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{"id":2112,"text":"#Causes - Syphilis - 1A6Z\nSyphilis is caused by the bacteria Treponema pallidum. The bacteria can enter one's body if he\/she have close contact with an infected sore, normally during vaginal, anal or oral sex or by sharing sex toys.","entities":[{"id":26773,"label":"Disease_E","start_offset":26,"end_offset":34},{"id":26774,"label":"Cause_E","start_offset":61,"end_offset":79},{"id":26775,"label":"Cause_E","start_offset":81,"end_offset":93},{"id":26776,"label":"Anatomy_E","start_offset":110,"end_offset":114},{"id":26772,"label":"Disease_E","start_offset":10,"end_offset":18}],"relations":[{"id":13723,"from_id":26773,"to_id":26774,"type":"caused_by_R"}],"Comments":[]}
{"id":2113,"text":"#Overview - Syphilis - 1A6Z\nSyphilis is sexually transmitted infection (STI) caused by the spirochete bacterium Treponema pallidum. This disease can be passed to another person through kissing or close physical contact. The infected person is often unaware of the disease and unknowingly passes it on to his or her sexual partner. The sexual behaviour that spreads syphilis can also spread other Sexually transmitted diseases(STD's) like gonorrhea, HIVs.","entities":[{"id":26777,"label":"Disease_E","start_offset":12,"end_offset":20},{"id":26778,"label":"Disease_E","start_offset":28,"end_offset":36},{"id":26781,"label":"Disease_E","start_offset":132,"end_offset":144},{"id":26785,"label":"Disease_E","start_offset":366,"end_offset":374},{"id":26786,"label":"Complication_E","start_offset":397,"end_offset":433},{"id":26787,"label":"Complication_E","start_offset":439,"end_offset":448},{"id":26788,"label":"Complication_E","start_offset":450,"end_offset":454},{"id":26779,"label":"Disease_E","start_offset":40,"end_offset":76},{"id":26780,"label":"Cause_E","start_offset":91,"end_offset":130},{"id":26782,"label":"Riskfactor_E","start_offset":185,"end_offset":192},{"id":26783,"label":"Riskfactor_E","start_offset":202,"end_offset":218},{"id":26784,"label":"Disease_E","start_offset":260,"end_offset":271}],"relations":[{"id":13730,"from_id":26785,"to_id":26787,"type":"has_complication_R"},{"id":13727,"from_id":26781,"to_id":26783,"type":"has_risk_factor_R"},{"id":13726,"from_id":26781,"to_id":26782,"type":"has_risk_factor_R"},{"id":13725,"from_id":26779,"to_id":26780,"type":"caused_by_R"},{"id":13724,"from_id":26778,"to_id":26780,"type":"caused_by_R"},{"id":13729,"from_id":26785,"to_id":26788,"type":"has_complication_R"},{"id":13728,"from_id":26785,"to_id":26786,"type":"has_complication_R"}],"Comments":[]}
{"id":2114,"text":"#Treatment - Syphilis - 1A6Z\nPenicillin, an antibiotic, injected into the muscle, is the best treatment for syphilis. If someone is allergic to penicillin, then healthcare provider may give another antibiotic to take by mouth. In a later stage of disease, more doses of antibiotics will be needed.","entities":[{"id":26789,"label":"Disease_E","start_offset":13,"end_offset":21},{"id":26794,"label":"Medicine_E","start_offset":144,"end_offset":154},{"id":26790,"label":"Medicine_E","start_offset":29,"end_offset":39},{"id":26791,"label":"Medicine_E","start_offset":44,"end_offset":54},{"id":26792,"label":"Anatomy_E","start_offset":74,"end_offset":80},{"id":26793,"label":"Disease_E","start_offset":108,"end_offset":116},{"id":26795,"label":"Anatomy_E","start_offset":220,"end_offset":225}],"relations":[{"id":13732,"from_id":26791,"to_id":26793,"type":"prescribed_for_R"},{"id":13731,"from_id":26790,"to_id":26793,"type":"prescribed_for_R"}],"Comments":[]}
{"id":2115,"text":"#Diagnosis - Syphilis - 1A6Z\nPhysical examination: The doctor will examine genitals. For men, it involves examining the penis, foreskin and urethra (the hole at the end of the penis where urine comes out). For women, it involves an internal examination of the vagina. Both men and women may also have their anus examined. Blood tests: If one is infected with syphilis, then his\/ her body produces antibodies (proteins released as part of immune response) against the syphilis bacteria. Therefore, one way to determine whether one have syphilis is to have a sample of blood tested for the presence of these antibodies. A positive result (antibodies present) indicates that one can either have the infection or used to have it (because the antibodies can remain in the body for years, even after a previous infection was successfully treated). A negative result does not necessarily mean that one does not have syphilis as the antibodies may not be detectable for three months after infection. Person may be advised to repeat the test in three months time. Every pregnant woman should have a blood test for syphilis as the infection can kill unborn or newborn babies. The blood test is usually done during an antenatal appointment at weeks 11–20 of pregnancy. If the test is positive, treatment for both the mother and baby can begin. Venereal Disease Research Laboratory test (VDRL): The VDRL test is a screening test for syphilis. It measures substances, called antibodies, that body may produce if a person comes in contact with the bacteria that causes syphilis. This bacteria is called Treponema pallidum. Swab test- If sores are present, a swab (like a cotton bud) will be used to take a small sample of fluid from the sore. This is then either looked at under a microscope in the clinic or sent to a laboratory for examination.","entities":[{"id":26797,"label":"Diagnosis_E","start_offset":29,"end_offset":49},{"id":26800,"label":"Diagnosis_E","start_offset":233,"end_offset":267},{"id":26801,"label":"Diagnosis_E","start_offset":308,"end_offset":321},{"id":26803,"label":"Disease_E","start_offset":360,"end_offset":368},{"id":26804,"label":"Cause_E","start_offset":468,"end_offset":485},{"id":26806,"label":"Diagnosis_E","start_offset":1168,"end_offset":1182},{"id":26813,"label":"Diagnosis_E","start_offset":1611,"end_offset":1620},{"id":26796,"label":"Disease_E","start_offset":13,"end_offset":21},{"id":26799,"label":"Diagnosis_E","start_offset":106,"end_offset":205},{"id":26802,"label":"Diagnosis_E","start_offset":323,"end_offset":334},{"id":26805,"label":"Disease_E","start_offset":536,"end_offset":544},{"id":26807,"label":"Diagnosis_E","start_offset":1335,"end_offset":1383},{"id":26808,"label":"Diagnosis_E","start_offset":1389,"end_offset":1393},{"id":26809,"label":"Disease_E","start_offset":1423,"end_offset":1431},{"id":26810,"label":"Cause_E","start_offset":1591,"end_offset":1609},{"id":26811,"label":"Cause_E","start_offset":1532,"end_offset":1544},{"id":26812,"label":"Disease_E","start_offset":1557,"end_offset":1565}],"relations":[{"id":13737,"from_id":26796,"to_id":26801,"type":"has_diagnosis_R"},{"id":13736,"from_id":26796,"to_id":26800,"type":"has_diagnosis_R"},{"id":13744,"from_id":26796,"to_id":26813,"type":"has_diagnosis_R"},{"id":13743,"from_id":26812,"to_id":26811,"type":"caused_by_R"},{"id":13739,"from_id":26803,"to_id":26802,"type":"has_diagnosis_R"},{"id":13735,"from_id":26796,"to_id":26799,"type":"has_diagnosis_R"},{"id":13733,"from_id":26796,"to_id":26797,"type":"has_diagnosis_R"},{"id":13742,"from_id":26809,"to_id":26806,"type":"has_diagnosis_R"},{"id":13741,"from_id":26803,"to_id":26804,"type":"caused_by_R"}],"Comments":[]}
{"id":2116,"text":"#Prevention - Syphilis - 1A6Z\nPrevention refers to practices done to prevent the spread of syphilis. Practices may be done by individuals to protect their own health: 1) Protected physical contact through the use of condoms reduces the risk of infection. 2) Promoting sex-education among teen-agers. 3) Providing awareness among the population about their sexual health especially in high risks population (high risks population involves sex workers and their partners, Intravenous drug users, truck drivers, labor migrants, refugees and prisoners).","entities":[{"id":26815,"label":"Disease_E","start_offset":91,"end_offset":99},{"id":26818,"label":"Precaution_E","start_offset":304,"end_offset":549},{"id":26814,"label":"Disease_E","start_offset":14,"end_offset":22},{"id":26816,"label":"Precaution_E","start_offset":171,"end_offset":254},{"id":26817,"label":"Precaution_E","start_offset":259,"end_offset":299}],"relations":[{"id":13745,"from_id":26814,"to_id":26816,"type":"has_precaution_R"},{"id":13747,"from_id":26814,"to_id":26818,"type":"has_precaution_R"},{"id":13746,"from_id":26814,"to_id":26817,"type":"has_precaution_R"}],"Comments":[]}
{"id":2117,"text":"#Symptoms - Syphilis - 1A6Z\nThe symptoms of syphilis are the same for men and women. Also symptoms are mild and thus can be difficult to recognize. The symptoms develop in three stages: Primary syphilis. Secondary syphilis. Tertiary syphilis. Primary syphilis : The initial symptoms of syphilis can appear any time from 10 days to three months after one have been exposed to the infection. The most common symptom is the appearance of a small, painless sore or ulcer (called chancre). The sore will appear on the part of body where the infection was transmitted, typically the penis, vagina, anus, rectum, tongue or lips. Most people only have one sore, but some people can have more. The sores are painless and may be overlooked, so the condition can be spread without realizing that have an infection. The sore will then disappear within two to six weeks and, if the condition is not treated, syphilis will move into its second stage. Secondary syphilis : The symptoms of secondary syphilis will begin a few weeks after the disappearance of the sore. Common symptoms include: A non-itchy skin rash appearing anywhere on the body, but commonly on the palms of the hands or soles of the feet. Tiredness. Headaches. Swollen lymph glands. Less common symptoms include: Fever. Weight loss. Patchy hair loss. Joint pains. These symptoms may disappear within a few weeks, or come and go over a period of months.","entities":[{"id":26820,"label":"Disease_E","start_offset":44,"end_offset":52},{"id":26824,"label":"Disease_E","start_offset":243,"end_offset":259},{"id":26827,"label":"Symptom_E","start_offset":686,"end_offset":803},{"id":26828,"label":"Symptom_E","start_offset":485,"end_offset":621},{"id":26829,"label":"Symptom_E","start_offset":623,"end_offset":684},{"id":26832,"label":"Symptom_E","start_offset":1194,"end_offset":1203},{"id":26835,"label":"Symptom_E","start_offset":1268,"end_offset":1273},{"id":26837,"label":"Symptom_E","start_offset":1288,"end_offset":1304},{"id":26819,"label":"Disease_E","start_offset":12,"end_offset":20},{"id":26821,"label":"Disease_E","start_offset":186,"end_offset":202},{"id":26822,"label":"Disease_E","start_offset":204,"end_offset":222},{"id":26823,"label":"Disease_E","start_offset":224,"end_offset":241},{"id":26825,"label":"Disease_E","start_offset":286,"end_offset":294},{"id":26826,"label":"Symptom_E","start_offset":421,"end_offset":483},{"id":26830,"label":"Disease_E","start_offset":938,"end_offset":956},{"id":26831,"label":"Symptom_E","start_offset":1079,"end_offset":1192},{"id":26833,"label":"Symptom_E","start_offset":1205,"end_offset":1214},{"id":26834,"label":"Symptom_E","start_offset":1216,"end_offset":1236},{"id":26836,"label":"Symptom_E","start_offset":1275,"end_offset":1286},{"id":26838,"label":"Symptom_E","start_offset":1306,"end_offset":1317}],"relations":[{"id":13758,"from_id":26819,"to_id":26837,"type":"has_symptom_R"},{"id":13755,"from_id":26819,"to_id":26834,"type":"has_symptom_R"},{"id":13754,"from_id":26819,"to_id":26833,"type":"has_symptom_R"},{"id":13750,"from_id":26819,"to_id":26829,"type":"has_symptom_R"},{"id":13749,"from_id":26819,"to_id":26828,"type":"has_symptom_R"},{"id":13759,"from_id":26819,"to_id":26838,"type":"has_symptom_R"},{"id":13757,"from_id":26819,"to_id":26836,"type":"has_symptom_R"},{"id":13756,"from_id":26819,"to_id":26835,"type":"has_symptom_R"},{"id":13753,"from_id":26819,"to_id":26832,"type":"has_symptom_R"},{"id":13752,"from_id":26819,"to_id":26831,"type":"has_symptom_R"},{"id":13751,"from_id":26819,"to_id":26827,"type":"has_symptom_R"},{"id":13748,"from_id":26819,"to_id":26826,"type":"has_symptom_R"}],"Comments":[]}