served in the army of the Prussian Empire for twenty years, and as such, has just about seen it all. He has served in all infantry regiments, and has even done a stint in the Feldjager, or military police. He is currently serving as commander of the Prussian Empire’s Ekk Korps, a regiment of Panzergrenadier (mechanized infantry) that has extensive desert combat experience. The Ekk Korps are currently based in Aegyptus, as the Prussian Empire desires to get their mitts on some of the Pharaoh’s treasures before Blighty does (cue Indiana Jones-esque plot devices here). The current Pharaoh, Cleopatra, is not keen on his presence in her country, but without a decent army, there is not a lot she can do about it. She will just have to hope that the few MI7 agents from Blighty, and ASAG, can do something about it for her. Waldhuter Unteroffizier Waldhuter Soldat Waldhuter Panzeerfaust Squadron Formation Von Braun Von Braun left the Anarcho-Syndicalist Adventurers Guild when his squad was disbanded. So he returned home and looked up his old friend, Gunter Grass, who offered him a job in the Ekk Korps. He persuaded Viktoria to come with him. Viktoria was formerly a Sharp Shooter within the Anarcho-Syndicalist Adventurer’s Guild before leaving when her squad was disbanded somewhat unceremoniously. Now she has signed up for a stint with the Prussian Empire‘s Ekk Korps, despite being from the Soviet Rusk Republic. Von Braun had quite a lot to do with this, as it was his suggestion that she’d try her luck with the Prussian Army. Modifications, Alterations, and general news stuff… As you can see, I have heavily altered the army list for ASAG (Anarcho-Syndicalist Adventurers Guild) and dropped two whole squads out of it. Also, both Anne Casey’s and Clint’s squads have been altered. Caesar has moved to Anne’s squad and Clint’s squad has been reduced to four while I change a figure around and create a new card for him. This is to free up minifigs, get rid of those God-awful quads, and assign certain minifigs to the Prussian Empire force I am currently trying to build up. I have received the truck and jeep set from Lego Indiana Jones and am awaiting the motorcycle set from the same series (The Last Crusade). You can still find Lego Indiana Jones sets on ebay for reasonable prices if you look hard enough. I am also waiting for the Lego minifig of Irina from The Crystal Skull to arrive in the post. I will also be doing a Bricklink order via for tan Stahlhelms, MP40′s, MG34′s, an Afrika Korps Lieutenant, and various other bits and pieces towards the middle of the month. The plan is for “Irina” to become a sidecar gunner with a MG32 with an Afrika Korps driver from Indiana Jones, another IJ German to ride the other bike, the Afrika Korps Lieutenant to ride the back of the “jeep” with its gun being replaced by another MG34 (the original Lego one is pretty crap), and make up a motorized “Afrika Korps” type squad or two out of this. MI7 now numbers 8 minifigs, and they will all be written up in due course. I have also been collecting the Mining range from Lego City, and that will be a new faction in the not too distant future. I have put together a small defence force for it, including a hero and driver in a MOC muscle car based loosely on the sports car from Pharaoh’s Quest. Another faction I am working on is an Aegyptian Army based on the Pharaoh’s Quest sets. I have recently obtained Cleopatra from the Minifig Series, and she will be the hero for that faction. I could do with many more mummies and some of those Anubis Guard to add to that force… Anne Casey’s Squad Anne Casey Clint’s Squad He shoots big guns and is painfully polite around ladies. Evie’s Squad (RMRS) Evie is unkempt, unshaven, and a bit of a speed freak. He is also the best thing you have seen on two wheels. Evie is often tanked up on coffee, and is terrible at getting up in the mornings. Evie now heads up the first Rapid Motorised Reaction Squad. Natalia recently got hired by the Anarcho-Syndicalist Adventurers Guild on the recommendation of Evie. His colleagues are unsure whether it was because of her coffee, or because of her ability with explosives. Natalia, for her part, keeps quiet about this. She has her eye on Evie – now if only he would shower a bit more often… Yvonne is not one to be underestimated at all – smart, sassy, and very very tough. She has been on the saddle of bikes, trikes and quads since she was knee-high to a halfling, and there isn’t a Steel Horse that she cannot handle. Smith Senior Smith Senior is Grunge Smith’s father, a curmudgeonly old explorer who still has plenty of life left within him. Ian is a hot-headed young punk who seems to think that his trike is a mobile weapons platform. After strapping an M1919 to the back few would now argue with his insistence that it is. Get every new post delivered to your Inbox. Join 7,956 other followers
http://worldofpekab.wordpress.com/
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Joe Kukura Report New Story 1,868,016 Total Views January 2012 Profile Views: 66,501 Total Reports: 523 Total Comments: 3 Overall Ratings: 987 JoeKukura's viewers this month have come from the following countries: USA: (80.0%) Canada: (4.4%) United Kingdom: (2.1%) India: (1.4%) Germany: (1.1%) Australia: (1.1%) China: (0.9%) South Africa: (0.9%) Israel: (0.9%) 103 other countries: (6.4%) Home Page Badge Home Page This user's reports have appeared on the home page 18 times over the past 30 days. Reader Badge Readers are earning the trust of the Allvoices community. Social Media Badge Social Media This user's reports have been Liked or Retweeted 1,345 times over the past 30 days. 1 of 17 1 of 3 Sorry, there's nothing here! Cell phone carriers profit from phone theft, and want to keep it that way How Facebook video ads challenge TV and YouTube Facebook is adding those horrible 'autoplay' video ads Federal judge rules NSA spying unconstitutional Gmail to automatically display images: Death knell or jackpot for email marketers? Sprint trying to buy T-Mobile: What happens if I have T-Mobile? Three-day Yahoo Mail outage brings down Flickr too HBO fires up an 'Internet roast' of King Joffrey on Twitter Spotify adds the entire Led Zeppelin library How the NSA spying program also does lots of nice things for charity Riled up protesters block Google employee bus in San Francisco Why jewelry ads are taking over NFL games Microsoft beefing up encryption to thwart NSA snooping Liquid Plumr gets sexy with free 2014 'hunky plumber' calendar Woman gets traffic ticket for driving with Google Glass. She's fighting it Walmart caught selling counterfeit Banksy art Microsoft developing a bra that prevents overeating Xbox One, PS4 problems: People are uploading dirty videos The best #WalmartFights pics and videos on Twitter and YouTube How to watch the Macy's Thanksgiving Parade live online Length of flight delay during Thanksgiving week may depend on airline These smart aleck adults made kids' Thanksgiving hand turkeys. Their results are hilarious Yahoo exec writes unhinged email scolding employees for not using Yahoo Mail Beastie Boys fight for their right to block Goldieblox 'Girls' video unveils top 10 most-asked questions of 2013 FCC to propose letting you use your cell phone during flights Watch Channing Tatum spoof the Van Damme 'Epic Split'. What happens is nuts There will be Cinnabon vodka this holiday season Ashton Kutcher is in an epic Twitter feud with Walmart Hackers dazzle YouTube with 'How to Open a Can without a Can Opener' video
http://www.allvoices.com/users/JoeKukura
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Mini or full 4x5? I had a mini and it was "fun" kinda.... It just isn't all that great having to unfold out the bellows, composing, using the RF if it works, etc before taking a shot. With the Mamiya, the lens is there (no folding out or anything) and all you need to do is RF and cock the shutter. Done. The 4x5 is like the mini only more obtuse. I'm thoroughly amazed that Press cameras such as those were used for so long and so succesfully, seeing as though the Mamiya or even the Graflex XL press cameras are sooo much easier to handhold and frankly aren't a breakthrough in camera technology. Both will work. Both have great lenses, multiple backs, ect. Tough call.
http://www.apug.org/forums/viewpost.php?p=1166181
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or Connect AVS › AVS Forum › Display Devices › Screens › DIY Screen Section › Is Hot Spotting All Bad? New Posts  All Forums:Forum Nav: Is Hot Spotting All Bad? post #1 of 2 Thread Starter  I know, I know,: heresy. Seriously though, is it possible there is a place for a screen with some hot spotting? Please don't flame me; I'm really just trying to figure a few things out before I go with my next screen. Hopefully I can tap into greater knowledge and expertise than I have. Situation 1: Insufficient lumens for a given size screen. This is why people go with a high gain screen. Increase gain enough and you're going to limit the viewing cone. That's obvious. But is that all bad? What if all viewing takes place within that cone? Do we really care that we've limited the viewing cone? Now, a noticeably bright spot in the center of the screen is a worst case scenario, at least it seems to me. But for some people, might that be preferable to a screen that was uniformly too dim? Obviously not the best solution. But possibly the best solution available given limited funds? (ie, a brighter PJ might be very expensive) Is it a reasonable trade off for a larger screen? Situation 2: Ambient light rejection. In my theater, most ambient light comes from the side of the screen, at an angle of around 70 to 80 degrees. I put up a sintra screen, and even though it was white, I noticed the ambient light capabilities were actually quite good, for sports at least. (Which is the only ambient light viewing I do.) Recently I eyeball tested a sintra panel and a C&S panel against my SF HG screen. The Sintra was the brightest when viewed dead on, followed by the SF then the C&S. The Sintra hot spotted worse than the SF which hot spotted worse than the C&S. But it got me thinking. The Sintra was brighter than either paint when viewed dead on. As I moved to the side, outside my normal viewing position, the sintra became less bright than the C&S. At around 60 to 70 degrees, the sintra was darker than the C&S., by a pretty good margin. It seems to me that sintra's rejection of light from the extreme angle is why it performed so well for me in my ambient light scenario. I'm not trying to say I know more than the experts here, quite the opposite. I'm looking for information and opinions from those experts so that I may better inform myself. My idea is this: Is it possible to paint a sintra screen with something thin or translucent--leaving it white--enough to tame it's visible hot spot, but leave some of it's rejection of light from extreme angles? (I know it's not really rejecting it, just not reflecting it mostly in the direction of the viewer.) All of my movie watching is done in zero ambient light, so I'm just trying to get enough ambient light capability for sports. The bare sintra was fine for that, but the visible hot spot was too severe for watching movies. BTW, I'm posting this on two forums so that I can gain the widest possible perspective. post #2 of 2 i think that pj uniformity plays an important role... and given a unity to high gain screen... there will always be a warmer center area that's slightly warmer than the edges. one of the things silver screens can do is to bring out the deficiences of the source equipment and low quality media. i think though... a screen sample can be deceiving though... because our eyes focus on the brightness of the sample rather than it's contrast. it think you'd be a good candidate to go lighter... possibly rs-maxxmudd ll would be the way to go. New Posts  All Forums:Forum Nav:   Return Home   Back to Forum: DIY Screen Section
http://www.avsforum.com/t/1362929/is-hot-spotting-all-bad
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For how long after the executor (or appointed administrator)of an estate fails to perform his legal duties can he still be sued? Asked over 1 year ago - Belmont, CA Since my father's death,I have been provided with such sparse and contradictory information regarding the specifics of how my father's estate may have been eventually executed or administered,that to this day ,I am still not certain who my father named as the executor,wether several executors were named,or wether a court appointed an admistrator, after maybe deciding that my father's will could not be executed because it was only a copy ,and the original could not be found.The reason for this is that noone,even six years after my father's death,has offered to let me read the copy of his will.It seem that the copy of the will might be in the posession of my father's long time girlfriend.(I was told this by my mother,who previously had led me to believe that my father had left no will). Attorney answers (2) 1. Pro Contributor Level 12 Lawyers agree Answered . You can check with the Probate Court in the county where your father resided to see if a will was probated. Six years is quite a long time to start taking action, so it may prove more difficult to get the answers you seek. You likely have some right so the best idea is to find a probate attorney who can start working on these issues for you. There could be some serious repercussions for an executor if you were entitled to assets and never informed you. 2. Contributor Level 7 Answered . If your father's estate was probated, the probate court in the county where he resided or the county where he owned real property will have all the records including the will. Anyone can look at the court files as they are public records. Even if the will was not probated, the original was required to be filed with the County and would then become a public record. If the original was lost, there are procedures in place where a copy can sometimes be substituted for the original. Six years ago, any estate over $100,000 should have been probated in court, unless it passed by a non-probate method such as joint tenancy or beneficiary designation. If there was no valid will, either his spouse, his children, or both would have been entitled to do the probate proceeding and/or to inherit property, and there should have been notice given to all the children if any court proceeding occurred. (Those notices would have at least the court address and case number which could be used to more quickly locate and view the court records.) Probate court documents are written with much legalese and form language which can be difficult to understand, so a consultation with an attorney is strongly recommended. If probate was never commenced and there is property such as real estate that you know your father owned, you can check with the county recorder's office to see if and when title was ever changed to someone else. I have seen many cases where no probate or title change was ever done, and had to be started even ten or more years after a death. If that is the case, you can start the probate proceedings yourself, but priority to be appointed administrator of the estate is given first to the spouse (not ex) and then to the children. Given the time that has passed and the added complexity this adds to an already complicated legal situation, I would strongly recommend meeting with a probate attorney to go over the situation and review and documents you can gather. Can't find what you're looking for? Ask a Lawyer Get free answers from experienced attorneys. Ask now 24,130 answers this week 2,489 attorneys answering Ask a Lawyer Get answers from top-rated lawyers. • It's FREE • It's easy • It's anonymous 24,130 answers this week 2,489 attorneys answering Legal Dictionary Browse our legal dictionary
http://www.avvo.com/legal-answers/for-how-long-after-the-executor--or-appointed-admi-720775.html
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• 1-800-409-4502 Live Chat with a Gearhead • Free 2-Day Shipping On orders over $50* • 100% Guaranteed Returns Gear Review 3 5 ContourHD..its just ok Member since  Price is good but it comes with a 2Gig micro SD card which is only good for about 30 mins of video. The other issue I noticed when I got the camera was that the video is slow on the "hi" setting. The audio is normal but since the video is slow they are not synced and it looks like you are just going super slow. Even after upgrading to the 16gig card with a "10" rating its still slow however, on the "Lo" setting it works like a charm. Super clear video without any blurr, its easy to operate with gloves on, the laser beams are actually quite helpfull when making sure its aimed properly, and the rotating lens is a nice touch. If the video worked on the "hi" setting I'd have given it a 4 star rating and if it had better low-light video quality I'd have given it 5. Member since  Responded on The default settings are: HI: 1920 x 1080 @ 30 fps LO: 1280 x 960 @ 30 fp Hook your camera to a PC/Mac and adjust it accordingly. Btw, it sounds like you're viewing the raw video file and your computer can't handle it, that's why it's playing back so slow. You need to edit and export it using an app like iMovie (or something similar).
http://www.backcountry.com/bcs/review/ContourHDits-just-ok/200124972.html
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| about this site | who we are | site map | reading tips | teaching tips | student tips | build vocab | | teaching vocab | hot links | visit Thai school | Bangkok Post | student weekly | home July 10, 2007 How old is your mummy? Radiocarbon dating and the secrets it reveals A mummy, inside the sarcophagus, and trappings are displayed at the Rosicrucian Egyptian Museum in San Jose, California on August 2, 2005. Silicon Graphics and Stanford University used a high resolution state-of-the-art CT scan of this 2,000 year-old girl mummy to create 3-D models of the four- to six-year-old girl's tiny body that let scientists visualize her resin-filled body cavities, her cause of death, even her baby teeth. AP All of us are slightly radioactive. This is because substances in the air we breathe, the food we eat and the homes we live in contain unstable atoms. These unstable atoms fall apart or decay from time to time giving out potentially harmful radiation. There is nothing we can do about it. It's called background radiation. This is the story of how it can be used. Necessary background All living things, including us, contain carbon atoms. As long as we are alive we are constantly exchanging carbon atoms with our environment. We take in carbon atoms in our food and release them by exhaling carbon dioxide into the air. Some of these carbon atoms are radioactive (about one in every million million). The radioactive carbon is called carbon-14. Some of the carbon-14 atoms decay while they are inside us, but carbon-14 atoms in our food are continually replacing them. This means that as long as we keep eating, the amount of carbon-14 in our bodies remains roughly constant. Where does carbon-14 come from? Carbon-14 forms in the upper atmosphere from nitrogen by the action of cosmic rays, mainly from the Sun. The carbon-14 combines with oxygen to form carbon dioxide. This is then taken in by plants to make food, a process called photosynthesis. We eat the plants, or the animals that ate the plants, and that's how carbon-14 gets into us. When a plant dies, photosynthesis stops. When an animal dies, it stops eating. In both cases the exchange of carbon with the outside world stops. The carbon-14 already inside decays, but is no longer being replaced. This means that the longer something is dead, the less carbon-14 it contains. Every 'half-life' (5,730 years for carbon-14) the amount decreases by half as shown in the graph. Big breakthrough In 1947, US scientist Willard F Libby and his team used the amount of carbon-14 in ancient remains to determine their age. At first the technique was used on remains of a known age such as bread that had been buried in Pompeii during the eruption of Mount Vesuvius in AD79, to see if it gave accurate results. It did. They then carried out tests on older remains, such as wood from the funerary boat of Egyptian Pharaoh Sesostris III, wrappings from a mummy believed to be Cleopatra, and charcoal from a campfire at Stonehenge. Radiocarbon dating was a great success, and in 1960 Libby was awarded the Nobel Prize in Chemistry. The most famous radiocarbon dating of all was of the Turin Shroud, a religious relic believed to be the cloth that Jesus was wrapped in after he died. It has a ghostly outline of a man with injuries to the head, chest, wrists and ankles. Samples of the shroud, together with samples from other relics were given to three different laboratories, one in Arizona, one in Oxford and one in Zurich. Each lab was given four samples with numbers, but they didn't know which was from the Turin Shroud. In 1989, their findings were published in the journal Nature. All three labs confirmed the Turin Shroud as being 600-700 years old. It was not the cloth used to wrap Jesus - it was too new by about 1,300 years. When the same method was used on the famous Dead Sea scrolls, they were found to be over 2,000 years old. Carbon dating method and its limitations Cleaning the sample and then burning it to produce carbon dioxide is how most radiocarbon dating is done. The amount of radiation coming from the carbon dioxide is then measured with sensitive instruments to determine the amount of carbon-14 present. A new method that uses accelerated mass spectrometry (AMS) makes it possible to count individual atoms of carbon-14, which means that much smaller samples can be used. Radiocarbon dating cannot be used to date very recent materials, because not enough of the carbon-14 has decayed. In fact, radiocarbon dates are followed by the letter BP ('before present', meaning 1950). Objects about 50,000 years old or more contain so little carbon-14 that it is difficult to measure the radiation. In recent years, AMS has been used to date objects as old as 100,000 years but there is much debate about the accuracy of these dates. Radiocarbon dating has advanced hugely since Libby pioneered it. One of the biggest problems was the assumption that the amount of carbon-14 in the atmosphere has been roughly constant for the last 50,000 years. We now know it hasn't been, due to changes in solar activity, volcanic eruptions and nuclear weapons testing. However, through comparisons with tree rings (dendrochronology), ice cores and coral samples, corrections can be made so that 'radiocarbon dates' can be converted into 'calendar dates'. Next time; What exactly is bandwidth, and why is it so important? Read our other science series here. Back to our home page |© The Post Publishing Public Co., Ltd. All rights reserved 2007 Last modified: July 9, 2007
http://www.bangkokpost.com/education/site2007/scjl1007.htm
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1. NOOK Sample  Go Back You've Reached the End of Your Sample Milton: Paradise Lost Customers Who Bought This Also Bought 1. The Canterbury Tales 2. The Divine Comedy: The Inferno, Purgatorio, and Paradiso (Everyman's Library) 3. The Elements of Style 4. The Gift of Music: Great Composers and Their Influence
http://www.barnesandnoble.com/sample/read/9780075536680
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1. NOOK Sample  Go Back You're viewing the NOOK Book (eBook) edition. A preview of the Other Format edition is currently not available. You've Reached the End of Your Sample Who Fears Death Customers Who Bought This Also Bought 1. Shades of Milk and Honey 2. The Dervish House 3. Alif the Unseen 4. Zahrah the Windseeker
http://www.barnesandnoble.com/sample/read/9781441879905
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Neighbor's Dog How can I keep my neighbors dog out of my flowers. I can't even tend to them without moving dog pooo! It's disgusting. Do spray's really work? Do moth balls work? Asking the neighbors to discurage the dog hasn't worked. Do they make a spray for bad neighbors. Ha! Just kidding. Please help! Depressed Gardener Submitted by BHGPhotoContest Thanks for writing. I'm sorry to hear about your frustrating situation! There are a number of sprays available, but I've heard mixed reviews on how they work. Some gardeners love them; others felt they were a waste of money. So they may be worth a try if you keep that in mind. Is it possible to put up a small, decorative fence along the property line to discourage their dog from crossing over? That's often the easiest solution, especially if they don't have a large dog. Other than that, I'm afraid I don't have a good solution other than talking to your neighbors and convincing them that their dog should not be making deposits on your property. After all, dog poo can transmit diseases to humans --- so it is a bit of a health hazard, especially if you don't own a dog yourself. Senior Garden Editor, Better Homes and Gardens  Answered by BHGgardenEditors Community Answers (2) I have made pepper spray, with red peppere and water. I put my peppers in a food processer and add water to make a spray. You have to reapply about once a week but it works good. Submitted by georgehilburn
http://www.bhg.com/app/advice/print.jsp?questionId=5816020quest&catref=S2
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UV Filters The beauty of using lens filters is being one step closer to a final product before the image leaves the camera. These little modifiers allow photographers to capture a desired effect in the field, rather than sitting at a computer desk. Some, such as the coveted circular polarizer, employ corrections otherwise impossible to achieve in post processing. After posing for a few gigabits of formals in a hall, you can sense the wedding party’s palpable relief when, weather permitting, it’s time to take it outside. If you’re lucky enough to have nicely landscaped grounds, it’s a great opportunity to stop fighting with the tungsten light sources inside and take advantage of that flash-friendly sunlight. In the days of film the value of placing a UV filter in front of your lens was never questioned. In addition to dampening the image-robbing effects of atmospheric ultraviolet radiation, UV filters also served to protect the front element of your lens from dust and moisture. Not long ago, filters were part and parcel of any worthwhile camera system. If you wanted to warm up the palette of a dreary day, you used a filter. Ditto for converting daylight to tungsten light, tungsten to daylight, and daylight to (or from) fluorescent lights. With the exception of the filters used for black-and-white photography (see the article Black & White Landscape Photography) the numbers of filters used for capturing color landscapes are few, mostly due to the fact that, in digital imaging, many white balance and filter effects can be addressed in camera. Seascapes are about sky, water, the physical dynamics of the points at which they meet, reflections and mirror imaging and most of all, the unique qualities of moisture-filtered light that one can only find where sky meets water. As a working photographer, the center of the universe is your camera bag and its contents. Your cameras and lenses are the tools of your trade. As you may have noted, both are mentioned in plural because just as you wouldn’t jump out of an airplane without a backup parachute, you shouldn’t attempt to photograph an emotionally spiked, non-repeatable event armed with only one camera. While many "looks" can be achieved in post-production, certain aspects of the image are better controlled before the image is recorded. Optical filters modify the light before it enters the lens. The benefit of using optical filters instead of digital filters is that there is no added time in post production and less degradation of the image quality, especially in HDSLRs, which already have limited color space and a highly compressed image. Not all that long ago, if you mentioned photographic filters to the amateur photographer it was assumed you were talking about traditional glass filters, specifically the round type that screws into the front of the lens. Syndicate content
http://www.bhphotovideo.com/indepth/category/tags/uv-filters
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Figure 2. Influence of temperature (A) and pH (B) on the enzymatic activity of soluble and immobilized NOX forms. In the case of the temperature, activity assays were performed in 50 mM sodium phosphate at pH 7, FAD 150 μM and temperatures ranging 25-90°C. On the contrary, pH effect on activity was analyzed keeping constant the temperature at 65°C at different pH values, ranging between 5-9, in presence of FAD 150 μM. In both experiments, soluble (empty rhombus) and immobilized (on CNBr-agarose) NOX (full squares) preparations were analyzed. For both graphs, relative activity was calculated assigning 100% of activity to the highest measured activity at one particular temperature and pH. Download authors' original image
http://www.biomedcentral.com/1472-6750/11/101/figure/F2
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Welcome Guest Remember me [ ] [ ] [ ] Listeners: 2 (Peak: 38) Songs: 29344, Authors: 4715 by rebb by rebb BitJam 180 - Out Now! Search BitFellas Search BitJam: Search Modland: Coders Interview Please complete the following form on behalf of the BitFellas.org demoscene community and information portal. * Handle, ex-handle(s) Name, birthday, origin Group, ex-group(s) 1. What was your first group, your role in that group and what did that group produce? 2. What motivates you to spend time on the scene? 3. What is your favorite color? 4. On what platform(s) did you begin your computing journey, and when was this? 5. What platform(s) do you use now? 8. What is your favorite programming language, effect, tool, coder, platform, book? 9. Discuss: your first steps towards becoming a coder, who helped you, what problems did you run into, your first effect, the future of demo coding 10. Which project that you worked on was the most exciting and interesting for you? And why? 11. What is your favorite demo, intro, megademo, retrogame, slideshow, musicdisk, diskmag, wilddemo? 13. What percentage of modern demos are 3d flybys? 14. What percentage of older demos are the same effects recycled? 15. What platform(s) needs more demos? 17. How did the scene alter since you are taking an active part in it? Can you explain why? 18. What are your dreams/goals in life, did scene help you and have you achieved them yet? Insert ASCII of your nick, group, or similar here: wrap in [code] [/code] to get a proper font FOR THE ADMINS EYES ONLY (Won't be displayed anywhere) : Your email * denotes required field Render time: 0.5510 sec, 0.4574 of that for queries. DB queries: 30. Memory Usage: 982,888b
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BrainyQuote Logo When you campaign and have to participate in so many debates just to the win the nomination of your party, you've had a lot of practice. You get to figure out as you go from one debate to another where you made your mistakes. By the time you get to the big debate you're pretty polished. Arnold Schwarzenegger Share with your Friends Everyone likes a good quote - don't forget to share.
http://www.brainyquote.com/quotes/quotes/a/arnoldschw458037.html
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Global Economics Moldova: Hooked on Remittances As young wage-earners continue to emigrate, this former Soviet nation becomes the country most dependent on money sent from abroad Since independence from the Soviet Union in 1991, Moldova rarely gets mentioned without the accompanying phrases "failed state," "Europe's poorest country," or "the only post-Soviet nation with a Communist Party president." Now there's a fourth—"the world's most remittance-dependent economy." According to the World Bank's Migration and Remittances Factbook for 2008, 36.2 percent of Moldova's GDP in 2007 came from money sent home by emigrants. The country tops the rankings together with Tajikistan. Around 25 percent of the population has left to look for opportunity elsewhere, and many of those émigrés are young and educated, a vital segment of the work force. This dependence on remittances highlights the vulnerability of a Moldovan economy hobbled by domestic strife, poor management, and, most recently, clashes with the Kremlin. At a time when some of their neighbors are reveling in newfound prosperity, the Moldovans should be hunting for the defibrillator. Yet the Communist Party-led government's track record doesn't promise much hope of progress from President Vladimir Voronin and new Prime Minister Zinaida Greceanii, whose cabinet was approved 31 March. In truth, Moldova rarely gets mentioned at all—it has been called the country the West forgot—so a quick primer is helpful. Clamped between Romania and Ukraine, Moldova has a population of 4.3 million. Despite some western leanings, the government has tried to stay close to Russia and has neglected developing civil society by, for instance, allowing independent media. Moldova's economy remains agriculturally based, with a strong wine industry. The transition to a market economy started with independence, but a significant reform package didn't come until 1994 under Prime Minister Andrei Sangheli of the Agrarian Party. Large-scale privatization of industry and agricultural land was at its center. The transition has not gone well. Economic output plummeted 60 percent between 1991 and 1999. Today, Moldova's economy is arguably the weakest in Europe. Per-capita GDP is well under the Central European average, at just $2,200, and nearly 30 percent of Moldovans are impoverished, according to the CIA World Factbook. True, average annual GDP growth between 2004 and 2007 was a robust 6.3 percent, but only because the economy had bottomed out; it could only go up. To be sure, Moldova has faced daunting obstacles to modernization. The break and subsequent war with Transdniestria has been painful, as the region accounted for 45 percent of Moldova's industrial base. Transdniestria declared independence in 1990 fearing Moldova would one day reunify with Romania. Cozy with Russia, it's been a persistent annoyance ever since, though Voronin's 11 April meeting with Transdniestrian President Igor Smirnov, their first since 2001, signals progress. That struggle contributed to Moldova's early economic belly flop, but today the Communist leadership is the biggest impediment to progress, according to Vlad Spanu, executive director of the nonprofit Moldova Foundation in Washington, D.C. While not overhauling the reform package of the mid-1990s since coming to power in 2001, the regime has leashed its chief objective—privatization—keeping a grip on the remaining state-owned companies. Communist leaders have also dragged their feet on crucial problems such as corruption and the weak media. The same goes for labor market inflexibility; it remains nearly impossible to fire someone in Moldova. Such inflexibility, along with high levels of corruption and poor infrastructure, repels investors. FDI barely broke $200 million last year, compared with $6.4 billion in Romania, according to the Heritage Foundation's latest Index of Economic Freedom. Exacerbating Moldova's troubles was the 2006 Russian ban on its wine exports. Criticized as retribution for Moldova's nascent interest in European integration, the ban cost Moldova dearly. Wine exports accounted for around 25 percent of GDP, with 80 percent going to Russia, so the entire economy was undercut. Russia has since relented, but exports haven't rebounded to pre-2006 levels. Cleary, Moldova's economy is in a deep hole. Corruption, infrastructure, labor legislation, an over-dependence on agriculture and remittances—these are all problem areas. But the salient question isn't really where Moldovan leaders should focus their attention in this miasma of dysfunction—just focusing would be enough at this point—but whether they will, especially with elections approaching in 2009. Voronin has intimated a desire to work on the economy, while Prime Minister Greceanii, a former finance minister, has said bolstering ties with the European Union is priority No. 1. That is especially encouraging, as European integration has invigorated the new Central and Eastern European EU members through increased investment, trade, and aid. Many observers argue, however, that the current regime is too authoritarian to pursue the meaningful free market, democratic reforms necessary for a legitimate shot at EU accession, which, though Brussels has said it's willing to increase cooperation with Moldova, remains a distant prospect. These skeptics point to the government's inaction on corruption—Moldova ranks 111 of 179 countries on Transparency International's Corruption Perception Index 2007—and its renationalization of industry to support their argument. Spanu is one such skeptic. Moldova's only hope for modernization and one day joining the EU, he says, is shedding its Communist leadership. "In order for Moldova to move forward, they need to have a capitalist-minded government. You cannot become a part of Europe with Communist leadership," Spanu says, adding that the party is gradually losing ground. "Moldova needs to pursue this path—or else it will become Turkmenistan." That's one dubious distinction Moldova certainly doesn't want. Provided by Transitions Online—Intelligent Eastern Europe GM's New General (enter your email) (enter up to 5 email addresses, separated by commas) Max 250 characters blog comments powered by Disqus
http://www.businessweek.com/stories/2008-04-22/moldova-hooked-on-remittancesbusinessweek-business-news-stock-market-and-financial-advice
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Metabonomic Signature of Celiac Disease Kathleen La Point Kathleen LaPoint is a biomedical writer with a B.S. in Molecular Biology and an M.S. in Bacteriology from the University of Wisconsin - Madison.   By Kathleen La Point Published on 12/23/2008 The emerging field of metabonomics offers a new way to understand celiac disease. Celiac.com 12/23/2008 - Metabolites are small–molecule products of biochemical processes in the body’s cells. Analysis of these metabolites can detect changes in the body caused by chemical toxicity, disease, gene mutations, or diet. Bacteria in the gut also contribute to this “metabolic signature”, so it is also a way to understand changes in gut microbe populations. Because metabolites are excreted from the cells into blood and urine, collecting these samples can be easy, noninvasive, and inexpensive. Chemical techniques like nuclear magnetic resonance (NMR) spectroscopy are used to analyze the samples. The results of NMR spectroscopy are chemical patterns, showing the simultaneous alterations of many compounds. The measurement and analysis of multiple metabolite changes in response to genetic changes or environmental stimuli is known as metabonomics. Metabonomics has a number of potential applications. Ease of sample collection may enable researchers to develop a rapid screening tool for diseases like celiac disease. Using metabonomics, it is not necessary to know the specific metabolites that differ in people with a given disease (the disease biomarkers). Rather than looking for the presence or absence of a particular biomarker, the overall pattern of metabolite concentrations is compared to patterns of people known to have the disease (the metabolic signature of the disease) and patterns of people who do not have the disease. Large numbers of metabolites are analyzed simultaneously, instead of one by one, providing a snapshot into what is happening in the cells at a given time. In this first study to investigate the metabonomic signature of celiac disease, blood and urine samples of 34 people with celiac disease were analyzed at the time of diagnosis, which was based on antibody tests and confirmed with biopsies of the small intestine. These patterns were compared to the metabolite patterns of 34 people without celiac disease. Using blood samples, researchers were able to predict celiac disease up to 83% of the time. Analysis of urine samples gave accuracy of about 70%. These accuracy rates are lower than those achieved with antibody tests, but this is only the first small study and refining the techniques may significantly improve accuracy rates. In addition, analyzing the metabolic signature may lead to a greater understanding of celiac disease and the cause of its various symptoms. For example, results from this study included lower levels of some metabolites such as pyruvate (a product of glucose breakdown) coupled with elevated levels of other metabolites such as glucose and 3-hydroxybutyric acid (a by-product of fat breakdown) in people with celiac disease. These results suggest a possible explanation for chronic fatigue experienced by up to 87% of patients with celiac disease—a possible impairment in the body’s ability to use glucose for energy. As expected, evidence of altered gut bacteria was also found, as were an increase in metabolites that indicate an increased intestinal permeability (“leaky gut”). After 12 months of a strict gluten-free diet, these altered metabolite patterns reverted to normal. Metabonomics is an emerging field of study, which like genomics, holds great promise in the understanding, diagnosis, and treatment of diseases like celiac disease. Bertini I, et al. The metabonomic signature of celiac disease. Journal of Proteome Research. 2008 Dec 11 [Epub ahead of print]
http://www.celiac.com/articles/21717/1/MetabonomicSignatureofCeliacDisease/Page1.html/print
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Reply to a comment Reply to this comment action22 writes: in response to NoMoDoh: You sound like you might be one of the chosen 10, or one of those few principals endowed with a free doctorate. These people were working on them during work hours, on corporate computers, when we were paying them to do the business of the EVSC. That is a form of white collar theft. The "savings" Smith listed, especially the soft drink contract are a joke. A drink contract has been in place since 2003 or 2004, when McCandless did some underhanded maneuvers to allow ONE provider to change his bid, but didn't give others the same option. As I recall, the proceeds are to go to the sports programs/ECA, not the General Fund, and will not benefit ALL the students. As for the Master's Degrees, the wonderful EVSC attorney, Pat Shoulders, should be taken to task and replaced for dropping the ball again. This is not the first time he has permitted a superintendent to do things that were in violation of state law, or at best, under the table favoritism to his cronies. He should have created a contract that protected the investment of $420,000 of the school tax dollars. Teachers have a card they must insert in the copier so every page of the paper we hear is in such short supply can be accounted for. That has been in place for a couple years, so paper savings are nothing new. The school board lets the superintendent drag them around by a ring in their noses. They can't even ask intelligent questions about issues they are to approve in meetings. If they don't have time to read the contracts, grant applications, change orders and personnel issues, before the meetings, they should either table the issues until they do understand them, or resign. I am really tired of your diatribe and the inaccuracy and innuendo of what you throw out. 1. No, I was not a recipient of the degree. Just a thoughtful individual that realizes there is value to this. 2. Quit bringing up moves that were made eons ago. McCandless hasn't been here for what, seven years! Smith did not list the soft drink contract as one of the savings - although the newest contract is providing the EVSC with $465,000. 3. I already acknowledged that some type of agreement should have been made, in hindsight. There is no one at the EVSC that disagrees with this, at this point. 4. There is no card that teachers have to insert into copy machines. The EVSC can track usage in other ways. The paper savings and the cost of the copy machines is a NEW thing.
http://www.courierpress.com/comments/reply/?target=61:305816&comment=1122030
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Reply to a comment Reply to this comment Captain_Hindsight writes: in response to newspeak: Some things are self evident. I would suspect that these young men are 2nd-3rd generation youngsters raised without a father figure in the house. This is the great society, get used to it. The state is the parent so let the state be responsible. Of course the state is the 53% percent that pay tax. I have little doubt these young men come from the 47% that don't pay tax and don't have a stake in this city. When they get get old enough to vote they'll possess none of the attributes of a good citizen, they'll be regular democrats in fear of losing their ebt card. Do you have any proof/evidence to substantiate anything you just wrote?
http://www.courierpress.com/comments/reply/?target=61:344408&comment=1368357
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Tombstone, Wyatt Earp memories corralled Every so often, cable will run one of the two 1990s movies about the gunfight at the infamous O.K. Corral. "Tombstone" starring Kurt Russell was released in 1993. A year later, Kevin Costner gave us "Wyatt Earp." Why two such expensive flicks about the same subject came out within a few months is a mystery, but that doesn't diminish my enjoyment of the productions. One reason for my interest is that I've been to this corner of Southern Arizona. It was in 1997 when our youngest son, Evan, was 10. We went to some spring training games in the Phoenix area, and saw Barry Bonds of the San Francisco Giants crank one completely out of the park. I also took him to Nogales, Mexico, so he could see all the squalor (the bodies of rotting roosters were in piles on the dirt streets) and be thankful he was born in the United States. Our stop in Tombstone was the last of the day. The 30-second fight on the afternoon of Oct. 26, 1881, pitted Doc Holliday and the Earp brothers — Wyatt, Morgan and Virgil — against the outlaw faction of Ike and Billy Clanton, Tom and Frank McLaury and Billy Claiborne. No one was killed on the Earp side. Billy Clanton and both McLaurys perished. The shootout took place in a very small space not much bigger than a two-car garage. We watched a re-enactment, and I talked with an old-timer who filled me in on the gold and ore rush that populated this part of the United States after the Civil War. A mile or two outside town is Boot Hill. Evan was fascinated by the explanations on the markers that death came by "strychnine" and "ptomaine," neither of which he could even remotely pronounce. Then we came to the epitaph of Lester Moore. "Here Lies Lester Moore. Four Slugs From A .44. No Les, No More." Evan nodded. Strychnine and rotting roosters were too much. Lester, he understood. — Garret Mathews • Discuss • Print Comments » 12 gbell56 writes: Kazz writes: I'm Your Huckleberry davebo42#144474 writes: best western ever! no one did doc better! lenniebriscoe writes: you're no daisey........ Cletusridge writes: Tell them I'm coming and hell's coming with me! elroy writes: Russell version was better. IMHO icurbones writes: Garrett not only is Tombstone really cool the history of all the building is facinating. Also just south of Tombstone is the mining town of Bisbee. Now this is something to see. On 4th of July they have a soapbox derby and the youngsters work on their cars all year. And to see them coming down the hills and into the city is quite the site. I would recommend a stay at the Historic Copper Queen Hotel which has a veranda to sit and watch the sites. Bisbee reminds me a bit of downtown Newburgh with all the hilly and winding streets. And there are those who look like they are living in the old west with the way they dress just like Tombstone. Just a really neat place to visit. And you might as well go to Old Tucson while your in the area. Now this is a place where the kids would really like. The movies that have been made in that location are too numerous to mention. And you could always go to the Desert Museum it truly amazing. Then there is Kitt Peak Observatory, you have to make a reservation but it is worth it, the older kids would love that but dress warm and I mean hats and coats because it's cold up on the mountain. Tucson is just a stunning city that I think shows how the Southwest really looks like. The architecture of the homes and building is second to none. And the overpasses and retaining walls around the city are very elaborate with murals and southwest designs. There is even a pedestrain overpass that looks like a rattlesnake. The whole area around Tucson and the many places to visit would be a great place to take your family. The kids would love it. davebo42#144474 writes: 1ConcernedCitizen writes: Why Kate, you're not wearing a bustle. How lewd. davebo42#144474 writes: in response to 1ConcernedCitizen: Why Kate, you're not wearing a bustle. How lewd. i allways thought he said , RUDE lol! gbell56 writes: Well, are you gonna do something or just stand there and bleed? notfair writes:
http://www.courierpress.com/news/2011/mar/18/no-headline---18a03gmtsr/
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-11 votes Please get this info to Ron Paul's staff I consider illegal immigration, and legal immigration two of our most important topics. Dr. Ron Paul has the WORST grade of all the Presidential candidates for immigration.... according to NumbersUSA. This is a very good organization, and he should not overlook what they have asked of him. Not doing so could hurt his chances of winning the Presidency! Here are 2 pages to check: Would you please pass this info on to Ron Paul's people, so that he can get a better grade? Illegal Immigration is very important in this election. It is my number one reason for voting. If we fixed the illegal immigration problem, we would be fixing a multitude of problems here, including National Security, Jobs, and the Economy! Not to forget the safety of our Law Enforcement officers! In 2010, South Carolina paid out OVER $330,000,000.00 to illegal immigrants, in one form or another. That is just ONE YEAR!! Please do what you can to get this info to his staff as soon as possible! Comment viewing options A friend wrote this ahile back NumbersUSA grades based on a single issue in a bill in isolation regardless of what else is contained in the bill, regardless of the collateral effects or ancillary issues. Thus if there is a single issue in a bill they like, they rank a congressman positively for voting for it and negatively for voting against it regardless of how much other poison is included in that bill. No good can come from swallowing poison regardless of how many tasty treats come with the poison. Take for instance the e-verify system. Regardless of all the "good intentions" behind it, it is a huge expansion of government, government bureaucracy, more paperwork, more compliance procedures, government "oversight" and delay, more expenses for the free sector, more employer liability and exposure both from alleged technical violations of government paperwork compliance and from exposure to the employers from delays or errors induced by the government itself. It is a horrendous big government expansion. Yet NumberUSA gives a plus to congressmen who support this ridiculous Soviet style bureaucratic system and a minus to the freedom lovers who oppose it. How absurd! It is just another big government expansion and makes NumbersUSA just another pro-big government organization. NumbersUSA gets an "F-" grade for its ability to grade any bill on any issue, including the immigration issue. NumbersUSA has no principled philosophy. It is single issue based with ad-hoc evaluations of bills. NumbersUSA fails to look at the collateral issues, the unintended consequences of advocating for bigger government, more bureacracy, more micro-regulations, and it fails to comprehend the larger picture. NumberUSA takes positions willing to wholly advocate for the poisons of big government, economic deterioration, further destruction of capitalism, more bureaucracy, more regulation, so long as they can feel warm and fuzzy inside for their "good intentions" of doing something about illegal immigration - regardless of the disease spreading ancillary consequences resulting from the expansion of government power. NumbersUSA is like a child playing chess that cannot see beyond the current move. Such feeble-mindedness is doomed to be played for checkmate every time. This is why canvassing is important... Consider a few things here, the "immigration issue" is very easy to identify, but not financially nor pragmatically easy to solve. Would you, as a rational free thinking individual, solely rely on an arbitrary ranking to determine your candidate? What do you think the *cause* of the problem is? If you said because the US has entitlement programs and a labor market that XBox fattened kids wouldn't ever dare do, then you're right there. If the solutions don't align to the causes of the problem (eg a border fence), then *regardless* of an arbitrary rank, the position is invalid. . Do it yourself. You can call national campaign HQ yourself and share your concerns with them. The number is at the bottom of ronpaul2012.com Second, if you knew anything about Numbers USA, it was founded by ex Sierra club members and eugenicists whose primary interest is zero population growth not anti-illegal immigration, though they view illegal immigration as pro population growth and hence oppose it too. They are globalist eugenicists and very much a part of the NWO plan, but coming from the right using conservative memes (even though they are fundamentally leftists). I belive they ended up endorsing Romney in 2008, blowing any credibility they have as an anti-illegal immigration organization. NumbersUSA is Isolationist NumbersUSA looks like an anti-immigrant organization. Getting an F from them is an A in my book. Mandatory E-Verify? Sounds like government intrusion into business. Lower immigration levels? If the concern is that there are too many people in the U.S., why don't they look into lowering birth rates as well? But, of course, that's not the concern. The concern is that we don't want more of those kinds of people. Where someone is born says nothing about their character, moral or otherwise. So this is borderline offensive and contrary to individual liberty, and judging people on the content of their character, not where they were born. Limit "unfair worker competition"? This is a nice example of misusing language. If I am an employer, and can find a cheaper piece of robotics abroad than here, then I should be able to buy it at that lower price. Similarly for labour. If my labour costs can be cheaper by bringing in foreign workers over domestic ones, then why should the government step in and tell me how I ought to run my business? That's my property, my business, my expenses. If you want to only hire domestic workers and purchase only domestic products, that's your right. But don't push your preferences on me at the point of a gun. This organization is garbage. I looked at that for about five seconds, and then nearly stood out of my chair to applaud the fact that Ron Paul got an F from this anti-freedom, xenophobic, and ISOLATIONIST (now used properly) policy-pushing group. Oh, come on! This has GOT to be a troll thread! I don't think that it hurts I don't think that it hurts Ron Paul's chances for the presidency to follow his own policy on immigration. The establishment hasn't been effective at controlling illegal immigration. I don't hear any revolutionary ideas coming from their end. Ron Paul wants to end entitlements rather than adding more regulations and federally funded programs. He feels that the laws that are already in place are adequate. We just need to enforce them. This doesn't fit the mainstream view so it's no wonder that he scored low by their standards. Maybe throwing more money at it and giving up more of our liberty isn't going to work any better in the future than it has in the past. This is bogus and based on comments taken out of context such as the fake tea party TPN voter guide (says we can't keep people in...) Refer to his page on immigration on the campaign site. No work, welfare, benefits, anchor babies or amnesty for illegals in ADDITION to strong border patrols. Jane Aitken, 35-Year Veteran Teacher Ron Paul 2008 Consultant GOP Woman of the Year 2009 Founder USPEINetwork @ Yahoo (Nat'l Edu Activism Group) Board Coalition of NH Taxpayers If they are giving him a bad grade on immigration it is because they havn't listened to his plan. He is the only one who wants to stop the free ride these illegals are given. No more free ride, no more passengers. It's that easy. I hope the press doesn't get this. It'll be carried by every newswire, especially this. Never mind, the Romney family is prctically Mexican, and this, only because they "enjoyed" their practice of polygamy so much that they LEFT the United States. Now, has that for a family tree? alan laney
http://www.dailypaul.com/204743/please-get-this-info-to-ron-pauls-staff
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0 votes US Arms Transfer Agreements Largest in History (USA supplied 77.7% of entire Globe in 2011) General Trends in Arms Transfers Worldwide. NOTE: This has got to play a HUGE role in our aggressive/offensive foreign policy. What does America export? Weapons, Weapons, and more Weapons. Mind Numbing 90 page .pdf released by Congressional Research Service From Report: The value of all arms transfer agreements worldwide (to both developed and developing nations) in 2011 was $85.3 billion. This was an extraordinary increase in arms agreements values (91.7%) over the 2010 total of $44.5 billion. This total in 2011 is by far the highest worldwide arms agreements total since 2004 Russia ranked second with $4.8 billion in agreements (5.6% of these agreements globally), down significantly from $8.9 billion in 2010. The United States and Russia collectively made agreements in 2011 valued at over $71 billion, 83.3% of all international arms transfer agreements made by all suppliers Comment viewing options Now you have woken up to the fact that war mongering B######ds have control of your government, and aren't about to let Dr Paul's non-interventionist policy get in the way of their profits. There is no profit in peace. You got that right Jill How evil is it that the govt is using the war machine and the MIC to keep the US from falling further into a financial depression? In my view, A depression can't be avoided but if we would allow the TBTF to fail and if we allowed all the bad debt to liquidate from the system the depression would only last a year or two...but TPTB are going to keep kicking the can down the road by selling weapons all over the freaking planet and picking fights with anyone that does NOT have nuclear weapons. (along with running the printing presses 24/7 in their non-stop looting of the American Taxpayer) I get sick to my stomach when I think about how Bernanke and Gaither can LITTERALLY just use computer keystrokes to type billions of dollars into their bank accounts or the accounts of whoever they choose and then just make an accounting entry that off sets their theft by charging it to the National Debt for our children and the unborn to pay. Man that burns me up! The proverbial can they keep kicking down the road has been kicked so many times already that no matter how hard they kick it...pretty soon it's going to be all crumpled up and and feel like it has been filled with lead. Won't be long before the can will no longer move when kicked. Kicking it once that happens will do nothing but break toes.
http://www.dailypaul.com/251466/us-arms-transfer-agreements-largest-in-history-usa-supplied-777-of-entire-globe-in-2011
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Comment: I've said it once before, I will say it once again. (See in situ) "I disagree on removing them The reason is two-fold. First and foremost is the simple fact that not every person here will agree with each other on every single issue. Nor does every single person here agree with even Ron Paul himself on every single issue. These people, so long as they genuinely believe in the foundations of liberty and aren't here only to shill for the status quo (I'm sure there's plenty of them; how small they must be to spend their time actively trying to denigrate this movement), are free to speak and act their conscience on issues. That's a primary component of what we believe in, isn't it? If there's some freedom thinker who's here to learn and they don't believe in legalizing freedom weed or gay marriage or not backing Israel or what-have-you, that's their prerogative. This leads into the second reason. Instead of taking the easy way out and suggesting that these people leave or be forced to leave, do the hard thing and work to open their eyes. If we cannot convince those among us to get behind the few things they disagree with the majority here on, how in the hell are we to expect ourselves able to convince people who have no involvement what-so-ever? These people come here for a reason, and if that reason isn't to just piss in our cereal, I think we owe it to them and ourselves to teach them why something like legalizing marijuana is important to freedom." I'll append this a little now. If you find that there's too many people you disagree with or that the mental calisthenics of talking to these people become too difficult, there's always the option of taking a break from the community. It's a healthy way to... readjust your range of reaction to others here, letting you not be so disappointed with those you don't agree with while simultaneously garnering a new appreciation for all the good that you come here for. I should clarify that I posted this as a supplement to what you were saying Granger, in hopes that Invalid will read it. Please don't take it the wrong way.
http://www.dailypaul.com/comment/2928097
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Comment: Tom Woods 2016... (See in situ) Tom Woods 2016... **NOTE: I am fully aware of Tom's objections to running, claiming it would be a waste of people's money. But I disagree with his assessment. I can think of no other person more capable to continue Ron Paul's goal of spreading the message of liberty than Tom Woods. Sue me! :D Educating people about freedom is Tom Woods greatest passion and he obviously loves doing it. The biggest classroom he could ever hope for would be running for president. Just sayin'... Tom's second objection to running is that his opponents could lift a few quotes from his writings and it would be all over. Who cares? They did that with Ron and looked what resulted! The greatest awakening to the idea of less government and more freedom in modern history. And it appears to be going global! If all that was a "waste of money" then sign me up for some more. I'm ready to waste some federal reserve notes! :p Again ---> Tom Woods 2016! ~wobbles but doesn't fall down~
http://www.dailypaul.com/comment/2937213
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Comment: I agree, (See in situ) I agree, that the American government has been usurped, and that happened with the FED which is an extension of the Bank of England. Everyone senses that the world is being taken over. The ones that are doing it are the world central bankers and the Rothschild family is behind all of it along with all their super rich friends.
http://www.dailypaul.com/comment/844465
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Every single moment of every Virginia football game, Perry Jones is right in the middle of something – a running play, a kickoff return, a sideline meeting with a coach, a tete-a-tete with a teammate. Considering where Jones was just 2 1/2 years ago, when he was arguably the best high school football player in Hampton Roads and, yet, didn't have a single scholarship offer from a Football Bowl Subdivision school, his level of involvement in the FBS game now qualifies as astounding. Jones, who is generously listed as a 5-foot-8 and 185-pound sophomore, is U.Va.'s starting tailback, one of two starting kickoff returners and the backup punt returner. He enters today's game against Virginia Military Institute (1-1) fourth in the Atlantic Coast Conference in all-purpose yards per game (121) and seventh in rushing yards per game (75) while splitting most of the carries with teammate Keith Payne, who is fourth in the ACC in rushing yards per game (85.5). "It's been going good," said Jones regarding the backfield duo he forms with the 6-3, 255-pound Payne. "We both have each other. When the defense is on the field, we come back and talk to each other, correct each others' mistakes and (talk about) something we could've done better, so it's working out for the best." If there's a painstaking quality to Jones' game-day approach – meeting with Payne to correct inconsistencies, hovering next to running backs coach Mike Faragalli to stay abreast of the backfield rotation, getting in offensive line coach Ron Mattes' airspace to pick up on assignment adjustments – perhaps it's because Jones is making the most of an opportunity that didn't come easy. Despite logging a school-record 141 tackles to go along with 11 sacks and four interceptions as a junior linebacker at Group AAA power Oscar Smith High in Chesapeake, and running for 1,831 yards and 30 touchdowns as a senior, Jones didn't attract much attention from recruiters due to his lack of size. In the long run, he chose a scholarship offer from U.Va., turning down his only other FBS offer from Boston College and an appointment from Navy. After Jones played in 11 games as a true freshman, but received just nine carries, the atmosphere changed when Mike London took over after the firing of former coach Al Groh. Players that might've had a difficult road to being legitimately considered for certain roles by the previous coaching regime suddenly had opportunities. View/Submit Comments for this story "The size is irrelevant," said Faragalli regarding Jones' stature. "The bottom line is Perry Jones is a football player. He's physical…He's one of the strongest guys on the team. He always gives his best. You can count on him in any situation - run, pass, it's irrelevant. Off the field, you can count on him doing the exact right thing and being a leader…He's as good as I've been around." In the spring, Jones and Payne, who returned to the program after sitting out all of last season, found themselves in the midst of a logjam for the starting tailback job. Jones came out of the spring No. 1 on the depth chart, and he hasn't given it up. London mentioned this week how U.Va.'s running game has transformed from a position that wasn't expected to be a strength into one of the most productive units on the team. U.Va. (1-1) is sixth in the ACC in rushing yards per game (178) at this early stage after finishing 11th last season (99 yards per game). Jones and Payne provide contrasting styles with Jones' slash-and-dash ability and Payne's bruising style. "It all depends on what the coaches want," Jones said. "Sometimes they have a set rotation for us. That's mainly early in the game, but after a certain point we put whoever in the game (London) feels is good for that certain situation." Jones, Payne and Raynard Horne, who Faragalli said he hopes to incorporate more into the running game in the near-future, have given U.Va.'s coaches some play-calling flexibility. U.Va.'s offensive coaches couldn't have asked for much more from Jones and his backfield mates entering the season. "I'm very comfortable with it," said Faragalli of the running back rotation. "We've got basically three guys playing the running back position. Any one of those guys can play in any particular situation. It started out where Perry was starting the game and playing a couple of series. Then, Ray Horne would go in for him. Then, Keith would go in on short-yardage situations and certain formations. It's still where we're going, but it's kind of taken on its own personality a little bit and it's going OK."
http://www.dailypress.com/sports/dp-spt-perry-jones,0,7893137.story
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"My first-ever game at home, they always have the Game Day Magazine sitting in the lockers. I was looking through the magazine and as all players do, I "My first-ever game at home, they always have the Game Day Magazine sitting in the lockers. I was looking through the magazine and as all players do, I came across the cheerleaders section. I instantly saw her and she was beautiful." - Elam, on discovering his future wife, Tamy, a former Broncos cheerleader (Post / Glenn Asakawa) Editor's note: Throughout this season, Broncos reporter Mike Klis and photographer Glenn Asakawa will help readers get to know one of the team's players on a deeper level. Asakawa's photographs will complement a weekly conversation with Klis about life, about work and about play. This week features kicker Jason Elam, whose 14 seasons make him the Broncos' longest-tenured player. Born in Florida, raised in Georgia, Elam graduated from the University of Hawaii before the Broncos made him their third-round pick in the 1993 draft. He and his wife, Tamy, have four children - Jason Jr., 8; daughter Jordan, 7; Julianna, 4; and Joshua, 2. Klis: There is no better gossip-page fodder than a Broncos player hooking up with a Broncos cheerleader. We know you first laid eyes on Tamy in the Game Day Magazine prior to the 1993 home opener. But I understand it would be an understatement to say she was hard to get. Elam: I ended up calling her, and she had a boyfriend. So I let it go. And two years later, we played San Francisco in the Japan Bowl in Tokyo. And I saw her again and I thought we had a little connection going, so I sent some flowers up to her room from a Japanese florist who didn't speak a lick of English. I wrote this little note to her. She had to read it on the bus over the PA. And they were making fun of her. And so during the game I'm trying to get her attention. I think it was Mike's first game as head coach. Klis: Wait a minute. Shanahan's first game as head coach and his kicker's got his head over with the cheerleaders? Elam: I couldn't get her attention. But then after the game, they're all huddled at the gate and I walked up in the middle of all of them, knowing it was going to be embarrassing, but I do it anyway. I ask her if she got all the flowers and all her friends were listening, giggling. Anyway, Tamy and her boyfriend were about at the point where they were going to call it off, so finally my timing was good. Save this Denver Post portrait to your monitor screen. Click the image above. Right-click your mouse over the new, larger image. Select "Set as Background." Voila! We ended up getting engaged about five months later and married during the offseason. Klis: As stories go, that's a keeper. Tell me about flying airplanes. Elam: When I was born in Florida, we lived right at A1 Air Force Base, so a lot of my parents' friends were in the Air Force, they flew a lot. So I remembered having boosters and stuff all over my room, airplanes. Klis: A typical boy who loved airplanes. The dream usually dies there, though. Elam: I graduated from college in December of '92 and I did a Pepsi commercial on the Islands. I got a little bit of money for it and the draft wasn't until April, so I wasn't doing anything other than working out and kicking. I had a couple buddies who were taking lessons at the local airport so I used my commercial money to take a few lessons. And I just loved it and kept getting my ratings. Klis: I read where you want to become a commercial pilot when you're done with football? Elam: When I first started playing with the Broncos I wanted to, but now it's just more of a hobby. I've got four kids and I don't want to be away from them. Klis: Christianity is at the center of your life. Elam: I grew up in a very Christian home in the Bible Belt. When I went off to college, I went to a melting pot of people, and I started questioning, "Why do I believe in what I believe?" Is it just because I'm from the South? I've got friends from India, I've got friends from Pakistan. Jason Elam wears his faith - Christianity - on his shirt. The "crosseyed" shirt references Hebrews 12:2, which encourages the faithful to keep their eyes Jason Elam wears his faith - Christianity - on his shirt. The "crosseyed" shirt references Hebrews 12:2, which encourages the faithful to keep their eyes on Jesus, who died on a cross. (Post / Glenn Asakawa) If I was born in a different place, I'd be a Hindu or a Buddhist or a Muslim. So I had to start from scratch, essentially, and it was quite a process. Klis: How did you ultimately resolve your inner conflicts? Elam: I don't think God wanted us to have blind faith. He gave us so much evidence, archeological evidence, historical evidence, that we can note almost with certainty. It takes way more faith to believe in evolution than it does Christianity. You've got this Goo Man they want you to think we came from. It doesn't make sense to me. Klis: Kicking might be the most specialized skill in football. Think about it: Everyone has thrown a football. Everyone has tried to catch a football. Everyone has tackled, blocked. But there's usually only one kid in town who can kick. Elam: I grew up playing soccer and I could always kick it a long, long way. I never knew where it was going. I remember I was in ninth grade and I went to a varsity football game for our high school. And our kicker was struggling and I remember thinking, "I can do that." So that next year I went out for the team. Klis: You mean you had never played football until your sophomore year in high school? Elam: Never. Didn't even know how to put my pads on. Klis: How long do you envision kicking, as long as you can make them? Elam: I'm looking (Monday) night at John Carney and he's 42 and Morten Anderson's 46. I'm 36, so I feel like I can at least play until I'm 40. Not having to worry about kickoffs is huge. And I feel like my swing is good. The Elam file * Kicker * 5-feet-11, 200 pounds * Drafted 70th overall out of Hawaii in 1993. * Holds Broncos records for career field goals (346), field-goal attempts (436), field-goal percentage (79.3) as well as extra points made (537) and attempted (540). * Enters 2006 ranked 10th in NFL history in career field goals.
http://www.denverpost.com/broncos/ci_4415454?source=pkg
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Sign in My Cart (0) All Categories View or edit your browsing history Products I Viewed Home > Shop Reviews > Cell Phones & PDAs > Cell Phone & PDA Accessories > GoerTek Cool Durable Fashionable Bluetooth Stereo Wireless Headset The Reasons Why a Bluetooth Headset is Important June 13, 2011 -- There are a number of reasons why a Bluetooth headset is important. One of these reasons is that this device allows you to multitask. Since you do not need to hold your phone when speaking, you can do other things as you talk. The other reason why a Bluetooth headset is important to have is that you can be able to use your cell phone as you drive. You do not have to get pulled over for using a cell phone while you drive because such a headset will allow you to drive safely. Wireless Stereo Bluetooth Headset Headphone A-19 With a wireless Bluetooth headset, your hands will always be on the steering wheel and your eyes will be the road. You will therefore drive safely by using this device. Using a Bluetooth headset is easy as long as it is compatible with your cell phone. You can connect it to your phone easily and start conversing right away. Since these devices are very affordable, you do not have to shy away from using this technology. These headsets are usually cheap because companies do not have to spend much to develop them. Another reason why a Bluetooth headset is important is that it is more comfortable to use it compared to holding the phone as you talk for more than a few minutes. As you may have experienced, talking on the phone for longer than thirty minutes makes the phone to become hot. This will not happen if you use a Bluetooth handset instead. The design of these headsets keeps on improving and for this reason, they continue enhancing the comfort of talking using a phone. Wireless Stereo Bluetooth Headset Headphone with Adapter SX-905 The other reason why a portable Bluetooth headset is important is that it prevents exposure to radiation. According to studies, cell phone use contributes to the exposure of the brain to radiation. These studies further state that this radiation can damage one's health and even lead to cancer but this has not been proven. The voices in cell phones are transmitted from an antenna found inside the phone as radio frequency radiation and this is what affects us. Some types of phones feature antennas that are close to the head and this causes people's heads to absorb radiation in higher quantities. You can prevent further exposure to radiation by buying a Bluetooth headset. The main reason why a Bluetooth headset is important is that it will enhance the quality of communication and life since it will provide you with comfort, style and freedom.
http://www.dinodirect.com/shopreviews/s-A0099000PM-42018/
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Cube (DVD) What would you do if you woke up in the Cube? - Cube (DVD) DVD Newest Review: ... mentions that they have about three days without food or water. Leaven replies "They've gotta feed us, right?" But do they? ... more What would you do if you woke up in the Cube? Cube (DVD) Member Name: bhayanid Cube (DVD) Date: 09/11/12 Advantages: Excellent Premise Disadvantages: None worth mentioning There are some movies that definitely live up to my expectations and some that don't. The Cube is one that exceeded my expectations. I had heard a few positives vibes and the plot line sounded intriguing, but I went in to the movie pretty open minded. 7 Strangers wake up in a mysterious cube with no recollection of how they found themselves there. Can they escape from this cube with seemingly endless rooms with it, especially when these rooms contain deadly traps, well only one way to find out.... Maurice Dean Wint - Quentin David Hewlett - Worth Nicole de Boer - Leaven Nicky Guadagni - Holloway Andrew Miller - Kazan Julian Richings - Alderson Wayne Robson - Rennes My Opinion Well this film has a massive cult following and it is pretty clear to see why. The budget for it was absolutely tiny, and I imagine the actors worked for pretty cheap, literally a few grand each and the rest was then spent on the gory effects, although to be fair there were only a few. This isn't a movie that is good due to any of the effects however, it is due to the tension and the story and wondering what you would do if you were in the same position. The cast is all pretty much unheard of, and since the movie has come out only one of them from my point of view has gone on to do anything decent and that is David Hewlett who became a major player in the stargate franchise and more specifically Stargate Atlantis. The acting is pretty decent considering how unknown they are. It is not perfect but they all portray themselves well and the main star for me was the character Quentin. I always love these types of characters and feel that he really carried the movie and added that extra element that lets say wouldn't exist otherwise. Thankfully the movie isn't just a straightforward slasher with each room containing deadly traps. Not all the rooms contain traps and it is interesting to see what the characters get up to in between and learn a little as the movie goes along about the actual Cube itself and why it exists and even why the characters were put in the cube in the first place. There have been a couple of sequels which I will hopefully review soon, but the originals are usually the best and this is no exception. Whilst not perfect it is still a very enjoyable film and has a lot of tension that is needed to really captivate the audience. Considering the budget and the lesser known cast I say this is well and truly mission accomplished. Summary: Add this to your watchlist
http://www.dooyoo.co.uk/movie-dvd/cube-dvd/1674934/
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Exposure triangle explanation please. Started 5 months ago | Questions thread Veteran MemberPosts: 4,470 Re: All fine and good, but ... In reply to texinwien, 5 months ago texinwien wrote: Jeff wrote: There certainly is an elegance to the Hv = Ev * t formulation, but I don't think we'll be seeing an iso-less world for a very long time. Physics is often quite elegant, and I think (and hope) you're wrong about ISO. First off, few shooters want to wait until PP to set image brightness. Most want an image now, out of the camera and straight to facebook. So somewhere the captured light has to be translated into an image. The camera might set the gain automatically assuming the user wants a 'middle grey', or the user might do it him or herself. But either way, there's a gain knob that has to be calibrated and set. Historically the gain knob is calibrated in ISO units. You prefer to do it PP, which is fine and actually quite logical, but you're still turning a knob, too. Call it whatever you like, it's just a proxy for ISO. Actually, I'd say ISO is a proxy for gain, and I think it's a confusing proxy for most beginners, and even for many advanced photographers (including a few professionals) who think that adjusting ISO has some effect on their camera's photosensitivity. The point is that we are moving from ISOful sensors to ISOless sensors. When all sensors are ISOless, I think we should start talking about the saturation sensitivity of a camera's sensor and the gain we wish to apply to a specific exposure. Just call it gain or brightening. Allow the user to set it before they record the photo (or have it set automatically by the camera) and allow the user to adjust it (in-camera) after the exposure has been recorded. The main point, for me, is that the topic of ISO always seems to be surrounded by a good deal of confusion, including this infernal exposure triangle. Get rid of it and replace it with an easier-to-understand and physically correct concept rather than the flawed conceit of ISO. See here for more discussion of the matter. There have been other discussions here about how to relabel and redesign the 'gain knob' on ISOless cameras. I think it'll happen, one of these days. There is confusion, no doubt.  But just replacing ISO with gain is rather minor tweak.  It'd be nice, sure.  But recasting it all in terms of what's happening at the sensor plane might not be the best way to resolve the confusion for most people. What I really care about are the image attributes, like image brightness relative to scene brightness, depth of field, motion blur, perspective, dynamic range, color. That we control them in terms ISO, sensor size, saturation, sensor efficiency, f-stop, focal length, etc., are all artifacts of the equipment and medium. If you're going to restructure the camera interface, why not do it terms of final image attributes.  Sort of a stripped down version of the Lightroom Develop panel where I can set brightness, shadows, highlights, color and tint, clarity, etc.  Now that would be truly useful, imho. Reply   Reply with quote   Complain Post (hide subjects)Posted by Keyboard shortcuts: Color scheme? Blue / Yellow
http://www.dpreview.com/forums/post/51783956
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VIOLENCE pays. The world's underground movements have proved that repeatedly in the past 50 years. Call them “liberation fighters”, as indeed they may be, or “terrorists”, as their enemies invariably do (and that too is often true), their methods often work. They are not to complain when governments respond with violence—and more of it. That is the short answer to the criticism already being heard of the sudden assault that ended Peru's four-month-old hostage affair (see article). President Alberto Fujimori did not rush in to violence. It was the Tupac Amaru guerrillas who did that—not for the first time—when they invaded the Japanese ambassador's residence in December. Thereafter, they behaved well; far better than most guerrillas (for notorious example, their local Shining Path rivals) would have. But they could not expect the government to yield to their demand that it free hundreds of their imprisoned comrades. Nor should it have: Peru is not a land under foreign occupation, and—whatever its or his faults, or those of its army or courts—it has a president recently re-elected. Still, the government was ready to talk. It talked, and talked, and talked. It was ready to allow the guerrillas safe passage to asylum in Cuba. It was they, not the government, who blocked that way out. So, in the end—but only then—Mr Fujimori ordered an armed assault. In it, all the hostage-takers were killed, including some ready to surrender. In a better world that would not have happened. But it did, and in the real one it is hypocrisy to shed many tears: the guerrillas took to the sword and they perished by it. The longer answer There is a longer answer, though. Peru's guerrillas, Tupac Amaru and Shining Path alike, are in part a hangover from a would-be far-left past, like the ones who have just made peace in Guatemala or those of El Salvador who have moved beyond peace into electoral politics. But none of these movements sprang into being just because men like Che Guevara—or, later, the Shining Path's Abimael Guzman, now in prison—ran around with Marxist or Maoist textbooks inventing them. They were formed—like Mexico's new-born Zapatists—in the real social conditions of the region, often in response to official violence directed at all who dared to challenge those conditions, however peaceably. Latin America's brasshats are back in barracks; entirely in some countries, not so entirely in others like Peru, Ecuador, even Chile. But social realities remain much as they were: poor Latin Americans now have the right to vote but still, too many of them, not the right to eat, let alone to decent housing, health care or schools. And the past ten years' swing to free-market economics, which promises to benefit both rich and poor, in the short term is widening the gap between them and indeed making some of the poor not just relatively but absolutely poorer than they were. That is today's challenge both for those now in elected power and (though it is less often remarked) for those who champion the poor: how to improve social conditions without reverting to the old ways of dealing with them. That is no new thought for the elected governments of the region, nor, even as they preach market forces, for institutions like the World Bank. If they ever expected free-market ideas to bring instant miracles, they know better now. What they do not know is the answer, how to handle the transition to a better life. Brazil's landless will not go away because some police force in the sticks shoots them down; but neither will they go because the national president is ready—as he is—to talk with them in person. Peru's justice system and prisons (and loose-cannon intelligence forces) could be brought into line, but its notably Amerindian poor would still remain a century behind the modern world, especially in their children's schooling. President Fujimori has met one challenge; huge ones still lie ahead, for him and his successors.
http://www.economist.com/node/86751?zid=305&ah=417bd5664dc76da5d98af4f7a640fd8a
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Plaid Cymru maintains opposition to Syria intervention Plaid Cymru maintains opposition to Syria intervention By staff writers 28 Aug 2013 Plaid Cymru's Parliamentary leader, Elfyn Llwyd MP, has welcomed Prime Minister David Cameron's decision to recall the Westminster Parliament on Thursday (29 August) to discuss and vote on the Syrian crisis. Mr Llwyd, whose party opposes military action, claiming that it would prolong the conflict and lead to further bloodshed, added that the motion tabled by the Government must offer clarity and lead to a vote on military action, not just a condemnation of the use of chemical weapons. Mr Llwyd explained:"While I welcome the Prime Minister's decision to recall Parliament to discuss the deepening crisis in Syria, I would add that a vote on the issue will be largely meaningless if it fails to directly address what military action, if any, is proposed. "A motion condemning the use of chemical weapons will not be enough. It must clearly outline the Government's definition of a 'proportionate response' so that the House can make an informed choice whether or not to support the Prime Minister's plans. "Plaid Cymru firmly believes that military action would prolong the conflict and lead to further bloodshed. "The fact that the intervention has received the backing of former Prime Minister Tony Blair - a man with so much blood on his hands - should set alarm bells ringing as far as the likely outcome of such action is concerned. "When the Government motion is published later today, it is crucial that it provides a clear and comprehensive definition of what form military action would take, alongside details of all diplomatic and humanitarian efforts being made to deescalate the situation. “The proposed language of the resolution put to the UN Security Council by the Prime Minister also gives cause for concern with “authorising necessary measures to protect civilians” offering little indication of his true intentions. “The last decade has seen the UK embroiled in bloody wars and paying a very high price for failing to prepare for peace. The same mistakes must not be made again.” Plaid Cymru (the Party of Wales), the Scottish National Party, and the Green Party of England and Wales are most likely to vote against military intervention in Syria tomorrow, along with rebels from the 'big three' parties - Labour (where backbenchers are most sceptical), Conservatives and Lib Dems. * 'Syria: what lies behind the clamour for military strikes?', by Simon Barrow: * More on Syria from Ekklesia:
http://www.ekklesia.co.uk/node/18930
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don't be afraid to dream big. Newer Older D R E A M. eh, this was an attempt. it was pretty hard to get a perfect shot since the wind was blowing every second. my thumb is kind of covering the E :c. sunsets are beautiful, no? :D. map.the.soul., k-w-e-e-n, amanda-liu, and 10 other people added this photo to their favorites. 1. map.the.soul. 35 months ago | reply dis is real naice. 2. breathe-serenity [deleted] 35 months ago | reply i really like this (: 3. mandalovv 35 months ago | reply the light is beautiful! great photo :) 4. absent-heart 35 months ago | reply haha thankyou! ^_^ 5. ☺susan☺ [deleted] 35 months ago | reply This is so great! Now do one that says NIGHTMARE ^_^ then you could put them together into a diptych. Just kidding. 6. e m ♥ i l y 35 months ago | reply love this!! :) awesome light 7. absent-heart 35 months ago | reply
http://www.flickr.com/photos/loveisinfinitex3/5442086373/
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Tested and Perfected by Food and Wine Ginger, Green Apple, Sweet Onion and Coconut Salad © John Kernick Ginger, Green Apple, Sweet Onion and Coconut Salad 1. 2 Granny Smith apples (about 1 pound)—quartered lengthwise, cored and thinly sliced crosswise 2. 1 small sweet onion, such as Vidalia, quartered lengthwise and thinly sliced crosswise 3. One 3-inch piece of ginger, peeled and cut into 1/8-by-2-inch matchsticks 4. 1/2 cup finely grated peeled fresh coconut 5. 3 tablespoons fresh lemon juice 6. 2 tablespoons finely shredded basil 7. Salt and freshly ground pepper 8. Lemon Verbena Oil 1. Toss the apples with the onion, ginger, coconut, lemon juice and basil. Season with salt and pepper. Add 3 tablespoons of Lemon Verbena Oil and toss; serve. Notes To grate your own coconut, start by preheating the oven to 350°. Twist a screwdriver into 2 of the eyes (small indentations) at one end of the coconut, and drain the liquid inside. Bake the coconut for 20 minutes to help the flesh pull away from the sides. Wrap the coconut in a towel, place it on a hard surface and crack it open with a hammer. Pull apart the pieces, and use the screwdriver to snap the white flesh away from the shell. Peel off the skin with a vegetable peeler, then grate the flesh on a box grater. Suggested Pairing The tart and sweet flavors of this salad find a good match in a bright German Riesling that echoes the apple and lemon.
http://www.foodandwine.com/recipes/ginger-green-apple-sweet-onion-and-coconut-salad/print
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Top Colours Quotes Ruggiero Ricci U2 is an original species... there are colours and feelings and emotional terrain that we occupy that is ours and ours alone. Gilbert K. Chesterton The idea is if you use those two shapes and try to colour the plane with them so the colours match, then the only way that you can do this is to produce a pattern which never repeats itself. Roger Penrose Silvia Cartwright All Colours Quotes
http://www.goodquotes.com/quotes/tag/colours
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Reply to a comment Reply to this comment foshizzle (Inactive) writes: "That side wants the federal government to prevent the federal government from forcing all states to recognize gay marriage." Not especially. The main reason the DOMA became necessary is because activist judges and legislators continue to ignore DOMA passed by individual states. The problem is if the law is struck down "on conservative grounds" like someone suggested earlier, then the provision that states aren't required to recognize the same-sex marriages from other states likely goes away as well. Sign up for email updates
http://www.gosanangelo.com/comments/reply/?target=61:148115&comment=338912
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Balanced Vs. Unbalanced I/O - How It Works by on ‎04-19-2010 01:42 PM - last edited on ‎01-17-2013 04:25 PM by Community Manager Learn the Basics of this Important Audio Concept By Craig Anderton In today’s studio, you’re likely to find some gear that has balanced analog inputs and outputs, some with unbalanced inputs and outputs, and some with both. Knowing how to interface them properly can make the difference between a quiet, well-behaved signal path, or one rife with signal loss, mismatches, and general unpleasantness. We’ll give a little theory about the two different types, then some practical interfacing examples. The typical musical instrument cable is an example of an unbalanced line that has two conductors. One wire is the ground line, which is also referred to as common, earth, shield, or DC return. The other is the signal line, often referred to as the "hot" line. The hot line carries the signal, and the ground acts as a voltage reference (Fig, 1). Unbalanced systems typically use two-wire, 1/4" phone connectors, or RCA jacks and plugs (as used in hi-fi gear). Fig. 1: The inner, “hot” conductor is surrounded by a grounded shield that fences out hum and interference (although shielding is not 100% effective). Almost all guitar processors and amps use an unbalanced input to be compatible with conventional guitars; computer audio interfaces often include an unbalanced, guitar-compatible input (Fig. 2) so you can plug your guitar directly into the interface without needing any other preamps or level-matching boxes. Phone Jack Fig. 2: The Mackie Onyx 400F is just one of many computer audio interfaces with a 1/4" input that can be optimized for guitar. A balanced system adds another signal line (called the "cold" line) to the "hot" signal-line-plus-ground combination in an unbalanced system. The basic principle here is that the two signal leads carry signals that are identical, but 180 degrees out of phase (Fig. 3). Thus, as a signal increases in voltage along one line, its mirror image on the other line decreases. Fig. 3: A balanced line system adds a "cold" line to the "hot" line of unbalanced systems. This type of signal has to feed a special type of input, found in transformers and certain types of amplifier designs, called a differential or balanced input that responds to the difference between these out-of-phase signals. The differential input is a somewhat unusual beast that rejects in-phase signals that flow into the line, such as hum and noise. This is because the kinds of noise and garbage that get into a balanced line generally spill over both signal lines equally. As the differential input responds only to the differences between the two signal lines, when the same signal is present on both lines, then there isn't any difference, they cancel out, and the differential input ignores them. The simplest way to explain the concept of a differential input is by analogy (Fig. 4). The balanced signals arriving from the previous stage feed the input, and are “differenced” to produce a final, unbalanced output inside your gear. That's all fine, but the real strength of this approach is that signals that are in phase cancel each other out. Some differential amplifiers can reduce these interfering signals (technically called common-mode signals) by over 90 dB—enough to make the interference fade way into the background. Fig. 4: Conceptual equivalent of a differential amp. Balanced lines, which involve more expense than unbalanced lines, are favored for long cable runs involving low-level signals, such as those generated by microphones. Unbalanced lines are usually satisfactory for situations where you have fairly high level signals running a short distance, as is often the case in project studios. 3-pin connectors (also called XLR connectors) are wired so that pin 1 is ground, pin 2 is the “hot” signal, and pin 3 is neutral. Some people will try to tell you that pin 3 is hot; don’t believe them. There is an international standard that specifies pin 2 as hot. Unfortunately, some manufacturers still wire their gear so that pin 3 is hot. There are two ways around this: go inside the unit itself and switch the pin 2 and pin 3 wires, or wire up a special cable that cross-connects these two leads (Fig. 5). Fig. 5: Adapter cable for converting pin 2 hot to pin 3 hot. Stereo 1/4” phone connectors are also used for balanced line connections as well. In this case, the tip is the hot lead, the ring the neutral lead, and the sleeve is ground. These are often referred to as TRS, for tip-ring-sleeve, balanced connectors. Although transformers were used for years to provide balanced inputs and outputs, they are not perfect devices. They can pick up hum and introduce a small amount of distortion and coloration; besides, they’re expensive. These days, it’s more likely that active circuits provide the ins and outs because they cost less and are generally conceded to add less coloration. These often use TRS jacks, which when matched with a properly designed input stage offer the advantage of working as either balanced or unbalanced inputs. If you plug in a stereo cable wired for balanced operation, then the hot goes to the tip, the neutral goes to the ring, and the ground goes to the sleeve. If you plug in a mono cable, the hot goes to the tip, but the ring shorts to the sleeve, as does the ground. The way most inputs are designed, when run in unbalanced mode the input stage has a gain of 6 dB but also includes a 6 dB pad. So the net signal level is the same, although the extra gain can add a tiny bit more noise. The same principle applies to feeding an XLR balanced input from an unbalanced output. To convert from one to the other, you feed the hot signal out to XLR pin 2. The ground connects to pins 1 and 3 (Fig. 6). Fig. 6: Driving a balanced input from an unbalanced output. I’ve made up several cables like this to make it easy to go from unbalanced outs (for example, from guitar effects) to balanced inputs, such as spiffy signal processors or hard disk recording interfaces. Feeding a balanced output to an unbalanced input generally, but not always, works the same way: XLR pin 2 provides the unbalanced hot line, while XLR pins 1 and 3 are tied together and go to ground. However, there is one caveat. With poorly-designed balanced outputs, tying the neutral output to ground could short the preceeding output stage to ground in such a way as to unbalance the output or worse yet, cause physical damage. This is seldom an issue, but if you’re paranoid or use a lot of older solid state gear with non-transformer-based outputs, consider wiring up a cable as follows (Fig. 7). Here, we’ve added a couple of 100 ohm resistors in series with pin 2 and pin 3. The one in series with pin 3 prevents a direct short circuit to ground. If it gets warm after a few seconds to a minute of operation, then simply omit it and leave pin 3 unconnected. You’ll still be able to get an unbalanced output if you just connect to XLR pins 1 (ground) and 2 (hot). Fig. 7: Balanced output to unbalanced input for the faint of heart. As you can see this isn’t really all that difficult. Interconnect your gear in the right way, and you need have no fear about mixing and matching balanced and unbalanced devices. Mic connectors are almost always balanced, as evidenced by an XLR jack--a common giveaway that the circuitry is balanced (Fig. 8). XLR Jack Fig. 8: A typical XLR input, as found in the mic preamp section of DigiTech's GNX4. However, as mentioned above, 1/4" TRS phone jacks can also be balanced, even though they appear to use standard 1/4" guitar cord-type jacks. But what if you run 1/4" unbalanced lines, but your gear has 1/4" balanced connectors? No worries. TRS jacks are electronically balanced, so if you plug in a mono plug, they simply turn into an unbalanced output. (The one place where you don't want to plug a mono plug into a stereo connection is the headphone out.) "Combination" jacks are a welcome addition to the connector scene. These combine an XLR connector and 1/4" TRS connector; the 1/4" connector is located inside the XLR section. This is a truly universal solution, as you can interface XLR balanced, 1/4" balanced, and 1/4" unbalanced lines with one connector. GO46 Combi Jack Fig. 9: Yamaha's GO46 mobile interface has combination front panel input jacks. Note how the pins from an XLR connector can fit in the three small holes bordering the internal, larger hole, which accommodates a 1/4" plug. In a small studio or onstage setup with relatively short cable runs, unbalanced connections work just fine — although you'll still probably want to use balanced connections for your mics. Most of the time there's no real need to rip your setup apart and rewire it with balanced connections. Where balanced lines shine is in situations with long cable runs, especially ones carrying low signal levels that are subject to noise or interference. The bottom line is that both technologies have their uses. But balanced lines tend to be more expensive, so if you don't really need to go balanced, you're probably okay sticking with unbalanced lines. Some gear you already have might work well in a pinch for signal translation. For example, I have an old (okay, ancient, but you get the point) TASCAM DA-30 DAT with both balanced and unbalanced inputs and outputs, as well as both AES/EBU and S/PDIF digital ins and outs. Although I don’t use it any more for recording, it makes a great translator: I can plug in a balanced signal and get unbalanced out, or vice versa, as well as convert AES/EBU in to S/PDIF out or the reverse. It can also serve as an A/D converter for turning an analog signal into a digital one, or a digital input into an analog output. Check out those connectors on your gear; you just might have some “free” translation capabilities lurking around your studio.
http://www.harmonycentral.com/t5/Lessons-Theory/Balanced-Vs-Unbalanced-I-O-How-It-Works/ba-p/34639794
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Thursday, October 10, 2013 Washing and Cooking: How the Rich Live in Honduras My friend, Calyspo, at Viva Veracruz, challenged a group of bloggers to publish photographs of our laundry and kitchen areas. It's part of his campaign to know each other better. Most bloggers in this circle are living in Mexico, and I am honored that they include a Louisiana girl in Honduras. Now, my washroom and kitchen are not typical of what my friends have in their homes. Most Hondurans do not have indoor plumbing. Most do not have stoves or washing machines. However, here are my accommodations, with a few explanations. The kitchen is where Madame Gumbeaux creates jambalaya, gumbo, and, occasionally,  Honduran specialities such as baleadas, arroz con pollo, etc. To the extreme left, not pictured, is a large pantry which serves as storage for food and other stuff. On the right, you can see I have bottled water, as the entire country is without adequate drinking water delivered via pipes.  Typically, laundry is installed outside, if one is lucky enough to have access to a washer and dryer. For your benefit, I labeled everything.  1. The pila, or washboard and water storage area, is where hand washing occurs.  2. The washing machine is used most of the time. I hand wash only occasionally. 3. The dryer is second-hand, and I use it sparingly. Most of the time, clothes are hung to dry.  4. The raft is my emergency hurricane device, in case I need to float to safety.  Marta or I usually hang all of the clothes to dry. Because the laundry area gets little sun, I toss the towels in the dryer in the late afternoon to complete drying and fluff them out. I do like fluffy towels. Other than that, I have no problem with clothes that are dried on the line. Marta is my friend, housekeeper, and sometimes ministry partner. She adores my dog, too.  BONUS: I added a picture of the small tank and pump that keeps water flowing in the house. The government provides water in this neighborhood via city pipes but not everyday. The pressure is not sufficient to supply the house with enough pressure to shower or wash. There is another tank to hold extra water that I fill up when the city releases water. I have to shut the water off in the house and use a series of levers to force the water to flow into the secondary tank. When I am not busy, I will show pictures of the barrels and earthen stoves that the poor use for cooking and laundry. Some of my friends have cooktops in the house, too, as well as refrigerators. Bathrooms for almost everyone I know are outside, either a hole in the ground leading to a pipe, or fitted with a toilet on top of the pipe. I wish I could add a picture of how bad those outhouses smell, but I think you can use your imagination. John Calypso said... Anita says if she saw your kitchen - she would not know what country you are in. Pretty standard and nice touches - upscale from our vantage point ;-) You were NOT supposed to clean the kitchen before taking a photo - cheating that! I did a surprise attack on Anita. Laurie Matherne said... I didn't clean up the laundry area as I was thinking of you. I am neat by nature. In fact, it pained me to post the laundry area with stuff showing on the shelves. My dad was super neat. My grandmother would probably be classified as OCD in today's world. Kim G said... That's a very nice kitchen, and by Honduran standards, must be nice enough for a TV cooking show. The raft gave me a chuckle, though. I hope you never need it. Frankly, I wouldn't want to be out in a hurricane on that raft, especially with Iggy trying to claw his way onto it with you. By the way, I added a link to your blog on mine. I don't know why I didn't think to do so sooner. Kim G Boston, MA Where our kitchen is feeling more and more gringo. Mrs4444 said... Beautiful home. Marta looks like a real sweetheart. The raft--awesome :) Andean said... Nice spacious kitchen. I also like that pump on the water bottle. I think a bogie board may be a better idea, only 'cause they don't deflate. LOL Laurie Matherne said... I like my simple bottled water pump, too. I am glad someone noticed the raft. Laurie Matherne said... I love my home and my friend. My raft? I think I would need a boat. Laurie Matherne said... Kim, thanks for the link. After experiencing Hurricane Katrina, I try to stay prepared for hurricanes. Thus, the raft. Seriously, I know people who survived only because of boats they had handy nearby. Felipe Zapata said... Electric stove?! That would send one's electric bill through the roof in Mexico. Why not gas? Not only cheaper but far easier to use, I think. That kitchen could be in Kansas. Laurie Matherne said... I prefer gas, too. However, I rent this house. Soon, I will be looking for something a bit more permanent. I hope. Kim G said... It's a good idea, but I think I'm with Andean in that you need something less fragile like a boogie board, surfboard, etc. If you truly had to use the raft during or after a hurricane, there'd be a TON of debris that would pop your raft in an instant. Also, I'm serious about Iggy. He'd definitely want to be with you, and he to would likely tear that raft to shreds in a moment. Laurie Matherne said... I apologize. The raft is a joke. I lived all of my life in hurricane prone areas. During hurricane season, I keep extra supplies on hand. I also keep the truck nearly full of fuel, because the flooding in this city is no joke. Of course, pets were neglected horribly during Hurricane Katrina. I would never do that. Kim G said... LOL...OK. I'm glad you're prepared, though. I lived in Houston for a few years, and was fortunate that no hurricane ever hit while I was there, though one came close. Fortunately it veered away.
http://www.honduras-gumbo.com/2013/10/washing-and-cooking-how-rich-live-in.html
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iOS app Android app More Stephenie Foster GET UPDATES FROM Stephenie Foster Talking With Kathryn Bolkovac About Her Experience as The Whistleblower Posted: 08/16/11 07:48 PM ET FOSTER: You were faced with a situation where the people you worked with were engaged in something very shocking. Do you have any insight as to how or why they got involved with trafficking? I really do not think there is clear cut answer for this. Everyone is an individual and is accountable to their individual behavior and potential illegal actions they committed and continue to commit in current missions. I think most people are truly just plain complicit in their thinking and tend to not get involved or look the other way to avoid any form of accountability, especially if they think that something does not directly affect them for their position. Then there is the group of people who can easily be swayed to join in on a pack mentality, who are morally and mentally weak or ignorant. When conditions are right as they have been and still are in many overseas missions around the world, or if they think they will not be caught or judged then it is easy for them to engage in illegal and corrupt behavior. They try to justify and minimize their actions. Finally, there are individuals who are just plain evil and corrupt, they see the money making potential of preying on the helpless and needy, and exploit every opportunity they can to make a buck, especially in an industry that involves sex. They are very good at dehumanizing, denial, and lying about what is going on. FOSTER: What do you think needs to be done to address the trafficking issue? What can government do? The trafficking issue at large is too complex to tackle with sweeping reform. There are so many different types of human trafficking each with different dynamics of funding the corruption. Obviously, many adults choose to be trafficked... or illegally transported across many borders to escape horrendous conditions in their own countries. These issues cannot be convoluted with organized criminal syndicates who are providing services to internationals all over the world, in the form of trafficking for forced prostitution. They are involved in the recruitment, abuse, desensitization, and sale of human flesh, into international missions as sex workers. This is what I want to discuss and what I think we can make a huge impact on based on my experiences as a former law enforcement officer, former UN employee, former representative of our U.S. government overseas, and as a former employee of one of the largest private government contractors in the world DynCorp. FOSTER: What can our government do? First, in the short term, the United States needs to take a serious look at why we are willing to allow private companies to engage in the profession of law enforcement. Government contractors are a needed and viable means to get many logistical and re-construction efforts accomplished. They are not a viable means for a protection force or as a mechanism for the use in training law enforcement officers in emerging democracies. Law enforcement is not a business. Policing is a calling. Does anyone really believe that private corporations are in this policing and operational mission business for anything but the money? We need to set an example with our own federal police selection units, perhaps via the Department of Justice as an example, why can we not recruit and most importantly train our own community police officers before we send them into these missions? My book accurately describes the pathetic training offered by the private company who sent me overseas, which I am sure was heavily subsidized with my tax dollars. It was a disgrace; none of us had even the minimum knowledge or idea of what we were supposed to be doing once we got into Bosnia. If we are to continue to send "rent a cops " overseas with inadequate knowledge and inadequate protections from corrupt private companies, some of whom had serious questionable policing backgrounds we might want to stop and think about how this damages our reputation and our goals. The private company who fired me had free reign to treat me however they saw fit, no one was in authority to stop them. They were exempt from all U.S. government accountability and have never been held accountable for what they did to me to this day. How has this changed? It has not. Second, get the Civilian Extraterritorial Jurisdiction Act (CEJA) out of committee and get it passed. It has been more than 12 years overdue. [NOTE: CEJA would allow the U.S. Justice Department to prosecute government contractors and employees for certain crimes committed overseas. It would complement the Military Extraterritorial Jurisdiction Act (MEJA), which provides similar criminal jurisdiction over Department of Defense employees and contractors but does not clearly apply to U.S. contractors working overseas for other federal agencies.] Third, make government contractors accountable for their employee actions, by putting a clause in their contracts that require them to facilitate and allow oversight of both external and internal investigations by outside government agencies, when probable cause exists that employees are suspected, or implicated in criminal offenses. They must cooperate in the facilitation of prosecutions. They can no longer just fire people, and hope the problem goes away, which automatically curtails any further investigation. Fourth, set examples by having the means available to prosecute and convict with meaningful sentences. FOSTER: What can individuals do? Learn, read, report, and stop burying your heads in the sand. Many of the people involved in these crimes could be your next door neighbor. Get local law enforcement initiatives started, and ask your police chiefs this question. What kind of training is being offered to your new recruits and officers on the streets to recognize and investigate all forms of human trafficking? Do you think a local police chief in the hills of Northern New Mexico, or in the farming community of southern Illinois, is even going to know what we are talking about? Does the local hotel have young female Hispanics working in the housekeeping department? They do not speak English, they have no documents, does he know what wage they are being paid and in what form? Think about it. I have been in these places have you? FOSTER: Many of the women and girls who are trafficked are promised jobs that don't materialize. What do you think would be effective to get the word out to them so that fewer of them fall prey to these types of promises? The only effect we can have on this is to stop the demand. FOSTER: How did you sustain yourself? Continued faith in our justice system, lots of hard workouts and sweat, many tears and my husband would make me a strong gin tonic with lots of lemon and ice once in a while. Follow Stephenie Foster on Twitter:
http://www.huffingtonpost.com/stephenie-foster/talking-with-kathryn-bolk_b_926772.html
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Spinach Dip Pita Recipes Enjoy our collection of spinach dip pita recipes submitted, reviewed and rated by ifood.tv community. Meet people who are looking for spinach dip pita recipes. CC: 2 Spinach Caramelized Onion And Yogurt Dip With Pita Crisps 1. Heat oven to 200C/fan 180C/gas 6. Heat 2 tbsp olive oil in a saute pan, then caramelise the onions and garlic with some salt and pepper for about 20 mins, until golden. Remove from the heat, scrape into a bowl, then let cool in the refrigerator. 2. Cut the... - 31.9672 Spinach Dip With Crisp Pita Chips In this video, Betty demonstrates how to make her wonderful Baked Artichoke-Spinach Dip with Pita Chips recipe. This is a favorite with just about everyone, and it is very easy to make! - 24.7667 You May Also Like! Spinach Dip MAKING 1) In a large pot heat water, cover and steam the spinach over high heat left clinging to its leaves for 3 to 5 minutes till wilted. 2) Drain and rinse in cold water and squeeze the excess water with hands. 3) Using a food processor puree spinach with... - 40.3454 Holiday Series: # 2 Spinach & Artichoke Dip Appetizer GETTING READY 1. Place the spinach in a medium size bowl and thaw thoroughly in the microwave using the defrost setting. 2. Place the spinach in a piece of cheese cloth or a clean kitchen towel and squeeze out all of the excess water. Set aside. 3. Thaw the... - 0 Spinach Hummus!!! Must See Hummus MAKING 1. In a blender, add all the ingredients, reserving some spinach for garnish. Blend until smooth. SERVING 2. Garnish the hummus with olive oil (optional) and spinach. Serve with pita bread. - 0 Spinach Artichoke Dip This popular Mexican variation of Spinach and Artichoke dip can make your traditional appetizers taste all the more delicious. As you make this fabulous delectable dish, feel yourself being in Mexico making one of the most popular dressing of the region. Chef... - 110.117 Spinach And Mint Hummus MAKING 1. In a blender, add all the ingredients reserving some spinach and mint leaves for garnish. Blend until smooth. SERVING 2. Garnish the hummus with olive oil (optional), spinach and mint. Serve with pita bread. - 0 Hot Spinach Artichoke Dip GETTING READY 1. Heat the oven to 350 degrees Farenheit. MAKING 2. Chop the spinach and the artichoke. 3. In a large mixing bowl, add the spinach, artichoke, garlic powder, minced fresh garlic,cayenne pepper,Asiago cheese and the Fontinella cheese. 4. Mix... - 93.0267 Spinach-onion Dip Spinach Onion Dip is indeed a healthy brew. This prepare-in-a-jiffy dish is rich with the flavor of frozen spinach, yogurt and onion. I prefer this spinach-onion dip less spicy, however you can increase the spice factor as per your taste by varying the... - 36.5817 The Home Grown Gourmet - Artichoke Dip A simple and delicious appetizer that is perfect for game day, your next party or just enjoyed as a starter course. This cheesy vegetarian delight is sure to be a crowd pleaser! - 99.4151 Queso Fundido A delicious cheese dip that can be served as a appetizer or just for a snack. This can be served with tortilla chips, pita bread, pita chips, or whatever sounds good to you. Super easy! - 110.236 Hummus With Cookin' Greens Rinse chickpeas (if canned) Combine chickpeas, spinach, tahina, olive oil, garlic and lemon juice in a food processor, sprinkle with salt and pepper, puree to consistency of choice. Taste, add more lemon juice or oil to personal preference. Serve with pita... - 28.8572
http://www.ifood.tv/network/spinach_dip_pita/recipes
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Cheddar Soup Recipe Difficulty LevelMediumHealth IndexJust Enjoy  Margarine1 Tablespoon  Onion1/4 Cup (16 tbs), diced  2 tablespoons each diced celery and carrot  All purpose flour2 Teaspoon  1 packet instant chicken broth and seasoning mix, dissolved in 3/4 cup hot water  Skim milk1 Cup (16 tbs)  Sharp cheddar cheese4 Ounce, shredded  Pepper1 Dash In small saucepan heat margarine until bubbly and hot; add vegetables and saute, stirring frequently, until tender. Sprinkle flour over vegetables and stir quickly to combine; gradually stir in dissolved broth mix and cook, stirring constantly, until mixture is smooth and thickened. Stir in milk and cook, stirring occasionally, until thoroughly heated (do not boil). Add cheese and cook over low heat, stirring constantly, until cheese is melted; season with pepper and serve immediately.
http://www.ifood.tv/recipe/cheddar-soup
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Cookie Ice Cream Supreme Recipe Difficulty LevelVery EasyHealth IndexAverage MethodMain Ingredient  Vanilla Ice Cream1/2 Gallon  Cookies package1 , crushed  1/2 cup raspberry preserves  Lemon juice1 Tablespoon  1 tablespoon orange-flavored liqueur 1. Place ice cream in large microwave-safe bowl. Microwave, uncovered, at 50% power 2 minutes or until softened, stirring once during heating. 2. Stir in cookies until well blended. Spoon into 10-inch pie plate. Cover; freeze 3 hours or until firm. 3. Just before serving, prepare sauce. In small microwave-safe bowl, stir together preserves, lemon juice and liqueur. Microwave, uncovered, on high 1 1/2 minutes or until preserves are melted, stirring once during heating. 4. To serve, let ice cream stand at room temperature 5 minutes; cut into wedges. Serve with warm sauce.
http://www.ifood.tv/recipe/cookie-ice-cream-supreme
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Skewers of Meat Sicilian Style Recipe Difficulty LevelEasyHealth IndexHealthy MethodMain Ingredient  Ground pork1 Pound  Finely chopped parsley1⁄4 Cup (4 tbs) (Fresh Ones)  Finely chopped fresh basil1 Tablespoon  Mozzarella cheese1 Pound, sliced  Crustless italian bread loaf1 , sliced  Eggs3 , well beaten in a flat bowl  Fine bread crumbs2 Cup (32 tbs)  Oil/Lard2 Cup (32 tbs) (For Deep Frying)  Salt To Taste  Pepper To Taste Salt and pepper the meat; add the parsley and basil. Mix well and form into 1 1/2-inch [4-cm.] round patties. Cut the cheese and the bread into round slices, or medallions, of the same size. On skewers, place in turn a medallion of bread and one of cheese, and a meat patty, repeating until each skewer is full, with bread at each end. Roll the skewers in the eggs, then in the bread crumbs, and deep fry in oil or lard. Slide the contents of the skewers off onto a large platter for serving.
http://www.ifood.tv/recipe/skewers-of-meat-sicilian-style
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Peter Clemenza Top Links main detailsbiographyby votesphoto galleryquotes by yearby typeby ratingsby votesby TV seriesby genreby keyword Did You Know? photo galleryquotes Quotes for Peter Clemenza (Character) from The Godfather (1972) The Godfather (1972) [last lines] Kay Adams: Is it true? Is it? Michael: No. [Kay smiles and walks into his arms] Clemenza: Don Corleone. Michael: Try and be patient. Michael: Be patient. Tessio: Mike, you're wrong. Clemenza: How long will that take? Michael: Six months. Don Corleone: Do you have faith in my judgement? Clemenza: Yes. Don Corleone: Do I have your loyalty? Clemenza: Yes, always Godfather. [Everyone except Hagen leaves] Tom Hagen: Mike, why am I out? Tom Hagen: Maybe I could help. Michael: You're out, Tom. Clemenza: The gun'll be there. Sonny: [to Michael, whose face is bruised] Michael, come here. Let me look at you. You're beautiful, beautiful, just beautiful. Hey, listen to this. The Turk, he wants to talk. You believe the nerve on this son of a bitch? He craps out last night and now he wants to have a meetin'. Tom Hagen: What did he say? Sonny: What did he say, badda-beep, badda-boop, badda-boop, badda-beep, he wants us to send Michael to hear the proposition and the promise is the deal is so good we can't refuse. Ha. Tom Hagen: What about Bruno Tattaglia? Sonny: Ah, that's part of the deal. Bruno cancels out what they did to my father. Tom Hagen: We ought to hear what they have to say, Sonny. Sonny: No, no, no, not this time, Consigliary. No more meetin's, no more discussions, no more Sollozzo tricks. You give them a message from I want Solozzo if not it's all out war we go to the mattresses. Tom Hagen: Some of the other families won't sit still for an all out war. Sonny: Then you tell them to hand over Sollozzo! Tom Hagen: Your father wouldn't want to hear this, Sonny. This is business not personal. Sonny: They shoot my father and it's business, my ass! Tom Hagen: Even shooting your father was business not personal, Sonny! Sonny: Well then, business is going to have to suffer. And please, do me a favor, Tom. No more advice on how to patch things up just help me win, please? Sonny: Alright, what about him. Tom Hagen: He's definitely on Sollozzo's payroll and for big money. Now, McClusky has agreed to be the Turk's bodyguard. Now what you have to understand, Sonny, is that while Sollozzo's being guarded like this he is invulnerable. Nobody has ever gunned down a New York police captain before. It would be disasterous. All the other five families would turn against you. The Corleone Family would be outcast. Even the old man's political protection would run for cover. So, do me a favor, take this into consideration. Sonny: Alright, we wait. Michael: You can't wait. Sonny: What? Michael: You can't wait. I don't care what Sollozzo says about a deal he's gonna kill Pop. He has to. It's a key for him. You gotta get Sollozzo. Clemenza: Mikey's right. Sonny: Alright, Professor, what about McClusky. What do we do with this cop here? Michael: They want to have a meeting with me, right? It will be me, McClusky and Sollozzo. Let's set the meeting. We get our informants to find out where it's going to be held. Now we insist that it be held in a public place, a bar or a restaurant where there'll be other people there so I'll feel safe. They're going to search me when I first meet them, right? So I can't have a weapon on me. But if Clemenza can figure a way to have a weapon planted for me, then I'll kill them both. Sonny: [laughing] What are you gonna do? Nice college boy, didn't want to get mixed up in the family business. Now you want to gun down a police captain. Why? Because he slapped you in the face a little? What do you think this like the Army where you can shoot 'em from a mile away? No you gotta get up like this and, badda-bing, you blow their brains all over your nice Ivy League suit. C'mere. [Kisses Michael on the head] Sonny: What the hell is this? [to Rocco who has killed Paulie in the car] Peter Clemenza: Leave the gun. Take the cannoli. Paulie Gatto: Yeah, I'll think about it. Sonny: How's Paulie? Clemenza: What's with all the new faces? Clemenza: ...Jesus Christ. [Clemenza prepares Michael for his meeting with Sollozzo] Clemenza: What's the matter, trigger too tight? [With a loud bang, Michael finally discharges the gun] Michael: Ow! My ears. Michael: Sit down and finish my dinner. Michael: How bad do you think it's gonna be? [Clemenza now finishes working on the gun] [Clemenza hands the gun back to Michael] [Michael gets ready to leave the house] Sonny: Where're you going? Michael: To the City. Michael: No, I'm just gonna go see Pop. Sonny: I don't care, send some bodyguards with him. Sonny: Yeah? Well take care, all right? Michael: Yes, sir. [Michael leaves] Sonny: Send someone with him anyway... [Paulie enters the Corleones' study] Sonny: What is it? Paulie Gatto: You want me to hang around? Sonny: Yeah, hang around. You all right? Paulie Gatto: [coughing] Yeah, yeah... Paulie Gatto: Nah, nah. [Paulie leaves] Clemenza: Understood. The Godfather: The Don's Edition (2007) (VG) [Sonny hits him on the back of the head] [he enters the hospital]
http://www.imdb.com/character/ch0000812/quotes
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Posters is extremely impressive and makes a famous wall decoration, the poster dimension isand the price is $0.00. If you're trying to ask for top recommendedPosters with low-priced price, this unit is the right deals for you. Price: $0.00 It is high qualityPosters design you will not find anywhere else. It is a very detailed, shimmering, good and affordable system to get things done. The product takes an entirely different purchase from most other getting-organized posters. This is a famous painting, you can see the details of the paint strokes and the color is several more realistic than in some of the prints. Large shiny poster is a marvelous addition for kid's room, college dorm or classroom. The product might be fantastic to have some examples of how visitors have applied the posters, along with the mechanics of how they make it work. This item is an fabulous poster for men who fan. This product works pleasant and it's fine much whatever is expected. This item itself would have been right, and this item is usable fot people.Posters has a superb size , shining color and exactly as the production description stated.
http://www.keyposters.com/posters/bridgeoverariverwashingtonmonumentwashingtondcdistrictofcolu1.html
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Reply to a comment Reply to this comment mamatomany writes: in response to Speaker_to_Animals: (This comment was removed by the site staff.) "Fireworks are no more a waste of money than planting petunias, watching TV, painting a mural, or any other 'useless' activity. It is all in the eye of the beholder." The difference between fireworks and these activities is that, last time I checked, none of those hobbies threaten the life, limbs and homes of those around you. When is the last time planting a flower or watching tv set your neighbors house on fire? When is the last time painting a mural resulted in second degree burns? Just because I think all personal fireworks should be illegal doesn't make me part of the "sniveling anti-fun crowd" makes me a person who would prefer to enjoy a large professional fireworks show without wondering if back at home, my neighbors carelessness has set my roof on fire.
http://www.kitsapsun.com/comments/reply/?target=61:241269&comment=237091
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Reply to a comment Reply to this comment SallySantana writes: I am hopeful that those that complain about the pay and benefits, golf games, vacations, etc. of our present president, also complained about every past president as they did the same. Re pay disparities... we can't pay the surgeon and medical team that saved us or our family member what they're worth - no one could afford it! Isn't saving a life more valuable than throwing a touchdown? Now THOSE guys are overpaid, in my estimation. But then, our priorities are in line with what we value most...
http://www.kitsapsun.com/comments/reply/?target=61:383210&comment=588583
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Reply to a comment Reply to this comment Engloid2 writes: in response to TSCinSFO: Been_there writes: E-verify wouldn't have made a difference. Yes it would have. I use E-Verify at my company and if EVERYTHING doesn't match it rejects it. If the SS# was fake or being used by another person, or several in most cases, it catches it. Only once, out of 1,000's, was one rejected that was legit, and it was straighten out within 48 hours because someone had stolen their identity and used their SS#. That illegal alien was picked up by ICE and deported when they showed back up for work from what ICE told the victim. People don't seem to understand that the same social security number is very often used by many illegal immigrants. Copies of the SS card and other info are copied and sold everywhere. It's like if you're a crackhead, you know where to get crack. If you're not, you don't. Likewise, if you're an illegal immigrant, you know where to get a fake identity.
http://www.knoxnews.com/comments/reply/?target=61:285449&comment=1794769
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Start your profile Close window Kurtis Mantronik Everyone’s tags More tags Kurtis el Khaleel (Arabic: خليل) (born September 4, 1965), known by the stage name Kurtis Mantronik, is an American hip-hop, electro funk, and dance music artist, DJ, remixer, and producer. Mantronik was the former leader, DJ, and keyboardist of the influential 1980s old school hip-hop and electro-funk group Mantronix. Currently, Mantronik lives in Britain, where he has produced and remixed house and techno music tracks by artists such as Kylie Minogue, Fatboy Slim, The Chemical Brothers, Victoria Beckham, Liberty X, and Mim. Top Albums Listening Trend 8,456listeners all time 35,165scrobbles all time Recent listeners trend: Create a profile Leave a comment. Log in to or sign up.
http://www.last.fm/music/Kurtis+Mantronik
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1. WHEN THE RAINS CAME: Hurricane Isaac rolls toward the GOP convention in Tampa, Fla., threatening a thicket of wet, windy disarray depending on how and where it hits. The storm is on course to pass west of the convention city. 2. WAIT 'TIL TUESDAY: Republicans announce a leaner convention schedule to begin Tuesday—after canceling all events Monday except for a symbolic, 10-minute opening because of the approaching storm. How will a town full of eager delegates spend the day now? 4. LOGISTICAL RESHUFFLINGS: Even with no formal convention events, lots of GOP luncheons and engagements are scheduled—and some are being relocated to accommodate possible inclement weather. Among the displaced happenings: a breakfast with New Jersey Gov. Chris Christie, and a brunch with former Secretary of State Condoleezza Rice and House Speaker John Boehner.
http://www.marinij.com/opinion/ci_21406651?source=pkg
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Mixed or average reviews - based on 20 Critics Critic score distribution: 1. Positive: 1 out of 20 2. Negative: 5 out of 20 1. 90 For the most part, though, Spyro is a graphics bonanza with blasts of color and eye-catching nuances, such as rippling water, glowing flames, and shimmering portals. 2. While there are a few tweaks, this is essentially the same game as the previous three. 3. Looks good and sounds great, but Enter the Dragonfly lacks depth of play. It is a safe arcade-adventure outing. 4. The graphics are nothing to be proud of, as they seem very similar to what we were presented with on the PS one not too long ago, and nothing in terms of the gameplay or style has changed a bit or improved upon in any way shape or form. 5. All in all, the game felt more like a task I had to complete rather than something to be enjoyed. 6. Simply a decent been-there-done-that platformer. [Jan 2003, p.40] 7. 60 Only a slightly better than average platformer. Slightly. Up against games such as "Sly Cooper" and "Ratchet and Clank," it doesn't hold a candle. 8. To get the most benefit from this game this should be your first Spyro game. To many diehard fans, it may be their last. 9. Gameplay just hasn't changed enough. You feel like you're playing a throwback, or a golden oldie, not a new release. 10. More of the same, but not quite as good, with crappy minigames and a framerate that's more offensive than calling your political foe a putzhead. [Jan 2003, p.132] 11. Run, not walk, far away from this piece of junk. Do not buy this game at all costs or you will regret it. You have been warned. 12. 55 An entirely average platform romp skewed for a dumbed-down audience that doesn't live up to expectations. 13. Little children or people with no desire to experience innovative gameplay take notice; Enter the Dragonfly has your number dialed. 14. There really isn’t anything that separates it from other Spyro games. Actually in a lot of ways the PS1 games are much more enjoyable and original. 15. The gameplay is not very addictive and feels more of a farce than an enjoyable adventure game. 16. Having been developed by Check Six Games this time around (since Spyro's original developers, Insomniac, left to pursue other interests), Spyro: Enter the Dragonfly, complete with N64 graphics, Carrot Top-caliber annoying sounds, and gameplay that's more bland than a sandwich without mayonnaise, is quite simply craptacular. 17. 42 Control-wise, I hate the slippery, jittery interaction between character and camera. [Jan 2003, p.52] 18. 40 Check Six Studios has clearly designed this installment of the Spyro franchise for very young gamers, and with that demographic, the title works well. Unfortunately, this limited scope will bore anyone familiar with other platforming titles. User Score Generally unfavorable reviews- based on 58 Ratings User score distribution: 1. Positive: 8 out of 41 2. Negative: 28 out of 41 1. Sep 22, 2012 After the success of the first 3 Spyro games on the PS1, Insomiac decides to randomly abandon the Spyro series. The series is then sold to Universal and the first game they decide to release is Enter the Dragonfly for the PS2 and the Gamecube which is the first time a Spyro game was released on a non Sony console. Some people say the reason why the game is bad has something to do with Universal rushing the game for the holiday season which caused a whole bunch of glitches and bugs to be left alone. I believe there is more to it than that. First off, the game is completely unoriginal. The story is copied from Spyro 1 but except for rescuing dragons, you are rescuing dragon FLIES. Yeah, that's totally 100% original. That's only the tip of the iceberg. Speaking of ice, Spyro can now breathe ice as well as water, lightning, and water including Spyro's trademark, fire. What? Dragons are known for breathing fire. Not ice, water, and lightning. And the worst part is that they don't do anything different except breathing water is completely useless. And do you want to know the worst part about this tragedy? THE GAME LOOKS JUST LIKE THE PS1 GAMES. The developers showed little to no effort trying to make the game look good, or play good for that matter. This game is bad. I do not understand why Spyro was not put out of his misery instead of keeping Spyro on life support. And sadly, this is not the worst game of the Spyro series. Full Review » 2. Oct 21, 2010 If you love the Spyro series and had great anticipation for the fourth instalment, then your will be extremely disappointed. For the first time our heroic little dragon comes to the PS2 and for a PS2 title we expect something massive, well that's what I think a next gen game should have if you want to improve it. Instead we get something that is unoriginal and could even have been done on the PS1 and without all its flaws. It starts off with Spyro and his friends celebrating the new arrival of dragonflies who will be each young dragon's new guardian. However Ripto (the main antagonist from Spyro 2 who somehow managed to survive the boiling lava, or that's the developers excuse for saving time by not creating a new villain) crashes the party and scatters all the dragonflies around the world. It's up to Spyro, his guardian dragonfly Sparx and friends to rescue the dragonflies and stop Ripto and his minions from foiling his plans. Gameplay is similar to the previous 3 games, Spyro can run around, charge, headbash, glide and breathe fire but there are some new moves. There are 4 new breath attacks, bubble, ice and bolt which you get when you find the sacred runes. Bubble breathe is used to catch the dragonflies but some are earned by completing tasks set by your friends. There are gems to collect once again which are scattered everywhere in each level and in chests or metal creates. That's pretty much it really, there is nothing in this game that is fresh or original and they got the same villain from the second Spyro game however that is only the minor issue. The real problem with this game is it suffers from too many flaws such as graphical glitches, inconsistent framerate, long loading times sound issues and sometimes freezes meaning you have no choice but to reset your console and start back from where you last saved your progress. According the sources this game was rushed in order to be released at Christmas time, if so then it is not all the developers fault but also the publishers. Had it not been for all the major issues I'd give this game a 6 or 7, however one bug is far too many. Quite simply this is not just the worst Spyro game but the worst game I have ever played in my years of gaming. Full Review » 3. RoboR. Oct 5, 2003 The spyro legacy is desecrated by this uninspired "trainwreck of a game". The developers responsible should be locked up and forced to play this glitchy, frustrating and half-baked tripe until their thumbs are bloody stumps and they have completely lost their sanity. Who cares about the fancy water ripples and flame effects when the frame rate is worse than ps1 versions and the game locks up each time you play it. Worst sequel ever. Full Review »
http://www.metacritic.com/game/playstation-2/spyro-enter-the-dragonfly/critic-reviews
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User Score Mixed or average reviews- based on 527 Ratings User score distribution: Review this movie 1. Your Score 0 out of 10 Rate this: • 10 • 9 • 8 • 7 • 6 • 5 • 4 • 3 • 2 • 1 • 0 • 0 1. Submit 2. Check Spelling 1. May 27, 2011 2. May 26, 2011 3. Jun 3, 2011 4. May 27, 2011 5. Jun 26, 2011 6. Jun 3, 2011 Wait for DVD 7. May 30, 2011 8. May 27, 2011 9. May 26, 2011 gain, but not anytime soon. 10. Sep 27, 2011 11. Jun 16, 2011 12. May 27, 2011 13. Jun 3, 2011 14. Jul 26, 2011 15. Jun 10, 2011 16. May 27, 2011 17. Jun 5, 2011 18. Jun 4, 2011 19. Mar 22, 2012 20. Jul 10, 2011 21. BKM Jan 14, 2012 22. May 28, 2011 23. May 31, 2011 24. Jun 5, 2011 25. dz9 Jul 27, 2011 26. Dec 28, 2011 27. Dec 26, 2011 28. Jan 31, 2012 29. Mar 11, 2012 30. May 28, 2011 31. May 31, 2011 THE MOVIE WAS GREAT i really like it, one of my friends asked me yesterday if they have to watch the first one before seeing tis one. i dont think its neccc , i mean the idea is the same , but i guess it has to be well its a sequal. i liked it and i laughed a lot which is what i paid for. 32. Jun 5, 2011 Absolutely horrendous. The only reason I didn't leave halfway through is because I was with two girls and didn't want to look like a dick, and didn't want to do the characters a disservice - because I truly loved the original. I came in with no expectations - the critics said it was bad but people I know seemed to love it. In fact, everyone in the cinema was roaring with laughter. I wasn't. 33. May 27, 2011 The Hangover, Part II is not what you expected to see, but not nearly as good as the first movie. I don't think that movie will not be the best sequel and even though the scenes are not that bad, the characters are that bad, the cinematography is not that bad, it's the story has the same plot as the first one. I just wonder that why are doing all over again and why do they do same issue all over again. The scenes could be funny sometime, but it's very vulgarly nasty and too tedious to see. Expand 34. Jun 29, 2011 This movie had it's funny moments, but all in all, this movie's main flaw was it's unoriginality. It was basically exactly like the first movie, just in a different city. 35. Jun 8, 2011 I found this movie of the same standard as the first movie. Both were exceptionally funny and showed plots which gave good entertainment to the audience 36. Jun 2, 2011 Very entertaining and hilarious...but very similar to the first movie. It was as if they made the script from the first movie into a Mad Lib, and just replaced a few words to write the script for Part II. All you have to do is replace tiger with monkey, missing tooth with tattoo, Vegas with Thailand, roof with....well, I don't want to give the whole thing away. I wish the script was more innovative and more of a twist on the original, rather than copying it, but it was still funny and entertaining nonetheless. I'm still glad I saw it. Expand 37. May 30, 2011 It's a movie about a big hangover, it fallows the premise of the 1st movie. Someone is going to get married. The guys get together to have a couple of drinks, they wake up in the middle of Bangkok and spend the next 24 hours looking for a lost crew member. The movie is very funny and the pictures at the end are even funnier, 38. May 31, 2011 WHY? I so desperately wanted to like this movie. After I came out of the theater I pretty much convinced myself that it was ok. When I got home my wife asked "how was the movie"? Thats when it hit me like a ton of bricks. This movie was awful. Every joke was blatantly recycled from the first movie. Several times they even use the exact same joke and throw in "again" at the end. IE, the group wakes up in a seedy hotel room finding clues as to what happened but still unable to piece the entire picture together, Stu has a tatoo on his face instead of a missing tooth, there's a monkey in the bathroom instead of a tiger, a mute monk instead of a baby, and guess what... their friend is missing!!! They have a revelation "the roof" Stu yells to the group. They all run up to the roof and he's not their. "I cant believe this is happening again" cries Stu. Then Phil says "wait empty your pockets, come on guys you know the drill". And as I sit their feeling a severe sense of Deja Vu I say to myself "Phil I do know the drill". A bunch of other stupid shenanigans take place and about 60 minutes later the movie wraps up, ending the same way the first one did. The only thing I took away from this movie was a little hate towards the first one and towards Todd Phillips as a writer/director. The good news, this movie made enough money already to start penning The Hangover 3 and guess what I know now from the 2nd one not to waste my money. Again if your friend says "Its the same as the first one" HE IS NOT JOKING!!! Expand 39. Dec 17, 2012 Not much to say about this film. It 40. Jul 26, 2011 It seems like Horrible Bosses has taken over to look something forward to as a sequel. This movie lost its luster on this part II. Hangover 1 was just amazing. There was a lot of stupid sexuality that just wasn't funny. Using the monkey for jokes just does not work unless your audience is younger (which it clearly can't be with all the other sexual stuff in this movie). 41. Aug 6, 2011 Moderately funny and a complete Mad Lib rewrite of the first movie. It was unnecessary and certainly not worth the money to see in theaters. Wait for free cable. 42. Jun 10, 2011 Not nearly as funny as part 1, which till date its considered one of the funniest movies of all time. This sequel ripped off everything part one was made of and duplicated the plot, jokes, and premise. Its basically how The Hangover 1 SHOULD NOT HAVE BEEN DONE. Lack of creativity and some boring slow parts made this one a lack luster movie, DVD material. Hangover 1 is still king. 43. Mar 21, 2012 Fun to watch, however, what made the original Hangover so good was the surprise element throughout and the wackiness of Galifianakis. Neither of these elements are fresh in this sequel and as a result the makers felt they needed to push the bar to new extremes, but perhaps pushed it a couple of clicks more than I would have liked them to. 44. Jun 5, 2011 I Can't rate this movie any higher, because though this movie had some laugh out loud moments, for me it was just too much like the first one. I'm sure that the filmmakers wanted to follow the same format, but for me it just doesnt work. I think they over thought this one....... 45. May 31, 2011 The first one was surprising: madcap situations, wacky characters and outrageous humor. The sequel is more of the sameâ 46. May 27, 2011 I can't blame the wolf-pack here. The movie wasn't lacking because of the acting chops. In fact, everyone did a fantastic job of pushing the movie forward as best they could. Special props to Ed Helms for being particularly funny in relatively unfunny moments. However, the prime issue with the movie is that the script itself just wasn't funny. There's hilarity and then there's shock value. Here we aimed for shock as humor and it wasn't convincing. Zach Galifianakis has convincing moments, but the naive character from the first flick is no more, and that's a shame. All in all I laughed here and there, but I laughed more at the photos during the credits. It's a rental movie for a few chuckles, but the writing just isn't enough to warrant a buy. Expand 47. May 28, 2011 It has moments where it's self-referencial, given it's Part 2, but overall, just as funny, witty, and clever as the first! As sequels go, this is a great follow-up! 48. May 31, 2011 I laughed a lot at this movie. Yes, the premise is the same as the first one, but the gags were different and I was entertained the whole way. If I were seeing this film without seeing the first one I would rate it a little higher, but because the characters aren't new and fresh anymore it isn't as good as the first one. There were a couple of hilarious scenes, a lot of mildly amusing scenes, and it has a monkey. Who smokes. I never expect sequels to be as good as the originals so maybe I went into it with lower expectations than other people, but I thought it was a success. Did I mention it has a monkey? :) Expand 49. Nov 26, 2011 It was ok, Too similar to the first and lacks originality however the original parts in it are hilarious and just as good or better. Still a solid comedy none the less. 50. May 28, 2011 This movie had the exact same formula as the first one, just different places and different situations. Which, in a way, was a little bit predictable. I was disappointed that Doug (Justin Bartha) wasn't a part of the problem. I wanted to see him doing some crazy stuff to. It had a lot of funny moments, especially with Mr. Chow (Ken Jeong). Personally, I think that the first one was better, because it was funner. I would prefer to get lost in Las Vegas, then rather being stuck in Bangkok. This one was awesome too. Even with the same structure, it's still interesting to see how these guys will solve their problem. Expand 51. Jul 23, 2011 Control + c. Control + v. There was no creativity in this movie, but it still manages to get a few deserving laughs. The full frontal (Yes, there are multiple of men and women) were disturbing and unneeded. Definitely, the metascore does a good job of representing this movie. 52. May 27, 2011 Maybe it looks like the first, but it is definitely very funny and I really like it. Definitely don't listen critics, they don't know what they saying. Amazing film, should be watched. 53. Jun 23, 2011 This review contains spoilers, click expand to view. It's 'The Hangover' just set in a different place. But then 'The Hangover' was great so why wouldn't this one be? Just as funny as the first even if it was basically the same. It's not a concept which has been done to death yet so it doesn't deserve to be panned for being the same as the first. Lack of involvement of Doug was a disappointment. I thought he may have joined in for some shenanigans. A third might be taking it a step too far but I reckon this one was alright. Expand 54. May 19, 2012 It's kinda sad that I didn't feel that this one was as good as I thought it would be. I loved the 1st movie, when this trailer came, I was so excited. I was with my friends in theaters to watch this. When it was over, we kinda felt that something felt wrong about it, it's just the same **** as the 1st one with a lil change on it. I think that I was lil too hyped for it. So, I went to see it again, by myself this time. Again, I had that feeling, it didn't hold-up as I really want it too. If you already saw the 1st movie, you don't have to see this one. It doesn't hold up as you think or how much you want it to. I felt the same. It really pains me to say it, but this is a skip. Expand 55. Jun 15, 2011 This review contains spoilers, click expand to view. Let me start by saying that I actually liked the original Hangover quite a lot despite going into it with a 'this is gonna suck' mentality, I was delightfully proven wrong on that one and found the first movie to be rich in both childish in your face humour and a pretty decent narrative and story to boot. Then came the sequel, the first thing I have to say is what everyone else has been saying, it's the same damn movie! Just with the setting changed to Bangkok, with every mischevious deed turned up to eleven and with our not-so-heroic punching bags of the first film turned into people we're supposed to sympathise for and want to succeed in escaping. Another issue I had was that while it copies the first film without shame, all the characters from the first have either changed dramatically or have gone missing completely. Alan has changed from being an oddball manchild who was too simple minded to know any better into a raging **** who is selfish, self-centered, out of touch with reality and sometimes borders on being a dangerous psychopath. Stu has changed from the hen-pecked and whipped 'yes dear' boyfriend into a guy who claims to 'struggle with a raging transexual sex demon' (a plot point which comes out of nowhere and never goes anywhere or gets resolved I might add, more on that later) and for some reason has completely abandoned the promising relationsip with the Hooker with a heart of gold from the first film (I think they give an off handed explanation as to why but it's easily missed so I'm just assuming it's because they needed an excuse for the film to take place in Bangkok, cue foreign wedding!). Phil...hardly does anything in this film, I swear the only scene I can remember him being the central focus of outside his introduction at the beginning was him getting shot...that's it, just him getting shot in the arm, and he's supposed to be one of the central characters. Unlike the first film where the characters have their comuppances from their various wrongdoings and get beatings, finger wagging and other very clear explanations that they've been ****s and it's their own damn fault for thinking of Vegas as their own personal playground, no such rebukings come in this film, everything that goes wrong they either get away from scott free or it actually turns out to work in their favour (they start a riot that literally levels part of Bangkok and nothing ever comes as a result of this, it's as if no-one cares about mass death and destruction but I slept with a transexual hooker? I'M A MONSTER!), in the first film, the Wolf Pack are the philandering bastards who did wrong and now must make amends while in the second they're apparantly just normal innocent guys who got mixed up in the perverse trappings of the 'evil city' and must now need to make their way out while still looking like the good guys, something that made me come to realise just how much I did not like the main characters as people at all. Plot points also have a point of just being dropped at a moment's notice or being introduced with no rhyme or reason, for examle: at the beginning it's established that Alan intensesly hates Stu's younger brother-in-law to be, Teddy, to the point where he wants him drugged so he can be taken out of the picture. This would be all fine and good if it weren't for the fact that we're not really given a reason as to why he hates him ('he's not one of the wolf pack' didn't sell me, sorry) and later he either resolves and corrects his hatred of him off-screen and without mention or the writer's just forgot because it's pretty much never mentioned again except for one shouting match which also ends disappointingly, is never mentioned again and only served to highlight more plot holes (like why are they still friends with Alan? He has no redeeming qualities in this movie). Even the way they got to Bangkok is never explained, a lot of clues as to what happened either go literally nowhere or are ommitted until the ending credits (where we finally learn how Teddy lost his finger). Overall, this was an awful film. It had it's funny moments, sure, but most of the time they were just either slapstick violence, immature 'tee hee' laughs that stopped being funny the first time or lazy rehashings or subversions of jokes we saw the first time around. Don't watch if you can help it. 56. Mar 23, 2013 Loved the first film, but was nervous about how a sequel would turn out considering how unnecessary one was. In the end it's good but isn't as funny as the first movie. One big flaw is how it fails to do anything new. The setting is dirtier and grittier, and the content is a lot darker, but most of the movie is just slightly altered content from the first movie. Still I enjoyed and fans of the first will as well. Just don't expect anything we haven't seen before in the first movie. Expand 57. Jun 4, 2011 Like Caddyshack 2 and Animal House 2 and _______________ (pick another studio-driven comedic cash cow) 2, the second Hangover was sentimentally funny and all too forgettable (except The Crying Game allusion...well done there, boys). That said I laughed my ass off a few times and, once again, hardest of all during the closing credits. It was essentially the same template as the first, but I had a couple of beers and popcorn all ready, so I knew what I was getting into. Expand 58. May 28, 2011 Its okay, there is not really anything funny in the dialogue, i think it is mainly just slapstick comedy, the most basic of things. The situations are outrageous so we are supposed to laugh.. and I did if only Ken Jeong could save the whole film.. 59. May 31, 2011 So wanted to like The Hangover Part II but even though it was OK, it just could not live up to the brilliant original. Yes I did laugh out loud many times but the fact that its the exact same movie was so disappointing. This movie proves the point about what is wrong with Hollywood. 60. Dec 3, 2011 Not at all a good as the first one. I generally like when they do not mess too much with a formula that was working but this installement somehow felt quite uninspired. Actually there was not that many places where I lauched. Most of the time I was just feeling annoyed that the bloody bearded idiot actually did the same thing again. 61. Nov 15, 2011 Unfortunately, part II doesn't bring as much laughter as it did the first but it was still enjoyable. Justin Bartha's character didn't miss much as he was the smart one to leave early back to Thailand. The hype of the movie spoiled the true fun as this would've been a great ride if it were to replace the first Hangover. 62. Jun 10, 2011 I didn't expect Part II to be anywhere as good as the original, but it was disappointing nonetheless. I wouldn't have minded the fact that it was basically the same movie, if it had at least been a little bit funny. I was mildly laughing for the first 20 minutes, but after that, when all the hilarity was supposed to start, the film just became boring and hard to watch. The plot stopped making sense, and got really confusing. Too many things were happening, and there wasn't enough comedy to keep me interested. The first movie will forever be one of my favorite comedies, but I'm really hoping to just forget that the second part exists. I didn't rate this too low, because, as I've mentioned before, I found the first 20 minutes funny. Expand 63. May 27, 2011 Don't listen to critics, they're just always depressed. Even though this movies followed the same path as the first one, THAT WAS THE POINT of this movies!!!!!! This movies is far funnier than the first one. Easily. 64. Jul 31, 2011 This review contains spoilers, click expand to view. It is the same thing just in a different location, sometimes that can be good but this movie is not as funny as the first, that had charm and actually good jokes, this has as much charm as a bangkok ladyboy and only a few good jokes, good if you go with your friends that are all guys as there is a point were we find out that Stu has had sex with ladyboy and its just a weird and awkward moment that you don't want to experience on a first date. Expand 65. Jun 3, 2011 The makers of the Hangover have accomplished the seemingly difficult task of creating a film to rival the aforementioned Las Vegian laugh-fest in both quality and originality. The Hangover Part 2's opening scenes will initially spark fears that it will be nothing more than a Zach Galifianakis show, with nine tenths of the gag material coming from him. And despite Galifianakis' impending f oray into the comedic elite, multiple hours of just this clueless and inappropriate hilarity would inevitably become sickening. Nevertheless, once the 'wolfpack' are thrown into their 'hangover', this film picks up where their last one left off. The colourful and erratic nature of Bangkok is the perfect contrast to the setting of their previous wild escapade and the suitably action-accompanied plot line moves along with the velocity of a steam train. However, what is particularly appreciable about this film is the resistance by Phillps et al to not transverse complete rationality - despite gunfights, car chases and drug-dealing monkeys, the basic premise of this film remains within the relative boundaries of reason, particularly when considering the foundations for this film: being part 1. The Hangover Part 2 is by no means a masterpiece. It is the film that fans of its predecessor want to see, and the creators could not ask for more than that. 66. Jun 5, 2011 Nice comedy. Not perfect, but i liked The Hangover II. But some moments are nauseous (I meant scene with transvestite in whorehouse). The movie is funny for one time. 67. Jun 21, 2011 I gave the original a 9, but this one just falls short. They basically remade the first one and though I laughed pretty hard a couple times, most of the time I was bored. 68. Jun 6, 2011 As you might've guessed, this movie is essentially the same as the original. Different city, different wedding, same scenario...but what else could you do with a sequel like this? Much of the humor is unoriginal and borrowed from part I. It just felt stale throughout. Sure there are some funny moments, but part II fails to differentiate itself enough from its predecessor to warrant the price of admission. Part III is already on the way... whose wedding could it be this time? Expand 69. May 28, 2011 The Wolfpack is back. And according the critics thats a bad thing!? I dont think so. After watching The Hangover Part 2 I really have to ask what they were smoking? Just what movie did they see. I'll be honest I had my doubts because the first film was amazing and the success it had was incredible so following the original was always going to be a tall order but I now feel stupid for ever doubting this film. Firstly it's not the carbon-copy of the original - their are refernces made to it but they bring out the laughs remebering what went down. Yes it follws the same structure but I don't see the huge problem people have with that. If it ain't broke why fix it? This time around its Stu's wedding in Thailand and after joining The Wolfpack for a drink the night before the big day they wake up the next morning with a familiar feeling- it happened again. As Stu faces a races against time to get to his wedding they realise that he has lost brides brother, cue the madness and laughs as they try to figure out exactly what happened and where he is whilst evading the city of Bangkok! Ed Helms really steps up in the sequel and is great as Dr. Stu. Zach Galifiniakis is once again in fantastic form as the legendary Alan Garner, Bradley Cooper is once more mr cool Phil but the standout, besides that monkey, is Ken Jeong as the not-so-gangster Leslie Chow. Forget what the critics have said and just take the film for what it is. Its not as fresh and new but it was never going to be what you get is a hilarious sequel full of entertainment and ofcourse the LOL moments the first one was famous for and a marvellous little monkey! What more could you want? Expand 70. Jun 3, 2011 Seems like they took 90 percent of the script from the first movie, added a car chase and replaced the baby with a monkey and a hotel roof for a hotel elevator. That being sai,d I went to see this movie to smile and laugh, as most people do when they go to see a comedy and I did both. Yes it was virtually the same film in a different location but it was STILL very funny. 71. Jun 8, 2011 To say that The Hangover Part II is anywhere close to being as good as the original should be a crime. The original Hangover is a masterpiece when it comes to vulgar jaw dropping comedies, in my opinion it is one of the best comedies in years, but part II failed to measure up to it's previous story. It is what it looks like, a less funny, carbon copy of the first film. Maybe Part III can win back my love for Todd Phillips. Expand 72. May 28, 2011 While this film may not be very original (the critics are correct, it follows the first film to a T), it is by no means a bad or even terrible film. It has it's ups and downs like every comedy, and ultimately ends up being a satisfying experience, but it just doesn't have the charm of the first film because it's nothing new. At the very least, it's worth a rental, and at most, a packed midnight showing with a fun audience. Expand 73. Jun 12, 2011 Very funny sequel to one of the most funniest movie's yet to release in the last couple years. The concept is equal to the first one so, you already will know what could happen or imagine the mysteries of the story. The story is well scripted . But, see the first one if you haven't seen the movies . 74. Jun 5, 2011 This review contains spoilers, click expand to view. Hangover Part II. what a great film, yet another fantastic storyline. People doubted whether or not it could top the previous film, and if the sequel would ruin the originality of the previous film... they thought wrong. Part II is still the same idea, they all go out loose there memory etc etc, but Part II offers so much more comedy and thrill, there is more at stake this time, more too loose. It was great to see the "wolf pack" back together but unfortunately Doug was not in the whole drama again, he went home early, it would have been nice to see him get more involved in the film. This time they do not live the high life glamor like they did in Vegas, they were in Bangkok, there seemed to be a much darker and depressing tone in the movie, they wake up in the grotty, dirty hotel were all the power goes off, they find themselves in the slums of bangkok. the film gets much more graphic, near the beginning and throughout there are strong drug uses and strong sexual actions and nudity. I would say that this film is really a teenage humor, for 15 to 28 maybe but adults will enjoy just as much To sum up this film i would say it is a fantastic must see, its got to be comedy film of the year, its going to win loads of Oscars and just a general fun and fantastic film to watch. A must see film. i give it **** stars (please comment and rate my review :) ) 75. Dec 28, 2011 It's a good film, but sometimes the jokes seem a bit overdone. Even if the film follows the same concept, I really had to laugh often in this movie. Why should you change something which worked perfectly in the past? Also they at least tried to make the film a bit more unexpected. It's a good movie, but don't watch it if you hate the fact that the concept was taken from the first Hangover. 76. May 28, 2011 The plot is exactly the same as the first one and the jokes aren't quite as funny as before. However, if you enjoyed the original, there is plenty to enjoy here. It is not as good as the first film, but it was never going to be able to top that. If you are willing to ignore the identical plot, and just embrace the humour of the film, you will enjoy the Hangover Part 2 immensely, but don't expect it to be as good as the first. Expand 77. Jun 6, 2011 So what if it follows the same formula as the first? So what if the humor is super crude? What did you honestly expect? Once again, this wonderful cast comes together for another crazy night out, and the result is another film that made me laugh, and made me laugh hard. While it just isn't as quite as good as the first, I still thoroughly enjoyed this film, with "Alan" stealing the show again with his every line. Expand 78. Aug 4, 2011 This movie is really hard to review, because, as a stand alone movie, it's brilliant, but as a sequel to the first hangover, it is a complete copy of the first movie with a few different jokes and a new setting. It isn't just similar, it is almost completely identical to the first movie, especially the beginning, where the format is exactly the same. I can't say I didn't enjoy watching the movie, because I did, but if the writers of the the hangover are considering making a third installment, they really need some new ideas. Expand 79. Jun 4, 2011 I really enjoyed this, even more then the first. I would say both movies have about the same amount of good laughs, but unlike 1, part 2 is has so much more adventure going for it. Good laughs in a more interesting city is good to me. 80. Jun 1, 2011 It's not that it's not very funny in parts, because it is, but the lack of originality, in that the structure of the plot is EXACTLY the same (the way they've shot it seems like they were deliberately trying to make it the same, with the beginning, end credits and even the general storyline ), which brings it down as you know exactly what's going to happen before it happens most of the time. It's a shame, but there wasn't really anywhere exciting they could go with the "hangover" concept, should really have just stuck with the first one and used it as a blueprint on how to make other films with seemingly stereotypical ideas and themes original and exciting. Instead, they've cashed in on an idea that seems tired five minute into the film. Expand 81. Jun 19, 2011 I know that probably every person on the world knows by now that The Hangover: Part 2 is a duplicate of the first film and it is true. From the first scene it feels like you are watching the same movie just set in a different location. It does have humorous moments but I think it got a little more disturbing than the first. It was a funny movie but i would stick to the first 82. May 29, 2011 It was very similar to the first, but with a plot twist and two here and there, and many guffaw-worthy moments everywhere, this is the winning formula that made the original so incredible. However, this movie is much more dirty and filled with "adult content", but this does coincide with the movie's darker setting. I loved it, and will be laughing for awhile. 83. Jun 13, 2011 One of the most studid films I have ever seen!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!! I culdn´t wait to the final. But the part I saw was just a patetic tring to emulate the firs one. Just one of the very bad secuels in the movies history! 84. Jun 3, 2011 Not quite on par with the first one, but still very funny and well worth seeing. Great to see the "wolf pack" back together again for another adventure. 85. May 26, 2011 The movie is quite good in its own right, by all means. However, compared to the original, a great degree of flair was lacking in this sequel. Simply, the movie is nowhere near as outrageous as the original was. Now, this may well be due to the original becoming a fixture in American culture, but regardless this new one simply cannot provoke the same fits of laughter for swaths of time as the original one. Truly Ed Helms outdoes himself in this one, and it shows. The other acting is excellent, but Ed helms showed a full range of character traits, and, if for no other reason than his and Ken Jeong's good acting, this is a wonderful movie to see. Expand 86. May 26, 2011 Just let go of expectations, this isn't going to top the original. Once you've gotten past that, the sequel can stand on its own. While not as good, it's funny in it's own right. Several scenes will make you laugh, while a few are actually rather serious. It's generally predictable as they follow the same direction that the first did... which isn't necessarily a bad thing. What was tied into the 2nd from the 1st works, and it works well for the most part. Some parts seemed forced, others flow. If your a fan of the original, go with some friends and enjoy seeing what the cast gets themselves into. It's nothing mind blowing and it isn't going to win any awards, but it's worth seeing. Expand 87. May 26, 2011 A classic example of a good comedy sequel. Truly fantastic. I saw this to make me laugh and make me laugh it did. Just take the film as it is - a comedy sequel. You'll love it. 88. May 28, 2011 This review contains spoilers, click expand to view. This is part 2? of thought it was a remake of the original so really it should be named 'The Hangover 2011'. At the start I thought they were making reference to the original with the phone call and the wedding but as it 'progressed' into the film I realised that I was watching the exact same film for the same amount of money. Trust me the whole film it just the same plot. The 'Wolfpack' get drunk, they lose somebody, they make a deal to find somebody, the deal goes wrong, etc.. it's all the same. (N.B: I am required to hide spoilers although if you saw the original thats basically a major spoiler) 89. May 30, 2011 It was a blast! Sequels are tough. Of course the inevitable comparisons to its predecessor come into play, but 2 delivers. Yes, we all know "who" the characters are, and we all know what Hangover inevitably becomes, and that may take some of the punch away - but that also means if this is your first Hangover, then you'll find it even more of a blast. Wasn't sure the cameo worked, but I g uess its a way to bring back one of the characters involved in one of the funniest situations of the first. Yes, my rating is based on the fact that I fell prey to what I already mentioned - I saw the first and no matter what will always have that "comparison" in the back of my mind. But make no mistake, this is a hilarious sequel and adds to the Hangover cult status. Let's see, the finale should be Zach's turn, right? 90. May 30, 2011 The critics are expecting Shakespeare, which is the only way they can be panning this great sequel. If you set realistic expectations, you will leave the theater completely satisfied. 91. May 30, 2011 I don't get all the negativity. It's a buddy comedy, what did you expect? This isn't some pretentious arthouse film, guys. It made me and my friends laugh loudly the entire way through, and that's all that matters. One of the main complaints I'm hearing is that it was basically the same as the first movie except in a different location. OK, let's analyze this: it's called THE HANGOVER PART II. Meaning, an extension of the first movie. They weren't going to make any radical changes, and they didn't have to. They met my expectations, and it was 10 dollars well spent. Expand 92. May 31, 2011 Cash crop, that's all this movie is now. The fresh are ideas from the first one are recycled. The movie weighs too heavily on the things that worked the first time. The saying "if it ain't broke don't fix it" yeah that applies to everything except movie sequels, or people who are trying to be original. I didn't totally hate it. I mean I didn't expect much. It still had it moments but not even close to the very first Hangover. Expand 93. Jun 1, 2011 The hangover 2 differs from the hangover in that all the crude parts are in the movie and not at end credits. The hangover 2 sticks to the original formula as the first movie and relies on crude potty humor and an overly abudence of F bombs to pull off a few chuckles. Save your money, wait for on demand and in the mean time watch the first one again. 94. Jun 2, 2011 If you've seen the first one... Scratch that - if you've seen the trailer for the first one, you've seen this movie. Lazy, unpleasant, witless but most of all just boring. I think I laughed once. Not nearly good enough. Don't go - you're just encouraging them. 95. Jun 24, 2011 I don't really understand what people's expectations were for this movie, but after reading reviews on here and THEN seeing the film, I thought it was hilarious ! Ton's of over the top dark humor, man/lady private parts, and a monkey ! Although the plot was more or less the same as the first, it still found ways to surprise you. Not a movie for everyone, but if you enjoyed the first movie and aren't sitting there trying to find the flaws you should find yourself satisfied and laughing throughout the most part. Expand 96. Jun 3, 2011 Overall I thought the movie was funny. I know that I laughed just as much or even more during this movie as I did the first Hangover. The concept was the same which brought the movie down a little bit, however, this was a comedy and it brought the laughs I was looking for. 97. Jun 3, 2011 Hilarious movie but had all the same jokes and whatnot. The real disappointment, for me, with this sequel is that I definitely won't be seeing it more than once. I can always pop in the original whenever I want and still find it equally funny. Unfortunately, I won't be seeing this again. Definitely worth seeing once, though. 98. Jun 4, 2011 When all is said and done it is more raunchier than its predecessor and manages to serve up the same level of laughs yet it lacks on what the first one succeeds in, which is the mystery angle. 99. Jun 5, 2011 . All in all the movie was not bad, but I found that it was basically the same as the first movie except for the change in location, who was getting married, and who they were trying to find. It had some pretty funny parts, but I found that it lacked originality when being compared to first one. I didnâ Mixed or average reviews - based on 40 Critics Critic score distribution: 1. Positive: 10 out of 40 2. Negative: 8 out of 40 1. Reviewed by: Ian Buckwalter Jun 1, 2011 2. Reviewed by: David Denby May 30, 2011 3. Reviewed by: Nick Schager May 30, 2011
http://www.metacritic.com/movie/the-hangover-part-ii/user-reviews?dist=neutral&user_review_id=2114827
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or Connect Mothering › Mothering Forums › Pregnancy and Birth › I'm Pregnant › Can I get a mole removed while pregnant? New Posts  All Forums:Forum Nav: Can I get a mole removed while pregnant? post #1 of 6 Thread Starter  I'm 9 weeks pg. And I've got this little mole on my neck that my toddler has grown so fond of, it's like his security blanket. He plays with it so much that it's become very irritated and painful and I need to remove it before it gets worse. It's even bled a couple of times. I'm sure they do a local anesthetic, but I just want to make sure it's completely safe in the first trimester before I get it done. BTW, I feel awful taking this away from my ds, since he seems so attached to it, but he's also very attached to my eyebrows, so I think he'll manage. And yes, I've tried covering it with a band-aid and he just peels it off. post #2 of 6 I've had one removed without the anesthetic and with - didn't make a difference to me. That migh be a thought if you can't get enough safety information for your comfort. post #3 of 6 Actually, I just went to the Dermatologist about a week ago. I'm 32wks pg or so, and he said he could not remove while pg because of the meds they inject into the mole prior to removal. (Now don't go picturing some monstrous mole! It's just a regular ol mole.) The Dr said to wait until after pg. I mentioned how I'd be nursing and asked if that'd pose a problem still, and he said the manufacturer (?) says not to use while nursing but he didnt think it'd cause a problem. I think I'll just wait until after I stop nursing too though. That was my experience. Maybe other Dr's will tell you something different. post #4 of 6 OH MY GOSH!!!! I just skimmed over your post to get the jist of your question before my previous reply post.... But I just now re-read it............. My son has the SAME thing with my moles too!!!!!!!!!!!!!!!!!! :LOL: It started with the one of the back of my neck. He used to use it to go to sleep. Then I just absolutely could not STAND him touching it anymore. He'd want to rub it and stuff. So the rule changed to just touch, dont rub. Then, the neck mole was off limits after a while. But... I also have one on my back that i left him rub in the general area (but not on the actual mole) w/ a flat hand, so it's like i'm getting backrub every night!! :LOL: But... I'm going to get both removed. I do feel bad too... but I'm sure he'll live. And I did want to get the removed anyway before he started all this mole business. He's 4 and this "love of the mole" has been since he was about 1yr old. Maybe I can see about transplanting it to his arm or something. Just kidding!! It's sooooooo funny to find someone else whose son has the same mole attraction. :LOL: post #5 of 6 Sort of related, my friend has a mole right above her breast. Her son would twiddle that during nursing. Now that he is "weanded" he asks: Mom, can I play with your Ball!!!!!! :LOL LoL! Very funny! post #6 of 6 The anesthetic shouldn't be a problem. It's lidocaine. The same thing they would use during an IV start in the hospital with labor. They would use it as well if you needed surgery during your pregnancy (for example an appendix). The real issue is scarring. You are more prone to forming scars during pregnancy and also right after. I would wait until after you are done breastfeeding unless you feel that the mole is changing or have concerns that it is a cancer. New Posts  All Forums:Forum Nav:   Return Home   Back to Forum: I'm Pregnant
http://www.mothering.com/community/t/254293/can-i-get-a-mole-removed-while-pregnant
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