E3_UniProtID
string
Sub_UniProtID
string
Reference
string
Source
string
E3_Gene_Name
string
E3_Sequence
string
E3_Species
string
E3_Subcellular_Location
string
E3_HPA_Expression
string
E3_scRNA_Data
string
E3_PDB_IDs
string
E3_GTEx_expression
string
Sub_Gene_Name
string
Sub_Sequence
string
Sub_Species
string
Sub_Subcellular_Location
string
Sub_HPA_Expression
string
Sub_scRNA_Data
string
Sub_PDB_IDs
string
Sub_GTEx_expression
string
E3_Confidence_Scores
string
E3_Relative_SASA
string
Sub_Confidence_Scores
string
Sub_Relative_SASA
string
E3_Type
string
E3_Complex
string
Complex_name
string
Susbtrate_specificity
string
E3_Known_direct_interactions
string
E3_Substrates
string
PolyUb_Lys
string
C/N_end
string
Associated_E2
string
Self_oligomerization
string
Atypical_AA_ubi
string
E3_Confidence_Scores_Avg
float64
E3_Relative_SASA_Avg
float64
Sub_Confidence_Scores_Avg
float64
Sub_Relative_SASA_Avg
float64
ClusterID
int64
P12830
P78396
null
degron_data
CDH1
MGPWSRSLSALLLLLQVSSWLCQEPEPCHPGFDAESYTFTVPRRHLERGRVLGRVNFEDCTGRQRTAYFSLDTRFKVGTDGVITVKRPLRFHNPQIHFLVYAWDSTYRKFSTKVTLNTVGHHHRPPPHQASVSGIQAELLTFPNSSPGLRRQKRDWVIPPISCPENEKGPFPKNLVQIKSNKDKEGKVFYSITGQGADTPPVGVFIIERETGWLKVTEPLDRERIATYTLFSHAVSSNGNAVEDPMEILITVTDQNDNKPEFTQEVFKGSVMEGALPGTSVMEVTATDADDDVNTYNAAIAYTILSQDPELPDKNMFTINRNTGVISVVTTGLDRESFPTYTLVVQAADLQGEGLSTTATAVITVTDTNDNPPIFNPTTYKGQVPENEANVVITTLKVTDADAPNTPAWEAVYTILNDDGGQFVVTTNPVNNDGILKTAKGLDFEAKQQYILHVAVTNVVPFEVSLTTSTATVTVDVLDVNEAPIFVPPEKRVEVSEDFGVGQEITSYTAQEPDTFMEQKITYRIWRDTANWLEINPDTGAISTRAELDREDFEHVKNSTYTALIIATDNGSPVATGTGTLLLILSDVNDNAPIPEPRTIFFCERNPKPQVINIIDADLPPNTSPFTAELTHGASANWTIQYNDPTQESIILKPKMALEVGDYKINLKLMDNQNKDQVTTLEVSVCDCEGAAGVCRKAQPVEAGLQIPAILGILGGILALLILILLLLLFLRRRAVVKEPLLPPEDDTRDNVYYYDEEGGGEEDQDFDLSQLHRGLDARPEVTRNDVAPTLMSVPRYLPRPANPDEIGNFIDENLKAADTDPTAPPYDSLLVFDYEGSGSEAASLSSLNSSESDKDQDYDYLNEWGNRFKKLADMYGGGEDD
Homo sapiens
Cell junction, adherens junction, Cell membrane, Endosome, Golgi apparatus, trans-Golgi network, Cytoplasm, Cell junction, desmosome
Tissue enhanced (parathyroid)
{'Ciliated cells': '119.1', 'Basal respiratory cells': '71.1', 'Club cells': '97.3', 'Ionocytes': '81.0', 'Mucus glandular cells': '155.0', 'Serous glandular cells': '67.8', 'Gastric mucus-secreting cells': '133.2', 'Proximal enterocytes': '140.9', 'Paneth cells': '125.1', 'Distal enterocytes': '307.5', 'Intestinal goblet cells': '173.5', 'Exocrine glandular cells': '-0.605', 'Basal prostatic cells': '68.3', 'Prostatic glandular cells': '186.7', 'Breast glandular cells': '0.773', 'Breast myoepithelial cells': '0.700', 'Glandular and luminal cells': '313.0', 'Secretory cells': '82.3', 'Basal keratinocytes': '102.5', 'Suprabasal keratinocytes': '162.6', 'Basal squamous epithelial cells': '51.0', 'Squamous epithelial cells': '106.9', 'Alveolar cells type 1': '0.437', 'Alveolar cells type 2': '0.706', 'Salivary duct cells': '95.9', 'Ductal cells': '0.541', 'Hepatocytes': '0.600', 'Cholangiocytes': '129.7', 'Proximal tubular cells': '0.042', 'Distal tubular cells': '0.0', 'Collecting duct cells': '143.9', 'Mesothelial cells': '0.799', 'Sertoli cells': '0.252', 'Granulosa cells': '12.9', 'Enteroendocrine cells': '92.4', 'Pancreatic endocrine cells': '78.1', 'Leydig cells': '0.264', 'Excitatory neurons': '0.7', 'Inhibitory neurons': '1.3', 'Cone photoreceptor cells': '0.0', 'Rod photoreceptor cells': '0.0', 'Bipolar cells': '0.2', 'Horizontal cells': '0.6', 'Astrocytes': '0.6', 'Oligodendrocyte precursor cells': '0.5', 'Oligodendrocytes': '29.9', 'Microglial cells': '0.9', 'Muller glia cells': '0.1', 'Schwann cells': '0.131', 'Spermatogonia': '0.392', 'Spermatocytes': '0.193', 'Early spermatids': '-0.217', 'Late spermatids': '-0.290', 'Oocytes': '16.9', 'Cytotrophoblasts': '119.2', 'Syncytiotrophoblasts': '45.0', 'Extravillous trophoblasts': '24.9', 'Endothelial cells': '6.1', 'Lymphatic endothelial cells': '0.4', 'Cardiomyocytes': '0.135', 'Skeletal myocytes': '0.107', 'Smooth muscle cells': '5.8', 'Adipocytes': '2.1', 'Melanocytes': '0.335', 'Fibroblasts': '6.5', 'Peritubular cells': '0.210', 'Endometrial stromal cells': '27.7', 'Ovarian stromal cells': '0.7', 'Undifferentiated cells': '101.6', 'T-cells': '2.9', 'B-cells': '4.4', 'Plasma cells': '6.1', 'Nk-cells': '0.0', 'Granulocytes': '8.4', 'Monocytes': '0.0', 'Macrophages': '6.0', 'Hofbauer cells': '4.3', 'Kupffer cells': '1.0', 'Dendritic cells': '5.9', 'Langerhans cells': '0.304', 'Erythroid cells': '0.036', 'Adipocytes (Subcutaneous)': '-0.081', 'Adipocytes (Visceral)': '-0.209', 'Breast glandular cells (progenitors)': '0.538', 'Adipocytes (Breast)': '-0.689', 'Colon enterocytes': '0.790', 'Colon enteroendocrine cells': '0.112', 'Enteric glia cells': '-0.048', 'Mitotic cells (Colon)': '0.299', 'Mitotic cells (Heart)': '0.120', 'Podocytes': '-0.118', 'Ascending Loop of Henle cells': '0.475', 'Intercalated cells': '0.212', 'Cholangiocyte': '0.090', 'NK-cells (Liver)': '-0.005', 'Respiratory ciliated cells': '-0.012', 'Mitotic cells (Lung)': '0.071', 'NK-cells (Lung)': '-0.266', 'B-cells (Lung)': '-0.296', 'Alpha cells': '0.270', 'Beta cells': '0.152', 'Prostate glandular cells': '0.764', 'Prostate basal glandular cells': '0.540', 'Urothelial cells': '0.205', 'Keratinocyte (other)': '0.510', 'Keratinocyte (granular)': '0.055', 'Hair cortex cells': '0.080', 'Inner root sheath cells': '0.131', 'Outer root sheath cells': '0.175', 'Sebaceous gland cells': '0.156', 'Eccrine sweat gland cells': '-0.207', 'Adipocytes (Skin)': '-0.244', 'Mitotic cells (Skin)': '0.442', 'Parietal cells': '0.654', 'Chief cells': '0.649', 'Gastric mucous cells': '0.781', 'Gastric enteroendocrine cells': '0.590', 'Mitotic cells (Stomach)': '0.445', 'Parafollicular cells': '0.173', 'Thyroid glandular cells': '0.865', 'Mitotic cells (Thyroid)': '-0.081', 'Adrenal cortex cells': '0.051', 'Adrenal medulla cells': '0.087', 'Mitotic cells (Adrenal gland)': '0.072', 'Minor salivary glandular cells': '0.371', 'Minor salivary gland ductal cells': '-0.142', 'Minor salivary gland basal cells': '0.582', 'Mitotic cells (Minor salivary gland)': '0.567', 'Adipocytes (Minor salivary gland)': '0.050', 'Somatotropes': '0.121', 'Lactotropes': '0.322', 'Gonadotropes': '0.330', 'Corticotropes': '0.180', 'Thyrotropes': '0.496', 'Undifferentiated cells (Pituitary gland)': '-0.108', 'Mitotic cells (Spleen)': '-0.228', 'Platelets': '-0.050', 'Erythrocytes': '-0.158', 'Hematopoietic stem cells': '-0.211', 'B-cells (Spleen)': '0.266', 'NK-cells (Spleen)': '0.309', 'Amygdala excitatory': '1.0', 'Cerebellar inhibitory': '0.9', 'Cge interneuron': '0.7', 'Deep-layer corticothalamic and 6b': '1.5', 'Deep-layer intratelencephalic': '0.7', 'Deep-layer near-projecting': '0.7', 'Eccentric medium spiny neuron': '0.6', 'Hippocampal ca1-3': '1.9', 'Hippocampal ca4': '1.2', 'Hippocampal dentate gyrus': '1.1', 'Lamp5-lhx6 and chandelier': '0.5', 'Lower rhombic lip': '0.8', 'Mammillary body': '0.6', 'Medium spiny neuron': '0.7', 'Mge interneuron': '1.7', 'Midbrain-derived inhibitory': '0.7', 'Miscellaneous': '0.9', 'Splatter': '3.8', 'Thalamic excitatory': '0.5', 'Upper rhombic lip': '0.8', 'Upper-layer intratelencephalic': '0.6', 'Astrocyte': '4.4', 'Bergmann glia': '0.2', 'Central nervous system macrophage': '0.6', 'Choroid plexus epithelial cell': '52.1', 'Committed oligodendrocyte precursor': '41.5', 'Ependymal cell': '4.8', 'Oligodendrocyte': '53.1', 'Oligodendrocyte precursor cell': '2.4', 'Endothelial cell': '0.7', 'Pericyte': '0.3', 'Vascular associated smooth muscle cell': '0.0', 'Fibroblast': '17.4', 'Leukocyte': '1.1', 'Basophil': '0.0', 'Eosinophil': '0.0', 'Neutrophil': '0.0', 'Classical monocyte': '0.0', 'Non-classical monocyte': '0.0', 'Intermediate monocyte': '0.0', 'T-reg': '2.3', 'GdT-cell': '0.0', 'MAIT T-cell': '0.0', 'Memory CD4 T-cell': '0.0', 'Naive CD4 T-cell': '0.1', 'Memory CD8 T-cell': '0.2', 'Naive CD8 T-cell': '0.3', 'Memory B-cell': '0.0', 'Naive B-cell': '0.1', 'Plasmacytoid DC': '46.6', 'Myeloid DC': '8.5', 'NK-cell': '0.1', 'Total PBMC': '0.7', 'Vd2 gdTCR': '0.0', 'Memory CD4 T-cell Th1\\/Th17': '0.1', 'Memory CD4 T-cell Th17': '0.2', 'Memory CD4 T-cell Th2': '2.9', 'Non-Vd2 gdTCR': '0.1', 'Memory CD4 T-cell Th1': '0.3', 'Memory CD4 T-cell TFH': '0.5', 'Terminal effector memory CD4 T-cell': '0.0', 'Central memory CD8 T-cell': '4.8', 'Effector memory CD8 T-cell': '0.0', 'Terminal effector memory CD8 T-cell': '0.6', 'Non-switched memory B-cell': '0.0', 'Plasmablast': '3.3', 'Switched memory B-cell': '0.0', 'Exhausted memory B-cell': '0.7', 'Progenitor cell': '2.3', 'Memory T-reg': '1.3', 'Naive CD4 T-cell activated': '0.3', 'Naive CD8 T-cell activated': '0.6', 'Naive T-reg': '0.1'}
1O6S, 2O72, 2OMT, 2OMU, 2OMV, 2OMX, 2OMY, 2OMZ, 3FF7, 3FF8, 3L6X, 3L6Y, 4ZT1, 4ZTE, 6CXY, 6OLE, 6OLF, 6OLG, 6VEL, 7STZ, 8H62
{'Adipose Tissue': 1.2125261088039867, 'Adrenal Gland': 0.1914223992248062, 'Bladder': 39.2033519047619, 'Blood': 1.340954264800861, 'Blood Vessel': 0.3121561692883895, 'Brain': 0.8550442199091597, 'Breast': 38.54918344226579, 'Cervix Uteri': 23.539115789473684, 'Colon': 43.41292142490372, 'Esophagus': 53.97513367404844, 'Fallopian Tube': 14.900277777777776, 'Heart': 0.119140469221835, 'Kidney': 25.040449438202245, 'Liver': 26.60802654867257, 'Lung': 35.447986366782004, 'Muscle': 0.1378936151930261, 'Nerve': 17.518468982229404, 'Ovary': 3.6515122222222223, 'Pancreas': 56.89676829268293, 'Pituitary': 24.68741660777385, 'Prostate': 61.279967346938776, 'Salivary Gland': 92.01685185185184, 'Skin': 79.77571720232172, 'Small Intestine': 71.7519320855615, 'Spleen': 10.061029045643156, 'Stomach': 58.07813805013927, 'Testis': 0.8144204986149585, 'Thyroid': 135.176797856049, 'Uterus': 1.442593943661972, 'Vagina': 86.52345512820513}
CCNA1
METGFPAIMYPGSFIGGWGEEYLSWEGPGLPDFVFQQQPVESEAMHCSNPKSGVVLATVARGPDACQILTRAPLGQDPPQRTVLGLLTANGQYRRTCGQGITRIRCYSGSENAFPPAGKKALPDCGVQEPPKQGFDIYMDELEQGDRDSCSVREGMAFEDVYEVDTGTLKSDLHFLLDFNTVSPMLVDSSLLSQSEDISSLGTDVINVTEYAEEIYQYLREAEIRHRPKAHYMKKQPDITEGMRTILVDWLVEVGEEYKLRAETLYLAVNFLDRFLSCMSVLRGKLQLVGTAAMLLASKYEEIYPPEVDEFVYITDDTYTKRQLLKMEHLLLKVLAFDLTVPTTNQFLLQYLRRQGVCVRTENLAKYVAELSLLEADPFLKYLPSLIAAAAFCLANYTVNKHFWPETLAAFTGYSLSEIVPCLSELHKAYLDIPHRPQQAIREKYKASKYLCVSLMEPPAVLLLQ
Homo sapiens
Nucleus
Tissue enhanced (parathyroid gland, testis)
{'Ciliated cells': '63.2', 'Basal respiratory cells': '18.7', 'Club cells': '5.9', 'Ionocytes': '12.9', 'Mucus glandular cells': '0.1', 'Serous glandular cells': '0.1', 'Gastric mucus-secreting cells': '0.0', 'Proximal enterocytes': '0.0', 'Paneth cells': '0.0', 'Distal enterocytes': '0.0', 'Intestinal goblet cells': '0.0', 'Exocrine glandular cells': '-0.292', 'Basal prostatic cells': '0.2', 'Prostatic glandular cells': '0.0', 'Breast glandular cells': '0.509', 'Breast myoepithelial cells': '0.452', 'Glandular and luminal cells': '27.7', 'Secretory cells': '36.6', 'Basal keratinocytes': '0.7', 'Suprabasal keratinocytes': '0.2', 'Basal squamous epithelial cells': '0.0', 'Squamous epithelial cells': '0.2', 'Alveolar cells type 1': '-0.056', 'Alveolar cells type 2': '0.039', 'Salivary duct cells': '0.3', 'Ductal cells': '0.360', 'Hepatocytes': '0.004', 'Cholangiocytes': '0.0', 'Proximal tubular cells': '0.204', 'Distal tubular cells': '0.0', 'Collecting duct cells': '0.0', 'Mesothelial cells': '0.084', 'Sertoli cells': '-0.504', 'Granulosa cells': '0.8', 'Enteroendocrine cells': '0.0', 'Pancreatic endocrine cells': '0.0', 'Leydig cells': '-0.521', 'Excitatory neurons': '3.4', 'Inhibitory neurons': '2.8', 'Cone photoreceptor cells': '0.0', 'Rod photoreceptor cells': '0.3', 'Bipolar cells': '0.4', 'Horizontal cells': '1.9', 'Astrocytes': '0.3', 'Oligodendrocyte precursor cells': '0.5', 'Oligodendrocytes': '0.4', 'Microglial cells': '0.0', 'Muller glia cells': '1.4', 'Schwann cells': '0.334', 'Spermatogonia': '-0.286', 'Spermatocytes': '0.177', 'Early spermatids': '0.921', 'Late spermatids': '0.574', 'Oocytes': '0.0', 'Cytotrophoblasts': '0.0', 'Syncytiotrophoblasts': '0.2', 'Extravillous trophoblasts': '0.9', 'Endothelial cells': '0.3', 'Lymphatic endothelial cells': '0.8', 'Cardiomyocytes': '0.221', 'Skeletal myocytes': '-0.194', 'Smooth muscle cells': '0.6', 'Adipocytes': '0.1', 'Melanocytes': '0.056', 'Fibroblasts': '0.9', 'Peritubular cells': '-0.406', 'Endometrial stromal cells': '1.6', 'Ovarian stromal cells': '0.1', 'Undifferentiated cells': '0.0', 'T-cells': '0.3', 'B-cells': '0.1', 'Plasma cells': '0.1', 'Nk-cells': '0.0', 'Granulocytes': '16.8', 'Monocytes': '0.0', 'Macrophages': '0.9', 'Hofbauer cells': '0.1', 'Kupffer cells': '0.0', 'Dendritic cells': '1.2', 'Langerhans cells': '-0.154', 'Erythroid cells': '0.132', 'Adipocytes (Subcutaneous)': '-0.271', 'Adipocytes (Visceral)': '-0.164', 'Breast glandular cells (progenitors)': '0.520', 'Adipocytes (Breast)': '-0.402', 'Colon enterocytes': '-0.027', 'Colon enteroendocrine cells': '0.696', 'Enteric glia cells': '0.286', 'Mitotic cells (Colon)': '-0.036', 'Mitotic cells (Heart)': '0.414', 'Podocytes': '0.044', 'Ascending Loop of Henle cells': '0.154', 'Intercalated cells': '0.003', 'Cholangiocyte': '0.144', 'NK-cells (Liver)': '-0.019', 'Respiratory ciliated cells': '0.771', 'Mitotic cells (Lung)': '0.110', 'NK-cells (Lung)': '0.008', 'B-cells (Lung)': '0.039', 'Alpha cells': '0.234', 'Beta cells': '0.096', 'Prostate glandular cells': '-0.161', 'Prostate basal glandular cells': '-0.003', 'Urothelial cells': '-0.083', 'Keratinocyte (other)': '-0.472', 'Keratinocyte (granular)': '-0.322', 'Hair cortex cells': '0.669', 'Inner root sheath cells': '0.709', 'Outer root sheath cells': '0.611', 'Sebaceous gland cells': '0.139', 'Eccrine sweat gland cells': '0.397', 'Adipocytes (Skin)': '0.376', 'Mitotic cells (Skin)': '0.180', 'Parietal cells': '-0.579', 'Chief cells': '-0.471', 'Gastric mucous cells': '-0.379', 'Gastric enteroendocrine cells': '-0.339', 'Mitotic cells (Stomach)': '-0.042', 'Parafollicular cells': '0.100', 'Thyroid glandular cells': '-0.037', 'Mitotic cells (Thyroid)': '0.161', 'Adrenal cortex cells': '0.040', 'Adrenal medulla cells': '0.254', 'Mitotic cells (Adrenal gland)': '0.118', 'Minor salivary glandular cells': '0.629', 'Minor salivary gland ductal cells': '0.191', 'Minor salivary gland basal cells': '0.136', 'Mitotic cells (Minor salivary gland)': '0.296', 'Adipocytes (Minor salivary gland)': '0.166', 'Somatotropes': '0.253', 'Lactotropes': '0.356', 'Gonadotropes': '-0.039', 'Corticotropes': '0.328', 'Thyrotropes': '0.309', 'Undifferentiated cells (Pituitary gland)': '-0.359', 'Mitotic cells (Spleen)': '0.068', 'Platelets': '0.156', 'Erythrocytes': '0.057', 'Hematopoietic stem cells': '0.209', 'B-cells (Spleen)': '-0.101', 'NK-cells (Spleen)': '-0.078', 'Amygdala excitatory': '5.8', 'Cerebellar inhibitory': '2.8', 'Cge interneuron': '5.1', 'Deep-layer corticothalamic and 6b': '8.2', 'Deep-layer intratelencephalic': '4.0', 'Deep-layer near-projecting': '5.7', 'Eccentric medium spiny neuron': '11.1', 'Hippocampal ca1-3': '7.5', 'Hippocampal ca4': '5.6', 'Hippocampal dentate gyrus': '6.2', 'Lamp5-lhx6 and chandelier': '6.6', 'Lower rhombic lip': '5.6', 'Mammillary body': '3.9', 'Medium spiny neuron': '9.4', 'Mge interneuron': '3.7', 'Midbrain-derived inhibitory': '5.1', 'Miscellaneous': '8.1', 'Splatter': '7.1', 'Thalamic excitatory': '3.5', 'Upper rhombic lip': '1.3', 'Upper-layer intratelencephalic': '5.7', 'Astrocyte': '0.4', 'Bergmann glia': '0.7', 'Central nervous system macrophage': '0.4', 'Choroid plexus epithelial cell': '2.1', 'Committed oligodendrocyte precursor': '0.8', 'Ependymal cell': '25.9', 'Oligodendrocyte': '0.3', 'Oligodendrocyte precursor cell': '0.4', 'Endothelial cell': '0.4', 'Pericyte': '0.7', 'Vascular associated smooth muscle cell': '1.1', 'Fibroblast': '0.3', 'Leukocyte': '0.1', 'Basophil': '226.3', 'Eosinophil': '0.4', 'Neutrophil': '0.3', 'Classical monocyte': '0.0', 'Non-classical monocyte': '0.0', 'Intermediate monocyte': '0.0', 'T-reg': '0.1', 'GdT-cell': '0.0', 'MAIT T-cell': '0.2', 'Memory CD4 T-cell': '0.0', 'Naive CD4 T-cell': '0.0', 'Memory CD8 T-cell': '0.0', 'Naive CD8 T-cell': '0.0', 'Memory B-cell': '0.0', 'Naive B-cell': '0.4', 'Plasmacytoid DC': '0.0', 'Myeloid DC': '0.0', 'NK-cell': '0.0', 'Total PBMC': '2.2', 'Vd2 gdTCR': '0.0', 'Memory CD4 T-cell Th1\\/Th17': '0.0', 'Memory CD4 T-cell Th17': '0.0', 'Memory CD4 T-cell Th2': '0.0', 'Non-Vd2 gdTCR': '0.0', 'Memory CD4 T-cell Th1': '0.0', 'Memory CD4 T-cell TFH': '0.0', 'Terminal effector memory CD4 T-cell': '0.0', 'Central memory CD8 T-cell': '0.0', 'Effector memory CD8 T-cell': '0.0', 'Terminal effector memory CD8 T-cell': '0.0', 'Non-switched memory B-cell': '0.4', 'Plasmablast': '1.3', 'Switched memory B-cell': '0.2', 'Exhausted memory B-cell': '1.6', 'Progenitor cell': '1.4', 'Memory T-reg': '0.0', 'Naive CD4 T-cell activated': '0.0', 'Naive CD8 T-cell activated': '0.1', 'Naive T-reg': '0.0'}
null
{'Adipose Tissue': 0.4920498006644518, 'Adrenal Gland': 0.6211815891472868, 'Bladder': 0.3310395238095238, 'Blood': 4.274904499461787, 'Blood Vessel': 0.6093116404494382, 'Brain': 5.7298269909159725, 'Breast': 0.9459007625272332, 'Cervix Uteri': 4.544005263157895, 'Colon': 0.7117023491655968, 'Esophagus': 0.4226844498269896, 'Fallopian Tube': 13.536555555555555, 'Heart': 0.1997436852497096, 'Kidney': 0.4816573033707865, 'Liver': 0.0884278938053097, 'Lung': 2.2177321280276816, 'Muscle': 0.9621126351183064, 'Nerve': 2.0081823909531504, 'Ovary': 0.8736613888888889, 'Pancreas': 0.0492470579268292, 'Pituitary': 12.370113427561837, 'Prostate': 0.7757826530612245, 'Salivary Gland': 0.8150720987654322, 'Skin': 0.3888909784411277, 'Small Intestine': 0.4413763101604278, 'Spleen': 0.875930580912863, 'Stomach': 0.4098062674094708, 'Testis': 119.19286149584488, 'Thyroid': 1.049834517611026, 'Uterus': 4.181214788732394, 'Vagina': 1.8410341025641024}
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[34.27, 35.6, 40.82, 36.96, 35.89, 37.39, 29.31, 35.57, 28.58, 30.87, 35.19, 33.84, 27.14, 32.26, 28.84, 31.75, 29.72, 28.84, 26.44, 28.41, 30.49, 29.08, 30.72, 26.79, 28.86, 30.94, 36.98, 34.88, 30.93, 34.29, 36.78, 28.95, 28.71, 27.91, 26.66, 26.71, 24.6, 27.22, 24.81, 28.97, 26.24, 24.04, 27.55, 23.43, 28.71, 27.91, 24.05, 30.74, 29.26, 42.21, 35.36, 33.34, 32.84, 27.23, 31.96, 26.22, 27.42, 29.21, 26.46, 31.09, 29.85, 27.13, 37.23, 29.95, 31.87, 28.57, 26.36, 30.31, 26.31, 29.16, 26.18, 26.63, 28.87, 26.36, 30.83, 27.25, 27.98, 32.33, 40.48, 47.68, 52.96, 60.46, 53.91, 67.98, 60.57, 61.41, 56.26, 53.77, 40.72, 46.86, 38.36, 39.31, 33.34, 42.66, 37.23, 30.92, 28.08, 29.46, 27.34, 27.76, 25.93, 29.09, 24.71, 30.11, 23.98, 28.3, 27.46, 28.13, 29.43, 33.88, 32.27, 29.3, 32.83, 36.87, 38.46, 31.48, 37.15, 33.84, 34.13, 34.5, 32.57, 33.24, 30.68, 31.4, 24.72, 32.23, 26.96, 28.62, 28.31, 34.31, 33.63, 31.09, 34.44, 30.46, 36.42, 33.03, 36.89, 41.41, 35.9, 41.48, 37.82, 34.66, 34.71, 30.25, 31.64, 27.32, 31.85, 31.94, 25.57, 26.78, 24.62, 27.35, 27.75, 24.83, 25.46, 27.74, 27.39, 25.02, 29.83, 25.97, 29.83, 31.06, 24.1, 33.17, 30.25, 29.26, 32.44, 31.56, 33.11, 30.87, 38.52, 33.52, 41.21, 38.57, 38.11, 35.65, 37.76, 33.51, 37.08, 38.63, 35.22, 40.9, 39.96, 41.35, 46.22, 48.91, 52.05, 40.97, 45.31, 47.08, 41.79, 38.38, 36.44, 35.02, 33.95, 36.75, 33.54, 37.61, 36.9, 35.32, 39.37, 35.05, 33.67, 47.23, 48.19, 50.0, 53.12, 58.6, 78.8, 85.74, 89.27, 85.99, 88.66, 92.55, 92.35, 93.16, 94.46, 95.3, 95.93, 95.8, 95.64, 95.66, 96.37, 94.67, 91.35, 85.9, 92.09, 94.74, 94.23, 92.74, 93.94, 96.07, 96.29, 94.39, 93.84, 96.44, 95.76, 96.83, 96.61, 96.48, 95.76, 96.03, 97.51, 97.87, 97.45, 97.47, 98.19, 98.35, 98.01, 98.08, 98.51, 98.19, 97.31, 97.46, 97.86, 96.6, 96.19, 96.44, 96.55, 97.73, 97.19, 97.42, 98.0, 98.57, 98.59, 98.44, 98.53, 98.66, 98.52, 97.99, 98.48, 98.41, 98.23, 97.66, 98.12, 98.02, 96.8, 95.55, 96.95, 96.94, 97.23, 97.18, 96.66, 95.15, 96.8, 98.04, 98.24, 98.35, 98.51, 98.54, 98.5, 98.64, 98.75, 98.58, 98.56, 98.5, 98.71, 98.62, 98.38, 97.93, 97.79, 97.97, 97.51, 97.04, 97.43, 97.51, 97.1, 97.57, 97.45, 97.01, 97.24, 97.08, 96.05, 94.39, 92.56, 92.94, 88.88, 93.06, 95.14, 97.3, 97.95, 98.11, 98.09, 98.3, 98.45, 98.42, 98.46, 98.41, 98.17, 98.43, 98.18, 98.31, 98.06, 97.72, 97.02, 96.98, 97.11, 95.73, 96.5, 95.25, 95.49, 96.73, 97.59, 98.06, 97.85, 96.01, 97.71, 97.71, 95.22, 93.53, 95.66, 95.04, 91.37, 91.68, 92.44, 90.39, 92.39, 94.73, 95.52, 95.72, 96.39, 97.21, 97.75, 97.58, 98.16, 98.02, 97.91, 97.24, 98.2, 97.96, 97.29, 97.44, 97.6, 96.0, 92.45, 92.29, 91.76, 94.57, 96.72, 95.55, 94.97, 96.93, 97.28, 97.81, 97.95, 98.12, 98.34, 98.44, 98.3, 98.23, 98.24, 98.06, 96.77, 96.83, 97.2, 95.78, 95.36, 95.12, 94.3, 92.97, 92.53, 92.97, 92.78, 94.81, 94.98, 94.13, 93.74, 95.12, 95.82, 94.2, 92.94, 94.54, 94.86, 96.52, 96.29, 95.6, 95.64, 96.23, 97.3, 96.66, 96.86, 97.43, 97.02, 96.26, 96.38, 96.56, 96.49, 95.3, 94.34, 95.02, 94.76, 93.24, 90.95, 90.07, 90.66, 91.73, 93.76, 94.88, 95.87, 96.68, 96.91, 96.11, 96.25, 96.81, 97.35, 96.28, 95.24, 94.92, 94.01, 95.23, 95.58, 95.55, 96.37, 94.55, 93.94, 92.88, 90.48, 90.75, 90.65, 87.15, 87.68, 86.69, 79.55, 74.4, 50.72]
[1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 0.95, 0.91, 0.95, 0.93, 0.96, 0.95, 0.99, 0.98, 1.0, 0.95, 0.97, 0.99, 0.87, 0.99, 0.97, 0.99, 0.92, 0.95, 0.94, 0.98, 0.98, 1.0, 0.95, 0.98, 0.82, 0.89, 0.85, 0.84, 0.93, 0.92, 0.98, 0.93, 0.95, 0.95, 0.96, 0.99, 0.98, 1.0, 1.0, 1.0, 0.99, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 0.93, 1.0, 0.94, 1.0, 1.0, 0.99, 1.0, 0.99, 1.0, 1.0, 1.0, 1.0, 0.98, 0.98, 0.91, 0.98, 0.89, 1.0, 0.98, 0.97, 0.99, 0.8, 0.98, 0.69, 0.88, 0.82, 0.69, 0.23, 0.32, 0.21, 0.14, 0.4, 0.8, 0.11, 0.49, 0.75, 0.74, 0.32, 0.41, 0.71, 0.62, 0.8, 0.75, 0.81, 0.75, 0.83, 0.87, 0.98, 0.83, 0.97, 0.83, 0.86, 0.83, 0.85, 0.91, 0.82, 0.84, 0.95, 0.9, 0.94, 0.94, 0.98, 0.97, 0.98, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 0.99, 0.97, 0.85, 0.95, 0.95, 0.94, 0.95, 0.91, 0.94, 0.88, 0.86, 0.7, 0.82, 0.48, 0.73, 0.7, 0.8, 0.94, 0.9, 0.93, 0.92, 0.86, 0.87, 0.97, 0.9, 0.98, 1.0, 0.99, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 0.89, 1.0, 0.84, 1.0, 0.99, 0.99, 0.97, 0.98, 1.0, 1.0, 1.0, 0.93, 1.0, 0.85, 0.97, 0.97, 0.99, 0.99, 0.92, 0.95, 0.86, 0.91, 0.88, 0.98, 0.93, 0.93, 0.9, 0.93, 0.96, 0.96, 0.85, 0.86, 0.75, 0.95, 0.93, 0.93, 0.92, 1.0, 0.83, 0.91, 0.88, 0.84, 0.83, 0.93, 0.71, 0.85, 0.5, 0.81, 0.78, 0.49, 0.38, 0.77, 0.83, 0.6, 0.3, 0.62, 0.61, 0.46, 0.05, 0.62, 0.54, 0.13, 0.23, 0.49, 0.01, 0.03, 0.67, 0.61, 0.22, 0.35, 0.19, 0.5, 0.34, 0.57, 0.03, 0.21, 0.81, 0.7, 0.1, 0.76, 0.26, 0.05, 0.41, 0.29, 0.37, 0.03, 0.03, 0.1, 0.06, 0.0, 0.0, 0.03, 0.04, 0.01, 0.03, 0.2, 0.01, 0.12, 0.33, 0.62, 0.21, 0.83, 0.14, 0.39, 0.29, 0.08, 0.0, 0.06, 0.07, 0.02, 0.0, 0.03, 0.17, 0.0, 0.0, 0.03, 0.09, 0.01, 0.02, 0.1, 0.53, 0.03, 0.42, 0.08, 0.66, 0.36, 0.63, 0.49, 0.01, 0.08, 0.08, 0.01, 0.0, 0.02, 0.01, 0.0, 0.01, 0.01, 0.07, 0.0, 0.01, 0.45, 0.45, 0.3, 0.19, 0.86, 0.95, 0.42, 0.17, 0.71, 0.16, 0.44, 0.43, 0.01, 0.12, 0.55, 0.06, 0.01, 0.54, 0.67, 0.64, 0.09, 0.51, 0.39, 0.72, 0.35, 0.02, 0.39, 0.5, 0.1, 0.09, 0.66, 0.19, 0.0, 0.15, 0.69, 0.27, 0.05, 0.65, 0.64, 0.43, 0.1, 0.55, 0.04, 0.08, 0.03, 0.07, 0.11, 0.3, 0.0, 0.01, 0.35, 0.21, 0.0, 0.06, 0.62, 0.44, 0.38, 0.74, 0.26, 0.49, 0.55, 0.51, 0.0, 0.3, 0.07, 0.0, 0.0, 0.23, 0.0, 0.01, 0.01, 0.01, 0.03, 0.06, 0.09, 0.02, 0.18, 0.04, 0.67, 0.16, 0.03, 0.16, 0.6, 0.16, 0.25, 0.15, 0.0, 0.13, 0.07, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.06, 0.1, 0.11, 0.33, 0.42, 0.61, 0.67, 0.17, 0.13, 0.22, 0.81, 0.64, 0.0, 0.29, 0.78, 0.17, 0.09, 0.66, 0.11, 0.36, 0.32, 0.7, 0.5, 0.0, 0.27, 0.48, 0.0, 0.0, 0.33, 0.26, 0.02, 0.09, 0.49, 0.06, 0.03, 0.36, 0.45, 0.04, 0.57, 0.85, 0.28, 0.71, 0.13, 0.21, 0.11, 0.01, 0.26, 0.55, 0.11, 0.03, 0.4, 0.32, 0.73, 0.69, 0.23, 0.49, 0.34, 0.0, 0.08, 0.56, 0.28, 0.88, 0.3, 0.13, 0.79, 0.74, 0.13, 0.6, 0.38, 0.91]
null
Component of an E-cadherin/ catenin adhesion complex composed of at least E-cadherin/CDH1, beta-catenin/CTNNB1 or gamma-catenin/JUP, and potentially alpha-catenin/CTNNA1. Forms a ternary complex composed of ADAM10, CADH1 and EPHA4,
null
null
KLRG1, SPEF1, DLGAP5, AJAP1, RAPGEF2, RAB8B, PIP5K1C, PKP2, TRPV4, CTNNB1, CAV1, DDR1, TBC1D2, CTNNA1, JUP, CTNND1, PSEN1, LIMA1, CDH1, JUP, ADAM10, CADH1 , EPHA4,
null
null
null
null
Homodimer
null
79.91949
0.474025
67.89957
0.547548
1,709
P12830
Q02363
null
degron_data
CDH1
MGPWSRSLSALLLLLQVSSWLCQEPEPCHPGFDAESYTFTVPRRHLERGRVLGRVNFEDCTGRQRTAYFSLDTRFKVGTDGVITVKRPLRFHNPQIHFLVYAWDSTYRKFSTKVTLNTVGHHHRPPPHQASVSGIQAELLTFPNSSPGLRRQKRDWVIPPISCPENEKGPFPKNLVQIKSNKDKEGKVFYSITGQGADTPPVGVFIIERETGWLKVTEPLDRERIATYTLFSHAVSSNGNAVEDPMEILITVTDQNDNKPEFTQEVFKGSVMEGALPGTSVMEVTATDADDDVNTYNAAIAYTILSQDPELPDKNMFTINRNTGVISVVTTGLDRESFPTYTLVVQAADLQGEGLSTTATAVITVTDTNDNPPIFNPTTYKGQVPENEANVVITTLKVTDADAPNTPAWEAVYTILNDDGGQFVVTTNPVNNDGILKTAKGLDFEAKQQYILHVAVTNVVPFEVSLTTSTATVTVDVLDVNEAPIFVPPEKRVEVSEDFGVGQEITSYTAQEPDTFMEQKITYRIWRDTANWLEINPDTGAISTRAELDREDFEHVKNSTYTALIIATDNGSPVATGTGTLLLILSDVNDNAPIPEPRTIFFCERNPKPQVINIIDADLPPNTSPFTAELTHGASANWTIQYNDPTQESIILKPKMALEVGDYKINLKLMDNQNKDQVTTLEVSVCDCEGAAGVCRKAQPVEAGLQIPAILGILGGILALLILILLLLLFLRRRAVVKEPLLPPEDDTRDNVYYYDEEGGGEEDQDFDLSQLHRGLDARPEVTRNDVAPTLMSVPRYLPRPANPDEIGNFIDENLKAADTDPTAPPYDSLLVFDYEGSGSEAASLSSLNSSESDKDQDYDYLNEWGNRFKKLADMYGGGEDD
Homo sapiens
Cell junction, adherens junction, Cell membrane, Endosome, Golgi apparatus, trans-Golgi network, Cytoplasm, Cell junction, desmosome
Tissue enhanced (parathyroid)
{'Ciliated cells': '119.1', 'Basal respiratory cells': '71.1', 'Club cells': '97.3', 'Ionocytes': '81.0', 'Mucus glandular cells': '155.0', 'Serous glandular cells': '67.8', 'Gastric mucus-secreting cells': '133.2', 'Proximal enterocytes': '140.9', 'Paneth cells': '125.1', 'Distal enterocytes': '307.5', 'Intestinal goblet cells': '173.5', 'Exocrine glandular cells': '-0.605', 'Basal prostatic cells': '68.3', 'Prostatic glandular cells': '186.7', 'Breast glandular cells': '0.773', 'Breast myoepithelial cells': '0.700', 'Glandular and luminal cells': '313.0', 'Secretory cells': '82.3', 'Basal keratinocytes': '102.5', 'Suprabasal keratinocytes': '162.6', 'Basal squamous epithelial cells': '51.0', 'Squamous epithelial cells': '106.9', 'Alveolar cells type 1': '0.437', 'Alveolar cells type 2': '0.706', 'Salivary duct cells': '95.9', 'Ductal cells': '0.541', 'Hepatocytes': '0.600', 'Cholangiocytes': '129.7', 'Proximal tubular cells': '0.042', 'Distal tubular cells': '0.0', 'Collecting duct cells': '143.9', 'Mesothelial cells': '0.799', 'Sertoli cells': '0.252', 'Granulosa cells': '12.9', 'Enteroendocrine cells': '92.4', 'Pancreatic endocrine cells': '78.1', 'Leydig cells': '0.264', 'Excitatory neurons': '0.7', 'Inhibitory neurons': '1.3', 'Cone photoreceptor cells': '0.0', 'Rod photoreceptor cells': '0.0', 'Bipolar cells': '0.2', 'Horizontal cells': '0.6', 'Astrocytes': '0.6', 'Oligodendrocyte precursor cells': '0.5', 'Oligodendrocytes': '29.9', 'Microglial cells': '0.9', 'Muller glia cells': '0.1', 'Schwann cells': '0.131', 'Spermatogonia': '0.392', 'Spermatocytes': '0.193', 'Early spermatids': '-0.217', 'Late spermatids': '-0.290', 'Oocytes': '16.9', 'Cytotrophoblasts': '119.2', 'Syncytiotrophoblasts': '45.0', 'Extravillous trophoblasts': '24.9', 'Endothelial cells': '6.1', 'Lymphatic endothelial cells': '0.4', 'Cardiomyocytes': '0.135', 'Skeletal myocytes': '0.107', 'Smooth muscle cells': '5.8', 'Adipocytes': '2.1', 'Melanocytes': '0.335', 'Fibroblasts': '6.5', 'Peritubular cells': '0.210', 'Endometrial stromal cells': '27.7', 'Ovarian stromal cells': '0.7', 'Undifferentiated cells': '101.6', 'T-cells': '2.9', 'B-cells': '4.4', 'Plasma cells': '6.1', 'Nk-cells': '0.0', 'Granulocytes': '8.4', 'Monocytes': '0.0', 'Macrophages': '6.0', 'Hofbauer cells': '4.3', 'Kupffer cells': '1.0', 'Dendritic cells': '5.9', 'Langerhans cells': '0.304', 'Erythroid cells': '0.036', 'Adipocytes (Subcutaneous)': '-0.081', 'Adipocytes (Visceral)': '-0.209', 'Breast glandular cells (progenitors)': '0.538', 'Adipocytes (Breast)': '-0.689', 'Colon enterocytes': '0.790', 'Colon enteroendocrine cells': '0.112', 'Enteric glia cells': '-0.048', 'Mitotic cells (Colon)': '0.299', 'Mitotic cells (Heart)': '0.120', 'Podocytes': '-0.118', 'Ascending Loop of Henle cells': '0.475', 'Intercalated cells': '0.212', 'Cholangiocyte': '0.090', 'NK-cells (Liver)': '-0.005', 'Respiratory ciliated cells': '-0.012', 'Mitotic cells (Lung)': '0.071', 'NK-cells (Lung)': '-0.266', 'B-cells (Lung)': '-0.296', 'Alpha cells': '0.270', 'Beta cells': '0.152', 'Prostate glandular cells': '0.764', 'Prostate basal glandular cells': '0.540', 'Urothelial cells': '0.205', 'Keratinocyte (other)': '0.510', 'Keratinocyte (granular)': '0.055', 'Hair cortex cells': '0.080', 'Inner root sheath cells': '0.131', 'Outer root sheath cells': '0.175', 'Sebaceous gland cells': '0.156', 'Eccrine sweat gland cells': '-0.207', 'Adipocytes (Skin)': '-0.244', 'Mitotic cells (Skin)': '0.442', 'Parietal cells': '0.654', 'Chief cells': '0.649', 'Gastric mucous cells': '0.781', 'Gastric enteroendocrine cells': '0.590', 'Mitotic cells (Stomach)': '0.445', 'Parafollicular cells': '0.173', 'Thyroid glandular cells': '0.865', 'Mitotic cells (Thyroid)': '-0.081', 'Adrenal cortex cells': '0.051', 'Adrenal medulla cells': '0.087', 'Mitotic cells (Adrenal gland)': '0.072', 'Minor salivary glandular cells': '0.371', 'Minor salivary gland ductal cells': '-0.142', 'Minor salivary gland basal cells': '0.582', 'Mitotic cells (Minor salivary gland)': '0.567', 'Adipocytes (Minor salivary gland)': '0.050', 'Somatotropes': '0.121', 'Lactotropes': '0.322', 'Gonadotropes': '0.330', 'Corticotropes': '0.180', 'Thyrotropes': '0.496', 'Undifferentiated cells (Pituitary gland)': '-0.108', 'Mitotic cells (Spleen)': '-0.228', 'Platelets': '-0.050', 'Erythrocytes': '-0.158', 'Hematopoietic stem cells': '-0.211', 'B-cells (Spleen)': '0.266', 'NK-cells (Spleen)': '0.309', 'Amygdala excitatory': '1.0', 'Cerebellar inhibitory': '0.9', 'Cge interneuron': '0.7', 'Deep-layer corticothalamic and 6b': '1.5', 'Deep-layer intratelencephalic': '0.7', 'Deep-layer near-projecting': '0.7', 'Eccentric medium spiny neuron': '0.6', 'Hippocampal ca1-3': '1.9', 'Hippocampal ca4': '1.2', 'Hippocampal dentate gyrus': '1.1', 'Lamp5-lhx6 and chandelier': '0.5', 'Lower rhombic lip': '0.8', 'Mammillary body': '0.6', 'Medium spiny neuron': '0.7', 'Mge interneuron': '1.7', 'Midbrain-derived inhibitory': '0.7', 'Miscellaneous': '0.9', 'Splatter': '3.8', 'Thalamic excitatory': '0.5', 'Upper rhombic lip': '0.8', 'Upper-layer intratelencephalic': '0.6', 'Astrocyte': '4.4', 'Bergmann glia': '0.2', 'Central nervous system macrophage': '0.6', 'Choroid plexus epithelial cell': '52.1', 'Committed oligodendrocyte precursor': '41.5', 'Ependymal cell': '4.8', 'Oligodendrocyte': '53.1', 'Oligodendrocyte precursor cell': '2.4', 'Endothelial cell': '0.7', 'Pericyte': '0.3', 'Vascular associated smooth muscle cell': '0.0', 'Fibroblast': '17.4', 'Leukocyte': '1.1', 'Basophil': '0.0', 'Eosinophil': '0.0', 'Neutrophil': '0.0', 'Classical monocyte': '0.0', 'Non-classical monocyte': '0.0', 'Intermediate monocyte': '0.0', 'T-reg': '2.3', 'GdT-cell': '0.0', 'MAIT T-cell': '0.0', 'Memory CD4 T-cell': '0.0', 'Naive CD4 T-cell': '0.1', 'Memory CD8 T-cell': '0.2', 'Naive CD8 T-cell': '0.3', 'Memory B-cell': '0.0', 'Naive B-cell': '0.1', 'Plasmacytoid DC': '46.6', 'Myeloid DC': '8.5', 'NK-cell': '0.1', 'Total PBMC': '0.7', 'Vd2 gdTCR': '0.0', 'Memory CD4 T-cell Th1\\/Th17': '0.1', 'Memory CD4 T-cell Th17': '0.2', 'Memory CD4 T-cell Th2': '2.9', 'Non-Vd2 gdTCR': '0.1', 'Memory CD4 T-cell Th1': '0.3', 'Memory CD4 T-cell TFH': '0.5', 'Terminal effector memory CD4 T-cell': '0.0', 'Central memory CD8 T-cell': '4.8', 'Effector memory CD8 T-cell': '0.0', 'Terminal effector memory CD8 T-cell': '0.6', 'Non-switched memory B-cell': '0.0', 'Plasmablast': '3.3', 'Switched memory B-cell': '0.0', 'Exhausted memory B-cell': '0.7', 'Progenitor cell': '2.3', 'Memory T-reg': '1.3', 'Naive CD4 T-cell activated': '0.3', 'Naive CD8 T-cell activated': '0.6', 'Naive T-reg': '0.1'}
1O6S, 2O72, 2OMT, 2OMU, 2OMV, 2OMX, 2OMY, 2OMZ, 3FF7, 3FF8, 3L6X, 3L6Y, 4ZT1, 4ZTE, 6CXY, 6OLE, 6OLF, 6OLG, 6VEL, 7STZ, 8H62
{'Adipose Tissue': 1.2125261088039867, 'Adrenal Gland': 0.1914223992248062, 'Bladder': 39.2033519047619, 'Blood': 1.340954264800861, 'Blood Vessel': 0.3121561692883895, 'Brain': 0.8550442199091597, 'Breast': 38.54918344226579, 'Cervix Uteri': 23.539115789473684, 'Colon': 43.41292142490372, 'Esophagus': 53.97513367404844, 'Fallopian Tube': 14.900277777777776, 'Heart': 0.119140469221835, 'Kidney': 25.040449438202245, 'Liver': 26.60802654867257, 'Lung': 35.447986366782004, 'Muscle': 0.1378936151930261, 'Nerve': 17.518468982229404, 'Ovary': 3.6515122222222223, 'Pancreas': 56.89676829268293, 'Pituitary': 24.68741660777385, 'Prostate': 61.279967346938776, 'Salivary Gland': 92.01685185185184, 'Skin': 79.77571720232172, 'Small Intestine': 71.7519320855615, 'Spleen': 10.061029045643156, 'Stomach': 58.07813805013927, 'Testis': 0.8144204986149585, 'Thyroid': 135.176797856049, 'Uterus': 1.442593943661972, 'Vagina': 86.52345512820513}
ID2
MKAFSPVRSVRKNSLSDHSLGISRSKTPVDDPMSLLYNMNDCYSKLKELVPSIPQNKKVSKMEILQHVIDYILDLQIALDSHPTIVSLHHQRPGQNQASRTPLTTLNTDISILSLQASEFPSELMSNDSKALCG
Homo sapiens
Cytoplasm, Nucleus
Tissue enhanced (parathyroid)
{'Ciliated cells': '172.6', 'Basal respiratory cells': '470.7', 'Club cells': '132.4', 'Ionocytes': '363.0', 'Mucus glandular cells': '130.8', 'Serous glandular cells': '87.5', 'Gastric mucus-secreting cells': '188.7', 'Proximal enterocytes': '219.6', 'Paneth cells': '395.3', 'Distal enterocytes': '363.8', 'Intestinal goblet cells': '628.1', 'Exocrine glandular cells': '-0.560', 'Basal prostatic cells': '152.0', 'Prostatic glandular cells': '128.2', 'Breast glandular cells': '0.279', 'Breast myoepithelial cells': '0.364', 'Glandular and luminal cells': '641.5', 'Secretory cells': '45.8', 'Basal keratinocytes': '121.4', 'Suprabasal keratinocytes': '101.1', 'Basal squamous epithelial cells': '99.1', 'Squamous epithelial cells': '90.7', 'Alveolar cells type 1': '0.074', 'Alveolar cells type 2': '-0.181', 'Salivary duct cells': '120.4', 'Ductal cells': '0.543', 'Hepatocytes': '-0.081', 'Cholangiocytes': '270.9', 'Proximal tubular cells': '0.046', 'Distal tubular cells': '365.7', 'Collecting duct cells': '91.4', 'Mesothelial cells': '0.480', 'Sertoli cells': '0.354', 'Granulosa cells': '60.6', 'Enteroendocrine cells': '587.3', 'Pancreatic endocrine cells': '88.3', 'Leydig cells': '0.578', 'Excitatory neurons': '22.7', 'Inhibitory neurons': '13.2', 'Cone photoreceptor cells': '15.3', 'Rod photoreceptor cells': '19.2', 'Bipolar cells': '10.2', 'Horizontal cells': '8.8', 'Astrocytes': '300.3', 'Oligodendrocyte precursor cells': '25.0', 'Oligodendrocytes': '3.0', 'Microglial cells': '15.2', 'Muller glia cells': '494.0', 'Schwann cells': '0.010', 'Spermatogonia': '0.468', 'Spermatocytes': '0.017', 'Early spermatids': '-0.501', 'Late spermatids': '-0.554', 'Oocytes': '37.5', 'Cytotrophoblasts': '260.1', 'Syncytiotrophoblasts': '608.0', 'Extravillous trophoblasts': '139.8', 'Endothelial cells': '253.9', 'Lymphatic endothelial cells': '65.3', 'Cardiomyocytes': '0.222', 'Skeletal myocytes': '0.098', 'Smooth muscle cells': '177.9', 'Adipocytes': '461.3', 'Melanocytes': '0.161', 'Fibroblasts': '304.0', 'Peritubular cells': '0.446', 'Endometrial stromal cells': '334.1', 'Ovarian stromal cells': '346.0', 'Undifferentiated cells': '285.1', 'T-cells': '638.2', 'B-cells': '340.3', 'Plasma cells': '40.5', 'Nk-cells': '1103.4', 'Granulocytes': '688.0', 'Monocytes': '861.2', 'Macrophages': '465.8', 'Hofbauer cells': '814.0', 'Kupffer cells': '357.4', 'Dendritic cells': '197.3', 'Langerhans cells': '0.161', 'Erythroid cells': '0.241', 'Adipocytes (Subcutaneous)': '-0.299', 'Adipocytes (Visceral)': '-0.343', 'Breast glandular cells (progenitors)': '0.131', 'Adipocytes (Breast)': '-0.394', 'Colon enterocytes': '-0.023', 'Colon enteroendocrine cells': '0.217', 'Enteric glia cells': '-0.269', 'Mitotic cells (Colon)': '-0.027', 'Mitotic cells (Heart)': '0.346', 'Podocytes': '0.125', 'Ascending Loop of Henle cells': '0.399', 'Intercalated cells': '0.177', 'Cholangiocyte': '0.135', 'NK-cells (Liver)': '0.110', 'Respiratory ciliated cells': '-0.022', 'Mitotic cells (Lung)': '-0.084', 'NK-cells (Lung)': '0.179', 'B-cells (Lung)': '0.118', 'Alpha cells': '0.331', 'Beta cells': '0.179', 'Prostate glandular cells': '-0.210', 'Prostate basal glandular cells': '-0.083', 'Urothelial cells': '0.209', 'Keratinocyte (other)': '0.173', 'Keratinocyte (granular)': '0.021', 'Hair cortex cells': '0.089', 'Inner root sheath cells': '0.094', 'Outer root sheath cells': '0.130', 'Sebaceous gland cells': '-0.115', 'Eccrine sweat gland cells': '0.151', 'Adipocytes (Skin)': '-0.028', 'Mitotic cells (Skin)': '0.221', 'Parietal cells': '-0.625', 'Chief cells': '-0.682', 'Gastric mucous cells': '-0.407', 'Gastric enteroendocrine cells': '-0.480', 'Mitotic cells (Stomach)': '-0.038', 'Parafollicular cells': '0.044', 'Thyroid glandular cells': '0.277', 'Mitotic cells (Thyroid)': '0.064', 'Adrenal cortex cells': '0.308', 'Adrenal medulla cells': '-0.060', 'Mitotic cells (Adrenal gland)': '-0.183', 'Minor salivary glandular cells': '0.459', 'Minor salivary gland ductal cells': '0.331', 'Minor salivary gland basal cells': '-0.105', 'Mitotic cells (Minor salivary gland)': '-0.054', 'Adipocytes (Minor salivary gland)': '0.047', 'Somatotropes': '-0.420', 'Lactotropes': '-0.312', 'Gonadotropes': '0.003', 'Corticotropes': '0.260', 'Thyrotropes': '0.138', 'Undifferentiated cells (Pituitary gland)': '0.270', 'Mitotic cells (Spleen)': '-0.146', 'Platelets': '0.026', 'Erythrocytes': '0.086', 'Hematopoietic stem cells': '-0.044', 'B-cells (Spleen)': '0.064', 'NK-cells (Spleen)': '0.409', 'Amygdala excitatory': '7.3', 'Cerebellar inhibitory': '1.1', 'Cge interneuron': '45.9', 'Deep-layer corticothalamic and 6b': '14.1', 'Deep-layer intratelencephalic': '38.0', 'Deep-layer near-projecting': '1.2', 'Eccentric medium spiny neuron': '0.7', 'Hippocampal ca1-3': '19.9', 'Hippocampal ca4': '2.3', 'Hippocampal dentate gyrus': '4.3', 'Lamp5-lhx6 and chandelier': '128.3', 'Lower rhombic lip': '11.6', 'Mammillary body': '1.9', 'Medium spiny neuron': '1.0', 'Mge interneuron': '4.5', 'Midbrain-derived inhibitory': '0.9', 'Miscellaneous': '25.5', 'Splatter': '7.2', 'Thalamic excitatory': '7.1', 'Upper rhombic lip': '10.5', 'Upper-layer intratelencephalic': '20.0', 'Astrocyte': '370.6', 'Bergmann glia': '27.5', 'Central nervous system macrophage': '83.8', 'Choroid plexus epithelial cell': '22.5', 'Committed oligodendrocyte precursor': '8.1', 'Ependymal cell': '67.2', 'Oligodendrocyte': '2.0', 'Oligodendrocyte precursor cell': '16.1', 'Endothelial cell': '60.8', 'Pericyte': '2.0', 'Vascular associated smooth muscle cell': '55.7', 'Fibroblast': '13.4', 'Leukocyte': '144.3', 'Basophil': '287.7', 'Eosinophil': '1041.1', 'Neutrophil': '190.1', 'Classical monocyte': '964.7', 'Non-classical monocyte': '367.3', 'Intermediate monocyte': '673.1', 'T-reg': '72.9', 'GdT-cell': '357.7', 'MAIT T-cell': '796.8', 'Memory CD4 T-cell': '108.5', 'Naive CD4 T-cell': '194.3', 'Memory CD8 T-cell': '251.9', 'Naive CD8 T-cell': '288.7', 'Memory B-cell': '3.6', 'Naive B-cell': '3.1', 'Plasmacytoid DC': '26.9', 'Myeloid DC': '1601.3', 'NK-cell': '445.2', 'Total PBMC': '541.9', 'Vd2 gdTCR': '885.2', 'Memory CD4 T-cell Th1\\/Th17': '498.4', 'Memory CD4 T-cell Th17': '161.0', 'Memory CD4 T-cell Th2': '196.6', 'Non-Vd2 gdTCR': '746.5', 'Memory CD4 T-cell Th1': '295.0', 'Memory CD4 T-cell TFH': '62.0', 'Terminal effector memory CD4 T-cell': '435.7', 'Central memory CD8 T-cell': '315.5', 'Effector memory CD8 T-cell': '596.0', 'Terminal effector memory CD8 T-cell': '685.3', 'Non-switched memory B-cell': '62.0', 'Plasmablast': '26.1', 'Switched memory B-cell': '52.2', 'Exhausted memory B-cell': '60.3', 'Progenitor cell': '110.9', 'Memory T-reg': '56.5', 'Naive CD4 T-cell activated': '130.8', 'Naive CD8 T-cell activated': '132.0', 'Naive T-reg': '30.9'}
4AYA
{'Adipose Tissue': 128.83166112956812, 'Adrenal Gland': 110.38519379844962, 'Bladder': 132.41619047619048, 'Blood': 51.72537136706136, 'Blood Vessel': 574.1732958801498, 'Brain': 54.30952838758517, 'Breast': 96.81759694989108, 'Cervix Uteri': 130.0442105263158, 'Colon': 131.62440308087292, 'Esophagus': 71.31968581314878, 'Fallopian Tube': 146.8, 'Heart': 61.44177351916376, 'Kidney': 76.27595505617978, 'Liver': 243.9232743362832, 'Lung': 136.04349480968858, 'Muscle': 8.885902864259029, 'Nerve': 77.88630048465266, 'Ovary': 269.01705555555554, 'Pancreas': 25.716073170731704, 'Pituitary': 79.12572438162545, 'Prostate': 100.58995918367349, 'Salivary Gland': 58.4691975308642, 'Skin': 66.79860475400774, 'Small Intestine': 80.51336898395722, 'Spleen': 91.2613692946058, 'Stomach': 54.69994428969359, 'Testis': 19.914113573407203, 'Thyroid': 133.64964777947932, 'Uterus': 92.56302816901407, 'Vagina': 100.56319871794872}
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73.27, 70.36, 72.63, 72.69, 68.11, 66.06, 60.67, 52.64, 44.07, 48.46, 43.79, 36.31]
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0.54, 0.27, 0.29, 0.51, 0.08, 0.77, 0.06, 0.62, 0.39, 0.34, 0.94, 0.83, 0.46, 0.51, 0.07, 0.17, 0.07, 0.41, 0.14, 0.31, 0.2, 0.36, 0.0, 0.13, 0.59, 0.53, 0.77, 0.2, 0.64, 0.35, 0.0, 0.02, 0.39, 0.18, 0.39, 0.57, 0.63, 0.39, 0.0, 0.32, 0.0, 0.18, 0.03, 0.29, 0.47, 0.55, 0.03, 0.34, 0.2, 0.45, 0.56, 0.17, 0.37, 0.59, 0.01, 0.39, 0.0, 0.39, 0.05, 0.28, 0.07, 0.29, 0.26, 0.64, 0.82, 0.64, 0.63, 0.76, 0.15, 0.39, 0.95, 0.57, 0.28, 0.58, 0.02, 0.43, 0.0, 0.29, 0.09, 0.4, 0.13, 0.49, 0.31, 0.53, 0.32, 0.66, 0.01, 0.71, 0.13, 0.56, 0.54, 0.84, 0.51, 0.06, 0.82, 0.14, 0.54, 0.07, 0.63, 0.05, 0.7, 0.17, 0.75, 0.51, 0.64, 0.36, 0.67, 0.15, 0.12, 0.61, 0.0, 0.33, 0.14, 0.62, 0.2, 0.52, 0.05, 0.14, 0.63, 0.95, 0.85, 0.32, 0.6, 0.1, 0.12, 0.17, 0.17, 0.06, 0.08, 0.41, 0.28, 0.55, 0.49, 0.09, 0.68, 0.23, 0.53, 0.64, 0.52, 0.42, 0.64, 0.64, 0.0, 0.08, 0.44, 0.13, 0.48, 0.52, 0.81, 0.44, 0.0, 0.26, 0.0, 0.21, 0.03, 0.46, 0.27, 0.71, 0.45, 0.06, 0.28, 0.28, 0.4, 0.65, 0.28, 0.46, 0.61, 0.0, 0.36, 0.0, 0.32, 0.01, 0.22, 0.0, 0.05, 0.0, 0.41, 0.46, 0.42, 0.82, 0.48, 0.4, 0.5, 0.17, 0.62, 0.06, 0.32, 0.0, 0.25, 0.0, 0.42, 0.08, 0.41, 0.27, 0.16, 0.04, 0.36, 0.32, 0.2, 0.0, 0.52, 0.04, 0.66, 0.47, 0.52, 0.78, 0.09, 0.77, 0.08, 0.6, 0.0, 0.31, 0.03, 0.58, 0.47, 0.59, 0.44, 0.23, 0.54, 0.1, 0.18, 0.45, 0.0, 0.53, 0.11, 0.59, 0.17, 0.51, 0.01, 0.19, 0.71, 0.77, 0.3, 0.44, 0.08, 0.14, 0.52, 0.05, 0.37, 0.1, 0.42, 0.23, 0.61, 0.43, 0.22, 0.96, 0.54, 0.4, 0.3, 0.07, 0.39, 0.17, 0.43, 0.38, 0.3, 0.8, 0.83, 0.44, 0.03, 0.11, 0.0, 0.23, 0.0, 0.31, 0.0, 0.38, 0.58, 0.51, 0.01, 0.49, 0.13, 0.26, 0.69, 0.46, 0.41, 0.51, 0.06, 0.51, 0.03, 0.38, 0.0, 0.06, 0.0, 0.34, 0.08, 0.53, 0.42, 0.88, 0.25, 0.75, 0.49, 1.0, 0.34, 0.86, 0.48, 0.18, 0.52, 0.01, 0.32, 0.0, 0.19, 0.0, 0.3, 0.05, 0.44, 0.27, 0.43, 0.11, 0.31, 0.39, 0.03, 0.55, 0.04, 0.52, 0.51, 0.64, 0.57, 0.19, 0.68, 0.13, 0.84, 0.06, 0.31, 0.07, 0.69, 0.26, 0.37, 0.53, 0.67, 0.5, 0.56, 0.14, 0.18, 0.47, 0.01, 0.47, 0.15, 0.61, 0.28, 0.2, 0.02, 0.76, 0.55, 0.31, 0.94, 0.22, 0.57, 0.17, 0.4, 0.07, 0.5, 0.31, 0.7, 0.2, 0.14, 0.3, 0.23, 0.58, 0.07, 0.06, 0.55, 0.15, 0.46, 0.43, 0.64, 0.53, 0.0, 0.18, 0.01, 0.23, 0.02, 0.63, 0.33, 0.79, 0.06, 0.38, 0.07, 0.14, 0.23, 0.68, 0.89, 0.29, 0.06, 0.72, 0.92, 0.24, 0.25, 0.0, 0.46, 0.02, 0.21, 0.01, 0.06, 0.0, 0.05, 0.07, 0.61, 0.17, 0.89, 0.72, 0.66, 0.14, 0.52, 0.07, 0.58, 0.01, 0.26, 0.0, 0.13, 0.0, 0.29, 0.04, 0.46, 0.27, 0.28, 0.23, 0.56, 0.32, 0.25, 0.0, 0.33, 0.05, 0.55, 0.5, 0.58, 0.53, 0.04, 0.27, 0.02, 0.04, 0.37, 0.67, 0.74, 0.35, 0.62, 0.54, 0.26, 0.46, 0.0, 0.47, 0.09, 0.45, 0.15, 0.39, 0.05, 0.44, 0.85, 0.56, 0.11, 0.11, 0.35, 0.42, 0.03, 0.32, 0.12, 0.49, 0.19, 0.25, 0.8, 0.6, 0.09, 0.49, 0.57, 0.36, 0.04, 0.35, 0.28, 0.52, 0.39, 0.5, 0.28, 0.93, 0.47, 0.3, 0.47, 0.08, 0.02, 0.18, 0.01, 0.34, 0.23, 0.55, 0.57, 0.91, 0.1, 0.78, 0.52, 0.34, 0.61, 0.24, 0.75, 0.0, 0.2, 0.02, 0.24, 0.0, 0.18, 0.04, 0.44, 0.59, 0.71, 0.29, 0.52, 0.37, 0.5, 0.11, 0.6, 0.02, 0.48, 0.01, 0.16, 0.04, 0.35, 0.66, 0.47, 0.74, 0.14, 0.62, 0.16, 0.77, 0.79, 0.27, 0.93, 0.69, 0.88, 0.88, 0.85, 0.87, 0.91, 0.92, 0.82, 0.63, 0.75, 0.7, 0.7, 0.38, 0.43, 0.64, 0.55, 0.54, 0.59, 0.45, 0.47, 0.5, 0.58, 0.52, 0.61, 0.57, 0.52, 0.68, 0.44, 0.6, 0.61, 0.58, 0.55, 0.5, 0.61, 0.61, 0.86, 0.86, 0.75, 0.91, 0.96, 0.93, 1.0, 0.87, 0.97, 0.91, 0.95, 0.86, 0.98, 0.93, 0.88, 0.59, 0.87, 0.7, 0.67, 0.85, 0.89, 0.88, 0.91, 0.93, 0.88, 0.99, 0.92, 1.0, 0.79, 0.9, 1.0, 0.94, 1.0, 0.97, 0.96, 0.9, 0.63, 0.68, 0.48, 0.54, 0.8, 0.7, 0.7, 0.95, 0.87, 0.77, 0.84, 0.79, 0.89, 0.95, 0.8, 0.77, 0.51, 0.87, 0.7, 0.52, 0.84, 0.91, 0.51, 0.96, 0.79, 0.92, 0.84, 0.21, 0.89, 0.53, 0.52, 0.89, 0.86, 0.26, 0.91, 0.45, 0.68, 0.84, 0.48, 0.44, 0.51, 0.62, 0.28, 0.59, 0.63, 0.57, 0.15, 0.55, 0.66, 0.1, 0.38, 0.74, 0.65, 0.17, 0.43, 0.66, 0.41, 0.8, 0.75, 0.9, 0.93, 0.52, 0.76, 0.89, 0.87, 0.76, 0.92, 0.91, 0.75, 0.61, 0.96, 0.89, 0.73, 0.97, 0.68, 0.87, 0.55, 0.85, 0.77, 0.69, 0.76, 0.98, 0.83, 0.68, 0.82, 0.74, 0.65, 0.96, 0.93, 0.54, 0.64, 0.28, 0.54, 0.52, 0.16, 0.51, 0.88, 0.6, 0.4, 0.88, 0.95, 0.33, 0.56, 0.73, 0.39, 0.06, 0.61, 0.75, 0.47, 0.19, 0.87, 0.7, 0.97, 0.94, 0.97]
[58.8, 63.47, 75.61, 70.62, 65.86, 74.45, 58.51, 69.1, 58.42, 59.3, 61.57, 56.59, 47.73, 42.38, 57.99, 52.49, 46.44, 51.25, 42.31, 55.27, 46.76, 53.69, 51.87, 58.2, 51.02, 49.76, 52.35, 54.45, 59.65, 57.31, 65.68, 67.6, 71.79, 69.02, 70.1, 83.65, 82.89, 89.22, 93.21, 93.43, 93.03, 94.43, 95.78, 92.83, 94.08, 96.16, 95.19, 94.82, 96.35, 97.1, 97.15, 96.81, 97.1, 95.34, 92.43, 91.21, 91.98, 93.51, 95.49, 97.05, 96.97, 98.13, 97.88, 97.88, 98.33, 98.36, 98.38, 98.36, 98.29, 98.26, 98.46, 97.73, 97.47, 96.99, 96.2, 94.26, 94.75, 93.93, 92.17, 89.15, 86.01, 74.31, 65.4, 61.58, 59.53, 56.83, 54.08, 56.89, 51.93, 48.49, 39.02, 45.3, 41.84, 47.21, 55.69, 46.66, 53.75, 54.71, 52.08, 60.25, 57.86, 56.31, 55.95, 58.29, 57.09, 59.92, 57.89, 63.21, 57.18, 66.76, 65.27, 63.88, 62.75, 59.55, 56.96, 52.25, 56.14, 55.33, 46.91, 44.48, 48.31, 44.68, 42.23, 49.35, 46.97, 48.15, 50.59, 52.64, 57.98, 58.92, 53.49, 57.49, 60.33, 54.17]
[0.99, 0.86, 0.91, 0.83, 0.9, 0.9, 0.95, 0.96, 0.93, 0.98, 1.0, 1.0, 0.85, 0.99, 0.86, 0.86, 0.94, 0.86, 0.89, 0.84, 0.89, 0.72, 0.97, 0.85, 0.81, 0.91, 0.51, 0.73, 0.84, 0.74, 0.53, 0.66, 0.63, 0.3, 0.77, 0.22, 0.81, 0.43, 0.63, 0.51, 0.35, 0.26, 0.22, 0.55, 0.28, 0.25, 0.19, 0.64, 0.57, 0.04, 0.72, 0.53, 0.04, 0.36, 0.66, 0.99, 0.46, 0.99, 0.2, 0.55, 0.49, 0.65, 0.29, 0.05, 0.42, 0.51, 0.23, 0.15, 0.59, 0.51, 0.33, 0.49, 0.49, 0.6, 0.42, 0.49, 0.61, 0.5, 0.47, 0.76, 0.69, 0.61, 0.53, 0.69, 0.65, 0.47, 0.57, 0.82, 0.92, 0.75, 0.89, 0.73, 0.95, 0.88, 0.74, 0.88, 0.95, 0.69, 0.8, 0.92, 0.63, 0.88, 0.78, 0.46, 0.77, 0.68, 0.56, 0.48, 0.51, 0.58, 0.41, 0.49, 0.67, 0.61, 0.7, 0.72, 0.64, 0.82, 0.84, 0.86, 0.84, 0.9, 0.89, 0.98, 0.96, 0.94, 1.0, 0.86, 1.0, 0.91, 1.0, 1.0, 1.0, 0.99]
null
Component of an E-cadherin/ catenin adhesion complex composed of at least E-cadherin/CDH1, beta-catenin/CTNNB1 or gamma-catenin/JUP, and potentially alpha-catenin/CTNNA1. Forms a ternary complex composed of ADAM10, CADH1 and EPHA4,
null
null
KLRG1, SPEF1, DLGAP5, AJAP1, RAPGEF2, RAB8B, PIP5K1C, PKP2, TRPV4, CTNNB1, CAV1, DDR1, TBC1D2, CTNNA1, JUP, CTNND1, PSEN1, LIMA1, CDH1, JUP, ADAM10, CADH1 , EPHA4,
null
null
null
null
Homodimer
null
79.91949
0.474025
69.480896
0.680224
2,872
P12830
Q07820
null
degron_data
CDH1
MGPWSRSLSALLLLLQVSSWLCQEPEPCHPGFDAESYTFTVPRRHLERGRVLGRVNFEDCTGRQRTAYFSLDTRFKVGTDGVITVKRPLRFHNPQIHFLVYAWDSTYRKFSTKVTLNTVGHHHRPPPHQASVSGIQAELLTFPNSSPGLRRQKRDWVIPPISCPENEKGPFPKNLVQIKSNKDKEGKVFYSITGQGADTPPVGVFIIERETGWLKVTEPLDRERIATYTLFSHAVSSNGNAVEDPMEILITVTDQNDNKPEFTQEVFKGSVMEGALPGTSVMEVTATDADDDVNTYNAAIAYTILSQDPELPDKNMFTINRNTGVISVVTTGLDRESFPTYTLVVQAADLQGEGLSTTATAVITVTDTNDNPPIFNPTTYKGQVPENEANVVITTLKVTDADAPNTPAWEAVYTILNDDGGQFVVTTNPVNNDGILKTAKGLDFEAKQQYILHVAVTNVVPFEVSLTTSTATVTVDVLDVNEAPIFVPPEKRVEVSEDFGVGQEITSYTAQEPDTFMEQKITYRIWRDTANWLEINPDTGAISTRAELDREDFEHVKNSTYTALIIATDNGSPVATGTGTLLLILSDVNDNAPIPEPRTIFFCERNPKPQVINIIDADLPPNTSPFTAELTHGASANWTIQYNDPTQESIILKPKMALEVGDYKINLKLMDNQNKDQVTTLEVSVCDCEGAAGVCRKAQPVEAGLQIPAILGILGGILALLILILLLLLFLRRRAVVKEPLLPPEDDTRDNVYYYDEEGGGEEDQDFDLSQLHRGLDARPEVTRNDVAPTLMSVPRYLPRPANPDEIGNFIDENLKAADTDPTAPPYDSLLVFDYEGSGSEAASLSSLNSSESDKDQDYDYLNEWGNRFKKLADMYGGGEDD
Homo sapiens
Cell junction, adherens junction, Cell membrane, Endosome, Golgi apparatus, trans-Golgi network, Cytoplasm, Cell junction, desmosome
Tissue enhanced (parathyroid)
{'Ciliated cells': '119.1', 'Basal respiratory cells': '71.1', 'Club cells': '97.3', 'Ionocytes': '81.0', 'Mucus glandular cells': '155.0', 'Serous glandular cells': '67.8', 'Gastric mucus-secreting cells': '133.2', 'Proximal enterocytes': '140.9', 'Paneth cells': '125.1', 'Distal enterocytes': '307.5', 'Intestinal goblet cells': '173.5', 'Exocrine glandular cells': '-0.605', 'Basal prostatic cells': '68.3', 'Prostatic glandular cells': '186.7', 'Breast glandular cells': '0.773', 'Breast myoepithelial cells': '0.700', 'Glandular and luminal cells': '313.0', 'Secretory cells': '82.3', 'Basal keratinocytes': '102.5', 'Suprabasal keratinocytes': '162.6', 'Basal squamous epithelial cells': '51.0', 'Squamous epithelial cells': '106.9', 'Alveolar cells type 1': '0.437', 'Alveolar cells type 2': '0.706', 'Salivary duct cells': '95.9', 'Ductal cells': '0.541', 'Hepatocytes': '0.600', 'Cholangiocytes': '129.7', 'Proximal tubular cells': '0.042', 'Distal tubular cells': '0.0', 'Collecting duct cells': '143.9', 'Mesothelial cells': '0.799', 'Sertoli cells': '0.252', 'Granulosa cells': '12.9', 'Enteroendocrine cells': '92.4', 'Pancreatic endocrine cells': '78.1', 'Leydig cells': '0.264', 'Excitatory neurons': '0.7', 'Inhibitory neurons': '1.3', 'Cone photoreceptor cells': '0.0', 'Rod photoreceptor cells': '0.0', 'Bipolar cells': '0.2', 'Horizontal cells': '0.6', 'Astrocytes': '0.6', 'Oligodendrocyte precursor cells': '0.5', 'Oligodendrocytes': '29.9', 'Microglial cells': '0.9', 'Muller glia cells': '0.1', 'Schwann cells': '0.131', 'Spermatogonia': '0.392', 'Spermatocytes': '0.193', 'Early spermatids': '-0.217', 'Late spermatids': '-0.290', 'Oocytes': '16.9', 'Cytotrophoblasts': '119.2', 'Syncytiotrophoblasts': '45.0', 'Extravillous trophoblasts': '24.9', 'Endothelial cells': '6.1', 'Lymphatic endothelial cells': '0.4', 'Cardiomyocytes': '0.135', 'Skeletal myocytes': '0.107', 'Smooth muscle cells': '5.8', 'Adipocytes': '2.1', 'Melanocytes': '0.335', 'Fibroblasts': '6.5', 'Peritubular cells': '0.210', 'Endometrial stromal cells': '27.7', 'Ovarian stromal cells': '0.7', 'Undifferentiated cells': '101.6', 'T-cells': '2.9', 'B-cells': '4.4', 'Plasma cells': '6.1', 'Nk-cells': '0.0', 'Granulocytes': '8.4', 'Monocytes': '0.0', 'Macrophages': '6.0', 'Hofbauer cells': '4.3', 'Kupffer cells': '1.0', 'Dendritic cells': '5.9', 'Langerhans cells': '0.304', 'Erythroid cells': '0.036', 'Adipocytes (Subcutaneous)': '-0.081', 'Adipocytes (Visceral)': '-0.209', 'Breast glandular cells (progenitors)': '0.538', 'Adipocytes (Breast)': '-0.689', 'Colon enterocytes': '0.790', 'Colon enteroendocrine cells': '0.112', 'Enteric glia cells': '-0.048', 'Mitotic cells (Colon)': '0.299', 'Mitotic cells (Heart)': '0.120', 'Podocytes': '-0.118', 'Ascending Loop of Henle cells': '0.475', 'Intercalated cells': '0.212', 'Cholangiocyte': '0.090', 'NK-cells (Liver)': '-0.005', 'Respiratory ciliated cells': '-0.012', 'Mitotic cells (Lung)': '0.071', 'NK-cells (Lung)': '-0.266', 'B-cells (Lung)': '-0.296', 'Alpha cells': '0.270', 'Beta cells': '0.152', 'Prostate glandular cells': '0.764', 'Prostate basal glandular cells': '0.540', 'Urothelial cells': '0.205', 'Keratinocyte (other)': '0.510', 'Keratinocyte (granular)': '0.055', 'Hair cortex cells': '0.080', 'Inner root sheath cells': '0.131', 'Outer root sheath cells': '0.175', 'Sebaceous gland cells': '0.156', 'Eccrine sweat gland cells': '-0.207', 'Adipocytes (Skin)': '-0.244', 'Mitotic cells (Skin)': '0.442', 'Parietal cells': '0.654', 'Chief cells': '0.649', 'Gastric mucous cells': '0.781', 'Gastric enteroendocrine cells': '0.590', 'Mitotic cells (Stomach)': '0.445', 'Parafollicular cells': '0.173', 'Thyroid glandular cells': '0.865', 'Mitotic cells (Thyroid)': '-0.081', 'Adrenal cortex cells': '0.051', 'Adrenal medulla cells': '0.087', 'Mitotic cells (Adrenal gland)': '0.072', 'Minor salivary glandular cells': '0.371', 'Minor salivary gland ductal cells': '-0.142', 'Minor salivary gland basal cells': '0.582', 'Mitotic cells (Minor salivary gland)': '0.567', 'Adipocytes (Minor salivary gland)': '0.050', 'Somatotropes': '0.121', 'Lactotropes': '0.322', 'Gonadotropes': '0.330', 'Corticotropes': '0.180', 'Thyrotropes': '0.496', 'Undifferentiated cells (Pituitary gland)': '-0.108', 'Mitotic cells (Spleen)': '-0.228', 'Platelets': '-0.050', 'Erythrocytes': '-0.158', 'Hematopoietic stem cells': '-0.211', 'B-cells (Spleen)': '0.266', 'NK-cells (Spleen)': '0.309', 'Amygdala excitatory': '1.0', 'Cerebellar inhibitory': '0.9', 'Cge interneuron': '0.7', 'Deep-layer corticothalamic and 6b': '1.5', 'Deep-layer intratelencephalic': '0.7', 'Deep-layer near-projecting': '0.7', 'Eccentric medium spiny neuron': '0.6', 'Hippocampal ca1-3': '1.9', 'Hippocampal ca4': '1.2', 'Hippocampal dentate gyrus': '1.1', 'Lamp5-lhx6 and chandelier': '0.5', 'Lower rhombic lip': '0.8', 'Mammillary body': '0.6', 'Medium spiny neuron': '0.7', 'Mge interneuron': '1.7', 'Midbrain-derived inhibitory': '0.7', 'Miscellaneous': '0.9', 'Splatter': '3.8', 'Thalamic excitatory': '0.5', 'Upper rhombic lip': '0.8', 'Upper-layer intratelencephalic': '0.6', 'Astrocyte': '4.4', 'Bergmann glia': '0.2', 'Central nervous system macrophage': '0.6', 'Choroid plexus epithelial cell': '52.1', 'Committed oligodendrocyte precursor': '41.5', 'Ependymal cell': '4.8', 'Oligodendrocyte': '53.1', 'Oligodendrocyte precursor cell': '2.4', 'Endothelial cell': '0.7', 'Pericyte': '0.3', 'Vascular associated smooth muscle cell': '0.0', 'Fibroblast': '17.4', 'Leukocyte': '1.1', 'Basophil': '0.0', 'Eosinophil': '0.0', 'Neutrophil': '0.0', 'Classical monocyte': '0.0', 'Non-classical monocyte': '0.0', 'Intermediate monocyte': '0.0', 'T-reg': '2.3', 'GdT-cell': '0.0', 'MAIT T-cell': '0.0', 'Memory CD4 T-cell': '0.0', 'Naive CD4 T-cell': '0.1', 'Memory CD8 T-cell': '0.2', 'Naive CD8 T-cell': '0.3', 'Memory B-cell': '0.0', 'Naive B-cell': '0.1', 'Plasmacytoid DC': '46.6', 'Myeloid DC': '8.5', 'NK-cell': '0.1', 'Total PBMC': '0.7', 'Vd2 gdTCR': '0.0', 'Memory CD4 T-cell Th1\\/Th17': '0.1', 'Memory CD4 T-cell Th17': '0.2', 'Memory CD4 T-cell Th2': '2.9', 'Non-Vd2 gdTCR': '0.1', 'Memory CD4 T-cell Th1': '0.3', 'Memory CD4 T-cell TFH': '0.5', 'Terminal effector memory CD4 T-cell': '0.0', 'Central memory CD8 T-cell': '4.8', 'Effector memory CD8 T-cell': '0.0', 'Terminal effector memory CD8 T-cell': '0.6', 'Non-switched memory B-cell': '0.0', 'Plasmablast': '3.3', 'Switched memory B-cell': '0.0', 'Exhausted memory B-cell': '0.7', 'Progenitor cell': '2.3', 'Memory T-reg': '1.3', 'Naive CD4 T-cell activated': '0.3', 'Naive CD8 T-cell activated': '0.6', 'Naive T-reg': '0.1'}
1O6S, 2O72, 2OMT, 2OMU, 2OMV, 2OMX, 2OMY, 2OMZ, 3FF7, 3FF8, 3L6X, 3L6Y, 4ZT1, 4ZTE, 6CXY, 6OLE, 6OLF, 6OLG, 6VEL, 7STZ, 8H62
{'Adipose Tissue': 1.2125261088039867, 'Adrenal Gland': 0.1914223992248062, 'Bladder': 39.2033519047619, 'Blood': 1.340954264800861, 'Blood Vessel': 0.3121561692883895, 'Brain': 0.8550442199091597, 'Breast': 38.54918344226579, 'Cervix Uteri': 23.539115789473684, 'Colon': 43.41292142490372, 'Esophagus': 53.97513367404844, 'Fallopian Tube': 14.900277777777776, 'Heart': 0.119140469221835, 'Kidney': 25.040449438202245, 'Liver': 26.60802654867257, 'Lung': 35.447986366782004, 'Muscle': 0.1378936151930261, 'Nerve': 17.518468982229404, 'Ovary': 3.6515122222222223, 'Pancreas': 56.89676829268293, 'Pituitary': 24.68741660777385, 'Prostate': 61.279967346938776, 'Salivary Gland': 92.01685185185184, 'Skin': 79.77571720232172, 'Small Intestine': 71.7519320855615, 'Spleen': 10.061029045643156, 'Stomach': 58.07813805013927, 'Testis': 0.8144204986149585, 'Thyroid': 135.176797856049, 'Uterus': 1.442593943661972, 'Vagina': 86.52345512820513}
MCL1
MFGLKRNAVIGLNLYCGGAGLGAGSGGATRPGGRLLATEKEASARREIGGGEAGAVIGGSAGASPPSTLTPDSRRVARPPPIGAEVPDVTATPARLLFFAPTRRAAPLEEMEAPAADAIMSPEEELDGYEPEPLGKRPAVLPLLELVGESGNNTSTDGSLPSTPPPAEEEEDELYRQSLEIISRYLREQATGAKDTKPMGRSGATSRKALETLRRVGDGVQRNHETAFQGMLRKLDIKNEDDVKSLSRVMIHVFSDGVTNWGRIVTLISFGAFVAKHLKTINQESCIEPLAESITDVLVRTKRDWLVKQRGWDGFVEFFHVEDLEGGIRNVLLAFAGVAGVGAGLAYLIR
Homo sapiens
Membrane, Cytoplasm, Mitochondrion, Nucleus, nucleoplasm
Tissue enhanced (bone)
{'Ciliated cells': '155.7', 'Basal respiratory cells': '139.9', 'Club cells': '201.5', 'Ionocytes': '134.7', 'Mucus glandular cells': '361.3', 'Serous glandular cells': '187.2', 'Gastric mucus-secreting cells': '212.2', 'Proximal enterocytes': '215.8', 'Paneth cells': '149.9', 'Distal enterocytes': '316.1', 'Intestinal goblet cells': '270.1', 'Exocrine glandular cells': '-0.670', 'Basal prostatic cells': '317.8', 'Prostatic glandular cells': '82.7', 'Breast glandular cells': '0.457', 'Breast myoepithelial cells': '0.594', 'Glandular and luminal cells': '352.7', 'Secretory cells': '198.7', 'Basal keratinocytes': '375.5', 'Suprabasal keratinocytes': '443.7', 'Basal squamous epithelial cells': '393.8', 'Squamous epithelial cells': '351.8', 'Alveolar cells type 1': '0.142', 'Alveolar cells type 2': '0.031', 'Salivary duct cells': '371.2', 'Ductal cells': '0.640', 'Hepatocytes': '0.175', 'Cholangiocytes': '221.3', 'Proximal tubular cells': '0.248', 'Distal tubular cells': '27.7', 'Collecting duct cells': '37.0', 'Mesothelial cells': '-0.075', 'Sertoli cells': '0.344', 'Granulosa cells': '411.0', 'Enteroendocrine cells': '199.5', 'Pancreatic endocrine cells': '47.5', 'Leydig cells': '0.522', 'Excitatory neurons': '6.3', 'Inhibitory neurons': '5.2', 'Cone photoreceptor cells': '52.7', 'Rod photoreceptor cells': '93.5', 'Bipolar cells': '48.7', 'Horizontal cells': '35.9', 'Astrocytes': '11.8', 'Oligodendrocyte precursor cells': '9.4', 'Oligodendrocytes': '6.4', 'Microglial cells': '28.6', 'Muller glia cells': '130.5', 'Schwann cells': '0.111', 'Spermatogonia': '0.466', 'Spermatocytes': '0.199', 'Early spermatids': '-0.204', 'Late spermatids': '-0.444', 'Oocytes': '18.4', 'Cytotrophoblasts': '110.3', 'Syncytiotrophoblasts': '309.7', 'Extravillous trophoblasts': '217.3', 'Endothelial cells': '237.3', 'Lymphatic endothelial cells': '312.8', 'Cardiomyocytes': '0.237', 'Skeletal myocytes': '-0.230', 'Smooth muscle cells': '231.1', 'Adipocytes': '365.2', 'Melanocytes': '0.133', 'Fibroblasts': '292.6', 'Peritubular cells': '0.423', 'Endometrial stromal cells': '318.3', 'Ovarian stromal cells': '152.0', 'Undifferentiated cells': '135.6', 'T-cells': '498.2', 'B-cells': '316.5', 'Plasma cells': '716.2', 'Nk-cells': '393.9', 'Granulocytes': '843.2', 'Monocytes': '1334.1', 'Macrophages': '727.7', 'Hofbauer cells': '487.7', 'Kupffer cells': '411.9', 'Dendritic cells': '726.8', 'Langerhans cells': '0.006', 'Erythroid cells': '0.014', 'Adipocytes (Subcutaneous)': '-0.388', 'Adipocytes (Visceral)': '0.157', 'Breast glandular cells (progenitors)': '0.400', 'Adipocytes (Breast)': '-0.643', 'Colon enterocytes': '-0.008', 'Colon enteroendocrine cells': '0.133', 'Enteric glia cells': '-0.203', 'Mitotic cells (Colon)': '0.158', 'Mitotic cells (Heart)': '0.386', 'Podocytes': '0.027', 'Ascending Loop of Henle cells': '0.144', 'Intercalated cells': '-0.056', 'Cholangiocyte': '0.381', 'NK-cells (Liver)': '-0.274', 'Respiratory ciliated cells': '0.005', 'Mitotic cells (Lung)': '-0.088', 'NK-cells (Lung)': '0.111', 'B-cells (Lung)': '0.107', 'Alpha cells': '0.282', 'Beta cells': '0.166', 'Prostate glandular cells': '-0.369', 'Prostate basal glandular cells': '0.058', 'Urothelial cells': '0.208', 'Keratinocyte (other)': '0.165', 'Keratinocyte (granular)': '-0.059', 'Hair cortex cells': '-0.184', 'Inner root sheath cells': '-0.122', 'Outer root sheath cells': '-0.076', 'Sebaceous gland cells': '-0.116', 'Eccrine sweat gland cells': '-0.033', 'Adipocytes (Skin)': '-0.155', 'Mitotic cells (Skin)': '0.099', 'Parietal cells': '-0.551', 'Chief cells': '-0.486', 'Gastric mucous cells': '-0.321', 'Gastric enteroendocrine cells': '-0.369', 'Mitotic cells (Stomach)': '-0.029', 'Parafollicular cells': '0.016', 'Thyroid glandular cells': '0.007', 'Mitotic cells (Thyroid)': '0.119', 'Adrenal cortex cells': '0.176', 'Adrenal medulla cells': '-0.019', 'Mitotic cells (Adrenal gland)': '0.093', 'Minor salivary glandular cells': '0.636', 'Minor salivary gland ductal cells': '0.048', 'Minor salivary gland basal cells': '0.401', 'Mitotic cells (Minor salivary gland)': '0.462', 'Adipocytes (Minor salivary gland)': '0.231', 'Somatotropes': '-0.347', 'Lactotropes': '-0.410', 'Gonadotropes': '-0.039', 'Corticotropes': '-0.114', 'Thyrotropes': '-0.067', 'Undifferentiated cells (Pituitary gland)': '0.204', 'Mitotic cells (Spleen)': '0.088', 'Platelets': '0.156', 'Erythrocytes': '-0.043', 'Hematopoietic stem cells': '0.013', 'B-cells (Spleen)': '0.101', 'NK-cells (Spleen)': '0.233', 'Amygdala excitatory': '8.2', 'Cerebellar inhibitory': '9.8', 'Cge interneuron': '9.7', 'Deep-layer corticothalamic and 6b': '9.5', 'Deep-layer intratelencephalic': '8.5', 'Deep-layer near-projecting': '6.7', 'Eccentric medium spiny neuron': '10.8', 'Hippocampal ca1-3': '8.9', 'Hippocampal ca4': '5.9', 'Hippocampal dentate gyrus': '7.5', 'Lamp5-lhx6 and chandelier': '7.9', 'Lower rhombic lip': '5.1', 'Mammillary body': '5.6', 'Medium spiny neuron': '7.5', 'Mge interneuron': '8.0', 'Midbrain-derived inhibitory': '16.8', 'Miscellaneous': '10.0', 'Splatter': '8.0', 'Thalamic excitatory': '8.0', 'Upper rhombic lip': '13.2', 'Upper-layer intratelencephalic': '8.0', 'Astrocyte': '40.9', 'Bergmann glia': '14.2', 'Central nervous system macrophage': '47.0', 'Choroid plexus epithelial cell': '26.1', 'Committed oligodendrocyte precursor': '13.8', 'Ependymal cell': '22.6', 'Oligodendrocyte': '11.5', 'Oligodendrocyte precursor cell': '13.6', 'Endothelial cell': '125.3', 'Pericyte': '32.7', 'Vascular associated smooth muscle cell': '61.1', 'Fibroblast': '46.1', 'Leukocyte': '128.3', 'Basophil': '197.9', 'Eosinophil': '51.9', 'Neutrophil': '2173.5', 'Classical monocyte': '5002.1', 'Non-classical monocyte': '1782.9', 'Intermediate monocyte': '446.6', 'T-reg': '152.7', 'GdT-cell': '15.0', 'MAIT T-cell': '204.8', 'Memory CD4 T-cell': '19.1', 'Naive CD4 T-cell': '1084.0', 'Memory CD8 T-cell': '16.6', 'Naive CD8 T-cell': '929.5', 'Memory B-cell': '12.6', 'Naive B-cell': '452.6', 'Plasmacytoid DC': '115.0', 'Myeloid DC': '479.2', 'NK-cell': '983.4', 'Total PBMC': '280.7', 'Vd2 gdTCR': '171.8', 'Memory CD4 T-cell Th1\\/Th17': '1242.0', 'Memory CD4 T-cell Th17': '1070.7', 'Memory CD4 T-cell Th2': '1117.5', 'Non-Vd2 gdTCR': '142.1', 'Memory CD4 T-cell Th1': '897.5', 'Memory CD4 T-cell TFH': '838.0', 'Terminal effector memory CD4 T-cell': '161.6', 'Central memory CD8 T-cell': '190.7', 'Effector memory CD8 T-cell': '173.4', 'Terminal effector memory CD8 T-cell': '144.5', 'Non-switched memory B-cell': '124.7', 'Plasmablast': '248.3', 'Switched memory B-cell': '145.6', 'Exhausted memory B-cell': '153.7', 'Progenitor cell': '85.4', 'Memory T-reg': '852.7', 'Naive CD4 T-cell activated': '1072.1', 'Naive CD8 T-cell activated': '1057.4', 'Naive T-reg': '935.2'}
2KBW, 2MHS, 2NL9, 2NLA, 2PQK, 3D7V, 3IO9, 3KJ0, 3KJ1, 3KJ2, 3KZ0, 3MK8, 3PK1, 3TWU, 3WIX, 3WIY, 4BPI, 4BPJ, 4HW2, 4HW3, 4HW4, 4OQ5, 4OQ6, 4WGI, 4WMR, 4WMS, 4WMT, 4WMU, 4WMV, 4WMW, 4WMX, 4ZBF, 4ZBI, 5C3F, 5C6H, 5FC4, 5FDO, 5FDR, 5IEZ, 5IF4, 5JSB, 5KU9, 5LOF, 5MES, 5MEV, 5UUM, 5VKC, 5VX2, 5W89, 5W8F, 6B4L, 6B4U, 6BW2, 6BW8, 6FS0, 6FS1, 6FS2, 6MBD, 6MBE, 6NE5, 6O4U, 6O6F, 6O6G, 6OQB, 6OQC, 6OQD, 6OQN, 6OVC, 6P3P, 6QB3, 6QB4, 6QB6, 6QFC, 6QFI, 6QFM, 6QFQ, 6QGD, 6QXJ, 6QYK, 6QYL, 6QYN, 6QYO, 6QYP, 6QZ5, 6QZ6, 6QZ7, 6QZ8, 6QZB, 6STJ, 6U63, 6U64, 6U65, 6U67, 6U6F, 6UA3, 6UAB, 6UD2, 6UDI, 6UDT, 6UDU, 6UDV, 6UDX, 6UDY, 6VBX, 6YBG, 6YBJ, 6YBK, 6YBL, 6ZIE, 7NB4, 7NB7, 7XGE, 8AV9, 8EKX, 8EL0, 8EL1, 8G3S, 8G3T, 8G3U, 8G3W, 8G3X, 8G3Y, 8H7B, 8IQM, 8QSO, 8SVY, 8T6F, 8VJP
{'Adipose Tissue': 350.47304817275744, 'Adrenal Gland': 169.51244186046512, 'Bladder': 214.9771428571429, 'Blood': 417.495780409042, 'Blood Vessel': 330.1543970037453, 'Brain': 56.15663701741105, 'Breast': 273.10058823529414, 'Cervix Uteri': 182.5421052631579, 'Colon': 227.17679075738127, 'Esophagus': 254.64896193771625, 'Fallopian Tube': 440.5, 'Heart': 97.38246341463416, 'Kidney': 104.11067415730338, 'Liver': 144.41384955752213, 'Lung': 500.5269896193771, 'Muscle': 124.42875466998754, 'Nerve': 298.8604200323102, 'Ovary': 230.5691111111111, 'Pancreas': 108.16524390243902, 'Pituitary': 163.3028621908127, 'Prostate': 160.88604081632653, 'Salivary Gland': 205.08827160493829, 'Skin': 310.05712548369263, 'Small Intestine': 230.6979679144385, 'Spleen': 292.63236514522816, 'Stomach': 235.7885515320334, 'Testis': 92.07828254847648, 'Thyroid': 237.49560490045943, 'Uterus': 225.58830985915495, 'Vagina': 252.8044871794872}
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null
Component of an E-cadherin/ catenin adhesion complex composed of at least E-cadherin/CDH1, beta-catenin/CTNNB1 or gamma-catenin/JUP, and potentially alpha-catenin/CTNNA1. Forms a ternary complex composed of ADAM10, CADH1 and EPHA4,
null
null
KLRG1, SPEF1, DLGAP5, AJAP1, RAPGEF2, RAB8B, PIP5K1C, PKP2, TRPV4, CTNNB1, CAV1, DDR1, TBC1D2, CTNNA1, JUP, CTNND1, PSEN1, LIMA1, CDH1, JUP, ADAM10, CADH1 , EPHA4,
null
null
null
null
Homodimer
null
79.91949
0.474025
63.504286
0.625571
2,174
P12830
Q08050-3
null
degron_data
CDH1
MGPWSRSLSALLLLLQVSSWLCQEPEPCHPGFDAESYTFTVPRRHLERGRVLGRVNFEDCTGRQRTAYFSLDTRFKVGTDGVITVKRPLRFHNPQIHFLVYAWDSTYRKFSTKVTLNTVGHHHRPPPHQASVSGIQAELLTFPNSSPGLRRQKRDWVIPPISCPENEKGPFPKNLVQIKSNKDKEGKVFYSITGQGADTPPVGVFIIERETGWLKVTEPLDRERIATYTLFSHAVSSNGNAVEDPMEILITVTDQNDNKPEFTQEVFKGSVMEGALPGTSVMEVTATDADDDVNTYNAAIAYTILSQDPELPDKNMFTINRNTGVISVVTTGLDRESFPTYTLVVQAADLQGEGLSTTATAVITVTDTNDNPPIFNPTTYKGQVPENEANVVITTLKVTDADAPNTPAWEAVYTILNDDGGQFVVTTNPVNNDGILKTAKGLDFEAKQQYILHVAVTNVVPFEVSLTTSTATVTVDVLDVNEAPIFVPPEKRVEVSEDFGVGQEITSYTAQEPDTFMEQKITYRIWRDTANWLEINPDTGAISTRAELDREDFEHVKNSTYTALIIATDNGSPVATGTGTLLLILSDVNDNAPIPEPRTIFFCERNPKPQVINIIDADLPPNTSPFTAELTHGASANWTIQYNDPTQESIILKPKMALEVGDYKINLKLMDNQNKDQVTTLEVSVCDCEGAAGVCRKAQPVEAGLQIPAILGILGGILALLILILLLLLFLRRRAVVKEPLLPPEDDTRDNVYYYDEEGGGEEDQDFDLSQLHRGLDARPEVTRNDVAPTLMSVPRYLPRPANPDEIGNFIDENLKAADTDPTAPPYDSLLVFDYEGSGSEAASLSSLNSSESDKDQDYDYLNEWGNRFKKLADMYGGGEDD
Homo sapiens
Cell junction, adherens junction, Cell membrane, Endosome, Golgi apparatus, trans-Golgi network, Cytoplasm, Cell junction, desmosome
Tissue enhanced (parathyroid)
{'Ciliated cells': '119.1', 'Basal respiratory cells': '71.1', 'Club cells': '97.3', 'Ionocytes': '81.0', 'Mucus glandular cells': '155.0', 'Serous glandular cells': '67.8', 'Gastric mucus-secreting cells': '133.2', 'Proximal enterocytes': '140.9', 'Paneth cells': '125.1', 'Distal enterocytes': '307.5', 'Intestinal goblet cells': '173.5', 'Exocrine glandular cells': '-0.605', 'Basal prostatic cells': '68.3', 'Prostatic glandular cells': '186.7', 'Breast glandular cells': '0.773', 'Breast myoepithelial cells': '0.700', 'Glandular and luminal cells': '313.0', 'Secretory cells': '82.3', 'Basal keratinocytes': '102.5', 'Suprabasal keratinocytes': '162.6', 'Basal squamous epithelial cells': '51.0', 'Squamous epithelial cells': '106.9', 'Alveolar cells type 1': '0.437', 'Alveolar cells type 2': '0.706', 'Salivary duct cells': '95.9', 'Ductal cells': '0.541', 'Hepatocytes': '0.600', 'Cholangiocytes': '129.7', 'Proximal tubular cells': '0.042', 'Distal tubular cells': '0.0', 'Collecting duct cells': '143.9', 'Mesothelial cells': '0.799', 'Sertoli cells': '0.252', 'Granulosa cells': '12.9', 'Enteroendocrine cells': '92.4', 'Pancreatic endocrine cells': '78.1', 'Leydig cells': '0.264', 'Excitatory neurons': '0.7', 'Inhibitory neurons': '1.3', 'Cone photoreceptor cells': '0.0', 'Rod photoreceptor cells': '0.0', 'Bipolar cells': '0.2', 'Horizontal cells': '0.6', 'Astrocytes': '0.6', 'Oligodendrocyte precursor cells': '0.5', 'Oligodendrocytes': '29.9', 'Microglial cells': '0.9', 'Muller glia cells': '0.1', 'Schwann cells': '0.131', 'Spermatogonia': '0.392', 'Spermatocytes': '0.193', 'Early spermatids': '-0.217', 'Late spermatids': '-0.290', 'Oocytes': '16.9', 'Cytotrophoblasts': '119.2', 'Syncytiotrophoblasts': '45.0', 'Extravillous trophoblasts': '24.9', 'Endothelial cells': '6.1', 'Lymphatic endothelial cells': '0.4', 'Cardiomyocytes': '0.135', 'Skeletal myocytes': '0.107', 'Smooth muscle cells': '5.8', 'Adipocytes': '2.1', 'Melanocytes': '0.335', 'Fibroblasts': '6.5', 'Peritubular cells': '0.210', 'Endometrial stromal cells': '27.7', 'Ovarian stromal cells': '0.7', 'Undifferentiated cells': '101.6', 'T-cells': '2.9', 'B-cells': '4.4', 'Plasma cells': '6.1', 'Nk-cells': '0.0', 'Granulocytes': '8.4', 'Monocytes': '0.0', 'Macrophages': '6.0', 'Hofbauer cells': '4.3', 'Kupffer cells': '1.0', 'Dendritic cells': '5.9', 'Langerhans cells': '0.304', 'Erythroid cells': '0.036', 'Adipocytes (Subcutaneous)': '-0.081', 'Adipocytes (Visceral)': '-0.209', 'Breast glandular cells (progenitors)': '0.538', 'Adipocytes (Breast)': '-0.689', 'Colon enterocytes': '0.790', 'Colon enteroendocrine cells': '0.112', 'Enteric glia cells': '-0.048', 'Mitotic cells (Colon)': '0.299', 'Mitotic cells (Heart)': '0.120', 'Podocytes': '-0.118', 'Ascending Loop of Henle cells': '0.475', 'Intercalated cells': '0.212', 'Cholangiocyte': '0.090', 'NK-cells (Liver)': '-0.005', 'Respiratory ciliated cells': '-0.012', 'Mitotic cells (Lung)': '0.071', 'NK-cells (Lung)': '-0.266', 'B-cells (Lung)': '-0.296', 'Alpha cells': '0.270', 'Beta cells': '0.152', 'Prostate glandular cells': '0.764', 'Prostate basal glandular cells': '0.540', 'Urothelial cells': '0.205', 'Keratinocyte (other)': '0.510', 'Keratinocyte (granular)': '0.055', 'Hair cortex cells': '0.080', 'Inner root sheath cells': '0.131', 'Outer root sheath cells': '0.175', 'Sebaceous gland cells': '0.156', 'Eccrine sweat gland cells': '-0.207', 'Adipocytes (Skin)': '-0.244', 'Mitotic cells (Skin)': '0.442', 'Parietal cells': '0.654', 'Chief cells': '0.649', 'Gastric mucous cells': '0.781', 'Gastric enteroendocrine cells': '0.590', 'Mitotic cells (Stomach)': '0.445', 'Parafollicular cells': '0.173', 'Thyroid glandular cells': '0.865', 'Mitotic cells (Thyroid)': '-0.081', 'Adrenal cortex cells': '0.051', 'Adrenal medulla cells': '0.087', 'Mitotic cells (Adrenal gland)': '0.072', 'Minor salivary glandular cells': '0.371', 'Minor salivary gland ductal cells': '-0.142', 'Minor salivary gland basal cells': '0.582', 'Mitotic cells (Minor salivary gland)': '0.567', 'Adipocytes (Minor salivary gland)': '0.050', 'Somatotropes': '0.121', 'Lactotropes': '0.322', 'Gonadotropes': '0.330', 'Corticotropes': '0.180', 'Thyrotropes': '0.496', 'Undifferentiated cells (Pituitary gland)': '-0.108', 'Mitotic cells (Spleen)': '-0.228', 'Platelets': '-0.050', 'Erythrocytes': '-0.158', 'Hematopoietic stem cells': '-0.211', 'B-cells (Spleen)': '0.266', 'NK-cells (Spleen)': '0.309', 'Amygdala excitatory': '1.0', 'Cerebellar inhibitory': '0.9', 'Cge interneuron': '0.7', 'Deep-layer corticothalamic and 6b': '1.5', 'Deep-layer intratelencephalic': '0.7', 'Deep-layer near-projecting': '0.7', 'Eccentric medium spiny neuron': '0.6', 'Hippocampal ca1-3': '1.9', 'Hippocampal ca4': '1.2', 'Hippocampal dentate gyrus': '1.1', 'Lamp5-lhx6 and chandelier': '0.5', 'Lower rhombic lip': '0.8', 'Mammillary body': '0.6', 'Medium spiny neuron': '0.7', 'Mge interneuron': '1.7', 'Midbrain-derived inhibitory': '0.7', 'Miscellaneous': '0.9', 'Splatter': '3.8', 'Thalamic excitatory': '0.5', 'Upper rhombic lip': '0.8', 'Upper-layer intratelencephalic': '0.6', 'Astrocyte': '4.4', 'Bergmann glia': '0.2', 'Central nervous system macrophage': '0.6', 'Choroid plexus epithelial cell': '52.1', 'Committed oligodendrocyte precursor': '41.5', 'Ependymal cell': '4.8', 'Oligodendrocyte': '53.1', 'Oligodendrocyte precursor cell': '2.4', 'Endothelial cell': '0.7', 'Pericyte': '0.3', 'Vascular associated smooth muscle cell': '0.0', 'Fibroblast': '17.4', 'Leukocyte': '1.1', 'Basophil': '0.0', 'Eosinophil': '0.0', 'Neutrophil': '0.0', 'Classical monocyte': '0.0', 'Non-classical monocyte': '0.0', 'Intermediate monocyte': '0.0', 'T-reg': '2.3', 'GdT-cell': '0.0', 'MAIT T-cell': '0.0', 'Memory CD4 T-cell': '0.0', 'Naive CD4 T-cell': '0.1', 'Memory CD8 T-cell': '0.2', 'Naive CD8 T-cell': '0.3', 'Memory B-cell': '0.0', 'Naive B-cell': '0.1', 'Plasmacytoid DC': '46.6', 'Myeloid DC': '8.5', 'NK-cell': '0.1', 'Total PBMC': '0.7', 'Vd2 gdTCR': '0.0', 'Memory CD4 T-cell Th1\\/Th17': '0.1', 'Memory CD4 T-cell Th17': '0.2', 'Memory CD4 T-cell Th2': '2.9', 'Non-Vd2 gdTCR': '0.1', 'Memory CD4 T-cell Th1': '0.3', 'Memory CD4 T-cell TFH': '0.5', 'Terminal effector memory CD4 T-cell': '0.0', 'Central memory CD8 T-cell': '4.8', 'Effector memory CD8 T-cell': '0.0', 'Terminal effector memory CD8 T-cell': '0.6', 'Non-switched memory B-cell': '0.0', 'Plasmablast': '3.3', 'Switched memory B-cell': '0.0', 'Exhausted memory B-cell': '0.7', 'Progenitor cell': '2.3', 'Memory T-reg': '1.3', 'Naive CD4 T-cell activated': '0.3', 'Naive CD8 T-cell activated': '0.6', 'Naive T-reg': '0.1'}
1O6S, 2O72, 2OMT, 2OMU, 2OMV, 2OMX, 2OMY, 2OMZ, 3FF7, 3FF8, 3L6X, 3L6Y, 4ZT1, 4ZTE, 6CXY, 6OLE, 6OLF, 6OLG, 6VEL, 7STZ, 8H62
{'Adipose Tissue': 1.2125261088039867, 'Adrenal Gland': 0.1914223992248062, 'Bladder': 39.2033519047619, 'Blood': 1.340954264800861, 'Blood Vessel': 0.3121561692883895, 'Brain': 0.8550442199091597, 'Breast': 38.54918344226579, 'Cervix Uteri': 23.539115789473684, 'Colon': 43.41292142490372, 'Esophagus': 53.97513367404844, 'Fallopian Tube': 14.900277777777776, 'Heart': 0.119140469221835, 'Kidney': 25.040449438202245, 'Liver': 26.60802654867257, 'Lung': 35.447986366782004, 'Muscle': 0.1378936151930261, 'Nerve': 17.518468982229404, 'Ovary': 3.6515122222222223, 'Pancreas': 56.89676829268293, 'Pituitary': 24.68741660777385, 'Prostate': 61.279967346938776, 'Salivary Gland': 92.01685185185184, 'Skin': 79.77571720232172, 'Small Intestine': 71.7519320855615, 'Spleen': 10.061029045643156, 'Stomach': 58.07813805013927, 'Testis': 0.8144204986149585, 'Thyroid': 135.176797856049, 'Uterus': 1.442593943661972, 'Vagina': 86.52345512820513}
FOXM1
MKTSPRRPLILKRRRLPLPVQNAPSETSEEEPKRSPAQQESNQAEASKEVAESNSCKFPAGIKIINHPTMPNTQVVAIPNNANIHSIITALTAKGKESGSSGPNKFILISCGGAPTQPPGLRPQTQTSYDAKRTEVTLETLGPKPAARDVNLPRPPGALCEQKRETCADGEAAGCTINNSLSNIQWLRKMSSDGLGSRSIKQEMEEKENCHLEQRQVKVEEPSRPSASWQNSVSERPPYSYMAMIQFAINSTERKRMTLKDIYTWIEDHFPYFKHIAKPGWKNSIRHNLSLHDMFVRETSANGKVSFWTIHPSANRYLTLDQVFKPLDPGSPQLPEHLESQQKRPNPELRRNMTIKTELPLGARRKMKPLLPRVSSYLVPIQFPVNQSLVLQPSVKVPLPLAASLMSSELARHSKRVRIAPKVFGEQVVFGYMSKFFSGDLRDFGTPITSLFNFIFLCLSVLLAEEGIAPLSSAGPGKEEKLLFGEGFSPLLPVQTIKEEEIQPGEEMPHLARPIKVESPPLEEWPSPAPSFKEESSHSWEDSSQSPTPRPKKSYSGLRSPTRCVSEMLVIQHRERRERSRSRRKQHLLPPCVDEPELLFSEGPSTSRWAAELPFPADSSDPASQLSYSQEVGGPFKTPIKETLPISSTPSKSVLPRTPESWRLTPPAKVGGLDFSPVQTSQGASDPLPDPLGLMDLSTTPLQSAPPLESPQRLLSSEPLDLISVPFGNSSPSDIDVPKPGSPEPQVSGLAANRSLTEGLVLDTMNDSLSKILLDISFPGLDEDPLGPDNINWSQFIPELQ
Homo sapiens
null
Not found
{}
null
{'Adipose Tissue': 1.8794906478405315, 'Adrenal Gland': 2.2110558139534886, 'Bladder': 2.0431333333333335, 'Blood': 12.430574090419803, 'Blood Vessel': 1.2020308239700377, 'Brain': 0.7483524451173353, 'Breast': 1.8677209150326797, 'Cervix Uteri': 3.321878947368421, 'Colon': 4.375473363286265, 'Esophagus': 7.357720498269896, 'Fallopian Tube': 1.9783999999999995, 'Heart': 0.6873927874564459, 'Kidney': 1.740594382022472, 'Liver': 1.9241300884955752, 'Lung': 4.729498442906574, 'Muscle': 0.2481442303860523, 'Nerve': 1.7678321486268174, 'Ovary': 1.9992594444444445, 'Pancreas': 0.778709237804878, 'Pituitary': 1.3677240282685512, 'Prostate': 3.2848930612244898, 'Salivary Gland': 3.992593827160494, 'Skin': 19.034247927031508, 'Small Intestine': 8.00771818181818, 'Spleen': 8.543099585062242, 'Stomach': 4.267721727019499, 'Testis': 42.10467590027701, 'Thyroid': 2.986481010719755, 'Uterus': 1.4417816901408451, 'Vagina': 7.3760955128205135}
[39.93, 46.46, 52.9, 44.21, 41.4, 39.93, 35.91, 38.61, 36.44, 36.25, 34.86, 32.82, 32.01, 32.75, 31.69, 35.64, 36.35, 34.66, 33.32, 32.71, 35.01, 30.17, 37.05, 36.53, 48.19, 58.22, 64.94, 73.22, 78.33, 82.63, 85.79, 89.39, 87.89, 85.58, 83.93, 89.1, 89.27, 90.66, 87.86, 86.2, 82.97, 72.75, 73.3, 76.44, 82.38, 82.41, 79.49, 86.6, 76.32, 85.48, 88.69, 84.35, 87.75, 90.57, 88.72, 89.46, 87.48, 85.3, 81.72, 79.46, 77.26, 69.01, 67.1, 62.83, 67.71, 74.96, 82.95, 86.74, 86.35, 86.49, 84.6, 85.99, 85.64, 87.19, 89.23, 89.3, 90.62, 84.21, 85.42, 83.34, 84.28, 89.8, 89.78, 87.53, 87.64, 85.98, 81.31, 80.85, 78.74, 80.15, 70.67, 69.91, 72.91, 77.13, 83.26, 84.67, 90.36, 89.7, 92.74, 89.99, 92.55, 88.84, 87.15, 83.78, 78.78, 81.48, 78.75, 84.94, 88.04, 89.37, 92.07, 91.77, 92.31, 91.07, 90.65, 87.61, 83.41, 78.8, 63.24, 54.89, 47.42, 40.03, 40.26, 30.18, 41.24, 38.09, 36.95, 39.02, 37.83, 36.36, 36.19, 34.8, 36.01, 35.89, 38.28, 40.63, 35.0, 43.8, 39.75, 41.2, 46.04, 45.19, 52.52, 50.11, 47.93, 53.4, 47.76, 53.2, 49.3, 47.37, 43.58, 49.54, 50.87, 52.57, 59.51, 56.84, 65.39, 75.23, 74.0, 76.81, 90.54, 91.49, 92.97, 92.98, 95.31, 92.72, 91.23, 88.39, 88.32, 92.62, 91.4, 93.62, 92.76, 92.53, 92.29, 91.87, 90.97, 88.74, 88.07, 86.11, 83.95, 81.44, 79.59, 77.48, 79.78, 80.16, 86.42, 88.54, 92.25, 93.3, 94.26, 95.19, 95.68, 93.9, 93.84, 92.92, 93.85, 93.32, 92.56, 91.99, 92.7, 92.88, 92.89, 95.83, 96.17, 96.07, 95.52, 94.98, 92.79, 90.65, 91.27, 90.53, 94.14, 94.46, 94.9, 95.63, 95.08, 93.37, 94.45, 95.11, 95.72, 95.28, 94.51, 93.18, 94.25, 93.29, 94.25, 94.47, 93.42, 93.97, 93.27, 92.71, 92.77, 91.3, 91.53, 87.88, 83.61, 80.32, 81.15, 86.18, 88.03, 85.48, 86.15, 87.79, 90.46, 88.71, 91.35, 91.46, 92.34, 93.87, 93.86, 94.75, 94.22, 95.1, 93.82, 94.57, 94.14, 95.02, 94.83, 96.76, 96.84, 97.44, 96.73, 95.91, 94.96, 97.16, 97.7, 97.45, 96.21, 96.94, 96.4, 94.35, 94.87, 90.59, 92.9, 93.31, 94.42, 94.07, 95.88, 96.25, 96.53, 96.25, 96.78, 97.18, 97.25, 96.72, 96.23, 96.51, 95.56, 96.21, 92.13, 89.89, 88.17, 88.01, 90.66, 92.6, 93.67, 93.51, 93.97, 96.03, 96.71, 98.09, 97.71, 97.36, 96.44, 96.73, 97.1, 96.75, 96.36, 94.3, 93.48, 94.33, 93.19, 92.99, 92.74, 96.13, 97.23, 96.82, 97.85, 96.97, 96.86, 94.15, 95.22, 96.16, 97.91, 98.01, 97.38, 97.18, 94.71, 92.18, 91.14, 90.68, 94.56, 95.0, 95.71, 94.73, 94.15, 95.03, 95.77, 97.06, 97.24, 97.75, 97.8, 97.68, 97.86, 97.8, 97.91, 97.13, 95.49, 94.14, 92.26, 92.66, 94.13, 94.02, 95.06, 96.06, 97.14, 97.5, 97.54, 97.81, 97.85, 97.86, 97.69, 97.44, 96.39, 95.35, 94.9, 92.8, 94.05, 93.01, 93.14, 93.03, 95.17, 94.88, 96.04, 90.79, 95.33, 94.45, 96.39, 97.1, 96.17, 95.42, 95.74, 95.36, 94.04, 93.98, 92.12, 91.27, 91.54, 92.4, 93.63, 95.56, 95.55, 95.66, 96.29, 96.6, 96.34, 95.12, 94.22, 94.79, 94.01, 95.01, 93.22, 92.95, 90.69, 93.42, 94.45, 93.34, 94.58, 94.94, 95.63, 95.6, 96.44, 95.63, 96.46, 94.33, 93.1, 91.06, 84.23, 85.58, 92.16, 93.71, 96.59, 95.68, 96.6, 94.91, 95.46, 93.28, 89.69, 88.08, 90.85, 92.55, 95.6, 95.99, 96.55, 97.02, 96.23, 95.76, 93.67, 91.65, 90.32, 93.62, 93.41, 94.32, 92.7, 92.3, 91.93, 92.46, 94.57, 94.85, 96.0, 96.09, 96.27, 96.84, 95.96, 95.81, 95.06, 94.62, 93.98, 92.66, 91.7, 89.67, 84.1, 82.59, 83.13, 83.53, 83.81, 88.96, 93.13, 95.45, 96.66, 97.16, 97.09, 96.87, 96.02, 95.93, 95.17, 93.44, 93.2, 92.25, 93.27, 92.54, 93.37, 95.43, 94.78, 96.03, 90.96, 95.44, 93.52, 95.65, 95.96, 96.31, 95.28, 95.37, 94.62, 93.8, 93.72, 91.71, 92.94, 91.27, 93.27, 91.35, 92.75, 94.81, 94.09, 94.4, 93.88, 95.21, 94.58, 94.3, 92.74, 91.44, 92.03, 92.43, 87.42, 84.46, 84.87, 84.4, 87.76, 91.79, 94.06, 95.66, 96.59, 95.95, 96.1, 94.69, 94.53, 93.94, 93.58, 93.24, 93.94, 95.11, 96.44, 95.59, 96.5, 96.1, 95.47, 93.88, 93.91, 93.72, 96.01, 96.34, 95.58, 95.45, 93.62, 93.56, 92.63, 94.08, 94.31, 95.13, 92.89, 92.76, 87.68, 91.58, 92.23, 92.9, 91.24, 89.46, 91.81, 94.46, 95.44, 95.93, 95.89, 96.68, 96.5, 96.7, 95.92, 94.81, 93.36, 91.55, 87.36, 84.91, 89.06, 91.5, 92.98, 95.02, 94.86, 96.3, 95.83, 97.03, 96.42, 96.23, 95.26, 95.42, 94.89, 93.19, 93.53, 92.0, 92.67, 91.49, 91.94, 91.21, 93.18, 91.64, 91.29, 89.7, 87.98, 87.65, 88.26, 88.32, 88.15, 88.04, 84.97, 83.39, 79.4, 82.74, 84.15, 86.11, 87.6, 88.96, 89.97, 90.41, 91.91, 91.12, 91.14, 92.27, 90.78, 93.18, 91.12, 89.18, 89.62, 90.61, 89.5, 86.25, 91.18, 91.97, 91.49, 91.51, 91.21, 90.51, 88.66, 86.16, 80.5, 83.22, 81.35, 81.71, 82.94, 88.0, 90.24, 91.34, 91.29, 92.33, 89.75, 86.58, 86.96, 86.23, 88.54, 89.38, 92.12, 92.39, 91.64, 91.2, 88.8, 87.35, 84.39, 80.51, 76.77, 75.75, 81.39, 83.72, 84.19, 87.87, 87.2, 89.67, 89.42, 90.82, 90.97, 92.51, 92.36, 92.89, 92.36, 90.03, 87.96, 85.97, 88.74, 90.13, 89.45, 90.35, 88.24, 89.46, 89.84, 90.07, 88.19, 88.3, 86.85, 84.97, 83.84, 82.82, 82.21, 79.41, 76.39, 66.1, 68.22, 74.4, 68.61, 63.36, 55.15, 41.66, 41.11, 43.01, 32.33, 39.86, 36.26, 41.72, 43.23, 55.38, 58.76, 62.16, 60.16, 65.37, 71.1, 74.56, 76.38, 81.2, 84.29, 85.45, 85.57, 88.55, 86.45, 86.53, 88.31, 88.89, 86.15, 83.92, 85.2, 84.0, 78.55, 77.54, 79.14, 71.75, 66.9, 66.04, 62.08, 52.01, 41.0, 35.6, 37.99, 32.58, 39.91, 39.79, 37.8, 44.59, 49.28, 45.67, 43.32, 44.39, 42.75, 44.8, 45.61, 41.87, 40.9, 44.22, 44.93, 40.58, 34.47, 36.28, 42.64, 44.81, 36.33, 37.53, 36.55, 31.88, 33.61, 36.71, 43.22, 40.36, 45.92, 43.97, 47.37, 48.95, 46.84, 42.64, 43.69, 43.17, 45.27, 43.14, 41.56, 39.85, 44.48, 49.34, 48.03, 44.76, 46.26, 45.11, 52.26, 47.51, 49.58, 50.31, 52.17, 53.06, 54.47, 55.5, 57.89, 57.56, 59.79, 65.12, 66.93, 68.41, 70.79, 67.57, 68.53, 69.64, 67.58, 66.04, 66.79, 65.01, 69.78, 73.95, 76.55, 76.71, 72.44, 76.54, 75.85, 74.76, 74.72, 76.36, 75.07, 67.72, 67.37, 69.16, 70.0, 61.64, 63.7, 57.89, 54.12, 47.37, 44.62, 41.93, 41.5, 42.58, 44.57, 44.28, 39.27, 41.11, 39.96, 41.73, 41.86, 35.69, 45.09, 38.03, 44.0, 44.36, 42.28, 41.43, 39.83, 40.51, 40.5, 35.5, 43.19, 34.98, 38.91, 47.07, 47.66, 45.04, 52.1, 53.63, 54.74, 60.8, 66.6, 67.38, 73.78, 70.69, 71.39, 73.71, 71.26, 75.83, 77.11, 78.67, 73.71, 72.61, 73.27, 70.36, 72.63, 72.69, 68.11, 66.06, 60.67, 52.64, 44.07, 48.46, 43.79, 36.31]
[1.0, 1.0, 1.0, 1.0, 0.98, 1.0, 0.91, 0.96, 0.9, 0.88, 1.0, 1.0, 1.0, 1.0, 1.0, 0.87, 0.99, 0.76, 0.96, 1.0, 0.98, 0.95, 0.93, 0.92, 0.87, 0.92, 0.69, 0.71, 0.79, 0.3, 0.2, 0.17, 0.63, 0.32, 0.89, 0.66, 0.1, 0.62, 0.15, 0.67, 0.03, 0.67, 0.77, 0.54, 0.57, 0.04, 0.68, 0.73, 0.54, 0.54, 0.59, 0.08, 0.19, 0.61, 0.0, 0.39, 0.06, 0.63, 0.14, 0.63, 0.49, 0.83, 0.72, 0.93, 0.78, 0.07, 0.63, 0.12, 0.52, 0.15, 0.6, 0.19, 0.51, 0.41, 0.03, 0.62, 0.11, 0.3, 0.46, 0.47, 0.0, 0.23, 0.0, 0.24, 0.03, 0.5, 0.67, 0.61, 0.06, 0.78, 0.04, 0.83, 0.7, 0.57, 0.54, 0.13, 0.52, 0.06, 0.45, 0.0, 0.11, 0.0, 0.38, 0.12, 0.54, 0.79, 0.81, 0.65, 0.6, 0.24, 0.6, 0.01, 0.47, 0.01, 0.12, 0.0, 0.25, 0.26, 0.46, 0.93, 0.85, 0.99, 0.94, 1.0, 0.91, 0.99, 0.99, 0.98, 1.0, 1.0, 1.0, 1.0, 0.99, 0.98, 0.98, 0.92, 0.93, 0.87, 0.82, 0.85, 0.76, 0.9, 0.91, 0.9, 0.93, 0.65, 0.96, 0.84, 0.86, 0.96, 0.99, 0.96, 0.7, 0.92, 0.89, 0.8, 0.83, 0.23, 0.86, 0.73, 0.12, 0.62, 0.06, 0.4, 0.02, 0.42, 0.35, 0.9, 0.64, 0.82, 0.29, 0.51, 0.17, 0.54, 0.27, 0.29, 0.51, 0.08, 0.77, 0.06, 0.62, 0.39, 0.34, 0.94, 0.83, 0.46, 0.51, 0.07, 0.17, 0.07, 0.41, 0.14, 0.31, 0.2, 0.36, 0.0, 0.13, 0.59, 0.53, 0.77, 0.2, 0.64, 0.35, 0.0, 0.02, 0.39, 0.18, 0.39, 0.57, 0.63, 0.39, 0.0, 0.32, 0.0, 0.18, 0.03, 0.29, 0.47, 0.55, 0.03, 0.34, 0.2, 0.45, 0.56, 0.17, 0.37, 0.59, 0.01, 0.39, 0.0, 0.39, 0.05, 0.28, 0.07, 0.29, 0.26, 0.64, 0.82, 0.64, 0.63, 0.76, 0.15, 0.39, 0.95, 0.57, 0.28, 0.58, 0.02, 0.43, 0.0, 0.29, 0.09, 0.4, 0.13, 0.49, 0.31, 0.53, 0.32, 0.66, 0.01, 0.71, 0.13, 0.56, 0.54, 0.84, 0.51, 0.06, 0.82, 0.14, 0.54, 0.07, 0.63, 0.05, 0.7, 0.17, 0.75, 0.51, 0.64, 0.36, 0.67, 0.15, 0.12, 0.61, 0.0, 0.33, 0.14, 0.62, 0.2, 0.52, 0.05, 0.14, 0.63, 0.95, 0.85, 0.32, 0.6, 0.1, 0.12, 0.17, 0.17, 0.06, 0.08, 0.41, 0.28, 0.55, 0.49, 0.09, 0.68, 0.23, 0.53, 0.64, 0.52, 0.42, 0.64, 0.64, 0.0, 0.08, 0.44, 0.13, 0.48, 0.52, 0.81, 0.44, 0.0, 0.26, 0.0, 0.21, 0.03, 0.46, 0.27, 0.71, 0.45, 0.06, 0.28, 0.28, 0.4, 0.65, 0.28, 0.46, 0.61, 0.0, 0.36, 0.0, 0.32, 0.01, 0.22, 0.0, 0.05, 0.0, 0.41, 0.46, 0.42, 0.82, 0.48, 0.4, 0.5, 0.17, 0.62, 0.06, 0.32, 0.0, 0.25, 0.0, 0.42, 0.08, 0.41, 0.27, 0.16, 0.04, 0.36, 0.32, 0.2, 0.0, 0.52, 0.04, 0.66, 0.47, 0.52, 0.78, 0.09, 0.77, 0.08, 0.6, 0.0, 0.31, 0.03, 0.58, 0.47, 0.59, 0.44, 0.23, 0.54, 0.1, 0.18, 0.45, 0.0, 0.53, 0.11, 0.59, 0.17, 0.51, 0.01, 0.19, 0.71, 0.77, 0.3, 0.44, 0.08, 0.14, 0.52, 0.05, 0.37, 0.1, 0.42, 0.23, 0.61, 0.43, 0.22, 0.96, 0.54, 0.4, 0.3, 0.07, 0.39, 0.17, 0.43, 0.38, 0.3, 0.8, 0.83, 0.44, 0.03, 0.11, 0.0, 0.23, 0.0, 0.31, 0.0, 0.38, 0.58, 0.51, 0.01, 0.49, 0.13, 0.26, 0.69, 0.46, 0.41, 0.51, 0.06, 0.51, 0.03, 0.38, 0.0, 0.06, 0.0, 0.34, 0.08, 0.53, 0.42, 0.88, 0.25, 0.75, 0.49, 1.0, 0.34, 0.86, 0.48, 0.18, 0.52, 0.01, 0.32, 0.0, 0.19, 0.0, 0.3, 0.05, 0.44, 0.27, 0.43, 0.11, 0.31, 0.39, 0.03, 0.55, 0.04, 0.52, 0.51, 0.64, 0.57, 0.19, 0.68, 0.13, 0.84, 0.06, 0.31, 0.07, 0.69, 0.26, 0.37, 0.53, 0.67, 0.5, 0.56, 0.14, 0.18, 0.47, 0.01, 0.47, 0.15, 0.61, 0.28, 0.2, 0.02, 0.76, 0.55, 0.31, 0.94, 0.22, 0.57, 0.17, 0.4, 0.07, 0.5, 0.31, 0.7, 0.2, 0.14, 0.3, 0.23, 0.58, 0.07, 0.06, 0.55, 0.15, 0.46, 0.43, 0.64, 0.53, 0.0, 0.18, 0.01, 0.23, 0.02, 0.63, 0.33, 0.79, 0.06, 0.38, 0.07, 0.14, 0.23, 0.68, 0.89, 0.29, 0.06, 0.72, 0.92, 0.24, 0.25, 0.0, 0.46, 0.02, 0.21, 0.01, 0.06, 0.0, 0.05, 0.07, 0.61, 0.17, 0.89, 0.72, 0.66, 0.14, 0.52, 0.07, 0.58, 0.01, 0.26, 0.0, 0.13, 0.0, 0.29, 0.04, 0.46, 0.27, 0.28, 0.23, 0.56, 0.32, 0.25, 0.0, 0.33, 0.05, 0.55, 0.5, 0.58, 0.53, 0.04, 0.27, 0.02, 0.04, 0.37, 0.67, 0.74, 0.35, 0.62, 0.54, 0.26, 0.46, 0.0, 0.47, 0.09, 0.45, 0.15, 0.39, 0.05, 0.44, 0.85, 0.56, 0.11, 0.11, 0.35, 0.42, 0.03, 0.32, 0.12, 0.49, 0.19, 0.25, 0.8, 0.6, 0.09, 0.49, 0.57, 0.36, 0.04, 0.35, 0.28, 0.52, 0.39, 0.5, 0.28, 0.93, 0.47, 0.3, 0.47, 0.08, 0.02, 0.18, 0.01, 0.34, 0.23, 0.55, 0.57, 0.91, 0.1, 0.78, 0.52, 0.34, 0.61, 0.24, 0.75, 0.0, 0.2, 0.02, 0.24, 0.0, 0.18, 0.04, 0.44, 0.59, 0.71, 0.29, 0.52, 0.37, 0.5, 0.11, 0.6, 0.02, 0.48, 0.01, 0.16, 0.04, 0.35, 0.66, 0.47, 0.74, 0.14, 0.62, 0.16, 0.77, 0.79, 0.27, 0.93, 0.69, 0.88, 0.88, 0.85, 0.87, 0.91, 0.92, 0.82, 0.63, 0.75, 0.7, 0.7, 0.38, 0.43, 0.64, 0.55, 0.54, 0.59, 0.45, 0.47, 0.5, 0.58, 0.52, 0.61, 0.57, 0.52, 0.68, 0.44, 0.6, 0.61, 0.58, 0.55, 0.5, 0.61, 0.61, 0.86, 0.86, 0.75, 0.91, 0.96, 0.93, 1.0, 0.87, 0.97, 0.91, 0.95, 0.86, 0.98, 0.93, 0.88, 0.59, 0.87, 0.7, 0.67, 0.85, 0.89, 0.88, 0.91, 0.93, 0.88, 0.99, 0.92, 1.0, 0.79, 0.9, 1.0, 0.94, 1.0, 0.97, 0.96, 0.9, 0.63, 0.68, 0.48, 0.54, 0.8, 0.7, 0.7, 0.95, 0.87, 0.77, 0.84, 0.79, 0.89, 0.95, 0.8, 0.77, 0.51, 0.87, 0.7, 0.52, 0.84, 0.91, 0.51, 0.96, 0.79, 0.92, 0.84, 0.21, 0.89, 0.53, 0.52, 0.89, 0.86, 0.26, 0.91, 0.45, 0.68, 0.84, 0.48, 0.44, 0.51, 0.62, 0.28, 0.59, 0.63, 0.57, 0.15, 0.55, 0.66, 0.1, 0.38, 0.74, 0.65, 0.17, 0.43, 0.66, 0.41, 0.8, 0.75, 0.9, 0.93, 0.52, 0.76, 0.89, 0.87, 0.76, 0.92, 0.91, 0.75, 0.61, 0.96, 0.89, 0.73, 0.97, 0.68, 0.87, 0.55, 0.85, 0.77, 0.69, 0.76, 0.98, 0.83, 0.68, 0.82, 0.74, 0.65, 0.96, 0.93, 0.54, 0.64, 0.28, 0.54, 0.52, 0.16, 0.51, 0.88, 0.6, 0.4, 0.88, 0.95, 0.33, 0.56, 0.73, 0.39, 0.06, 0.61, 0.75, 0.47, 0.19, 0.87, 0.7, 0.97, 0.94, 0.97]
null
null
null
Component of an E-cadherin/ catenin adhesion complex composed of at least E-cadherin/CDH1, beta-catenin/CTNNB1 or gamma-catenin/JUP, and potentially alpha-catenin/CTNNA1. Forms a ternary complex composed of ADAM10, CADH1 and EPHA4,
null
null
KLRG1, SPEF1, DLGAP5, AJAP1, RAPGEF2, RAB8B, PIP5K1C, PKP2, TRPV4, CTNNB1, CAV1, DDR1, TBC1D2, CTNNA1, JUP, CTNND1, PSEN1, LIMA1, CDH1, JUP, ADAM10, CADH1 , EPHA4,
null
null
null
null
Homodimer
null
79.91949
0.474025
null
null
799
P12830
Q12834
null
degron_data
CDH1
MGPWSRSLSALLLLLQVSSWLCQEPEPCHPGFDAESYTFTVPRRHLERGRVLGRVNFEDCTGRQRTAYFSLDTRFKVGTDGVITVKRPLRFHNPQIHFLVYAWDSTYRKFSTKVTLNTVGHHHRPPPHQASVSGIQAELLTFPNSSPGLRRQKRDWVIPPISCPENEKGPFPKNLVQIKSNKDKEGKVFYSITGQGADTPPVGVFIIERETGWLKVTEPLDRERIATYTLFSHAVSSNGNAVEDPMEILITVTDQNDNKPEFTQEVFKGSVMEGALPGTSVMEVTATDADDDVNTYNAAIAYTILSQDPELPDKNMFTINRNTGVISVVTTGLDRESFPTYTLVVQAADLQGEGLSTTATAVITVTDTNDNPPIFNPTTYKGQVPENEANVVITTLKVTDADAPNTPAWEAVYTILNDDGGQFVVTTNPVNNDGILKTAKGLDFEAKQQYILHVAVTNVVPFEVSLTTSTATVTVDVLDVNEAPIFVPPEKRVEVSEDFGVGQEITSYTAQEPDTFMEQKITYRIWRDTANWLEINPDTGAISTRAELDREDFEHVKNSTYTALIIATDNGSPVATGTGTLLLILSDVNDNAPIPEPRTIFFCERNPKPQVINIIDADLPPNTSPFTAELTHGASANWTIQYNDPTQESIILKPKMALEVGDYKINLKLMDNQNKDQVTTLEVSVCDCEGAAGVCRKAQPVEAGLQIPAILGILGGILALLILILLLLLFLRRRAVVKEPLLPPEDDTRDNVYYYDEEGGGEEDQDFDLSQLHRGLDARPEVTRNDVAPTLMSVPRYLPRPANPDEIGNFIDENLKAADTDPTAPPYDSLLVFDYEGSGSEAASLSSLNSSESDKDQDYDYLNEWGNRFKKLADMYGGGEDD
Homo sapiens
Cell junction, adherens junction, Cell membrane, Endosome, Golgi apparatus, trans-Golgi network, Cytoplasm, Cell junction, desmosome
Tissue enhanced (parathyroid)
{'Ciliated cells': '119.1', 'Basal respiratory cells': '71.1', 'Club cells': '97.3', 'Ionocytes': '81.0', 'Mucus glandular cells': '155.0', 'Serous glandular cells': '67.8', 'Gastric mucus-secreting cells': '133.2', 'Proximal enterocytes': '140.9', 'Paneth cells': '125.1', 'Distal enterocytes': '307.5', 'Intestinal goblet cells': '173.5', 'Exocrine glandular cells': '-0.605', 'Basal prostatic cells': '68.3', 'Prostatic glandular cells': '186.7', 'Breast glandular cells': '0.773', 'Breast myoepithelial cells': '0.700', 'Glandular and luminal cells': '313.0', 'Secretory cells': '82.3', 'Basal keratinocytes': '102.5', 'Suprabasal keratinocytes': '162.6', 'Basal squamous epithelial cells': '51.0', 'Squamous epithelial cells': '106.9', 'Alveolar cells type 1': '0.437', 'Alveolar cells type 2': '0.706', 'Salivary duct cells': '95.9', 'Ductal cells': '0.541', 'Hepatocytes': '0.600', 'Cholangiocytes': '129.7', 'Proximal tubular cells': '0.042', 'Distal tubular cells': '0.0', 'Collecting duct cells': '143.9', 'Mesothelial cells': '0.799', 'Sertoli cells': '0.252', 'Granulosa cells': '12.9', 'Enteroendocrine cells': '92.4', 'Pancreatic endocrine cells': '78.1', 'Leydig cells': '0.264', 'Excitatory neurons': '0.7', 'Inhibitory neurons': '1.3', 'Cone photoreceptor cells': '0.0', 'Rod photoreceptor cells': '0.0', 'Bipolar cells': '0.2', 'Horizontal cells': '0.6', 'Astrocytes': '0.6', 'Oligodendrocyte precursor cells': '0.5', 'Oligodendrocytes': '29.9', 'Microglial cells': '0.9', 'Muller glia cells': '0.1', 'Schwann cells': '0.131', 'Spermatogonia': '0.392', 'Spermatocytes': '0.193', 'Early spermatids': '-0.217', 'Late spermatids': '-0.290', 'Oocytes': '16.9', 'Cytotrophoblasts': '119.2', 'Syncytiotrophoblasts': '45.0', 'Extravillous trophoblasts': '24.9', 'Endothelial cells': '6.1', 'Lymphatic endothelial cells': '0.4', 'Cardiomyocytes': '0.135', 'Skeletal myocytes': '0.107', 'Smooth muscle cells': '5.8', 'Adipocytes': '2.1', 'Melanocytes': '0.335', 'Fibroblasts': '6.5', 'Peritubular cells': '0.210', 'Endometrial stromal cells': '27.7', 'Ovarian stromal cells': '0.7', 'Undifferentiated cells': '101.6', 'T-cells': '2.9', 'B-cells': '4.4', 'Plasma cells': '6.1', 'Nk-cells': '0.0', 'Granulocytes': '8.4', 'Monocytes': '0.0', 'Macrophages': '6.0', 'Hofbauer cells': '4.3', 'Kupffer cells': '1.0', 'Dendritic cells': '5.9', 'Langerhans cells': '0.304', 'Erythroid cells': '0.036', 'Adipocytes (Subcutaneous)': '-0.081', 'Adipocytes (Visceral)': '-0.209', 'Breast glandular cells (progenitors)': '0.538', 'Adipocytes (Breast)': '-0.689', 'Colon enterocytes': '0.790', 'Colon enteroendocrine cells': '0.112', 'Enteric glia cells': '-0.048', 'Mitotic cells (Colon)': '0.299', 'Mitotic cells (Heart)': '0.120', 'Podocytes': '-0.118', 'Ascending Loop of Henle cells': '0.475', 'Intercalated cells': '0.212', 'Cholangiocyte': '0.090', 'NK-cells (Liver)': '-0.005', 'Respiratory ciliated cells': '-0.012', 'Mitotic cells (Lung)': '0.071', 'NK-cells (Lung)': '-0.266', 'B-cells (Lung)': '-0.296', 'Alpha cells': '0.270', 'Beta cells': '0.152', 'Prostate glandular cells': '0.764', 'Prostate basal glandular cells': '0.540', 'Urothelial cells': '0.205', 'Keratinocyte (other)': '0.510', 'Keratinocyte (granular)': '0.055', 'Hair cortex cells': '0.080', 'Inner root sheath cells': '0.131', 'Outer root sheath cells': '0.175', 'Sebaceous gland cells': '0.156', 'Eccrine sweat gland cells': '-0.207', 'Adipocytes (Skin)': '-0.244', 'Mitotic cells (Skin)': '0.442', 'Parietal cells': '0.654', 'Chief cells': '0.649', 'Gastric mucous cells': '0.781', 'Gastric enteroendocrine cells': '0.590', 'Mitotic cells (Stomach)': '0.445', 'Parafollicular cells': '0.173', 'Thyroid glandular cells': '0.865', 'Mitotic cells (Thyroid)': '-0.081', 'Adrenal cortex cells': '0.051', 'Adrenal medulla cells': '0.087', 'Mitotic cells (Adrenal gland)': '0.072', 'Minor salivary glandular cells': '0.371', 'Minor salivary gland ductal cells': '-0.142', 'Minor salivary gland basal cells': '0.582', 'Mitotic cells (Minor salivary gland)': '0.567', 'Adipocytes (Minor salivary gland)': '0.050', 'Somatotropes': '0.121', 'Lactotropes': '0.322', 'Gonadotropes': '0.330', 'Corticotropes': '0.180', 'Thyrotropes': '0.496', 'Undifferentiated cells (Pituitary gland)': '-0.108', 'Mitotic cells (Spleen)': '-0.228', 'Platelets': '-0.050', 'Erythrocytes': '-0.158', 'Hematopoietic stem cells': '-0.211', 'B-cells (Spleen)': '0.266', 'NK-cells (Spleen)': '0.309', 'Amygdala excitatory': '1.0', 'Cerebellar inhibitory': '0.9', 'Cge interneuron': '0.7', 'Deep-layer corticothalamic and 6b': '1.5', 'Deep-layer intratelencephalic': '0.7', 'Deep-layer near-projecting': '0.7', 'Eccentric medium spiny neuron': '0.6', 'Hippocampal ca1-3': '1.9', 'Hippocampal ca4': '1.2', 'Hippocampal dentate gyrus': '1.1', 'Lamp5-lhx6 and chandelier': '0.5', 'Lower rhombic lip': '0.8', 'Mammillary body': '0.6', 'Medium spiny neuron': '0.7', 'Mge interneuron': '1.7', 'Midbrain-derived inhibitory': '0.7', 'Miscellaneous': '0.9', 'Splatter': '3.8', 'Thalamic excitatory': '0.5', 'Upper rhombic lip': '0.8', 'Upper-layer intratelencephalic': '0.6', 'Astrocyte': '4.4', 'Bergmann glia': '0.2', 'Central nervous system macrophage': '0.6', 'Choroid plexus epithelial cell': '52.1', 'Committed oligodendrocyte precursor': '41.5', 'Ependymal cell': '4.8', 'Oligodendrocyte': '53.1', 'Oligodendrocyte precursor cell': '2.4', 'Endothelial cell': '0.7', 'Pericyte': '0.3', 'Vascular associated smooth muscle cell': '0.0', 'Fibroblast': '17.4', 'Leukocyte': '1.1', 'Basophil': '0.0', 'Eosinophil': '0.0', 'Neutrophil': '0.0', 'Classical monocyte': '0.0', 'Non-classical monocyte': '0.0', 'Intermediate monocyte': '0.0', 'T-reg': '2.3', 'GdT-cell': '0.0', 'MAIT T-cell': '0.0', 'Memory CD4 T-cell': '0.0', 'Naive CD4 T-cell': '0.1', 'Memory CD8 T-cell': '0.2', 'Naive CD8 T-cell': '0.3', 'Memory B-cell': '0.0', 'Naive B-cell': '0.1', 'Plasmacytoid DC': '46.6', 'Myeloid DC': '8.5', 'NK-cell': '0.1', 'Total PBMC': '0.7', 'Vd2 gdTCR': '0.0', 'Memory CD4 T-cell Th1\\/Th17': '0.1', 'Memory CD4 T-cell Th17': '0.2', 'Memory CD4 T-cell Th2': '2.9', 'Non-Vd2 gdTCR': '0.1', 'Memory CD4 T-cell Th1': '0.3', 'Memory CD4 T-cell TFH': '0.5', 'Terminal effector memory CD4 T-cell': '0.0', 'Central memory CD8 T-cell': '4.8', 'Effector memory CD8 T-cell': '0.0', 'Terminal effector memory CD8 T-cell': '0.6', 'Non-switched memory B-cell': '0.0', 'Plasmablast': '3.3', 'Switched memory B-cell': '0.0', 'Exhausted memory B-cell': '0.7', 'Progenitor cell': '2.3', 'Memory T-reg': '1.3', 'Naive CD4 T-cell activated': '0.3', 'Naive CD8 T-cell activated': '0.6', 'Naive T-reg': '0.1'}
1O6S, 2O72, 2OMT, 2OMU, 2OMV, 2OMX, 2OMY, 2OMZ, 3FF7, 3FF8, 3L6X, 3L6Y, 4ZT1, 4ZTE, 6CXY, 6OLE, 6OLF, 6OLG, 6VEL, 7STZ, 8H62
{'Adipose Tissue': 1.2125261088039867, 'Adrenal Gland': 0.1914223992248062, 'Bladder': 39.2033519047619, 'Blood': 1.340954264800861, 'Blood Vessel': 0.3121561692883895, 'Brain': 0.8550442199091597, 'Breast': 38.54918344226579, 'Cervix Uteri': 23.539115789473684, 'Colon': 43.41292142490372, 'Esophagus': 53.97513367404844, 'Fallopian Tube': 14.900277777777776, 'Heart': 0.119140469221835, 'Kidney': 25.040449438202245, 'Liver': 26.60802654867257, 'Lung': 35.447986366782004, 'Muscle': 0.1378936151930261, 'Nerve': 17.518468982229404, 'Ovary': 3.6515122222222223, 'Pancreas': 56.89676829268293, 'Pituitary': 24.68741660777385, 'Prostate': 61.279967346938776, 'Salivary Gland': 92.01685185185184, 'Skin': 79.77571720232172, 'Small Intestine': 71.7519320855615, 'Spleen': 10.061029045643156, 'Stomach': 58.07813805013927, 'Testis': 0.8144204986149585, 'Thyroid': 135.176797856049, 'Uterus': 1.442593943661972, 'Vagina': 86.52345512820513}
CDC20
MAQFAFESDLHSLLQLDAPIPNAPPARWQRKAKEAAGPAPSPMRAANRSHSAGRTPGRTPGKSSSKVQTTPSKPGGDRYIPHRSAAQMEVASFLLSKENQPENSQTPTKKEHQKAWALNLNGFDVEEAKILRLSGKPQNAPEGYQNRLKVLYSQKATPGSSRKTCRYIPSLPDRILDAPEIRNDYYLNLVDWSSGNVLAVALDNSVYLWSASSGDILQLLQMEQPGEYISSVAWIKEGNYLAVGTSSAEVQLWDVQQQKRLRNMTSHSARVGSLSWNSYILSSGSRSGHIHHHDVRVAEHHVATLSGHSQEVCGLRWAPDGRHLASGGNDNLVNVWPSAPGEGGWVPLQTFTQHQGAVKAVAWCPWQSNVLATGGGTSDRHIRIWNVCSGACLSAVDAHSQVCSILWSPHYKELISGHGFAQNQLVIWKYPTMAKVAELKGHTSRVLSLTMSPDGATVASAAADETLRLWRCFELDPARRREREKASAAKSSLIHQGIR
Homo sapiens
Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, Chromosome, centromere, kinetochore, Cytoplasm, cytoskeleton, spindle pole
Tissue enhanced (bone marrow, lymphoid tissue, testis)
{'Ciliated cells': '10.7', 'Basal respiratory cells': '18.1', 'Club cells': '5.1', 'Ionocytes': '13.6', 'Mucus glandular cells': '3.0', 'Serous glandular cells': '7.7', 'Gastric mucus-secreting cells': '13.0', 'Proximal enterocytes': '2.5', 'Paneth cells': '1.5', 'Distal enterocytes': '3.3', 'Intestinal goblet cells': '13.7', 'Exocrine glandular cells': '-0.309', 'Basal prostatic cells': '0.5', 'Prostatic glandular cells': '0.0', 'Breast glandular cells': '0.389', 'Breast myoepithelial cells': '0.180', 'Glandular and luminal cells': '4.8', 'Secretory cells': '0.8', 'Basal keratinocytes': '23.5', 'Suprabasal keratinocytes': '12.1', 'Basal squamous epithelial cells': '16.6', 'Squamous epithelial cells': '45.2', 'Alveolar cells type 1': '-0.269', 'Alveolar cells type 2': '0.212', 'Salivary duct cells': '5.7', 'Ductal cells': '0.460', 'Hepatocytes': '0.320', 'Cholangiocytes': '1.9', 'Proximal tubular cells': '0.491', 'Distal tubular cells': '3.1', 'Collecting duct cells': '0.0', 'Mesothelial cells': '-0.109', 'Sertoli cells': '-0.447', 'Granulosa cells': '6.6', 'Enteroendocrine cells': '5.1', 'Pancreatic endocrine cells': '30.6', 'Leydig cells': '-0.493', 'Excitatory neurons': '0.1', 'Inhibitory neurons': '0.0', 'Cone photoreceptor cells': '0.0', 'Rod photoreceptor cells': '2.8', 'Bipolar cells': '0.4', 'Horizontal cells': '0.0', 'Astrocytes': '0.0', 'Oligodendrocyte precursor cells': '0.0', 'Oligodendrocytes': '1.5', 'Microglial cells': '0.0', 'Muller glia cells': '0.0', 'Schwann cells': '0.072', 'Spermatogonia': '-0.113', 'Spermatocytes': '0.279', 'Early spermatids': '0.741', 'Late spermatids': '0.592', 'Oocytes': '12.5', 'Cytotrophoblasts': '73.3', 'Syncytiotrophoblasts': '11.3', 'Extravillous trophoblasts': '148.6', 'Endothelial cells': '3.3', 'Lymphatic endothelial cells': '0.3', 'Cardiomyocytes': '0.471', 'Skeletal myocytes': '-0.141', 'Smooth muscle cells': '3.1', 'Adipocytes': '2.0', 'Melanocytes': '0.465', 'Fibroblasts': '9.2', 'Peritubular cells': '-0.419', 'Endometrial stromal cells': '1.7', 'Ovarian stromal cells': '0.4', 'Undifferentiated cells': '76.0', 'T-cells': '4.6', 'B-cells': '1.6', 'Plasma cells': '49.4', 'Nk-cells': '1.2', 'Granulocytes': '2.0', 'Monocytes': '0.2', 'Macrophages': '7.0', 'Hofbauer cells': '29.9', 'Kupffer cells': '5.8', 'Dendritic cells': '0.4', 'Langerhans cells': '0.175', 'Erythroid cells': '0.139', 'Adipocytes (Subcutaneous)': '0.228', 'Adipocytes (Visceral)': '0.094', 'Breast glandular cells (progenitors)': '0.372', 'Adipocytes (Breast)': '-0.147', 'Colon enterocytes': '0.377', 'Colon enteroendocrine cells': '-0.181', 'Enteric glia cells': '-0.260', 'Mitotic cells (Colon)': '0.682', 'Mitotic cells (Heart)': '0.755', 'Podocytes': '-0.128', 'Ascending Loop of Henle cells': '0.116', 'Intercalated cells': '-0.141', 'Cholangiocyte': '0.317', 'NK-cells (Liver)': '-0.127', 'Respiratory ciliated cells': '0.052', 'Mitotic cells (Lung)': '0.870', 'NK-cells (Lung)': '-0.178', 'B-cells (Lung)': '-0.028', 'Alpha cells': '0.195', 'Beta cells': '0.079', 'Prostate glandular cells': '-0.077', 'Prostate basal glandular cells': '0.267', 'Urothelial cells': '0.231', 'Keratinocyte (other)': '0.296', 'Keratinocyte (granular)': '-0.055', 'Hair cortex cells': '0.020', 'Inner root sheath cells': '0.146', 'Outer root sheath cells': '0.145', 'Sebaceous gland cells': '0.172', 'Eccrine sweat gland cells': '-0.109', 'Adipocytes (Skin)': '-0.136', 'Mitotic cells (Skin)': '0.843', 'Parietal cells': '0.201', 'Chief cells': '0.163', 'Gastric mucous cells': '0.628', 'Gastric enteroendocrine cells': '0.253', 'Mitotic cells (Stomach)': '0.912', 'Parafollicular cells': '0.005', 'Thyroid glandular cells': '0.284', 'Mitotic cells (Thyroid)': '0.288', 'Adrenal cortex cells': '0.390', 'Adrenal medulla cells': '0.126', 'Mitotic cells (Adrenal gland)': '0.899', 'Minor salivary glandular cells': '0.070', 'Minor salivary gland ductal cells': '-0.179', 'Minor salivary gland basal cells': '0.716', 'Mitotic cells (Minor salivary gland)': '0.866', 'Adipocytes (Minor salivary gland)': '0.224', 'Somatotropes': '-0.263', 'Lactotropes': '-0.135', 'Gonadotropes': '0.036', 'Corticotropes': '-0.079', 'Thyrotropes': '-0.010', 'Undifferentiated cells (Pituitary gland)': '0.345', 'Mitotic cells (Spleen)': '0.905', 'Platelets': '0.216', 'Erythrocytes': '0.290', 'Hematopoietic stem cells': '0.378', 'B-cells (Spleen)': '-0.103', 'NK-cells (Spleen)': '-0.290', 'Amygdala excitatory': '0.1', 'Cerebellar inhibitory': '0.1', 'Cge interneuron': '0.1', 'Deep-layer corticothalamic and 6b': '0.1', 'Deep-layer intratelencephalic': '0.1', 'Deep-layer near-projecting': '0.0', 'Eccentric medium spiny neuron': '0.0', 'Hippocampal ca1-3': '0.1', 'Hippocampal ca4': '0.1', 'Hippocampal dentate gyrus': '0.1', 'Lamp5-lhx6 and chandelier': '0.1', 'Lower rhombic lip': '0.1', 'Mammillary body': '0.1', 'Medium spiny neuron': '0.1', 'Mge interneuron': '0.2', 'Midbrain-derived inhibitory': '0.1', 'Miscellaneous': '0.1', 'Splatter': '0.1', 'Thalamic excitatory': '0.0', 'Upper rhombic lip': '0.3', 'Upper-layer intratelencephalic': '0.2', 'Astrocyte': '0.1', 'Bergmann glia': '0.0', 'Central nervous system macrophage': '0.2', 'Choroid plexus epithelial cell': '0.7', 'Committed oligodendrocyte precursor': '0.6', 'Ependymal cell': '0.2', 'Oligodendrocyte': '2.7', 'Oligodendrocyte precursor cell': '0.1', 'Endothelial cell': '0.1', 'Pericyte': '0.2', 'Vascular associated smooth muscle cell': '0.0', 'Fibroblast': '0.1', 'Leukocyte': '0.1', 'Basophil': '0.1', 'Eosinophil': '0.0', 'Neutrophil': '0.0', 'Classical monocyte': '0.5', 'Non-classical monocyte': '0.4', 'Intermediate monocyte': '0.3', 'T-reg': '8.6', 'GdT-cell': '0.3', 'MAIT T-cell': '0.0', 'Memory CD4 T-cell': '3.2', 'Naive CD4 T-cell': '0.9', 'Memory CD8 T-cell': '3.5', 'Naive CD8 T-cell': '1.5', 'Memory B-cell': '4.2', 'Naive B-cell': '0.4', 'Plasmacytoid DC': '1.0', 'Myeloid DC': '1.9', 'NK-cell': '1.7', 'Total PBMC': '7.3', 'Vd2 gdTCR': '0.7', 'Memory CD4 T-cell Th1\\/Th17': '1.0', 'Memory CD4 T-cell Th17': '1.1', 'Memory CD4 T-cell Th2': '1.4', 'Non-Vd2 gdTCR': '0.0', 'Memory CD4 T-cell Th1': '2.1', 'Memory CD4 T-cell TFH': '0.6', 'Terminal effector memory CD4 T-cell': '0.0', 'Central memory CD8 T-cell': '2.4', 'Effector memory CD8 T-cell': '11.2', 'Terminal effector memory CD8 T-cell': '1.0', 'Non-switched memory B-cell': '1.7', 'Plasmablast': '122.6', 'Switched memory B-cell': '6.5', 'Exhausted memory B-cell': '14.6', 'Progenitor cell': '1.7', 'Memory T-reg': '5.5', 'Naive CD4 T-cell activated': '0.6', 'Naive CD8 T-cell activated': '1.0', 'Naive T-reg': '0.8'}
4GGA, 4GGC, 4GGD, 4N14, 5G04, 5KHR, 5KHU, 5LCW, 6F0X, 6Q6G, 6Q6H
{'Adipose Tissue': 2.2786306644518275, 'Adrenal Gland': 2.048905968992248, 'Bladder': 1.9396333333333335, 'Blood': 29.0616601722282, 'Blood Vessel': 1.144201647940075, 'Brain': 0.7357121271763816, 'Breast': 2.6461001960784314, 'Cervix Uteri': 3.253421052631579, 'Colon': 7.793533645699615, 'Esophagus': 14.337347557093423, 'Fallopian Tube': 1.1193666666666668, 'Heart': 0.671262768873403, 'Kidney': 2.6050022471910115, 'Liver': 1.3700479203539824, 'Lung': 4.880240830449827, 'Muscle': 0.2785133748443337, 'Nerve': 2.5705977382875607, 'Ovary': 1.4988983333333332, 'Pancreas': 0.459626006097561, 'Pituitary': 0.6490177738515901, 'Prostate': 1.693611836734694, 'Salivary Gland': 6.318791358024691, 'Skin': 39.24435245992261, 'Small Intestine': 14.948275401069518, 'Spleen': 16.867082987551868, 'Stomach': 7.753507520891365, 'Testis': 102.45542936288088, 'Thyroid': 3.5809618683001534, 'Uterus': 1.1763063380281689, 'Vagina': 11.839822435897435}
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[55.9, 69.13, 65.69, 71.33, 76.11, 78.06, 75.63, 74.58, 74.13, 73.88, 73.07, 69.48, 67.16, 68.04, 59.15, 53.99, 59.53, 53.69, 52.3, 54.45, 56.23, 56.36, 56.11, 64.96, 73.56, 70.0, 68.8, 73.03, 77.53, 72.34, 69.87, 67.54, 69.67, 64.48, 60.2, 54.89, 45.22, 45.55, 37.73, 44.61, 41.45, 41.12, 46.25, 38.71, 36.22, 42.83, 39.02, 40.94, 42.63, 42.38, 43.25, 43.77, 43.76, 42.94, 44.75, 47.37, 43.88, 43.41, 42.54, 46.84, 41.83, 40.56, 42.06, 43.65, 44.15, 42.79, 42.41, 39.9, 42.21, 38.81, 41.63, 43.22, 47.68, 47.9, 42.05, 43.18, 49.7, 52.19, 52.64, 55.92, 52.04, 57.9, 59.76, 67.23, 69.45, 68.9, 75.37, 76.0, 75.63, 77.34, 76.02, 77.23, 79.69, 78.89, 75.27, 74.2, 69.12, 62.43, 61.5, 52.63, 53.04, 52.78, 50.38, 47.01, 55.97, 57.48, 67.36, 76.44, 74.56, 74.52, 79.94, 81.68, 78.6, 81.92, 83.57, 81.68, 82.47, 85.94, 84.88, 83.73, 81.97, 83.58, 82.73, 80.44, 78.91, 79.2, 83.26, 84.14, 85.62, 85.57, 87.62, 87.85, 86.25, 85.06, 86.98, 81.85, 80.53, 82.36, 77.81, 69.0, 72.68, 66.21, 63.56, 55.74, 53.88, 50.94, 55.12, 56.12, 50.6, 51.38, 45.79, 40.93, 47.55, 48.7, 51.01, 57.1, 49.19, 55.55, 56.01, 49.98, 54.02, 53.11, 56.05, 62.5, 71.03, 88.06, 89.81, 93.83, 94.36, 94.42, 96.38, 97.61, 96.17, 97.05, 98.25, 98.34, 98.41, 98.3, 98.13, 97.68, 98.53, 98.62, 98.48, 98.45, 98.26, 98.73, 98.83, 98.84, 98.82, 98.76, 98.87, 98.73, 98.52, 97.63, 97.49, 98.15, 98.68, 98.65, 98.87, 98.83, 98.85, 98.7, 98.57, 98.44, 98.7, 98.83, 98.77, 98.71, 98.58, 97.86, 97.02, 95.52, 96.72, 96.39, 97.88, 98.07, 98.2, 98.41, 98.51, 98.53, 98.32, 98.24, 95.79, 96.33, 95.65, 95.8, 97.9, 98.77, 98.87, 98.87, 98.9, 98.92, 98.95, 98.86, 98.66, 97.79, 96.41, 97.53, 97.75, 98.69, 98.88, 98.94, 98.94, 98.91, 98.91, 98.69, 98.45, 98.62, 98.77, 98.89, 98.83, 98.83, 98.81, 98.48, 97.88, 96.23, 97.35, 97.55, 98.12, 98.49, 98.35, 98.58, 98.57, 98.8, 98.68, 98.63, 98.81, 98.43, 98.67, 98.76, 98.92, 98.79, 98.92, 98.95, 98.92, 98.87, 98.64, 98.28, 98.43, 98.8, 98.91, 98.94, 98.96, 98.93, 98.94, 98.84, 98.59, 98.67, 98.81, 98.94, 98.93, 98.89, 98.9, 98.77, 98.55, 98.51, 98.58, 98.45, 98.61, 98.77, 98.82, 98.63, 98.7, 98.71, 98.74, 98.43, 98.21, 98.84, 98.65, 98.65, 98.82, 98.93, 98.78, 98.78, 98.93, 98.91, 98.85, 98.69, 97.69, 97.5, 97.73, 98.18, 98.65, 98.9, 98.93, 98.94, 98.91, 98.76, 98.81, 98.7, 98.67, 98.82, 98.94, 98.93, 98.92, 98.85, 98.43, 98.02, 97.68, 97.13, 95.75, 93.94, 94.4, 96.83, 98.16, 98.26, 98.44, 98.37, 98.68, 98.84, 98.82, 98.76, 98.65, 98.68, 98.35, 97.43, 98.43, 98.86, 98.88, 98.84, 98.88, 98.89, 98.85, 98.68, 97.92, 97.88, 98.18, 97.42, 98.38, 98.75, 98.91, 98.9, 98.94, 98.8, 98.41, 96.97, 95.4, 95.1, 97.2, 97.53, 98.55, 98.85, 98.86, 98.87, 98.85, 98.69, 98.57, 97.9, 98.11, 98.26, 98.55, 98.55, 98.44, 97.94, 98.51, 98.21, 97.56, 95.94, 94.09, 96.11, 97.6, 98.67, 98.12, 98.55, 98.84, 98.88, 98.74, 97.84, 95.85, 94.34, 94.72, 96.79, 98.17, 98.27, 98.78, 98.8, 98.62, 98.7, 96.64, 93.02, 92.75, 93.94, 97.22, 98.02, 98.69, 98.45, 98.39, 98.29, 97.68, 98.16, 97.75, 97.55, 97.66, 96.19, 96.05, 95.89, 96.13, 96.75, 97.6, 97.07, 95.64, 98.21, 97.71, 97.99, 98.24, 98.65, 98.66, 97.93, 98.84, 98.77, 98.64, 98.28, 97.04, 94.92, 96.65, 96.67, 98.17, 98.78, 98.78, 98.78, 98.77, 98.78, 98.57, 98.35, 98.61, 98.66, 98.65, 98.7, 98.56, 98.49, 96.86, 96.62, 96.59, 92.53, 88.33, 79.8, 77.0, 75.08, 76.45, 77.67, 76.54, 77.21, 73.62, 75.37, 74.55, 72.89, 69.09, 61.2, 57.64, 60.49, 53.98, 68.12, 71.17, 74.04, 75.23, 68.96, 80.55, 67.87, 55.09]
[0.86, 0.74, 0.77, 0.73, 0.42, 0.64, 0.61, 0.46, 0.59, 0.42, 0.62, 0.55, 0.76, 0.67, 0.59, 0.8, 0.83, 0.7, 0.82, 0.66, 0.91, 0.93, 0.54, 0.81, 0.51, 0.37, 0.79, 0.8, 0.54, 0.5, 0.67, 0.54, 0.81, 0.78, 0.75, 0.72, 0.74, 0.94, 0.9, 0.94, 0.9, 0.99, 0.99, 1.0, 0.99, 1.0, 0.99, 1.0, 0.99, 1.0, 1.0, 0.99, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 0.99, 1.0, 0.98, 1.0, 1.0, 0.97, 0.94, 0.94, 0.85, 0.91, 0.88, 0.9, 0.93, 0.94, 0.86, 0.93, 0.98, 0.9, 0.88, 0.79, 0.62, 0.66, 0.71, 0.79, 0.77, 0.48, 0.68, 0.48, 0.85, 0.45, 0.42, 0.57, 0.61, 0.58, 0.58, 0.5, 0.65, 0.82, 0.73, 0.64, 0.85, 0.95, 0.97, 0.75, 0.6, 0.52, 0.7, 0.64, 0.64, 0.55, 0.65, 0.55, 0.65, 0.39, 0.4, 0.6, 0.14, 0.47, 0.82, 0.77, 0.5, 0.67, 0.55, 0.12, 0.52, 0.83, 0.7, 0.45, 0.88, 0.98, 0.87, 0.94, 0.87, 0.88, 0.65, 0.95, 0.89, 0.96, 0.94, 0.71, 0.65, 0.97, 0.91, 0.75, 0.92, 0.6, 0.68, 0.75, 0.76, 0.52, 0.87, 0.94, 0.33, 0.9, 0.94, 0.43, 0.91, 0.83, 0.56, 0.94, 0.53, 0.94, 0.96, 0.44, 0.98, 0.2, 0.88, 0.17, 0.32, 0.63, 0.77, 0.19, 0.62, 0.54, 0.53, 0.24, 0.8, 0.01, 0.6, 0.63, 0.07, 0.35, 0.51, 0.23, 0.1, 0.3, 0.02, 0.21, 0.04, 0.1, 0.24, 0.1, 0.01, 0.48, 0.6, 0.24, 0.23, 0.0, 0.0, 0.12, 0.01, 0.11, 0.24, 0.28, 0.05, 0.0, 0.34, 0.04, 0.1, 0.21, 0.21, 0.73, 0.59, 0.38, 0.6, 0.73, 0.38, 0.39, 0.05, 0.06, 0.64, 0.13, 0.84, 0.65, 0.95, 0.79, 0.25, 0.13, 0.01, 0.0, 0.0, 0.06, 0.06, 0.06, 0.13, 0.8, 0.71, 0.18, 0.53, 0.34, 0.0, 0.0, 0.0, 0.0, 0.0, 0.25, 0.36, 0.07, 0.18, 0.01, 0.02, 0.05, 0.13, 0.16, 0.17, 0.93, 0.75, 0.47, 0.62, 0.4, 0.49, 0.21, 0.41, 0.01, 0.62, 0.34, 0.1, 0.78, 0.27, 0.03, 0.0, 0.0, 0.01, 0.11, 0.11, 0.14, 0.3, 0.65, 0.44, 0.22, 0.0, 0.0, 0.0, 0.0, 0.0, 0.47, 0.26, 0.0, 0.34, 0.0, 0.05, 0.04, 0.0, 0.11, 0.15, 0.66, 0.49, 0.77, 0.82, 0.12, 0.45, 0.55, 0.09, 0.39, 0.0, 0.57, 0.27, 0.09, 0.78, 0.46, 0.07, 0.0, 0.0, 0.02, 0.1, 0.36, 0.07, 0.07, 0.67, 0.44, 0.16, 0.45, 0.12, 0.0, 0.0, 0.0, 0.0, 0.0, 0.26, 0.18, 0.29, 0.24, 0.0, 0.01, 0.01, 0.0, 0.18, 0.48, 0.65, 0.58, 0.64, 0.99, 0.8, 0.34, 0.22, 0.59, 0.3, 0.53, 0.24, 0.54, 0.03, 0.6, 0.4, 0.03, 0.55, 0.09, 0.1, 0.0, 0.05, 0.01, 0.04, 0.03, 0.07, 0.03, 0.55, 0.29, 0.45, 0.49, 0.27, 0.06, 0.0, 0.0, 0.0, 0.0, 0.0, 0.06, 0.42, 0.52, 0.06, 0.19, 0.28, 0.02, 0.16, 0.02, 0.0, 0.28, 0.06, 0.59, 0.62, 0.24, 0.38, 0.38, 0.51, 0.28, 0.55, 0.2, 0.32, 0.08, 0.61, 0.05, 0.13, 0.0, 0.01, 0.13, 0.02, 0.09, 0.05, 0.0, 0.51, 0.11, 0.2, 0.46, 0.03, 0.02, 0.0, 0.01, 0.0, 0.0, 0.0, 0.65, 0.41, 0.29, 0.1, 0.05, 0.0, 0.03, 0.0, 0.02, 0.38, 0.14, 0.85, 0.72, 0.09, 0.47, 0.41, 0.14, 0.2, 0.3, 0.02, 0.38, 0.41, 0.06, 0.71, 0.36, 0.28, 0.0, 0.03, 0.14, 0.04, 0.07, 0.27, 0.09, 0.41, 0.48, 0.04, 0.04, 0.12, 0.0, 0.01, 0.0, 0.01, 0.0, 0.18, 0.21, 0.46, 0.17, 0.02, 0.14, 0.04, 0.02, 0.4, 0.06, 0.0, 0.4, 0.16, 0.64, 0.66, 0.52, 0.5, 0.52, 0.67, 0.66, 0.48, 0.45, 0.75, 0.6, 0.56, 0.62, 0.81, 0.85, 0.57, 0.9, 0.84, 0.79, 0.82, 0.85, 0.67, 1.0, 0.9]
null
Component of an E-cadherin/ catenin adhesion complex composed of at least E-cadherin/CDH1, beta-catenin/CTNNB1 or gamma-catenin/JUP, and potentially alpha-catenin/CTNNA1. Forms a ternary complex composed of ADAM10, CADH1 and EPHA4,
null
null
KLRG1, SPEF1, DLGAP5, AJAP1, RAPGEF2, RAB8B, PIP5K1C, PKP2, TRPV4, CTNNB1, CAV1, DDR1, TBC1D2, CTNNA1, JUP, CTNND1, PSEN1, LIMA1, CDH1, JUP, ADAM10, CADH1 , EPHA4,
null
null
null
null
Homodimer
null
79.91949
0.474025
84.601884
0.437455
1,590
P12830
Q13309
null
degron_data
CDH1
MGPWSRSLSALLLLLQVSSWLCQEPEPCHPGFDAESYTFTVPRRHLERGRVLGRVNFEDCTGRQRTAYFSLDTRFKVGTDGVITVKRPLRFHNPQIHFLVYAWDSTYRKFSTKVTLNTVGHHHRPPPHQASVSGIQAELLTFPNSSPGLRRQKRDWVIPPISCPENEKGPFPKNLVQIKSNKDKEGKVFYSITGQGADTPPVGVFIIERETGWLKVTEPLDRERIATYTLFSHAVSSNGNAVEDPMEILITVTDQNDNKPEFTQEVFKGSVMEGALPGTSVMEVTATDADDDVNTYNAAIAYTILSQDPELPDKNMFTINRNTGVISVVTTGLDRESFPTYTLVVQAADLQGEGLSTTATAVITVTDTNDNPPIFNPTTYKGQVPENEANVVITTLKVTDADAPNTPAWEAVYTILNDDGGQFVVTTNPVNNDGILKTAKGLDFEAKQQYILHVAVTNVVPFEVSLTTSTATVTVDVLDVNEAPIFVPPEKRVEVSEDFGVGQEITSYTAQEPDTFMEQKITYRIWRDTANWLEINPDTGAISTRAELDREDFEHVKNSTYTALIIATDNGSPVATGTGTLLLILSDVNDNAPIPEPRTIFFCERNPKPQVINIIDADLPPNTSPFTAELTHGASANWTIQYNDPTQESIILKPKMALEVGDYKINLKLMDNQNKDQVTTLEVSVCDCEGAAGVCRKAQPVEAGLQIPAILGILGGILALLILILLLLLFLRRRAVVKEPLLPPEDDTRDNVYYYDEEGGGEEDQDFDLSQLHRGLDARPEVTRNDVAPTLMSVPRYLPRPANPDEIGNFIDENLKAADTDPTAPPYDSLLVFDYEGSGSEAASLSSLNSSESDKDQDYDYLNEWGNRFKKLADMYGGGEDD
Homo sapiens
Cell junction, adherens junction, Cell membrane, Endosome, Golgi apparatus, trans-Golgi network, Cytoplasm, Cell junction, desmosome
Tissue enhanced (parathyroid)
{'Ciliated cells': '119.1', 'Basal respiratory cells': '71.1', 'Club cells': '97.3', 'Ionocytes': '81.0', 'Mucus glandular cells': '155.0', 'Serous glandular cells': '67.8', 'Gastric mucus-secreting cells': '133.2', 'Proximal enterocytes': '140.9', 'Paneth cells': '125.1', 'Distal enterocytes': '307.5', 'Intestinal goblet cells': '173.5', 'Exocrine glandular cells': '-0.605', 'Basal prostatic cells': '68.3', 'Prostatic glandular cells': '186.7', 'Breast glandular cells': '0.773', 'Breast myoepithelial cells': '0.700', 'Glandular and luminal cells': '313.0', 'Secretory cells': '82.3', 'Basal keratinocytes': '102.5', 'Suprabasal keratinocytes': '162.6', 'Basal squamous epithelial cells': '51.0', 'Squamous epithelial cells': '106.9', 'Alveolar cells type 1': '0.437', 'Alveolar cells type 2': '0.706', 'Salivary duct cells': '95.9', 'Ductal cells': '0.541', 'Hepatocytes': '0.600', 'Cholangiocytes': '129.7', 'Proximal tubular cells': '0.042', 'Distal tubular cells': '0.0', 'Collecting duct cells': '143.9', 'Mesothelial cells': '0.799', 'Sertoli cells': '0.252', 'Granulosa cells': '12.9', 'Enteroendocrine cells': '92.4', 'Pancreatic endocrine cells': '78.1', 'Leydig cells': '0.264', 'Excitatory neurons': '0.7', 'Inhibitory neurons': '1.3', 'Cone photoreceptor cells': '0.0', 'Rod photoreceptor cells': '0.0', 'Bipolar cells': '0.2', 'Horizontal cells': '0.6', 'Astrocytes': '0.6', 'Oligodendrocyte precursor cells': '0.5', 'Oligodendrocytes': '29.9', 'Microglial cells': '0.9', 'Muller glia cells': '0.1', 'Schwann cells': '0.131', 'Spermatogonia': '0.392', 'Spermatocytes': '0.193', 'Early spermatids': '-0.217', 'Late spermatids': '-0.290', 'Oocytes': '16.9', 'Cytotrophoblasts': '119.2', 'Syncytiotrophoblasts': '45.0', 'Extravillous trophoblasts': '24.9', 'Endothelial cells': '6.1', 'Lymphatic endothelial cells': '0.4', 'Cardiomyocytes': '0.135', 'Skeletal myocytes': '0.107', 'Smooth muscle cells': '5.8', 'Adipocytes': '2.1', 'Melanocytes': '0.335', 'Fibroblasts': '6.5', 'Peritubular cells': '0.210', 'Endometrial stromal cells': '27.7', 'Ovarian stromal cells': '0.7', 'Undifferentiated cells': '101.6', 'T-cells': '2.9', 'B-cells': '4.4', 'Plasma cells': '6.1', 'Nk-cells': '0.0', 'Granulocytes': '8.4', 'Monocytes': '0.0', 'Macrophages': '6.0', 'Hofbauer cells': '4.3', 'Kupffer cells': '1.0', 'Dendritic cells': '5.9', 'Langerhans cells': '0.304', 'Erythroid cells': '0.036', 'Adipocytes (Subcutaneous)': '-0.081', 'Adipocytes (Visceral)': '-0.209', 'Breast glandular cells (progenitors)': '0.538', 'Adipocytes (Breast)': '-0.689', 'Colon enterocytes': '0.790', 'Colon enteroendocrine cells': '0.112', 'Enteric glia cells': '-0.048', 'Mitotic cells (Colon)': '0.299', 'Mitotic cells (Heart)': '0.120', 'Podocytes': '-0.118', 'Ascending Loop of Henle cells': '0.475', 'Intercalated cells': '0.212', 'Cholangiocyte': '0.090', 'NK-cells (Liver)': '-0.005', 'Respiratory ciliated cells': '-0.012', 'Mitotic cells (Lung)': '0.071', 'NK-cells (Lung)': '-0.266', 'B-cells (Lung)': '-0.296', 'Alpha cells': '0.270', 'Beta cells': '0.152', 'Prostate glandular cells': '0.764', 'Prostate basal glandular cells': '0.540', 'Urothelial cells': '0.205', 'Keratinocyte (other)': '0.510', 'Keratinocyte (granular)': '0.055', 'Hair cortex cells': '0.080', 'Inner root sheath cells': '0.131', 'Outer root sheath cells': '0.175', 'Sebaceous gland cells': '0.156', 'Eccrine sweat gland cells': '-0.207', 'Adipocytes (Skin)': '-0.244', 'Mitotic cells (Skin)': '0.442', 'Parietal cells': '0.654', 'Chief cells': '0.649', 'Gastric mucous cells': '0.781', 'Gastric enteroendocrine cells': '0.590', 'Mitotic cells (Stomach)': '0.445', 'Parafollicular cells': '0.173', 'Thyroid glandular cells': '0.865', 'Mitotic cells (Thyroid)': '-0.081', 'Adrenal cortex cells': '0.051', 'Adrenal medulla cells': '0.087', 'Mitotic cells (Adrenal gland)': '0.072', 'Minor salivary glandular cells': '0.371', 'Minor salivary gland ductal cells': '-0.142', 'Minor salivary gland basal cells': '0.582', 'Mitotic cells (Minor salivary gland)': '0.567', 'Adipocytes (Minor salivary gland)': '0.050', 'Somatotropes': '0.121', 'Lactotropes': '0.322', 'Gonadotropes': '0.330', 'Corticotropes': '0.180', 'Thyrotropes': '0.496', 'Undifferentiated cells (Pituitary gland)': '-0.108', 'Mitotic cells (Spleen)': '-0.228', 'Platelets': '-0.050', 'Erythrocytes': '-0.158', 'Hematopoietic stem cells': '-0.211', 'B-cells (Spleen)': '0.266', 'NK-cells (Spleen)': '0.309', 'Amygdala excitatory': '1.0', 'Cerebellar inhibitory': '0.9', 'Cge interneuron': '0.7', 'Deep-layer corticothalamic and 6b': '1.5', 'Deep-layer intratelencephalic': '0.7', 'Deep-layer near-projecting': '0.7', 'Eccentric medium spiny neuron': '0.6', 'Hippocampal ca1-3': '1.9', 'Hippocampal ca4': '1.2', 'Hippocampal dentate gyrus': '1.1', 'Lamp5-lhx6 and chandelier': '0.5', 'Lower rhombic lip': '0.8', 'Mammillary body': '0.6', 'Medium spiny neuron': '0.7', 'Mge interneuron': '1.7', 'Midbrain-derived inhibitory': '0.7', 'Miscellaneous': '0.9', 'Splatter': '3.8', 'Thalamic excitatory': '0.5', 'Upper rhombic lip': '0.8', 'Upper-layer intratelencephalic': '0.6', 'Astrocyte': '4.4', 'Bergmann glia': '0.2', 'Central nervous system macrophage': '0.6', 'Choroid plexus epithelial cell': '52.1', 'Committed oligodendrocyte precursor': '41.5', 'Ependymal cell': '4.8', 'Oligodendrocyte': '53.1', 'Oligodendrocyte precursor cell': '2.4', 'Endothelial cell': '0.7', 'Pericyte': '0.3', 'Vascular associated smooth muscle cell': '0.0', 'Fibroblast': '17.4', 'Leukocyte': '1.1', 'Basophil': '0.0', 'Eosinophil': '0.0', 'Neutrophil': '0.0', 'Classical monocyte': '0.0', 'Non-classical monocyte': '0.0', 'Intermediate monocyte': '0.0', 'T-reg': '2.3', 'GdT-cell': '0.0', 'MAIT T-cell': '0.0', 'Memory CD4 T-cell': '0.0', 'Naive CD4 T-cell': '0.1', 'Memory CD8 T-cell': '0.2', 'Naive CD8 T-cell': '0.3', 'Memory B-cell': '0.0', 'Naive B-cell': '0.1', 'Plasmacytoid DC': '46.6', 'Myeloid DC': '8.5', 'NK-cell': '0.1', 'Total PBMC': '0.7', 'Vd2 gdTCR': '0.0', 'Memory CD4 T-cell Th1\\/Th17': '0.1', 'Memory CD4 T-cell Th17': '0.2', 'Memory CD4 T-cell Th2': '2.9', 'Non-Vd2 gdTCR': '0.1', 'Memory CD4 T-cell Th1': '0.3', 'Memory CD4 T-cell TFH': '0.5', 'Terminal effector memory CD4 T-cell': '0.0', 'Central memory CD8 T-cell': '4.8', 'Effector memory CD8 T-cell': '0.0', 'Terminal effector memory CD8 T-cell': '0.6', 'Non-switched memory B-cell': '0.0', 'Plasmablast': '3.3', 'Switched memory B-cell': '0.0', 'Exhausted memory B-cell': '0.7', 'Progenitor cell': '2.3', 'Memory T-reg': '1.3', 'Naive CD4 T-cell activated': '0.3', 'Naive CD8 T-cell activated': '0.6', 'Naive T-reg': '0.1'}
1O6S, 2O72, 2OMT, 2OMU, 2OMV, 2OMX, 2OMY, 2OMZ, 3FF7, 3FF8, 3L6X, 3L6Y, 4ZT1, 4ZTE, 6CXY, 6OLE, 6OLF, 6OLG, 6VEL, 7STZ, 8H62
{'Adipose Tissue': 1.2125261088039867, 'Adrenal Gland': 0.1914223992248062, 'Bladder': 39.2033519047619, 'Blood': 1.340954264800861, 'Blood Vessel': 0.3121561692883895, 'Brain': 0.8550442199091597, 'Breast': 38.54918344226579, 'Cervix Uteri': 23.539115789473684, 'Colon': 43.41292142490372, 'Esophagus': 53.97513367404844, 'Fallopian Tube': 14.900277777777776, 'Heart': 0.119140469221835, 'Kidney': 25.040449438202245, 'Liver': 26.60802654867257, 'Lung': 35.447986366782004, 'Muscle': 0.1378936151930261, 'Nerve': 17.518468982229404, 'Ovary': 3.6515122222222223, 'Pancreas': 56.89676829268293, 'Pituitary': 24.68741660777385, 'Prostate': 61.279967346938776, 'Salivary Gland': 92.01685185185184, 'Skin': 79.77571720232172, 'Small Intestine': 71.7519320855615, 'Spleen': 10.061029045643156, 'Stomach': 58.07813805013927, 'Testis': 0.8144204986149585, 'Thyroid': 135.176797856049, 'Uterus': 1.442593943661972, 'Vagina': 86.52345512820513}
SKP2
MHRKHLQEIPDLSSNVATSFTWGWDSSKTSELLSGMGVSALEKEEPDSENIPQELLSNLGHPESPPRKRLKSKGSDKDFVIVRRPKLNRENFPGVSWDSLPDELLLGIFSCLCLPELLKVSGVCKRWYRLASDESLWQTLDLTGKNLHPDVTGRLLSQGVIAFRCPRSFMDQPLAEHFSPFRVQHMDLSNSVIEVSTLHGILSQCSKLQNLSLEGLRLSDPIVNTLAKNSNLVRLNLSGCSGFSEFALQTLLSSCSRLDELNLSWCFDFTEKHVQVAVAHVSETITQLNLSGYRKNLQKSDLSTLVRRCPNLVHLDLSDSVMLKNDCFQEFFQLNYLQHLSLSRCYDIIPETLLELGEIPTLKTLQVFGIVPDGTLQLLKEALPHLQINCSHFTTIARPTIGNKKNQEIWGIKCRLTLQKPSCL
Homo sapiens
Cytoplasm, Nucleus
Tissue enhanced (placenta)
{'Ciliated cells': '5.4', 'Basal respiratory cells': '6.6', 'Club cells': '3.4', 'Ionocytes': '2.9', 'Mucus glandular cells': '2.5', 'Serous glandular cells': '6.3', 'Gastric mucus-secreting cells': '7.7', 'Proximal enterocytes': '3.5', 'Paneth cells': '4.2', 'Distal enterocytes': '2.0', 'Intestinal goblet cells': '5.2', 'Exocrine glandular cells': '-0.448', 'Basal prostatic cells': '3.7', 'Prostatic glandular cells': '5.6', 'Breast glandular cells': '0.282', 'Breast myoepithelial cells': '0.316', 'Glandular and luminal cells': '2.6', 'Secretory cells': '3.2', 'Basal keratinocytes': '8.0', 'Suprabasal keratinocytes': '5.7', 'Basal squamous epithelial cells': '14.8', 'Squamous epithelial cells': '19.7', 'Alveolar cells type 1': '-0.120', 'Alveolar cells type 2': '-0.162', 'Salivary duct cells': '3.9', 'Ductal cells': '0.507', 'Hepatocytes': '0.683', 'Cholangiocytes': '1.9', 'Proximal tubular cells': '0.096', 'Distal tubular cells': '0.0', 'Collecting duct cells': '3.9', 'Mesothelial cells': '0.485', 'Sertoli cells': '0.517', 'Granulosa cells': '8.9', 'Enteroendocrine cells': '4.1', 'Pancreatic endocrine cells': '1.7', 'Leydig cells': '0.631', 'Excitatory neurons': '21.7', 'Inhibitory neurons': '12.6', 'Cone photoreceptor cells': '8.5', 'Rod photoreceptor cells': '14.3', 'Bipolar cells': '11.4', 'Horizontal cells': '9.4', 'Astrocytes': '11.1', 'Oligodendrocyte precursor cells': '10.8', 'Oligodendrocytes': '27.5', 'Microglial cells': '11.6', 'Muller glia cells': '3.8', 'Schwann cells': '0.183', 'Spermatogonia': '0.620', 'Spermatocytes': '0.278', 'Early spermatids': '-0.325', 'Late spermatids': '-0.687', 'Oocytes': '35.3', 'Cytotrophoblasts': '143.4', 'Syncytiotrophoblasts': '70.7', 'Extravillous trophoblasts': '230.0', 'Endothelial cells': '4.7', 'Lymphatic endothelial cells': '5.5', 'Cardiomyocytes': '0.369', 'Skeletal myocytes': '0.067', 'Smooth muscle cells': '7.2', 'Adipocytes': '4.5', 'Melanocytes': '0.249', 'Fibroblasts': '8.0', 'Peritubular cells': '0.607', 'Endometrial stromal cells': '7.4', 'Ovarian stromal cells': '5.5', 'Undifferentiated cells': '15.8', 'T-cells': '6.8', 'B-cells': '7.9', 'Plasma cells': '12.6', 'Nk-cells': '9.4', 'Granulocytes': '7.0', 'Monocytes': '5.2', 'Macrophages': '6.2', 'Hofbauer cells': '21.8', 'Kupffer cells': '9.1', 'Dendritic cells': '5.2', 'Langerhans cells': '0.337', 'Erythroid cells': '0.015', 'Adipocytes (Subcutaneous)': '0.132', 'Adipocytes (Visceral)': '-0.220', 'Breast glandular cells (progenitors)': '0.188', 'Adipocytes (Breast)': '-0.192', 'Colon enterocytes': '-0.041', 'Colon enteroendocrine cells': '0.184', 'Enteric glia cells': '0.342', 'Mitotic cells (Colon)': '0.003', 'Mitotic cells (Heart)': '0.487', 'Podocytes': '-0.124', 'Ascending Loop of Henle cells': '0.475', 'Intercalated cells': '-0.015', 'Cholangiocyte': '-0.108', 'NK-cells (Liver)': '0.142', 'Respiratory ciliated cells': '0.079', 'Mitotic cells (Lung)': '0.252', 'NK-cells (Lung)': '0.034', 'B-cells (Lung)': '-0.002', 'Alpha cells': '0.440', 'Beta cells': '0.319', 'Prostate glandular cells': '-0.189', 'Prostate basal glandular cells': '0.201', 'Urothelial cells': '0.203', 'Keratinocyte (other)': '0.274', 'Keratinocyte (granular)': '-0.308', 'Hair cortex cells': '-0.030', 'Inner root sheath cells': '0.057', 'Outer root sheath cells': '0.265', 'Sebaceous gland cells': '0.266', 'Eccrine sweat gland cells': '-0.028', 'Adipocytes (Skin)': '-0.163', 'Mitotic cells (Skin)': '0.554', 'Parietal cells': '-0.361', 'Chief cells': '-0.294', 'Gastric mucous cells': '-0.120', 'Gastric enteroendocrine cells': '-0.099', 'Mitotic cells (Stomach)': '0.251', 'Parafollicular cells': '0.001', 'Thyroid glandular cells': '0.107', 'Mitotic cells (Thyroid)': '0.219', 'Adrenal cortex cells': '0.381', 'Adrenal medulla cells': '0.086', 'Mitotic cells (Adrenal gland)': '0.411', 'Minor salivary glandular cells': '-0.035', 'Minor salivary gland ductal cells': '-0.108', 'Minor salivary gland basal cells': '0.640', 'Mitotic cells (Minor salivary gland)': '0.673', 'Adipocytes (Minor salivary gland)': '0.168', 'Somatotropes': '0.027', 'Lactotropes': '0.300', 'Gonadotropes': '0.261', 'Corticotropes': '-0.069', 'Thyrotropes': '0.243', 'Undifferentiated cells (Pituitary gland)': '0.041', 'Mitotic cells (Spleen)': '0.095', 'Platelets': '-0.115', 'Erythrocytes': '-0.028', 'Hematopoietic stem cells': '-0.133', 'B-cells (Spleen)': '0.298', 'NK-cells (Spleen)': '0.278', 'Amygdala excitatory': '23.6', 'Cerebellar inhibitory': '17.5', 'Cge interneuron': '13.4', 'Deep-layer corticothalamic and 6b': '23.5', 'Deep-layer intratelencephalic': '31.2', 'Deep-layer near-projecting': '17.0', 'Eccentric medium spiny neuron': '16.5', 'Hippocampal ca1-3': '22.7', 'Hippocampal ca4': '19.7', 'Hippocampal dentate gyrus': '14.3', 'Lamp5-lhx6 and chandelier': '14.7', 'Lower rhombic lip': '13.5', 'Mammillary body': '21.8', 'Medium spiny neuron': '15.7', 'Mge interneuron': '18.2', 'Midbrain-derived inhibitory': '27.0', 'Miscellaneous': '29.5', 'Splatter': '15.9', 'Thalamic excitatory': '16.4', 'Upper rhombic lip': '20.4', 'Upper-layer intratelencephalic': '29.2', 'Astrocyte': '19.8', 'Bergmann glia': '11.8', 'Central nervous system macrophage': '40.2', 'Choroid plexus epithelial cell': '23.8', 'Committed oligodendrocyte precursor': '20.0', 'Ependymal cell': '20.8', 'Oligodendrocyte': '37.8', 'Oligodendrocyte precursor cell': '18.2', 'Endothelial cell': '13.4', 'Pericyte': '12.7', 'Vascular associated smooth muscle cell': '12.3', 'Fibroblast': '13.0', 'Leukocyte': '14.0', 'Basophil': '59.3', 'Eosinophil': '13.5', 'Neutrophil': '7.6', 'Classical monocyte': '9.4', 'Non-classical monocyte': '19.3', 'Intermediate monocyte': '19.5', 'T-reg': '22.5', 'GdT-cell': '4.2', 'MAIT T-cell': '24.8', 'Memory CD4 T-cell': '4.7', 'Naive CD4 T-cell': '22.6', 'Memory CD8 T-cell': '4.6', 'Naive CD8 T-cell': '19.4', 'Memory B-cell': '5.2', 'Naive B-cell': '22.5', 'Plasmacytoid DC': '14.8', 'Myeloid DC': '30.4', 'NK-cell': '21.9', 'Total PBMC': '19.2', 'Vd2 gdTCR': '18.9', 'Memory CD4 T-cell Th1\\/Th17': '15.1', 'Memory CD4 T-cell Th17': '16.3', 'Memory CD4 T-cell Th2': '20.6', 'Non-Vd2 gdTCR': '21.7', 'Memory CD4 T-cell Th1': '16.0', 'Memory CD4 T-cell TFH': '17.3', 'Terminal effector memory CD4 T-cell': '31.0', 'Central memory CD8 T-cell': '14.7', 'Effector memory CD8 T-cell': '19.4', 'Terminal effector memory CD8 T-cell': '21.4', 'Non-switched memory B-cell': '24.5', 'Plasmablast': '19.5', 'Switched memory B-cell': '24.4', 'Exhausted memory B-cell': '26.1', 'Progenitor cell': '21.6', 'Memory T-reg': '22.5', 'Naive CD4 T-cell activated': '15.1', 'Naive CD8 T-cell activated': '13.8', 'Naive T-reg': '23.4'}
1FQV, 1FS1, 1FS2, 1LDK, 2ASS, 2AST, 7B5L, 7B5M, 7B5R, 7LUO, 7Z8T, 7Z8V, 7ZBW, 7ZBZ, 8BYA, 8BYL, 8CDJ, 8CDK, 8OR0, 8OR3, 8OR4
{'Adipose Tissue': 7.884296760797342, 'Adrenal Gland': 6.029375968992248, 'Bladder': 8.704190476190476, 'Blood': 6.908304413347686, 'Blood Vessel': 5.634626367041198, 'Brain': 5.270861279333838, 'Breast': 7.036501089324618, 'Cervix Uteri': 11.363368421052632, 'Colon': 6.723202824133504, 'Esophagus': 8.647209965397924, 'Fallopian Tube': 10.392666666666663, 'Heart': 1.978051800232288, 'Kidney': 2.9395595505617975, 'Liver': 7.151542477876106, 'Lung': 7.259957093425605, 'Muscle': 1.7041732254047322, 'Nerve': 11.215163166397415, 'Ovary': 10.0352, 'Pancreas': 2.847617987804878, 'Pituitary': 8.211869257950529, 'Prostate': 7.6942612244897965, 'Salivary Gland': 6.274617283950618, 'Skin': 14.034285793255943, 'Small Intestine': 8.87992513368984, 'Spleen': 10.67515767634855, 'Stomach': 4.871679944289694, 'Testis': 5.268631578947368, 'Thyroid': 7.199923430321593, 'Uterus': 11.76773943661972, 'Vagina': 11.179852564102564}
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[1.0, 0.96, 0.97, 0.95, 0.91, 0.96, 0.92, 0.94, 0.94, 0.78, 0.92, 0.77, 0.91, 0.63, 0.93, 0.69, 0.75, 0.67, 0.69, 0.75, 0.79, 0.77, 0.85, 0.42, 0.62, 0.67, 0.44, 0.59, 0.33, 0.45, 0.73, 0.3, 0.17, 0.63, 0.25, 0.07, 0.73, 0.31, 0.9, 0.68, 0.92, 0.89, 0.93, 0.94, 0.94, 0.98, 0.96, 1.0, 1.0, 0.97, 0.9, 0.89, 0.91, 0.94, 0.94, 1.0, 0.89, 1.0, 1.0, 0.89, 0.98, 0.96, 0.92, 0.95, 0.93, 0.87, 0.98, 0.85, 0.96, 0.9, 0.95, 0.97, 0.95, 0.96, 0.74, 0.93, 0.82, 0.8, 0.91, 0.71, 0.82, 0.78, 0.88, 0.92, 0.84, 0.86, 0.82, 0.86, 0.81, 0.8, 0.93, 0.82, 0.94, 0.75, 0.81, 0.52, 0.63, 0.56, 0.69, 0.24, 0.51, 0.27, 0.75, 0.54, 0.03, 0.18, 0.41, 0.46, 0.02, 0.43, 0.83, 0.26, 0.31, 0.04, 0.48, 0.39, 0.01, 0.14, 0.68, 0.16, 0.09, 0.83, 0.63, 0.39, 0.87, 0.27, 0.25, 0.44, 0.62, 0.01, 0.03, 0.34, 0.3, 0.36, 0.53, 0.03, 0.02, 0.45, 0.17, 0.0, 0.08, 0.06, 0.16, 0.35, 0.19, 0.49, 0.11, 0.31, 0.0, 0.11, 0.16, 0.01, 0.01, 0.23, 0.04, 0.01, 0.48, 0.16, 0.04, 0.0, 0.28, 0.01, 0.01, 0.11, 0.0, 0.06, 0.58, 0.0, 0.48, 0.0, 0.71, 0.49, 0.67, 0.28, 0.71, 0.4, 0.96, 0.18, 0.67, 0.73, 0.01, 0.48, 0.0, 0.3, 0.13, 0.0, 0.03, 0.02, 0.11, 0.53, 0.09, 0.47, 0.13, 0.4, 0.33, 0.52, 0.0, 0.0, 0.34, 0.29, 0.03, 0.0, 0.29, 0.27, 0.0, 0.48, 0.53, 0.0, 0.35, 0.05, 0.0, 0.0, 0.0, 0.12, 0.49, 0.03, 0.54, 0.02, 0.22, 0.31, 0.5, 0.0, 0.0, 0.43, 0.09, 0.01, 0.16, 0.49, 0.0, 0.37, 0.5, 0.0, 0.31, 0.29, 0.01, 0.0, 0.0, 0.11, 0.26, 0.0, 0.04, 0.26, 0.05, 0.26, 0.19, 0.73, 0.01, 0.01, 0.36, 0.46, 0.0, 0.03, 0.53, 0.27, 0.01, 0.56, 0.68, 0.0, 0.28, 0.11, 0.0, 0.0, 0.0, 0.03, 0.36, 0.02, 0.75, 0.42, 0.06, 0.47, 0.46, 0.57, 0.07, 0.02, 0.47, 0.11, 0.01, 0.03, 0.46, 0.28, 0.01, 0.13, 0.57, 0.42, 0.0, 0.24, 0.17, 0.0, 0.01, 0.02, 0.04, 0.15, 0.05, 0.46, 0.73, 0.17, 0.03, 0.34, 0.33, 0.62, 0.08, 0.02, 0.28, 0.24, 0.01, 0.04, 0.79, 0.25, 0.0, 0.43, 0.4, 0.0, 0.24, 0.23, 0.01, 0.12, 0.02, 0.09, 0.04, 0.0, 0.25, 0.42, 0.0, 0.44, 0.3, 0.5, 0.0, 0.0, 0.73, 0.18, 0.0, 0.34, 0.51, 0.01, 0.67, 0.57, 0.0, 0.41, 0.26, 0.0, 0.17, 0.0, 0.06, 0.38, 0.0, 0.58, 0.41, 0.03, 0.56, 0.26, 0.71, 0.13, 0.0, 0.5, 0.37, 0.0, 0.17, 0.65, 0.01, 0.82, 0.29, 0.0, 0.49, 0.13, 0.0, 0.06, 0.0, 0.23, 0.69, 0.1, 0.15, 0.6, 0.77, 0.71, 0.35, 0.17, 0.55, 0.58, 0.04, 0.35, 0.61, 0.53, 0.06, 0.75, 0.6, 0.08, 0.56, 0.05, 0.16, 0.48, 0.52, 0.77, 0.91, 0.29, 0.39, 0.04, 0.0, 0.33, 0.08, 0.32, 0.67, 0.81, 0.97, 0.76, 0.87, 0.36, 0.28, 0.33, 0.0, 0.19, 0.73, 0.29, 0.74, 0.02, 0.38, 0.0, 0.09, 0.24, 0.57, 0.96, 0.59, 0.91, 0.91, 0.97]
null
Component of an E-cadherin/ catenin adhesion complex composed of at least E-cadherin/CDH1, beta-catenin/CTNNB1 or gamma-catenin/JUP, and potentially alpha-catenin/CTNNA1. Forms a ternary complex composed of ADAM10, CADH1 and EPHA4,
null
null
KLRG1, SPEF1, DLGAP5, AJAP1, RAPGEF2, RAB8B, PIP5K1C, PKP2, TRPV4, CTNNB1, CAV1, DDR1, TBC1D2, CTNNA1, JUP, CTNND1, PSEN1, LIMA1, CDH1, JUP, ADAM10, CADH1 , EPHA4,
null
null
null
null
Homodimer
null
79.91949
0.474025
82.227665
0.401627
1,873
P12830
Q13309-2
null
degron_data
CDH1
MGPWSRSLSALLLLLQVSSWLCQEPEPCHPGFDAESYTFTVPRRHLERGRVLGRVNFEDCTGRQRTAYFSLDTRFKVGTDGVITVKRPLRFHNPQIHFLVYAWDSTYRKFSTKVTLNTVGHHHRPPPHQASVSGIQAELLTFPNSSPGLRRQKRDWVIPPISCPENEKGPFPKNLVQIKSNKDKEGKVFYSITGQGADTPPVGVFIIERETGWLKVTEPLDRERIATYTLFSHAVSSNGNAVEDPMEILITVTDQNDNKPEFTQEVFKGSVMEGALPGTSVMEVTATDADDDVNTYNAAIAYTILSQDPELPDKNMFTINRNTGVISVVTTGLDRESFPTYTLVVQAADLQGEGLSTTATAVITVTDTNDNPPIFNPTTYKGQVPENEANVVITTLKVTDADAPNTPAWEAVYTILNDDGGQFVVTTNPVNNDGILKTAKGLDFEAKQQYILHVAVTNVVPFEVSLTTSTATVTVDVLDVNEAPIFVPPEKRVEVSEDFGVGQEITSYTAQEPDTFMEQKITYRIWRDTANWLEINPDTGAISTRAELDREDFEHVKNSTYTALIIATDNGSPVATGTGTLLLILSDVNDNAPIPEPRTIFFCERNPKPQVINIIDADLPPNTSPFTAELTHGASANWTIQYNDPTQESIILKPKMALEVGDYKINLKLMDNQNKDQVTTLEVSVCDCEGAAGVCRKAQPVEAGLQIPAILGILGGILALLILILLLLLFLRRRAVVKEPLLPPEDDTRDNVYYYDEEGGGEEDQDFDLSQLHRGLDARPEVTRNDVAPTLMSVPRYLPRPANPDEIGNFIDENLKAADTDPTAPPYDSLLVFDYEGSGSEAASLSSLNSSESDKDQDYDYLNEWGNRFKKLADMYGGGEDD
Homo sapiens
Cell junction, adherens junction, Cell membrane, Endosome, Golgi apparatus, trans-Golgi network, Cytoplasm, Cell junction, desmosome
Tissue enhanced (parathyroid)
{'Ciliated cells': '119.1', 'Basal respiratory cells': '71.1', 'Club cells': '97.3', 'Ionocytes': '81.0', 'Mucus glandular cells': '155.0', 'Serous glandular cells': '67.8', 'Gastric mucus-secreting cells': '133.2', 'Proximal enterocytes': '140.9', 'Paneth cells': '125.1', 'Distal enterocytes': '307.5', 'Intestinal goblet cells': '173.5', 'Exocrine glandular cells': '-0.605', 'Basal prostatic cells': '68.3', 'Prostatic glandular cells': '186.7', 'Breast glandular cells': '0.773', 'Breast myoepithelial cells': '0.700', 'Glandular and luminal cells': '313.0', 'Secretory cells': '82.3', 'Basal keratinocytes': '102.5', 'Suprabasal keratinocytes': '162.6', 'Basal squamous epithelial cells': '51.0', 'Squamous epithelial cells': '106.9', 'Alveolar cells type 1': '0.437', 'Alveolar cells type 2': '0.706', 'Salivary duct cells': '95.9', 'Ductal cells': '0.541', 'Hepatocytes': '0.600', 'Cholangiocytes': '129.7', 'Proximal tubular cells': '0.042', 'Distal tubular cells': '0.0', 'Collecting duct cells': '143.9', 'Mesothelial cells': '0.799', 'Sertoli cells': '0.252', 'Granulosa cells': '12.9', 'Enteroendocrine cells': '92.4', 'Pancreatic endocrine cells': '78.1', 'Leydig cells': '0.264', 'Excitatory neurons': '0.7', 'Inhibitory neurons': '1.3', 'Cone photoreceptor cells': '0.0', 'Rod photoreceptor cells': '0.0', 'Bipolar cells': '0.2', 'Horizontal cells': '0.6', 'Astrocytes': '0.6', 'Oligodendrocyte precursor cells': '0.5', 'Oligodendrocytes': '29.9', 'Microglial cells': '0.9', 'Muller glia cells': '0.1', 'Schwann cells': '0.131', 'Spermatogonia': '0.392', 'Spermatocytes': '0.193', 'Early spermatids': '-0.217', 'Late spermatids': '-0.290', 'Oocytes': '16.9', 'Cytotrophoblasts': '119.2', 'Syncytiotrophoblasts': '45.0', 'Extravillous trophoblasts': '24.9', 'Endothelial cells': '6.1', 'Lymphatic endothelial cells': '0.4', 'Cardiomyocytes': '0.135', 'Skeletal myocytes': '0.107', 'Smooth muscle cells': '5.8', 'Adipocytes': '2.1', 'Melanocytes': '0.335', 'Fibroblasts': '6.5', 'Peritubular cells': '0.210', 'Endometrial stromal cells': '27.7', 'Ovarian stromal cells': '0.7', 'Undifferentiated cells': '101.6', 'T-cells': '2.9', 'B-cells': '4.4', 'Plasma cells': '6.1', 'Nk-cells': '0.0', 'Granulocytes': '8.4', 'Monocytes': '0.0', 'Macrophages': '6.0', 'Hofbauer cells': '4.3', 'Kupffer cells': '1.0', 'Dendritic cells': '5.9', 'Langerhans cells': '0.304', 'Erythroid cells': '0.036', 'Adipocytes (Subcutaneous)': '-0.081', 'Adipocytes (Visceral)': '-0.209', 'Breast glandular cells (progenitors)': '0.538', 'Adipocytes (Breast)': '-0.689', 'Colon enterocytes': '0.790', 'Colon enteroendocrine cells': '0.112', 'Enteric glia cells': '-0.048', 'Mitotic cells (Colon)': '0.299', 'Mitotic cells (Heart)': '0.120', 'Podocytes': '-0.118', 'Ascending Loop of Henle cells': '0.475', 'Intercalated cells': '0.212', 'Cholangiocyte': '0.090', 'NK-cells (Liver)': '-0.005', 'Respiratory ciliated cells': '-0.012', 'Mitotic cells (Lung)': '0.071', 'NK-cells (Lung)': '-0.266', 'B-cells (Lung)': '-0.296', 'Alpha cells': '0.270', 'Beta cells': '0.152', 'Prostate glandular cells': '0.764', 'Prostate basal glandular cells': '0.540', 'Urothelial cells': '0.205', 'Keratinocyte (other)': '0.510', 'Keratinocyte (granular)': '0.055', 'Hair cortex cells': '0.080', 'Inner root sheath cells': '0.131', 'Outer root sheath cells': '0.175', 'Sebaceous gland cells': '0.156', 'Eccrine sweat gland cells': '-0.207', 'Adipocytes (Skin)': '-0.244', 'Mitotic cells (Skin)': '0.442', 'Parietal cells': '0.654', 'Chief cells': '0.649', 'Gastric mucous cells': '0.781', 'Gastric enteroendocrine cells': '0.590', 'Mitotic cells (Stomach)': '0.445', 'Parafollicular cells': '0.173', 'Thyroid glandular cells': '0.865', 'Mitotic cells (Thyroid)': '-0.081', 'Adrenal cortex cells': '0.051', 'Adrenal medulla cells': '0.087', 'Mitotic cells (Adrenal gland)': '0.072', 'Minor salivary glandular cells': '0.371', 'Minor salivary gland ductal cells': '-0.142', 'Minor salivary gland basal cells': '0.582', 'Mitotic cells (Minor salivary gland)': '0.567', 'Adipocytes (Minor salivary gland)': '0.050', 'Somatotropes': '0.121', 'Lactotropes': '0.322', 'Gonadotropes': '0.330', 'Corticotropes': '0.180', 'Thyrotropes': '0.496', 'Undifferentiated cells (Pituitary gland)': '-0.108', 'Mitotic cells (Spleen)': '-0.228', 'Platelets': '-0.050', 'Erythrocytes': '-0.158', 'Hematopoietic stem cells': '-0.211', 'B-cells (Spleen)': '0.266', 'NK-cells (Spleen)': '0.309', 'Amygdala excitatory': '1.0', 'Cerebellar inhibitory': '0.9', 'Cge interneuron': '0.7', 'Deep-layer corticothalamic and 6b': '1.5', 'Deep-layer intratelencephalic': '0.7', 'Deep-layer near-projecting': '0.7', 'Eccentric medium spiny neuron': '0.6', 'Hippocampal ca1-3': '1.9', 'Hippocampal ca4': '1.2', 'Hippocampal dentate gyrus': '1.1', 'Lamp5-lhx6 and chandelier': '0.5', 'Lower rhombic lip': '0.8', 'Mammillary body': '0.6', 'Medium spiny neuron': '0.7', 'Mge interneuron': '1.7', 'Midbrain-derived inhibitory': '0.7', 'Miscellaneous': '0.9', 'Splatter': '3.8', 'Thalamic excitatory': '0.5', 'Upper rhombic lip': '0.8', 'Upper-layer intratelencephalic': '0.6', 'Astrocyte': '4.4', 'Bergmann glia': '0.2', 'Central nervous system macrophage': '0.6', 'Choroid plexus epithelial cell': '52.1', 'Committed oligodendrocyte precursor': '41.5', 'Ependymal cell': '4.8', 'Oligodendrocyte': '53.1', 'Oligodendrocyte precursor cell': '2.4', 'Endothelial cell': '0.7', 'Pericyte': '0.3', 'Vascular associated smooth muscle cell': '0.0', 'Fibroblast': '17.4', 'Leukocyte': '1.1', 'Basophil': '0.0', 'Eosinophil': '0.0', 'Neutrophil': '0.0', 'Classical monocyte': '0.0', 'Non-classical monocyte': '0.0', 'Intermediate monocyte': '0.0', 'T-reg': '2.3', 'GdT-cell': '0.0', 'MAIT T-cell': '0.0', 'Memory CD4 T-cell': '0.0', 'Naive CD4 T-cell': '0.1', 'Memory CD8 T-cell': '0.2', 'Naive CD8 T-cell': '0.3', 'Memory B-cell': '0.0', 'Naive B-cell': '0.1', 'Plasmacytoid DC': '46.6', 'Myeloid DC': '8.5', 'NK-cell': '0.1', 'Total PBMC': '0.7', 'Vd2 gdTCR': '0.0', 'Memory CD4 T-cell Th1\\/Th17': '0.1', 'Memory CD4 T-cell Th17': '0.2', 'Memory CD4 T-cell Th2': '2.9', 'Non-Vd2 gdTCR': '0.1', 'Memory CD4 T-cell Th1': '0.3', 'Memory CD4 T-cell TFH': '0.5', 'Terminal effector memory CD4 T-cell': '0.0', 'Central memory CD8 T-cell': '4.8', 'Effector memory CD8 T-cell': '0.0', 'Terminal effector memory CD8 T-cell': '0.6', 'Non-switched memory B-cell': '0.0', 'Plasmablast': '3.3', 'Switched memory B-cell': '0.0', 'Exhausted memory B-cell': '0.7', 'Progenitor cell': '2.3', 'Memory T-reg': '1.3', 'Naive CD4 T-cell activated': '0.3', 'Naive CD8 T-cell activated': '0.6', 'Naive T-reg': '0.1'}
1O6S, 2O72, 2OMT, 2OMU, 2OMV, 2OMX, 2OMY, 2OMZ, 3FF7, 3FF8, 3L6X, 3L6Y, 4ZT1, 4ZTE, 6CXY, 6OLE, 6OLF, 6OLG, 6VEL, 7STZ, 8H62
{'Adipose Tissue': 1.2125261088039867, 'Adrenal Gland': 0.1914223992248062, 'Bladder': 39.2033519047619, 'Blood': 1.340954264800861, 'Blood Vessel': 0.3121561692883895, 'Brain': 0.8550442199091597, 'Breast': 38.54918344226579, 'Cervix Uteri': 23.539115789473684, 'Colon': 43.41292142490372, 'Esophagus': 53.97513367404844, 'Fallopian Tube': 14.900277777777776, 'Heart': 0.119140469221835, 'Kidney': 25.040449438202245, 'Liver': 26.60802654867257, 'Lung': 35.447986366782004, 'Muscle': 0.1378936151930261, 'Nerve': 17.518468982229404, 'Ovary': 3.6515122222222223, 'Pancreas': 56.89676829268293, 'Pituitary': 24.68741660777385, 'Prostate': 61.279967346938776, 'Salivary Gland': 92.01685185185184, 'Skin': 79.77571720232172, 'Small Intestine': 71.7519320855615, 'Spleen': 10.061029045643156, 'Stomach': 58.07813805013927, 'Testis': 0.8144204986149585, 'Thyroid': 135.176797856049, 'Uterus': 1.442593943661972, 'Vagina': 86.52345512820513}
SKP2
MHRKHLQEIPDLSSNVATSFTWGWDSSKTSELLSGMGVSALEKEEPDSENIPQELLSNLGHPESPPRKRLKSKGSDKDFVIVRRPKLNRENFPGVSWDSLPDELLLGIFSCLCLPELLKVSGVCKRWYRLASDESLWQTLDLTGKNLHPDVTGRLLSQGVIAFRCPRSFMDQPLAEHFSPFRVQHMDLSNSVIEVSTLHGILSQCSKLQNLSLEGLRLSDPIVNTLAKNSNLVRLNLSGCSGFSEFALQTLLSSCSRLDELNLSWCFDFTEKHVQVAVAHVSETITQLNLSGYRKNLQKSDLSTLVRRCPNLVHLDLSDSVMLKNDCFQEFFQLNYLQHLSLSRCYDIIPETLLLVTRAGVRIRLDSDIGCPQTYRTSKLKSSHKLFCQHVRVICIFVCDFYFYRLVLKQ
Homo sapiens
null
Not found
{}
null
{'Adipose Tissue': 7.884296760797342, 'Adrenal Gland': 6.029375968992248, 'Bladder': 8.704190476190476, 'Blood': 6.908304413347686, 'Blood Vessel': 5.634626367041198, 'Brain': 5.270861279333838, 'Breast': 7.036501089324618, 'Cervix Uteri': 11.363368421052632, 'Colon': 6.723202824133504, 'Esophagus': 8.647209965397924, 'Fallopian Tube': 10.392666666666663, 'Heart': 1.978051800232288, 'Kidney': 2.9395595505617975, 'Liver': 7.151542477876106, 'Lung': 7.259957093425605, 'Muscle': 1.7041732254047322, 'Nerve': 11.215163166397415, 'Ovary': 10.0352, 'Pancreas': 2.847617987804878, 'Pituitary': 8.211869257950529, 'Prostate': 7.6942612244897965, 'Salivary Gland': 6.274617283950618, 'Skin': 14.034285793255943, 'Small Intestine': 8.87992513368984, 'Spleen': 10.67515767634855, 'Stomach': 4.871679944289694, 'Testis': 5.268631578947368, 'Thyroid': 7.199923430321593, 'Uterus': 11.76773943661972, 'Vagina': 11.179852564102564}
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null
null
null
Component of an E-cadherin/ catenin adhesion complex composed of at least E-cadherin/CDH1, beta-catenin/CTNNB1 or gamma-catenin/JUP, and potentially alpha-catenin/CTNNA1. Forms a ternary complex composed of ADAM10, CADH1 and EPHA4,
null
null
KLRG1, SPEF1, DLGAP5, AJAP1, RAPGEF2, RAB8B, PIP5K1C, PKP2, TRPV4, CTNNB1, CAV1, DDR1, TBC1D2, CTNNA1, JUP, CTNND1, PSEN1, LIMA1, CDH1, JUP, ADAM10, CADH1 , EPHA4,
null
null
null
null
Homodimer
null
79.91949
0.474025
null
null
1,873
P12830
Q14807
null
degron_data
CDH1
MGPWSRSLSALLLLLQVSSWLCQEPEPCHPGFDAESYTFTVPRRHLERGRVLGRVNFEDCTGRQRTAYFSLDTRFKVGTDGVITVKRPLRFHNPQIHFLVYAWDSTYRKFSTKVTLNTVGHHHRPPPHQASVSGIQAELLTFPNSSPGLRRQKRDWVIPPISCPENEKGPFPKNLVQIKSNKDKEGKVFYSITGQGADTPPVGVFIIERETGWLKVTEPLDRERIATYTLFSHAVSSNGNAVEDPMEILITVTDQNDNKPEFTQEVFKGSVMEGALPGTSVMEVTATDADDDVNTYNAAIAYTILSQDPELPDKNMFTINRNTGVISVVTTGLDRESFPTYTLVVQAADLQGEGLSTTATAVITVTDTNDNPPIFNPTTYKGQVPENEANVVITTLKVTDADAPNTPAWEAVYTILNDDGGQFVVTTNPVNNDGILKTAKGLDFEAKQQYILHVAVTNVVPFEVSLTTSTATVTVDVLDVNEAPIFVPPEKRVEVSEDFGVGQEITSYTAQEPDTFMEQKITYRIWRDTANWLEINPDTGAISTRAELDREDFEHVKNSTYTALIIATDNGSPVATGTGTLLLILSDVNDNAPIPEPRTIFFCERNPKPQVINIIDADLPPNTSPFTAELTHGASANWTIQYNDPTQESIILKPKMALEVGDYKINLKLMDNQNKDQVTTLEVSVCDCEGAAGVCRKAQPVEAGLQIPAILGILGGILALLILILLLLLFLRRRAVVKEPLLPPEDDTRDNVYYYDEEGGGEEDQDFDLSQLHRGLDARPEVTRNDVAPTLMSVPRYLPRPANPDEIGNFIDENLKAADTDPTAPPYDSLLVFDYEGSGSEAASLSSLNSSESDKDQDYDYLNEWGNRFKKLADMYGGGEDD
Homo sapiens
Cell junction, adherens junction, Cell membrane, Endosome, Golgi apparatus, trans-Golgi network, Cytoplasm, Cell junction, desmosome
Tissue enhanced (parathyroid)
{'Ciliated cells': '119.1', 'Basal respiratory cells': '71.1', 'Club cells': '97.3', 'Ionocytes': '81.0', 'Mucus glandular cells': '155.0', 'Serous glandular cells': '67.8', 'Gastric mucus-secreting cells': '133.2', 'Proximal enterocytes': '140.9', 'Paneth cells': '125.1', 'Distal enterocytes': '307.5', 'Intestinal goblet cells': '173.5', 'Exocrine glandular cells': '-0.605', 'Basal prostatic cells': '68.3', 'Prostatic glandular cells': '186.7', 'Breast glandular cells': '0.773', 'Breast myoepithelial cells': '0.700', 'Glandular and luminal cells': '313.0', 'Secretory cells': '82.3', 'Basal keratinocytes': '102.5', 'Suprabasal keratinocytes': '162.6', 'Basal squamous epithelial cells': '51.0', 'Squamous epithelial cells': '106.9', 'Alveolar cells type 1': '0.437', 'Alveolar cells type 2': '0.706', 'Salivary duct cells': '95.9', 'Ductal cells': '0.541', 'Hepatocytes': '0.600', 'Cholangiocytes': '129.7', 'Proximal tubular cells': '0.042', 'Distal tubular cells': '0.0', 'Collecting duct cells': '143.9', 'Mesothelial cells': '0.799', 'Sertoli cells': '0.252', 'Granulosa cells': '12.9', 'Enteroendocrine cells': '92.4', 'Pancreatic endocrine cells': '78.1', 'Leydig cells': '0.264', 'Excitatory neurons': '0.7', 'Inhibitory neurons': '1.3', 'Cone photoreceptor cells': '0.0', 'Rod photoreceptor cells': '0.0', 'Bipolar cells': '0.2', 'Horizontal cells': '0.6', 'Astrocytes': '0.6', 'Oligodendrocyte precursor cells': '0.5', 'Oligodendrocytes': '29.9', 'Microglial cells': '0.9', 'Muller glia cells': '0.1', 'Schwann cells': '0.131', 'Spermatogonia': '0.392', 'Spermatocytes': '0.193', 'Early spermatids': '-0.217', 'Late spermatids': '-0.290', 'Oocytes': '16.9', 'Cytotrophoblasts': '119.2', 'Syncytiotrophoblasts': '45.0', 'Extravillous trophoblasts': '24.9', 'Endothelial cells': '6.1', 'Lymphatic endothelial cells': '0.4', 'Cardiomyocytes': '0.135', 'Skeletal myocytes': '0.107', 'Smooth muscle cells': '5.8', 'Adipocytes': '2.1', 'Melanocytes': '0.335', 'Fibroblasts': '6.5', 'Peritubular cells': '0.210', 'Endometrial stromal cells': '27.7', 'Ovarian stromal cells': '0.7', 'Undifferentiated cells': '101.6', 'T-cells': '2.9', 'B-cells': '4.4', 'Plasma cells': '6.1', 'Nk-cells': '0.0', 'Granulocytes': '8.4', 'Monocytes': '0.0', 'Macrophages': '6.0', 'Hofbauer cells': '4.3', 'Kupffer cells': '1.0', 'Dendritic cells': '5.9', 'Langerhans cells': '0.304', 'Erythroid cells': '0.036', 'Adipocytes (Subcutaneous)': '-0.081', 'Adipocytes (Visceral)': '-0.209', 'Breast glandular cells (progenitors)': '0.538', 'Adipocytes (Breast)': '-0.689', 'Colon enterocytes': '0.790', 'Colon enteroendocrine cells': '0.112', 'Enteric glia cells': '-0.048', 'Mitotic cells (Colon)': '0.299', 'Mitotic cells (Heart)': '0.120', 'Podocytes': '-0.118', 'Ascending Loop of Henle cells': '0.475', 'Intercalated cells': '0.212', 'Cholangiocyte': '0.090', 'NK-cells (Liver)': '-0.005', 'Respiratory ciliated cells': '-0.012', 'Mitotic cells (Lung)': '0.071', 'NK-cells (Lung)': '-0.266', 'B-cells (Lung)': '-0.296', 'Alpha cells': '0.270', 'Beta cells': '0.152', 'Prostate glandular cells': '0.764', 'Prostate basal glandular cells': '0.540', 'Urothelial cells': '0.205', 'Keratinocyte (other)': '0.510', 'Keratinocyte (granular)': '0.055', 'Hair cortex cells': '0.080', 'Inner root sheath cells': '0.131', 'Outer root sheath cells': '0.175', 'Sebaceous gland cells': '0.156', 'Eccrine sweat gland cells': '-0.207', 'Adipocytes (Skin)': '-0.244', 'Mitotic cells (Skin)': '0.442', 'Parietal cells': '0.654', 'Chief cells': '0.649', 'Gastric mucous cells': '0.781', 'Gastric enteroendocrine cells': '0.590', 'Mitotic cells (Stomach)': '0.445', 'Parafollicular cells': '0.173', 'Thyroid glandular cells': '0.865', 'Mitotic cells (Thyroid)': '-0.081', 'Adrenal cortex cells': '0.051', 'Adrenal medulla cells': '0.087', 'Mitotic cells (Adrenal gland)': '0.072', 'Minor salivary glandular cells': '0.371', 'Minor salivary gland ductal cells': '-0.142', 'Minor salivary gland basal cells': '0.582', 'Mitotic cells (Minor salivary gland)': '0.567', 'Adipocytes (Minor salivary gland)': '0.050', 'Somatotropes': '0.121', 'Lactotropes': '0.322', 'Gonadotropes': '0.330', 'Corticotropes': '0.180', 'Thyrotropes': '0.496', 'Undifferentiated cells (Pituitary gland)': '-0.108', 'Mitotic cells (Spleen)': '-0.228', 'Platelets': '-0.050', 'Erythrocytes': '-0.158', 'Hematopoietic stem cells': '-0.211', 'B-cells (Spleen)': '0.266', 'NK-cells (Spleen)': '0.309', 'Amygdala excitatory': '1.0', 'Cerebellar inhibitory': '0.9', 'Cge interneuron': '0.7', 'Deep-layer corticothalamic and 6b': '1.5', 'Deep-layer intratelencephalic': '0.7', 'Deep-layer near-projecting': '0.7', 'Eccentric medium spiny neuron': '0.6', 'Hippocampal ca1-3': '1.9', 'Hippocampal ca4': '1.2', 'Hippocampal dentate gyrus': '1.1', 'Lamp5-lhx6 and chandelier': '0.5', 'Lower rhombic lip': '0.8', 'Mammillary body': '0.6', 'Medium spiny neuron': '0.7', 'Mge interneuron': '1.7', 'Midbrain-derived inhibitory': '0.7', 'Miscellaneous': '0.9', 'Splatter': '3.8', 'Thalamic excitatory': '0.5', 'Upper rhombic lip': '0.8', 'Upper-layer intratelencephalic': '0.6', 'Astrocyte': '4.4', 'Bergmann glia': '0.2', 'Central nervous system macrophage': '0.6', 'Choroid plexus epithelial cell': '52.1', 'Committed oligodendrocyte precursor': '41.5', 'Ependymal cell': '4.8', 'Oligodendrocyte': '53.1', 'Oligodendrocyte precursor cell': '2.4', 'Endothelial cell': '0.7', 'Pericyte': '0.3', 'Vascular associated smooth muscle cell': '0.0', 'Fibroblast': '17.4', 'Leukocyte': '1.1', 'Basophil': '0.0', 'Eosinophil': '0.0', 'Neutrophil': '0.0', 'Classical monocyte': '0.0', 'Non-classical monocyte': '0.0', 'Intermediate monocyte': '0.0', 'T-reg': '2.3', 'GdT-cell': '0.0', 'MAIT T-cell': '0.0', 'Memory CD4 T-cell': '0.0', 'Naive CD4 T-cell': '0.1', 'Memory CD8 T-cell': '0.2', 'Naive CD8 T-cell': '0.3', 'Memory B-cell': '0.0', 'Naive B-cell': '0.1', 'Plasmacytoid DC': '46.6', 'Myeloid DC': '8.5', 'NK-cell': '0.1', 'Total PBMC': '0.7', 'Vd2 gdTCR': '0.0', 'Memory CD4 T-cell Th1\\/Th17': '0.1', 'Memory CD4 T-cell Th17': '0.2', 'Memory CD4 T-cell Th2': '2.9', 'Non-Vd2 gdTCR': '0.1', 'Memory CD4 T-cell Th1': '0.3', 'Memory CD4 T-cell TFH': '0.5', 'Terminal effector memory CD4 T-cell': '0.0', 'Central memory CD8 T-cell': '4.8', 'Effector memory CD8 T-cell': '0.0', 'Terminal effector memory CD8 T-cell': '0.6', 'Non-switched memory B-cell': '0.0', 'Plasmablast': '3.3', 'Switched memory B-cell': '0.0', 'Exhausted memory B-cell': '0.7', 'Progenitor cell': '2.3', 'Memory T-reg': '1.3', 'Naive CD4 T-cell activated': '0.3', 'Naive CD8 T-cell activated': '0.6', 'Naive T-reg': '0.1'}
1O6S, 2O72, 2OMT, 2OMU, 2OMV, 2OMX, 2OMY, 2OMZ, 3FF7, 3FF8, 3L6X, 3L6Y, 4ZT1, 4ZTE, 6CXY, 6OLE, 6OLF, 6OLG, 6VEL, 7STZ, 8H62
{'Adipose Tissue': 1.2125261088039867, 'Adrenal Gland': 0.1914223992248062, 'Bladder': 39.2033519047619, 'Blood': 1.340954264800861, 'Blood Vessel': 0.3121561692883895, 'Brain': 0.8550442199091597, 'Breast': 38.54918344226579, 'Cervix Uteri': 23.539115789473684, 'Colon': 43.41292142490372, 'Esophagus': 53.97513367404844, 'Fallopian Tube': 14.900277777777776, 'Heart': 0.119140469221835, 'Kidney': 25.040449438202245, 'Liver': 26.60802654867257, 'Lung': 35.447986366782004, 'Muscle': 0.1378936151930261, 'Nerve': 17.518468982229404, 'Ovary': 3.6515122222222223, 'Pancreas': 56.89676829268293, 'Pituitary': 24.68741660777385, 'Prostate': 61.279967346938776, 'Salivary Gland': 92.01685185185184, 'Skin': 79.77571720232172, 'Small Intestine': 71.7519320855615, 'Spleen': 10.061029045643156, 'Stomach': 58.07813805013927, 'Testis': 0.8144204986149585, 'Thyroid': 135.176797856049, 'Uterus': 1.442593943661972, 'Vagina': 86.52345512820513}
KIF22
MAAGGSTQQRRREMAAASAAAISGAGRCRLSKIGATRRPPPARVRVAVRLRPFVDGTAGASDPPCVRGMDSCSLEIANWRNHQETLKYQFDAFYGERSTQQDIYAGSVQPILRHLLEGQNASVLAYGPTGAGKTHTMLGSPEQPGVIPRALMDLLQLTREEGAEGRPWALSVTMSYLEIYQEKVLDLLDPASGDLVIREDCRGNILIPGLSQKPISSFADFERHFLPASRNRTVGATRLNQRSSRSHAVLLVKVDQRERLAPFRQREGKLYLIDLAGSEDNRRTGNKGLRLKESGAINTSLFVLGKVVDALNQGLPRVPYRDSKLTRLLQDSLGGSAHSILIANIAPERRFYLDTVSALNFAARSKEVINRPFTNESLQPHALGPVKLSQKELLGPPEAKRARGPEEEEIGSPEPMAAPASASQKLSPLQKLSSMDPAMLERLLSLDRLLASQGSQGAPLLSTPKRERMVLMKTVEEKDLEIERLKTKQKELEAKMLAQKAEEKENHCPTMLRPLSHRTVTGAKPLKKAVVMPLQLIQEQAASPNAEIHILKNKGRKRKLESLDALEPEEKAEDCWELQISPELLAHGRQKILDLLNEGSARDLRSLQRIGPKKAQLIVGWRELHGPFSQVEDLERVEGITGKQMESFLKANILGLAAGQRCGAS
Homo sapiens
Nucleus, Cytoplasm, cytoskeleton
Tissue enhanced (lymphoid)
{'Ciliated cells': '24.3', 'Basal respiratory cells': '52.8', 'Club cells': '30.3', 'Ionocytes': '32.0', 'Mucus glandular cells': '11.6', 'Serous glandular cells': '21.2', 'Gastric mucus-secreting cells': '24.8', 'Proximal enterocytes': '12.4', 'Paneth cells': '48.7', 'Distal enterocytes': '56.0', 'Intestinal goblet cells': '39.4', 'Exocrine glandular cells': '-0.590', 'Basal prostatic cells': '77.5', 'Prostatic glandular cells': '57.7', 'Breast glandular cells': '0.713', 'Breast myoepithelial cells': '0.686', 'Glandular and luminal cells': '33.1', 'Secretory cells': '32.7', 'Basal keratinocytes': '29.2', 'Suprabasal keratinocytes': '24.6', 'Basal squamous epithelial cells': '45.7', 'Squamous epithelial cells': '38.1', 'Alveolar cells type 1': '-0.018', 'Alveolar cells type 2': '0.018', 'Salivary duct cells': '13.7', 'Ductal cells': '0.422', 'Hepatocytes': '0.481', 'Cholangiocytes': '49.6', 'Proximal tubular cells': '0.134', 'Distal tubular cells': '64.5', 'Collecting duct cells': '62.2', 'Mesothelial cells': '0.413', 'Sertoli cells': '0.231', 'Granulosa cells': '22.9', 'Enteroendocrine cells': '40.4', 'Pancreatic endocrine cells': '27.2', 'Leydig cells': '0.092', 'Excitatory neurons': '4.6', 'Inhibitory neurons': '5.9', 'Cone photoreceptor cells': '20.4', 'Rod photoreceptor cells': '20.8', 'Bipolar cells': '24.2', 'Horizontal cells': '15.1', 'Astrocytes': '5.3', 'Oligodendrocyte precursor cells': '3.8', 'Oligodendrocytes': '4.9', 'Microglial cells': '4.5', 'Muller glia cells': '72.3', 'Schwann cells': '0.202', 'Spermatogonia': '0.462', 'Spermatocytes': '0.579', 'Early spermatids': '0.117', 'Late spermatids': '-0.158', 'Oocytes': '96.3', 'Cytotrophoblasts': '82.6', 'Syncytiotrophoblasts': '87.8', 'Extravillous trophoblasts': '88.9', 'Endothelial cells': '23.9', 'Lymphatic endothelial cells': '19.8', 'Cardiomyocytes': '0.597', 'Skeletal myocytes': '0.371', 'Smooth muscle cells': '30.7', 'Adipocytes': '16.5', 'Melanocytes': '0.432', 'Fibroblasts': '45.0', 'Peritubular cells': '0.044', 'Endometrial stromal cells': '18.7', 'Ovarian stromal cells': '50.5', 'Undifferentiated cells': '53.5', 'T-cells': '29.5', 'B-cells': '21.3', 'Plasma cells': '52.2', 'Nk-cells': '25.2', 'Granulocytes': '32.1', 'Monocytes': '25.6', 'Macrophages': '30.8', 'Hofbauer cells': '47.9', 'Kupffer cells': '44.6', 'Dendritic cells': '9.3', 'Langerhans cells': '0.373', 'Erythroid cells': '0.072', 'Adipocytes (Subcutaneous)': '-0.232', 'Adipocytes (Visceral)': '-0.219', 'Breast glandular cells (progenitors)': '0.569', 'Adipocytes (Breast)': '-0.652', 'Colon enterocytes': '0.268', 'Colon enteroendocrine cells': '0.049', 'Enteric glia cells': '-0.059', 'Mitotic cells (Colon)': '0.202', 'Mitotic cells (Heart)': '0.303', 'Podocytes': '-0.143', 'Ascending Loop of Henle cells': '0.543', 'Intercalated cells': '0.047', 'Cholangiocyte': '0.072', 'NK-cells (Liver)': '0.127', 'Respiratory ciliated cells': '0.188', 'Mitotic cells (Lung)': '0.450', 'NK-cells (Lung)': '0.101', 'B-cells (Lung)': '0.110', 'Alpha cells': '0.292', 'Beta cells': '0.217', 'Prostate glandular cells': '0.431', 'Prostate basal glandular cells': '0.423', 'Urothelial cells': '0.241', 'Keratinocyte (other)': '0.669', 'Keratinocyte (granular)': '-0.042', 'Hair cortex cells': '-0.171', 'Inner root sheath cells': '-0.065', 'Outer root sheath cells': '0.006', 'Sebaceous gland cells': '-0.091', 'Eccrine sweat gland cells': '-0.339', 'Adipocytes (Skin)': '-0.494', 'Mitotic cells (Skin)': '0.551', 'Parietal cells': '-0.109', 'Chief cells': '-0.055', 'Gastric mucous cells': '0.288', 'Gastric enteroendocrine cells': '0.067', 'Mitotic cells (Stomach)': '0.620', 'Parafollicular cells': '0.137', 'Thyroid glandular cells': '0.409', 'Mitotic cells (Thyroid)': '-0.016', 'Adrenal cortex cells': '0.294', 'Adrenal medulla cells': '0.086', 'Mitotic cells (Adrenal gland)': '0.396', 'Minor salivary glandular cells': '0.203', 'Minor salivary gland ductal cells': '-0.112', 'Minor salivary gland basal cells': '0.705', 'Mitotic cells (Minor salivary gland)': '0.724', 'Adipocytes (Minor salivary gland)': '0.299', 'Somatotropes': '-0.128', 'Lactotropes': '0.014', 'Gonadotropes': '0.140', 'Corticotropes': '0.088', 'Thyrotropes': '0.191', 'Undifferentiated cells (Pituitary gland)': '0.270', 'Mitotic cells (Spleen)': '0.585', 'Platelets': '-0.052', 'Erythrocytes': '0.215', 'Hematopoietic stem cells': '0.066', 'B-cells (Spleen)': '0.238', 'NK-cells (Spleen)': '0.094', 'Amygdala excitatory': '10.1', 'Cerebellar inhibitory': '11.5', 'Cge interneuron': '15.8', 'Deep-layer corticothalamic and 6b': '10.9', 'Deep-layer intratelencephalic': '10.0', 'Deep-layer near-projecting': '12.1', 'Eccentric medium spiny neuron': '13.1', 'Hippocampal ca1-3': '9.3', 'Hippocampal ca4': '12.2', 'Hippocampal dentate gyrus': '11.6', 'Lamp5-lhx6 and chandelier': '14.4', 'Lower rhombic lip': '16.5', 'Mammillary body': '18.6', 'Medium spiny neuron': '12.5', 'Mge interneuron': '13.9', 'Midbrain-derived inhibitory': '30.5', 'Miscellaneous': '9.7', 'Splatter': '15.9', 'Thalamic excitatory': '11.6', 'Upper rhombic lip': '19.6', 'Upper-layer intratelencephalic': '10.3', 'Astrocyte': '21.2', 'Bergmann glia': '18.4', 'Central nervous system macrophage': '11.3', 'Choroid plexus epithelial cell': '11.5', 'Committed oligodendrocyte precursor': '12.5', 'Ependymal cell': '17.5', 'Oligodendrocyte': '12.6', 'Oligodendrocyte precursor cell': '12.4', 'Endothelial cell': '9.6', 'Pericyte': '16.0', 'Vascular associated smooth muscle cell': '19.8', 'Fibroblast': '26.4', 'Leukocyte': '22.5', 'Basophil': '24.3', 'Eosinophil': '32.5', 'Neutrophil': '9.5', 'Classical monocyte': '10.1', 'Non-classical monocyte': '17.0', 'Intermediate monocyte': '29.7', 'T-reg': '49.2', 'GdT-cell': '39.9', 'MAIT T-cell': '39.7', 'Memory CD4 T-cell': '43.3', 'Naive CD4 T-cell': '50.4', 'Memory CD8 T-cell': '46.6', 'Naive CD8 T-cell': '51.5', 'Memory B-cell': '24.2', 'Naive B-cell': '21.5', 'Plasmacytoid DC': '16.4', 'Myeloid DC': '15.7', 'NK-cell': '53.8', 'Total PBMC': '27.4', 'Vd2 gdTCR': '36.6', 'Memory CD4 T-cell Th1\\/Th17': '54.3', 'Memory CD4 T-cell Th17': '70.4', 'Memory CD4 T-cell Th2': '73.9', 'Non-Vd2 gdTCR': '49.1', 'Memory CD4 T-cell Th1': '77.3', 'Memory CD4 T-cell TFH': '93.6', 'Terminal effector memory CD4 T-cell': '66.9', 'Central memory CD8 T-cell': '41.0', 'Effector memory CD8 T-cell': '55.9', 'Terminal effector memory CD8 T-cell': '46.1', 'Non-switched memory B-cell': '28.4', 'Plasmablast': '72.0', 'Switched memory B-cell': '35.5', 'Exhausted memory B-cell': '36.5', 'Progenitor cell': '25.7', 'Memory T-reg': '95.0', 'Naive CD4 T-cell activated': '18.2', 'Naive CD8 T-cell activated': '24.2', 'Naive T-reg': '54.0'}
2EDU, 6NJE
{'Adipose Tissue': 11.376390365448504, 'Adrenal Gland': 8.589713178294573, 'Bladder': 15.476714285714287, 'Blood': 24.7057345532831, 'Blood Vessel': 14.226916104868916, 'Brain': 9.7878315669947, 'Breast': 17.74922440087146, 'Cervix Uteri': 15.907368421052633, 'Colon': 16.801667522464697, 'Esophagus': 15.742590311418686, 'Fallopian Tube': 15.530555555555557, 'Heart': 7.62959430894309, 'Kidney': 10.838808988764043, 'Liver': 6.996243805309735, 'Lung': 14.977318339100345, 'Muscle': 5.569960149439601, 'Nerve': 18.755242326332795, 'Ovary': 14.971027777777778, 'Pancreas': 4.727390243902439, 'Pituitary': 15.806335689045936, 'Prostate': 28.59808163265306, 'Salivary Gland': 13.21441975308642, 'Skin': 35.30904422332781, 'Small Intestine': 22.425716577540108, 'Spleen': 25.16746887966805, 'Stomach': 11.133189415041782, 'Testis': 51.964847645429366, 'Thyroid': 48.54188055130169, 'Uterus': 15.22199295774648, 'Vagina': 20.119153846153846}
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[39.33, 40.08, 41.25, 39.59, 39.42, 44.25, 46.26, 46.7, 45.19, 47.52, 49.05, 47.2, 45.82, 43.6, 45.06, 40.82, 40.61, 42.36, 42.11, 38.66, 37.58, 47.31, 43.68, 33.66, 38.28, 31.74, 40.75, 32.69, 39.05, 40.04, 39.27, 35.69, 39.69, 36.26, 35.54, 53.23, 59.82, 69.23, 77.79, 87.09, 90.66, 92.8, 94.84, 96.42, 97.2, 97.86, 98.07, 98.3, 97.83, 97.25, 94.64, 92.71, 89.61, 85.07, 64.34, 58.47, 54.3, 43.46, 46.6, 54.05, 61.57, 70.14, 78.9, 86.98, 88.83, 92.29, 90.03, 91.39, 91.07, 92.25, 93.41, 94.34, 93.28, 94.57, 92.48, 91.8, 85.0, 83.33, 77.06, 77.61, 77.23, 71.11, 70.25, 80.85, 84.87, 89.53, 92.51, 95.4, 95.79, 97.23, 96.97, 97.36, 97.68, 97.29, 94.76, 92.65, 93.33, 94.78, 95.7, 96.34, 96.24, 96.21, 96.74, 97.9, 96.82, 94.84, 96.03, 97.25, 96.45, 94.86, 94.88, 95.44, 92.92, 93.78, 93.93, 91.42, 90.69, 91.81, 93.55, 94.62, 96.22, 96.83, 98.06, 97.68, 97.71, 97.02, 95.26, 92.02, 89.92, 88.44, 92.6, 93.34, 95.31, 92.99, 94.13, 97.05, 96.41, 93.18, 91.28, 88.72, 85.23, 89.45, 90.03, 93.7, 96.22, 97.73, 96.87, 95.43, 96.79, 97.1, 95.88, 94.65, 95.41, 95.47, 94.63, 93.68, 92.38, 91.47, 90.09, 88.58, 85.74, 81.51, 80.09, 65.71, 71.47, 78.85, 83.17, 85.9, 89.71, 92.57, 93.9, 96.81, 97.2, 97.28, 96.74, 96.11, 94.49, 93.13, 92.92, 88.92, 87.3, 90.62, 91.49, 93.55, 92.52, 94.4, 92.76, 93.39, 91.36, 82.95, 83.53, 75.38, 85.52, 92.99, 94.11, 93.63, 93.4, 92.05, 87.97, 84.3, 83.17, 76.82, 77.23, 82.02, 87.38, 89.15, 93.1, 92.05, 92.1, 94.79, 95.73, 95.44, 96.22, 96.32, 96.2, 92.21, 94.08, 93.28, 94.35, 94.73, 94.86, 92.28, 95.06, 94.64, 93.12, 89.71, 90.87, 90.93, 87.03, 82.96, 80.32, 80.58, 61.48, 57.21, 57.66, 56.48, 49.4, 50.98, 49.29, 54.34, 63.0, 69.82, 74.7, 78.53, 82.66, 89.43, 93.17, 94.08, 95.64, 96.76, 96.01, 96.66, 95.32, 95.6, 94.12, 92.75, 92.05, 88.66, 84.26, 82.94, 80.76, 85.34, 86.17, 89.41, 90.68, 91.58, 92.57, 93.48, 94.62, 96.49, 96.45, 97.51, 96.81, 95.66, 95.05, 92.76, 91.21, 91.73, 86.01, 79.28, 73.52, 68.6, 69.97, 69.09, 69.82, 73.59, 78.37, 81.94, 80.19, 79.13, 82.46, 84.47, 82.39, 83.61, 85.96, 88.41, 87.09, 89.01, 91.95, 93.62, 93.37, 94.15, 96.07, 96.34, 96.06, 96.92, 97.29, 96.77, 96.46, 97.09, 96.07, 95.94, 94.89, 92.58, 93.72, 90.3, 93.11, 94.69, 95.58, 94.93, 94.34, 94.57, 94.8, 94.37, 94.25, 95.17, 94.12, 93.08, 92.47, 92.43, 87.53, 91.25, 92.39, 89.25, 89.89, 91.11, 93.28, 95.78, 96.92, 97.7, 98.08, 98.38, 98.14, 97.98, 96.79, 93.77, 92.9, 90.04, 87.73, 86.03, 89.04, 91.03, 90.7, 92.09, 93.65, 93.38, 93.7, 95.59, 96.53, 95.72, 96.42, 97.12, 96.56, 96.41, 96.69, 96.0, 95.35, 95.78, 95.49, 94.34, 92.89, 90.54, 88.02, 88.6, 85.05, 84.97, 85.47, 82.26, 67.85, 58.62, 53.21, 43.08, 39.07, 37.22, 36.67, 38.1, 38.61, 38.56, 35.13, 42.98, 40.05, 36.38, 42.47, 44.74, 36.36, 45.92, 45.13, 41.08, 43.81, 45.51, 41.28, 43.49, 40.19, 41.84, 42.97, 34.62, 41.31, 34.62, 38.16, 37.64, 35.63, 38.96, 39.95, 34.97, 36.17, 39.22, 32.13, 35.9, 37.52, 32.2, 34.14, 31.69, 31.23, 31.61, 35.14, 29.93, 36.49, 37.77, 28.24, 35.58, 35.64, 39.72, 45.84, 52.16, 50.76, 70.47, 67.66, 69.62, 59.6, 66.41, 68.4, 67.48, 62.4, 69.26, 71.09, 64.97, 60.36, 69.02, 63.71, 59.16, 56.29, 59.24, 46.54, 38.91, 42.88, 38.98, 42.29, 49.91, 45.66, 50.25, 53.36, 51.72, 57.55, 67.21, 61.23, 70.59, 63.08, 67.75, 68.75, 76.43, 70.31, 71.54, 80.67, 79.27, 78.08, 80.01, 83.22, 80.46, 84.66, 89.25, 85.81, 84.03, 86.83, 90.02, 85.03, 87.52, 88.33, 88.35, 84.81, 86.66, 86.93, 84.63, 84.14, 84.52, 85.73, 81.94, 80.05, 79.49, 75.72, 72.2, 67.21, 61.39, 57.86, 52.85, 48.88, 43.9, 37.9, 30.77, 34.54, 34.79, 31.59, 36.8, 35.28, 33.75, 35.6, 31.94, 31.88, 31.97, 29.32, 36.25, 36.35, 30.69, 35.77, 38.52, 37.48, 43.07, 41.69, 57.65, 58.87, 69.09, 66.69, 51.8, 47.94, 44.26, 47.12, 34.89, 34.16, 30.77, 30.53, 30.79, 30.58, 28.11, 30.32, 31.11, 29.41, 33.52, 29.0, 30.91, 28.98, 33.62, 30.46, 29.28, 32.32, 30.17, 29.33, 34.2, 37.08, 29.02, 32.92, 31.04, 35.23, 34.5, 33.61, 32.21, 35.47, 33.65, 34.84, 35.73, 33.76, 36.79, 33.12, 33.98, 35.39, 30.68, 27.31, 31.09, 28.33, 34.71, 41.92, 58.27, 68.33, 76.97, 76.78, 73.79, 78.39, 82.22, 83.03, 84.1, 89.91, 89.26, 88.74, 91.42, 92.84, 91.3, 91.58, 92.59, 92.76, 90.29, 88.42, 91.14, 90.17, 89.92, 89.48, 90.94, 89.26, 87.35, 88.24, 86.19, 86.57, 88.03, 87.68, 89.81, 90.31, 91.46, 92.84, 92.24, 92.69, 92.68, 92.58, 92.03, 93.52, 92.42, 90.36, 90.13, 90.87, 90.36, 91.36, 92.62, 90.96, 91.7, 89.96, 90.77, 90.87, 89.82, 90.28, 88.26, 89.57, 84.58, 83.33, 86.19, 86.9, 83.83, 83.83, 86.02, 88.73, 85.4, 84.99, 89.04, 86.64, 83.13, 84.02, 85.97, 81.54, 73.17, 72.41, 69.92, 65.51, 56.97, 53.25, 40.34, 34.5, 30.08, 29.91, 29.11, 30.58]
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null
Component of an E-cadherin/ catenin adhesion complex composed of at least E-cadherin/CDH1, beta-catenin/CTNNB1 or gamma-catenin/JUP, and potentially alpha-catenin/CTNNA1. Forms a ternary complex composed of ADAM10, CADH1 and EPHA4,
null
null
KLRG1, SPEF1, DLGAP5, AJAP1, RAPGEF2, RAB8B, PIP5K1C, PKP2, TRPV4, CTNNB1, CAV1, DDR1, TBC1D2, CTNNA1, JUP, CTNND1, PSEN1, LIMA1, CDH1, JUP, ADAM10, CADH1 , EPHA4,
null
null
null
null
Homodimer
null
79.91949
0.474025
73.433925
0.492977
1,093
P12830
Q15004
null
degron_data
CDH1
MGPWSRSLSALLLLLQVSSWLCQEPEPCHPGFDAESYTFTVPRRHLERGRVLGRVNFEDCTGRQRTAYFSLDTRFKVGTDGVITVKRPLRFHNPQIHFLVYAWDSTYRKFSTKVTLNTVGHHHRPPPHQASVSGIQAELLTFPNSSPGLRRQKRDWVIPPISCPENEKGPFPKNLVQIKSNKDKEGKVFYSITGQGADTPPVGVFIIERETGWLKVTEPLDRERIATYTLFSHAVSSNGNAVEDPMEILITVTDQNDNKPEFTQEVFKGSVMEGALPGTSVMEVTATDADDDVNTYNAAIAYTILSQDPELPDKNMFTINRNTGVISVVTTGLDRESFPTYTLVVQAADLQGEGLSTTATAVITVTDTNDNPPIFNPTTYKGQVPENEANVVITTLKVTDADAPNTPAWEAVYTILNDDGGQFVVTTNPVNNDGILKTAKGLDFEAKQQYILHVAVTNVVPFEVSLTTSTATVTVDVLDVNEAPIFVPPEKRVEVSEDFGVGQEITSYTAQEPDTFMEQKITYRIWRDTANWLEINPDTGAISTRAELDREDFEHVKNSTYTALIIATDNGSPVATGTGTLLLILSDVNDNAPIPEPRTIFFCERNPKPQVINIIDADLPPNTSPFTAELTHGASANWTIQYNDPTQESIILKPKMALEVGDYKINLKLMDNQNKDQVTTLEVSVCDCEGAAGVCRKAQPVEAGLQIPAILGILGGILALLILILLLLLFLRRRAVVKEPLLPPEDDTRDNVYYYDEEGGGEEDQDFDLSQLHRGLDARPEVTRNDVAPTLMSVPRYLPRPANPDEIGNFIDENLKAADTDPTAPPYDSLLVFDYEGSGSEAASLSSLNSSESDKDQDYDYLNEWGNRFKKLADMYGGGEDD
Homo sapiens
Cell junction, adherens junction, Cell membrane, Endosome, Golgi apparatus, trans-Golgi network, Cytoplasm, Cell junction, desmosome
Tissue enhanced (parathyroid)
{'Ciliated cells': '119.1', 'Basal respiratory cells': '71.1', 'Club cells': '97.3', 'Ionocytes': '81.0', 'Mucus glandular cells': '155.0', 'Serous glandular cells': '67.8', 'Gastric mucus-secreting cells': '133.2', 'Proximal enterocytes': '140.9', 'Paneth cells': '125.1', 'Distal enterocytes': '307.5', 'Intestinal goblet cells': '173.5', 'Exocrine glandular cells': '-0.605', 'Basal prostatic cells': '68.3', 'Prostatic glandular cells': '186.7', 'Breast glandular cells': '0.773', 'Breast myoepithelial cells': '0.700', 'Glandular and luminal cells': '313.0', 'Secretory cells': '82.3', 'Basal keratinocytes': '102.5', 'Suprabasal keratinocytes': '162.6', 'Basal squamous epithelial cells': '51.0', 'Squamous epithelial cells': '106.9', 'Alveolar cells type 1': '0.437', 'Alveolar cells type 2': '0.706', 'Salivary duct cells': '95.9', 'Ductal cells': '0.541', 'Hepatocytes': '0.600', 'Cholangiocytes': '129.7', 'Proximal tubular cells': '0.042', 'Distal tubular cells': '0.0', 'Collecting duct cells': '143.9', 'Mesothelial cells': '0.799', 'Sertoli cells': '0.252', 'Granulosa cells': '12.9', 'Enteroendocrine cells': '92.4', 'Pancreatic endocrine cells': '78.1', 'Leydig cells': '0.264', 'Excitatory neurons': '0.7', 'Inhibitory neurons': '1.3', 'Cone photoreceptor cells': '0.0', 'Rod photoreceptor cells': '0.0', 'Bipolar cells': '0.2', 'Horizontal cells': '0.6', 'Astrocytes': '0.6', 'Oligodendrocyte precursor cells': '0.5', 'Oligodendrocytes': '29.9', 'Microglial cells': '0.9', 'Muller glia cells': '0.1', 'Schwann cells': '0.131', 'Spermatogonia': '0.392', 'Spermatocytes': '0.193', 'Early spermatids': '-0.217', 'Late spermatids': '-0.290', 'Oocytes': '16.9', 'Cytotrophoblasts': '119.2', 'Syncytiotrophoblasts': '45.0', 'Extravillous trophoblasts': '24.9', 'Endothelial cells': '6.1', 'Lymphatic endothelial cells': '0.4', 'Cardiomyocytes': '0.135', 'Skeletal myocytes': '0.107', 'Smooth muscle cells': '5.8', 'Adipocytes': '2.1', 'Melanocytes': '0.335', 'Fibroblasts': '6.5', 'Peritubular cells': '0.210', 'Endometrial stromal cells': '27.7', 'Ovarian stromal cells': '0.7', 'Undifferentiated cells': '101.6', 'T-cells': '2.9', 'B-cells': '4.4', 'Plasma cells': '6.1', 'Nk-cells': '0.0', 'Granulocytes': '8.4', 'Monocytes': '0.0', 'Macrophages': '6.0', 'Hofbauer cells': '4.3', 'Kupffer cells': '1.0', 'Dendritic cells': '5.9', 'Langerhans cells': '0.304', 'Erythroid cells': '0.036', 'Adipocytes (Subcutaneous)': '-0.081', 'Adipocytes (Visceral)': '-0.209', 'Breast glandular cells (progenitors)': '0.538', 'Adipocytes (Breast)': '-0.689', 'Colon enterocytes': '0.790', 'Colon enteroendocrine cells': '0.112', 'Enteric glia cells': '-0.048', 'Mitotic cells (Colon)': '0.299', 'Mitotic cells (Heart)': '0.120', 'Podocytes': '-0.118', 'Ascending Loop of Henle cells': '0.475', 'Intercalated cells': '0.212', 'Cholangiocyte': '0.090', 'NK-cells (Liver)': '-0.005', 'Respiratory ciliated cells': '-0.012', 'Mitotic cells (Lung)': '0.071', 'NK-cells (Lung)': '-0.266', 'B-cells (Lung)': '-0.296', 'Alpha cells': '0.270', 'Beta cells': '0.152', 'Prostate glandular cells': '0.764', 'Prostate basal glandular cells': '0.540', 'Urothelial cells': '0.205', 'Keratinocyte (other)': '0.510', 'Keratinocyte (granular)': '0.055', 'Hair cortex cells': '0.080', 'Inner root sheath cells': '0.131', 'Outer root sheath cells': '0.175', 'Sebaceous gland cells': '0.156', 'Eccrine sweat gland cells': '-0.207', 'Adipocytes (Skin)': '-0.244', 'Mitotic cells (Skin)': '0.442', 'Parietal cells': '0.654', 'Chief cells': '0.649', 'Gastric mucous cells': '0.781', 'Gastric enteroendocrine cells': '0.590', 'Mitotic cells (Stomach)': '0.445', 'Parafollicular cells': '0.173', 'Thyroid glandular cells': '0.865', 'Mitotic cells (Thyroid)': '-0.081', 'Adrenal cortex cells': '0.051', 'Adrenal medulla cells': '0.087', 'Mitotic cells (Adrenal gland)': '0.072', 'Minor salivary glandular cells': '0.371', 'Minor salivary gland ductal cells': '-0.142', 'Minor salivary gland basal cells': '0.582', 'Mitotic cells (Minor salivary gland)': '0.567', 'Adipocytes (Minor salivary gland)': '0.050', 'Somatotropes': '0.121', 'Lactotropes': '0.322', 'Gonadotropes': '0.330', 'Corticotropes': '0.180', 'Thyrotropes': '0.496', 'Undifferentiated cells (Pituitary gland)': '-0.108', 'Mitotic cells (Spleen)': '-0.228', 'Platelets': '-0.050', 'Erythrocytes': '-0.158', 'Hematopoietic stem cells': '-0.211', 'B-cells (Spleen)': '0.266', 'NK-cells (Spleen)': '0.309', 'Amygdala excitatory': '1.0', 'Cerebellar inhibitory': '0.9', 'Cge interneuron': '0.7', 'Deep-layer corticothalamic and 6b': '1.5', 'Deep-layer intratelencephalic': '0.7', 'Deep-layer near-projecting': '0.7', 'Eccentric medium spiny neuron': '0.6', 'Hippocampal ca1-3': '1.9', 'Hippocampal ca4': '1.2', 'Hippocampal dentate gyrus': '1.1', 'Lamp5-lhx6 and chandelier': '0.5', 'Lower rhombic lip': '0.8', 'Mammillary body': '0.6', 'Medium spiny neuron': '0.7', 'Mge interneuron': '1.7', 'Midbrain-derived inhibitory': '0.7', 'Miscellaneous': '0.9', 'Splatter': '3.8', 'Thalamic excitatory': '0.5', 'Upper rhombic lip': '0.8', 'Upper-layer intratelencephalic': '0.6', 'Astrocyte': '4.4', 'Bergmann glia': '0.2', 'Central nervous system macrophage': '0.6', 'Choroid plexus epithelial cell': '52.1', 'Committed oligodendrocyte precursor': '41.5', 'Ependymal cell': '4.8', 'Oligodendrocyte': '53.1', 'Oligodendrocyte precursor cell': '2.4', 'Endothelial cell': '0.7', 'Pericyte': '0.3', 'Vascular associated smooth muscle cell': '0.0', 'Fibroblast': '17.4', 'Leukocyte': '1.1', 'Basophil': '0.0', 'Eosinophil': '0.0', 'Neutrophil': '0.0', 'Classical monocyte': '0.0', 'Non-classical monocyte': '0.0', 'Intermediate monocyte': '0.0', 'T-reg': '2.3', 'GdT-cell': '0.0', 'MAIT T-cell': '0.0', 'Memory CD4 T-cell': '0.0', 'Naive CD4 T-cell': '0.1', 'Memory CD8 T-cell': '0.2', 'Naive CD8 T-cell': '0.3', 'Memory B-cell': '0.0', 'Naive B-cell': '0.1', 'Plasmacytoid DC': '46.6', 'Myeloid DC': '8.5', 'NK-cell': '0.1', 'Total PBMC': '0.7', 'Vd2 gdTCR': '0.0', 'Memory CD4 T-cell Th1\\/Th17': '0.1', 'Memory CD4 T-cell Th17': '0.2', 'Memory CD4 T-cell Th2': '2.9', 'Non-Vd2 gdTCR': '0.1', 'Memory CD4 T-cell Th1': '0.3', 'Memory CD4 T-cell TFH': '0.5', 'Terminal effector memory CD4 T-cell': '0.0', 'Central memory CD8 T-cell': '4.8', 'Effector memory CD8 T-cell': '0.0', 'Terminal effector memory CD8 T-cell': '0.6', 'Non-switched memory B-cell': '0.0', 'Plasmablast': '3.3', 'Switched memory B-cell': '0.0', 'Exhausted memory B-cell': '0.7', 'Progenitor cell': '2.3', 'Memory T-reg': '1.3', 'Naive CD4 T-cell activated': '0.3', 'Naive CD8 T-cell activated': '0.6', 'Naive T-reg': '0.1'}
1O6S, 2O72, 2OMT, 2OMU, 2OMV, 2OMX, 2OMY, 2OMZ, 3FF7, 3FF8, 3L6X, 3L6Y, 4ZT1, 4ZTE, 6CXY, 6OLE, 6OLF, 6OLG, 6VEL, 7STZ, 8H62
{'Adipose Tissue': 1.2125261088039867, 'Adrenal Gland': 0.1914223992248062, 'Bladder': 39.2033519047619, 'Blood': 1.340954264800861, 'Blood Vessel': 0.3121561692883895, 'Brain': 0.8550442199091597, 'Breast': 38.54918344226579, 'Cervix Uteri': 23.539115789473684, 'Colon': 43.41292142490372, 'Esophagus': 53.97513367404844, 'Fallopian Tube': 14.900277777777776, 'Heart': 0.119140469221835, 'Kidney': 25.040449438202245, 'Liver': 26.60802654867257, 'Lung': 35.447986366782004, 'Muscle': 0.1378936151930261, 'Nerve': 17.518468982229404, 'Ovary': 3.6515122222222223, 'Pancreas': 56.89676829268293, 'Pituitary': 24.68741660777385, 'Prostate': 61.279967346938776, 'Salivary Gland': 92.01685185185184, 'Skin': 79.77571720232172, 'Small Intestine': 71.7519320855615, 'Spleen': 10.061029045643156, 'Stomach': 58.07813805013927, 'Testis': 0.8144204986149585, 'Thyroid': 135.176797856049, 'Uterus': 1.442593943661972, 'Vagina': 86.52345512820513}
PCLAF
MVRTKADSVPGTYRKVVAARAPRKVLGSSTSATNSTSVSSRKAENKYAGGNPVCVRPTPKWQKGIGEFFRLSPKDSEKENQIPEEAGSSGLGKAKRKACPLQPDHTNDEKE
Homo sapiens
Nucleus, Cytoplasm, perinuclear region
Group enriched (bone marrow, lymphoid tissue)
{'Ciliated cells': '7.3', 'Basal respiratory cells': '39.7', 'Club cells': '10.3', 'Ionocytes': '7.0', 'Mucus glandular cells': '1.6', 'Serous glandular cells': '18.8', 'Gastric mucus-secreting cells': '15.3', 'Proximal enterocytes': '7.2', 'Paneth cells': '4.8', 'Distal enterocytes': '6.4', 'Intestinal goblet cells': '41.1', 'Exocrine glandular cells': '-0.242', 'Basal prostatic cells': '0.8', 'Prostatic glandular cells': '2.2', 'Breast glandular cells': '0.293', 'Breast myoepithelial cells': '0.274', 'Glandular and luminal cells': '14.7', 'Secretory cells': '2.4', 'Basal keratinocytes': '54.7', 'Suprabasal keratinocytes': '20.5', 'Basal squamous epithelial cells': '14.2', 'Squamous epithelial cells': '32.5', 'Alveolar cells type 1': '-0.207', 'Alveolar cells type 2': '0.224', 'Salivary duct cells': '5.5', 'Ductal cells': '0.405', 'Hepatocytes': '0.376', 'Cholangiocytes': '1.9', 'Proximal tubular cells': '-0.051', 'Distal tubular cells': '3.1', 'Collecting duct cells': '1.9', 'Mesothelial cells': '0.010', 'Sertoli cells': '-0.532', 'Granulosa cells': '8.1', 'Enteroendocrine cells': '27.6', 'Pancreatic endocrine cells': '40.8', 'Leydig cells': '-0.528', 'Excitatory neurons': '0.7', 'Inhibitory neurons': '0.5', 'Cone photoreceptor cells': '0.0', 'Rod photoreceptor cells': '2.5', 'Bipolar cells': '1.1', 'Horizontal cells': '2.5', 'Astrocytes': '0.0', 'Oligodendrocyte precursor cells': '0.0', 'Oligodendrocytes': '2.4', 'Microglial cells': '0.9', 'Muller glia cells': '0.6', 'Schwann cells': '0.130', 'Spermatogonia': '-0.246', 'Spermatocytes': '0.073', 'Early spermatids': '0.560', 'Late spermatids': '0.787', 'Oocytes': '16.9', 'Cytotrophoblasts': '93.6', 'Syncytiotrophoblasts': '44.7', 'Extravillous trophoblasts': '147.4', 'Endothelial cells': '7.7', 'Lymphatic endothelial cells': '0.5', 'Cardiomyocytes': '0.188', 'Skeletal myocytes': '-0.004', 'Smooth muscle cells': '8.8', 'Adipocytes': '1.3', 'Melanocytes': '0.350', 'Fibroblasts': '16.8', 'Peritubular cells': '-0.378', 'Endometrial stromal cells': '8.2', 'Ovarian stromal cells': '0.9', 'Undifferentiated cells': '185.2', 'T-cells': '15.4', 'B-cells': '16.5', 'Plasma cells': '86.5', 'Nk-cells': '12.6', 'Granulocytes': '6.9', 'Monocytes': '0.7', 'Macrophages': '16.7', 'Hofbauer cells': '92.9', 'Kupffer cells': '24.0', 'Dendritic cells': '2.4', 'Langerhans cells': '0.165', 'Erythroid cells': '0.106', 'Adipocytes (Subcutaneous)': '-0.137', 'Adipocytes (Visceral)': '-0.101', 'Breast glandular cells (progenitors)': '0.239', 'Adipocytes (Breast)': '-0.246', 'Colon enterocytes': '0.351', 'Colon enteroendocrine cells': '-0.085', 'Enteric glia cells': '-0.099', 'Mitotic cells (Colon)': '0.689', 'Mitotic cells (Heart)': '0.667', 'Podocytes': '-0.087', 'Ascending Loop of Henle cells': '0.534', 'Intercalated cells': '0.031', 'Cholangiocyte': '0.052', 'NK-cells (Liver)': '0.067', 'Respiratory ciliated cells': '-0.004', 'Mitotic cells (Lung)': '0.810', 'NK-cells (Lung)': '-0.168', 'B-cells (Lung)': '-0.052', 'Alpha cells': '0.213', 'Beta cells': '0.155', 'Prostate glandular cells': '0.218', 'Prostate basal glandular cells': '0.305', 'Urothelial cells': '0.366', 'Keratinocyte (other)': '0.084', 'Keratinocyte (granular)': '-0.413', 'Hair cortex cells': '0.264', 'Inner root sheath cells': '0.359', 'Outer root sheath cells': '0.486', 'Sebaceous gland cells': '0.247', 'Eccrine sweat gland cells': '0.159', 'Adipocytes (Skin)': '-0.057', 'Mitotic cells (Skin)': '0.695', 'Parietal cells': '0.353', 'Chief cells': '0.369', 'Gastric mucous cells': '0.679', 'Gastric enteroendocrine cells': '0.488', 'Mitotic cells (Stomach)': '0.821', 'Parafollicular cells': '-0.019', 'Thyroid glandular cells': '0.257', 'Mitotic cells (Thyroid)': '0.365', 'Adrenal cortex cells': '0.293', 'Adrenal medulla cells': '0.129', 'Mitotic cells (Adrenal gland)': '0.817', 'Minor salivary glandular cells': '0.102', 'Minor salivary gland ductal cells': '-0.273', 'Minor salivary gland basal cells': '0.666', 'Mitotic cells (Minor salivary gland)': '0.895', 'Adipocytes (Minor salivary gland)': '0.117', 'Somatotropes': '0.082', 'Lactotropes': '0.067', 'Gonadotropes': '-0.052', 'Corticotropes': '0.076', 'Thyrotropes': '0.044', 'Undifferentiated cells (Pituitary gland)': '0.059', 'Mitotic cells (Spleen)': '0.885', 'Platelets': '0.159', 'Erythrocytes': '0.310', 'Hematopoietic stem cells': '0.358', 'B-cells (Spleen)': '-0.092', 'NK-cells (Spleen)': '-0.198', 'Amygdala excitatory': '0.3', 'Cerebellar inhibitory': '0.2', 'Cge interneuron': '0.2', 'Deep-layer corticothalamic and 6b': '0.3', 'Deep-layer intratelencephalic': '0.3', 'Deep-layer near-projecting': '0.8', 'Eccentric medium spiny neuron': '0.4', 'Hippocampal ca1-3': '0.4', 'Hippocampal ca4': '0.9', 'Hippocampal dentate gyrus': '0.2', 'Lamp5-lhx6 and chandelier': '0.1', 'Lower rhombic lip': '0.7', 'Mammillary body': '0.5', 'Medium spiny neuron': '0.3', 'Mge interneuron': '0.2', 'Midbrain-derived inhibitory': '0.3', 'Miscellaneous': '0.3', 'Splatter': '0.4', 'Thalamic excitatory': '0.5', 'Upper rhombic lip': '0.0', 'Upper-layer intratelencephalic': '0.5', 'Astrocyte': '0.5', 'Bergmann glia': '0.2', 'Central nervous system macrophage': '0.4', 'Choroid plexus epithelial cell': '0.2', 'Committed oligodendrocyte precursor': '0.4', 'Ependymal cell': '1.1', 'Oligodendrocyte': '1.6', 'Oligodendrocyte precursor cell': '0.2', 'Endothelial cell': '0.1', 'Pericyte': '0.3', 'Vascular associated smooth muscle cell': '0.0', 'Fibroblast': '0.3', 'Leukocyte': '0.3', 'Basophil': '4.7', 'Eosinophil': '0.9', 'Neutrophil': '13.5', 'Classical monocyte': '0.4', 'Non-classical monocyte': '0.6', 'Intermediate monocyte': '2.5', 'T-reg': '13.2', 'GdT-cell': '1.4', 'MAIT T-cell': '2.3', 'Memory CD4 T-cell': '4.4', 'Naive CD4 T-cell': '0.4', 'Memory CD8 T-cell': '4.2', 'Naive CD8 T-cell': '0.4', 'Memory B-cell': '2.0', 'Naive B-cell': '0.6', 'Plasmacytoid DC': '2.7', 'Myeloid DC': '2.5', 'NK-cell': '0.9', 'Total PBMC': '6.3', 'Vd2 gdTCR': '3.0', 'Memory CD4 T-cell Th1\\/Th17': '0.5', 'Memory CD4 T-cell Th17': '0.5', 'Memory CD4 T-cell Th2': '0.7', 'Non-Vd2 gdTCR': '2.8', 'Memory CD4 T-cell Th1': '0.9', 'Memory CD4 T-cell TFH': '0.6', 'Terminal effector memory CD4 T-cell': '3.0', 'Central memory CD8 T-cell': '6.6', 'Effector memory CD8 T-cell': '16.5', 'Terminal effector memory CD8 T-cell': '2.7', 'Non-switched memory B-cell': '4.3', 'Plasmablast': '58.9', 'Switched memory B-cell': '5.0', 'Exhausted memory B-cell': '11.5', 'Progenitor cell': '11.9', 'Memory T-reg': '1.7', 'Naive CD4 T-cell activated': '0.4', 'Naive CD8 T-cell activated': '0.3', 'Naive T-reg': '0.9'}
4D2G, 6EHT, 6GWS, 6IIW
{'Adipose Tissue': 0.3581098546511628, 'Adrenal Gland': 0.4683213333333333, 'Bladder': 0.5697461904761905, 'Blood': 6.4377733713670615, 'Blood Vessel': 0.2171170262172284, 'Brain': 0.2037596642694928, 'Breast': 0.4111872156862745, 'Cervix Uteri': 0.5264963157894736, 'Colon': 1.10737951732991, 'Esophagus': 1.9398750304498271, 'Fallopian Tube': 0.3396, 'Heart': 0.0971625342624854, 'Kidney': 0.4090478651685393, 'Liver': 0.6143054424778761, 'Lung': 1.2743496678200692, 'Muscle': 0.0406215168119551, 'Nerve': 0.1882828481421647, 'Ovary': 0.2730282777777778, 'Pancreas': 0.3273265548780488, 'Pituitary': 0.4056313780918728, 'Prostate': 0.6551157551020408, 'Salivary Gland': 0.926897098765432, 'Skin': 4.78119631840796, 'Small Intestine': 2.485380481283422, 'Spleen': 2.635192531120332, 'Stomach': 1.3098355710306406, 'Testis': 6.981042659279778, 'Thyroid': 0.8270521898928024, 'Uterus': 0.2222339436619718, 'Vagina': 2.0549375}
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92.13, 89.89, 88.17, 88.01, 90.66, 92.6, 93.67, 93.51, 93.97, 96.03, 96.71, 98.09, 97.71, 97.36, 96.44, 96.73, 97.1, 96.75, 96.36, 94.3, 93.48, 94.33, 93.19, 92.99, 92.74, 96.13, 97.23, 96.82, 97.85, 96.97, 96.86, 94.15, 95.22, 96.16, 97.91, 98.01, 97.38, 97.18, 94.71, 92.18, 91.14, 90.68, 94.56, 95.0, 95.71, 94.73, 94.15, 95.03, 95.77, 97.06, 97.24, 97.75, 97.8, 97.68, 97.86, 97.8, 97.91, 97.13, 95.49, 94.14, 92.26, 92.66, 94.13, 94.02, 95.06, 96.06, 97.14, 97.5, 97.54, 97.81, 97.85, 97.86, 97.69, 97.44, 96.39, 95.35, 94.9, 92.8, 94.05, 93.01, 93.14, 93.03, 95.17, 94.88, 96.04, 90.79, 95.33, 94.45, 96.39, 97.1, 96.17, 95.42, 95.74, 95.36, 94.04, 93.98, 92.12, 91.27, 91.54, 92.4, 93.63, 95.56, 95.55, 95.66, 96.29, 96.6, 96.34, 95.12, 94.22, 94.79, 94.01, 95.01, 93.22, 92.95, 90.69, 93.42, 94.45, 93.34, 94.58, 94.94, 95.63, 95.6, 96.44, 95.63, 96.46, 94.33, 93.1, 91.06, 84.23, 85.58, 92.16, 93.71, 96.59, 95.68, 96.6, 94.91, 95.46, 93.28, 89.69, 88.08, 90.85, 92.55, 95.6, 95.99, 96.55, 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73.27, 70.36, 72.63, 72.69, 68.11, 66.06, 60.67, 52.64, 44.07, 48.46, 43.79, 36.31]
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[78.92, 85.17, 80.85, 81.7, 73.9, 71.45, 66.77, 63.82, 68.62, 62.03, 61.36, 59.61, 61.13, 69.27, 70.48, 71.41, 76.45, 71.5, 71.68, 73.58, 73.4, 76.85, 72.36, 69.06, 63.53, 61.83, 55.92, 54.1, 58.95, 57.94, 56.42, 55.83, 47.69, 52.34, 45.65, 50.07, 48.35, 56.32, 49.16, 56.66, 54.94, 50.28, 57.18, 58.57, 65.2, 68.38, 68.47, 67.48, 74.63, 84.37, 83.64, 82.94, 86.08, 83.99, 89.35, 90.92, 92.71, 90.13, 94.29, 94.69, 95.43, 93.67, 88.49, 89.16, 87.85, 89.0, 83.86, 83.56, 83.56, 78.95, 64.27, 63.02, 62.68, 60.49, 57.87, 56.9, 59.31, 58.29, 65.64, 59.17, 52.53, 57.73, 56.82, 56.87, 50.75, 51.32, 44.28, 47.22, 53.1, 45.75, 50.24, 49.09, 49.56, 44.45, 47.39, 53.11, 51.36, 52.26, 47.61, 58.34, 56.3, 56.09, 61.43, 57.89, 61.14, 58.08, 52.73, 54.96, 59.01, 60.9, 58.14]
[0.96, 0.96, 0.92, 0.94, 0.89, 0.84, 0.89, 0.77, 0.63, 0.9, 0.61, 0.66, 0.83, 0.86, 0.9, 0.83, 0.88, 0.82, 0.86, 0.78, 0.57, 0.95, 0.67, 0.97, 0.56, 0.98, 0.83, 0.65, 0.87, 0.78, 0.84, 0.73, 0.9, 0.84, 0.92, 0.81, 0.92, 0.81, 0.78, 0.83, 0.87, 0.95, 0.7, 0.81, 0.64, 0.82, 0.97, 0.61, 0.88, 0.73, 0.88, 0.86, 0.81, 0.69, 0.84, 0.87, 0.87, 0.78, 0.42, 0.97, 0.83, 0.66, 0.85, 0.58, 0.73, 0.37, 0.5, 0.73, 0.81, 0.69, 0.59, 0.48, 0.82, 0.9, 0.7, 0.77, 0.91, 0.76, 0.95, 0.94, 0.72, 0.88, 0.8, 0.82, 0.89, 0.64, 0.91, 0.92, 0.77, 0.89, 0.89, 0.78, 0.95, 0.74, 0.93, 0.93, 0.88, 0.85, 0.82, 0.86, 0.91, 0.88, 0.89, 0.85, 0.89, 0.88, 0.82, 1.0, 0.93, 1.0, 0.99]
null
Component of an E-cadherin/ catenin adhesion complex composed of at least E-cadherin/CDH1, beta-catenin/CTNNB1 or gamma-catenin/JUP, and potentially alpha-catenin/CTNNA1. Forms a ternary complex composed of ADAM10, CADH1 and EPHA4,
null
null
KLRG1, SPEF1, DLGAP5, AJAP1, RAPGEF2, RAB8B, PIP5K1C, PKP2, TRPV4, CTNNB1, CAV1, DDR1, TBC1D2, CTNNA1, JUP, CTNND1, PSEN1, LIMA1, CDH1, JUP, ADAM10, CADH1 , EPHA4,
null
null
null
null
Homodimer
null
79.91949
0.474025
65.387297
0.814324
2,970
P12830
Q15303
null
degron_data
CDH1
MGPWSRSLSALLLLLQVSSWLCQEPEPCHPGFDAESYTFTVPRRHLERGRVLGRVNFEDCTGRQRTAYFSLDTRFKVGTDGVITVKRPLRFHNPQIHFLVYAWDSTYRKFSTKVTLNTVGHHHRPPPHQASVSGIQAELLTFPNSSPGLRRQKRDWVIPPISCPENEKGPFPKNLVQIKSNKDKEGKVFYSITGQGADTPPVGVFIIERETGWLKVTEPLDRERIATYTLFSHAVSSNGNAVEDPMEILITVTDQNDNKPEFTQEVFKGSVMEGALPGTSVMEVTATDADDDVNTYNAAIAYTILSQDPELPDKNMFTINRNTGVISVVTTGLDRESFPTYTLVVQAADLQGEGLSTTATAVITVTDTNDNPPIFNPTTYKGQVPENEANVVITTLKVTDADAPNTPAWEAVYTILNDDGGQFVVTTNPVNNDGILKTAKGLDFEAKQQYILHVAVTNVVPFEVSLTTSTATVTVDVLDVNEAPIFVPPEKRVEVSEDFGVGQEITSYTAQEPDTFMEQKITYRIWRDTANWLEINPDTGAISTRAELDREDFEHVKNSTYTALIIATDNGSPVATGTGTLLLILSDVNDNAPIPEPRTIFFCERNPKPQVINIIDADLPPNTSPFTAELTHGASANWTIQYNDPTQESIILKPKMALEVGDYKINLKLMDNQNKDQVTTLEVSVCDCEGAAGVCRKAQPVEAGLQIPAILGILGGILALLILILLLLLFLRRRAVVKEPLLPPEDDTRDNVYYYDEEGGGEEDQDFDLSQLHRGLDARPEVTRNDVAPTLMSVPRYLPRPANPDEIGNFIDENLKAADTDPTAPPYDSLLVFDYEGSGSEAASLSSLNSSESDKDQDYDYLNEWGNRFKKLADMYGGGEDD
Homo sapiens
Cell junction, adherens junction, Cell membrane, Endosome, Golgi apparatus, trans-Golgi network, Cytoplasm, Cell junction, desmosome
Tissue enhanced (parathyroid)
{'Ciliated cells': '119.1', 'Basal respiratory cells': '71.1', 'Club cells': '97.3', 'Ionocytes': '81.0', 'Mucus glandular cells': '155.0', 'Serous glandular cells': '67.8', 'Gastric mucus-secreting cells': '133.2', 'Proximal enterocytes': '140.9', 'Paneth cells': '125.1', 'Distal enterocytes': '307.5', 'Intestinal goblet cells': '173.5', 'Exocrine glandular cells': '-0.605', 'Basal prostatic cells': '68.3', 'Prostatic glandular cells': '186.7', 'Breast glandular cells': '0.773', 'Breast myoepithelial cells': '0.700', 'Glandular and luminal cells': '313.0', 'Secretory cells': '82.3', 'Basal keratinocytes': '102.5', 'Suprabasal keratinocytes': '162.6', 'Basal squamous epithelial cells': '51.0', 'Squamous epithelial cells': '106.9', 'Alveolar cells type 1': '0.437', 'Alveolar cells type 2': '0.706', 'Salivary duct cells': '95.9', 'Ductal cells': '0.541', 'Hepatocytes': '0.600', 'Cholangiocytes': '129.7', 'Proximal tubular cells': '0.042', 'Distal tubular cells': '0.0', 'Collecting duct cells': '143.9', 'Mesothelial cells': '0.799', 'Sertoli cells': '0.252', 'Granulosa cells': '12.9', 'Enteroendocrine cells': '92.4', 'Pancreatic endocrine cells': '78.1', 'Leydig cells': '0.264', 'Excitatory neurons': '0.7', 'Inhibitory neurons': '1.3', 'Cone photoreceptor cells': '0.0', 'Rod photoreceptor cells': '0.0', 'Bipolar cells': '0.2', 'Horizontal cells': '0.6', 'Astrocytes': '0.6', 'Oligodendrocyte precursor cells': '0.5', 'Oligodendrocytes': '29.9', 'Microglial cells': '0.9', 'Muller glia cells': '0.1', 'Schwann cells': '0.131', 'Spermatogonia': '0.392', 'Spermatocytes': '0.193', 'Early spermatids': '-0.217', 'Late spermatids': '-0.290', 'Oocytes': '16.9', 'Cytotrophoblasts': '119.2', 'Syncytiotrophoblasts': '45.0', 'Extravillous trophoblasts': '24.9', 'Endothelial cells': '6.1', 'Lymphatic endothelial cells': '0.4', 'Cardiomyocytes': '0.135', 'Skeletal myocytes': '0.107', 'Smooth muscle cells': '5.8', 'Adipocytes': '2.1', 'Melanocytes': '0.335', 'Fibroblasts': '6.5', 'Peritubular cells': '0.210', 'Endometrial stromal cells': '27.7', 'Ovarian stromal cells': '0.7', 'Undifferentiated cells': '101.6', 'T-cells': '2.9', 'B-cells': '4.4', 'Plasma cells': '6.1', 'Nk-cells': '0.0', 'Granulocytes': '8.4', 'Monocytes': '0.0', 'Macrophages': '6.0', 'Hofbauer cells': '4.3', 'Kupffer cells': '1.0', 'Dendritic cells': '5.9', 'Langerhans cells': '0.304', 'Erythroid cells': '0.036', 'Adipocytes (Subcutaneous)': '-0.081', 'Adipocytes (Visceral)': '-0.209', 'Breast glandular cells (progenitors)': '0.538', 'Adipocytes (Breast)': '-0.689', 'Colon enterocytes': '0.790', 'Colon enteroendocrine cells': '0.112', 'Enteric glia cells': '-0.048', 'Mitotic cells (Colon)': '0.299', 'Mitotic cells (Heart)': '0.120', 'Podocytes': '-0.118', 'Ascending Loop of Henle cells': '0.475', 'Intercalated cells': '0.212', 'Cholangiocyte': '0.090', 'NK-cells (Liver)': '-0.005', 'Respiratory ciliated cells': '-0.012', 'Mitotic cells (Lung)': '0.071', 'NK-cells (Lung)': '-0.266', 'B-cells (Lung)': '-0.296', 'Alpha cells': '0.270', 'Beta cells': '0.152', 'Prostate glandular cells': '0.764', 'Prostate basal glandular cells': '0.540', 'Urothelial cells': '0.205', 'Keratinocyte (other)': '0.510', 'Keratinocyte (granular)': '0.055', 'Hair cortex cells': '0.080', 'Inner root sheath cells': '0.131', 'Outer root sheath cells': '0.175', 'Sebaceous gland cells': '0.156', 'Eccrine sweat gland cells': '-0.207', 'Adipocytes (Skin)': '-0.244', 'Mitotic cells (Skin)': '0.442', 'Parietal cells': '0.654', 'Chief cells': '0.649', 'Gastric mucous cells': '0.781', 'Gastric enteroendocrine cells': '0.590', 'Mitotic cells (Stomach)': '0.445', 'Parafollicular cells': '0.173', 'Thyroid glandular cells': '0.865', 'Mitotic cells (Thyroid)': '-0.081', 'Adrenal cortex cells': '0.051', 'Adrenal medulla cells': '0.087', 'Mitotic cells (Adrenal gland)': '0.072', 'Minor salivary glandular cells': '0.371', 'Minor salivary gland ductal cells': '-0.142', 'Minor salivary gland basal cells': '0.582', 'Mitotic cells (Minor salivary gland)': '0.567', 'Adipocytes (Minor salivary gland)': '0.050', 'Somatotropes': '0.121', 'Lactotropes': '0.322', 'Gonadotropes': '0.330', 'Corticotropes': '0.180', 'Thyrotropes': '0.496', 'Undifferentiated cells (Pituitary gland)': '-0.108', 'Mitotic cells (Spleen)': '-0.228', 'Platelets': '-0.050', 'Erythrocytes': '-0.158', 'Hematopoietic stem cells': '-0.211', 'B-cells (Spleen)': '0.266', 'NK-cells (Spleen)': '0.309', 'Amygdala excitatory': '1.0', 'Cerebellar inhibitory': '0.9', 'Cge interneuron': '0.7', 'Deep-layer corticothalamic and 6b': '1.5', 'Deep-layer intratelencephalic': '0.7', 'Deep-layer near-projecting': '0.7', 'Eccentric medium spiny neuron': '0.6', 'Hippocampal ca1-3': '1.9', 'Hippocampal ca4': '1.2', 'Hippocampal dentate gyrus': '1.1', 'Lamp5-lhx6 and chandelier': '0.5', 'Lower rhombic lip': '0.8', 'Mammillary body': '0.6', 'Medium spiny neuron': '0.7', 'Mge interneuron': '1.7', 'Midbrain-derived inhibitory': '0.7', 'Miscellaneous': '0.9', 'Splatter': '3.8', 'Thalamic excitatory': '0.5', 'Upper rhombic lip': '0.8', 'Upper-layer intratelencephalic': '0.6', 'Astrocyte': '4.4', 'Bergmann glia': '0.2', 'Central nervous system macrophage': '0.6', 'Choroid plexus epithelial cell': '52.1', 'Committed oligodendrocyte precursor': '41.5', 'Ependymal cell': '4.8', 'Oligodendrocyte': '53.1', 'Oligodendrocyte precursor cell': '2.4', 'Endothelial cell': '0.7', 'Pericyte': '0.3', 'Vascular associated smooth muscle cell': '0.0', 'Fibroblast': '17.4', 'Leukocyte': '1.1', 'Basophil': '0.0', 'Eosinophil': '0.0', 'Neutrophil': '0.0', 'Classical monocyte': '0.0', 'Non-classical monocyte': '0.0', 'Intermediate monocyte': '0.0', 'T-reg': '2.3', 'GdT-cell': '0.0', 'MAIT T-cell': '0.0', 'Memory CD4 T-cell': '0.0', 'Naive CD4 T-cell': '0.1', 'Memory CD8 T-cell': '0.2', 'Naive CD8 T-cell': '0.3', 'Memory B-cell': '0.0', 'Naive B-cell': '0.1', 'Plasmacytoid DC': '46.6', 'Myeloid DC': '8.5', 'NK-cell': '0.1', 'Total PBMC': '0.7', 'Vd2 gdTCR': '0.0', 'Memory CD4 T-cell Th1\\/Th17': '0.1', 'Memory CD4 T-cell Th17': '0.2', 'Memory CD4 T-cell Th2': '2.9', 'Non-Vd2 gdTCR': '0.1', 'Memory CD4 T-cell Th1': '0.3', 'Memory CD4 T-cell TFH': '0.5', 'Terminal effector memory CD4 T-cell': '0.0', 'Central memory CD8 T-cell': '4.8', 'Effector memory CD8 T-cell': '0.0', 'Terminal effector memory CD8 T-cell': '0.6', 'Non-switched memory B-cell': '0.0', 'Plasmablast': '3.3', 'Switched memory B-cell': '0.0', 'Exhausted memory B-cell': '0.7', 'Progenitor cell': '2.3', 'Memory T-reg': '1.3', 'Naive CD4 T-cell activated': '0.3', 'Naive CD8 T-cell activated': '0.6', 'Naive T-reg': '0.1'}
1O6S, 2O72, 2OMT, 2OMU, 2OMV, 2OMX, 2OMY, 2OMZ, 3FF7, 3FF8, 3L6X, 3L6Y, 4ZT1, 4ZTE, 6CXY, 6OLE, 6OLF, 6OLG, 6VEL, 7STZ, 8H62
{'Adipose Tissue': 1.2125261088039867, 'Adrenal Gland': 0.1914223992248062, 'Bladder': 39.2033519047619, 'Blood': 1.340954264800861, 'Blood Vessel': 0.3121561692883895, 'Brain': 0.8550442199091597, 'Breast': 38.54918344226579, 'Cervix Uteri': 23.539115789473684, 'Colon': 43.41292142490372, 'Esophagus': 53.97513367404844, 'Fallopian Tube': 14.900277777777776, 'Heart': 0.119140469221835, 'Kidney': 25.040449438202245, 'Liver': 26.60802654867257, 'Lung': 35.447986366782004, 'Muscle': 0.1378936151930261, 'Nerve': 17.518468982229404, 'Ovary': 3.6515122222222223, 'Pancreas': 56.89676829268293, 'Pituitary': 24.68741660777385, 'Prostate': 61.279967346938776, 'Salivary Gland': 92.01685185185184, 'Skin': 79.77571720232172, 'Small Intestine': 71.7519320855615, 'Spleen': 10.061029045643156, 'Stomach': 58.07813805013927, 'Testis': 0.8144204986149585, 'Thyroid': 135.176797856049, 'Uterus': 1.442593943661972, 'Vagina': 86.52345512820513}
ERBB4
MKPATGLWVWVSLLVAAGTVQPSDSQSVCAGTENKLSSLSDLEQQYRALRKYYENCEVVMGNLEITSIEHNRDLSFLRSVREVTGYVLVALNQFRYLPLENLRIIRGTKLYEDRYALAIFLNYRKDGNFGLQELGLKNLTEILNGGVYVDQNKFLCYADTIHWQDIVRNPWPSNLTLVSTNGSSGCGRCHKSCTGRCWGPTENHCQTLTRTVCAEQCDGRCYGPYVSDCCHRECAGGCSGPKDTDCFACMNFNDSGACVTQCPQTFVYNPTTFQLEHNFNAKYTYGAFCVKKCPHNFVVDSSSCVRACPSSKMEVEENGIKMCKPCTDICPKACDGIGTGSLMSAQTVDSSNIDKFINCTKINGNLIFLVTGIHGDPYNAIEAIDPEKLNVFRTVREITGFLNIQSWPPNMTDFSVFSNLVTIGGRVLYSGLSLLILKQQGITSLQFQSLKEISAGNIYITDNSNLCYYHTINWTTLFSTINQRIVIRDNRKAENCTAEGMVCNHLCSSDGCWGPGPDQCLSCRRFSRGRICIESCNLYDGEFREFENGSICVECDPQCEKMEDGLLTCHGPGPDNCTKCSHFKDGPNCVEKCPDGLQGANSFIFKYADPDRECHPCHPNCTQGCNGPTSHDCIYYPWTGHSTLPQHARTPLIAAGVIGGLFILVIVGLTFAVYVRRKSIKKKRALRRFLETELVEPLTPSGTAPNQAQLRILKETELKRVKVLGSGAFGTVYKGIWVPEGETVKIPVAIKILNETTGPKANVEFMDEALIMASMDHPHLVRLLGVCLSPTIQLVTQLMPHGCLLEYVHEHKDNIGSQLLLNWCVQIAKGMMYLEERRLVHRDLAARNVLVKSPNHVKITDFGLARLLEGDEKEYNADGGKMPIKWMALECIHYRKFTHQSDVWSYGVTIWELMTFGGKPYDGIPTREIPDLLEKGERLPQPPICTIDVYMVMVKCWMIDADSRPKFKELAAEFSRMARDPQRYLVIQGDDRMKLPSPNDSKFFQNLLDEEDLEDMMDAEEYLVPQAFNIPPPIYTSRARIDSNRSEIGHSPPPAYTPMSGNQFVYRDGGFAAEQGVSVPYRAPTSTIPEAPVAQGATAEIFDDSCCNGTLRKPVAPHVQEDSSTQRYSADPTVFAPERSPRGELDEEGYMTPMRDKPKQEYLNPVEENPFVSRRKNGDLQALDNPEYHNASNGPPKAEDEYVNEPLYLNTFANTLGKAEYLKNNILSMPEKAKKAFDNPDYWNHSLPPRSTLQHPDYLQEYSTKYFYKQNGRIRPIVAENPEYLSEFSLKPGTVLPPPPYRHRNTVV
Homo sapiens
Cell membrane, Nucleus, Mitochondrion
Tissue enhanced (brain, fallopian tube)
{'Ciliated cells': '43.3', 'Basal respiratory cells': '1.0', 'Club cells': '5.5', 'Ionocytes': '2.2', 'Mucus glandular cells': '19.8', 'Serous glandular cells': '18.7', 'Gastric mucus-secreting cells': '0.0', 'Proximal enterocytes': '0.0', 'Paneth cells': '0.0', 'Distal enterocytes': '0.2', 'Intestinal goblet cells': '0.0', 'Exocrine glandular cells': '-0.196', 'Basal prostatic cells': '14.0', 'Prostatic glandular cells': '3.0', 'Breast glandular cells': '0.805', 'Breast myoepithelial cells': '0.591', 'Glandular and luminal cells': '20.8', 'Secretory cells': '35.1', 'Basal keratinocytes': '0.5', 'Suprabasal keratinocytes': '0.5', 'Basal squamous epithelial cells': '0.9', 'Squamous epithelial cells': '0.2', 'Alveolar cells type 1': '0.095', 'Alveolar cells type 2': '0.569', 'Salivary duct cells': '5.7', 'Ductal cells': '0.455', 'Hepatocytes': '0.138', 'Cholangiocytes': '1.9', 'Proximal tubular cells': '0.143', 'Distal tubular cells': '3.1', 'Collecting duct cells': '11.7', 'Mesothelial cells': '0.728', 'Sertoli cells': '0.810', 'Granulosa cells': '2.9', 'Enteroendocrine cells': '0.0', 'Pancreatic endocrine cells': '0.0', 'Leydig cells': '0.501', 'Excitatory neurons': '59.8', 'Inhibitory neurons': '5860.5', 'Cone photoreceptor cells': '0.0', 'Rod photoreceptor cells': '1.5', 'Bipolar cells': '11.3', 'Horizontal cells': '13.2', 'Astrocytes': '1916.0', 'Oligodendrocyte precursor cells': '2222.9', 'Oligodendrocytes': '977.4', 'Microglial cells': '92.1', 'Muller glia cells': '8.6', 'Schwann cells': '0.538', 'Spermatogonia': '0.401', 'Spermatocytes': '0.134', 'Early spermatids': '-0.387', 'Late spermatids': '-0.613', 'Oocytes': '10.3', 'Cytotrophoblasts': '0.1', 'Syncytiotrophoblasts': '0.0', 'Extravillous trophoblasts': '0.2', 'Endothelial cells': '0.8', 'Lymphatic endothelial cells': '0.5', 'Cardiomyocytes': '0.701', 'Skeletal myocytes': '0.401', 'Smooth muscle cells': '4.2', 'Adipocytes': '0.7', 'Melanocytes': '-0.054', 'Fibroblasts': '1.4', 'Peritubular cells': '0.433', 'Endometrial stromal cells': '0.8', 'Ovarian stromal cells': '0.1', 'Undifferentiated cells': '0.1', 'T-cells': '0.3', 'B-cells': '0.1', 'Plasma cells': '0.5', 'Nk-cells': '0.0', 'Granulocytes': '0.4', 'Monocytes': '0.0', 'Macrophages': '0.4', 'Hofbauer cells': '0.1', 'Kupffer cells': '0.0', 'Dendritic cells': '0.0', 'Langerhans cells': '-0.049', 'Erythroid cells': '0.066', 'Adipocytes (Subcutaneous)': '0.043', 'Adipocytes (Visceral)': '-0.064', 'Breast glandular cells (progenitors)': '0.433', 'Adipocytes (Breast)': '-0.572', 'Colon enterocytes': '-0.126', 'Colon enteroendocrine cells': '0.417', 'Enteric glia cells': '0.335', 'Mitotic cells (Colon)': '-0.206', 'Mitotic cells (Heart)': '0.323', 'Podocytes': '0.138', 'Ascending Loop of Henle cells': '0.522', 'Intercalated cells': '0.235', 'Cholangiocyte': '0.258', 'NK-cells (Liver)': '0.137', 'Respiratory ciliated cells': '0.426', 'Mitotic cells (Lung)': '0.031', 'NK-cells (Lung)': '-0.288', 'B-cells (Lung)': '-0.160', 'Alpha cells': '0.211', 'Beta cells': '0.161', 'Prostate glandular cells': '0.210', 'Prostate basal glandular cells': '0.403', 'Urothelial cells': '0.338', 'Keratinocyte (other)': '-0.128', 'Keratinocyte (granular)': '-0.176', 'Hair cortex cells': '0.170', 'Inner root sheath cells': '0.177', 'Outer root sheath cells': '0.254', 'Sebaceous gland cells': '0.064', 'Eccrine sweat gland cells': '0.666', 'Adipocytes (Skin)': '0.238', 'Mitotic cells (Skin)': '0.108', 'Parietal cells': '0.689', 'Chief cells': '0.690', 'Gastric mucous cells': '0.500', 'Gastric enteroendocrine cells': '0.535', 'Mitotic cells (Stomach)': '0.140', 'Parafollicular cells': '0.142', 'Thyroid glandular cells': '0.490', 'Mitotic cells (Thyroid)': '-0.079', 'Adrenal cortex cells': '0.122', 'Adrenal medulla cells': '0.572', 'Mitotic cells (Adrenal gland)': '0.087', 'Minor salivary glandular cells': '0.671', 'Minor salivary gland ductal cells': '0.386', 'Minor salivary gland basal cells': '-0.507', 'Mitotic cells (Minor salivary gland)': '-0.555', 'Adipocytes (Minor salivary gland)': '-0.338', 'Somatotropes': '-0.436', 'Lactotropes': '-0.411', 'Gonadotropes': '-0.077', 'Corticotropes': '0.121', 'Thyrotropes': '0.067', 'Undifferentiated cells (Pituitary gland)': '0.607', 'Mitotic cells (Spleen)': '-0.207', 'Platelets': '-0.165', 'Erythrocytes': '-0.071', 'Hematopoietic stem cells': '-0.203', 'B-cells (Spleen)': '0.117', 'NK-cells (Spleen)': '0.233', 'Amygdala excitatory': '147.9', 'Cerebellar inhibitory': '19.4', 'Cge interneuron': '8806.8', 'Deep-layer corticothalamic and 6b': '161.1', 'Deep-layer intratelencephalic': '44.3', 'Deep-layer near-projecting': '39.7', 'Eccentric medium spiny neuron': '8570.1', 'Hippocampal ca1-3': '32.7', 'Hippocampal ca4': '9.7', 'Hippocampal dentate gyrus': '25.1', 'Lamp5-lhx6 and chandelier': '11575.6', 'Lower rhombic lip': '1192.2', 'Mammillary body': '32.7', 'Medium spiny neuron': '1394.4', 'Mge interneuron': '8483.6', 'Midbrain-derived inhibitory': '120.7', 'Miscellaneous': '330.7', 'Splatter': '2055.3', 'Thalamic excitatory': '115.4', 'Upper rhombic lip': '1183.4', 'Upper-layer intratelencephalic': '37.6', 'Astrocyte': '3770.2', 'Bergmann glia': '1997.7', 'Central nervous system macrophage': '41.4', 'Choroid plexus epithelial cell': '408.5', 'Committed oligodendrocyte precursor': '3149.7', 'Ependymal cell': '2292.5', 'Oligodendrocyte': '1798.7', 'Oligodendrocyte precursor cell': '3808.6', 'Endothelial cell': '46.0', 'Pericyte': '69.0', 'Vascular associated smooth muscle cell': '562.4', 'Fibroblast': '63.5', 'Leukocyte': '46.1', 'Basophil': '0.0', 'Eosinophil': '0.0', 'Neutrophil': '0.0', 'Classical monocyte': '0.0', 'Non-classical monocyte': '0.0', 'Intermediate monocyte': '0.0', 'T-reg': '0.0', 'GdT-cell': '0.0', 'MAIT T-cell': '0.0', 'Memory CD4 T-cell': '0.0', 'Naive CD4 T-cell': '0.0', 'Memory CD8 T-cell': '0.0', 'Naive CD8 T-cell': '0.0', 'Memory B-cell': '0.0', 'Naive B-cell': '0.0', 'Plasmacytoid DC': '0.0', 'Myeloid DC': '0.0', 'NK-cell': '0.0', 'Total PBMC': '0.0', 'Vd2 gdTCR': '0.0', 'Memory CD4 T-cell Th1\\/Th17': '0.0', 'Memory CD4 T-cell Th17': '0.0', 'Memory CD4 T-cell Th2': '0.0', 'Non-Vd2 gdTCR': '0.0', 'Memory CD4 T-cell Th1': '0.0', 'Memory CD4 T-cell TFH': '0.0', 'Terminal effector memory CD4 T-cell': '0.0', 'Central memory CD8 T-cell': '0.0', 'Effector memory CD8 T-cell': '0.0', 'Terminal effector memory CD8 T-cell': '0.0', 'Non-switched memory B-cell': '0.0', 'Plasmablast': '0.0', 'Switched memory B-cell': '0.0', 'Exhausted memory B-cell': '0.0', 'Progenitor cell': '0.0', 'Memory T-reg': '0.0', 'Naive CD4 T-cell activated': '0.0', 'Naive CD8 T-cell activated': '0.0', 'Naive T-reg': '0.0'}
2AHX, 2L2T, 2LCX, 2R4B, 3BBT, 3BBW, 3BCE, 3U2P, 3U7U, 3U9U, 8U4I, 8U4J, 8U4K, 8U4L
{'Adipose Tissue': 0.3812826387043189, 'Adrenal Gland': 0.1074241162790697, 'Bladder': 0.2619505238095238, 'Blood': 0.0089877201291711, 'Blood Vessel': 4.833504868913858, 'Brain': 6.451171196063588, 'Breast': 3.3113276209150326, 'Cervix Uteri': 1.0675215789473682, 'Colon': 0.1006024313222079, 'Esophagus': 0.0905226996539792, 'Fallopian Tube': 11.173333333333334, 'Heart': 1.5844851184668989, 'Kidney': 3.2344685393258428, 'Liver': 0.0179609336283185, 'Lung': 1.3194758650519032, 'Muscle': 0.8907386052303861, 'Nerve': 1.271967689822294, 'Ovary': 0.2119868333333333, 'Pancreas': 0.3690128048780488, 'Pituitary': 5.2564667844522965, 'Prostate': 0.3224207346938775, 'Salivary Gland': 2.7846685185185187, 'Skin': 0.3008394632393587, 'Small Intestine': 0.0590433636363636, 'Spleen': 0.0745424107883817, 'Stomach': 0.4317559721448468, 'Testis': 5.409421052631579, 'Thyroid': 2.26434134762634, 'Uterus': 0.1600107746478873, 'Vagina': 0.1911400769230769}
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null
Component of an E-cadherin/ catenin adhesion complex composed of at least E-cadherin/CDH1, beta-catenin/CTNNB1 or gamma-catenin/JUP, and potentially alpha-catenin/CTNNA1. Forms a ternary complex composed of ADAM10, CADH1 and EPHA4,
null
null
KLRG1, SPEF1, DLGAP5, AJAP1, RAPGEF2, RAB8B, PIP5K1C, PKP2, TRPV4, CTNNB1, CAV1, DDR1, TBC1D2, CTNNA1, JUP, CTNND1, PSEN1, LIMA1, CDH1, JUP, ADAM10, CADH1 , EPHA4,
null
null
null
null
Homodimer
null
79.91949
0.474025
73.038341
0.465153
258
P12830
Q15398
null
degron_data
CDH1
MGPWSRSLSALLLLLQVSSWLCQEPEPCHPGFDAESYTFTVPRRHLERGRVLGRVNFEDCTGRQRTAYFSLDTRFKVGTDGVITVKRPLRFHNPQIHFLVYAWDSTYRKFSTKVTLNTVGHHHRPPPHQASVSGIQAELLTFPNSSPGLRRQKRDWVIPPISCPENEKGPFPKNLVQIKSNKDKEGKVFYSITGQGADTPPVGVFIIERETGWLKVTEPLDRERIATYTLFSHAVSSNGNAVEDPMEILITVTDQNDNKPEFTQEVFKGSVMEGALPGTSVMEVTATDADDDVNTYNAAIAYTILSQDPELPDKNMFTINRNTGVISVVTTGLDRESFPTYTLVVQAADLQGEGLSTTATAVITVTDTNDNPPIFNPTTYKGQVPENEANVVITTLKVTDADAPNTPAWEAVYTILNDDGGQFVVTTNPVNNDGILKTAKGLDFEAKQQYILHVAVTNVVPFEVSLTTSTATVTVDVLDVNEAPIFVPPEKRVEVSEDFGVGQEITSYTAQEPDTFMEQKITYRIWRDTANWLEINPDTGAISTRAELDREDFEHVKNSTYTALIIATDNGSPVATGTGTLLLILSDVNDNAPIPEPRTIFFCERNPKPQVINIIDADLPPNTSPFTAELTHGASANWTIQYNDPTQESIILKPKMALEVGDYKINLKLMDNQNKDQVTTLEVSVCDCEGAAGVCRKAQPVEAGLQIPAILGILGGILALLILILLLLLFLRRRAVVKEPLLPPEDDTRDNVYYYDEEGGGEEDQDFDLSQLHRGLDARPEVTRNDVAPTLMSVPRYLPRPANPDEIGNFIDENLKAADTDPTAPPYDSLLVFDYEGSGSEAASLSSLNSSESDKDQDYDYLNEWGNRFKKLADMYGGGEDD
Homo sapiens
Cell junction, adherens junction, Cell membrane, Endosome, Golgi apparatus, trans-Golgi network, Cytoplasm, Cell junction, desmosome
Tissue enhanced (parathyroid)
{'Ciliated cells': '119.1', 'Basal respiratory cells': '71.1', 'Club cells': '97.3', 'Ionocytes': '81.0', 'Mucus glandular cells': '155.0', 'Serous glandular cells': '67.8', 'Gastric mucus-secreting cells': '133.2', 'Proximal enterocytes': '140.9', 'Paneth cells': '125.1', 'Distal enterocytes': '307.5', 'Intestinal goblet cells': '173.5', 'Exocrine glandular cells': '-0.605', 'Basal prostatic cells': '68.3', 'Prostatic glandular cells': '186.7', 'Breast glandular cells': '0.773', 'Breast myoepithelial cells': '0.700', 'Glandular and luminal cells': '313.0', 'Secretory cells': '82.3', 'Basal keratinocytes': '102.5', 'Suprabasal keratinocytes': '162.6', 'Basal squamous epithelial cells': '51.0', 'Squamous epithelial cells': '106.9', 'Alveolar cells type 1': '0.437', 'Alveolar cells type 2': '0.706', 'Salivary duct cells': '95.9', 'Ductal cells': '0.541', 'Hepatocytes': '0.600', 'Cholangiocytes': '129.7', 'Proximal tubular cells': '0.042', 'Distal tubular cells': '0.0', 'Collecting duct cells': '143.9', 'Mesothelial cells': '0.799', 'Sertoli cells': '0.252', 'Granulosa cells': '12.9', 'Enteroendocrine cells': '92.4', 'Pancreatic endocrine cells': '78.1', 'Leydig cells': '0.264', 'Excitatory neurons': '0.7', 'Inhibitory neurons': '1.3', 'Cone photoreceptor cells': '0.0', 'Rod photoreceptor cells': '0.0', 'Bipolar cells': '0.2', 'Horizontal cells': '0.6', 'Astrocytes': '0.6', 'Oligodendrocyte precursor cells': '0.5', 'Oligodendrocytes': '29.9', 'Microglial cells': '0.9', 'Muller glia cells': '0.1', 'Schwann cells': '0.131', 'Spermatogonia': '0.392', 'Spermatocytes': '0.193', 'Early spermatids': '-0.217', 'Late spermatids': '-0.290', 'Oocytes': '16.9', 'Cytotrophoblasts': '119.2', 'Syncytiotrophoblasts': '45.0', 'Extravillous trophoblasts': '24.9', 'Endothelial cells': '6.1', 'Lymphatic endothelial cells': '0.4', 'Cardiomyocytes': '0.135', 'Skeletal myocytes': '0.107', 'Smooth muscle cells': '5.8', 'Adipocytes': '2.1', 'Melanocytes': '0.335', 'Fibroblasts': '6.5', 'Peritubular cells': '0.210', 'Endometrial stromal cells': '27.7', 'Ovarian stromal cells': '0.7', 'Undifferentiated cells': '101.6', 'T-cells': '2.9', 'B-cells': '4.4', 'Plasma cells': '6.1', 'Nk-cells': '0.0', 'Granulocytes': '8.4', 'Monocytes': '0.0', 'Macrophages': '6.0', 'Hofbauer cells': '4.3', 'Kupffer cells': '1.0', 'Dendritic cells': '5.9', 'Langerhans cells': '0.304', 'Erythroid cells': '0.036', 'Adipocytes (Subcutaneous)': '-0.081', 'Adipocytes (Visceral)': '-0.209', 'Breast glandular cells (progenitors)': '0.538', 'Adipocytes (Breast)': '-0.689', 'Colon enterocytes': '0.790', 'Colon enteroendocrine cells': '0.112', 'Enteric glia cells': '-0.048', 'Mitotic cells (Colon)': '0.299', 'Mitotic cells (Heart)': '0.120', 'Podocytes': '-0.118', 'Ascending Loop of Henle cells': '0.475', 'Intercalated cells': '0.212', 'Cholangiocyte': '0.090', 'NK-cells (Liver)': '-0.005', 'Respiratory ciliated cells': '-0.012', 'Mitotic cells (Lung)': '0.071', 'NK-cells (Lung)': '-0.266', 'B-cells (Lung)': '-0.296', 'Alpha cells': '0.270', 'Beta cells': '0.152', 'Prostate glandular cells': '0.764', 'Prostate basal glandular cells': '0.540', 'Urothelial cells': '0.205', 'Keratinocyte (other)': '0.510', 'Keratinocyte (granular)': '0.055', 'Hair cortex cells': '0.080', 'Inner root sheath cells': '0.131', 'Outer root sheath cells': '0.175', 'Sebaceous gland cells': '0.156', 'Eccrine sweat gland cells': '-0.207', 'Adipocytes (Skin)': '-0.244', 'Mitotic cells (Skin)': '0.442', 'Parietal cells': '0.654', 'Chief cells': '0.649', 'Gastric mucous cells': '0.781', 'Gastric enteroendocrine cells': '0.590', 'Mitotic cells (Stomach)': '0.445', 'Parafollicular cells': '0.173', 'Thyroid glandular cells': '0.865', 'Mitotic cells (Thyroid)': '-0.081', 'Adrenal cortex cells': '0.051', 'Adrenal medulla cells': '0.087', 'Mitotic cells (Adrenal gland)': '0.072', 'Minor salivary glandular cells': '0.371', 'Minor salivary gland ductal cells': '-0.142', 'Minor salivary gland basal cells': '0.582', 'Mitotic cells (Minor salivary gland)': '0.567', 'Adipocytes (Minor salivary gland)': '0.050', 'Somatotropes': '0.121', 'Lactotropes': '0.322', 'Gonadotropes': '0.330', 'Corticotropes': '0.180', 'Thyrotropes': '0.496', 'Undifferentiated cells (Pituitary gland)': '-0.108', 'Mitotic cells (Spleen)': '-0.228', 'Platelets': '-0.050', 'Erythrocytes': '-0.158', 'Hematopoietic stem cells': '-0.211', 'B-cells (Spleen)': '0.266', 'NK-cells (Spleen)': '0.309', 'Amygdala excitatory': '1.0', 'Cerebellar inhibitory': '0.9', 'Cge interneuron': '0.7', 'Deep-layer corticothalamic and 6b': '1.5', 'Deep-layer intratelencephalic': '0.7', 'Deep-layer near-projecting': '0.7', 'Eccentric medium spiny neuron': '0.6', 'Hippocampal ca1-3': '1.9', 'Hippocampal ca4': '1.2', 'Hippocampal dentate gyrus': '1.1', 'Lamp5-lhx6 and chandelier': '0.5', 'Lower rhombic lip': '0.8', 'Mammillary body': '0.6', 'Medium spiny neuron': '0.7', 'Mge interneuron': '1.7', 'Midbrain-derived inhibitory': '0.7', 'Miscellaneous': '0.9', 'Splatter': '3.8', 'Thalamic excitatory': '0.5', 'Upper rhombic lip': '0.8', 'Upper-layer intratelencephalic': '0.6', 'Astrocyte': '4.4', 'Bergmann glia': '0.2', 'Central nervous system macrophage': '0.6', 'Choroid plexus epithelial cell': '52.1', 'Committed oligodendrocyte precursor': '41.5', 'Ependymal cell': '4.8', 'Oligodendrocyte': '53.1', 'Oligodendrocyte precursor cell': '2.4', 'Endothelial cell': '0.7', 'Pericyte': '0.3', 'Vascular associated smooth muscle cell': '0.0', 'Fibroblast': '17.4', 'Leukocyte': '1.1', 'Basophil': '0.0', 'Eosinophil': '0.0', 'Neutrophil': '0.0', 'Classical monocyte': '0.0', 'Non-classical monocyte': '0.0', 'Intermediate monocyte': '0.0', 'T-reg': '2.3', 'GdT-cell': '0.0', 'MAIT T-cell': '0.0', 'Memory CD4 T-cell': '0.0', 'Naive CD4 T-cell': '0.1', 'Memory CD8 T-cell': '0.2', 'Naive CD8 T-cell': '0.3', 'Memory B-cell': '0.0', 'Naive B-cell': '0.1', 'Plasmacytoid DC': '46.6', 'Myeloid DC': '8.5', 'NK-cell': '0.1', 'Total PBMC': '0.7', 'Vd2 gdTCR': '0.0', 'Memory CD4 T-cell Th1\\/Th17': '0.1', 'Memory CD4 T-cell Th17': '0.2', 'Memory CD4 T-cell Th2': '2.9', 'Non-Vd2 gdTCR': '0.1', 'Memory CD4 T-cell Th1': '0.3', 'Memory CD4 T-cell TFH': '0.5', 'Terminal effector memory CD4 T-cell': '0.0', 'Central memory CD8 T-cell': '4.8', 'Effector memory CD8 T-cell': '0.0', 'Terminal effector memory CD8 T-cell': '0.6', 'Non-switched memory B-cell': '0.0', 'Plasmablast': '3.3', 'Switched memory B-cell': '0.0', 'Exhausted memory B-cell': '0.7', 'Progenitor cell': '2.3', 'Memory T-reg': '1.3', 'Naive CD4 T-cell activated': '0.3', 'Naive CD8 T-cell activated': '0.6', 'Naive T-reg': '0.1'}
1O6S, 2O72, 2OMT, 2OMU, 2OMV, 2OMX, 2OMY, 2OMZ, 3FF7, 3FF8, 3L6X, 3L6Y, 4ZT1, 4ZTE, 6CXY, 6OLE, 6OLF, 6OLG, 6VEL, 7STZ, 8H62
{'Adipose Tissue': 1.2125261088039867, 'Adrenal Gland': 0.1914223992248062, 'Bladder': 39.2033519047619, 'Blood': 1.340954264800861, 'Blood Vessel': 0.3121561692883895, 'Brain': 0.8550442199091597, 'Breast': 38.54918344226579, 'Cervix Uteri': 23.539115789473684, 'Colon': 43.41292142490372, 'Esophagus': 53.97513367404844, 'Fallopian Tube': 14.900277777777776, 'Heart': 0.119140469221835, 'Kidney': 25.040449438202245, 'Liver': 26.60802654867257, 'Lung': 35.447986366782004, 'Muscle': 0.1378936151930261, 'Nerve': 17.518468982229404, 'Ovary': 3.6515122222222223, 'Pancreas': 56.89676829268293, 'Pituitary': 24.68741660777385, 'Prostate': 61.279967346938776, 'Salivary Gland': 92.01685185185184, 'Skin': 79.77571720232172, 'Small Intestine': 71.7519320855615, 'Spleen': 10.061029045643156, 'Stomach': 58.07813805013927, 'Testis': 0.8144204986149585, 'Thyroid': 135.176797856049, 'Uterus': 1.442593943661972, 'Vagina': 86.52345512820513}
DLGAP5
MSSSHFASRHRKDISTEMIRTKIAHRKSLSQKENRHKEYERNRHFGLKDVNIPTLEGRILVELDETSQGLVPEKTNVKPRAMKTILGDQRKQMLQKYKEEKQLQKLKEQREKAKRGIFKVGRYRPDMPCFLLSNQNAVKAEPKKAIPSSVRITRSKAKDQMEQTKIDNESDVRAIRPGPRQTSEKKVSDKEKKVVQPVMPTSLRMTRSATQAAKQVPRTVSSTTARKPVTRAANENEPEGKVPSKGRPAKNVETKPDKGISCKVDSEENTLNSQTNATSGMNPDGVLSKMENLPEINTAKIKGKNSFAPKDFMFQPLDGLKTYQVTPMTPRSANAFLTPSYTWTPLKTEVDESQATKEILAQKCKTYSTKTIQQDSNKLPCPLGPLTVWHEEHVLNKNEATTKNLNGLPIKEVPSLERNEGRIAQPHHGVPYFRNILQSETEKLTSHCFEWDRKLELDIPDDAKDLIRTAVGQTRLLMKERFKQFEGLVDDCEYKRGIKETTCTDLDGFWDMVSFQIEDVIHKFNNLIKLEESGWQVNNNMNHNMNKNVFRKKVVSGIASKPKQDDAGRIAARNRLAAIKNAMRERIRQEECAETAVSVIPKEVDKIVFDAGFFRVESPVKLFSGLSVSSEGPSQRLGTPKSVNKAVSQSRNEMGIPQQTTSPENAGPQNTKSEHVKKTLFLSIPESRSSIEDAQCPGLPDLIEENHVVNKTDLKVDCLSSERMSLPLLAGGVADDINTNKKEGISDVVEGMELNSSITSQDVLMSSPEKNTASQNSILEEGETKISQSELFDNKSLTTECHLLDSPGLNCSNPFTQLERRHQEHARHISFGGNLITFSPLQPGEF
Homo sapiens
Nucleus, Cytoplasm, Cytoplasm, cytoskeleton, spindle
Group enriched (bone marrow, lymphoid tissue, testis)
{'Ciliated cells': '4.1', 'Basal respiratory cells': '3.3', 'Club cells': '1.6', 'Ionocytes': '0.7', 'Mucus glandular cells': '1.3', 'Serous glandular cells': '2.4', 'Gastric mucus-secreting cells': '8.8', 'Proximal enterocytes': '0.2', 'Paneth cells': '0.2', 'Distal enterocytes': '0.1', 'Intestinal goblet cells': '4.4', 'Exocrine glandular cells': '-0.249', 'Basal prostatic cells': '0.0', 'Prostatic glandular cells': '0.1', 'Breast glandular cells': '0.118', 'Breast myoepithelial cells': '0.219', 'Glandular and luminal cells': '4.7', 'Secretory cells': '0.5', 'Basal keratinocytes': '8.5', 'Suprabasal keratinocytes': '2.2', 'Basal squamous epithelial cells': '1.3', 'Squamous epithelial cells': '11.7', 'Alveolar cells type 1': '-0.264', 'Alveolar cells type 2': '0.095', 'Salivary duct cells': '1.3', 'Ductal cells': '0.447', 'Hepatocytes': '0.286', 'Cholangiocytes': '0.0', 'Proximal tubular cells': '0.295', 'Distal tubular cells': '0.0', 'Collecting duct cells': '0.0', 'Mesothelial cells': '0.010', 'Sertoli cells': '-0.239', 'Granulosa cells': '11.8', 'Enteroendocrine cells': '0.8', 'Pancreatic endocrine cells': '6.8', 'Leydig cells': '-0.201', 'Excitatory neurons': '0.3', 'Inhibitory neurons': '0.3', 'Cone photoreceptor cells': '0.0', 'Rod photoreceptor cells': '0.0', 'Bipolar cells': '0.0', 'Horizontal cells': '0.0', 'Astrocytes': '0.0', 'Oligodendrocyte precursor cells': '0.0', 'Oligodendrocytes': '0.3', 'Microglial cells': '0.0', 'Muller glia cells': '0.0', 'Schwann cells': '0.125', 'Spermatogonia': '0.213', 'Spermatocytes': '0.688', 'Early spermatids': '0.692', 'Late spermatids': '0.222', 'Oocytes': '355.1', 'Cytotrophoblasts': '12.0', 'Syncytiotrophoblasts': '1.5', 'Extravillous trophoblasts': '23.4', 'Endothelial cells': '1.2', 'Lymphatic endothelial cells': '0.1', 'Cardiomyocytes': '0.241', 'Skeletal myocytes': '0.031', 'Smooth muscle cells': '1.6', 'Adipocytes': '0.1', 'Melanocytes': '0.482', 'Fibroblasts': '2.7', 'Peritubular cells': '-0.201', 'Endometrial stromal cells': '1.8', 'Ovarian stromal cells': '1.1', 'Undifferentiated cells': '15.5', 'T-cells': '3.3', 'B-cells': '1.0', 'Plasma cells': '26.4', 'Nk-cells': '1.3', 'Granulocytes': '0.0', 'Monocytes': '0.0', 'Macrophages': '3.6', 'Hofbauer cells': '8.1', 'Kupffer cells': '2.9', 'Dendritic cells': '0.0', 'Langerhans cells': '0.148', 'Erythroid cells': '0.229', 'Adipocytes (Subcutaneous)': '-0.092', 'Adipocytes (Visceral)': '-0.119', 'Breast glandular cells (progenitors)': '0.193', 'Adipocytes (Breast)': '-0.080', 'Colon enterocytes': '0.318', 'Colon enteroendocrine cells': '-0.132', 'Enteric glia cells': '-0.212', 'Mitotic cells (Colon)': '0.747', 'Mitotic cells (Heart)': '0.758', 'Podocytes': '-0.091', 'Ascending Loop of Henle cells': '0.129', 'Intercalated cells': '-0.141', 'Cholangiocyte': '0.280', 'NK-cells (Liver)': '-0.073', 'Respiratory ciliated cells': '0.011', 'Mitotic cells (Lung)': '0.883', 'NK-cells (Lung)': '-0.078', 'B-cells (Lung)': '0.062', 'Alpha cells': '0.116', 'Beta cells': '0.006', 'Prostate glandular cells': '-0.109', 'Prostate basal glandular cells': '0.127', 'Urothelial cells': '0.168', 'Keratinocyte (other)': '0.209', 'Keratinocyte (granular)': '-0.238', 'Hair cortex cells': '0.180', 'Inner root sheath cells': '0.346', 'Outer root sheath cells': '0.346', 'Sebaceous gland cells': '0.098', 'Eccrine sweat gland cells': '0.037', 'Adipocytes (Skin)': '-0.094', 'Mitotic cells (Skin)': '0.909', 'Parietal cells': '0.212', 'Chief cells': '0.172', 'Gastric mucous cells': '0.606', 'Gastric enteroendocrine cells': '0.266', 'Mitotic cells (Stomach)': '0.916', 'Parafollicular cells': '-0.062', 'Thyroid glandular cells': '-0.119', 'Mitotic cells (Thyroid)': '0.783', 'Adrenal cortex cells': '0.459', 'Adrenal medulla cells': '0.140', 'Mitotic cells (Adrenal gland)': '0.940', 'Minor salivary glandular cells': '0.113', 'Minor salivary gland ductal cells': '-0.327', 'Minor salivary gland basal cells': '0.651', 'Mitotic cells (Minor salivary gland)': '0.956', 'Adipocytes (Minor salivary gland)': '0.133', 'Somatotropes': '-0.175', 'Lactotropes': '-0.168', 'Gonadotropes': '-0.137', 'Corticotropes': '-0.197', 'Thyrotropes': '-0.127', 'Undifferentiated cells (Pituitary gland)': '0.282', 'Mitotic cells (Spleen)': '0.948', 'Platelets': '0.193', 'Erythrocytes': '0.329', 'Hematopoietic stem cells': '0.399', 'B-cells (Spleen)': '-0.134', 'NK-cells (Spleen)': '-0.237', 'Amygdala excitatory': '0.2', 'Cerebellar inhibitory': '0.2', 'Cge interneuron': '0.2', 'Deep-layer corticothalamic and 6b': '0.2', 'Deep-layer intratelencephalic': '0.3', 'Deep-layer near-projecting': '0.3', 'Eccentric medium spiny neuron': '0.3', 'Hippocampal ca1-3': '0.1', 'Hippocampal ca4': '0.4', 'Hippocampal dentate gyrus': '0.3', 'Lamp5-lhx6 and chandelier': '0.2', 'Lower rhombic lip': '0.2', 'Mammillary body': '0.2', 'Medium spiny neuron': '0.3', 'Mge interneuron': '0.3', 'Midbrain-derived inhibitory': '0.2', 'Miscellaneous': '0.2', 'Splatter': '0.2', 'Thalamic excitatory': '0.4', 'Upper rhombic lip': '0.2', 'Upper-layer intratelencephalic': '0.2', 'Astrocyte': '0.2', 'Bergmann glia': '0.6', 'Central nervous system macrophage': '0.3', 'Choroid plexus epithelial cell': '0.1', 'Committed oligodendrocyte precursor': '0.5', 'Ependymal cell': '0.3', 'Oligodendrocyte': '0.3', 'Oligodendrocyte precursor cell': '0.3', 'Endothelial cell': '0.3', 'Pericyte': '0.4', 'Vascular associated smooth muscle cell': '0.0', 'Fibroblast': '0.3', 'Leukocyte': '0.5', 'Basophil': '0.0', 'Eosinophil': '0.0', 'Neutrophil': '0.5', 'Classical monocyte': '0.0', 'Non-classical monocyte': '0.1', 'Intermediate monocyte': '0.0', 'T-reg': '3.7', 'GdT-cell': '0.0', 'MAIT T-cell': '0.1', 'Memory CD4 T-cell': '1.9', 'Naive CD4 T-cell': '0.0', 'Memory CD8 T-cell': '1.4', 'Naive CD8 T-cell': '0.0', 'Memory B-cell': '0.6', 'Naive B-cell': '0.0', 'Plasmacytoid DC': '0.0', 'Myeloid DC': '0.6', 'NK-cell': '0.4', 'Total PBMC': '2.0', 'Vd2 gdTCR': '0.4', 'Memory CD4 T-cell Th1\\/Th17': '0.0', 'Memory CD4 T-cell Th17': '0.2', 'Memory CD4 T-cell Th2': '0.2', 'Non-Vd2 gdTCR': '0.1', 'Memory CD4 T-cell Th1': '0.6', 'Memory CD4 T-cell TFH': '0.0', 'Terminal effector memory CD4 T-cell': '0.0', 'Central memory CD8 T-cell': '1.5', 'Effector memory CD8 T-cell': '9.2', 'Terminal effector memory CD8 T-cell': '0.4', 'Non-switched memory B-cell': '0.8', 'Plasmablast': '35.1', 'Switched memory B-cell': '1.4', 'Exhausted memory B-cell': '2.7', 'Progenitor cell': '0.9', 'Memory T-reg': '2.1', 'Naive CD4 T-cell activated': '0.0', 'Naive CD8 T-cell activated': '0.0', 'Naive T-reg': '0.2'}
7ZX4
{'Adipose Tissue': 0.4733697259136212, 'Adrenal Gland': 0.556333523255814, 'Bladder': 0.4962204761904761, 'Blood': 14.210095091496234, 'Blood Vessel': 0.2836036479400748, 'Brain': 0.0341074837244511, 'Breast': 0.4279732897603486, 'Cervix Uteri': 0.8072463157894737, 'Colon': 1.567956611039795, 'Esophagus': 3.162706170934256, 'Fallopian Tube': 0.1973311111111111, 'Heart': 0.1468218443670151, 'Kidney': 0.3380416179775281, 'Liver': 0.3461185752212389, 'Lung': 1.4922000000000002, 'Muscle': 0.0454074906600249, 'Nerve': 0.2317578093699515, 'Ovary': 0.5267686666666667, 'Pancreas': 0.0993034603658536, 'Pituitary': 0.1051416254416961, 'Prostate': 0.3436373591836735, 'Salivary Gland': 1.313061728395062, 'Skin': 13.55756097291321, 'Small Intestine': 3.405900855614973, 'Spleen': 4.446368049792531, 'Stomach': 1.7007704986072425, 'Testis': 21.506673130193903, 'Thyroid': 0.3346837212863706, 'Uterus': 0.2004799295774648, 'Vagina': 2.8676192307692308}
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[1.0, 0.99, 0.98, 0.78, 0.74, 0.73, 0.64, 0.53, 0.74, 0.81, 0.8, 0.84, 0.53, 0.8, 0.55, 0.6, 0.52, 0.34, 0.44, 0.55, 0.53, 0.47, 0.5, 0.5, 0.59, 0.75, 0.66, 0.52, 0.52, 0.38, 0.55, 0.67, 0.51, 0.54, 0.57, 0.55, 0.54, 0.43, 0.6, 0.45, 0.69, 0.77, 0.65, 0.72, 0.88, 0.76, 0.86, 0.85, 0.56, 0.91, 0.88, 0.66, 0.85, 0.76, 0.76, 0.86, 0.73, 0.89, 0.8, 0.94, 0.82, 0.92, 0.97, 0.98, 1.0, 0.97, 1.0, 1.0, 1.0, 0.99, 0.96, 0.94, 0.86, 0.97, 0.77, 0.97, 0.87, 0.92, 0.93, 0.69, 0.57, 0.79, 0.86, 0.4, 0.61, 0.68, 0.33, 0.28, 0.61, 0.69, 0.63, 0.65, 0.67, 0.51, 0.51, 0.65, 0.56, 0.61, 0.45, 0.64, 0.4, 0.64, 0.62, 0.52, 0.67, 0.52, 0.72, 0.47, 0.68, 0.68, 0.47, 0.6, 0.74, 0.84, 0.67, 0.52, 0.84, 0.83, 0.88, 0.8, 0.75, 0.93, 0.82, 0.91, 0.71, 0.87, 0.86, 0.45, 0.72, 0.87, 0.84, 0.71, 0.92, 0.78, 0.96, 0.98, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 0.92, 0.98, 0.88, 0.83, 0.85, 0.76, 0.92, 0.62, 0.61, 0.93, 0.78, 0.56, 0.59, 0.81, 0.52, 0.7, 0.86, 0.92, 0.88, 0.86, 0.9, 0.93, 0.86, 0.92, 0.97, 0.97, 1.0, 1.0, 1.0, 1.0, 1.0, 0.98, 1.0, 0.98, 0.97, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 0.99, 1.0, 0.99, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 0.98, 1.0, 0.93, 1.0, 0.81, 1.0, 0.94, 1.0, 0.98, 0.99, 0.99, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 0.97, 0.99, 0.97, 0.98, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 0.99, 1.0, 0.97, 1.0, 0.96, 1.0, 0.94, 1.0, 0.95, 1.0, 1.0, 0.81, 0.98, 0.78, 0.91, 0.95, 0.89, 0.99, 0.98, 1.0, 1.0, 1.0, 0.95, 1.0, 0.92, 1.0, 0.96, 0.9, 0.96, 0.85, 0.93, 0.97, 0.85, 0.89, 0.91, 0.76, 0.99, 0.73, 1.0, 0.98, 1.0, 1.0, 0.91, 1.0, 0.91, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 0.98, 1.0, 0.99, 1.0, 1.0, 1.0, 1.0, 0.99, 0.94, 0.99, 0.95, 1.0, 1.0, 0.99, 1.0, 0.98, 0.96, 0.99, 0.92, 0.95, 0.81, 0.95, 0.89, 0.94, 0.85, 0.91, 0.97, 0.75, 0.98, 0.4, 0.68, 0.99, 0.96, 0.61, 0.86, 0.8, 0.81, 0.81, 0.74, 0.9, 0.89, 0.71, 0.8, 0.82, 0.84, 0.84, 0.71, 0.76, 0.76, 0.82, 0.79, 0.39, 0.97, 0.53, 0.65, 0.71, 0.47, 0.68, 0.82, 0.75, 0.69, 0.75, 0.88, 0.82, 0.82, 0.9, 0.74, 0.88, 0.81, 0.7, 0.8, 0.92, 1.0, 0.95, 0.99, 1.0, 0.99, 1.0, 0.99, 0.98, 1.0, 0.98, 0.94, 0.92, 0.94, 0.84, 0.86, 0.87, 0.94, 0.86, 0.95, 0.94, 0.94, 0.93, 0.97, 1.0, 0.99, 0.99, 0.99, 1.0, 1.0, 1.0, 1.0, 1.0, 0.99, 0.96, 0.92, 0.95, 0.83, 0.88, 0.91, 0.84, 0.76, 0.89, 0.78, 0.94, 0.93, 0.98, 0.93, 0.99, 1.0, 1.0, 1.0, 1.0, 1.0, 0.8, 1.0, 0.87, 0.99, 0.88, 1.0, 0.83, 0.97, 0.91, 0.92, 0.93, 0.86, 0.94, 0.83, 0.89, 0.75, 0.87, 0.82, 0.97, 0.89, 0.84, 0.71, 0.62, 0.77, 0.25, 0.43, 0.16, 0.66, 0.45, 0.01, 0.34, 0.63, 0.23, 0.14, 0.57, 0.44, 0.14, 0.33, 0.53, 0.4, 0.0, 0.3, 0.5, 0.3, 0.02, 0.61, 0.53, 0.03, 0.28, 0.73, 0.26, 0.24, 0.82, 0.58, 0.93, 0.07, 0.52, 0.64, 0.71, 0.05, 0.13, 0.5, 0.44, 0.0, 0.51, 0.5, 0.04, 0.03, 0.45, 0.41, 0.0, 0.38, 0.59, 0.06, 0.17, 0.79, 0.54, 0.3, 0.04, 0.68, 0.38, 0.0, 0.47, 0.36, 0.24, 0.02, 0.33, 0.28, 0.13, 0.53, 0.66, 0.74, 0.8, 0.29, 0.99, 0.86, 0.83, 0.17, 0.54, 0.3, 0.53, 0.48, 0.0, 0.18, 0.51, 0.19, 0.12, 0.62, 0.41, 0.0, 0.24, 0.7, 0.29, 0.05, 0.6, 0.49, 0.06, 0.23, 0.42, 0.26, 0.02, 0.41, 0.34, 0.05, 0.4, 0.58, 0.11, 0.35, 0.71, 0.31, 0.58, 0.19, 0.65, 0.43, 0.61, 0.75, 0.88, 0.75, 0.63, 0.74, 0.63, 0.75, 0.73, 0.6, 0.93, 0.75, 0.94, 0.6, 0.96, 0.92, 0.98, 0.93, 0.98, 0.87, 0.99, 1.0, 0.99, 0.98, 1.0, 0.86, 0.93, 0.51, 0.5, 0.63, 0.54, 0.48, 0.54, 0.41, 0.52, 0.55, 0.66, 0.72, 0.55, 0.42, 0.53, 0.62, 0.59, 0.57, 0.49, 0.64, 0.63, 0.5, 0.75, 0.47, 0.61, 0.6, 0.66, 0.71, 0.72, 0.54, 0.88, 0.85, 0.79, 0.99, 1.0, 0.99, 1.0, 1.0, 1.0, 0.95, 0.81, 0.69, 0.59, 0.59, 0.54, 0.61, 0.64, 0.34, 0.82, 0.89, 0.56, 0.69, 0.51, 0.52, 0.49, 0.8, 0.4, 0.75, 0.78, 0.79, 0.9, 0.99, 1.0, 0.99, 1.0, 1.0, 1.0, 1.0, 1.0, 0.99, 0.97, 0.99, 0.99, 0.99, 0.97, 0.99, 0.95, 0.92, 0.97, 0.88, 1.0, 1.0, 0.92, 1.0, 0.94, 1.0, 1.0, 0.85, 1.0, 0.75, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 0.95, 1.0, 0.95, 1.0, 0.83, 0.99, 0.89, 0.99, 0.94, 0.91, 0.95, 0.92, 1.0, 0.99, 1.0, 1.0, 1.0, 1.0, 0.99, 1.0, 0.99, 1.0, 1.0, 0.87, 1.0, 0.89, 0.92, 0.86, 0.9, 0.84, 0.98, 0.92, 0.95, 0.95, 0.89, 0.94, 0.96, 1.0, 0.96, 1.0, 1.0, 0.95, 1.0, 0.96, 1.0, 1.0, 1.0, 0.98, 0.97, 0.99, 0.92, 1.0, 1.0, 0.97, 1.0, 0.95, 1.0, 1.0, 0.94, 1.0, 0.91, 1.0, 0.9, 0.82, 0.91, 0.86, 1.0, 1.0, 1.0, 1.0, 1.0, 0.97, 1.0, 0.97, 1.0, 0.99, 1.0, 0.96, 0.7, 0.93, 0.79, 0.91, 0.9, 0.97, 0.94, 1.0, 0.87, 0.99, 0.64, 0.89, 0.85, 0.75, 0.93, 0.92, 0.98, 0.95, 1.0, 0.96, 1.0, 1.0, 1.0, 0.99, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 0.98, 1.0, 0.95, 0.99, 1.0, 0.86, 0.92, 0.85, 0.89, 0.98, 1.0, 1.0, 0.93, 0.99, 0.87, 0.79, 0.94, 0.74, 0.99, 0.89, 1.0, 0.96, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 0.99, 0.99, 0.69, 1.0, 0.99, 0.93, 0.99, 0.86, 0.99, 0.92, 0.96, 0.96, 0.9, 0.98, 0.81, 0.71, 0.91, 0.87, 0.78, 0.79, 0.83, 0.8, 0.89, 0.94, 0.96, 0.96, 0.91, 0.99, 0.99]
null
Component of an E-cadherin/ catenin adhesion complex composed of at least E-cadherin/CDH1, beta-catenin/CTNNB1 or gamma-catenin/JUP, and potentially alpha-catenin/CTNNA1. Forms a ternary complex composed of ADAM10, CADH1 and EPHA4,
null
null
KLRG1, SPEF1, DLGAP5, AJAP1, RAPGEF2, RAB8B, PIP5K1C, PKP2, TRPV4, CTNNB1, CAV1, DDR1, TBC1D2, CTNNA1, JUP, CTNND1, PSEN1, LIMA1, CDH1, JUP, ADAM10, CADH1 , EPHA4,
null
null
null
null
Homodimer
null
79.91949
0.474025
55.445307
0.80143
732
P12830
Q15468
null
degron_data
CDH1
MGPWSRSLSALLLLLQVSSWLCQEPEPCHPGFDAESYTFTVPRRHLERGRVLGRVNFEDCTGRQRTAYFSLDTRFKVGTDGVITVKRPLRFHNPQIHFLVYAWDSTYRKFSTKVTLNTVGHHHRPPPHQASVSGIQAELLTFPNSSPGLRRQKRDWVIPPISCPENEKGPFPKNLVQIKSNKDKEGKVFYSITGQGADTPPVGVFIIERETGWLKVTEPLDRERIATYTLFSHAVSSNGNAVEDPMEILITVTDQNDNKPEFTQEVFKGSVMEGALPGTSVMEVTATDADDDVNTYNAAIAYTILSQDPELPDKNMFTINRNTGVISVVTTGLDRESFPTYTLVVQAADLQGEGLSTTATAVITVTDTNDNPPIFNPTTYKGQVPENEANVVITTLKVTDADAPNTPAWEAVYTILNDDGGQFVVTTNPVNNDGILKTAKGLDFEAKQQYILHVAVTNVVPFEVSLTTSTATVTVDVLDVNEAPIFVPPEKRVEVSEDFGVGQEITSYTAQEPDTFMEQKITYRIWRDTANWLEINPDTGAISTRAELDREDFEHVKNSTYTALIIATDNGSPVATGTGTLLLILSDVNDNAPIPEPRTIFFCERNPKPQVINIIDADLPPNTSPFTAELTHGASANWTIQYNDPTQESIILKPKMALEVGDYKINLKLMDNQNKDQVTTLEVSVCDCEGAAGVCRKAQPVEAGLQIPAILGILGGILALLILILLLLLFLRRRAVVKEPLLPPEDDTRDNVYYYDEEGGGEEDQDFDLSQLHRGLDARPEVTRNDVAPTLMSVPRYLPRPANPDEIGNFIDENLKAADTDPTAPPYDSLLVFDYEGSGSEAASLSSLNSSESDKDQDYDYLNEWGNRFKKLADMYGGGEDD
Homo sapiens
Cell junction, adherens junction, Cell membrane, Endosome, Golgi apparatus, trans-Golgi network, Cytoplasm, Cell junction, desmosome
Tissue enhanced (parathyroid)
{'Ciliated cells': '119.1', 'Basal respiratory cells': '71.1', 'Club cells': '97.3', 'Ionocytes': '81.0', 'Mucus glandular cells': '155.0', 'Serous glandular cells': '67.8', 'Gastric mucus-secreting cells': '133.2', 'Proximal enterocytes': '140.9', 'Paneth cells': '125.1', 'Distal enterocytes': '307.5', 'Intestinal goblet cells': '173.5', 'Exocrine glandular cells': '-0.605', 'Basal prostatic cells': '68.3', 'Prostatic glandular cells': '186.7', 'Breast glandular cells': '0.773', 'Breast myoepithelial cells': '0.700', 'Glandular and luminal cells': '313.0', 'Secretory cells': '82.3', 'Basal keratinocytes': '102.5', 'Suprabasal keratinocytes': '162.6', 'Basal squamous epithelial cells': '51.0', 'Squamous epithelial cells': '106.9', 'Alveolar cells type 1': '0.437', 'Alveolar cells type 2': '0.706', 'Salivary duct cells': '95.9', 'Ductal cells': '0.541', 'Hepatocytes': '0.600', 'Cholangiocytes': '129.7', 'Proximal tubular cells': '0.042', 'Distal tubular cells': '0.0', 'Collecting duct cells': '143.9', 'Mesothelial cells': '0.799', 'Sertoli cells': '0.252', 'Granulosa cells': '12.9', 'Enteroendocrine cells': '92.4', 'Pancreatic endocrine cells': '78.1', 'Leydig cells': '0.264', 'Excitatory neurons': '0.7', 'Inhibitory neurons': '1.3', 'Cone photoreceptor cells': '0.0', 'Rod photoreceptor cells': '0.0', 'Bipolar cells': '0.2', 'Horizontal cells': '0.6', 'Astrocytes': '0.6', 'Oligodendrocyte precursor cells': '0.5', 'Oligodendrocytes': '29.9', 'Microglial cells': '0.9', 'Muller glia cells': '0.1', 'Schwann cells': '0.131', 'Spermatogonia': '0.392', 'Spermatocytes': '0.193', 'Early spermatids': '-0.217', 'Late spermatids': '-0.290', 'Oocytes': '16.9', 'Cytotrophoblasts': '119.2', 'Syncytiotrophoblasts': '45.0', 'Extravillous trophoblasts': '24.9', 'Endothelial cells': '6.1', 'Lymphatic endothelial cells': '0.4', 'Cardiomyocytes': '0.135', 'Skeletal myocytes': '0.107', 'Smooth muscle cells': '5.8', 'Adipocytes': '2.1', 'Melanocytes': '0.335', 'Fibroblasts': '6.5', 'Peritubular cells': '0.210', 'Endometrial stromal cells': '27.7', 'Ovarian stromal cells': '0.7', 'Undifferentiated cells': '101.6', 'T-cells': '2.9', 'B-cells': '4.4', 'Plasma cells': '6.1', 'Nk-cells': '0.0', 'Granulocytes': '8.4', 'Monocytes': '0.0', 'Macrophages': '6.0', 'Hofbauer cells': '4.3', 'Kupffer cells': '1.0', 'Dendritic cells': '5.9', 'Langerhans cells': '0.304', 'Erythroid cells': '0.036', 'Adipocytes (Subcutaneous)': '-0.081', 'Adipocytes (Visceral)': '-0.209', 'Breast glandular cells (progenitors)': '0.538', 'Adipocytes (Breast)': '-0.689', 'Colon enterocytes': '0.790', 'Colon enteroendocrine cells': '0.112', 'Enteric glia cells': '-0.048', 'Mitotic cells (Colon)': '0.299', 'Mitotic cells (Heart)': '0.120', 'Podocytes': '-0.118', 'Ascending Loop of Henle cells': '0.475', 'Intercalated cells': '0.212', 'Cholangiocyte': '0.090', 'NK-cells (Liver)': '-0.005', 'Respiratory ciliated cells': '-0.012', 'Mitotic cells (Lung)': '0.071', 'NK-cells (Lung)': '-0.266', 'B-cells (Lung)': '-0.296', 'Alpha cells': '0.270', 'Beta cells': '0.152', 'Prostate glandular cells': '0.764', 'Prostate basal glandular cells': '0.540', 'Urothelial cells': '0.205', 'Keratinocyte (other)': '0.510', 'Keratinocyte (granular)': '0.055', 'Hair cortex cells': '0.080', 'Inner root sheath cells': '0.131', 'Outer root sheath cells': '0.175', 'Sebaceous gland cells': '0.156', 'Eccrine sweat gland cells': '-0.207', 'Adipocytes (Skin)': '-0.244', 'Mitotic cells (Skin)': '0.442', 'Parietal cells': '0.654', 'Chief cells': '0.649', 'Gastric mucous cells': '0.781', 'Gastric enteroendocrine cells': '0.590', 'Mitotic cells (Stomach)': '0.445', 'Parafollicular cells': '0.173', 'Thyroid glandular cells': '0.865', 'Mitotic cells (Thyroid)': '-0.081', 'Adrenal cortex cells': '0.051', 'Adrenal medulla cells': '0.087', 'Mitotic cells (Adrenal gland)': '0.072', 'Minor salivary glandular cells': '0.371', 'Minor salivary gland ductal cells': '-0.142', 'Minor salivary gland basal cells': '0.582', 'Mitotic cells (Minor salivary gland)': '0.567', 'Adipocytes (Minor salivary gland)': '0.050', 'Somatotropes': '0.121', 'Lactotropes': '0.322', 'Gonadotropes': '0.330', 'Corticotropes': '0.180', 'Thyrotropes': '0.496', 'Undifferentiated cells (Pituitary gland)': '-0.108', 'Mitotic cells (Spleen)': '-0.228', 'Platelets': '-0.050', 'Erythrocytes': '-0.158', 'Hematopoietic stem cells': '-0.211', 'B-cells (Spleen)': '0.266', 'NK-cells (Spleen)': '0.309', 'Amygdala excitatory': '1.0', 'Cerebellar inhibitory': '0.9', 'Cge interneuron': '0.7', 'Deep-layer corticothalamic and 6b': '1.5', 'Deep-layer intratelencephalic': '0.7', 'Deep-layer near-projecting': '0.7', 'Eccentric medium spiny neuron': '0.6', 'Hippocampal ca1-3': '1.9', 'Hippocampal ca4': '1.2', 'Hippocampal dentate gyrus': '1.1', 'Lamp5-lhx6 and chandelier': '0.5', 'Lower rhombic lip': '0.8', 'Mammillary body': '0.6', 'Medium spiny neuron': '0.7', 'Mge interneuron': '1.7', 'Midbrain-derived inhibitory': '0.7', 'Miscellaneous': '0.9', 'Splatter': '3.8', 'Thalamic excitatory': '0.5', 'Upper rhombic lip': '0.8', 'Upper-layer intratelencephalic': '0.6', 'Astrocyte': '4.4', 'Bergmann glia': '0.2', 'Central nervous system macrophage': '0.6', 'Choroid plexus epithelial cell': '52.1', 'Committed oligodendrocyte precursor': '41.5', 'Ependymal cell': '4.8', 'Oligodendrocyte': '53.1', 'Oligodendrocyte precursor cell': '2.4', 'Endothelial cell': '0.7', 'Pericyte': '0.3', 'Vascular associated smooth muscle cell': '0.0', 'Fibroblast': '17.4', 'Leukocyte': '1.1', 'Basophil': '0.0', 'Eosinophil': '0.0', 'Neutrophil': '0.0', 'Classical monocyte': '0.0', 'Non-classical monocyte': '0.0', 'Intermediate monocyte': '0.0', 'T-reg': '2.3', 'GdT-cell': '0.0', 'MAIT T-cell': '0.0', 'Memory CD4 T-cell': '0.0', 'Naive CD4 T-cell': '0.1', 'Memory CD8 T-cell': '0.2', 'Naive CD8 T-cell': '0.3', 'Memory B-cell': '0.0', 'Naive B-cell': '0.1', 'Plasmacytoid DC': '46.6', 'Myeloid DC': '8.5', 'NK-cell': '0.1', 'Total PBMC': '0.7', 'Vd2 gdTCR': '0.0', 'Memory CD4 T-cell Th1\\/Th17': '0.1', 'Memory CD4 T-cell Th17': '0.2', 'Memory CD4 T-cell Th2': '2.9', 'Non-Vd2 gdTCR': '0.1', 'Memory CD4 T-cell Th1': '0.3', 'Memory CD4 T-cell TFH': '0.5', 'Terminal effector memory CD4 T-cell': '0.0', 'Central memory CD8 T-cell': '4.8', 'Effector memory CD8 T-cell': '0.0', 'Terminal effector memory CD8 T-cell': '0.6', 'Non-switched memory B-cell': '0.0', 'Plasmablast': '3.3', 'Switched memory B-cell': '0.0', 'Exhausted memory B-cell': '0.7', 'Progenitor cell': '2.3', 'Memory T-reg': '1.3', 'Naive CD4 T-cell activated': '0.3', 'Naive CD8 T-cell activated': '0.6', 'Naive T-reg': '0.1'}
1O6S, 2O72, 2OMT, 2OMU, 2OMV, 2OMX, 2OMY, 2OMZ, 3FF7, 3FF8, 3L6X, 3L6Y, 4ZT1, 4ZTE, 6CXY, 6OLE, 6OLF, 6OLG, 6VEL, 7STZ, 8H62
{'Adipose Tissue': 1.2125261088039867, 'Adrenal Gland': 0.1914223992248062, 'Bladder': 39.2033519047619, 'Blood': 1.340954264800861, 'Blood Vessel': 0.3121561692883895, 'Brain': 0.8550442199091597, 'Breast': 38.54918344226579, 'Cervix Uteri': 23.539115789473684, 'Colon': 43.41292142490372, 'Esophagus': 53.97513367404844, 'Fallopian Tube': 14.900277777777776, 'Heart': 0.119140469221835, 'Kidney': 25.040449438202245, 'Liver': 26.60802654867257, 'Lung': 35.447986366782004, 'Muscle': 0.1378936151930261, 'Nerve': 17.518468982229404, 'Ovary': 3.6515122222222223, 'Pancreas': 56.89676829268293, 'Pituitary': 24.68741660777385, 'Prostate': 61.279967346938776, 'Salivary Gland': 92.01685185185184, 'Skin': 79.77571720232172, 'Small Intestine': 71.7519320855615, 'Spleen': 10.061029045643156, 'Stomach': 58.07813805013927, 'Testis': 0.8144204986149585, 'Thyroid': 135.176797856049, 'Uterus': 1.442593943661972, 'Vagina': 86.52345512820513}
STIL
MEPIYPFARPQMNTRFPSSRMVPFHFPPSKCALWNPTPTGDFIYLHLSYYRNPKLVVTEKTIRLAYRHAKQNKKNSSCFLLGSLTADEDEEGVTLTVDRFDPGREVPECLEITPTASLPGDFLIPCKVHTQELCSREMIVHSVDDFSSALKALQCHICSKDSLDCGKLLSLRVHITSRESLDSVEFDLHWAAVTLANNFKCTPVKPIPIIPTALARNLSSNLNISQVQGTYKYGYLTMDETRKLLLLLESDPKVYSLPLVGIWLSGITHIYSPQVWACCLRYIFNSSVQERVFSESGNFIIVLYSMTHKEPEFYECFPCDGKIPDFRFQLLTSKETLHLFKNVEPPDKNPIRCELSAESQNAETEFFSKASKNFSIKRSSQKLSSGKMPIHDHDSGVEDEDFSPRPIPSPHPVSQKISKIQPSVPELSLVLDGNFIESNPLPTPLEMVNNENPPLINHLEHLKPLQPQLYDEKHSPEVEAGEPSLRGIPNQLNQDKPALLRHCKVRQPPAYKKGNPHTRNSIKPSSHNGPSHDIFEKLQTVSAGNVQNEEYPIRPSTLNSRQSSLAPQSQPHDFVFSPHNSGRPMELQIPTPPLPSYCSTNVCRCCQHHSHIQYSPLNSWQGANTVGSIQDVQSEALQKHSLFHPSGCPALYCNAFCSSSSPIALRPQGDMGSCSPHSNIEPSPVARPPSHMDLCNPQPCTVCMHTPKTESDNGMMGLSPDAYRFLTEQDRQLRLLQAQIQRLLEAQSLMPCSPKTTAVEDTVQAGRQMELVSVEAQSSPGLHMRKGVSIAVSTGASLFWNAAGEDQEPDSQMKQDDTKISSEDMNFSVDINNEVTSLPGSASSLKAVDIPSFEESNIAVEEEFNQPLSVSNSSLVVRKEPDVPVFFPSGQLAESVSMCLQTGPTGGASNNSETSEEPKIEHVMQPLLHQPSDNQKIYQDLLGQVNHLLNSSSKETEQPSTKAVIISHECTRTQNVYHTKKKTHHSRLVDKDCVLNATLKQLRSLGVKIDSPTKVKKNAHNVDHASVLACISPEAVISGLNCMSFANVGMSGLSPNGVDLSMEANAIALKYLNENQLSQLSVTRSNQNNCDPFSLLHINTDRSTVGLSLISPNNMSFATKKYMKRYGLLQSSDNSEDEEEPPDNADSKSEYLLNQNLRSIPEQLGGQKEPSKNDHEIINCSNCESVGTNADTPVLRNITNEVLQTKAKQQLTEKPAFLVKNLKPSPAVNLRTGKAEFTQHPEKENEGDITIFPESLQPSETLKQMNSMNSVGTFLDVKRLRQLPKLF
Homo sapiens
Cytoplasm, cytosol, Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriole, Cytoplasm, cell cortex
Tissue enhanced (bone marrow, lymphoid tissue)
{'Ciliated cells': '6.1', 'Basal respiratory cells': '1.7', 'Club cells': '2.0', 'Ionocytes': '2.2', 'Mucus glandular cells': '5.8', 'Serous glandular cells': '3.3', 'Gastric mucus-secreting cells': '4.1', 'Proximal enterocytes': '1.3', 'Paneth cells': '1.6', 'Distal enterocytes': '3.9', 'Intestinal goblet cells': '4.7', 'Exocrine glandular cells': '-0.580', 'Basal prostatic cells': '0.6', 'Prostatic glandular cells': '1.2', 'Breast glandular cells': '0.533', 'Breast myoepithelial cells': '0.393', 'Glandular and luminal cells': '12.1', 'Secretory cells': '1.1', 'Basal keratinocytes': '3.0', 'Suprabasal keratinocytes': '2.5', 'Basal squamous epithelial cells': '2.2', 'Squamous epithelial cells': '5.5', 'Alveolar cells type 1': '-0.234', 'Alveolar cells type 2': '0.152', 'Salivary duct cells': '3.0', 'Ductal cells': '0.637', 'Hepatocytes': '0.347', 'Cholangiocytes': '0.0', 'Proximal tubular cells': '0.279', 'Distal tubular cells': '0.0', 'Collecting duct cells': '0.0', 'Mesothelial cells': '-0.075', 'Sertoli cells': '-0.106', 'Granulosa cells': '1.7', 'Enteroendocrine cells': '1.1', 'Pancreatic endocrine cells': '3.4', 'Leydig cells': '-0.087', 'Excitatory neurons': '4.9', 'Inhibitory neurons': '3.8', 'Cone photoreceptor cells': '0.0', 'Rod photoreceptor cells': '1.1', 'Bipolar cells': '0.4', 'Horizontal cells': '1.3', 'Astrocytes': '1.9', 'Oligodendrocyte precursor cells': '1.9', 'Oligodendrocytes': '4.5', 'Microglial cells': '0.0', 'Muller glia cells': '0.4', 'Schwann cells': '0.101', 'Spermatogonia': '0.308', 'Spermatocytes': '0.794', 'Early spermatids': '0.443', 'Late spermatids': '0.025', 'Oocytes': '1.5', 'Cytotrophoblasts': '2.5', 'Syncytiotrophoblasts': '0.8', 'Extravillous trophoblasts': '4.3', 'Endothelial cells': '1.3', 'Lymphatic endothelial cells': '6.0', 'Cardiomyocytes': '0.354', 'Skeletal myocytes': '-0.023', 'Smooth muscle cells': '1.1', 'Adipocytes': '1.2', 'Melanocytes': '0.348', 'Fibroblasts': '1.0', 'Peritubular cells': '-0.098', 'Endometrial stromal cells': '2.6', 'Ovarian stromal cells': '0.4', 'Undifferentiated cells': '9.6', 'T-cells': '2.7', 'B-cells': '2.4', 'Plasma cells': '9.5', 'Nk-cells': '1.6', 'Granulocytes': '0.3', 'Monocytes': '0.9', 'Macrophages': '2.6', 'Hofbauer cells': '2.5', 'Kupffer cells': '2.0', 'Dendritic cells': '1.6', 'Langerhans cells': '0.340', 'Erythroid cells': '-0.128', 'Adipocytes (Subcutaneous)': '0.098', 'Adipocytes (Visceral)': '0.066', 'Breast glandular cells (progenitors)': '0.430', 'Adipocytes (Breast)': '-0.438', 'Colon enterocytes': '0.454', 'Colon enteroendocrine cells': '0.025', 'Enteric glia cells': '-0.146', 'Mitotic cells (Colon)': '0.570', 'Mitotic cells (Heart)': '0.653', 'Podocytes': '-0.273', 'Ascending Loop of Henle cells': '0.351', 'Intercalated cells': '-0.213', 'Cholangiocyte': '0.326', 'NK-cells (Liver)': '-0.225', 'Respiratory ciliated cells': '0.142', 'Mitotic cells (Lung)': '0.705', 'NK-cells (Lung)': '-0.146', 'B-cells (Lung)': '-0.029', 'Alpha cells': '0.334', 'Beta cells': '0.246', 'Prostate glandular cells': '0.421', 'Prostate basal glandular cells': '0.450', 'Urothelial cells': '0.255', 'Keratinocyte (other)': '0.446', 'Keratinocyte (granular)': '-0.069', 'Hair cortex cells': '-0.168', 'Inner root sheath cells': '-0.064', 'Outer root sheath cells': '0.044', 'Sebaceous gland cells': '0.111', 'Eccrine sweat gland cells': '-0.211', 'Adipocytes (Skin)': '-0.371', 'Mitotic cells (Skin)': '0.624', 'Parietal cells': '0.239', 'Chief cells': '0.170', 'Gastric mucous cells': '0.662', 'Gastric enteroendocrine cells': '0.307', 'Mitotic cells (Stomach)': '0.832', 'Parafollicular cells': '0.014', 'Thyroid glandular cells': '0.140', 'Mitotic cells (Thyroid)': '0.343', 'Adrenal cortex cells': '0.364', 'Adrenal medulla cells': '0.085', 'Mitotic cells (Adrenal gland)': '0.751', 'Minor salivary glandular cells': '0.244', 'Minor salivary gland ductal cells': '0.100', 'Minor salivary gland basal cells': '-0.021', 'Mitotic cells (Minor salivary gland)': '0.070', 'Adipocytes (Minor salivary gland)': '-0.282', 'Somatotropes': '-0.092', 'Lactotropes': '-0.241', 'Gonadotropes': '-0.016', 'Corticotropes': '-0.256', 'Thyrotropes': '-0.094', 'Undifferentiated cells (Pituitary gland)': '0.452', 'Mitotic cells (Spleen)': '0.831', 'Platelets': '0.137', 'Erythrocytes': '0.313', 'Hematopoietic stem cells': '0.223', 'B-cells (Spleen)': '-0.011', 'NK-cells (Spleen)': '-0.033', 'Amygdala excitatory': '7.1', 'Cerebellar inhibitory': '4.8', 'Cge interneuron': '3.7', 'Deep-layer corticothalamic and 6b': '6.9', 'Deep-layer intratelencephalic': '6.4', 'Deep-layer near-projecting': '6.9', 'Eccentric medium spiny neuron': '5.9', 'Hippocampal ca1-3': '6.5', 'Hippocampal ca4': '7.5', 'Hippocampal dentate gyrus': '3.9', 'Lamp5-lhx6 and chandelier': '2.6', 'Lower rhombic lip': '6.1', 'Mammillary body': '7.0', 'Medium spiny neuron': '6.0', 'Mge interneuron': '5.3', 'Midbrain-derived inhibitory': '6.6', 'Miscellaneous': '5.8', 'Splatter': '4.9', 'Thalamic excitatory': '6.7', 'Upper rhombic lip': '1.7', 'Upper-layer intratelencephalic': '6.0', 'Astrocyte': '6.6', 'Bergmann glia': '5.1', 'Central nervous system macrophage': '4.0', 'Choroid plexus epithelial cell': '2.1', 'Committed oligodendrocyte precursor': '2.3', 'Ependymal cell': '5.9', 'Oligodendrocyte': '4.3', 'Oligodendrocyte precursor cell': '2.2', 'Endothelial cell': '6.2', 'Pericyte': '1.5', 'Vascular associated smooth muscle cell': '2.3', 'Fibroblast': '2.0', 'Leukocyte': '2.7', 'Basophil': '0.9', 'Eosinophil': '0.2', 'Neutrophil': '1.4', 'Classical monocyte': '0.9', 'Non-classical monocyte': '1.1', 'Intermediate monocyte': '0.7', 'T-reg': '2.2', 'GdT-cell': '0.1', 'MAIT T-cell': '0.5', 'Memory CD4 T-cell': '0.1', 'Naive CD4 T-cell': '2.5', 'Memory CD8 T-cell': '0.2', 'Naive CD8 T-cell': '1.9', 'Memory B-cell': '0.3', 'Naive B-cell': '2.1', 'Plasmacytoid DC': '3.0', 'Myeloid DC': '1.1', 'NK-cell': '2.1', 'Total PBMC': '1.4', 'Vd2 gdTCR': '0.5', 'Memory CD4 T-cell Th1\\/Th17': '2.2', 'Memory CD4 T-cell Th17': '2.2', 'Memory CD4 T-cell Th2': '2.8', 'Non-Vd2 gdTCR': '0.9', 'Memory CD4 T-cell Th1': '2.5', 'Memory CD4 T-cell TFH': '2.0', 'Terminal effector memory CD4 T-cell': '1.5', 'Central memory CD8 T-cell': '0.9', 'Effector memory CD8 T-cell': '2.1', 'Terminal effector memory CD8 T-cell': '0.6', 'Non-switched memory B-cell': '1.0', 'Plasmablast': '8.1', 'Switched memory B-cell': '0.9', 'Exhausted memory B-cell': '4.5', 'Progenitor cell': '2.2', 'Memory T-reg': '3.2', 'Naive CD4 T-cell activated': '5.8', 'Naive CD8 T-cell activated': '3.8', 'Naive T-reg': '2.0'}
4YYP, 5LHW, 5LHZ, 8OYK, 8OYL
{'Adipose Tissue': 0.9901666943521594, 'Adrenal Gland': 0.7493770930232558, 'Bladder': 0.9425142857142856, 'Blood': 4.488175009687837, 'Blood Vessel': 0.5636820149812735, 'Brain': 0.7385426154428463, 'Breast': 1.2491721132897604, 'Cervix Uteri': 1.0014105263157895, 'Colon': 1.9123311553273428, 'Esophagus': 1.745949750865052, 'Fallopian Tube': 0.8377, 'Heart': 0.2820289326364692, 'Kidney': 0.7304966292134831, 'Liver': 0.5065336283185841, 'Lung': 1.49800830449827, 'Muscle': 0.2364307222914072, 'Nerve': 0.9094174474959612, 'Ovary': 1.0490244444444443, 'Pancreas': 0.4592714634146341, 'Pituitary': 0.7898918727915194, 'Prostate': 1.599735020408163, 'Salivary Gland': 2.6179135802469133, 'Skin': 4.266187396351576, 'Small Intestine': 3.0804090909090913, 'Spleen': 2.566144813278008, 'Stomach': 1.2696304456824512, 'Testis': 9.933952908587258, 'Thyroid': 1.0626485451761103, 'Uterus': 0.8795042253521127, 'Vagina': 2.0071641025641025}
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0.87, 0.77, 0.96, 0.94, 0.69, 0.75, 0.65, 0.59, 0.48, 0.79, 0.56, 0.52, 0.6, 0.5, 0.49, 0.24, 0.69, 0.87, 0.8, 0.35, 0.56, 0.69, 0.66, 0.39, 0.29, 0.43, 0.61, 0.58, 0.64, 0.5, 0.73, 0.89, 0.72, 0.75, 0.95, 0.98, 1.0, 0.97, 0.93, 0.99, 1.0, 0.89, 0.89, 0.95, 0.85, 1.0, 0.93, 1.0, 1.0, 0.99, 1.0, 0.82, 1.0, 0.8, 0.78, 0.98, 0.82, 0.64, 0.56, 0.55, 0.86, 0.82, 0.17, 0.52, 0.78, 0.7, 0.41, 0.36, 0.61, 0.56, 0.23, 0.64, 0.81, 0.53, 0.71, 0.64, 0.34, 0.96, 0.91, 0.94, 0.89, 1.0, 0.88, 1.0, 0.97, 1.0, 0.95, 0.96, 0.91, 0.92, 0.94, 0.97, 1.0, 1.0, 1.0, 1.0, 0.86, 0.99, 0.95, 0.99, 1.0, 0.96, 1.0, 0.9, 1.0, 0.95, 0.97, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 0.99, 1.0, 0.99, 1.0, 0.98, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 0.99, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 0.87, 1.0, 1.0, 0.96, 1.0, 0.97, 0.99, 1.0, 0.73, 1.0, 0.81, 1.0, 0.97, 1.0, 0.98, 0.95, 0.97, 0.97, 0.99, 1.0, 0.97, 0.94, 0.86, 0.85, 0.9, 0.97, 0.98, 0.98, 0.99, 0.97, 0.95, 0.86, 0.93, 0.92, 0.99, 0.99, 0.94, 0.95, 0.92, 0.95, 0.93, 0.96, 0.94, 0.92, 1.0, 0.99, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 0.98, 0.99, 0.96, 0.99, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 0.85, 1.0, 0.89, 0.91, 0.85, 0.78, 0.99, 0.89, 0.79, 0.44, 0.57, 0.75, 0.71, 0.48, 0.84, 0.75, 0.75, 0.87, 0.92, 0.93, 0.95]
null
Component of an E-cadherin/ catenin adhesion complex composed of at least E-cadherin/CDH1, beta-catenin/CTNNB1 or gamma-catenin/JUP, and potentially alpha-catenin/CTNNA1. Forms a ternary complex composed of ADAM10, CADH1 and EPHA4,
null
null
KLRG1, SPEF1, DLGAP5, AJAP1, RAPGEF2, RAB8B, PIP5K1C, PKP2, TRPV4, CTNNB1, CAV1, DDR1, TBC1D2, CTNNA1, JUP, CTNND1, PSEN1, LIMA1, CDH1, JUP, ADAM10, CADH1 , EPHA4,
null
null
null
null
Homodimer
null
79.91949
0.474025
53.109953
0.722347
288
P12830
Q15468-2
null
degron_data
CDH1
MGPWSRSLSALLLLLQVSSWLCQEPEPCHPGFDAESYTFTVPRRHLERGRVLGRVNFEDCTGRQRTAYFSLDTRFKVGTDGVITVKRPLRFHNPQIHFLVYAWDSTYRKFSTKVTLNTVGHHHRPPPHQASVSGIQAELLTFPNSSPGLRRQKRDWVIPPISCPENEKGPFPKNLVQIKSNKDKEGKVFYSITGQGADTPPVGVFIIERETGWLKVTEPLDRERIATYTLFSHAVSSNGNAVEDPMEILITVTDQNDNKPEFTQEVFKGSVMEGALPGTSVMEVTATDADDDVNTYNAAIAYTILSQDPELPDKNMFTINRNTGVISVVTTGLDRESFPTYTLVVQAADLQGEGLSTTATAVITVTDTNDNPPIFNPTTYKGQVPENEANVVITTLKVTDADAPNTPAWEAVYTILNDDGGQFVVTTNPVNNDGILKTAKGLDFEAKQQYILHVAVTNVVPFEVSLTTSTATVTVDVLDVNEAPIFVPPEKRVEVSEDFGVGQEITSYTAQEPDTFMEQKITYRIWRDTANWLEINPDTGAISTRAELDREDFEHVKNSTYTALIIATDNGSPVATGTGTLLLILSDVNDNAPIPEPRTIFFCERNPKPQVINIIDADLPPNTSPFTAELTHGASANWTIQYNDPTQESIILKPKMALEVGDYKINLKLMDNQNKDQVTTLEVSVCDCEGAAGVCRKAQPVEAGLQIPAILGILGGILALLILILLLLLFLRRRAVVKEPLLPPEDDTRDNVYYYDEEGGGEEDQDFDLSQLHRGLDARPEVTRNDVAPTLMSVPRYLPRPANPDEIGNFIDENLKAADTDPTAPPYDSLLVFDYEGSGSEAASLSSLNSSESDKDQDYDYLNEWGNRFKKLADMYGGGEDD
Homo sapiens
Cell junction, adherens junction, Cell membrane, Endosome, Golgi apparatus, trans-Golgi network, Cytoplasm, Cell junction, desmosome
Tissue enhanced (parathyroid)
{'Ciliated cells': '119.1', 'Basal respiratory cells': '71.1', 'Club cells': '97.3', 'Ionocytes': '81.0', 'Mucus glandular cells': '155.0', 'Serous glandular cells': '67.8', 'Gastric mucus-secreting cells': '133.2', 'Proximal enterocytes': '140.9', 'Paneth cells': '125.1', 'Distal enterocytes': '307.5', 'Intestinal goblet cells': '173.5', 'Exocrine glandular cells': '-0.605', 'Basal prostatic cells': '68.3', 'Prostatic glandular cells': '186.7', 'Breast glandular cells': '0.773', 'Breast myoepithelial cells': '0.700', 'Glandular and luminal cells': '313.0', 'Secretory cells': '82.3', 'Basal keratinocytes': '102.5', 'Suprabasal keratinocytes': '162.6', 'Basal squamous epithelial cells': '51.0', 'Squamous epithelial cells': '106.9', 'Alveolar cells type 1': '0.437', 'Alveolar cells type 2': '0.706', 'Salivary duct cells': '95.9', 'Ductal cells': '0.541', 'Hepatocytes': '0.600', 'Cholangiocytes': '129.7', 'Proximal tubular cells': '0.042', 'Distal tubular cells': '0.0', 'Collecting duct cells': '143.9', 'Mesothelial cells': '0.799', 'Sertoli cells': '0.252', 'Granulosa cells': '12.9', 'Enteroendocrine cells': '92.4', 'Pancreatic endocrine cells': '78.1', 'Leydig cells': '0.264', 'Excitatory neurons': '0.7', 'Inhibitory neurons': '1.3', 'Cone photoreceptor cells': '0.0', 'Rod photoreceptor cells': '0.0', 'Bipolar cells': '0.2', 'Horizontal cells': '0.6', 'Astrocytes': '0.6', 'Oligodendrocyte precursor cells': '0.5', 'Oligodendrocytes': '29.9', 'Microglial cells': '0.9', 'Muller glia cells': '0.1', 'Schwann cells': '0.131', 'Spermatogonia': '0.392', 'Spermatocytes': '0.193', 'Early spermatids': '-0.217', 'Late spermatids': '-0.290', 'Oocytes': '16.9', 'Cytotrophoblasts': '119.2', 'Syncytiotrophoblasts': '45.0', 'Extravillous trophoblasts': '24.9', 'Endothelial cells': '6.1', 'Lymphatic endothelial cells': '0.4', 'Cardiomyocytes': '0.135', 'Skeletal myocytes': '0.107', 'Smooth muscle cells': '5.8', 'Adipocytes': '2.1', 'Melanocytes': '0.335', 'Fibroblasts': '6.5', 'Peritubular cells': '0.210', 'Endometrial stromal cells': '27.7', 'Ovarian stromal cells': '0.7', 'Undifferentiated cells': '101.6', 'T-cells': '2.9', 'B-cells': '4.4', 'Plasma cells': '6.1', 'Nk-cells': '0.0', 'Granulocytes': '8.4', 'Monocytes': '0.0', 'Macrophages': '6.0', 'Hofbauer cells': '4.3', 'Kupffer cells': '1.0', 'Dendritic cells': '5.9', 'Langerhans cells': '0.304', 'Erythroid cells': '0.036', 'Adipocytes (Subcutaneous)': '-0.081', 'Adipocytes (Visceral)': '-0.209', 'Breast glandular cells (progenitors)': '0.538', 'Adipocytes (Breast)': '-0.689', 'Colon enterocytes': '0.790', 'Colon enteroendocrine cells': '0.112', 'Enteric glia cells': '-0.048', 'Mitotic cells (Colon)': '0.299', 'Mitotic cells (Heart)': '0.120', 'Podocytes': '-0.118', 'Ascending Loop of Henle cells': '0.475', 'Intercalated cells': '0.212', 'Cholangiocyte': '0.090', 'NK-cells (Liver)': '-0.005', 'Respiratory ciliated cells': '-0.012', 'Mitotic cells (Lung)': '0.071', 'NK-cells (Lung)': '-0.266', 'B-cells (Lung)': '-0.296', 'Alpha cells': '0.270', 'Beta cells': '0.152', 'Prostate glandular cells': '0.764', 'Prostate basal glandular cells': '0.540', 'Urothelial cells': '0.205', 'Keratinocyte (other)': '0.510', 'Keratinocyte (granular)': '0.055', 'Hair cortex cells': '0.080', 'Inner root sheath cells': '0.131', 'Outer root sheath cells': '0.175', 'Sebaceous gland cells': '0.156', 'Eccrine sweat gland cells': '-0.207', 'Adipocytes (Skin)': '-0.244', 'Mitotic cells (Skin)': '0.442', 'Parietal cells': '0.654', 'Chief cells': '0.649', 'Gastric mucous cells': '0.781', 'Gastric enteroendocrine cells': '0.590', 'Mitotic cells (Stomach)': '0.445', 'Parafollicular cells': '0.173', 'Thyroid glandular cells': '0.865', 'Mitotic cells (Thyroid)': '-0.081', 'Adrenal cortex cells': '0.051', 'Adrenal medulla cells': '0.087', 'Mitotic cells (Adrenal gland)': '0.072', 'Minor salivary glandular cells': '0.371', 'Minor salivary gland ductal cells': '-0.142', 'Minor salivary gland basal cells': '0.582', 'Mitotic cells (Minor salivary gland)': '0.567', 'Adipocytes (Minor salivary gland)': '0.050', 'Somatotropes': '0.121', 'Lactotropes': '0.322', 'Gonadotropes': '0.330', 'Corticotropes': '0.180', 'Thyrotropes': '0.496', 'Undifferentiated cells (Pituitary gland)': '-0.108', 'Mitotic cells (Spleen)': '-0.228', 'Platelets': '-0.050', 'Erythrocytes': '-0.158', 'Hematopoietic stem cells': '-0.211', 'B-cells (Spleen)': '0.266', 'NK-cells (Spleen)': '0.309', 'Amygdala excitatory': '1.0', 'Cerebellar inhibitory': '0.9', 'Cge interneuron': '0.7', 'Deep-layer corticothalamic and 6b': '1.5', 'Deep-layer intratelencephalic': '0.7', 'Deep-layer near-projecting': '0.7', 'Eccentric medium spiny neuron': '0.6', 'Hippocampal ca1-3': '1.9', 'Hippocampal ca4': '1.2', 'Hippocampal dentate gyrus': '1.1', 'Lamp5-lhx6 and chandelier': '0.5', 'Lower rhombic lip': '0.8', 'Mammillary body': '0.6', 'Medium spiny neuron': '0.7', 'Mge interneuron': '1.7', 'Midbrain-derived inhibitory': '0.7', 'Miscellaneous': '0.9', 'Splatter': '3.8', 'Thalamic excitatory': '0.5', 'Upper rhombic lip': '0.8', 'Upper-layer intratelencephalic': '0.6', 'Astrocyte': '4.4', 'Bergmann glia': '0.2', 'Central nervous system macrophage': '0.6', 'Choroid plexus epithelial cell': '52.1', 'Committed oligodendrocyte precursor': '41.5', 'Ependymal cell': '4.8', 'Oligodendrocyte': '53.1', 'Oligodendrocyte precursor cell': '2.4', 'Endothelial cell': '0.7', 'Pericyte': '0.3', 'Vascular associated smooth muscle cell': '0.0', 'Fibroblast': '17.4', 'Leukocyte': '1.1', 'Basophil': '0.0', 'Eosinophil': '0.0', 'Neutrophil': '0.0', 'Classical monocyte': '0.0', 'Non-classical monocyte': '0.0', 'Intermediate monocyte': '0.0', 'T-reg': '2.3', 'GdT-cell': '0.0', 'MAIT T-cell': '0.0', 'Memory CD4 T-cell': '0.0', 'Naive CD4 T-cell': '0.1', 'Memory CD8 T-cell': '0.2', 'Naive CD8 T-cell': '0.3', 'Memory B-cell': '0.0', 'Naive B-cell': '0.1', 'Plasmacytoid DC': '46.6', 'Myeloid DC': '8.5', 'NK-cell': '0.1', 'Total PBMC': '0.7', 'Vd2 gdTCR': '0.0', 'Memory CD4 T-cell Th1\\/Th17': '0.1', 'Memory CD4 T-cell Th17': '0.2', 'Memory CD4 T-cell Th2': '2.9', 'Non-Vd2 gdTCR': '0.1', 'Memory CD4 T-cell Th1': '0.3', 'Memory CD4 T-cell TFH': '0.5', 'Terminal effector memory CD4 T-cell': '0.0', 'Central memory CD8 T-cell': '4.8', 'Effector memory CD8 T-cell': '0.0', 'Terminal effector memory CD8 T-cell': '0.6', 'Non-switched memory B-cell': '0.0', 'Plasmablast': '3.3', 'Switched memory B-cell': '0.0', 'Exhausted memory B-cell': '0.7', 'Progenitor cell': '2.3', 'Memory T-reg': '1.3', 'Naive CD4 T-cell activated': '0.3', 'Naive CD8 T-cell activated': '0.6', 'Naive T-reg': '0.1'}
1O6S, 2O72, 2OMT, 2OMU, 2OMV, 2OMX, 2OMY, 2OMZ, 3FF7, 3FF8, 3L6X, 3L6Y, 4ZT1, 4ZTE, 6CXY, 6OLE, 6OLF, 6OLG, 6VEL, 7STZ, 8H62
{'Adipose Tissue': 1.2125261088039867, 'Adrenal Gland': 0.1914223992248062, 'Bladder': 39.2033519047619, 'Blood': 1.340954264800861, 'Blood Vessel': 0.3121561692883895, 'Brain': 0.8550442199091597, 'Breast': 38.54918344226579, 'Cervix Uteri': 23.539115789473684, 'Colon': 43.41292142490372, 'Esophagus': 53.97513367404844, 'Fallopian Tube': 14.900277777777776, 'Heart': 0.119140469221835, 'Kidney': 25.040449438202245, 'Liver': 26.60802654867257, 'Lung': 35.447986366782004, 'Muscle': 0.1378936151930261, 'Nerve': 17.518468982229404, 'Ovary': 3.6515122222222223, 'Pancreas': 56.89676829268293, 'Pituitary': 24.68741660777385, 'Prostate': 61.279967346938776, 'Salivary Gland': 92.01685185185184, 'Skin': 79.77571720232172, 'Small Intestine': 71.7519320855615, 'Spleen': 10.061029045643156, 'Stomach': 58.07813805013927, 'Testis': 0.8144204986149585, 'Thyroid': 135.176797856049, 'Uterus': 1.442593943661972, 'Vagina': 86.52345512820513}
STIL
MEPIYPFARPQMNTRFPSSRMVPFHFPPSKCALWNPTPTGDFIYLHLSYYRNPKLVVTEKTIRLAYRHAKQNKKNSSCFLLGSLTADEDEEGVTLTVDRFDPGREVPECLEITPTASLPGDFLIPCKVHTQELCSREMIVHSVDDFSSALKALQCHICSKDSLDCGKLLSLRVHITSRESLDSVEFDLHWAAVTLANNFKCTPVKPIPIIPTALARNLSSNLNISQVQGTYKYGYLTMDETRKLLLLLESDPKVYSLPLVGIWLSGITHIYSPQVWACCLRYIFNSSVQERVFSESGNFIIVLYSMTHKEPEFYECFPCDGKIPDFRFQLLTSKETLHLFKNVEPPDKNPIRCELSAESQNAETEFFSKASKNFSIKRSSQKLSSGKMPIHDHDSGVEDEDFSPRPIPSPHPVSQKISKIQPSVPELSLVLDGNFIESNPLPTPLEMVNNENPPLINHLEHLKPLQPQLYDEKHSPEVEAGEPSLRGIPNQLNQDKPALLRHCKVRQPPAYKKGNPHTRNSIKPSSHNGPSHDIFEKLQTVSAGNVQNEEYPIRPSTLNSRQSSLAPQSQPHDFVFSPHNSGRPMELQIPTPPLPSYCSTNVCRCCQHHSHIQYSPLNSWQGANTVGSIQDVQSEALQKHSLFHPSGCPALYCNAFCSSSSPIALRPQGDMGSCSPHSNIEPSPVARPPSHMDLCNPQPCTVCMHTPKTESDNGMMGLSPDAYRFLTEQDRQLRLLQAQIQRLLEAQSLMPCSPKTTAVEDTVQAGRQMELVSVEAQSSPGLHMRKGVSIAVSTGASLFWNAAGEDQEPDSQMKQDDTKISSEDMNFSVDINNEVTSLPGSASSLKAVDIPSFEESNIAVEEEFNQPLSVSNSSSLVVRKEPDVPVFFPSGQLAESVSMCLQTGPTGGASNNSETSEEPKIEHVMQPLLHQPSDNQKIYQDLLGQVNHLLNSSSKETEQPSTKAVIISHECTRTQNVYHTKKKTHHSRLVDKDCVLNATLKQLRSLGVKIDSPTKVKKNAHNVDHASVLACISPEAVISGLNCMSFANVGMSGLSPNGVDLSMEANAIALKYLNENQLSQLSVTRSNQNNCDPFSLLHINTDRSTVGLSLISPNNMSFATKKYMKRYGLLQSSDNSEDEEEPPDNADSKSEYLLNQNLRSIPEQLGGQKEPSKNDHEIINCSNCESVGTNADTPVLRNITNEVLQTKAKQQLTEKPAFLVKNLKPSPAVNLRTGKAEFTQHPEKENEGDITIFPESLQPSETLKQMNSMNSVGTFLDVKRLRQLPKLF
Homo sapiens
null
Not found
{}
null
{'Adipose Tissue': 0.9901666943521594, 'Adrenal Gland': 0.7493770930232558, 'Bladder': 0.9425142857142856, 'Blood': 4.488175009687837, 'Blood Vessel': 0.5636820149812735, 'Brain': 0.7385426154428463, 'Breast': 1.2491721132897604, 'Cervix Uteri': 1.0014105263157895, 'Colon': 1.9123311553273428, 'Esophagus': 1.745949750865052, 'Fallopian Tube': 0.8377, 'Heart': 0.2820289326364692, 'Kidney': 0.7304966292134831, 'Liver': 0.5065336283185841, 'Lung': 1.49800830449827, 'Muscle': 0.2364307222914072, 'Nerve': 0.9094174474959612, 'Ovary': 1.0490244444444443, 'Pancreas': 0.4592714634146341, 'Pituitary': 0.7898918727915194, 'Prostate': 1.599735020408163, 'Salivary Gland': 2.6179135802469133, 'Skin': 4.266187396351576, 'Small Intestine': 3.0804090909090913, 'Spleen': 2.566144813278008, 'Stomach': 1.2696304456824512, 'Testis': 9.933952908587258, 'Thyroid': 1.0626485451761103, 'Uterus': 0.8795042253521127, 'Vagina': 2.0071641025641025}
[39.93, 46.46, 52.9, 44.21, 41.4, 39.93, 35.91, 38.61, 36.44, 36.25, 34.86, 32.82, 32.01, 32.75, 31.69, 35.64, 36.35, 34.66, 33.32, 32.71, 35.01, 30.17, 37.05, 36.53, 48.19, 58.22, 64.94, 73.22, 78.33, 82.63, 85.79, 89.39, 87.89, 85.58, 83.93, 89.1, 89.27, 90.66, 87.86, 86.2, 82.97, 72.75, 73.3, 76.44, 82.38, 82.41, 79.49, 86.6, 76.32, 85.48, 88.69, 84.35, 87.75, 90.57, 88.72, 89.46, 87.48, 85.3, 81.72, 79.46, 77.26, 69.01, 67.1, 62.83, 67.71, 74.96, 82.95, 86.74, 86.35, 86.49, 84.6, 85.99, 85.64, 87.19, 89.23, 89.3, 90.62, 84.21, 85.42, 83.34, 84.28, 89.8, 89.78, 87.53, 87.64, 85.98, 81.31, 80.85, 78.74, 80.15, 70.67, 69.91, 72.91, 77.13, 83.26, 84.67, 90.36, 89.7, 92.74, 89.99, 92.55, 88.84, 87.15, 83.78, 78.78, 81.48, 78.75, 84.94, 88.04, 89.37, 92.07, 91.77, 92.31, 91.07, 90.65, 87.61, 83.41, 78.8, 63.24, 54.89, 47.42, 40.03, 40.26, 30.18, 41.24, 38.09, 36.95, 39.02, 37.83, 36.36, 36.19, 34.8, 36.01, 35.89, 38.28, 40.63, 35.0, 43.8, 39.75, 41.2, 46.04, 45.19, 52.52, 50.11, 47.93, 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null
null
null
Component of an E-cadherin/ catenin adhesion complex composed of at least E-cadherin/CDH1, beta-catenin/CTNNB1 or gamma-catenin/JUP, and potentially alpha-catenin/CTNNA1. Forms a ternary complex composed of ADAM10, CADH1 and EPHA4,
null
null
KLRG1, SPEF1, DLGAP5, AJAP1, RAPGEF2, RAB8B, PIP5K1C, PKP2, TRPV4, CTNNB1, CAV1, DDR1, TBC1D2, CTNNA1, JUP, CTNND1, PSEN1, LIMA1, CDH1, JUP, ADAM10, CADH1 , EPHA4,
null
null
null
null
Homodimer
null
79.91949
0.474025
null
null
288
P12830
Q15784
null
degron_data
CDH1
MGPWSRSLSALLLLLQVSSWLCQEPEPCHPGFDAESYTFTVPRRHLERGRVLGRVNFEDCTGRQRTAYFSLDTRFKVGTDGVITVKRPLRFHNPQIHFLVYAWDSTYRKFSTKVTLNTVGHHHRPPPHQASVSGIQAELLTFPNSSPGLRRQKRDWVIPPISCPENEKGPFPKNLVQIKSNKDKEGKVFYSITGQGADTPPVGVFIIERETGWLKVTEPLDRERIATYTLFSHAVSSNGNAVEDPMEILITVTDQNDNKPEFTQEVFKGSVMEGALPGTSVMEVTATDADDDVNTYNAAIAYTILSQDPELPDKNMFTINRNTGVISVVTTGLDRESFPTYTLVVQAADLQGEGLSTTATAVITVTDTNDNPPIFNPTTYKGQVPENEANVVITTLKVTDADAPNTPAWEAVYTILNDDGGQFVVTTNPVNNDGILKTAKGLDFEAKQQYILHVAVTNVVPFEVSLTTSTATVTVDVLDVNEAPIFVPPEKRVEVSEDFGVGQEITSYTAQEPDTFMEQKITYRIWRDTANWLEINPDTGAISTRAELDREDFEHVKNSTYTALIIATDNGSPVATGTGTLLLILSDVNDNAPIPEPRTIFFCERNPKPQVINIIDADLPPNTSPFTAELTHGASANWTIQYNDPTQESIILKPKMALEVGDYKINLKLMDNQNKDQVTTLEVSVCDCEGAAGVCRKAQPVEAGLQIPAILGILGGILALLILILLLLLFLRRRAVVKEPLLPPEDDTRDNVYYYDEEGGGEEDQDFDLSQLHRGLDARPEVTRNDVAPTLMSVPRYLPRPANPDEIGNFIDENLKAADTDPTAPPYDSLLVFDYEGSGSEAASLSSLNSSESDKDQDYDYLNEWGNRFKKLADMYGGGEDD
Homo sapiens
Cell junction, adherens junction, Cell membrane, Endosome, Golgi apparatus, trans-Golgi network, Cytoplasm, Cell junction, desmosome
Tissue enhanced (parathyroid)
{'Ciliated cells': '119.1', 'Basal respiratory cells': '71.1', 'Club cells': '97.3', 'Ionocytes': '81.0', 'Mucus glandular cells': '155.0', 'Serous glandular cells': '67.8', 'Gastric mucus-secreting cells': '133.2', 'Proximal enterocytes': '140.9', 'Paneth cells': '125.1', 'Distal enterocytes': '307.5', 'Intestinal goblet cells': '173.5', 'Exocrine glandular cells': '-0.605', 'Basal prostatic cells': '68.3', 'Prostatic glandular cells': '186.7', 'Breast glandular cells': '0.773', 'Breast myoepithelial cells': '0.700', 'Glandular and luminal cells': '313.0', 'Secretory cells': '82.3', 'Basal keratinocytes': '102.5', 'Suprabasal keratinocytes': '162.6', 'Basal squamous epithelial cells': '51.0', 'Squamous epithelial cells': '106.9', 'Alveolar cells type 1': '0.437', 'Alveolar cells type 2': '0.706', 'Salivary duct cells': '95.9', 'Ductal cells': '0.541', 'Hepatocytes': '0.600', 'Cholangiocytes': '129.7', 'Proximal tubular cells': '0.042', 'Distal tubular cells': '0.0', 'Collecting duct cells': '143.9', 'Mesothelial cells': '0.799', 'Sertoli cells': '0.252', 'Granulosa cells': '12.9', 'Enteroendocrine cells': '92.4', 'Pancreatic endocrine cells': '78.1', 'Leydig cells': '0.264', 'Excitatory neurons': '0.7', 'Inhibitory neurons': '1.3', 'Cone photoreceptor cells': '0.0', 'Rod photoreceptor cells': '0.0', 'Bipolar cells': '0.2', 'Horizontal cells': '0.6', 'Astrocytes': '0.6', 'Oligodendrocyte precursor cells': '0.5', 'Oligodendrocytes': '29.9', 'Microglial cells': '0.9', 'Muller glia cells': '0.1', 'Schwann cells': '0.131', 'Spermatogonia': '0.392', 'Spermatocytes': '0.193', 'Early spermatids': '-0.217', 'Late spermatids': '-0.290', 'Oocytes': '16.9', 'Cytotrophoblasts': '119.2', 'Syncytiotrophoblasts': '45.0', 'Extravillous trophoblasts': '24.9', 'Endothelial cells': '6.1', 'Lymphatic endothelial cells': '0.4', 'Cardiomyocytes': '0.135', 'Skeletal myocytes': '0.107', 'Smooth muscle cells': '5.8', 'Adipocytes': '2.1', 'Melanocytes': '0.335', 'Fibroblasts': '6.5', 'Peritubular cells': '0.210', 'Endometrial stromal cells': '27.7', 'Ovarian stromal cells': '0.7', 'Undifferentiated cells': '101.6', 'T-cells': '2.9', 'B-cells': '4.4', 'Plasma cells': '6.1', 'Nk-cells': '0.0', 'Granulocytes': '8.4', 'Monocytes': '0.0', 'Macrophages': '6.0', 'Hofbauer cells': '4.3', 'Kupffer cells': '1.0', 'Dendritic cells': '5.9', 'Langerhans cells': '0.304', 'Erythroid cells': '0.036', 'Adipocytes (Subcutaneous)': '-0.081', 'Adipocytes (Visceral)': '-0.209', 'Breast glandular cells (progenitors)': '0.538', 'Adipocytes (Breast)': '-0.689', 'Colon enterocytes': '0.790', 'Colon enteroendocrine cells': '0.112', 'Enteric glia cells': '-0.048', 'Mitotic cells (Colon)': '0.299', 'Mitotic cells (Heart)': '0.120', 'Podocytes': '-0.118', 'Ascending Loop of Henle cells': '0.475', 'Intercalated cells': '0.212', 'Cholangiocyte': '0.090', 'NK-cells (Liver)': '-0.005', 'Respiratory ciliated cells': '-0.012', 'Mitotic cells (Lung)': '0.071', 'NK-cells (Lung)': '-0.266', 'B-cells (Lung)': '-0.296', 'Alpha cells': '0.270', 'Beta cells': '0.152', 'Prostate glandular cells': '0.764', 'Prostate basal glandular cells': '0.540', 'Urothelial cells': '0.205', 'Keratinocyte (other)': '0.510', 'Keratinocyte (granular)': '0.055', 'Hair cortex cells': '0.080', 'Inner root sheath cells': '0.131', 'Outer root sheath cells': '0.175', 'Sebaceous gland cells': '0.156', 'Eccrine sweat gland cells': '-0.207', 'Adipocytes (Skin)': '-0.244', 'Mitotic cells (Skin)': '0.442', 'Parietal cells': '0.654', 'Chief cells': '0.649', 'Gastric mucous cells': '0.781', 'Gastric enteroendocrine cells': '0.590', 'Mitotic cells (Stomach)': '0.445', 'Parafollicular cells': '0.173', 'Thyroid glandular cells': '0.865', 'Mitotic cells (Thyroid)': '-0.081', 'Adrenal cortex cells': '0.051', 'Adrenal medulla cells': '0.087', 'Mitotic cells (Adrenal gland)': '0.072', 'Minor salivary glandular cells': '0.371', 'Minor salivary gland ductal cells': '-0.142', 'Minor salivary gland basal cells': '0.582', 'Mitotic cells (Minor salivary gland)': '0.567', 'Adipocytes (Minor salivary gland)': '0.050', 'Somatotropes': '0.121', 'Lactotropes': '0.322', 'Gonadotropes': '0.330', 'Corticotropes': '0.180', 'Thyrotropes': '0.496', 'Undifferentiated cells (Pituitary gland)': '-0.108', 'Mitotic cells (Spleen)': '-0.228', 'Platelets': '-0.050', 'Erythrocytes': '-0.158', 'Hematopoietic stem cells': '-0.211', 'B-cells (Spleen)': '0.266', 'NK-cells (Spleen)': '0.309', 'Amygdala excitatory': '1.0', 'Cerebellar inhibitory': '0.9', 'Cge interneuron': '0.7', 'Deep-layer corticothalamic and 6b': '1.5', 'Deep-layer intratelencephalic': '0.7', 'Deep-layer near-projecting': '0.7', 'Eccentric medium spiny neuron': '0.6', 'Hippocampal ca1-3': '1.9', 'Hippocampal ca4': '1.2', 'Hippocampal dentate gyrus': '1.1', 'Lamp5-lhx6 and chandelier': '0.5', 'Lower rhombic lip': '0.8', 'Mammillary body': '0.6', 'Medium spiny neuron': '0.7', 'Mge interneuron': '1.7', 'Midbrain-derived inhibitory': '0.7', 'Miscellaneous': '0.9', 'Splatter': '3.8', 'Thalamic excitatory': '0.5', 'Upper rhombic lip': '0.8', 'Upper-layer intratelencephalic': '0.6', 'Astrocyte': '4.4', 'Bergmann glia': '0.2', 'Central nervous system macrophage': '0.6', 'Choroid plexus epithelial cell': '52.1', 'Committed oligodendrocyte precursor': '41.5', 'Ependymal cell': '4.8', 'Oligodendrocyte': '53.1', 'Oligodendrocyte precursor cell': '2.4', 'Endothelial cell': '0.7', 'Pericyte': '0.3', 'Vascular associated smooth muscle cell': '0.0', 'Fibroblast': '17.4', 'Leukocyte': '1.1', 'Basophil': '0.0', 'Eosinophil': '0.0', 'Neutrophil': '0.0', 'Classical monocyte': '0.0', 'Non-classical monocyte': '0.0', 'Intermediate monocyte': '0.0', 'T-reg': '2.3', 'GdT-cell': '0.0', 'MAIT T-cell': '0.0', 'Memory CD4 T-cell': '0.0', 'Naive CD4 T-cell': '0.1', 'Memory CD8 T-cell': '0.2', 'Naive CD8 T-cell': '0.3', 'Memory B-cell': '0.0', 'Naive B-cell': '0.1', 'Plasmacytoid DC': '46.6', 'Myeloid DC': '8.5', 'NK-cell': '0.1', 'Total PBMC': '0.7', 'Vd2 gdTCR': '0.0', 'Memory CD4 T-cell Th1\\/Th17': '0.1', 'Memory CD4 T-cell Th17': '0.2', 'Memory CD4 T-cell Th2': '2.9', 'Non-Vd2 gdTCR': '0.1', 'Memory CD4 T-cell Th1': '0.3', 'Memory CD4 T-cell TFH': '0.5', 'Terminal effector memory CD4 T-cell': '0.0', 'Central memory CD8 T-cell': '4.8', 'Effector memory CD8 T-cell': '0.0', 'Terminal effector memory CD8 T-cell': '0.6', 'Non-switched memory B-cell': '0.0', 'Plasmablast': '3.3', 'Switched memory B-cell': '0.0', 'Exhausted memory B-cell': '0.7', 'Progenitor cell': '2.3', 'Memory T-reg': '1.3', 'Naive CD4 T-cell activated': '0.3', 'Naive CD8 T-cell activated': '0.6', 'Naive T-reg': '0.1'}
1O6S, 2O72, 2OMT, 2OMU, 2OMV, 2OMX, 2OMY, 2OMZ, 3FF7, 3FF8, 3L6X, 3L6Y, 4ZT1, 4ZTE, 6CXY, 6OLE, 6OLF, 6OLG, 6VEL, 7STZ, 8H62
{'Adipose Tissue': 1.2125261088039867, 'Adrenal Gland': 0.1914223992248062, 'Bladder': 39.2033519047619, 'Blood': 1.340954264800861, 'Blood Vessel': 0.3121561692883895, 'Brain': 0.8550442199091597, 'Breast': 38.54918344226579, 'Cervix Uteri': 23.539115789473684, 'Colon': 43.41292142490372, 'Esophagus': 53.97513367404844, 'Fallopian Tube': 14.900277777777776, 'Heart': 0.119140469221835, 'Kidney': 25.040449438202245, 'Liver': 26.60802654867257, 'Lung': 35.447986366782004, 'Muscle': 0.1378936151930261, 'Nerve': 17.518468982229404, 'Ovary': 3.6515122222222223, 'Pancreas': 56.89676829268293, 'Pituitary': 24.68741660777385, 'Prostate': 61.279967346938776, 'Salivary Gland': 92.01685185185184, 'Skin': 79.77571720232172, 'Small Intestine': 71.7519320855615, 'Spleen': 10.061029045643156, 'Stomach': 58.07813805013927, 'Testis': 0.8144204986149585, 'Thyroid': 135.176797856049, 'Uterus': 1.442593943661972, 'Vagina': 86.52345512820513}
NEUROD2
MLTRLFSEPGLLSDVPKFASWGDGEDDEPRSDKGDAPPPPPPAPGPGAPGPARAAKPVPLRGEEGTEATLAEVKEEGELGGEEEEEEEEEEGLDEAEGERPKKRGPKKRKMTKARLERSKLRRQKANARERNRMHDLNAALDNLRKVVPCYSKTQKLSKIETLRLAKNYIWALSEILRSGKRPDLVSYVQTLCKGLSQPTTNLVAGCLQLNSRNFLTEQGADGAGRFHGSGGPFAMHPYPYPCSRLAGAQCQAAGGLGGGAAHALRTHGYCAAYETLYAAAGGGGASPDYNSSEYEGPLSPPLCLNGNFSLKQDSSPDHEKSYHYSMHYSALPGSRPTGHGLVFGSSAVRGGVHSENLLSYDMHLHHDRGPMYEELNAFFHN
Homo sapiens
Nucleus
Tissue enriched (brain)
{'Ciliated cells': '0.0', 'Basal respiratory cells': '0.1', 'Club cells': '0.1', 'Ionocytes': '0.0', 'Mucus glandular cells': '5.0', 'Serous glandular cells': '1.1', 'Gastric mucus-secreting cells': '0.0', 'Proximal enterocytes': '0.0', 'Paneth cells': '0.0', 'Distal enterocytes': '0.1', 'Intestinal goblet cells': '0.0', 'Exocrine glandular cells': '-0.007', 'Basal prostatic cells': '0.1', 'Prostatic glandular cells': '0.7', 'Breast glandular cells': '0.263', 'Breast myoepithelial cells': '0.359', 'Glandular and luminal cells': '0.2', 'Secretory cells': '0.0', 'Basal keratinocytes': '0.4', 'Suprabasal keratinocytes': '0.2', 'Basal squamous epithelial cells': '0.2', 'Squamous epithelial cells': '0.0', 'Alveolar cells type 1': '-0.025', 'Alveolar cells type 2': '-0.048', 'Salivary duct cells': '1.1', 'Ductal cells': '0.043', 'Hepatocytes': '0.008', 'Cholangiocytes': '0.0', 'Proximal tubular cells': '-0.001', 'Distal tubular cells': '0.0', 'Collecting duct cells': '0.0', 'Mesothelial cells': '0.027', 'Sertoli cells': '0.230', 'Granulosa cells': '0.0', 'Enteroendocrine cells': '5.0', 'Pancreatic endocrine cells': '0.0', 'Leydig cells': '0.062', 'Excitatory neurons': '14.4', 'Inhibitory neurons': '0.4', 'Cone photoreceptor cells': '0.0', 'Rod photoreceptor cells': '0.9', 'Bipolar cells': '7.7', 'Horizontal cells': '14.5', 'Astrocytes': '0.9', 'Oligodendrocyte precursor cells': '0.5', 'Oligodendrocytes': '0.9', 'Microglial cells': '1.8', 'Muller glia cells': '0.1', 'Schwann cells': '-0.057', 'Spermatogonia': '0.144', 'Spermatocytes': '0.044', 'Early spermatids': '-0.265', 'Late spermatids': '-0.136', 'Oocytes': '0.0', 'Cytotrophoblasts': '0.2', 'Syncytiotrophoblasts': '0.3', 'Extravillous trophoblasts': '0.2', 'Endothelial cells': '0.3', 'Lymphatic endothelial cells': '0.0', 'Cardiomyocytes': '0.153', 'Skeletal myocytes': '0.078', 'Smooth muscle cells': '0.1', 'Adipocytes': '0.1', 'Melanocytes': '0.203', 'Fibroblasts': '0.3', 'Peritubular cells': '0.062', 'Endometrial stromal cells': '0.2', 'Ovarian stromal cells': '0.2', 'Undifferentiated cells': '1.0', 'T-cells': '0.2', 'B-cells': '0.0', 'Plasma cells': '0.2', 'Nk-cells': '0.9', 'Granulocytes': '0.0', 'Monocytes': '0.0', 'Macrophages': '0.2', 'Hofbauer cells': '0.2', 'Kupffer cells': '0.3', 'Dendritic cells': '0.0', 'Langerhans cells': '0.435', 'Erythroid cells': '0.041', 'Adipocytes (Subcutaneous)': '-0.018', 'Adipocytes (Visceral)': '-0.052', 'Breast glandular cells (progenitors)': '0.171', 'Adipocytes (Breast)': '-0.267', 'Colon enterocytes': '-0.036', 'Colon enteroendocrine cells': '0.016', 'Enteric glia cells': '0.023', 'Mitotic cells (Colon)': '-0.018', 'Mitotic cells (Heart)': '0.121', 'Podocytes': '-0.104', 'Ascending Loop of Henle cells': '0.133', 'Intercalated cells': '-0.084', 'Cholangiocyte': '0.035', 'NK-cells (Liver)': '0.047', 'Respiratory ciliated cells': '0.080', 'Mitotic cells (Lung)': '0.018', 'NK-cells (Lung)': '-0.002', 'B-cells (Lung)': '0.068', 'Alpha cells': '-0.011', 'Beta cells': '0.070', 'Prostate glandular cells': '-0.035', 'Prostate basal glandular cells': '0.099', 'Urothelial cells': '0.028', 'Keratinocyte (other)': '0.474', 'Keratinocyte (granular)': '0.205', 'Hair cortex cells': '-0.253', 'Inner root sheath cells': '-0.261', 'Outer root sheath cells': '-0.226', 'Sebaceous gland cells': '-0.049', 'Eccrine sweat gland cells': '-0.378', 'Adipocytes (Skin)': '-0.377', 'Mitotic cells (Skin)': '0.059', 'Parietal cells': '0.382', 'Chief cells': '0.572', 'Gastric mucous cells': '0.270', 'Gastric enteroendocrine cells': '0.620', 'Mitotic cells (Stomach)': '0.038', 'Parafollicular cells': '0.063', 'Thyroid glandular cells': '0.011', 'Mitotic cells (Thyroid)': '-0.006', 'Adrenal cortex cells': '0.088', 'Adrenal medulla cells': '-0.060', 'Mitotic cells (Adrenal gland)': '0.084', 'Minor salivary glandular cells': '0.098', 'Minor salivary gland ductal cells': '0.057', 'Minor salivary gland basal cells': '-0.013', 'Mitotic cells (Minor salivary gland)': '-0.082', 'Adipocytes (Minor salivary gland)': '-0.265', 'Somatotropes': '0.001', 'Lactotropes': '0.026', 'Gonadotropes': '-0.017', 'Corticotropes': '-0.089', 'Thyrotropes': '-0.004', 'Undifferentiated cells (Pituitary gland)': '0.053', 'Mitotic cells (Spleen)': '-0.022', 'Platelets': '-0.033', 'Erythrocytes': '-0.013', 'Hematopoietic stem cells': '-0.043', 'B-cells (Spleen)': '0.105', 'NK-cells (Spleen)': '0.085', 'Amygdala excitatory': '33.4', 'Cerebellar inhibitory': '49.1', 'Cge interneuron': '0.8', 'Deep-layer corticothalamic and 6b': '45.4', 'Deep-layer intratelencephalic': '41.2', 'Deep-layer near-projecting': '31.0', 'Eccentric medium spiny neuron': '0.8', 'Hippocampal ca1-3': '40.4', 'Hippocampal ca4': '57.1', 'Hippocampal dentate gyrus': '41.3', 'Lamp5-lhx6 and chandelier': '0.4', 'Lower rhombic lip': '26.8', 'Mammillary body': '0.1', 'Medium spiny neuron': '0.5', 'Mge interneuron': '0.6', 'Midbrain-derived inhibitory': '0.1', 'Miscellaneous': '29.7', 'Splatter': '2.6', 'Thalamic excitatory': '2.3', 'Upper rhombic lip': '59.8', 'Upper-layer intratelencephalic': '21.2', 'Astrocyte': '0.6', 'Bergmann glia': '3.8', 'Central nervous system macrophage': '0.8', 'Choroid plexus epithelial cell': '0.9', 'Committed oligodendrocyte precursor': '2.3', 'Ependymal cell': '0.5', 'Oligodendrocyte': '0.6', 'Oligodendrocyte precursor cell': '0.5', 'Endothelial cell': '0.8', 'Pericyte': '0.9', 'Vascular associated smooth muscle cell': '3.5', 'Fibroblast': '0.9', 'Leukocyte': '0.5', 'Basophil': '0.2', 'Eosinophil': '0.0', 'Neutrophil': '0.0', 'Classical monocyte': '0.0', 'Non-classical monocyte': '0.0', 'Intermediate monocyte': '0.1', 'T-reg': '0.1', 'GdT-cell': '0.0', 'MAIT T-cell': '0.1', 'Memory CD4 T-cell': '0.0', 'Naive CD4 T-cell': '0.0', 'Memory CD8 T-cell': '0.0', 'Naive CD8 T-cell': '0.0', 'Memory B-cell': '0.0', 'Naive B-cell': '0.0', 'Plasmacytoid DC': '0.0', 'Myeloid DC': '0.0', 'NK-cell': '0.0', 'Total PBMC': '0.0', 'Vd2 gdTCR': '0.0', 'Memory CD4 T-cell Th1\\/Th17': '0.0', 'Memory CD4 T-cell Th17': '0.0', 'Memory CD4 T-cell Th2': '0.0', 'Non-Vd2 gdTCR': '0.0', 'Memory CD4 T-cell Th1': '0.0', 'Memory CD4 T-cell TFH': '0.0', 'Terminal effector memory CD4 T-cell': '0.0', 'Central memory CD8 T-cell': '0.0', 'Effector memory CD8 T-cell': '0.0', 'Terminal effector memory CD8 T-cell': '0.0', 'Non-switched memory B-cell': '0.0', 'Plasmablast': '0.0', 'Switched memory B-cell': '0.1', 'Exhausted memory B-cell': '0.0', 'Progenitor cell': '0.1', 'Memory T-reg': '0.1', 'Naive CD4 T-cell activated': '0.0', 'Naive CD8 T-cell activated': '0.0', 'Naive T-reg': '0.0'}
null
{'Adipose Tissue': 0.0431921818936877, 'Adrenal Gland': 0.1321565426356589, 'Bladder': 0.0242595238095238, 'Blood': 0.0534136307857911, 'Blood Vessel': 0.0594551123595505, 'Brain': 43.098787558667674, 'Breast': 0.0575405403050108, 'Cervix Uteri': 0.0408605263157894, 'Colon': 0.0492825121951219, 'Esophagus': 0.0432540311418685, 'Fallopian Tube': 0.0992133333333333, 'Heart': 0.0364507874564459, 'Kidney': 0.0248296629213483, 'Liver': 0.0284237433628318, 'Lung': 0.0645535328719723, 'Muscle': 0.0473086500622665, 'Nerve': 0.0652154604200323, 'Ovary': 0.1463963888888889, 'Pancreas': 0.027496125, 'Pituitary': 0.176444628975265, 'Prostate': 0.0522608571428571, 'Salivary Gland': 0.045379012345679, 'Skin': 0.5051645163073522, 'Small Intestine': 0.0691519251336898, 'Spleen': 0.0372263112033195, 'Stomach': 0.1648950835654596, 'Testis': 0.1796587257617728, 'Thyroid': 0.0685713277182235, 'Uterus': 0.06344, 'Vagina': 0.0635486538461538}
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[50.0, 50.9, 51.39, 57.49, 57.58, 55.51, 54.41, 48.49, 50.77, 54.46, 49.34, 44.68, 42.66, 48.94, 52.75, 55.97, 50.27, 45.7, 49.08, 41.87, 42.06, 38.92, 44.67, 42.83, 51.62, 47.5, 53.77, 57.31, 48.91, 53.65, 46.59, 55.32, 47.8, 44.92, 52.05, 63.94, 67.54, 67.52, 70.7, 71.26, 71.92, 67.51, 65.98, 65.17, 65.54, 53.85, 53.06, 57.08, 50.32, 48.53, 53.89, 51.41, 51.74, 48.85, 48.42, 53.39, 46.97, 50.62, 49.88, 52.61, 45.31, 45.99, 46.62, 45.52, 39.3, 44.18, 37.63, 43.78, 38.94, 45.49, 40.68, 47.9, 50.78, 44.73, 52.43, 46.16, 42.36, 43.74, 48.47, 37.12, 39.88, 42.9, 46.86, 42.03, 43.61, 38.51, 45.56, 45.13, 38.74, 44.6, 37.39, 38.13, 38.2, 46.28, 40.45, 48.62, 40.48, 47.53, 47.51, 61.15, 56.65, 54.7, 57.64, 56.1, 69.73, 70.68, 64.62, 71.26, 73.99, 80.77, 83.07, 91.63, 92.96, 93.36, 93.84, 94.86, 96.29, 95.87, 95.7, 97.12, 97.48, 98.0, 98.09, 98.04, 98.25, 98.25, 98.65, 98.5, 98.6, 98.67, 98.71, 98.51, 98.76, 98.66, 98.46, 98.3, 98.46, 98.19, 97.98, 98.4, 98.26, 96.42, 96.81, 98.16, 96.29, 94.59, 95.02, 94.09, 90.38, 84.25, 87.25, 85.81, 83.79, 87.51, 88.62, 92.62, 94.56, 96.0, 97.69, 97.98, 97.27, 97.43, 98.33, 98.04, 97.25, 98.37, 98.29, 97.89, 97.83, 98.18, 97.67, 96.28, 96.54, 97.25, 95.71, 95.88, 96.59, 96.14, 93.79, 92.9, 90.31, 88.0, 87.63, 90.63, 90.63, 90.58, 91.59, 94.03, 93.68, 93.57, 95.11, 96.09, 96.1, 96.14, 96.48, 96.52, 95.97, 94.82, 93.03, 93.89, 94.03, 91.51, 90.43, 91.44, 87.09, 85.73, 83.75, 82.02, 69.96, 61.81, 50.12, 53.01, 50.71, 51.2, 50.86, 55.97, 50.7, 56.5, 56.15, 44.22, 44.84, 46.0, 41.96, 40.84, 38.07, 39.34, 39.72, 42.51, 39.72, 42.89, 43.64, 44.48, 49.63, 43.2, 47.87, 50.87, 49.19, 60.71, 46.57, 53.52, 50.91, 63.15, 39.53, 53.8, 45.15, 52.92, 41.68, 43.38, 49.69, 41.18, 40.01, 38.85, 42.88, 41.61, 39.35, 39.08, 42.58, 37.58, 37.06, 39.64, 39.52, 43.41, 40.12, 43.06, 48.96, 37.86, 48.75, 41.09, 38.82, 40.27, 35.0, 41.85, 43.57, 43.1, 40.62, 47.77, 47.91, 44.81, 48.67, 48.2, 44.87, 36.57, 37.17, 37.54, 36.91, 40.6, 42.8, 57.46, 43.58, 42.44, 42.35, 41.37, 47.93, 39.05, 40.36, 42.78, 51.46, 54.16, 51.75, 52.02, 56.56, 57.85, 61.18, 49.15, 54.02, 39.69, 47.67, 44.16, 51.73, 43.3, 54.26, 54.21, 41.74, 46.17, 39.38, 41.66, 46.25, 44.4, 42.61, 44.05, 51.85, 47.89, 43.8, 51.85, 50.74, 63.69, 55.4, 54.57, 55.59, 48.66, 47.09, 50.1, 55.74, 48.43, 52.27, 45.18, 49.1, 44.02, 46.26, 48.91, 38.85, 47.11, 50.1, 44.01, 42.53, 44.04, 45.31, 42.29, 50.84, 43.98, 33.58, 36.02, 42.98, 37.77, 42.46, 37.52, 40.6, 40.75, 38.12, 36.17, 36.79, 39.94, 42.85, 47.46, 45.44, 46.58, 47.71, 37.61, 44.81, 43.03, 47.82, 53.98, 46.17, 50.37, 54.69, 55.35, 48.47, 54.09, 52.04, 56.93, 54.04, 50.99]
[0.74, 0.57, 0.77, 0.84, 0.85, 0.89, 0.74, 0.78, 0.93, 0.79, 0.85, 0.89, 0.87, 0.94, 0.82, 0.72, 0.93, 0.84, 0.72, 0.81, 0.94, 0.72, 0.82, 0.91, 0.84, 0.96, 0.94, 0.93, 0.95, 0.93, 0.93, 0.92, 1.0, 0.94, 0.99, 0.97, 0.96, 0.95, 0.96, 0.94, 0.96, 0.96, 0.92, 0.96, 0.86, 0.98, 0.91, 0.99, 1.0, 0.98, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 0.99, 0.93, 1.0, 0.9, 1.0, 1.0, 0.99, 1.0, 0.98, 0.92, 0.89, 0.81, 0.87, 0.8, 0.81, 0.82, 0.67, 0.73, 0.89, 0.92, 0.78, 0.92, 0.98, 1.0, 1.0, 0.9, 0.92, 0.84, 0.91, 0.98, 1.0, 0.94, 0.87, 0.88, 0.89, 0.93, 0.88, 1.0, 0.77, 0.99, 0.92, 0.91, 0.91, 0.91, 0.95, 0.67, 0.92, 0.84, 0.9, 0.86, 0.93, 0.49, 0.64, 0.72, 0.68, 0.63, 0.57, 0.49, 0.66, 0.46, 0.52, 0.64, 0.68, 0.71, 0.52, 0.66, 0.35, 0.54, 0.39, 0.57, 0.46, 0.64, 0.59, 0.63, 0.42, 0.58, 0.67, 0.58, 0.33, 0.44, 0.5, 0.14, 0.28, 0.49, 0.29, 0.12, 0.57, 0.66, 0.07, 0.19, 0.14, 0.48, 0.23, 0.82, 0.93, 0.56, 0.62, 0.13, 0.41, 0.52, 0.56, 0.18, 0.01, 0.56, 0.47, 0.0, 0.11, 0.73, 0.13, 0.27, 0.64, 0.56, 0.06, 0.37, 0.41, 0.33, 0.27, 0.8, 0.67, 0.5, 0.78, 0.73, 0.82, 0.47, 0.6, 0.5, 0.39, 0.47, 0.2, 0.0, 0.43, 0.18, 0.0, 0.02, 0.71, 0.57, 0.14, 0.34, 0.54, 0.66, 0.04, 0.03, 0.52, 0.2, 0.01, 0.18, 0.63, 0.44, 0.29, 0.69, 0.19, 0.7, 0.68, 0.93, 0.65, 0.14, 0.71, 0.8, 0.69, 0.52, 0.91, 0.68, 0.98, 0.93, 0.95, 1.0, 1.0, 1.0, 1.0, 0.99, 1.0, 0.98, 0.96, 1.0, 0.99, 0.97, 1.0, 0.96, 1.0, 0.95, 0.94, 0.97, 0.87, 0.95, 0.88, 0.96, 0.96, 0.99, 1.0, 1.0, 1.0, 0.98, 1.0, 0.99, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 0.99, 1.0, 0.97, 0.95, 0.95, 0.9, 0.96, 0.93, 0.91, 0.9, 0.94, 0.82, 0.97, 0.75, 1.0, 0.89, 0.84, 0.97, 0.95, 0.8, 0.84, 0.93, 0.99, 1.0, 1.0, 0.93, 0.96, 0.94, 0.83, 0.94, 0.87, 0.86, 0.82, 0.85, 0.95, 0.94, 0.95, 0.7, 0.95, 0.95, 0.96, 0.91, 0.83, 0.91, 0.83, 0.91, 0.93, 0.85, 0.94, 0.94, 1.0, 0.96, 0.99, 0.97, 0.97, 0.97, 0.98, 1.0, 0.99, 0.9, 1.0, 0.83, 0.95, 0.93, 0.87, 0.86, 0.56, 0.7, 0.8, 0.86, 0.9, 0.89, 0.96, 0.94, 0.93, 0.98, 0.99, 0.99, 0.99, 0.97, 0.99, 0.98, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 0.97, 1.0, 0.94, 1.0, 0.88, 1.0, 0.95, 0.99, 0.94, 1.0, 0.93, 0.91, 0.96, 0.91, 0.93, 0.92, 0.86, 0.94, 0.59, 0.77, 0.94, 0.89, 0.86, 0.93, 0.85, 0.95, 0.85, 0.96, 0.95, 0.98, 1.0]
null
Component of an E-cadherin/ catenin adhesion complex composed of at least E-cadherin/CDH1, beta-catenin/CTNNB1 or gamma-catenin/JUP, and potentially alpha-catenin/CTNNA1. Forms a ternary complex composed of ADAM10, CADH1 and EPHA4,
null
null
KLRG1, SPEF1, DLGAP5, AJAP1, RAPGEF2, RAB8B, PIP5K1C, PKP2, TRPV4, CTNNB1, CAV1, DDR1, TBC1D2, CTNNA1, JUP, CTNND1, PSEN1, LIMA1, CDH1, JUP, ADAM10, CADH1 , EPHA4,
null
null
null
null
Homodimer
null
79.91949
0.474025
59.993743
0.789136
2,038
P12830
Q16875
null
degron_data
CDH1
MGPWSRSLSALLLLLQVSSWLCQEPEPCHPGFDAESYTFTVPRRHLERGRVLGRVNFEDCTGRQRTAYFSLDTRFKVGTDGVITVKRPLRFHNPQIHFLVYAWDSTYRKFSTKVTLNTVGHHHRPPPHQASVSGIQAELLTFPNSSPGLRRQKRDWVIPPISCPENEKGPFPKNLVQIKSNKDKEGKVFYSITGQGADTPPVGVFIIERETGWLKVTEPLDRERIATYTLFSHAVSSNGNAVEDPMEILITVTDQNDNKPEFTQEVFKGSVMEGALPGTSVMEVTATDADDDVNTYNAAIAYTILSQDPELPDKNMFTINRNTGVISVVTTGLDRESFPTYTLVVQAADLQGEGLSTTATAVITVTDTNDNPPIFNPTTYKGQVPENEANVVITTLKVTDADAPNTPAWEAVYTILNDDGGQFVVTTNPVNNDGILKTAKGLDFEAKQQYILHVAVTNVVPFEVSLTTSTATVTVDVLDVNEAPIFVPPEKRVEVSEDFGVGQEITSYTAQEPDTFMEQKITYRIWRDTANWLEINPDTGAISTRAELDREDFEHVKNSTYTALIIATDNGSPVATGTGTLLLILSDVNDNAPIPEPRTIFFCERNPKPQVINIIDADLPPNTSPFTAELTHGASANWTIQYNDPTQESIILKPKMALEVGDYKINLKLMDNQNKDQVTTLEVSVCDCEGAAGVCRKAQPVEAGLQIPAILGILGGILALLILILLLLLFLRRRAVVKEPLLPPEDDTRDNVYYYDEEGGGEEDQDFDLSQLHRGLDARPEVTRNDVAPTLMSVPRYLPRPANPDEIGNFIDENLKAADTDPTAPPYDSLLVFDYEGSGSEAASLSSLNSSESDKDQDYDYLNEWGNRFKKLADMYGGGEDD
Homo sapiens
Cell junction, adherens junction, Cell membrane, Endosome, Golgi apparatus, trans-Golgi network, Cytoplasm, Cell junction, desmosome
Tissue enhanced (parathyroid)
{'Ciliated cells': '119.1', 'Basal respiratory cells': '71.1', 'Club cells': '97.3', 'Ionocytes': '81.0', 'Mucus glandular cells': '155.0', 'Serous glandular cells': '67.8', 'Gastric mucus-secreting cells': '133.2', 'Proximal enterocytes': '140.9', 'Paneth cells': '125.1', 'Distal enterocytes': '307.5', 'Intestinal goblet cells': '173.5', 'Exocrine glandular cells': '-0.605', 'Basal prostatic cells': '68.3', 'Prostatic glandular cells': '186.7', 'Breast glandular cells': '0.773', 'Breast myoepithelial cells': '0.700', 'Glandular and luminal cells': '313.0', 'Secretory cells': '82.3', 'Basal keratinocytes': '102.5', 'Suprabasal keratinocytes': '162.6', 'Basal squamous epithelial cells': '51.0', 'Squamous epithelial cells': '106.9', 'Alveolar cells type 1': '0.437', 'Alveolar cells type 2': '0.706', 'Salivary duct cells': '95.9', 'Ductal cells': '0.541', 'Hepatocytes': '0.600', 'Cholangiocytes': '129.7', 'Proximal tubular cells': '0.042', 'Distal tubular cells': '0.0', 'Collecting duct cells': '143.9', 'Mesothelial cells': '0.799', 'Sertoli cells': '0.252', 'Granulosa cells': '12.9', 'Enteroendocrine cells': '92.4', 'Pancreatic endocrine cells': '78.1', 'Leydig cells': '0.264', 'Excitatory neurons': '0.7', 'Inhibitory neurons': '1.3', 'Cone photoreceptor cells': '0.0', 'Rod photoreceptor cells': '0.0', 'Bipolar cells': '0.2', 'Horizontal cells': '0.6', 'Astrocytes': '0.6', 'Oligodendrocyte precursor cells': '0.5', 'Oligodendrocytes': '29.9', 'Microglial cells': '0.9', 'Muller glia cells': '0.1', 'Schwann cells': '0.131', 'Spermatogonia': '0.392', 'Spermatocytes': '0.193', 'Early spermatids': '-0.217', 'Late spermatids': '-0.290', 'Oocytes': '16.9', 'Cytotrophoblasts': '119.2', 'Syncytiotrophoblasts': '45.0', 'Extravillous trophoblasts': '24.9', 'Endothelial cells': '6.1', 'Lymphatic endothelial cells': '0.4', 'Cardiomyocytes': '0.135', 'Skeletal myocytes': '0.107', 'Smooth muscle cells': '5.8', 'Adipocytes': '2.1', 'Melanocytes': '0.335', 'Fibroblasts': '6.5', 'Peritubular cells': '0.210', 'Endometrial stromal cells': '27.7', 'Ovarian stromal cells': '0.7', 'Undifferentiated cells': '101.6', 'T-cells': '2.9', 'B-cells': '4.4', 'Plasma cells': '6.1', 'Nk-cells': '0.0', 'Granulocytes': '8.4', 'Monocytes': '0.0', 'Macrophages': '6.0', 'Hofbauer cells': '4.3', 'Kupffer cells': '1.0', 'Dendritic cells': '5.9', 'Langerhans cells': '0.304', 'Erythroid cells': '0.036', 'Adipocytes (Subcutaneous)': '-0.081', 'Adipocytes (Visceral)': '-0.209', 'Breast glandular cells (progenitors)': '0.538', 'Adipocytes (Breast)': '-0.689', 'Colon enterocytes': '0.790', 'Colon enteroendocrine cells': '0.112', 'Enteric glia cells': '-0.048', 'Mitotic cells (Colon)': '0.299', 'Mitotic cells (Heart)': '0.120', 'Podocytes': '-0.118', 'Ascending Loop of Henle cells': '0.475', 'Intercalated cells': '0.212', 'Cholangiocyte': '0.090', 'NK-cells (Liver)': '-0.005', 'Respiratory ciliated cells': '-0.012', 'Mitotic cells (Lung)': '0.071', 'NK-cells (Lung)': '-0.266', 'B-cells (Lung)': '-0.296', 'Alpha cells': '0.270', 'Beta cells': '0.152', 'Prostate glandular cells': '0.764', 'Prostate basal glandular cells': '0.540', 'Urothelial cells': '0.205', 'Keratinocyte (other)': '0.510', 'Keratinocyte (granular)': '0.055', 'Hair cortex cells': '0.080', 'Inner root sheath cells': '0.131', 'Outer root sheath cells': '0.175', 'Sebaceous gland cells': '0.156', 'Eccrine sweat gland cells': '-0.207', 'Adipocytes (Skin)': '-0.244', 'Mitotic cells (Skin)': '0.442', 'Parietal cells': '0.654', 'Chief cells': '0.649', 'Gastric mucous cells': '0.781', 'Gastric enteroendocrine cells': '0.590', 'Mitotic cells (Stomach)': '0.445', 'Parafollicular cells': '0.173', 'Thyroid glandular cells': '0.865', 'Mitotic cells (Thyroid)': '-0.081', 'Adrenal cortex cells': '0.051', 'Adrenal medulla cells': '0.087', 'Mitotic cells (Adrenal gland)': '0.072', 'Minor salivary glandular cells': '0.371', 'Minor salivary gland ductal cells': '-0.142', 'Minor salivary gland basal cells': '0.582', 'Mitotic cells (Minor salivary gland)': '0.567', 'Adipocytes (Minor salivary gland)': '0.050', 'Somatotropes': '0.121', 'Lactotropes': '0.322', 'Gonadotropes': '0.330', 'Corticotropes': '0.180', 'Thyrotropes': '0.496', 'Undifferentiated cells (Pituitary gland)': '-0.108', 'Mitotic cells (Spleen)': '-0.228', 'Platelets': '-0.050', 'Erythrocytes': '-0.158', 'Hematopoietic stem cells': '-0.211', 'B-cells (Spleen)': '0.266', 'NK-cells (Spleen)': '0.309', 'Amygdala excitatory': '1.0', 'Cerebellar inhibitory': '0.9', 'Cge interneuron': '0.7', 'Deep-layer corticothalamic and 6b': '1.5', 'Deep-layer intratelencephalic': '0.7', 'Deep-layer near-projecting': '0.7', 'Eccentric medium spiny neuron': '0.6', 'Hippocampal ca1-3': '1.9', 'Hippocampal ca4': '1.2', 'Hippocampal dentate gyrus': '1.1', 'Lamp5-lhx6 and chandelier': '0.5', 'Lower rhombic lip': '0.8', 'Mammillary body': '0.6', 'Medium spiny neuron': '0.7', 'Mge interneuron': '1.7', 'Midbrain-derived inhibitory': '0.7', 'Miscellaneous': '0.9', 'Splatter': '3.8', 'Thalamic excitatory': '0.5', 'Upper rhombic lip': '0.8', 'Upper-layer intratelencephalic': '0.6', 'Astrocyte': '4.4', 'Bergmann glia': '0.2', 'Central nervous system macrophage': '0.6', 'Choroid plexus epithelial cell': '52.1', 'Committed oligodendrocyte precursor': '41.5', 'Ependymal cell': '4.8', 'Oligodendrocyte': '53.1', 'Oligodendrocyte precursor cell': '2.4', 'Endothelial cell': '0.7', 'Pericyte': '0.3', 'Vascular associated smooth muscle cell': '0.0', 'Fibroblast': '17.4', 'Leukocyte': '1.1', 'Basophil': '0.0', 'Eosinophil': '0.0', 'Neutrophil': '0.0', 'Classical monocyte': '0.0', 'Non-classical monocyte': '0.0', 'Intermediate monocyte': '0.0', 'T-reg': '2.3', 'GdT-cell': '0.0', 'MAIT T-cell': '0.0', 'Memory CD4 T-cell': '0.0', 'Naive CD4 T-cell': '0.1', 'Memory CD8 T-cell': '0.2', 'Naive CD8 T-cell': '0.3', 'Memory B-cell': '0.0', 'Naive B-cell': '0.1', 'Plasmacytoid DC': '46.6', 'Myeloid DC': '8.5', 'NK-cell': '0.1', 'Total PBMC': '0.7', 'Vd2 gdTCR': '0.0', 'Memory CD4 T-cell Th1\\/Th17': '0.1', 'Memory CD4 T-cell Th17': '0.2', 'Memory CD4 T-cell Th2': '2.9', 'Non-Vd2 gdTCR': '0.1', 'Memory CD4 T-cell Th1': '0.3', 'Memory CD4 T-cell TFH': '0.5', 'Terminal effector memory CD4 T-cell': '0.0', 'Central memory CD8 T-cell': '4.8', 'Effector memory CD8 T-cell': '0.0', 'Terminal effector memory CD8 T-cell': '0.6', 'Non-switched memory B-cell': '0.0', 'Plasmablast': '3.3', 'Switched memory B-cell': '0.0', 'Exhausted memory B-cell': '0.7', 'Progenitor cell': '2.3', 'Memory T-reg': '1.3', 'Naive CD4 T-cell activated': '0.3', 'Naive CD8 T-cell activated': '0.6', 'Naive T-reg': '0.1'}
1O6S, 2O72, 2OMT, 2OMU, 2OMV, 2OMX, 2OMY, 2OMZ, 3FF7, 3FF8, 3L6X, 3L6Y, 4ZT1, 4ZTE, 6CXY, 6OLE, 6OLF, 6OLG, 6VEL, 7STZ, 8H62
{'Adipose Tissue': 1.2125261088039867, 'Adrenal Gland': 0.1914223992248062, 'Bladder': 39.2033519047619, 'Blood': 1.340954264800861, 'Blood Vessel': 0.3121561692883895, 'Brain': 0.8550442199091597, 'Breast': 38.54918344226579, 'Cervix Uteri': 23.539115789473684, 'Colon': 43.41292142490372, 'Esophagus': 53.97513367404844, 'Fallopian Tube': 14.900277777777776, 'Heart': 0.119140469221835, 'Kidney': 25.040449438202245, 'Liver': 26.60802654867257, 'Lung': 35.447986366782004, 'Muscle': 0.1378936151930261, 'Nerve': 17.518468982229404, 'Ovary': 3.6515122222222223, 'Pancreas': 56.89676829268293, 'Pituitary': 24.68741660777385, 'Prostate': 61.279967346938776, 'Salivary Gland': 92.01685185185184, 'Skin': 79.77571720232172, 'Small Intestine': 71.7519320855615, 'Spleen': 10.061029045643156, 'Stomach': 58.07813805013927, 'Testis': 0.8144204986149585, 'Thyroid': 135.176797856049, 'Uterus': 1.442593943661972, 'Vagina': 86.52345512820513}
PFKFB3
MPLELTQSRVQKIWVPVDHRPSLPRSCGPKLTNSPTVIVMVGLPARGKTYISKKLTRYLNWIGVPTKVFNVGEYRREAVKQYSSYNFFRPDNEEAMKVRKQCALAALRDVKSYLAKEGGQIAVFDATNTTRERRHMILHFAKENDFKAFFIESVCDDPTVVASNIMEVKISSPDYKDCNSAEAMDDFMKRISCYEASYQPLDPDKCDRDLSLIKVIDVGRRFLVNRVQDHIQSRIVYYLMNIHVQPRTIYLCRHGENEHNLQGRIGGDSGLSSRGKKFASALSKFVEEQNLKDLRVWTSQLKSTIQTAEALRLPYEQWKALNEIDAGVCEELTYEEIRDTYPEEYALREQDKYYYRYPTGESYQDLVQRLEPVIMELERQENVLVICHQAVLRCLLAYFLDKSAEEMPYLKCPLHTVLKLTPVAYGCRVESIYLNVESVCTHRERSEDAKKGPNPLMRRNSVTPLASPEPTKKPRINSFEEHVASTSAALPSCLPPEVPTQLPGQNMKGSRSSADSSRKH
Homo sapiens
null
Tissue enhanced (adipose tissue, skeletal muscle)
{'Ciliated cells': '28.1', 'Basal respiratory cells': '22.0', 'Club cells': '17.9', 'Ionocytes': '17.3', 'Mucus glandular cells': '23.4', 'Serous glandular cells': '10.3', 'Gastric mucus-secreting cells': '26.5', 'Proximal enterocytes': '6.5', 'Paneth cells': '5.2', 'Distal enterocytes': '5.6', 'Intestinal goblet cells': '6.1', 'Exocrine glandular cells': '-0.635', 'Basal prostatic cells': '63.9', 'Prostatic glandular cells': '3.9', 'Breast glandular cells': '-0.406', 'Breast myoepithelial cells': '-0.418', 'Glandular and luminal cells': '61.8', 'Secretory cells': '20.1', 'Basal keratinocytes': '69.6', 'Suprabasal keratinocytes': '45.0', 'Basal squamous epithelial cells': '28.4', 'Squamous epithelial cells': '18.9', 'Alveolar cells type 1': '0.120', 'Alveolar cells type 2': '-0.309', 'Salivary duct cells': '35.2', 'Ductal cells': '0.505', 'Hepatocytes': '0.088', 'Cholangiocytes': '22.9', 'Proximal tubular cells': '-0.192', 'Distal tubular cells': '0.0', 'Collecting duct cells': '184.8', 'Mesothelial cells': '-0.252', 'Sertoli cells': '0.525', 'Granulosa cells': '16.3', 'Enteroendocrine cells': '14.2', 'Pancreatic endocrine cells': '20.4', 'Leydig cells': '0.545', 'Excitatory neurons': '41.4', 'Inhibitory neurons': '18.6', 'Cone photoreceptor cells': '39.1', 'Rod photoreceptor cells': '3.6', 'Bipolar cells': '7.9', 'Horizontal cells': '10.7', 'Astrocytes': '145.8', 'Oligodendrocyte precursor cells': '13.2', 'Oligodendrocytes': '29.7', 'Microglial cells': '39.4', 'Muller glia cells': '6.1', 'Schwann cells': '-0.047', 'Spermatogonia': '0.299', 'Spermatocytes': '-0.074', 'Early spermatids': '-0.397', 'Late spermatids': '-0.512', 'Oocytes': '8.1', 'Cytotrophoblasts': '0.4', 'Syncytiotrophoblasts': '0.7', 'Extravillous trophoblasts': '7.7', 'Endothelial cells': '24.3', 'Lymphatic endothelial cells': '8.6', 'Cardiomyocytes': '0.234', 'Skeletal myocytes': '-0.148', 'Smooth muscle cells': '19.7', 'Adipocytes': '33.3', 'Melanocytes': '-0.165', 'Fibroblasts': '24.7', 'Peritubular cells': '0.444', 'Endometrial stromal cells': '18.1', 'Ovarian stromal cells': '5.6', 'Undifferentiated cells': '7.0', 'T-cells': '79.7', 'B-cells': '28.3', 'Plasma cells': '20.6', 'Nk-cells': '38.3', 'Granulocytes': '36.4', 'Monocytes': '329.1', 'Macrophages': '138.1', 'Hofbauer cells': '59.8', 'Kupffer cells': '83.9', 'Dendritic cells': '163.5', 'Langerhans cells': '-0.213', 'Erythroid cells': '0.034', 'Adipocytes (Subcutaneous)': '0.764', 'Adipocytes (Visceral)': '0.740', 'Breast glandular cells (progenitors)': '-0.264', 'Adipocytes (Breast)': '0.821', 'Colon enterocytes': '-0.113', 'Colon enteroendocrine cells': '0.250', 'Enteric glia cells': '0.226', 'Mitotic cells (Colon)': '0.019', 'Mitotic cells (Heart)': '0.321', 'Podocytes': '-0.371', 'Ascending Loop of Henle cells': '0.381', 'Intercalated cells': '-0.224', 'Cholangiocyte': '0.338', 'NK-cells (Liver)': '-0.310', 'Respiratory ciliated cells': '-0.008', 'Mitotic cells (Lung)': '-0.169', 'NK-cells (Lung)': '0.380', 'B-cells (Lung)': '0.260', 'Alpha cells': '0.303', 'Beta cells': '0.154', 'Prostate glandular cells': '-0.287', 'Prostate basal glandular cells': '0.122', 'Urothelial cells': '0.262', 'Keratinocyte (other)': '-0.314', 'Keratinocyte (granular)': '-0.339', 'Hair cortex cells': '0.310', 'Inner root sheath cells': '0.282', 'Outer root sheath cells': '0.366', 'Sebaceous gland cells': '-0.123', 'Eccrine sweat gland cells': '0.651', 'Adipocytes (Skin)': '0.303', 'Mitotic cells (Skin)': '0.056', 'Parietal cells': '-0.421', 'Chief cells': '-0.375', 'Gastric mucous cells': '-0.110', 'Gastric enteroendocrine cells': '-0.209', 'Mitotic cells (Stomach)': '0.051', 'Parafollicular cells': '0.002', 'Thyroid glandular cells': '-0.178', 'Mitotic cells (Thyroid)': '0.250', 'Adrenal cortex cells': '0.203', 'Adrenal medulla cells': '-0.126', 'Mitotic cells (Adrenal gland)': '-0.210', 'Minor salivary glandular cells': '0.207', 'Minor salivary gland ductal cells': '0.072', 'Minor salivary gland basal cells': '0.303', 'Mitotic cells (Minor salivary gland)': '0.243', 'Adipocytes (Minor salivary gland)': '0.240', 'Somatotropes': '-0.260', 'Lactotropes': '-0.067', 'Gonadotropes': '0.082', 'Corticotropes': '-0.002', 'Thyrotropes': '0.137', 'Undifferentiated cells (Pituitary gland)': '0.062', 'Mitotic cells (Spleen)': '-0.237', 'Platelets': '-0.120', 'Erythrocytes': '-0.216', 'Hematopoietic stem cells': '-0.062', 'B-cells (Spleen)': '0.091', 'NK-cells (Spleen)': '0.124', 'Amygdala excitatory': '72.2', 'Cerebellar inhibitory': '34.7', 'Cge interneuron': '12.1', 'Deep-layer corticothalamic and 6b': '44.0', 'Deep-layer intratelencephalic': '71.8', 'Deep-layer near-projecting': '49.5', 'Eccentric medium spiny neuron': '35.4', 'Hippocampal ca1-3': '46.5', 'Hippocampal ca4': '39.6', 'Hippocampal dentate gyrus': '62.1', 'Lamp5-lhx6 and chandelier': '28.2', 'Lower rhombic lip': '49.4', 'Mammillary body': '53.8', 'Medium spiny neuron': '32.5', 'Mge interneuron': '40.6', 'Midbrain-derived inhibitory': '7.8', 'Miscellaneous': '49.1', 'Splatter': '31.6', 'Thalamic excitatory': '34.3', 'Upper rhombic lip': '26.6', 'Upper-layer intratelencephalic': '83.2', 'Astrocyte': '401.0', 'Bergmann glia': '213.6', 'Central nervous system macrophage': '240.7', 'Choroid plexus epithelial cell': '15.8', 'Committed oligodendrocyte precursor': '35.9', 'Ependymal cell': '114.2', 'Oligodendrocyte': '46.8', 'Oligodendrocyte precursor cell': '33.4', 'Endothelial cell': '38.8', 'Pericyte': '52.8', 'Vascular associated smooth muscle cell': '38.1', 'Fibroblast': '72.3', 'Leukocyte': '79.2', 'Basophil': '49.2', 'Eosinophil': '7.8', 'Neutrophil': '351.4', 'Classical monocyte': '297.4', 'Non-classical monocyte': '141.6', 'Intermediate monocyte': '284.0', 'T-reg': '25.1', 'GdT-cell': '2.2', 'MAIT T-cell': '36.0', 'Memory CD4 T-cell': '4.2', 'Naive CD4 T-cell': '21.1', 'Memory CD8 T-cell': '2.9', 'Naive CD8 T-cell': '26.8', 'Memory B-cell': '1.8', 'Naive B-cell': '10.6', 'Plasmacytoid DC': '13.0', 'Myeloid DC': '51.9', 'NK-cell': '13.5', 'Total PBMC': '59.5', 'Vd2 gdTCR': '20.8', 'Memory CD4 T-cell Th1\\/Th17': '87.1', 'Memory CD4 T-cell Th17': '79.9', 'Memory CD4 T-cell Th2': '44.2', 'Non-Vd2 gdTCR': '12.3', 'Memory CD4 T-cell Th1': '69.5', 'Memory CD4 T-cell TFH': '64.8', 'Terminal effector memory CD4 T-cell': '14.0', 'Central memory CD8 T-cell': '32.2', 'Effector memory CD8 T-cell': '15.5', 'Terminal effector memory CD8 T-cell': '10.3', 'Non-switched memory B-cell': '19.5', 'Plasmablast': '13.6', 'Switched memory B-cell': '15.2', 'Exhausted memory B-cell': '20.0', 'Progenitor cell': '23.9', 'Memory T-reg': '55.6', 'Naive CD4 T-cell activated': '338.1', 'Naive CD8 T-cell activated': '206.6', 'Naive T-reg': '24.5'}
2AXN, 2DWO, 2DWP, 2I1V, 3QPU, 3QPV, 3QPW, 4D4J, 4D4K, 4D4L, 4D4M, 4MA4, 5AJV, 5AJW, 5AJX, 5AJY, 5AJZ, 5AK0, 6ETJ, 6HVH, 6HVI, 6HVJ, 6IBX, 6IBY, 6IBZ, 6IC0
{'Adipose Tissue': 264.88431063122925, 'Adrenal Gland': 20.997612403100774, 'Bladder': 38.70857142857143, 'Blood': 137.5398934337998, 'Blood Vessel': 95.86592359550562, 'Brain': 44.32595344436033, 'Breast': 191.20278867102397, 'Cervix Uteri': 35.99947368421053, 'Colon': 25.623186136071887, 'Esophagus': 39.86713494809689, 'Fallopian Tube': 51.22222222222222, 'Heart': 11.82161231126597, 'Kidney': 72.43587640449438, 'Liver': 18.221929203539823, 'Lung': 106.3375259515571, 'Muscle': 368.3814084682441, 'Nerve': 59.53513731825525, 'Ovary': 38.660555555555554, 'Pancreas': 9.285990853658536, 'Pituitary': 58.39116607773852, 'Prostate': 30.475420408163263, 'Salivary Gland': 49.12745061728395, 'Skin': 54.77566998341626, 'Small Intestine': 29.635085561497327, 'Spleen': 65.73904564315353, 'Stomach': 26.795484679665737, 'Testis': 24.596440443213297, 'Thyroid': 18.44838897396631, 'Uterus': 26.158169014084507, 'Vagina': 58.73846153846154}
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null
Component of an E-cadherin/ catenin adhesion complex composed of at least E-cadherin/CDH1, beta-catenin/CTNNB1 or gamma-catenin/JUP, and potentially alpha-catenin/CTNNA1. Forms a ternary complex composed of ADAM10, CADH1 and EPHA4,
null
null
KLRG1, SPEF1, DLGAP5, AJAP1, RAPGEF2, RAB8B, PIP5K1C, PKP2, TRPV4, CTNNB1, CAV1, DDR1, TBC1D2, CTNNA1, JUP, CTNND1, PSEN1, LIMA1, CDH1, JUP, ADAM10, CADH1 , EPHA4,
null
null
null
null
Homodimer
null
79.91949
0.474025
86.458327
0.376058
1,509
P12830
Q5FBB7
null
degron_data
CDH1
MGPWSRSLSALLLLLQVSSWLCQEPEPCHPGFDAESYTFTVPRRHLERGRVLGRVNFEDCTGRQRTAYFSLDTRFKVGTDGVITVKRPLRFHNPQIHFLVYAWDSTYRKFSTKVTLNTVGHHHRPPPHQASVSGIQAELLTFPNSSPGLRRQKRDWVIPPISCPENEKGPFPKNLVQIKSNKDKEGKVFYSITGQGADTPPVGVFIIERETGWLKVTEPLDRERIATYTLFSHAVSSNGNAVEDPMEILITVTDQNDNKPEFTQEVFKGSVMEGALPGTSVMEVTATDADDDVNTYNAAIAYTILSQDPELPDKNMFTINRNTGVISVVTTGLDRESFPTYTLVVQAADLQGEGLSTTATAVITVTDTNDNPPIFNPTTYKGQVPENEANVVITTLKVTDADAPNTPAWEAVYTILNDDGGQFVVTTNPVNNDGILKTAKGLDFEAKQQYILHVAVTNVVPFEVSLTTSTATVTVDVLDVNEAPIFVPPEKRVEVSEDFGVGQEITSYTAQEPDTFMEQKITYRIWRDTANWLEINPDTGAISTRAELDREDFEHVKNSTYTALIIATDNGSPVATGTGTLLLILSDVNDNAPIPEPRTIFFCERNPKPQVINIIDADLPPNTSPFTAELTHGASANWTIQYNDPTQESIILKPKMALEVGDYKINLKLMDNQNKDQVTTLEVSVCDCEGAAGVCRKAQPVEAGLQIPAILGILGGILALLILILLLLLFLRRRAVVKEPLLPPEDDTRDNVYYYDEEGGGEEDQDFDLSQLHRGLDARPEVTRNDVAPTLMSVPRYLPRPANPDEIGNFIDENLKAADTDPTAPPYDSLLVFDYEGSGSEAASLSSLNSSESDKDQDYDYLNEWGNRFKKLADMYGGGEDD
Homo sapiens
Cell junction, adherens junction, Cell membrane, Endosome, Golgi apparatus, trans-Golgi network, Cytoplasm, Cell junction, desmosome
Tissue enhanced (parathyroid)
{'Ciliated cells': '119.1', 'Basal respiratory cells': '71.1', 'Club cells': '97.3', 'Ionocytes': '81.0', 'Mucus glandular cells': '155.0', 'Serous glandular cells': '67.8', 'Gastric mucus-secreting cells': '133.2', 'Proximal enterocytes': '140.9', 'Paneth cells': '125.1', 'Distal enterocytes': '307.5', 'Intestinal goblet cells': '173.5', 'Exocrine glandular cells': '-0.605', 'Basal prostatic cells': '68.3', 'Prostatic glandular cells': '186.7', 'Breast glandular cells': '0.773', 'Breast myoepithelial cells': '0.700', 'Glandular and luminal cells': '313.0', 'Secretory cells': '82.3', 'Basal keratinocytes': '102.5', 'Suprabasal keratinocytes': '162.6', 'Basal squamous epithelial cells': '51.0', 'Squamous epithelial cells': '106.9', 'Alveolar cells type 1': '0.437', 'Alveolar cells type 2': '0.706', 'Salivary duct cells': '95.9', 'Ductal cells': '0.541', 'Hepatocytes': '0.600', 'Cholangiocytes': '129.7', 'Proximal tubular cells': '0.042', 'Distal tubular cells': '0.0', 'Collecting duct cells': '143.9', 'Mesothelial cells': '0.799', 'Sertoli cells': '0.252', 'Granulosa cells': '12.9', 'Enteroendocrine cells': '92.4', 'Pancreatic endocrine cells': '78.1', 'Leydig cells': '0.264', 'Excitatory neurons': '0.7', 'Inhibitory neurons': '1.3', 'Cone photoreceptor cells': '0.0', 'Rod photoreceptor cells': '0.0', 'Bipolar cells': '0.2', 'Horizontal cells': '0.6', 'Astrocytes': '0.6', 'Oligodendrocyte precursor cells': '0.5', 'Oligodendrocytes': '29.9', 'Microglial cells': '0.9', 'Muller glia cells': '0.1', 'Schwann cells': '0.131', 'Spermatogonia': '0.392', 'Spermatocytes': '0.193', 'Early spermatids': '-0.217', 'Late spermatids': '-0.290', 'Oocytes': '16.9', 'Cytotrophoblasts': '119.2', 'Syncytiotrophoblasts': '45.0', 'Extravillous trophoblasts': '24.9', 'Endothelial cells': '6.1', 'Lymphatic endothelial cells': '0.4', 'Cardiomyocytes': '0.135', 'Skeletal myocytes': '0.107', 'Smooth muscle cells': '5.8', 'Adipocytes': '2.1', 'Melanocytes': '0.335', 'Fibroblasts': '6.5', 'Peritubular cells': '0.210', 'Endometrial stromal cells': '27.7', 'Ovarian stromal cells': '0.7', 'Undifferentiated cells': '101.6', 'T-cells': '2.9', 'B-cells': '4.4', 'Plasma cells': '6.1', 'Nk-cells': '0.0', 'Granulocytes': '8.4', 'Monocytes': '0.0', 'Macrophages': '6.0', 'Hofbauer cells': '4.3', 'Kupffer cells': '1.0', 'Dendritic cells': '5.9', 'Langerhans cells': '0.304', 'Erythroid cells': '0.036', 'Adipocytes (Subcutaneous)': '-0.081', 'Adipocytes (Visceral)': '-0.209', 'Breast glandular cells (progenitors)': '0.538', 'Adipocytes (Breast)': '-0.689', 'Colon enterocytes': '0.790', 'Colon enteroendocrine cells': '0.112', 'Enteric glia cells': '-0.048', 'Mitotic cells (Colon)': '0.299', 'Mitotic cells (Heart)': '0.120', 'Podocytes': '-0.118', 'Ascending Loop of Henle cells': '0.475', 'Intercalated cells': '0.212', 'Cholangiocyte': '0.090', 'NK-cells (Liver)': '-0.005', 'Respiratory ciliated cells': '-0.012', 'Mitotic cells (Lung)': '0.071', 'NK-cells (Lung)': '-0.266', 'B-cells (Lung)': '-0.296', 'Alpha cells': '0.270', 'Beta cells': '0.152', 'Prostate glandular cells': '0.764', 'Prostate basal glandular cells': '0.540', 'Urothelial cells': '0.205', 'Keratinocyte (other)': '0.510', 'Keratinocyte (granular)': '0.055', 'Hair cortex cells': '0.080', 'Inner root sheath cells': '0.131', 'Outer root sheath cells': '0.175', 'Sebaceous gland cells': '0.156', 'Eccrine sweat gland cells': '-0.207', 'Adipocytes (Skin)': '-0.244', 'Mitotic cells (Skin)': '0.442', 'Parietal cells': '0.654', 'Chief cells': '0.649', 'Gastric mucous cells': '0.781', 'Gastric enteroendocrine cells': '0.590', 'Mitotic cells (Stomach)': '0.445', 'Parafollicular cells': '0.173', 'Thyroid glandular cells': '0.865', 'Mitotic cells (Thyroid)': '-0.081', 'Adrenal cortex cells': '0.051', 'Adrenal medulla cells': '0.087', 'Mitotic cells (Adrenal gland)': '0.072', 'Minor salivary glandular cells': '0.371', 'Minor salivary gland ductal cells': '-0.142', 'Minor salivary gland basal cells': '0.582', 'Mitotic cells (Minor salivary gland)': '0.567', 'Adipocytes (Minor salivary gland)': '0.050', 'Somatotropes': '0.121', 'Lactotropes': '0.322', 'Gonadotropes': '0.330', 'Corticotropes': '0.180', 'Thyrotropes': '0.496', 'Undifferentiated cells (Pituitary gland)': '-0.108', 'Mitotic cells (Spleen)': '-0.228', 'Platelets': '-0.050', 'Erythrocytes': '-0.158', 'Hematopoietic stem cells': '-0.211', 'B-cells (Spleen)': '0.266', 'NK-cells (Spleen)': '0.309', 'Amygdala excitatory': '1.0', 'Cerebellar inhibitory': '0.9', 'Cge interneuron': '0.7', 'Deep-layer corticothalamic and 6b': '1.5', 'Deep-layer intratelencephalic': '0.7', 'Deep-layer near-projecting': '0.7', 'Eccentric medium spiny neuron': '0.6', 'Hippocampal ca1-3': '1.9', 'Hippocampal ca4': '1.2', 'Hippocampal dentate gyrus': '1.1', 'Lamp5-lhx6 and chandelier': '0.5', 'Lower rhombic lip': '0.8', 'Mammillary body': '0.6', 'Medium spiny neuron': '0.7', 'Mge interneuron': '1.7', 'Midbrain-derived inhibitory': '0.7', 'Miscellaneous': '0.9', 'Splatter': '3.8', 'Thalamic excitatory': '0.5', 'Upper rhombic lip': '0.8', 'Upper-layer intratelencephalic': '0.6', 'Astrocyte': '4.4', 'Bergmann glia': '0.2', 'Central nervous system macrophage': '0.6', 'Choroid plexus epithelial cell': '52.1', 'Committed oligodendrocyte precursor': '41.5', 'Ependymal cell': '4.8', 'Oligodendrocyte': '53.1', 'Oligodendrocyte precursor cell': '2.4', 'Endothelial cell': '0.7', 'Pericyte': '0.3', 'Vascular associated smooth muscle cell': '0.0', 'Fibroblast': '17.4', 'Leukocyte': '1.1', 'Basophil': '0.0', 'Eosinophil': '0.0', 'Neutrophil': '0.0', 'Classical monocyte': '0.0', 'Non-classical monocyte': '0.0', 'Intermediate monocyte': '0.0', 'T-reg': '2.3', 'GdT-cell': '0.0', 'MAIT T-cell': '0.0', 'Memory CD4 T-cell': '0.0', 'Naive CD4 T-cell': '0.1', 'Memory CD8 T-cell': '0.2', 'Naive CD8 T-cell': '0.3', 'Memory B-cell': '0.0', 'Naive B-cell': '0.1', 'Plasmacytoid DC': '46.6', 'Myeloid DC': '8.5', 'NK-cell': '0.1', 'Total PBMC': '0.7', 'Vd2 gdTCR': '0.0', 'Memory CD4 T-cell Th1\\/Th17': '0.1', 'Memory CD4 T-cell Th17': '0.2', 'Memory CD4 T-cell Th2': '2.9', 'Non-Vd2 gdTCR': '0.1', 'Memory CD4 T-cell Th1': '0.3', 'Memory CD4 T-cell TFH': '0.5', 'Terminal effector memory CD4 T-cell': '0.0', 'Central memory CD8 T-cell': '4.8', 'Effector memory CD8 T-cell': '0.0', 'Terminal effector memory CD8 T-cell': '0.6', 'Non-switched memory B-cell': '0.0', 'Plasmablast': '3.3', 'Switched memory B-cell': '0.0', 'Exhausted memory B-cell': '0.7', 'Progenitor cell': '2.3', 'Memory T-reg': '1.3', 'Naive CD4 T-cell activated': '0.3', 'Naive CD8 T-cell activated': '0.6', 'Naive T-reg': '0.1'}
1O6S, 2O72, 2OMT, 2OMU, 2OMV, 2OMX, 2OMY, 2OMZ, 3FF7, 3FF8, 3L6X, 3L6Y, 4ZT1, 4ZTE, 6CXY, 6OLE, 6OLF, 6OLG, 6VEL, 7STZ, 8H62
{'Adipose Tissue': 1.2125261088039867, 'Adrenal Gland': 0.1914223992248062, 'Bladder': 39.2033519047619, 'Blood': 1.340954264800861, 'Blood Vessel': 0.3121561692883895, 'Brain': 0.8550442199091597, 'Breast': 38.54918344226579, 'Cervix Uteri': 23.539115789473684, 'Colon': 43.41292142490372, 'Esophagus': 53.97513367404844, 'Fallopian Tube': 14.900277777777776, 'Heart': 0.119140469221835, 'Kidney': 25.040449438202245, 'Liver': 26.60802654867257, 'Lung': 35.447986366782004, 'Muscle': 0.1378936151930261, 'Nerve': 17.518468982229404, 'Ovary': 3.6515122222222223, 'Pancreas': 56.89676829268293, 'Pituitary': 24.68741660777385, 'Prostate': 61.279967346938776, 'Salivary Gland': 92.01685185185184, 'Skin': 79.77571720232172, 'Small Intestine': 71.7519320855615, 'Spleen': 10.061029045643156, 'Stomach': 58.07813805013927, 'Testis': 0.8144204986149585, 'Thyroid': 135.176797856049, 'Uterus': 1.442593943661972, 'Vagina': 86.52345512820513}
SGO1
MAKERCLKKSFQDSLEDIKKRMKEKRNKNLAEIGKRRSFIAAPCQIITNTSTLLKNYQDNNKMLVLALENEKSKVKEAQDIILQLRKECYYLTCQLYALKGKLTSQQTVEPAQNQEICSSGMDPNSDDSSRNLFVKDLPQIPLEETELPGQGESFQIEDQIPTIPQDTLGVDFDSGEAKSTDNVLPRTVSVRSSLKKHCNSICQFDSLDDFETSHLAGKSFEFERVGFLDPLVNMHIPENVQHNACQWSKDQVNLSPKLIQPGTFTKTKEDILESKSEQTKSKQRDTQERKREEKRKANRRKSKRMSKYKENKSENKKTVPQKKMHKSVSSNDAYNFNLEEGVHLTPFRQKVSNDSNREENNESEVSLCESSGSGDDSDDLYLPTCKYIQNPTSNSDRPVTRPLAKRALKYTDEKETEGSKPTKTPTTTPPETQQSPHLSLKDITNVSLYPVVKIRRLSLSPKKNKASPAVALPKRRCTASVNYKEPTLASKLRRGDPFTDLCFLNSPIFKQKKDLRRSKKRALEVSPAKEAIFILYYVREFVSRFPDCRKCKLETHICLR
Homo sapiens
Nucleus, Chromosome, centromere, Chromosome, centromere, kinetochore, Cytoplasm, cytoskeleton, spindle pole, Cytoplasm, cytoskeleton, microtubule organizing center, centrosome
Tissue enhanced (bone marrow, lymphoid tissue, testis)
{'Ciliated cells': '1.3', 'Basal respiratory cells': '4.6', 'Club cells': '1.9', 'Ionocytes': '2.2', 'Mucus glandular cells': '1.3', 'Serous glandular cells': '0.1', 'Gastric mucus-secreting cells': '5.3', 'Proximal enterocytes': '2.2', 'Paneth cells': '0.5', 'Distal enterocytes': '1.2', 'Intestinal goblet cells': '5.9', 'Exocrine glandular cells': '-0.306', 'Basal prostatic cells': '0.0', 'Prostatic glandular cells': '0.0', 'Breast glandular cells': '0.181', 'Breast myoepithelial cells': '0.167', 'Glandular and luminal cells': '3.0', 'Secretory cells': '0.8', 'Basal keratinocytes': '6.4', 'Suprabasal keratinocytes': '2.5', 'Basal squamous epithelial cells': '2.4', 'Squamous epithelial cells': '8.6', 'Alveolar cells type 1': '-0.232', 'Alveolar cells type 2': '-0.026', 'Salivary duct cells': '1.6', 'Ductal cells': '0.397', 'Hepatocytes': '0.360', 'Cholangiocytes': '0.0', 'Proximal tubular cells': '0.276', 'Distal tubular cells': '0.0', 'Collecting duct cells': '1.9', 'Mesothelial cells': '0.054', 'Sertoli cells': '-0.084', 'Granulosa cells': '6.3', 'Enteroendocrine cells': '0.9', 'Pancreatic endocrine cells': '3.4', 'Leydig cells': '-0.082', 'Excitatory neurons': '0.1', 'Inhibitory neurons': '0.2', 'Cone photoreceptor cells': '0.0', 'Rod photoreceptor cells': '0.3', 'Bipolar cells': '0.2', 'Horizontal cells': '1.3', 'Astrocytes': '0.0', 'Oligodendrocyte precursor cells': '1.9', 'Oligodendrocytes': '1.0', 'Microglial cells': '0.0', 'Muller glia cells': '0.1', 'Schwann cells': '0.137', 'Spermatogonia': '0.335', 'Spermatocytes': '0.737', 'Early spermatids': '0.493', 'Late spermatids': '0.041', 'Oocytes': '148.5', 'Cytotrophoblasts': '18.2', 'Syncytiotrophoblasts': '6.3', 'Extravillous trophoblasts': '47.8', 'Endothelial cells': '1.1', 'Lymphatic endothelial cells': '0.2', 'Cardiomyocytes': '0.330', 'Skeletal myocytes': '0.015', 'Smooth muscle cells': '1.2', 'Adipocytes': '0.1', 'Melanocytes': '0.431', 'Fibroblasts': '1.9', 'Peritubular cells': '-0.057', 'Endometrial stromal cells': '1.1', 'Ovarian stromal cells': '1.3', 'Undifferentiated cells': '26.5', 'T-cells': '2.9', 'B-cells': '5.1', 'Plasma cells': '12.7', 'Nk-cells': '1.8', 'Granulocytes': '1.2', 'Monocytes': '0.0', 'Macrophages': '2.9', 'Hofbauer cells': '7.4', 'Kupffer cells': '2.1', 'Dendritic cells': '12.3', 'Langerhans cells': '0.180', 'Erythroid cells': '0.061', 'Adipocytes (Subcutaneous)': '-0.060', 'Adipocytes (Visceral)': '-0.121', 'Breast glandular cells (progenitors)': '0.165', 'Adipocytes (Breast)': '-0.132', 'Colon enterocytes': '0.378', 'Colon enteroendocrine cells': '-0.031', 'Enteric glia cells': '-0.137', 'Mitotic cells (Colon)': '0.576', 'Mitotic cells (Heart)': '0.541', 'Podocytes': '-0.126', 'Ascending Loop of Henle cells': '0.343', 'Intercalated cells': '0.053', 'Cholangiocyte': '0.220', 'NK-cells (Liver)': '-0.123', 'Respiratory ciliated cells': '-0.002', 'Mitotic cells (Lung)': '0.723', 'NK-cells (Lung)': '0.040', 'B-cells (Lung)': '0.154', 'Alpha cells': '0.214', 'Beta cells': '0.126', 'Prostate glandular cells': '-0.081', 'Prostate basal glandular cells': '0.249', 'Urothelial cells': '0.282', 'Keratinocyte (other)': '0.266', 'Keratinocyte (granular)': '-0.239', 'Hair cortex cells': '0.109', 'Inner root sheath cells': '0.248', 'Outer root sheath cells': '0.283', 'Sebaceous gland cells': '0.084', 'Eccrine sweat gland cells': '0.030', 'Adipocytes (Skin)': '-0.175', 'Mitotic cells (Skin)': '0.830', 'Parietal cells': '0.259', 'Chief cells': '0.275', 'Gastric mucous cells': '0.632', 'Gastric enteroendocrine cells': '0.343', 'Mitotic cells (Stomach)': '0.828', 'Parafollicular cells': '0.000', 'Thyroid glandular cells': '-0.067', 'Mitotic cells (Thyroid)': '0.532', 'Adrenal cortex cells': '0.271', 'Adrenal medulla cells': '0.147', 'Mitotic cells (Adrenal gland)': '0.766', 'Minor salivary glandular cells': '0.147', 'Minor salivary gland ductal cells': '-0.281', 'Minor salivary gland basal cells': '0.623', 'Mitotic cells (Minor salivary gland)': '0.905', 'Adipocytes (Minor salivary gland)': '0.111', 'Somatotropes': '-0.098', 'Lactotropes': '-0.190', 'Gonadotropes': '-0.026', 'Corticotropes': '-0.183', 'Thyrotropes': '-0.086', 'Undifferentiated cells (Pituitary gland)': '0.212', 'Mitotic cells (Spleen)': '0.810', 'Platelets': '0.058', 'Erythrocytes': '0.191', 'Hematopoietic stem cells': '0.232', 'B-cells (Spleen)': '0.143', 'NK-cells (Spleen)': '-0.048', 'Amygdala excitatory': '0.1', 'Cerebellar inhibitory': '0.6', 'Cge interneuron': '0.2', 'Deep-layer corticothalamic and 6b': '0.1', 'Deep-layer intratelencephalic': '0.1', 'Deep-layer near-projecting': '0.1', 'Eccentric medium spiny neuron': '0.1', 'Hippocampal ca1-3': '0.1', 'Hippocampal ca4': '0.0', 'Hippocampal dentate gyrus': '0.2', 'Lamp5-lhx6 and chandelier': '0.2', 'Lower rhombic lip': '0.3', 'Mammillary body': '0.4', 'Medium spiny neuron': '0.1', 'Mge interneuron': '0.2', 'Midbrain-derived inhibitory': '0.2', 'Miscellaneous': '0.1', 'Splatter': '0.2', 'Thalamic excitatory': '0.2', 'Upper rhombic lip': '0.4', 'Upper-layer intratelencephalic': '0.2', 'Astrocyte': '0.5', 'Bergmann glia': '1.2', 'Central nervous system macrophage': '0.8', 'Choroid plexus epithelial cell': '0.9', 'Committed oligodendrocyte precursor': '1.9', 'Ependymal cell': '0.2', 'Oligodendrocyte': '2.3', 'Oligodendrocyte precursor cell': '3.9', 'Endothelial cell': '0.1', 'Pericyte': '0.8', 'Vascular associated smooth muscle cell': '0.2', 'Fibroblast': '0.2', 'Leukocyte': '2.4', 'Basophil': '2.7', 'Eosinophil': '1.4', 'Neutrophil': '2.6', 'Classical monocyte': '0.5', 'Non-classical monocyte': '0.6', 'Intermediate monocyte': '0.6', 'T-reg': '4.2', 'GdT-cell': '0.2', 'MAIT T-cell': '0.8', 'Memory CD4 T-cell': '0.6', 'Naive CD4 T-cell': '1.4', 'Memory CD8 T-cell': '0.7', 'Naive CD8 T-cell': '1.3', 'Memory B-cell': '8.9', 'Naive B-cell': '6.4', 'Plasmacytoid DC': '9.0', 'Myeloid DC': '1.7', 'NK-cell': '3.0', 'Total PBMC': '2.8', 'Vd2 gdTCR': '2.1', 'Memory CD4 T-cell TFH': '1.8', 'Memory CD4 T-cell Th2': '2.7', 'Memory CD4 T-cell Th17': '3.1', 'Memory CD4 T-cell Th1\\/Th17': '3.8', 'Non-Vd2 gdTCR': '1.8', 'Memory CD4 T-cell Th1': '2.2', 'Terminal effector memory CD4 T-cell': '4.0', 'Central memory CD8 T-cell': '3.7', 'Effector memory CD8 T-cell': '4.0', 'Terminal effector memory CD8 T-cell': '1.8', 'Switched memory B-cell': '7.5', 'Plasmablast': '9.1', 'Non-switched memory B-cell': '9.8', 'Exhausted memory B-cell': '11.1', 'Progenitor cell': '1.8', 'Memory T-reg': '3.7', 'Naive CD4 T-cell activated': '0.9', 'Naive CD8 T-cell activated': '0.8', 'Naive T-reg': '1.6'}
3FGA, 3Q6S, 4A0I, 7ZJS
{'Adipose Tissue': 0.1590088970099667, 'Adrenal Gland': 0.1418290310077519, 'Bladder': 0.1539180952380952, 'Blood': 2.4452151302475778, 'Blood Vessel': 0.1042752059925093, 'Brain': 0.0466814061317183, 'Breast': 0.1450223529411764, 'Cervix Uteri': 0.2226042105263157, 'Colon': 0.4398095571245186, 'Esophagus': 0.6844072588235294, 'Fallopian Tube': 0.0458188888888888, 'Heart': 0.0530769349593495, 'Kidney': 0.1279684269662921, 'Liver': 0.1789144292035398, 'Lung': 0.4154759515570934, 'Muscle': 0.0279542627646326, 'Nerve': 0.1321255735056543, 'Ovary': 0.1790431666666666, 'Pancreas': 0.0587302652439024, 'Pituitary': 0.0848520636042402, 'Prostate': 0.1763763265306122, 'Salivary Gland': 0.3865213456790123, 'Skin': 1.6242774184632394, 'Small Intestine': 1.2551138502673798, 'Spleen': 1.2569626556016598, 'Stomach': 0.4962633760445682, 'Testis': 5.466135180055401, 'Thyroid': 0.1662916018376722, 'Uterus': 0.1016457746478873, 'Vagina': 0.7459582051282051}
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[39.62, 48.11, 57.93, 54.26, 55.97, 55.27, 66.15, 70.68, 76.45, 82.91, 80.91, 88.91, 87.63, 89.46, 92.5, 91.23, 91.74, 92.14, 94.69, 92.67, 93.74, 93.21, 92.83, 90.91, 91.83, 88.85, 86.96, 87.95, 79.84, 78.45, 77.83, 74.73, 61.79, 59.65, 62.7, 59.23, 52.26, 52.67, 56.89, 52.53, 47.32, 53.73, 49.54, 47.53, 54.99, 53.81, 54.59, 60.11, 71.66, 80.16, 84.51, 83.99, 86.47, 90.75, 92.19, 91.4, 92.36, 95.59, 94.34, 95.58, 96.65, 97.32, 95.66, 97.61, 97.05, 97.22, 96.32, 97.64, 96.92, 96.91, 96.3, 97.86, 95.71, 97.37, 97.88, 97.64, 97.55, 98.13, 98.29, 97.76, 98.04, 97.83, 97.78, 98.04, 98.51, 98.18, 97.58, 97.55, 97.24, 97.61, 97.4, 97.79, 96.91, 95.94, 96.04, 96.06, 94.75, 94.41, 94.35, 94.26, 90.62, 92.14, 87.62, 83.51, 79.53, 71.35, 64.82, 56.44, 57.74, 42.91, 44.17, 43.48, 48.35, 42.23, 42.2, 37.39, 39.01, 40.09, 47.16, 41.83, 50.29, 54.49, 47.13, 47.54, 50.66, 55.78, 48.81, 51.5, 47.69, 50.83, 46.53, 47.81, 44.93, 39.73, 41.95, 45.42, 37.51, 38.07, 38.31, 33.07, 35.67, 31.64, 31.81, 38.9, 30.11, 36.4, 34.64, 33.43, 34.93, 31.68, 36.68, 36.06, 37.17, 32.84, 36.43, 36.86, 43.13, 37.95, 40.45, 38.34, 36.12, 38.62, 37.6, 35.77, 39.3, 37.31, 39.61, 46.01, 41.05, 39.68, 44.37, 47.82, 35.56, 45.7, 37.19, 51.9, 37.16, 42.82, 43.47, 37.47, 41.09, 39.63, 47.82, 41.13, 52.01, 44.78, 41.71, 40.61, 42.14, 45.48, 42.21, 41.09, 37.57, 42.62, 40.31, 38.23, 45.96, 36.85, 36.04, 34.1, 41.57, 34.69, 34.58, 37.34, 37.8, 40.3, 33.64, 45.97, 40.27, 46.93, 36.32, 43.34, 36.38, 40.11, 34.57, 41.78, 37.19, 35.84, 35.54, 31.61, 36.98, 37.48, 36.12, 32.97, 33.06, 35.58, 36.29, 32.11, 41.25, 32.81, 44.57, 39.19, 38.72, 36.86, 38.09, 37.02, 39.5, 44.19, 35.16, 36.25, 39.26, 39.44, 34.28, 32.72, 40.79, 37.45, 38.18, 35.5, 43.85, 45.69, 46.33, 44.88, 41.7, 40.4, 46.55, 37.1, 49.71, 41.36, 39.19, 38.16, 34.22, 39.03, 41.16, 33.59, 33.11, 41.43, 37.28, 41.93, 38.05, 39.55, 38.52, 43.23, 43.73, 30.99, 40.14, 32.49, 45.59, 36.94, 39.57, 36.7, 40.54, 46.08, 37.62, 36.26, 36.32, 40.0, 41.86, 47.2, 45.76, 48.92, 44.89, 49.42, 48.48, 47.65, 46.89, 50.54, 49.39, 47.55, 45.89, 44.92, 45.04, 38.44, 46.59, 38.98, 37.51, 36.89, 47.74, 40.98, 45.64, 44.32, 42.06, 49.98, 43.17, 50.2, 46.55, 44.13, 41.6, 41.59, 39.36, 41.45, 43.29, 42.52, 43.75, 45.52, 44.42, 36.81, 41.26, 40.31, 48.55, 46.65, 47.2, 51.61, 68.44, 65.71, 63.62, 68.26, 64.58, 64.74, 55.15, 54.01, 49.94, 55.42, 62.88, 59.77, 56.56, 57.14, 62.77, 53.56, 45.58, 55.07, 53.87, 49.11, 53.12, 39.69, 47.67, 49.12, 42.78, 47.23, 49.1, 50.6, 46.49, 48.42, 47.15, 48.28, 44.53, 40.06, 41.88, 38.52, 38.56, 38.53, 40.97, 41.87, 34.07, 39.74, 41.65, 45.55, 47.31, 47.2, 56.36, 61.79, 58.49, 58.58, 63.51, 42.78, 39.78, 45.81, 41.75, 43.36, 43.55, 43.87, 38.74, 42.71, 41.66, 43.02, 43.72, 43.29, 41.81, 40.19, 37.89, 48.1, 34.9, 42.21, 35.68, 35.33, 36.61, 43.5, 33.44, 37.28, 40.94, 39.57, 36.09, 38.23, 42.95, 44.61, 47.38, 44.87, 52.19, 45.42, 42.51, 48.44, 47.97, 50.3, 39.9, 46.33, 36.68, 44.08, 31.62, 40.03, 39.23, 43.24, 42.79, 31.06, 35.68, 36.59, 36.13, 39.07, 44.95, 45.27, 45.95, 52.24, 58.13, 62.17, 56.54, 66.38, 58.84, 57.29, 51.24, 50.38, 48.69, 50.16, 51.28, 48.26, 49.18, 48.95, 48.74, 42.58, 41.79, 39.61, 40.42, 41.16, 37.83, 47.33, 48.25, 44.65, 47.69, 40.84, 37.33, 45.27, 41.53, 36.41, 46.85, 42.46, 54.44, 49.41, 55.22, 57.53, 51.78, 50.22, 62.39, 62.64, 64.07, 63.79, 65.81, 67.99, 70.25, 69.12, 69.48, 75.41, 78.24, 81.76, 72.76, 75.49, 72.3, 73.13, 69.87, 68.68, 73.55, 70.61, 67.61, 65.15, 67.4, 70.36, 64.39, 60.89, 62.55, 58.5, 52.8, 63.59, 58.73, 55.98, 59.31, 58.37, 58.44, 59.17, 49.77, 56.65, 54.7, 46.63, 53.01, 53.02, 56.79, 53.94, 54.98, 61.59, 62.33, 66.63, 74.98, 78.8, 81.3, 81.72, 81.89, 84.81, 86.98, 87.98, 87.41, 87.26, 89.35, 86.84, 85.66, 85.0, 84.83, 82.57, 80.09, 81.56, 83.74, 77.83, 73.52, 73.48, 69.88, 67.7, 68.02, 62.4, 63.24, 65.02, 64.77, 65.2, 65.05, 70.27, 65.12, 68.52, 61.5]
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null
Component of an E-cadherin/ catenin adhesion complex composed of at least E-cadherin/CDH1, beta-catenin/CTNNB1 or gamma-catenin/JUP, and potentially alpha-catenin/CTNNA1. Forms a ternary complex composed of ADAM10, CADH1 and EPHA4,
null
null
KLRG1, SPEF1, DLGAP5, AJAP1, RAPGEF2, RAB8B, PIP5K1C, PKP2, TRPV4, CTNNB1, CAV1, DDR1, TBC1D2, CTNNA1, JUP, CTNND1, PSEN1, LIMA1, CDH1, JUP, ADAM10, CADH1 , EPHA4,
null
null
null
null
Homodimer
null
79.91949
0.474025
54.806613
0.821729
1,381
P12830
Q6UVJ0
null
degron_data
CDH1
MGPWSRSLSALLLLLQVSSWLCQEPEPCHPGFDAESYTFTVPRRHLERGRVLGRVNFEDCTGRQRTAYFSLDTRFKVGTDGVITVKRPLRFHNPQIHFLVYAWDSTYRKFSTKVTLNTVGHHHRPPPHQASVSGIQAELLTFPNSSPGLRRQKRDWVIPPISCPENEKGPFPKNLVQIKSNKDKEGKVFYSITGQGADTPPVGVFIIERETGWLKVTEPLDRERIATYTLFSHAVSSNGNAVEDPMEILITVTDQNDNKPEFTQEVFKGSVMEGALPGTSVMEVTATDADDDVNTYNAAIAYTILSQDPELPDKNMFTINRNTGVISVVTTGLDRESFPTYTLVVQAADLQGEGLSTTATAVITVTDTNDNPPIFNPTTYKGQVPENEANVVITTLKVTDADAPNTPAWEAVYTILNDDGGQFVVTTNPVNNDGILKTAKGLDFEAKQQYILHVAVTNVVPFEVSLTTSTATVTVDVLDVNEAPIFVPPEKRVEVSEDFGVGQEITSYTAQEPDTFMEQKITYRIWRDTANWLEINPDTGAISTRAELDREDFEHVKNSTYTALIIATDNGSPVATGTGTLLLILSDVNDNAPIPEPRTIFFCERNPKPQVINIIDADLPPNTSPFTAELTHGASANWTIQYNDPTQESIILKPKMALEVGDYKINLKLMDNQNKDQVTTLEVSVCDCEGAAGVCRKAQPVEAGLQIPAILGILGGILALLILILLLLLFLRRRAVVKEPLLPPEDDTRDNVYYYDEEGGGEEDQDFDLSQLHRGLDARPEVTRNDVAPTLMSVPRYLPRPANPDEIGNFIDENLKAADTDPTAPPYDSLLVFDYEGSGSEAASLSSLNSSESDKDQDYDYLNEWGNRFKKLADMYGGGEDD
Homo sapiens
Cell junction, adherens junction, Cell membrane, Endosome, Golgi apparatus, trans-Golgi network, Cytoplasm, Cell junction, desmosome
Tissue enhanced (parathyroid)
{'Ciliated cells': '119.1', 'Basal respiratory cells': '71.1', 'Club cells': '97.3', 'Ionocytes': '81.0', 'Mucus glandular cells': '155.0', 'Serous glandular cells': '67.8', 'Gastric mucus-secreting cells': '133.2', 'Proximal enterocytes': '140.9', 'Paneth cells': '125.1', 'Distal enterocytes': '307.5', 'Intestinal goblet cells': '173.5', 'Exocrine glandular cells': '-0.605', 'Basal prostatic cells': '68.3', 'Prostatic glandular cells': '186.7', 'Breast glandular cells': '0.773', 'Breast myoepithelial cells': '0.700', 'Glandular and luminal cells': '313.0', 'Secretory cells': '82.3', 'Basal keratinocytes': '102.5', 'Suprabasal keratinocytes': '162.6', 'Basal squamous epithelial cells': '51.0', 'Squamous epithelial cells': '106.9', 'Alveolar cells type 1': '0.437', 'Alveolar cells type 2': '0.706', 'Salivary duct cells': '95.9', 'Ductal cells': '0.541', 'Hepatocytes': '0.600', 'Cholangiocytes': '129.7', 'Proximal tubular cells': '0.042', 'Distal tubular cells': '0.0', 'Collecting duct cells': '143.9', 'Mesothelial cells': '0.799', 'Sertoli cells': '0.252', 'Granulosa cells': '12.9', 'Enteroendocrine cells': '92.4', 'Pancreatic endocrine cells': '78.1', 'Leydig cells': '0.264', 'Excitatory neurons': '0.7', 'Inhibitory neurons': '1.3', 'Cone photoreceptor cells': '0.0', 'Rod photoreceptor cells': '0.0', 'Bipolar cells': '0.2', 'Horizontal cells': '0.6', 'Astrocytes': '0.6', 'Oligodendrocyte precursor cells': '0.5', 'Oligodendrocytes': '29.9', 'Microglial cells': '0.9', 'Muller glia cells': '0.1', 'Schwann cells': '0.131', 'Spermatogonia': '0.392', 'Spermatocytes': '0.193', 'Early spermatids': '-0.217', 'Late spermatids': '-0.290', 'Oocytes': '16.9', 'Cytotrophoblasts': '119.2', 'Syncytiotrophoblasts': '45.0', 'Extravillous trophoblasts': '24.9', 'Endothelial cells': '6.1', 'Lymphatic endothelial cells': '0.4', 'Cardiomyocytes': '0.135', 'Skeletal myocytes': '0.107', 'Smooth muscle cells': '5.8', 'Adipocytes': '2.1', 'Melanocytes': '0.335', 'Fibroblasts': '6.5', 'Peritubular cells': '0.210', 'Endometrial stromal cells': '27.7', 'Ovarian stromal cells': '0.7', 'Undifferentiated cells': '101.6', 'T-cells': '2.9', 'B-cells': '4.4', 'Plasma cells': '6.1', 'Nk-cells': '0.0', 'Granulocytes': '8.4', 'Monocytes': '0.0', 'Macrophages': '6.0', 'Hofbauer cells': '4.3', 'Kupffer cells': '1.0', 'Dendritic cells': '5.9', 'Langerhans cells': '0.304', 'Erythroid cells': '0.036', 'Adipocytes (Subcutaneous)': '-0.081', 'Adipocytes (Visceral)': '-0.209', 'Breast glandular cells (progenitors)': '0.538', 'Adipocytes (Breast)': '-0.689', 'Colon enterocytes': '0.790', 'Colon enteroendocrine cells': '0.112', 'Enteric glia cells': '-0.048', 'Mitotic cells (Colon)': '0.299', 'Mitotic cells (Heart)': '0.120', 'Podocytes': '-0.118', 'Ascending Loop of Henle cells': '0.475', 'Intercalated cells': '0.212', 'Cholangiocyte': '0.090', 'NK-cells (Liver)': '-0.005', 'Respiratory ciliated cells': '-0.012', 'Mitotic cells (Lung)': '0.071', 'NK-cells (Lung)': '-0.266', 'B-cells (Lung)': '-0.296', 'Alpha cells': '0.270', 'Beta cells': '0.152', 'Prostate glandular cells': '0.764', 'Prostate basal glandular cells': '0.540', 'Urothelial cells': '0.205', 'Keratinocyte (other)': '0.510', 'Keratinocyte (granular)': '0.055', 'Hair cortex cells': '0.080', 'Inner root sheath cells': '0.131', 'Outer root sheath cells': '0.175', 'Sebaceous gland cells': '0.156', 'Eccrine sweat gland cells': '-0.207', 'Adipocytes (Skin)': '-0.244', 'Mitotic cells (Skin)': '0.442', 'Parietal cells': '0.654', 'Chief cells': '0.649', 'Gastric mucous cells': '0.781', 'Gastric enteroendocrine cells': '0.590', 'Mitotic cells (Stomach)': '0.445', 'Parafollicular cells': '0.173', 'Thyroid glandular cells': '0.865', 'Mitotic cells (Thyroid)': '-0.081', 'Adrenal cortex cells': '0.051', 'Adrenal medulla cells': '0.087', 'Mitotic cells (Adrenal gland)': '0.072', 'Minor salivary glandular cells': '0.371', 'Minor salivary gland ductal cells': '-0.142', 'Minor salivary gland basal cells': '0.582', 'Mitotic cells (Minor salivary gland)': '0.567', 'Adipocytes (Minor salivary gland)': '0.050', 'Somatotropes': '0.121', 'Lactotropes': '0.322', 'Gonadotropes': '0.330', 'Corticotropes': '0.180', 'Thyrotropes': '0.496', 'Undifferentiated cells (Pituitary gland)': '-0.108', 'Mitotic cells (Spleen)': '-0.228', 'Platelets': '-0.050', 'Erythrocytes': '-0.158', 'Hematopoietic stem cells': '-0.211', 'B-cells (Spleen)': '0.266', 'NK-cells (Spleen)': '0.309', 'Amygdala excitatory': '1.0', 'Cerebellar inhibitory': '0.9', 'Cge interneuron': '0.7', 'Deep-layer corticothalamic and 6b': '1.5', 'Deep-layer intratelencephalic': '0.7', 'Deep-layer near-projecting': '0.7', 'Eccentric medium spiny neuron': '0.6', 'Hippocampal ca1-3': '1.9', 'Hippocampal ca4': '1.2', 'Hippocampal dentate gyrus': '1.1', 'Lamp5-lhx6 and chandelier': '0.5', 'Lower rhombic lip': '0.8', 'Mammillary body': '0.6', 'Medium spiny neuron': '0.7', 'Mge interneuron': '1.7', 'Midbrain-derived inhibitory': '0.7', 'Miscellaneous': '0.9', 'Splatter': '3.8', 'Thalamic excitatory': '0.5', 'Upper rhombic lip': '0.8', 'Upper-layer intratelencephalic': '0.6', 'Astrocyte': '4.4', 'Bergmann glia': '0.2', 'Central nervous system macrophage': '0.6', 'Choroid plexus epithelial cell': '52.1', 'Committed oligodendrocyte precursor': '41.5', 'Ependymal cell': '4.8', 'Oligodendrocyte': '53.1', 'Oligodendrocyte precursor cell': '2.4', 'Endothelial cell': '0.7', 'Pericyte': '0.3', 'Vascular associated smooth muscle cell': '0.0', 'Fibroblast': '17.4', 'Leukocyte': '1.1', 'Basophil': '0.0', 'Eosinophil': '0.0', 'Neutrophil': '0.0', 'Classical monocyte': '0.0', 'Non-classical monocyte': '0.0', 'Intermediate monocyte': '0.0', 'T-reg': '2.3', 'GdT-cell': '0.0', 'MAIT T-cell': '0.0', 'Memory CD4 T-cell': '0.0', 'Naive CD4 T-cell': '0.1', 'Memory CD8 T-cell': '0.2', 'Naive CD8 T-cell': '0.3', 'Memory B-cell': '0.0', 'Naive B-cell': '0.1', 'Plasmacytoid DC': '46.6', 'Myeloid DC': '8.5', 'NK-cell': '0.1', 'Total PBMC': '0.7', 'Vd2 gdTCR': '0.0', 'Memory CD4 T-cell Th1\\/Th17': '0.1', 'Memory CD4 T-cell Th17': '0.2', 'Memory CD4 T-cell Th2': '2.9', 'Non-Vd2 gdTCR': '0.1', 'Memory CD4 T-cell Th1': '0.3', 'Memory CD4 T-cell TFH': '0.5', 'Terminal effector memory CD4 T-cell': '0.0', 'Central memory CD8 T-cell': '4.8', 'Effector memory CD8 T-cell': '0.0', 'Terminal effector memory CD8 T-cell': '0.6', 'Non-switched memory B-cell': '0.0', 'Plasmablast': '3.3', 'Switched memory B-cell': '0.0', 'Exhausted memory B-cell': '0.7', 'Progenitor cell': '2.3', 'Memory T-reg': '1.3', 'Naive CD4 T-cell activated': '0.3', 'Naive CD8 T-cell activated': '0.6', 'Naive T-reg': '0.1'}
1O6S, 2O72, 2OMT, 2OMU, 2OMV, 2OMX, 2OMY, 2OMZ, 3FF7, 3FF8, 3L6X, 3L6Y, 4ZT1, 4ZTE, 6CXY, 6OLE, 6OLF, 6OLG, 6VEL, 7STZ, 8H62
{'Adipose Tissue': 1.2125261088039867, 'Adrenal Gland': 0.1914223992248062, 'Bladder': 39.2033519047619, 'Blood': 1.340954264800861, 'Blood Vessel': 0.3121561692883895, 'Brain': 0.8550442199091597, 'Breast': 38.54918344226579, 'Cervix Uteri': 23.539115789473684, 'Colon': 43.41292142490372, 'Esophagus': 53.97513367404844, 'Fallopian Tube': 14.900277777777776, 'Heart': 0.119140469221835, 'Kidney': 25.040449438202245, 'Liver': 26.60802654867257, 'Lung': 35.447986366782004, 'Muscle': 0.1378936151930261, 'Nerve': 17.518468982229404, 'Ovary': 3.6515122222222223, 'Pancreas': 56.89676829268293, 'Pituitary': 24.68741660777385, 'Prostate': 61.279967346938776, 'Salivary Gland': 92.01685185185184, 'Skin': 79.77571720232172, 'Small Intestine': 71.7519320855615, 'Spleen': 10.061029045643156, 'Stomach': 58.07813805013927, 'Testis': 0.8144204986149585, 'Thyroid': 135.176797856049, 'Uterus': 1.442593943661972, 'Vagina': 86.52345512820513}
SASS6
MSQVLFHQLVPLQVKCKDCEERRVSIRMSIELQSVSNPVHRKDLVIRLTDDTDPFFLYNLVISEEDFQSLKFQQGLLVDFLAFPQKFIDLLQQCTQEHAKEIPRFLLQLVSPAAILDNSPAFLNVVETNPFKHLTHLSLKLLPGNDVEIKKFLAGCLKCSKEEKLSLMQSLDDATKQLDFTRKTLAEKKQELDKLRNEWASHTAALTNKHSQELTNEKEKALQAQVQYQQQHEQQKKDLEILHQQNIHQLQNRLSELEAANKDLTERKYKGDSTIRELKAKLSGVEEELQRTKQEVLSLRRENSTLDVECHEKEKHVNQLQTKVAVLEQEIKDKDQLVLRTKEAFDTIQEQKVVLEENGEKNQVQLGKLEATIKSLSAELLKANEIIKKLQGDLKTLMGKLKLKNTVTIQQEKLLAEKEEKLQKEQKELQDVGQSLRIKEQEVCKLQEQLEATVKKLEESKQLLKNNEKLITWLNKELNENQLVRKQDVLGPSTTPPAHSSSNTIRSGISPNLNVVDGRLTYPTCGIGYPVSSAFAFQNTFPHSISAKNTSHPGSGTKVQFNLQFTKPNASLGDVQSGATISMPCSTDKENGENVGLESKYLKKREDSIPLRGLSQNLFSNSDHQRDGTLGALHTSSKPTALPSASSAYFPGQLPNS
Homo sapiens
Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriole
Low tissue specificity
{'Ciliated cells': '6.1', 'Basal respiratory cells': '6.5', 'Club cells': '5.8', 'Ionocytes': '4.0', 'Mucus glandular cells': '5.3', 'Serous glandular cells': '3.9', 'Gastric mucus-secreting cells': '7.1', 'Proximal enterocytes': '2.4', 'Paneth cells': '1.8', 'Distal enterocytes': '1.7', 'Intestinal goblet cells': '6.1', 'Exocrine glandular cells': '-0.518', 'Basal prostatic cells': '6.6', 'Prostatic glandular cells': '9.2', 'Breast glandular cells': '0.599', 'Breast myoepithelial cells': '0.567', 'Glandular and luminal cells': '5.6', 'Secretory cells': '6.7', 'Basal keratinocytes': '7.5', 'Suprabasal keratinocytes': '5.8', 'Basal squamous epithelial cells': '6.9', 'Squamous epithelial cells': '12.1', 'Alveolar cells type 1': '-0.095', 'Alveolar cells type 2': '-0.084', 'Salivary duct cells': '8.3', 'Ductal cells': '0.463', 'Hepatocytes': '0.168', 'Cholangiocytes': '9.5', 'Proximal tubular cells': '0.018', 'Distal tubular cells': '3.1', 'Collecting duct cells': '1.9', 'Mesothelial cells': '0.325', 'Sertoli cells': '0.112', 'Granulosa cells': '12.1', 'Enteroendocrine cells': '7.3', 'Pancreatic endocrine cells': '1.7', 'Leydig cells': '0.014', 'Excitatory neurons': '7.3', 'Inhibitory neurons': '9.2', 'Cone photoreceptor cells': '15.3', 'Rod photoreceptor cells': '19.9', 'Bipolar cells': '17.3', 'Horizontal cells': '7.6', 'Astrocytes': '8.1', 'Oligodendrocyte precursor cells': '4.7', 'Oligodendrocytes': '15.0', 'Microglial cells': '5.4', 'Muller glia cells': '10.8', 'Schwann cells': '0.091', 'Spermatogonia': '0.365', 'Spermatocytes': '0.704', 'Early spermatids': '0.421', 'Late spermatids': '-0.100', 'Oocytes': '171.3', 'Cytotrophoblasts': '14.6', 'Syncytiotrophoblasts': '6.1', 'Extravillous trophoblasts': '17.8', 'Endothelial cells': '6.5', 'Lymphatic endothelial cells': '5.2', 'Cardiomyocytes': '0.529', 'Skeletal myocytes': '-0.120', 'Smooth muscle cells': '5.7', 'Adipocytes': '6.5', 'Melanocytes': '0.062', 'Fibroblasts': '7.3', 'Peritubular cells': '0.055', 'Endometrial stromal cells': '5.5', 'Ovarian stromal cells': '10.0', 'Undifferentiated cells': '18.0', 'T-cells': '8.4', 'B-cells': '9.8', 'Plasma cells': '19.6', 'Nk-cells': '14.8', 'Granulocytes': '7.6', 'Monocytes': '3.9', 'Macrophages': '5.3', 'Hofbauer cells': '7.2', 'Kupffer cells': '5.6', 'Dendritic cells': '7.4', 'Langerhans cells': '0.128', 'Erythroid cells': '0.056', 'Adipocytes (Subcutaneous)': '-0.273', 'Adipocytes (Visceral)': '-0.352', 'Breast glandular cells (progenitors)': '0.429', 'Adipocytes (Breast)': '-0.603', 'Colon enterocytes': '-0.025', 'Colon enteroendocrine cells': '0.243', 'Enteric glia cells': '0.186', 'Mitotic cells (Colon)': '-0.066', 'Mitotic cells (Heart)': '0.472', 'Podocytes': '-0.071', 'Ascending Loop of Henle cells': '0.475', 'Intercalated cells': '-0.049', 'Cholangiocyte': '0.282', 'NK-cells (Liver)': '-0.160', 'Respiratory ciliated cells': '0.105', 'Mitotic cells (Lung)': '0.255', 'NK-cells (Lung)': '0.040', 'B-cells (Lung)': '-0.004', 'Alpha cells': '0.383', 'Beta cells': '0.236', 'Prostate glandular cells': '-0.089', 'Prostate basal glandular cells': '0.231', 'Urothelial cells': '0.158', 'Keratinocyte (other)': '-0.040', 'Keratinocyte (granular)': '-0.387', 'Hair cortex cells': '0.048', 'Inner root sheath cells': '0.149', 'Outer root sheath cells': '0.335', 'Sebaceous gland cells': '0.252', 'Eccrine sweat gland cells': '0.266', 'Adipocytes (Skin)': '0.077', 'Mitotic cells (Skin)': '0.449', 'Parietal cells': '-0.342', 'Chief cells': '-0.214', 'Gastric mucous cells': '0.018', 'Gastric enteroendocrine cells': '-0.069', 'Mitotic cells (Stomach)': '0.360', 'Parafollicular cells': '0.059', 'Thyroid glandular cells': '0.189', 'Mitotic cells (Thyroid)': '0.068', 'Adrenal cortex cells': '0.442', 'Adrenal medulla cells': '-0.048', 'Mitotic cells (Adrenal gland)': '0.360', 'Minor salivary glandular cells': '0.388', 'Minor salivary gland ductal cells': '0.200', 'Minor salivary gland basal cells': '0.210', 'Mitotic cells (Minor salivary gland)': '0.272', 'Adipocytes (Minor salivary gland)': '-0.018', 'Somatotropes': '0.263', 'Lactotropes': '0.276', 'Gonadotropes': '0.242', 'Corticotropes': '-0.023', 'Thyrotropes': '0.268', 'Undifferentiated cells (Pituitary gland)': '0.040', 'Mitotic cells (Spleen)': '0.295', 'Platelets': '-0.140', 'Erythrocytes': '0.025', 'Hematopoietic stem cells': '-0.078', 'B-cells (Spleen)': '0.277', 'NK-cells (Spleen)': '0.198', 'Amygdala excitatory': '7.8', 'Cerebellar inhibitory': '13.1', 'Cge interneuron': '11.7', 'Deep-layer corticothalamic and 6b': '8.8', 'Deep-layer intratelencephalic': '6.8', 'Deep-layer near-projecting': '16.9', 'Eccentric medium spiny neuron': '7.5', 'Hippocampal ca1-3': '7.2', 'Hippocampal ca4': '6.7', 'Hippocampal dentate gyrus': '10.5', 'Lamp5-lhx6 and chandelier': '10.9', 'Lower rhombic lip': '11.0', 'Mammillary body': '19.2', 'Medium spiny neuron': '5.7', 'Mge interneuron': '10.7', 'Midbrain-derived inhibitory': '19.6', 'Miscellaneous': '8.8', 'Splatter': '11.1', 'Thalamic excitatory': '9.7', 'Upper rhombic lip': '21.4', 'Upper-layer intratelencephalic': '7.9', 'Astrocyte': '11.7', 'Bergmann glia': '13.8', 'Central nervous system macrophage': '16.5', 'Choroid plexus epithelial cell': '10.1', 'Committed oligodendrocyte precursor': '10.7', 'Ependymal cell': '8.4', 'Oligodendrocyte': '21.4', 'Oligodendrocyte precursor cell': '12.5', 'Endothelial cell': '12.6', 'Pericyte': '8.3', 'Vascular associated smooth muscle cell': '7.0', 'Fibroblast': '11.0', 'Leukocyte': '17.2', 'Basophil': '6.6', 'Eosinophil': '1.0', 'Neutrophil': '2.4', 'Classical monocyte': '2.9', 'Non-classical monocyte': '6.6', 'Intermediate monocyte': '1.6', 'T-reg': '4.6', 'GdT-cell': '0.7', 'MAIT T-cell': '3.0', 'Memory CD4 T-cell': '0.8', 'Naive CD4 T-cell': '11.0', 'Memory CD8 T-cell': '0.7', 'Naive CD8 T-cell': '9.6', 'Memory B-cell': '1.6', 'Naive B-cell': '17.4', 'Plasmacytoid DC': '2.8', 'Myeloid DC': '2.7', 'NK-cell': '12.0', 'Total PBMC': '3.7', 'Vd2 gdTCR': '2.9', 'Memory CD4 T-cell Th1\\/Th17': '10.3', 'Memory CD4 T-cell Th17': '7.3', 'Memory CD4 T-cell Th2': '8.7', 'Non-Vd2 gdTCR': '4.5', 'Memory CD4 T-cell Th1': '8.3', 'Memory CD4 T-cell TFH': '7.0', 'Terminal effector memory CD4 T-cell': '2.0', 'Central memory CD8 T-cell': '5.0', 'Effector memory CD8 T-cell': '8.3', 'Terminal effector memory CD8 T-cell': '4.4', 'Non-switched memory B-cell': '3.5', 'Plasmablast': '5.6', 'Switched memory B-cell': '2.5', 'Exhausted memory B-cell': '9.5', 'Progenitor cell': '3.3', 'Memory T-reg': '7.3', 'Naive CD4 T-cell activated': '5.5', 'Naive CD8 T-cell activated': '5.7', 'Naive T-reg': '14.2'}
6YS4, 6Z4A
{'Adipose Tissue': 2.5515510797342196, 'Adrenal Gland': 1.9868732558139537, 'Bladder': 3.2903333333333338, 'Blood': 3.874495382131324, 'Blood Vessel': 2.6446337827715354, 'Brain': 2.205175094625284, 'Breast': 3.3008204793028324, 'Cervix Uteri': 4.666894736842106, 'Colon': 3.4950216944801027, 'Esophagus': 3.1430939100346023, 'Fallopian Tube': 4.358555555555555, 'Heart': 0.985506399535424, 'Kidney': 1.357713483146067, 'Liver': 1.0508296460176991, 'Lung': 2.761138581314879, 'Muscle': 1.2507969115815691, 'Nerve': 3.650915993537964, 'Ovary': 4.4900722222222225, 'Pancreas': 1.1732655487804875, 'Pituitary': 3.936876325088339, 'Prostate': 3.4814326530612245, 'Salivary Gland': 3.099225308641975, 'Skin': 3.3365613045881704, 'Small Intestine': 3.935122994652407, 'Spleen': 4.246087136929461, 'Stomach': 2.5671557103064067, 'Testis': 12.56194459833795, 'Thyroid': 3.6312125574272582, 'Uterus': 5.4675, 'Vagina': 4.1489102564102565}
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[67.49, 81.03, 89.76, 91.99, 95.13, 96.53, 94.45, 95.69, 94.86, 94.94, 93.53, 92.49, 91.69, 89.65, 87.9, 81.76, 76.26, 69.7, 67.7, 75.07, 80.03, 86.28, 87.48, 91.19, 92.58, 94.64, 95.56, 96.6, 96.3, 97.56, 94.83, 93.14, 89.63, 85.98, 76.15, 71.96, 60.94, 60.92, 63.19, 66.58, 79.79, 86.87, 93.35, 95.71, 95.24, 97.04, 95.52, 95.61, 94.36, 91.22, 89.86, 89.93, 88.83, 88.36, 88.41, 91.18, 93.63, 95.02, 95.34, 96.21, 94.71, 95.4, 92.62, 91.03, 91.84, 93.3, 95.08, 95.55, 95.26, 95.07, 95.27, 95.93, 95.91, 95.4, 94.74, 95.5, 94.89, 94.97, 94.34, 93.65, 92.48, 95.0, 96.68, 96.58, 96.6, 96.8, 97.51, 97.61, 97.53, 95.77, 96.34, 95.27, 94.44, 94.55, 93.26, 92.1, 91.34, 83.99, 84.72, 89.26, 86.01, 83.44, 88.54, 92.45, 94.92, 93.79, 95.42, 94.19, 93.38, 92.94, 88.42, 81.57, 78.34, 69.34, 65.74, 66.31, 69.21, 73.22, 86.42, 92.03, 92.68, 95.6, 96.75, 96.81, 97.37, 95.44, 95.13, 90.5, 87.38, 88.23, 91.49, 92.18, 89.91, 95.26, 95.15, 93.91, 97.17, 96.94, 96.86, 95.7, 95.16, 94.63, 92.9, 91.18, 91.75, 92.35, 94.62, 93.06, 92.97, 95.09, 93.2, 92.29, 94.04, 95.64, 92.14, 92.76, 94.75, 95.68, 93.2, 93.99, 97.31, 97.2, 96.85, 97.6, 97.38, 97.61, 97.85, 97.88, 97.42, 97.99, 97.82, 97.97, 97.89, 97.29, 98.03, 97.79, 98.17, 98.08, 98.24, 98.08, 97.56, 98.08, 98.26, 97.95, 98.08, 98.27, 97.96, 97.92, 98.25, 98.28, 98.25, 98.14, 98.21, 98.09, 97.96, 98.09, 97.97, 98.31, 97.64, 98.22, 98.08, 98.3, 98.07, 97.92, 98.36, 97.96, 98.19, 98.09, 98.33, 97.79, 98.21, 98.26, 98.31, 98.15, 97.43, 98.08, 97.65, 98.0, 98.15, 98.16, 98.14, 98.08, 98.26, 98.03, 98.12, 98.27, 98.23, 97.66, 97.99, 98.3, 98.3, 97.57, 98.12, 98.3, 97.99, 98.18, 98.2, 98.46, 97.87, 98.22, 98.41, 98.35, 98.2, 98.41, 98.26, 98.38, 98.38, 98.01, 98.28, 97.94, 98.34, 97.89, 98.36, 97.64, 97.75, 98.02, 97.83, 98.23, 97.92, 98.01, 97.75, 98.1, 98.04, 97.95, 97.91, 98.16, 98.08, 98.32, 98.08, 97.98, 97.93, 98.29, 98.04, 98.12, 98.01, 97.51, 97.73, 97.38, 98.1, 97.68, 97.94, 97.34, 97.41, 97.16, 97.41, 97.99, 97.84, 97.22, 97.2, 97.36, 97.09, 96.22, 97.58, 97.35, 97.53, 96.87, 96.6, 96.79, 95.94, 97.15, 96.03, 96.53, 95.04, 96.61, 96.16, 94.7, 95.79, 95.3, 95.61, 95.96, 94.12, 95.22, 93.64, 95.57, 94.63, 93.4, 94.26, 93.01, 94.28, 91.38, 94.36, 92.04, 94.06, 90.31, 91.75, 94.25, 90.23, 91.06, 92.66, 91.2, 90.39, 91.13, 90.64, 87.24, 92.84, 90.48, 91.84, 89.44, 89.28, 86.19, 84.68, 87.25, 86.99, 85.98, 86.62, 87.23, 83.16, 83.04, 86.11, 83.75, 82.44, 82.76, 83.71, 82.26, 77.33, 77.99, 79.99, 79.41, 74.85, 77.81, 78.38, 76.03, 77.88, 78.38, 76.16, 71.48, 73.25, 77.35, 70.46, 71.15, 74.51, 76.89, 74.25, 74.63, 74.53, 70.87, 73.43, 73.49, 72.21, 71.75, 72.5, 73.13, 68.15, 70.63, 76.26, 74.6, 71.23, 74.51, 76.37, 73.81, 73.64, 76.06, 75.13, 70.88, 72.79, 73.35, 72.34, 73.08, 75.0, 72.44, 70.41, 72.6, 70.2, 70.46, 72.8, 72.87, 72.3, 72.37, 75.55, 73.21, 72.21, 70.92, 70.46, 72.62, 69.68, 72.16, 70.7, 70.73, 74.93, 74.73, 71.1, 74.28, 71.11, 74.25, 69.27, 70.5, 73.28, 71.23, 69.14, 75.19, 75.16, 70.66, 71.42, 75.35, 72.85, 72.26, 75.4, 76.62, 70.97, 75.24, 72.59, 74.65, 73.61, 72.66, 73.51, 64.66, 71.79, 71.95, 68.17, 74.59, 74.85, 74.0, 71.36, 77.63, 72.53, 72.97, 75.04, 74.91, 72.38, 68.88, 72.3, 68.73, 65.91, 60.86, 64.18, 64.88, 64.62, 73.99, 53.13, 58.64, 48.81, 51.2, 55.1, 55.13, 56.94, 52.03, 52.48, 42.65, 49.6, 37.71, 35.95, 34.62, 34.98, 37.53, 38.83, 26.13, 28.75, 24.1, 35.7, 25.51, 37.62, 30.21, 20.72, 36.08, 36.51, 35.67, 30.19, 36.31, 27.73, 33.56, 33.27, 29.33, 27.81, 26.73, 27.45, 25.75, 27.79, 27.22, 28.97, 25.23, 34.44, 27.58, 26.44, 28.32, 27.85, 27.48, 24.1, 27.24, 29.1, 30.2, 31.86, 34.5, 42.57, 30.04, 34.06, 31.5, 31.02, 29.52, 43.59, 45.82, 37.65, 28.36, 32.74, 34.37, 36.64, 30.02, 36.42, 36.66, 33.86, 35.13, 40.53, 40.73, 35.16, 31.44, 33.82, 33.47, 33.47, 30.25, 34.78, 31.59, 30.17, 40.57, 36.52, 29.33, 35.61, 30.67, 38.24, 31.02, 29.44, 28.11, 28.53, 35.34, 35.52, 30.61, 30.99, 27.94, 38.12, 34.55, 34.14, 28.77, 31.49, 35.93, 27.08, 31.6, 34.73, 29.58, 28.62, 26.5, 28.96, 27.83, 31.39, 29.43, 31.27, 34.26, 31.38, 31.9, 29.61, 35.75, 31.16, 31.64, 37.41, 35.96, 35.0, 38.31, 44.54, 35.95, 47.47, 47.69, 57.67, 59.74, 56.18, 56.7, 47.06, 49.6, 47.85, 42.61, 45.43, 38.17, 40.03, 42.23, 43.47, 34.16, 33.28, 38.72, 32.64, 30.26, 34.92, 31.42, 38.05, 29.5, 29.24, 33.83, 30.29, 37.54, 31.31, 34.69, 29.67, 33.03, 32.04, 37.8, 32.91, 33.04, 34.63, 29.99, 35.24, 30.04, 39.8, 35.95, 37.16, 41.05, 32.61, 39.84, 45.56, 34.06, 35.84, 42.41, 38.93, 40.12, 38.85, 47.14, 41.79, 40.32, 44.09, 47.05, 57.05, 46.89, 39.19]
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null
Component of an E-cadherin/ catenin adhesion complex composed of at least E-cadherin/CDH1, beta-catenin/CTNNB1 or gamma-catenin/JUP, and potentially alpha-catenin/CTNNA1. Forms a ternary complex composed of ADAM10, CADH1 and EPHA4,
null
null
KLRG1, SPEF1, DLGAP5, AJAP1, RAPGEF2, RAB8B, PIP5K1C, PKP2, TRPV4, CTNNB1, CAV1, DDR1, TBC1D2, CTNNA1, JUP, CTNND1, PSEN1, LIMA1, CDH1, JUP, ADAM10, CADH1 , EPHA4,
null
null
null
null
Homodimer
null
79.91949
0.474025
73.293166
0.627275
1,115
P12830
Q86T82
null
degron_data
CDH1
MGPWSRSLSALLLLLQVSSWLCQEPEPCHPGFDAESYTFTVPRRHLERGRVLGRVNFEDCTGRQRTAYFSLDTRFKVGTDGVITVKRPLRFHNPQIHFLVYAWDSTYRKFSTKVTLNTVGHHHRPPPHQASVSGIQAELLTFPNSSPGLRRQKRDWVIPPISCPENEKGPFPKNLVQIKSNKDKEGKVFYSITGQGADTPPVGVFIIERETGWLKVTEPLDRERIATYTLFSHAVSSNGNAVEDPMEILITVTDQNDNKPEFTQEVFKGSVMEGALPGTSVMEVTATDADDDVNTYNAAIAYTILSQDPELPDKNMFTINRNTGVISVVTTGLDRESFPTYTLVVQAADLQGEGLSTTATAVITVTDTNDNPPIFNPTTYKGQVPENEANVVITTLKVTDADAPNTPAWEAVYTILNDDGGQFVVTTNPVNNDGILKTAKGLDFEAKQQYILHVAVTNVVPFEVSLTTSTATVTVDVLDVNEAPIFVPPEKRVEVSEDFGVGQEITSYTAQEPDTFMEQKITYRIWRDTANWLEINPDTGAISTRAELDREDFEHVKNSTYTALIIATDNGSPVATGTGTLLLILSDVNDNAPIPEPRTIFFCERNPKPQVINIIDADLPPNTSPFTAELTHGASANWTIQYNDPTQESIILKPKMALEVGDYKINLKLMDNQNKDQVTTLEVSVCDCEGAAGVCRKAQPVEAGLQIPAILGILGGILALLILILLLLLFLRRRAVVKEPLLPPEDDTRDNVYYYDEEGGGEEDQDFDLSQLHRGLDARPEVTRNDVAPTLMSVPRYLPRPANPDEIGNFIDENLKAADTDPTAPPYDSLLVFDYEGSGSEAASLSSLNSSESDKDQDYDYLNEWGNRFKKLADMYGGGEDD
Homo sapiens
Cell junction, adherens junction, Cell membrane, Endosome, Golgi apparatus, trans-Golgi network, Cytoplasm, Cell junction, desmosome
Tissue enhanced (parathyroid)
{'Ciliated cells': '119.1', 'Basal respiratory cells': '71.1', 'Club cells': '97.3', 'Ionocytes': '81.0', 'Mucus glandular cells': '155.0', 'Serous glandular cells': '67.8', 'Gastric mucus-secreting cells': '133.2', 'Proximal enterocytes': '140.9', 'Paneth cells': '125.1', 'Distal enterocytes': '307.5', 'Intestinal goblet cells': '173.5', 'Exocrine glandular cells': '-0.605', 'Basal prostatic cells': '68.3', 'Prostatic glandular cells': '186.7', 'Breast glandular cells': '0.773', 'Breast myoepithelial cells': '0.700', 'Glandular and luminal cells': '313.0', 'Secretory cells': '82.3', 'Basal keratinocytes': '102.5', 'Suprabasal keratinocytes': '162.6', 'Basal squamous epithelial cells': '51.0', 'Squamous epithelial cells': '106.9', 'Alveolar cells type 1': '0.437', 'Alveolar cells type 2': '0.706', 'Salivary duct cells': '95.9', 'Ductal cells': '0.541', 'Hepatocytes': '0.600', 'Cholangiocytes': '129.7', 'Proximal tubular cells': '0.042', 'Distal tubular cells': '0.0', 'Collecting duct cells': '143.9', 'Mesothelial cells': '0.799', 'Sertoli cells': '0.252', 'Granulosa cells': '12.9', 'Enteroendocrine cells': '92.4', 'Pancreatic endocrine cells': '78.1', 'Leydig cells': '0.264', 'Excitatory neurons': '0.7', 'Inhibitory neurons': '1.3', 'Cone photoreceptor cells': '0.0', 'Rod photoreceptor cells': '0.0', 'Bipolar cells': '0.2', 'Horizontal cells': '0.6', 'Astrocytes': '0.6', 'Oligodendrocyte precursor cells': '0.5', 'Oligodendrocytes': '29.9', 'Microglial cells': '0.9', 'Muller glia cells': '0.1', 'Schwann cells': '0.131', 'Spermatogonia': '0.392', 'Spermatocytes': '0.193', 'Early spermatids': '-0.217', 'Late spermatids': '-0.290', 'Oocytes': '16.9', 'Cytotrophoblasts': '119.2', 'Syncytiotrophoblasts': '45.0', 'Extravillous trophoblasts': '24.9', 'Endothelial cells': '6.1', 'Lymphatic endothelial cells': '0.4', 'Cardiomyocytes': '0.135', 'Skeletal myocytes': '0.107', 'Smooth muscle cells': '5.8', 'Adipocytes': '2.1', 'Melanocytes': '0.335', 'Fibroblasts': '6.5', 'Peritubular cells': '0.210', 'Endometrial stromal cells': '27.7', 'Ovarian stromal cells': '0.7', 'Undifferentiated cells': '101.6', 'T-cells': '2.9', 'B-cells': '4.4', 'Plasma cells': '6.1', 'Nk-cells': '0.0', 'Granulocytes': '8.4', 'Monocytes': '0.0', 'Macrophages': '6.0', 'Hofbauer cells': '4.3', 'Kupffer cells': '1.0', 'Dendritic cells': '5.9', 'Langerhans cells': '0.304', 'Erythroid cells': '0.036', 'Adipocytes (Subcutaneous)': '-0.081', 'Adipocytes (Visceral)': '-0.209', 'Breast glandular cells (progenitors)': '0.538', 'Adipocytes (Breast)': '-0.689', 'Colon enterocytes': '0.790', 'Colon enteroendocrine cells': '0.112', 'Enteric glia cells': '-0.048', 'Mitotic cells (Colon)': '0.299', 'Mitotic cells (Heart)': '0.120', 'Podocytes': '-0.118', 'Ascending Loop of Henle cells': '0.475', 'Intercalated cells': '0.212', 'Cholangiocyte': '0.090', 'NK-cells (Liver)': '-0.005', 'Respiratory ciliated cells': '-0.012', 'Mitotic cells (Lung)': '0.071', 'NK-cells (Lung)': '-0.266', 'B-cells (Lung)': '-0.296', 'Alpha cells': '0.270', 'Beta cells': '0.152', 'Prostate glandular cells': '0.764', 'Prostate basal glandular cells': '0.540', 'Urothelial cells': '0.205', 'Keratinocyte (other)': '0.510', 'Keratinocyte (granular)': '0.055', 'Hair cortex cells': '0.080', 'Inner root sheath cells': '0.131', 'Outer root sheath cells': '0.175', 'Sebaceous gland cells': '0.156', 'Eccrine sweat gland cells': '-0.207', 'Adipocytes (Skin)': '-0.244', 'Mitotic cells (Skin)': '0.442', 'Parietal cells': '0.654', 'Chief cells': '0.649', 'Gastric mucous cells': '0.781', 'Gastric enteroendocrine cells': '0.590', 'Mitotic cells (Stomach)': '0.445', 'Parafollicular cells': '0.173', 'Thyroid glandular cells': '0.865', 'Mitotic cells (Thyroid)': '-0.081', 'Adrenal cortex cells': '0.051', 'Adrenal medulla cells': '0.087', 'Mitotic cells (Adrenal gland)': '0.072', 'Minor salivary glandular cells': '0.371', 'Minor salivary gland ductal cells': '-0.142', 'Minor salivary gland basal cells': '0.582', 'Mitotic cells (Minor salivary gland)': '0.567', 'Adipocytes (Minor salivary gland)': '0.050', 'Somatotropes': '0.121', 'Lactotropes': '0.322', 'Gonadotropes': '0.330', 'Corticotropes': '0.180', 'Thyrotropes': '0.496', 'Undifferentiated cells (Pituitary gland)': '-0.108', 'Mitotic cells (Spleen)': '-0.228', 'Platelets': '-0.050', 'Erythrocytes': '-0.158', 'Hematopoietic stem cells': '-0.211', 'B-cells (Spleen)': '0.266', 'NK-cells (Spleen)': '0.309', 'Amygdala excitatory': '1.0', 'Cerebellar inhibitory': '0.9', 'Cge interneuron': '0.7', 'Deep-layer corticothalamic and 6b': '1.5', 'Deep-layer intratelencephalic': '0.7', 'Deep-layer near-projecting': '0.7', 'Eccentric medium spiny neuron': '0.6', 'Hippocampal ca1-3': '1.9', 'Hippocampal ca4': '1.2', 'Hippocampal dentate gyrus': '1.1', 'Lamp5-lhx6 and chandelier': '0.5', 'Lower rhombic lip': '0.8', 'Mammillary body': '0.6', 'Medium spiny neuron': '0.7', 'Mge interneuron': '1.7', 'Midbrain-derived inhibitory': '0.7', 'Miscellaneous': '0.9', 'Splatter': '3.8', 'Thalamic excitatory': '0.5', 'Upper rhombic lip': '0.8', 'Upper-layer intratelencephalic': '0.6', 'Astrocyte': '4.4', 'Bergmann glia': '0.2', 'Central nervous system macrophage': '0.6', 'Choroid plexus epithelial cell': '52.1', 'Committed oligodendrocyte precursor': '41.5', 'Ependymal cell': '4.8', 'Oligodendrocyte': '53.1', 'Oligodendrocyte precursor cell': '2.4', 'Endothelial cell': '0.7', 'Pericyte': '0.3', 'Vascular associated smooth muscle cell': '0.0', 'Fibroblast': '17.4', 'Leukocyte': '1.1', 'Basophil': '0.0', 'Eosinophil': '0.0', 'Neutrophil': '0.0', 'Classical monocyte': '0.0', 'Non-classical monocyte': '0.0', 'Intermediate monocyte': '0.0', 'T-reg': '2.3', 'GdT-cell': '0.0', 'MAIT T-cell': '0.0', 'Memory CD4 T-cell': '0.0', 'Naive CD4 T-cell': '0.1', 'Memory CD8 T-cell': '0.2', 'Naive CD8 T-cell': '0.3', 'Memory B-cell': '0.0', 'Naive B-cell': '0.1', 'Plasmacytoid DC': '46.6', 'Myeloid DC': '8.5', 'NK-cell': '0.1', 'Total PBMC': '0.7', 'Vd2 gdTCR': '0.0', 'Memory CD4 T-cell Th1\\/Th17': '0.1', 'Memory CD4 T-cell Th17': '0.2', 'Memory CD4 T-cell Th2': '2.9', 'Non-Vd2 gdTCR': '0.1', 'Memory CD4 T-cell Th1': '0.3', 'Memory CD4 T-cell TFH': '0.5', 'Terminal effector memory CD4 T-cell': '0.0', 'Central memory CD8 T-cell': '4.8', 'Effector memory CD8 T-cell': '0.0', 'Terminal effector memory CD8 T-cell': '0.6', 'Non-switched memory B-cell': '0.0', 'Plasmablast': '3.3', 'Switched memory B-cell': '0.0', 'Exhausted memory B-cell': '0.7', 'Progenitor cell': '2.3', 'Memory T-reg': '1.3', 'Naive CD4 T-cell activated': '0.3', 'Naive CD8 T-cell activated': '0.6', 'Naive T-reg': '0.1'}
1O6S, 2O72, 2OMT, 2OMU, 2OMV, 2OMX, 2OMY, 2OMZ, 3FF7, 3FF8, 3L6X, 3L6Y, 4ZT1, 4ZTE, 6CXY, 6OLE, 6OLF, 6OLG, 6VEL, 7STZ, 8H62
{'Adipose Tissue': 1.2125261088039867, 'Adrenal Gland': 0.1914223992248062, 'Bladder': 39.2033519047619, 'Blood': 1.340954264800861, 'Blood Vessel': 0.3121561692883895, 'Brain': 0.8550442199091597, 'Breast': 38.54918344226579, 'Cervix Uteri': 23.539115789473684, 'Colon': 43.41292142490372, 'Esophagus': 53.97513367404844, 'Fallopian Tube': 14.900277777777776, 'Heart': 0.119140469221835, 'Kidney': 25.040449438202245, 'Liver': 26.60802654867257, 'Lung': 35.447986366782004, 'Muscle': 0.1378936151930261, 'Nerve': 17.518468982229404, 'Ovary': 3.6515122222222223, 'Pancreas': 56.89676829268293, 'Pituitary': 24.68741660777385, 'Prostate': 61.279967346938776, 'Salivary Gland': 92.01685185185184, 'Skin': 79.77571720232172, 'Small Intestine': 71.7519320855615, 'Spleen': 10.061029045643156, 'Stomach': 58.07813805013927, 'Testis': 0.8144204986149585, 'Thyroid': 135.176797856049, 'Uterus': 1.442593943661972, 'Vagina': 86.52345512820513}
USP37
MSPLKIHGPIRIRSMQTGITKWKEGSFEIVEKENKVSLVVHYNTGGIPRIFQLSHNIKNVVLRPSGAKQSRLMLTLQDNSFLSIDKVPSKDAEEMRLFLDAVHQNRLPAAMKPSQGSGSFGAILGSRTSQKETSRQLSYSDNQASAKRGSLETKDDIPFRKVLGNPGRGSIKTVAGSGIARTIPSLTSTSTPLRSGLLENRTEKRKRMISTGSELNEDYPKENDSSSNNKAMTDPSRKYLTSSREKQLSLKQSEENRTSGLLPLQSSSFYGSRAGSKEHSSGGTNLDRTNVSSQTPSAKRSLGFLPQPVPLSVKKLRCNQDYTGWNKPRVPLSSHQQQQLQGFSNLGNTCYMNAILQSLFSLQSFANDLLKQGIPWKKIPLNALIRRFAHLLVKKDICNSETKKDLLKKVKNAISATAERFSGYMQNDAHEFLSQCLDQLKEDMEKLNKTWKTEPVSGEENSPDISATRAYTCPVITNLEFEVQHSIICKACGEIIPKREQFNDLSIDLPRRKKPLPPRSIQDSLDLFFRAEELEYSCEKCGGKCALVRHKFNRLPRVLILHLKRYSFNVALSLNNKIGQQVIIPRYLTLSSHCTENTKPPFTLGWSAHMAISRPLKASQMVNSCITSPSTPSKKFTFKSKSSLALCLDSDSEDELKRSVALSQRLCEMLGNEQQQEDLEKDSKLCPIEPDKSELENSGFDRMSEEELLAAVLEISKRDASPSLSHEDDDKPTSSPDTGFAEDDIQEMPENPDTMETEKPKTITELDPASFTEITKDCDENKENKTPEGSQGEVDWLQQYDMEREREEQELQQALAQSLQEQEAWEQKEDDDLKRATELSLQEFNNSFVDALGSDEDSGNEDVFDMEYTEAEAEELKRNAETGNLPHSYRLISVVSHIGSTSSSGHYISDVYDIKKQAWFTYNDLEVSKIQEAAVQSDRDRSGYIFFYMHKEIFDELLETEKNSQSLSTEVGKTTRQAL
Homo sapiens
Nucleus, Chromosome
Low tissue specificity
{'Ciliated cells': '11.3', 'Basal respiratory cells': '7.5', 'Club cells': '9.7', 'Ionocytes': '9.2', 'Mucus glandular cells': '18.6', 'Serous glandular cells': '5.2', 'Gastric mucus-secreting cells': '7.1', 'Proximal enterocytes': '6.1', 'Paneth cells': '8.2', 'Distal enterocytes': '5.5', 'Intestinal goblet cells': '7.8', 'Exocrine glandular cells': '-0.559', 'Basal prostatic cells': '11.4', 'Prostatic glandular cells': '12.8', 'Breast glandular cells': '0.449', 'Breast myoepithelial cells': '0.553', 'Glandular and luminal cells': '15.8', 'Secretory cells': '9.3', 'Basal keratinocytes': '15.2', 'Suprabasal keratinocytes': '16.2', 'Basal squamous epithelial cells': '18.6', 'Squamous epithelial cells': '12.2', 'Alveolar cells type 1': '0.186', 'Alveolar cells type 2': '-0.079', 'Salivary duct cells': '15.6', 'Ductal cells': '0.560', 'Hepatocytes': '0.452', 'Cholangiocytes': '0.0', 'Proximal tubular cells': '0.210', 'Distal tubular cells': '0.0', 'Collecting duct cells': '5.8', 'Mesothelial cells': '0.253', 'Sertoli cells': '-0.228', 'Granulosa cells': '19.2', 'Enteroendocrine cells': '8.2', 'Pancreatic endocrine cells': '8.5', 'Leydig cells': '-0.300', 'Excitatory neurons': '45.8', 'Inhibitory neurons': '38.4', 'Cone photoreceptor cells': '6.8', 'Rod photoreceptor cells': '20.2', 'Bipolar cells': '8.9', 'Horizontal cells': '22.0', 'Astrocytes': '32.5', 'Oligodendrocyte precursor cells': '33.0', 'Oligodendrocytes': '56.3', 'Microglial cells': '25.9', 'Muller glia cells': '8.6', 'Schwann cells': '0.092', 'Spermatogonia': '0.113', 'Spermatocytes': '0.495', 'Early spermatids': '0.494', 'Late spermatids': '0.415', 'Oocytes': '33.1', 'Cytotrophoblasts': '8.5', 'Syncytiotrophoblasts': '7.1', 'Extravillous trophoblasts': '7.1', 'Endothelial cells': '12.2', 'Lymphatic endothelial cells': '9.2', 'Cardiomyocytes': '0.569', 'Skeletal myocytes': '0.036', 'Smooth muscle cells': '18.6', 'Adipocytes': '12.8', 'Melanocytes': '0.245', 'Fibroblasts': '11.0', 'Peritubular cells': '-0.203', 'Endometrial stromal cells': '11.2', 'Ovarian stromal cells': '12.3', 'Undifferentiated cells': '9.0', 'T-cells': '17.7', 'B-cells': '15.8', 'Plasma cells': '11.4', 'Nk-cells': '14.6', 'Granulocytes': '15.4', 'Monocytes': '13.0', 'Macrophages': '19.6', 'Hofbauer cells': '7.6', 'Kupffer cells': '7.5', 'Dendritic cells': '12.8', 'Langerhans cells': '0.254', 'Erythroid cells': '-0.066', 'Adipocytes (Subcutaneous)': '-0.404', 'Adipocytes (Visceral)': '-0.344', 'Breast glandular cells (progenitors)': '0.337', 'Adipocytes (Breast)': '-0.499', 'Colon enterocytes': '0.002', 'Colon enteroendocrine cells': '0.224', 'Enteric glia cells': '-0.191', 'Mitotic cells (Colon)': '0.123', 'Mitotic cells (Heart)': '0.471', 'Podocytes': '-0.048', 'Ascending Loop of Henle cells': '0.371', 'Intercalated cells': '0.049', 'Cholangiocyte': '0.287', 'NK-cells (Liver)': '-0.328', 'Respiratory ciliated cells': '0.055', 'Mitotic cells (Lung)': '-0.038', 'NK-cells (Lung)': '0.241', 'B-cells (Lung)': '0.102', 'Alpha cells': '0.312', 'Beta cells': '0.165', 'Prostate glandular cells': '-0.085', 'Prostate basal glandular cells': '0.223', 'Urothelial cells': '0.174', 'Keratinocyte (other)': '0.361', 'Keratinocyte (granular)': '-0.067', 'Hair cortex cells': '-0.038', 'Inner root sheath cells': '0.016', 'Outer root sheath cells': '0.142', 'Sebaceous gland cells': '0.057', 'Eccrine sweat gland cells': '0.023', 'Adipocytes (Skin)': '-0.175', 'Mitotic cells (Skin)': '0.388', 'Parietal cells': '-0.522', 'Chief cells': '-0.465', 'Gastric mucous cells': '-0.313', 'Gastric enteroendocrine cells': '-0.311', 'Mitotic cells (Stomach)': '0.043', 'Parafollicular cells': '0.052', 'Thyroid glandular cells': '0.288', 'Mitotic cells (Thyroid)': '0.053', 'Adrenal cortex cells': '0.348', 'Adrenal medulla cells': '0.047', 'Mitotic cells (Adrenal gland)': '0.160', 'Minor salivary glandular cells': '0.413', 'Minor salivary gland ductal cells': '0.247', 'Minor salivary gland basal cells': '0.291', 'Mitotic cells (Minor salivary gland)': '0.234', 'Adipocytes (Minor salivary gland)': '0.133', 'Somatotropes': '-0.052', 'Lactotropes': '0.043', 'Gonadotropes': '0.116', 'Corticotropes': '-0.121', 'Thyrotropes': '0.060', 'Undifferentiated cells (Pituitary gland)': '0.018', 'Mitotic cells (Spleen)': '0.074', 'Platelets': '-0.129', 'Erythrocytes': '-0.068', 'Hematopoietic stem cells': '-0.206', 'B-cells (Spleen)': '0.213', 'NK-cells (Spleen)': '0.198', 'Amygdala excitatory': '77.8', 'Cerebellar inhibitory': '58.2', 'Cge interneuron': '54.8', 'Deep-layer corticothalamic and 6b': '70.5', 'Deep-layer intratelencephalic': '68.9', 'Deep-layer near-projecting': '58.8', 'Eccentric medium spiny neuron': '79.1', 'Hippocampal ca1-3': '64.5', 'Hippocampal ca4': '61.1', 'Hippocampal dentate gyrus': '71.6', 'Lamp5-lhx6 and chandelier': '51.3', 'Lower rhombic lip': '49.4', 'Mammillary body': '61.2', 'Medium spiny neuron': '108.0', 'Mge interneuron': '54.2', 'Midbrain-derived inhibitory': '58.3', 'Miscellaneous': '62.9', 'Splatter': '56.4', 'Thalamic excitatory': '52.7', 'Upper rhombic lip': '79.8', 'Upper-layer intratelencephalic': '70.5', 'Astrocyte': '70.9', 'Bergmann glia': '67.0', 'Central nervous system macrophage': '101.1', 'Choroid plexus epithelial cell': '52.2', 'Committed oligodendrocyte precursor': '55.1', 'Ependymal cell': '59.8', 'Oligodendrocyte': '94.5', 'Oligodendrocyte precursor cell': '59.9', 'Endothelial cell': '79.6', 'Pericyte': '67.8', 'Vascular associated smooth muscle cell': '95.5', 'Fibroblast': '75.4', 'Leukocyte': '80.5', 'Basophil': '23.7', 'Eosinophil': '3.8', 'Neutrophil': '10.4', 'Classical monocyte': '4.6', 'Non-classical monocyte': '10.3', 'Intermediate monocyte': '14.1', 'T-reg': '24.3', 'GdT-cell': '3.1', 'MAIT T-cell': '27.5', 'Memory CD4 T-cell': '2.6', 'Naive CD4 T-cell': '18.7', 'Memory CD8 T-cell': '2.7', 'Naive CD8 T-cell': '14.6', 'Memory B-cell': '2.5', 'Naive B-cell': '19.4', 'Plasmacytoid DC': '11.0', 'Myeloid DC': '10.7', 'NK-cell': '14.1', 'Total PBMC': '12.2', 'Vd2 gdTCR': '22.4', 'Memory CD4 T-cell TFH': '13.0', 'Memory CD4 T-cell Th2': '15.9', 'Memory CD4 T-cell Th17': '13.9', 'Memory CD4 T-cell Th1\\/Th17': '15.0', 'Non-Vd2 gdTCR': '22.0', 'Memory CD4 T-cell Th1': '13.8', 'Terminal effector memory CD4 T-cell': '29.7', 'Central memory CD8 T-cell': '23.2', 'Effector memory CD8 T-cell': '20.2', 'Terminal effector memory CD8 T-cell': '21.2', 'Switched memory B-cell': '20.3', 'Plasmablast': '11.7', 'Non-switched memory B-cell': '20.7', 'Exhausted memory B-cell': '18.9', 'Progenitor cell': '16.9', 'Memory T-reg': '12.4', 'Naive CD4 T-cell activated': '33.4', 'Naive CD8 T-cell activated': '27.2', 'Naive T-reg': '17.6'}
3U12
{'Adipose Tissue': 3.21072084717608, 'Adrenal Gland': 2.0273151162790697, 'Bladder': 2.9935047619047617, 'Blood': 2.6654355543595263, 'Blood Vessel': 3.063154531835206, 'Brain': 1.175899799394398, 'Breast': 3.1753529411764707, 'Cervix Uteri': 3.4515263157894736, 'Colon': 2.0876043645699616, 'Esophagus': 2.071504775086505, 'Fallopian Tube': 2.9771111111111113, 'Heart': 0.8953271544715447, 'Kidney': 0.9994820224719102, 'Liver': 1.0181522123893805, 'Lung': 3.051868685121107, 'Muscle': 1.5923395890410958, 'Nerve': 3.8501457189014543, 'Ovary': 5.947299999999999, 'Pancreas': 0.9775213414634146, 'Pituitary': 1.970709187279152, 'Prostate': 2.2869044897959183, 'Salivary Gland': 2.857125925925926, 'Skin': 3.5872116639027087, 'Small Intestine': 2.6666245989304813, 'Spleen': 1.6605701244813278, 'Stomach': 1.636486044568245, 'Testis': 13.727795013850416, 'Thyroid': 2.9686462480857583, 'Uterus': 3.360823943661972, 'Vagina': 3.385294871794872}
[39.93, 46.46, 52.9, 44.21, 41.4, 39.93, 35.91, 38.61, 36.44, 36.25, 34.86, 32.82, 32.01, 32.75, 31.69, 35.64, 36.35, 34.66, 33.32, 32.71, 35.01, 30.17, 37.05, 36.53, 48.19, 58.22, 64.94, 73.22, 78.33, 82.63, 85.79, 89.39, 87.89, 85.58, 83.93, 89.1, 89.27, 90.66, 87.86, 86.2, 82.97, 72.75, 73.3, 76.44, 82.38, 82.41, 79.49, 86.6, 76.32, 85.48, 88.69, 84.35, 87.75, 90.57, 88.72, 89.46, 87.48, 85.3, 81.72, 79.46, 77.26, 69.01, 67.1, 62.83, 67.71, 74.96, 82.95, 86.74, 86.35, 86.49, 84.6, 85.99, 85.64, 87.19, 89.23, 89.3, 90.62, 84.21, 85.42, 83.34, 84.28, 89.8, 89.78, 87.53, 87.64, 85.98, 81.31, 80.85, 78.74, 80.15, 70.67, 69.91, 72.91, 77.13, 83.26, 84.67, 90.36, 89.7, 92.74, 89.99, 92.55, 88.84, 87.15, 83.78, 78.78, 81.48, 78.75, 84.94, 88.04, 89.37, 92.07, 91.77, 92.31, 91.07, 90.65, 87.61, 83.41, 78.8, 63.24, 54.89, 47.42, 40.03, 40.26, 30.18, 41.24, 38.09, 36.95, 39.02, 37.83, 36.36, 36.19, 34.8, 36.01, 35.89, 38.28, 40.63, 35.0, 43.8, 39.75, 41.2, 46.04, 45.19, 52.52, 50.11, 47.93, 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null
Component of an E-cadherin/ catenin adhesion complex composed of at least E-cadherin/CDH1, beta-catenin/CTNNB1 or gamma-catenin/JUP, and potentially alpha-catenin/CTNNA1. Forms a ternary complex composed of ADAM10, CADH1 and EPHA4,
null
null
KLRG1, SPEF1, DLGAP5, AJAP1, RAPGEF2, RAB8B, PIP5K1C, PKP2, TRPV4, CTNNB1, CAV1, DDR1, TBC1D2, CTNNA1, JUP, CTNND1, PSEN1, LIMA1, CDH1, JUP, ADAM10, CADH1 , EPHA4,
null
null
null
null
Homodimer
null
79.91949
0.474025
63.181614
0.5857
532
P12830
Q86WB0
null
degron_data
CDH1
MGPWSRSLSALLLLLQVSSWLCQEPEPCHPGFDAESYTFTVPRRHLERGRVLGRVNFEDCTGRQRTAYFSLDTRFKVGTDGVITVKRPLRFHNPQIHFLVYAWDSTYRKFSTKVTLNTVGHHHRPPPHQASVSGIQAELLTFPNSSPGLRRQKRDWVIPPISCPENEKGPFPKNLVQIKSNKDKEGKVFYSITGQGADTPPVGVFIIERETGWLKVTEPLDRERIATYTLFSHAVSSNGNAVEDPMEILITVTDQNDNKPEFTQEVFKGSVMEGALPGTSVMEVTATDADDDVNTYNAAIAYTILSQDPELPDKNMFTINRNTGVISVVTTGLDRESFPTYTLVVQAADLQGEGLSTTATAVITVTDTNDNPPIFNPTTYKGQVPENEANVVITTLKVTDADAPNTPAWEAVYTILNDDGGQFVVTTNPVNNDGILKTAKGLDFEAKQQYILHVAVTNVVPFEVSLTTSTATVTVDVLDVNEAPIFVPPEKRVEVSEDFGVGQEITSYTAQEPDTFMEQKITYRIWRDTANWLEINPDTGAISTRAELDREDFEHVKNSTYTALIIATDNGSPVATGTGTLLLILSDVNDNAPIPEPRTIFFCERNPKPQVINIIDADLPPNTSPFTAELTHGASANWTIQYNDPTQESIILKPKMALEVGDYKINLKLMDNQNKDQVTTLEVSVCDCEGAAGVCRKAQPVEAGLQIPAILGILGGILALLILILLLLLFLRRRAVVKEPLLPPEDDTRDNVYYYDEEGGGEEDQDFDLSQLHRGLDARPEVTRNDVAPTLMSVPRYLPRPANPDEIGNFIDENLKAADTDPTAPPYDSLLVFDYEGSGSEAASLSSLNSSESDKDQDYDYLNEWGNRFKKLADMYGGGEDD
Homo sapiens
Cell junction, adherens junction, Cell membrane, Endosome, Golgi apparatus, trans-Golgi network, Cytoplasm, Cell junction, desmosome
Tissue enhanced (parathyroid)
{'Ciliated cells': '119.1', 'Basal respiratory cells': '71.1', 'Club cells': '97.3', 'Ionocytes': '81.0', 'Mucus glandular cells': '155.0', 'Serous glandular cells': '67.8', 'Gastric mucus-secreting cells': '133.2', 'Proximal enterocytes': '140.9', 'Paneth cells': '125.1', 'Distal enterocytes': '307.5', 'Intestinal goblet cells': '173.5', 'Exocrine glandular cells': '-0.605', 'Basal prostatic cells': '68.3', 'Prostatic glandular cells': '186.7', 'Breast glandular cells': '0.773', 'Breast myoepithelial cells': '0.700', 'Glandular and luminal cells': '313.0', 'Secretory cells': '82.3', 'Basal keratinocytes': '102.5', 'Suprabasal keratinocytes': '162.6', 'Basal squamous epithelial cells': '51.0', 'Squamous epithelial cells': '106.9', 'Alveolar cells type 1': '0.437', 'Alveolar cells type 2': '0.706', 'Salivary duct cells': '95.9', 'Ductal cells': '0.541', 'Hepatocytes': '0.600', 'Cholangiocytes': '129.7', 'Proximal tubular cells': '0.042', 'Distal tubular cells': '0.0', 'Collecting duct cells': '143.9', 'Mesothelial cells': '0.799', 'Sertoli cells': '0.252', 'Granulosa cells': '12.9', 'Enteroendocrine cells': '92.4', 'Pancreatic endocrine cells': '78.1', 'Leydig cells': '0.264', 'Excitatory neurons': '0.7', 'Inhibitory neurons': '1.3', 'Cone photoreceptor cells': '0.0', 'Rod photoreceptor cells': '0.0', 'Bipolar cells': '0.2', 'Horizontal cells': '0.6', 'Astrocytes': '0.6', 'Oligodendrocyte precursor cells': '0.5', 'Oligodendrocytes': '29.9', 'Microglial cells': '0.9', 'Muller glia cells': '0.1', 'Schwann cells': '0.131', 'Spermatogonia': '0.392', 'Spermatocytes': '0.193', 'Early spermatids': '-0.217', 'Late spermatids': '-0.290', 'Oocytes': '16.9', 'Cytotrophoblasts': '119.2', 'Syncytiotrophoblasts': '45.0', 'Extravillous trophoblasts': '24.9', 'Endothelial cells': '6.1', 'Lymphatic endothelial cells': '0.4', 'Cardiomyocytes': '0.135', 'Skeletal myocytes': '0.107', 'Smooth muscle cells': '5.8', 'Adipocytes': '2.1', 'Melanocytes': '0.335', 'Fibroblasts': '6.5', 'Peritubular cells': '0.210', 'Endometrial stromal cells': '27.7', 'Ovarian stromal cells': '0.7', 'Undifferentiated cells': '101.6', 'T-cells': '2.9', 'B-cells': '4.4', 'Plasma cells': '6.1', 'Nk-cells': '0.0', 'Granulocytes': '8.4', 'Monocytes': '0.0', 'Macrophages': '6.0', 'Hofbauer cells': '4.3', 'Kupffer cells': '1.0', 'Dendritic cells': '5.9', 'Langerhans cells': '0.304', 'Erythroid cells': '0.036', 'Adipocytes (Subcutaneous)': '-0.081', 'Adipocytes (Visceral)': '-0.209', 'Breast glandular cells (progenitors)': '0.538', 'Adipocytes (Breast)': '-0.689', 'Colon enterocytes': '0.790', 'Colon enteroendocrine cells': '0.112', 'Enteric glia cells': '-0.048', 'Mitotic cells (Colon)': '0.299', 'Mitotic cells (Heart)': '0.120', 'Podocytes': '-0.118', 'Ascending Loop of Henle cells': '0.475', 'Intercalated cells': '0.212', 'Cholangiocyte': '0.090', 'NK-cells (Liver)': '-0.005', 'Respiratory ciliated cells': '-0.012', 'Mitotic cells (Lung)': '0.071', 'NK-cells (Lung)': '-0.266', 'B-cells (Lung)': '-0.296', 'Alpha cells': '0.270', 'Beta cells': '0.152', 'Prostate glandular cells': '0.764', 'Prostate basal glandular cells': '0.540', 'Urothelial cells': '0.205', 'Keratinocyte (other)': '0.510', 'Keratinocyte (granular)': '0.055', 'Hair cortex cells': '0.080', 'Inner root sheath cells': '0.131', 'Outer root sheath cells': '0.175', 'Sebaceous gland cells': '0.156', 'Eccrine sweat gland cells': '-0.207', 'Adipocytes (Skin)': '-0.244', 'Mitotic cells (Skin)': '0.442', 'Parietal cells': '0.654', 'Chief cells': '0.649', 'Gastric mucous cells': '0.781', 'Gastric enteroendocrine cells': '0.590', 'Mitotic cells (Stomach)': '0.445', 'Parafollicular cells': '0.173', 'Thyroid glandular cells': '0.865', 'Mitotic cells (Thyroid)': '-0.081', 'Adrenal cortex cells': '0.051', 'Adrenal medulla cells': '0.087', 'Mitotic cells (Adrenal gland)': '0.072', 'Minor salivary glandular cells': '0.371', 'Minor salivary gland ductal cells': '-0.142', 'Minor salivary gland basal cells': '0.582', 'Mitotic cells (Minor salivary gland)': '0.567', 'Adipocytes (Minor salivary gland)': '0.050', 'Somatotropes': '0.121', 'Lactotropes': '0.322', 'Gonadotropes': '0.330', 'Corticotropes': '0.180', 'Thyrotropes': '0.496', 'Undifferentiated cells (Pituitary gland)': '-0.108', 'Mitotic cells (Spleen)': '-0.228', 'Platelets': '-0.050', 'Erythrocytes': '-0.158', 'Hematopoietic stem cells': '-0.211', 'B-cells (Spleen)': '0.266', 'NK-cells (Spleen)': '0.309', 'Amygdala excitatory': '1.0', 'Cerebellar inhibitory': '0.9', 'Cge interneuron': '0.7', 'Deep-layer corticothalamic and 6b': '1.5', 'Deep-layer intratelencephalic': '0.7', 'Deep-layer near-projecting': '0.7', 'Eccentric medium spiny neuron': '0.6', 'Hippocampal ca1-3': '1.9', 'Hippocampal ca4': '1.2', 'Hippocampal dentate gyrus': '1.1', 'Lamp5-lhx6 and chandelier': '0.5', 'Lower rhombic lip': '0.8', 'Mammillary body': '0.6', 'Medium spiny neuron': '0.7', 'Mge interneuron': '1.7', 'Midbrain-derived inhibitory': '0.7', 'Miscellaneous': '0.9', 'Splatter': '3.8', 'Thalamic excitatory': '0.5', 'Upper rhombic lip': '0.8', 'Upper-layer intratelencephalic': '0.6', 'Astrocyte': '4.4', 'Bergmann glia': '0.2', 'Central nervous system macrophage': '0.6', 'Choroid plexus epithelial cell': '52.1', 'Committed oligodendrocyte precursor': '41.5', 'Ependymal cell': '4.8', 'Oligodendrocyte': '53.1', 'Oligodendrocyte precursor cell': '2.4', 'Endothelial cell': '0.7', 'Pericyte': '0.3', 'Vascular associated smooth muscle cell': '0.0', 'Fibroblast': '17.4', 'Leukocyte': '1.1', 'Basophil': '0.0', 'Eosinophil': '0.0', 'Neutrophil': '0.0', 'Classical monocyte': '0.0', 'Non-classical monocyte': '0.0', 'Intermediate monocyte': '0.0', 'T-reg': '2.3', 'GdT-cell': '0.0', 'MAIT T-cell': '0.0', 'Memory CD4 T-cell': '0.0', 'Naive CD4 T-cell': '0.1', 'Memory CD8 T-cell': '0.2', 'Naive CD8 T-cell': '0.3', 'Memory B-cell': '0.0', 'Naive B-cell': '0.1', 'Plasmacytoid DC': '46.6', 'Myeloid DC': '8.5', 'NK-cell': '0.1', 'Total PBMC': '0.7', 'Vd2 gdTCR': '0.0', 'Memory CD4 T-cell Th1\\/Th17': '0.1', 'Memory CD4 T-cell Th17': '0.2', 'Memory CD4 T-cell Th2': '2.9', 'Non-Vd2 gdTCR': '0.1', 'Memory CD4 T-cell Th1': '0.3', 'Memory CD4 T-cell TFH': '0.5', 'Terminal effector memory CD4 T-cell': '0.0', 'Central memory CD8 T-cell': '4.8', 'Effector memory CD8 T-cell': '0.0', 'Terminal effector memory CD8 T-cell': '0.6', 'Non-switched memory B-cell': '0.0', 'Plasmablast': '3.3', 'Switched memory B-cell': '0.0', 'Exhausted memory B-cell': '0.7', 'Progenitor cell': '2.3', 'Memory T-reg': '1.3', 'Naive CD4 T-cell activated': '0.3', 'Naive CD8 T-cell activated': '0.6', 'Naive T-reg': '0.1'}
1O6S, 2O72, 2OMT, 2OMU, 2OMV, 2OMX, 2OMY, 2OMZ, 3FF7, 3FF8, 3L6X, 3L6Y, 4ZT1, 4ZTE, 6CXY, 6OLE, 6OLF, 6OLG, 6VEL, 7STZ, 8H62
{'Adipose Tissue': 1.2125261088039867, 'Adrenal Gland': 0.1914223992248062, 'Bladder': 39.2033519047619, 'Blood': 1.340954264800861, 'Blood Vessel': 0.3121561692883895, 'Brain': 0.8550442199091597, 'Breast': 38.54918344226579, 'Cervix Uteri': 23.539115789473684, 'Colon': 43.41292142490372, 'Esophagus': 53.97513367404844, 'Fallopian Tube': 14.900277777777776, 'Heart': 0.119140469221835, 'Kidney': 25.040449438202245, 'Liver': 26.60802654867257, 'Lung': 35.447986366782004, 'Muscle': 0.1378936151930261, 'Nerve': 17.518468982229404, 'Ovary': 3.6515122222222223, 'Pancreas': 56.89676829268293, 'Pituitary': 24.68741660777385, 'Prostate': 61.279967346938776, 'Salivary Gland': 92.01685185185184, 'Skin': 79.77571720232172, 'Small Intestine': 71.7519320855615, 'Spleen': 10.061029045643156, 'Stomach': 58.07813805013927, 'Testis': 0.8144204986149585, 'Thyroid': 135.176797856049, 'Uterus': 1.442593943661972, 'Vagina': 86.52345512820513}
ZC3HC1
MAAPCEGQAFAVGVEKNWGAVVRSPEGTPQKIRQLIDEGIAPEEGGVDAKDTSATSQSVNGSPQAEQPSLESTSKEAFFSRVETFSSLKWAGKPFELSPLVCAKYGWVTVECDMLKCSSCQAFLCASLQPAFDFDRYKQRCAELKKALCTAHEKFCFWPDSPSPDRFGMLPLDEPAILVSEFLDRFQSLCHLDLQLPSLRPEDLKTMCLTEDKISLLLHLLEDELDHRTDERKTTIKLGSDIQVHVTACILSVCGWACSSSLESMQLSLITCSQCMRKVGLWGFQQIESSMTDLDASFGLTSSPIPGLEGRPERLPLVPESPRRMMTRSQDATFSPGSEQAEKSPGPIVSRTRSWDSSSPVDRPEPEAASPTTRTRPVTRSMGTGDTPGLEVPSSPLRKAKRARLCSSSSSDTSSRSFFDPTSQHRDWCPWVNITLGKESRENGGTEPDASAPAEPGWKAVLTILLAHKQSSQPAETDSMSLSEKSRKVFRIFRQWESLCSC
Homo sapiens
Nucleus, Nucleus envelope
Low tissue specificity
{'Ciliated cells': '4.7', 'Basal respiratory cells': '16.0', 'Club cells': '6.7', 'Ionocytes': '9.2', 'Mucus glandular cells': '3.7', 'Serous glandular cells': '6.9', 'Gastric mucus-secreting cells': '4.1', 'Proximal enterocytes': '2.5', 'Paneth cells': '3.8', 'Distal enterocytes': '3.2', 'Intestinal goblet cells': '3.6', 'Exocrine glandular cells': '-0.674', 'Basal prostatic cells': '5.4', 'Prostatic glandular cells': '4.9', 'Breast glandular cells': '0.229', 'Breast myoepithelial cells': '0.105', 'Glandular and luminal cells': '2.6', 'Secretory cells': '5.8', 'Basal keratinocytes': '3.7', 'Suprabasal keratinocytes': '2.9', 'Basal squamous epithelial cells': '8.2', 'Squamous epithelial cells': '4.4', 'Alveolar cells type 1': '-0.118', 'Alveolar cells type 2': '0.194', 'Salivary duct cells': '4.9', 'Ductal cells': '0.639', 'Hepatocytes': '0.212', 'Cholangiocytes': '0.0', 'Proximal tubular cells': '0.297', 'Distal tubular cells': '24.6', 'Collecting duct cells': '3.9', 'Mesothelial cells': '0.206', 'Sertoli cells': '0.049', 'Granulosa cells': '9.5', 'Enteroendocrine cells': '4.5', 'Pancreatic endocrine cells': '11.9', 'Leydig cells': '-0.044', 'Excitatory neurons': '13.3', 'Inhibitory neurons': '15.1', 'Cone photoreceptor cells': '0.0', 'Rod photoreceptor cells': '4.1', 'Bipolar cells': '7.6', 'Horizontal cells': '3.1', 'Astrocytes': '11.8', 'Oligodendrocyte precursor cells': '10.8', 'Oligodendrocytes': '11.6', 'Microglial cells': '8.9', 'Muller glia cells': '8.1', 'Schwann cells': '0.043', 'Spermatogonia': '0.216', 'Spermatocytes': '0.477', 'Early spermatids': '0.447', 'Late spermatids': '0.003', 'Oocytes': '22.1', 'Cytotrophoblasts': '20.2', 'Syncytiotrophoblasts': '7.2', 'Extravillous trophoblasts': '17.9', 'Endothelial cells': '7.9', 'Lymphatic endothelial cells': '3.1', 'Cardiomyocytes': '0.714', 'Skeletal myocytes': '-0.046', 'Smooth muscle cells': '6.5', 'Adipocytes': '4.7', 'Melanocytes': '0.151', 'Fibroblasts': '7.6', 'Peritubular cells': '-0.144', 'Endometrial stromal cells': '5.4', 'Ovarian stromal cells': '8.1', 'Undifferentiated cells': '6.7', 'T-cells': '6.3', 'B-cells': '7.0', 'Plasma cells': '8.6', 'Nk-cells': '5.2', 'Granulocytes': '8.3', 'Monocytes': '3.7', 'Macrophages': '4.1', 'Hofbauer cells': '8.0', 'Kupffer cells': '5.9', 'Dendritic cells': '4.0', 'Langerhans cells': '0.296', 'Erythroid cells': '0.027', 'Adipocytes (Subcutaneous)': '0.201', 'Adipocytes (Visceral)': '0.144', 'Breast glandular cells (progenitors)': '0.110', 'Adipocytes (Breast)': '0.095', 'Colon enterocytes': '-0.169', 'Colon enteroendocrine cells': '0.227', 'Enteric glia cells': '0.049', 'Mitotic cells (Colon)': '-0.208', 'Mitotic cells (Heart)': '0.489', 'Podocytes': '-0.211', 'Ascending Loop of Henle cells': '0.471', 'Intercalated cells': '-0.082', 'Cholangiocyte': '0.179', 'NK-cells (Liver)': '-0.077', 'Respiratory ciliated cells': '-0.063', 'Mitotic cells (Lung)': '0.227', 'NK-cells (Lung)': '-0.191', 'B-cells (Lung)': '-0.257', 'Alpha cells': '0.383', 'Beta cells': '0.259', 'Prostate glandular cells': '-0.079', 'Prostate basal glandular cells': '0.237', 'Urothelial cells': '0.049', 'Keratinocyte (other)': '0.006', 'Keratinocyte (granular)': '-0.236', 'Hair cortex cells': '0.088', 'Inner root sheath cells': '0.078', 'Outer root sheath cells': '0.286', 'Sebaceous gland cells': '0.270', 'Eccrine sweat gland cells': '0.153', 'Adipocytes (Skin)': '0.148', 'Mitotic cells (Skin)': '0.314', 'Parietal cells': '-0.573', 'Chief cells': '-0.504', 'Gastric mucous cells': '-0.352', 'Gastric enteroendocrine cells': '-0.381', 'Mitotic cells (Stomach)': '0.146', 'Parafollicular cells': '0.011', 'Thyroid glandular cells': '0.253', 'Mitotic cells (Thyroid)': '0.031', 'Adrenal cortex cells': '0.577', 'Adrenal medulla cells': '0.022', 'Mitotic cells (Adrenal gland)': '0.486', 'Minor salivary glandular cells': '0.421', 'Minor salivary gland ductal cells': '0.086', 'Minor salivary gland basal cells': '0.175', 'Mitotic cells (Minor salivary gland)': '0.351', 'Adipocytes (Minor salivary gland)': '0.198', 'Somatotropes': '-0.074', 'Lactotropes': '-0.090', 'Gonadotropes': '-0.006', 'Corticotropes': '-0.011', 'Thyrotropes': '0.087', 'Undifferentiated cells (Pituitary gland)': '0.288', 'Mitotic cells (Spleen)': '-0.205', 'Platelets': '-0.024', 'Erythrocytes': '-0.055', 'Hematopoietic stem cells': '-0.266', 'B-cells (Spleen)': '0.245', 'NK-cells (Spleen)': '0.228', 'Amygdala excitatory': '22.4', 'Cerebellar inhibitory': '20.7', 'Cge interneuron': '21.2', 'Deep-layer corticothalamic and 6b': '22.1', 'Deep-layer intratelencephalic': '20.9', 'Deep-layer near-projecting': '21.6', 'Eccentric medium spiny neuron': '22.3', 'Hippocampal ca1-3': '20.7', 'Hippocampal ca4': '20.2', 'Hippocampal dentate gyrus': '24.3', 'Lamp5-lhx6 and chandelier': '22.8', 'Lower rhombic lip': '18.3', 'Mammillary body': '25.1', 'Medium spiny neuron': '22.4', 'Mge interneuron': '25.9', 'Midbrain-derived inhibitory': '25.0', 'Miscellaneous': '19.3', 'Splatter': '21.4', 'Thalamic excitatory': '21.2', 'Upper rhombic lip': '20.1', 'Upper-layer intratelencephalic': '23.0', 'Astrocyte': '23.2', 'Bergmann glia': '26.5', 'Central nervous system macrophage': '28.4', 'Choroid plexus epithelial cell': '37.9', 'Committed oligodendrocyte precursor': '22.1', 'Ependymal cell': '13.8', 'Oligodendrocyte': '21.0', 'Oligodendrocyte precursor cell': '26.4', 'Endothelial cell': '21.4', 'Pericyte': '20.3', 'Vascular associated smooth muscle cell': '16.7', 'Fibroblast': '23.6', 'Leukocyte': '17.9', 'Basophil': '17.3', 'Eosinophil': '23.8', 'Neutrophil': '0.7', 'Classical monocyte': '6.9', 'Non-classical monocyte': '11.3', 'Intermediate monocyte': '16.2', 'T-reg': '23.0', 'GdT-cell': '26.0', 'MAIT T-cell': '16.6', 'Memory CD4 T-cell': '26.7', 'Naive CD4 T-cell': '20.0', 'Memory CD8 T-cell': '27.5', 'Naive CD8 T-cell': '17.7', 'Memory B-cell': '39.5', 'Naive B-cell': '16.1', 'Plasmacytoid DC': '18.0', 'Myeloid DC': '22.7', 'NK-cell': '15.2', 'Total PBMC': '19.0', 'Vd2 gdTCR': '13.3', 'Memory CD4 T-cell TFH': '19.3', 'Memory CD4 T-cell Th2': '15.9', 'Memory CD4 T-cell Th17': '15.3', 'Memory CD4 T-cell Th1\\/Th17': '14.0', 'Non-Vd2 gdTCR': '24.1', 'Memory CD4 T-cell Th1': '16.7', 'Terminal effector memory CD4 T-cell': '25.5', 'Central memory CD8 T-cell': '18.3', 'Effector memory CD8 T-cell': '22.1', 'Terminal effector memory CD8 T-cell': '17.4', 'Switched memory B-cell': '22.6', 'Plasmablast': '37.6', 'Non-switched memory B-cell': '17.1', 'Exhausted memory B-cell': '15.9', 'Progenitor cell': '33.7', 'Naive CD4 T-cell activated': '25.9', 'Naive CD8 T-cell activated': '28.5', 'Memory T-reg': '18.2', 'Naive T-reg': '20.4'}
null
{'Adipose Tissue': 10.769715946843853, 'Adrenal Gland': 12.905678294573644, 'Bladder': 12.712142857142856, 'Blood': 6.0507692142088265, 'Blood Vessel': 10.550713857677902, 'Brain': 6.8471915215745645, 'Breast': 11.629217864923747, 'Cervix Uteri': 15.34284210526316, 'Colon': 10.611590372272143, 'Esophagus': 10.180880553633218, 'Fallopian Tube': 12.78077777777778, 'Heart': 7.6723606271777, 'Kidney': 8.503696629213483, 'Liver': 7.882867256637168, 'Lung': 8.977420415224913, 'Muscle': 15.73590909090909, 'Nerve': 14.589857835218092, 'Ovary': 13.68907777777778, 'Pancreas': 3.894026829268293, 'Pituitary': 10.96062897526502, 'Prostate': 12.646583673469388, 'Salivary Gland': 8.216641975308642, 'Skin': 11.05276119402985, 'Small Intestine': 9.749320855614974, 'Spleen': 16.61602489626556, 'Stomach': 8.661270194986074, 'Testis': 26.577894736842108, 'Thyroid': 12.487415007656969, 'Uterus': 17.05050704225352, 'Vagina': 11.460121794871794}
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[41.86, 41.3, 46.01, 58.06, 50.35, 41.13, 49.82, 38.17, 41.35, 35.64, 35.33, 34.13, 36.0, 30.7, 34.57, 34.19, 35.53, 30.43, 28.1, 32.73, 29.49, 35.32, 36.48, 40.09, 40.44, 41.35, 41.16, 56.7, 59.91, 59.33, 61.06, 63.37, 69.79, 67.26, 67.89, 65.83, 62.29, 63.06, 43.65, 46.39, 43.02, 50.27, 44.21, 36.48, 44.19, 34.26, 44.58, 39.89, 45.08, 40.8, 42.82, 43.53, 43.25, 42.21, 35.82, 43.22, 37.94, 47.01, 41.42, 43.37, 37.65, 37.95, 36.22, 35.61, 38.62, 36.67, 33.59, 45.81, 53.95, 67.73, 78.39, 86.06, 89.12, 94.61, 94.25, 94.96, 95.43, 97.05, 96.6, 95.86, 97.33, 97.13, 95.47, 96.66, 96.91, 93.11, 89.33, 90.48, 93.68, 94.96, 90.14, 87.39, 92.46, 92.48, 90.54, 92.24, 95.5, 95.49, 96.98, 96.11, 96.35, 97.87, 97.58, 96.85, 97.59, 97.53, 98.5, 98.33, 97.72, 97.25, 95.68, 95.24, 95.16, 97.44, 98.47, 98.52, 98.36, 96.45, 95.86, 97.09, 97.41, 98.26, 98.43, 98.13, 96.75, 95.75, 93.4, 90.55, 83.51, 78.94, 76.67, 80.16, 90.22, 90.47, 91.42, 91.28, 92.61, 92.74, 93.9, 94.42, 94.69, 95.75, 96.59, 97.33, 96.92, 97.78, 98.16, 98.03, 96.96, 97.26, 97.87, 98.24, 97.62, 95.07, 91.75, 96.39, 94.83, 96.05, 95.24, 93.81, 94.42, 95.94, 96.14, 94.84, 91.93, 92.26, 94.07, 92.4, 92.19, 94.34, 93.33, 92.91, 91.66, 93.74, 93.83, 94.14, 94.75, 95.76, 95.95, 95.53, 96.01, 97.21, 96.12, 95.43, 96.84, 96.21, 93.74, 93.34, 95.09, 92.72, 89.97, 89.95, 90.94, 91.35, 91.31, 93.69, 94.43, 93.37, 92.48, 88.1, 84.1, 84.71, 83.72, 84.36, 82.18, 82.41, 87.23, 86.95, 87.72, 88.97, 86.16, 91.09, 93.18, 92.6, 91.95, 94.21, 94.83, 94.25, 91.97, 93.57, 93.36, 90.62, 89.9, 90.44, 86.8, 84.16, 81.68, 79.63, 65.93, 59.92, 59.16, 52.46, 35.13, 40.79, 41.12, 51.59, 53.18, 58.07, 55.88, 68.26, 82.61, 88.01, 89.27, 92.38, 93.0, 93.54, 94.31, 95.6, 96.07, 95.77, 97.11, 97.3, 96.13, 96.37, 97.04, 98.01, 96.5, 93.53, 83.62, 68.11, 55.02, 49.62, 49.39, 50.51, 57.79, 64.71, 76.65, 87.44, 91.96, 95.79, 96.12, 96.62, 94.08, 94.34, 94.59, 93.9, 94.06, 93.91, 94.03, 93.17, 93.41, 88.75, 89.27, 93.88, 93.26, 92.41, 90.04, 83.74, 74.55, 59.82, 53.32, 45.36, 42.14, 45.87, 38.91, 41.45, 39.24, 37.8, 36.65, 40.22, 37.21, 38.8, 36.92, 36.55, 42.02, 36.13, 36.8, 42.25, 38.71, 36.59, 37.16, 35.57, 38.81, 34.58, 34.71, 31.98, 39.11, 38.13, 42.17, 42.86, 40.41, 50.11, 43.1, 52.93, 42.14, 52.57, 51.17, 42.91, 54.23, 44.68, 45.98, 39.47, 34.58, 37.71, 30.66, 38.02, 35.0, 43.96, 38.88, 40.98, 39.51, 39.88, 39.25, 42.22, 43.71, 37.59, 40.02, 43.27, 43.31, 37.99, 39.96, 38.03, 42.25, 34.82, 42.37, 37.73, 34.95, 36.92, 35.76, 43.69, 43.82, 41.72, 43.37, 41.25, 38.18, 42.51, 36.38, 35.7, 39.34, 33.26, 49.49, 41.72, 36.46, 43.06, 41.85, 40.47, 40.38, 40.3, 45.03, 46.08, 43.49, 43.11, 38.31, 37.45, 38.9, 37.56, 39.08, 45.08, 37.45, 43.06, 38.86, 49.06, 40.94, 32.38, 38.54, 41.0, 32.92, 41.63, 43.82, 38.77, 49.19, 53.12, 46.99, 55.67, 45.68, 45.6, 39.1, 40.84, 40.29, 43.03, 42.0, 46.36, 42.18, 56.63, 76.21, 86.43, 91.53, 92.67, 94.69, 93.89, 94.41, 93.41, 92.75, 94.34, 95.35, 93.85, 92.01, 93.1, 95.17, 94.44, 95.46, 93.46, 86.75, 78.93, 60.69, 48.57, 44.63, 37.2, 36.3, 31.25, 35.67, 35.67, 33.3, 32.96, 32.78, 34.72, 35.9, 39.12, 37.08, 37.99, 43.63, 50.46, 56.31, 73.81, 86.46, 92.38, 93.85, 94.88, 94.66, 94.17, 95.25, 95.28, 94.75, 94.85, 95.77, 94.62, 93.38, 91.07, 86.24, 84.12, 81.72, 71.95, 60.22, 55.16, 48.44, 47.8, 46.97, 45.53, 52.87, 59.48, 71.09, 71.27, 73.4, 77.65, 75.73, 76.03, 81.44, 79.26, 74.61, 75.11, 81.45, 73.0, 73.35, 76.44, 75.45, 65.31, 63.97, 73.42, 68.03, 55.38, 56.47, 40.82]
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null
Component of an E-cadherin/ catenin adhesion complex composed of at least E-cadherin/CDH1, beta-catenin/CTNNB1 or gamma-catenin/JUP, and potentially alpha-catenin/CTNNA1. Forms a ternary complex composed of ADAM10, CADH1 and EPHA4,
null
null
KLRG1, SPEF1, DLGAP5, AJAP1, RAPGEF2, RAB8B, PIP5K1C, PKP2, TRPV4, CTNNB1, CAV1, DDR1, TBC1D2, CTNNA1, JUP, CTNND1, PSEN1, LIMA1, CDH1, JUP, ADAM10, CADH1 , EPHA4,
null
null
null
null
Homodimer
null
79.91949
0.474025
68.031414
0.581952
1,580
P12830
Q86XJ1
null
degron_data
CDH1
MGPWSRSLSALLLLLQVSSWLCQEPEPCHPGFDAESYTFTVPRRHLERGRVLGRVNFEDCTGRQRTAYFSLDTRFKVGTDGVITVKRPLRFHNPQIHFLVYAWDSTYRKFSTKVTLNTVGHHHRPPPHQASVSGIQAELLTFPNSSPGLRRQKRDWVIPPISCPENEKGPFPKNLVQIKSNKDKEGKVFYSITGQGADTPPVGVFIIERETGWLKVTEPLDRERIATYTLFSHAVSSNGNAVEDPMEILITVTDQNDNKPEFTQEVFKGSVMEGALPGTSVMEVTATDADDDVNTYNAAIAYTILSQDPELPDKNMFTINRNTGVISVVTTGLDRESFPTYTLVVQAADLQGEGLSTTATAVITVTDTNDNPPIFNPTTYKGQVPENEANVVITTLKVTDADAPNTPAWEAVYTILNDDGGQFVVTTNPVNNDGILKTAKGLDFEAKQQYILHVAVTNVVPFEVSLTTSTATVTVDVLDVNEAPIFVPPEKRVEVSEDFGVGQEITSYTAQEPDTFMEQKITYRIWRDTANWLEINPDTGAISTRAELDREDFEHVKNSTYTALIIATDNGSPVATGTGTLLLILSDVNDNAPIPEPRTIFFCERNPKPQVINIIDADLPPNTSPFTAELTHGASANWTIQYNDPTQESIILKPKMALEVGDYKINLKLMDNQNKDQVTTLEVSVCDCEGAAGVCRKAQPVEAGLQIPAILGILGGILALLILILLLLLFLRRRAVVKEPLLPPEDDTRDNVYYYDEEGGGEEDQDFDLSQLHRGLDARPEVTRNDVAPTLMSVPRYLPRPANPDEIGNFIDENLKAADTDPTAPPYDSLLVFDYEGSGSEAASLSSLNSSESDKDQDYDYLNEWGNRFKKLADMYGGGEDD
Homo sapiens
Cell junction, adherens junction, Cell membrane, Endosome, Golgi apparatus, trans-Golgi network, Cytoplasm, Cell junction, desmosome
Tissue enhanced (parathyroid)
{'Ciliated cells': '119.1', 'Basal respiratory cells': '71.1', 'Club cells': '97.3', 'Ionocytes': '81.0', 'Mucus glandular cells': '155.0', 'Serous glandular cells': '67.8', 'Gastric mucus-secreting cells': '133.2', 'Proximal enterocytes': '140.9', 'Paneth cells': '125.1', 'Distal enterocytes': '307.5', 'Intestinal goblet cells': '173.5', 'Exocrine glandular cells': '-0.605', 'Basal prostatic cells': '68.3', 'Prostatic glandular cells': '186.7', 'Breast glandular cells': '0.773', 'Breast myoepithelial cells': '0.700', 'Glandular and luminal cells': '313.0', 'Secretory cells': '82.3', 'Basal keratinocytes': '102.5', 'Suprabasal keratinocytes': '162.6', 'Basal squamous epithelial cells': '51.0', 'Squamous epithelial cells': '106.9', 'Alveolar cells type 1': '0.437', 'Alveolar cells type 2': '0.706', 'Salivary duct cells': '95.9', 'Ductal cells': '0.541', 'Hepatocytes': '0.600', 'Cholangiocytes': '129.7', 'Proximal tubular cells': '0.042', 'Distal tubular cells': '0.0', 'Collecting duct cells': '143.9', 'Mesothelial cells': '0.799', 'Sertoli cells': '0.252', 'Granulosa cells': '12.9', 'Enteroendocrine cells': '92.4', 'Pancreatic endocrine cells': '78.1', 'Leydig cells': '0.264', 'Excitatory neurons': '0.7', 'Inhibitory neurons': '1.3', 'Cone photoreceptor cells': '0.0', 'Rod photoreceptor cells': '0.0', 'Bipolar cells': '0.2', 'Horizontal cells': '0.6', 'Astrocytes': '0.6', 'Oligodendrocyte precursor cells': '0.5', 'Oligodendrocytes': '29.9', 'Microglial cells': '0.9', 'Muller glia cells': '0.1', 'Schwann cells': '0.131', 'Spermatogonia': '0.392', 'Spermatocytes': '0.193', 'Early spermatids': '-0.217', 'Late spermatids': '-0.290', 'Oocytes': '16.9', 'Cytotrophoblasts': '119.2', 'Syncytiotrophoblasts': '45.0', 'Extravillous trophoblasts': '24.9', 'Endothelial cells': '6.1', 'Lymphatic endothelial cells': '0.4', 'Cardiomyocytes': '0.135', 'Skeletal myocytes': '0.107', 'Smooth muscle cells': '5.8', 'Adipocytes': '2.1', 'Melanocytes': '0.335', 'Fibroblasts': '6.5', 'Peritubular cells': '0.210', 'Endometrial stromal cells': '27.7', 'Ovarian stromal cells': '0.7', 'Undifferentiated cells': '101.6', 'T-cells': '2.9', 'B-cells': '4.4', 'Plasma cells': '6.1', 'Nk-cells': '0.0', 'Granulocytes': '8.4', 'Monocytes': '0.0', 'Macrophages': '6.0', 'Hofbauer cells': '4.3', 'Kupffer cells': '1.0', 'Dendritic cells': '5.9', 'Langerhans cells': '0.304', 'Erythroid cells': '0.036', 'Adipocytes (Subcutaneous)': '-0.081', 'Adipocytes (Visceral)': '-0.209', 'Breast glandular cells (progenitors)': '0.538', 'Adipocytes (Breast)': '-0.689', 'Colon enterocytes': '0.790', 'Colon enteroendocrine cells': '0.112', 'Enteric glia cells': '-0.048', 'Mitotic cells (Colon)': '0.299', 'Mitotic cells (Heart)': '0.120', 'Podocytes': '-0.118', 'Ascending Loop of Henle cells': '0.475', 'Intercalated cells': '0.212', 'Cholangiocyte': '0.090', 'NK-cells (Liver)': '-0.005', 'Respiratory ciliated cells': '-0.012', 'Mitotic cells (Lung)': '0.071', 'NK-cells (Lung)': '-0.266', 'B-cells (Lung)': '-0.296', 'Alpha cells': '0.270', 'Beta cells': '0.152', 'Prostate glandular cells': '0.764', 'Prostate basal glandular cells': '0.540', 'Urothelial cells': '0.205', 'Keratinocyte (other)': '0.510', 'Keratinocyte (granular)': '0.055', 'Hair cortex cells': '0.080', 'Inner root sheath cells': '0.131', 'Outer root sheath cells': '0.175', 'Sebaceous gland cells': '0.156', 'Eccrine sweat gland cells': '-0.207', 'Adipocytes (Skin)': '-0.244', 'Mitotic cells (Skin)': '0.442', 'Parietal cells': '0.654', 'Chief cells': '0.649', 'Gastric mucous cells': '0.781', 'Gastric enteroendocrine cells': '0.590', 'Mitotic cells (Stomach)': '0.445', 'Parafollicular cells': '0.173', 'Thyroid glandular cells': '0.865', 'Mitotic cells (Thyroid)': '-0.081', 'Adrenal cortex cells': '0.051', 'Adrenal medulla cells': '0.087', 'Mitotic cells (Adrenal gland)': '0.072', 'Minor salivary glandular cells': '0.371', 'Minor salivary gland ductal cells': '-0.142', 'Minor salivary gland basal cells': '0.582', 'Mitotic cells (Minor salivary gland)': '0.567', 'Adipocytes (Minor salivary gland)': '0.050', 'Somatotropes': '0.121', 'Lactotropes': '0.322', 'Gonadotropes': '0.330', 'Corticotropes': '0.180', 'Thyrotropes': '0.496', 'Undifferentiated cells (Pituitary gland)': '-0.108', 'Mitotic cells (Spleen)': '-0.228', 'Platelets': '-0.050', 'Erythrocytes': '-0.158', 'Hematopoietic stem cells': '-0.211', 'B-cells (Spleen)': '0.266', 'NK-cells (Spleen)': '0.309', 'Amygdala excitatory': '1.0', 'Cerebellar inhibitory': '0.9', 'Cge interneuron': '0.7', 'Deep-layer corticothalamic and 6b': '1.5', 'Deep-layer intratelencephalic': '0.7', 'Deep-layer near-projecting': '0.7', 'Eccentric medium spiny neuron': '0.6', 'Hippocampal ca1-3': '1.9', 'Hippocampal ca4': '1.2', 'Hippocampal dentate gyrus': '1.1', 'Lamp5-lhx6 and chandelier': '0.5', 'Lower rhombic lip': '0.8', 'Mammillary body': '0.6', 'Medium spiny neuron': '0.7', 'Mge interneuron': '1.7', 'Midbrain-derived inhibitory': '0.7', 'Miscellaneous': '0.9', 'Splatter': '3.8', 'Thalamic excitatory': '0.5', 'Upper rhombic lip': '0.8', 'Upper-layer intratelencephalic': '0.6', 'Astrocyte': '4.4', 'Bergmann glia': '0.2', 'Central nervous system macrophage': '0.6', 'Choroid plexus epithelial cell': '52.1', 'Committed oligodendrocyte precursor': '41.5', 'Ependymal cell': '4.8', 'Oligodendrocyte': '53.1', 'Oligodendrocyte precursor cell': '2.4', 'Endothelial cell': '0.7', 'Pericyte': '0.3', 'Vascular associated smooth muscle cell': '0.0', 'Fibroblast': '17.4', 'Leukocyte': '1.1', 'Basophil': '0.0', 'Eosinophil': '0.0', 'Neutrophil': '0.0', 'Classical monocyte': '0.0', 'Non-classical monocyte': '0.0', 'Intermediate monocyte': '0.0', 'T-reg': '2.3', 'GdT-cell': '0.0', 'MAIT T-cell': '0.0', 'Memory CD4 T-cell': '0.0', 'Naive CD4 T-cell': '0.1', 'Memory CD8 T-cell': '0.2', 'Naive CD8 T-cell': '0.3', 'Memory B-cell': '0.0', 'Naive B-cell': '0.1', 'Plasmacytoid DC': '46.6', 'Myeloid DC': '8.5', 'NK-cell': '0.1', 'Total PBMC': '0.7', 'Vd2 gdTCR': '0.0', 'Memory CD4 T-cell Th1\\/Th17': '0.1', 'Memory CD4 T-cell Th17': '0.2', 'Memory CD4 T-cell Th2': '2.9', 'Non-Vd2 gdTCR': '0.1', 'Memory CD4 T-cell Th1': '0.3', 'Memory CD4 T-cell TFH': '0.5', 'Terminal effector memory CD4 T-cell': '0.0', 'Central memory CD8 T-cell': '4.8', 'Effector memory CD8 T-cell': '0.0', 'Terminal effector memory CD8 T-cell': '0.6', 'Non-switched memory B-cell': '0.0', 'Plasmablast': '3.3', 'Switched memory B-cell': '0.0', 'Exhausted memory B-cell': '0.7', 'Progenitor cell': '2.3', 'Memory T-reg': '1.3', 'Naive CD4 T-cell activated': '0.3', 'Naive CD8 T-cell activated': '0.6', 'Naive T-reg': '0.1'}
1O6S, 2O72, 2OMT, 2OMU, 2OMV, 2OMX, 2OMY, 2OMZ, 3FF7, 3FF8, 3L6X, 3L6Y, 4ZT1, 4ZTE, 6CXY, 6OLE, 6OLF, 6OLG, 6VEL, 7STZ, 8H62
{'Adipose Tissue': 1.2125261088039867, 'Adrenal Gland': 0.1914223992248062, 'Bladder': 39.2033519047619, 'Blood': 1.340954264800861, 'Blood Vessel': 0.3121561692883895, 'Brain': 0.8550442199091597, 'Breast': 38.54918344226579, 'Cervix Uteri': 23.539115789473684, 'Colon': 43.41292142490372, 'Esophagus': 53.97513367404844, 'Fallopian Tube': 14.900277777777776, 'Heart': 0.119140469221835, 'Kidney': 25.040449438202245, 'Liver': 26.60802654867257, 'Lung': 35.447986366782004, 'Muscle': 0.1378936151930261, 'Nerve': 17.518468982229404, 'Ovary': 3.6515122222222223, 'Pancreas': 56.89676829268293, 'Pituitary': 24.68741660777385, 'Prostate': 61.279967346938776, 'Salivary Gland': 92.01685185185184, 'Skin': 79.77571720232172, 'Small Intestine': 71.7519320855615, 'Spleen': 10.061029045643156, 'Stomach': 58.07813805013927, 'Testis': 0.8144204986149585, 'Thyroid': 135.176797856049, 'Uterus': 1.442593943661972, 'Vagina': 86.52345512820513}
GAS2L3
MQPAIQVWFGEDLPLSPRSPLTPRHGPGLANVCQYDEWIAVRHEATLLPMQEDLSIWLSGLLGIKVKAEKLLEELDNGVLLCQLIDVLQNMVKTCNSEESGNFPMRKVPCKKDAASGSFFARDNTANFLHWCRDIGVDETYLFESEGLVLHKDPRQVYLCLLEIGRIVSRYGVEPPVLVKLEKEIELEETLLNTSGPEDSISIPKSCCRHEELHEAVKHIAEDPPCSCSHRFSIEYLSEGRYRLGDKILFIRMLHGKHVMVRVGGGWDTLQGFLLKYDPCRILQFATLEQKILAFQKGVSNESVPDSPARTPQPPEMNPLSAVNMFQKQNSKPSVPVSIPKSKEKQGRPPGALVPASSLKGGNLGSMSVRSKLPNSPAASSHPKLKSSKGITKKPQAPSNNASSSLASLNPVGKNTSSPALPRTAPCISESPRKCISSPNTPKAKVIPAQNSADLPESTLLPNKCSGKTQPKYLKHNHISSRDNAVSHLAAHSNSSSKCPKLPKANIPVRPKPSFQSSAKMTKTSSKTIATGLGTQSQPSDGAPQAKPVPAQKLKSALNLNQPVSVSSVSPVKATQKSKDKNIVSATKKQPQNKSAFQKTGPSSLKSPGRTPLSIVSLPQSSTKTQTAPKSAQTVAKSQHSTKGPPRSGKTPASIRKPPSSVKDADSGDKKPTAKKKEDDDHYFVMTGSKKPRK
Homo sapiens
Cytoplasm, Cytoplasm, cytoskeleton
Low tissue specificity
{'Ciliated cells': '2.4', 'Basal respiratory cells': '0.5', 'Club cells': '2.7', 'Ionocytes': '0.0', 'Mucus glandular cells': '6.7', 'Serous glandular cells': '2.9', 'Gastric mucus-secreting cells': '11.2', 'Proximal enterocytes': '2.0', 'Paneth cells': '15.7', 'Distal enterocytes': '9.4', 'Intestinal goblet cells': '15.0', 'Exocrine glandular cells': '-0.443', 'Basal prostatic cells': '0.3', 'Prostatic glandular cells': '0.3', 'Breast glandular cells': '0.278', 'Breast myoepithelial cells': '0.318', 'Glandular and luminal cells': '6.3', 'Secretory cells': '0.5', 'Basal keratinocytes': '3.3', 'Suprabasal keratinocytes': '2.5', 'Basal squamous epithelial cells': '3.8', 'Squamous epithelial cells': '4.0', 'Alveolar cells type 1': '0.003', 'Alveolar cells type 2': '-0.132', 'Salivary duct cells': '3.2', 'Ductal cells': '0.613', 'Hepatocytes': '0.340', 'Cholangiocytes': '9.5', 'Proximal tubular cells': '0.600', 'Distal tubular cells': '0.0', 'Collecting duct cells': '0.0', 'Mesothelial cells': '0.077', 'Sertoli cells': '-0.152', 'Granulosa cells': '3.7', 'Enteroendocrine cells': '7.5', 'Pancreatic endocrine cells': '1.7', 'Leydig cells': '-0.166', 'Excitatory neurons': '2.4', 'Inhibitory neurons': '5.7', 'Cone photoreceptor cells': '0.0', 'Rod photoreceptor cells': '0.7', 'Bipolar cells': '0.5', 'Horizontal cells': '0.6', 'Astrocytes': '0.9', 'Oligodendrocyte precursor cells': '2.4', 'Oligodendrocytes': '0.3', 'Microglial cells': '4.5', 'Muller glia cells': '2.2', 'Schwann cells': '0.259', 'Spermatogonia': '0.197', 'Spermatocytes': '0.653', 'Early spermatids': '0.607', 'Late spermatids': '0.142', 'Oocytes': '4.4', 'Cytotrophoblasts': '10.3', 'Syncytiotrophoblasts': '36.6', 'Extravillous trophoblasts': '5.1', 'Endothelial cells': '3.9', 'Lymphatic endothelial cells': '5.9', 'Cardiomyocytes': '0.238', 'Skeletal myocytes': '0.107', 'Smooth muscle cells': '2.3', 'Adipocytes': '3.4', 'Melanocytes': '0.310', 'Fibroblasts': '1.9', 'Peritubular cells': '-0.079', 'Endometrial stromal cells': '4.8', 'Ovarian stromal cells': '1.3', 'Undifferentiated cells': '10.8', 'T-cells': '0.7', 'B-cells': '1.7', 'Plasma cells': '0.4', 'Nk-cells': '0.3', 'Granulocytes': '6.4', 'Monocytes': '12.1', 'Macrophages': '26.0', 'Hofbauer cells': '13.5', 'Kupffer cells': '8.6', 'Dendritic cells': '0.4', 'Langerhans cells': '0.236', 'Erythroid cells': '0.001', 'Adipocytes (Subcutaneous)': '-0.248', 'Adipocytes (Visceral)': '-0.177', 'Breast glandular cells (progenitors)': '0.124', 'Adipocytes (Breast)': '-0.305', 'Colon enterocytes': '0.127', 'Colon enteroendocrine cells': '0.182', 'Enteric glia cells': '0.677', 'Mitotic cells (Colon)': '0.153', 'Mitotic cells (Heart)': '0.513', 'Podocytes': '0.058', 'Ascending Loop of Henle cells': '-0.028', 'Intercalated cells': '-0.123', 'Cholangiocyte': '0.429', 'NK-cells (Liver)': '-0.172', 'Respiratory ciliated cells': '-0.033', 'Mitotic cells (Lung)': '0.218', 'NK-cells (Lung)': '0.163', 'B-cells (Lung)': '0.099', 'Alpha cells': '0.301', 'Beta cells': '0.178', 'Prostate glandular cells': '-0.352', 'Prostate basal glandular cells': '-0.265', 'Urothelial cells': '-0.149', 'Keratinocyte (other)': '0.058', 'Keratinocyte (granular)': '-0.290', 'Hair cortex cells': '0.257', 'Inner root sheath cells': '0.406', 'Outer root sheath cells': '0.464', 'Sebaceous gland cells': '0.070', 'Eccrine sweat gland cells': '0.181', 'Adipocytes (Skin)': '-0.043', 'Mitotic cells (Skin)': '0.637', 'Parietal cells': '-0.361', 'Chief cells': '-0.405', 'Gastric mucous cells': '-0.056', 'Gastric enteroendocrine cells': '-0.241', 'Mitotic cells (Stomach)': '0.327', 'Parafollicular cells': '-0.023', 'Thyroid glandular cells': '-0.091', 'Mitotic cells (Thyroid)': '0.363', 'Adrenal cortex cells': '0.279', 'Adrenal medulla cells': '0.169', 'Mitotic cells (Adrenal gland)': '0.634', 'Minor salivary glandular cells': '0.365', 'Minor salivary gland ductal cells': '-0.052', 'Minor salivary gland basal cells': '0.323', 'Mitotic cells (Minor salivary gland)': '0.562', 'Adipocytes (Minor salivary gland)': '0.159', 'Somatotropes': '0.500', 'Lactotropes': '-0.005', 'Gonadotropes': '0.025', 'Corticotropes': '-0.217', 'Thyrotropes': '0.007', 'Undifferentiated cells (Pituitary gland)': '-0.141', 'Mitotic cells (Spleen)': '0.231', 'Platelets': '0.302', 'Erythrocytes': '0.006', 'Hematopoietic stem cells': '0.227', 'B-cells (Spleen)': '-0.167', 'NK-cells (Spleen)': '0.031', 'Amygdala excitatory': '3.7', 'Cerebellar inhibitory': '1.4', 'Cge interneuron': '13.0', 'Deep-layer corticothalamic and 6b': '4.1', 'Deep-layer intratelencephalic': '8.9', 'Deep-layer near-projecting': '2.1', 'Eccentric medium spiny neuron': '2.3', 'Hippocampal ca1-3': '4.8', 'Hippocampal ca4': '13.3', 'Hippocampal dentate gyrus': '0.7', 'Lamp5-lhx6 and chandelier': '7.2', 'Lower rhombic lip': '0.6', 'Mammillary body': '0.4', 'Medium spiny neuron': '0.6', 'Mge interneuron': '7.5', 'Midbrain-derived inhibitory': '0.3', 'Miscellaneous': '3.0', 'Splatter': '1.8', 'Thalamic excitatory': '1.1', 'Upper rhombic lip': '0.4', 'Upper-layer intratelencephalic': '0.8', 'Astrocyte': '0.5', 'Bergmann glia': '9.3', 'Central nervous system macrophage': '26.0', 'Choroid plexus epithelial cell': '1.6', 'Committed oligodendrocyte precursor': '2.2', 'Ependymal cell': '0.7', 'Oligodendrocyte': '0.6', 'Oligodendrocyte precursor cell': '3.1', 'Endothelial cell': '3.9', 'Pericyte': '8.8', 'Vascular associated smooth muscle cell': '4.9', 'Fibroblast': '2.5', 'Leukocyte': '4.0', 'Basophil': '1.0', 'Eosinophil': '0.0', 'Neutrophil': '1.7', 'Classical monocyte': '3.4', 'Non-classical monocyte': '3.2', 'Intermediate monocyte': '5.2', 'T-reg': '0.5', 'GdT-cell': '0.0', 'MAIT T-cell': '0.5', 'Memory CD4 T-cell': '0.0', 'Naive CD4 T-cell': '0.0', 'Memory CD8 T-cell': '0.0', 'Naive CD8 T-cell': '0.0', 'Memory B-cell': '0.0', 'Naive B-cell': '0.1', 'Plasmacytoid DC': '1.3', 'Myeloid DC': '6.3', 'NK-cell': '0.1', 'Total PBMC': '1.2', 'Vd2 gdTCR': '0.5', 'Memory CD4 T-cell Th1\\/Th17': '0.0', 'Memory CD4 T-cell Th17': '0.0', 'Memory CD4 T-cell Th2': '0.0', 'Non-Vd2 gdTCR': '0.6', 'Memory CD4 T-cell Th1': '0.0', 'Memory CD4 T-cell TFH': '0.0', 'Terminal effector memory CD4 T-cell': '0.6', 'Central memory CD8 T-cell': '0.5', 'Effector memory CD8 T-cell': '0.5', 'Terminal effector memory CD8 T-cell': '0.6', 'Non-switched memory B-cell': '0.6', 'Plasmablast': '0.4', 'Switched memory B-cell': '0.5', 'Exhausted memory B-cell': '0.6', 'Progenitor cell': '1.0', 'Memory T-reg': '0.1', 'Naive CD4 T-cell activated': '0.0', 'Naive CD8 T-cell activated': '0.0', 'Naive T-reg': '0.0'}
null
{'Adipose Tissue': 2.0403488870431894, 'Adrenal Gland': 0.6854877131782946, 'Bladder': 1.7118809523809524, 'Blood': 0.813095162540366, 'Blood Vessel': 1.408439138576779, 'Brain': 0.2071699943224829, 'Breast': 1.4040612200435731, 'Cervix Uteri': 1.5055, 'Colon': 2.6748033376123237, 'Esophagus': 1.8647095501730104, 'Fallopian Tube': 0.8397, 'Heart': 0.5783803832752613, 'Kidney': 1.379405617977528, 'Liver': 0.5483193805309735, 'Lung': 3.821007958477509, 'Muscle': 0.1911223922789539, 'Nerve': 68.77371567043619, 'Ovary': 1.2130172222222222, 'Pancreas': 0.3242941463414634, 'Pituitary': 0.9778206360424028, 'Prostate': 1.4821008163265308, 'Salivary Gland': 1.218896913580247, 'Skin': 3.557954063018242, 'Small Intestine': 2.3602438502673797, 'Spleen': 0.9764672199170124, 'Stomach': 1.3998392757660167, 'Testis': 3.4675180055401658, 'Thyroid': 0.9932021439509956, 'Uterus': 0.6462521126760563, 'Vagina': 2.1746480769230767}
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null
Component of an E-cadherin/ catenin adhesion complex composed of at least E-cadherin/CDH1, beta-catenin/CTNNB1 or gamma-catenin/JUP, and potentially alpha-catenin/CTNNA1. Forms a ternary complex composed of ADAM10, CADH1 and EPHA4,
null
null
KLRG1, SPEF1, DLGAP5, AJAP1, RAPGEF2, RAB8B, PIP5K1C, PKP2, TRPV4, CTNNB1, CAV1, DDR1, TBC1D2, CTNNA1, JUP, CTNND1, PSEN1, LIMA1, CDH1, JUP, ADAM10, CADH1 , EPHA4,
null
null
null
null
Homodimer
null
79.91949
0.474025
59.767997
0.715202
1,036
P12830
Q8IWB6-3
null
degron_data
CDH1
MGPWSRSLSALLLLLQVSSWLCQEPEPCHPGFDAESYTFTVPRRHLERGRVLGRVNFEDCTGRQRTAYFSLDTRFKVGTDGVITVKRPLRFHNPQIHFLVYAWDSTYRKFSTKVTLNTVGHHHRPPPHQASVSGIQAELLTFPNSSPGLRRQKRDWVIPPISCPENEKGPFPKNLVQIKSNKDKEGKVFYSITGQGADTPPVGVFIIERETGWLKVTEPLDRERIATYTLFSHAVSSNGNAVEDPMEILITVTDQNDNKPEFTQEVFKGSVMEGALPGTSVMEVTATDADDDVNTYNAAIAYTILSQDPELPDKNMFTINRNTGVISVVTTGLDRESFPTYTLVVQAADLQGEGLSTTATAVITVTDTNDNPPIFNPTTYKGQVPENEANVVITTLKVTDADAPNTPAWEAVYTILNDDGGQFVVTTNPVNNDGILKTAKGLDFEAKQQYILHVAVTNVVPFEVSLTTSTATVTVDVLDVNEAPIFVPPEKRVEVSEDFGVGQEITSYTAQEPDTFMEQKITYRIWRDTANWLEINPDTGAISTRAELDREDFEHVKNSTYTALIIATDNGSPVATGTGTLLLILSDVNDNAPIPEPRTIFFCERNPKPQVINIIDADLPPNTSPFTAELTHGASANWTIQYNDPTQESIILKPKMALEVGDYKINLKLMDNQNKDQVTTLEVSVCDCEGAAGVCRKAQPVEAGLQIPAILGILGGILALLILILLLLLFLRRRAVVKEPLLPPEDDTRDNVYYYDEEGGGEEDQDFDLSQLHRGLDARPEVTRNDVAPTLMSVPRYLPRPANPDEIGNFIDENLKAADTDPTAPPYDSLLVFDYEGSGSEAASLSSLNSSESDKDQDYDYLNEWGNRFKKLADMYGGGEDD
Homo sapiens
Cell junction, adherens junction, Cell membrane, Endosome, Golgi apparatus, trans-Golgi network, Cytoplasm, Cell junction, desmosome
Tissue enhanced (parathyroid)
{'Ciliated cells': '119.1', 'Basal respiratory cells': '71.1', 'Club cells': '97.3', 'Ionocytes': '81.0', 'Mucus glandular cells': '155.0', 'Serous glandular cells': '67.8', 'Gastric mucus-secreting cells': '133.2', 'Proximal enterocytes': '140.9', 'Paneth cells': '125.1', 'Distal enterocytes': '307.5', 'Intestinal goblet cells': '173.5', 'Exocrine glandular cells': '-0.605', 'Basal prostatic cells': '68.3', 'Prostatic glandular cells': '186.7', 'Breast glandular cells': '0.773', 'Breast myoepithelial cells': '0.700', 'Glandular and luminal cells': '313.0', 'Secretory cells': '82.3', 'Basal keratinocytes': '102.5', 'Suprabasal keratinocytes': '162.6', 'Basal squamous epithelial cells': '51.0', 'Squamous epithelial cells': '106.9', 'Alveolar cells type 1': '0.437', 'Alveolar cells type 2': '0.706', 'Salivary duct cells': '95.9', 'Ductal cells': '0.541', 'Hepatocytes': '0.600', 'Cholangiocytes': '129.7', 'Proximal tubular cells': '0.042', 'Distal tubular cells': '0.0', 'Collecting duct cells': '143.9', 'Mesothelial cells': '0.799', 'Sertoli cells': '0.252', 'Granulosa cells': '12.9', 'Enteroendocrine cells': '92.4', 'Pancreatic endocrine cells': '78.1', 'Leydig cells': '0.264', 'Excitatory neurons': '0.7', 'Inhibitory neurons': '1.3', 'Cone photoreceptor cells': '0.0', 'Rod photoreceptor cells': '0.0', 'Bipolar cells': '0.2', 'Horizontal cells': '0.6', 'Astrocytes': '0.6', 'Oligodendrocyte precursor cells': '0.5', 'Oligodendrocytes': '29.9', 'Microglial cells': '0.9', 'Muller glia cells': '0.1', 'Schwann cells': '0.131', 'Spermatogonia': '0.392', 'Spermatocytes': '0.193', 'Early spermatids': '-0.217', 'Late spermatids': '-0.290', 'Oocytes': '16.9', 'Cytotrophoblasts': '119.2', 'Syncytiotrophoblasts': '45.0', 'Extravillous trophoblasts': '24.9', 'Endothelial cells': '6.1', 'Lymphatic endothelial cells': '0.4', 'Cardiomyocytes': '0.135', 'Skeletal myocytes': '0.107', 'Smooth muscle cells': '5.8', 'Adipocytes': '2.1', 'Melanocytes': '0.335', 'Fibroblasts': '6.5', 'Peritubular cells': '0.210', 'Endometrial stromal cells': '27.7', 'Ovarian stromal cells': '0.7', 'Undifferentiated cells': '101.6', 'T-cells': '2.9', 'B-cells': '4.4', 'Plasma cells': '6.1', 'Nk-cells': '0.0', 'Granulocytes': '8.4', 'Monocytes': '0.0', 'Macrophages': '6.0', 'Hofbauer cells': '4.3', 'Kupffer cells': '1.0', 'Dendritic cells': '5.9', 'Langerhans cells': '0.304', 'Erythroid cells': '0.036', 'Adipocytes (Subcutaneous)': '-0.081', 'Adipocytes (Visceral)': '-0.209', 'Breast glandular cells (progenitors)': '0.538', 'Adipocytes (Breast)': '-0.689', 'Colon enterocytes': '0.790', 'Colon enteroendocrine cells': '0.112', 'Enteric glia cells': '-0.048', 'Mitotic cells (Colon)': '0.299', 'Mitotic cells (Heart)': '0.120', 'Podocytes': '-0.118', 'Ascending Loop of Henle cells': '0.475', 'Intercalated cells': '0.212', 'Cholangiocyte': '0.090', 'NK-cells (Liver)': '-0.005', 'Respiratory ciliated cells': '-0.012', 'Mitotic cells (Lung)': '0.071', 'NK-cells (Lung)': '-0.266', 'B-cells (Lung)': '-0.296', 'Alpha cells': '0.270', 'Beta cells': '0.152', 'Prostate glandular cells': '0.764', 'Prostate basal glandular cells': '0.540', 'Urothelial cells': '0.205', 'Keratinocyte (other)': '0.510', 'Keratinocyte (granular)': '0.055', 'Hair cortex cells': '0.080', 'Inner root sheath cells': '0.131', 'Outer root sheath cells': '0.175', 'Sebaceous gland cells': '0.156', 'Eccrine sweat gland cells': '-0.207', 'Adipocytes (Skin)': '-0.244', 'Mitotic cells (Skin)': '0.442', 'Parietal cells': '0.654', 'Chief cells': '0.649', 'Gastric mucous cells': '0.781', 'Gastric enteroendocrine cells': '0.590', 'Mitotic cells (Stomach)': '0.445', 'Parafollicular cells': '0.173', 'Thyroid glandular cells': '0.865', 'Mitotic cells (Thyroid)': '-0.081', 'Adrenal cortex cells': '0.051', 'Adrenal medulla cells': '0.087', 'Mitotic cells (Adrenal gland)': '0.072', 'Minor salivary glandular cells': '0.371', 'Minor salivary gland ductal cells': '-0.142', 'Minor salivary gland basal cells': '0.582', 'Mitotic cells (Minor salivary gland)': '0.567', 'Adipocytes (Minor salivary gland)': '0.050', 'Somatotropes': '0.121', 'Lactotropes': '0.322', 'Gonadotropes': '0.330', 'Corticotropes': '0.180', 'Thyrotropes': '0.496', 'Undifferentiated cells (Pituitary gland)': '-0.108', 'Mitotic cells (Spleen)': '-0.228', 'Platelets': '-0.050', 'Erythrocytes': '-0.158', 'Hematopoietic stem cells': '-0.211', 'B-cells (Spleen)': '0.266', 'NK-cells (Spleen)': '0.309', 'Amygdala excitatory': '1.0', 'Cerebellar inhibitory': '0.9', 'Cge interneuron': '0.7', 'Deep-layer corticothalamic and 6b': '1.5', 'Deep-layer intratelencephalic': '0.7', 'Deep-layer near-projecting': '0.7', 'Eccentric medium spiny neuron': '0.6', 'Hippocampal ca1-3': '1.9', 'Hippocampal ca4': '1.2', 'Hippocampal dentate gyrus': '1.1', 'Lamp5-lhx6 and chandelier': '0.5', 'Lower rhombic lip': '0.8', 'Mammillary body': '0.6', 'Medium spiny neuron': '0.7', 'Mge interneuron': '1.7', 'Midbrain-derived inhibitory': '0.7', 'Miscellaneous': '0.9', 'Splatter': '3.8', 'Thalamic excitatory': '0.5', 'Upper rhombic lip': '0.8', 'Upper-layer intratelencephalic': '0.6', 'Astrocyte': '4.4', 'Bergmann glia': '0.2', 'Central nervous system macrophage': '0.6', 'Choroid plexus epithelial cell': '52.1', 'Committed oligodendrocyte precursor': '41.5', 'Ependymal cell': '4.8', 'Oligodendrocyte': '53.1', 'Oligodendrocyte precursor cell': '2.4', 'Endothelial cell': '0.7', 'Pericyte': '0.3', 'Vascular associated smooth muscle cell': '0.0', 'Fibroblast': '17.4', 'Leukocyte': '1.1', 'Basophil': '0.0', 'Eosinophil': '0.0', 'Neutrophil': '0.0', 'Classical monocyte': '0.0', 'Non-classical monocyte': '0.0', 'Intermediate monocyte': '0.0', 'T-reg': '2.3', 'GdT-cell': '0.0', 'MAIT T-cell': '0.0', 'Memory CD4 T-cell': '0.0', 'Naive CD4 T-cell': '0.1', 'Memory CD8 T-cell': '0.2', 'Naive CD8 T-cell': '0.3', 'Memory B-cell': '0.0', 'Naive B-cell': '0.1', 'Plasmacytoid DC': '46.6', 'Myeloid DC': '8.5', 'NK-cell': '0.1', 'Total PBMC': '0.7', 'Vd2 gdTCR': '0.0', 'Memory CD4 T-cell Th1\\/Th17': '0.1', 'Memory CD4 T-cell Th17': '0.2', 'Memory CD4 T-cell Th2': '2.9', 'Non-Vd2 gdTCR': '0.1', 'Memory CD4 T-cell Th1': '0.3', 'Memory CD4 T-cell TFH': '0.5', 'Terminal effector memory CD4 T-cell': '0.0', 'Central memory CD8 T-cell': '4.8', 'Effector memory CD8 T-cell': '0.0', 'Terminal effector memory CD8 T-cell': '0.6', 'Non-switched memory B-cell': '0.0', 'Plasmablast': '3.3', 'Switched memory B-cell': '0.0', 'Exhausted memory B-cell': '0.7', 'Progenitor cell': '2.3', 'Memory T-reg': '1.3', 'Naive CD4 T-cell activated': '0.3', 'Naive CD8 T-cell activated': '0.6', 'Naive T-reg': '0.1'}
1O6S, 2O72, 2OMT, 2OMU, 2OMV, 2OMX, 2OMY, 2OMZ, 3FF7, 3FF8, 3L6X, 3L6Y, 4ZT1, 4ZTE, 6CXY, 6OLE, 6OLF, 6OLG, 6VEL, 7STZ, 8H62
{'Adipose Tissue': 1.2125261088039867, 'Adrenal Gland': 0.1914223992248062, 'Bladder': 39.2033519047619, 'Blood': 1.340954264800861, 'Blood Vessel': 0.3121561692883895, 'Brain': 0.8550442199091597, 'Breast': 38.54918344226579, 'Cervix Uteri': 23.539115789473684, 'Colon': 43.41292142490372, 'Esophagus': 53.97513367404844, 'Fallopian Tube': 14.900277777777776, 'Heart': 0.119140469221835, 'Kidney': 25.040449438202245, 'Liver': 26.60802654867257, 'Lung': 35.447986366782004, 'Muscle': 0.1378936151930261, 'Nerve': 17.518468982229404, 'Ovary': 3.6515122222222223, 'Pancreas': 56.89676829268293, 'Pituitary': 24.68741660777385, 'Prostate': 61.279967346938776, 'Salivary Gland': 92.01685185185184, 'Skin': 79.77571720232172, 'Small Intestine': 71.7519320855615, 'Spleen': 10.061029045643156, 'Stomach': 58.07813805013927, 'Testis': 0.8144204986149585, 'Thyroid': 135.176797856049, 'Uterus': 1.442593943661972, 'Vagina': 86.52345512820513}
TEX14
MSRAVRLPVPCPVQLGTLRNDSLEAQLHEYVKQGNYVKVKKILKKGIYVDAVNSLGQTALFVAALLGLRKFVDVLVDYGSDPNHRCFDGSTPVHAAAFSGNQWILSKLLDAGGDLRLHDERGQNPKTWALTAGKERSTQIVEFMQRCASHMQAIIQGFSYDLLKKIDSPQRLVYSPSWCGGLVQGNPNGSPNRLLKAGVISAQNIYSFGFGKFYLTGATQMAYLGSLPVIGEKEVIQADDEPTFSFFSGPYMVMTNLVWNGSRVTVKELNLPTHPHCSRLRLADLLIAEQEHSSKLRHPYLLQLMAVCLSQDLEKTRLVYERITIGTLFSVLHERRSQFPVLHMEVIVHLLLQISDALRYLHFQGFIHRSLSSYAVHIISPGEARLTNLEYMLESEDRGVQRDLTRVPLPTQLYNWAAPEVILQKAATVKSDIYSFSMIMQEILTDDIPWKGLDGSVVKKAVVSGNYLEADVRLPKPYYDIVKSGIHVKQKDRTMNLQDIRYILKNDLKDFTGAQRTQPTESPRVQRYGLHPDVNVYLGLTSEHPRETPDMEIIELKEMGSQPHSPRVHSLFTEGTLDPQAPDPCLMARETQNQDAPCPAPFMAEEASSPSTGQPSLCSFEINEIYSGCLILEDDIEEPPGAASSLEADGPNQVDELKSMEEELDKMEREACCFGSEDESSSKAETEYSFDDWDWQNGSLSSLSLPESTREAKSNLNNMSTTEEYLISKCVLDLKIMQTIMHENDDRLRNIEQILDEVEMKQKEQEERMSLWATSREFTNAYKLPLAVGPPSLNYIPPVLQLSGGQKPDTSGNYPTLPRFPRMLPTLCDPGKQNTDEQFQCTQGAKDSLETSRIQNTSSQGRPRESTAQAKATQFNSALFTLSSHRQGPSASPSCHWDSTRMSVEPVSSEIYNAESRNKDDGKVHLKWKMEVKEMAKKAATGQLTVPPWHPQSSLTLESEAENEPDALLQPPIRSPENTDWQRVIEYHRENDEPRGNGKFDKTGNNDCDSDQHGRQPRLGSFTSIRHPSPRQKEQPEHSEAFQASSDTLVAVEKSYSTSSPIEEDFEGIQGAFAQPQVSGEEKFQMRKILGKNAEILPRSQFQPVRSTEDEQEETSKESPKELKEKDISLTDIQDLSSISYEPDSSFKEASCKTPKINHAPTSVSTPLSPGSVSSAASQYKDCLESITFQVKTEFASCWNSQEFIQTLSDDFISVRERAKKLDSLLTSSETPPSRLTGLKRLSSFIGAGSPSLVKACDSSPPHATQRRSLPKVEAFSQHHIDELPPPSQELLDDIELLKQQQGSSTVLHENTASDGGGTANDQRHLEEQETDSKKEDSSMLLSKETEDLGEDTERAHSTLDEDLERWLQPPEESVELQDLPKGSERETNIKDQKVGEEKRKREDSITPERRKSEGVLGTSEEDELKSCFWKRLGWSESSRIIVLDQSDLSD
Homo sapiens
null
Not found
{}
null
{'Adipose Tissue': 0.3145132392026578, 'Adrenal Gland': 0.3133024031007752, 'Bladder': 0.2332080952380952, 'Blood': 0.1484838191603875, 'Blood Vessel': 0.3190282247191011, 'Brain': 0.6371041559424678, 'Breast': 0.5415899782135076, 'Cervix Uteri': 0.4543, 'Colon': 0.3571990757381258, 'Esophagus': 0.2190303564013841, 'Fallopian Tube': 0.5987555555555555, 'Heart': 0.1271113577235772, 'Kidney': 0.1459244943820224, 'Liver': 0.2177287168141593, 'Lung': 0.7923321799307959, 'Muscle': 0.0888587895392278, 'Nerve': 0.4798468012924071, 'Ovary': 0.7997588888888889, 'Pancreas': 0.1199840548780488, 'Pituitary': 0.5444271024734982, 'Prostate': 0.7214534693877551, 'Salivary Gland': 0.2831964197530864, 'Skin': 0.7787533316749586, 'Small Intestine': 0.3033267379679144, 'Spleen': 0.6581099585062241, 'Stomach': 0.3113348467966574, 'Testis': 40.536603878116345, 'Thyroid': 0.2045333996937212, 'Uterus': 0.5003197887323944, 'Vagina': 0.2421473717948718}
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73.27, 70.36, 72.63, 72.69, 68.11, 66.06, 60.67, 52.64, 44.07, 48.46, 43.79, 36.31]
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0.54, 0.27, 0.29, 0.51, 0.08, 0.77, 0.06, 0.62, 0.39, 0.34, 0.94, 0.83, 0.46, 0.51, 0.07, 0.17, 0.07, 0.41, 0.14, 0.31, 0.2, 0.36, 0.0, 0.13, 0.59, 0.53, 0.77, 0.2, 0.64, 0.35, 0.0, 0.02, 0.39, 0.18, 0.39, 0.57, 0.63, 0.39, 0.0, 0.32, 0.0, 0.18, 0.03, 0.29, 0.47, 0.55, 0.03, 0.34, 0.2, 0.45, 0.56, 0.17, 0.37, 0.59, 0.01, 0.39, 0.0, 0.39, 0.05, 0.28, 0.07, 0.29, 0.26, 0.64, 0.82, 0.64, 0.63, 0.76, 0.15, 0.39, 0.95, 0.57, 0.28, 0.58, 0.02, 0.43, 0.0, 0.29, 0.09, 0.4, 0.13, 0.49, 0.31, 0.53, 0.32, 0.66, 0.01, 0.71, 0.13, 0.56, 0.54, 0.84, 0.51, 0.06, 0.82, 0.14, 0.54, 0.07, 0.63, 0.05, 0.7, 0.17, 0.75, 0.51, 0.64, 0.36, 0.67, 0.15, 0.12, 0.61, 0.0, 0.33, 0.14, 0.62, 0.2, 0.52, 0.05, 0.14, 0.63, 0.95, 0.85, 0.32, 0.6, 0.1, 0.12, 0.17, 0.17, 0.06, 0.08, 0.41, 0.28, 0.55, 0.49, 0.09, 0.68, 0.23, 0.53, 0.64, 0.52, 0.42, 0.64, 0.64, 0.0, 0.08, 0.44, 0.13, 0.48, 0.52, 0.81, 0.44, 0.0, 0.26, 0.0, 0.21, 0.03, 0.46, 0.27, 0.71, 0.45, 0.06, 0.28, 0.28, 0.4, 0.65, 0.28, 0.46, 0.61, 0.0, 0.36, 0.0, 0.32, 0.01, 0.22, 0.0, 0.05, 0.0, 0.41, 0.46, 0.42, 0.82, 0.48, 0.4, 0.5, 0.17, 0.62, 0.06, 0.32, 0.0, 0.25, 0.0, 0.42, 0.08, 0.41, 0.27, 0.16, 0.04, 0.36, 0.32, 0.2, 0.0, 0.52, 0.04, 0.66, 0.47, 0.52, 0.78, 0.09, 0.77, 0.08, 0.6, 0.0, 0.31, 0.03, 0.58, 0.47, 0.59, 0.44, 0.23, 0.54, 0.1, 0.18, 0.45, 0.0, 0.53, 0.11, 0.59, 0.17, 0.51, 0.01, 0.19, 0.71, 0.77, 0.3, 0.44, 0.08, 0.14, 0.52, 0.05, 0.37, 0.1, 0.42, 0.23, 0.61, 0.43, 0.22, 0.96, 0.54, 0.4, 0.3, 0.07, 0.39, 0.17, 0.43, 0.38, 0.3, 0.8, 0.83, 0.44, 0.03, 0.11, 0.0, 0.23, 0.0, 0.31, 0.0, 0.38, 0.58, 0.51, 0.01, 0.49, 0.13, 0.26, 0.69, 0.46, 0.41, 0.51, 0.06, 0.51, 0.03, 0.38, 0.0, 0.06, 0.0, 0.34, 0.08, 0.53, 0.42, 0.88, 0.25, 0.75, 0.49, 1.0, 0.34, 0.86, 0.48, 0.18, 0.52, 0.01, 0.32, 0.0, 0.19, 0.0, 0.3, 0.05, 0.44, 0.27, 0.43, 0.11, 0.31, 0.39, 0.03, 0.55, 0.04, 0.52, 0.51, 0.64, 0.57, 0.19, 0.68, 0.13, 0.84, 0.06, 0.31, 0.07, 0.69, 0.26, 0.37, 0.53, 0.67, 0.5, 0.56, 0.14, 0.18, 0.47, 0.01, 0.47, 0.15, 0.61, 0.28, 0.2, 0.02, 0.76, 0.55, 0.31, 0.94, 0.22, 0.57, 0.17, 0.4, 0.07, 0.5, 0.31, 0.7, 0.2, 0.14, 0.3, 0.23, 0.58, 0.07, 0.06, 0.55, 0.15, 0.46, 0.43, 0.64, 0.53, 0.0, 0.18, 0.01, 0.23, 0.02, 0.63, 0.33, 0.79, 0.06, 0.38, 0.07, 0.14, 0.23, 0.68, 0.89, 0.29, 0.06, 0.72, 0.92, 0.24, 0.25, 0.0, 0.46, 0.02, 0.21, 0.01, 0.06, 0.0, 0.05, 0.07, 0.61, 0.17, 0.89, 0.72, 0.66, 0.14, 0.52, 0.07, 0.58, 0.01, 0.26, 0.0, 0.13, 0.0, 0.29, 0.04, 0.46, 0.27, 0.28, 0.23, 0.56, 0.32, 0.25, 0.0, 0.33, 0.05, 0.55, 0.5, 0.58, 0.53, 0.04, 0.27, 0.02, 0.04, 0.37, 0.67, 0.74, 0.35, 0.62, 0.54, 0.26, 0.46, 0.0, 0.47, 0.09, 0.45, 0.15, 0.39, 0.05, 0.44, 0.85, 0.56, 0.11, 0.11, 0.35, 0.42, 0.03, 0.32, 0.12, 0.49, 0.19, 0.25, 0.8, 0.6, 0.09, 0.49, 0.57, 0.36, 0.04, 0.35, 0.28, 0.52, 0.39, 0.5, 0.28, 0.93, 0.47, 0.3, 0.47, 0.08, 0.02, 0.18, 0.01, 0.34, 0.23, 0.55, 0.57, 0.91, 0.1, 0.78, 0.52, 0.34, 0.61, 0.24, 0.75, 0.0, 0.2, 0.02, 0.24, 0.0, 0.18, 0.04, 0.44, 0.59, 0.71, 0.29, 0.52, 0.37, 0.5, 0.11, 0.6, 0.02, 0.48, 0.01, 0.16, 0.04, 0.35, 0.66, 0.47, 0.74, 0.14, 0.62, 0.16, 0.77, 0.79, 0.27, 0.93, 0.69, 0.88, 0.88, 0.85, 0.87, 0.91, 0.92, 0.82, 0.63, 0.75, 0.7, 0.7, 0.38, 0.43, 0.64, 0.55, 0.54, 0.59, 0.45, 0.47, 0.5, 0.58, 0.52, 0.61, 0.57, 0.52, 0.68, 0.44, 0.6, 0.61, 0.58, 0.55, 0.5, 0.61, 0.61, 0.86, 0.86, 0.75, 0.91, 0.96, 0.93, 1.0, 0.87, 0.97, 0.91, 0.95, 0.86, 0.98, 0.93, 0.88, 0.59, 0.87, 0.7, 0.67, 0.85, 0.89, 0.88, 0.91, 0.93, 0.88, 0.99, 0.92, 1.0, 0.79, 0.9, 1.0, 0.94, 1.0, 0.97, 0.96, 0.9, 0.63, 0.68, 0.48, 0.54, 0.8, 0.7, 0.7, 0.95, 0.87, 0.77, 0.84, 0.79, 0.89, 0.95, 0.8, 0.77, 0.51, 0.87, 0.7, 0.52, 0.84, 0.91, 0.51, 0.96, 0.79, 0.92, 0.84, 0.21, 0.89, 0.53, 0.52, 0.89, 0.86, 0.26, 0.91, 0.45, 0.68, 0.84, 0.48, 0.44, 0.51, 0.62, 0.28, 0.59, 0.63, 0.57, 0.15, 0.55, 0.66, 0.1, 0.38, 0.74, 0.65, 0.17, 0.43, 0.66, 0.41, 0.8, 0.75, 0.9, 0.93, 0.52, 0.76, 0.89, 0.87, 0.76, 0.92, 0.91, 0.75, 0.61, 0.96, 0.89, 0.73, 0.97, 0.68, 0.87, 0.55, 0.85, 0.77, 0.69, 0.76, 0.98, 0.83, 0.68, 0.82, 0.74, 0.65, 0.96, 0.93, 0.54, 0.64, 0.28, 0.54, 0.52, 0.16, 0.51, 0.88, 0.6, 0.4, 0.88, 0.95, 0.33, 0.56, 0.73, 0.39, 0.06, 0.61, 0.75, 0.47, 0.19, 0.87, 0.7, 0.97, 0.94, 0.97]
null
null
null
Component of an E-cadherin/ catenin adhesion complex composed of at least E-cadherin/CDH1, beta-catenin/CTNNB1 or gamma-catenin/JUP, and potentially alpha-catenin/CTNNA1. Forms a ternary complex composed of ADAM10, CADH1 and EPHA4,
null
null
KLRG1, SPEF1, DLGAP5, AJAP1, RAPGEF2, RAB8B, PIP5K1C, PKP2, TRPV4, CTNNB1, CAV1, DDR1, TBC1D2, CTNNA1, JUP, CTNND1, PSEN1, LIMA1, CDH1, JUP, ADAM10, CADH1 , EPHA4,
null
null
null
null
Homodimer
null
79.91949
0.474025
null
null
212
P12830
Q8IWF2
null
degron_data
CDH1
MGPWSRSLSALLLLLQVSSWLCQEPEPCHPGFDAESYTFTVPRRHLERGRVLGRVNFEDCTGRQRTAYFSLDTRFKVGTDGVITVKRPLRFHNPQIHFLVYAWDSTYRKFSTKVTLNTVGHHHRPPPHQASVSGIQAELLTFPNSSPGLRRQKRDWVIPPISCPENEKGPFPKNLVQIKSNKDKEGKVFYSITGQGADTPPVGVFIIERETGWLKVTEPLDRERIATYTLFSHAVSSNGNAVEDPMEILITVTDQNDNKPEFTQEVFKGSVMEGALPGTSVMEVTATDADDDVNTYNAAIAYTILSQDPELPDKNMFTINRNTGVISVVTTGLDRESFPTYTLVVQAADLQGEGLSTTATAVITVTDTNDNPPIFNPTTYKGQVPENEANVVITTLKVTDADAPNTPAWEAVYTILNDDGGQFVVTTNPVNNDGILKTAKGLDFEAKQQYILHVAVTNVVPFEVSLTTSTATVTVDVLDVNEAPIFVPPEKRVEVSEDFGVGQEITSYTAQEPDTFMEQKITYRIWRDTANWLEINPDTGAISTRAELDREDFEHVKNSTYTALIIATDNGSPVATGTGTLLLILSDVNDNAPIPEPRTIFFCERNPKPQVINIIDADLPPNTSPFTAELTHGASANWTIQYNDPTQESIILKPKMALEVGDYKINLKLMDNQNKDQVTTLEVSVCDCEGAAGVCRKAQPVEAGLQIPAILGILGGILALLILILLLLLFLRRRAVVKEPLLPPEDDTRDNVYYYDEEGGGEEDQDFDLSQLHRGLDARPEVTRNDVAPTLMSVPRYLPRPANPDEIGNFIDENLKAADTDPTAPPYDSLLVFDYEGSGSEAASLSSLNSSESDKDQDYDYLNEWGNRFKKLADMYGGGEDD
Homo sapiens
Cell junction, adherens junction, Cell membrane, Endosome, Golgi apparatus, trans-Golgi network, Cytoplasm, Cell junction, desmosome
Tissue enhanced (parathyroid)
{'Ciliated cells': '119.1', 'Basal respiratory cells': '71.1', 'Club cells': '97.3', 'Ionocytes': '81.0', 'Mucus glandular cells': '155.0', 'Serous glandular cells': '67.8', 'Gastric mucus-secreting cells': '133.2', 'Proximal enterocytes': '140.9', 'Paneth cells': '125.1', 'Distal enterocytes': '307.5', 'Intestinal goblet cells': '173.5', 'Exocrine glandular cells': '-0.605', 'Basal prostatic cells': '68.3', 'Prostatic glandular cells': '186.7', 'Breast glandular cells': '0.773', 'Breast myoepithelial cells': '0.700', 'Glandular and luminal cells': '313.0', 'Secretory cells': '82.3', 'Basal keratinocytes': '102.5', 'Suprabasal keratinocytes': '162.6', 'Basal squamous epithelial cells': '51.0', 'Squamous epithelial cells': '106.9', 'Alveolar cells type 1': '0.437', 'Alveolar cells type 2': '0.706', 'Salivary duct cells': '95.9', 'Ductal cells': '0.541', 'Hepatocytes': '0.600', 'Cholangiocytes': '129.7', 'Proximal tubular cells': '0.042', 'Distal tubular cells': '0.0', 'Collecting duct cells': '143.9', 'Mesothelial cells': '0.799', 'Sertoli cells': '0.252', 'Granulosa cells': '12.9', 'Enteroendocrine cells': '92.4', 'Pancreatic endocrine cells': '78.1', 'Leydig cells': '0.264', 'Excitatory neurons': '0.7', 'Inhibitory neurons': '1.3', 'Cone photoreceptor cells': '0.0', 'Rod photoreceptor cells': '0.0', 'Bipolar cells': '0.2', 'Horizontal cells': '0.6', 'Astrocytes': '0.6', 'Oligodendrocyte precursor cells': '0.5', 'Oligodendrocytes': '29.9', 'Microglial cells': '0.9', 'Muller glia cells': '0.1', 'Schwann cells': '0.131', 'Spermatogonia': '0.392', 'Spermatocytes': '0.193', 'Early spermatids': '-0.217', 'Late spermatids': '-0.290', 'Oocytes': '16.9', 'Cytotrophoblasts': '119.2', 'Syncytiotrophoblasts': '45.0', 'Extravillous trophoblasts': '24.9', 'Endothelial cells': '6.1', 'Lymphatic endothelial cells': '0.4', 'Cardiomyocytes': '0.135', 'Skeletal myocytes': '0.107', 'Smooth muscle cells': '5.8', 'Adipocytes': '2.1', 'Melanocytes': '0.335', 'Fibroblasts': '6.5', 'Peritubular cells': '0.210', 'Endometrial stromal cells': '27.7', 'Ovarian stromal cells': '0.7', 'Undifferentiated cells': '101.6', 'T-cells': '2.9', 'B-cells': '4.4', 'Plasma cells': '6.1', 'Nk-cells': '0.0', 'Granulocytes': '8.4', 'Monocytes': '0.0', 'Macrophages': '6.0', 'Hofbauer cells': '4.3', 'Kupffer cells': '1.0', 'Dendritic cells': '5.9', 'Langerhans cells': '0.304', 'Erythroid cells': '0.036', 'Adipocytes (Subcutaneous)': '-0.081', 'Adipocytes (Visceral)': '-0.209', 'Breast glandular cells (progenitors)': '0.538', 'Adipocytes (Breast)': '-0.689', 'Colon enterocytes': '0.790', 'Colon enteroendocrine cells': '0.112', 'Enteric glia cells': '-0.048', 'Mitotic cells (Colon)': '0.299', 'Mitotic cells (Heart)': '0.120', 'Podocytes': '-0.118', 'Ascending Loop of Henle cells': '0.475', 'Intercalated cells': '0.212', 'Cholangiocyte': '0.090', 'NK-cells (Liver)': '-0.005', 'Respiratory ciliated cells': '-0.012', 'Mitotic cells (Lung)': '0.071', 'NK-cells (Lung)': '-0.266', 'B-cells (Lung)': '-0.296', 'Alpha cells': '0.270', 'Beta cells': '0.152', 'Prostate glandular cells': '0.764', 'Prostate basal glandular cells': '0.540', 'Urothelial cells': '0.205', 'Keratinocyte (other)': '0.510', 'Keratinocyte (granular)': '0.055', 'Hair cortex cells': '0.080', 'Inner root sheath cells': '0.131', 'Outer root sheath cells': '0.175', 'Sebaceous gland cells': '0.156', 'Eccrine sweat gland cells': '-0.207', 'Adipocytes (Skin)': '-0.244', 'Mitotic cells (Skin)': '0.442', 'Parietal cells': '0.654', 'Chief cells': '0.649', 'Gastric mucous cells': '0.781', 'Gastric enteroendocrine cells': '0.590', 'Mitotic cells (Stomach)': '0.445', 'Parafollicular cells': '0.173', 'Thyroid glandular cells': '0.865', 'Mitotic cells (Thyroid)': '-0.081', 'Adrenal cortex cells': '0.051', 'Adrenal medulla cells': '0.087', 'Mitotic cells (Adrenal gland)': '0.072', 'Minor salivary glandular cells': '0.371', 'Minor salivary gland ductal cells': '-0.142', 'Minor salivary gland basal cells': '0.582', 'Mitotic cells (Minor salivary gland)': '0.567', 'Adipocytes (Minor salivary gland)': '0.050', 'Somatotropes': '0.121', 'Lactotropes': '0.322', 'Gonadotropes': '0.330', 'Corticotropes': '0.180', 'Thyrotropes': '0.496', 'Undifferentiated cells (Pituitary gland)': '-0.108', 'Mitotic cells (Spleen)': '-0.228', 'Platelets': '-0.050', 'Erythrocytes': '-0.158', 'Hematopoietic stem cells': '-0.211', 'B-cells (Spleen)': '0.266', 'NK-cells (Spleen)': '0.309', 'Amygdala excitatory': '1.0', 'Cerebellar inhibitory': '0.9', 'Cge interneuron': '0.7', 'Deep-layer corticothalamic and 6b': '1.5', 'Deep-layer intratelencephalic': '0.7', 'Deep-layer near-projecting': '0.7', 'Eccentric medium spiny neuron': '0.6', 'Hippocampal ca1-3': '1.9', 'Hippocampal ca4': '1.2', 'Hippocampal dentate gyrus': '1.1', 'Lamp5-lhx6 and chandelier': '0.5', 'Lower rhombic lip': '0.8', 'Mammillary body': '0.6', 'Medium spiny neuron': '0.7', 'Mge interneuron': '1.7', 'Midbrain-derived inhibitory': '0.7', 'Miscellaneous': '0.9', 'Splatter': '3.8', 'Thalamic excitatory': '0.5', 'Upper rhombic lip': '0.8', 'Upper-layer intratelencephalic': '0.6', 'Astrocyte': '4.4', 'Bergmann glia': '0.2', 'Central nervous system macrophage': '0.6', 'Choroid plexus epithelial cell': '52.1', 'Committed oligodendrocyte precursor': '41.5', 'Ependymal cell': '4.8', 'Oligodendrocyte': '53.1', 'Oligodendrocyte precursor cell': '2.4', 'Endothelial cell': '0.7', 'Pericyte': '0.3', 'Vascular associated smooth muscle cell': '0.0', 'Fibroblast': '17.4', 'Leukocyte': '1.1', 'Basophil': '0.0', 'Eosinophil': '0.0', 'Neutrophil': '0.0', 'Classical monocyte': '0.0', 'Non-classical monocyte': '0.0', 'Intermediate monocyte': '0.0', 'T-reg': '2.3', 'GdT-cell': '0.0', 'MAIT T-cell': '0.0', 'Memory CD4 T-cell': '0.0', 'Naive CD4 T-cell': '0.1', 'Memory CD8 T-cell': '0.2', 'Naive CD8 T-cell': '0.3', 'Memory B-cell': '0.0', 'Naive B-cell': '0.1', 'Plasmacytoid DC': '46.6', 'Myeloid DC': '8.5', 'NK-cell': '0.1', 'Total PBMC': '0.7', 'Vd2 gdTCR': '0.0', 'Memory CD4 T-cell Th1\\/Th17': '0.1', 'Memory CD4 T-cell Th17': '0.2', 'Memory CD4 T-cell Th2': '2.9', 'Non-Vd2 gdTCR': '0.1', 'Memory CD4 T-cell Th1': '0.3', 'Memory CD4 T-cell TFH': '0.5', 'Terminal effector memory CD4 T-cell': '0.0', 'Central memory CD8 T-cell': '4.8', 'Effector memory CD8 T-cell': '0.0', 'Terminal effector memory CD8 T-cell': '0.6', 'Non-switched memory B-cell': '0.0', 'Plasmablast': '3.3', 'Switched memory B-cell': '0.0', 'Exhausted memory B-cell': '0.7', 'Progenitor cell': '2.3', 'Memory T-reg': '1.3', 'Naive CD4 T-cell activated': '0.3', 'Naive CD8 T-cell activated': '0.6', 'Naive T-reg': '0.1'}
1O6S, 2O72, 2OMT, 2OMU, 2OMV, 2OMX, 2OMY, 2OMZ, 3FF7, 3FF8, 3L6X, 3L6Y, 4ZT1, 4ZTE, 6CXY, 6OLE, 6OLF, 6OLG, 6VEL, 7STZ, 8H62
{'Adipose Tissue': 1.2125261088039867, 'Adrenal Gland': 0.1914223992248062, 'Bladder': 39.2033519047619, 'Blood': 1.340954264800861, 'Blood Vessel': 0.3121561692883895, 'Brain': 0.8550442199091597, 'Breast': 38.54918344226579, 'Cervix Uteri': 23.539115789473684, 'Colon': 43.41292142490372, 'Esophagus': 53.97513367404844, 'Fallopian Tube': 14.900277777777776, 'Heart': 0.119140469221835, 'Kidney': 25.040449438202245, 'Liver': 26.60802654867257, 'Lung': 35.447986366782004, 'Muscle': 0.1378936151930261, 'Nerve': 17.518468982229404, 'Ovary': 3.6515122222222223, 'Pancreas': 56.89676829268293, 'Pituitary': 24.68741660777385, 'Prostate': 61.279967346938776, 'Salivary Gland': 92.01685185185184, 'Skin': 79.77571720232172, 'Small Intestine': 71.7519320855615, 'Spleen': 10.061029045643156, 'Stomach': 58.07813805013927, 'Testis': 0.8144204986149585, 'Thyroid': 135.176797856049, 'Uterus': 1.442593943661972, 'Vagina': 86.52345512820513}
FOXRED2
MGLSAAAPLWGPPGLLLAIALHPALSVPPRRDYCVLGAGPAGLQMAYFLQRAGRDYAVFERAPRPGSFFTRYPRHRKLISINKRYTGKANAEFNLRHDWNSLLSHDPRLLFRHYSRAYFPDARDMVRYLGDFADTLGLRVQYNTTIAHVTLDKDRQAWNGHYFILTDQKGQVHQCSVLFVATGLSVPNQVDFPGSEYAEGYESVSVDPEDFVGQNVLILGRGNSAFETAENILGVTNFIHMLSRSRVRLSWATHYVGDLRAINNGLLDTYQLKSLDGLLESDLTDLAILKDSKGKFHVTPKFFLEEANTNQSADSITLPQDDNDNFAMRVPYDRVIRCLGWNFDFSIFNKSLRLNSGNAFGKKYPLIRASYESKGSRGLFILGTASHSVDYRKSAGGFIHGFRYTVRAVHRLLEHRHHSVTWPATELPITQLTSSIVRRVNEASGLYQMFGVLADVILLKENSTAFEYLEEFPIQMLAQLETLTGRKAKHGLFVINMEYGRNFSGPDKDVFFDDRSVGHTEDAWQSNFLHPVIYYYRYLPTEQEVRFRPAHWPLPRPTAIHHIVEDFLTDWTAPIGHILPLRRFLENCLDTDLRSFYAESCFLFALTRQKLPPFCQQGYLRMQGLVSTESLWQHRVESRLLRDYAPTGRRLEDSSQQLGDQEPLGSPLAPGPLAQSVDSNKEEL
Homo sapiens
Endoplasmic reticulum lumen
Low tissue specificity
{'Ciliated cells': '1.2', 'Basal respiratory cells': '0.9', 'Club cells': '3.6', 'Ionocytes': '1.5', 'Mucus glandular cells': '7.0', 'Serous glandular cells': '5.9', 'Gastric mucus-secreting cells': '0.6', 'Proximal enterocytes': '0.3', 'Paneth cells': '1.4', 'Distal enterocytes': '0.3', 'Intestinal goblet cells': '1.3', 'Exocrine glandular cells': '-0.009', 'Basal prostatic cells': '3.1', 'Prostatic glandular cells': '11.4', 'Breast glandular cells': '0.439', 'Breast myoepithelial cells': '0.396', 'Glandular and luminal cells': '3.7', 'Secretory cells': '2.3', 'Basal keratinocytes': '4.8', 'Suprabasal keratinocytes': '3.7', 'Basal squamous epithelial cells': '4.2', 'Squamous epithelial cells': '4.5', 'Alveolar cells type 1': '-0.096', 'Alveolar cells type 2': '0.207', 'Salivary duct cells': '4.5', 'Ductal cells': '0.158', 'Hepatocytes': '0.572', 'Cholangiocytes': '3.8', 'Proximal tubular cells': '0.384', 'Distal tubular cells': '0.0', 'Collecting duct cells': '3.9', 'Mesothelial cells': '0.424', 'Sertoli cells': '0.518', 'Granulosa cells': '5.5', 'Enteroendocrine cells': '0.3', 'Pancreatic endocrine cells': '0.0', 'Leydig cells': '0.518', 'Excitatory neurons': '3.4', 'Inhibitory neurons': '8.7', 'Cone photoreceptor cells': '3.4', 'Rod photoreceptor cells': '3.8', 'Bipolar cells': '9.7', 'Horizontal cells': '9.4', 'Astrocytes': '6.5', 'Oligodendrocyte precursor cells': '5.7', 'Oligodendrocytes': '5.1', 'Microglial cells': '0.0', 'Muller glia cells': '6.7', 'Schwann cells': '0.124', 'Spermatogonia': '0.749', 'Spermatocytes': '0.520', 'Early spermatids': '-0.334', 'Late spermatids': '-0.561', 'Oocytes': '8.1', 'Cytotrophoblasts': '11.0', 'Syncytiotrophoblasts': '3.3', 'Extravillous trophoblasts': '4.4', 'Endothelial cells': '2.1', 'Lymphatic endothelial cells': '0.7', 'Cardiomyocytes': '0.738', 'Skeletal myocytes': '0.014', 'Smooth muscle cells': '3.6', 'Adipocytes': '0.9', 'Melanocytes': '0.379', 'Fibroblasts': '6.9', 'Peritubular cells': '0.429', 'Endometrial stromal cells': '5.6', 'Ovarian stromal cells': '9.7', 'Undifferentiated cells': '4.0', 'T-cells': '1.0', 'B-cells': '1.7', 'Plasma cells': '3.8', 'Nk-cells': '0.8', 'Granulocytes': '1.4', 'Monocytes': '0.9', 'Macrophages': '6.0', 'Hofbauer cells': '9.4', 'Kupffer cells': '11.0', 'Dendritic cells': '8.8', 'Langerhans cells': '0.301', 'Erythroid cells': '-0.177', 'Adipocytes (Subcutaneous)': '-0.126', 'Adipocytes (Visceral)': '-0.133', 'Breast glandular cells (progenitors)': '0.542', 'Adipocytes (Breast)': '-0.324', 'Colon enterocytes': '-0.100', 'Colon enteroendocrine cells': '0.395', 'Enteric glia cells': '0.184', 'Mitotic cells (Colon)': '-0.166', 'Mitotic cells (Heart)': '0.366', 'Podocytes': '-0.127', 'Ascending Loop of Henle cells': '0.446', 'Intercalated cells': '0.097', 'Cholangiocyte': '0.119', 'NK-cells (Liver)': '-0.080', 'Respiratory ciliated cells': '-0.056', 'Mitotic cells (Lung)': '0.230', 'NK-cells (Lung)': '-0.164', 'B-cells (Lung)': '-0.180', 'Alpha cells': '0.250', 'Beta cells': '0.080', 'Prostate glandular cells': '0.349', 'Prostate basal glandular cells': '0.251', 'Urothelial cells': '0.050', 'Keratinocyte (other)': '0.309', 'Keratinocyte (granular)': '0.068', 'Hair cortex cells': '0.097', 'Inner root sheath cells': '0.154', 'Outer root sheath cells': '0.045', 'Sebaceous gland cells': '0.132', 'Eccrine sweat gland cells': '-0.118', 'Adipocytes (Skin)': '-0.004', 'Mitotic cells (Skin)': '0.395', 'Parietal cells': '-0.434', 'Chief cells': '-0.159', 'Gastric mucous cells': '-0.354', 'Gastric enteroendocrine cells': '-0.182', 'Mitotic cells (Stomach)': '0.054', 'Parafollicular cells': '0.107', 'Thyroid glandular cells': '0.501', 'Mitotic cells (Thyroid)': '0.017', 'Adrenal cortex cells': '0.652', 'Adrenal medulla cells': '0.032', 'Mitotic cells (Adrenal gland)': '0.336', 'Minor salivary glandular cells': '0.437', 'Minor salivary gland ductal cells': '0.118', 'Minor salivary gland basal cells': '-0.018', 'Mitotic cells (Minor salivary gland)': '0.219', 'Adipocytes (Minor salivary gland)': '-0.005', 'Somatotropes': '-0.109', 'Lactotropes': '0.021', 'Gonadotropes': '0.198', 'Corticotropes': '-0.065', 'Thyrotropes': '0.138', 'Undifferentiated cells (Pituitary gland)': '0.396', 'Mitotic cells (Spleen)': '0.163', 'Platelets': '0.280', 'Erythrocytes': '-0.084', 'Hematopoietic stem cells': '0.157', 'B-cells (Spleen)': '-0.150', 'NK-cells (Spleen)': '-0.001', 'Amygdala excitatory': '8.6', 'Cerebellar inhibitory': '12.5', 'Cge interneuron': '18.9', 'Deep-layer corticothalamic and 6b': '9.6', 'Deep-layer intratelencephalic': '9.2', 'Deep-layer near-projecting': '10.6', 'Eccentric medium spiny neuron': '8.8', 'Hippocampal ca1-3': '5.5', 'Hippocampal ca4': '3.0', 'Hippocampal dentate gyrus': '2.7', 'Lamp5-lhx6 and chandelier': '19.3', 'Lower rhombic lip': '2.9', 'Mammillary body': '3.4', 'Medium spiny neuron': '6.1', 'Mge interneuron': '9.3', 'Midbrain-derived inhibitory': '13.6', 'Miscellaneous': '6.7', 'Splatter': '7.5', 'Thalamic excitatory': '6.3', 'Upper rhombic lip': '7.6', 'Upper-layer intratelencephalic': '6.4', 'Astrocyte': '14.0', 'Bergmann glia': '7.7', 'Central nervous system macrophage': '3.7', 'Choroid plexus epithelial cell': '7.5', 'Committed oligodendrocyte precursor': '7.3', 'Ependymal cell': '9.0', 'Oligodendrocyte': '7.5', 'Oligodendrocyte precursor cell': '14.8', 'Endothelial cell': '1.6', 'Pericyte': '1.8', 'Vascular associated smooth muscle cell': '1.4', 'Fibroblast': '7.2', 'Leukocyte': '1.4', 'Basophil': '0.7', 'Eosinophil': '0.0', 'Neutrophil': '0.6', 'Classical monocyte': '2.8', 'Non-classical monocyte': '2.5', 'Intermediate monocyte': '4.7', 'T-reg': '2.4', 'GdT-cell': '0.2', 'MAIT T-cell': '1.9', 'Memory CD4 T-cell': '0.2', 'Naive CD4 T-cell': '3.2', 'Memory CD8 T-cell': '0.2', 'Naive CD8 T-cell': '3.7', 'Memory B-cell': '0.3', 'Naive B-cell': '1.8', 'Plasmacytoid DC': '22.5', 'Myeloid DC': '6.9', 'NK-cell': '2.0', 'Total PBMC': '2.8', 'Vd2 gdTCR': '1.5', 'Memory CD4 T-cell TFH': '2.0', 'Memory CD4 T-cell Th2': '1.7', 'Memory CD4 T-cell Th17': '1.4', 'Memory CD4 T-cell Th1\\/Th17': '1.2', 'Non-Vd2 gdTCR': '1.2', 'Memory CD4 T-cell Th1': '1.6', 'Terminal effector memory CD4 T-cell': '1.6', 'Central memory CD8 T-cell': '1.1', 'Effector memory CD8 T-cell': '0.9', 'Terminal effector memory CD8 T-cell': '0.9', 'Switched memory B-cell': '1.2', 'Plasmablast': '3.7', 'Non-switched memory B-cell': '2.6', 'Exhausted memory B-cell': '1.2', 'Progenitor cell': '8.0', 'Naive CD4 T-cell activated': '6.3', 'Naive CD8 T-cell activated': '6.3', 'Memory T-reg': '2.0', 'Naive T-reg': '3.8'}
null
{'Adipose Tissue': 5.820454318936878, 'Adrenal Gland': 9.379449612403102, 'Bladder': 8.06147619047619, 'Blood': 2.6586032077502693, 'Blood Vessel': 5.1121400749063675, 'Brain': 13.532603974261924, 'Breast': 6.341019607843137, 'Cervix Uteri': 13.574789473684213, 'Colon': 4.590135815147625, 'Esophagus': 4.815878546712803, 'Fallopian Tube': 11.151444444444444, 'Heart': 2.301748083623693, 'Kidney': 3.390912359550562, 'Liver': 3.571616371681416, 'Lung': 6.256196885813148, 'Muscle': 4.24469900373599, 'Nerve': 8.807029079159935, 'Ovary': 18.096344444444444, 'Pancreas': 2.2393905487804875, 'Pituitary': 8.06179151943463, 'Prostate': 7.2874, 'Salivary Gland': 5.6310617283950615, 'Skin': 10.102887783305691, 'Small Intestine': 4.153508021390374, 'Spleen': 9.021477178423236, 'Stomach': 4.785947910863509, 'Testis': 11.498180055401662, 'Thyroid': 7.111357886676876, 'Uterus': 12.457528169014084, 'Vagina': 7.359750000000001}
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null
Component of an E-cadherin/ catenin adhesion complex composed of at least E-cadherin/CDH1, beta-catenin/CTNNB1 or gamma-catenin/JUP, and potentially alpha-catenin/CTNNA1. Forms a ternary complex composed of ADAM10, CADH1 and EPHA4,
null
null
KLRG1, SPEF1, DLGAP5, AJAP1, RAPGEF2, RAB8B, PIP5K1C, PKP2, TRPV4, CTNNB1, CAV1, DDR1, TBC1D2, CTNNA1, JUP, CTNND1, PSEN1, LIMA1, CDH1, JUP, ADAM10, CADH1 , EPHA4,
null
null
null
null
Homodimer
null
79.91949
0.474025
87.155921
0.351447
1,061
P12830
Q8IWQ3-5
null
degron_data
CDH1
MGPWSRSLSALLLLLQVSSWLCQEPEPCHPGFDAESYTFTVPRRHLERGRVLGRVNFEDCTGRQRTAYFSLDTRFKVGTDGVITVKRPLRFHNPQIHFLVYAWDSTYRKFSTKVTLNTVGHHHRPPPHQASVSGIQAELLTFPNSSPGLRRQKRDWVIPPISCPENEKGPFPKNLVQIKSNKDKEGKVFYSITGQGADTPPVGVFIIERETGWLKVTEPLDRERIATYTLFSHAVSSNGNAVEDPMEILITVTDQNDNKPEFTQEVFKGSVMEGALPGTSVMEVTATDADDDVNTYNAAIAYTILSQDPELPDKNMFTINRNTGVISVVTTGLDRESFPTYTLVVQAADLQGEGLSTTATAVITVTDTNDNPPIFNPTTYKGQVPENEANVVITTLKVTDADAPNTPAWEAVYTILNDDGGQFVVTTNPVNNDGILKTAKGLDFEAKQQYILHVAVTNVVPFEVSLTTSTATVTVDVLDVNEAPIFVPPEKRVEVSEDFGVGQEITSYTAQEPDTFMEQKITYRIWRDTANWLEINPDTGAISTRAELDREDFEHVKNSTYTALIIATDNGSPVATGTGTLLLILSDVNDNAPIPEPRTIFFCERNPKPQVINIIDADLPPNTSPFTAELTHGASANWTIQYNDPTQESIILKPKMALEVGDYKINLKLMDNQNKDQVTTLEVSVCDCEGAAGVCRKAQPVEAGLQIPAILGILGGILALLILILLLLLFLRRRAVVKEPLLPPEDDTRDNVYYYDEEGGGEEDQDFDLSQLHRGLDARPEVTRNDVAPTLMSVPRYLPRPANPDEIGNFIDENLKAADTDPTAPPYDSLLVFDYEGSGSEAASLSSLNSSESDKDQDYDYLNEWGNRFKKLADMYGGGEDD
Homo sapiens
Cell junction, adherens junction, Cell membrane, Endosome, Golgi apparatus, trans-Golgi network, Cytoplasm, Cell junction, desmosome
Tissue enhanced (parathyroid)
{'Ciliated cells': '119.1', 'Basal respiratory cells': '71.1', 'Club cells': '97.3', 'Ionocytes': '81.0', 'Mucus glandular cells': '155.0', 'Serous glandular cells': '67.8', 'Gastric mucus-secreting cells': '133.2', 'Proximal enterocytes': '140.9', 'Paneth cells': '125.1', 'Distal enterocytes': '307.5', 'Intestinal goblet cells': '173.5', 'Exocrine glandular cells': '-0.605', 'Basal prostatic cells': '68.3', 'Prostatic glandular cells': '186.7', 'Breast glandular cells': '0.773', 'Breast myoepithelial cells': '0.700', 'Glandular and luminal cells': '313.0', 'Secretory cells': '82.3', 'Basal keratinocytes': '102.5', 'Suprabasal keratinocytes': '162.6', 'Basal squamous epithelial cells': '51.0', 'Squamous epithelial cells': '106.9', 'Alveolar cells type 1': '0.437', 'Alveolar cells type 2': '0.706', 'Salivary duct cells': '95.9', 'Ductal cells': '0.541', 'Hepatocytes': '0.600', 'Cholangiocytes': '129.7', 'Proximal tubular cells': '0.042', 'Distal tubular cells': '0.0', 'Collecting duct cells': '143.9', 'Mesothelial cells': '0.799', 'Sertoli cells': '0.252', 'Granulosa cells': '12.9', 'Enteroendocrine cells': '92.4', 'Pancreatic endocrine cells': '78.1', 'Leydig cells': '0.264', 'Excitatory neurons': '0.7', 'Inhibitory neurons': '1.3', 'Cone photoreceptor cells': '0.0', 'Rod photoreceptor cells': '0.0', 'Bipolar cells': '0.2', 'Horizontal cells': '0.6', 'Astrocytes': '0.6', 'Oligodendrocyte precursor cells': '0.5', 'Oligodendrocytes': '29.9', 'Microglial cells': '0.9', 'Muller glia cells': '0.1', 'Schwann cells': '0.131', 'Spermatogonia': '0.392', 'Spermatocytes': '0.193', 'Early spermatids': '-0.217', 'Late spermatids': '-0.290', 'Oocytes': '16.9', 'Cytotrophoblasts': '119.2', 'Syncytiotrophoblasts': '45.0', 'Extravillous trophoblasts': '24.9', 'Endothelial cells': '6.1', 'Lymphatic endothelial cells': '0.4', 'Cardiomyocytes': '0.135', 'Skeletal myocytes': '0.107', 'Smooth muscle cells': '5.8', 'Adipocytes': '2.1', 'Melanocytes': '0.335', 'Fibroblasts': '6.5', 'Peritubular cells': '0.210', 'Endometrial stromal cells': '27.7', 'Ovarian stromal cells': '0.7', 'Undifferentiated cells': '101.6', 'T-cells': '2.9', 'B-cells': '4.4', 'Plasma cells': '6.1', 'Nk-cells': '0.0', 'Granulocytes': '8.4', 'Monocytes': '0.0', 'Macrophages': '6.0', 'Hofbauer cells': '4.3', 'Kupffer cells': '1.0', 'Dendritic cells': '5.9', 'Langerhans cells': '0.304', 'Erythroid cells': '0.036', 'Adipocytes (Subcutaneous)': '-0.081', 'Adipocytes (Visceral)': '-0.209', 'Breast glandular cells (progenitors)': '0.538', 'Adipocytes (Breast)': '-0.689', 'Colon enterocytes': '0.790', 'Colon enteroendocrine cells': '0.112', 'Enteric glia cells': '-0.048', 'Mitotic cells (Colon)': '0.299', 'Mitotic cells (Heart)': '0.120', 'Podocytes': '-0.118', 'Ascending Loop of Henle cells': '0.475', 'Intercalated cells': '0.212', 'Cholangiocyte': '0.090', 'NK-cells (Liver)': '-0.005', 'Respiratory ciliated cells': '-0.012', 'Mitotic cells (Lung)': '0.071', 'NK-cells (Lung)': '-0.266', 'B-cells (Lung)': '-0.296', 'Alpha cells': '0.270', 'Beta cells': '0.152', 'Prostate glandular cells': '0.764', 'Prostate basal glandular cells': '0.540', 'Urothelial cells': '0.205', 'Keratinocyte (other)': '0.510', 'Keratinocyte (granular)': '0.055', 'Hair cortex cells': '0.080', 'Inner root sheath cells': '0.131', 'Outer root sheath cells': '0.175', 'Sebaceous gland cells': '0.156', 'Eccrine sweat gland cells': '-0.207', 'Adipocytes (Skin)': '-0.244', 'Mitotic cells (Skin)': '0.442', 'Parietal cells': '0.654', 'Chief cells': '0.649', 'Gastric mucous cells': '0.781', 'Gastric enteroendocrine cells': '0.590', 'Mitotic cells (Stomach)': '0.445', 'Parafollicular cells': '0.173', 'Thyroid glandular cells': '0.865', 'Mitotic cells (Thyroid)': '-0.081', 'Adrenal cortex cells': '0.051', 'Adrenal medulla cells': '0.087', 'Mitotic cells (Adrenal gland)': '0.072', 'Minor salivary glandular cells': '0.371', 'Minor salivary gland ductal cells': '-0.142', 'Minor salivary gland basal cells': '0.582', 'Mitotic cells (Minor salivary gland)': '0.567', 'Adipocytes (Minor salivary gland)': '0.050', 'Somatotropes': '0.121', 'Lactotropes': '0.322', 'Gonadotropes': '0.330', 'Corticotropes': '0.180', 'Thyrotropes': '0.496', 'Undifferentiated cells (Pituitary gland)': '-0.108', 'Mitotic cells (Spleen)': '-0.228', 'Platelets': '-0.050', 'Erythrocytes': '-0.158', 'Hematopoietic stem cells': '-0.211', 'B-cells (Spleen)': '0.266', 'NK-cells (Spleen)': '0.309', 'Amygdala excitatory': '1.0', 'Cerebellar inhibitory': '0.9', 'Cge interneuron': '0.7', 'Deep-layer corticothalamic and 6b': '1.5', 'Deep-layer intratelencephalic': '0.7', 'Deep-layer near-projecting': '0.7', 'Eccentric medium spiny neuron': '0.6', 'Hippocampal ca1-3': '1.9', 'Hippocampal ca4': '1.2', 'Hippocampal dentate gyrus': '1.1', 'Lamp5-lhx6 and chandelier': '0.5', 'Lower rhombic lip': '0.8', 'Mammillary body': '0.6', 'Medium spiny neuron': '0.7', 'Mge interneuron': '1.7', 'Midbrain-derived inhibitory': '0.7', 'Miscellaneous': '0.9', 'Splatter': '3.8', 'Thalamic excitatory': '0.5', 'Upper rhombic lip': '0.8', 'Upper-layer intratelencephalic': '0.6', 'Astrocyte': '4.4', 'Bergmann glia': '0.2', 'Central nervous system macrophage': '0.6', 'Choroid plexus epithelial cell': '52.1', 'Committed oligodendrocyte precursor': '41.5', 'Ependymal cell': '4.8', 'Oligodendrocyte': '53.1', 'Oligodendrocyte precursor cell': '2.4', 'Endothelial cell': '0.7', 'Pericyte': '0.3', 'Vascular associated smooth muscle cell': '0.0', 'Fibroblast': '17.4', 'Leukocyte': '1.1', 'Basophil': '0.0', 'Eosinophil': '0.0', 'Neutrophil': '0.0', 'Classical monocyte': '0.0', 'Non-classical monocyte': '0.0', 'Intermediate monocyte': '0.0', 'T-reg': '2.3', 'GdT-cell': '0.0', 'MAIT T-cell': '0.0', 'Memory CD4 T-cell': '0.0', 'Naive CD4 T-cell': '0.1', 'Memory CD8 T-cell': '0.2', 'Naive CD8 T-cell': '0.3', 'Memory B-cell': '0.0', 'Naive B-cell': '0.1', 'Plasmacytoid DC': '46.6', 'Myeloid DC': '8.5', 'NK-cell': '0.1', 'Total PBMC': '0.7', 'Vd2 gdTCR': '0.0', 'Memory CD4 T-cell Th1\\/Th17': '0.1', 'Memory CD4 T-cell Th17': '0.2', 'Memory CD4 T-cell Th2': '2.9', 'Non-Vd2 gdTCR': '0.1', 'Memory CD4 T-cell Th1': '0.3', 'Memory CD4 T-cell TFH': '0.5', 'Terminal effector memory CD4 T-cell': '0.0', 'Central memory CD8 T-cell': '4.8', 'Effector memory CD8 T-cell': '0.0', 'Terminal effector memory CD8 T-cell': '0.6', 'Non-switched memory B-cell': '0.0', 'Plasmablast': '3.3', 'Switched memory B-cell': '0.0', 'Exhausted memory B-cell': '0.7', 'Progenitor cell': '2.3', 'Memory T-reg': '1.3', 'Naive CD4 T-cell activated': '0.3', 'Naive CD8 T-cell activated': '0.6', 'Naive T-reg': '0.1'}
1O6S, 2O72, 2OMT, 2OMU, 2OMV, 2OMX, 2OMY, 2OMZ, 3FF7, 3FF8, 3L6X, 3L6Y, 4ZT1, 4ZTE, 6CXY, 6OLE, 6OLF, 6OLG, 6VEL, 7STZ, 8H62
{'Adipose Tissue': 1.2125261088039867, 'Adrenal Gland': 0.1914223992248062, 'Bladder': 39.2033519047619, 'Blood': 1.340954264800861, 'Blood Vessel': 0.3121561692883895, 'Brain': 0.8550442199091597, 'Breast': 38.54918344226579, 'Cervix Uteri': 23.539115789473684, 'Colon': 43.41292142490372, 'Esophagus': 53.97513367404844, 'Fallopian Tube': 14.900277777777776, 'Heart': 0.119140469221835, 'Kidney': 25.040449438202245, 'Liver': 26.60802654867257, 'Lung': 35.447986366782004, 'Muscle': 0.1378936151930261, 'Nerve': 17.518468982229404, 'Ovary': 3.6515122222222223, 'Pancreas': 56.89676829268293, 'Pituitary': 24.68741660777385, 'Prostate': 61.279967346938776, 'Salivary Gland': 92.01685185185184, 'Skin': 79.77571720232172, 'Small Intestine': 71.7519320855615, 'Spleen': 10.061029045643156, 'Stomach': 58.07813805013927, 'Testis': 0.8144204986149585, 'Thyroid': 135.176797856049, 'Uterus': 1.442593943661972, 'Vagina': 86.52345512820513}
BRSK2
MSPEGHPSRWARPRRPCICPSSLCSPREPRSGPAVGRGGAAHHRVPAGHTPGPQLLQPHLHLPQGQTWLCLQPSPAGLVKLGVHCVTCQKVAIKIVNREKLSESVLMKVEREIAILKLIEHPHVLKLHDVYENKKYLYLVLEHVSGGELFDYLVKKGRLTPKEARKFFRQIISALDFCHSHSICHRDLKPENLLLDEKNNIRIADFGMASLQVGDSLLETSCGSPHYACPEVIRGEKYDGRKADVWSCGVILFALLVGALPFDDDNLRQLLEKVKRGVFHMPHFIPPDCQSLLRGMIEVDAARRLTLEHIQKHIWYIGGKNEPEPEQPIPRKVQIRSLPSLEDIDPDVLDSMHSLGCFRDRNKLLQDLLSEEENQEKMIYFLLLDRKERYPSQEDEDLPPRNEIDPPRKRVDSPMLNRHGKRRPERKSMEVLSVTDGGSPVPARRAIEMAQHGQRSRSISGASSGLSTSPLSSPRVTPHPSPRGSPLPTPKGTPVHTPKESPAGTPNPTPPSSPSVGGVPWRARLNSIKNSFLGSPRFHRRKLQVPTPEEMSNLTPESSPELAKKSWFGNFISLEKEEQIFVVIKDKPLSSIKADIVHAFLSIPSLSHSVISQTSFRAEYKATGGPAVFQKPVKFQVDITYTEGGEAQKENGIYSVTFTLLSGPSRRFKRVVETIQAQLLSTHDPPAAQHLSDTTNCMEMMTGRLSKCDEKNGQAAQAPSTPAKRSAHGPLGDSAAAGPGPGGDAEYPTGKDTAKMGPPTARREQP
Homo sapiens
null
Not found
{}
null
{'Adipose Tissue': 1.1078286794019934, 'Adrenal Gland': 1.590517054263566, 'Bladder': 1.5991380952380951, 'Blood': 0.0983902142088267, 'Blood Vessel': 5.812490861423221, 'Brain': 46.96560900832702, 'Breast': 0.9734030501089324, 'Cervix Uteri': 3.4886631578947367, 'Colon': 3.494755327342747, 'Esophagus': 2.367677446366782, 'Fallopian Tube': 4.2613666666666665, 'Heart': 0.5245389430894309, 'Kidney': 0.4644759550561798, 'Liver': 0.1069390265486725, 'Lung': 0.70915553633218, 'Muscle': 0.2100322166874221, 'Nerve': 10.807190630048463, 'Ovary': 1.8053116666666664, 'Pancreas': 31.466067073170738, 'Pituitary': 21.962957597173144, 'Prostate': 2.429728979591837, 'Salivary Gland': 0.4094632716049383, 'Skin': 0.3155113272526257, 'Small Intestine': 2.2693465240641713, 'Spleen': 0.7963746887966805, 'Stomach': 2.0036961002785514, 'Testis': 16.159296398891968, 'Thyroid': 2.084484839203675, 'Uterus': 2.7068943661971834, 'Vagina': 2.075147435897436}
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73.27, 70.36, 72.63, 72.69, 68.11, 66.06, 60.67, 52.64, 44.07, 48.46, 43.79, 36.31]
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0.54, 0.27, 0.29, 0.51, 0.08, 0.77, 0.06, 0.62, 0.39, 0.34, 0.94, 0.83, 0.46, 0.51, 0.07, 0.17, 0.07, 0.41, 0.14, 0.31, 0.2, 0.36, 0.0, 0.13, 0.59, 0.53, 0.77, 0.2, 0.64, 0.35, 0.0, 0.02, 0.39, 0.18, 0.39, 0.57, 0.63, 0.39, 0.0, 0.32, 0.0, 0.18, 0.03, 0.29, 0.47, 0.55, 0.03, 0.34, 0.2, 0.45, 0.56, 0.17, 0.37, 0.59, 0.01, 0.39, 0.0, 0.39, 0.05, 0.28, 0.07, 0.29, 0.26, 0.64, 0.82, 0.64, 0.63, 0.76, 0.15, 0.39, 0.95, 0.57, 0.28, 0.58, 0.02, 0.43, 0.0, 0.29, 0.09, 0.4, 0.13, 0.49, 0.31, 0.53, 0.32, 0.66, 0.01, 0.71, 0.13, 0.56, 0.54, 0.84, 0.51, 0.06, 0.82, 0.14, 0.54, 0.07, 0.63, 0.05, 0.7, 0.17, 0.75, 0.51, 0.64, 0.36, 0.67, 0.15, 0.12, 0.61, 0.0, 0.33, 0.14, 0.62, 0.2, 0.52, 0.05, 0.14, 0.63, 0.95, 0.85, 0.32, 0.6, 0.1, 0.12, 0.17, 0.17, 0.06, 0.08, 0.41, 0.28, 0.55, 0.49, 0.09, 0.68, 0.23, 0.53, 0.64, 0.52, 0.42, 0.64, 0.64, 0.0, 0.08, 0.44, 0.13, 0.48, 0.52, 0.81, 0.44, 0.0, 0.26, 0.0, 0.21, 0.03, 0.46, 0.27, 0.71, 0.45, 0.06, 0.28, 0.28, 0.4, 0.65, 0.28, 0.46, 0.61, 0.0, 0.36, 0.0, 0.32, 0.01, 0.22, 0.0, 0.05, 0.0, 0.41, 0.46, 0.42, 0.82, 0.48, 0.4, 0.5, 0.17, 0.62, 0.06, 0.32, 0.0, 0.25, 0.0, 0.42, 0.08, 0.41, 0.27, 0.16, 0.04, 0.36, 0.32, 0.2, 0.0, 0.52, 0.04, 0.66, 0.47, 0.52, 0.78, 0.09, 0.77, 0.08, 0.6, 0.0, 0.31, 0.03, 0.58, 0.47, 0.59, 0.44, 0.23, 0.54, 0.1, 0.18, 0.45, 0.0, 0.53, 0.11, 0.59, 0.17, 0.51, 0.01, 0.19, 0.71, 0.77, 0.3, 0.44, 0.08, 0.14, 0.52, 0.05, 0.37, 0.1, 0.42, 0.23, 0.61, 0.43, 0.22, 0.96, 0.54, 0.4, 0.3, 0.07, 0.39, 0.17, 0.43, 0.38, 0.3, 0.8, 0.83, 0.44, 0.03, 0.11, 0.0, 0.23, 0.0, 0.31, 0.0, 0.38, 0.58, 0.51, 0.01, 0.49, 0.13, 0.26, 0.69, 0.46, 0.41, 0.51, 0.06, 0.51, 0.03, 0.38, 0.0, 0.06, 0.0, 0.34, 0.08, 0.53, 0.42, 0.88, 0.25, 0.75, 0.49, 1.0, 0.34, 0.86, 0.48, 0.18, 0.52, 0.01, 0.32, 0.0, 0.19, 0.0, 0.3, 0.05, 0.44, 0.27, 0.43, 0.11, 0.31, 0.39, 0.03, 0.55, 0.04, 0.52, 0.51, 0.64, 0.57, 0.19, 0.68, 0.13, 0.84, 0.06, 0.31, 0.07, 0.69, 0.26, 0.37, 0.53, 0.67, 0.5, 0.56, 0.14, 0.18, 0.47, 0.01, 0.47, 0.15, 0.61, 0.28, 0.2, 0.02, 0.76, 0.55, 0.31, 0.94, 0.22, 0.57, 0.17, 0.4, 0.07, 0.5, 0.31, 0.7, 0.2, 0.14, 0.3, 0.23, 0.58, 0.07, 0.06, 0.55, 0.15, 0.46, 0.43, 0.64, 0.53, 0.0, 0.18, 0.01, 0.23, 0.02, 0.63, 0.33, 0.79, 0.06, 0.38, 0.07, 0.14, 0.23, 0.68, 0.89, 0.29, 0.06, 0.72, 0.92, 0.24, 0.25, 0.0, 0.46, 0.02, 0.21, 0.01, 0.06, 0.0, 0.05, 0.07, 0.61, 0.17, 0.89, 0.72, 0.66, 0.14, 0.52, 0.07, 0.58, 0.01, 0.26, 0.0, 0.13, 0.0, 0.29, 0.04, 0.46, 0.27, 0.28, 0.23, 0.56, 0.32, 0.25, 0.0, 0.33, 0.05, 0.55, 0.5, 0.58, 0.53, 0.04, 0.27, 0.02, 0.04, 0.37, 0.67, 0.74, 0.35, 0.62, 0.54, 0.26, 0.46, 0.0, 0.47, 0.09, 0.45, 0.15, 0.39, 0.05, 0.44, 0.85, 0.56, 0.11, 0.11, 0.35, 0.42, 0.03, 0.32, 0.12, 0.49, 0.19, 0.25, 0.8, 0.6, 0.09, 0.49, 0.57, 0.36, 0.04, 0.35, 0.28, 0.52, 0.39, 0.5, 0.28, 0.93, 0.47, 0.3, 0.47, 0.08, 0.02, 0.18, 0.01, 0.34, 0.23, 0.55, 0.57, 0.91, 0.1, 0.78, 0.52, 0.34, 0.61, 0.24, 0.75, 0.0, 0.2, 0.02, 0.24, 0.0, 0.18, 0.04, 0.44, 0.59, 0.71, 0.29, 0.52, 0.37, 0.5, 0.11, 0.6, 0.02, 0.48, 0.01, 0.16, 0.04, 0.35, 0.66, 0.47, 0.74, 0.14, 0.62, 0.16, 0.77, 0.79, 0.27, 0.93, 0.69, 0.88, 0.88, 0.85, 0.87, 0.91, 0.92, 0.82, 0.63, 0.75, 0.7, 0.7, 0.38, 0.43, 0.64, 0.55, 0.54, 0.59, 0.45, 0.47, 0.5, 0.58, 0.52, 0.61, 0.57, 0.52, 0.68, 0.44, 0.6, 0.61, 0.58, 0.55, 0.5, 0.61, 0.61, 0.86, 0.86, 0.75, 0.91, 0.96, 0.93, 1.0, 0.87, 0.97, 0.91, 0.95, 0.86, 0.98, 0.93, 0.88, 0.59, 0.87, 0.7, 0.67, 0.85, 0.89, 0.88, 0.91, 0.93, 0.88, 0.99, 0.92, 1.0, 0.79, 0.9, 1.0, 0.94, 1.0, 0.97, 0.96, 0.9, 0.63, 0.68, 0.48, 0.54, 0.8, 0.7, 0.7, 0.95, 0.87, 0.77, 0.84, 0.79, 0.89, 0.95, 0.8, 0.77, 0.51, 0.87, 0.7, 0.52, 0.84, 0.91, 0.51, 0.96, 0.79, 0.92, 0.84, 0.21, 0.89, 0.53, 0.52, 0.89, 0.86, 0.26, 0.91, 0.45, 0.68, 0.84, 0.48, 0.44, 0.51, 0.62, 0.28, 0.59, 0.63, 0.57, 0.15, 0.55, 0.66, 0.1, 0.38, 0.74, 0.65, 0.17, 0.43, 0.66, 0.41, 0.8, 0.75, 0.9, 0.93, 0.52, 0.76, 0.89, 0.87, 0.76, 0.92, 0.91, 0.75, 0.61, 0.96, 0.89, 0.73, 0.97, 0.68, 0.87, 0.55, 0.85, 0.77, 0.69, 0.76, 0.98, 0.83, 0.68, 0.82, 0.74, 0.65, 0.96, 0.93, 0.54, 0.64, 0.28, 0.54, 0.52, 0.16, 0.51, 0.88, 0.6, 0.4, 0.88, 0.95, 0.33, 0.56, 0.73, 0.39, 0.06, 0.61, 0.75, 0.47, 0.19, 0.87, 0.7, 0.97, 0.94, 0.97]
null
null
null
Component of an E-cadherin/ catenin adhesion complex composed of at least E-cadherin/CDH1, beta-catenin/CTNNB1 or gamma-catenin/JUP, and potentially alpha-catenin/CTNNA1. Forms a ternary complex composed of ADAM10, CADH1 and EPHA4,
null
null
KLRG1, SPEF1, DLGAP5, AJAP1, RAPGEF2, RAB8B, PIP5K1C, PKP2, TRPV4, CTNNB1, CAV1, DDR1, TBC1D2, CTNNA1, JUP, CTNND1, PSEN1, LIMA1, CDH1, JUP, ADAM10, CADH1 , EPHA4,
null
null
null
null
Homodimer
null
79.91949
0.474025
null
null
866
P12830
Q8NI77
null
degron_data
CDH1
MGPWSRSLSALLLLLQVSSWLCQEPEPCHPGFDAESYTFTVPRRHLERGRVLGRVNFEDCTGRQRTAYFSLDTRFKVGTDGVITVKRPLRFHNPQIHFLVYAWDSTYRKFSTKVTLNTVGHHHRPPPHQASVSGIQAELLTFPNSSPGLRRQKRDWVIPPISCPENEKGPFPKNLVQIKSNKDKEGKVFYSITGQGADTPPVGVFIIERETGWLKVTEPLDRERIATYTLFSHAVSSNGNAVEDPMEILITVTDQNDNKPEFTQEVFKGSVMEGALPGTSVMEVTATDADDDVNTYNAAIAYTILSQDPELPDKNMFTINRNTGVISVVTTGLDRESFPTYTLVVQAADLQGEGLSTTATAVITVTDTNDNPPIFNPTTYKGQVPENEANVVITTLKVTDADAPNTPAWEAVYTILNDDGGQFVVTTNPVNNDGILKTAKGLDFEAKQQYILHVAVTNVVPFEVSLTTSTATVTVDVLDVNEAPIFVPPEKRVEVSEDFGVGQEITSYTAQEPDTFMEQKITYRIWRDTANWLEINPDTGAISTRAELDREDFEHVKNSTYTALIIATDNGSPVATGTGTLLLILSDVNDNAPIPEPRTIFFCERNPKPQVINIIDADLPPNTSPFTAELTHGASANWTIQYNDPTQESIILKPKMALEVGDYKINLKLMDNQNKDQVTTLEVSVCDCEGAAGVCRKAQPVEAGLQIPAILGILGGILALLILILLLLLFLRRRAVVKEPLLPPEDDTRDNVYYYDEEGGGEEDQDFDLSQLHRGLDARPEVTRNDVAPTLMSVPRYLPRPANPDEIGNFIDENLKAADTDPTAPPYDSLLVFDYEGSGSEAASLSSLNSSESDKDQDYDYLNEWGNRFKKLADMYGGGEDD
Homo sapiens
Cell junction, adherens junction, Cell membrane, Endosome, Golgi apparatus, trans-Golgi network, Cytoplasm, Cell junction, desmosome
Tissue enhanced (parathyroid)
{'Ciliated cells': '119.1', 'Basal respiratory cells': '71.1', 'Club cells': '97.3', 'Ionocytes': '81.0', 'Mucus glandular cells': '155.0', 'Serous glandular cells': '67.8', 'Gastric mucus-secreting cells': '133.2', 'Proximal enterocytes': '140.9', 'Paneth cells': '125.1', 'Distal enterocytes': '307.5', 'Intestinal goblet cells': '173.5', 'Exocrine glandular cells': '-0.605', 'Basal prostatic cells': '68.3', 'Prostatic glandular cells': '186.7', 'Breast glandular cells': '0.773', 'Breast myoepithelial cells': '0.700', 'Glandular and luminal cells': '313.0', 'Secretory cells': '82.3', 'Basal keratinocytes': '102.5', 'Suprabasal keratinocytes': '162.6', 'Basal squamous epithelial cells': '51.0', 'Squamous epithelial cells': '106.9', 'Alveolar cells type 1': '0.437', 'Alveolar cells type 2': '0.706', 'Salivary duct cells': '95.9', 'Ductal cells': '0.541', 'Hepatocytes': '0.600', 'Cholangiocytes': '129.7', 'Proximal tubular cells': '0.042', 'Distal tubular cells': '0.0', 'Collecting duct cells': '143.9', 'Mesothelial cells': '0.799', 'Sertoli cells': '0.252', 'Granulosa cells': '12.9', 'Enteroendocrine cells': '92.4', 'Pancreatic endocrine cells': '78.1', 'Leydig cells': '0.264', 'Excitatory neurons': '0.7', 'Inhibitory neurons': '1.3', 'Cone photoreceptor cells': '0.0', 'Rod photoreceptor cells': '0.0', 'Bipolar cells': '0.2', 'Horizontal cells': '0.6', 'Astrocytes': '0.6', 'Oligodendrocyte precursor cells': '0.5', 'Oligodendrocytes': '29.9', 'Microglial cells': '0.9', 'Muller glia cells': '0.1', 'Schwann cells': '0.131', 'Spermatogonia': '0.392', 'Spermatocytes': '0.193', 'Early spermatids': '-0.217', 'Late spermatids': '-0.290', 'Oocytes': '16.9', 'Cytotrophoblasts': '119.2', 'Syncytiotrophoblasts': '45.0', 'Extravillous trophoblasts': '24.9', 'Endothelial cells': '6.1', 'Lymphatic endothelial cells': '0.4', 'Cardiomyocytes': '0.135', 'Skeletal myocytes': '0.107', 'Smooth muscle cells': '5.8', 'Adipocytes': '2.1', 'Melanocytes': '0.335', 'Fibroblasts': '6.5', 'Peritubular cells': '0.210', 'Endometrial stromal cells': '27.7', 'Ovarian stromal cells': '0.7', 'Undifferentiated cells': '101.6', 'T-cells': '2.9', 'B-cells': '4.4', 'Plasma cells': '6.1', 'Nk-cells': '0.0', 'Granulocytes': '8.4', 'Monocytes': '0.0', 'Macrophages': '6.0', 'Hofbauer cells': '4.3', 'Kupffer cells': '1.0', 'Dendritic cells': '5.9', 'Langerhans cells': '0.304', 'Erythroid cells': '0.036', 'Adipocytes (Subcutaneous)': '-0.081', 'Adipocytes (Visceral)': '-0.209', 'Breast glandular cells (progenitors)': '0.538', 'Adipocytes (Breast)': '-0.689', 'Colon enterocytes': '0.790', 'Colon enteroendocrine cells': '0.112', 'Enteric glia cells': '-0.048', 'Mitotic cells (Colon)': '0.299', 'Mitotic cells (Heart)': '0.120', 'Podocytes': '-0.118', 'Ascending Loop of Henle cells': '0.475', 'Intercalated cells': '0.212', 'Cholangiocyte': '0.090', 'NK-cells (Liver)': '-0.005', 'Respiratory ciliated cells': '-0.012', 'Mitotic cells (Lung)': '0.071', 'NK-cells (Lung)': '-0.266', 'B-cells (Lung)': '-0.296', 'Alpha cells': '0.270', 'Beta cells': '0.152', 'Prostate glandular cells': '0.764', 'Prostate basal glandular cells': '0.540', 'Urothelial cells': '0.205', 'Keratinocyte (other)': '0.510', 'Keratinocyte (granular)': '0.055', 'Hair cortex cells': '0.080', 'Inner root sheath cells': '0.131', 'Outer root sheath cells': '0.175', 'Sebaceous gland cells': '0.156', 'Eccrine sweat gland cells': '-0.207', 'Adipocytes (Skin)': '-0.244', 'Mitotic cells (Skin)': '0.442', 'Parietal cells': '0.654', 'Chief cells': '0.649', 'Gastric mucous cells': '0.781', 'Gastric enteroendocrine cells': '0.590', 'Mitotic cells (Stomach)': '0.445', 'Parafollicular cells': '0.173', 'Thyroid glandular cells': '0.865', 'Mitotic cells (Thyroid)': '-0.081', 'Adrenal cortex cells': '0.051', 'Adrenal medulla cells': '0.087', 'Mitotic cells (Adrenal gland)': '0.072', 'Minor salivary glandular cells': '0.371', 'Minor salivary gland ductal cells': '-0.142', 'Minor salivary gland basal cells': '0.582', 'Mitotic cells (Minor salivary gland)': '0.567', 'Adipocytes (Minor salivary gland)': '0.050', 'Somatotropes': '0.121', 'Lactotropes': '0.322', 'Gonadotropes': '0.330', 'Corticotropes': '0.180', 'Thyrotropes': '0.496', 'Undifferentiated cells (Pituitary gland)': '-0.108', 'Mitotic cells (Spleen)': '-0.228', 'Platelets': '-0.050', 'Erythrocytes': '-0.158', 'Hematopoietic stem cells': '-0.211', 'B-cells (Spleen)': '0.266', 'NK-cells (Spleen)': '0.309', 'Amygdala excitatory': '1.0', 'Cerebellar inhibitory': '0.9', 'Cge interneuron': '0.7', 'Deep-layer corticothalamic and 6b': '1.5', 'Deep-layer intratelencephalic': '0.7', 'Deep-layer near-projecting': '0.7', 'Eccentric medium spiny neuron': '0.6', 'Hippocampal ca1-3': '1.9', 'Hippocampal ca4': '1.2', 'Hippocampal dentate gyrus': '1.1', 'Lamp5-lhx6 and chandelier': '0.5', 'Lower rhombic lip': '0.8', 'Mammillary body': '0.6', 'Medium spiny neuron': '0.7', 'Mge interneuron': '1.7', 'Midbrain-derived inhibitory': '0.7', 'Miscellaneous': '0.9', 'Splatter': '3.8', 'Thalamic excitatory': '0.5', 'Upper rhombic lip': '0.8', 'Upper-layer intratelencephalic': '0.6', 'Astrocyte': '4.4', 'Bergmann glia': '0.2', 'Central nervous system macrophage': '0.6', 'Choroid plexus epithelial cell': '52.1', 'Committed oligodendrocyte precursor': '41.5', 'Ependymal cell': '4.8', 'Oligodendrocyte': '53.1', 'Oligodendrocyte precursor cell': '2.4', 'Endothelial cell': '0.7', 'Pericyte': '0.3', 'Vascular associated smooth muscle cell': '0.0', 'Fibroblast': '17.4', 'Leukocyte': '1.1', 'Basophil': '0.0', 'Eosinophil': '0.0', 'Neutrophil': '0.0', 'Classical monocyte': '0.0', 'Non-classical monocyte': '0.0', 'Intermediate monocyte': '0.0', 'T-reg': '2.3', 'GdT-cell': '0.0', 'MAIT T-cell': '0.0', 'Memory CD4 T-cell': '0.0', 'Naive CD4 T-cell': '0.1', 'Memory CD8 T-cell': '0.2', 'Naive CD8 T-cell': '0.3', 'Memory B-cell': '0.0', 'Naive B-cell': '0.1', 'Plasmacytoid DC': '46.6', 'Myeloid DC': '8.5', 'NK-cell': '0.1', 'Total PBMC': '0.7', 'Vd2 gdTCR': '0.0', 'Memory CD4 T-cell Th1\\/Th17': '0.1', 'Memory CD4 T-cell Th17': '0.2', 'Memory CD4 T-cell Th2': '2.9', 'Non-Vd2 gdTCR': '0.1', 'Memory CD4 T-cell Th1': '0.3', 'Memory CD4 T-cell TFH': '0.5', 'Terminal effector memory CD4 T-cell': '0.0', 'Central memory CD8 T-cell': '4.8', 'Effector memory CD8 T-cell': '0.0', 'Terminal effector memory CD8 T-cell': '0.6', 'Non-switched memory B-cell': '0.0', 'Plasmablast': '3.3', 'Switched memory B-cell': '0.0', 'Exhausted memory B-cell': '0.7', 'Progenitor cell': '2.3', 'Memory T-reg': '1.3', 'Naive CD4 T-cell activated': '0.3', 'Naive CD8 T-cell activated': '0.6', 'Naive T-reg': '0.1'}
1O6S, 2O72, 2OMT, 2OMU, 2OMV, 2OMX, 2OMY, 2OMZ, 3FF7, 3FF8, 3L6X, 3L6Y, 4ZT1, 4ZTE, 6CXY, 6OLE, 6OLF, 6OLG, 6VEL, 7STZ, 8H62
{'Adipose Tissue': 1.2125261088039867, 'Adrenal Gland': 0.1914223992248062, 'Bladder': 39.2033519047619, 'Blood': 1.340954264800861, 'Blood Vessel': 0.3121561692883895, 'Brain': 0.8550442199091597, 'Breast': 38.54918344226579, 'Cervix Uteri': 23.539115789473684, 'Colon': 43.41292142490372, 'Esophagus': 53.97513367404844, 'Fallopian Tube': 14.900277777777776, 'Heart': 0.119140469221835, 'Kidney': 25.040449438202245, 'Liver': 26.60802654867257, 'Lung': 35.447986366782004, 'Muscle': 0.1378936151930261, 'Nerve': 17.518468982229404, 'Ovary': 3.6515122222222223, 'Pancreas': 56.89676829268293, 'Pituitary': 24.68741660777385, 'Prostate': 61.279967346938776, 'Salivary Gland': 92.01685185185184, 'Skin': 79.77571720232172, 'Small Intestine': 71.7519320855615, 'Spleen': 10.061029045643156, 'Stomach': 58.07813805013927, 'Testis': 0.8144204986149585, 'Thyroid': 135.176797856049, 'Uterus': 1.442593943661972, 'Vagina': 86.52345512820513}
KIF18A
MSVTEEDLCHHMKVVVRVRPENTKEKAAGFHKVVHVVDKHILVFDPKQEEVSFFHGKKTTNQNVIKKQNKDLKFVFDAVFDETSTQSEVFEHTTKPILRSFLNGYNCTVLAYGATGAGKTHTMLGSADEPGVMYLTMLHLYKCMDEIKEEKICSTAVSYLEVYNEQIRDLLVNSGPLAVREDTQKGVVVHGLTLHQPKSSEEILHLLDNGNKNRTQHPTDMNATSSRSHAVFQIYLRQQDKTASINQNVRIAKMSLIDLAGSERASTSGAKGTRFVEGTNINRSLLALGNVINALADSKRKNQHIPYRNSKLTRLLKDSLGGNCQTIMIAAVSPSSVFYDDTYNTLKYANRAKDIKSSLKSNVLNVNNHITQYVKICNEQKAEILLLKEKLKAYEEQKAFTNENDQAKLMISNPQEKEIERFQEILNCLFQNREEIRQEYLKLEMLLKENELKSFYQQQCHKQIEMMCSEDKVEKATGKRDHRLAMLKTRRSYLEKRREEELKQFDENTNWLHRVEKEMGLLSQNGHIPKELKKDLHCHHLHLQNKDLKAQIRHMMDLACLQEQQHRQTEAVLNALLPTLRKQYCTLKEAGLSNAAFESDFKEIEHLVERKKVVVWADQTAEQPKQNDLPGISVLMTFPQLGPVQPIPCCSSSGGTNLVKIPTEKRTRRKLMPSPLKGQHTLKSPPSQSVQLNDSLSKELQPIVYTPEDCRKAFQNPSTVTLMKPSSFTTSFQAISSNINSDNCLKMLCEVAIPHNRRKECGQEDLDSTFTICEDIKSSKCKLPEQESLPNDNKDILQRLDPSSFSTKHSMPVPSMVPSYMAMTTAAKRKRKLTSSTSNSSLTADVNSGFAKRVRQDNSSEKHLQENKPTMEHKRNICKINPSMVRKFGRNISKGNLR
Homo sapiens
Cell projection, ruffle, Cytoplasm, Nucleus, Cytoplasm, cytoskeleton, microtubule organizing center, centrosome
Group enriched (bone marrow, lymphoid tissue, testis)
{'Ciliated cells': '1.9', 'Basal respiratory cells': '1.5', 'Club cells': '0.7', 'Ionocytes': '1.1', 'Mucus glandular cells': '1.2', 'Serous glandular cells': '0.1', 'Gastric mucus-secreting cells': '1.2', 'Proximal enterocytes': '0.5', 'Paneth cells': '0.1', 'Distal enterocytes': '1.3', 'Intestinal goblet cells': '2.1', 'Exocrine glandular cells': '-0.401', 'Basal prostatic cells': '0.2', 'Prostatic glandular cells': '0.1', 'Breast glandular cells': '0.457', 'Breast myoepithelial cells': '0.532', 'Glandular and luminal cells': '3.1', 'Secretory cells': '1.7', 'Basal keratinocytes': '3.3', 'Suprabasal keratinocytes': '1.3', 'Basal squamous epithelial cells': '1.8', 'Squamous epithelial cells': '4.0', 'Alveolar cells type 1': '0.103', 'Alveolar cells type 2': '0.193', 'Salivary duct cells': '1.2', 'Ductal cells': '0.405', 'Hepatocytes': '0.238', 'Cholangiocytes': '0.0', 'Proximal tubular cells': '0.095', 'Distal tubular cells': '0.0', 'Collecting duct cells': '0.0', 'Mesothelial cells': '0.254', 'Sertoli cells': '-0.379', 'Granulosa cells': '4.0', 'Enteroendocrine cells': '1.9', 'Pancreatic endocrine cells': '0.0', 'Leydig cells': '-0.364', 'Excitatory neurons': '0.2', 'Inhibitory neurons': '0.1', 'Cone photoreceptor cells': '1.7', 'Rod photoreceptor cells': '1.2', 'Bipolar cells': '0.0', 'Horizontal cells': '0.0', 'Astrocytes': '0.0', 'Oligodendrocyte precursor cells': '0.5', 'Oligodendrocytes': '0.9', 'Microglial cells': '0.9', 'Muller glia cells': '0.4', 'Schwann cells': '0.020', 'Spermatogonia': '0.022', 'Spermatocytes': '0.558', 'Early spermatids': '0.792', 'Late spermatids': '0.413', 'Oocytes': '23.5', 'Cytotrophoblasts': '4.6', 'Syncytiotrophoblasts': '1.2', 'Extravillous trophoblasts': '6.6', 'Endothelial cells': '1.0', 'Lymphatic endothelial cells': '0.4', 'Cardiomyocytes': '0.295', 'Skeletal myocytes': '0.062', 'Smooth muscle cells': '1.0', 'Adipocytes': '1.1', 'Melanocytes': '0.430', 'Fibroblasts': '1.0', 'Peritubular cells': '-0.276', 'Endometrial stromal cells': '2.1', 'Ovarian stromal cells': '1.0', 'Undifferentiated cells': '6.7', 'T-cells': '3.1', 'B-cells': '2.8', 'Plasma cells': '5.6', 'Nk-cells': '3.0', 'Granulocytes': '1.7', 'Monocytes': '0.9', 'Macrophages': '1.8', 'Hofbauer cells': '1.4', 'Kupffer cells': '2.9', 'Dendritic cells': '1.2', 'Langerhans cells': '0.229', 'Erythroid cells': '0.138', 'Adipocytes (Subcutaneous)': '-0.347', 'Adipocytes (Visceral)': '-0.191', 'Breast glandular cells (progenitors)': '0.388', 'Adipocytes (Breast)': '-0.461', 'Colon enterocytes': '0.285', 'Colon enteroendocrine cells': '0.021', 'Enteric glia cells': '0.004', 'Mitotic cells (Colon)': '0.433', 'Mitotic cells (Heart)': '0.533', 'Podocytes': '-0.198', 'Ascending Loop of Henle cells': '0.370', 'Intercalated cells': '-0.198', 'Cholangiocyte': '0.289', 'NK-cells (Liver)': '-0.027', 'Respiratory ciliated cells': '0.065', 'Mitotic cells (Lung)': '0.451', 'NK-cells (Lung)': '0.085', 'B-cells (Lung)': '0.070', 'Alpha cells': '0.167', 'Beta cells': '0.084', 'Prostate glandular cells': '-0.200', 'Prostate basal glandular cells': '0.128', 'Urothelial cells': '0.174', 'Keratinocyte (other)': '0.279', 'Keratinocyte (granular)': '-0.111', 'Hair cortex cells': '-0.031', 'Inner root sheath cells': '0.109', 'Outer root sheath cells': '0.168', 'Sebaceous gland cells': '0.082', 'Eccrine sweat gland cells': '0.005', 'Adipocytes (Skin)': '-0.151', 'Mitotic cells (Skin)': '0.843', 'Parietal cells': '0.015', 'Chief cells': '0.006', 'Gastric mucous cells': '0.452', 'Gastric enteroendocrine cells': '0.112', 'Mitotic cells (Stomach)': '0.816', 'Parafollicular cells': '0.111', 'Thyroid glandular cells': '0.370', 'Mitotic cells (Thyroid)': '0.101', 'Adrenal cortex cells': '0.371', 'Adrenal medulla cells': '0.025', 'Mitotic cells (Adrenal gland)': '0.747', 'Minor salivary glandular cells': '0.163', 'Minor salivary gland ductal cells': '-0.264', 'Minor salivary gland basal cells': '0.689', 'Mitotic cells (Minor salivary gland)': '0.874', 'Adipocytes (Minor salivary gland)': '0.187', 'Somatotropes': '-0.276', 'Lactotropes': '-0.282', 'Gonadotropes': '-0.042', 'Corticotropes': '-0.260', 'Thyrotropes': '-0.131', 'Undifferentiated cells (Pituitary gland)': '0.551', 'Mitotic cells (Spleen)': '0.859', 'Platelets': '0.027', 'Erythrocytes': '0.286', 'Hematopoietic stem cells': '0.247', 'B-cells (Spleen)': '-0.037', 'NK-cells (Spleen)': '-0.056', 'Amygdala excitatory': '0.6', 'Cerebellar inhibitory': '0.1', 'Cge interneuron': '0.1', 'Deep-layer corticothalamic and 6b': '0.2', 'Deep-layer intratelencephalic': '0.6', 'Deep-layer near-projecting': '0.1', 'Eccentric medium spiny neuron': '0.3', 'Hippocampal ca1-3': '0.4', 'Hippocampal ca4': '0.7', 'Hippocampal dentate gyrus': '2.9', 'Lamp5-lhx6 and chandelier': '0.1', 'Lower rhombic lip': '0.9', 'Mammillary body': '4.0', 'Medium spiny neuron': '0.3', 'Mge interneuron': '0.1', 'Midbrain-derived inhibitory': '0.4', 'Miscellaneous': '0.3', 'Splatter': '0.4', 'Thalamic excitatory': '0.4', 'Upper rhombic lip': '0.3', 'Upper-layer intratelencephalic': '0.3', 'Astrocyte': '1.2', 'Bergmann glia': '1.8', 'Central nervous system macrophage': '2.5', 'Choroid plexus epithelial cell': '1.6', 'Committed oligodendrocyte precursor': '0.6', 'Ependymal cell': '4.7', 'Oligodendrocyte': '2.0', 'Oligodendrocyte precursor cell': '0.9', 'Endothelial cell': '0.5', 'Pericyte': '0.3', 'Vascular associated smooth muscle cell': '7.7', 'Fibroblast': '0.4', 'Leukocyte': '4.8', 'Basophil': '1.9', 'Eosinophil': '0.3', 'Neutrophil': '0.0', 'Classical monocyte': '1.1', 'Non-classical monocyte': '0.6', 'Intermediate monocyte': '0.0', 'T-reg': '1.4', 'GdT-cell': '0.1', 'MAIT T-cell': '1.3', 'Memory CD4 T-cell': '0.4', 'Naive CD4 T-cell': '0.9', 'Memory CD8 T-cell': '0.2', 'Naive CD8 T-cell': '0.6', 'Memory B-cell': '1.0', 'Naive B-cell': '2.5', 'Plasmacytoid DC': '0.5', 'Myeloid DC': '1.3', 'NK-cell': '1.8', 'Total PBMC': '0.5', 'Vd2 gdTCR': '0.8', 'Memory CD4 T-cell Th1\\/Th17': '1.1', 'Memory CD4 T-cell Th17': '1.4', 'Memory CD4 T-cell Th2': '1.5', 'Non-Vd2 gdTCR': '0.8', 'Memory CD4 T-cell Th1': '1.1', 'Memory CD4 T-cell TFH': '0.9', 'Terminal effector memory CD4 T-cell': '1.3', 'Central memory CD8 T-cell': '0.6', 'Effector memory CD8 T-cell': '3.0', 'Terminal effector memory CD8 T-cell': '1.2', 'Non-switched memory B-cell': '2.5', 'Plasmablast': '5.7', 'Switched memory B-cell': '2.4', 'Exhausted memory B-cell': '3.2', 'Progenitor cell': '1.7', 'Memory T-reg': '2.4', 'Naive CD4 T-cell activated': '1.0', 'Naive CD8 T-cell activated': '1.2', 'Naive T-reg': '1.2'}
3LRE, 5OAM, 5OCU, 5OGC, 7RSI
{'Adipose Tissue': 0.4104360049833886, 'Adrenal Gland': 0.2470265116279069, 'Bladder': 0.37954, 'Blood': 4.028946421959096, 'Blood Vessel': 0.5657229138576779, 'Brain': 0.1335050071915215, 'Breast': 0.4532280392156863, 'Cervix Uteri': 0.5301626315789474, 'Colon': 0.6927017098844673, 'Esophagus': 1.0244078117647055, 'Fallopian Tube': 0.4102777777777777, 'Heart': 0.0943501010452961, 'Kidney': 0.2888380898876404, 'Liver': 0.1270377389380531, 'Lung': 1.380150034602076, 'Muscle': 0.1946960896637609, 'Nerve': 0.3874349596122778, 'Ovary': 0.5054153888888888, 'Pancreas': 0.1211120579268292, 'Pituitary': 0.3888806360424028, 'Prostate': 0.4077087346938775, 'Salivary Gland': 0.5695219753086419, 'Skin': 4.582113001658374, 'Small Intestine': 1.2864200534759358, 'Spleen': 1.3268427385892116, 'Stomach': 0.5775858217270194, 'Testis': 19.19371191135734, 'Thyroid': 1.6251788667687597, 'Uterus': 0.4364119014084507, 'Vagina': 1.2061108974358974}
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0.31, 0.76, 0.7, 0.11, 0.48, 0.11, 0.6, 0.45, 0.44, 0.99, 0.96, 0.73, 0.26, 0.14, 0.35, 0.2, 0.6, 0.6, 0.17, 0.29, 0.61, 0.29, 0.45, 0.08, 0.79, 0.31, 0.15, 0.67, 0.43, 0.01, 0.34, 0.6, 0.17, 0.04, 0.53, 0.3, 0.0, 0.18, 0.56, 0.47, 0.04, 0.4, 0.79, 0.33, 0.94, 0.48, 0.58, 0.86, 0.55, 0.22, 0.06, 0.33, 0.23, 0.37, 0.0, 0.01, 0.03, 0.04, 0.0, 0.09, 0.0, 0.31, 0.01, 0.46, 0.04, 0.21, 0.43, 0.48, 0.71, 0.73, 0.47, 0.69, 0.52, 0.25, 0.36, 0.04, 0.31, 0.37, 0.04, 0.2, 0.0, 0.05, 0.0, 0.0, 0.05, 0.0, 0.0, 0.04, 0.19, 0.36, 0.66, 0.26, 0.8, 0.88, 0.52, 0.82, 0.32, 0.9, 0.6, 0.77, 0.61, 0.57, 0.55, 0.14, 0.16, 0.49, 0.25, 0.07, 0.26, 0.52, 0.03, 0.08, 0.61, 0.07, 0.03, 0.12, 0.41, 0.0, 0.02, 0.4, 0.13, 0.18, 0.19, 0.25, 0.56, 0.91, 0.59, 0.89, 0.98, 0.4, 0.86, 0.32, 0.16, 0.12, 0.78, 0.46, 0.02, 0.24, 0.0, 0.0, 0.22, 0.14, 0.05, 0.38, 0.26, 0.07, 0.0, 0.37, 0.27, 0.21, 0.03, 0.24, 0.03, 0.01, 0.0, 0.01, 0.01, 0.02, 0.02, 0.02, 0.0, 0.0, 0.2, 0.58, 0.26, 0.15, 0.62, 0.25, 0.03, 0.26, 0.37, 0.02, 0.0, 0.49, 0.05, 0.0, 0.39, 0.26, 0.0, 0.33, 0.48, 0.0, 0.48, 0.05, 0.49, 0.14, 0.71, 0.3, 0.26, 0.49, 0.55, 0.53, 0.38, 0.74, 0.14, 0.68, 0.73, 0.63, 0.49, 0.38, 0.56, 0.59, 0.33, 0.46, 0.54, 0.5, 0.4, 0.63, 0.5, 0.6, 0.52, 0.66, 0.5, 0.48, 0.64, 0.66, 0.59, 0.54, 0.56, 0.39, 0.63, 0.62, 0.41, 0.61, 0.58, 0.41, 0.61, 0.64, 0.44, 0.57, 0.87, 0.72, 0.51, 0.93, 0.91, 0.9, 0.93, 0.95, 0.55, 0.6, 0.7, 0.6, 0.51, 0.61, 0.47, 0.19, 0.62, 0.66, 0.07, 0.32, 0.73, 0.24, 0.0, 0.46, 0.55, 0.0, 0.05, 0.6, 0.38, 0.11, 0.19, 0.54, 0.05, 0.17, 0.52, 0.32, 0.19, 0.03, 0.39, 0.02, 0.23, 0.17, 0.29, 0.11, 0.24, 0.26, 0.08, 0.31, 0.0, 0.42, 0.24, 0.22, 0.13, 0.17, 0.29, 0.42, 0.42, 0.12, 0.44, 0.35, 0.27, 0.59, 0.78, 0.78, 0.43, 0.57, 0.83, 0.52, 0.59, 0.18, 0.7, 0.55, 0.14, 0.29, 0.53, 0.65, 0.22, 0.6, 0.66, 0.57, 0.18, 0.49, 0.62, 0.18, 0.76, 0.59, 0.48, 0.45, 0.57, 0.54, 0.02, 0.41, 0.63, 0.29, 0.32, 0.51, 0.43, 0.11, 0.47, 0.53, 0.45, 0.26, 0.53, 0.65, 0.03, 0.23, 0.52, 0.33, 0.05, 0.56, 0.65, 0.05, 0.26, 0.73, 0.51, 0.0, 0.07, 0.74, 0.25, 0.3, 0.99, 0.8, 0.6, 0.68, 0.29, 0.16, 0.78, 0.62, 0.0, 0.62, 0.67, 0.25, 0.09, 0.58, 0.6, 0.14, 0.39, 0.4, 0.51, 0.1, 0.55, 0.49, 0.37, 0.11, 0.35, 0.62, 0.12, 0.05, 0.43, 0.61, 0.1, 0.39, 0.67, 0.54, 0.03, 0.41, 0.63, 0.18, 0.21, 0.45, 0.6, 0.27, 0.43, 0.5, 0.52, 0.51, 0.56, 0.56, 0.52, 0.51, 0.59, 0.56, 0.47, 0.31, 0.57, 0.52, 0.22, 0.69, 0.71, 0.54, 0.15, 0.45, 0.55, 0.33, 0.55, 0.81, 0.59, 0.72, 0.67, 0.25, 0.65, 0.72, 0.59, 0.32, 0.29, 0.56, 0.53, 0.13, 0.55, 0.61, 0.38, 0.46, 0.45, 0.68, 0.59, 0.56, 0.85, 0.53, 0.9, 0.76, 0.7, 0.59, 0.68, 0.77, 0.88, 0.64, 0.62, 0.79, 0.89, 0.86, 0.8, 0.82, 0.91, 0.56, 0.92, 0.48, 0.55, 0.53, 0.26, 0.72, 0.62, 0.09, 0.24, 0.56, 0.18, 0.76, 0.61, 0.33, 0.47, 0.9, 0.8, 0.89, 0.83, 0.81, 0.86, 0.89, 0.95, 0.98, 1.0, 1.0, 1.0, 0.98, 1.0, 0.9, 1.0, 0.79, 1.0, 0.88, 0.94, 0.99, 0.95, 0.95, 0.99, 0.94, 0.96, 0.99, 0.93, 0.98, 0.96, 0.93, 0.88, 0.96, 0.91, 0.98, 0.92, 1.0, 0.98, 1.0, 1.0, 1.0, 1.0, 0.99, 0.97, 0.99, 0.92, 0.97, 0.86, 0.93, 0.92, 0.86, 0.71, 0.79, 0.72, 0.77, 0.85, 0.91, 0.86, 0.9, 0.83, 0.92, 0.82, 0.82, 0.84, 0.69, 0.95, 0.92, 0.91, 0.97, 0.86, 0.97, 0.88, 0.94, 0.95, 0.92, 0.94, 0.89, 0.99, 0.88, 0.99, 0.96, 1.0, 0.97, 0.99, 1.0, 1.0, 1.0, 0.99, 1.0, 0.99, 1.0, 0.98, 0.99, 0.99, 0.97, 0.98, 0.98, 0.87, 0.88, 0.82, 0.82, 0.89, 0.85, 0.89, 0.89, 0.84, 0.8, 0.91, 0.77, 0.87, 0.89, 0.89, 0.95, 0.94, 0.93, 0.97, 0.97, 0.98, 0.99, 0.91, 0.95, 0.98, 0.92, 0.96, 0.83, 0.89, 0.73, 0.91, 0.76, 0.94, 0.88, 0.97, 0.96, 0.96, 0.97, 0.99, 1.0, 1.0, 1.0, 0.99, 0.83, 0.99, 0.87, 1.0, 1.0, 1.0, 0.98, 1.0, 0.97, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 0.49, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 0.97, 1.0, 0.99, 1.0, 0.98, 0.94, 0.97, 0.84, 0.99, 0.89, 0.97, 0.64, 0.62, 0.61, 0.72, 0.41, 0.55, 0.2, 0.51, 0.51, 0.6, 0.72, 0.85, 0.93, 0.92, 0.92, 1.0, 0.93, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 0.99, 1.0, 0.99, 0.99, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 0.99, 1.0, 0.97, 1.0, 1.0, 1.0, 1.0, 0.99, 1.0, 1.0, 1.0, 0.96, 1.0, 0.94, 1.0, 0.98, 0.96, 0.97, 0.84, 0.93, 0.83, 0.93, 0.91, 1.0, 1.0, 0.93, 0.94, 0.94, 0.96, 1.0, 1.0, 0.99, 1.0, 0.99, 1.0, 1.0, 1.0, 0.99, 0.98, 1.0, 0.98, 1.0, 1.0, 1.0, 1.0, 1.0, 0.99]
null
Component of an E-cadherin/ catenin adhesion complex composed of at least E-cadherin/CDH1, beta-catenin/CTNNB1 or gamma-catenin/JUP, and potentially alpha-catenin/CTNNA1. Forms a ternary complex composed of ADAM10, CADH1 and EPHA4,
null
null
KLRG1, SPEF1, DLGAP5, AJAP1, RAPGEF2, RAB8B, PIP5K1C, PKP2, TRPV4, CTNNB1, CAV1, DDR1, TBC1D2, CTNNA1, JUP, CTNND1, PSEN1, LIMA1, CDH1, JUP, ADAM10, CADH1 , EPHA4,
null
null
null
null
Homodimer
null
79.91949
0.474025
67.126537
0.548218
650
P12830
Q8WWK9
null
degron_data
CDH1
MGPWSRSLSALLLLLQVSSWLCQEPEPCHPGFDAESYTFTVPRRHLERGRVLGRVNFEDCTGRQRTAYFSLDTRFKVGTDGVITVKRPLRFHNPQIHFLVYAWDSTYRKFSTKVTLNTVGHHHRPPPHQASVSGIQAELLTFPNSSPGLRRQKRDWVIPPISCPENEKGPFPKNLVQIKSNKDKEGKVFYSITGQGADTPPVGVFIIERETGWLKVTEPLDRERIATYTLFSHAVSSNGNAVEDPMEILITVTDQNDNKPEFTQEVFKGSVMEGALPGTSVMEVTATDADDDVNTYNAAIAYTILSQDPELPDKNMFTINRNTGVISVVTTGLDRESFPTYTLVVQAADLQGEGLSTTATAVITVTDTNDNPPIFNPTTYKGQVPENEANVVITTLKVTDADAPNTPAWEAVYTILNDDGGQFVVTTNPVNNDGILKTAKGLDFEAKQQYILHVAVTNVVPFEVSLTTSTATVTVDVLDVNEAPIFVPPEKRVEVSEDFGVGQEITSYTAQEPDTFMEQKITYRIWRDTANWLEINPDTGAISTRAELDREDFEHVKNSTYTALIIATDNGSPVATGTGTLLLILSDVNDNAPIPEPRTIFFCERNPKPQVINIIDADLPPNTSPFTAELTHGASANWTIQYNDPTQESIILKPKMALEVGDYKINLKLMDNQNKDQVTTLEVSVCDCEGAAGVCRKAQPVEAGLQIPAILGILGGILALLILILLLLLFLRRRAVVKEPLLPPEDDTRDNVYYYDEEGGGEEDQDFDLSQLHRGLDARPEVTRNDVAPTLMSVPRYLPRPANPDEIGNFIDENLKAADTDPTAPPYDSLLVFDYEGSGSEAASLSSLNSSESDKDQDYDYLNEWGNRFKKLADMYGGGEDD
Homo sapiens
Cell junction, adherens junction, Cell membrane, Endosome, Golgi apparatus, trans-Golgi network, Cytoplasm, Cell junction, desmosome
Tissue enhanced (parathyroid)
{'Ciliated cells': '119.1', 'Basal respiratory cells': '71.1', 'Club cells': '97.3', 'Ionocytes': '81.0', 'Mucus glandular cells': '155.0', 'Serous glandular cells': '67.8', 'Gastric mucus-secreting cells': '133.2', 'Proximal enterocytes': '140.9', 'Paneth cells': '125.1', 'Distal enterocytes': '307.5', 'Intestinal goblet cells': '173.5', 'Exocrine glandular cells': '-0.605', 'Basal prostatic cells': '68.3', 'Prostatic glandular cells': '186.7', 'Breast glandular cells': '0.773', 'Breast myoepithelial cells': '0.700', 'Glandular and luminal cells': '313.0', 'Secretory cells': '82.3', 'Basal keratinocytes': '102.5', 'Suprabasal keratinocytes': '162.6', 'Basal squamous epithelial cells': '51.0', 'Squamous epithelial cells': '106.9', 'Alveolar cells type 1': '0.437', 'Alveolar cells type 2': '0.706', 'Salivary duct cells': '95.9', 'Ductal cells': '0.541', 'Hepatocytes': '0.600', 'Cholangiocytes': '129.7', 'Proximal tubular cells': '0.042', 'Distal tubular cells': '0.0', 'Collecting duct cells': '143.9', 'Mesothelial cells': '0.799', 'Sertoli cells': '0.252', 'Granulosa cells': '12.9', 'Enteroendocrine cells': '92.4', 'Pancreatic endocrine cells': '78.1', 'Leydig cells': '0.264', 'Excitatory neurons': '0.7', 'Inhibitory neurons': '1.3', 'Cone photoreceptor cells': '0.0', 'Rod photoreceptor cells': '0.0', 'Bipolar cells': '0.2', 'Horizontal cells': '0.6', 'Astrocytes': '0.6', 'Oligodendrocyte precursor cells': '0.5', 'Oligodendrocytes': '29.9', 'Microglial cells': '0.9', 'Muller glia cells': '0.1', 'Schwann cells': '0.131', 'Spermatogonia': '0.392', 'Spermatocytes': '0.193', 'Early spermatids': '-0.217', 'Late spermatids': '-0.290', 'Oocytes': '16.9', 'Cytotrophoblasts': '119.2', 'Syncytiotrophoblasts': '45.0', 'Extravillous trophoblasts': '24.9', 'Endothelial cells': '6.1', 'Lymphatic endothelial cells': '0.4', 'Cardiomyocytes': '0.135', 'Skeletal myocytes': '0.107', 'Smooth muscle cells': '5.8', 'Adipocytes': '2.1', 'Melanocytes': '0.335', 'Fibroblasts': '6.5', 'Peritubular cells': '0.210', 'Endometrial stromal cells': '27.7', 'Ovarian stromal cells': '0.7', 'Undifferentiated cells': '101.6', 'T-cells': '2.9', 'B-cells': '4.4', 'Plasma cells': '6.1', 'Nk-cells': '0.0', 'Granulocytes': '8.4', 'Monocytes': '0.0', 'Macrophages': '6.0', 'Hofbauer cells': '4.3', 'Kupffer cells': '1.0', 'Dendritic cells': '5.9', 'Langerhans cells': '0.304', 'Erythroid cells': '0.036', 'Adipocytes (Subcutaneous)': '-0.081', 'Adipocytes (Visceral)': '-0.209', 'Breast glandular cells (progenitors)': '0.538', 'Adipocytes (Breast)': '-0.689', 'Colon enterocytes': '0.790', 'Colon enteroendocrine cells': '0.112', 'Enteric glia cells': '-0.048', 'Mitotic cells (Colon)': '0.299', 'Mitotic cells (Heart)': '0.120', 'Podocytes': '-0.118', 'Ascending Loop of Henle cells': '0.475', 'Intercalated cells': '0.212', 'Cholangiocyte': '0.090', 'NK-cells (Liver)': '-0.005', 'Respiratory ciliated cells': '-0.012', 'Mitotic cells (Lung)': '0.071', 'NK-cells (Lung)': '-0.266', 'B-cells (Lung)': '-0.296', 'Alpha cells': '0.270', 'Beta cells': '0.152', 'Prostate glandular cells': '0.764', 'Prostate basal glandular cells': '0.540', 'Urothelial cells': '0.205', 'Keratinocyte (other)': '0.510', 'Keratinocyte (granular)': '0.055', 'Hair cortex cells': '0.080', 'Inner root sheath cells': '0.131', 'Outer root sheath cells': '0.175', 'Sebaceous gland cells': '0.156', 'Eccrine sweat gland cells': '-0.207', 'Adipocytes (Skin)': '-0.244', 'Mitotic cells (Skin)': '0.442', 'Parietal cells': '0.654', 'Chief cells': '0.649', 'Gastric mucous cells': '0.781', 'Gastric enteroendocrine cells': '0.590', 'Mitotic cells (Stomach)': '0.445', 'Parafollicular cells': '0.173', 'Thyroid glandular cells': '0.865', 'Mitotic cells (Thyroid)': '-0.081', 'Adrenal cortex cells': '0.051', 'Adrenal medulla cells': '0.087', 'Mitotic cells (Adrenal gland)': '0.072', 'Minor salivary glandular cells': '0.371', 'Minor salivary gland ductal cells': '-0.142', 'Minor salivary gland basal cells': '0.582', 'Mitotic cells (Minor salivary gland)': '0.567', 'Adipocytes (Minor salivary gland)': '0.050', 'Somatotropes': '0.121', 'Lactotropes': '0.322', 'Gonadotropes': '0.330', 'Corticotropes': '0.180', 'Thyrotropes': '0.496', 'Undifferentiated cells (Pituitary gland)': '-0.108', 'Mitotic cells (Spleen)': '-0.228', 'Platelets': '-0.050', 'Erythrocytes': '-0.158', 'Hematopoietic stem cells': '-0.211', 'B-cells (Spleen)': '0.266', 'NK-cells (Spleen)': '0.309', 'Amygdala excitatory': '1.0', 'Cerebellar inhibitory': '0.9', 'Cge interneuron': '0.7', 'Deep-layer corticothalamic and 6b': '1.5', 'Deep-layer intratelencephalic': '0.7', 'Deep-layer near-projecting': '0.7', 'Eccentric medium spiny neuron': '0.6', 'Hippocampal ca1-3': '1.9', 'Hippocampal ca4': '1.2', 'Hippocampal dentate gyrus': '1.1', 'Lamp5-lhx6 and chandelier': '0.5', 'Lower rhombic lip': '0.8', 'Mammillary body': '0.6', 'Medium spiny neuron': '0.7', 'Mge interneuron': '1.7', 'Midbrain-derived inhibitory': '0.7', 'Miscellaneous': '0.9', 'Splatter': '3.8', 'Thalamic excitatory': '0.5', 'Upper rhombic lip': '0.8', 'Upper-layer intratelencephalic': '0.6', 'Astrocyte': '4.4', 'Bergmann glia': '0.2', 'Central nervous system macrophage': '0.6', 'Choroid plexus epithelial cell': '52.1', 'Committed oligodendrocyte precursor': '41.5', 'Ependymal cell': '4.8', 'Oligodendrocyte': '53.1', 'Oligodendrocyte precursor cell': '2.4', 'Endothelial cell': '0.7', 'Pericyte': '0.3', 'Vascular associated smooth muscle cell': '0.0', 'Fibroblast': '17.4', 'Leukocyte': '1.1', 'Basophil': '0.0', 'Eosinophil': '0.0', 'Neutrophil': '0.0', 'Classical monocyte': '0.0', 'Non-classical monocyte': '0.0', 'Intermediate monocyte': '0.0', 'T-reg': '2.3', 'GdT-cell': '0.0', 'MAIT T-cell': '0.0', 'Memory CD4 T-cell': '0.0', 'Naive CD4 T-cell': '0.1', 'Memory CD8 T-cell': '0.2', 'Naive CD8 T-cell': '0.3', 'Memory B-cell': '0.0', 'Naive B-cell': '0.1', 'Plasmacytoid DC': '46.6', 'Myeloid DC': '8.5', 'NK-cell': '0.1', 'Total PBMC': '0.7', 'Vd2 gdTCR': '0.0', 'Memory CD4 T-cell Th1\\/Th17': '0.1', 'Memory CD4 T-cell Th17': '0.2', 'Memory CD4 T-cell Th2': '2.9', 'Non-Vd2 gdTCR': '0.1', 'Memory CD4 T-cell Th1': '0.3', 'Memory CD4 T-cell TFH': '0.5', 'Terminal effector memory CD4 T-cell': '0.0', 'Central memory CD8 T-cell': '4.8', 'Effector memory CD8 T-cell': '0.0', 'Terminal effector memory CD8 T-cell': '0.6', 'Non-switched memory B-cell': '0.0', 'Plasmablast': '3.3', 'Switched memory B-cell': '0.0', 'Exhausted memory B-cell': '0.7', 'Progenitor cell': '2.3', 'Memory T-reg': '1.3', 'Naive CD4 T-cell activated': '0.3', 'Naive CD8 T-cell activated': '0.6', 'Naive T-reg': '0.1'}
1O6S, 2O72, 2OMT, 2OMU, 2OMV, 2OMX, 2OMY, 2OMZ, 3FF7, 3FF8, 3L6X, 3L6Y, 4ZT1, 4ZTE, 6CXY, 6OLE, 6OLF, 6OLG, 6VEL, 7STZ, 8H62
{'Adipose Tissue': 1.2125261088039867, 'Adrenal Gland': 0.1914223992248062, 'Bladder': 39.2033519047619, 'Blood': 1.340954264800861, 'Blood Vessel': 0.3121561692883895, 'Brain': 0.8550442199091597, 'Breast': 38.54918344226579, 'Cervix Uteri': 23.539115789473684, 'Colon': 43.41292142490372, 'Esophagus': 53.97513367404844, 'Fallopian Tube': 14.900277777777776, 'Heart': 0.119140469221835, 'Kidney': 25.040449438202245, 'Liver': 26.60802654867257, 'Lung': 35.447986366782004, 'Muscle': 0.1378936151930261, 'Nerve': 17.518468982229404, 'Ovary': 3.6515122222222223, 'Pancreas': 56.89676829268293, 'Pituitary': 24.68741660777385, 'Prostate': 61.279967346938776, 'Salivary Gland': 92.01685185185184, 'Skin': 79.77571720232172, 'Small Intestine': 71.7519320855615, 'Spleen': 10.061029045643156, 'Stomach': 58.07813805013927, 'Testis': 0.8144204986149585, 'Thyroid': 135.176797856049, 'Uterus': 1.442593943661972, 'Vagina': 86.52345512820513}
CKAP2
MSTPAVPQDLQLPPSQRAQSAFKEQRRQKLKEHLLRRKTLFAYKQENEMLSSSRDQRVVTSEDQVQEGTKVLKLKTKMADKENMKRPAESKNNTVVGKHCIPLKPSNELTNSTVVIDTHKPKDSNQTPHLLLTEDDPQSQHMTLSQAFHLKNNSKKKQMTTEKQKQDANMPKKPVLGSYRGQIVQSKINSFRKPLQVKDESSAATKKLSATIPKATKPQPVNTSSVTVKSNRSSNMTATTKFVSTTSQNTQLVRPPIRSHHSNTRDTVKQGISRTSANVTIRKGPHEKELLQSKTALSSVKTSSSQGIIRNKTLSRSIASEVIARPASLSNDKLMEKSEPVDQRRHTAGKAIVDSRSAQPKETSEERKARLSEWKAGKGRVLKRPPNSVVTQHEPAGQNEKPVGSFWTTMAEEDEQRLFTEKVNNTFSECLNLINEGCPKEDILVTLNDLIKNIPDAKKLVKYWICLALIEPITSPIENIIAIYEKAILAGAQPIEEMRHTIVDILTMKSQEKANLGENMEKSCASKEEVKEVSIEDTGVDVDPEKLEMESKLHRNLLFQDCEKEQDNKTKDPTHDVKTPNTETRTSCLIKYNVSTTPYLQSVKKKVQFDGTNSAFKELKFLTPVRRSRRLQEKTSKLPDMLKDHYPCVSSLEQLTELGRETDAFVCRPNAALCRVYYEADTT
Homo sapiens
Cytoplasm, cytoskeleton, Cytoplasm, cytoskeleton, spindle, Cytoplasm, cytoskeleton, spindle pole
Tissue enhanced (bone)
{'Ciliated cells': '7.3', 'Basal respiratory cells': '31.1', 'Club cells': '8.9', 'Ionocytes': '8.1', 'Mucus glandular cells': '7.4', 'Serous glandular cells': '11.9', 'Gastric mucus-secreting cells': '10.6', 'Proximal enterocytes': '5.4', 'Paneth cells': '5.5', 'Distal enterocytes': '4.5', 'Intestinal goblet cells': '10.9', 'Exocrine glandular cells': '-0.217', 'Basal prostatic cells': '3.2', 'Prostatic glandular cells': '4.9', 'Breast glandular cells': '0.050', 'Breast myoepithelial cells': '-0.043', 'Glandular and luminal cells': '10.8', 'Secretory cells': '5.5', 'Basal keratinocytes': '30.8', 'Suprabasal keratinocytes': '23.2', 'Basal squamous epithelial cells': '25.5', 'Squamous epithelial cells': '40.3', 'Alveolar cells type 1': '-0.048', 'Alveolar cells type 2': '0.144', 'Salivary duct cells': '14.8', 'Ductal cells': '0.389', 'Hepatocytes': '0.437', 'Cholangiocytes': '3.8', 'Proximal tubular cells': '0.325', 'Distal tubular cells': '9.2', 'Collecting duct cells': '1.9', 'Mesothelial cells': '0.078', 'Sertoli cells': '0.065', 'Granulosa cells': '39.1', 'Enteroendocrine cells': '6.9', 'Pancreatic endocrine cells': '6.8', 'Leydig cells': '0.064', 'Excitatory neurons': '10.0', 'Inhibitory neurons': '11.9', 'Cone photoreceptor cells': '8.5', 'Rod photoreceptor cells': '6.0', 'Bipolar cells': '13.3', 'Horizontal cells': '6.3', 'Astrocytes': '5.0', 'Oligodendrocyte precursor cells': '3.3', 'Oligodendrocytes': '1.9', 'Microglial cells': '6.3', 'Muller glia cells': '11.0', 'Schwann cells': '0.139', 'Spermatogonia': '0.504', 'Spermatocytes': '0.871', 'Early spermatids': '0.400', 'Late spermatids': '-0.047', 'Oocytes': '50.7', 'Cytotrophoblasts': '44.8', 'Syncytiotrophoblasts': '11.1', 'Extravillous trophoblasts': '38.2', 'Endothelial cells': '11.1', 'Lymphatic endothelial cells': '15.9', 'Cardiomyocytes': '0.620', 'Skeletal myocytes': '0.065', 'Smooth muscle cells': '7.7', 'Adipocytes': '7.5', 'Melanocytes': '0.527', 'Fibroblasts': '9.9', 'Peritubular cells': '-0.015', 'Endometrial stromal cells': '15.2', 'Ovarian stromal cells': '6.4', 'Undifferentiated cells': '33.2', 'T-cells': '27.9', 'B-cells': '32.6', 'Plasma cells': '32.5', 'Nk-cells': '16.9', 'Granulocytes': '12.8', 'Monocytes': '15.2', 'Macrophages': '19.3', 'Hofbauer cells': '25.5', 'Kupffer cells': '19.6', 'Dendritic cells': '31.5', 'Langerhans cells': '0.286', 'Erythroid cells': '0.006', 'Adipocytes (Subcutaneous)': '0.153', 'Adipocytes (Visceral)': '0.014', 'Breast glandular cells (progenitors)': '0.113', 'Adipocytes (Breast)': '0.151', 'Colon enterocytes': '0.150', 'Colon enteroendocrine cells': '0.052', 'Enteric glia cells': '-0.196', 'Mitotic cells (Colon)': '0.287', 'Mitotic cells (Heart)': '0.530', 'Podocytes': '-0.090', 'Ascending Loop of Henle cells': '0.414', 'Intercalated cells': '0.038', 'Cholangiocyte': '0.272', 'NK-cells (Liver)': '-0.079', 'Respiratory ciliated cells': '0.030', 'Mitotic cells (Lung)': '0.635', 'NK-cells (Lung)': '-0.042', 'B-cells (Lung)': '-0.028', 'Alpha cells': '0.293', 'Beta cells': '0.121', 'Prostate glandular cells': '0.036', 'Prostate basal glandular cells': '0.298', 'Urothelial cells': '0.203', 'Keratinocyte (other)': '0.411', 'Keratinocyte (granular)': '-0.018', 'Hair cortex cells': '-0.076', 'Inner root sheath cells': '0.061', 'Outer root sheath cells': '0.120', 'Sebaceous gland cells': '0.121', 'Eccrine sweat gland cells': '-0.116', 'Adipocytes (Skin)': '-0.210', 'Mitotic cells (Skin)': '0.732', 'Parietal cells': '-0.443', 'Chief cells': '-0.433', 'Gastric mucous cells': '0.015', 'Gastric enteroendocrine cells': '-0.280', 'Mitotic cells (Stomach)': '0.537', 'Parafollicular cells': '0.037', 'Thyroid glandular cells': '0.256', 'Mitotic cells (Thyroid)': '0.321', 'Adrenal cortex cells': '0.616', 'Adrenal medulla cells': '0.076', 'Mitotic cells (Adrenal gland)': '0.595', 'Minor salivary glandular cells': '0.050', 'Minor salivary gland ductal cells': '-0.219', 'Minor salivary gland basal cells': '0.700', 'Mitotic cells (Minor salivary gland)': '0.764', 'Adipocytes (Minor salivary gland)': '0.165', 'Somatotropes': '0.009', 'Lactotropes': '0.343', 'Gonadotropes': '0.268', 'Corticotropes': '0.275', 'Thyrotropes': '0.329', 'Undifferentiated cells (Pituitary gland)': '-0.012', 'Mitotic cells (Spleen)': '0.621', 'Platelets': '0.094', 'Erythrocytes': '0.132', 'Hematopoietic stem cells': '0.197', 'B-cells (Spleen)': '0.050', 'NK-cells (Spleen)': '0.038', 'Amygdala excitatory': '14.4', 'Cerebellar inhibitory': '28.4', 'Cge interneuron': '23.5', 'Deep-layer corticothalamic and 6b': '14.9', 'Deep-layer intratelencephalic': '13.3', 'Deep-layer near-projecting': '18.4', 'Eccentric medium spiny neuron': '14.3', 'Hippocampal ca1-3': '16.4', 'Hippocampal ca4': '19.5', 'Hippocampal dentate gyrus': '25.2', 'Lamp5-lhx6 and chandelier': '22.5', 'Lower rhombic lip': '39.3', 'Mammillary body': '22.7', 'Medium spiny neuron': '16.0', 'Mge interneuron': '19.9', 'Midbrain-derived inhibitory': '23.0', 'Miscellaneous': '14.9', 'Splatter': '25.4', 'Thalamic excitatory': '22.6', 'Upper rhombic lip': '33.1', 'Upper-layer intratelencephalic': '12.0', 'Astrocyte': '10.6', 'Bergmann glia': '6.2', 'Central nervous system macrophage': '19.9', 'Choroid plexus epithelial cell': '12.2', 'Committed oligodendrocyte precursor': '12.7', 'Ependymal cell': '4.2', 'Oligodendrocyte': '5.2', 'Oligodendrocyte precursor cell': '17.3', 'Endothelial cell': '11.6', 'Pericyte': '5.8', 'Vascular associated smooth muscle cell': '3.1', 'Fibroblast': '6.2', 'Leukocyte': '16.0', 'Basophil': '52.8', 'Eosinophil': '22.0', 'Neutrophil': '9.4', 'Classical monocyte': '18.6', 'Non-classical monocyte': '46.3', 'Intermediate monocyte': '48.9', 'T-reg': '41.4', 'GdT-cell': '10.3', 'MAIT T-cell': '17.2', 'Memory CD4 T-cell': '15.7', 'Naive CD4 T-cell': '37.2', 'Memory CD8 T-cell': '12.8', 'Naive CD8 T-cell': '27.2', 'Memory B-cell': '25.4', 'Naive B-cell': '50.3', 'Plasmacytoid DC': '49.8', 'Myeloid DC': '41.7', 'NK-cell': '13.4', 'Total PBMC': '28.5', 'Vd2 gdTCR': '26.2', 'Memory CD4 T-cell Th1\\/Th17': '32.4', 'Memory CD4 T-cell Th17': '29.6', 'Memory CD4 T-cell Th2': '33.8', 'Non-Vd2 gdTCR': '18.4', 'Memory CD4 T-cell Th1': '29.3', 'Memory CD4 T-cell TFH': '28.5', 'Terminal effector memory CD4 T-cell': '22.5', 'Central memory CD8 T-cell': '29.6', 'Effector memory CD8 T-cell': '36.2', 'Terminal effector memory CD8 T-cell': '20.7', 'Non-switched memory B-cell': '34.8', 'Plasmablast': '68.8', 'Switched memory B-cell': '33.4', 'Exhausted memory B-cell': '32.5', 'Progenitor cell': '66.8', 'Memory T-reg': '30.6', 'Naive CD4 T-cell activated': '10.0', 'Naive CD8 T-cell activated': '10.3', 'Naive T-reg': '34.5'}
null
{'Adipose Tissue': 4.280651976744187, 'Adrenal Gland': 7.484100387596899, 'Bladder': 5.046142857142857, 'Blood': 10.339545209903122, 'Blood Vessel': 3.654278951310862, 'Brain': 5.928422823618471, 'Breast': 3.9675289760348584, 'Cervix Uteri': 4.338315789473684, 'Colon': 4.377415789473684, 'Esophagus': 6.548149134948098, 'Fallopian Tube': 3.0292222222222223, 'Heart': 1.8164202787456445, 'Kidney': 2.3842370786516853, 'Liver': 1.4220862831858407, 'Lung': 5.353738062283737, 'Muscle': 2.016712391033624, 'Nerve': 4.852846526655896, 'Ovary': 3.9144055555555552, 'Pancreas': 0.919306493902439, 'Pituitary': 7.795000000000001, 'Prostate': 4.071029795918367, 'Salivary Gland': 5.9194506172839505, 'Skin': 20.163732448866774, 'Small Intestine': 6.9891016042780745, 'Spleen': 8.95429460580913, 'Stomach': 2.773699164345404, 'Testis': 27.759362880886425, 'Thyroid': 4.374940275650842, 'Uterus': 3.97512676056338, 'Vagina': 8.247121794871795}
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null
Component of an E-cadherin/ catenin adhesion complex composed of at least E-cadherin/CDH1, beta-catenin/CTNNB1 or gamma-catenin/JUP, and potentially alpha-catenin/CTNNA1. Forms a ternary complex composed of ADAM10, CADH1 and EPHA4,
null
null
KLRG1, SPEF1, DLGAP5, AJAP1, RAPGEF2, RAB8B, PIP5K1C, PKP2, TRPV4, CTNNB1, CAV1, DDR1, TBC1D2, CTNNA1, JUP, CTNND1, PSEN1, LIMA1, CDH1, JUP, ADAM10, CADH1 , EPHA4,
null
null
null
null
Homodimer
null
79.91949
0.474025
59.060937
0.738302
1,063
P12830
Q8WWK9-4
null
degron_data
CDH1
MGPWSRSLSALLLLLQVSSWLCQEPEPCHPGFDAESYTFTVPRRHLERGRVLGRVNFEDCTGRQRTAYFSLDTRFKVGTDGVITVKRPLRFHNPQIHFLVYAWDSTYRKFSTKVTLNTVGHHHRPPPHQASVSGIQAELLTFPNSSPGLRRQKRDWVIPPISCPENEKGPFPKNLVQIKSNKDKEGKVFYSITGQGADTPPVGVFIIERETGWLKVTEPLDRERIATYTLFSHAVSSNGNAVEDPMEILITVTDQNDNKPEFTQEVFKGSVMEGALPGTSVMEVTATDADDDVNTYNAAIAYTILSQDPELPDKNMFTINRNTGVISVVTTGLDRESFPTYTLVVQAADLQGEGLSTTATAVITVTDTNDNPPIFNPTTYKGQVPENEANVVITTLKVTDADAPNTPAWEAVYTILNDDGGQFVVTTNPVNNDGILKTAKGLDFEAKQQYILHVAVTNVVPFEVSLTTSTATVTVDVLDVNEAPIFVPPEKRVEVSEDFGVGQEITSYTAQEPDTFMEQKITYRIWRDTANWLEINPDTGAISTRAELDREDFEHVKNSTYTALIIATDNGSPVATGTGTLLLILSDVNDNAPIPEPRTIFFCERNPKPQVINIIDADLPPNTSPFTAELTHGASANWTIQYNDPTQESIILKPKMALEVGDYKINLKLMDNQNKDQVTTLEVSVCDCEGAAGVCRKAQPVEAGLQIPAILGILGGILALLILILLLLLFLRRRAVVKEPLLPPEDDTRDNVYYYDEEGGGEEDQDFDLSQLHRGLDARPEVTRNDVAPTLMSVPRYLPRPANPDEIGNFIDENLKAADTDPTAPPYDSLLVFDYEGSGSEAASLSSLNSSESDKDQDYDYLNEWGNRFKKLADMYGGGEDD
Homo sapiens
Cell junction, adherens junction, Cell membrane, Endosome, Golgi apparatus, trans-Golgi network, Cytoplasm, Cell junction, desmosome
Tissue enhanced (parathyroid)
{'Ciliated cells': '119.1', 'Basal respiratory cells': '71.1', 'Club cells': '97.3', 'Ionocytes': '81.0', 'Mucus glandular cells': '155.0', 'Serous glandular cells': '67.8', 'Gastric mucus-secreting cells': '133.2', 'Proximal enterocytes': '140.9', 'Paneth cells': '125.1', 'Distal enterocytes': '307.5', 'Intestinal goblet cells': '173.5', 'Exocrine glandular cells': '-0.605', 'Basal prostatic cells': '68.3', 'Prostatic glandular cells': '186.7', 'Breast glandular cells': '0.773', 'Breast myoepithelial cells': '0.700', 'Glandular and luminal cells': '313.0', 'Secretory cells': '82.3', 'Basal keratinocytes': '102.5', 'Suprabasal keratinocytes': '162.6', 'Basal squamous epithelial cells': '51.0', 'Squamous epithelial cells': '106.9', 'Alveolar cells type 1': '0.437', 'Alveolar cells type 2': '0.706', 'Salivary duct cells': '95.9', 'Ductal cells': '0.541', 'Hepatocytes': '0.600', 'Cholangiocytes': '129.7', 'Proximal tubular cells': '0.042', 'Distal tubular cells': '0.0', 'Collecting duct cells': '143.9', 'Mesothelial cells': '0.799', 'Sertoli cells': '0.252', 'Granulosa cells': '12.9', 'Enteroendocrine cells': '92.4', 'Pancreatic endocrine cells': '78.1', 'Leydig cells': '0.264', 'Excitatory neurons': '0.7', 'Inhibitory neurons': '1.3', 'Cone photoreceptor cells': '0.0', 'Rod photoreceptor cells': '0.0', 'Bipolar cells': '0.2', 'Horizontal cells': '0.6', 'Astrocytes': '0.6', 'Oligodendrocyte precursor cells': '0.5', 'Oligodendrocytes': '29.9', 'Microglial cells': '0.9', 'Muller glia cells': '0.1', 'Schwann cells': '0.131', 'Spermatogonia': '0.392', 'Spermatocytes': '0.193', 'Early spermatids': '-0.217', 'Late spermatids': '-0.290', 'Oocytes': '16.9', 'Cytotrophoblasts': '119.2', 'Syncytiotrophoblasts': '45.0', 'Extravillous trophoblasts': '24.9', 'Endothelial cells': '6.1', 'Lymphatic endothelial cells': '0.4', 'Cardiomyocytes': '0.135', 'Skeletal myocytes': '0.107', 'Smooth muscle cells': '5.8', 'Adipocytes': '2.1', 'Melanocytes': '0.335', 'Fibroblasts': '6.5', 'Peritubular cells': '0.210', 'Endometrial stromal cells': '27.7', 'Ovarian stromal cells': '0.7', 'Undifferentiated cells': '101.6', 'T-cells': '2.9', 'B-cells': '4.4', 'Plasma cells': '6.1', 'Nk-cells': '0.0', 'Granulocytes': '8.4', 'Monocytes': '0.0', 'Macrophages': '6.0', 'Hofbauer cells': '4.3', 'Kupffer cells': '1.0', 'Dendritic cells': '5.9', 'Langerhans cells': '0.304', 'Erythroid cells': '0.036', 'Adipocytes (Subcutaneous)': '-0.081', 'Adipocytes (Visceral)': '-0.209', 'Breast glandular cells (progenitors)': '0.538', 'Adipocytes (Breast)': '-0.689', 'Colon enterocytes': '0.790', 'Colon enteroendocrine cells': '0.112', 'Enteric glia cells': '-0.048', 'Mitotic cells (Colon)': '0.299', 'Mitotic cells (Heart)': '0.120', 'Podocytes': '-0.118', 'Ascending Loop of Henle cells': '0.475', 'Intercalated cells': '0.212', 'Cholangiocyte': '0.090', 'NK-cells (Liver)': '-0.005', 'Respiratory ciliated cells': '-0.012', 'Mitotic cells (Lung)': '0.071', 'NK-cells (Lung)': '-0.266', 'B-cells (Lung)': '-0.296', 'Alpha cells': '0.270', 'Beta cells': '0.152', 'Prostate glandular cells': '0.764', 'Prostate basal glandular cells': '0.540', 'Urothelial cells': '0.205', 'Keratinocyte (other)': '0.510', 'Keratinocyte (granular)': '0.055', 'Hair cortex cells': '0.080', 'Inner root sheath cells': '0.131', 'Outer root sheath cells': '0.175', 'Sebaceous gland cells': '0.156', 'Eccrine sweat gland cells': '-0.207', 'Adipocytes (Skin)': '-0.244', 'Mitotic cells (Skin)': '0.442', 'Parietal cells': '0.654', 'Chief cells': '0.649', 'Gastric mucous cells': '0.781', 'Gastric enteroendocrine cells': '0.590', 'Mitotic cells (Stomach)': '0.445', 'Parafollicular cells': '0.173', 'Thyroid glandular cells': '0.865', 'Mitotic cells (Thyroid)': '-0.081', 'Adrenal cortex cells': '0.051', 'Adrenal medulla cells': '0.087', 'Mitotic cells (Adrenal gland)': '0.072', 'Minor salivary glandular cells': '0.371', 'Minor salivary gland ductal cells': '-0.142', 'Minor salivary gland basal cells': '0.582', 'Mitotic cells (Minor salivary gland)': '0.567', 'Adipocytes (Minor salivary gland)': '0.050', 'Somatotropes': '0.121', 'Lactotropes': '0.322', 'Gonadotropes': '0.330', 'Corticotropes': '0.180', 'Thyrotropes': '0.496', 'Undifferentiated cells (Pituitary gland)': '-0.108', 'Mitotic cells (Spleen)': '-0.228', 'Platelets': '-0.050', 'Erythrocytes': '-0.158', 'Hematopoietic stem cells': '-0.211', 'B-cells (Spleen)': '0.266', 'NK-cells (Spleen)': '0.309', 'Amygdala excitatory': '1.0', 'Cerebellar inhibitory': '0.9', 'Cge interneuron': '0.7', 'Deep-layer corticothalamic and 6b': '1.5', 'Deep-layer intratelencephalic': '0.7', 'Deep-layer near-projecting': '0.7', 'Eccentric medium spiny neuron': '0.6', 'Hippocampal ca1-3': '1.9', 'Hippocampal ca4': '1.2', 'Hippocampal dentate gyrus': '1.1', 'Lamp5-lhx6 and chandelier': '0.5', 'Lower rhombic lip': '0.8', 'Mammillary body': '0.6', 'Medium spiny neuron': '0.7', 'Mge interneuron': '1.7', 'Midbrain-derived inhibitory': '0.7', 'Miscellaneous': '0.9', 'Splatter': '3.8', 'Thalamic excitatory': '0.5', 'Upper rhombic lip': '0.8', 'Upper-layer intratelencephalic': '0.6', 'Astrocyte': '4.4', 'Bergmann glia': '0.2', 'Central nervous system macrophage': '0.6', 'Choroid plexus epithelial cell': '52.1', 'Committed oligodendrocyte precursor': '41.5', 'Ependymal cell': '4.8', 'Oligodendrocyte': '53.1', 'Oligodendrocyte precursor cell': '2.4', 'Endothelial cell': '0.7', 'Pericyte': '0.3', 'Vascular associated smooth muscle cell': '0.0', 'Fibroblast': '17.4', 'Leukocyte': '1.1', 'Basophil': '0.0', 'Eosinophil': '0.0', 'Neutrophil': '0.0', 'Classical monocyte': '0.0', 'Non-classical monocyte': '0.0', 'Intermediate monocyte': '0.0', 'T-reg': '2.3', 'GdT-cell': '0.0', 'MAIT T-cell': '0.0', 'Memory CD4 T-cell': '0.0', 'Naive CD4 T-cell': '0.1', 'Memory CD8 T-cell': '0.2', 'Naive CD8 T-cell': '0.3', 'Memory B-cell': '0.0', 'Naive B-cell': '0.1', 'Plasmacytoid DC': '46.6', 'Myeloid DC': '8.5', 'NK-cell': '0.1', 'Total PBMC': '0.7', 'Vd2 gdTCR': '0.0', 'Memory CD4 T-cell Th1\\/Th17': '0.1', 'Memory CD4 T-cell Th17': '0.2', 'Memory CD4 T-cell Th2': '2.9', 'Non-Vd2 gdTCR': '0.1', 'Memory CD4 T-cell Th1': '0.3', 'Memory CD4 T-cell TFH': '0.5', 'Terminal effector memory CD4 T-cell': '0.0', 'Central memory CD8 T-cell': '4.8', 'Effector memory CD8 T-cell': '0.0', 'Terminal effector memory CD8 T-cell': '0.6', 'Non-switched memory B-cell': '0.0', 'Plasmablast': '3.3', 'Switched memory B-cell': '0.0', 'Exhausted memory B-cell': '0.7', 'Progenitor cell': '2.3', 'Memory T-reg': '1.3', 'Naive CD4 T-cell activated': '0.3', 'Naive CD8 T-cell activated': '0.6', 'Naive T-reg': '0.1'}
1O6S, 2O72, 2OMT, 2OMU, 2OMV, 2OMX, 2OMY, 2OMZ, 3FF7, 3FF8, 3L6X, 3L6Y, 4ZT1, 4ZTE, 6CXY, 6OLE, 6OLF, 6OLG, 6VEL, 7STZ, 8H62
{'Adipose Tissue': 1.2125261088039867, 'Adrenal Gland': 0.1914223992248062, 'Bladder': 39.2033519047619, 'Blood': 1.340954264800861, 'Blood Vessel': 0.3121561692883895, 'Brain': 0.8550442199091597, 'Breast': 38.54918344226579, 'Cervix Uteri': 23.539115789473684, 'Colon': 43.41292142490372, 'Esophagus': 53.97513367404844, 'Fallopian Tube': 14.900277777777776, 'Heart': 0.119140469221835, 'Kidney': 25.040449438202245, 'Liver': 26.60802654867257, 'Lung': 35.447986366782004, 'Muscle': 0.1378936151930261, 'Nerve': 17.518468982229404, 'Ovary': 3.6515122222222223, 'Pancreas': 56.89676829268293, 'Pituitary': 24.68741660777385, 'Prostate': 61.279967346938776, 'Salivary Gland': 92.01685185185184, 'Skin': 79.77571720232172, 'Small Intestine': 71.7519320855615, 'Spleen': 10.061029045643156, 'Stomach': 58.07813805013927, 'Testis': 0.8144204986149585, 'Thyroid': 135.176797856049, 'Uterus': 1.442593943661972, 'Vagina': 86.52345512820513}
CKAP2
MSTPAVPQDLQLPPSQRAQSAFKEQRRQKLKEHLLRRKTLFAYKQENEMLSSRDQRVVTSEDQVQEGTKVLKLKTKMADKENMKRPAESKNNTVVGKHCIPLKPSNELTNSTVVIDTHKPKDSNQTPHLLLTEDDPQSQHMTLSQAFHLKNNSKKKQMTTEKQKQDANMPKKPVLGSYRGQIVQSKINSFRKPLQVKDESSAATKKLSATIPKATKPQPVNTSSVTVKSNRSSNMTATTKFVSTTSQNTQLVRPPIRSHHSNTRDTVKQGISRTSANVTIRKGPHEKELLQSKTALSSVKTSSSQGIIRNKTLSRSIASEVIARPASLSNDKLMEKSEPVDQRRHTAGKAIVDSRSAQPKETSEERKARLSEWKAGKGRVLKRPPNSVVTQHEPAGQNEKPVGSFWTTMAEEDEQRLFTEKVNNTFSECLNLINEGCPKEDILVTLNDLIKNIPDAKKLVKYWICLALIEPITSPIENIIAIYEKAILAGAQVR
Homo sapiens
null
Not found
{}
null
{'Adipose Tissue': 4.280651976744187, 'Adrenal Gland': 7.484100387596899, 'Bladder': 5.046142857142857, 'Blood': 10.339545209903122, 'Blood Vessel': 3.654278951310862, 'Brain': 5.928422823618471, 'Breast': 3.9675289760348584, 'Cervix Uteri': 4.338315789473684, 'Colon': 4.377415789473684, 'Esophagus': 6.548149134948098, 'Fallopian Tube': 3.0292222222222223, 'Heart': 1.8164202787456445, 'Kidney': 2.3842370786516853, 'Liver': 1.4220862831858407, 'Lung': 5.353738062283737, 'Muscle': 2.016712391033624, 'Nerve': 4.852846526655896, 'Ovary': 3.9144055555555552, 'Pancreas': 0.919306493902439, 'Pituitary': 7.795000000000001, 'Prostate': 4.071029795918367, 'Salivary Gland': 5.9194506172839505, 'Skin': 20.163732448866774, 'Small Intestine': 6.9891016042780745, 'Spleen': 8.95429460580913, 'Stomach': 2.773699164345404, 'Testis': 27.759362880886425, 'Thyroid': 4.374940275650842, 'Uterus': 3.97512676056338, 'Vagina': 8.247121794871795}
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0.32, 0.01, 0.22, 0.0, 0.05, 0.0, 0.41, 0.46, 0.42, 0.82, 0.48, 0.4, 0.5, 0.17, 0.62, 0.06, 0.32, 0.0, 0.25, 0.0, 0.42, 0.08, 0.41, 0.27, 0.16, 0.04, 0.36, 0.32, 0.2, 0.0, 0.52, 0.04, 0.66, 0.47, 0.52, 0.78, 0.09, 0.77, 0.08, 0.6, 0.0, 0.31, 0.03, 0.58, 0.47, 0.59, 0.44, 0.23, 0.54, 0.1, 0.18, 0.45, 0.0, 0.53, 0.11, 0.59, 0.17, 0.51, 0.01, 0.19, 0.71, 0.77, 0.3, 0.44, 0.08, 0.14, 0.52, 0.05, 0.37, 0.1, 0.42, 0.23, 0.61, 0.43, 0.22, 0.96, 0.54, 0.4, 0.3, 0.07, 0.39, 0.17, 0.43, 0.38, 0.3, 0.8, 0.83, 0.44, 0.03, 0.11, 0.0, 0.23, 0.0, 0.31, 0.0, 0.38, 0.58, 0.51, 0.01, 0.49, 0.13, 0.26, 0.69, 0.46, 0.41, 0.51, 0.06, 0.51, 0.03, 0.38, 0.0, 0.06, 0.0, 0.34, 0.08, 0.53, 0.42, 0.88, 0.25, 0.75, 0.49, 1.0, 0.34, 0.86, 0.48, 0.18, 0.52, 0.01, 0.32, 0.0, 0.19, 0.0, 0.3, 0.05, 0.44, 0.27, 0.43, 0.11, 0.31, 0.39, 0.03, 0.55, 0.04, 0.52, 0.51, 0.64, 0.57, 0.19, 0.68, 0.13, 0.84, 0.06, 0.31, 0.07, 0.69, 0.26, 0.37, 0.53, 0.67, 0.5, 0.56, 0.14, 0.18, 0.47, 0.01, 0.47, 0.15, 0.61, 0.28, 0.2, 0.02, 0.76, 0.55, 0.31, 0.94, 0.22, 0.57, 0.17, 0.4, 0.07, 0.5, 0.31, 0.7, 0.2, 0.14, 0.3, 0.23, 0.58, 0.07, 0.06, 0.55, 0.15, 0.46, 0.43, 0.64, 0.53, 0.0, 0.18, 0.01, 0.23, 0.02, 0.63, 0.33, 0.79, 0.06, 0.38, 0.07, 0.14, 0.23, 0.68, 0.89, 0.29, 0.06, 0.72, 0.92, 0.24, 0.25, 0.0, 0.46, 0.02, 0.21, 0.01, 0.06, 0.0, 0.05, 0.07, 0.61, 0.17, 0.89, 0.72, 0.66, 0.14, 0.52, 0.07, 0.58, 0.01, 0.26, 0.0, 0.13, 0.0, 0.29, 0.04, 0.46, 0.27, 0.28, 0.23, 0.56, 0.32, 0.25, 0.0, 0.33, 0.05, 0.55, 0.5, 0.58, 0.53, 0.04, 0.27, 0.02, 0.04, 0.37, 0.67, 0.74, 0.35, 0.62, 0.54, 0.26, 0.46, 0.0, 0.47, 0.09, 0.45, 0.15, 0.39, 0.05, 0.44, 0.85, 0.56, 0.11, 0.11, 0.35, 0.42, 0.03, 0.32, 0.12, 0.49, 0.19, 0.25, 0.8, 0.6, 0.09, 0.49, 0.57, 0.36, 0.04, 0.35, 0.28, 0.52, 0.39, 0.5, 0.28, 0.93, 0.47, 0.3, 0.47, 0.08, 0.02, 0.18, 0.01, 0.34, 0.23, 0.55, 0.57, 0.91, 0.1, 0.78, 0.52, 0.34, 0.61, 0.24, 0.75, 0.0, 0.2, 0.02, 0.24, 0.0, 0.18, 0.04, 0.44, 0.59, 0.71, 0.29, 0.52, 0.37, 0.5, 0.11, 0.6, 0.02, 0.48, 0.01, 0.16, 0.04, 0.35, 0.66, 0.47, 0.74, 0.14, 0.62, 0.16, 0.77, 0.79, 0.27, 0.93, 0.69, 0.88, 0.88, 0.85, 0.87, 0.91, 0.92, 0.82, 0.63, 0.75, 0.7, 0.7, 0.38, 0.43, 0.64, 0.55, 0.54, 0.59, 0.45, 0.47, 0.5, 0.58, 0.52, 0.61, 0.57, 0.52, 0.68, 0.44, 0.6, 0.61, 0.58, 0.55, 0.5, 0.61, 0.61, 0.86, 0.86, 0.75, 0.91, 0.96, 0.93, 1.0, 0.87, 0.97, 0.91, 0.95, 0.86, 0.98, 0.93, 0.88, 0.59, 0.87, 0.7, 0.67, 0.85, 0.89, 0.88, 0.91, 0.93, 0.88, 0.99, 0.92, 1.0, 0.79, 0.9, 1.0, 0.94, 1.0, 0.97, 0.96, 0.9, 0.63, 0.68, 0.48, 0.54, 0.8, 0.7, 0.7, 0.95, 0.87, 0.77, 0.84, 0.79, 0.89, 0.95, 0.8, 0.77, 0.51, 0.87, 0.7, 0.52, 0.84, 0.91, 0.51, 0.96, 0.79, 0.92, 0.84, 0.21, 0.89, 0.53, 0.52, 0.89, 0.86, 0.26, 0.91, 0.45, 0.68, 0.84, 0.48, 0.44, 0.51, 0.62, 0.28, 0.59, 0.63, 0.57, 0.15, 0.55, 0.66, 0.1, 0.38, 0.74, 0.65, 0.17, 0.43, 0.66, 0.41, 0.8, 0.75, 0.9, 0.93, 0.52, 0.76, 0.89, 0.87, 0.76, 0.92, 0.91, 0.75, 0.61, 0.96, 0.89, 0.73, 0.97, 0.68, 0.87, 0.55, 0.85, 0.77, 0.69, 0.76, 0.98, 0.83, 0.68, 0.82, 0.74, 0.65, 0.96, 0.93, 0.54, 0.64, 0.28, 0.54, 0.52, 0.16, 0.51, 0.88, 0.6, 0.4, 0.88, 0.95, 0.33, 0.56, 0.73, 0.39, 0.06, 0.61, 0.75, 0.47, 0.19, 0.87, 0.7, 0.97, 0.94, 0.97]
null
null
null
Component of an E-cadherin/ catenin adhesion complex composed of at least E-cadherin/CDH1, beta-catenin/CTNNB1 or gamma-catenin/JUP, and potentially alpha-catenin/CTNNA1. Forms a ternary complex composed of ADAM10, CADH1 and EPHA4,
null
null
KLRG1, SPEF1, DLGAP5, AJAP1, RAPGEF2, RAB8B, PIP5K1C, PKP2, TRPV4, CTNNB1, CAV1, DDR1, TBC1D2, CTNNA1, JUP, CTNND1, PSEN1, LIMA1, CDH1, JUP, ADAM10, CADH1 , EPHA4,
null
null
null
null
Homodimer
null
79.91949
0.474025
null
null
1,063
P12830
Q8WWK9-5
null
degron_data
CDH1
MGPWSRSLSALLLLLQVSSWLCQEPEPCHPGFDAESYTFTVPRRHLERGRVLGRVNFEDCTGRQRTAYFSLDTRFKVGTDGVITVKRPLRFHNPQIHFLVYAWDSTYRKFSTKVTLNTVGHHHRPPPHQASVSGIQAELLTFPNSSPGLRRQKRDWVIPPISCPENEKGPFPKNLVQIKSNKDKEGKVFYSITGQGADTPPVGVFIIERETGWLKVTEPLDRERIATYTLFSHAVSSNGNAVEDPMEILITVTDQNDNKPEFTQEVFKGSVMEGALPGTSVMEVTATDADDDVNTYNAAIAYTILSQDPELPDKNMFTINRNTGVISVVTTGLDRESFPTYTLVVQAADLQGEGLSTTATAVITVTDTNDNPPIFNPTTYKGQVPENEANVVITTLKVTDADAPNTPAWEAVYTILNDDGGQFVVTTNPVNNDGILKTAKGLDFEAKQQYILHVAVTNVVPFEVSLTTSTATVTVDVLDVNEAPIFVPPEKRVEVSEDFGVGQEITSYTAQEPDTFMEQKITYRIWRDTANWLEINPDTGAISTRAELDREDFEHVKNSTYTALIIATDNGSPVATGTGTLLLILSDVNDNAPIPEPRTIFFCERNPKPQVINIIDADLPPNTSPFTAELTHGASANWTIQYNDPTQESIILKPKMALEVGDYKINLKLMDNQNKDQVTTLEVSVCDCEGAAGVCRKAQPVEAGLQIPAILGILGGILALLILILLLLLFLRRRAVVKEPLLPPEDDTRDNVYYYDEEGGGEEDQDFDLSQLHRGLDARPEVTRNDVAPTLMSVPRYLPRPANPDEIGNFIDENLKAADTDPTAPPYDSLLVFDYEGSGSEAASLSSLNSSESDKDQDYDYLNEWGNRFKKLADMYGGGEDD
Homo sapiens
Cell junction, adherens junction, Cell membrane, Endosome, Golgi apparatus, trans-Golgi network, Cytoplasm, Cell junction, desmosome
Tissue enhanced (parathyroid)
{'Ciliated cells': '119.1', 'Basal respiratory cells': '71.1', 'Club cells': '97.3', 'Ionocytes': '81.0', 'Mucus glandular cells': '155.0', 'Serous glandular cells': '67.8', 'Gastric mucus-secreting cells': '133.2', 'Proximal enterocytes': '140.9', 'Paneth cells': '125.1', 'Distal enterocytes': '307.5', 'Intestinal goblet cells': '173.5', 'Exocrine glandular cells': '-0.605', 'Basal prostatic cells': '68.3', 'Prostatic glandular cells': '186.7', 'Breast glandular cells': '0.773', 'Breast myoepithelial cells': '0.700', 'Glandular and luminal cells': '313.0', 'Secretory cells': '82.3', 'Basal keratinocytes': '102.5', 'Suprabasal keratinocytes': '162.6', 'Basal squamous epithelial cells': '51.0', 'Squamous epithelial cells': '106.9', 'Alveolar cells type 1': '0.437', 'Alveolar cells type 2': '0.706', 'Salivary duct cells': '95.9', 'Ductal cells': '0.541', 'Hepatocytes': '0.600', 'Cholangiocytes': '129.7', 'Proximal tubular cells': '0.042', 'Distal tubular cells': '0.0', 'Collecting duct cells': '143.9', 'Mesothelial cells': '0.799', 'Sertoli cells': '0.252', 'Granulosa cells': '12.9', 'Enteroendocrine cells': '92.4', 'Pancreatic endocrine cells': '78.1', 'Leydig cells': '0.264', 'Excitatory neurons': '0.7', 'Inhibitory neurons': '1.3', 'Cone photoreceptor cells': '0.0', 'Rod photoreceptor cells': '0.0', 'Bipolar cells': '0.2', 'Horizontal cells': '0.6', 'Astrocytes': '0.6', 'Oligodendrocyte precursor cells': '0.5', 'Oligodendrocytes': '29.9', 'Microglial cells': '0.9', 'Muller glia cells': '0.1', 'Schwann cells': '0.131', 'Spermatogonia': '0.392', 'Spermatocytes': '0.193', 'Early spermatids': '-0.217', 'Late spermatids': '-0.290', 'Oocytes': '16.9', 'Cytotrophoblasts': '119.2', 'Syncytiotrophoblasts': '45.0', 'Extravillous trophoblasts': '24.9', 'Endothelial cells': '6.1', 'Lymphatic endothelial cells': '0.4', 'Cardiomyocytes': '0.135', 'Skeletal myocytes': '0.107', 'Smooth muscle cells': '5.8', 'Adipocytes': '2.1', 'Melanocytes': '0.335', 'Fibroblasts': '6.5', 'Peritubular cells': '0.210', 'Endometrial stromal cells': '27.7', 'Ovarian stromal cells': '0.7', 'Undifferentiated cells': '101.6', 'T-cells': '2.9', 'B-cells': '4.4', 'Plasma cells': '6.1', 'Nk-cells': '0.0', 'Granulocytes': '8.4', 'Monocytes': '0.0', 'Macrophages': '6.0', 'Hofbauer cells': '4.3', 'Kupffer cells': '1.0', 'Dendritic cells': '5.9', 'Langerhans cells': '0.304', 'Erythroid cells': '0.036', 'Adipocytes (Subcutaneous)': '-0.081', 'Adipocytes (Visceral)': '-0.209', 'Breast glandular cells (progenitors)': '0.538', 'Adipocytes (Breast)': '-0.689', 'Colon enterocytes': '0.790', 'Colon enteroendocrine cells': '0.112', 'Enteric glia cells': '-0.048', 'Mitotic cells (Colon)': '0.299', 'Mitotic cells (Heart)': '0.120', 'Podocytes': '-0.118', 'Ascending Loop of Henle cells': '0.475', 'Intercalated cells': '0.212', 'Cholangiocyte': '0.090', 'NK-cells (Liver)': '-0.005', 'Respiratory ciliated cells': '-0.012', 'Mitotic cells (Lung)': '0.071', 'NK-cells (Lung)': '-0.266', 'B-cells (Lung)': '-0.296', 'Alpha cells': '0.270', 'Beta cells': '0.152', 'Prostate glandular cells': '0.764', 'Prostate basal glandular cells': '0.540', 'Urothelial cells': '0.205', 'Keratinocyte (other)': '0.510', 'Keratinocyte (granular)': '0.055', 'Hair cortex cells': '0.080', 'Inner root sheath cells': '0.131', 'Outer root sheath cells': '0.175', 'Sebaceous gland cells': '0.156', 'Eccrine sweat gland cells': '-0.207', 'Adipocytes (Skin)': '-0.244', 'Mitotic cells (Skin)': '0.442', 'Parietal cells': '0.654', 'Chief cells': '0.649', 'Gastric mucous cells': '0.781', 'Gastric enteroendocrine cells': '0.590', 'Mitotic cells (Stomach)': '0.445', 'Parafollicular cells': '0.173', 'Thyroid glandular cells': '0.865', 'Mitotic cells (Thyroid)': '-0.081', 'Adrenal cortex cells': '0.051', 'Adrenal medulla cells': '0.087', 'Mitotic cells (Adrenal gland)': '0.072', 'Minor salivary glandular cells': '0.371', 'Minor salivary gland ductal cells': '-0.142', 'Minor salivary gland basal cells': '0.582', 'Mitotic cells (Minor salivary gland)': '0.567', 'Adipocytes (Minor salivary gland)': '0.050', 'Somatotropes': '0.121', 'Lactotropes': '0.322', 'Gonadotropes': '0.330', 'Corticotropes': '0.180', 'Thyrotropes': '0.496', 'Undifferentiated cells (Pituitary gland)': '-0.108', 'Mitotic cells (Spleen)': '-0.228', 'Platelets': '-0.050', 'Erythrocytes': '-0.158', 'Hematopoietic stem cells': '-0.211', 'B-cells (Spleen)': '0.266', 'NK-cells (Spleen)': '0.309', 'Amygdala excitatory': '1.0', 'Cerebellar inhibitory': '0.9', 'Cge interneuron': '0.7', 'Deep-layer corticothalamic and 6b': '1.5', 'Deep-layer intratelencephalic': '0.7', 'Deep-layer near-projecting': '0.7', 'Eccentric medium spiny neuron': '0.6', 'Hippocampal ca1-3': '1.9', 'Hippocampal ca4': '1.2', 'Hippocampal dentate gyrus': '1.1', 'Lamp5-lhx6 and chandelier': '0.5', 'Lower rhombic lip': '0.8', 'Mammillary body': '0.6', 'Medium spiny neuron': '0.7', 'Mge interneuron': '1.7', 'Midbrain-derived inhibitory': '0.7', 'Miscellaneous': '0.9', 'Splatter': '3.8', 'Thalamic excitatory': '0.5', 'Upper rhombic lip': '0.8', 'Upper-layer intratelencephalic': '0.6', 'Astrocyte': '4.4', 'Bergmann glia': '0.2', 'Central nervous system macrophage': '0.6', 'Choroid plexus epithelial cell': '52.1', 'Committed oligodendrocyte precursor': '41.5', 'Ependymal cell': '4.8', 'Oligodendrocyte': '53.1', 'Oligodendrocyte precursor cell': '2.4', 'Endothelial cell': '0.7', 'Pericyte': '0.3', 'Vascular associated smooth muscle cell': '0.0', 'Fibroblast': '17.4', 'Leukocyte': '1.1', 'Basophil': '0.0', 'Eosinophil': '0.0', 'Neutrophil': '0.0', 'Classical monocyte': '0.0', 'Non-classical monocyte': '0.0', 'Intermediate monocyte': '0.0', 'T-reg': '2.3', 'GdT-cell': '0.0', 'MAIT T-cell': '0.0', 'Memory CD4 T-cell': '0.0', 'Naive CD4 T-cell': '0.1', 'Memory CD8 T-cell': '0.2', 'Naive CD8 T-cell': '0.3', 'Memory B-cell': '0.0', 'Naive B-cell': '0.1', 'Plasmacytoid DC': '46.6', 'Myeloid DC': '8.5', 'NK-cell': '0.1', 'Total PBMC': '0.7', 'Vd2 gdTCR': '0.0', 'Memory CD4 T-cell Th1\\/Th17': '0.1', 'Memory CD4 T-cell Th17': '0.2', 'Memory CD4 T-cell Th2': '2.9', 'Non-Vd2 gdTCR': '0.1', 'Memory CD4 T-cell Th1': '0.3', 'Memory CD4 T-cell TFH': '0.5', 'Terminal effector memory CD4 T-cell': '0.0', 'Central memory CD8 T-cell': '4.8', 'Effector memory CD8 T-cell': '0.0', 'Terminal effector memory CD8 T-cell': '0.6', 'Non-switched memory B-cell': '0.0', 'Plasmablast': '3.3', 'Switched memory B-cell': '0.0', 'Exhausted memory B-cell': '0.7', 'Progenitor cell': '2.3', 'Memory T-reg': '1.3', 'Naive CD4 T-cell activated': '0.3', 'Naive CD8 T-cell activated': '0.6', 'Naive T-reg': '0.1'}
1O6S, 2O72, 2OMT, 2OMU, 2OMV, 2OMX, 2OMY, 2OMZ, 3FF7, 3FF8, 3L6X, 3L6Y, 4ZT1, 4ZTE, 6CXY, 6OLE, 6OLF, 6OLG, 6VEL, 7STZ, 8H62
{'Adipose Tissue': 1.2125261088039867, 'Adrenal Gland': 0.1914223992248062, 'Bladder': 39.2033519047619, 'Blood': 1.340954264800861, 'Blood Vessel': 0.3121561692883895, 'Brain': 0.8550442199091597, 'Breast': 38.54918344226579, 'Cervix Uteri': 23.539115789473684, 'Colon': 43.41292142490372, 'Esophagus': 53.97513367404844, 'Fallopian Tube': 14.900277777777776, 'Heart': 0.119140469221835, 'Kidney': 25.040449438202245, 'Liver': 26.60802654867257, 'Lung': 35.447986366782004, 'Muscle': 0.1378936151930261, 'Nerve': 17.518468982229404, 'Ovary': 3.6515122222222223, 'Pancreas': 56.89676829268293, 'Pituitary': 24.68741660777385, 'Prostate': 61.279967346938776, 'Salivary Gland': 92.01685185185184, 'Skin': 79.77571720232172, 'Small Intestine': 71.7519320855615, 'Spleen': 10.061029045643156, 'Stomach': 58.07813805013927, 'Testis': 0.8144204986149585, 'Thyroid': 135.176797856049, 'Uterus': 1.442593943661972, 'Vagina': 86.52345512820513}
CKAP2
MSTPAVPQDLQLPPSQRAQSAFKEQRRQKLKEHLLRRKTLFAYKQENEMLSSRDQRVVTSEDQVQEGTKVLKLKTKMADKENMKRPAESKNNTVVGKHCIPLKPSNELTNSTVVIDTHKPKDSNQTPHLLLTEDDPQSQHMTLSQAFHLKNNSKKKQMTTEKQKQDANMPKKPVLGSYRGQIVQSKINSFRKPLQVKDESSAATKKLSATIPKATKPQPVNTSSVTVKSNRSSNMTATTKFVSTTSQNTQLVRPPIRSHHSNTRDTVKQGISRTSANVTIRKGPHEKELLQSKTALSSVKTSSSQGIIRNKTLSRSIASEVIARPASLSNDKLMEKSEPVDQRRHTAGKAIVDSRSAQPKETSEERKARLSEWKAGKGRVLKRPPNSVVTQHEPAGQNEKPVGSFWTTMAEEDEQRLFTEKVNNTFSECLNLINEGCPKEDILVTLNDLIKNIPDAKKLVKYWICLALIEPITSPIENIIAIYEKAILAGAQPIEEMRHTIVDILTMKSQEKANLGENMEKSCASKEEVKEVSIEDTGVDVDPEKLEMESKLHRNLLFQDCEKEQDNKTKDPTHDVKTPNTETRTSCLIKYNVSTTPYLQSVKKKVQFDGTNSAFKELKFLTPVRRSRRLQEKTSKLPDMLKDHYPCVSSLEQLTELGRETDAFVCRPNAALCRVYYEADTT
Homo sapiens
null
Not found
{}
null
{'Adipose Tissue': 4.280651976744187, 'Adrenal Gland': 7.484100387596899, 'Bladder': 5.046142857142857, 'Blood': 10.339545209903122, 'Blood Vessel': 3.654278951310862, 'Brain': 5.928422823618471, 'Breast': 3.9675289760348584, 'Cervix Uteri': 4.338315789473684, 'Colon': 4.377415789473684, 'Esophagus': 6.548149134948098, 'Fallopian Tube': 3.0292222222222223, 'Heart': 1.8164202787456445, 'Kidney': 2.3842370786516853, 'Liver': 1.4220862831858407, 'Lung': 5.353738062283737, 'Muscle': 2.016712391033624, 'Nerve': 4.852846526655896, 'Ovary': 3.9144055555555552, 'Pancreas': 0.919306493902439, 'Pituitary': 7.795000000000001, 'Prostate': 4.071029795918367, 'Salivary Gland': 5.9194506172839505, 'Skin': 20.163732448866774, 'Small Intestine': 6.9891016042780745, 'Spleen': 8.95429460580913, 'Stomach': 2.773699164345404, 'Testis': 27.759362880886425, 'Thyroid': 4.374940275650842, 'Uterus': 3.97512676056338, 'Vagina': 8.247121794871795}
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null
null
null
Component of an E-cadherin/ catenin adhesion complex composed of at least E-cadherin/CDH1, beta-catenin/CTNNB1 or gamma-catenin/JUP, and potentially alpha-catenin/CTNNA1. Forms a ternary complex composed of ADAM10, CADH1 and EPHA4,
null
null
KLRG1, SPEF1, DLGAP5, AJAP1, RAPGEF2, RAB8B, PIP5K1C, PKP2, TRPV4, CTNNB1, CAV1, DDR1, TBC1D2, CTNNA1, JUP, CTNND1, PSEN1, LIMA1, CDH1, JUP, ADAM10, CADH1 , EPHA4,
null
null
null
null
Homodimer
null
79.91949
0.474025
null
null
1,063
P12830
Q8WWL7
null
degron_data
CDH1
MGPWSRSLSALLLLLQVSSWLCQEPEPCHPGFDAESYTFTVPRRHLERGRVLGRVNFEDCTGRQRTAYFSLDTRFKVGTDGVITVKRPLRFHNPQIHFLVYAWDSTYRKFSTKVTLNTVGHHHRPPPHQASVSGIQAELLTFPNSSPGLRRQKRDWVIPPISCPENEKGPFPKNLVQIKSNKDKEGKVFYSITGQGADTPPVGVFIIERETGWLKVTEPLDRERIATYTLFSHAVSSNGNAVEDPMEILITVTDQNDNKPEFTQEVFKGSVMEGALPGTSVMEVTATDADDDVNTYNAAIAYTILSQDPELPDKNMFTINRNTGVISVVTTGLDRESFPTYTLVVQAADLQGEGLSTTATAVITVTDTNDNPPIFNPTTYKGQVPENEANVVITTLKVTDADAPNTPAWEAVYTILNDDGGQFVVTTNPVNNDGILKTAKGLDFEAKQQYILHVAVTNVVPFEVSLTTSTATVTVDVLDVNEAPIFVPPEKRVEVSEDFGVGQEITSYTAQEPDTFMEQKITYRIWRDTANWLEINPDTGAISTRAELDREDFEHVKNSTYTALIIATDNGSPVATGTGTLLLILSDVNDNAPIPEPRTIFFCERNPKPQVINIIDADLPPNTSPFTAELTHGASANWTIQYNDPTQESIILKPKMALEVGDYKINLKLMDNQNKDQVTTLEVSVCDCEGAAGVCRKAQPVEAGLQIPAILGILGGILALLILILLLLLFLRRRAVVKEPLLPPEDDTRDNVYYYDEEGGGEEDQDFDLSQLHRGLDARPEVTRNDVAPTLMSVPRYLPRPANPDEIGNFIDENLKAADTDPTAPPYDSLLVFDYEGSGSEAASLSSLNSSESDKDQDYDYLNEWGNRFKKLADMYGGGEDD
Homo sapiens
Cell junction, adherens junction, Cell membrane, Endosome, Golgi apparatus, trans-Golgi network, Cytoplasm, Cell junction, desmosome
Tissue enhanced (parathyroid)
{'Ciliated cells': '119.1', 'Basal respiratory cells': '71.1', 'Club cells': '97.3', 'Ionocytes': '81.0', 'Mucus glandular cells': '155.0', 'Serous glandular cells': '67.8', 'Gastric mucus-secreting cells': '133.2', 'Proximal enterocytes': '140.9', 'Paneth cells': '125.1', 'Distal enterocytes': '307.5', 'Intestinal goblet cells': '173.5', 'Exocrine glandular cells': '-0.605', 'Basal prostatic cells': '68.3', 'Prostatic glandular cells': '186.7', 'Breast glandular cells': '0.773', 'Breast myoepithelial cells': '0.700', 'Glandular and luminal cells': '313.0', 'Secretory cells': '82.3', 'Basal keratinocytes': '102.5', 'Suprabasal keratinocytes': '162.6', 'Basal squamous epithelial cells': '51.0', 'Squamous epithelial cells': '106.9', 'Alveolar cells type 1': '0.437', 'Alveolar cells type 2': '0.706', 'Salivary duct cells': '95.9', 'Ductal cells': '0.541', 'Hepatocytes': '0.600', 'Cholangiocytes': '129.7', 'Proximal tubular cells': '0.042', 'Distal tubular cells': '0.0', 'Collecting duct cells': '143.9', 'Mesothelial cells': '0.799', 'Sertoli cells': '0.252', 'Granulosa cells': '12.9', 'Enteroendocrine cells': '92.4', 'Pancreatic endocrine cells': '78.1', 'Leydig cells': '0.264', 'Excitatory neurons': '0.7', 'Inhibitory neurons': '1.3', 'Cone photoreceptor cells': '0.0', 'Rod photoreceptor cells': '0.0', 'Bipolar cells': '0.2', 'Horizontal cells': '0.6', 'Astrocytes': '0.6', 'Oligodendrocyte precursor cells': '0.5', 'Oligodendrocytes': '29.9', 'Microglial cells': '0.9', 'Muller glia cells': '0.1', 'Schwann cells': '0.131', 'Spermatogonia': '0.392', 'Spermatocytes': '0.193', 'Early spermatids': '-0.217', 'Late spermatids': '-0.290', 'Oocytes': '16.9', 'Cytotrophoblasts': '119.2', 'Syncytiotrophoblasts': '45.0', 'Extravillous trophoblasts': '24.9', 'Endothelial cells': '6.1', 'Lymphatic endothelial cells': '0.4', 'Cardiomyocytes': '0.135', 'Skeletal myocytes': '0.107', 'Smooth muscle cells': '5.8', 'Adipocytes': '2.1', 'Melanocytes': '0.335', 'Fibroblasts': '6.5', 'Peritubular cells': '0.210', 'Endometrial stromal cells': '27.7', 'Ovarian stromal cells': '0.7', 'Undifferentiated cells': '101.6', 'T-cells': '2.9', 'B-cells': '4.4', 'Plasma cells': '6.1', 'Nk-cells': '0.0', 'Granulocytes': '8.4', 'Monocytes': '0.0', 'Macrophages': '6.0', 'Hofbauer cells': '4.3', 'Kupffer cells': '1.0', 'Dendritic cells': '5.9', 'Langerhans cells': '0.304', 'Erythroid cells': '0.036', 'Adipocytes (Subcutaneous)': '-0.081', 'Adipocytes (Visceral)': '-0.209', 'Breast glandular cells (progenitors)': '0.538', 'Adipocytes (Breast)': '-0.689', 'Colon enterocytes': '0.790', 'Colon enteroendocrine cells': '0.112', 'Enteric glia cells': '-0.048', 'Mitotic cells (Colon)': '0.299', 'Mitotic cells (Heart)': '0.120', 'Podocytes': '-0.118', 'Ascending Loop of Henle cells': '0.475', 'Intercalated cells': '0.212', 'Cholangiocyte': '0.090', 'NK-cells (Liver)': '-0.005', 'Respiratory ciliated cells': '-0.012', 'Mitotic cells (Lung)': '0.071', 'NK-cells (Lung)': '-0.266', 'B-cells (Lung)': '-0.296', 'Alpha cells': '0.270', 'Beta cells': '0.152', 'Prostate glandular cells': '0.764', 'Prostate basal glandular cells': '0.540', 'Urothelial cells': '0.205', 'Keratinocyte (other)': '0.510', 'Keratinocyte (granular)': '0.055', 'Hair cortex cells': '0.080', 'Inner root sheath cells': '0.131', 'Outer root sheath cells': '0.175', 'Sebaceous gland cells': '0.156', 'Eccrine sweat gland cells': '-0.207', 'Adipocytes (Skin)': '-0.244', 'Mitotic cells (Skin)': '0.442', 'Parietal cells': '0.654', 'Chief cells': '0.649', 'Gastric mucous cells': '0.781', 'Gastric enteroendocrine cells': '0.590', 'Mitotic cells (Stomach)': '0.445', 'Parafollicular cells': '0.173', 'Thyroid glandular cells': '0.865', 'Mitotic cells (Thyroid)': '-0.081', 'Adrenal cortex cells': '0.051', 'Adrenal medulla cells': '0.087', 'Mitotic cells (Adrenal gland)': '0.072', 'Minor salivary glandular cells': '0.371', 'Minor salivary gland ductal cells': '-0.142', 'Minor salivary gland basal cells': '0.582', 'Mitotic cells (Minor salivary gland)': '0.567', 'Adipocytes (Minor salivary gland)': '0.050', 'Somatotropes': '0.121', 'Lactotropes': '0.322', 'Gonadotropes': '0.330', 'Corticotropes': '0.180', 'Thyrotropes': '0.496', 'Undifferentiated cells (Pituitary gland)': '-0.108', 'Mitotic cells (Spleen)': '-0.228', 'Platelets': '-0.050', 'Erythrocytes': '-0.158', 'Hematopoietic stem cells': '-0.211', 'B-cells (Spleen)': '0.266', 'NK-cells (Spleen)': '0.309', 'Amygdala excitatory': '1.0', 'Cerebellar inhibitory': '0.9', 'Cge interneuron': '0.7', 'Deep-layer corticothalamic and 6b': '1.5', 'Deep-layer intratelencephalic': '0.7', 'Deep-layer near-projecting': '0.7', 'Eccentric medium spiny neuron': '0.6', 'Hippocampal ca1-3': '1.9', 'Hippocampal ca4': '1.2', 'Hippocampal dentate gyrus': '1.1', 'Lamp5-lhx6 and chandelier': '0.5', 'Lower rhombic lip': '0.8', 'Mammillary body': '0.6', 'Medium spiny neuron': '0.7', 'Mge interneuron': '1.7', 'Midbrain-derived inhibitory': '0.7', 'Miscellaneous': '0.9', 'Splatter': '3.8', 'Thalamic excitatory': '0.5', 'Upper rhombic lip': '0.8', 'Upper-layer intratelencephalic': '0.6', 'Astrocyte': '4.4', 'Bergmann glia': '0.2', 'Central nervous system macrophage': '0.6', 'Choroid plexus epithelial cell': '52.1', 'Committed oligodendrocyte precursor': '41.5', 'Ependymal cell': '4.8', 'Oligodendrocyte': '53.1', 'Oligodendrocyte precursor cell': '2.4', 'Endothelial cell': '0.7', 'Pericyte': '0.3', 'Vascular associated smooth muscle cell': '0.0', 'Fibroblast': '17.4', 'Leukocyte': '1.1', 'Basophil': '0.0', 'Eosinophil': '0.0', 'Neutrophil': '0.0', 'Classical monocyte': '0.0', 'Non-classical monocyte': '0.0', 'Intermediate monocyte': '0.0', 'T-reg': '2.3', 'GdT-cell': '0.0', 'MAIT T-cell': '0.0', 'Memory CD4 T-cell': '0.0', 'Naive CD4 T-cell': '0.1', 'Memory CD8 T-cell': '0.2', 'Naive CD8 T-cell': '0.3', 'Memory B-cell': '0.0', 'Naive B-cell': '0.1', 'Plasmacytoid DC': '46.6', 'Myeloid DC': '8.5', 'NK-cell': '0.1', 'Total PBMC': '0.7', 'Vd2 gdTCR': '0.0', 'Memory CD4 T-cell Th1\\/Th17': '0.1', 'Memory CD4 T-cell Th17': '0.2', 'Memory CD4 T-cell Th2': '2.9', 'Non-Vd2 gdTCR': '0.1', 'Memory CD4 T-cell Th1': '0.3', 'Memory CD4 T-cell TFH': '0.5', 'Terminal effector memory CD4 T-cell': '0.0', 'Central memory CD8 T-cell': '4.8', 'Effector memory CD8 T-cell': '0.0', 'Terminal effector memory CD8 T-cell': '0.6', 'Non-switched memory B-cell': '0.0', 'Plasmablast': '3.3', 'Switched memory B-cell': '0.0', 'Exhausted memory B-cell': '0.7', 'Progenitor cell': '2.3', 'Memory T-reg': '1.3', 'Naive CD4 T-cell activated': '0.3', 'Naive CD8 T-cell activated': '0.6', 'Naive T-reg': '0.1'}
1O6S, 2O72, 2OMT, 2OMU, 2OMV, 2OMX, 2OMY, 2OMZ, 3FF7, 3FF8, 3L6X, 3L6Y, 4ZT1, 4ZTE, 6CXY, 6OLE, 6OLF, 6OLG, 6VEL, 7STZ, 8H62
{'Adipose Tissue': 1.2125261088039867, 'Adrenal Gland': 0.1914223992248062, 'Bladder': 39.2033519047619, 'Blood': 1.340954264800861, 'Blood Vessel': 0.3121561692883895, 'Brain': 0.8550442199091597, 'Breast': 38.54918344226579, 'Cervix Uteri': 23.539115789473684, 'Colon': 43.41292142490372, 'Esophagus': 53.97513367404844, 'Fallopian Tube': 14.900277777777776, 'Heart': 0.119140469221835, 'Kidney': 25.040449438202245, 'Liver': 26.60802654867257, 'Lung': 35.447986366782004, 'Muscle': 0.1378936151930261, 'Nerve': 17.518468982229404, 'Ovary': 3.6515122222222223, 'Pancreas': 56.89676829268293, 'Pituitary': 24.68741660777385, 'Prostate': 61.279967346938776, 'Salivary Gland': 92.01685185185184, 'Skin': 79.77571720232172, 'Small Intestine': 71.7519320855615, 'Spleen': 10.061029045643156, 'Stomach': 58.07813805013927, 'Testis': 0.8144204986149585, 'Thyroid': 135.176797856049, 'Uterus': 1.442593943661972, 'Vagina': 86.52345512820513}
CCNB3
MLLPLPPQSSKPVPKKSQSSKIVPSHHDPSEKTGENCQTKISPSSLQESPSSLQGALKKRSAFEDLTNASQCQPVQPKKEANKEFVKVVSKKINRNTHALGLAKKNKRNLKWHKLEVTPVVASTTVVPNIMEKPLILDISTTSKTPNTEEASLFRKPLVLKEEPTIEDETLINKSLSLKKCSNHEEVSLLEKLQPLQEESDSDDAFVIEPMTFKKTHKTEEAAITKKTLSLKKKMCASQRKQSCQEESLAVQDVNMEEDSFFMESMSFKKKPKTEESIPTHKLSSLKKKCTIYGKICHFRKPPVLQTTICGAMSSIKKPTTEKETLFQELSVLQEKHTTEHEMSILKKSLALQKTNFKEDSLVKESLAFKKKPSTEEAIMMPVILKEQCMTEGKRSRLKPLVLQEITSGEKSLIMKPLSIKEKPSTEKESFSQEPSALQKKHTTQEEVSILKEPSSLLKSPTEESPFDEALAFTKKCTIEEAPPTKKPLILKRKHATQGTMSHLKKPLILQTTSGEKSLIKEPLPFKEEKVSLKKKCTTQEMMSICPELLDFQDMIGEDKNSFFMEPMSFRKNPTTEETVLTKTSLSLQEKKITQGKMSHLKKPLVLQKITSEEESFYKKLLPFKMKSTTEEKFLSQEPSALKEKHTTLQEVSLSKESLAIQEKATTEEEFSQELFSLHVKHTNKSGSLFQEALVLQEKTDAEEDSLKNLLALQEKSTMEEESLINKLLALKEELSAEAATNIQTQLSLKKKSTSHGKVFFLKKQLALNETINEEEFLNKQPLALEGYPSIAEGETLFKKLLAMQEEPSIEKEAVLKEPTIDTEAHFKEPLALQEEPSTEKEAVLKEPSVDTEAHFKETLALQEKPSIEQEALFKRHSALWEKPSTEKETIFKESLDLQEKPSIKKETLLKKPLALKMSTINEAVLFEDMIALNEKPTTGKELSFKEPLALQESPTYKEDTFLKTLLVPQVGTSPNVSSTAPESITSKSSIATMTSVGKSGTINEAFLFEDMITLNEKPTTGKELSFKEPLALQESPTCKEDTFLETFLIPQIGTSPYVFSTTPESITEKSSIATMTSVGKSRTTTESSACESASDKPVSPQAKGTPKEITPREDIDEDSSDPSFNPMYAKEIFSYMKEREEQFILTDYMNRQIEITSDMRAILVDWLVEVQVSFEMTHETLYLAVKLVDLYLMKAVCKKDKLQLLGATAFMIAAKFEEHNSPRVDDFVYICDDNYQRSEVLSMEINILNVLKCDINIPIAYHFLRRYARCIHTNMKTLTLSRYICEMTLQEYHYVQEKASKLAAASLLLALYMKKLGYWVPFLEHYSGYSISELHPLVRQLNKLLTFSSYDSLKAVYYKYSHPVFFEVAKIPALDMLKLEEILNCDCEAQGLVL
Homo sapiens
Nucleus
Group enriched (brain, epididymis, testis)
{'Ciliated cells': '0.9', 'Basal respiratory cells': '0.2', 'Club cells': '0.4', 'Ionocytes': '0.0', 'Mucus glandular cells': '0.5', 'Serous glandular cells': '0.1', 'Gastric mucus-secreting cells': '2.9', 'Proximal enterocytes': '0.0', 'Paneth cells': '0.1', 'Distal enterocytes': '0.0', 'Intestinal goblet cells': '0.4', 'Exocrine glandular cells': '-0.247', 'Basal prostatic cells': '0.2', 'Prostatic glandular cells': '0.0', 'Breast glandular cells': '0.201', 'Breast myoepithelial cells': '0.058', 'Glandular and luminal cells': '0.2', 'Secretory cells': '0.1', 'Basal keratinocytes': '0.2', 'Suprabasal keratinocytes': '0.1', 'Basal squamous epithelial cells': '0.2', 'Squamous epithelial cells': '0.4', 'Alveolar cells type 1': '0.270', 'Alveolar cells type 2': '0.293', 'Salivary duct cells': '0.2', 'Ductal cells': '0.277', 'Hepatocytes': '0.301', 'Cholangiocytes': '0.0', 'Proximal tubular cells': '0.065', 'Distal tubular cells': '0.0', 'Collecting duct cells': '0.0', 'Mesothelial cells': '-0.058', 'Sertoli cells': '0.229', 'Granulosa cells': '0.3', 'Enteroendocrine cells': '0.0', 'Pancreatic endocrine cells': '0.0', 'Leydig cells': '0.231', 'Excitatory neurons': '0.5', 'Inhibitory neurons': '0.4', 'Cone photoreceptor cells': '0.0', 'Rod photoreceptor cells': '0.7', 'Bipolar cells': '1.2', 'Horizontal cells': '0.6', 'Astrocytes': '1.5', 'Oligodendrocyte precursor cells': '0.0', 'Oligodendrocytes': '8.5', 'Microglial cells': '1.8', 'Muller glia cells': '0.3', 'Schwann cells': '0.077', 'Spermatogonia': '0.533', 'Spermatocytes': '0.778', 'Early spermatids': '-0.144', 'Late spermatids': '-0.237', 'Oocytes': '8.1', 'Cytotrophoblasts': '0.0', 'Syncytiotrophoblasts': '0.0', 'Extravillous trophoblasts': '0.0', 'Endothelial cells': '0.2', 'Lymphatic endothelial cells': '0.1', 'Cardiomyocytes': '0.526', 'Skeletal myocytes': '-0.196', 'Smooth muscle cells': '0.2', 'Adipocytes': '0.0', 'Melanocytes': '0.162', 'Fibroblasts': '0.0', 'Peritubular cells': '0.085', 'Endometrial stromal cells': '0.2', 'Ovarian stromal cells': '0.0', 'Undifferentiated cells': '0.1', 'T-cells': '0.3', 'B-cells': '0.2', 'Plasma cells': '0.2', 'Nk-cells': '2.3', 'Granulocytes': '0.0', 'Monocytes': '0.4', 'Macrophages': '0.6', 'Hofbauer cells': '0.1', 'Kupffer cells': '1.5', 'Dendritic cells': '0.0', 'Langerhans cells': '0.250', 'Erythroid cells': '0.000', 'Adipocytes (Subcutaneous)': '0.554', 'Adipocytes (Visceral)': '0.503', 'Breast glandular cells (progenitors)': '0.078', 'Adipocytes (Breast)': '0.072', 'Colon enterocytes': '0.084', 'Colon enteroendocrine cells': '0.103', 'Enteric glia cells': '-0.216', 'Mitotic cells (Colon)': '0.093', 'Mitotic cells (Heart)': '0.369', 'Podocytes': '-0.112', 'Ascending Loop of Henle cells': '0.590', 'Intercalated cells': '0.072', 'Cholangiocyte': '0.135', 'NK-cells (Liver)': '-0.139', 'Respiratory ciliated cells': '0.022', 'Mitotic cells (Lung)': '-0.010', 'NK-cells (Lung)': '0.011', 'B-cells (Lung)': '-0.202', 'Alpha cells': '0.248', 'Beta cells': '0.114', 'Prostate glandular cells': '0.230', 'Prostate basal glandular cells': '0.467', 'Urothelial cells': '0.284', 'Keratinocyte (other)': '0.301', 'Keratinocyte (granular)': '0.152', 'Hair cortex cells': '-0.150', 'Inner root sheath cells': '-0.155', 'Outer root sheath cells': '-0.105', 'Sebaceous gland cells': '0.089', 'Eccrine sweat gland cells': '-0.011', 'Adipocytes (Skin)': '-0.073', 'Mitotic cells (Skin)': '0.253', 'Parietal cells': '0.714', 'Chief cells': '0.612', 'Gastric mucous cells': '0.649', 'Gastric enteroendocrine cells': '0.526', 'Mitotic cells (Stomach)': '0.315', 'Parafollicular cells': '0.108', 'Thyroid glandular cells': '0.488', 'Mitotic cells (Thyroid)': '-0.031', 'Adrenal cortex cells': '0.631', 'Adrenal medulla cells': '0.069', 'Mitotic cells (Adrenal gland)': '0.468', 'Minor salivary glandular cells': '0.391', 'Minor salivary gland ductal cells': '0.082', 'Minor salivary gland basal cells': '0.190', 'Mitotic cells (Minor salivary gland)': '0.326', 'Adipocytes (Minor salivary gland)': '0.113', 'Somatotropes': '0.594', 'Lactotropes': '0.231', 'Gonadotropes': '0.061', 'Corticotropes': '0.159', 'Thyrotropes': '0.053', 'Undifferentiated cells (Pituitary gland)': '-0.347', 'Mitotic cells (Spleen)': '-0.069', 'Platelets': '0.181', 'Erythrocytes': '-0.174', 'Hematopoietic stem cells': '-0.001', 'B-cells (Spleen)': '0.120', 'NK-cells (Spleen)': '0.080', 'Amygdala excitatory': '1.4', 'Cerebellar inhibitory': '0.7', 'Cge interneuron': '0.7', 'Deep-layer corticothalamic and 6b': '1.6', 'Deep-layer intratelencephalic': '1.6', 'Deep-layer near-projecting': '3.1', 'Eccentric medium spiny neuron': '2.3', 'Hippocampal ca1-3': '0.8', 'Hippocampal ca4': '1.1', 'Hippocampal dentate gyrus': '0.7', 'Lamp5-lhx6 and chandelier': '0.3', 'Lower rhombic lip': '2.9', 'Mammillary body': '3.1', 'Medium spiny neuron': '0.7', 'Mge interneuron': '1.1', 'Midbrain-derived inhibitory': '5.4', 'Miscellaneous': '0.7', 'Splatter': '2.0', 'Thalamic excitatory': '3.0', 'Upper rhombic lip': '0.6', 'Upper-layer intratelencephalic': '0.9', 'Astrocyte': '3.2', 'Bergmann glia': '5.3', 'Central nervous system macrophage': '3.4', 'Choroid plexus epithelial cell': '1.2', 'Committed oligodendrocyte precursor': '5.3', 'Ependymal cell': '2.6', 'Oligodendrocyte': '17.7', 'Oligodendrocyte precursor cell': '2.5', 'Endothelial cell': '0.7', 'Pericyte': '0.5', 'Vascular associated smooth muscle cell': '0.0', 'Fibroblast': '0.6', 'Leukocyte': '1.6', 'Basophil': '0.0', 'Eosinophil': '0.0', 'Neutrophil': '0.0', 'Classical monocyte': '0.1', 'Non-classical monocyte': '0.6', 'Intermediate monocyte': '0.8', 'T-reg': '0.1', 'GdT-cell': '0.3', 'MAIT T-cell': '0.0', 'Memory CD4 T-cell': '0.0', 'Naive CD4 T-cell': '0.4', 'Memory CD8 T-cell': '0.0', 'Naive CD8 T-cell': '0.4', 'Memory B-cell': '0.0', 'Naive B-cell': '1.0', 'Plasmacytoid DC': '0.1', 'Myeloid DC': '0.7', 'NK-cell': '4.0', 'Total PBMC': '0.4', 'Vd2 gdTCR': '0.3', 'Memory CD4 T-cell Th1\\/Th17': '0.2', 'Memory CD4 T-cell Th17': '0.1', 'Memory CD4 T-cell Th2': '0.2', 'Non-Vd2 gdTCR': '1.7', 'Memory CD4 T-cell Th1': '0.2', 'Memory CD4 T-cell TFH': '0.2', 'Terminal effector memory CD4 T-cell': '0.0', 'Central memory CD8 T-cell': '0.2', 'Effector memory CD8 T-cell': '0.2', 'Terminal effector memory CD8 T-cell': '0.9', 'Non-switched memory B-cell': '0.0', 'Plasmablast': '0.0', 'Switched memory B-cell': '0.1', 'Exhausted memory B-cell': '0.0', 'Progenitor cell': '0.0', 'Memory T-reg': '0.0', 'Naive CD4 T-cell activated': '0.1', 'Naive CD8 T-cell activated': '0.1', 'Naive T-reg': '0.3'}
null
{'Adipose Tissue': 0.282478803986711, 'Adrenal Gland': 0.3962261240310077, 'Bladder': 0.2156395238095238, 'Blood': 0.0980808622174381, 'Blood Vessel': 0.1151695348314606, 'Brain': 0.4247745836487509, 'Breast': 0.3126401742919389, 'Cervix Uteri': 0.1514942105263158, 'Colon': 0.147873568677792, 'Esophagus': 0.1322234712802768, 'Fallopian Tube': 0.3328233333333333, 'Heart': 0.0650059303135888, 'Kidney': 0.208785393258427, 'Liver': 0.1976215486725663, 'Lung': 0.6179865224913494, 'Muscle': 0.381289701120797, 'Nerve': 0.495035928917609, 'Ovary': 0.1903964444444444, 'Pancreas': 0.2248087804878048, 'Pituitary': 0.9278867137809188, 'Prostate': 0.1871483673469388, 'Salivary Gland': 0.192336037037037, 'Skin': 0.3864328966279712, 'Small Intestine': 0.2327844385026738, 'Spleen': 0.3772534439834025, 'Stomach': 0.3775572980501392, 'Testis': 11.653783933518003, 'Thyroid': 0.4285230321592649, 'Uterus': 0.1282038028169014, 'Vagina': 0.1875314102564102}
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null
Component of an E-cadherin/ catenin adhesion complex composed of at least E-cadherin/CDH1, beta-catenin/CTNNB1 or gamma-catenin/JUP, and potentially alpha-catenin/CTNNA1. Forms a ternary complex composed of ADAM10, CADH1 and EPHA4,
null
null
KLRG1, SPEF1, DLGAP5, AJAP1, RAPGEF2, RAB8B, PIP5K1C, PKP2, TRPV4, CTNNB1, CAV1, DDR1, TBC1D2, CTNNA1, JUP, CTNND1, PSEN1, LIMA1, CDH1, JUP, ADAM10, CADH1 , EPHA4,
null
null
null
null
Homodimer
null
79.91949
0.474025
41.688989
0.802093
235
P12830
Q969U6
null
degron_data
CDH1
MGPWSRSLSALLLLLQVSSWLCQEPEPCHPGFDAESYTFTVPRRHLERGRVLGRVNFEDCTGRQRTAYFSLDTRFKVGTDGVITVKRPLRFHNPQIHFLVYAWDSTYRKFSTKVTLNTVGHHHRPPPHQASVSGIQAELLTFPNSSPGLRRQKRDWVIPPISCPENEKGPFPKNLVQIKSNKDKEGKVFYSITGQGADTPPVGVFIIERETGWLKVTEPLDRERIATYTLFSHAVSSNGNAVEDPMEILITVTDQNDNKPEFTQEVFKGSVMEGALPGTSVMEVTATDADDDVNTYNAAIAYTILSQDPELPDKNMFTINRNTGVISVVTTGLDRESFPTYTLVVQAADLQGEGLSTTATAVITVTDTNDNPPIFNPTTYKGQVPENEANVVITTLKVTDADAPNTPAWEAVYTILNDDGGQFVVTTNPVNNDGILKTAKGLDFEAKQQYILHVAVTNVVPFEVSLTTSTATVTVDVLDVNEAPIFVPPEKRVEVSEDFGVGQEITSYTAQEPDTFMEQKITYRIWRDTANWLEINPDTGAISTRAELDREDFEHVKNSTYTALIIATDNGSPVATGTGTLLLILSDVNDNAPIPEPRTIFFCERNPKPQVINIIDADLPPNTSPFTAELTHGASANWTIQYNDPTQESIILKPKMALEVGDYKINLKLMDNQNKDQVTTLEVSVCDCEGAAGVCRKAQPVEAGLQIPAILGILGGILALLILILLLLLFLRRRAVVKEPLLPPEDDTRDNVYYYDEEGGGEEDQDFDLSQLHRGLDARPEVTRNDVAPTLMSVPRYLPRPANPDEIGNFIDENLKAADTDPTAPPYDSLLVFDYEGSGSEAASLSSLNSSESDKDQDYDYLNEWGNRFKKLADMYGGGEDD
Homo sapiens
Cell junction, adherens junction, Cell membrane, Endosome, Golgi apparatus, trans-Golgi network, Cytoplasm, Cell junction, desmosome
Tissue enhanced (parathyroid)
{'Ciliated cells': '119.1', 'Basal respiratory cells': '71.1', 'Club cells': '97.3', 'Ionocytes': '81.0', 'Mucus glandular cells': '155.0', 'Serous glandular cells': '67.8', 'Gastric mucus-secreting cells': '133.2', 'Proximal enterocytes': '140.9', 'Paneth cells': '125.1', 'Distal enterocytes': '307.5', 'Intestinal goblet cells': '173.5', 'Exocrine glandular cells': '-0.605', 'Basal prostatic cells': '68.3', 'Prostatic glandular cells': '186.7', 'Breast glandular cells': '0.773', 'Breast myoepithelial cells': '0.700', 'Glandular and luminal cells': '313.0', 'Secretory cells': '82.3', 'Basal keratinocytes': '102.5', 'Suprabasal keratinocytes': '162.6', 'Basal squamous epithelial cells': '51.0', 'Squamous epithelial cells': '106.9', 'Alveolar cells type 1': '0.437', 'Alveolar cells type 2': '0.706', 'Salivary duct cells': '95.9', 'Ductal cells': '0.541', 'Hepatocytes': '0.600', 'Cholangiocytes': '129.7', 'Proximal tubular cells': '0.042', 'Distal tubular cells': '0.0', 'Collecting duct cells': '143.9', 'Mesothelial cells': '0.799', 'Sertoli cells': '0.252', 'Granulosa cells': '12.9', 'Enteroendocrine cells': '92.4', 'Pancreatic endocrine cells': '78.1', 'Leydig cells': '0.264', 'Excitatory neurons': '0.7', 'Inhibitory neurons': '1.3', 'Cone photoreceptor cells': '0.0', 'Rod photoreceptor cells': '0.0', 'Bipolar cells': '0.2', 'Horizontal cells': '0.6', 'Astrocytes': '0.6', 'Oligodendrocyte precursor cells': '0.5', 'Oligodendrocytes': '29.9', 'Microglial cells': '0.9', 'Muller glia cells': '0.1', 'Schwann cells': '0.131', 'Spermatogonia': '0.392', 'Spermatocytes': '0.193', 'Early spermatids': '-0.217', 'Late spermatids': '-0.290', 'Oocytes': '16.9', 'Cytotrophoblasts': '119.2', 'Syncytiotrophoblasts': '45.0', 'Extravillous trophoblasts': '24.9', 'Endothelial cells': '6.1', 'Lymphatic endothelial cells': '0.4', 'Cardiomyocytes': '0.135', 'Skeletal myocytes': '0.107', 'Smooth muscle cells': '5.8', 'Adipocytes': '2.1', 'Melanocytes': '0.335', 'Fibroblasts': '6.5', 'Peritubular cells': '0.210', 'Endometrial stromal cells': '27.7', 'Ovarian stromal cells': '0.7', 'Undifferentiated cells': '101.6', 'T-cells': '2.9', 'B-cells': '4.4', 'Plasma cells': '6.1', 'Nk-cells': '0.0', 'Granulocytes': '8.4', 'Monocytes': '0.0', 'Macrophages': '6.0', 'Hofbauer cells': '4.3', 'Kupffer cells': '1.0', 'Dendritic cells': '5.9', 'Langerhans cells': '0.304', 'Erythroid cells': '0.036', 'Adipocytes (Subcutaneous)': '-0.081', 'Adipocytes (Visceral)': '-0.209', 'Breast glandular cells (progenitors)': '0.538', 'Adipocytes (Breast)': '-0.689', 'Colon enterocytes': '0.790', 'Colon enteroendocrine cells': '0.112', 'Enteric glia cells': '-0.048', 'Mitotic cells (Colon)': '0.299', 'Mitotic cells (Heart)': '0.120', 'Podocytes': '-0.118', 'Ascending Loop of Henle cells': '0.475', 'Intercalated cells': '0.212', 'Cholangiocyte': '0.090', 'NK-cells (Liver)': '-0.005', 'Respiratory ciliated cells': '-0.012', 'Mitotic cells (Lung)': '0.071', 'NK-cells (Lung)': '-0.266', 'B-cells (Lung)': '-0.296', 'Alpha cells': '0.270', 'Beta cells': '0.152', 'Prostate glandular cells': '0.764', 'Prostate basal glandular cells': '0.540', 'Urothelial cells': '0.205', 'Keratinocyte (other)': '0.510', 'Keratinocyte (granular)': '0.055', 'Hair cortex cells': '0.080', 'Inner root sheath cells': '0.131', 'Outer root sheath cells': '0.175', 'Sebaceous gland cells': '0.156', 'Eccrine sweat gland cells': '-0.207', 'Adipocytes (Skin)': '-0.244', 'Mitotic cells (Skin)': '0.442', 'Parietal cells': '0.654', 'Chief cells': '0.649', 'Gastric mucous cells': '0.781', 'Gastric enteroendocrine cells': '0.590', 'Mitotic cells (Stomach)': '0.445', 'Parafollicular cells': '0.173', 'Thyroid glandular cells': '0.865', 'Mitotic cells (Thyroid)': '-0.081', 'Adrenal cortex cells': '0.051', 'Adrenal medulla cells': '0.087', 'Mitotic cells (Adrenal gland)': '0.072', 'Minor salivary glandular cells': '0.371', 'Minor salivary gland ductal cells': '-0.142', 'Minor salivary gland basal cells': '0.582', 'Mitotic cells (Minor salivary gland)': '0.567', 'Adipocytes (Minor salivary gland)': '0.050', 'Somatotropes': '0.121', 'Lactotropes': '0.322', 'Gonadotropes': '0.330', 'Corticotropes': '0.180', 'Thyrotropes': '0.496', 'Undifferentiated cells (Pituitary gland)': '-0.108', 'Mitotic cells (Spleen)': '-0.228', 'Platelets': '-0.050', 'Erythrocytes': '-0.158', 'Hematopoietic stem cells': '-0.211', 'B-cells (Spleen)': '0.266', 'NK-cells (Spleen)': '0.309', 'Amygdala excitatory': '1.0', 'Cerebellar inhibitory': '0.9', 'Cge interneuron': '0.7', 'Deep-layer corticothalamic and 6b': '1.5', 'Deep-layer intratelencephalic': '0.7', 'Deep-layer near-projecting': '0.7', 'Eccentric medium spiny neuron': '0.6', 'Hippocampal ca1-3': '1.9', 'Hippocampal ca4': '1.2', 'Hippocampal dentate gyrus': '1.1', 'Lamp5-lhx6 and chandelier': '0.5', 'Lower rhombic lip': '0.8', 'Mammillary body': '0.6', 'Medium spiny neuron': '0.7', 'Mge interneuron': '1.7', 'Midbrain-derived inhibitory': '0.7', 'Miscellaneous': '0.9', 'Splatter': '3.8', 'Thalamic excitatory': '0.5', 'Upper rhombic lip': '0.8', 'Upper-layer intratelencephalic': '0.6', 'Astrocyte': '4.4', 'Bergmann glia': '0.2', 'Central nervous system macrophage': '0.6', 'Choroid plexus epithelial cell': '52.1', 'Committed oligodendrocyte precursor': '41.5', 'Ependymal cell': '4.8', 'Oligodendrocyte': '53.1', 'Oligodendrocyte precursor cell': '2.4', 'Endothelial cell': '0.7', 'Pericyte': '0.3', 'Vascular associated smooth muscle cell': '0.0', 'Fibroblast': '17.4', 'Leukocyte': '1.1', 'Basophil': '0.0', 'Eosinophil': '0.0', 'Neutrophil': '0.0', 'Classical monocyte': '0.0', 'Non-classical monocyte': '0.0', 'Intermediate monocyte': '0.0', 'T-reg': '2.3', 'GdT-cell': '0.0', 'MAIT T-cell': '0.0', 'Memory CD4 T-cell': '0.0', 'Naive CD4 T-cell': '0.1', 'Memory CD8 T-cell': '0.2', 'Naive CD8 T-cell': '0.3', 'Memory B-cell': '0.0', 'Naive B-cell': '0.1', 'Plasmacytoid DC': '46.6', 'Myeloid DC': '8.5', 'NK-cell': '0.1', 'Total PBMC': '0.7', 'Vd2 gdTCR': '0.0', 'Memory CD4 T-cell Th1\\/Th17': '0.1', 'Memory CD4 T-cell Th17': '0.2', 'Memory CD4 T-cell Th2': '2.9', 'Non-Vd2 gdTCR': '0.1', 'Memory CD4 T-cell Th1': '0.3', 'Memory CD4 T-cell TFH': '0.5', 'Terminal effector memory CD4 T-cell': '0.0', 'Central memory CD8 T-cell': '4.8', 'Effector memory CD8 T-cell': '0.0', 'Terminal effector memory CD8 T-cell': '0.6', 'Non-switched memory B-cell': '0.0', 'Plasmablast': '3.3', 'Switched memory B-cell': '0.0', 'Exhausted memory B-cell': '0.7', 'Progenitor cell': '2.3', 'Memory T-reg': '1.3', 'Naive CD4 T-cell activated': '0.3', 'Naive CD8 T-cell activated': '0.6', 'Naive T-reg': '0.1'}
1O6S, 2O72, 2OMT, 2OMU, 2OMV, 2OMX, 2OMY, 2OMZ, 3FF7, 3FF8, 3L6X, 3L6Y, 4ZT1, 4ZTE, 6CXY, 6OLE, 6OLF, 6OLG, 6VEL, 7STZ, 8H62
{'Adipose Tissue': 1.2125261088039867, 'Adrenal Gland': 0.1914223992248062, 'Bladder': 39.2033519047619, 'Blood': 1.340954264800861, 'Blood Vessel': 0.3121561692883895, 'Brain': 0.8550442199091597, 'Breast': 38.54918344226579, 'Cervix Uteri': 23.539115789473684, 'Colon': 43.41292142490372, 'Esophagus': 53.97513367404844, 'Fallopian Tube': 14.900277777777776, 'Heart': 0.119140469221835, 'Kidney': 25.040449438202245, 'Liver': 26.60802654867257, 'Lung': 35.447986366782004, 'Muscle': 0.1378936151930261, 'Nerve': 17.518468982229404, 'Ovary': 3.6515122222222223, 'Pancreas': 56.89676829268293, 'Pituitary': 24.68741660777385, 'Prostate': 61.279967346938776, 'Salivary Gland': 92.01685185185184, 'Skin': 79.77571720232172, 'Small Intestine': 71.7519320855615, 'Spleen': 10.061029045643156, 'Stomach': 58.07813805013927, 'Testis': 0.8144204986149585, 'Thyroid': 135.176797856049, 'Uterus': 1.442593943661972, 'Vagina': 86.52345512820513}
FBXW5
MDEGGTPLLPDSLVYQIFLSLGPADVLAAGLVCRQWQAVSRDEFLWREQFYRYYQVARDVPRHPAAMSWYEEFQRLYDTVPCVEVQTLREHTDQVLHLSFSHSGYQFASCSKDCTVKIWSNDLTISLLHSADMRPYNWSYTQFSQFNKDDSLLLASGVFLGPHNSSSGEIAVISLDSFALLSRVRNKPYDVFGCWLTETSLISGNLHRIGDITSCSVLWLNNAFQDVESENVNVVKRLFKIQNLNASTVRTVMVADCSRFDSPDLLLEAGDPATSPCRIFDLGSDNEEVVAGPAPAHAKEGLRHFLDRVLEGRAQPQLSERMLETKVAELLAQGHTKPPERSATGAKSKYLIFTTGCLTYSPHQIGIKQILPHQMTTAGPVLGEGRGSDAFFDALDHVIDIHGHIIGMGLSPDNRYLYVNSRAWPNGAVVADPMQPPPIAEEIDLLVFDLKTMREVRRALRAHRAYTPNDECFFIFLDVSRDFVASGAEDRHGYIWDRHYNICLARLRHEDVVNSVVFSPQEQELLLTASDDATIKAWRSPRTMRVLQAPRPRPRTFFSWLASQRR
Homo sapiens
Cytoplasm
Tissue enhanced (testis)
{'Ciliated cells': '44.0', 'Basal respiratory cells': '123.6', 'Club cells': '78.2', 'Ionocytes': '93.1', 'Mucus glandular cells': '87.3', 'Serous glandular cells': '126.5', 'Gastric mucus-secreting cells': '86.7', 'Proximal enterocytes': '428.3', 'Paneth cells': '161.9', 'Distal enterocytes': '300.2', 'Intestinal goblet cells': '119.7', 'Exocrine glandular cells': '-0.709', 'Basal prostatic cells': '30.1', 'Prostatic glandular cells': '48.0', 'Breast glandular cells': '-0.282', 'Breast myoepithelial cells': '-0.420', 'Glandular and luminal cells': '41.0', 'Secretory cells': '43.9', 'Basal keratinocytes': '50.5', 'Suprabasal keratinocytes': '96.8', 'Basal squamous epithelial cells': '28.8', 'Squamous epithelial cells': '50.4', 'Alveolar cells type 1': '-0.116', 'Alveolar cells type 2': '-0.146', 'Salivary duct cells': '55.7', 'Ductal cells': '0.482', 'Hepatocytes': '0.041', 'Cholangiocytes': '49.6', 'Proximal tubular cells': '0.224', 'Distal tubular cells': '61.5', 'Collecting duct cells': '23.3', 'Mesothelial cells': '-0.052', 'Sertoli cells': '-0.545', 'Granulosa cells': '31.7', 'Enteroendocrine cells': '78.9', 'Pancreatic endocrine cells': '83.2', 'Leydig cells': '-0.618', 'Excitatory neurons': '15.4', 'Inhibitory neurons': '14.7', 'Cone photoreceptor cells': '23.8', 'Rod photoreceptor cells': '30.7', 'Bipolar cells': '26.0', 'Horizontal cells': '49.1', 'Astrocytes': '12.4', 'Oligodendrocyte precursor cells': '10.4', 'Oligodendrocytes': '15.9', 'Microglial cells': '8.1', 'Muller glia cells': '53.7', 'Schwann cells': '-0.051', 'Spermatogonia': '-0.326', 'Spermatocytes': '0.015', 'Early spermatids': '0.655', 'Late spermatids': '0.755', 'Oocytes': '6.6', 'Cytotrophoblasts': '69.6', 'Syncytiotrophoblasts': '118.5', 'Extravillous trophoblasts': '145.8', 'Endothelial cells': '51.2', 'Lymphatic endothelial cells': '36.8', 'Cardiomyocytes': '0.636', 'Skeletal myocytes': '-0.181', 'Smooth muscle cells': '65.1', 'Adipocytes': '60.0', 'Melanocytes': '-0.067', 'Fibroblasts': '46.0', 'Peritubular cells': '-0.469', 'Endometrial stromal cells': '28.0', 'Ovarian stromal cells': '32.2', 'Undifferentiated cells': '75.3', 'T-cells': '60.1', 'B-cells': '35.8', 'Plasma cells': '64.2', 'Nk-cells': '78.3', 'Granulocytes': '39.8', 'Monocytes': '67.9', 'Macrophages': '65.5', 'Hofbauer cells': '86.3', 'Kupffer cells': '52.2', 'Dendritic cells': '107.0', 'Langerhans cells': '0.289', 'Erythroid cells': '0.022', 'Adipocytes (Subcutaneous)': '0.367', 'Adipocytes (Visceral)': '0.428', 'Breast glandular cells (progenitors)': '-0.215', 'Adipocytes (Breast)': '0.544', 'Colon enterocytes': '-0.227', 'Colon enteroendocrine cells': '0.049', 'Enteric glia cells': '0.280', 'Mitotic cells (Colon)': '-0.186', 'Mitotic cells (Heart)': '0.470', 'Podocytes': '-0.140', 'Ascending Loop of Henle cells': '0.434', 'Intercalated cells': '-0.119', 'Cholangiocyte': '0.254', 'NK-cells (Liver)': '-0.268', 'Respiratory ciliated cells': '0.010', 'Mitotic cells (Lung)': '0.133', 'NK-cells (Lung)': '-0.082', 'B-cells (Lung)': '-0.110', 'Alpha cells': '0.363', 'Beta cells': '0.195', 'Prostate glandular cells': '-0.030', 'Prostate basal glandular cells': '0.018', 'Urothelial cells': '0.051', 'Keratinocyte (other)': '0.115', 'Keratinocyte (granular)': '0.151', 'Hair cortex cells': '-0.185', 'Inner root sheath cells': '-0.227', 'Outer root sheath cells': '-0.103', 'Sebaceous gland cells': '0.016', 'Eccrine sweat gland cells': '-0.264', 'Adipocytes (Skin)': '-0.067', 'Mitotic cells (Skin)': '-0.030', 'Parietal cells': '-0.701', 'Chief cells': '-0.510', 'Gastric mucous cells': '-0.377', 'Gastric enteroendocrine cells': '-0.411', 'Mitotic cells (Stomach)': '0.041', 'Parafollicular cells': '0.002', 'Thyroid glandular cells': '0.097', 'Mitotic cells (Thyroid)': '0.017', 'Adrenal cortex cells': '0.552', 'Adrenal medulla cells': '-0.003', 'Mitotic cells (Adrenal gland)': '-0.180', 'Minor salivary glandular cells': '0.369', 'Minor salivary gland ductal cells': '-0.214', 'Minor salivary gland basal cells': '0.212', 'Mitotic cells (Minor salivary gland)': '0.341', 'Adipocytes (Minor salivary gland)': '0.102', 'Somatotropes': '0.250', 'Lactotropes': '0.141', 'Gonadotropes': '0.038', 'Corticotropes': '-0.007', 'Thyrotropes': '0.021', 'Undifferentiated cells (Pituitary gland)': '-0.125', 'Mitotic cells (Spleen)': '-0.398', 'Platelets': '-0.155', 'Erythrocytes': '-0.061', 'Hematopoietic stem cells': '-0.302', 'B-cells (Spleen)': '0.296', 'NK-cells (Spleen)': '0.292', 'Amygdala excitatory': '18.1', 'Cerebellar inhibitory': '18.6', 'Cge interneuron': '20.6', 'Deep-layer corticothalamic and 6b': '23.5', 'Deep-layer intratelencephalic': '21.1', 'Deep-layer near-projecting': '22.0', 'Eccentric medium spiny neuron': '18.1', 'Hippocampal ca1-3': '20.5', 'Hippocampal ca4': '27.8', 'Hippocampal dentate gyrus': '15.7', 'Lamp5-lhx6 and chandelier': '20.7', 'Lower rhombic lip': '20.1', 'Mammillary body': '16.4', 'Medium spiny neuron': '16.1', 'Mge interneuron': '23.3', 'Midbrain-derived inhibitory': '16.6', 'Miscellaneous': '21.8', 'Splatter': '16.9', 'Thalamic excitatory': '25.3', 'Upper rhombic lip': '21.3', 'Upper-layer intratelencephalic': '25.1', 'Astrocyte': '31.2', 'Bergmann glia': '31.4', 'Central nervous system macrophage': '23.0', 'Choroid plexus epithelial cell': '16.6', 'Committed oligodendrocyte precursor': '22.5', 'Ependymal cell': '17.4', 'Oligodendrocyte': '23.6', 'Oligodendrocyte precursor cell': '19.2', 'Endothelial cell': '31.2', 'Pericyte': '40.1', 'Vascular associated smooth muscle cell': '44.8', 'Fibroblast': '22.2', 'Leukocyte': '45.0', 'Basophil': '46.9', 'Eosinophil': '88.1', 'Neutrophil': '54.3', 'Classical monocyte': '37.2', 'Non-classical monocyte': '32.5', 'Intermediate monocyte': '86.2', 'T-reg': '86.9', 'GdT-cell': '97.9', 'MAIT T-cell': '125.0', 'Memory CD4 T-cell': '74.1', 'Naive CD4 T-cell': '20.6', 'Memory CD8 T-cell': '83.3', 'Naive CD8 T-cell': '33.5', 'Memory B-cell': '39.3', 'Naive B-cell': '13.2', 'Plasmacytoid DC': '160.1', 'Myeloid DC': '99.2', 'NK-cell': '75.4', 'Total PBMC': '95.7', 'Vd2 gdTCR': '124.7', 'Memory CD4 T-cell Th1\\/Th17': '40.4', 'Memory CD4 T-cell Th17': '61.2', 'Memory CD4 T-cell Th2': '58.0', 'Non-Vd2 gdTCR': '151.6', 'Memory CD4 T-cell Th1': '76.8', 'Memory CD4 T-cell TFH': '90.4', 'Terminal effector memory CD4 T-cell': '155.1', 'Central memory CD8 T-cell': '99.6', 'Effector memory CD8 T-cell': '161.9', 'Terminal effector memory CD8 T-cell': '147.7', 'Non-switched memory B-cell': '57.1', 'Plasmablast': '140.2', 'Switched memory B-cell': '72.8', 'Exhausted memory B-cell': '70.0', 'Progenitor cell': '46.4', 'Memory T-reg': '109.3', 'Naive CD4 T-cell activated': '18.7', 'Naive CD8 T-cell activated': '21.2', 'Naive T-reg': '44.8'}
null
{'Adipose Tissue': 102.0627657807309, 'Adrenal Gland': 94.85852713178296, 'Bladder': 123.66571428571427, 'Blood': 84.69052960172228, 'Blood Vessel': 212.15970037453184, 'Brain': 66.81620552611658, 'Breast': 96.05350762527232, 'Cervix Uteri': 104.59052631578948, 'Colon': 125.90858793324774, 'Esophagus': 140.26397923875433, 'Fallopian Tube': 97.74333333333333, 'Heart': 82.29702671312428, 'Kidney': 70.42426966292135, 'Liver': 110.22973451327437, 'Lung': 98.97235294117648, 'Muscle': 157.70546699875467, 'Nerve': 102.81596122778676, 'Ovary': 81.29227777777778, 'Pancreas': 54.840152439024386, 'Pituitary': 108.0804593639576, 'Prostate': 147.33122448979591, 'Salivary Gland': 94.05975308641976, 'Skin': 84.56350469872858, 'Small Intestine': 115.30160427807488, 'Spleen': 134.7031950207469, 'Stomach': 94.5409470752089, 'Testis': 559.4195290858726, 'Thyroid': 125.43301684532923, 'Uterus': 111.94654929577464, 'Vagina': 100.93025641025642}
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[0.99, 0.84, 0.99, 0.8, 0.7, 0.85, 0.59, 0.92, 0.39, 0.56, 0.51, 0.63, 0.5, 0.02, 0.24, 0.65, 0.46, 0.02, 0.26, 0.77, 0.29, 0.41, 0.14, 0.71, 0.53, 0.0, 0.3, 0.51, 0.17, 0.04, 0.8, 0.68, 0.42, 0.85, 0.23, 0.3, 0.5, 0.61, 0.08, 0.02, 0.47, 0.33, 0.37, 0.63, 0.0, 0.0, 0.4, 0.31, 0.02, 0.0, 0.07, 0.5, 0.57, 0.14, 0.81, 0.08, 0.54, 0.56, 0.85, 0.15, 0.51, 0.27, 0.05, 0.72, 0.57, 0.14, 0.78, 0.2, 0.11, 0.21, 0.5, 0.02, 0.06, 0.39, 0.17, 0.05, 0.59, 0.06, 0.11, 0.05, 0.0, 0.44, 0.38, 0.46, 0.34, 0.24, 0.3, 0.08, 0.71, 0.56, 0.06, 0.78, 0.45, 0.26, 0.0, 0.14, 0.07, 0.04, 0.1, 0.1, 0.02, 0.45, 0.3, 0.06, 0.71, 0.28, 0.0, 0.0, 0.0, 0.0, 0.0, 0.37, 0.07, 0.09, 0.1, 0.02, 0.08, 0.01, 0.01, 0.12, 0.1, 0.58, 0.61, 0.72, 0.08, 0.46, 0.39, 0.44, 0.27, 0.47, 0.14, 0.42, 0.02, 0.55, 0.79, 0.37, 0.61, 0.04, 0.37, 0.25, 0.0, 0.07, 0.14, 0.01, 0.33, 0.03, 0.0, 0.65, 0.57, 0.18, 0.3, 0.03, 0.0, 0.0, 0.0, 0.01, 0.01, 0.06, 0.25, 0.71, 0.74, 0.68, 0.97, 0.85, 0.27, 0.28, 0.26, 0.03, 0.08, 0.0, 0.0, 0.01, 0.03, 0.12, 0.08, 0.83, 0.68, 0.28, 0.39, 0.33, 0.35, 0.04, 0.4, 0.06, 0.84, 0.01, 0.4, 0.06, 0.2, 0.02, 0.02, 0.03, 0.0, 0.03, 0.09, 0.04, 0.32, 0.4, 0.43, 0.1, 0.0, 0.0, 0.03, 0.03, 0.36, 0.24, 0.42, 0.83, 0.55, 0.35, 0.77, 0.05, 0.08, 0.07, 0.03, 0.05, 0.05, 0.01, 0.32, 0.0, 0.04, 0.3, 0.0, 0.47, 0.38, 0.71, 0.74, 0.97, 0.17, 0.65, 0.99, 0.73, 0.38, 0.38, 0.44, 0.07, 0.18, 0.03, 0.03, 0.12, 0.08, 0.23, 0.03, 0.21, 0.12, 0.28, 0.02, 0.08, 0.01, 0.17, 0.14, 0.04, 0.18, 0.2, 0.0, 0.34, 0.06, 0.51, 0.62, 0.12, 0.79, 0.62, 0.29, 0.47, 0.03, 0.67, 0.11, 0.57, 0.8, 0.51, 0.73, 0.79, 0.84, 0.84, 0.7, 0.89, 0.77, 0.83, 0.88, 0.83, 0.84, 0.92, 0.77, 0.83, 0.91, 0.92, 0.88, 0.92, 0.9, 0.85, 0.91, 0.82, 0.81, 0.81, 0.76, 0.68, 0.54, 0.21, 0.59, 0.58, 0.35, 0.18, 0.7, 0.61, 0.18, 0.43, 0.4, 0.46, 0.31, 0.82, 0.59, 0.56, 0.68, 0.31, 0.88, 0.84, 0.93, 0.43, 0.49, 0.76, 0.48, 0.56, 0.3, 0.21, 0.08, 0.39, 0.24, 0.08, 0.35, 0.13, 0.35, 0.22, 0.67, 0.38, 0.25, 0.35, 0.43, 0.89, 0.44, 0.37, 0.93, 0.36, 0.84, 0.98, 0.97, 0.43, 0.73, 0.16, 0.2, 0.18, 0.0, 0.0, 0.0, 0.01, 0.12, 0.0, 0.39, 0.43, 0.0, 0.26, 0.02, 0.12, 0.0, 0.13, 0.0, 0.0, 0.0, 0.08, 0.13, 0.01, 0.1, 0.59, 0.62, 0.1, 0.21, 0.41, 0.25, 0.6, 0.81, 0.71, 0.6, 0.23, 0.41, 0.78, 0.93, 0.31, 0.6, 0.89, 0.49, 0.39, 0.5, 0.09, 0.13, 0.2, 0.25, 0.29, 0.52, 0.54, 0.09, 0.62, 0.07, 0.42, 0.0, 0.08, 0.05, 0.02, 0.12, 0.12, 0.1, 0.19, 0.01, 0.49, 0.03, 0.18, 0.08, 0.01, 0.0, 0.01, 0.0, 0.0, 0.02, 0.03, 0.29, 0.08, 0.5, 0.92, 0.82, 0.29, 0.82, 0.2, 0.84, 0.31, 0.18, 0.43, 0.71, 0.18, 0.1, 0.62, 0.18, 0.35, 0.53, 0.42, 0.0, 0.1, 0.0, 0.13, 0.07, 0.05, 0.1, 0.02, 0.5, 0.53, 0.18, 0.72, 0.48, 0.06, 0.23, 0.93, 0.29, 0.05, 0.6, 0.35, 0.01, 0.44, 0.0, 0.47, 0.22, 0.51, 0.25, 0.73, 0.59, 0.64, 0.12, 0.24, 0.01, 0.14, 0.07, 0.22, 0.07, 0.09, 0.48, 0.13, 0.0, 0.01, 0.01, 0.0, 0.0, 0.0, 0.16, 0.16, 0.53, 0.17, 0.01, 0.06, 0.0, 0.02, 0.0, 0.0, 0.09, 0.06, 0.26, 0.14, 0.46, 0.25, 0.11, 0.54, 0.01, 0.61, 0.02, 0.59, 0.41, 0.17, 0.0, 0.08, 0.01, 0.03, 0.08, 0.04, 0.05, 0.56, 0.7, 0.48, 0.22, 0.17, 0.01, 0.01, 0.0, 0.01, 0.0, 0.0, 0.2, 0.27, 0.16, 0.05, 0.01, 0.14, 0.0, 0.04, 0.09, 0.0, 0.27, 0.5, 0.22, 0.24, 0.61, 0.67, 0.47, 0.73, 0.53, 0.89, 0.9, 0.88, 0.92, 0.86, 0.82, 0.78, 0.77, 0.78, 0.65, 0.8, 0.69, 0.67, 0.71, 0.79, 0.9, 0.96]
null
Component of an E-cadherin/ catenin adhesion complex composed of at least E-cadherin/CDH1, beta-catenin/CTNNB1 or gamma-catenin/JUP, and potentially alpha-catenin/CTNNA1. Forms a ternary complex composed of ADAM10, CADH1 and EPHA4,
null
null
KLRG1, SPEF1, DLGAP5, AJAP1, RAPGEF2, RAB8B, PIP5K1C, PKP2, TRPV4, CTNNB1, CAV1, DDR1, TBC1D2, CTNNA1, JUP, CTNND1, PSEN1, LIMA1, CDH1, JUP, ADAM10, CADH1 , EPHA4,
null
null
null
null
Homodimer
null
79.91949
0.474025
85.715777
0.339576
1,370
P12830
Q96FF9
null
degron_data
CDH1
MGPWSRSLSALLLLLQVSSWLCQEPEPCHPGFDAESYTFTVPRRHLERGRVLGRVNFEDCTGRQRTAYFSLDTRFKVGTDGVITVKRPLRFHNPQIHFLVYAWDSTYRKFSTKVTLNTVGHHHRPPPHQASVSGIQAELLTFPNSSPGLRRQKRDWVIPPISCPENEKGPFPKNLVQIKSNKDKEGKVFYSITGQGADTPPVGVFIIERETGWLKVTEPLDRERIATYTLFSHAVSSNGNAVEDPMEILITVTDQNDNKPEFTQEVFKGSVMEGALPGTSVMEVTATDADDDVNTYNAAIAYTILSQDPELPDKNMFTINRNTGVISVVTTGLDRESFPTYTLVVQAADLQGEGLSTTATAVITVTDTNDNPPIFNPTTYKGQVPENEANVVITTLKVTDADAPNTPAWEAVYTILNDDGGQFVVTTNPVNNDGILKTAKGLDFEAKQQYILHVAVTNVVPFEVSLTTSTATVTVDVLDVNEAPIFVPPEKRVEVSEDFGVGQEITSYTAQEPDTFMEQKITYRIWRDTANWLEINPDTGAISTRAELDREDFEHVKNSTYTALIIATDNGSPVATGTGTLLLILSDVNDNAPIPEPRTIFFCERNPKPQVINIIDADLPPNTSPFTAELTHGASANWTIQYNDPTQESIILKPKMALEVGDYKINLKLMDNQNKDQVTTLEVSVCDCEGAAGVCRKAQPVEAGLQIPAILGILGGILALLILILLLLLFLRRRAVVKEPLLPPEDDTRDNVYYYDEEGGGEEDQDFDLSQLHRGLDARPEVTRNDVAPTLMSVPRYLPRPANPDEIGNFIDENLKAADTDPTAPPYDSLLVFDYEGSGSEAASLSSLNSSESDKDQDYDYLNEWGNRFKKLADMYGGGEDD
Homo sapiens
Cell junction, adherens junction, Cell membrane, Endosome, Golgi apparatus, trans-Golgi network, Cytoplasm, Cell junction, desmosome
Tissue enhanced (parathyroid)
{'Ciliated cells': '119.1', 'Basal respiratory cells': '71.1', 'Club cells': '97.3', 'Ionocytes': '81.0', 'Mucus glandular cells': '155.0', 'Serous glandular cells': '67.8', 'Gastric mucus-secreting cells': '133.2', 'Proximal enterocytes': '140.9', 'Paneth cells': '125.1', 'Distal enterocytes': '307.5', 'Intestinal goblet cells': '173.5', 'Exocrine glandular cells': '-0.605', 'Basal prostatic cells': '68.3', 'Prostatic glandular cells': '186.7', 'Breast glandular cells': '0.773', 'Breast myoepithelial cells': '0.700', 'Glandular and luminal cells': '313.0', 'Secretory cells': '82.3', 'Basal keratinocytes': '102.5', 'Suprabasal keratinocytes': '162.6', 'Basal squamous epithelial cells': '51.0', 'Squamous epithelial cells': '106.9', 'Alveolar cells type 1': '0.437', 'Alveolar cells type 2': '0.706', 'Salivary duct cells': '95.9', 'Ductal cells': '0.541', 'Hepatocytes': '0.600', 'Cholangiocytes': '129.7', 'Proximal tubular cells': '0.042', 'Distal tubular cells': '0.0', 'Collecting duct cells': '143.9', 'Mesothelial cells': '0.799', 'Sertoli cells': '0.252', 'Granulosa cells': '12.9', 'Enteroendocrine cells': '92.4', 'Pancreatic endocrine cells': '78.1', 'Leydig cells': '0.264', 'Excitatory neurons': '0.7', 'Inhibitory neurons': '1.3', 'Cone photoreceptor cells': '0.0', 'Rod photoreceptor cells': '0.0', 'Bipolar cells': '0.2', 'Horizontal cells': '0.6', 'Astrocytes': '0.6', 'Oligodendrocyte precursor cells': '0.5', 'Oligodendrocytes': '29.9', 'Microglial cells': '0.9', 'Muller glia cells': '0.1', 'Schwann cells': '0.131', 'Spermatogonia': '0.392', 'Spermatocytes': '0.193', 'Early spermatids': '-0.217', 'Late spermatids': '-0.290', 'Oocytes': '16.9', 'Cytotrophoblasts': '119.2', 'Syncytiotrophoblasts': '45.0', 'Extravillous trophoblasts': '24.9', 'Endothelial cells': '6.1', 'Lymphatic endothelial cells': '0.4', 'Cardiomyocytes': '0.135', 'Skeletal myocytes': '0.107', 'Smooth muscle cells': '5.8', 'Adipocytes': '2.1', 'Melanocytes': '0.335', 'Fibroblasts': '6.5', 'Peritubular cells': '0.210', 'Endometrial stromal cells': '27.7', 'Ovarian stromal cells': '0.7', 'Undifferentiated cells': '101.6', 'T-cells': '2.9', 'B-cells': '4.4', 'Plasma cells': '6.1', 'Nk-cells': '0.0', 'Granulocytes': '8.4', 'Monocytes': '0.0', 'Macrophages': '6.0', 'Hofbauer cells': '4.3', 'Kupffer cells': '1.0', 'Dendritic cells': '5.9', 'Langerhans cells': '0.304', 'Erythroid cells': '0.036', 'Adipocytes (Subcutaneous)': '-0.081', 'Adipocytes (Visceral)': '-0.209', 'Breast glandular cells (progenitors)': '0.538', 'Adipocytes (Breast)': '-0.689', 'Colon enterocytes': '0.790', 'Colon enteroendocrine cells': '0.112', 'Enteric glia cells': '-0.048', 'Mitotic cells (Colon)': '0.299', 'Mitotic cells (Heart)': '0.120', 'Podocytes': '-0.118', 'Ascending Loop of Henle cells': '0.475', 'Intercalated cells': '0.212', 'Cholangiocyte': '0.090', 'NK-cells (Liver)': '-0.005', 'Respiratory ciliated cells': '-0.012', 'Mitotic cells (Lung)': '0.071', 'NK-cells (Lung)': '-0.266', 'B-cells (Lung)': '-0.296', 'Alpha cells': '0.270', 'Beta cells': '0.152', 'Prostate glandular cells': '0.764', 'Prostate basal glandular cells': '0.540', 'Urothelial cells': '0.205', 'Keratinocyte (other)': '0.510', 'Keratinocyte (granular)': '0.055', 'Hair cortex cells': '0.080', 'Inner root sheath cells': '0.131', 'Outer root sheath cells': '0.175', 'Sebaceous gland cells': '0.156', 'Eccrine sweat gland cells': '-0.207', 'Adipocytes (Skin)': '-0.244', 'Mitotic cells (Skin)': '0.442', 'Parietal cells': '0.654', 'Chief cells': '0.649', 'Gastric mucous cells': '0.781', 'Gastric enteroendocrine cells': '0.590', 'Mitotic cells (Stomach)': '0.445', 'Parafollicular cells': '0.173', 'Thyroid glandular cells': '0.865', 'Mitotic cells (Thyroid)': '-0.081', 'Adrenal cortex cells': '0.051', 'Adrenal medulla cells': '0.087', 'Mitotic cells (Adrenal gland)': '0.072', 'Minor salivary glandular cells': '0.371', 'Minor salivary gland ductal cells': '-0.142', 'Minor salivary gland basal cells': '0.582', 'Mitotic cells (Minor salivary gland)': '0.567', 'Adipocytes (Minor salivary gland)': '0.050', 'Somatotropes': '0.121', 'Lactotropes': '0.322', 'Gonadotropes': '0.330', 'Corticotropes': '0.180', 'Thyrotropes': '0.496', 'Undifferentiated cells (Pituitary gland)': '-0.108', 'Mitotic cells (Spleen)': '-0.228', 'Platelets': '-0.050', 'Erythrocytes': '-0.158', 'Hematopoietic stem cells': '-0.211', 'B-cells (Spleen)': '0.266', 'NK-cells (Spleen)': '0.309', 'Amygdala excitatory': '1.0', 'Cerebellar inhibitory': '0.9', 'Cge interneuron': '0.7', 'Deep-layer corticothalamic and 6b': '1.5', 'Deep-layer intratelencephalic': '0.7', 'Deep-layer near-projecting': '0.7', 'Eccentric medium spiny neuron': '0.6', 'Hippocampal ca1-3': '1.9', 'Hippocampal ca4': '1.2', 'Hippocampal dentate gyrus': '1.1', 'Lamp5-lhx6 and chandelier': '0.5', 'Lower rhombic lip': '0.8', 'Mammillary body': '0.6', 'Medium spiny neuron': '0.7', 'Mge interneuron': '1.7', 'Midbrain-derived inhibitory': '0.7', 'Miscellaneous': '0.9', 'Splatter': '3.8', 'Thalamic excitatory': '0.5', 'Upper rhombic lip': '0.8', 'Upper-layer intratelencephalic': '0.6', 'Astrocyte': '4.4', 'Bergmann glia': '0.2', 'Central nervous system macrophage': '0.6', 'Choroid plexus epithelial cell': '52.1', 'Committed oligodendrocyte precursor': '41.5', 'Ependymal cell': '4.8', 'Oligodendrocyte': '53.1', 'Oligodendrocyte precursor cell': '2.4', 'Endothelial cell': '0.7', 'Pericyte': '0.3', 'Vascular associated smooth muscle cell': '0.0', 'Fibroblast': '17.4', 'Leukocyte': '1.1', 'Basophil': '0.0', 'Eosinophil': '0.0', 'Neutrophil': '0.0', 'Classical monocyte': '0.0', 'Non-classical monocyte': '0.0', 'Intermediate monocyte': '0.0', 'T-reg': '2.3', 'GdT-cell': '0.0', 'MAIT T-cell': '0.0', 'Memory CD4 T-cell': '0.0', 'Naive CD4 T-cell': '0.1', 'Memory CD8 T-cell': '0.2', 'Naive CD8 T-cell': '0.3', 'Memory B-cell': '0.0', 'Naive B-cell': '0.1', 'Plasmacytoid DC': '46.6', 'Myeloid DC': '8.5', 'NK-cell': '0.1', 'Total PBMC': '0.7', 'Vd2 gdTCR': '0.0', 'Memory CD4 T-cell Th1\\/Th17': '0.1', 'Memory CD4 T-cell Th17': '0.2', 'Memory CD4 T-cell Th2': '2.9', 'Non-Vd2 gdTCR': '0.1', 'Memory CD4 T-cell Th1': '0.3', 'Memory CD4 T-cell TFH': '0.5', 'Terminal effector memory CD4 T-cell': '0.0', 'Central memory CD8 T-cell': '4.8', 'Effector memory CD8 T-cell': '0.0', 'Terminal effector memory CD8 T-cell': '0.6', 'Non-switched memory B-cell': '0.0', 'Plasmablast': '3.3', 'Switched memory B-cell': '0.0', 'Exhausted memory B-cell': '0.7', 'Progenitor cell': '2.3', 'Memory T-reg': '1.3', 'Naive CD4 T-cell activated': '0.3', 'Naive CD8 T-cell activated': '0.6', 'Naive T-reg': '0.1'}
1O6S, 2O72, 2OMT, 2OMU, 2OMV, 2OMX, 2OMY, 2OMZ, 3FF7, 3FF8, 3L6X, 3L6Y, 4ZT1, 4ZTE, 6CXY, 6OLE, 6OLF, 6OLG, 6VEL, 7STZ, 8H62
{'Adipose Tissue': 1.2125261088039867, 'Adrenal Gland': 0.1914223992248062, 'Bladder': 39.2033519047619, 'Blood': 1.340954264800861, 'Blood Vessel': 0.3121561692883895, 'Brain': 0.8550442199091597, 'Breast': 38.54918344226579, 'Cervix Uteri': 23.539115789473684, 'Colon': 43.41292142490372, 'Esophagus': 53.97513367404844, 'Fallopian Tube': 14.900277777777776, 'Heart': 0.119140469221835, 'Kidney': 25.040449438202245, 'Liver': 26.60802654867257, 'Lung': 35.447986366782004, 'Muscle': 0.1378936151930261, 'Nerve': 17.518468982229404, 'Ovary': 3.6515122222222223, 'Pancreas': 56.89676829268293, 'Pituitary': 24.68741660777385, 'Prostate': 61.279967346938776, 'Salivary Gland': 92.01685185185184, 'Skin': 79.77571720232172, 'Small Intestine': 71.7519320855615, 'Spleen': 10.061029045643156, 'Stomach': 58.07813805013927, 'Testis': 0.8144204986149585, 'Thyroid': 135.176797856049, 'Uterus': 1.442593943661972, 'Vagina': 86.52345512820513}
CDCA5
MSGRRTRSGGAAQRSGPRAPSPTKPLRRSQRKSGSELPSILPEIWPKTPSAAAVRKPIVLKRIVAHAVEVPAVQSPRRSPRISFFLEKENEPPGRELTKEDLFKTHSVPATPTSTPVPNPEAESSSKEGELDARDLEMSKKVRRSYSRLETLGSASTSTPGRRSCFGFEGLLGAEDLSGVSPVVCSKLTEVPRVCAKPWAPDMTLPGISPPPEKQKRKKKKMPEILKTELDEWAAAMNAEFEAAEQFDLLVE
Homo sapiens
Nucleus, Chromosome, Cytoplasm
Group enriched (bone marrow, lymphoid tissue, testis)
{'Ciliated cells': '0.7', 'Basal respiratory cells': '1.3', 'Club cells': '0.9', 'Ionocytes': '0.4', 'Mucus glandular cells': '0.9', 'Serous glandular cells': '2.5', 'Gastric mucus-secreting cells': '1.2', 'Proximal enterocytes': '0.6', 'Paneth cells': '1.2', 'Distal enterocytes': '0.5', 'Intestinal goblet cells': '4.3', 'Exocrine glandular cells': '-0.397', 'Basal prostatic cells': '0.1', 'Prostatic glandular cells': '0.4', 'Breast glandular cells': '0.326', 'Breast myoepithelial cells': '0.296', 'Glandular and luminal cells': '1.5', 'Secretory cells': '0.5', 'Basal keratinocytes': '5.1', 'Suprabasal keratinocytes': '1.6', 'Basal squamous epithelial cells': '2.9', 'Squamous epithelial cells': '6.0', 'Alveolar cells type 1': '-0.268', 'Alveolar cells type 2': '0.184', 'Salivary duct cells': '1.1', 'Ductal cells': '0.530', 'Hepatocytes': '0.341', 'Cholangiocytes': '0.0', 'Proximal tubular cells': '0.178', 'Distal tubular cells': '0.0', 'Collecting duct cells': '0.0', 'Mesothelial cells': '-0.080', 'Sertoli cells': '-0.438', 'Granulosa cells': '1.7', 'Enteroendocrine cells': '1.0', 'Pancreatic endocrine cells': '3.4', 'Leydig cells': '-0.481', 'Excitatory neurons': '1.0', 'Inhibitory neurons': '0.6', 'Cone photoreceptor cells': '1.7', 'Rod photoreceptor cells': '0.1', 'Bipolar cells': '0.3', 'Horizontal cells': '3.1', 'Astrocytes': '0.0', 'Oligodendrocyte precursor cells': '0.0', 'Oligodendrocytes': '0.6', 'Microglial cells': '0.9', 'Muller glia cells': '0.3', 'Schwann cells': '0.117', 'Spermatogonia': '-0.116', 'Spermatocytes': '0.265', 'Early spermatids': '0.713', 'Late spermatids': '0.466', 'Oocytes': '10.3', 'Cytotrophoblasts': '21.3', 'Syncytiotrophoblasts': '5.9', 'Extravillous trophoblasts': '38.9', 'Endothelial cells': '1.7', 'Lymphatic endothelial cells': '0.3', 'Cardiomyocytes': '0.486', 'Skeletal myocytes': '-0.098', 'Smooth muscle cells': '1.0', 'Adipocytes': '1.1', 'Melanocytes': '0.509', 'Fibroblasts': '2.5', 'Peritubular cells': '-0.346', 'Endometrial stromal cells': '1.3', 'Ovarian stromal cells': '0.4', 'Undifferentiated cells': '22.5', 'T-cells': '2.8', 'B-cells': '1.8', 'Plasma cells': '21.1', 'Nk-cells': '2.4', 'Granulocytes': '0.5', 'Monocytes': '0.2', 'Macrophages': '2.4', 'Hofbauer cells': '8.4', 'Kupffer cells': '2.8', 'Dendritic cells': '0.4', 'Langerhans cells': '0.213', 'Erythroid cells': '0.056', 'Adipocytes (Subcutaneous)': '-0.100', 'Adipocytes (Visceral)': '0.035', 'Breast glandular cells (progenitors)': '0.294', 'Adipocytes (Breast)': '-0.282', 'Colon enterocytes': '0.306', 'Colon enteroendocrine cells': '-0.118', 'Enteric glia cells': '-0.330', 'Mitotic cells (Colon)': '0.659', 'Mitotic cells (Heart)': '0.763', 'Podocytes': '-0.264', 'Ascending Loop of Henle cells': '0.383', 'Intercalated cells': '-0.134', 'Cholangiocyte': '0.314', 'NK-cells (Liver)': '-0.197', 'Respiratory ciliated cells': '0.006', 'Mitotic cells (Lung)': '0.876', 'NK-cells (Lung)': '-0.173', 'B-cells (Lung)': '-0.029', 'Alpha cells': '0.235', 'Beta cells': '0.115', 'Prostate glandular cells': '-0.030', 'Prostate basal glandular cells': '0.267', 'Urothelial cells': '0.218', 'Keratinocyte (other)': '0.275', 'Keratinocyte (granular)': '-0.200', 'Hair cortex cells': '0.098', 'Inner root sheath cells': '0.214', 'Outer root sheath cells': '0.228', 'Sebaceous gland cells': '0.121', 'Eccrine sweat gland cells': '-0.077', 'Adipocytes (Skin)': '-0.195', 'Mitotic cells (Skin)': '0.840', 'Parietal cells': '-0.099', 'Chief cells': '-0.066', 'Gastric mucous cells': '0.379', 'Gastric enteroendocrine cells': '0.051', 'Mitotic cells (Stomach)': '0.911', 'Parafollicular cells': '-0.047', 'Thyroid glandular cells': '-0.023', 'Mitotic cells (Thyroid)': '0.598', 'Adrenal cortex cells': '0.393', 'Adrenal medulla cells': '0.112', 'Mitotic cells (Adrenal gland)': '0.915', 'Minor salivary glandular cells': '0.226', 'Minor salivary gland ductal cells': '-0.298', 'Minor salivary gland basal cells': '0.659', 'Mitotic cells (Minor salivary gland)': '0.928', 'Adipocytes (Minor salivary gland)': '0.186', 'Somatotropes': '-0.041', 'Lactotropes': '-0.226', 'Gonadotropes': '-0.050', 'Corticotropes': '-0.218', 'Thyrotropes': '-0.122', 'Undifferentiated cells (Pituitary gland)': '0.389', 'Mitotic cells (Spleen)': '0.911', 'Platelets': '0.190', 'Erythrocytes': '0.316', 'Hematopoietic stem cells': '0.372', 'B-cells (Spleen)': '-0.121', 'NK-cells (Spleen)': '-0.269', 'Amygdala excitatory': '0.5', 'Cerebellar inhibitory': '0.9', 'Cge interneuron': '0.4', 'Deep-layer corticothalamic and 6b': '0.9', 'Deep-layer intratelencephalic': '1.0', 'Deep-layer near-projecting': '0.8', 'Eccentric medium spiny neuron': '0.4', 'Hippocampal ca1-3': '1.0', 'Hippocampal ca4': '0.6', 'Hippocampal dentate gyrus': '0.5', 'Lamp5-lhx6 and chandelier': '0.4', 'Lower rhombic lip': '1.6', 'Mammillary body': '0.7', 'Medium spiny neuron': '0.4', 'Mge interneuron': '0.6', 'Midbrain-derived inhibitory': '0.7', 'Miscellaneous': '1.2', 'Splatter': '0.6', 'Thalamic excitatory': '0.9', 'Upper rhombic lip': '1.3', 'Upper-layer intratelencephalic': '1.0', 'Astrocyte': '0.3', 'Bergmann glia': '0.2', 'Central nervous system macrophage': '0.3', 'Choroid plexus epithelial cell': '0.3', 'Committed oligodendrocyte precursor': '0.6', 'Ependymal cell': '0.2', 'Oligodendrocyte': '0.5', 'Oligodendrocyte precursor cell': '0.3', 'Endothelial cell': '0.3', 'Pericyte': '0.0', 'Vascular associated smooth muscle cell': '0.2', 'Fibroblast': '0.5', 'Leukocyte': '0.1', 'Basophil': '0.8', 'Eosinophil': '0.2', 'Neutrophil': '0.8', 'Classical monocyte': '0.2', 'Non-classical monocyte': '0.5', 'Intermediate monocyte': '0.3', 'T-reg': '4.9', 'GdT-cell': '0.4', 'MAIT T-cell': '0.3', 'Memory CD4 T-cell': '0.5', 'Naive CD4 T-cell': '0.4', 'Memory CD8 T-cell': '0.3', 'Naive CD8 T-cell': '0.3', 'Memory B-cell': '0.3', 'Naive B-cell': '0.5', 'Plasmacytoid DC': '1.6', 'Myeloid DC': '0.9', 'NK-cell': '2.2', 'Total PBMC': '2.4', 'Vd2 gdTCR': '0.2', 'Memory CD4 T-cell Th1\\/Th17': '0.3', 'Memory CD4 T-cell Th17': '0.6', 'Memory CD4 T-cell Th2': '0.7', 'Non-Vd2 gdTCR': '1.0', 'Memory CD4 T-cell Th1': '1.3', 'Memory CD4 T-cell TFH': '0.4', 'Terminal effector memory CD4 T-cell': '0.0', 'Central memory CD8 T-cell': '0.5', 'Effector memory CD8 T-cell': '3.2', 'Terminal effector memory CD8 T-cell': '0.9', 'Non-switched memory B-cell': '0.6', 'Plasmablast': '37.6', 'Switched memory B-cell': '1.3', 'Exhausted memory B-cell': '9.5', 'Progenitor cell': '3.1', 'Memory T-reg': '4.7', 'Naive CD4 T-cell activated': '0.7', 'Naive CD8 T-cell activated': '0.7', 'Naive T-reg': '0.6'}
null
{'Adipose Tissue': 1.315615365448505, 'Adrenal Gland': 1.4035717054263566, 'Bladder': 1.4172333333333331, 'Blood': 14.750220139935411, 'Blood Vessel': 0.8903569288389513, 'Brain': 1.2125449394398182, 'Breast': 1.2887961220043571, 'Cervix Uteri': 1.886715789473684, 'Colon': 2.7703213093709884, 'Esophagus': 4.611380256055363, 'Fallopian Tube': 1.1682777777777775, 'Heart': 0.5252589547038328, 'Kidney': 0.937823595505618, 'Liver': 0.8826044247787611, 'Lung': 3.2854162629757786, 'Muscle': 0.4393217310087173, 'Nerve': 0.9960046849757672, 'Ovary': 1.2204616666666666, 'Pancreas': 0.3526619512195121, 'Pituitary': 0.8254855123674912, 'Prostate': 1.3771114285714283, 'Salivary Gland': 1.9042814814814817, 'Skin': 10.058297346600332, 'Small Intestine': 5.629671122994652, 'Spleen': 8.386151452282158, 'Stomach': 2.461782506963788, 'Testis': 53.67396121883656, 'Thyroid': 1.1105546248085758, 'Uterus': 1.2081598591549294, 'Vagina': 4.175232692307692}
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84.0, 78.55, 77.54, 79.14, 71.75, 66.9, 66.04, 62.08, 52.01, 41.0, 35.6, 37.99, 32.58, 39.91, 39.79, 37.8, 44.59, 49.28, 45.67, 43.32, 44.39, 42.75, 44.8, 45.61, 41.87, 40.9, 44.22, 44.93, 40.58, 34.47, 36.28, 42.64, 44.81, 36.33, 37.53, 36.55, 31.88, 33.61, 36.71, 43.22, 40.36, 45.92, 43.97, 47.37, 48.95, 46.84, 42.64, 43.69, 43.17, 45.27, 43.14, 41.56, 39.85, 44.48, 49.34, 48.03, 44.76, 46.26, 45.11, 52.26, 47.51, 49.58, 50.31, 52.17, 53.06, 54.47, 55.5, 57.89, 57.56, 59.79, 65.12, 66.93, 68.41, 70.79, 67.57, 68.53, 69.64, 67.58, 66.04, 66.79, 65.01, 69.78, 73.95, 76.55, 76.71, 72.44, 76.54, 75.85, 74.76, 74.72, 76.36, 75.07, 67.72, 67.37, 69.16, 70.0, 61.64, 63.7, 57.89, 54.12, 47.37, 44.62, 41.93, 41.5, 42.58, 44.57, 44.28, 39.27, 41.11, 39.96, 41.73, 41.86, 35.69, 45.09, 38.03, 44.0, 44.36, 42.28, 41.43, 39.83, 40.51, 40.5, 35.5, 43.19, 34.98, 38.91, 47.07, 47.66, 45.04, 52.1, 53.63, 54.74, 60.8, 66.6, 67.38, 73.78, 70.69, 71.39, 73.71, 71.26, 75.83, 77.11, 78.67, 73.71, 72.61, 73.27, 70.36, 72.63, 72.69, 68.11, 66.06, 60.67, 52.64, 44.07, 48.46, 43.79, 36.31]
[1.0, 1.0, 1.0, 1.0, 0.98, 1.0, 0.91, 0.96, 0.9, 0.88, 1.0, 1.0, 1.0, 1.0, 1.0, 0.87, 0.99, 0.76, 0.96, 1.0, 0.98, 0.95, 0.93, 0.92, 0.87, 0.92, 0.69, 0.71, 0.79, 0.3, 0.2, 0.17, 0.63, 0.32, 0.89, 0.66, 0.1, 0.62, 0.15, 0.67, 0.03, 0.67, 0.77, 0.54, 0.57, 0.04, 0.68, 0.73, 0.54, 0.54, 0.59, 0.08, 0.19, 0.61, 0.0, 0.39, 0.06, 0.63, 0.14, 0.63, 0.49, 0.83, 0.72, 0.93, 0.78, 0.07, 0.63, 0.12, 0.52, 0.15, 0.6, 0.19, 0.51, 0.41, 0.03, 0.62, 0.11, 0.3, 0.46, 0.47, 0.0, 0.23, 0.0, 0.24, 0.03, 0.5, 0.67, 0.61, 0.06, 0.78, 0.04, 0.83, 0.7, 0.57, 0.54, 0.13, 0.52, 0.06, 0.45, 0.0, 0.11, 0.0, 0.38, 0.12, 0.54, 0.79, 0.81, 0.65, 0.6, 0.24, 0.6, 0.01, 0.47, 0.01, 0.12, 0.0, 0.25, 0.26, 0.46, 0.93, 0.85, 0.99, 0.94, 1.0, 0.91, 0.99, 0.99, 0.98, 1.0, 1.0, 1.0, 1.0, 0.99, 0.98, 0.98, 0.92, 0.93, 0.87, 0.82, 0.85, 0.76, 0.9, 0.91, 0.9, 0.93, 0.65, 0.96, 0.84, 0.86, 0.96, 0.99, 0.96, 0.7, 0.92, 0.89, 0.8, 0.83, 0.23, 0.86, 0.73, 0.12, 0.62, 0.06, 0.4, 0.02, 0.42, 0.35, 0.9, 0.64, 0.82, 0.29, 0.51, 0.17, 0.54, 0.27, 0.29, 0.51, 0.08, 0.77, 0.06, 0.62, 0.39, 0.34, 0.94, 0.83, 0.46, 0.51, 0.07, 0.17, 0.07, 0.41, 0.14, 0.31, 0.2, 0.36, 0.0, 0.13, 0.59, 0.53, 0.77, 0.2, 0.64, 0.35, 0.0, 0.02, 0.39, 0.18, 0.39, 0.57, 0.63, 0.39, 0.0, 0.32, 0.0, 0.18, 0.03, 0.29, 0.47, 0.55, 0.03, 0.34, 0.2, 0.45, 0.56, 0.17, 0.37, 0.59, 0.01, 0.39, 0.0, 0.39, 0.05, 0.28, 0.07, 0.29, 0.26, 0.64, 0.82, 0.64, 0.63, 0.76, 0.15, 0.39, 0.95, 0.57, 0.28, 0.58, 0.02, 0.43, 0.0, 0.29, 0.09, 0.4, 0.13, 0.49, 0.31, 0.53, 0.32, 0.66, 0.01, 0.71, 0.13, 0.56, 0.54, 0.84, 0.51, 0.06, 0.82, 0.14, 0.54, 0.07, 0.63, 0.05, 0.7, 0.17, 0.75, 0.51, 0.64, 0.36, 0.67, 0.15, 0.12, 0.61, 0.0, 0.33, 0.14, 0.62, 0.2, 0.52, 0.05, 0.14, 0.63, 0.95, 0.85, 0.32, 0.6, 0.1, 0.12, 0.17, 0.17, 0.06, 0.08, 0.41, 0.28, 0.55, 0.49, 0.09, 0.68, 0.23, 0.53, 0.64, 0.52, 0.42, 0.64, 0.64, 0.0, 0.08, 0.44, 0.13, 0.48, 0.52, 0.81, 0.44, 0.0, 0.26, 0.0, 0.21, 0.03, 0.46, 0.27, 0.71, 0.45, 0.06, 0.28, 0.28, 0.4, 0.65, 0.28, 0.46, 0.61, 0.0, 0.36, 0.0, 0.32, 0.01, 0.22, 0.0, 0.05, 0.0, 0.41, 0.46, 0.42, 0.82, 0.48, 0.4, 0.5, 0.17, 0.62, 0.06, 0.32, 0.0, 0.25, 0.0, 0.42, 0.08, 0.41, 0.27, 0.16, 0.04, 0.36, 0.32, 0.2, 0.0, 0.52, 0.04, 0.66, 0.47, 0.52, 0.78, 0.09, 0.77, 0.08, 0.6, 0.0, 0.31, 0.03, 0.58, 0.47, 0.59, 0.44, 0.23, 0.54, 0.1, 0.18, 0.45, 0.0, 0.53, 0.11, 0.59, 0.17, 0.51, 0.01, 0.19, 0.71, 0.77, 0.3, 0.44, 0.08, 0.14, 0.52, 0.05, 0.37, 0.1, 0.42, 0.23, 0.61, 0.43, 0.22, 0.96, 0.54, 0.4, 0.3, 0.07, 0.39, 0.17, 0.43, 0.38, 0.3, 0.8, 0.83, 0.44, 0.03, 0.11, 0.0, 0.23, 0.0, 0.31, 0.0, 0.38, 0.58, 0.51, 0.01, 0.49, 0.13, 0.26, 0.69, 0.46, 0.41, 0.51, 0.06, 0.51, 0.03, 0.38, 0.0, 0.06, 0.0, 0.34, 0.08, 0.53, 0.42, 0.88, 0.25, 0.75, 0.49, 1.0, 0.34, 0.86, 0.48, 0.18, 0.52, 0.01, 0.32, 0.0, 0.19, 0.0, 0.3, 0.05, 0.44, 0.27, 0.43, 0.11, 0.31, 0.39, 0.03, 0.55, 0.04, 0.52, 0.51, 0.64, 0.57, 0.19, 0.68, 0.13, 0.84, 0.06, 0.31, 0.07, 0.69, 0.26, 0.37, 0.53, 0.67, 0.5, 0.56, 0.14, 0.18, 0.47, 0.01, 0.47, 0.15, 0.61, 0.28, 0.2, 0.02, 0.76, 0.55, 0.31, 0.94, 0.22, 0.57, 0.17, 0.4, 0.07, 0.5, 0.31, 0.7, 0.2, 0.14, 0.3, 0.23, 0.58, 0.07, 0.06, 0.55, 0.15, 0.46, 0.43, 0.64, 0.53, 0.0, 0.18, 0.01, 0.23, 0.02, 0.63, 0.33, 0.79, 0.06, 0.38, 0.07, 0.14, 0.23, 0.68, 0.89, 0.29, 0.06, 0.72, 0.92, 0.24, 0.25, 0.0, 0.46, 0.02, 0.21, 0.01, 0.06, 0.0, 0.05, 0.07, 0.61, 0.17, 0.89, 0.72, 0.66, 0.14, 0.52, 0.07, 0.58, 0.01, 0.26, 0.0, 0.13, 0.0, 0.29, 0.04, 0.46, 0.27, 0.28, 0.23, 0.56, 0.32, 0.25, 0.0, 0.33, 0.05, 0.55, 0.5, 0.58, 0.53, 0.04, 0.27, 0.02, 0.04, 0.37, 0.67, 0.74, 0.35, 0.62, 0.54, 0.26, 0.46, 0.0, 0.47, 0.09, 0.45, 0.15, 0.39, 0.05, 0.44, 0.85, 0.56, 0.11, 0.11, 0.35, 0.42, 0.03, 0.32, 0.12, 0.49, 0.19, 0.25, 0.8, 0.6, 0.09, 0.49, 0.57, 0.36, 0.04, 0.35, 0.28, 0.52, 0.39, 0.5, 0.28, 0.93, 0.47, 0.3, 0.47, 0.08, 0.02, 0.18, 0.01, 0.34, 0.23, 0.55, 0.57, 0.91, 0.1, 0.78, 0.52, 0.34, 0.61, 0.24, 0.75, 0.0, 0.2, 0.02, 0.24, 0.0, 0.18, 0.04, 0.44, 0.59, 0.71, 0.29, 0.52, 0.37, 0.5, 0.11, 0.6, 0.02, 0.48, 0.01, 0.16, 0.04, 0.35, 0.66, 0.47, 0.74, 0.14, 0.62, 0.16, 0.77, 0.79, 0.27, 0.93, 0.69, 0.88, 0.88, 0.85, 0.87, 0.91, 0.92, 0.82, 0.63, 0.75, 0.7, 0.7, 0.38, 0.43, 0.64, 0.55, 0.54, 0.59, 0.45, 0.47, 0.5, 0.58, 0.52, 0.61, 0.57, 0.52, 0.68, 0.44, 0.6, 0.61, 0.58, 0.55, 0.5, 0.61, 0.61, 0.86, 0.86, 0.75, 0.91, 0.96, 0.93, 1.0, 0.87, 0.97, 0.91, 0.95, 0.86, 0.98, 0.93, 0.88, 0.59, 0.87, 0.7, 0.67, 0.85, 0.89, 0.88, 0.91, 0.93, 0.88, 0.99, 0.92, 1.0, 0.79, 0.9, 1.0, 0.94, 1.0, 0.97, 0.96, 0.9, 0.63, 0.68, 0.48, 0.54, 0.8, 0.7, 0.7, 0.95, 0.87, 0.77, 0.84, 0.79, 0.89, 0.95, 0.8, 0.77, 0.51, 0.87, 0.7, 0.52, 0.84, 0.91, 0.51, 0.96, 0.79, 0.92, 0.84, 0.21, 0.89, 0.53, 0.52, 0.89, 0.86, 0.26, 0.91, 0.45, 0.68, 0.84, 0.48, 0.44, 0.51, 0.62, 0.28, 0.59, 0.63, 0.57, 0.15, 0.55, 0.66, 0.1, 0.38, 0.74, 0.65, 0.17, 0.43, 0.66, 0.41, 0.8, 0.75, 0.9, 0.93, 0.52, 0.76, 0.89, 0.87, 0.76, 0.92, 0.91, 0.75, 0.61, 0.96, 0.89, 0.73, 0.97, 0.68, 0.87, 0.55, 0.85, 0.77, 0.69, 0.76, 0.98, 0.83, 0.68, 0.82, 0.74, 0.65, 0.96, 0.93, 0.54, 0.64, 0.28, 0.54, 0.52, 0.16, 0.51, 0.88, 0.6, 0.4, 0.88, 0.95, 0.33, 0.56, 0.73, 0.39, 0.06, 0.61, 0.75, 0.47, 0.19, 0.87, 0.7, 0.97, 0.94, 0.97]
[50.46, 54.35, 45.02, 68.55, 56.92, 69.24, 64.22, 56.66, 61.43, 52.77, 57.28, 55.02, 56.64, 52.55, 59.49, 53.89, 51.28, 52.89, 57.12, 53.17, 53.18, 49.9, 53.83, 65.49, 57.22, 54.08, 55.71, 55.95, 66.28, 55.25, 58.89, 55.71, 55.55, 45.91, 54.7, 47.91, 62.15, 56.3, 44.2, 47.63, 61.49, 62.32, 47.12, 56.4, 52.13, 50.33, 49.78, 53.95, 53.48, 56.11, 53.1, 53.6, 62.01, 62.11, 69.93, 78.85, 76.46, 79.57, 81.08, 83.47, 83.05, 81.43, 75.3, 79.39, 74.56, 75.18, 68.86, 69.09, 62.74, 62.51, 66.28, 58.83, 58.05, 56.42, 57.65, 57.08, 52.04, 59.98, 60.56, 55.09, 63.38, 62.25, 62.67, 61.74, 52.68, 60.96, 55.53, 60.41, 53.36, 55.04, 55.32, 54.93, 48.37, 43.32, 50.81, 40.03, 54.57, 42.77, 46.53, 51.71, 45.23, 51.27, 46.0, 53.27, 47.47, 48.15, 52.22, 58.11, 60.83, 54.29, 49.72, 62.98, 48.68, 42.62, 50.78, 62.12, 50.37, 52.74, 50.11, 51.87, 41.7, 43.87, 40.81, 43.81, 38.21, 48.33, 51.87, 48.32, 61.41, 65.53, 69.61, 81.11, 85.98, 86.97, 84.43, 82.89, 85.12, 81.24, 79.53, 82.06, 85.36, 81.11, 79.98, 73.46, 74.47, 64.18, 64.99, 68.09, 63.46, 62.64, 58.39, 53.66, 53.06, 52.49, 52.75, 51.42, 57.71, 51.3, 57.72, 56.91, 63.56, 62.8, 69.69, 69.75, 72.41, 79.39, 72.52, 73.21, 71.77, 66.23, 65.71, 63.01, 57.43, 58.01, 60.25, 58.81, 62.84, 61.44, 61.19, 57.13, 60.15, 67.22, 64.07, 55.26, 47.63, 54.23, 56.05, 50.7, 49.96, 44.63, 53.66, 47.32, 40.81, 45.77, 37.79, 52.02, 61.69, 57.2, 54.88, 67.91, 71.19, 71.04, 76.48, 77.87, 79.5, 83.99, 78.43, 75.47, 69.56, 69.9, 66.88, 61.76, 58.7, 57.41, 57.4, 57.42, 58.37, 60.98, 63.54, 66.69, 69.46, 65.32, 71.38, 77.68, 79.17, 83.69, 85.86, 87.03, 90.15, 92.33, 93.17, 91.55, 94.41, 94.06, 94.01, 94.17, 94.7, 92.63, 91.6, 88.47, 89.55, 87.6, 84.65, 84.37, 84.34, 81.64, 76.67, 77.35, 80.31, 76.96, 77.8, 75.19]
[0.99, 0.99, 0.98, 0.98, 0.96, 0.98, 0.96, 0.99, 1.0, 1.0, 0.93, 0.98, 0.95, 0.99, 1.0, 1.0, 1.0, 1.0, 1.0, 0.98, 0.88, 0.97, 0.89, 0.95, 0.96, 0.95, 0.97, 0.9, 0.92, 0.73, 0.89, 0.87, 0.82, 0.98, 0.82, 0.99, 0.89, 0.79, 0.83, 0.84, 0.85, 0.78, 0.79, 0.86, 0.82, 0.92, 0.92, 0.86, 0.91, 0.84, 0.86, 0.79, 0.79, 0.84, 0.92, 0.88, 0.84, 0.82, 0.82, 0.86, 0.88, 0.9, 0.92, 0.82, 0.92, 0.85, 0.9, 0.72, 0.94, 0.81, 0.79, 0.87, 0.78, 0.93, 0.82, 0.95, 0.97, 0.97, 0.93, 0.89, 0.91, 0.74, 0.66, 0.83, 0.87, 0.83, 0.94, 0.87, 0.97, 0.91, 0.99, 0.94, 0.99, 0.94, 0.93, 0.91, 0.89, 0.7, 0.97, 0.87, 0.93, 0.97, 0.94, 0.92, 0.95, 0.91, 0.88, 0.92, 0.93, 0.86, 0.95, 0.92, 0.9, 0.93, 0.83, 0.91, 0.92, 0.86, 0.88, 0.82, 0.86, 0.63, 0.89, 0.73, 0.91, 0.87, 0.97, 0.94, 0.65, 0.94, 0.68, 0.54, 0.68, 0.71, 0.5, 0.5, 0.53, 0.47, 0.54, 0.84, 0.61, 0.36, 0.81, 0.9, 0.62, 0.63, 0.64, 0.81, 0.78, 0.78, 0.86, 0.62, 0.91, 0.92, 0.44, 0.63, 0.95, 0.55, 0.62, 0.94, 0.97, 0.72, 0.86, 0.4, 0.89, 0.77, 0.67, 0.55, 0.64, 0.66, 0.48, 0.86, 0.42, 0.94, 0.83, 0.75, 0.56, 0.84, 0.85, 0.7, 0.58, 0.88, 0.64, 0.87, 0.75, 0.85, 0.91, 0.98, 0.92, 1.0, 0.99, 0.94, 1.0, 0.89, 0.95, 0.82, 0.93, 0.87, 0.91, 0.83, 0.72, 0.44, 0.55, 0.84, 0.62, 0.96, 0.94, 0.45, 0.88, 0.75, 0.76, 0.78, 0.89, 0.9, 0.74, 0.92, 0.85, 0.89, 0.91, 0.92, 0.93, 0.89, 0.84, 0.84, 0.49, 0.65, 0.79, 0.58, 0.38, 0.58, 0.64, 0.66, 0.52, 0.43, 0.53, 0.43, 0.7, 0.57, 0.5, 0.73, 0.69, 0.64, 0.6, 0.4, 0.71, 0.82, 0.66, 0.85, 0.74, 0.91, 0.81, 0.98]
null
Component of an E-cadherin/ catenin adhesion complex composed of at least E-cadherin/CDH1, beta-catenin/CTNNB1 or gamma-catenin/JUP, and potentially alpha-catenin/CTNNA1. Forms a ternary complex composed of ADAM10, CADH1 and EPHA4,
null
null
KLRG1, SPEF1, DLGAP5, AJAP1, RAPGEF2, RAB8B, PIP5K1C, PKP2, TRPV4, CTNNB1, CAV1, DDR1, TBC1D2, CTNNA1, JUP, CTNND1, PSEN1, LIMA1, CDH1, JUP, ADAM10, CADH1 , EPHA4,
null
null
null
null
Homodimer
null
79.91949
0.474025
63.132063
0.816071
2,553
P12830
Q96GD4
null
degron_data
CDH1
MGPWSRSLSALLLLLQVSSWLCQEPEPCHPGFDAESYTFTVPRRHLERGRVLGRVNFEDCTGRQRTAYFSLDTRFKVGTDGVITVKRPLRFHNPQIHFLVYAWDSTYRKFSTKVTLNTVGHHHRPPPHQASVSGIQAELLTFPNSSPGLRRQKRDWVIPPISCPENEKGPFPKNLVQIKSNKDKEGKVFYSITGQGADTPPVGVFIIERETGWLKVTEPLDRERIATYTLFSHAVSSNGNAVEDPMEILITVTDQNDNKPEFTQEVFKGSVMEGALPGTSVMEVTATDADDDVNTYNAAIAYTILSQDPELPDKNMFTINRNTGVISVVTTGLDRESFPTYTLVVQAADLQGEGLSTTATAVITVTDTNDNPPIFNPTTYKGQVPENEANVVITTLKVTDADAPNTPAWEAVYTILNDDGGQFVVTTNPVNNDGILKTAKGLDFEAKQQYILHVAVTNVVPFEVSLTTSTATVTVDVLDVNEAPIFVPPEKRVEVSEDFGVGQEITSYTAQEPDTFMEQKITYRIWRDTANWLEINPDTGAISTRAELDREDFEHVKNSTYTALIIATDNGSPVATGTGTLLLILSDVNDNAPIPEPRTIFFCERNPKPQVINIIDADLPPNTSPFTAELTHGASANWTIQYNDPTQESIILKPKMALEVGDYKINLKLMDNQNKDQVTTLEVSVCDCEGAAGVCRKAQPVEAGLQIPAILGILGGILALLILILLLLLFLRRRAVVKEPLLPPEDDTRDNVYYYDEEGGGEEDQDFDLSQLHRGLDARPEVTRNDVAPTLMSVPRYLPRPANPDEIGNFIDENLKAADTDPTAPPYDSLLVFDYEGSGSEAASLSSLNSSESDKDQDYDYLNEWGNRFKKLADMYGGGEDD
Homo sapiens
Cell junction, adherens junction, Cell membrane, Endosome, Golgi apparatus, trans-Golgi network, Cytoplasm, Cell junction, desmosome
Tissue enhanced (parathyroid)
{'Ciliated cells': '119.1', 'Basal respiratory cells': '71.1', 'Club cells': '97.3', 'Ionocytes': '81.0', 'Mucus glandular cells': '155.0', 'Serous glandular cells': '67.8', 'Gastric mucus-secreting cells': '133.2', 'Proximal enterocytes': '140.9', 'Paneth cells': '125.1', 'Distal enterocytes': '307.5', 'Intestinal goblet cells': '173.5', 'Exocrine glandular cells': '-0.605', 'Basal prostatic cells': '68.3', 'Prostatic glandular cells': '186.7', 'Breast glandular cells': '0.773', 'Breast myoepithelial cells': '0.700', 'Glandular and luminal cells': '313.0', 'Secretory cells': '82.3', 'Basal keratinocytes': '102.5', 'Suprabasal keratinocytes': '162.6', 'Basal squamous epithelial cells': '51.0', 'Squamous epithelial cells': '106.9', 'Alveolar cells type 1': '0.437', 'Alveolar cells type 2': '0.706', 'Salivary duct cells': '95.9', 'Ductal cells': '0.541', 'Hepatocytes': '0.600', 'Cholangiocytes': '129.7', 'Proximal tubular cells': '0.042', 'Distal tubular cells': '0.0', 'Collecting duct cells': '143.9', 'Mesothelial cells': '0.799', 'Sertoli cells': '0.252', 'Granulosa cells': '12.9', 'Enteroendocrine cells': '92.4', 'Pancreatic endocrine cells': '78.1', 'Leydig cells': '0.264', 'Excitatory neurons': '0.7', 'Inhibitory neurons': '1.3', 'Cone photoreceptor cells': '0.0', 'Rod photoreceptor cells': '0.0', 'Bipolar cells': '0.2', 'Horizontal cells': '0.6', 'Astrocytes': '0.6', 'Oligodendrocyte precursor cells': '0.5', 'Oligodendrocytes': '29.9', 'Microglial cells': '0.9', 'Muller glia cells': '0.1', 'Schwann cells': '0.131', 'Spermatogonia': '0.392', 'Spermatocytes': '0.193', 'Early spermatids': '-0.217', 'Late spermatids': '-0.290', 'Oocytes': '16.9', 'Cytotrophoblasts': '119.2', 'Syncytiotrophoblasts': '45.0', 'Extravillous trophoblasts': '24.9', 'Endothelial cells': '6.1', 'Lymphatic endothelial cells': '0.4', 'Cardiomyocytes': '0.135', 'Skeletal myocytes': '0.107', 'Smooth muscle cells': '5.8', 'Adipocytes': '2.1', 'Melanocytes': '0.335', 'Fibroblasts': '6.5', 'Peritubular cells': '0.210', 'Endometrial stromal cells': '27.7', 'Ovarian stromal cells': '0.7', 'Undifferentiated cells': '101.6', 'T-cells': '2.9', 'B-cells': '4.4', 'Plasma cells': '6.1', 'Nk-cells': '0.0', 'Granulocytes': '8.4', 'Monocytes': '0.0', 'Macrophages': '6.0', 'Hofbauer cells': '4.3', 'Kupffer cells': '1.0', 'Dendritic cells': '5.9', 'Langerhans cells': '0.304', 'Erythroid cells': '0.036', 'Adipocytes (Subcutaneous)': '-0.081', 'Adipocytes (Visceral)': '-0.209', 'Breast glandular cells (progenitors)': '0.538', 'Adipocytes (Breast)': '-0.689', 'Colon enterocytes': '0.790', 'Colon enteroendocrine cells': '0.112', 'Enteric glia cells': '-0.048', 'Mitotic cells (Colon)': '0.299', 'Mitotic cells (Heart)': '0.120', 'Podocytes': '-0.118', 'Ascending Loop of Henle cells': '0.475', 'Intercalated cells': '0.212', 'Cholangiocyte': '0.090', 'NK-cells (Liver)': '-0.005', 'Respiratory ciliated cells': '-0.012', 'Mitotic cells (Lung)': '0.071', 'NK-cells (Lung)': '-0.266', 'B-cells (Lung)': '-0.296', 'Alpha cells': '0.270', 'Beta cells': '0.152', 'Prostate glandular cells': '0.764', 'Prostate basal glandular cells': '0.540', 'Urothelial cells': '0.205', 'Keratinocyte (other)': '0.510', 'Keratinocyte (granular)': '0.055', 'Hair cortex cells': '0.080', 'Inner root sheath cells': '0.131', 'Outer root sheath cells': '0.175', 'Sebaceous gland cells': '0.156', 'Eccrine sweat gland cells': '-0.207', 'Adipocytes (Skin)': '-0.244', 'Mitotic cells (Skin)': '0.442', 'Parietal cells': '0.654', 'Chief cells': '0.649', 'Gastric mucous cells': '0.781', 'Gastric enteroendocrine cells': '0.590', 'Mitotic cells (Stomach)': '0.445', 'Parafollicular cells': '0.173', 'Thyroid glandular cells': '0.865', 'Mitotic cells (Thyroid)': '-0.081', 'Adrenal cortex cells': '0.051', 'Adrenal medulla cells': '0.087', 'Mitotic cells (Adrenal gland)': '0.072', 'Minor salivary glandular cells': '0.371', 'Minor salivary gland ductal cells': '-0.142', 'Minor salivary gland basal cells': '0.582', 'Mitotic cells (Minor salivary gland)': '0.567', 'Adipocytes (Minor salivary gland)': '0.050', 'Somatotropes': '0.121', 'Lactotropes': '0.322', 'Gonadotropes': '0.330', 'Corticotropes': '0.180', 'Thyrotropes': '0.496', 'Undifferentiated cells (Pituitary gland)': '-0.108', 'Mitotic cells (Spleen)': '-0.228', 'Platelets': '-0.050', 'Erythrocytes': '-0.158', 'Hematopoietic stem cells': '-0.211', 'B-cells (Spleen)': '0.266', 'NK-cells (Spleen)': '0.309', 'Amygdala excitatory': '1.0', 'Cerebellar inhibitory': '0.9', 'Cge interneuron': '0.7', 'Deep-layer corticothalamic and 6b': '1.5', 'Deep-layer intratelencephalic': '0.7', 'Deep-layer near-projecting': '0.7', 'Eccentric medium spiny neuron': '0.6', 'Hippocampal ca1-3': '1.9', 'Hippocampal ca4': '1.2', 'Hippocampal dentate gyrus': '1.1', 'Lamp5-lhx6 and chandelier': '0.5', 'Lower rhombic lip': '0.8', 'Mammillary body': '0.6', 'Medium spiny neuron': '0.7', 'Mge interneuron': '1.7', 'Midbrain-derived inhibitory': '0.7', 'Miscellaneous': '0.9', 'Splatter': '3.8', 'Thalamic excitatory': '0.5', 'Upper rhombic lip': '0.8', 'Upper-layer intratelencephalic': '0.6', 'Astrocyte': '4.4', 'Bergmann glia': '0.2', 'Central nervous system macrophage': '0.6', 'Choroid plexus epithelial cell': '52.1', 'Committed oligodendrocyte precursor': '41.5', 'Ependymal cell': '4.8', 'Oligodendrocyte': '53.1', 'Oligodendrocyte precursor cell': '2.4', 'Endothelial cell': '0.7', 'Pericyte': '0.3', 'Vascular associated smooth muscle cell': '0.0', 'Fibroblast': '17.4', 'Leukocyte': '1.1', 'Basophil': '0.0', 'Eosinophil': '0.0', 'Neutrophil': '0.0', 'Classical monocyte': '0.0', 'Non-classical monocyte': '0.0', 'Intermediate monocyte': '0.0', 'T-reg': '2.3', 'GdT-cell': '0.0', 'MAIT T-cell': '0.0', 'Memory CD4 T-cell': '0.0', 'Naive CD4 T-cell': '0.1', 'Memory CD8 T-cell': '0.2', 'Naive CD8 T-cell': '0.3', 'Memory B-cell': '0.0', 'Naive B-cell': '0.1', 'Plasmacytoid DC': '46.6', 'Myeloid DC': '8.5', 'NK-cell': '0.1', 'Total PBMC': '0.7', 'Vd2 gdTCR': '0.0', 'Memory CD4 T-cell Th1\\/Th17': '0.1', 'Memory CD4 T-cell Th17': '0.2', 'Memory CD4 T-cell Th2': '2.9', 'Non-Vd2 gdTCR': '0.1', 'Memory CD4 T-cell Th1': '0.3', 'Memory CD4 T-cell TFH': '0.5', 'Terminal effector memory CD4 T-cell': '0.0', 'Central memory CD8 T-cell': '4.8', 'Effector memory CD8 T-cell': '0.0', 'Terminal effector memory CD8 T-cell': '0.6', 'Non-switched memory B-cell': '0.0', 'Plasmablast': '3.3', 'Switched memory B-cell': '0.0', 'Exhausted memory B-cell': '0.7', 'Progenitor cell': '2.3', 'Memory T-reg': '1.3', 'Naive CD4 T-cell activated': '0.3', 'Naive CD8 T-cell activated': '0.6', 'Naive T-reg': '0.1'}
1O6S, 2O72, 2OMT, 2OMU, 2OMV, 2OMX, 2OMY, 2OMZ, 3FF7, 3FF8, 3L6X, 3L6Y, 4ZT1, 4ZTE, 6CXY, 6OLE, 6OLF, 6OLG, 6VEL, 7STZ, 8H62
{'Adipose Tissue': 1.2125261088039867, 'Adrenal Gland': 0.1914223992248062, 'Bladder': 39.2033519047619, 'Blood': 1.340954264800861, 'Blood Vessel': 0.3121561692883895, 'Brain': 0.8550442199091597, 'Breast': 38.54918344226579, 'Cervix Uteri': 23.539115789473684, 'Colon': 43.41292142490372, 'Esophagus': 53.97513367404844, 'Fallopian Tube': 14.900277777777776, 'Heart': 0.119140469221835, 'Kidney': 25.040449438202245, 'Liver': 26.60802654867257, 'Lung': 35.447986366782004, 'Muscle': 0.1378936151930261, 'Nerve': 17.518468982229404, 'Ovary': 3.6515122222222223, 'Pancreas': 56.89676829268293, 'Pituitary': 24.68741660777385, 'Prostate': 61.279967346938776, 'Salivary Gland': 92.01685185185184, 'Skin': 79.77571720232172, 'Small Intestine': 71.7519320855615, 'Spleen': 10.061029045643156, 'Stomach': 58.07813805013927, 'Testis': 0.8144204986149585, 'Thyroid': 135.176797856049, 'Uterus': 1.442593943661972, 'Vagina': 86.52345512820513}
AURKB
MAQKENSYPWPYGRQTAPSGLSTLPQRVLRKEPVTPSALVLMSRSNVQPTAAPGQKVMENSSGTPDILTRHFTIDDFEIGRPLGKGKFGNVYLAREKKSHFIVALKVLFKSQIEKEGVEHQLRREIEIQAHLHHPNILRLYNYFYDRRRIYLILEYAPRGELYKELQKSCTFDEQRTATIMEELADALMYCHGKKVIHRDIKPENLLLGLKGELKIADFGWSVHAPSLRRKTMCGTLDYLPPEMIEGRMHNEKVDLWCIGVLCYELLVGNPPFESASHNETYRRIVKVDLKFPASVPMGAQDLISKLLRHNPSERLPLAQVSAHPWVRANSRRVLPPSALQSVA
Homo sapiens
Nucleus, Chromosome, Chromosome, centromere, Chromosome, centromere, kinetochore, Cytoplasm, cytoskeleton, spindle, Midbody
Tissue enhanced (bone marrow, lymphoid tissue)
{'Ciliated cells': '0.3', 'Basal respiratory cells': '6.1', 'Club cells': '0.9', 'Ionocytes': '1.1', 'Mucus glandular cells': '0.4', 'Serous glandular cells': '4.7', 'Gastric mucus-secreting cells': '6.5', 'Proximal enterocytes': '1.5', 'Paneth cells': '0.3', 'Distal enterocytes': '1.5', 'Intestinal goblet cells': '11.0', 'Exocrine glandular cells': '-0.317', 'Basal prostatic cells': '0.0', 'Prostatic glandular cells': '0.0', 'Breast glandular cells': '0.203', 'Breast myoepithelial cells': '0.234', 'Glandular and luminal cells': '2.0', 'Secretory cells': '0.3', 'Basal keratinocytes': '8.6', 'Suprabasal keratinocytes': '4.8', 'Basal squamous epithelial cells': '1.6', 'Squamous epithelial cells': '11.1', 'Alveolar cells type 1': '-0.225', 'Alveolar cells type 2': '0.255', 'Salivary duct cells': '0.8', 'Ductal cells': '0.446', 'Hepatocytes': '0.198', 'Cholangiocytes': '0.0', 'Proximal tubular cells': '0.094', 'Distal tubular cells': '0.0', 'Collecting duct cells': '0.0', 'Mesothelial cells': '-0.041', 'Sertoli cells': '0.001', 'Granulosa cells': '2.3', 'Enteroendocrine cells': '1.6', 'Pancreatic endocrine cells': '11.9', 'Leydig cells': '0.026', 'Excitatory neurons': '0.0', 'Inhibitory neurons': '0.0', 'Cone photoreceptor cells': '0.0', 'Rod photoreceptor cells': '0.2', 'Bipolar cells': '0.0', 'Horizontal cells': '0.0', 'Astrocytes': '0.0', 'Oligodendrocyte precursor cells': '0.0', 'Oligodendrocytes': '0.1', 'Microglial cells': '0.0', 'Muller glia cells': '0.0', 'Schwann cells': '0.117', 'Spermatogonia': '0.163', 'Spermatocytes': '0.333', 'Early spermatids': '0.234', 'Late spermatids': '0.007', 'Oocytes': '8.1', 'Cytotrophoblasts': '43.9', 'Syncytiotrophoblasts': '11.6', 'Extravillous trophoblasts': '91.8', 'Endothelial cells': '2.1', 'Lymphatic endothelial cells': '0.2', 'Cardiomyocytes': '0.235', 'Skeletal myocytes': '0.002', 'Smooth muscle cells': '2.2', 'Adipocytes': '0.3', 'Melanocytes': '0.474', 'Fibroblasts': '4.6', 'Peritubular cells': '-0.106', 'Endometrial stromal cells': '1.0', 'Ovarian stromal cells': '0.1', 'Undifferentiated cells': '41.4', 'T-cells': '4.1', 'B-cells': '2.8', 'Plasma cells': '25.9', 'Nk-cells': '2.6', 'Granulocytes': '0.3', 'Monocytes': '0.2', 'Macrophages': '4.8', 'Hofbauer cells': '24.0', 'Kupffer cells': '4.2', 'Dendritic cells': '0.0', 'Langerhans cells': '0.202', 'Erythroid cells': '0.097', 'Adipocytes (Subcutaneous)': '-0.200', 'Adipocytes (Visceral)': '-0.086', 'Breast glandular cells (progenitors)': '0.203', 'Adipocytes (Breast)': '-0.163', 'Colon enterocytes': '0.353', 'Colon enteroendocrine cells': '-0.138', 'Enteric glia cells': '-0.227', 'Mitotic cells (Colon)': '0.731', 'Mitotic cells (Heart)': '0.800', 'Podocytes': '-0.268', 'Ascending Loop of Henle cells': '0.250', 'Intercalated cells': '-0.208', 'Cholangiocyte': '0.204', 'NK-cells (Liver)': '-0.010', 'Respiratory ciliated cells': '-0.029', 'Mitotic cells (Lung)': '0.839', 'NK-cells (Lung)': '-0.099', 'B-cells (Lung)': '0.023', 'Alpha cells': '0.174', 'Beta cells': '0.038', 'Prostate glandular cells': '-0.097', 'Prostate basal glandular cells': '0.206', 'Urothelial cells': '0.307', 'Keratinocyte (other)': '0.306', 'Keratinocyte (granular)': '-0.208', 'Hair cortex cells': '0.058', 'Inner root sheath cells': '0.171', 'Outer root sheath cells': '0.210', 'Sebaceous gland cells': '0.035', 'Eccrine sweat gland cells': '-0.083', 'Adipocytes (Skin)': '-0.192', 'Mitotic cells (Skin)': '0.846', 'Parietal cells': '0.183', 'Chief cells': '0.170', 'Gastric mucous cells': '0.613', 'Gastric enteroendocrine cells': '0.255', 'Mitotic cells (Stomach)': '0.926', 'Parafollicular cells': '-0.103', 'Thyroid glandular cells': '-0.168', 'Mitotic cells (Thyroid)': '0.747', 'Adrenal cortex cells': '0.395', 'Adrenal medulla cells': '0.123', 'Mitotic cells (Adrenal gland)': '0.918', 'Minor salivary glandular cells': '0.097', 'Minor salivary gland ductal cells': '-0.326', 'Minor salivary gland basal cells': '0.652', 'Mitotic cells (Minor salivary gland)': '0.917', 'Adipocytes (Minor salivary gland)': '0.181', 'Somatotropes': '-0.294', 'Lactotropes': '-0.246', 'Gonadotropes': '-0.072', 'Corticotropes': '-0.147', 'Thyrotropes': '-0.116', 'Undifferentiated cells (Pituitary gland)': '0.348', 'Mitotic cells (Spleen)': '0.902', 'Platelets': '0.196', 'Erythrocytes': '0.277', 'Hematopoietic stem cells': '0.390', 'B-cells (Spleen)': '-0.085', 'NK-cells (Spleen)': '-0.256', 'Amygdala excitatory': '0.0', 'Cerebellar inhibitory': '0.1', 'Cge interneuron': '0.1', 'Deep-layer corticothalamic and 6b': '0.0', 'Deep-layer intratelencephalic': '0.1', 'Deep-layer near-projecting': '0.0', 'Eccentric medium spiny neuron': '0.1', 'Hippocampal ca1-3': '0.1', 'Hippocampal ca4': '0.0', 'Hippocampal dentate gyrus': '0.0', 'Lamp5-lhx6 and chandelier': '0.1', 'Lower rhombic lip': '0.1', 'Mammillary body': '0.0', 'Medium spiny neuron': '0.0', 'Mge interneuron': '0.1', 'Midbrain-derived inhibitory': '0.0', 'Miscellaneous': '0.0', 'Splatter': '0.1', 'Thalamic excitatory': '0.0', 'Upper rhombic lip': '0.1', 'Upper-layer intratelencephalic': '0.0', 'Astrocyte': '0.1', 'Bergmann glia': '0.0', 'Central nervous system macrophage': '0.4', 'Choroid plexus epithelial cell': '0.0', 'Committed oligodendrocyte precursor': '0.0', 'Ependymal cell': '0.0', 'Oligodendrocyte': '0.1', 'Oligodendrocyte precursor cell': '0.1', 'Endothelial cell': '0.0', 'Pericyte': '0.0', 'Vascular associated smooth muscle cell': '0.0', 'Fibroblast': '0.1', 'Leukocyte': '0.7', 'Basophil': '1.9', 'Eosinophil': '0.7', 'Neutrophil': '3.3', 'Classical monocyte': '1.8', 'Non-classical monocyte': '1.9', 'Intermediate monocyte': '2.4', 'T-reg': '4.7', 'GdT-cell': '0.5', 'MAIT T-cell': '1.4', 'Memory CD4 T-cell': '1.3', 'Naive CD4 T-cell': '0.8', 'Memory CD8 T-cell': '2.1', 'Naive CD8 T-cell': '0.8', 'Memory B-cell': '1.1', 'Naive B-cell': '0.9', 'Plasmacytoid DC': '0.3', 'Myeloid DC': '0.9', 'NK-cell': '1.3', 'Total PBMC': '6.7', 'Vd2 gdTCR': '0.9', 'Memory CD4 T-cell Th1\\/Th17': '1.5', 'Memory CD4 T-cell Th17': '2.0', 'Memory CD4 T-cell Th2': '2.4', 'Non-Vd2 gdTCR': '0.4', 'Memory CD4 T-cell Th1': '2.6', 'Memory CD4 T-cell TFH': '2.3', 'Terminal effector memory CD4 T-cell': '0.7', 'Central memory CD8 T-cell': '1.5', 'Effector memory CD8 T-cell': '6.0', 'Terminal effector memory CD8 T-cell': '1.2', 'Non-switched memory B-cell': '0.9', 'Plasmablast': '49.4', 'Switched memory B-cell': '3.8', 'Exhausted memory B-cell': '7.2', 'Progenitor cell': '1.0', 'Memory T-reg': '5.6', 'Naive CD4 T-cell activated': '0.1', 'Naive CD8 T-cell activated': '0.1', 'Naive T-reg': '1.1'}
4AF3
{'Adipose Tissue': 1.4738776162790697, 'Adrenal Gland': 1.6113024031007752, 'Bladder': 1.5387504761904762, 'Blood': 32.23255343379979, 'Blood Vessel': 1.0121387715355803, 'Brain': 0.1394279114307343, 'Breast': 1.4640847494553375, 'Cervix Uteri': 2.2752526315789474, 'Colon': 5.039736046213094, 'Esophagus': 9.005606948096885, 'Fallopian Tube': 0.6781999999999999, 'Heart': 0.4651034030197444, 'Kidney': 1.0157044943820224, 'Liver': 1.304555442477876, 'Lung': 4.480531903114187, 'Muscle': 0.152341706102117, 'Nerve': 43.200933441033925, 'Ovary': 1.0221724444444444, 'Pancreas': 0.3695434451219512, 'Pituitary': 0.3656560424028268, 'Prostate': 1.416055224489796, 'Salivary Gland': 3.496744135802469, 'Skin': 17.819689662797124, 'Small Intestine': 12.2027256684492, 'Spleen': 16.24776763485477, 'Stomach': 4.78460852367688, 'Testis': 2.3102357340720223, 'Thyroid': 1.0494922817764163, 'Uterus': 0.8543154929577464, 'Vagina': 9.050123076923075}
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[1.0, 1.0, 0.99, 1.0, 1.0, 1.0, 0.95, 0.99, 0.91, 0.97, 0.94, 1.0, 0.94, 1.0, 0.98, 0.98, 0.99, 0.95, 0.97, 0.93, 0.97, 0.88, 0.95, 0.92, 0.89, 0.96, 0.95, 0.75, 0.96, 0.76, 0.95, 0.72, 0.82, 0.49, 0.46, 0.66, 0.21, 0.14, 0.58, 0.5, 0.01, 0.35, 0.64, 0.47, 0.72, 0.88, 0.87, 0.88, 0.89, 0.89, 0.96, 0.95, 0.98, 0.95, 0.96, 1.0, 0.92, 0.98, 0.97, 0.91, 0.97, 0.83, 0.96, 0.89, 0.85, 0.81, 0.87, 0.83, 0.47, 0.34, 0.82, 0.05, 0.46, 0.36, 0.7, 0.22, 0.05, 0.4, 0.48, 0.59, 0.66, 0.72, 0.29, 0.34, 0.9, 0.54, 0.8, 0.24, 0.16, 0.29, 0.22, 0.29, 0.22, 0.04, 0.41, 0.02, 0.44, 0.75, 0.36, 0.57, 0.23, 0.48, 0.0, 0.06, 0.0, 0.21, 0.11, 0.04, 0.35, 0.24, 0.63, 0.43, 0.04, 0.69, 0.89, 0.53, 0.67, 0.17, 0.5, 0.72, 0.41, 0.11, 0.59, 0.51, 0.1, 0.12, 0.63, 0.1, 0.03, 0.29, 0.54, 0.03, 0.51, 0.18, 0.24, 0.03, 0.02, 0.06, 0.12, 0.03, 0.11, 0.07, 0.43, 0.07, 0.74, 0.37, 0.95, 0.79, 0.4, 0.19, 0.03, 0.01, 0.0, 0.07, 0.2, 0.26, 0.12, 0.37, 0.44, 0.27, 0.27, 0.0, 0.32, 0.55, 0.26, 0.04, 0.58, 0.8, 0.48, 0.62, 0.47, 0.1, 0.63, 0.34, 0.48, 0.23, 0.0, 0.0, 0.09, 0.0, 0.02, 0.24, 0.03, 0.01, 0.0, 0.3, 0.0, 0.0, 0.4, 0.26, 0.01, 0.16, 0.67, 0.39, 0.49, 0.05, 0.09, 0.01, 0.07, 0.08, 0.01, 0.14, 0.0, 0.45, 0.11, 0.0, 0.2, 0.0, 0.04, 0.75, 0.75, 0.02, 0.18, 0.0, 0.07, 0.0, 0.13, 0.42, 0.01, 0.15, 0.41, 0.05, 0.04, 0.51, 0.21, 0.66, 0.96, 0.75, 0.65, 0.29, 0.76, 0.55, 0.64, 0.06, 0.51, 0.31, 0.21, 0.18, 0.07, 0.05, 0.02, 0.0, 0.01, 0.05, 0.24, 0.39, 0.58, 0.4, 0.45, 0.02, 0.4, 0.42, 0.23, 0.01, 0.0, 0.03, 0.0, 0.03, 0.02, 0.0, 0.0, 0.0, 0.0, 0.06, 0.08, 0.0, 0.13, 0.28, 0.26, 0.56, 0.18, 0.05, 0.0, 0.53, 0.32, 1.0, 0.48, 0.64, 0.74, 0.34, 0.01, 0.29, 0.44, 0.16, 0.0, 0.29, 0.7, 0.22, 0.24, 0.23, 0.65, 0.3, 0.36, 0.93, 0.77, 0.06, 0.26, 0.8, 0.3, 0.0, 0.27, 0.37, 0.0, 0.0, 0.36, 0.37, 0.0, 0.04, 0.45, 0.33, 0.41, 0.16, 0.71, 0.52, 0.02, 0.12, 0.48, 0.06, 0.53, 0.51, 0.0, 0.26, 0.55, 0.05, 0.7, 0.06, 0.0, 0.75, 0.6, 0.23, 0.16, 0.58, 0.22, 0.68, 0.48, 0.28, 0.59, 0.57, 0.14, 0.63, 0.58, 0.79, 0.85, 0.87]
null
Component of an E-cadherin/ catenin adhesion complex composed of at least E-cadherin/CDH1, beta-catenin/CTNNB1 or gamma-catenin/JUP, and potentially alpha-catenin/CTNNA1. Forms a ternary complex composed of ADAM10, CADH1 and EPHA4,
null
null
KLRG1, SPEF1, DLGAP5, AJAP1, RAPGEF2, RAB8B, PIP5K1C, PKP2, TRPV4, CTNNB1, CAV1, DDR1, TBC1D2, CTNNA1, JUP, CTNND1, PSEN1, LIMA1, CDH1, JUP, ADAM10, CADH1 , EPHA4,
null
null
null
null
Homodimer
null
79.91949
0.474025
78.962151
0.410058
1,950
P12830
Q96GD4-2
null
degron_data
CDH1
MGPWSRSLSALLLLLQVSSWLCQEPEPCHPGFDAESYTFTVPRRHLERGRVLGRVNFEDCTGRQRTAYFSLDTRFKVGTDGVITVKRPLRFHNPQIHFLVYAWDSTYRKFSTKVTLNTVGHHHRPPPHQASVSGIQAELLTFPNSSPGLRRQKRDWVIPPISCPENEKGPFPKNLVQIKSNKDKEGKVFYSITGQGADTPPVGVFIIERETGWLKVTEPLDRERIATYTLFSHAVSSNGNAVEDPMEILITVTDQNDNKPEFTQEVFKGSVMEGALPGTSVMEVTATDADDDVNTYNAAIAYTILSQDPELPDKNMFTINRNTGVISVVTTGLDRESFPTYTLVVQAADLQGEGLSTTATAVITVTDTNDNPPIFNPTTYKGQVPENEANVVITTLKVTDADAPNTPAWEAVYTILNDDGGQFVVTTNPVNNDGILKTAKGLDFEAKQQYILHVAVTNVVPFEVSLTTSTATVTVDVLDVNEAPIFVPPEKRVEVSEDFGVGQEITSYTAQEPDTFMEQKITYRIWRDTANWLEINPDTGAISTRAELDREDFEHVKNSTYTALIIATDNGSPVATGTGTLLLILSDVNDNAPIPEPRTIFFCERNPKPQVINIIDADLPPNTSPFTAELTHGASANWTIQYNDPTQESIILKPKMALEVGDYKINLKLMDNQNKDQVTTLEVSVCDCEGAAGVCRKAQPVEAGLQIPAILGILGGILALLILILLLLLFLRRRAVVKEPLLPPEDDTRDNVYYYDEEGGGEEDQDFDLSQLHRGLDARPEVTRNDVAPTLMSVPRYLPRPANPDEIGNFIDENLKAADTDPTAPPYDSLLVFDYEGSGSEAASLSSLNSSESDKDQDYDYLNEWGNRFKKLADMYGGGEDD
Homo sapiens
Cell junction, adherens junction, Cell membrane, Endosome, Golgi apparatus, trans-Golgi network, Cytoplasm, Cell junction, desmosome
Tissue enhanced (parathyroid)
{'Ciliated cells': '119.1', 'Basal respiratory cells': '71.1', 'Club cells': '97.3', 'Ionocytes': '81.0', 'Mucus glandular cells': '155.0', 'Serous glandular cells': '67.8', 'Gastric mucus-secreting cells': '133.2', 'Proximal enterocytes': '140.9', 'Paneth cells': '125.1', 'Distal enterocytes': '307.5', 'Intestinal goblet cells': '173.5', 'Exocrine glandular cells': '-0.605', 'Basal prostatic cells': '68.3', 'Prostatic glandular cells': '186.7', 'Breast glandular cells': '0.773', 'Breast myoepithelial cells': '0.700', 'Glandular and luminal cells': '313.0', 'Secretory cells': '82.3', 'Basal keratinocytes': '102.5', 'Suprabasal keratinocytes': '162.6', 'Basal squamous epithelial cells': '51.0', 'Squamous epithelial cells': '106.9', 'Alveolar cells type 1': '0.437', 'Alveolar cells type 2': '0.706', 'Salivary duct cells': '95.9', 'Ductal cells': '0.541', 'Hepatocytes': '0.600', 'Cholangiocytes': '129.7', 'Proximal tubular cells': '0.042', 'Distal tubular cells': '0.0', 'Collecting duct cells': '143.9', 'Mesothelial cells': '0.799', 'Sertoli cells': '0.252', 'Granulosa cells': '12.9', 'Enteroendocrine cells': '92.4', 'Pancreatic endocrine cells': '78.1', 'Leydig cells': '0.264', 'Excitatory neurons': '0.7', 'Inhibitory neurons': '1.3', 'Cone photoreceptor cells': '0.0', 'Rod photoreceptor cells': '0.0', 'Bipolar cells': '0.2', 'Horizontal cells': '0.6', 'Astrocytes': '0.6', 'Oligodendrocyte precursor cells': '0.5', 'Oligodendrocytes': '29.9', 'Microglial cells': '0.9', 'Muller glia cells': '0.1', 'Schwann cells': '0.131', 'Spermatogonia': '0.392', 'Spermatocytes': '0.193', 'Early spermatids': '-0.217', 'Late spermatids': '-0.290', 'Oocytes': '16.9', 'Cytotrophoblasts': '119.2', 'Syncytiotrophoblasts': '45.0', 'Extravillous trophoblasts': '24.9', 'Endothelial cells': '6.1', 'Lymphatic endothelial cells': '0.4', 'Cardiomyocytes': '0.135', 'Skeletal myocytes': '0.107', 'Smooth muscle cells': '5.8', 'Adipocytes': '2.1', 'Melanocytes': '0.335', 'Fibroblasts': '6.5', 'Peritubular cells': '0.210', 'Endometrial stromal cells': '27.7', 'Ovarian stromal cells': '0.7', 'Undifferentiated cells': '101.6', 'T-cells': '2.9', 'B-cells': '4.4', 'Plasma cells': '6.1', 'Nk-cells': '0.0', 'Granulocytes': '8.4', 'Monocytes': '0.0', 'Macrophages': '6.0', 'Hofbauer cells': '4.3', 'Kupffer cells': '1.0', 'Dendritic cells': '5.9', 'Langerhans cells': '0.304', 'Erythroid cells': '0.036', 'Adipocytes (Subcutaneous)': '-0.081', 'Adipocytes (Visceral)': '-0.209', 'Breast glandular cells (progenitors)': '0.538', 'Adipocytes (Breast)': '-0.689', 'Colon enterocytes': '0.790', 'Colon enteroendocrine cells': '0.112', 'Enteric glia cells': '-0.048', 'Mitotic cells (Colon)': '0.299', 'Mitotic cells (Heart)': '0.120', 'Podocytes': '-0.118', 'Ascending Loop of Henle cells': '0.475', 'Intercalated cells': '0.212', 'Cholangiocyte': '0.090', 'NK-cells (Liver)': '-0.005', 'Respiratory ciliated cells': '-0.012', 'Mitotic cells (Lung)': '0.071', 'NK-cells (Lung)': '-0.266', 'B-cells (Lung)': '-0.296', 'Alpha cells': '0.270', 'Beta cells': '0.152', 'Prostate glandular cells': '0.764', 'Prostate basal glandular cells': '0.540', 'Urothelial cells': '0.205', 'Keratinocyte (other)': '0.510', 'Keratinocyte (granular)': '0.055', 'Hair cortex cells': '0.080', 'Inner root sheath cells': '0.131', 'Outer root sheath cells': '0.175', 'Sebaceous gland cells': '0.156', 'Eccrine sweat gland cells': '-0.207', 'Adipocytes (Skin)': '-0.244', 'Mitotic cells (Skin)': '0.442', 'Parietal cells': '0.654', 'Chief cells': '0.649', 'Gastric mucous cells': '0.781', 'Gastric enteroendocrine cells': '0.590', 'Mitotic cells (Stomach)': '0.445', 'Parafollicular cells': '0.173', 'Thyroid glandular cells': '0.865', 'Mitotic cells (Thyroid)': '-0.081', 'Adrenal cortex cells': '0.051', 'Adrenal medulla cells': '0.087', 'Mitotic cells (Adrenal gland)': '0.072', 'Minor salivary glandular cells': '0.371', 'Minor salivary gland ductal cells': '-0.142', 'Minor salivary gland basal cells': '0.582', 'Mitotic cells (Minor salivary gland)': '0.567', 'Adipocytes (Minor salivary gland)': '0.050', 'Somatotropes': '0.121', 'Lactotropes': '0.322', 'Gonadotropes': '0.330', 'Corticotropes': '0.180', 'Thyrotropes': '0.496', 'Undifferentiated cells (Pituitary gland)': '-0.108', 'Mitotic cells (Spleen)': '-0.228', 'Platelets': '-0.050', 'Erythrocytes': '-0.158', 'Hematopoietic stem cells': '-0.211', 'B-cells (Spleen)': '0.266', 'NK-cells (Spleen)': '0.309', 'Amygdala excitatory': '1.0', 'Cerebellar inhibitory': '0.9', 'Cge interneuron': '0.7', 'Deep-layer corticothalamic and 6b': '1.5', 'Deep-layer intratelencephalic': '0.7', 'Deep-layer near-projecting': '0.7', 'Eccentric medium spiny neuron': '0.6', 'Hippocampal ca1-3': '1.9', 'Hippocampal ca4': '1.2', 'Hippocampal dentate gyrus': '1.1', 'Lamp5-lhx6 and chandelier': '0.5', 'Lower rhombic lip': '0.8', 'Mammillary body': '0.6', 'Medium spiny neuron': '0.7', 'Mge interneuron': '1.7', 'Midbrain-derived inhibitory': '0.7', 'Miscellaneous': '0.9', 'Splatter': '3.8', 'Thalamic excitatory': '0.5', 'Upper rhombic lip': '0.8', 'Upper-layer intratelencephalic': '0.6', 'Astrocyte': '4.4', 'Bergmann glia': '0.2', 'Central nervous system macrophage': '0.6', 'Choroid plexus epithelial cell': '52.1', 'Committed oligodendrocyte precursor': '41.5', 'Ependymal cell': '4.8', 'Oligodendrocyte': '53.1', 'Oligodendrocyte precursor cell': '2.4', 'Endothelial cell': '0.7', 'Pericyte': '0.3', 'Vascular associated smooth muscle cell': '0.0', 'Fibroblast': '17.4', 'Leukocyte': '1.1', 'Basophil': '0.0', 'Eosinophil': '0.0', 'Neutrophil': '0.0', 'Classical monocyte': '0.0', 'Non-classical monocyte': '0.0', 'Intermediate monocyte': '0.0', 'T-reg': '2.3', 'GdT-cell': '0.0', 'MAIT T-cell': '0.0', 'Memory CD4 T-cell': '0.0', 'Naive CD4 T-cell': '0.1', 'Memory CD8 T-cell': '0.2', 'Naive CD8 T-cell': '0.3', 'Memory B-cell': '0.0', 'Naive B-cell': '0.1', 'Plasmacytoid DC': '46.6', 'Myeloid DC': '8.5', 'NK-cell': '0.1', 'Total PBMC': '0.7', 'Vd2 gdTCR': '0.0', 'Memory CD4 T-cell Th1\\/Th17': '0.1', 'Memory CD4 T-cell Th17': '0.2', 'Memory CD4 T-cell Th2': '2.9', 'Non-Vd2 gdTCR': '0.1', 'Memory CD4 T-cell Th1': '0.3', 'Memory CD4 T-cell TFH': '0.5', 'Terminal effector memory CD4 T-cell': '0.0', 'Central memory CD8 T-cell': '4.8', 'Effector memory CD8 T-cell': '0.0', 'Terminal effector memory CD8 T-cell': '0.6', 'Non-switched memory B-cell': '0.0', 'Plasmablast': '3.3', 'Switched memory B-cell': '0.0', 'Exhausted memory B-cell': '0.7', 'Progenitor cell': '2.3', 'Memory T-reg': '1.3', 'Naive CD4 T-cell activated': '0.3', 'Naive CD8 T-cell activated': '0.6', 'Naive T-reg': '0.1'}
1O6S, 2O72, 2OMT, 2OMU, 2OMV, 2OMX, 2OMY, 2OMZ, 3FF7, 3FF8, 3L6X, 3L6Y, 4ZT1, 4ZTE, 6CXY, 6OLE, 6OLF, 6OLG, 6VEL, 7STZ, 8H62
{'Adipose Tissue': 1.2125261088039867, 'Adrenal Gland': 0.1914223992248062, 'Bladder': 39.2033519047619, 'Blood': 1.340954264800861, 'Blood Vessel': 0.3121561692883895, 'Brain': 0.8550442199091597, 'Breast': 38.54918344226579, 'Cervix Uteri': 23.539115789473684, 'Colon': 43.41292142490372, 'Esophagus': 53.97513367404844, 'Fallopian Tube': 14.900277777777776, 'Heart': 0.119140469221835, 'Kidney': 25.040449438202245, 'Liver': 26.60802654867257, 'Lung': 35.447986366782004, 'Muscle': 0.1378936151930261, 'Nerve': 17.518468982229404, 'Ovary': 3.6515122222222223, 'Pancreas': 56.89676829268293, 'Pituitary': 24.68741660777385, 'Prostate': 61.279967346938776, 'Salivary Gland': 92.01685185185184, 'Skin': 79.77571720232172, 'Small Intestine': 71.7519320855615, 'Spleen': 10.061029045643156, 'Stomach': 58.07813805013927, 'Testis': 0.8144204986149585, 'Thyroid': 135.176797856049, 'Uterus': 1.442593943661972, 'Vagina': 86.52345512820513}
AURKB
MAQKENSYPWPYGRQTAPSGLSTLPQRVLRKEPVTPSALVLMSRSNVQPTAAPGQKVMENSSGTPDILTRHFTIDDFEIGRPLGKALLCLWPEASSVSSPSHPNILRLYNYFYDRRRIYLILEYAPRGELYKELQKSCTFDEQRTATIMEELADALMYCHGKKVIHRDIKPENLLLGLKGELKIADFGWSVHAPSLRRKTMCGTLDYLPPEMIEGRMHNEKVDLWCIGVLCYELLVGNPPFESASHNETYRRIVKVDLKFPASVPMGAQDLISKLLRHNPSERLPLAQVSAHPWVRANSRRVLPPSALQSVA
Homo sapiens
null
Not found
{}
null
{'Adipose Tissue': 1.4738776162790697, 'Adrenal Gland': 1.6113024031007752, 'Bladder': 1.5387504761904762, 'Blood': 32.23255343379979, 'Blood Vessel': 1.0121387715355803, 'Brain': 0.1394279114307343, 'Breast': 1.4640847494553375, 'Cervix Uteri': 2.2752526315789474, 'Colon': 5.039736046213094, 'Esophagus': 9.005606948096885, 'Fallopian Tube': 0.6781999999999999, 'Heart': 0.4651034030197444, 'Kidney': 1.0157044943820224, 'Liver': 1.304555442477876, 'Lung': 4.480531903114187, 'Muscle': 0.152341706102117, 'Nerve': 43.200933441033925, 'Ovary': 1.0221724444444444, 'Pancreas': 0.3695434451219512, 'Pituitary': 0.3656560424028268, 'Prostate': 1.416055224489796, 'Salivary Gland': 3.496744135802469, 'Skin': 17.819689662797124, 'Small Intestine': 12.2027256684492, 'Spleen': 16.24776763485477, 'Stomach': 4.78460852367688, 'Testis': 2.3102357340720223, 'Thyroid': 1.0494922817764163, 'Uterus': 0.8543154929577464, 'Vagina': 9.050123076923075}
[39.93, 46.46, 52.9, 44.21, 41.4, 39.93, 35.91, 38.61, 36.44, 36.25, 34.86, 32.82, 32.01, 32.75, 31.69, 35.64, 36.35, 34.66, 33.32, 32.71, 35.01, 30.17, 37.05, 36.53, 48.19, 58.22, 64.94, 73.22, 78.33, 82.63, 85.79, 89.39, 87.89, 85.58, 83.93, 89.1, 89.27, 90.66, 87.86, 86.2, 82.97, 72.75, 73.3, 76.44, 82.38, 82.41, 79.49, 86.6, 76.32, 85.48, 88.69, 84.35, 87.75, 90.57, 88.72, 89.46, 87.48, 85.3, 81.72, 79.46, 77.26, 69.01, 67.1, 62.83, 67.71, 74.96, 82.95, 86.74, 86.35, 86.49, 84.6, 85.99, 85.64, 87.19, 89.23, 89.3, 90.62, 84.21, 85.42, 83.34, 84.28, 89.8, 89.78, 87.53, 87.64, 85.98, 81.31, 80.85, 78.74, 80.15, 70.67, 69.91, 72.91, 77.13, 83.26, 84.67, 90.36, 89.7, 92.74, 89.99, 92.55, 88.84, 87.15, 83.78, 78.78, 81.48, 78.75, 84.94, 88.04, 89.37, 92.07, 91.77, 92.31, 91.07, 90.65, 87.61, 83.41, 78.8, 63.24, 54.89, 47.42, 40.03, 40.26, 30.18, 41.24, 38.09, 36.95, 39.02, 37.83, 36.36, 36.19, 34.8, 36.01, 35.89, 38.28, 40.63, 35.0, 43.8, 39.75, 41.2, 46.04, 45.19, 52.52, 50.11, 47.93, 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null
null
null
Component of an E-cadherin/ catenin adhesion complex composed of at least E-cadherin/CDH1, beta-catenin/CTNNB1 or gamma-catenin/JUP, and potentially alpha-catenin/CTNNA1. Forms a ternary complex composed of ADAM10, CADH1 and EPHA4,
null
null
KLRG1, SPEF1, DLGAP5, AJAP1, RAPGEF2, RAB8B, PIP5K1C, PKP2, TRPV4, CTNNB1, CAV1, DDR1, TBC1D2, CTNNA1, JUP, CTNND1, PSEN1, LIMA1, CDH1, JUP, ADAM10, CADH1 , EPHA4,
null
null
null
null
Homodimer
null
79.91949
0.474025
null
null
1,950
P12830
Q96GD4-5
null
degron_data
CDH1
MGPWSRSLSALLLLLQVSSWLCQEPEPCHPGFDAESYTFTVPRRHLERGRVLGRVNFEDCTGRQRTAYFSLDTRFKVGTDGVITVKRPLRFHNPQIHFLVYAWDSTYRKFSTKVTLNTVGHHHRPPPHQASVSGIQAELLTFPNSSPGLRRQKRDWVIPPISCPENEKGPFPKNLVQIKSNKDKEGKVFYSITGQGADTPPVGVFIIERETGWLKVTEPLDRERIATYTLFSHAVSSNGNAVEDPMEILITVTDQNDNKPEFTQEVFKGSVMEGALPGTSVMEVTATDADDDVNTYNAAIAYTILSQDPELPDKNMFTINRNTGVISVVTTGLDRESFPTYTLVVQAADLQGEGLSTTATAVITVTDTNDNPPIFNPTTYKGQVPENEANVVITTLKVTDADAPNTPAWEAVYTILNDDGGQFVVTTNPVNNDGILKTAKGLDFEAKQQYILHVAVTNVVPFEVSLTTSTATVTVDVLDVNEAPIFVPPEKRVEVSEDFGVGQEITSYTAQEPDTFMEQKITYRIWRDTANWLEINPDTGAISTRAELDREDFEHVKNSTYTALIIATDNGSPVATGTGTLLLILSDVNDNAPIPEPRTIFFCERNPKPQVINIIDADLPPNTSPFTAELTHGASANWTIQYNDPTQESIILKPKMALEVGDYKINLKLMDNQNKDQVTTLEVSVCDCEGAAGVCRKAQPVEAGLQIPAILGILGGILALLILILLLLLFLRRRAVVKEPLLPPEDDTRDNVYYYDEEGGGEEDQDFDLSQLHRGLDARPEVTRNDVAPTLMSVPRYLPRPANPDEIGNFIDENLKAADTDPTAPPYDSLLVFDYEGSGSEAASLSSLNSSESDKDQDYDYLNEWGNRFKKLADMYGGGEDD
Homo sapiens
Cell junction, adherens junction, Cell membrane, Endosome, Golgi apparatus, trans-Golgi network, Cytoplasm, Cell junction, desmosome
Tissue enhanced (parathyroid)
{'Ciliated cells': '119.1', 'Basal respiratory cells': '71.1', 'Club cells': '97.3', 'Ionocytes': '81.0', 'Mucus glandular cells': '155.0', 'Serous glandular cells': '67.8', 'Gastric mucus-secreting cells': '133.2', 'Proximal enterocytes': '140.9', 'Paneth cells': '125.1', 'Distal enterocytes': '307.5', 'Intestinal goblet cells': '173.5', 'Exocrine glandular cells': '-0.605', 'Basal prostatic cells': '68.3', 'Prostatic glandular cells': '186.7', 'Breast glandular cells': '0.773', 'Breast myoepithelial cells': '0.700', 'Glandular and luminal cells': '313.0', 'Secretory cells': '82.3', 'Basal keratinocytes': '102.5', 'Suprabasal keratinocytes': '162.6', 'Basal squamous epithelial cells': '51.0', 'Squamous epithelial cells': '106.9', 'Alveolar cells type 1': '0.437', 'Alveolar cells type 2': '0.706', 'Salivary duct cells': '95.9', 'Ductal cells': '0.541', 'Hepatocytes': '0.600', 'Cholangiocytes': '129.7', 'Proximal tubular cells': '0.042', 'Distal tubular cells': '0.0', 'Collecting duct cells': '143.9', 'Mesothelial cells': '0.799', 'Sertoli cells': '0.252', 'Granulosa cells': '12.9', 'Enteroendocrine cells': '92.4', 'Pancreatic endocrine cells': '78.1', 'Leydig cells': '0.264', 'Excitatory neurons': '0.7', 'Inhibitory neurons': '1.3', 'Cone photoreceptor cells': '0.0', 'Rod photoreceptor cells': '0.0', 'Bipolar cells': '0.2', 'Horizontal cells': '0.6', 'Astrocytes': '0.6', 'Oligodendrocyte precursor cells': '0.5', 'Oligodendrocytes': '29.9', 'Microglial cells': '0.9', 'Muller glia cells': '0.1', 'Schwann cells': '0.131', 'Spermatogonia': '0.392', 'Spermatocytes': '0.193', 'Early spermatids': '-0.217', 'Late spermatids': '-0.290', 'Oocytes': '16.9', 'Cytotrophoblasts': '119.2', 'Syncytiotrophoblasts': '45.0', 'Extravillous trophoblasts': '24.9', 'Endothelial cells': '6.1', 'Lymphatic endothelial cells': '0.4', 'Cardiomyocytes': '0.135', 'Skeletal myocytes': '0.107', 'Smooth muscle cells': '5.8', 'Adipocytes': '2.1', 'Melanocytes': '0.335', 'Fibroblasts': '6.5', 'Peritubular cells': '0.210', 'Endometrial stromal cells': '27.7', 'Ovarian stromal cells': '0.7', 'Undifferentiated cells': '101.6', 'T-cells': '2.9', 'B-cells': '4.4', 'Plasma cells': '6.1', 'Nk-cells': '0.0', 'Granulocytes': '8.4', 'Monocytes': '0.0', 'Macrophages': '6.0', 'Hofbauer cells': '4.3', 'Kupffer cells': '1.0', 'Dendritic cells': '5.9', 'Langerhans cells': '0.304', 'Erythroid cells': '0.036', 'Adipocytes (Subcutaneous)': '-0.081', 'Adipocytes (Visceral)': '-0.209', 'Breast glandular cells (progenitors)': '0.538', 'Adipocytes (Breast)': '-0.689', 'Colon enterocytes': '0.790', 'Colon enteroendocrine cells': '0.112', 'Enteric glia cells': '-0.048', 'Mitotic cells (Colon)': '0.299', 'Mitotic cells (Heart)': '0.120', 'Podocytes': '-0.118', 'Ascending Loop of Henle cells': '0.475', 'Intercalated cells': '0.212', 'Cholangiocyte': '0.090', 'NK-cells (Liver)': '-0.005', 'Respiratory ciliated cells': '-0.012', 'Mitotic cells (Lung)': '0.071', 'NK-cells (Lung)': '-0.266', 'B-cells (Lung)': '-0.296', 'Alpha cells': '0.270', 'Beta cells': '0.152', 'Prostate glandular cells': '0.764', 'Prostate basal glandular cells': '0.540', 'Urothelial cells': '0.205', 'Keratinocyte (other)': '0.510', 'Keratinocyte (granular)': '0.055', 'Hair cortex cells': '0.080', 'Inner root sheath cells': '0.131', 'Outer root sheath cells': '0.175', 'Sebaceous gland cells': '0.156', 'Eccrine sweat gland cells': '-0.207', 'Adipocytes (Skin)': '-0.244', 'Mitotic cells (Skin)': '0.442', 'Parietal cells': '0.654', 'Chief cells': '0.649', 'Gastric mucous cells': '0.781', 'Gastric enteroendocrine cells': '0.590', 'Mitotic cells (Stomach)': '0.445', 'Parafollicular cells': '0.173', 'Thyroid glandular cells': '0.865', 'Mitotic cells (Thyroid)': '-0.081', 'Adrenal cortex cells': '0.051', 'Adrenal medulla cells': '0.087', 'Mitotic cells (Adrenal gland)': '0.072', 'Minor salivary glandular cells': '0.371', 'Minor salivary gland ductal cells': '-0.142', 'Minor salivary gland basal cells': '0.582', 'Mitotic cells (Minor salivary gland)': '0.567', 'Adipocytes (Minor salivary gland)': '0.050', 'Somatotropes': '0.121', 'Lactotropes': '0.322', 'Gonadotropes': '0.330', 'Corticotropes': '0.180', 'Thyrotropes': '0.496', 'Undifferentiated cells (Pituitary gland)': '-0.108', 'Mitotic cells (Spleen)': '-0.228', 'Platelets': '-0.050', 'Erythrocytes': '-0.158', 'Hematopoietic stem cells': '-0.211', 'B-cells (Spleen)': '0.266', 'NK-cells (Spleen)': '0.309', 'Amygdala excitatory': '1.0', 'Cerebellar inhibitory': '0.9', 'Cge interneuron': '0.7', 'Deep-layer corticothalamic and 6b': '1.5', 'Deep-layer intratelencephalic': '0.7', 'Deep-layer near-projecting': '0.7', 'Eccentric medium spiny neuron': '0.6', 'Hippocampal ca1-3': '1.9', 'Hippocampal ca4': '1.2', 'Hippocampal dentate gyrus': '1.1', 'Lamp5-lhx6 and chandelier': '0.5', 'Lower rhombic lip': '0.8', 'Mammillary body': '0.6', 'Medium spiny neuron': '0.7', 'Mge interneuron': '1.7', 'Midbrain-derived inhibitory': '0.7', 'Miscellaneous': '0.9', 'Splatter': '3.8', 'Thalamic excitatory': '0.5', 'Upper rhombic lip': '0.8', 'Upper-layer intratelencephalic': '0.6', 'Astrocyte': '4.4', 'Bergmann glia': '0.2', 'Central nervous system macrophage': '0.6', 'Choroid plexus epithelial cell': '52.1', 'Committed oligodendrocyte precursor': '41.5', 'Ependymal cell': '4.8', 'Oligodendrocyte': '53.1', 'Oligodendrocyte precursor cell': '2.4', 'Endothelial cell': '0.7', 'Pericyte': '0.3', 'Vascular associated smooth muscle cell': '0.0', 'Fibroblast': '17.4', 'Leukocyte': '1.1', 'Basophil': '0.0', 'Eosinophil': '0.0', 'Neutrophil': '0.0', 'Classical monocyte': '0.0', 'Non-classical monocyte': '0.0', 'Intermediate monocyte': '0.0', 'T-reg': '2.3', 'GdT-cell': '0.0', 'MAIT T-cell': '0.0', 'Memory CD4 T-cell': '0.0', 'Naive CD4 T-cell': '0.1', 'Memory CD8 T-cell': '0.2', 'Naive CD8 T-cell': '0.3', 'Memory B-cell': '0.0', 'Naive B-cell': '0.1', 'Plasmacytoid DC': '46.6', 'Myeloid DC': '8.5', 'NK-cell': '0.1', 'Total PBMC': '0.7', 'Vd2 gdTCR': '0.0', 'Memory CD4 T-cell Th1\\/Th17': '0.1', 'Memory CD4 T-cell Th17': '0.2', 'Memory CD4 T-cell Th2': '2.9', 'Non-Vd2 gdTCR': '0.1', 'Memory CD4 T-cell Th1': '0.3', 'Memory CD4 T-cell TFH': '0.5', 'Terminal effector memory CD4 T-cell': '0.0', 'Central memory CD8 T-cell': '4.8', 'Effector memory CD8 T-cell': '0.0', 'Terminal effector memory CD8 T-cell': '0.6', 'Non-switched memory B-cell': '0.0', 'Plasmablast': '3.3', 'Switched memory B-cell': '0.0', 'Exhausted memory B-cell': '0.7', 'Progenitor cell': '2.3', 'Memory T-reg': '1.3', 'Naive CD4 T-cell activated': '0.3', 'Naive CD8 T-cell activated': '0.6', 'Naive T-reg': '0.1'}
1O6S, 2O72, 2OMT, 2OMU, 2OMV, 2OMX, 2OMY, 2OMZ, 3FF7, 3FF8, 3L6X, 3L6Y, 4ZT1, 4ZTE, 6CXY, 6OLE, 6OLF, 6OLG, 6VEL, 7STZ, 8H62
{'Adipose Tissue': 1.2125261088039867, 'Adrenal Gland': 0.1914223992248062, 'Bladder': 39.2033519047619, 'Blood': 1.340954264800861, 'Blood Vessel': 0.3121561692883895, 'Brain': 0.8550442199091597, 'Breast': 38.54918344226579, 'Cervix Uteri': 23.539115789473684, 'Colon': 43.41292142490372, 'Esophagus': 53.97513367404844, 'Fallopian Tube': 14.900277777777776, 'Heart': 0.119140469221835, 'Kidney': 25.040449438202245, 'Liver': 26.60802654867257, 'Lung': 35.447986366782004, 'Muscle': 0.1378936151930261, 'Nerve': 17.518468982229404, 'Ovary': 3.6515122222222223, 'Pancreas': 56.89676829268293, 'Pituitary': 24.68741660777385, 'Prostate': 61.279967346938776, 'Salivary Gland': 92.01685185185184, 'Skin': 79.77571720232172, 'Small Intestine': 71.7519320855615, 'Spleen': 10.061029045643156, 'Stomach': 58.07813805013927, 'Testis': 0.8144204986149585, 'Thyroid': 135.176797856049, 'Uterus': 1.442593943661972, 'Vagina': 86.52345512820513}
AURKB
MAQKENSYPWPYGRQTAPSGLSTLPQRVLRKEPVTPSALVLMSRSNVQPTAAPGQKVMENSSGTPDILTRRHFTIDDFEIGRPLGKGKFGNVYLAREKKSHFIVALKVLFKSQIEKEGVEHQLRREIEIQAHLHHPNILRLYNYFYDRRRIYLILEYAPRGELYKELQKSCTFDEQRTATIMEELADALMYCHGKKVIHRDIKPENLLLGLKGELKIADFGWSVHAPSLRRKTMCGTLDYLPPEMIEGRMHNEKVDLWCIGVLCYELLVGNPPFESASHNETYRRIVKVDLKFPASVPMGAQDLISKLLRHNPSERLPLAQVSAHPWVRANSRRVLPPSALQSVA
Homo sapiens
null
Not found
{}
null
{'Adipose Tissue': 1.4738776162790697, 'Adrenal Gland': 1.6113024031007752, 'Bladder': 1.5387504761904762, 'Blood': 32.23255343379979, 'Blood Vessel': 1.0121387715355803, 'Brain': 0.1394279114307343, 'Breast': 1.4640847494553375, 'Cervix Uteri': 2.2752526315789474, 'Colon': 5.039736046213094, 'Esophagus': 9.005606948096885, 'Fallopian Tube': 0.6781999999999999, 'Heart': 0.4651034030197444, 'Kidney': 1.0157044943820224, 'Liver': 1.304555442477876, 'Lung': 4.480531903114187, 'Muscle': 0.152341706102117, 'Nerve': 43.200933441033925, 'Ovary': 1.0221724444444444, 'Pancreas': 0.3695434451219512, 'Pituitary': 0.3656560424028268, 'Prostate': 1.416055224489796, 'Salivary Gland': 3.496744135802469, 'Skin': 17.819689662797124, 'Small Intestine': 12.2027256684492, 'Spleen': 16.24776763485477, 'Stomach': 4.78460852367688, 'Testis': 2.3102357340720223, 'Thyroid': 1.0494922817764163, 'Uterus': 0.8543154929577464, 'Vagina': 9.050123076923075}
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73.27, 70.36, 72.63, 72.69, 68.11, 66.06, 60.67, 52.64, 44.07, 48.46, 43.79, 36.31]
[1.0, 1.0, 1.0, 1.0, 0.98, 1.0, 0.91, 0.96, 0.9, 0.88, 1.0, 1.0, 1.0, 1.0, 1.0, 0.87, 0.99, 0.76, 0.96, 1.0, 0.98, 0.95, 0.93, 0.92, 0.87, 0.92, 0.69, 0.71, 0.79, 0.3, 0.2, 0.17, 0.63, 0.32, 0.89, 0.66, 0.1, 0.62, 0.15, 0.67, 0.03, 0.67, 0.77, 0.54, 0.57, 0.04, 0.68, 0.73, 0.54, 0.54, 0.59, 0.08, 0.19, 0.61, 0.0, 0.39, 0.06, 0.63, 0.14, 0.63, 0.49, 0.83, 0.72, 0.93, 0.78, 0.07, 0.63, 0.12, 0.52, 0.15, 0.6, 0.19, 0.51, 0.41, 0.03, 0.62, 0.11, 0.3, 0.46, 0.47, 0.0, 0.23, 0.0, 0.24, 0.03, 0.5, 0.67, 0.61, 0.06, 0.78, 0.04, 0.83, 0.7, 0.57, 0.54, 0.13, 0.52, 0.06, 0.45, 0.0, 0.11, 0.0, 0.38, 0.12, 0.54, 0.79, 0.81, 0.65, 0.6, 0.24, 0.6, 0.01, 0.47, 0.01, 0.12, 0.0, 0.25, 0.26, 0.46, 0.93, 0.85, 0.99, 0.94, 1.0, 0.91, 0.99, 0.99, 0.98, 1.0, 1.0, 1.0, 1.0, 0.99, 0.98, 0.98, 0.92, 0.93, 0.87, 0.82, 0.85, 0.76, 0.9, 0.91, 0.9, 0.93, 0.65, 0.96, 0.84, 0.86, 0.96, 0.99, 0.96, 0.7, 0.92, 0.89, 0.8, 0.83, 0.23, 0.86, 0.73, 0.12, 0.62, 0.06, 0.4, 0.02, 0.42, 0.35, 0.9, 0.64, 0.82, 0.29, 0.51, 0.17, 0.54, 0.27, 0.29, 0.51, 0.08, 0.77, 0.06, 0.62, 0.39, 0.34, 0.94, 0.83, 0.46, 0.51, 0.07, 0.17, 0.07, 0.41, 0.14, 0.31, 0.2, 0.36, 0.0, 0.13, 0.59, 0.53, 0.77, 0.2, 0.64, 0.35, 0.0, 0.02, 0.39, 0.18, 0.39, 0.57, 0.63, 0.39, 0.0, 0.32, 0.0, 0.18, 0.03, 0.29, 0.47, 0.55, 0.03, 0.34, 0.2, 0.45, 0.56, 0.17, 0.37, 0.59, 0.01, 0.39, 0.0, 0.39, 0.05, 0.28, 0.07, 0.29, 0.26, 0.64, 0.82, 0.64, 0.63, 0.76, 0.15, 0.39, 0.95, 0.57, 0.28, 0.58, 0.02, 0.43, 0.0, 0.29, 0.09, 0.4, 0.13, 0.49, 0.31, 0.53, 0.32, 0.66, 0.01, 0.71, 0.13, 0.56, 0.54, 0.84, 0.51, 0.06, 0.82, 0.14, 0.54, 0.07, 0.63, 0.05, 0.7, 0.17, 0.75, 0.51, 0.64, 0.36, 0.67, 0.15, 0.12, 0.61, 0.0, 0.33, 0.14, 0.62, 0.2, 0.52, 0.05, 0.14, 0.63, 0.95, 0.85, 0.32, 0.6, 0.1, 0.12, 0.17, 0.17, 0.06, 0.08, 0.41, 0.28, 0.55, 0.49, 0.09, 0.68, 0.23, 0.53, 0.64, 0.52, 0.42, 0.64, 0.64, 0.0, 0.08, 0.44, 0.13, 0.48, 0.52, 0.81, 0.44, 0.0, 0.26, 0.0, 0.21, 0.03, 0.46, 0.27, 0.71, 0.45, 0.06, 0.28, 0.28, 0.4, 0.65, 0.28, 0.46, 0.61, 0.0, 0.36, 0.0, 0.32, 0.01, 0.22, 0.0, 0.05, 0.0, 0.41, 0.46, 0.42, 0.82, 0.48, 0.4, 0.5, 0.17, 0.62, 0.06, 0.32, 0.0, 0.25, 0.0, 0.42, 0.08, 0.41, 0.27, 0.16, 0.04, 0.36, 0.32, 0.2, 0.0, 0.52, 0.04, 0.66, 0.47, 0.52, 0.78, 0.09, 0.77, 0.08, 0.6, 0.0, 0.31, 0.03, 0.58, 0.47, 0.59, 0.44, 0.23, 0.54, 0.1, 0.18, 0.45, 0.0, 0.53, 0.11, 0.59, 0.17, 0.51, 0.01, 0.19, 0.71, 0.77, 0.3, 0.44, 0.08, 0.14, 0.52, 0.05, 0.37, 0.1, 0.42, 0.23, 0.61, 0.43, 0.22, 0.96, 0.54, 0.4, 0.3, 0.07, 0.39, 0.17, 0.43, 0.38, 0.3, 0.8, 0.83, 0.44, 0.03, 0.11, 0.0, 0.23, 0.0, 0.31, 0.0, 0.38, 0.58, 0.51, 0.01, 0.49, 0.13, 0.26, 0.69, 0.46, 0.41, 0.51, 0.06, 0.51, 0.03, 0.38, 0.0, 0.06, 0.0, 0.34, 0.08, 0.53, 0.42, 0.88, 0.25, 0.75, 0.49, 1.0, 0.34, 0.86, 0.48, 0.18, 0.52, 0.01, 0.32, 0.0, 0.19, 0.0, 0.3, 0.05, 0.44, 0.27, 0.43, 0.11, 0.31, 0.39, 0.03, 0.55, 0.04, 0.52, 0.51, 0.64, 0.57, 0.19, 0.68, 0.13, 0.84, 0.06, 0.31, 0.07, 0.69, 0.26, 0.37, 0.53, 0.67, 0.5, 0.56, 0.14, 0.18, 0.47, 0.01, 0.47, 0.15, 0.61, 0.28, 0.2, 0.02, 0.76, 0.55, 0.31, 0.94, 0.22, 0.57, 0.17, 0.4, 0.07, 0.5, 0.31, 0.7, 0.2, 0.14, 0.3, 0.23, 0.58, 0.07, 0.06, 0.55, 0.15, 0.46, 0.43, 0.64, 0.53, 0.0, 0.18, 0.01, 0.23, 0.02, 0.63, 0.33, 0.79, 0.06, 0.38, 0.07, 0.14, 0.23, 0.68, 0.89, 0.29, 0.06, 0.72, 0.92, 0.24, 0.25, 0.0, 0.46, 0.02, 0.21, 0.01, 0.06, 0.0, 0.05, 0.07, 0.61, 0.17, 0.89, 0.72, 0.66, 0.14, 0.52, 0.07, 0.58, 0.01, 0.26, 0.0, 0.13, 0.0, 0.29, 0.04, 0.46, 0.27, 0.28, 0.23, 0.56, 0.32, 0.25, 0.0, 0.33, 0.05, 0.55, 0.5, 0.58, 0.53, 0.04, 0.27, 0.02, 0.04, 0.37, 0.67, 0.74, 0.35, 0.62, 0.54, 0.26, 0.46, 0.0, 0.47, 0.09, 0.45, 0.15, 0.39, 0.05, 0.44, 0.85, 0.56, 0.11, 0.11, 0.35, 0.42, 0.03, 0.32, 0.12, 0.49, 0.19, 0.25, 0.8, 0.6, 0.09, 0.49, 0.57, 0.36, 0.04, 0.35, 0.28, 0.52, 0.39, 0.5, 0.28, 0.93, 0.47, 0.3, 0.47, 0.08, 0.02, 0.18, 0.01, 0.34, 0.23, 0.55, 0.57, 0.91, 0.1, 0.78, 0.52, 0.34, 0.61, 0.24, 0.75, 0.0, 0.2, 0.02, 0.24, 0.0, 0.18, 0.04, 0.44, 0.59, 0.71, 0.29, 0.52, 0.37, 0.5, 0.11, 0.6, 0.02, 0.48, 0.01, 0.16, 0.04, 0.35, 0.66, 0.47, 0.74, 0.14, 0.62, 0.16, 0.77, 0.79, 0.27, 0.93, 0.69, 0.88, 0.88, 0.85, 0.87, 0.91, 0.92, 0.82, 0.63, 0.75, 0.7, 0.7, 0.38, 0.43, 0.64, 0.55, 0.54, 0.59, 0.45, 0.47, 0.5, 0.58, 0.52, 0.61, 0.57, 0.52, 0.68, 0.44, 0.6, 0.61, 0.58, 0.55, 0.5, 0.61, 0.61, 0.86, 0.86, 0.75, 0.91, 0.96, 0.93, 1.0, 0.87, 0.97, 0.91, 0.95, 0.86, 0.98, 0.93, 0.88, 0.59, 0.87, 0.7, 0.67, 0.85, 0.89, 0.88, 0.91, 0.93, 0.88, 0.99, 0.92, 1.0, 0.79, 0.9, 1.0, 0.94, 1.0, 0.97, 0.96, 0.9, 0.63, 0.68, 0.48, 0.54, 0.8, 0.7, 0.7, 0.95, 0.87, 0.77, 0.84, 0.79, 0.89, 0.95, 0.8, 0.77, 0.51, 0.87, 0.7, 0.52, 0.84, 0.91, 0.51, 0.96, 0.79, 0.92, 0.84, 0.21, 0.89, 0.53, 0.52, 0.89, 0.86, 0.26, 0.91, 0.45, 0.68, 0.84, 0.48, 0.44, 0.51, 0.62, 0.28, 0.59, 0.63, 0.57, 0.15, 0.55, 0.66, 0.1, 0.38, 0.74, 0.65, 0.17, 0.43, 0.66, 0.41, 0.8, 0.75, 0.9, 0.93, 0.52, 0.76, 0.89, 0.87, 0.76, 0.92, 0.91, 0.75, 0.61, 0.96, 0.89, 0.73, 0.97, 0.68, 0.87, 0.55, 0.85, 0.77, 0.69, 0.76, 0.98, 0.83, 0.68, 0.82, 0.74, 0.65, 0.96, 0.93, 0.54, 0.64, 0.28, 0.54, 0.52, 0.16, 0.51, 0.88, 0.6, 0.4, 0.88, 0.95, 0.33, 0.56, 0.73, 0.39, 0.06, 0.61, 0.75, 0.47, 0.19, 0.87, 0.7, 0.97, 0.94, 0.97]
null
null
null
Component of an E-cadherin/ catenin adhesion complex composed of at least E-cadherin/CDH1, beta-catenin/CTNNB1 or gamma-catenin/JUP, and potentially alpha-catenin/CTNNA1. Forms a ternary complex composed of ADAM10, CADH1 and EPHA4,
null
null
KLRG1, SPEF1, DLGAP5, AJAP1, RAPGEF2, RAB8B, PIP5K1C, PKP2, TRPV4, CTNNB1, CAV1, DDR1, TBC1D2, CTNNA1, JUP, CTNND1, PSEN1, LIMA1, CDH1, JUP, ADAM10, CADH1 , EPHA4,
null
null
null
null
Homodimer
null
79.91949
0.474025
null
null
1,950
P12830
Q96RL1
null
degron_data
CDH1
MGPWSRSLSALLLLLQVSSWLCQEPEPCHPGFDAESYTFTVPRRHLERGRVLGRVNFEDCTGRQRTAYFSLDTRFKVGTDGVITVKRPLRFHNPQIHFLVYAWDSTYRKFSTKVTLNTVGHHHRPPPHQASVSGIQAELLTFPNSSPGLRRQKRDWVIPPISCPENEKGPFPKNLVQIKSNKDKEGKVFYSITGQGADTPPVGVFIIERETGWLKVTEPLDRERIATYTLFSHAVSSNGNAVEDPMEILITVTDQNDNKPEFTQEVFKGSVMEGALPGTSVMEVTATDADDDVNTYNAAIAYTILSQDPELPDKNMFTINRNTGVISVVTTGLDRESFPTYTLVVQAADLQGEGLSTTATAVITVTDTNDNPPIFNPTTYKGQVPENEANVVITTLKVTDADAPNTPAWEAVYTILNDDGGQFVVTTNPVNNDGILKTAKGLDFEAKQQYILHVAVTNVVPFEVSLTTSTATVTVDVLDVNEAPIFVPPEKRVEVSEDFGVGQEITSYTAQEPDTFMEQKITYRIWRDTANWLEINPDTGAISTRAELDREDFEHVKNSTYTALIIATDNGSPVATGTGTLLLILSDVNDNAPIPEPRTIFFCERNPKPQVINIIDADLPPNTSPFTAELTHGASANWTIQYNDPTQESIILKPKMALEVGDYKINLKLMDNQNKDQVTTLEVSVCDCEGAAGVCRKAQPVEAGLQIPAILGILGGILALLILILLLLLFLRRRAVVKEPLLPPEDDTRDNVYYYDEEGGGEEDQDFDLSQLHRGLDARPEVTRNDVAPTLMSVPRYLPRPANPDEIGNFIDENLKAADTDPTAPPYDSLLVFDYEGSGSEAASLSSLNSSESDKDQDYDYLNEWGNRFKKLADMYGGGEDD
Homo sapiens
Cell junction, adherens junction, Cell membrane, Endosome, Golgi apparatus, trans-Golgi network, Cytoplasm, Cell junction, desmosome
Tissue enhanced (parathyroid)
{'Ciliated cells': '119.1', 'Basal respiratory cells': '71.1', 'Club cells': '97.3', 'Ionocytes': '81.0', 'Mucus glandular cells': '155.0', 'Serous glandular cells': '67.8', 'Gastric mucus-secreting cells': '133.2', 'Proximal enterocytes': '140.9', 'Paneth cells': '125.1', 'Distal enterocytes': '307.5', 'Intestinal goblet cells': '173.5', 'Exocrine glandular cells': '-0.605', 'Basal prostatic cells': '68.3', 'Prostatic glandular cells': '186.7', 'Breast glandular cells': '0.773', 'Breast myoepithelial cells': '0.700', 'Glandular and luminal cells': '313.0', 'Secretory cells': '82.3', 'Basal keratinocytes': '102.5', 'Suprabasal keratinocytes': '162.6', 'Basal squamous epithelial cells': '51.0', 'Squamous epithelial cells': '106.9', 'Alveolar cells type 1': '0.437', 'Alveolar cells type 2': '0.706', 'Salivary duct cells': '95.9', 'Ductal cells': '0.541', 'Hepatocytes': '0.600', 'Cholangiocytes': '129.7', 'Proximal tubular cells': '0.042', 'Distal tubular cells': '0.0', 'Collecting duct cells': '143.9', 'Mesothelial cells': '0.799', 'Sertoli cells': '0.252', 'Granulosa cells': '12.9', 'Enteroendocrine cells': '92.4', 'Pancreatic endocrine cells': '78.1', 'Leydig cells': '0.264', 'Excitatory neurons': '0.7', 'Inhibitory neurons': '1.3', 'Cone photoreceptor cells': '0.0', 'Rod photoreceptor cells': '0.0', 'Bipolar cells': '0.2', 'Horizontal cells': '0.6', 'Astrocytes': '0.6', 'Oligodendrocyte precursor cells': '0.5', 'Oligodendrocytes': '29.9', 'Microglial cells': '0.9', 'Muller glia cells': '0.1', 'Schwann cells': '0.131', 'Spermatogonia': '0.392', 'Spermatocytes': '0.193', 'Early spermatids': '-0.217', 'Late spermatids': '-0.290', 'Oocytes': '16.9', 'Cytotrophoblasts': '119.2', 'Syncytiotrophoblasts': '45.0', 'Extravillous trophoblasts': '24.9', 'Endothelial cells': '6.1', 'Lymphatic endothelial cells': '0.4', 'Cardiomyocytes': '0.135', 'Skeletal myocytes': '0.107', 'Smooth muscle cells': '5.8', 'Adipocytes': '2.1', 'Melanocytes': '0.335', 'Fibroblasts': '6.5', 'Peritubular cells': '0.210', 'Endometrial stromal cells': '27.7', 'Ovarian stromal cells': '0.7', 'Undifferentiated cells': '101.6', 'T-cells': '2.9', 'B-cells': '4.4', 'Plasma cells': '6.1', 'Nk-cells': '0.0', 'Granulocytes': '8.4', 'Monocytes': '0.0', 'Macrophages': '6.0', 'Hofbauer cells': '4.3', 'Kupffer cells': '1.0', 'Dendritic cells': '5.9', 'Langerhans cells': '0.304', 'Erythroid cells': '0.036', 'Adipocytes (Subcutaneous)': '-0.081', 'Adipocytes (Visceral)': '-0.209', 'Breast glandular cells (progenitors)': '0.538', 'Adipocytes (Breast)': '-0.689', 'Colon enterocytes': '0.790', 'Colon enteroendocrine cells': '0.112', 'Enteric glia cells': '-0.048', 'Mitotic cells (Colon)': '0.299', 'Mitotic cells (Heart)': '0.120', 'Podocytes': '-0.118', 'Ascending Loop of Henle cells': '0.475', 'Intercalated cells': '0.212', 'Cholangiocyte': '0.090', 'NK-cells (Liver)': '-0.005', 'Respiratory ciliated cells': '-0.012', 'Mitotic cells (Lung)': '0.071', 'NK-cells (Lung)': '-0.266', 'B-cells (Lung)': '-0.296', 'Alpha cells': '0.270', 'Beta cells': '0.152', 'Prostate glandular cells': '0.764', 'Prostate basal glandular cells': '0.540', 'Urothelial cells': '0.205', 'Keratinocyte (other)': '0.510', 'Keratinocyte (granular)': '0.055', 'Hair cortex cells': '0.080', 'Inner root sheath cells': '0.131', 'Outer root sheath cells': '0.175', 'Sebaceous gland cells': '0.156', 'Eccrine sweat gland cells': '-0.207', 'Adipocytes (Skin)': '-0.244', 'Mitotic cells (Skin)': '0.442', 'Parietal cells': '0.654', 'Chief cells': '0.649', 'Gastric mucous cells': '0.781', 'Gastric enteroendocrine cells': '0.590', 'Mitotic cells (Stomach)': '0.445', 'Parafollicular cells': '0.173', 'Thyroid glandular cells': '0.865', 'Mitotic cells (Thyroid)': '-0.081', 'Adrenal cortex cells': '0.051', 'Adrenal medulla cells': '0.087', 'Mitotic cells (Adrenal gland)': '0.072', 'Minor salivary glandular cells': '0.371', 'Minor salivary gland ductal cells': '-0.142', 'Minor salivary gland basal cells': '0.582', 'Mitotic cells (Minor salivary gland)': '0.567', 'Adipocytes (Minor salivary gland)': '0.050', 'Somatotropes': '0.121', 'Lactotropes': '0.322', 'Gonadotropes': '0.330', 'Corticotropes': '0.180', 'Thyrotropes': '0.496', 'Undifferentiated cells (Pituitary gland)': '-0.108', 'Mitotic cells (Spleen)': '-0.228', 'Platelets': '-0.050', 'Erythrocytes': '-0.158', 'Hematopoietic stem cells': '-0.211', 'B-cells (Spleen)': '0.266', 'NK-cells (Spleen)': '0.309', 'Amygdala excitatory': '1.0', 'Cerebellar inhibitory': '0.9', 'Cge interneuron': '0.7', 'Deep-layer corticothalamic and 6b': '1.5', 'Deep-layer intratelencephalic': '0.7', 'Deep-layer near-projecting': '0.7', 'Eccentric medium spiny neuron': '0.6', 'Hippocampal ca1-3': '1.9', 'Hippocampal ca4': '1.2', 'Hippocampal dentate gyrus': '1.1', 'Lamp5-lhx6 and chandelier': '0.5', 'Lower rhombic lip': '0.8', 'Mammillary body': '0.6', 'Medium spiny neuron': '0.7', 'Mge interneuron': '1.7', 'Midbrain-derived inhibitory': '0.7', 'Miscellaneous': '0.9', 'Splatter': '3.8', 'Thalamic excitatory': '0.5', 'Upper rhombic lip': '0.8', 'Upper-layer intratelencephalic': '0.6', 'Astrocyte': '4.4', 'Bergmann glia': '0.2', 'Central nervous system macrophage': '0.6', 'Choroid plexus epithelial cell': '52.1', 'Committed oligodendrocyte precursor': '41.5', 'Ependymal cell': '4.8', 'Oligodendrocyte': '53.1', 'Oligodendrocyte precursor cell': '2.4', 'Endothelial cell': '0.7', 'Pericyte': '0.3', 'Vascular associated smooth muscle cell': '0.0', 'Fibroblast': '17.4', 'Leukocyte': '1.1', 'Basophil': '0.0', 'Eosinophil': '0.0', 'Neutrophil': '0.0', 'Classical monocyte': '0.0', 'Non-classical monocyte': '0.0', 'Intermediate monocyte': '0.0', 'T-reg': '2.3', 'GdT-cell': '0.0', 'MAIT T-cell': '0.0', 'Memory CD4 T-cell': '0.0', 'Naive CD4 T-cell': '0.1', 'Memory CD8 T-cell': '0.2', 'Naive CD8 T-cell': '0.3', 'Memory B-cell': '0.0', 'Naive B-cell': '0.1', 'Plasmacytoid DC': '46.6', 'Myeloid DC': '8.5', 'NK-cell': '0.1', 'Total PBMC': '0.7', 'Vd2 gdTCR': '0.0', 'Memory CD4 T-cell Th1\\/Th17': '0.1', 'Memory CD4 T-cell Th17': '0.2', 'Memory CD4 T-cell Th2': '2.9', 'Non-Vd2 gdTCR': '0.1', 'Memory CD4 T-cell Th1': '0.3', 'Memory CD4 T-cell TFH': '0.5', 'Terminal effector memory CD4 T-cell': '0.0', 'Central memory CD8 T-cell': '4.8', 'Effector memory CD8 T-cell': '0.0', 'Terminal effector memory CD8 T-cell': '0.6', 'Non-switched memory B-cell': '0.0', 'Plasmablast': '3.3', 'Switched memory B-cell': '0.0', 'Exhausted memory B-cell': '0.7', 'Progenitor cell': '2.3', 'Memory T-reg': '1.3', 'Naive CD4 T-cell activated': '0.3', 'Naive CD8 T-cell activated': '0.6', 'Naive T-reg': '0.1'}
1O6S, 2O72, 2OMT, 2OMU, 2OMV, 2OMX, 2OMY, 2OMZ, 3FF7, 3FF8, 3L6X, 3L6Y, 4ZT1, 4ZTE, 6CXY, 6OLE, 6OLF, 6OLG, 6VEL, 7STZ, 8H62
{'Adipose Tissue': 1.2125261088039867, 'Adrenal Gland': 0.1914223992248062, 'Bladder': 39.2033519047619, 'Blood': 1.340954264800861, 'Blood Vessel': 0.3121561692883895, 'Brain': 0.8550442199091597, 'Breast': 38.54918344226579, 'Cervix Uteri': 23.539115789473684, 'Colon': 43.41292142490372, 'Esophagus': 53.97513367404844, 'Fallopian Tube': 14.900277777777776, 'Heart': 0.119140469221835, 'Kidney': 25.040449438202245, 'Liver': 26.60802654867257, 'Lung': 35.447986366782004, 'Muscle': 0.1378936151930261, 'Nerve': 17.518468982229404, 'Ovary': 3.6515122222222223, 'Pancreas': 56.89676829268293, 'Pituitary': 24.68741660777385, 'Prostate': 61.279967346938776, 'Salivary Gland': 92.01685185185184, 'Skin': 79.77571720232172, 'Small Intestine': 71.7519320855615, 'Spleen': 10.061029045643156, 'Stomach': 58.07813805013927, 'Testis': 0.8144204986149585, 'Thyroid': 135.176797856049, 'Uterus': 1.442593943661972, 'Vagina': 86.52345512820513}
UIMC1
MPRRKKKVKEVSESRNLEKKDVETTSSVSVKRKRRLEDAFIVISDSDGEEPKEENGLQKTKTKQSNRAKCLAKRKIAQMTEEEQFALALKMSEQEAREVNSQEEEEEELLRKAIAESLNSCRPSDASATRSRPLATGPSSQSHQEKTTDSGLTEGIWQLVPPSLFKGSHISQGNEAEEREEPWDHTEKTEEEPVSGSSGSWDQSSQPVFENVNVKSFDRCTGHSAEHTQCGKPQESTGRGSAFLKAVQGSGDTSRHCLPTLADAKGLQDTGGTVNYFWGIPFCPDGVDPNQYTKVILCQLEVYQKSLKMAQRQLLNKKGFGEPVLPRPPSLIQNECGQGEQASEKNECISEDMGDEDKEERQESRASDWHSKTKDFQESSIKSLKEKLLLEEEPTTSHGQSSQGIVEETSEEGNSVPASQSVAALTSKRSLVLMPESSAEEITVCPETQLSSSETFDLEREVSPGSRDILDGVRIIMADKEVGNKEDAEKEVAISTFSSSNQVSCPLCDQCFPPTKIERHAMYCNGLMEEDTVLTRRQKEAKTKSDSGTAAQTSLDIDKNEKCYLCKSLVPFREYQCHVDSCLQLAKADQGDGPEGSGRACSTVEGKWQQRLKNPKEKGHSEGRLLSFLEQSEHKTSDADIKSSETGAFRVPSPGMEEAGCSREMQSSFTRRDLNESPVKSFVSISEATDCLVDFKKQVTVQPGSRTRTKAGRGRRRKF
Homo sapiens
Nucleus
Low tissue specificity
{'Ciliated cells': '15.9', 'Basal respiratory cells': '11.4', 'Club cells': '12.8', 'Ionocytes': '10.7', 'Mucus glandular cells': '17.2', 'Serous glandular cells': '9.7', 'Gastric mucus-secreting cells': '15.9', 'Proximal enterocytes': '8.8', 'Paneth cells': '5.2', 'Distal enterocytes': '8.3', 'Intestinal goblet cells': '8.0', 'Exocrine glandular cells': '-0.764', 'Basal prostatic cells': '14.5', 'Prostatic glandular cells': '8.2', 'Breast glandular cells': '0.427', 'Breast myoepithelial cells': '0.475', 'Glandular and luminal cells': '25.6', 'Secretory cells': '17.7', 'Basal keratinocytes': '15.3', 'Suprabasal keratinocytes': '12.4', 'Basal squamous epithelial cells': '17.7', 'Squamous epithelial cells': '14.5', 'Alveolar cells type 1': '0.189', 'Alveolar cells type 2': '-0.625', 'Salivary duct cells': '14.7', 'Ductal cells': '0.532', 'Hepatocytes': '0.139', 'Cholangiocytes': '7.6', 'Proximal tubular cells': '0.136', 'Distal tubular cells': '3.1', 'Collecting duct cells': '13.6', 'Mesothelial cells': '0.409', 'Sertoli cells': '-0.102', 'Granulosa cells': '27.7', 'Enteroendocrine cells': '8.7', 'Pancreatic endocrine cells': '6.8', 'Leydig cells': '-0.115', 'Excitatory neurons': '57.5', 'Inhibitory neurons': '51.1', 'Cone photoreceptor cells': '22.1', 'Rod photoreceptor cells': '38.2', 'Bipolar cells': '20.9', 'Horizontal cells': '13.2', 'Astrocytes': '35.0', 'Oligodendrocyte precursor cells': '41.0', 'Oligodendrocytes': '47.6', 'Microglial cells': '42.0', 'Muller glia cells': '10.2', 'Schwann cells': '0.027', 'Spermatogonia': '0.265', 'Spermatocytes': '0.736', 'Early spermatids': '0.538', 'Late spermatids': '0.102', 'Oocytes': '46.3', 'Cytotrophoblasts': '13.9', 'Syncytiotrophoblasts': '6.0', 'Extravillous trophoblasts': '13.5', 'Endothelial cells': '20.2', 'Lymphatic endothelial cells': '34.0', 'Cardiomyocytes': '0.541', 'Skeletal myocytes': '-0.306', 'Smooth muscle cells': '19.9', 'Adipocytes': '24.4', 'Melanocytes': '0.090', 'Fibroblasts': '15.5', 'Peritubular cells': '-0.122', 'Endometrial stromal cells': '25.6', 'Ovarian stromal cells': '21.3', 'Undifferentiated cells': '9.2', 'T-cells': '24.8', 'B-cells': '33.2', 'Plasma cells': '24.7', 'Nk-cells': '28.3', 'Granulocytes': '15.4', 'Monocytes': '21.0', 'Macrophages': '17.2', 'Hofbauer cells': '11.1', 'Kupffer cells': '12.0', 'Dendritic cells': '13.7', 'Langerhans cells': '0.162', 'Erythroid cells': '0.064', 'Adipocytes (Subcutaneous)': '-0.562', 'Adipocytes (Visceral)': '-0.518', 'Breast glandular cells (progenitors)': '0.283', 'Adipocytes (Breast)': '-0.619', 'Colon enterocytes': '-0.249', 'Colon enteroendocrine cells': '0.200', 'Enteric glia cells': '0.272', 'Mitotic cells (Colon)': '-0.232', 'Mitotic cells (Heart)': '0.485', 'Podocytes': '-0.056', 'Ascending Loop of Henle cells': '0.387', 'Intercalated cells': '-0.022', 'Cholangiocyte': '0.360', 'NK-cells (Liver)': '-0.244', 'Respiratory ciliated cells': '0.093', 'Mitotic cells (Lung)': '-0.221', 'NK-cells (Lung)': '0.546', 'B-cells (Lung)': '0.245', 'Alpha cells': '0.334', 'Beta cells': '0.166', 'Prostate glandular cells': '-0.481', 'Prostate basal glandular cells': '0.006', 'Urothelial cells': '0.127', 'Keratinocyte (other)': '0.292', 'Keratinocyte (granular)': '-0.259', 'Hair cortex cells': '-0.177', 'Inner root sheath cells': '-0.094', 'Outer root sheath cells': '0.138', 'Sebaceous gland cells': '-0.161', 'Eccrine sweat gland cells': '-0.004', 'Adipocytes (Skin)': '-0.314', 'Mitotic cells (Skin)': '0.247', 'Parietal cells': '-0.739', 'Chief cells': '-0.595', 'Gastric mucous cells': '-0.450', 'Gastric enteroendocrine cells': '-0.442', 'Mitotic cells (Stomach)': '-0.027', 'Parafollicular cells': '0.073', 'Thyroid glandular cells': '0.157', 'Mitotic cells (Thyroid)': '-0.036', 'Adrenal cortex cells': '0.229', 'Adrenal medulla cells': '-0.188', 'Mitotic cells (Adrenal gland)': '-0.037', 'Minor salivary glandular cells': '0.554', 'Minor salivary gland ductal cells': '0.106', 'Minor salivary gland basal cells': '0.279', 'Mitotic cells (Minor salivary gland)': '0.348', 'Adipocytes (Minor salivary gland)': '0.193', 'Somatotropes': '0.003', 'Lactotropes': '-0.153', 'Gonadotropes': '-0.073', 'Corticotropes': '-0.072', 'Thyrotropes': '0.004', 'Undifferentiated cells (Pituitary gland)': '0.112', 'Mitotic cells (Spleen)': '-0.115', 'Platelets': '-0.164', 'Erythrocytes': '0.131', 'Hematopoietic stem cells': '-0.172', 'B-cells (Spleen)': '0.369', 'NK-cells (Spleen)': '0.315', 'Amygdala excitatory': '97.1', 'Cerebellar inhibitory': '66.4', 'Cge interneuron': '76.5', 'Deep-layer corticothalamic and 6b': '90.6', 'Deep-layer intratelencephalic': '97.8', 'Deep-layer near-projecting': '86.7', 'Eccentric medium spiny neuron': '92.1', 'Hippocampal ca1-3': '96.6', 'Hippocampal ca4': '91.3', 'Hippocampal dentate gyrus': '119.9', 'Lamp5-lhx6 and chandelier': '76.3', 'Lower rhombic lip': '77.5', 'Mammillary body': '91.4', 'Medium spiny neuron': '101.5', 'Mge interneuron': '81.0', 'Midbrain-derived inhibitory': '62.3', 'Miscellaneous': '88.8', 'Splatter': '77.7', 'Thalamic excitatory': '73.4', 'Upper rhombic lip': '105.6', 'Upper-layer intratelencephalic': '93.8', 'Astrocyte': '65.3', 'Bergmann glia': '87.3', 'Central nervous system macrophage': '117.6', 'Choroid plexus epithelial cell': '98.0', 'Committed oligodendrocyte precursor': '71.0', 'Ependymal cell': '87.3', 'Oligodendrocyte': '81.5', 'Oligodendrocyte precursor cell': '81.0', 'Endothelial cell': '119.5', 'Pericyte': '93.2', 'Vascular associated smooth muscle cell': '86.6', 'Fibroblast': '93.5', 'Leukocyte': '106.4', 'Basophil': '30.6', 'Eosinophil': '33.0', 'Neutrophil': '195.9', 'Classical monocyte': '49.1', 'Non-classical monocyte': '24.3', 'Intermediate monocyte': '31.1', 'T-reg': '49.4', 'GdT-cell': '9.1', 'MAIT T-cell': '51.0', 'Memory CD4 T-cell': '10.3', 'Naive CD4 T-cell': '55.7', 'Memory CD8 T-cell': '9.0', 'Naive CD8 T-cell': '47.0', 'Memory B-cell': '11.9', 'Naive B-cell': '63.1', 'Plasmacytoid DC': '41.2', 'Myeloid DC': '40.3', 'NK-cell': '48.9', 'Total PBMC': '42.8', 'Vd2 gdTCR': '40.5', 'Memory CD4 T-cell Th1\\/Th17': '55.8', 'Memory CD4 T-cell Th17': '57.5', 'Memory CD4 T-cell Th2': '54.8', 'Non-Vd2 gdTCR': '50.1', 'Memory CD4 T-cell Th1': '54.8', 'Memory CD4 T-cell TFH': '52.4', 'Terminal effector memory CD4 T-cell': '59.2', 'Central memory CD8 T-cell': '47.9', 'Effector memory CD8 T-cell': '56.2', 'Terminal effector memory CD8 T-cell': '45.4', 'Non-switched memory B-cell': '53.6', 'Plasmablast': '43.4', 'Switched memory B-cell': '64.2', 'Exhausted memory B-cell': '55.9', 'Progenitor cell': '38.8', 'Memory T-reg': '55.3', 'Naive CD4 T-cell activated': '67.8', 'Naive CD8 T-cell activated': '68.0', 'Naive T-reg': '47.1'}
2MKF, 2MKG, 2N9E, 2RR9
{'Adipose Tissue': 29.471669435215947, 'Adrenal Gland': 19.93047674418605, 'Bladder': 34.06761904761905, 'Blood': 38.04500107642626, 'Blood Vessel': 38.77668913857678, 'Brain': 11.215991294473884, 'Breast': 30.99220043572985, 'Cervix Uteri': 43.56263157894737, 'Colon': 28.37434017971759, 'Esophagus': 26.38815017301038, 'Fallopian Tube': 36.86666666666667, 'Heart': 11.78745993031359, 'Kidney': 13.648370786516852, 'Liver': 7.790026548672566, 'Lung': 34.13652249134948, 'Muscle': 15.959438356164384, 'Nerve': 37.4926817447496, 'Ovary': 47.37588888888889, 'Pancreas': 11.546228658536585, 'Pituitary': 23.14213780918728, 'Prostate': 28.76812244897959, 'Salivary Gland': 17.39922839506173, 'Skin': 25.01112769485904, 'Small Intestine': 26.423342245989303, 'Spleen': 35.413941908713696, 'Stomach': 18.903136490250695, 'Testis': 96.8357617728532, 'Thyroid': 35.04356049004594, 'Uterus': 47.847605633802814, 'Vagina': 31.31211538461538}
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null
Component of an E-cadherin/ catenin adhesion complex composed of at least E-cadherin/CDH1, beta-catenin/CTNNB1 or gamma-catenin/JUP, and potentially alpha-catenin/CTNNA1. Forms a ternary complex composed of ADAM10, CADH1 and EPHA4,
null
null
KLRG1, SPEF1, DLGAP5, AJAP1, RAPGEF2, RAB8B, PIP5K1C, PKP2, TRPV4, CTNNB1, CAV1, DDR1, TBC1D2, CTNNA1, JUP, CTNND1, PSEN1, LIMA1, CDH1, JUP, ADAM10, CADH1 , EPHA4,
null
null
null
null
Homodimer
null
79.91949
0.474025
55.347455
0.830278
975
P12830
Q96RU7
null
degron_data
CDH1
MGPWSRSLSALLLLLQVSSWLCQEPEPCHPGFDAESYTFTVPRRHLERGRVLGRVNFEDCTGRQRTAYFSLDTRFKVGTDGVITVKRPLRFHNPQIHFLVYAWDSTYRKFSTKVTLNTVGHHHRPPPHQASVSGIQAELLTFPNSSPGLRRQKRDWVIPPISCPENEKGPFPKNLVQIKSNKDKEGKVFYSITGQGADTPPVGVFIIERETGWLKVTEPLDRERIATYTLFSHAVSSNGNAVEDPMEILITVTDQNDNKPEFTQEVFKGSVMEGALPGTSVMEVTATDADDDVNTYNAAIAYTILSQDPELPDKNMFTINRNTGVISVVTTGLDRESFPTYTLVVQAADLQGEGLSTTATAVITVTDTNDNPPIFNPTTYKGQVPENEANVVITTLKVTDADAPNTPAWEAVYTILNDDGGQFVVTTNPVNNDGILKTAKGLDFEAKQQYILHVAVTNVVPFEVSLTTSTATVTVDVLDVNEAPIFVPPEKRVEVSEDFGVGQEITSYTAQEPDTFMEQKITYRIWRDTANWLEINPDTGAISTRAELDREDFEHVKNSTYTALIIATDNGSPVATGTGTLLLILSDVNDNAPIPEPRTIFFCERNPKPQVINIIDADLPPNTSPFTAELTHGASANWTIQYNDPTQESIILKPKMALEVGDYKINLKLMDNQNKDQVTTLEVSVCDCEGAAGVCRKAQPVEAGLQIPAILGILGGILALLILILLLLLFLRRRAVVKEPLLPPEDDTRDNVYYYDEEGGGEEDQDFDLSQLHRGLDARPEVTRNDVAPTLMSVPRYLPRPANPDEIGNFIDENLKAADTDPTAPPYDSLLVFDYEGSGSEAASLSSLNSSESDKDQDYDYLNEWGNRFKKLADMYGGGEDD
Homo sapiens
Cell junction, adherens junction, Cell membrane, Endosome, Golgi apparatus, trans-Golgi network, Cytoplasm, Cell junction, desmosome
Tissue enhanced (parathyroid)
{'Ciliated cells': '119.1', 'Basal respiratory cells': '71.1', 'Club cells': '97.3', 'Ionocytes': '81.0', 'Mucus glandular cells': '155.0', 'Serous glandular cells': '67.8', 'Gastric mucus-secreting cells': '133.2', 'Proximal enterocytes': '140.9', 'Paneth cells': '125.1', 'Distal enterocytes': '307.5', 'Intestinal goblet cells': '173.5', 'Exocrine glandular cells': '-0.605', 'Basal prostatic cells': '68.3', 'Prostatic glandular cells': '186.7', 'Breast glandular cells': '0.773', 'Breast myoepithelial cells': '0.700', 'Glandular and luminal cells': '313.0', 'Secretory cells': '82.3', 'Basal keratinocytes': '102.5', 'Suprabasal keratinocytes': '162.6', 'Basal squamous epithelial cells': '51.0', 'Squamous epithelial cells': '106.9', 'Alveolar cells type 1': '0.437', 'Alveolar cells type 2': '0.706', 'Salivary duct cells': '95.9', 'Ductal cells': '0.541', 'Hepatocytes': '0.600', 'Cholangiocytes': '129.7', 'Proximal tubular cells': '0.042', 'Distal tubular cells': '0.0', 'Collecting duct cells': '143.9', 'Mesothelial cells': '0.799', 'Sertoli cells': '0.252', 'Granulosa cells': '12.9', 'Enteroendocrine cells': '92.4', 'Pancreatic endocrine cells': '78.1', 'Leydig cells': '0.264', 'Excitatory neurons': '0.7', 'Inhibitory neurons': '1.3', 'Cone photoreceptor cells': '0.0', 'Rod photoreceptor cells': '0.0', 'Bipolar cells': '0.2', 'Horizontal cells': '0.6', 'Astrocytes': '0.6', 'Oligodendrocyte precursor cells': '0.5', 'Oligodendrocytes': '29.9', 'Microglial cells': '0.9', 'Muller glia cells': '0.1', 'Schwann cells': '0.131', 'Spermatogonia': '0.392', 'Spermatocytes': '0.193', 'Early spermatids': '-0.217', 'Late spermatids': '-0.290', 'Oocytes': '16.9', 'Cytotrophoblasts': '119.2', 'Syncytiotrophoblasts': '45.0', 'Extravillous trophoblasts': '24.9', 'Endothelial cells': '6.1', 'Lymphatic endothelial cells': '0.4', 'Cardiomyocytes': '0.135', 'Skeletal myocytes': '0.107', 'Smooth muscle cells': '5.8', 'Adipocytes': '2.1', 'Melanocytes': '0.335', 'Fibroblasts': '6.5', 'Peritubular cells': '0.210', 'Endometrial stromal cells': '27.7', 'Ovarian stromal cells': '0.7', 'Undifferentiated cells': '101.6', 'T-cells': '2.9', 'B-cells': '4.4', 'Plasma cells': '6.1', 'Nk-cells': '0.0', 'Granulocytes': '8.4', 'Monocytes': '0.0', 'Macrophages': '6.0', 'Hofbauer cells': '4.3', 'Kupffer cells': '1.0', 'Dendritic cells': '5.9', 'Langerhans cells': '0.304', 'Erythroid cells': '0.036', 'Adipocytes (Subcutaneous)': '-0.081', 'Adipocytes (Visceral)': '-0.209', 'Breast glandular cells (progenitors)': '0.538', 'Adipocytes (Breast)': '-0.689', 'Colon enterocytes': '0.790', 'Colon enteroendocrine cells': '0.112', 'Enteric glia cells': '-0.048', 'Mitotic cells (Colon)': '0.299', 'Mitotic cells (Heart)': '0.120', 'Podocytes': '-0.118', 'Ascending Loop of Henle cells': '0.475', 'Intercalated cells': '0.212', 'Cholangiocyte': '0.090', 'NK-cells (Liver)': '-0.005', 'Respiratory ciliated cells': '-0.012', 'Mitotic cells (Lung)': '0.071', 'NK-cells (Lung)': '-0.266', 'B-cells (Lung)': '-0.296', 'Alpha cells': '0.270', 'Beta cells': '0.152', 'Prostate glandular cells': '0.764', 'Prostate basal glandular cells': '0.540', 'Urothelial cells': '0.205', 'Keratinocyte (other)': '0.510', 'Keratinocyte (granular)': '0.055', 'Hair cortex cells': '0.080', 'Inner root sheath cells': '0.131', 'Outer root sheath cells': '0.175', 'Sebaceous gland cells': '0.156', 'Eccrine sweat gland cells': '-0.207', 'Adipocytes (Skin)': '-0.244', 'Mitotic cells (Skin)': '0.442', 'Parietal cells': '0.654', 'Chief cells': '0.649', 'Gastric mucous cells': '0.781', 'Gastric enteroendocrine cells': '0.590', 'Mitotic cells (Stomach)': '0.445', 'Parafollicular cells': '0.173', 'Thyroid glandular cells': '0.865', 'Mitotic cells (Thyroid)': '-0.081', 'Adrenal cortex cells': '0.051', 'Adrenal medulla cells': '0.087', 'Mitotic cells (Adrenal gland)': '0.072', 'Minor salivary glandular cells': '0.371', 'Minor salivary gland ductal cells': '-0.142', 'Minor salivary gland basal cells': '0.582', 'Mitotic cells (Minor salivary gland)': '0.567', 'Adipocytes (Minor salivary gland)': '0.050', 'Somatotropes': '0.121', 'Lactotropes': '0.322', 'Gonadotropes': '0.330', 'Corticotropes': '0.180', 'Thyrotropes': '0.496', 'Undifferentiated cells (Pituitary gland)': '-0.108', 'Mitotic cells (Spleen)': '-0.228', 'Platelets': '-0.050', 'Erythrocytes': '-0.158', 'Hematopoietic stem cells': '-0.211', 'B-cells (Spleen)': '0.266', 'NK-cells (Spleen)': '0.309', 'Amygdala excitatory': '1.0', 'Cerebellar inhibitory': '0.9', 'Cge interneuron': '0.7', 'Deep-layer corticothalamic and 6b': '1.5', 'Deep-layer intratelencephalic': '0.7', 'Deep-layer near-projecting': '0.7', 'Eccentric medium spiny neuron': '0.6', 'Hippocampal ca1-3': '1.9', 'Hippocampal ca4': '1.2', 'Hippocampal dentate gyrus': '1.1', 'Lamp5-lhx6 and chandelier': '0.5', 'Lower rhombic lip': '0.8', 'Mammillary body': '0.6', 'Medium spiny neuron': '0.7', 'Mge interneuron': '1.7', 'Midbrain-derived inhibitory': '0.7', 'Miscellaneous': '0.9', 'Splatter': '3.8', 'Thalamic excitatory': '0.5', 'Upper rhombic lip': '0.8', 'Upper-layer intratelencephalic': '0.6', 'Astrocyte': '4.4', 'Bergmann glia': '0.2', 'Central nervous system macrophage': '0.6', 'Choroid plexus epithelial cell': '52.1', 'Committed oligodendrocyte precursor': '41.5', 'Ependymal cell': '4.8', 'Oligodendrocyte': '53.1', 'Oligodendrocyte precursor cell': '2.4', 'Endothelial cell': '0.7', 'Pericyte': '0.3', 'Vascular associated smooth muscle cell': '0.0', 'Fibroblast': '17.4', 'Leukocyte': '1.1', 'Basophil': '0.0', 'Eosinophil': '0.0', 'Neutrophil': '0.0', 'Classical monocyte': '0.0', 'Non-classical monocyte': '0.0', 'Intermediate monocyte': '0.0', 'T-reg': '2.3', 'GdT-cell': '0.0', 'MAIT T-cell': '0.0', 'Memory CD4 T-cell': '0.0', 'Naive CD4 T-cell': '0.1', 'Memory CD8 T-cell': '0.2', 'Naive CD8 T-cell': '0.3', 'Memory B-cell': '0.0', 'Naive B-cell': '0.1', 'Plasmacytoid DC': '46.6', 'Myeloid DC': '8.5', 'NK-cell': '0.1', 'Total PBMC': '0.7', 'Vd2 gdTCR': '0.0', 'Memory CD4 T-cell Th1\\/Th17': '0.1', 'Memory CD4 T-cell Th17': '0.2', 'Memory CD4 T-cell Th2': '2.9', 'Non-Vd2 gdTCR': '0.1', 'Memory CD4 T-cell Th1': '0.3', 'Memory CD4 T-cell TFH': '0.5', 'Terminal effector memory CD4 T-cell': '0.0', 'Central memory CD8 T-cell': '4.8', 'Effector memory CD8 T-cell': '0.0', 'Terminal effector memory CD8 T-cell': '0.6', 'Non-switched memory B-cell': '0.0', 'Plasmablast': '3.3', 'Switched memory B-cell': '0.0', 'Exhausted memory B-cell': '0.7', 'Progenitor cell': '2.3', 'Memory T-reg': '1.3', 'Naive CD4 T-cell activated': '0.3', 'Naive CD8 T-cell activated': '0.6', 'Naive T-reg': '0.1'}
1O6S, 2O72, 2OMT, 2OMU, 2OMV, 2OMX, 2OMY, 2OMZ, 3FF7, 3FF8, 3L6X, 3L6Y, 4ZT1, 4ZTE, 6CXY, 6OLE, 6OLF, 6OLG, 6VEL, 7STZ, 8H62
{'Adipose Tissue': 1.2125261088039867, 'Adrenal Gland': 0.1914223992248062, 'Bladder': 39.2033519047619, 'Blood': 1.340954264800861, 'Blood Vessel': 0.3121561692883895, 'Brain': 0.8550442199091597, 'Breast': 38.54918344226579, 'Cervix Uteri': 23.539115789473684, 'Colon': 43.41292142490372, 'Esophagus': 53.97513367404844, 'Fallopian Tube': 14.900277777777776, 'Heart': 0.119140469221835, 'Kidney': 25.040449438202245, 'Liver': 26.60802654867257, 'Lung': 35.447986366782004, 'Muscle': 0.1378936151930261, 'Nerve': 17.518468982229404, 'Ovary': 3.6515122222222223, 'Pancreas': 56.89676829268293, 'Pituitary': 24.68741660777385, 'Prostate': 61.279967346938776, 'Salivary Gland': 92.01685185185184, 'Skin': 79.77571720232172, 'Small Intestine': 71.7519320855615, 'Spleen': 10.061029045643156, 'Stomach': 58.07813805013927, 'Testis': 0.8144204986149585, 'Thyroid': 135.176797856049, 'Uterus': 1.442593943661972, 'Vagina': 86.52345512820513}
TRIB3
MRATPLAAPAGSLSRKKRLELDDNLDTERPVQKRARSGPQPRLPPCLLPLSPPTAPDRATAVATASRLGPYVLLEPEEGGRAYQALHCPTGTEYTCKVYPVQEALAVLEPYARLPPHKHVARPTEVLAGTQLLYAFFTRTHGDMHSLVRSRHRIPEPEAAVLFRQMATALAHCHQHGLVLRDLKLCRFVFADRERKKLVLENLEDSCVLTGPDDSLWDKHACPAYVGPEILSSRASYSGKAADVWSLGVALFTMLAGHYPFQDSEPVLLFGKIRRGAYALPAGLSAPARCLVRCLLRREPAERLTATGILLHPWLRQDPMPLAPTRSHLWEAAQVVPDGLGLDEAREEEGDREVVLYG
Homo sapiens
Nucleus
Tissue enhanced (liver)
{'Ciliated cells': '1.8', 'Basal respiratory cells': '19.1', 'Club cells': '7.7', 'Ionocytes': '10.3', 'Mucus glandular cells': '3.2', 'Serous glandular cells': '3.1', 'Gastric mucus-secreting cells': '0.0', 'Proximal enterocytes': '0.0', 'Paneth cells': '4.5', 'Distal enterocytes': '3.1', 'Intestinal goblet cells': '7.9', 'Exocrine glandular cells': '-0.585', 'Basal prostatic cells': '6.8', 'Prostatic glandular cells': '7.6', 'Breast glandular cells': '0.516', 'Breast myoepithelial cells': '0.190', 'Glandular and luminal cells': '3.2', 'Secretory cells': '0.4', 'Basal keratinocytes': '4.5', 'Suprabasal keratinocytes': '6.3', 'Basal squamous epithelial cells': '2.9', 'Squamous epithelial cells': '3.7', 'Alveolar cells type 1': '-0.097', 'Alveolar cells type 2': '0.445', 'Salivary duct cells': '1.6', 'Ductal cells': '0.472', 'Hepatocytes': '-0.068', 'Cholangiocytes': '11.4', 'Proximal tubular cells': '0.017', 'Distal tubular cells': '0.0', 'Collecting duct cells': '3.9', 'Mesothelial cells': '-0.012', 'Sertoli cells': '0.384', 'Granulosa cells': '2.8', 'Enteroendocrine cells': '3.3', 'Pancreatic endocrine cells': '15.3', 'Leydig cells': '0.459', 'Excitatory neurons': '2.1', 'Inhibitory neurons': '2.9', 'Cone photoreceptor cells': '5.1', 'Rod photoreceptor cells': '5.7', 'Bipolar cells': '5.7', 'Horizontal cells': '2.5', 'Astrocytes': '0.3', 'Oligodendrocyte precursor cells': '0.9', 'Oligodendrocytes': '0.6', 'Microglial cells': '0.0', 'Muller glia cells': '1.0', 'Schwann cells': '0.017', 'Spermatogonia': '0.357', 'Spermatocytes': '0.047', 'Early spermatids': '-0.377', 'Late spermatids': '-0.472', 'Oocytes': '1.5', 'Cytotrophoblasts': '14.5', 'Syncytiotrophoblasts': '7.5', 'Extravillous trophoblasts': '4.8', 'Endothelial cells': '8.7', 'Lymphatic endothelial cells': '15.3', 'Cardiomyocytes': '-0.226', 'Skeletal myocytes': '0.021', 'Smooth muscle cells': '3.7', 'Adipocytes': '7.4', 'Melanocytes': '0.009', 'Fibroblasts': '5.1', 'Peritubular cells': '0.319', 'Endometrial stromal cells': '1.4', 'Ovarian stromal cells': '2.1', 'Undifferentiated cells': '4.9', 'T-cells': '5.5', 'B-cells': '6.5', 'Plasma cells': '7.8', 'Nk-cells': '8.3', 'Granulocytes': '7.1', 'Monocytes': '3.5', 'Macrophages': '3.4', 'Hofbauer cells': '6.3', 'Kupffer cells': '7.2', 'Dendritic cells': '0.0', 'Langerhans cells': '0.135', 'Erythroid cells': '-0.072', 'Adipocytes (Subcutaneous)': '-0.194', 'Adipocytes (Visceral)': '-0.106', 'Breast glandular cells (progenitors)': '0.133', 'Adipocytes (Breast)': '-0.396', 'Colon enterocytes': '0.181', 'Colon enteroendocrine cells': '0.036', 'Enteric glia cells': '0.097', 'Mitotic cells (Colon)': '0.342', 'Mitotic cells (Heart)': '0.264', 'Podocytes': '-0.149', 'Ascending Loop of Henle cells': '0.188', 'Intercalated cells': '-0.138', 'Cholangiocyte': '0.210', 'NK-cells (Liver)': '-0.261', 'Respiratory ciliated cells': '-0.159', 'Mitotic cells (Lung)': '0.251', 'NK-cells (Lung)': '-0.383', 'B-cells (Lung)': '-0.300', 'Alpha cells': '0.339', 'Beta cells': '0.136', 'Prostate glandular cells': '0.493', 'Prostate basal glandular cells': '0.392', 'Urothelial cells': '0.179', 'Keratinocyte (other)': '0.247', 'Keratinocyte (granular)': '0.624', 'Hair cortex cells': '-0.304', 'Inner root sheath cells': '-0.314', 'Outer root sheath cells': '-0.447', 'Sebaceous gland cells': '0.111', 'Eccrine sweat gland cells': '-0.420', 'Adipocytes (Skin)': '-0.159', 'Mitotic cells (Skin)': '-0.134', 'Parietal cells': '0.080', 'Chief cells': '0.330', 'Gastric mucous cells': '0.320', 'Gastric enteroendocrine cells': '0.396', 'Mitotic cells (Stomach)': '0.248', 'Parafollicular cells': '-0.029', 'Thyroid glandular cells': '0.067', 'Mitotic cells (Thyroid)': '0.072', 'Adrenal cortex cells': '0.482', 'Adrenal medulla cells': '0.040', 'Mitotic cells (Adrenal gland)': '0.014', 'Minor salivary glandular cells': '0.551', 'Minor salivary gland ductal cells': '-0.015', 'Minor salivary gland basal cells': '0.039', 'Mitotic cells (Minor salivary gland)': '0.113', 'Adipocytes (Minor salivary gland)': '0.045', 'Somatotropes': '0.349', 'Lactotropes': '0.008', 'Gonadotropes': '-0.011', 'Corticotropes': '-0.075', 'Thyrotropes': '-0.128', 'Undifferentiated cells (Pituitary gland)': '-0.215', 'Mitotic cells (Spleen)': '-0.185', 'Platelets': '-0.036', 'Erythrocytes': '0.035', 'Hematopoietic stem cells': '-0.163', 'B-cells (Spleen)': '0.142', 'NK-cells (Spleen)': '0.189', 'Amygdala excitatory': '6.5', 'Cerebellar inhibitory': '3.1', 'Cge interneuron': '6.4', 'Deep-layer corticothalamic and 6b': '6.3', 'Deep-layer intratelencephalic': '7.0', 'Deep-layer near-projecting': '4.4', 'Eccentric medium spiny neuron': '4.0', 'Hippocampal ca1-3': '5.9', 'Hippocampal ca4': '5.9', 'Hippocampal dentate gyrus': '2.2', 'Lamp5-lhx6 and chandelier': '5.1', 'Lower rhombic lip': '6.0', 'Mammillary body': '4.7', 'Medium spiny neuron': '1.7', 'Mge interneuron': '5.1', 'Midbrain-derived inhibitory': '3.1', 'Miscellaneous': '6.2', 'Splatter': '5.8', 'Thalamic excitatory': '4.0', 'Upper rhombic lip': '3.8', 'Upper-layer intratelencephalic': '6.4', 'Astrocyte': '0.8', 'Bergmann glia': '1.4', 'Central nervous system macrophage': '0.6', 'Choroid plexus epithelial cell': '1.2', 'Committed oligodendrocyte precursor': '1.6', 'Ependymal cell': '1.1', 'Oligodendrocyte': '0.8', 'Oligodendrocyte precursor cell': '4.1', 'Endothelial cell': '5.6', 'Pericyte': '3.6', 'Vascular associated smooth muscle cell': '1.8', 'Fibroblast': '0.9', 'Leukocyte': '4.9', 'Basophil': '6.8', 'Eosinophil': '1.3', 'Neutrophil': '14.4', 'Classical monocyte': '10.8', 'Non-classical monocyte': '5.7', 'Intermediate monocyte': '16.5', 'T-reg': '16.3', 'GdT-cell': '12.0', 'MAIT T-cell': '13.4', 'Memory CD4 T-cell': '11.2', 'Naive CD4 T-cell': '4.9', 'Memory CD8 T-cell': '13.7', 'Naive CD8 T-cell': '3.1', 'Memory B-cell': '19.3', 'Naive B-cell': '3.4', 'Plasmacytoid DC': '3.8', 'Myeloid DC': '11.6', 'NK-cell': '12.4', 'Total PBMC': '17.4', 'Vd2 gdTCR': '19.9', 'Memory CD4 T-cell TFH': '6.5', 'Memory CD4 T-cell Th2': '5.2', 'Memory CD4 T-cell Th17': '4.5', 'Memory CD4 T-cell Th1\\/Th17': '3.3', 'Non-Vd2 gdTCR': '25.2', 'Memory CD4 T-cell Th1': '4.9', 'Terminal effector memory CD4 T-cell': '26.1', 'Central memory CD8 T-cell': '10.3', 'Effector memory CD8 T-cell': '21.7', 'Terminal effector memory CD8 T-cell': '22.5', 'Switched memory B-cell': '30.6', 'Plasmablast': '39.1', 'Non-switched memory B-cell': '20.8', 'Exhausted memory B-cell': '32.3', 'Progenitor cell': '10.5', 'Naive CD4 T-cell activated': '10.0', 'Naive CD8 T-cell activated': '10.9', 'Memory T-reg': '8.8', 'Naive T-reg': '7.3'}
null
{'Adipose Tissue': 8.809264950166112, 'Adrenal Gland': 17.54763953488372, 'Bladder': 6.9800523809523805, 'Blood': 9.43186975242196, 'Blood Vessel': 4.216821797752809, 'Brain': 3.4900453065859196, 'Breast': 11.200418300653595, 'Cervix Uteri': 5.766473684210527, 'Colon': 3.77694351732991, 'Esophagus': 10.10880795847751, 'Fallopian Tube': 3.9268888888888887, 'Heart': 2.3147218350754937, 'Kidney': 5.262460674157303, 'Liver': 43.32687610619469, 'Lung': 24.430044982698963, 'Muscle': 1.1405036239103363, 'Nerve': 8.425048465266558, 'Ovary': 5.009766666666667, 'Pancreas': 9.007713414634146, 'Pituitary': 21.826416961130743, 'Prostate': 11.24681224489796, 'Salivary Gland': 12.413938271604938, 'Skin': 30.488616915422888, 'Small Intestine': 6.5698743315508015, 'Spleen': 16.02609958506224, 'Stomach': 9.364656824512537, 'Testis': 2.5564221606648196, 'Thyroid': 10.912295558958652, 'Uterus': 4.951273943661972, 'Vagina': 7.594839743589744}
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[1.0, 1.0, 1.0, 0.96, 0.99, 0.97, 0.95, 0.99, 0.97, 0.99, 1.0, 0.99, 1.0, 0.99, 0.99, 0.99, 0.96, 0.81, 0.96, 0.71, 0.87, 0.98, 0.82, 0.9, 1.0, 0.92, 0.98, 1.0, 0.94, 0.94, 0.81, 0.93, 0.89, 0.96, 0.94, 0.94, 0.95, 0.71, 0.96, 0.83, 0.69, 0.93, 0.15, 0.47, 0.71, 0.36, 0.53, 0.9, 0.41, 0.34, 0.29, 0.91, 0.72, 0.89, 0.82, 0.65, 0.83, 0.9, 0.47, 0.61, 0.79, 0.13, 0.66, 0.63, 0.66, 0.26, 0.74, 0.16, 0.57, 0.32, 0.03, 0.24, 0.0, 0.41, 0.76, 0.56, 0.37, 0.99, 0.87, 0.44, 0.43, 0.17, 0.05, 0.41, 0.02, 0.35, 0.16, 0.51, 0.73, 0.65, 0.54, 0.38, 0.51, 0.15, 0.09, 0.0, 0.09, 0.1, 0.05, 0.36, 0.31, 0.79, 0.39, 0.15, 0.8, 0.65, 0.14, 0.34, 0.44, 0.01, 0.09, 0.77, 0.6, 0.06, 0.49, 0.72, 0.25, 0.77, 0.11, 0.11, 0.19, 0.45, 0.24, 0.53, 0.37, 0.41, 0.24, 0.77, 0.46, 0.92, 0.7, 0.14, 0.02, 0.12, 0.01, 0.0, 0.06, 0.63, 0.43, 0.39, 0.24, 0.45, 0.22, 0.0, 0.07, 0.46, 0.1, 0.0, 0.52, 0.69, 0.42, 0.67, 0.7, 0.02, 0.53, 0.24, 0.36, 0.35, 0.0, 0.14, 0.32, 0.03, 0.0, 0.4, 0.12, 0.0, 0.01, 0.25, 0.02, 0.01, 0.04, 0.12, 0.0, 0.1, 0.67, 0.4, 0.15, 0.02, 0.0, 0.0, 0.16, 0.19, 0.03, 0.1, 0.0, 0.34, 0.07, 0.03, 0.06, 0.0, 0.37, 0.25, 0.79, 0.69, 0.51, 0.6, 0.45, 0.0, 0.11, 0.0, 0.27, 0.09, 0.03, 0.27, 0.61, 0.2, 0.24, 0.23, 0.16, 0.95, 0.54, 0.88, 0.66, 0.17, 0.39, 0.07, 0.69, 0.34, 0.42, 0.31, 0.03, 0.01, 0.09, 0.12, 0.0, 0.0, 0.02, 0.06, 0.14, 0.04, 0.19, 0.64, 0.25, 0.97, 0.53, 0.41, 0.08, 0.32, 0.01, 0.26, 0.12, 0.1, 0.02, 0.02, 0.0, 0.06, 0.02, 0.0, 0.0, 0.01, 0.0, 0.02, 0.01, 0.0, 0.05, 0.19, 0.14, 0.28, 0.04, 0.16, 0.02, 0.28, 0.32, 0.93, 0.63, 0.52, 0.75, 0.53, 0.06, 0.17, 0.16, 0.3, 0.0, 0.39, 0.65, 0.22, 0.67, 0.23, 0.77, 0.17, 0.26, 0.94, 0.95, 0.19, 0.29, 0.69, 0.27, 0.01, 0.29, 0.42, 0.0, 0.0, 0.5, 0.28, 0.0, 0.06, 0.44, 0.65, 0.57, 0.22, 0.8, 0.53, 0.08, 0.31, 0.69, 0.04, 0.41, 0.21, 0.0, 0.31, 0.56, 0.11, 0.57, 0.03, 0.06, 0.63, 0.59, 0.89, 0.58, 0.85, 0.89, 0.72, 0.75, 0.89, 0.77, 0.96, 0.78, 0.95, 0.97, 0.87, 0.96, 0.87, 0.84, 0.97, 0.91, 0.9, 0.89, 0.9, 0.9, 0.86, 0.92, 0.92, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 0.99, 0.91, 1.0, 0.97, 1.0]
null
Component of an E-cadherin/ catenin adhesion complex composed of at least E-cadherin/CDH1, beta-catenin/CTNNB1 or gamma-catenin/JUP, and potentially alpha-catenin/CTNNA1. Forms a ternary complex composed of ADAM10, CADH1 and EPHA4,
null
null
KLRG1, SPEF1, DLGAP5, AJAP1, RAPGEF2, RAB8B, PIP5K1C, PKP2, TRPV4, CTNNB1, CAV1, DDR1, TBC1D2, CTNNA1, JUP, CTNND1, PSEN1, LIMA1, CDH1, JUP, ADAM10, CADH1 , EPHA4,
null
null
null
null
Homodimer
null
79.91949
0.474025
77.641788
0.46176
2,088
P12830
Q99618
null
degron_data
CDH1
MGPWSRSLSALLLLLQVSSWLCQEPEPCHPGFDAESYTFTVPRRHLERGRVLGRVNFEDCTGRQRTAYFSLDTRFKVGTDGVITVKRPLRFHNPQIHFLVYAWDSTYRKFSTKVTLNTVGHHHRPPPHQASVSGIQAELLTFPNSSPGLRRQKRDWVIPPISCPENEKGPFPKNLVQIKSNKDKEGKVFYSITGQGADTPPVGVFIIERETGWLKVTEPLDRERIATYTLFSHAVSSNGNAVEDPMEILITVTDQNDNKPEFTQEVFKGSVMEGALPGTSVMEVTATDADDDVNTYNAAIAYTILSQDPELPDKNMFTINRNTGVISVVTTGLDRESFPTYTLVVQAADLQGEGLSTTATAVITVTDTNDNPPIFNPTTYKGQVPENEANVVITTLKVTDADAPNTPAWEAVYTILNDDGGQFVVTTNPVNNDGILKTAKGLDFEAKQQYILHVAVTNVVPFEVSLTTSTATVTVDVLDVNEAPIFVPPEKRVEVSEDFGVGQEITSYTAQEPDTFMEQKITYRIWRDTANWLEINPDTGAISTRAELDREDFEHVKNSTYTALIIATDNGSPVATGTGTLLLILSDVNDNAPIPEPRTIFFCERNPKPQVINIIDADLPPNTSPFTAELTHGASANWTIQYNDPTQESIILKPKMALEVGDYKINLKLMDNQNKDQVTTLEVSVCDCEGAAGVCRKAQPVEAGLQIPAILGILGGILALLILILLLLLFLRRRAVVKEPLLPPEDDTRDNVYYYDEEGGGEEDQDFDLSQLHRGLDARPEVTRNDVAPTLMSVPRYLPRPANPDEIGNFIDENLKAADTDPTAPPYDSLLVFDYEGSGSEAASLSSLNSSESDKDQDYDYLNEWGNRFKKLADMYGGGEDD
Homo sapiens
Cell junction, adherens junction, Cell membrane, Endosome, Golgi apparatus, trans-Golgi network, Cytoplasm, Cell junction, desmosome
Tissue enhanced (parathyroid)
{'Ciliated cells': '119.1', 'Basal respiratory cells': '71.1', 'Club cells': '97.3', 'Ionocytes': '81.0', 'Mucus glandular cells': '155.0', 'Serous glandular cells': '67.8', 'Gastric mucus-secreting cells': '133.2', 'Proximal enterocytes': '140.9', 'Paneth cells': '125.1', 'Distal enterocytes': '307.5', 'Intestinal goblet cells': '173.5', 'Exocrine glandular cells': '-0.605', 'Basal prostatic cells': '68.3', 'Prostatic glandular cells': '186.7', 'Breast glandular cells': '0.773', 'Breast myoepithelial cells': '0.700', 'Glandular and luminal cells': '313.0', 'Secretory cells': '82.3', 'Basal keratinocytes': '102.5', 'Suprabasal keratinocytes': '162.6', 'Basal squamous epithelial cells': '51.0', 'Squamous epithelial cells': '106.9', 'Alveolar cells type 1': '0.437', 'Alveolar cells type 2': '0.706', 'Salivary duct cells': '95.9', 'Ductal cells': '0.541', 'Hepatocytes': '0.600', 'Cholangiocytes': '129.7', 'Proximal tubular cells': '0.042', 'Distal tubular cells': '0.0', 'Collecting duct cells': '143.9', 'Mesothelial cells': '0.799', 'Sertoli cells': '0.252', 'Granulosa cells': '12.9', 'Enteroendocrine cells': '92.4', 'Pancreatic endocrine cells': '78.1', 'Leydig cells': '0.264', 'Excitatory neurons': '0.7', 'Inhibitory neurons': '1.3', 'Cone photoreceptor cells': '0.0', 'Rod photoreceptor cells': '0.0', 'Bipolar cells': '0.2', 'Horizontal cells': '0.6', 'Astrocytes': '0.6', 'Oligodendrocyte precursor cells': '0.5', 'Oligodendrocytes': '29.9', 'Microglial cells': '0.9', 'Muller glia cells': '0.1', 'Schwann cells': '0.131', 'Spermatogonia': '0.392', 'Spermatocytes': '0.193', 'Early spermatids': '-0.217', 'Late spermatids': '-0.290', 'Oocytes': '16.9', 'Cytotrophoblasts': '119.2', 'Syncytiotrophoblasts': '45.0', 'Extravillous trophoblasts': '24.9', 'Endothelial cells': '6.1', 'Lymphatic endothelial cells': '0.4', 'Cardiomyocytes': '0.135', 'Skeletal myocytes': '0.107', 'Smooth muscle cells': '5.8', 'Adipocytes': '2.1', 'Melanocytes': '0.335', 'Fibroblasts': '6.5', 'Peritubular cells': '0.210', 'Endometrial stromal cells': '27.7', 'Ovarian stromal cells': '0.7', 'Undifferentiated cells': '101.6', 'T-cells': '2.9', 'B-cells': '4.4', 'Plasma cells': '6.1', 'Nk-cells': '0.0', 'Granulocytes': '8.4', 'Monocytes': '0.0', 'Macrophages': '6.0', 'Hofbauer cells': '4.3', 'Kupffer cells': '1.0', 'Dendritic cells': '5.9', 'Langerhans cells': '0.304', 'Erythroid cells': '0.036', 'Adipocytes (Subcutaneous)': '-0.081', 'Adipocytes (Visceral)': '-0.209', 'Breast glandular cells (progenitors)': '0.538', 'Adipocytes (Breast)': '-0.689', 'Colon enterocytes': '0.790', 'Colon enteroendocrine cells': '0.112', 'Enteric glia cells': '-0.048', 'Mitotic cells (Colon)': '0.299', 'Mitotic cells (Heart)': '0.120', 'Podocytes': '-0.118', 'Ascending Loop of Henle cells': '0.475', 'Intercalated cells': '0.212', 'Cholangiocyte': '0.090', 'NK-cells (Liver)': '-0.005', 'Respiratory ciliated cells': '-0.012', 'Mitotic cells (Lung)': '0.071', 'NK-cells (Lung)': '-0.266', 'B-cells (Lung)': '-0.296', 'Alpha cells': '0.270', 'Beta cells': '0.152', 'Prostate glandular cells': '0.764', 'Prostate basal glandular cells': '0.540', 'Urothelial cells': '0.205', 'Keratinocyte (other)': '0.510', 'Keratinocyte (granular)': '0.055', 'Hair cortex cells': '0.080', 'Inner root sheath cells': '0.131', 'Outer root sheath cells': '0.175', 'Sebaceous gland cells': '0.156', 'Eccrine sweat gland cells': '-0.207', 'Adipocytes (Skin)': '-0.244', 'Mitotic cells (Skin)': '0.442', 'Parietal cells': '0.654', 'Chief cells': '0.649', 'Gastric mucous cells': '0.781', 'Gastric enteroendocrine cells': '0.590', 'Mitotic cells (Stomach)': '0.445', 'Parafollicular cells': '0.173', 'Thyroid glandular cells': '0.865', 'Mitotic cells (Thyroid)': '-0.081', 'Adrenal cortex cells': '0.051', 'Adrenal medulla cells': '0.087', 'Mitotic cells (Adrenal gland)': '0.072', 'Minor salivary glandular cells': '0.371', 'Minor salivary gland ductal cells': '-0.142', 'Minor salivary gland basal cells': '0.582', 'Mitotic cells (Minor salivary gland)': '0.567', 'Adipocytes (Minor salivary gland)': '0.050', 'Somatotropes': '0.121', 'Lactotropes': '0.322', 'Gonadotropes': '0.330', 'Corticotropes': '0.180', 'Thyrotropes': '0.496', 'Undifferentiated cells (Pituitary gland)': '-0.108', 'Mitotic cells (Spleen)': '-0.228', 'Platelets': '-0.050', 'Erythrocytes': '-0.158', 'Hematopoietic stem cells': '-0.211', 'B-cells (Spleen)': '0.266', 'NK-cells (Spleen)': '0.309', 'Amygdala excitatory': '1.0', 'Cerebellar inhibitory': '0.9', 'Cge interneuron': '0.7', 'Deep-layer corticothalamic and 6b': '1.5', 'Deep-layer intratelencephalic': '0.7', 'Deep-layer near-projecting': '0.7', 'Eccentric medium spiny neuron': '0.6', 'Hippocampal ca1-3': '1.9', 'Hippocampal ca4': '1.2', 'Hippocampal dentate gyrus': '1.1', 'Lamp5-lhx6 and chandelier': '0.5', 'Lower rhombic lip': '0.8', 'Mammillary body': '0.6', 'Medium spiny neuron': '0.7', 'Mge interneuron': '1.7', 'Midbrain-derived inhibitory': '0.7', 'Miscellaneous': '0.9', 'Splatter': '3.8', 'Thalamic excitatory': '0.5', 'Upper rhombic lip': '0.8', 'Upper-layer intratelencephalic': '0.6', 'Astrocyte': '4.4', 'Bergmann glia': '0.2', 'Central nervous system macrophage': '0.6', 'Choroid plexus epithelial cell': '52.1', 'Committed oligodendrocyte precursor': '41.5', 'Ependymal cell': '4.8', 'Oligodendrocyte': '53.1', 'Oligodendrocyte precursor cell': '2.4', 'Endothelial cell': '0.7', 'Pericyte': '0.3', 'Vascular associated smooth muscle cell': '0.0', 'Fibroblast': '17.4', 'Leukocyte': '1.1', 'Basophil': '0.0', 'Eosinophil': '0.0', 'Neutrophil': '0.0', 'Classical monocyte': '0.0', 'Non-classical monocyte': '0.0', 'Intermediate monocyte': '0.0', 'T-reg': '2.3', 'GdT-cell': '0.0', 'MAIT T-cell': '0.0', 'Memory CD4 T-cell': '0.0', 'Naive CD4 T-cell': '0.1', 'Memory CD8 T-cell': '0.2', 'Naive CD8 T-cell': '0.3', 'Memory B-cell': '0.0', 'Naive B-cell': '0.1', 'Plasmacytoid DC': '46.6', 'Myeloid DC': '8.5', 'NK-cell': '0.1', 'Total PBMC': '0.7', 'Vd2 gdTCR': '0.0', 'Memory CD4 T-cell Th1\\/Th17': '0.1', 'Memory CD4 T-cell Th17': '0.2', 'Memory CD4 T-cell Th2': '2.9', 'Non-Vd2 gdTCR': '0.1', 'Memory CD4 T-cell Th1': '0.3', 'Memory CD4 T-cell TFH': '0.5', 'Terminal effector memory CD4 T-cell': '0.0', 'Central memory CD8 T-cell': '4.8', 'Effector memory CD8 T-cell': '0.0', 'Terminal effector memory CD8 T-cell': '0.6', 'Non-switched memory B-cell': '0.0', 'Plasmablast': '3.3', 'Switched memory B-cell': '0.0', 'Exhausted memory B-cell': '0.7', 'Progenitor cell': '2.3', 'Memory T-reg': '1.3', 'Naive CD4 T-cell activated': '0.3', 'Naive CD8 T-cell activated': '0.6', 'Naive T-reg': '0.1'}
1O6S, 2O72, 2OMT, 2OMU, 2OMV, 2OMX, 2OMY, 2OMZ, 3FF7, 3FF8, 3L6X, 3L6Y, 4ZT1, 4ZTE, 6CXY, 6OLE, 6OLF, 6OLG, 6VEL, 7STZ, 8H62
{'Adipose Tissue': 1.2125261088039867, 'Adrenal Gland': 0.1914223992248062, 'Bladder': 39.2033519047619, 'Blood': 1.340954264800861, 'Blood Vessel': 0.3121561692883895, 'Brain': 0.8550442199091597, 'Breast': 38.54918344226579, 'Cervix Uteri': 23.539115789473684, 'Colon': 43.41292142490372, 'Esophagus': 53.97513367404844, 'Fallopian Tube': 14.900277777777776, 'Heart': 0.119140469221835, 'Kidney': 25.040449438202245, 'Liver': 26.60802654867257, 'Lung': 35.447986366782004, 'Muscle': 0.1378936151930261, 'Nerve': 17.518468982229404, 'Ovary': 3.6515122222222223, 'Pancreas': 56.89676829268293, 'Pituitary': 24.68741660777385, 'Prostate': 61.279967346938776, 'Salivary Gland': 92.01685185185184, 'Skin': 79.77571720232172, 'Small Intestine': 71.7519320855615, 'Spleen': 10.061029045643156, 'Stomach': 58.07813805013927, 'Testis': 0.8144204986149585, 'Thyroid': 135.176797856049, 'Uterus': 1.442593943661972, 'Vagina': 86.52345512820513}
CDCA3
MGSAKSVPVTPARPPPHNKHLARVADPRSPSAGILRTPIQVESSPQPGLPAGEQLEGLKHAQDSDPRSPTLGIARTPMKTSSGDPPSPLVKQLSEVFETEDSKSNLPPEPVLPPEAPLSSELDLPLGTQLSVEEQMPPWNQTEFPSKQVFSKEEARQPTETPVASQSSDKPSRDPETPRSSGSMRNRWKPNSSKVLGRSPLTILQDDNSPGTLTLRQGKRPSPLSENVSELKEGAILGTGRLLKTGGRAWEQGQDHDKENQHFPLVES
Homo sapiens
Cytoplasm, cytosol
Tissue enhanced (lymphoid tissue, retina)
{'Ciliated cells': '1.1', 'Basal respiratory cells': '5.2', 'Club cells': '1.5', 'Ionocytes': '1.5', 'Mucus glandular cells': '0.7', 'Serous glandular cells': '4.6', 'Gastric mucus-secreting cells': '4.7', 'Proximal enterocytes': '67.7', 'Paneth cells': '2.5', 'Distal enterocytes': '3.7', 'Intestinal goblet cells': '10.6', 'Exocrine glandular cells': '-0.301', 'Basal prostatic cells': '0.3', 'Prostatic glandular cells': '0.5', 'Breast glandular cells': '0.567', 'Breast myoepithelial cells': '0.513', 'Glandular and luminal cells': '2.4', 'Secretory cells': '0.3', 'Basal keratinocytes': '6.7', 'Suprabasal keratinocytes': '2.9', 'Basal squamous epithelial cells': '2.9', 'Squamous epithelial cells': '11.5', 'Alveolar cells type 1': '-0.296', 'Alveolar cells type 2': '-0.321', 'Salivary duct cells': '1.4', 'Ductal cells': '0.347', 'Hepatocytes': '0.223', 'Cholangiocytes': '1.9', 'Proximal tubular cells': '0.071', 'Distal tubular cells': '0.0', 'Collecting duct cells': '0.0', 'Mesothelial cells': '0.298', 'Sertoli cells': '-0.391', 'Granulosa cells': '3.1', 'Enteroendocrine cells': '1.5', 'Pancreatic endocrine cells': '3.4', 'Leydig cells': '-0.491', 'Excitatory neurons': '0.5', 'Inhibitory neurons': '0.6', 'Cone photoreceptor cells': '28.9', 'Rod photoreceptor cells': '25.5', 'Bipolar cells': '16.8', 'Horizontal cells': '1.9', 'Astrocytes': '0.6', 'Oligodendrocyte precursor cells': '0.5', 'Oligodendrocytes': '0.5', 'Microglial cells': '0.9', 'Muller glia cells': '1.5', 'Schwann cells': '0.180', 'Spermatogonia': '-0.216', 'Spermatocytes': '0.315', 'Early spermatids': '0.723', 'Late spermatids': '0.468', 'Oocytes': '9.6', 'Cytotrophoblasts': '32.3', 'Syncytiotrophoblasts': '10.8', 'Extravillous trophoblasts': '80.4', 'Endothelial cells': '1.5', 'Lymphatic endothelial cells': '0.0', 'Cardiomyocytes': '0.401', 'Skeletal myocytes': '-0.027', 'Smooth muscle cells': '1.6', 'Adipocytes': '0.5', 'Melanocytes': '0.321', 'Fibroblasts': '3.6', 'Peritubular cells': '-0.324', 'Endometrial stromal cells': '1.4', 'Ovarian stromal cells': '0.4', 'Undifferentiated cells': '31.6', 'T-cells': '2.9', 'B-cells': '0.9', 'Plasma cells': '20.7', 'Nk-cells': '0.9', 'Granulocytes': '0.0', 'Monocytes': '0.0', 'Macrophages': '2.8', 'Hofbauer cells': '15.3', 'Kupffer cells': '2.4', 'Dendritic cells': '0.0', 'Langerhans cells': '0.167', 'Erythroid cells': '0.095', 'Adipocytes (Subcutaneous)': '-0.417', 'Adipocytes (Visceral)': '-0.398', 'Breast glandular cells (progenitors)': '0.440', 'Adipocytes (Breast)': '-0.525', 'Colon enterocytes': '-0.009', 'Colon enteroendocrine cells': '0.020', 'Enteric glia cells': '0.421', 'Mitotic cells (Colon)': '0.107', 'Mitotic cells (Heart)': '0.407', 'Podocytes': '-0.213', 'Ascending Loop of Henle cells': '0.436', 'Intercalated cells': '-0.126', 'Cholangiocyte': '0.223', 'NK-cells (Liver)': '0.012', 'Respiratory ciliated cells': '0.132', 'Mitotic cells (Lung)': '0.575', 'NK-cells (Lung)': '0.073', 'B-cells (Lung)': '0.182', 'Alpha cells': '0.315', 'Beta cells': '0.159', 'Prostate glandular cells': '-0.209', 'Prostate basal glandular cells': '0.064', 'Urothelial cells': '0.152', 'Keratinocyte (other)': '0.114', 'Keratinocyte (granular)': '-0.254', 'Hair cortex cells': '0.099', 'Inner root sheath cells': '0.194', 'Outer root sheath cells': '0.326', 'Sebaceous gland cells': '0.068', 'Eccrine sweat gland cells': '-0.019', 'Adipocytes (Skin)': '-0.109', 'Mitotic cells (Skin)': '0.729', 'Parietal cells': '-0.353', 'Chief cells': '-0.256', 'Gastric mucous cells': '0.134', 'Gastric enteroendocrine cells': '-0.048', 'Mitotic cells (Stomach)': '0.598', 'Parafollicular cells': '0.027', 'Thyroid glandular cells': '-0.096', 'Mitotic cells (Thyroid)': '0.184', 'Adrenal cortex cells': '0.131', 'Adrenal medulla cells': '0.159', 'Mitotic cells (Adrenal gland)': '0.397', 'Minor salivary glandular cells': '0.060', 'Minor salivary gland ductal cells': '-0.112', 'Minor salivary gland basal cells': '0.353', 'Mitotic cells (Minor salivary gland)': '0.486', 'Adipocytes (Minor salivary gland)': '-0.002', 'Somatotropes': '0.221', 'Lactotropes': '0.336', 'Gonadotropes': '0.147', 'Corticotropes': '0.148', 'Thyrotropes': '0.192', 'Undifferentiated cells (Pituitary gland)': '-0.215', 'Mitotic cells (Spleen)': '0.880', 'Platelets': '0.049', 'Erythrocytes': '0.381', 'Hematopoietic stem cells': '0.281', 'B-cells (Spleen)': '-0.107', 'NK-cells (Spleen)': '-0.166', 'Amygdala excitatory': '0.6', 'Cerebellar inhibitory': '1.5', 'Cge interneuron': '0.9', 'Deep-layer corticothalamic and 6b': '0.7', 'Deep-layer intratelencephalic': '0.9', 'Deep-layer near-projecting': '1.1', 'Eccentric medium spiny neuron': '0.8', 'Hippocampal ca1-3': '0.8', 'Hippocampal ca4': '0.5', 'Hippocampal dentate gyrus': '0.8', 'Lamp5-lhx6 and chandelier': '1.2', 'Lower rhombic lip': '1.1', 'Mammillary body': '1.2', 'Medium spiny neuron': '1.0', 'Mge interneuron': '1.0', 'Midbrain-derived inhibitory': '1.1', 'Miscellaneous': '0.6', 'Splatter': '0.9', 'Thalamic excitatory': '1.2', 'Upper rhombic lip': '1.5', 'Upper-layer intratelencephalic': '1.2', 'Astrocyte': '1.1', 'Bergmann glia': '1.3', 'Central nervous system macrophage': '0.4', 'Choroid plexus epithelial cell': '0.2', 'Committed oligodendrocyte precursor': '1.1', 'Ependymal cell': '0.6', 'Oligodendrocyte': '0.7', 'Oligodendrocyte precursor cell': '0.9', 'Endothelial cell': '0.1', 'Pericyte': '0.7', 'Vascular associated smooth muscle cell': '2.2', 'Fibroblast': '0.3', 'Leukocyte': '0.6', 'Basophil': '0.5', 'Eosinophil': '0.0', 'Neutrophil': '0.0', 'Classical monocyte': '0.4', 'Non-classical monocyte': '0.4', 'Intermediate monocyte': '0.8', 'T-reg': '1.6', 'GdT-cell': '0.1', 'MAIT T-cell': '1.1', 'Memory CD4 T-cell': '0.7', 'Naive CD4 T-cell': '1.4', 'Memory CD8 T-cell': '0.8', 'Naive CD8 T-cell': '1.5', 'Memory B-cell': '0.7', 'Naive B-cell': '0.5', 'Plasmacytoid DC': '5.0', 'Myeloid DC': '1.2', 'NK-cell': '1.3', 'Total PBMC': '1.9', 'Vd2 gdTCR': '0.4', 'Memory CD4 T-cell Th1\\/Th17': '0.9', 'Memory CD4 T-cell Th17': '0.7', 'Memory CD4 T-cell Th2': '0.8', 'Non-Vd2 gdTCR': '0.6', 'Memory CD4 T-cell Th1': '1.2', 'Memory CD4 T-cell TFH': '0.8', 'Terminal effector memory CD4 T-cell': '0.6', 'Central memory CD8 T-cell': '1.6', 'Effector memory CD8 T-cell': '3.1', 'Terminal effector memory CD8 T-cell': '0.9', 'Non-switched memory B-cell': '1.3', 'Plasmablast': '17.1', 'Switched memory B-cell': '2.1', 'Exhausted memory B-cell': '1.8', 'Progenitor cell': '0.6', 'Memory T-reg': '1.5', 'Naive CD4 T-cell activated': '0.6', 'Naive CD8 T-cell activated': '0.7', 'Naive T-reg': '1.6'}
null
{'Adipose Tissue': 1.697385880398671, 'Adrenal Gland': 2.2178387596899225, 'Bladder': 3.365333333333333, 'Blood': 6.0672309041980625, 'Blood Vessel': 3.441423146067416, 'Brain': 3.8342124034822103, 'Breast': 2.094447494553377, 'Cervix Uteri': 6.3098947368421054, 'Colon': 3.588561103979461, 'Esophagus': 4.371234117647059, 'Fallopian Tube': 3.478666666666667, 'Heart': 1.681350487804878, 'Kidney': 1.3614191011235957, 'Liver': 0.761991017699115, 'Lung': 3.2482290657439448, 'Muscle': 0.3367464508094645, 'Nerve': 3.3772174474959615, 'Ovary': 7.074755555555555, 'Pancreas': 0.6857734756097561, 'Pituitary': 11.611904593639576, 'Prostate': 5.338008163265306, 'Salivary Gland': 3.0030895061728393, 'Skin': 6.547355389718076, 'Small Intestine': 8.526960962566845, 'Spleen': 5.392302904564316, 'Stomach': 2.8459551532033425, 'Testis': 28.469642659279778, 'Thyroid': 3.876059571209801, 'Uterus': 6.873133802816901, 'Vagina': 6.000673076923077}
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0.32, 0.01, 0.22, 0.0, 0.05, 0.0, 0.41, 0.46, 0.42, 0.82, 0.48, 0.4, 0.5, 0.17, 0.62, 0.06, 0.32, 0.0, 0.25, 0.0, 0.42, 0.08, 0.41, 0.27, 0.16, 0.04, 0.36, 0.32, 0.2, 0.0, 0.52, 0.04, 0.66, 0.47, 0.52, 0.78, 0.09, 0.77, 0.08, 0.6, 0.0, 0.31, 0.03, 0.58, 0.47, 0.59, 0.44, 0.23, 0.54, 0.1, 0.18, 0.45, 0.0, 0.53, 0.11, 0.59, 0.17, 0.51, 0.01, 0.19, 0.71, 0.77, 0.3, 0.44, 0.08, 0.14, 0.52, 0.05, 0.37, 0.1, 0.42, 0.23, 0.61, 0.43, 0.22, 0.96, 0.54, 0.4, 0.3, 0.07, 0.39, 0.17, 0.43, 0.38, 0.3, 0.8, 0.83, 0.44, 0.03, 0.11, 0.0, 0.23, 0.0, 0.31, 0.0, 0.38, 0.58, 0.51, 0.01, 0.49, 0.13, 0.26, 0.69, 0.46, 0.41, 0.51, 0.06, 0.51, 0.03, 0.38, 0.0, 0.06, 0.0, 0.34, 0.08, 0.53, 0.42, 0.88, 0.25, 0.75, 0.49, 1.0, 0.34, 0.86, 0.48, 0.18, 0.52, 0.01, 0.32, 0.0, 0.19, 0.0, 0.3, 0.05, 0.44, 0.27, 0.43, 0.11, 0.31, 0.39, 0.03, 0.55, 0.04, 0.52, 0.51, 0.64, 0.57, 0.19, 0.68, 0.13, 0.84, 0.06, 0.31, 0.07, 0.69, 0.26, 0.37, 0.53, 0.67, 0.5, 0.56, 0.14, 0.18, 0.47, 0.01, 0.47, 0.15, 0.61, 0.28, 0.2, 0.02, 0.76, 0.55, 0.31, 0.94, 0.22, 0.57, 0.17, 0.4, 0.07, 0.5, 0.31, 0.7, 0.2, 0.14, 0.3, 0.23, 0.58, 0.07, 0.06, 0.55, 0.15, 0.46, 0.43, 0.64, 0.53, 0.0, 0.18, 0.01, 0.23, 0.02, 0.63, 0.33, 0.79, 0.06, 0.38, 0.07, 0.14, 0.23, 0.68, 0.89, 0.29, 0.06, 0.72, 0.92, 0.24, 0.25, 0.0, 0.46, 0.02, 0.21, 0.01, 0.06, 0.0, 0.05, 0.07, 0.61, 0.17, 0.89, 0.72, 0.66, 0.14, 0.52, 0.07, 0.58, 0.01, 0.26, 0.0, 0.13, 0.0, 0.29, 0.04, 0.46, 0.27, 0.28, 0.23, 0.56, 0.32, 0.25, 0.0, 0.33, 0.05, 0.55, 0.5, 0.58, 0.53, 0.04, 0.27, 0.02, 0.04, 0.37, 0.67, 0.74, 0.35, 0.62, 0.54, 0.26, 0.46, 0.0, 0.47, 0.09, 0.45, 0.15, 0.39, 0.05, 0.44, 0.85, 0.56, 0.11, 0.11, 0.35, 0.42, 0.03, 0.32, 0.12, 0.49, 0.19, 0.25, 0.8, 0.6, 0.09, 0.49, 0.57, 0.36, 0.04, 0.35, 0.28, 0.52, 0.39, 0.5, 0.28, 0.93, 0.47, 0.3, 0.47, 0.08, 0.02, 0.18, 0.01, 0.34, 0.23, 0.55, 0.57, 0.91, 0.1, 0.78, 0.52, 0.34, 0.61, 0.24, 0.75, 0.0, 0.2, 0.02, 0.24, 0.0, 0.18, 0.04, 0.44, 0.59, 0.71, 0.29, 0.52, 0.37, 0.5, 0.11, 0.6, 0.02, 0.48, 0.01, 0.16, 0.04, 0.35, 0.66, 0.47, 0.74, 0.14, 0.62, 0.16, 0.77, 0.79, 0.27, 0.93, 0.69, 0.88, 0.88, 0.85, 0.87, 0.91, 0.92, 0.82, 0.63, 0.75, 0.7, 0.7, 0.38, 0.43, 0.64, 0.55, 0.54, 0.59, 0.45, 0.47, 0.5, 0.58, 0.52, 0.61, 0.57, 0.52, 0.68, 0.44, 0.6, 0.61, 0.58, 0.55, 0.5, 0.61, 0.61, 0.86, 0.86, 0.75, 0.91, 0.96, 0.93, 1.0, 0.87, 0.97, 0.91, 0.95, 0.86, 0.98, 0.93, 0.88, 0.59, 0.87, 0.7, 0.67, 0.85, 0.89, 0.88, 0.91, 0.93, 0.88, 0.99, 0.92, 1.0, 0.79, 0.9, 1.0, 0.94, 1.0, 0.97, 0.96, 0.9, 0.63, 0.68, 0.48, 0.54, 0.8, 0.7, 0.7, 0.95, 0.87, 0.77, 0.84, 0.79, 0.89, 0.95, 0.8, 0.77, 0.51, 0.87, 0.7, 0.52, 0.84, 0.91, 0.51, 0.96, 0.79, 0.92, 0.84, 0.21, 0.89, 0.53, 0.52, 0.89, 0.86, 0.26, 0.91, 0.45, 0.68, 0.84, 0.48, 0.44, 0.51, 0.62, 0.28, 0.59, 0.63, 0.57, 0.15, 0.55, 0.66, 0.1, 0.38, 0.74, 0.65, 0.17, 0.43, 0.66, 0.41, 0.8, 0.75, 0.9, 0.93, 0.52, 0.76, 0.89, 0.87, 0.76, 0.92, 0.91, 0.75, 0.61, 0.96, 0.89, 0.73, 0.97, 0.68, 0.87, 0.55, 0.85, 0.77, 0.69, 0.76, 0.98, 0.83, 0.68, 0.82, 0.74, 0.65, 0.96, 0.93, 0.54, 0.64, 0.28, 0.54, 0.52, 0.16, 0.51, 0.88, 0.6, 0.4, 0.88, 0.95, 0.33, 0.56, 0.73, 0.39, 0.06, 0.61, 0.75, 0.47, 0.19, 0.87, 0.7, 0.97, 0.94, 0.97]
[53.88, 53.29, 62.02, 68.33, 69.85, 74.94, 72.63, 68.91, 69.48, 69.18, 64.05, 71.87, 74.74, 74.82, 73.63, 73.04, 75.29, 73.93, 81.52, 77.2, 75.08, 72.82, 71.81, 75.24, 72.9, 77.28, 72.77, 72.71, 68.44, 70.64, 69.79, 63.9, 66.38, 69.58, 72.43, 71.5, 79.97, 79.9, 72.6, 78.7, 75.05, 72.41, 58.57, 68.87, 67.2, 66.34, 58.02, 44.39, 56.46, 48.37, 45.23, 40.1, 45.69, 44.61, 43.82, 40.06, 38.74, 50.89, 43.07, 53.27, 51.98, 57.36, 58.65, 62.67, 77.8, 76.13, 76.54, 75.01, 78.52, 77.89, 75.56, 75.47, 76.79, 76.16, 80.68, 79.03, 79.58, 80.59, 80.79, 72.06, 65.47, 62.2, 69.56, 71.48, 78.97, 78.47, 81.77, 85.66, 88.18, 87.09, 86.09, 88.55, 89.01, 85.64, 85.95, 82.35, 81.26, 74.69, 62.8, 61.3, 57.57, 54.16, 46.85, 46.28, 37.91, 49.98, 53.81, 52.74, 44.41, 50.53, 46.45, 46.69, 54.42, 51.02, 40.51, 45.6, 41.5, 37.96, 42.32, 50.2, 44.62, 48.76, 44.51, 52.23, 46.62, 48.92, 43.87, 49.74, 42.75, 50.43, 42.95, 52.65, 44.64, 41.15, 45.26, 44.3, 61.81, 40.8, 44.45, 50.89, 38.46, 46.09, 49.81, 44.21, 48.05, 46.93, 50.99, 48.8, 44.97, 48.25, 59.49, 52.02, 56.72, 42.77, 46.09, 46.18, 40.11, 45.39, 41.14, 48.11, 47.55, 52.59, 55.94, 48.67, 46.45, 55.02, 48.48, 51.64, 56.82, 55.28, 50.28, 56.05, 48.96, 46.3, 51.74, 56.19, 53.76, 55.49, 46.51, 46.04, 46.64, 46.17, 56.17, 55.94, 46.02, 55.17, 47.29, 52.63, 59.28, 56.66, 52.2, 49.55, 43.55, 54.42, 55.0, 60.58, 65.81, 71.48, 74.3, 75.11, 74.08, 67.23, 66.18, 71.01, 68.39, 67.31, 68.67, 68.7, 58.64, 59.04, 56.02, 52.65, 54.78, 57.51, 57.97, 56.9, 60.17, 56.23, 58.43, 59.56, 61.17, 57.68, 59.59, 62.55, 65.77, 67.76, 49.25, 62.01, 60.43, 48.29, 57.24, 57.12, 51.72, 46.87, 40.78, 54.92, 53.4, 49.96, 48.06, 44.03, 51.2, 46.16, 58.1, 47.96, 53.82, 38.75, 38.07, 48.9, 41.41, 51.94, 49.36, 43.24, 48.37, 48.91, 57.04, 58.66, 60.69, 71.4, 71.04, 61.9, 64.67, 65.82, 64.2, 70.36, 68.57, 62.2, 60.72, 52.16]
[1.0, 1.0, 0.89, 0.95, 0.91, 0.88, 0.82, 0.84, 0.86, 0.84, 0.86, 0.87, 0.94, 0.91, 0.87, 0.92, 0.75, 0.46, 0.77, 0.77, 0.61, 0.63, 0.9, 0.61, 0.84, 0.49, 0.89, 0.91, 0.52, 0.85, 0.48, 0.93, 0.88, 0.54, 0.94, 0.69, 0.88, 0.89, 0.8, 0.84, 0.64, 0.88, 0.83, 0.82, 0.9, 0.88, 0.89, 0.88, 0.92, 0.97, 0.98, 0.94, 0.99, 0.99, 0.99, 0.98, 1.0, 0.94, 1.0, 0.73, 0.98, 0.77, 0.87, 0.91, 0.5, 0.89, 0.91, 0.51, 0.86, 0.62, 0.9, 0.92, 0.64, 0.9, 0.89, 0.93, 0.89, 0.89, 0.96, 0.77, 0.73, 0.84, 0.92, 0.79, 0.92, 0.55, 0.48, 0.75, 0.64, 0.45, 0.57, 0.63, 0.45, 0.38, 0.64, 0.62, 0.63, 0.62, 0.7, 0.8, 0.76, 0.73, 0.84, 0.66, 0.89, 0.87, 0.92, 0.91, 0.87, 0.84, 0.9, 0.94, 0.93, 0.92, 0.99, 0.91, 0.87, 0.99, 0.82, 0.98, 0.98, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 0.98, 1.0, 0.98, 0.99, 1.0, 0.88, 0.99, 0.85, 0.98, 0.95, 0.87, 0.96, 0.89, 1.0, 0.92, 0.99, 0.98, 0.98, 0.96, 0.98, 0.85, 0.92, 0.86, 0.93, 0.91, 0.97, 0.87, 0.99, 0.97, 0.99, 0.99, 0.92, 1.0, 0.98, 1.0, 1.0, 0.99, 1.0, 0.99, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 0.99, 0.98, 0.98, 0.95, 0.96, 0.95, 0.98, 0.99, 0.93, 0.94, 0.92, 0.94, 0.85, 0.94, 0.8, 0.89, 0.99, 0.9, 0.99, 0.91, 0.93, 0.67, 0.52, 0.75, 0.7, 0.34, 0.52, 0.67, 0.71, 0.43, 0.77, 0.75, 0.68, 0.96, 0.83, 0.86, 0.96, 0.69, 0.87, 0.88, 0.91, 0.91, 0.96, 0.97, 0.9, 0.88, 0.9, 0.95, 0.79, 0.87, 0.91, 0.81, 0.94, 0.97, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 0.96, 1.0, 0.96, 0.95, 0.9, 0.87, 0.92, 0.89, 0.99, 1.0, 0.9, 0.98, 0.89, 0.96, 0.95, 0.76, 0.72, 0.9, 0.6, 0.72, 0.77, 0.86, 0.78, 0.86, 0.85, 0.93, 0.92, 0.77, 0.92, 0.81, 0.98]
null
Component of an E-cadherin/ catenin adhesion complex composed of at least E-cadherin/CDH1, beta-catenin/CTNNB1 or gamma-catenin/JUP, and potentially alpha-catenin/CTNNA1. Forms a ternary complex composed of ADAM10, CADH1 and EPHA4,
null
null
KLRG1, SPEF1, DLGAP5, AJAP1, RAPGEF2, RAB8B, PIP5K1C, PKP2, TRPV4, CTNNB1, CAV1, DDR1, TBC1D2, CTNNA1, JUP, CTNND1, PSEN1, LIMA1, CDH1, JUP, ADAM10, CADH1 , EPHA4,
null
null
null
null
Homodimer
null
79.91949
0.474025
59.097799
0.865634
2,497
P12830
Q99728
null
degron_data
CDH1
MGPWSRSLSALLLLLQVSSWLCQEPEPCHPGFDAESYTFTVPRRHLERGRVLGRVNFEDCTGRQRTAYFSLDTRFKVGTDGVITVKRPLRFHNPQIHFLVYAWDSTYRKFSTKVTLNTVGHHHRPPPHQASVSGIQAELLTFPNSSPGLRRQKRDWVIPPISCPENEKGPFPKNLVQIKSNKDKEGKVFYSITGQGADTPPVGVFIIERETGWLKVTEPLDRERIATYTLFSHAVSSNGNAVEDPMEILITVTDQNDNKPEFTQEVFKGSVMEGALPGTSVMEVTATDADDDVNTYNAAIAYTILSQDPELPDKNMFTINRNTGVISVVTTGLDRESFPTYTLVVQAADLQGEGLSTTATAVITVTDTNDNPPIFNPTTYKGQVPENEANVVITTLKVTDADAPNTPAWEAVYTILNDDGGQFVVTTNPVNNDGILKTAKGLDFEAKQQYILHVAVTNVVPFEVSLTTSTATVTVDVLDVNEAPIFVPPEKRVEVSEDFGVGQEITSYTAQEPDTFMEQKITYRIWRDTANWLEINPDTGAISTRAELDREDFEHVKNSTYTALIIATDNGSPVATGTGTLLLILSDVNDNAPIPEPRTIFFCERNPKPQVINIIDADLPPNTSPFTAELTHGASANWTIQYNDPTQESIILKPKMALEVGDYKINLKLMDNQNKDQVTTLEVSVCDCEGAAGVCRKAQPVEAGLQIPAILGILGGILALLILILLLLLFLRRRAVVKEPLLPPEDDTRDNVYYYDEEGGGEEDQDFDLSQLHRGLDARPEVTRNDVAPTLMSVPRYLPRPANPDEIGNFIDENLKAADTDPTAPPYDSLLVFDYEGSGSEAASLSSLNSSESDKDQDYDYLNEWGNRFKKLADMYGGGEDD
Homo sapiens
Cell junction, adherens junction, Cell membrane, Endosome, Golgi apparatus, trans-Golgi network, Cytoplasm, Cell junction, desmosome
Tissue enhanced (parathyroid)
{'Ciliated cells': '119.1', 'Basal respiratory cells': '71.1', 'Club cells': '97.3', 'Ionocytes': '81.0', 'Mucus glandular cells': '155.0', 'Serous glandular cells': '67.8', 'Gastric mucus-secreting cells': '133.2', 'Proximal enterocytes': '140.9', 'Paneth cells': '125.1', 'Distal enterocytes': '307.5', 'Intestinal goblet cells': '173.5', 'Exocrine glandular cells': '-0.605', 'Basal prostatic cells': '68.3', 'Prostatic glandular cells': '186.7', 'Breast glandular cells': '0.773', 'Breast myoepithelial cells': '0.700', 'Glandular and luminal cells': '313.0', 'Secretory cells': '82.3', 'Basal keratinocytes': '102.5', 'Suprabasal keratinocytes': '162.6', 'Basal squamous epithelial cells': '51.0', 'Squamous epithelial cells': '106.9', 'Alveolar cells type 1': '0.437', 'Alveolar cells type 2': '0.706', 'Salivary duct cells': '95.9', 'Ductal cells': '0.541', 'Hepatocytes': '0.600', 'Cholangiocytes': '129.7', 'Proximal tubular cells': '0.042', 'Distal tubular cells': '0.0', 'Collecting duct cells': '143.9', 'Mesothelial cells': '0.799', 'Sertoli cells': '0.252', 'Granulosa cells': '12.9', 'Enteroendocrine cells': '92.4', 'Pancreatic endocrine cells': '78.1', 'Leydig cells': '0.264', 'Excitatory neurons': '0.7', 'Inhibitory neurons': '1.3', 'Cone photoreceptor cells': '0.0', 'Rod photoreceptor cells': '0.0', 'Bipolar cells': '0.2', 'Horizontal cells': '0.6', 'Astrocytes': '0.6', 'Oligodendrocyte precursor cells': '0.5', 'Oligodendrocytes': '29.9', 'Microglial cells': '0.9', 'Muller glia cells': '0.1', 'Schwann cells': '0.131', 'Spermatogonia': '0.392', 'Spermatocytes': '0.193', 'Early spermatids': '-0.217', 'Late spermatids': '-0.290', 'Oocytes': '16.9', 'Cytotrophoblasts': '119.2', 'Syncytiotrophoblasts': '45.0', 'Extravillous trophoblasts': '24.9', 'Endothelial cells': '6.1', 'Lymphatic endothelial cells': '0.4', 'Cardiomyocytes': '0.135', 'Skeletal myocytes': '0.107', 'Smooth muscle cells': '5.8', 'Adipocytes': '2.1', 'Melanocytes': '0.335', 'Fibroblasts': '6.5', 'Peritubular cells': '0.210', 'Endometrial stromal cells': '27.7', 'Ovarian stromal cells': '0.7', 'Undifferentiated cells': '101.6', 'T-cells': '2.9', 'B-cells': '4.4', 'Plasma cells': '6.1', 'Nk-cells': '0.0', 'Granulocytes': '8.4', 'Monocytes': '0.0', 'Macrophages': '6.0', 'Hofbauer cells': '4.3', 'Kupffer cells': '1.0', 'Dendritic cells': '5.9', 'Langerhans cells': '0.304', 'Erythroid cells': '0.036', 'Adipocytes (Subcutaneous)': '-0.081', 'Adipocytes (Visceral)': '-0.209', 'Breast glandular cells (progenitors)': '0.538', 'Adipocytes (Breast)': '-0.689', 'Colon enterocytes': '0.790', 'Colon enteroendocrine cells': '0.112', 'Enteric glia cells': '-0.048', 'Mitotic cells (Colon)': '0.299', 'Mitotic cells (Heart)': '0.120', 'Podocytes': '-0.118', 'Ascending Loop of Henle cells': '0.475', 'Intercalated cells': '0.212', 'Cholangiocyte': '0.090', 'NK-cells (Liver)': '-0.005', 'Respiratory ciliated cells': '-0.012', 'Mitotic cells (Lung)': '0.071', 'NK-cells (Lung)': '-0.266', 'B-cells (Lung)': '-0.296', 'Alpha cells': '0.270', 'Beta cells': '0.152', 'Prostate glandular cells': '0.764', 'Prostate basal glandular cells': '0.540', 'Urothelial cells': '0.205', 'Keratinocyte (other)': '0.510', 'Keratinocyte (granular)': '0.055', 'Hair cortex cells': '0.080', 'Inner root sheath cells': '0.131', 'Outer root sheath cells': '0.175', 'Sebaceous gland cells': '0.156', 'Eccrine sweat gland cells': '-0.207', 'Adipocytes (Skin)': '-0.244', 'Mitotic cells (Skin)': '0.442', 'Parietal cells': '0.654', 'Chief cells': '0.649', 'Gastric mucous cells': '0.781', 'Gastric enteroendocrine cells': '0.590', 'Mitotic cells (Stomach)': '0.445', 'Parafollicular cells': '0.173', 'Thyroid glandular cells': '0.865', 'Mitotic cells (Thyroid)': '-0.081', 'Adrenal cortex cells': '0.051', 'Adrenal medulla cells': '0.087', 'Mitotic cells (Adrenal gland)': '0.072', 'Minor salivary glandular cells': '0.371', 'Minor salivary gland ductal cells': '-0.142', 'Minor salivary gland basal cells': '0.582', 'Mitotic cells (Minor salivary gland)': '0.567', 'Adipocytes (Minor salivary gland)': '0.050', 'Somatotropes': '0.121', 'Lactotropes': '0.322', 'Gonadotropes': '0.330', 'Corticotropes': '0.180', 'Thyrotropes': '0.496', 'Undifferentiated cells (Pituitary gland)': '-0.108', 'Mitotic cells (Spleen)': '-0.228', 'Platelets': '-0.050', 'Erythrocytes': '-0.158', 'Hematopoietic stem cells': '-0.211', 'B-cells (Spleen)': '0.266', 'NK-cells (Spleen)': '0.309', 'Amygdala excitatory': '1.0', 'Cerebellar inhibitory': '0.9', 'Cge interneuron': '0.7', 'Deep-layer corticothalamic and 6b': '1.5', 'Deep-layer intratelencephalic': '0.7', 'Deep-layer near-projecting': '0.7', 'Eccentric medium spiny neuron': '0.6', 'Hippocampal ca1-3': '1.9', 'Hippocampal ca4': '1.2', 'Hippocampal dentate gyrus': '1.1', 'Lamp5-lhx6 and chandelier': '0.5', 'Lower rhombic lip': '0.8', 'Mammillary body': '0.6', 'Medium spiny neuron': '0.7', 'Mge interneuron': '1.7', 'Midbrain-derived inhibitory': '0.7', 'Miscellaneous': '0.9', 'Splatter': '3.8', 'Thalamic excitatory': '0.5', 'Upper rhombic lip': '0.8', 'Upper-layer intratelencephalic': '0.6', 'Astrocyte': '4.4', 'Bergmann glia': '0.2', 'Central nervous system macrophage': '0.6', 'Choroid plexus epithelial cell': '52.1', 'Committed oligodendrocyte precursor': '41.5', 'Ependymal cell': '4.8', 'Oligodendrocyte': '53.1', 'Oligodendrocyte precursor cell': '2.4', 'Endothelial cell': '0.7', 'Pericyte': '0.3', 'Vascular associated smooth muscle cell': '0.0', 'Fibroblast': '17.4', 'Leukocyte': '1.1', 'Basophil': '0.0', 'Eosinophil': '0.0', 'Neutrophil': '0.0', 'Classical monocyte': '0.0', 'Non-classical monocyte': '0.0', 'Intermediate monocyte': '0.0', 'T-reg': '2.3', 'GdT-cell': '0.0', 'MAIT T-cell': '0.0', 'Memory CD4 T-cell': '0.0', 'Naive CD4 T-cell': '0.1', 'Memory CD8 T-cell': '0.2', 'Naive CD8 T-cell': '0.3', 'Memory B-cell': '0.0', 'Naive B-cell': '0.1', 'Plasmacytoid DC': '46.6', 'Myeloid DC': '8.5', 'NK-cell': '0.1', 'Total PBMC': '0.7', 'Vd2 gdTCR': '0.0', 'Memory CD4 T-cell Th1\\/Th17': '0.1', 'Memory CD4 T-cell Th17': '0.2', 'Memory CD4 T-cell Th2': '2.9', 'Non-Vd2 gdTCR': '0.1', 'Memory CD4 T-cell Th1': '0.3', 'Memory CD4 T-cell TFH': '0.5', 'Terminal effector memory CD4 T-cell': '0.0', 'Central memory CD8 T-cell': '4.8', 'Effector memory CD8 T-cell': '0.0', 'Terminal effector memory CD8 T-cell': '0.6', 'Non-switched memory B-cell': '0.0', 'Plasmablast': '3.3', 'Switched memory B-cell': '0.0', 'Exhausted memory B-cell': '0.7', 'Progenitor cell': '2.3', 'Memory T-reg': '1.3', 'Naive CD4 T-cell activated': '0.3', 'Naive CD8 T-cell activated': '0.6', 'Naive T-reg': '0.1'}
1O6S, 2O72, 2OMT, 2OMU, 2OMV, 2OMX, 2OMY, 2OMZ, 3FF7, 3FF8, 3L6X, 3L6Y, 4ZT1, 4ZTE, 6CXY, 6OLE, 6OLF, 6OLG, 6VEL, 7STZ, 8H62
{'Adipose Tissue': 1.2125261088039867, 'Adrenal Gland': 0.1914223992248062, 'Bladder': 39.2033519047619, 'Blood': 1.340954264800861, 'Blood Vessel': 0.3121561692883895, 'Brain': 0.8550442199091597, 'Breast': 38.54918344226579, 'Cervix Uteri': 23.539115789473684, 'Colon': 43.41292142490372, 'Esophagus': 53.97513367404844, 'Fallopian Tube': 14.900277777777776, 'Heart': 0.119140469221835, 'Kidney': 25.040449438202245, 'Liver': 26.60802654867257, 'Lung': 35.447986366782004, 'Muscle': 0.1378936151930261, 'Nerve': 17.518468982229404, 'Ovary': 3.6515122222222223, 'Pancreas': 56.89676829268293, 'Pituitary': 24.68741660777385, 'Prostate': 61.279967346938776, 'Salivary Gland': 92.01685185185184, 'Skin': 79.77571720232172, 'Small Intestine': 71.7519320855615, 'Spleen': 10.061029045643156, 'Stomach': 58.07813805013927, 'Testis': 0.8144204986149585, 'Thyroid': 135.176797856049, 'Uterus': 1.442593943661972, 'Vagina': 86.52345512820513}
BARD1
MPDNRQPRNRQPRIRSGNEPRSAPAMEPDGRGAWAHSRAALDRLEKLLRCSRCTNILREPVCLGGCEHIFCSNCVSDCIGTGCPVCYTPAWIQDLKINRQLDSMIQLCSKLRNLLHDNELSDLKEDKPRKSLFNDAGNKKNSIKMWFSPRSKKVRYVVSKASVQTQPAIKKDASAQQDSYEFVSPSPPADVSERAKKASARSGKKQKKKTLAEINQKWNLEAEKEDGEFDSKEESKQKLVSFCSQPSVISSPQINGEIDLLASGSLTESECFGSLTEVSLPLAEQIESPDTKSRNEVVTPEKVCKNYLTSKKSLPLENNGKRGHHNRLSSPISKRCRTSILSTSGDFVKQTVPSENIPLPECSSPPSCKRKVGGTSGRKNSNMSDEFISLSPGTPPSTLSSSSYRRVMSSPSAMKLLPNMAVKRNHRGETLLHIASIKGDIPSVEYLLQNGSDPNVKDHAGWTPLHEACNHGHLKVVELLLQHKALVNTTGYQNDSPLHDAAKNGHVDIVKLLLSYGASRNAVNIFGLRPVDYTDDESMKSLLLLPEKNESSSASHCSVMNTGQRRDGPLVLIGSGLSSEQQKMLSELAVILKAKKYTEFDSTVTHVVVPGDAVQSTLKCMLGILNGCWILKFEWVKACLRRKVCEQEEKYEIPEGPRRSRLNREQLLPKLFDGCYFYLWGTFKHHPKDNLIKLVTAGGGQILSRKPKPDSDVTQTINTVAYHARPDSDQRFCTQYIIYEDLCNYHPERVRQGKVWKAPSSWFIDCVMSFELLPLDS
Homo sapiens
Nucleus
Low tissue specificity
{'Ciliated cells': '12.1', 'Basal respiratory cells': '12.3', 'Club cells': '17.4', 'Ionocytes': '14.0', 'Mucus glandular cells': '6.6', 'Serous glandular cells': '14.1', 'Gastric mucus-secreting cells': '9.4', 'Proximal enterocytes': '2.3', 'Paneth cells': '8.8', 'Distal enterocytes': '7.0', 'Intestinal goblet cells': '12.3', 'Exocrine glandular cells': '-0.572', 'Basal prostatic cells': '11.7', 'Prostatic glandular cells': '4.6', 'Breast glandular cells': '0.534', 'Breast myoepithelial cells': '0.671', 'Glandular and luminal cells': '17.1', 'Secretory cells': '20.8', 'Basal keratinocytes': '58.7', 'Suprabasal keratinocytes': '56.9', 'Basal squamous epithelial cells': '17.7', 'Squamous epithelial cells': '27.4', 'Alveolar cells type 1': '0.042', 'Alveolar cells type 2': '-0.188', 'Salivary duct cells': '13.1', 'Ductal cells': '0.690', 'Hepatocytes': '0.301', 'Cholangiocytes': '11.4', 'Proximal tubular cells': '-0.015', 'Distal tubular cells': '3.1', 'Collecting duct cells': '7.8', 'Mesothelial cells': '0.141', 'Sertoli cells': '0.284', 'Granulosa cells': '18.9', 'Enteroendocrine cells': '6.2', 'Pancreatic endocrine cells': '0.0', 'Leydig cells': '0.294', 'Excitatory neurons': '5.3', 'Inhibitory neurons': '14.8', 'Cone photoreceptor cells': '1.7', 'Rod photoreceptor cells': '6.8', 'Bipolar cells': '3.5', 'Horizontal cells': '4.4', 'Astrocytes': '13.9', 'Oligodendrocyte precursor cells': '18.4', 'Oligodendrocytes': '29.5', 'Microglial cells': '15.2', 'Muller glia cells': '3.7', 'Schwann cells': '0.180', 'Spermatogonia': '0.610', 'Spermatocytes': '0.647', 'Early spermatids': '0.148', 'Late spermatids': '-0.387', 'Oocytes': '43.4', 'Cytotrophoblasts': '19.4', 'Syncytiotrophoblasts': '6.1', 'Extravillous trophoblasts': '16.8', 'Endothelial cells': '12.0', 'Lymphatic endothelial cells': '10.0', 'Cardiomyocytes': '0.460', 'Skeletal myocytes': '0.225', 'Smooth muscle cells': '16.8', 'Adipocytes': '12.9', 'Melanocytes': '0.173', 'Fibroblasts': '8.3', 'Peritubular cells': '0.242', 'Endometrial stromal cells': '10.9', 'Ovarian stromal cells': '9.1', 'Undifferentiated cells': '24.9', 'T-cells': '14.4', 'B-cells': '14.2', 'Plasma cells': '23.0', 'Nk-cells': '10.4', 'Granulocytes': '19.0', 'Monocytes': '8.9', 'Macrophages': '11.4', 'Hofbauer cells': '10.7', 'Kupffer cells': '9.0', 'Dendritic cells': '12.1', 'Langerhans cells': '0.111', 'Erythroid cells': '0.065', 'Adipocytes (Subcutaneous)': '-0.536', 'Adipocytes (Visceral)': '-0.465', 'Breast glandular cells (progenitors)': '0.372', 'Adipocytes (Breast)': '-0.609', 'Colon enterocytes': '-0.126', 'Colon enteroendocrine cells': '0.169', 'Enteric glia cells': '0.180', 'Mitotic cells (Colon)': '0.075', 'Mitotic cells (Heart)': '0.526', 'Podocytes': '-0.142', 'Ascending Loop of Henle cells': '0.411', 'Intercalated cells': '-0.109', 'Cholangiocyte': '0.448', 'NK-cells (Liver)': '-0.211', 'Respiratory ciliated cells': '0.095', 'Mitotic cells (Lung)': '0.086', 'NK-cells (Lung)': '0.325', 'B-cells (Lung)': '0.241', 'Alpha cells': '0.328', 'Beta cells': '0.215', 'Prostate glandular cells': '-0.383', 'Prostate basal glandular cells': '0.019', 'Urothelial cells': '0.049', 'Keratinocyte (other)': '0.501', 'Keratinocyte (granular)': '0.182', 'Hair cortex cells': '-0.318', 'Inner root sheath cells': '-0.275', 'Outer root sheath cells': '-0.277', 'Sebaceous gland cells': '-0.181', 'Eccrine sweat gland cells': '-0.354', 'Adipocytes (Skin)': '-0.447', 'Mitotic cells (Skin)': '0.044', 'Parietal cells': '-0.683', 'Chief cells': '-0.600', 'Gastric mucous cells': '-0.315', 'Gastric enteroendocrine cells': '-0.416', 'Mitotic cells (Stomach)': '0.164', 'Parafollicular cells': '-0.038', 'Thyroid glandular cells': '-0.023', 'Mitotic cells (Thyroid)': '0.127', 'Adrenal cortex cells': '0.269', 'Adrenal medulla cells': '0.132', 'Mitotic cells (Adrenal gland)': '0.500', 'Minor salivary glandular cells': '0.190', 'Minor salivary gland ductal cells': '-0.200', 'Minor salivary gland basal cells': '0.755', 'Mitotic cells (Minor salivary gland)': '0.732', 'Adipocytes (Minor salivary gland)': '0.297', 'Somatotropes': '0.157', 'Lactotropes': '-0.127', 'Gonadotropes': '0.092', 'Corticotropes': '-0.248', 'Thyrotropes': '-0.139', 'Undifferentiated cells (Pituitary gland)': '0.144', 'Mitotic cells (Spleen)': '0.366', 'Platelets': '-0.111', 'Erythrocytes': '0.102', 'Hematopoietic stem cells': '-0.026', 'B-cells (Spleen)': '0.288', 'NK-cells (Spleen)': '0.215', 'Amygdala excitatory': '3.2', 'Cerebellar inhibitory': '6.0', 'Cge interneuron': '10.9', 'Deep-layer corticothalamic and 6b': '33.1', 'Deep-layer intratelencephalic': '5.2', 'Deep-layer near-projecting': '22.0', 'Eccentric medium spiny neuron': '15.9', 'Hippocampal ca1-3': '2.2', 'Hippocampal ca4': '0.1', 'Hippocampal dentate gyrus': '0.5', 'Lamp5-lhx6 and chandelier': '8.0', 'Lower rhombic lip': '6.2', 'Mammillary body': '7.6', 'Medium spiny neuron': '1.5', 'Mge interneuron': '10.6', 'Midbrain-derived inhibitory': '1.6', 'Miscellaneous': '36.0', 'Splatter': '5.8', 'Thalamic excitatory': '12.0', 'Upper rhombic lip': '0.6', 'Upper-layer intratelencephalic': '7.9', 'Astrocyte': '46.0', 'Bergmann glia': '37.5', 'Central nervous system macrophage': '56.8', 'Choroid plexus epithelial cell': '6.6', 'Committed oligodendrocyte precursor': '35.8', 'Ependymal cell': '21.5', 'Oligodendrocyte': '53.3', 'Oligodendrocyte precursor cell': '47.3', 'Endothelial cell': '34.6', 'Pericyte': '40.1', 'Vascular associated smooth muscle cell': '66.3', 'Fibroblast': '28.8', 'Leukocyte': '46.8', 'Basophil': '6.7', 'Eosinophil': '5.8', 'Neutrophil': '0.2', 'Classical monocyte': '3.2', 'Non-classical monocyte': '9.0', 'Intermediate monocyte': '7.7', 'T-reg': '14.4', 'GdT-cell': '4.6', 'MAIT T-cell': '8.6', 'Memory CD4 T-cell': '5.5', 'Naive CD4 T-cell': '5.8', 'Memory CD8 T-cell': '5.5', 'Naive CD8 T-cell': '5.2', 'Memory B-cell': '9.8', 'Naive B-cell': '19.9', 'Plasmacytoid DC': '11.6', 'Myeloid DC': '7.4', 'NK-cell': '8.9', 'Total PBMC': '10.9', 'Vd2 gdTCR': '8.7', 'Memory CD4 T-cell Th1\\/Th17': '6.1', 'Memory CD4 T-cell Th17': '8.0', 'Memory CD4 T-cell Th2': '10.3', 'Non-Vd2 gdTCR': '9.5', 'Memory CD4 T-cell Th1': '5.8', 'Memory CD4 T-cell TFH': '7.0', 'Terminal effector memory CD4 T-cell': '8.2', 'Central memory CD8 T-cell': '11.6', 'Effector memory CD8 T-cell': '12.0', 'Terminal effector memory CD8 T-cell': '10.5', 'Non-switched memory B-cell': '13.5', 'Plasmablast': '23.4', 'Switched memory B-cell': '15.6', 'Exhausted memory B-cell': '15.9', 'Progenitor cell': '10.2', 'Memory T-reg': '18.9', 'Naive CD4 T-cell activated': '2.3', 'Naive CD8 T-cell activated': '2.3', 'Naive T-reg': '9.3'}
1JM7, 2NTE, 2R1Z, 3C5R, 3FA2, 6M14, 7E8I, 7JZV, 7LYB, 7LYC, 8GRQ
{'Adipose Tissue': 2.910929941860465, 'Adrenal Gland': 0.8643201550387597, 'Bladder': 3.9184761904761904, 'Blood': 3.931931442411195, 'Blood Vessel': 6.315702471910112, 'Brain': 1.0467182967448905, 'Breast': 3.646927668845316, 'Cervix Uteri': 5.617421052631578, 'Colon': 4.011631450577664, 'Esophagus': 5.0190460207612455, 'Fallopian Tube': 4.635555555555555, 'Heart': 1.0768155516840885, 'Kidney': 0.818057191011236, 'Liver': 0.5453137168141593, 'Lung': 5.146846020761245, 'Muscle': 2.964216313823163, 'Nerve': 6.576410339256866, 'Ovary': 3.875107777777778, 'Pancreas': 1.0827021341463414, 'Pituitary': 2.3553250883392227, 'Prostate': 3.925248163265306, 'Salivary Gland': 3.0072925925925924, 'Skin': 11.324079601990048, 'Small Intestine': 3.5422133689839574, 'Spleen': 3.2281825726141076, 'Stomach': 2.21493426183844, 'Testis': 6.307437673130194, 'Thyroid': 3.072856355283308, 'Uterus': 6.535781690140845, 'Vagina': 7.591160256410256}
[39.93, 46.46, 52.9, 44.21, 41.4, 39.93, 35.91, 38.61, 36.44, 36.25, 34.86, 32.82, 32.01, 32.75, 31.69, 35.64, 36.35, 34.66, 33.32, 32.71, 35.01, 30.17, 37.05, 36.53, 48.19, 58.22, 64.94, 73.22, 78.33, 82.63, 85.79, 89.39, 87.89, 85.58, 83.93, 89.1, 89.27, 90.66, 87.86, 86.2, 82.97, 72.75, 73.3, 76.44, 82.38, 82.41, 79.49, 86.6, 76.32, 85.48, 88.69, 84.35, 87.75, 90.57, 88.72, 89.46, 87.48, 85.3, 81.72, 79.46, 77.26, 69.01, 67.1, 62.83, 67.71, 74.96, 82.95, 86.74, 86.35, 86.49, 84.6, 85.99, 85.64, 87.19, 89.23, 89.3, 90.62, 84.21, 85.42, 83.34, 84.28, 89.8, 89.78, 87.53, 87.64, 85.98, 81.31, 80.85, 78.74, 80.15, 70.67, 69.91, 72.91, 77.13, 83.26, 84.67, 90.36, 89.7, 92.74, 89.99, 92.55, 88.84, 87.15, 83.78, 78.78, 81.48, 78.75, 84.94, 88.04, 89.37, 92.07, 91.77, 92.31, 91.07, 90.65, 87.61, 83.41, 78.8, 63.24, 54.89, 47.42, 40.03, 40.26, 30.18, 41.24, 38.09, 36.95, 39.02, 37.83, 36.36, 36.19, 34.8, 36.01, 35.89, 38.28, 40.63, 35.0, 43.8, 39.75, 41.2, 46.04, 45.19, 52.52, 50.11, 47.93, 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32.93, 31.34, 34.61, 29.21, 37.22, 33.03, 33.79, 32.16, 35.06, 28.41, 36.29, 34.88, 34.95, 33.23, 30.73, 37.61, 31.07, 34.65, 30.3, 29.79, 32.78, 35.29, 34.36, 34.31, 29.73, 34.2, 32.18, 30.4, 34.16, 29.96, 32.01, 32.54, 29.01, 27.81, 33.18, 29.18, 34.95, 27.64, 36.06, 31.68, 37.68, 36.65, 35.24, 36.99, 35.99, 29.44, 27.82, 31.92, 33.99, 30.72, 34.8, 31.25, 30.84, 31.75, 34.35, 36.97, 36.46, 35.4, 35.54, 34.19, 31.59, 28.45, 31.29, 33.66, 30.54, 32.58, 33.04, 34.63, 33.09, 30.94, 33.61, 27.94, 26.04, 30.61, 31.43, 42.77, 37.96, 32.73, 31.91, 35.72, 32.75, 34.89, 34.05, 33.97, 36.06, 34.07, 32.66, 34.17, 31.25, 33.94, 30.08, 32.73, 28.17, 32.67, 31.07, 27.31, 33.91, 29.35, 29.81, 26.8, 31.95, 30.34, 34.7, 33.73, 29.85, 29.79, 33.71, 30.32, 31.44, 31.99, 29.58, 31.67, 33.93, 41.91, 40.81, 38.93, 36.5, 40.68, 40.29, 32.71, 29.86, 30.43, 34.25, 31.9, 36.81, 33.33, 30.09, 29.84, 30.74, 34.9, 40.39, 48.44, 63.85, 79.98, 87.63, 89.45, 89.79, 87.97, 88.54, 92.27, 93.91, 94.79, 96.37, 96.01, 95.73, 96.36, 96.84, 95.97, 95.92, 95.03, 96.41, 96.51, 96.21, 95.75, 96.29, 95.82, 95.33, 94.91, 94.15, 92.77, 91.25, 87.12, 90.32, 90.16, 93.1, 91.54, 90.47, 90.64, 91.29, 88.94, 87.19, 87.93, 92.97, 94.37, 96.16, 96.92, 96.49, 96.06, 97.1, 96.9, 94.98, 95.42, 95.57, 97.55, 96.76, 96.77, 97.58, 97.25, 96.57, 96.06, 96.01, 94.33, 92.86, 92.49, 89.22, 91.96, 90.12, 92.86, 89.66, 86.48, 86.41, 86.59, 85.93, 84.96, 84.12, 90.14, 92.16, 94.5, 94.95, 94.22, 94.5, 95.35, 94.72, 93.51, 93.92, 93.1, 95.65, 94.01, 94.77, 96.71, 95.26, 94.73, 94.97, 94.65, 93.16, 92.44, 90.09, 87.17, 90.36, 88.18, 89.15, 86.03, 84.76, 84.96, 86.3, 80.19, 83.85, 83.16, 87.87, 90.42, 91.21, 91.92, 90.91, 88.84, 86.61, 85.08, 88.28, 87.07, 87.27, 90.04, 89.63, 88.05, 87.78, 88.15, 84.44, 73.74, 55.96, 54.76, 41.29, 32.46, 32.4, 30.71, 30.47, 37.63, 31.32, 32.01, 27.76, 24.07, 26.34, 34.47, 33.01, 27.35, 30.27, 29.46, 37.54, 49.22, 53.39, 53.56, 68.76, 87.95, 92.42, 95.16, 96.49, 96.63, 95.67, 95.48, 92.54, 94.2, 95.52, 95.25, 95.52, 96.08, 95.28, 96.08, 96.51, 96.23, 96.21, 95.89, 95.71, 95.28, 94.65, 93.52, 92.35, 92.55, 92.76, 94.77, 94.39, 95.0, 92.44, 93.35, 93.82, 91.86, 88.78, 91.98, 95.0, 94.32, 96.63, 96.98, 97.26, 96.9, 95.35, 90.65, 89.32, 88.99, 87.69, 87.58, 90.19, 93.77, 94.66, 95.66, 95.74, 97.0, 96.92, 96.19, 97.08, 96.78, 94.82, 94.58, 95.44, 96.48, 96.78, 96.88, 96.98, 96.5, 95.98, 96.82, 96.45, 96.04, 96.13, 96.03, 95.68, 95.72, 93.85, 91.3, 91.75, 91.07, 92.62, 93.21, 95.04, 93.44, 93.8, 95.93, 95.91, 94.93, 93.14, 92.8, 93.76, 95.71, 94.21, 95.0, 95.97, 94.7, 91.88, 91.83, 89.81, 87.34, 84.4, 82.32, 87.35, 88.62, 93.33, 95.64, 95.92, 90.19, 87.41, 93.58, 94.5, 96.84, 95.89, 95.34, 92.16, 88.03, 87.26, 89.91, 86.82, 85.56, 88.73, 93.03, 93.3, 94.49, 95.39, 95.65, 96.3, 95.78, 97.24, 96.89, 95.28, 95.53, 94.93, 91.93, 94.05, 92.57, 94.39, 92.92, 91.02, 91.05, 91.87, 89.92, 87.38, 78.94, 76.51, 80.35, 68.27, 71.43, 72.93, 71.84, 68.42, 71.65, 74.67, 81.6, 86.6, 90.29, 88.08, 92.62, 92.3, 88.86, 83.65, 85.55, 89.02, 89.63, 92.18, 87.73, 86.15, 89.56, 92.21, 94.15, 96.02, 95.33, 95.93, 93.67, 90.83, 80.92, 73.3, 70.45, 73.16, 81.82, 82.64, 86.73, 85.97, 88.12, 90.73, 91.17, 87.78, 86.21, 87.85, 92.33, 94.88, 94.33, 95.25, 94.68, 94.69, 93.66, 95.68, 96.43, 95.97, 95.96, 97.37, 97.54, 96.24, 96.39, 96.75, 96.48, 95.99, 96.19, 94.45, 91.83, 79.19, 60.93]
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null
Component of an E-cadherin/ catenin adhesion complex composed of at least E-cadherin/CDH1, beta-catenin/CTNNB1 or gamma-catenin/JUP, and potentially alpha-catenin/CTNNA1. Forms a ternary complex composed of ADAM10, CADH1 and EPHA4,
null
null
KLRG1, SPEF1, DLGAP5, AJAP1, RAPGEF2, RAB8B, PIP5K1C, PKP2, TRPV4, CTNNB1, CAV1, DDR1, TBC1D2, CTNNA1, JUP, CTNND1, PSEN1, LIMA1, CDH1, JUP, ADAM10, CADH1 , EPHA4,
null
null
null
null
Homodimer
null
79.91949
0.474025
65.133642
0.582561
847
P12830
Q99741
null
degron_data
CDH1
MGPWSRSLSALLLLLQVSSWLCQEPEPCHPGFDAESYTFTVPRRHLERGRVLGRVNFEDCTGRQRTAYFSLDTRFKVGTDGVITVKRPLRFHNPQIHFLVYAWDSTYRKFSTKVTLNTVGHHHRPPPHQASVSGIQAELLTFPNSSPGLRRQKRDWVIPPISCPENEKGPFPKNLVQIKSNKDKEGKVFYSITGQGADTPPVGVFIIERETGWLKVTEPLDRERIATYTLFSHAVSSNGNAVEDPMEILITVTDQNDNKPEFTQEVFKGSVMEGALPGTSVMEVTATDADDDVNTYNAAIAYTILSQDPELPDKNMFTINRNTGVISVVTTGLDRESFPTYTLVVQAADLQGEGLSTTATAVITVTDTNDNPPIFNPTTYKGQVPENEANVVITTLKVTDADAPNTPAWEAVYTILNDDGGQFVVTTNPVNNDGILKTAKGLDFEAKQQYILHVAVTNVVPFEVSLTTSTATVTVDVLDVNEAPIFVPPEKRVEVSEDFGVGQEITSYTAQEPDTFMEQKITYRIWRDTANWLEINPDTGAISTRAELDREDFEHVKNSTYTALIIATDNGSPVATGTGTLLLILSDVNDNAPIPEPRTIFFCERNPKPQVINIIDADLPPNTSPFTAELTHGASANWTIQYNDPTQESIILKPKMALEVGDYKINLKLMDNQNKDQVTTLEVSVCDCEGAAGVCRKAQPVEAGLQIPAILGILGGILALLILILLLLLFLRRRAVVKEPLLPPEDDTRDNVYYYDEEGGGEEDQDFDLSQLHRGLDARPEVTRNDVAPTLMSVPRYLPRPANPDEIGNFIDENLKAADTDPTAPPYDSLLVFDYEGSGSEAASLSSLNSSESDKDQDYDYLNEWGNRFKKLADMYGGGEDD
Homo sapiens
Cell junction, adherens junction, Cell membrane, Endosome, Golgi apparatus, trans-Golgi network, Cytoplasm, Cell junction, desmosome
Tissue enhanced (parathyroid)
{'Ciliated cells': '119.1', 'Basal respiratory cells': '71.1', 'Club cells': '97.3', 'Ionocytes': '81.0', 'Mucus glandular cells': '155.0', 'Serous glandular cells': '67.8', 'Gastric mucus-secreting cells': '133.2', 'Proximal enterocytes': '140.9', 'Paneth cells': '125.1', 'Distal enterocytes': '307.5', 'Intestinal goblet cells': '173.5', 'Exocrine glandular cells': '-0.605', 'Basal prostatic cells': '68.3', 'Prostatic glandular cells': '186.7', 'Breast glandular cells': '0.773', 'Breast myoepithelial cells': '0.700', 'Glandular and luminal cells': '313.0', 'Secretory cells': '82.3', 'Basal keratinocytes': '102.5', 'Suprabasal keratinocytes': '162.6', 'Basal squamous epithelial cells': '51.0', 'Squamous epithelial cells': '106.9', 'Alveolar cells type 1': '0.437', 'Alveolar cells type 2': '0.706', 'Salivary duct cells': '95.9', 'Ductal cells': '0.541', 'Hepatocytes': '0.600', 'Cholangiocytes': '129.7', 'Proximal tubular cells': '0.042', 'Distal tubular cells': '0.0', 'Collecting duct cells': '143.9', 'Mesothelial cells': '0.799', 'Sertoli cells': '0.252', 'Granulosa cells': '12.9', 'Enteroendocrine cells': '92.4', 'Pancreatic endocrine cells': '78.1', 'Leydig cells': '0.264', 'Excitatory neurons': '0.7', 'Inhibitory neurons': '1.3', 'Cone photoreceptor cells': '0.0', 'Rod photoreceptor cells': '0.0', 'Bipolar cells': '0.2', 'Horizontal cells': '0.6', 'Astrocytes': '0.6', 'Oligodendrocyte precursor cells': '0.5', 'Oligodendrocytes': '29.9', 'Microglial cells': '0.9', 'Muller glia cells': '0.1', 'Schwann cells': '0.131', 'Spermatogonia': '0.392', 'Spermatocytes': '0.193', 'Early spermatids': '-0.217', 'Late spermatids': '-0.290', 'Oocytes': '16.9', 'Cytotrophoblasts': '119.2', 'Syncytiotrophoblasts': '45.0', 'Extravillous trophoblasts': '24.9', 'Endothelial cells': '6.1', 'Lymphatic endothelial cells': '0.4', 'Cardiomyocytes': '0.135', 'Skeletal myocytes': '0.107', 'Smooth muscle cells': '5.8', 'Adipocytes': '2.1', 'Melanocytes': '0.335', 'Fibroblasts': '6.5', 'Peritubular cells': '0.210', 'Endometrial stromal cells': '27.7', 'Ovarian stromal cells': '0.7', 'Undifferentiated cells': '101.6', 'T-cells': '2.9', 'B-cells': '4.4', 'Plasma cells': '6.1', 'Nk-cells': '0.0', 'Granulocytes': '8.4', 'Monocytes': '0.0', 'Macrophages': '6.0', 'Hofbauer cells': '4.3', 'Kupffer cells': '1.0', 'Dendritic cells': '5.9', 'Langerhans cells': '0.304', 'Erythroid cells': '0.036', 'Adipocytes (Subcutaneous)': '-0.081', 'Adipocytes (Visceral)': '-0.209', 'Breast glandular cells (progenitors)': '0.538', 'Adipocytes (Breast)': '-0.689', 'Colon enterocytes': '0.790', 'Colon enteroendocrine cells': '0.112', 'Enteric glia cells': '-0.048', 'Mitotic cells (Colon)': '0.299', 'Mitotic cells (Heart)': '0.120', 'Podocytes': '-0.118', 'Ascending Loop of Henle cells': '0.475', 'Intercalated cells': '0.212', 'Cholangiocyte': '0.090', 'NK-cells (Liver)': '-0.005', 'Respiratory ciliated cells': '-0.012', 'Mitotic cells (Lung)': '0.071', 'NK-cells (Lung)': '-0.266', 'B-cells (Lung)': '-0.296', 'Alpha cells': '0.270', 'Beta cells': '0.152', 'Prostate glandular cells': '0.764', 'Prostate basal glandular cells': '0.540', 'Urothelial cells': '0.205', 'Keratinocyte (other)': '0.510', 'Keratinocyte (granular)': '0.055', 'Hair cortex cells': '0.080', 'Inner root sheath cells': '0.131', 'Outer root sheath cells': '0.175', 'Sebaceous gland cells': '0.156', 'Eccrine sweat gland cells': '-0.207', 'Adipocytes (Skin)': '-0.244', 'Mitotic cells (Skin)': '0.442', 'Parietal cells': '0.654', 'Chief cells': '0.649', 'Gastric mucous cells': '0.781', 'Gastric enteroendocrine cells': '0.590', 'Mitotic cells (Stomach)': '0.445', 'Parafollicular cells': '0.173', 'Thyroid glandular cells': '0.865', 'Mitotic cells (Thyroid)': '-0.081', 'Adrenal cortex cells': '0.051', 'Adrenal medulla cells': '0.087', 'Mitotic cells (Adrenal gland)': '0.072', 'Minor salivary glandular cells': '0.371', 'Minor salivary gland ductal cells': '-0.142', 'Minor salivary gland basal cells': '0.582', 'Mitotic cells (Minor salivary gland)': '0.567', 'Adipocytes (Minor salivary gland)': '0.050', 'Somatotropes': '0.121', 'Lactotropes': '0.322', 'Gonadotropes': '0.330', 'Corticotropes': '0.180', 'Thyrotropes': '0.496', 'Undifferentiated cells (Pituitary gland)': '-0.108', 'Mitotic cells (Spleen)': '-0.228', 'Platelets': '-0.050', 'Erythrocytes': '-0.158', 'Hematopoietic stem cells': '-0.211', 'B-cells (Spleen)': '0.266', 'NK-cells (Spleen)': '0.309', 'Amygdala excitatory': '1.0', 'Cerebellar inhibitory': '0.9', 'Cge interneuron': '0.7', 'Deep-layer corticothalamic and 6b': '1.5', 'Deep-layer intratelencephalic': '0.7', 'Deep-layer near-projecting': '0.7', 'Eccentric medium spiny neuron': '0.6', 'Hippocampal ca1-3': '1.9', 'Hippocampal ca4': '1.2', 'Hippocampal dentate gyrus': '1.1', 'Lamp5-lhx6 and chandelier': '0.5', 'Lower rhombic lip': '0.8', 'Mammillary body': '0.6', 'Medium spiny neuron': '0.7', 'Mge interneuron': '1.7', 'Midbrain-derived inhibitory': '0.7', 'Miscellaneous': '0.9', 'Splatter': '3.8', 'Thalamic excitatory': '0.5', 'Upper rhombic lip': '0.8', 'Upper-layer intratelencephalic': '0.6', 'Astrocyte': '4.4', 'Bergmann glia': '0.2', 'Central nervous system macrophage': '0.6', 'Choroid plexus epithelial cell': '52.1', 'Committed oligodendrocyte precursor': '41.5', 'Ependymal cell': '4.8', 'Oligodendrocyte': '53.1', 'Oligodendrocyte precursor cell': '2.4', 'Endothelial cell': '0.7', 'Pericyte': '0.3', 'Vascular associated smooth muscle cell': '0.0', 'Fibroblast': '17.4', 'Leukocyte': '1.1', 'Basophil': '0.0', 'Eosinophil': '0.0', 'Neutrophil': '0.0', 'Classical monocyte': '0.0', 'Non-classical monocyte': '0.0', 'Intermediate monocyte': '0.0', 'T-reg': '2.3', 'GdT-cell': '0.0', 'MAIT T-cell': '0.0', 'Memory CD4 T-cell': '0.0', 'Naive CD4 T-cell': '0.1', 'Memory CD8 T-cell': '0.2', 'Naive CD8 T-cell': '0.3', 'Memory B-cell': '0.0', 'Naive B-cell': '0.1', 'Plasmacytoid DC': '46.6', 'Myeloid DC': '8.5', 'NK-cell': '0.1', 'Total PBMC': '0.7', 'Vd2 gdTCR': '0.0', 'Memory CD4 T-cell Th1\\/Th17': '0.1', 'Memory CD4 T-cell Th17': '0.2', 'Memory CD4 T-cell Th2': '2.9', 'Non-Vd2 gdTCR': '0.1', 'Memory CD4 T-cell Th1': '0.3', 'Memory CD4 T-cell TFH': '0.5', 'Terminal effector memory CD4 T-cell': '0.0', 'Central memory CD8 T-cell': '4.8', 'Effector memory CD8 T-cell': '0.0', 'Terminal effector memory CD8 T-cell': '0.6', 'Non-switched memory B-cell': '0.0', 'Plasmablast': '3.3', 'Switched memory B-cell': '0.0', 'Exhausted memory B-cell': '0.7', 'Progenitor cell': '2.3', 'Memory T-reg': '1.3', 'Naive CD4 T-cell activated': '0.3', 'Naive CD8 T-cell activated': '0.6', 'Naive T-reg': '0.1'}
1O6S, 2O72, 2OMT, 2OMU, 2OMV, 2OMX, 2OMY, 2OMZ, 3FF7, 3FF8, 3L6X, 3L6Y, 4ZT1, 4ZTE, 6CXY, 6OLE, 6OLF, 6OLG, 6VEL, 7STZ, 8H62
{'Adipose Tissue': 1.2125261088039867, 'Adrenal Gland': 0.1914223992248062, 'Bladder': 39.2033519047619, 'Blood': 1.340954264800861, 'Blood Vessel': 0.3121561692883895, 'Brain': 0.8550442199091597, 'Breast': 38.54918344226579, 'Cervix Uteri': 23.539115789473684, 'Colon': 43.41292142490372, 'Esophagus': 53.97513367404844, 'Fallopian Tube': 14.900277777777776, 'Heart': 0.119140469221835, 'Kidney': 25.040449438202245, 'Liver': 26.60802654867257, 'Lung': 35.447986366782004, 'Muscle': 0.1378936151930261, 'Nerve': 17.518468982229404, 'Ovary': 3.6515122222222223, 'Pancreas': 56.89676829268293, 'Pituitary': 24.68741660777385, 'Prostate': 61.279967346938776, 'Salivary Gland': 92.01685185185184, 'Skin': 79.77571720232172, 'Small Intestine': 71.7519320855615, 'Spleen': 10.061029045643156, 'Stomach': 58.07813805013927, 'Testis': 0.8144204986149585, 'Thyroid': 135.176797856049, 'Uterus': 1.442593943661972, 'Vagina': 86.52345512820513}
CDC6
MPQTRSQAQATISFPKRKLSRALNKAKNSSDAKLEPTNVQTVTCSPRVKALPLSPRKRLGDDNLCNTPHLPPCSPPKQGKKENGPPHSHTLKGRRLVFDNQLTIKSPSKRELAKVHQNKILSSVRKSQEITTNSEQRCPLKKESACVRLFKQEGTCYQQAKLVLNTAVPDRLPAREREMDVIRNFLREHICGKKAGSLYLSGAPGTGKTACLSRILQDLKKELKGFKTIMLNCMSLRTAQAVFPAIAQEICQEEVSRPAGKDMMRKLEKHMTAEKGPMIVLVLDEMDQLDSKGQDVLYTLFEWPWLSNSHLVLIGIANTLDLTDRILPRLQAREKCKPQLLNFPPYTRNQIVTILQDRLNQVSRDQVLDNAAVQFCARKVSAVSGDVRKALDVCRRAIEIVESDVKSQTILKPLSECKSPSEPLIPKRVGLIHISQVISEVDGNRMTLSQEGAQDSFPLQQKILVCSLMLLIRQLKIKEVTLGKLYEAYSKVCRKQQVAAVDQSECLSLSGLLEARGILGLKRNKETRLTKVFFKIEEKEIEHALKDKALIGNILATGLP
Homo sapiens
Nucleus, Cytoplasm
Tissue enhanced (bone marrow, lymphoid tissue)
{'Ciliated cells': '0.4', 'Basal respiratory cells': '3.6', 'Club cells': '1.6', 'Ionocytes': '0.7', 'Mucus glandular cells': '1.3', 'Serous glandular cells': '0.7', 'Gastric mucus-secreting cells': '3.5', 'Proximal enterocytes': '0.5', 'Paneth cells': '1.8', 'Distal enterocytes': '3.6', 'Intestinal goblet cells': '6.2', 'Exocrine glandular cells': '-0.490', 'Basal prostatic cells': '0.7', 'Prostatic glandular cells': '0.0', 'Breast glandular cells': '0.231', 'Breast myoepithelial cells': '0.343', 'Glandular and luminal cells': '4.9', 'Secretory cells': '0.8', 'Basal keratinocytes': '5.8', 'Suprabasal keratinocytes': '2.4', 'Basal squamous epithelial cells': '4.4', 'Squamous epithelial cells': '8.6', 'Alveolar cells type 1': '-0.330', 'Alveolar cells type 2': '0.024', 'Salivary duct cells': '1.4', 'Ductal cells': '0.373', 'Hepatocytes': '0.272', 'Cholangiocytes': '0.0', 'Proximal tubular cells': '0.148', 'Distal tubular cells': '0.0', 'Collecting duct cells': '0.0', 'Mesothelial cells': '0.071', 'Sertoli cells': '0.170', 'Granulosa cells': '1.1', 'Enteroendocrine cells': '1.6', 'Pancreatic endocrine cells': '8.5', 'Leydig cells': '0.193', 'Excitatory neurons': '1.9', 'Inhibitory neurons': '0.6', 'Cone photoreceptor cells': '0.0', 'Rod photoreceptor cells': '0.3', 'Bipolar cells': '0.2', 'Horizontal cells': '0.6', 'Astrocytes': '0.6', 'Oligodendrocyte precursor cells': '0.0', 'Oligodendrocytes': '0.2', 'Microglial cells': '0.0', 'Muller glia cells': '0.5', 'Schwann cells': '-0.019', 'Spermatogonia': '0.432', 'Spermatocytes': '0.787', 'Early spermatids': '-0.067', 'Late spermatids': '-0.213', 'Oocytes': '53.7', 'Cytotrophoblasts': '25.2', 'Syncytiotrophoblasts': '18.4', 'Extravillous trophoblasts': '35.1', 'Endothelial cells': '1.6', 'Lymphatic endothelial cells': '1.1', 'Cardiomyocytes': '0.160', 'Skeletal myocytes': '-0.069', 'Smooth muscle cells': '1.8', 'Adipocytes': '1.9', 'Melanocytes': '0.441', 'Fibroblasts': '4.6', 'Peritubular cells': '0.039', 'Endometrial stromal cells': '2.4', 'Ovarian stromal cells': '1.2', 'Undifferentiated cells': '22.6', 'T-cells': '2.2', 'B-cells': '3.5', 'Plasma cells': '32.6', 'Nk-cells': '2.2', 'Granulocytes': '0.1', 'Monocytes': '0.2', 'Macrophages': '1.5', 'Hofbauer cells': '6.1', 'Kupffer cells': '1.1', 'Dendritic cells': '0.4', 'Langerhans cells': '0.193', 'Erythroid cells': '-0.127', 'Adipocytes (Subcutaneous)': '-0.364', 'Adipocytes (Visceral)': '-0.236', 'Breast glandular cells (progenitors)': '0.314', 'Adipocytes (Breast)': '-0.351', 'Colon enterocytes': '0.268', 'Colon enteroendocrine cells': '-0.009', 'Enteric glia cells': '-0.034', 'Mitotic cells (Colon)': '0.555', 'Mitotic cells (Heart)': '0.582', 'Podocytes': '-0.139', 'Ascending Loop of Henle cells': '0.218', 'Intercalated cells': '-0.153', 'Cholangiocyte': '0.258', 'NK-cells (Liver)': '-0.293', 'Respiratory ciliated cells': '-0.064', 'Mitotic cells (Lung)': '0.542', 'NK-cells (Lung)': '-0.154', 'B-cells (Lung)': '-0.043', 'Alpha cells': '0.191', 'Beta cells': '0.090', 'Prostate glandular cells': '0.072', 'Prostate basal glandular cells': '0.221', 'Urothelial cells': '0.248', 'Keratinocyte (other)': '0.219', 'Keratinocyte (granular)': '-0.260', 'Hair cortex cells': '0.240', 'Inner root sheath cells': '0.359', 'Outer root sheath cells': '0.406', 'Sebaceous gland cells': '0.171', 'Eccrine sweat gland cells': '0.051', 'Adipocytes (Skin)': '-0.140', 'Mitotic cells (Skin)': '0.766', 'Parietal cells': '-0.085', 'Chief cells': '0.049', 'Gastric mucous cells': '0.375', 'Gastric enteroendocrine cells': '0.150', 'Mitotic cells (Stomach)': '0.765', 'Parafollicular cells': '-0.057', 'Thyroid glandular cells': '-0.138', 'Mitotic cells (Thyroid)': '0.373', 'Adrenal cortex cells': '0.398', 'Adrenal medulla cells': '-0.021', 'Mitotic cells (Adrenal gland)': '0.431', 'Minor salivary glandular cells': '0.116', 'Minor salivary gland ductal cells': '-0.222', 'Minor salivary gland basal cells': '0.615', 'Mitotic cells (Minor salivary gland)': '0.784', 'Adipocytes (Minor salivary gland)': '0.160', 'Somatotropes': '-0.152', 'Lactotropes': '-0.176', 'Gonadotropes': '0.171', 'Corticotropes': '-0.194', 'Thyrotropes': '-0.146', 'Undifferentiated cells (Pituitary gland)': '0.330', 'Mitotic cells (Spleen)': '0.827', 'Platelets': '0.156', 'Erythrocytes': '0.285', 'Hematopoietic stem cells': '0.230', 'B-cells (Spleen)': '-0.206', 'NK-cells (Spleen)': '-0.219', 'Amygdala excitatory': '2.8', 'Cerebellar inhibitory': '0.6', 'Cge interneuron': '1.0', 'Deep-layer corticothalamic and 6b': '1.6', 'Deep-layer intratelencephalic': '2.9', 'Deep-layer near-projecting': '1.5', 'Eccentric medium spiny neuron': '1.2', 'Hippocampal ca1-3': '1.9', 'Hippocampal ca4': '1.5', 'Hippocampal dentate gyrus': '1.9', 'Lamp5-lhx6 and chandelier': '1.2', 'Lower rhombic lip': '1.1', 'Mammillary body': '1.2', 'Medium spiny neuron': '1.4', 'Mge interneuron': '1.1', 'Midbrain-derived inhibitory': '0.7', 'Miscellaneous': '2.4', 'Splatter': '1.3', 'Thalamic excitatory': '1.8', 'Upper rhombic lip': '1.4', 'Upper-layer intratelencephalic': '5.4', 'Astrocyte': '1.9', 'Bergmann glia': '1.0', 'Central nervous system macrophage': '0.5', 'Choroid plexus epithelial cell': '0.1', 'Committed oligodendrocyte precursor': '0.4', 'Ependymal cell': '1.1', 'Oligodendrocyte': '0.3', 'Oligodendrocyte precursor cell': '0.5', 'Endothelial cell': '0.4', 'Pericyte': '0.4', 'Vascular associated smooth muscle cell': '0.0', 'Fibroblast': '0.2', 'Leukocyte': '0.6', 'Basophil': '0.6', 'Eosinophil': '0.0', 'Neutrophil': '0.4', 'Classical monocyte': '0.2', 'Non-classical monocyte': '0.3', 'Intermediate monocyte': '1.5', 'T-reg': '4.1', 'GdT-cell': '0.8', 'MAIT T-cell': '3.0', 'Memory CD4 T-cell': '0.6', 'Naive CD4 T-cell': '0.4', 'Memory CD8 T-cell': '1.1', 'Naive CD8 T-cell': '0.4', 'Memory B-cell': '0.4', 'Naive B-cell': '0.5', 'Plasmacytoid DC': '7.4', 'Myeloid DC': '0.9', 'NK-cell': '1.9', 'Total PBMC': '5.3', 'Vd2 gdTCR': '0.2', 'Memory CD4 T-cell TFH': '0.4', 'Memory CD4 T-cell Th2': '0.8', 'Memory CD4 T-cell Th17': '0.7', 'Memory CD4 T-cell Th1\\/Th17': '0.7', 'Non-Vd2 gdTCR': '3.2', 'Memory CD4 T-cell Th1': '1.3', 'Terminal effector memory CD4 T-cell': '1.2', 'Central memory CD8 T-cell': '1.7', 'Effector memory CD8 T-cell': '8.7', 'Terminal effector memory CD8 T-cell': '1.5', 'Switched memory B-cell': '3.3', 'Plasmablast': '94.4', 'Non-switched memory B-cell': '0.6', 'Exhausted memory B-cell': '4.9', 'Progenitor cell': '4.1', 'Naive CD4 T-cell activated': '1.0', 'Naive CD8 T-cell activated': '1.2', 'Memory T-reg': '2.1', 'Naive T-reg': '0.5'}
2CCH, 2CCI, 4I5L, 4I5N, 8HT7
{'Adipose Tissue': 1.0135120598006646, 'Adrenal Gland': 1.476743023255814, 'Bladder': 1.1341238095238095, 'Blood': 5.327745414424112, 'Blood Vessel': 0.5764714232209738, 'Brain': 0.7258613058289175, 'Breast': 0.8094962745098039, 'Cervix Uteri': 1.461278947368421, 'Colon': 1.3525910141206676, 'Esophagus': 2.140787570934256, 'Fallopian Tube': 0.9588, 'Heart': 0.4529019512195122, 'Kidney': 0.4478088764044944, 'Liver': 1.4233409292035395, 'Lung': 2.030225605536332, 'Muscle': 0.2054580946450809, 'Nerve': 0.7501828756058159, 'Ovary': 0.9998522222222224, 'Pancreas': 0.8700864024390245, 'Pituitary': 0.6330436042402827, 'Prostate': 0.9005502857142856, 'Salivary Gland': 1.3956925925925927, 'Skin': 5.488745605306799, 'Small Intestine': 2.64122192513369, 'Spleen': 5.095452697095436, 'Stomach': 1.377367409470752, 'Testis': 10.918598337950138, 'Thyroid': 0.8930437212863707, 'Uterus': 0.754343661971831, 'Vagina': 2.244133333333333}
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[51.48, 49.93, 39.8, 53.62, 48.71, 42.59, 49.32, 48.5, 46.5, 48.5, 51.05, 51.09, 46.03, 44.52, 53.46, 43.75, 41.34, 42.13, 39.97, 37.45, 33.81, 38.15, 36.7, 36.01, 36.36, 36.05, 38.36, 34.05, 37.35, 36.94, 37.69, 37.13, 34.88, 39.01, 35.39, 37.79, 34.92, 35.91, 34.91, 36.69, 31.16, 35.2, 30.0, 31.44, 36.7, 32.87, 32.32, 35.84, 36.03, 35.05, 40.96, 47.34, 43.56, 45.34, 40.54, 40.58, 38.38, 37.37, 36.63, 36.75, 37.46, 35.6, 39.07, 35.63, 34.83, 34.47, 41.41, 37.18, 33.08, 40.84, 44.09, 35.77, 36.33, 47.22, 41.04, 39.93, 39.13, 37.86, 31.84, 36.73, 31.61, 35.63, 34.48, 38.42, 46.29, 33.13, 31.23, 37.9, 31.55, 35.46, 33.7, 31.18, 32.77, 32.69, 31.61, 34.3, 34.17, 33.58, 32.46, 36.51, 32.98, 34.3, 28.98, 38.85, 35.42, 35.23, 35.67, 29.1, 36.68, 29.47, 32.6, 33.61, 32.01, 29.3, 32.22, 32.61, 34.46, 33.45, 32.73, 33.16, 33.92, 33.84, 36.92, 34.83, 35.0, 32.52, 35.51, 35.72, 34.72, 33.34, 33.38, 34.58, 31.78, 37.44, 33.51, 36.57, 31.32, 29.06, 33.18, 35.61, 36.0, 34.86, 37.64, 35.71, 34.73, 34.86, 37.8, 39.65, 48.62, 44.36, 46.9, 51.5, 52.72, 60.45, 71.03, 78.11, 81.17, 81.68, 82.36, 81.33, 83.73, 83.44, 81.94, 79.02, 79.92, 77.19, 74.62, 72.64, 72.01, 70.5, 78.47, 83.08, 81.92, 86.37, 90.49, 90.96, 92.66, 92.93, 92.34, 93.58, 94.69, 94.31, 93.58, 94.21, 93.69, 92.84, 92.51, 92.11, 90.37, 89.73, 88.03, 86.33, 84.89, 86.91, 89.23, 90.03, 90.66, 92.13, 91.96, 93.81, 92.22, 91.69, 91.89, 92.09, 89.83, 91.32, 90.49, 92.46, 91.79, 91.24, 92.21, 92.53, 91.45, 90.1, 91.94, 91.29, 89.79, 89.47, 89.22, 88.81, 88.65, 88.22, 84.72, 79.63, 80.42, 87.92, 89.29, 91.1, 92.48, 93.01, 93.4, 93.87, 91.68, 90.68, 91.43, 89.14, 87.58, 88.52, 86.88, 86.59, 87.26, 89.72, 89.06, 87.26, 87.97, 88.51, 85.61, 86.18, 84.63, 81.75, 71.71, 66.66, 58.13, 50.42, 52.59, 51.07, 54.15, 55.41, 60.45, 62.02, 67.93, 70.76, 72.61, 74.25, 76.15, 77.07, 79.85, 80.44, 78.32, 77.42, 77.91, 77.81, 75.62, 66.68, 68.79, 73.84, 83.6, 88.63, 90.87, 93.43, 94.28, 95.31, 94.22, 94.33, 91.81, 90.91, 88.81, 89.12, 87.39, 84.65, 80.67, 76.47, 73.82, 81.3, 84.12, 87.2, 87.25, 84.86, 86.56, 88.41, 86.86, 85.73, 86.15, 85.95, 83.47, 83.87, 78.21, 80.45, 83.56, 86.38, 91.1, 93.23, 93.35, 94.62, 93.87, 94.82, 92.81, 90.75, 82.17, 76.57, 74.58, 71.79, 70.53, 73.95, 74.0, 70.3, 65.95, 71.29, 69.94, 67.95, 64.46, 66.6, 68.53, 66.63, 68.29, 68.76, 77.49, 83.87, 88.04, 89.31, 92.3, 92.2, 93.25, 92.61, 93.64, 94.98, 94.83, 95.13, 95.21, 94.91, 94.24, 94.22, 93.04, 91.98, 90.68, 89.52, 88.47, 86.33, 84.43, 84.06, 80.63, 70.24, 62.71, 59.6, 61.03, 68.52, 77.17, 81.81, 87.36, 89.72, 91.53, 91.82, 92.43, 94.16, 93.64, 93.44, 95.08, 94.6, 93.26, 93.59, 94.27, 93.3, 90.41, 87.27, 90.23, 92.47, 92.05, 92.44, 91.93, 92.67, 92.32, 91.83, 91.81, 90.72, 90.58, 90.69, 90.78, 89.32, 88.99, 88.11, 87.54, 87.02, 86.3, 85.44, 82.81, 81.8, 79.88, 75.37, 68.37, 64.55, 58.87, 49.08, 40.82, 44.58, 39.28, 34.17, 28.08, 30.69, 30.32, 33.01, 31.06, 29.02, 35.07, 43.97, 45.73, 56.77, 67.05, 74.92, 79.02, 84.65, 88.11, 88.93, 88.35, 89.67, 89.35, 88.86, 89.88, 88.35, 85.91, 84.59, 82.14, 75.8, 64.82, 61.09, 59.7, 56.22, 53.85, 47.34, 47.09, 44.35, 44.36, 39.0, 38.47, 46.5, 52.99, 64.98, 73.67, 86.53, 86.58, 89.32, 89.64, 87.58, 89.12, 90.52, 89.72, 88.37, 89.53, 90.43, 88.06, 87.69, 89.3, 88.08, 85.88, 85.84, 85.52, 85.05, 87.92, 86.55, 90.56, 91.76, 93.04, 92.84, 91.33, 91.05, 92.49, 93.21, 91.34, 90.29, 92.42, 91.22, 89.35, 89.14, 89.75, 88.12, 85.75, 83.53, 83.35, 85.68, 87.85, 86.22, 89.3, 90.17, 89.0, 88.75, 91.52, 90.92, 91.44, 92.08, 91.84, 91.47, 91.98, 90.82, 89.14, 91.29, 88.25, 84.23, 84.77, 85.94, 89.9, 91.65, 91.77, 92.31, 89.72, 89.85, 88.72, 89.38, 87.36, 89.27, 90.28, 92.02, 92.36, 92.79, 91.97, 91.05, 88.26, 84.54, 84.63, 81.26, 80.69, 80.61, 79.57, 79.48, 77.39, 74.79, 75.43, 69.52, 72.87, 73.28, 77.6, 77.23, 76.46, 76.17, 81.54, 79.38, 76.14, 74.28, 67.37, 63.17, 61.79, 49.44]
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null
Component of an E-cadherin/ catenin adhesion complex composed of at least E-cadherin/CDH1, beta-catenin/CTNNB1 or gamma-catenin/JUP, and potentially alpha-catenin/CTNNA1. Forms a ternary complex composed of ADAM10, CADH1 and EPHA4,
null
null
KLRG1, SPEF1, DLGAP5, AJAP1, RAPGEF2, RAB8B, PIP5K1C, PKP2, TRPV4, CTNNB1, CAV1, DDR1, TBC1D2, CTNNA1, JUP, CTNND1, PSEN1, LIMA1, CDH1, JUP, ADAM10, CADH1 , EPHA4,
null
null
null
null
Homodimer
null
79.91949
0.474025
69.693054
0.520054
1,384
P12830
Q9BSJ6-2
null
degron_data
CDH1
MGPWSRSLSALLLLLQVSSWLCQEPEPCHPGFDAESYTFTVPRRHLERGRVLGRVNFEDCTGRQRTAYFSLDTRFKVGTDGVITVKRPLRFHNPQIHFLVYAWDSTYRKFSTKVTLNTVGHHHRPPPHQASVSGIQAELLTFPNSSPGLRRQKRDWVIPPISCPENEKGPFPKNLVQIKSNKDKEGKVFYSITGQGADTPPVGVFIIERETGWLKVTEPLDRERIATYTLFSHAVSSNGNAVEDPMEILITVTDQNDNKPEFTQEVFKGSVMEGALPGTSVMEVTATDADDDVNTYNAAIAYTILSQDPELPDKNMFTINRNTGVISVVTTGLDRESFPTYTLVVQAADLQGEGLSTTATAVITVTDTNDNPPIFNPTTYKGQVPENEANVVITTLKVTDADAPNTPAWEAVYTILNDDGGQFVVTTNPVNNDGILKTAKGLDFEAKQQYILHVAVTNVVPFEVSLTTSTATVTVDVLDVNEAPIFVPPEKRVEVSEDFGVGQEITSYTAQEPDTFMEQKITYRIWRDTANWLEINPDTGAISTRAELDREDFEHVKNSTYTALIIATDNGSPVATGTGTLLLILSDVNDNAPIPEPRTIFFCERNPKPQVINIIDADLPPNTSPFTAELTHGASANWTIQYNDPTQESIILKPKMALEVGDYKINLKLMDNQNKDQVTTLEVSVCDCEGAAGVCRKAQPVEAGLQIPAILGILGGILALLILILLLLLFLRRRAVVKEPLLPPEDDTRDNVYYYDEEGGGEEDQDFDLSQLHRGLDARPEVTRNDVAPTLMSVPRYLPRPANPDEIGNFIDENLKAADTDPTAPPYDSLLVFDYEGSGSEAASLSSLNSSESDKDQDYDYLNEWGNRFKKLADMYGGGEDD
Homo sapiens
Cell junction, adherens junction, Cell membrane, Endosome, Golgi apparatus, trans-Golgi network, Cytoplasm, Cell junction, desmosome
Tissue enhanced (parathyroid)
{'Ciliated cells': '119.1', 'Basal respiratory cells': '71.1', 'Club cells': '97.3', 'Ionocytes': '81.0', 'Mucus glandular cells': '155.0', 'Serous glandular cells': '67.8', 'Gastric mucus-secreting cells': '133.2', 'Proximal enterocytes': '140.9', 'Paneth cells': '125.1', 'Distal enterocytes': '307.5', 'Intestinal goblet cells': '173.5', 'Exocrine glandular cells': '-0.605', 'Basal prostatic cells': '68.3', 'Prostatic glandular cells': '186.7', 'Breast glandular cells': '0.773', 'Breast myoepithelial cells': '0.700', 'Glandular and luminal cells': '313.0', 'Secretory cells': '82.3', 'Basal keratinocytes': '102.5', 'Suprabasal keratinocytes': '162.6', 'Basal squamous epithelial cells': '51.0', 'Squamous epithelial cells': '106.9', 'Alveolar cells type 1': '0.437', 'Alveolar cells type 2': '0.706', 'Salivary duct cells': '95.9', 'Ductal cells': '0.541', 'Hepatocytes': '0.600', 'Cholangiocytes': '129.7', 'Proximal tubular cells': '0.042', 'Distal tubular cells': '0.0', 'Collecting duct cells': '143.9', 'Mesothelial cells': '0.799', 'Sertoli cells': '0.252', 'Granulosa cells': '12.9', 'Enteroendocrine cells': '92.4', 'Pancreatic endocrine cells': '78.1', 'Leydig cells': '0.264', 'Excitatory neurons': '0.7', 'Inhibitory neurons': '1.3', 'Cone photoreceptor cells': '0.0', 'Rod photoreceptor cells': '0.0', 'Bipolar cells': '0.2', 'Horizontal cells': '0.6', 'Astrocytes': '0.6', 'Oligodendrocyte precursor cells': '0.5', 'Oligodendrocytes': '29.9', 'Microglial cells': '0.9', 'Muller glia cells': '0.1', 'Schwann cells': '0.131', 'Spermatogonia': '0.392', 'Spermatocytes': '0.193', 'Early spermatids': '-0.217', 'Late spermatids': '-0.290', 'Oocytes': '16.9', 'Cytotrophoblasts': '119.2', 'Syncytiotrophoblasts': '45.0', 'Extravillous trophoblasts': '24.9', 'Endothelial cells': '6.1', 'Lymphatic endothelial cells': '0.4', 'Cardiomyocytes': '0.135', 'Skeletal myocytes': '0.107', 'Smooth muscle cells': '5.8', 'Adipocytes': '2.1', 'Melanocytes': '0.335', 'Fibroblasts': '6.5', 'Peritubular cells': '0.210', 'Endometrial stromal cells': '27.7', 'Ovarian stromal cells': '0.7', 'Undifferentiated cells': '101.6', 'T-cells': '2.9', 'B-cells': '4.4', 'Plasma cells': '6.1', 'Nk-cells': '0.0', 'Granulocytes': '8.4', 'Monocytes': '0.0', 'Macrophages': '6.0', 'Hofbauer cells': '4.3', 'Kupffer cells': '1.0', 'Dendritic cells': '5.9', 'Langerhans cells': '0.304', 'Erythroid cells': '0.036', 'Adipocytes (Subcutaneous)': '-0.081', 'Adipocytes (Visceral)': '-0.209', 'Breast glandular cells (progenitors)': '0.538', 'Adipocytes (Breast)': '-0.689', 'Colon enterocytes': '0.790', 'Colon enteroendocrine cells': '0.112', 'Enteric glia cells': '-0.048', 'Mitotic cells (Colon)': '0.299', 'Mitotic cells (Heart)': '0.120', 'Podocytes': '-0.118', 'Ascending Loop of Henle cells': '0.475', 'Intercalated cells': '0.212', 'Cholangiocyte': '0.090', 'NK-cells (Liver)': '-0.005', 'Respiratory ciliated cells': '-0.012', 'Mitotic cells (Lung)': '0.071', 'NK-cells (Lung)': '-0.266', 'B-cells (Lung)': '-0.296', 'Alpha cells': '0.270', 'Beta cells': '0.152', 'Prostate glandular cells': '0.764', 'Prostate basal glandular cells': '0.540', 'Urothelial cells': '0.205', 'Keratinocyte (other)': '0.510', 'Keratinocyte (granular)': '0.055', 'Hair cortex cells': '0.080', 'Inner root sheath cells': '0.131', 'Outer root sheath cells': '0.175', 'Sebaceous gland cells': '0.156', 'Eccrine sweat gland cells': '-0.207', 'Adipocytes (Skin)': '-0.244', 'Mitotic cells (Skin)': '0.442', 'Parietal cells': '0.654', 'Chief cells': '0.649', 'Gastric mucous cells': '0.781', 'Gastric enteroendocrine cells': '0.590', 'Mitotic cells (Stomach)': '0.445', 'Parafollicular cells': '0.173', 'Thyroid glandular cells': '0.865', 'Mitotic cells (Thyroid)': '-0.081', 'Adrenal cortex cells': '0.051', 'Adrenal medulla cells': '0.087', 'Mitotic cells (Adrenal gland)': '0.072', 'Minor salivary glandular cells': '0.371', 'Minor salivary gland ductal cells': '-0.142', 'Minor salivary gland basal cells': '0.582', 'Mitotic cells (Minor salivary gland)': '0.567', 'Adipocytes (Minor salivary gland)': '0.050', 'Somatotropes': '0.121', 'Lactotropes': '0.322', 'Gonadotropes': '0.330', 'Corticotropes': '0.180', 'Thyrotropes': '0.496', 'Undifferentiated cells (Pituitary gland)': '-0.108', 'Mitotic cells (Spleen)': '-0.228', 'Platelets': '-0.050', 'Erythrocytes': '-0.158', 'Hematopoietic stem cells': '-0.211', 'B-cells (Spleen)': '0.266', 'NK-cells (Spleen)': '0.309', 'Amygdala excitatory': '1.0', 'Cerebellar inhibitory': '0.9', 'Cge interneuron': '0.7', 'Deep-layer corticothalamic and 6b': '1.5', 'Deep-layer intratelencephalic': '0.7', 'Deep-layer near-projecting': '0.7', 'Eccentric medium spiny neuron': '0.6', 'Hippocampal ca1-3': '1.9', 'Hippocampal ca4': '1.2', 'Hippocampal dentate gyrus': '1.1', 'Lamp5-lhx6 and chandelier': '0.5', 'Lower rhombic lip': '0.8', 'Mammillary body': '0.6', 'Medium spiny neuron': '0.7', 'Mge interneuron': '1.7', 'Midbrain-derived inhibitory': '0.7', 'Miscellaneous': '0.9', 'Splatter': '3.8', 'Thalamic excitatory': '0.5', 'Upper rhombic lip': '0.8', 'Upper-layer intratelencephalic': '0.6', 'Astrocyte': '4.4', 'Bergmann glia': '0.2', 'Central nervous system macrophage': '0.6', 'Choroid plexus epithelial cell': '52.1', 'Committed oligodendrocyte precursor': '41.5', 'Ependymal cell': '4.8', 'Oligodendrocyte': '53.1', 'Oligodendrocyte precursor cell': '2.4', 'Endothelial cell': '0.7', 'Pericyte': '0.3', 'Vascular associated smooth muscle cell': '0.0', 'Fibroblast': '17.4', 'Leukocyte': '1.1', 'Basophil': '0.0', 'Eosinophil': '0.0', 'Neutrophil': '0.0', 'Classical monocyte': '0.0', 'Non-classical monocyte': '0.0', 'Intermediate monocyte': '0.0', 'T-reg': '2.3', 'GdT-cell': '0.0', 'MAIT T-cell': '0.0', 'Memory CD4 T-cell': '0.0', 'Naive CD4 T-cell': '0.1', 'Memory CD8 T-cell': '0.2', 'Naive CD8 T-cell': '0.3', 'Memory B-cell': '0.0', 'Naive B-cell': '0.1', 'Plasmacytoid DC': '46.6', 'Myeloid DC': '8.5', 'NK-cell': '0.1', 'Total PBMC': '0.7', 'Vd2 gdTCR': '0.0', 'Memory CD4 T-cell Th1\\/Th17': '0.1', 'Memory CD4 T-cell Th17': '0.2', 'Memory CD4 T-cell Th2': '2.9', 'Non-Vd2 gdTCR': '0.1', 'Memory CD4 T-cell Th1': '0.3', 'Memory CD4 T-cell TFH': '0.5', 'Terminal effector memory CD4 T-cell': '0.0', 'Central memory CD8 T-cell': '4.8', 'Effector memory CD8 T-cell': '0.0', 'Terminal effector memory CD8 T-cell': '0.6', 'Non-switched memory B-cell': '0.0', 'Plasmablast': '3.3', 'Switched memory B-cell': '0.0', 'Exhausted memory B-cell': '0.7', 'Progenitor cell': '2.3', 'Memory T-reg': '1.3', 'Naive CD4 T-cell activated': '0.3', 'Naive CD8 T-cell activated': '0.6', 'Naive T-reg': '0.1'}
1O6S, 2O72, 2OMT, 2OMU, 2OMV, 2OMX, 2OMY, 2OMZ, 3FF7, 3FF8, 3L6X, 3L6Y, 4ZT1, 4ZTE, 6CXY, 6OLE, 6OLF, 6OLG, 6VEL, 7STZ, 8H62
{'Adipose Tissue': 1.2125261088039867, 'Adrenal Gland': 0.1914223992248062, 'Bladder': 39.2033519047619, 'Blood': 1.340954264800861, 'Blood Vessel': 0.3121561692883895, 'Brain': 0.8550442199091597, 'Breast': 38.54918344226579, 'Cervix Uteri': 23.539115789473684, 'Colon': 43.41292142490372, 'Esophagus': 53.97513367404844, 'Fallopian Tube': 14.900277777777776, 'Heart': 0.119140469221835, 'Kidney': 25.040449438202245, 'Liver': 26.60802654867257, 'Lung': 35.447986366782004, 'Muscle': 0.1378936151930261, 'Nerve': 17.518468982229404, 'Ovary': 3.6515122222222223, 'Pancreas': 56.89676829268293, 'Pituitary': 24.68741660777385, 'Prostate': 61.279967346938776, 'Salivary Gland': 92.01685185185184, 'Skin': 79.77571720232172, 'Small Intestine': 71.7519320855615, 'Spleen': 10.061029045643156, 'Stomach': 58.07813805013927, 'Testis': 0.8144204986149585, 'Thyroid': 135.176797856049, 'Uterus': 1.442593943661972, 'Vagina': 86.52345512820513}
PIMREG
MASRWQNMGTSVRRRSLQHQEQLEDSKELQPVVSHQETSVGALGSLCRQFQRRLPLRAVNLNLRAGPSWKRLETPEPGQQGLQAAARSAKSALGAVSQRIQESCQSGTKWLVETQVKARRRKRGAQKGSGSPTHSLSQKSTRLSGAAPAHSAADPWEKEHHRLSVRMGSHAHPLRRSRREAAFRSPYSSTEPLCSPSESDSDLEPVGAGIQHLQKLSQELDEAIMAEESGDIVSLIHD
Homo sapiens
null
Not found
{}
null
{}
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0.76, 0.55, 0.31, 0.94, 0.22, 0.57, 0.17, 0.4, 0.07, 0.5, 0.31, 0.7, 0.2, 0.14, 0.3, 0.23, 0.58, 0.07, 0.06, 0.55, 0.15, 0.46, 0.43, 0.64, 0.53, 0.0, 0.18, 0.01, 0.23, 0.02, 0.63, 0.33, 0.79, 0.06, 0.38, 0.07, 0.14, 0.23, 0.68, 0.89, 0.29, 0.06, 0.72, 0.92, 0.24, 0.25, 0.0, 0.46, 0.02, 0.21, 0.01, 0.06, 0.0, 0.05, 0.07, 0.61, 0.17, 0.89, 0.72, 0.66, 0.14, 0.52, 0.07, 0.58, 0.01, 0.26, 0.0, 0.13, 0.0, 0.29, 0.04, 0.46, 0.27, 0.28, 0.23, 0.56, 0.32, 0.25, 0.0, 0.33, 0.05, 0.55, 0.5, 0.58, 0.53, 0.04, 0.27, 0.02, 0.04, 0.37, 0.67, 0.74, 0.35, 0.62, 0.54, 0.26, 0.46, 0.0, 0.47, 0.09, 0.45, 0.15, 0.39, 0.05, 0.44, 0.85, 0.56, 0.11, 0.11, 0.35, 0.42, 0.03, 0.32, 0.12, 0.49, 0.19, 0.25, 0.8, 0.6, 0.09, 0.49, 0.57, 0.36, 0.04, 0.35, 0.28, 0.52, 0.39, 0.5, 0.28, 0.93, 0.47, 0.3, 0.47, 0.08, 0.02, 0.18, 0.01, 0.34, 0.23, 0.55, 0.57, 0.91, 0.1, 0.78, 0.52, 0.34, 0.61, 0.24, 0.75, 0.0, 0.2, 0.02, 0.24, 0.0, 0.18, 0.04, 0.44, 0.59, 0.71, 0.29, 0.52, 0.37, 0.5, 0.11, 0.6, 0.02, 0.48, 0.01, 0.16, 0.04, 0.35, 0.66, 0.47, 0.74, 0.14, 0.62, 0.16, 0.77, 0.79, 0.27, 0.93, 0.69, 0.88, 0.88, 0.85, 0.87, 0.91, 0.92, 0.82, 0.63, 0.75, 0.7, 0.7, 0.38, 0.43, 0.64, 0.55, 0.54, 0.59, 0.45, 0.47, 0.5, 0.58, 0.52, 0.61, 0.57, 0.52, 0.68, 0.44, 0.6, 0.61, 0.58, 0.55, 0.5, 0.61, 0.61, 0.86, 0.86, 0.75, 0.91, 0.96, 0.93, 1.0, 0.87, 0.97, 0.91, 0.95, 0.86, 0.98, 0.93, 0.88, 0.59, 0.87, 0.7, 0.67, 0.85, 0.89, 0.88, 0.91, 0.93, 0.88, 0.99, 0.92, 1.0, 0.79, 0.9, 1.0, 0.94, 1.0, 0.97, 0.96, 0.9, 0.63, 0.68, 0.48, 0.54, 0.8, 0.7, 0.7, 0.95, 0.87, 0.77, 0.84, 0.79, 0.89, 0.95, 0.8, 0.77, 0.51, 0.87, 0.7, 0.52, 0.84, 0.91, 0.51, 0.96, 0.79, 0.92, 0.84, 0.21, 0.89, 0.53, 0.52, 0.89, 0.86, 0.26, 0.91, 0.45, 0.68, 0.84, 0.48, 0.44, 0.51, 0.62, 0.28, 0.59, 0.63, 0.57, 0.15, 0.55, 0.66, 0.1, 0.38, 0.74, 0.65, 0.17, 0.43, 0.66, 0.41, 0.8, 0.75, 0.9, 0.93, 0.52, 0.76, 0.89, 0.87, 0.76, 0.92, 0.91, 0.75, 0.61, 0.96, 0.89, 0.73, 0.97, 0.68, 0.87, 0.55, 0.85, 0.77, 0.69, 0.76, 0.98, 0.83, 0.68, 0.82, 0.74, 0.65, 0.96, 0.93, 0.54, 0.64, 0.28, 0.54, 0.52, 0.16, 0.51, 0.88, 0.6, 0.4, 0.88, 0.95, 0.33, 0.56, 0.73, 0.39, 0.06, 0.61, 0.75, 0.47, 0.19, 0.87, 0.7, 0.97, 0.94, 0.97]
null
null
null
Component of an E-cadherin/ catenin adhesion complex composed of at least E-cadherin/CDH1, beta-catenin/CTNNB1 or gamma-catenin/JUP, and potentially alpha-catenin/CTNNA1. Forms a ternary complex composed of ADAM10, CADH1 and EPHA4,
null
null
KLRG1, SPEF1, DLGAP5, AJAP1, RAPGEF2, RAB8B, PIP5K1C, PKP2, TRPV4, CTNNB1, CAV1, DDR1, TBC1D2, CTNNA1, JUP, CTNND1, PSEN1, LIMA1, CDH1, JUP, ADAM10, CADH1 , EPHA4,
null
null
null
null
Homodimer
null
79.91949
0.474025
null
null
2,603
P12830
Q9BW19
null
degron_data
CDH1
MGPWSRSLSALLLLLQVSSWLCQEPEPCHPGFDAESYTFTVPRRHLERGRVLGRVNFEDCTGRQRTAYFSLDTRFKVGTDGVITVKRPLRFHNPQIHFLVYAWDSTYRKFSTKVTLNTVGHHHRPPPHQASVSGIQAELLTFPNSSPGLRRQKRDWVIPPISCPENEKGPFPKNLVQIKSNKDKEGKVFYSITGQGADTPPVGVFIIERETGWLKVTEPLDRERIATYTLFSHAVSSNGNAVEDPMEILITVTDQNDNKPEFTQEVFKGSVMEGALPGTSVMEVTATDADDDVNTYNAAIAYTILSQDPELPDKNMFTINRNTGVISVVTTGLDRESFPTYTLVVQAADLQGEGLSTTATAVITVTDTNDNPPIFNPTTYKGQVPENEANVVITTLKVTDADAPNTPAWEAVYTILNDDGGQFVVTTNPVNNDGILKTAKGLDFEAKQQYILHVAVTNVVPFEVSLTTSTATVTVDVLDVNEAPIFVPPEKRVEVSEDFGVGQEITSYTAQEPDTFMEQKITYRIWRDTANWLEINPDTGAISTRAELDREDFEHVKNSTYTALIIATDNGSPVATGTGTLLLILSDVNDNAPIPEPRTIFFCERNPKPQVINIIDADLPPNTSPFTAELTHGASANWTIQYNDPTQESIILKPKMALEVGDYKINLKLMDNQNKDQVTTLEVSVCDCEGAAGVCRKAQPVEAGLQIPAILGILGGILALLILILLLLLFLRRRAVVKEPLLPPEDDTRDNVYYYDEEGGGEEDQDFDLSQLHRGLDARPEVTRNDVAPTLMSVPRYLPRPANPDEIGNFIDENLKAADTDPTAPPYDSLLVFDYEGSGSEAASLSSLNSSESDKDQDYDYLNEWGNRFKKLADMYGGGEDD
Homo sapiens
Cell junction, adherens junction, Cell membrane, Endosome, Golgi apparatus, trans-Golgi network, Cytoplasm, Cell junction, desmosome
Tissue enhanced (parathyroid)
{'Ciliated cells': '119.1', 'Basal respiratory cells': '71.1', 'Club cells': '97.3', 'Ionocytes': '81.0', 'Mucus glandular cells': '155.0', 'Serous glandular cells': '67.8', 'Gastric mucus-secreting cells': '133.2', 'Proximal enterocytes': '140.9', 'Paneth cells': '125.1', 'Distal enterocytes': '307.5', 'Intestinal goblet cells': '173.5', 'Exocrine glandular cells': '-0.605', 'Basal prostatic cells': '68.3', 'Prostatic glandular cells': '186.7', 'Breast glandular cells': '0.773', 'Breast myoepithelial cells': '0.700', 'Glandular and luminal cells': '313.0', 'Secretory cells': '82.3', 'Basal keratinocytes': '102.5', 'Suprabasal keratinocytes': '162.6', 'Basal squamous epithelial cells': '51.0', 'Squamous epithelial cells': '106.9', 'Alveolar cells type 1': '0.437', 'Alveolar cells type 2': '0.706', 'Salivary duct cells': '95.9', 'Ductal cells': '0.541', 'Hepatocytes': '0.600', 'Cholangiocytes': '129.7', 'Proximal tubular cells': '0.042', 'Distal tubular cells': '0.0', 'Collecting duct cells': '143.9', 'Mesothelial cells': '0.799', 'Sertoli cells': '0.252', 'Granulosa cells': '12.9', 'Enteroendocrine cells': '92.4', 'Pancreatic endocrine cells': '78.1', 'Leydig cells': '0.264', 'Excitatory neurons': '0.7', 'Inhibitory neurons': '1.3', 'Cone photoreceptor cells': '0.0', 'Rod photoreceptor cells': '0.0', 'Bipolar cells': '0.2', 'Horizontal cells': '0.6', 'Astrocytes': '0.6', 'Oligodendrocyte precursor cells': '0.5', 'Oligodendrocytes': '29.9', 'Microglial cells': '0.9', 'Muller glia cells': '0.1', 'Schwann cells': '0.131', 'Spermatogonia': '0.392', 'Spermatocytes': '0.193', 'Early spermatids': '-0.217', 'Late spermatids': '-0.290', 'Oocytes': '16.9', 'Cytotrophoblasts': '119.2', 'Syncytiotrophoblasts': '45.0', 'Extravillous trophoblasts': '24.9', 'Endothelial cells': '6.1', 'Lymphatic endothelial cells': '0.4', 'Cardiomyocytes': '0.135', 'Skeletal myocytes': '0.107', 'Smooth muscle cells': '5.8', 'Adipocytes': '2.1', 'Melanocytes': '0.335', 'Fibroblasts': '6.5', 'Peritubular cells': '0.210', 'Endometrial stromal cells': '27.7', 'Ovarian stromal cells': '0.7', 'Undifferentiated cells': '101.6', 'T-cells': '2.9', 'B-cells': '4.4', 'Plasma cells': '6.1', 'Nk-cells': '0.0', 'Granulocytes': '8.4', 'Monocytes': '0.0', 'Macrophages': '6.0', 'Hofbauer cells': '4.3', 'Kupffer cells': '1.0', 'Dendritic cells': '5.9', 'Langerhans cells': '0.304', 'Erythroid cells': '0.036', 'Adipocytes (Subcutaneous)': '-0.081', 'Adipocytes (Visceral)': '-0.209', 'Breast glandular cells (progenitors)': '0.538', 'Adipocytes (Breast)': '-0.689', 'Colon enterocytes': '0.790', 'Colon enteroendocrine cells': '0.112', 'Enteric glia cells': '-0.048', 'Mitotic cells (Colon)': '0.299', 'Mitotic cells (Heart)': '0.120', 'Podocytes': '-0.118', 'Ascending Loop of Henle cells': '0.475', 'Intercalated cells': '0.212', 'Cholangiocyte': '0.090', 'NK-cells (Liver)': '-0.005', 'Respiratory ciliated cells': '-0.012', 'Mitotic cells (Lung)': '0.071', 'NK-cells (Lung)': '-0.266', 'B-cells (Lung)': '-0.296', 'Alpha cells': '0.270', 'Beta cells': '0.152', 'Prostate glandular cells': '0.764', 'Prostate basal glandular cells': '0.540', 'Urothelial cells': '0.205', 'Keratinocyte (other)': '0.510', 'Keratinocyte (granular)': '0.055', 'Hair cortex cells': '0.080', 'Inner root sheath cells': '0.131', 'Outer root sheath cells': '0.175', 'Sebaceous gland cells': '0.156', 'Eccrine sweat gland cells': '-0.207', 'Adipocytes (Skin)': '-0.244', 'Mitotic cells (Skin)': '0.442', 'Parietal cells': '0.654', 'Chief cells': '0.649', 'Gastric mucous cells': '0.781', 'Gastric enteroendocrine cells': '0.590', 'Mitotic cells (Stomach)': '0.445', 'Parafollicular cells': '0.173', 'Thyroid glandular cells': '0.865', 'Mitotic cells (Thyroid)': '-0.081', 'Adrenal cortex cells': '0.051', 'Adrenal medulla cells': '0.087', 'Mitotic cells (Adrenal gland)': '0.072', 'Minor salivary glandular cells': '0.371', 'Minor salivary gland ductal cells': '-0.142', 'Minor salivary gland basal cells': '0.582', 'Mitotic cells (Minor salivary gland)': '0.567', 'Adipocytes (Minor salivary gland)': '0.050', 'Somatotropes': '0.121', 'Lactotropes': '0.322', 'Gonadotropes': '0.330', 'Corticotropes': '0.180', 'Thyrotropes': '0.496', 'Undifferentiated cells (Pituitary gland)': '-0.108', 'Mitotic cells (Spleen)': '-0.228', 'Platelets': '-0.050', 'Erythrocytes': '-0.158', 'Hematopoietic stem cells': '-0.211', 'B-cells (Spleen)': '0.266', 'NK-cells (Spleen)': '0.309', 'Amygdala excitatory': '1.0', 'Cerebellar inhibitory': '0.9', 'Cge interneuron': '0.7', 'Deep-layer corticothalamic and 6b': '1.5', 'Deep-layer intratelencephalic': '0.7', 'Deep-layer near-projecting': '0.7', 'Eccentric medium spiny neuron': '0.6', 'Hippocampal ca1-3': '1.9', 'Hippocampal ca4': '1.2', 'Hippocampal dentate gyrus': '1.1', 'Lamp5-lhx6 and chandelier': '0.5', 'Lower rhombic lip': '0.8', 'Mammillary body': '0.6', 'Medium spiny neuron': '0.7', 'Mge interneuron': '1.7', 'Midbrain-derived inhibitory': '0.7', 'Miscellaneous': '0.9', 'Splatter': '3.8', 'Thalamic excitatory': '0.5', 'Upper rhombic lip': '0.8', 'Upper-layer intratelencephalic': '0.6', 'Astrocyte': '4.4', 'Bergmann glia': '0.2', 'Central nervous system macrophage': '0.6', 'Choroid plexus epithelial cell': '52.1', 'Committed oligodendrocyte precursor': '41.5', 'Ependymal cell': '4.8', 'Oligodendrocyte': '53.1', 'Oligodendrocyte precursor cell': '2.4', 'Endothelial cell': '0.7', 'Pericyte': '0.3', 'Vascular associated smooth muscle cell': '0.0', 'Fibroblast': '17.4', 'Leukocyte': '1.1', 'Basophil': '0.0', 'Eosinophil': '0.0', 'Neutrophil': '0.0', 'Classical monocyte': '0.0', 'Non-classical monocyte': '0.0', 'Intermediate monocyte': '0.0', 'T-reg': '2.3', 'GdT-cell': '0.0', 'MAIT T-cell': '0.0', 'Memory CD4 T-cell': '0.0', 'Naive CD4 T-cell': '0.1', 'Memory CD8 T-cell': '0.2', 'Naive CD8 T-cell': '0.3', 'Memory B-cell': '0.0', 'Naive B-cell': '0.1', 'Plasmacytoid DC': '46.6', 'Myeloid DC': '8.5', 'NK-cell': '0.1', 'Total PBMC': '0.7', 'Vd2 gdTCR': '0.0', 'Memory CD4 T-cell Th1\\/Th17': '0.1', 'Memory CD4 T-cell Th17': '0.2', 'Memory CD4 T-cell Th2': '2.9', 'Non-Vd2 gdTCR': '0.1', 'Memory CD4 T-cell Th1': '0.3', 'Memory CD4 T-cell TFH': '0.5', 'Terminal effector memory CD4 T-cell': '0.0', 'Central memory CD8 T-cell': '4.8', 'Effector memory CD8 T-cell': '0.0', 'Terminal effector memory CD8 T-cell': '0.6', 'Non-switched memory B-cell': '0.0', 'Plasmablast': '3.3', 'Switched memory B-cell': '0.0', 'Exhausted memory B-cell': '0.7', 'Progenitor cell': '2.3', 'Memory T-reg': '1.3', 'Naive CD4 T-cell activated': '0.3', 'Naive CD8 T-cell activated': '0.6', 'Naive T-reg': '0.1'}
1O6S, 2O72, 2OMT, 2OMU, 2OMV, 2OMX, 2OMY, 2OMZ, 3FF7, 3FF8, 3L6X, 3L6Y, 4ZT1, 4ZTE, 6CXY, 6OLE, 6OLF, 6OLG, 6VEL, 7STZ, 8H62
{'Adipose Tissue': 1.2125261088039867, 'Adrenal Gland': 0.1914223992248062, 'Bladder': 39.2033519047619, 'Blood': 1.340954264800861, 'Blood Vessel': 0.3121561692883895, 'Brain': 0.8550442199091597, 'Breast': 38.54918344226579, 'Cervix Uteri': 23.539115789473684, 'Colon': 43.41292142490372, 'Esophagus': 53.97513367404844, 'Fallopian Tube': 14.900277777777776, 'Heart': 0.119140469221835, 'Kidney': 25.040449438202245, 'Liver': 26.60802654867257, 'Lung': 35.447986366782004, 'Muscle': 0.1378936151930261, 'Nerve': 17.518468982229404, 'Ovary': 3.6515122222222223, 'Pancreas': 56.89676829268293, 'Pituitary': 24.68741660777385, 'Prostate': 61.279967346938776, 'Salivary Gland': 92.01685185185184, 'Skin': 79.77571720232172, 'Small Intestine': 71.7519320855615, 'Spleen': 10.061029045643156, 'Stomach': 58.07813805013927, 'Testis': 0.8144204986149585, 'Thyroid': 135.176797856049, 'Uterus': 1.442593943661972, 'Vagina': 86.52345512820513}
KIFC1
MDPQRSPLLEVKGNIELKRPLIKAPSQLPLSGSRLKRRPDQMEDGLEPEKKRTRGLGATTKITTSHPRVPSLTTVPQTQGQTTAQKVSKKTGPRCSTAIATGLKNQKPVPAVPVQKSGTSGVPPMAGGKKPSKRPAWDLKGQLCDLNAELKRCRERTQTLDQENQQLQDQLRDAQQQVKALGTERTTLEGHLAKVQAQAEQGQQELKNLRACVLELEERLSTQEGLVQELQKKQVELQEERRGLMSQLEEKERRLQTSEAALSSSQAEVASLRQETVAQAALLTEREERLHGLEMERRRLHNQLQELKGNIRVFCRVRPVLPGEPTPPPGLLLFPSGPGGPSDPPTRLSLSRSDERRGTLSGAPAPPTRHDFSFDRVFPPGSGQDEVFEEIAMLVQSALDGYPVCIFAYGQTGSGKTFTMEGGPGGDPQLEGLIPRALRHLFSVAQELSGQGWTYSFVASYVEIYNETVRDLLATGTRKGQGGECEIRRAGPGSEELTVTNARYVPVSCEKEVDALLHLARQNRAVARTAQNERSSRSHSVFQLQISGEHSSRGLQCGAPLSLVDLAGSERLDPGLALGPGERERLRETQAINSSLSTLGLVIMALSNKESHVPYRNSKLTYLLQNSLGGSAKMLMFVNISPLEENVSESLNSLRFASKVNQCVIGTAQANRK
Homo sapiens
Nucleus, Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, Cytoplasm, cytoskeleton, spindle, Early endosome
Tissue enhanced (bone marrow, lymphoid tissue)
{'Ciliated cells': '1.4', 'Basal respiratory cells': '4.1', 'Club cells': '1.6', 'Ionocytes': '1.1', 'Mucus glandular cells': '1.2', 'Serous glandular cells': '2.4', 'Gastric mucus-secreting cells': '4.7', 'Proximal enterocytes': '0.4', 'Paneth cells': '1.6', 'Distal enterocytes': '1.8', 'Intestinal goblet cells': '5.2', 'Exocrine glandular cells': '-0.392', 'Basal prostatic cells': '0.2', 'Prostatic glandular cells': '0.1', 'Breast glandular cells': '0.654', 'Breast myoepithelial cells': '0.451', 'Glandular and luminal cells': '6.0', 'Secretory cells': '0.6', 'Basal keratinocytes': '7.7', 'Suprabasal keratinocytes': '2.9', 'Basal squamous epithelial cells': '5.1', 'Squamous epithelial cells': '12.9', 'Alveolar cells type 1': '-0.038', 'Alveolar cells type 2': '0.161', 'Salivary duct cells': '1.0', 'Ductal cells': '0.487', 'Hepatocytes': '0.340', 'Cholangiocytes': '0.0', 'Proximal tubular cells': '0.214', 'Distal tubular cells': '0.0', 'Collecting duct cells': '0.0', 'Mesothelial cells': '0.193', 'Sertoli cells': '-0.131', 'Granulosa cells': '3.7', 'Enteroendocrine cells': '1.8', 'Pancreatic endocrine cells': '1.7', 'Leydig cells': '-0.188', 'Excitatory neurons': '0.3', 'Inhibitory neurons': '0.3', 'Cone photoreceptor cells': '0.0', 'Rod photoreceptor cells': '0.4', 'Bipolar cells': '0.2', 'Horizontal cells': '0.0', 'Astrocytes': '0.9', 'Oligodendrocyte precursor cells': '0.9', 'Oligodendrocytes': '0.6', 'Microglial cells': '0.9', 'Muller glia cells': '0.5', 'Schwann cells': '0.104', 'Spermatogonia': '0.251', 'Spermatocytes': '0.674', 'Early spermatids': '0.303', 'Late spermatids': '0.214', 'Oocytes': '22.1', 'Cytotrophoblasts': '16.6', 'Syncytiotrophoblasts': '3.3', 'Extravillous trophoblasts': '37.6', 'Endothelial cells': '1.2', 'Lymphatic endothelial cells': '0.0', 'Cardiomyocytes': '0.332', 'Skeletal myocytes': '-0.017', 'Smooth muscle cells': '1.4', 'Adipocytes': '0.4', 'Melanocytes': '0.432', 'Fibroblasts': '2.8', 'Peritubular cells': '-0.230', 'Endometrial stromal cells': '1.3', 'Ovarian stromal cells': '1.8', 'Undifferentiated cells': '21.1', 'T-cells': '4.6', 'B-cells': '3.0', 'Plasma cells': '17.0', 'Nk-cells': '1.8', 'Granulocytes': '1.0', 'Monocytes': '4.1', 'Macrophages': '4.6', 'Hofbauer cells': '9.7', 'Kupffer cells': '1.8', 'Dendritic cells': '3.2', 'Langerhans cells': '0.202', 'Erythroid cells': '0.106', 'Adipocytes (Subcutaneous)': '-0.206', 'Adipocytes (Visceral)': '-0.112', 'Breast glandular cells (progenitors)': '0.385', 'Adipocytes (Breast)': '-0.441', 'Colon enterocytes': '0.333', 'Colon enteroendocrine cells': '-0.118', 'Enteric glia cells': '-0.195', 'Mitotic cells (Colon)': '0.651', 'Mitotic cells (Heart)': '0.890', 'Podocytes': '-0.166', 'Ascending Loop of Henle cells': '0.362', 'Intercalated cells': '-0.031', 'Cholangiocyte': '0.357', 'NK-cells (Liver)': '-0.092', 'Respiratory ciliated cells': '0.008', 'Mitotic cells (Lung)': '0.808', 'NK-cells (Lung)': '0.017', 'B-cells (Lung)': '0.060', 'Alpha cells': '0.209', 'Beta cells': '0.053', 'Prostate glandular cells': '0.296', 'Prostate basal glandular cells': '0.287', 'Urothelial cells': '0.164', 'Keratinocyte (other)': '0.228', 'Keratinocyte (granular)': '-0.190', 'Hair cortex cells': '0.103', 'Inner root sheath cells': '0.213', 'Outer root sheath cells': '0.266', 'Sebaceous gland cells': '0.124', 'Eccrine sweat gland cells': '0.078', 'Adipocytes (Skin)': '-0.096', 'Mitotic cells (Skin)': '0.927', 'Parietal cells': '0.105', 'Chief cells': '0.059', 'Gastric mucous cells': '0.548', 'Gastric enteroendocrine cells': '0.168', 'Mitotic cells (Stomach)': '0.958', 'Parafollicular cells': '0.061', 'Thyroid glandular cells': '0.142', 'Mitotic cells (Thyroid)': '0.634', 'Adrenal cortex cells': '0.411', 'Adrenal medulla cells': '0.112', 'Mitotic cells (Adrenal gland)': '0.896', 'Minor salivary glandular cells': '0.146', 'Minor salivary gland ductal cells': '-0.299', 'Minor salivary gland basal cells': '0.691', 'Mitotic cells (Minor salivary gland)': '0.959', 'Adipocytes (Minor salivary gland)': '0.168', 'Somatotropes': '-0.048', 'Lactotropes': '-0.123', 'Gonadotropes': '0.021', 'Corticotropes': '-0.117', 'Thyrotropes': '-0.025', 'Undifferentiated cells (Pituitary gland)': '0.213', 'Mitotic cells (Spleen)': '0.933', 'Platelets': '0.193', 'Erythrocytes': '0.300', 'Hematopoietic stem cells': '0.414', 'B-cells (Spleen)': '-0.134', 'NK-cells (Spleen)': '-0.243', 'Amygdala excitatory': '0.3', 'Cerebellar inhibitory': '0.2', 'Cge interneuron': '0.2', 'Deep-layer corticothalamic and 6b': '0.5', 'Deep-layer intratelencephalic': '0.3', 'Deep-layer near-projecting': '0.6', 'Eccentric medium spiny neuron': '0.3', 'Hippocampal ca1-3': '0.3', 'Hippocampal ca4': '0.7', 'Hippocampal dentate gyrus': '0.2', 'Lamp5-lhx6 and chandelier': '0.2', 'Lower rhombic lip': '0.8', 'Mammillary body': '0.2', 'Medium spiny neuron': '0.4', 'Mge interneuron': '0.3', 'Midbrain-derived inhibitory': '0.1', 'Miscellaneous': '0.3', 'Splatter': '0.3', 'Thalamic excitatory': '0.1', 'Upper rhombic lip': '0.1', 'Upper-layer intratelencephalic': '0.3', 'Astrocyte': '0.4', 'Bergmann glia': '0.8', 'Central nervous system macrophage': '1.0', 'Choroid plexus epithelial cell': '0.2', 'Committed oligodendrocyte precursor': '0.3', 'Ependymal cell': '0.3', 'Oligodendrocyte': '0.6', 'Oligodendrocyte precursor cell': '0.6', 'Endothelial cell': '0.7', 'Pericyte': '0.1', 'Vascular associated smooth muscle cell': '1.1', 'Fibroblast': '2.8', 'Leukocyte': '1.5', 'Basophil': '2.1', 'Eosinophil': '0.0', 'Neutrophil': '0.5', 'Classical monocyte': '0.7', 'Non-classical monocyte': '0.8', 'Intermediate monocyte': '1.5', 'T-reg': '7.8', 'GdT-cell': '0.1', 'MAIT T-cell': '0.1', 'Memory CD4 T-cell': '0.1', 'Naive CD4 T-cell': '0.4', 'Memory CD8 T-cell': '0.6', 'Naive CD8 T-cell': '0.4', 'Memory B-cell': '0.2', 'Naive B-cell': '0.2', 'Plasmacytoid DC': '0.1', 'Myeloid DC': '2.9', 'NK-cell': '2.1', 'Total PBMC': '4.4', 'Vd2 gdTCR': '1.2', 'Memory CD4 T-cell Th1\\/Th17': '0.4', 'Memory CD4 T-cell Th17': '1.1', 'Memory CD4 T-cell Th2': '1.3', 'Non-Vd2 gdTCR': '1.8', 'Memory CD4 T-cell Th1': '1.6', 'Memory CD4 T-cell TFH': '1.2', 'Terminal effector memory CD4 T-cell': '1.1', 'Central memory CD8 T-cell': '3.2', 'Effector memory CD8 T-cell': '7.3', 'Terminal effector memory CD8 T-cell': '2.5', 'Non-switched memory B-cell': '1.3', 'Plasmablast': '54.0', 'Switched memory B-cell': '3.1', 'Exhausted memory B-cell': '6.8', 'Progenitor cell': '0.7', 'Memory T-reg': '5.4', 'Naive CD4 T-cell activated': '0.7', 'Naive CD8 T-cell activated': '1.2', 'Naive T-reg': '0.7'}
5WDH
{'Adipose Tissue': 1.382284941860465, 'Adrenal Gland': 1.4082185271317829, 'Bladder': 1.3421190476190477, 'Blood': 18.739540075349836, 'Blood Vessel': 0.8594463071161049, 'Brain': 0.2872865174110522, 'Breast': 4.053933877995643, 'Cervix Uteri': 2.545968421052631, 'Colon': 3.6692371245186135, 'Esophagus': 6.165866844290657, 'Fallopian Tube': 1.5988444444444443, 'Heart': 0.3875638722415795, 'Kidney': 0.8146791011235954, 'Liver': 0.7714212389380531, 'Lung': 4.1580712802768165, 'Muscle': 0.173771603985056, 'Nerve': 1.0527096930533115, 'Ovary': 3.627610555555556, 'Pancreas': 0.416666219512195, 'Pituitary': 1.0019238869257951, 'Prostate': 1.616406, 'Salivary Gland': 2.916056790123457, 'Skin': 16.427071752349367, 'Small Intestine': 7.408389304812834, 'Spleen': 7.606529460580913, 'Stomach': 3.543790445682451, 'Testis': 25.981939058171744, 'Thyroid': 1.4404921898928025, 'Uterus': 1.7768323943661972, 'Vagina': 6.082370512820512}
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null
Component of an E-cadherin/ catenin adhesion complex composed of at least E-cadherin/CDH1, beta-catenin/CTNNB1 or gamma-catenin/JUP, and potentially alpha-catenin/CTNNA1. Forms a ternary complex composed of ADAM10, CADH1 and EPHA4,
null
null
KLRG1, SPEF1, DLGAP5, AJAP1, RAPGEF2, RAB8B, PIP5K1C, PKP2, TRPV4, CTNNB1, CAV1, DDR1, TBC1D2, CTNNA1, JUP, CTNND1, PSEN1, LIMA1, CDH1, JUP, ADAM10, CADH1 , EPHA4,
null
null
null
null
Homodimer
null
79.91949
0.474025
77.361605
0.49159
1,075
P12830
Q9BXS6
null
degron_data
CDH1
MGPWSRSLSALLLLLQVSSWLCQEPEPCHPGFDAESYTFTVPRRHLERGRVLGRVNFEDCTGRQRTAYFSLDTRFKVGTDGVITVKRPLRFHNPQIHFLVYAWDSTYRKFSTKVTLNTVGHHHRPPPHQASVSGIQAELLTFPNSSPGLRRQKRDWVIPPISCPENEKGPFPKNLVQIKSNKDKEGKVFYSITGQGADTPPVGVFIIERETGWLKVTEPLDRERIATYTLFSHAVSSNGNAVEDPMEILITVTDQNDNKPEFTQEVFKGSVMEGALPGTSVMEVTATDADDDVNTYNAAIAYTILSQDPELPDKNMFTINRNTGVISVVTTGLDRESFPTYTLVVQAADLQGEGLSTTATAVITVTDTNDNPPIFNPTTYKGQVPENEANVVITTLKVTDADAPNTPAWEAVYTILNDDGGQFVVTTNPVNNDGILKTAKGLDFEAKQQYILHVAVTNVVPFEVSLTTSTATVTVDVLDVNEAPIFVPPEKRVEVSEDFGVGQEITSYTAQEPDTFMEQKITYRIWRDTANWLEINPDTGAISTRAELDREDFEHVKNSTYTALIIATDNGSPVATGTGTLLLILSDVNDNAPIPEPRTIFFCERNPKPQVINIIDADLPPNTSPFTAELTHGASANWTIQYNDPTQESIILKPKMALEVGDYKINLKLMDNQNKDQVTTLEVSVCDCEGAAGVCRKAQPVEAGLQIPAILGILGGILALLILILLLLLFLRRRAVVKEPLLPPEDDTRDNVYYYDEEGGGEEDQDFDLSQLHRGLDARPEVTRNDVAPTLMSVPRYLPRPANPDEIGNFIDENLKAADTDPTAPPYDSLLVFDYEGSGSEAASLSSLNSSESDKDQDYDYLNEWGNRFKKLADMYGGGEDD
Homo sapiens
Cell junction, adherens junction, Cell membrane, Endosome, Golgi apparatus, trans-Golgi network, Cytoplasm, Cell junction, desmosome
Tissue enhanced (parathyroid)
{'Ciliated cells': '119.1', 'Basal respiratory cells': '71.1', 'Club cells': '97.3', 'Ionocytes': '81.0', 'Mucus glandular cells': '155.0', 'Serous glandular cells': '67.8', 'Gastric mucus-secreting cells': '133.2', 'Proximal enterocytes': '140.9', 'Paneth cells': '125.1', 'Distal enterocytes': '307.5', 'Intestinal goblet cells': '173.5', 'Exocrine glandular cells': '-0.605', 'Basal prostatic cells': '68.3', 'Prostatic glandular cells': '186.7', 'Breast glandular cells': '0.773', 'Breast myoepithelial cells': '0.700', 'Glandular and luminal cells': '313.0', 'Secretory cells': '82.3', 'Basal keratinocytes': '102.5', 'Suprabasal keratinocytes': '162.6', 'Basal squamous epithelial cells': '51.0', 'Squamous epithelial cells': '106.9', 'Alveolar cells type 1': '0.437', 'Alveolar cells type 2': '0.706', 'Salivary duct cells': '95.9', 'Ductal cells': '0.541', 'Hepatocytes': '0.600', 'Cholangiocytes': '129.7', 'Proximal tubular cells': '0.042', 'Distal tubular cells': '0.0', 'Collecting duct cells': '143.9', 'Mesothelial cells': '0.799', 'Sertoli cells': '0.252', 'Granulosa cells': '12.9', 'Enteroendocrine cells': '92.4', 'Pancreatic endocrine cells': '78.1', 'Leydig cells': '0.264', 'Excitatory neurons': '0.7', 'Inhibitory neurons': '1.3', 'Cone photoreceptor cells': '0.0', 'Rod photoreceptor cells': '0.0', 'Bipolar cells': '0.2', 'Horizontal cells': '0.6', 'Astrocytes': '0.6', 'Oligodendrocyte precursor cells': '0.5', 'Oligodendrocytes': '29.9', 'Microglial cells': '0.9', 'Muller glia cells': '0.1', 'Schwann cells': '0.131', 'Spermatogonia': '0.392', 'Spermatocytes': '0.193', 'Early spermatids': '-0.217', 'Late spermatids': '-0.290', 'Oocytes': '16.9', 'Cytotrophoblasts': '119.2', 'Syncytiotrophoblasts': '45.0', 'Extravillous trophoblasts': '24.9', 'Endothelial cells': '6.1', 'Lymphatic endothelial cells': '0.4', 'Cardiomyocytes': '0.135', 'Skeletal myocytes': '0.107', 'Smooth muscle cells': '5.8', 'Adipocytes': '2.1', 'Melanocytes': '0.335', 'Fibroblasts': '6.5', 'Peritubular cells': '0.210', 'Endometrial stromal cells': '27.7', 'Ovarian stromal cells': '0.7', 'Undifferentiated cells': '101.6', 'T-cells': '2.9', 'B-cells': '4.4', 'Plasma cells': '6.1', 'Nk-cells': '0.0', 'Granulocytes': '8.4', 'Monocytes': '0.0', 'Macrophages': '6.0', 'Hofbauer cells': '4.3', 'Kupffer cells': '1.0', 'Dendritic cells': '5.9', 'Langerhans cells': '0.304', 'Erythroid cells': '0.036', 'Adipocytes (Subcutaneous)': '-0.081', 'Adipocytes (Visceral)': '-0.209', 'Breast glandular cells (progenitors)': '0.538', 'Adipocytes (Breast)': '-0.689', 'Colon enterocytes': '0.790', 'Colon enteroendocrine cells': '0.112', 'Enteric glia cells': '-0.048', 'Mitotic cells (Colon)': '0.299', 'Mitotic cells (Heart)': '0.120', 'Podocytes': '-0.118', 'Ascending Loop of Henle cells': '0.475', 'Intercalated cells': '0.212', 'Cholangiocyte': '0.090', 'NK-cells (Liver)': '-0.005', 'Respiratory ciliated cells': '-0.012', 'Mitotic cells (Lung)': '0.071', 'NK-cells (Lung)': '-0.266', 'B-cells (Lung)': '-0.296', 'Alpha cells': '0.270', 'Beta cells': '0.152', 'Prostate glandular cells': '0.764', 'Prostate basal glandular cells': '0.540', 'Urothelial cells': '0.205', 'Keratinocyte (other)': '0.510', 'Keratinocyte (granular)': '0.055', 'Hair cortex cells': '0.080', 'Inner root sheath cells': '0.131', 'Outer root sheath cells': '0.175', 'Sebaceous gland cells': '0.156', 'Eccrine sweat gland cells': '-0.207', 'Adipocytes (Skin)': '-0.244', 'Mitotic cells (Skin)': '0.442', 'Parietal cells': '0.654', 'Chief cells': '0.649', 'Gastric mucous cells': '0.781', 'Gastric enteroendocrine cells': '0.590', 'Mitotic cells (Stomach)': '0.445', 'Parafollicular cells': '0.173', 'Thyroid glandular cells': '0.865', 'Mitotic cells (Thyroid)': '-0.081', 'Adrenal cortex cells': '0.051', 'Adrenal medulla cells': '0.087', 'Mitotic cells (Adrenal gland)': '0.072', 'Minor salivary glandular cells': '0.371', 'Minor salivary gland ductal cells': '-0.142', 'Minor salivary gland basal cells': '0.582', 'Mitotic cells (Minor salivary gland)': '0.567', 'Adipocytes (Minor salivary gland)': '0.050', 'Somatotropes': '0.121', 'Lactotropes': '0.322', 'Gonadotropes': '0.330', 'Corticotropes': '0.180', 'Thyrotropes': '0.496', 'Undifferentiated cells (Pituitary gland)': '-0.108', 'Mitotic cells (Spleen)': '-0.228', 'Platelets': '-0.050', 'Erythrocytes': '-0.158', 'Hematopoietic stem cells': '-0.211', 'B-cells (Spleen)': '0.266', 'NK-cells (Spleen)': '0.309', 'Amygdala excitatory': '1.0', 'Cerebellar inhibitory': '0.9', 'Cge interneuron': '0.7', 'Deep-layer corticothalamic and 6b': '1.5', 'Deep-layer intratelencephalic': '0.7', 'Deep-layer near-projecting': '0.7', 'Eccentric medium spiny neuron': '0.6', 'Hippocampal ca1-3': '1.9', 'Hippocampal ca4': '1.2', 'Hippocampal dentate gyrus': '1.1', 'Lamp5-lhx6 and chandelier': '0.5', 'Lower rhombic lip': '0.8', 'Mammillary body': '0.6', 'Medium spiny neuron': '0.7', 'Mge interneuron': '1.7', 'Midbrain-derived inhibitory': '0.7', 'Miscellaneous': '0.9', 'Splatter': '3.8', 'Thalamic excitatory': '0.5', 'Upper rhombic lip': '0.8', 'Upper-layer intratelencephalic': '0.6', 'Astrocyte': '4.4', 'Bergmann glia': '0.2', 'Central nervous system macrophage': '0.6', 'Choroid plexus epithelial cell': '52.1', 'Committed oligodendrocyte precursor': '41.5', 'Ependymal cell': '4.8', 'Oligodendrocyte': '53.1', 'Oligodendrocyte precursor cell': '2.4', 'Endothelial cell': '0.7', 'Pericyte': '0.3', 'Vascular associated smooth muscle cell': '0.0', 'Fibroblast': '17.4', 'Leukocyte': '1.1', 'Basophil': '0.0', 'Eosinophil': '0.0', 'Neutrophil': '0.0', 'Classical monocyte': '0.0', 'Non-classical monocyte': '0.0', 'Intermediate monocyte': '0.0', 'T-reg': '2.3', 'GdT-cell': '0.0', 'MAIT T-cell': '0.0', 'Memory CD4 T-cell': '0.0', 'Naive CD4 T-cell': '0.1', 'Memory CD8 T-cell': '0.2', 'Naive CD8 T-cell': '0.3', 'Memory B-cell': '0.0', 'Naive B-cell': '0.1', 'Plasmacytoid DC': '46.6', 'Myeloid DC': '8.5', 'NK-cell': '0.1', 'Total PBMC': '0.7', 'Vd2 gdTCR': '0.0', 'Memory CD4 T-cell Th1\\/Th17': '0.1', 'Memory CD4 T-cell Th17': '0.2', 'Memory CD4 T-cell Th2': '2.9', 'Non-Vd2 gdTCR': '0.1', 'Memory CD4 T-cell Th1': '0.3', 'Memory CD4 T-cell TFH': '0.5', 'Terminal effector memory CD4 T-cell': '0.0', 'Central memory CD8 T-cell': '4.8', 'Effector memory CD8 T-cell': '0.0', 'Terminal effector memory CD8 T-cell': '0.6', 'Non-switched memory B-cell': '0.0', 'Plasmablast': '3.3', 'Switched memory B-cell': '0.0', 'Exhausted memory B-cell': '0.7', 'Progenitor cell': '2.3', 'Memory T-reg': '1.3', 'Naive CD4 T-cell activated': '0.3', 'Naive CD8 T-cell activated': '0.6', 'Naive T-reg': '0.1'}
1O6S, 2O72, 2OMT, 2OMU, 2OMV, 2OMX, 2OMY, 2OMZ, 3FF7, 3FF8, 3L6X, 3L6Y, 4ZT1, 4ZTE, 6CXY, 6OLE, 6OLF, 6OLG, 6VEL, 7STZ, 8H62
{'Adipose Tissue': 1.2125261088039867, 'Adrenal Gland': 0.1914223992248062, 'Bladder': 39.2033519047619, 'Blood': 1.340954264800861, 'Blood Vessel': 0.3121561692883895, 'Brain': 0.8550442199091597, 'Breast': 38.54918344226579, 'Cervix Uteri': 23.539115789473684, 'Colon': 43.41292142490372, 'Esophagus': 53.97513367404844, 'Fallopian Tube': 14.900277777777776, 'Heart': 0.119140469221835, 'Kidney': 25.040449438202245, 'Liver': 26.60802654867257, 'Lung': 35.447986366782004, 'Muscle': 0.1378936151930261, 'Nerve': 17.518468982229404, 'Ovary': 3.6515122222222223, 'Pancreas': 56.89676829268293, 'Pituitary': 24.68741660777385, 'Prostate': 61.279967346938776, 'Salivary Gland': 92.01685185185184, 'Skin': 79.77571720232172, 'Small Intestine': 71.7519320855615, 'Spleen': 10.061029045643156, 'Stomach': 58.07813805013927, 'Testis': 0.8144204986149585, 'Thyroid': 135.176797856049, 'Uterus': 1.442593943661972, 'Vagina': 86.52345512820513}
NUSAP1
MIIPSLEELDSLKYSDLQNLAKSLGLRANLRATKLLKALKGYIKHEARKGNENQDESQTSASSCDETEIQISNQEEAERQPLGHVTKTRRRCKTVRVDPDSQQNHSEIKISNPTEFQNHEKQESQDLRATAKVPSPPDEHQEAENAVSSGNRDSKVPSEGKKSLYTDESSKPGKNKRTAITTPNFKKLHEAHFKEMESIDQYIERKKKHFEEHNSMNELKQQPINKGGVRTPVPPRGRLSVASTPISQRRSQGRSCGPASQSTLGLKGSLKRSAISAAKTGVRFSAATKDNEHKRSLTKTPARKSAHVTVSGGTPKGEAVLGTHKLKTITGNSAAVITPFKLTTEATQTPVSNKKPVFDLKASLSRPLNYEPHKGKLKPWGQSKENNYLNQHVNRINFYKKTYKQPHLQTKEEQRKKREQERKEKKAKVLGMRRGLILAED
Homo sapiens
Cytoplasm, Nucleus, nucleolus, Cytoplasm, cytoskeleton, spindle, Chromosome
Group enriched (bone marrow, lymphoid tissue)
{'Ciliated cells': '0.5', 'Basal respiratory cells': '2.6', 'Club cells': '0.7', 'Ionocytes': '1.1', 'Mucus glandular cells': '0.2', 'Serous glandular cells': '4.4', 'Gastric mucus-secreting cells': '2.9', 'Proximal enterocytes': '0.6', 'Paneth cells': '0.1', 'Distal enterocytes': '0.2', 'Intestinal goblet cells': '2.9', 'Exocrine glandular cells': '-0.348', 'Basal prostatic cells': '1.2', 'Prostatic glandular cells': '0.0', 'Breast glandular cells': '0.280', 'Breast myoepithelial cells': '0.280', 'Glandular and luminal cells': '2.0', 'Secretory cells': '0.4', 'Basal keratinocytes': '6.5', 'Suprabasal keratinocytes': '3.0', 'Basal squamous epithelial cells': '4.4', 'Squamous epithelial cells': '5.5', 'Alveolar cells type 1': '-0.250', 'Alveolar cells type 2': '0.051', 'Salivary duct cells': '0.4', 'Ductal cells': '0.551', 'Hepatocytes': '0.495', 'Cholangiocytes': '1.9', 'Proximal tubular cells': '0.525', 'Distal tubular cells': '0.0', 'Collecting duct cells': '0.0', 'Mesothelial cells': '0.076', 'Sertoli cells': '-0.381', 'Granulosa cells': '1.2', 'Enteroendocrine cells': '1.0', 'Pancreatic endocrine cells': '10.2', 'Leydig cells': '-0.301', 'Excitatory neurons': '1.3', 'Inhibitory neurons': '1.4', 'Cone photoreceptor cells': '0.0', 'Rod photoreceptor cells': '0.0', 'Bipolar cells': '0.0', 'Horizontal cells': '0.0', 'Astrocytes': '1.2', 'Oligodendrocyte precursor cells': '0.9', 'Oligodendrocytes': '1.2', 'Microglial cells': '1.8', 'Muller glia cells': '0.0', 'Schwann cells': '0.022', 'Spermatogonia': '-0.069', 'Spermatocytes': '0.437', 'Early spermatids': '0.763', 'Late spermatids': '0.363', 'Oocytes': '2.2', 'Cytotrophoblasts': '11.3', 'Syncytiotrophoblasts': '3.8', 'Extravillous trophoblasts': '16.7', 'Endothelial cells': '0.6', 'Lymphatic endothelial cells': '0.0', 'Cardiomyocytes': '0.371', 'Skeletal myocytes': '0.429', 'Smooth muscle cells': '0.6', 'Adipocytes': '0.1', 'Melanocytes': '0.542', 'Fibroblasts': '1.9', 'Peritubular cells': '-0.237', 'Endometrial stromal cells': '0.6', 'Ovarian stromal cells': '1.4', 'Undifferentiated cells': '16.9', 'T-cells': '3.1', 'B-cells': '0.7', 'Plasma cells': '7.0', 'Nk-cells': '2.2', 'Granulocytes': '0.1', 'Monocytes': '0.7', 'Macrophages': '2.6', 'Hofbauer cells': '4.3', 'Kupffer cells': '1.4', 'Dendritic cells': '1.2', 'Langerhans cells': '0.238', 'Erythroid cells': '0.046', 'Adipocytes (Subcutaneous)': '-0.114', 'Adipocytes (Visceral)': '-0.172', 'Breast glandular cells (progenitors)': '0.308', 'Adipocytes (Breast)': '-0.244', 'Colon enterocytes': '0.262', 'Colon enteroendocrine cells': '-0.038', 'Enteric glia cells': '-0.185', 'Mitotic cells (Colon)': '0.734', 'Mitotic cells (Heart)': '0.792', 'Podocytes': '0.001', 'Ascending Loop of Henle cells': '0.060', 'Intercalated cells': '-0.105', 'Cholangiocyte': '0.281', 'NK-cells (Liver)': '-0.239', 'Respiratory ciliated cells': '-0.004', 'Mitotic cells (Lung)': '0.875', 'NK-cells (Lung)': '-0.051', 'B-cells (Lung)': '0.090', 'Alpha cells': '0.214', 'Beta cells': '0.089', 'Prostate glandular cells': '-0.270', 'Prostate basal glandular cells': '0.163', 'Urothelial cells': '0.292', 'Keratinocyte (other)': '0.316', 'Keratinocyte (granular)': '-0.213', 'Hair cortex cells': '0.085', 'Inner root sheath cells': '0.242', 'Outer root sheath cells': '0.264', 'Sebaceous gland cells': '0.092', 'Eccrine sweat gland cells': '-0.060', 'Adipocytes (Skin)': '-0.210', 'Mitotic cells (Skin)': '0.911', 'Parietal cells': '0.092', 'Chief cells': '0.037', 'Gastric mucous cells': '0.543', 'Gastric enteroendocrine cells': '0.168', 'Mitotic cells (Stomach)': '0.943', 'Parafollicular cells': '-0.058', 'Thyroid glandular cells': '-0.151', 'Mitotic cells (Thyroid)': '0.784', 'Adrenal cortex cells': '0.511', 'Adrenal medulla cells': '-0.079', 'Mitotic cells (Adrenal gland)': '0.372', 'Minor salivary glandular cells': '0.135', 'Minor salivary gland ductal cells': '-0.306', 'Minor salivary gland basal cells': '0.707', 'Mitotic cells (Minor salivary gland)': '0.960', 'Adipocytes (Minor salivary gland)': '0.178', 'Somatotropes': '-0.278', 'Lactotropes': '-0.266', 'Gonadotropes': '-0.121', 'Corticotropes': '-0.139', 'Thyrotropes': '0.016', 'Undifferentiated cells (Pituitary gland)': '0.401', 'Mitotic cells (Spleen)': '0.955', 'Platelets': '0.146', 'Erythrocytes': '0.343', 'Hematopoietic stem cells': '0.427', 'B-cells (Spleen)': '-0.137', 'NK-cells (Spleen)': '-0.204', 'Amygdala excitatory': '0.1', 'Cerebellar inhibitory': '0.0', 'Cge interneuron': '0.0', 'Deep-layer corticothalamic and 6b': '0.0', 'Deep-layer intratelencephalic': '0.0', 'Deep-layer near-projecting': '0.0', 'Eccentric medium spiny neuron': '0.1', 'Hippocampal ca1-3': '0.1', 'Hippocampal ca4': '0.0', 'Hippocampal dentate gyrus': '0.2', 'Lamp5-lhx6 and chandelier': '0.1', 'Lower rhombic lip': '0.0', 'Mammillary body': '0.0', 'Medium spiny neuron': '0.1', 'Mge interneuron': '0.0', 'Midbrain-derived inhibitory': '0.1', 'Miscellaneous': '0.0', 'Splatter': '0.1', 'Thalamic excitatory': '0.0', 'Upper rhombic lip': '0.0', 'Upper-layer intratelencephalic': '0.0', 'Astrocyte': '0.3', 'Bergmann glia': '0.5', 'Central nervous system macrophage': '0.3', 'Choroid plexus epithelial cell': '0.1', 'Committed oligodendrocyte precursor': '0.0', 'Ependymal cell': '0.2', 'Oligodendrocyte': '0.1', 'Oligodendrocyte precursor cell': '0.1', 'Endothelial cell': '0.3', 'Pericyte': '0.0', 'Vascular associated smooth muscle cell': '0.0', 'Fibroblast': '0.0', 'Leukocyte': '0.0', 'Basophil': '2.2', 'Eosinophil': '0.5', 'Neutrophil': '0.2', 'Classical monocyte': '4.8', 'Non-classical monocyte': '4.5', 'Intermediate monocyte': '1.7', 'T-reg': '7.8', 'GdT-cell': '0.1', 'MAIT T-cell': '0.4', 'Memory CD4 T-cell': '0.6', 'Naive CD4 T-cell': '2.1', 'Memory CD8 T-cell': '0.5', 'Naive CD8 T-cell': '1.8', 'Memory B-cell': '0.3', 'Naive B-cell': '7.3', 'Plasmacytoid DC': '2.9', 'Myeloid DC': '1.1', 'NK-cell': '6.1', 'Total PBMC': '4.8', 'Vd2 gdTCR': '0.6', 'Memory CD4 T-cell Th1\\/Th17': '2.9', 'Memory CD4 T-cell Th17': '8.3', 'Memory CD4 T-cell Th2': '9.8', 'Non-Vd2 gdTCR': '1.0', 'Memory CD4 T-cell Th1': '6.3', 'Memory CD4 T-cell TFH': '5.6', 'Terminal effector memory CD4 T-cell': '0.1', 'Central memory CD8 T-cell': '1.7', 'Effector memory CD8 T-cell': '8.4', 'Terminal effector memory CD8 T-cell': '1.2', 'Non-switched memory B-cell': '0.5', 'Plasmablast': '66.2', 'Switched memory B-cell': '4.5', 'Exhausted memory B-cell': '4.4', 'Progenitor cell': '4.1', 'Memory T-reg': '26.4', 'Naive CD4 T-cell activated': '2.0', 'Naive CD8 T-cell activated': '1.4', 'Naive T-reg': '3.6'}
null
{'Adipose Tissue': 3.0626249169435216, 'Adrenal Gland': 20.066418604651165, 'Bladder': 2.5714285714285716, 'Blood': 38.67838557588806, 'Blood Vessel': 1.907438127340824, 'Brain': 0.921281385314156, 'Breast': 2.6828954248366013, 'Cervix Uteri': 4.126584210526316, 'Colon': 5.369006418485237, 'Esophagus': 10.88004830449827, 'Fallopian Tube': 2.6983444444444444, 'Heart': 0.9591686178861788, 'Kidney': 2.958684269662921, 'Liver': 3.8981778761061943, 'Lung': 8.120652249134949, 'Muscle': 4.355879825653798, 'Nerve': 2.3376048465266557, 'Ovary': 9.89653888888889, 'Pancreas': 1.0126895426829268, 'Pituitary': 1.4382194346289752, 'Prostate': 2.505309795918367, 'Salivary Gland': 5.667204320987654, 'Skin': 27.983096738529575, 'Small Intestine': 12.297466310160427, 'Spleen': 13.0189377593361, 'Stomach': 6.007349025069638, 'Testis': 25.17539335180055, 'Thyroid': 2.2111070444104137, 'Uterus': 2.285015492957746, 'Vagina': 12.095448076923075}
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[0.79, 0.91, 0.53, 0.18, 0.44, 0.4, 0.8, 0.49, 0.0, 0.56, 0.81, 0.32, 0.73, 0.4, 0.53, 0.41, 0.02, 0.26, 0.54, 0.1, 0.0, 0.62, 0.42, 0.22, 0.81, 0.29, 0.66, 0.13, 0.73, 0.27, 0.81, 0.37, 0.74, 0.64, 0.0, 0.22, 0.78, 0.39, 0.01, 0.27, 0.44, 0.28, 0.19, 0.59, 0.56, 0.47, 0.57, 0.78, 0.55, 0.66, 0.82, 0.87, 0.74, 0.98, 0.96, 0.98, 1.0, 0.96, 1.0, 1.0, 1.0, 1.0, 0.99, 1.0, 0.93, 1.0, 0.76, 0.91, 0.74, 0.87, 0.83, 0.84, 0.9, 0.95, 1.0, 0.99, 1.0, 1.0, 0.93, 0.99, 0.84, 0.99, 0.97, 1.0, 0.95, 1.0, 0.95, 0.98, 0.91, 0.94, 0.99, 0.75, 0.92, 0.82, 0.76, 0.87, 0.84, 0.91, 0.92, 0.98, 0.99, 1.0, 0.98, 0.99, 0.98, 0.97, 0.95, 0.98, 0.94, 0.87, 0.98, 0.86, 0.99, 0.86, 0.92, 0.94, 0.78, 1.0, 0.81, 1.0, 0.99, 0.97, 0.96, 0.94, 0.95, 1.0, 1.0, 1.0, 1.0, 0.99, 0.99, 0.98, 0.99, 0.98, 0.99, 0.99, 0.99, 1.0, 1.0, 1.0, 1.0, 0.98, 1.0, 0.98, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 0.99, 1.0, 0.98, 0.99, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 0.98, 1.0, 0.97, 0.94, 0.89, 0.75, 0.83, 0.8, 0.96, 0.9, 0.95, 0.96, 0.82, 0.89, 0.93, 0.88, 0.95, 0.84, 0.75, 0.97, 0.74, 0.87, 0.55, 0.6, 0.54, 0.78, 0.72, 0.57, 0.53, 0.5, 0.54, 0.55, 0.7, 0.7, 0.77, 0.62, 0.31, 0.56, 0.68, 0.65, 0.55, 0.46, 0.58, 0.64, 0.6, 0.53, 0.71, 0.63, 0.51, 0.65, 0.71, 0.64, 0.54, 0.37, 0.53, 0.74, 0.56, 0.76, 0.74, 0.86, 0.85, 0.83, 0.79, 0.94, 0.86, 0.97, 0.96, 1.0, 0.97, 0.98, 0.95, 0.93, 0.96, 0.92, 0.97, 0.97, 0.87, 0.98, 0.93, 0.98, 0.88, 0.98, 0.89, 1.0, 0.99, 0.95, 1.0, 0.94, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 0.97, 0.99, 0.98, 0.96, 0.98, 0.91, 0.99, 0.96, 1.0, 1.0, 1.0, 0.98, 1.0, 0.95, 1.0, 0.93, 0.93, 0.78, 0.94, 0.8, 0.88, 0.77, 0.93, 0.82, 0.8, 0.61, 0.88, 0.86, 0.65, 0.96, 0.88, 0.68, 1.0, 0.81, 0.57, 0.77, 0.85, 0.76, 0.86, 0.88, 0.74, 0.85, 0.78, 0.83, 0.86, 0.84, 0.95, 0.95, 0.76, 0.88, 0.83, 0.8, 0.8, 0.84, 0.81, 0.97, 0.85, 0.98, 0.92, 0.98, 0.93, 0.94, 0.97, 0.9, 0.98, 0.86, 0.94, 0.86, 0.97, 0.83, 0.97, 0.86, 0.93, 0.9, 0.95, 1.0, 0.95, 0.99, 0.82, 0.82, 0.93, 0.49, 0.96, 0.95, 0.7, 0.9, 0.71, 0.86, 0.74, 0.85, 0.76, 0.91, 0.78, 0.81, 0.88, 0.59, 0.95, 0.82, 0.9, 0.94, 0.83, 0.74, 0.49, 0.54, 0.77, 0.45, 0.38, 0.7, 0.71, 0.76, 0.84, 0.62, 0.93, 0.69, 0.97, 0.58, 0.61, 0.91, 0.63, 0.95, 0.77, 0.95, 0.88, 0.93, 0.73, 0.94, 0.73, 0.86, 0.63, 0.6, 0.69, 0.65, 0.45, 0.63, 0.67, 0.47, 0.51, 0.53, 0.58, 0.38, 0.45, 0.63, 0.62, 0.7, 0.85, 0.42, 0.84, 0.98, 0.82, 0.79, 0.76, 0.82, 0.47, 0.6, 0.67, 0.56, 0.42, 0.48, 0.63, 0.59, 0.66, 0.62, 0.52, 0.61, 0.45, 0.69, 0.56, 0.68, 0.57, 0.67, 0.55, 0.7, 0.5, 0.42, 0.15, 0.65, 0.81, 0.73, 0.64, 0.63, 0.79, 0.83, 0.76, 0.86, 0.94]
null
Component of an E-cadherin/ catenin adhesion complex composed of at least E-cadherin/CDH1, beta-catenin/CTNNB1 or gamma-catenin/JUP, and potentially alpha-catenin/CTNNA1. Forms a ternary complex composed of ADAM10, CADH1 and EPHA4,
null
null
KLRG1, SPEF1, DLGAP5, AJAP1, RAPGEF2, RAB8B, PIP5K1C, PKP2, TRPV4, CTNNB1, CAV1, DDR1, TBC1D2, CTNNA1, JUP, CTNND1, PSEN1, LIMA1, CDH1, JUP, ADAM10, CADH1 , EPHA4,
null
null
null
null
Homodimer
null
79.91949
0.474025
62.090499
0.79
1,804
P12830
Q9BXS6-2
null
degron_data
CDH1
MGPWSRSLSALLLLLQVSSWLCQEPEPCHPGFDAESYTFTVPRRHLERGRVLGRVNFEDCTGRQRTAYFSLDTRFKVGTDGVITVKRPLRFHNPQIHFLVYAWDSTYRKFSTKVTLNTVGHHHRPPPHQASVSGIQAELLTFPNSSPGLRRQKRDWVIPPISCPENEKGPFPKNLVQIKSNKDKEGKVFYSITGQGADTPPVGVFIIERETGWLKVTEPLDRERIATYTLFSHAVSSNGNAVEDPMEILITVTDQNDNKPEFTQEVFKGSVMEGALPGTSVMEVTATDADDDVNTYNAAIAYTILSQDPELPDKNMFTINRNTGVISVVTTGLDRESFPTYTLVVQAADLQGEGLSTTATAVITVTDTNDNPPIFNPTTYKGQVPENEANVVITTLKVTDADAPNTPAWEAVYTILNDDGGQFVVTTNPVNNDGILKTAKGLDFEAKQQYILHVAVTNVVPFEVSLTTSTATVTVDVLDVNEAPIFVPPEKRVEVSEDFGVGQEITSYTAQEPDTFMEQKITYRIWRDTANWLEINPDTGAISTRAELDREDFEHVKNSTYTALIIATDNGSPVATGTGTLLLILSDVNDNAPIPEPRTIFFCERNPKPQVINIIDADLPPNTSPFTAELTHGASANWTIQYNDPTQESIILKPKMALEVGDYKINLKLMDNQNKDQVTTLEVSVCDCEGAAGVCRKAQPVEAGLQIPAILGILGGILALLILILLLLLFLRRRAVVKEPLLPPEDDTRDNVYYYDEEGGGEEDQDFDLSQLHRGLDARPEVTRNDVAPTLMSVPRYLPRPANPDEIGNFIDENLKAADTDPTAPPYDSLLVFDYEGSGSEAASLSSLNSSESDKDQDYDYLNEWGNRFKKLADMYGGGEDD
Homo sapiens
Cell junction, adherens junction, Cell membrane, Endosome, Golgi apparatus, trans-Golgi network, Cytoplasm, Cell junction, desmosome
Tissue enhanced (parathyroid)
{'Ciliated cells': '119.1', 'Basal respiratory cells': '71.1', 'Club cells': '97.3', 'Ionocytes': '81.0', 'Mucus glandular cells': '155.0', 'Serous glandular cells': '67.8', 'Gastric mucus-secreting cells': '133.2', 'Proximal enterocytes': '140.9', 'Paneth cells': '125.1', 'Distal enterocytes': '307.5', 'Intestinal goblet cells': '173.5', 'Exocrine glandular cells': '-0.605', 'Basal prostatic cells': '68.3', 'Prostatic glandular cells': '186.7', 'Breast glandular cells': '0.773', 'Breast myoepithelial cells': '0.700', 'Glandular and luminal cells': '313.0', 'Secretory cells': '82.3', 'Basal keratinocytes': '102.5', 'Suprabasal keratinocytes': '162.6', 'Basal squamous epithelial cells': '51.0', 'Squamous epithelial cells': '106.9', 'Alveolar cells type 1': '0.437', 'Alveolar cells type 2': '0.706', 'Salivary duct cells': '95.9', 'Ductal cells': '0.541', 'Hepatocytes': '0.600', 'Cholangiocytes': '129.7', 'Proximal tubular cells': '0.042', 'Distal tubular cells': '0.0', 'Collecting duct cells': '143.9', 'Mesothelial cells': '0.799', 'Sertoli cells': '0.252', 'Granulosa cells': '12.9', 'Enteroendocrine cells': '92.4', 'Pancreatic endocrine cells': '78.1', 'Leydig cells': '0.264', 'Excitatory neurons': '0.7', 'Inhibitory neurons': '1.3', 'Cone photoreceptor cells': '0.0', 'Rod photoreceptor cells': '0.0', 'Bipolar cells': '0.2', 'Horizontal cells': '0.6', 'Astrocytes': '0.6', 'Oligodendrocyte precursor cells': '0.5', 'Oligodendrocytes': '29.9', 'Microglial cells': '0.9', 'Muller glia cells': '0.1', 'Schwann cells': '0.131', 'Spermatogonia': '0.392', 'Spermatocytes': '0.193', 'Early spermatids': '-0.217', 'Late spermatids': '-0.290', 'Oocytes': '16.9', 'Cytotrophoblasts': '119.2', 'Syncytiotrophoblasts': '45.0', 'Extravillous trophoblasts': '24.9', 'Endothelial cells': '6.1', 'Lymphatic endothelial cells': '0.4', 'Cardiomyocytes': '0.135', 'Skeletal myocytes': '0.107', 'Smooth muscle cells': '5.8', 'Adipocytes': '2.1', 'Melanocytes': '0.335', 'Fibroblasts': '6.5', 'Peritubular cells': '0.210', 'Endometrial stromal cells': '27.7', 'Ovarian stromal cells': '0.7', 'Undifferentiated cells': '101.6', 'T-cells': '2.9', 'B-cells': '4.4', 'Plasma cells': '6.1', 'Nk-cells': '0.0', 'Granulocytes': '8.4', 'Monocytes': '0.0', 'Macrophages': '6.0', 'Hofbauer cells': '4.3', 'Kupffer cells': '1.0', 'Dendritic cells': '5.9', 'Langerhans cells': '0.304', 'Erythroid cells': '0.036', 'Adipocytes (Subcutaneous)': '-0.081', 'Adipocytes (Visceral)': '-0.209', 'Breast glandular cells (progenitors)': '0.538', 'Adipocytes (Breast)': '-0.689', 'Colon enterocytes': '0.790', 'Colon enteroendocrine cells': '0.112', 'Enteric glia cells': '-0.048', 'Mitotic cells (Colon)': '0.299', 'Mitotic cells (Heart)': '0.120', 'Podocytes': '-0.118', 'Ascending Loop of Henle cells': '0.475', 'Intercalated cells': '0.212', 'Cholangiocyte': '0.090', 'NK-cells (Liver)': '-0.005', 'Respiratory ciliated cells': '-0.012', 'Mitotic cells (Lung)': '0.071', 'NK-cells (Lung)': '-0.266', 'B-cells (Lung)': '-0.296', 'Alpha cells': '0.270', 'Beta cells': '0.152', 'Prostate glandular cells': '0.764', 'Prostate basal glandular cells': '0.540', 'Urothelial cells': '0.205', 'Keratinocyte (other)': '0.510', 'Keratinocyte (granular)': '0.055', 'Hair cortex cells': '0.080', 'Inner root sheath cells': '0.131', 'Outer root sheath cells': '0.175', 'Sebaceous gland cells': '0.156', 'Eccrine sweat gland cells': '-0.207', 'Adipocytes (Skin)': '-0.244', 'Mitotic cells (Skin)': '0.442', 'Parietal cells': '0.654', 'Chief cells': '0.649', 'Gastric mucous cells': '0.781', 'Gastric enteroendocrine cells': '0.590', 'Mitotic cells (Stomach)': '0.445', 'Parafollicular cells': '0.173', 'Thyroid glandular cells': '0.865', 'Mitotic cells (Thyroid)': '-0.081', 'Adrenal cortex cells': '0.051', 'Adrenal medulla cells': '0.087', 'Mitotic cells (Adrenal gland)': '0.072', 'Minor salivary glandular cells': '0.371', 'Minor salivary gland ductal cells': '-0.142', 'Minor salivary gland basal cells': '0.582', 'Mitotic cells (Minor salivary gland)': '0.567', 'Adipocytes (Minor salivary gland)': '0.050', 'Somatotropes': '0.121', 'Lactotropes': '0.322', 'Gonadotropes': '0.330', 'Corticotropes': '0.180', 'Thyrotropes': '0.496', 'Undifferentiated cells (Pituitary gland)': '-0.108', 'Mitotic cells (Spleen)': '-0.228', 'Platelets': '-0.050', 'Erythrocytes': '-0.158', 'Hematopoietic stem cells': '-0.211', 'B-cells (Spleen)': '0.266', 'NK-cells (Spleen)': '0.309', 'Amygdala excitatory': '1.0', 'Cerebellar inhibitory': '0.9', 'Cge interneuron': '0.7', 'Deep-layer corticothalamic and 6b': '1.5', 'Deep-layer intratelencephalic': '0.7', 'Deep-layer near-projecting': '0.7', 'Eccentric medium spiny neuron': '0.6', 'Hippocampal ca1-3': '1.9', 'Hippocampal ca4': '1.2', 'Hippocampal dentate gyrus': '1.1', 'Lamp5-lhx6 and chandelier': '0.5', 'Lower rhombic lip': '0.8', 'Mammillary body': '0.6', 'Medium spiny neuron': '0.7', 'Mge interneuron': '1.7', 'Midbrain-derived inhibitory': '0.7', 'Miscellaneous': '0.9', 'Splatter': '3.8', 'Thalamic excitatory': '0.5', 'Upper rhombic lip': '0.8', 'Upper-layer intratelencephalic': '0.6', 'Astrocyte': '4.4', 'Bergmann glia': '0.2', 'Central nervous system macrophage': '0.6', 'Choroid plexus epithelial cell': '52.1', 'Committed oligodendrocyte precursor': '41.5', 'Ependymal cell': '4.8', 'Oligodendrocyte': '53.1', 'Oligodendrocyte precursor cell': '2.4', 'Endothelial cell': '0.7', 'Pericyte': '0.3', 'Vascular associated smooth muscle cell': '0.0', 'Fibroblast': '17.4', 'Leukocyte': '1.1', 'Basophil': '0.0', 'Eosinophil': '0.0', 'Neutrophil': '0.0', 'Classical monocyte': '0.0', 'Non-classical monocyte': '0.0', 'Intermediate monocyte': '0.0', 'T-reg': '2.3', 'GdT-cell': '0.0', 'MAIT T-cell': '0.0', 'Memory CD4 T-cell': '0.0', 'Naive CD4 T-cell': '0.1', 'Memory CD8 T-cell': '0.2', 'Naive CD8 T-cell': '0.3', 'Memory B-cell': '0.0', 'Naive B-cell': '0.1', 'Plasmacytoid DC': '46.6', 'Myeloid DC': '8.5', 'NK-cell': '0.1', 'Total PBMC': '0.7', 'Vd2 gdTCR': '0.0', 'Memory CD4 T-cell Th1\\/Th17': '0.1', 'Memory CD4 T-cell Th17': '0.2', 'Memory CD4 T-cell Th2': '2.9', 'Non-Vd2 gdTCR': '0.1', 'Memory CD4 T-cell Th1': '0.3', 'Memory CD4 T-cell TFH': '0.5', 'Terminal effector memory CD4 T-cell': '0.0', 'Central memory CD8 T-cell': '4.8', 'Effector memory CD8 T-cell': '0.0', 'Terminal effector memory CD8 T-cell': '0.6', 'Non-switched memory B-cell': '0.0', 'Plasmablast': '3.3', 'Switched memory B-cell': '0.0', 'Exhausted memory B-cell': '0.7', 'Progenitor cell': '2.3', 'Memory T-reg': '1.3', 'Naive CD4 T-cell activated': '0.3', 'Naive CD8 T-cell activated': '0.6', 'Naive T-reg': '0.1'}
1O6S, 2O72, 2OMT, 2OMU, 2OMV, 2OMX, 2OMY, 2OMZ, 3FF7, 3FF8, 3L6X, 3L6Y, 4ZT1, 4ZTE, 6CXY, 6OLE, 6OLF, 6OLG, 6VEL, 7STZ, 8H62
{'Adipose Tissue': 1.2125261088039867, 'Adrenal Gland': 0.1914223992248062, 'Bladder': 39.2033519047619, 'Blood': 1.340954264800861, 'Blood Vessel': 0.3121561692883895, 'Brain': 0.8550442199091597, 'Breast': 38.54918344226579, 'Cervix Uteri': 23.539115789473684, 'Colon': 43.41292142490372, 'Esophagus': 53.97513367404844, 'Fallopian Tube': 14.900277777777776, 'Heart': 0.119140469221835, 'Kidney': 25.040449438202245, 'Liver': 26.60802654867257, 'Lung': 35.447986366782004, 'Muscle': 0.1378936151930261, 'Nerve': 17.518468982229404, 'Ovary': 3.6515122222222223, 'Pancreas': 56.89676829268293, 'Pituitary': 24.68741660777385, 'Prostate': 61.279967346938776, 'Salivary Gland': 92.01685185185184, 'Skin': 79.77571720232172, 'Small Intestine': 71.7519320855615, 'Spleen': 10.061029045643156, 'Stomach': 58.07813805013927, 'Testis': 0.8144204986149585, 'Thyroid': 135.176797856049, 'Uterus': 1.442593943661972, 'Vagina': 86.52345512820513}
NUSAP1
MIIPSLEELDSLKYSDLQNLAKSLGLRANLRATKLLKALKGYIKHEARKGNENQDESQTSASSCDETEIQISNQEEAERQPLGHVTKTRRRCKTVRVDPDSQQNHSEIKISNPTEFQNHEKQESQDLRATAKVPSPPDEHQEAENAVSSGNRDSKVPSEGKKSLYTDESSKPGKNKRTAITTPNFKKLHEAHFKEMESIDQYIERKKKHFEEHNSMNELKQPINKGGVRTPVPPRGRLSVASTPISQRRSQGRSCGPASQSTLGLKGSLKRSAISAAKTGVRFSAATKDNEHKRSLTKTPARKSAHVTVSGGTPKGEAVLGTHKLKTITGNSAAVITPFKLTTEATQTPVSNKKPVFDLKASLSRPLNYEPHKGKLKPWGQSKENNYLNQHVNRINFYKKTYKQPHLQTKEEQRKKREQERKEKKAKVLGMRRGLILAED
Homo sapiens
null
Not found
{}
null
{'Adipose Tissue': 3.0626249169435216, 'Adrenal Gland': 20.066418604651165, 'Bladder': 2.5714285714285716, 'Blood': 38.67838557588806, 'Blood Vessel': 1.907438127340824, 'Brain': 0.921281385314156, 'Breast': 2.6828954248366013, 'Cervix Uteri': 4.126584210526316, 'Colon': 5.369006418485237, 'Esophagus': 10.88004830449827, 'Fallopian Tube': 2.6983444444444444, 'Heart': 0.9591686178861788, 'Kidney': 2.958684269662921, 'Liver': 3.8981778761061943, 'Lung': 8.120652249134949, 'Muscle': 4.355879825653798, 'Nerve': 2.3376048465266557, 'Ovary': 9.89653888888889, 'Pancreas': 1.0126895426829268, 'Pituitary': 1.4382194346289752, 'Prostate': 2.505309795918367, 'Salivary Gland': 5.667204320987654, 'Skin': 27.983096738529575, 'Small Intestine': 12.297466310160427, 'Spleen': 13.0189377593361, 'Stomach': 6.007349025069638, 'Testis': 25.17539335180055, 'Thyroid': 2.2111070444104137, 'Uterus': 2.285015492957746, 'Vagina': 12.095448076923075}
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73.27, 70.36, 72.63, 72.69, 68.11, 66.06, 60.67, 52.64, 44.07, 48.46, 43.79, 36.31]
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null
null
null
Component of an E-cadherin/ catenin adhesion complex composed of at least E-cadherin/CDH1, beta-catenin/CTNNB1 or gamma-catenin/JUP, and potentially alpha-catenin/CTNNA1. Forms a ternary complex composed of ADAM10, CADH1 and EPHA4,
null
null
KLRG1, SPEF1, DLGAP5, AJAP1, RAPGEF2, RAB8B, PIP5K1C, PKP2, TRPV4, CTNNB1, CAV1, DDR1, TBC1D2, CTNNA1, JUP, CTNND1, PSEN1, LIMA1, CDH1, JUP, ADAM10, CADH1 , EPHA4,
null
null
null
null
Homodimer
null
79.91949
0.474025
null
null
1,804
P12830
Q9BXS6-5
null
degron_data
CDH1
MGPWSRSLSALLLLLQVSSWLCQEPEPCHPGFDAESYTFTVPRRHLERGRVLGRVNFEDCTGRQRTAYFSLDTRFKVGTDGVITVKRPLRFHNPQIHFLVYAWDSTYRKFSTKVTLNTVGHHHRPPPHQASVSGIQAELLTFPNSSPGLRRQKRDWVIPPISCPENEKGPFPKNLVQIKSNKDKEGKVFYSITGQGADTPPVGVFIIERETGWLKVTEPLDRERIATYTLFSHAVSSNGNAVEDPMEILITVTDQNDNKPEFTQEVFKGSVMEGALPGTSVMEVTATDADDDVNTYNAAIAYTILSQDPELPDKNMFTINRNTGVISVVTTGLDRESFPTYTLVVQAADLQGEGLSTTATAVITVTDTNDNPPIFNPTTYKGQVPENEANVVITTLKVTDADAPNTPAWEAVYTILNDDGGQFVVTTNPVNNDGILKTAKGLDFEAKQQYILHVAVTNVVPFEVSLTTSTATVTVDVLDVNEAPIFVPPEKRVEVSEDFGVGQEITSYTAQEPDTFMEQKITYRIWRDTANWLEINPDTGAISTRAELDREDFEHVKNSTYTALIIATDNGSPVATGTGTLLLILSDVNDNAPIPEPRTIFFCERNPKPQVINIIDADLPPNTSPFTAELTHGASANWTIQYNDPTQESIILKPKMALEVGDYKINLKLMDNQNKDQVTTLEVSVCDCEGAAGVCRKAQPVEAGLQIPAILGILGGILALLILILLLLLFLRRRAVVKEPLLPPEDDTRDNVYYYDEEGGGEEDQDFDLSQLHRGLDARPEVTRNDVAPTLMSVPRYLPRPANPDEIGNFIDENLKAADTDPTAPPYDSLLVFDYEGSGSEAASLSSLNSSESDKDQDYDYLNEWGNRFKKLADMYGGGEDD
Homo sapiens
Cell junction, adherens junction, Cell membrane, Endosome, Golgi apparatus, trans-Golgi network, Cytoplasm, Cell junction, desmosome
Tissue enhanced (parathyroid)
{'Ciliated cells': '119.1', 'Basal respiratory cells': '71.1', 'Club cells': '97.3', 'Ionocytes': '81.0', 'Mucus glandular cells': '155.0', 'Serous glandular cells': '67.8', 'Gastric mucus-secreting cells': '133.2', 'Proximal enterocytes': '140.9', 'Paneth cells': '125.1', 'Distal enterocytes': '307.5', 'Intestinal goblet cells': '173.5', 'Exocrine glandular cells': '-0.605', 'Basal prostatic cells': '68.3', 'Prostatic glandular cells': '186.7', 'Breast glandular cells': '0.773', 'Breast myoepithelial cells': '0.700', 'Glandular and luminal cells': '313.0', 'Secretory cells': '82.3', 'Basal keratinocytes': '102.5', 'Suprabasal keratinocytes': '162.6', 'Basal squamous epithelial cells': '51.0', 'Squamous epithelial cells': '106.9', 'Alveolar cells type 1': '0.437', 'Alveolar cells type 2': '0.706', 'Salivary duct cells': '95.9', 'Ductal cells': '0.541', 'Hepatocytes': '0.600', 'Cholangiocytes': '129.7', 'Proximal tubular cells': '0.042', 'Distal tubular cells': '0.0', 'Collecting duct cells': '143.9', 'Mesothelial cells': '0.799', 'Sertoli cells': '0.252', 'Granulosa cells': '12.9', 'Enteroendocrine cells': '92.4', 'Pancreatic endocrine cells': '78.1', 'Leydig cells': '0.264', 'Excitatory neurons': '0.7', 'Inhibitory neurons': '1.3', 'Cone photoreceptor cells': '0.0', 'Rod photoreceptor cells': '0.0', 'Bipolar cells': '0.2', 'Horizontal cells': '0.6', 'Astrocytes': '0.6', 'Oligodendrocyte precursor cells': '0.5', 'Oligodendrocytes': '29.9', 'Microglial cells': '0.9', 'Muller glia cells': '0.1', 'Schwann cells': '0.131', 'Spermatogonia': '0.392', 'Spermatocytes': '0.193', 'Early spermatids': '-0.217', 'Late spermatids': '-0.290', 'Oocytes': '16.9', 'Cytotrophoblasts': '119.2', 'Syncytiotrophoblasts': '45.0', 'Extravillous trophoblasts': '24.9', 'Endothelial cells': '6.1', 'Lymphatic endothelial cells': '0.4', 'Cardiomyocytes': '0.135', 'Skeletal myocytes': '0.107', 'Smooth muscle cells': '5.8', 'Adipocytes': '2.1', 'Melanocytes': '0.335', 'Fibroblasts': '6.5', 'Peritubular cells': '0.210', 'Endometrial stromal cells': '27.7', 'Ovarian stromal cells': '0.7', 'Undifferentiated cells': '101.6', 'T-cells': '2.9', 'B-cells': '4.4', 'Plasma cells': '6.1', 'Nk-cells': '0.0', 'Granulocytes': '8.4', 'Monocytes': '0.0', 'Macrophages': '6.0', 'Hofbauer cells': '4.3', 'Kupffer cells': '1.0', 'Dendritic cells': '5.9', 'Langerhans cells': '0.304', 'Erythroid cells': '0.036', 'Adipocytes (Subcutaneous)': '-0.081', 'Adipocytes (Visceral)': '-0.209', 'Breast glandular cells (progenitors)': '0.538', 'Adipocytes (Breast)': '-0.689', 'Colon enterocytes': '0.790', 'Colon enteroendocrine cells': '0.112', 'Enteric glia cells': '-0.048', 'Mitotic cells (Colon)': '0.299', 'Mitotic cells (Heart)': '0.120', 'Podocytes': '-0.118', 'Ascending Loop of Henle cells': '0.475', 'Intercalated cells': '0.212', 'Cholangiocyte': '0.090', 'NK-cells (Liver)': '-0.005', 'Respiratory ciliated cells': '-0.012', 'Mitotic cells (Lung)': '0.071', 'NK-cells (Lung)': '-0.266', 'B-cells (Lung)': '-0.296', 'Alpha cells': '0.270', 'Beta cells': '0.152', 'Prostate glandular cells': '0.764', 'Prostate basal glandular cells': '0.540', 'Urothelial cells': '0.205', 'Keratinocyte (other)': '0.510', 'Keratinocyte (granular)': '0.055', 'Hair cortex cells': '0.080', 'Inner root sheath cells': '0.131', 'Outer root sheath cells': '0.175', 'Sebaceous gland cells': '0.156', 'Eccrine sweat gland cells': '-0.207', 'Adipocytes (Skin)': '-0.244', 'Mitotic cells (Skin)': '0.442', 'Parietal cells': '0.654', 'Chief cells': '0.649', 'Gastric mucous cells': '0.781', 'Gastric enteroendocrine cells': '0.590', 'Mitotic cells (Stomach)': '0.445', 'Parafollicular cells': '0.173', 'Thyroid glandular cells': '0.865', 'Mitotic cells (Thyroid)': '-0.081', 'Adrenal cortex cells': '0.051', 'Adrenal medulla cells': '0.087', 'Mitotic cells (Adrenal gland)': '0.072', 'Minor salivary glandular cells': '0.371', 'Minor salivary gland ductal cells': '-0.142', 'Minor salivary gland basal cells': '0.582', 'Mitotic cells (Minor salivary gland)': '0.567', 'Adipocytes (Minor salivary gland)': '0.050', 'Somatotropes': '0.121', 'Lactotropes': '0.322', 'Gonadotropes': '0.330', 'Corticotropes': '0.180', 'Thyrotropes': '0.496', 'Undifferentiated cells (Pituitary gland)': '-0.108', 'Mitotic cells (Spleen)': '-0.228', 'Platelets': '-0.050', 'Erythrocytes': '-0.158', 'Hematopoietic stem cells': '-0.211', 'B-cells (Spleen)': '0.266', 'NK-cells (Spleen)': '0.309', 'Amygdala excitatory': '1.0', 'Cerebellar inhibitory': '0.9', 'Cge interneuron': '0.7', 'Deep-layer corticothalamic and 6b': '1.5', 'Deep-layer intratelencephalic': '0.7', 'Deep-layer near-projecting': '0.7', 'Eccentric medium spiny neuron': '0.6', 'Hippocampal ca1-3': '1.9', 'Hippocampal ca4': '1.2', 'Hippocampal dentate gyrus': '1.1', 'Lamp5-lhx6 and chandelier': '0.5', 'Lower rhombic lip': '0.8', 'Mammillary body': '0.6', 'Medium spiny neuron': '0.7', 'Mge interneuron': '1.7', 'Midbrain-derived inhibitory': '0.7', 'Miscellaneous': '0.9', 'Splatter': '3.8', 'Thalamic excitatory': '0.5', 'Upper rhombic lip': '0.8', 'Upper-layer intratelencephalic': '0.6', 'Astrocyte': '4.4', 'Bergmann glia': '0.2', 'Central nervous system macrophage': '0.6', 'Choroid plexus epithelial cell': '52.1', 'Committed oligodendrocyte precursor': '41.5', 'Ependymal cell': '4.8', 'Oligodendrocyte': '53.1', 'Oligodendrocyte precursor cell': '2.4', 'Endothelial cell': '0.7', 'Pericyte': '0.3', 'Vascular associated smooth muscle cell': '0.0', 'Fibroblast': '17.4', 'Leukocyte': '1.1', 'Basophil': '0.0', 'Eosinophil': '0.0', 'Neutrophil': '0.0', 'Classical monocyte': '0.0', 'Non-classical monocyte': '0.0', 'Intermediate monocyte': '0.0', 'T-reg': '2.3', 'GdT-cell': '0.0', 'MAIT T-cell': '0.0', 'Memory CD4 T-cell': '0.0', 'Naive CD4 T-cell': '0.1', 'Memory CD8 T-cell': '0.2', 'Naive CD8 T-cell': '0.3', 'Memory B-cell': '0.0', 'Naive B-cell': '0.1', 'Plasmacytoid DC': '46.6', 'Myeloid DC': '8.5', 'NK-cell': '0.1', 'Total PBMC': '0.7', 'Vd2 gdTCR': '0.0', 'Memory CD4 T-cell Th1\\/Th17': '0.1', 'Memory CD4 T-cell Th17': '0.2', 'Memory CD4 T-cell Th2': '2.9', 'Non-Vd2 gdTCR': '0.1', 'Memory CD4 T-cell Th1': '0.3', 'Memory CD4 T-cell TFH': '0.5', 'Terminal effector memory CD4 T-cell': '0.0', 'Central memory CD8 T-cell': '4.8', 'Effector memory CD8 T-cell': '0.0', 'Terminal effector memory CD8 T-cell': '0.6', 'Non-switched memory B-cell': '0.0', 'Plasmablast': '3.3', 'Switched memory B-cell': '0.0', 'Exhausted memory B-cell': '0.7', 'Progenitor cell': '2.3', 'Memory T-reg': '1.3', 'Naive CD4 T-cell activated': '0.3', 'Naive CD8 T-cell activated': '0.6', 'Naive T-reg': '0.1'}
1O6S, 2O72, 2OMT, 2OMU, 2OMV, 2OMX, 2OMY, 2OMZ, 3FF7, 3FF8, 3L6X, 3L6Y, 4ZT1, 4ZTE, 6CXY, 6OLE, 6OLF, 6OLG, 6VEL, 7STZ, 8H62
{'Adipose Tissue': 1.2125261088039867, 'Adrenal Gland': 0.1914223992248062, 'Bladder': 39.2033519047619, 'Blood': 1.340954264800861, 'Blood Vessel': 0.3121561692883895, 'Brain': 0.8550442199091597, 'Breast': 38.54918344226579, 'Cervix Uteri': 23.539115789473684, 'Colon': 43.41292142490372, 'Esophagus': 53.97513367404844, 'Fallopian Tube': 14.900277777777776, 'Heart': 0.119140469221835, 'Kidney': 25.040449438202245, 'Liver': 26.60802654867257, 'Lung': 35.447986366782004, 'Muscle': 0.1378936151930261, 'Nerve': 17.518468982229404, 'Ovary': 3.6515122222222223, 'Pancreas': 56.89676829268293, 'Pituitary': 24.68741660777385, 'Prostate': 61.279967346938776, 'Salivary Gland': 92.01685185185184, 'Skin': 79.77571720232172, 'Small Intestine': 71.7519320855615, 'Spleen': 10.061029045643156, 'Stomach': 58.07813805013927, 'Testis': 0.8144204986149585, 'Thyroid': 135.176797856049, 'Uterus': 1.442593943661972, 'Vagina': 86.52345512820513}
NUSAP1
MIIPSLEELDSLKYSDLQNLAKSLGLRANLRATKLLKALKGYIKHEARKGNENQDESQTSASSCDETEIQISNQEEAERQPLGHVTKTRRRCKTVRVDPDSQNHSEIKISNPTEFQNHEKQESQDLRATAKVPSPPDEHQEAENAVSSGNRDSKVPSEGKKSLYTDESSKPGKNKRTAITTPNFKKLHEAHFKEMESIDQYIERKKKHFEEHNSMNELKQQPINKGGVRTPVPPRGRLSVASTPISQRRSQGRSCGPASQSTLGLKGSLKRSAISAAKTGVRFSAATKDNEHKRSLTKTPARKSAHVTVSGGTPKGEAVLGTHKLKTITGNSAAVITPFKLTTEATQTPVSNKKPVFDLKASLSRPLNYEPHKGKLKPWGQSKENNYLNQHVNRINFYKKTYKQPHLQTKEEQRKKREQERKEKKAKVLGMRRGLILAED
Homo sapiens
null
Not found
{}
null
{'Adipose Tissue': 3.0626249169435216, 'Adrenal Gland': 20.066418604651165, 'Bladder': 2.5714285714285716, 'Blood': 38.67838557588806, 'Blood Vessel': 1.907438127340824, 'Brain': 0.921281385314156, 'Breast': 2.6828954248366013, 'Cervix Uteri': 4.126584210526316, 'Colon': 5.369006418485237, 'Esophagus': 10.88004830449827, 'Fallopian Tube': 2.6983444444444444, 'Heart': 0.9591686178861788, 'Kidney': 2.958684269662921, 'Liver': 3.8981778761061943, 'Lung': 8.120652249134949, 'Muscle': 4.355879825653798, 'Nerve': 2.3376048465266557, 'Ovary': 9.89653888888889, 'Pancreas': 1.0126895426829268, 'Pituitary': 1.4382194346289752, 'Prostate': 2.505309795918367, 'Salivary Gland': 5.667204320987654, 'Skin': 27.983096738529575, 'Small Intestine': 12.297466310160427, 'Spleen': 13.0189377593361, 'Stomach': 6.007349025069638, 'Testis': 25.17539335180055, 'Thyroid': 2.2111070444104137, 'Uterus': 2.285015492957746, 'Vagina': 12.095448076923075}
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73.27, 70.36, 72.63, 72.69, 68.11, 66.06, 60.67, 52.64, 44.07, 48.46, 43.79, 36.31]
[1.0, 1.0, 1.0, 1.0, 0.98, 1.0, 0.91, 0.96, 0.9, 0.88, 1.0, 1.0, 1.0, 1.0, 1.0, 0.87, 0.99, 0.76, 0.96, 1.0, 0.98, 0.95, 0.93, 0.92, 0.87, 0.92, 0.69, 0.71, 0.79, 0.3, 0.2, 0.17, 0.63, 0.32, 0.89, 0.66, 0.1, 0.62, 0.15, 0.67, 0.03, 0.67, 0.77, 0.54, 0.57, 0.04, 0.68, 0.73, 0.54, 0.54, 0.59, 0.08, 0.19, 0.61, 0.0, 0.39, 0.06, 0.63, 0.14, 0.63, 0.49, 0.83, 0.72, 0.93, 0.78, 0.07, 0.63, 0.12, 0.52, 0.15, 0.6, 0.19, 0.51, 0.41, 0.03, 0.62, 0.11, 0.3, 0.46, 0.47, 0.0, 0.23, 0.0, 0.24, 0.03, 0.5, 0.67, 0.61, 0.06, 0.78, 0.04, 0.83, 0.7, 0.57, 0.54, 0.13, 0.52, 0.06, 0.45, 0.0, 0.11, 0.0, 0.38, 0.12, 0.54, 0.79, 0.81, 0.65, 0.6, 0.24, 0.6, 0.01, 0.47, 0.01, 0.12, 0.0, 0.25, 0.26, 0.46, 0.93, 0.85, 0.99, 0.94, 1.0, 0.91, 0.99, 0.99, 0.98, 1.0, 1.0, 1.0, 1.0, 0.99, 0.98, 0.98, 0.92, 0.93, 0.87, 0.82, 0.85, 0.76, 0.9, 0.91, 0.9, 0.93, 0.65, 0.96, 0.84, 0.86, 0.96, 0.99, 0.96, 0.7, 0.92, 0.89, 0.8, 0.83, 0.23, 0.86, 0.73, 0.12, 0.62, 0.06, 0.4, 0.02, 0.42, 0.35, 0.9, 0.64, 0.82, 0.29, 0.51, 0.17, 0.54, 0.27, 0.29, 0.51, 0.08, 0.77, 0.06, 0.62, 0.39, 0.34, 0.94, 0.83, 0.46, 0.51, 0.07, 0.17, 0.07, 0.41, 0.14, 0.31, 0.2, 0.36, 0.0, 0.13, 0.59, 0.53, 0.77, 0.2, 0.64, 0.35, 0.0, 0.02, 0.39, 0.18, 0.39, 0.57, 0.63, 0.39, 0.0, 0.32, 0.0, 0.18, 0.03, 0.29, 0.47, 0.55, 0.03, 0.34, 0.2, 0.45, 0.56, 0.17, 0.37, 0.59, 0.01, 0.39, 0.0, 0.39, 0.05, 0.28, 0.07, 0.29, 0.26, 0.64, 0.82, 0.64, 0.63, 0.76, 0.15, 0.39, 0.95, 0.57, 0.28, 0.58, 0.02, 0.43, 0.0, 0.29, 0.09, 0.4, 0.13, 0.49, 0.31, 0.53, 0.32, 0.66, 0.01, 0.71, 0.13, 0.56, 0.54, 0.84, 0.51, 0.06, 0.82, 0.14, 0.54, 0.07, 0.63, 0.05, 0.7, 0.17, 0.75, 0.51, 0.64, 0.36, 0.67, 0.15, 0.12, 0.61, 0.0, 0.33, 0.14, 0.62, 0.2, 0.52, 0.05, 0.14, 0.63, 0.95, 0.85, 0.32, 0.6, 0.1, 0.12, 0.17, 0.17, 0.06, 0.08, 0.41, 0.28, 0.55, 0.49, 0.09, 0.68, 0.23, 0.53, 0.64, 0.52, 0.42, 0.64, 0.64, 0.0, 0.08, 0.44, 0.13, 0.48, 0.52, 0.81, 0.44, 0.0, 0.26, 0.0, 0.21, 0.03, 0.46, 0.27, 0.71, 0.45, 0.06, 0.28, 0.28, 0.4, 0.65, 0.28, 0.46, 0.61, 0.0, 0.36, 0.0, 0.32, 0.01, 0.22, 0.0, 0.05, 0.0, 0.41, 0.46, 0.42, 0.82, 0.48, 0.4, 0.5, 0.17, 0.62, 0.06, 0.32, 0.0, 0.25, 0.0, 0.42, 0.08, 0.41, 0.27, 0.16, 0.04, 0.36, 0.32, 0.2, 0.0, 0.52, 0.04, 0.66, 0.47, 0.52, 0.78, 0.09, 0.77, 0.08, 0.6, 0.0, 0.31, 0.03, 0.58, 0.47, 0.59, 0.44, 0.23, 0.54, 0.1, 0.18, 0.45, 0.0, 0.53, 0.11, 0.59, 0.17, 0.51, 0.01, 0.19, 0.71, 0.77, 0.3, 0.44, 0.08, 0.14, 0.52, 0.05, 0.37, 0.1, 0.42, 0.23, 0.61, 0.43, 0.22, 0.96, 0.54, 0.4, 0.3, 0.07, 0.39, 0.17, 0.43, 0.38, 0.3, 0.8, 0.83, 0.44, 0.03, 0.11, 0.0, 0.23, 0.0, 0.31, 0.0, 0.38, 0.58, 0.51, 0.01, 0.49, 0.13, 0.26, 0.69, 0.46, 0.41, 0.51, 0.06, 0.51, 0.03, 0.38, 0.0, 0.06, 0.0, 0.34, 0.08, 0.53, 0.42, 0.88, 0.25, 0.75, 0.49, 1.0, 0.34, 0.86, 0.48, 0.18, 0.52, 0.01, 0.32, 0.0, 0.19, 0.0, 0.3, 0.05, 0.44, 0.27, 0.43, 0.11, 0.31, 0.39, 0.03, 0.55, 0.04, 0.52, 0.51, 0.64, 0.57, 0.19, 0.68, 0.13, 0.84, 0.06, 0.31, 0.07, 0.69, 0.26, 0.37, 0.53, 0.67, 0.5, 0.56, 0.14, 0.18, 0.47, 0.01, 0.47, 0.15, 0.61, 0.28, 0.2, 0.02, 0.76, 0.55, 0.31, 0.94, 0.22, 0.57, 0.17, 0.4, 0.07, 0.5, 0.31, 0.7, 0.2, 0.14, 0.3, 0.23, 0.58, 0.07, 0.06, 0.55, 0.15, 0.46, 0.43, 0.64, 0.53, 0.0, 0.18, 0.01, 0.23, 0.02, 0.63, 0.33, 0.79, 0.06, 0.38, 0.07, 0.14, 0.23, 0.68, 0.89, 0.29, 0.06, 0.72, 0.92, 0.24, 0.25, 0.0, 0.46, 0.02, 0.21, 0.01, 0.06, 0.0, 0.05, 0.07, 0.61, 0.17, 0.89, 0.72, 0.66, 0.14, 0.52, 0.07, 0.58, 0.01, 0.26, 0.0, 0.13, 0.0, 0.29, 0.04, 0.46, 0.27, 0.28, 0.23, 0.56, 0.32, 0.25, 0.0, 0.33, 0.05, 0.55, 0.5, 0.58, 0.53, 0.04, 0.27, 0.02, 0.04, 0.37, 0.67, 0.74, 0.35, 0.62, 0.54, 0.26, 0.46, 0.0, 0.47, 0.09, 0.45, 0.15, 0.39, 0.05, 0.44, 0.85, 0.56, 0.11, 0.11, 0.35, 0.42, 0.03, 0.32, 0.12, 0.49, 0.19, 0.25, 0.8, 0.6, 0.09, 0.49, 0.57, 0.36, 0.04, 0.35, 0.28, 0.52, 0.39, 0.5, 0.28, 0.93, 0.47, 0.3, 0.47, 0.08, 0.02, 0.18, 0.01, 0.34, 0.23, 0.55, 0.57, 0.91, 0.1, 0.78, 0.52, 0.34, 0.61, 0.24, 0.75, 0.0, 0.2, 0.02, 0.24, 0.0, 0.18, 0.04, 0.44, 0.59, 0.71, 0.29, 0.52, 0.37, 0.5, 0.11, 0.6, 0.02, 0.48, 0.01, 0.16, 0.04, 0.35, 0.66, 0.47, 0.74, 0.14, 0.62, 0.16, 0.77, 0.79, 0.27, 0.93, 0.69, 0.88, 0.88, 0.85, 0.87, 0.91, 0.92, 0.82, 0.63, 0.75, 0.7, 0.7, 0.38, 0.43, 0.64, 0.55, 0.54, 0.59, 0.45, 0.47, 0.5, 0.58, 0.52, 0.61, 0.57, 0.52, 0.68, 0.44, 0.6, 0.61, 0.58, 0.55, 0.5, 0.61, 0.61, 0.86, 0.86, 0.75, 0.91, 0.96, 0.93, 1.0, 0.87, 0.97, 0.91, 0.95, 0.86, 0.98, 0.93, 0.88, 0.59, 0.87, 0.7, 0.67, 0.85, 0.89, 0.88, 0.91, 0.93, 0.88, 0.99, 0.92, 1.0, 0.79, 0.9, 1.0, 0.94, 1.0, 0.97, 0.96, 0.9, 0.63, 0.68, 0.48, 0.54, 0.8, 0.7, 0.7, 0.95, 0.87, 0.77, 0.84, 0.79, 0.89, 0.95, 0.8, 0.77, 0.51, 0.87, 0.7, 0.52, 0.84, 0.91, 0.51, 0.96, 0.79, 0.92, 0.84, 0.21, 0.89, 0.53, 0.52, 0.89, 0.86, 0.26, 0.91, 0.45, 0.68, 0.84, 0.48, 0.44, 0.51, 0.62, 0.28, 0.59, 0.63, 0.57, 0.15, 0.55, 0.66, 0.1, 0.38, 0.74, 0.65, 0.17, 0.43, 0.66, 0.41, 0.8, 0.75, 0.9, 0.93, 0.52, 0.76, 0.89, 0.87, 0.76, 0.92, 0.91, 0.75, 0.61, 0.96, 0.89, 0.73, 0.97, 0.68, 0.87, 0.55, 0.85, 0.77, 0.69, 0.76, 0.98, 0.83, 0.68, 0.82, 0.74, 0.65, 0.96, 0.93, 0.54, 0.64, 0.28, 0.54, 0.52, 0.16, 0.51, 0.88, 0.6, 0.4, 0.88, 0.95, 0.33, 0.56, 0.73, 0.39, 0.06, 0.61, 0.75, 0.47, 0.19, 0.87, 0.7, 0.97, 0.94, 0.97]
null
null
null
Component of an E-cadherin/ catenin adhesion complex composed of at least E-cadherin/CDH1, beta-catenin/CTNNB1 or gamma-catenin/JUP, and potentially alpha-catenin/CTNNA1. Forms a ternary complex composed of ADAM10, CADH1 and EPHA4,
null
null
KLRG1, SPEF1, DLGAP5, AJAP1, RAPGEF2, RAB8B, PIP5K1C, PKP2, TRPV4, CTNNB1, CAV1, DDR1, TBC1D2, CTNNA1, JUP, CTNND1, PSEN1, LIMA1, CDH1, JUP, ADAM10, CADH1 , EPHA4,
null
null
null
null
Homodimer
null
79.91949
0.474025
null
null
1,804
P12830
Q9H467
null
degron_data
CDH1
MGPWSRSLSALLLLLQVSSWLCQEPEPCHPGFDAESYTFTVPRRHLERGRVLGRVNFEDCTGRQRTAYFSLDTRFKVGTDGVITVKRPLRFHNPQIHFLVYAWDSTYRKFSTKVTLNTVGHHHRPPPHQASVSGIQAELLTFPNSSPGLRRQKRDWVIPPISCPENEKGPFPKNLVQIKSNKDKEGKVFYSITGQGADTPPVGVFIIERETGWLKVTEPLDRERIATYTLFSHAVSSNGNAVEDPMEILITVTDQNDNKPEFTQEVFKGSVMEGALPGTSVMEVTATDADDDVNTYNAAIAYTILSQDPELPDKNMFTINRNTGVISVVTTGLDRESFPTYTLVVQAADLQGEGLSTTATAVITVTDTNDNPPIFNPTTYKGQVPENEANVVITTLKVTDADAPNTPAWEAVYTILNDDGGQFVVTTNPVNNDGILKTAKGLDFEAKQQYILHVAVTNVVPFEVSLTTSTATVTVDVLDVNEAPIFVPPEKRVEVSEDFGVGQEITSYTAQEPDTFMEQKITYRIWRDTANWLEINPDTGAISTRAELDREDFEHVKNSTYTALIIATDNGSPVATGTGTLLLILSDVNDNAPIPEPRTIFFCERNPKPQVINIIDADLPPNTSPFTAELTHGASANWTIQYNDPTQESIILKPKMALEVGDYKINLKLMDNQNKDQVTTLEVSVCDCEGAAGVCRKAQPVEAGLQIPAILGILGGILALLILILLLLLFLRRRAVVKEPLLPPEDDTRDNVYYYDEEGGGEEDQDFDLSQLHRGLDARPEVTRNDVAPTLMSVPRYLPRPANPDEIGNFIDENLKAADTDPTAPPYDSLLVFDYEGSGSEAASLSSLNSSESDKDQDYDYLNEWGNRFKKLADMYGGGEDD
Homo sapiens
Cell junction, adherens junction, Cell membrane, Endosome, Golgi apparatus, trans-Golgi network, Cytoplasm, Cell junction, desmosome
Tissue enhanced (parathyroid)
{'Ciliated cells': '119.1', 'Basal respiratory cells': '71.1', 'Club cells': '97.3', 'Ionocytes': '81.0', 'Mucus glandular cells': '155.0', 'Serous glandular cells': '67.8', 'Gastric mucus-secreting cells': '133.2', 'Proximal enterocytes': '140.9', 'Paneth cells': '125.1', 'Distal enterocytes': '307.5', 'Intestinal goblet cells': '173.5', 'Exocrine glandular cells': '-0.605', 'Basal prostatic cells': '68.3', 'Prostatic glandular cells': '186.7', 'Breast glandular cells': '0.773', 'Breast myoepithelial cells': '0.700', 'Glandular and luminal cells': '313.0', 'Secretory cells': '82.3', 'Basal keratinocytes': '102.5', 'Suprabasal keratinocytes': '162.6', 'Basal squamous epithelial cells': '51.0', 'Squamous epithelial cells': '106.9', 'Alveolar cells type 1': '0.437', 'Alveolar cells type 2': '0.706', 'Salivary duct cells': '95.9', 'Ductal cells': '0.541', 'Hepatocytes': '0.600', 'Cholangiocytes': '129.7', 'Proximal tubular cells': '0.042', 'Distal tubular cells': '0.0', 'Collecting duct cells': '143.9', 'Mesothelial cells': '0.799', 'Sertoli cells': '0.252', 'Granulosa cells': '12.9', 'Enteroendocrine cells': '92.4', 'Pancreatic endocrine cells': '78.1', 'Leydig cells': '0.264', 'Excitatory neurons': '0.7', 'Inhibitory neurons': '1.3', 'Cone photoreceptor cells': '0.0', 'Rod photoreceptor cells': '0.0', 'Bipolar cells': '0.2', 'Horizontal cells': '0.6', 'Astrocytes': '0.6', 'Oligodendrocyte precursor cells': '0.5', 'Oligodendrocytes': '29.9', 'Microglial cells': '0.9', 'Muller glia cells': '0.1', 'Schwann cells': '0.131', 'Spermatogonia': '0.392', 'Spermatocytes': '0.193', 'Early spermatids': '-0.217', 'Late spermatids': '-0.290', 'Oocytes': '16.9', 'Cytotrophoblasts': '119.2', 'Syncytiotrophoblasts': '45.0', 'Extravillous trophoblasts': '24.9', 'Endothelial cells': '6.1', 'Lymphatic endothelial cells': '0.4', 'Cardiomyocytes': '0.135', 'Skeletal myocytes': '0.107', 'Smooth muscle cells': '5.8', 'Adipocytes': '2.1', 'Melanocytes': '0.335', 'Fibroblasts': '6.5', 'Peritubular cells': '0.210', 'Endometrial stromal cells': '27.7', 'Ovarian stromal cells': '0.7', 'Undifferentiated cells': '101.6', 'T-cells': '2.9', 'B-cells': '4.4', 'Plasma cells': '6.1', 'Nk-cells': '0.0', 'Granulocytes': '8.4', 'Monocytes': '0.0', 'Macrophages': '6.0', 'Hofbauer cells': '4.3', 'Kupffer cells': '1.0', 'Dendritic cells': '5.9', 'Langerhans cells': '0.304', 'Erythroid cells': '0.036', 'Adipocytes (Subcutaneous)': '-0.081', 'Adipocytes (Visceral)': '-0.209', 'Breast glandular cells (progenitors)': '0.538', 'Adipocytes (Breast)': '-0.689', 'Colon enterocytes': '0.790', 'Colon enteroendocrine cells': '0.112', 'Enteric glia cells': '-0.048', 'Mitotic cells (Colon)': '0.299', 'Mitotic cells (Heart)': '0.120', 'Podocytes': '-0.118', 'Ascending Loop of Henle cells': '0.475', 'Intercalated cells': '0.212', 'Cholangiocyte': '0.090', 'NK-cells (Liver)': '-0.005', 'Respiratory ciliated cells': '-0.012', 'Mitotic cells (Lung)': '0.071', 'NK-cells (Lung)': '-0.266', 'B-cells (Lung)': '-0.296', 'Alpha cells': '0.270', 'Beta cells': '0.152', 'Prostate glandular cells': '0.764', 'Prostate basal glandular cells': '0.540', 'Urothelial cells': '0.205', 'Keratinocyte (other)': '0.510', 'Keratinocyte (granular)': '0.055', 'Hair cortex cells': '0.080', 'Inner root sheath cells': '0.131', 'Outer root sheath cells': '0.175', 'Sebaceous gland cells': '0.156', 'Eccrine sweat gland cells': '-0.207', 'Adipocytes (Skin)': '-0.244', 'Mitotic cells (Skin)': '0.442', 'Parietal cells': '0.654', 'Chief cells': '0.649', 'Gastric mucous cells': '0.781', 'Gastric enteroendocrine cells': '0.590', 'Mitotic cells (Stomach)': '0.445', 'Parafollicular cells': '0.173', 'Thyroid glandular cells': '0.865', 'Mitotic cells (Thyroid)': '-0.081', 'Adrenal cortex cells': '0.051', 'Adrenal medulla cells': '0.087', 'Mitotic cells (Adrenal gland)': '0.072', 'Minor salivary glandular cells': '0.371', 'Minor salivary gland ductal cells': '-0.142', 'Minor salivary gland basal cells': '0.582', 'Mitotic cells (Minor salivary gland)': '0.567', 'Adipocytes (Minor salivary gland)': '0.050', 'Somatotropes': '0.121', 'Lactotropes': '0.322', 'Gonadotropes': '0.330', 'Corticotropes': '0.180', 'Thyrotropes': '0.496', 'Undifferentiated cells (Pituitary gland)': '-0.108', 'Mitotic cells (Spleen)': '-0.228', 'Platelets': '-0.050', 'Erythrocytes': '-0.158', 'Hematopoietic stem cells': '-0.211', 'B-cells (Spleen)': '0.266', 'NK-cells (Spleen)': '0.309', 'Amygdala excitatory': '1.0', 'Cerebellar inhibitory': '0.9', 'Cge interneuron': '0.7', 'Deep-layer corticothalamic and 6b': '1.5', 'Deep-layer intratelencephalic': '0.7', 'Deep-layer near-projecting': '0.7', 'Eccentric medium spiny neuron': '0.6', 'Hippocampal ca1-3': '1.9', 'Hippocampal ca4': '1.2', 'Hippocampal dentate gyrus': '1.1', 'Lamp5-lhx6 and chandelier': '0.5', 'Lower rhombic lip': '0.8', 'Mammillary body': '0.6', 'Medium spiny neuron': '0.7', 'Mge interneuron': '1.7', 'Midbrain-derived inhibitory': '0.7', 'Miscellaneous': '0.9', 'Splatter': '3.8', 'Thalamic excitatory': '0.5', 'Upper rhombic lip': '0.8', 'Upper-layer intratelencephalic': '0.6', 'Astrocyte': '4.4', 'Bergmann glia': '0.2', 'Central nervous system macrophage': '0.6', 'Choroid plexus epithelial cell': '52.1', 'Committed oligodendrocyte precursor': '41.5', 'Ependymal cell': '4.8', 'Oligodendrocyte': '53.1', 'Oligodendrocyte precursor cell': '2.4', 'Endothelial cell': '0.7', 'Pericyte': '0.3', 'Vascular associated smooth muscle cell': '0.0', 'Fibroblast': '17.4', 'Leukocyte': '1.1', 'Basophil': '0.0', 'Eosinophil': '0.0', 'Neutrophil': '0.0', 'Classical monocyte': '0.0', 'Non-classical monocyte': '0.0', 'Intermediate monocyte': '0.0', 'T-reg': '2.3', 'GdT-cell': '0.0', 'MAIT T-cell': '0.0', 'Memory CD4 T-cell': '0.0', 'Naive CD4 T-cell': '0.1', 'Memory CD8 T-cell': '0.2', 'Naive CD8 T-cell': '0.3', 'Memory B-cell': '0.0', 'Naive B-cell': '0.1', 'Plasmacytoid DC': '46.6', 'Myeloid DC': '8.5', 'NK-cell': '0.1', 'Total PBMC': '0.7', 'Vd2 gdTCR': '0.0', 'Memory CD4 T-cell Th1\\/Th17': '0.1', 'Memory CD4 T-cell Th17': '0.2', 'Memory CD4 T-cell Th2': '2.9', 'Non-Vd2 gdTCR': '0.1', 'Memory CD4 T-cell Th1': '0.3', 'Memory CD4 T-cell TFH': '0.5', 'Terminal effector memory CD4 T-cell': '0.0', 'Central memory CD8 T-cell': '4.8', 'Effector memory CD8 T-cell': '0.0', 'Terminal effector memory CD8 T-cell': '0.6', 'Non-switched memory B-cell': '0.0', 'Plasmablast': '3.3', 'Switched memory B-cell': '0.0', 'Exhausted memory B-cell': '0.7', 'Progenitor cell': '2.3', 'Memory T-reg': '1.3', 'Naive CD4 T-cell activated': '0.3', 'Naive CD8 T-cell activated': '0.6', 'Naive T-reg': '0.1'}
1O6S, 2O72, 2OMT, 2OMU, 2OMV, 2OMX, 2OMY, 2OMZ, 3FF7, 3FF8, 3L6X, 3L6Y, 4ZT1, 4ZTE, 6CXY, 6OLE, 6OLF, 6OLG, 6VEL, 7STZ, 8H62
{'Adipose Tissue': 1.2125261088039867, 'Adrenal Gland': 0.1914223992248062, 'Bladder': 39.2033519047619, 'Blood': 1.340954264800861, 'Blood Vessel': 0.3121561692883895, 'Brain': 0.8550442199091597, 'Breast': 38.54918344226579, 'Cervix Uteri': 23.539115789473684, 'Colon': 43.41292142490372, 'Esophagus': 53.97513367404844, 'Fallopian Tube': 14.900277777777776, 'Heart': 0.119140469221835, 'Kidney': 25.040449438202245, 'Liver': 26.60802654867257, 'Lung': 35.447986366782004, 'Muscle': 0.1378936151930261, 'Nerve': 17.518468982229404, 'Ovary': 3.6515122222222223, 'Pancreas': 56.89676829268293, 'Pituitary': 24.68741660777385, 'Prostate': 61.279967346938776, 'Salivary Gland': 92.01685185185184, 'Skin': 79.77571720232172, 'Small Intestine': 71.7519320855615, 'Spleen': 10.061029045643156, 'Stomach': 58.07813805013927, 'Testis': 0.8144204986149585, 'Thyroid': 135.176797856049, 'Uterus': 1.442593943661972, 'Vagina': 86.52345512820513}
CUEDC2
MELERIVSAALLAFVQTHLPEADLSGLDEVIFSYVLGVLEDLGPSGPSEENFDMEAFTEMMEAYVPGFAHIPRGTIGDMMQKLSGQLSDARNKENLQPQSSGVQGQVPISPEPLQRPEMLKEETRSSAAAAADTQDEATGAEEELLPGVDVLLEVFPTCSVEQAQWVLAKARGDLEEAVQMLVEGKEEGPAAWEGPNQDLPRRLRGPQKDELKSFILQKYMMVDSAEDQKIHRPMAPKEAPKKLIRYIDNQVVSTKGERFKDVRNPEAEEMKATYINLKPARKYRFH
Homo sapiens
Cytoplasm, Nucleus
Low tissue specificity
{'Ciliated cells': '35.9', 'Basal respiratory cells': '69.2', 'Club cells': '41.5', 'Ionocytes': '43.1', 'Mucus glandular cells': '40.5', 'Serous glandular cells': '31.0', 'Gastric mucus-secreting cells': '29.5', 'Proximal enterocytes': '31.1', 'Paneth cells': '39.2', 'Distal enterocytes': '20.4', 'Intestinal goblet cells': '29.0', 'Exocrine glandular cells': '-0.712', 'Basal prostatic cells': '38.7', 'Prostatic glandular cells': '45.1', 'Breast glandular cells': '0.338', 'Breast myoepithelial cells': '0.230', 'Glandular and luminal cells': '29.6', 'Secretory cells': '68.3', 'Basal keratinocytes': '37.4', 'Suprabasal keratinocytes': '30.9', 'Basal squamous epithelial cells': '42.3', 'Squamous epithelial cells': '39.9', 'Alveolar cells type 1': '-0.148', 'Alveolar cells type 2': '-0.145', 'Salivary duct cells': '38.4', 'Ductal cells': '0.576', 'Hepatocytes': '0.508', 'Cholangiocytes': '32.4', 'Proximal tubular cells': '0.222', 'Distal tubular cells': '52.2', 'Collecting duct cells': '38.9', 'Mesothelial cells': '0.472', 'Sertoli cells': '0.066', 'Granulosa cells': '72.3', 'Enteroendocrine cells': '55.7', 'Pancreatic endocrine cells': '61.1', 'Leydig cells': '0.008', 'Excitatory neurons': '11.8', 'Inhibitory neurons': '15.4', 'Cone photoreceptor cells': '62.9', 'Rod photoreceptor cells': '32.6', 'Bipolar cells': '53.1', 'Horizontal cells': '49.7', 'Astrocytes': '10.2', 'Oligodendrocyte precursor cells': '12.7', 'Oligodendrocytes': '21.8', 'Microglial cells': '3.6', 'Muller glia cells': '85.1', 'Schwann cells': '0.088', 'Spermatogonia': '0.062', 'Spermatocytes': '0.027', 'Early spermatids': '0.117', 'Late spermatids': '-0.031', 'Oocytes': '33.1', 'Cytotrophoblasts': '68.3', 'Syncytiotrophoblasts': '39.1', 'Extravillous trophoblasts': '32.4', 'Endothelial cells': '45.2', 'Lymphatic endothelial cells': '65.0', 'Cardiomyocytes': '0.761', 'Skeletal myocytes': '0.174', 'Smooth muscle cells': '61.9', 'Adipocytes': '54.5', 'Melanocytes': '0.117', 'Fibroblasts': '56.8', 'Peritubular cells': '-0.008', 'Endometrial stromal cells': '53.2', 'Ovarian stromal cells': '87.9', 'Undifferentiated cells': '53.2', 'T-cells': '34.0', 'B-cells': '30.9', 'Plasma cells': '47.0', 'Nk-cells': '32.6', 'Granulocytes': '38.4', 'Monocytes': '29.3', 'Macrophages': '42.3', 'Hofbauer cells': '81.9', 'Kupffer cells': '40.7', 'Dendritic cells': '41.4', 'Langerhans cells': '0.149', 'Erythroid cells': '-0.011', 'Adipocytes (Subcutaneous)': '-0.069', 'Adipocytes (Visceral)': '-0.132', 'Breast glandular cells (progenitors)': '0.230', 'Adipocytes (Breast)': '-0.167', 'Colon enterocytes': '-0.333', 'Colon enteroendocrine cells': '0.193', 'Enteric glia cells': '0.315', 'Mitotic cells (Colon)': '-0.252', 'Mitotic cells (Heart)': '0.431', 'Podocytes': '-0.059', 'Ascending Loop of Henle cells': '0.485', 'Intercalated cells': '0.044', 'Cholangiocyte': '0.386', 'NK-cells (Liver)': '-0.303', 'Respiratory ciliated cells': '-0.025', 'Mitotic cells (Lung)': '0.205', 'NK-cells (Lung)': '-0.130', 'B-cells (Lung)': '-0.154', 'Alpha cells': '0.425', 'Beta cells': '0.248', 'Prostate glandular cells': '0.012', 'Prostate basal glandular cells': '0.049', 'Urothelial cells': '-0.058', 'Keratinocyte (other)': '-0.158', 'Keratinocyte (granular)': '-0.181', 'Hair cortex cells': '0.192', 'Inner root sheath cells': '0.130', 'Outer root sheath cells': '0.258', 'Sebaceous gland cells': '0.060', 'Eccrine sweat gland cells': '0.182', 'Adipocytes (Skin)': '0.220', 'Mitotic cells (Skin)': '0.100', 'Parietal cells': '-0.715', 'Chief cells': '-0.532', 'Gastric mucous cells': '-0.488', 'Gastric enteroendocrine cells': '-0.456', 'Mitotic cells (Stomach)': '-0.023', 'Parafollicular cells': '0.115', 'Thyroid glandular cells': '0.480', 'Mitotic cells (Thyroid)': '-0.012', 'Adrenal cortex cells': '0.426', 'Adrenal medulla cells': '0.042', 'Mitotic cells (Adrenal gland)': '0.406', 'Minor salivary glandular cells': '0.534', 'Minor salivary gland ductal cells': '0.074', 'Minor salivary gland basal cells': '0.019', 'Mitotic cells (Minor salivary gland)': '0.225', 'Adipocytes (Minor salivary gland)': '0.165', 'Somatotropes': '-0.146', 'Lactotropes': '-0.084', 'Gonadotropes': '0.004', 'Corticotropes': '-0.161', 'Thyrotropes': '0.142', 'Undifferentiated cells (Pituitary gland)': '0.469', 'Mitotic cells (Spleen)': '-0.384', 'Platelets': '-0.150', 'Erythrocytes': '-0.046', 'Hematopoietic stem cells': '-0.158', 'B-cells (Spleen)': '0.175', 'NK-cells (Spleen)': '0.150', 'Amygdala excitatory': '14.2', 'Cerebellar inhibitory': '31.1', 'Cge interneuron': '27.2', 'Deep-layer corticothalamic and 6b': '17.2', 'Deep-layer intratelencephalic': '18.0', 'Deep-layer near-projecting': '20.4', 'Eccentric medium spiny neuron': '15.6', 'Hippocampal ca1-3': '18.0', 'Hippocampal ca4': '23.0', 'Hippocampal dentate gyrus': '20.8', 'Lamp5-lhx6 and chandelier': '27.5', 'Lower rhombic lip': '30.2', 'Mammillary body': '18.4', 'Medium spiny neuron': '14.0', 'Mge interneuron': '22.4', 'Midbrain-derived inhibitory': '25.5', 'Miscellaneous': '20.1', 'Splatter': '21.6', 'Thalamic excitatory': '22.0', 'Upper rhombic lip': '31.3', 'Upper-layer intratelencephalic': '16.6', 'Astrocyte': '19.7', 'Bergmann glia': '29.8', 'Central nervous system macrophage': '15.3', 'Choroid plexus epithelial cell': '17.5', 'Committed oligodendrocyte precursor': '45.1', 'Ependymal cell': '22.4', 'Oligodendrocyte': '37.0', 'Oligodendrocyte precursor cell': '30.9', 'Endothelial cell': '21.4', 'Pericyte': '35.2', 'Vascular associated smooth muscle cell': '23.9', 'Fibroblast': '17.8', 'Leukocyte': '13.8', 'Basophil': '44.9', 'Eosinophil': '84.6', 'Neutrophil': '39.3', 'Classical monocyte': '70.0', 'Non-classical monocyte': '41.1', 'Intermediate monocyte': '70.6', 'T-reg': '53.0', 'GdT-cell': '69.3', 'MAIT T-cell': '57.1', 'Memory CD4 T-cell': '67.1', 'Naive CD4 T-cell': '47.4', 'Memory CD8 T-cell': '72.4', 'Naive CD8 T-cell': '66.4', 'Memory B-cell': '80.9', 'Naive B-cell': '37.9', 'Plasmacytoid DC': '83.0', 'Myeloid DC': '93.7', 'NK-cell': '66.2', 'Total PBMC': '86.0', 'Vd2 gdTCR': '65.5', 'Memory CD4 T-cell Th1\\/Th17': '54.0', 'Memory CD4 T-cell Th17': '64.9', 'Memory CD4 T-cell Th2': '63.2', 'Non-Vd2 gdTCR': '57.4', 'Memory CD4 T-cell Th1': '68.6', 'Memory CD4 T-cell TFH': '78.9', 'Terminal effector memory CD4 T-cell': '42.5', 'Central memory CD8 T-cell': '50.8', 'Effector memory CD8 T-cell': '49.0', 'Terminal effector memory CD8 T-cell': '58.4', 'Non-switched memory B-cell': '67.5', 'Plasmablast': '66.3', 'Switched memory B-cell': '54.6', 'Exhausted memory B-cell': '49.5', 'Progenitor cell': '69.2', 'Memory T-reg': '84.7', 'Naive CD4 T-cell activated': '22.9', 'Naive CD8 T-cell activated': '39.4', 'Naive T-reg': '52.0'}
null
{'Adipose Tissue': 70.20386212624584, 'Adrenal Gland': 83.49833333333333, 'Bladder': 83.17380952380952, 'Blood': 47.83628417653391, 'Blood Vessel': 86.22140823970038, 'Brain': 74.94496971990915, 'Breast': 71.57019607843138, 'Cervix Uteri': 99.97947368421052, 'Colon': 81.23830551989731, 'Esophagus': 73.35456747404845, 'Fallopian Tube': 100.01222222222222, 'Heart': 55.277292682926834, 'Kidney': 55.67651685393258, 'Liver': 29.18770353982301, 'Lung': 72.19313148788927, 'Muscle': 69.41124533001246, 'Nerve': 192.85720516962843, 'Ovary': 106.9572222222222, 'Pancreas': 25.875807926829268, 'Pituitary': 81.85802120141342, 'Prostate': 86.8814693877551, 'Salivary Gland': 52.31728395061728, 'Skin': 73.06685461580985, 'Small Intestine': 55.73283422459893, 'Spleen': 72.95228215767635, 'Stomach': 59.63924791086352, 'Testis': 80.23013850415514, 'Thyroid': 87.14828483920368, 'Uterus': 108.33161971830988, 'Vagina': 68.53641025641026}
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73.27, 70.36, 72.63, 72.69, 68.11, 66.06, 60.67, 52.64, 44.07, 48.46, 43.79, 36.31]
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0.54, 0.27, 0.29, 0.51, 0.08, 0.77, 0.06, 0.62, 0.39, 0.34, 0.94, 0.83, 0.46, 0.51, 0.07, 0.17, 0.07, 0.41, 0.14, 0.31, 0.2, 0.36, 0.0, 0.13, 0.59, 0.53, 0.77, 0.2, 0.64, 0.35, 0.0, 0.02, 0.39, 0.18, 0.39, 0.57, 0.63, 0.39, 0.0, 0.32, 0.0, 0.18, 0.03, 0.29, 0.47, 0.55, 0.03, 0.34, 0.2, 0.45, 0.56, 0.17, 0.37, 0.59, 0.01, 0.39, 0.0, 0.39, 0.05, 0.28, 0.07, 0.29, 0.26, 0.64, 0.82, 0.64, 0.63, 0.76, 0.15, 0.39, 0.95, 0.57, 0.28, 0.58, 0.02, 0.43, 0.0, 0.29, 0.09, 0.4, 0.13, 0.49, 0.31, 0.53, 0.32, 0.66, 0.01, 0.71, 0.13, 0.56, 0.54, 0.84, 0.51, 0.06, 0.82, 0.14, 0.54, 0.07, 0.63, 0.05, 0.7, 0.17, 0.75, 0.51, 0.64, 0.36, 0.67, 0.15, 0.12, 0.61, 0.0, 0.33, 0.14, 0.62, 0.2, 0.52, 0.05, 0.14, 0.63, 0.95, 0.85, 0.32, 0.6, 0.1, 0.12, 0.17, 0.17, 0.06, 0.08, 0.41, 0.28, 0.55, 0.49, 0.09, 0.68, 0.23, 0.53, 0.64, 0.52, 0.42, 0.64, 0.64, 0.0, 0.08, 0.44, 0.13, 0.48, 0.52, 0.81, 0.44, 0.0, 0.26, 0.0, 0.21, 0.03, 0.46, 0.27, 0.71, 0.45, 0.06, 0.28, 0.28, 0.4, 0.65, 0.28, 0.46, 0.61, 0.0, 0.36, 0.0, 0.32, 0.01, 0.22, 0.0, 0.05, 0.0, 0.41, 0.46, 0.42, 0.82, 0.48, 0.4, 0.5, 0.17, 0.62, 0.06, 0.32, 0.0, 0.25, 0.0, 0.42, 0.08, 0.41, 0.27, 0.16, 0.04, 0.36, 0.32, 0.2, 0.0, 0.52, 0.04, 0.66, 0.47, 0.52, 0.78, 0.09, 0.77, 0.08, 0.6, 0.0, 0.31, 0.03, 0.58, 0.47, 0.59, 0.44, 0.23, 0.54, 0.1, 0.18, 0.45, 0.0, 0.53, 0.11, 0.59, 0.17, 0.51, 0.01, 0.19, 0.71, 0.77, 0.3, 0.44, 0.08, 0.14, 0.52, 0.05, 0.37, 0.1, 0.42, 0.23, 0.61, 0.43, 0.22, 0.96, 0.54, 0.4, 0.3, 0.07, 0.39, 0.17, 0.43, 0.38, 0.3, 0.8, 0.83, 0.44, 0.03, 0.11, 0.0, 0.23, 0.0, 0.31, 0.0, 0.38, 0.58, 0.51, 0.01, 0.49, 0.13, 0.26, 0.69, 0.46, 0.41, 0.51, 0.06, 0.51, 0.03, 0.38, 0.0, 0.06, 0.0, 0.34, 0.08, 0.53, 0.42, 0.88, 0.25, 0.75, 0.49, 1.0, 0.34, 0.86, 0.48, 0.18, 0.52, 0.01, 0.32, 0.0, 0.19, 0.0, 0.3, 0.05, 0.44, 0.27, 0.43, 0.11, 0.31, 0.39, 0.03, 0.55, 0.04, 0.52, 0.51, 0.64, 0.57, 0.19, 0.68, 0.13, 0.84, 0.06, 0.31, 0.07, 0.69, 0.26, 0.37, 0.53, 0.67, 0.5, 0.56, 0.14, 0.18, 0.47, 0.01, 0.47, 0.15, 0.61, 0.28, 0.2, 0.02, 0.76, 0.55, 0.31, 0.94, 0.22, 0.57, 0.17, 0.4, 0.07, 0.5, 0.31, 0.7, 0.2, 0.14, 0.3, 0.23, 0.58, 0.07, 0.06, 0.55, 0.15, 0.46, 0.43, 0.64, 0.53, 0.0, 0.18, 0.01, 0.23, 0.02, 0.63, 0.33, 0.79, 0.06, 0.38, 0.07, 0.14, 0.23, 0.68, 0.89, 0.29, 0.06, 0.72, 0.92, 0.24, 0.25, 0.0, 0.46, 0.02, 0.21, 0.01, 0.06, 0.0, 0.05, 0.07, 0.61, 0.17, 0.89, 0.72, 0.66, 0.14, 0.52, 0.07, 0.58, 0.01, 0.26, 0.0, 0.13, 0.0, 0.29, 0.04, 0.46, 0.27, 0.28, 0.23, 0.56, 0.32, 0.25, 0.0, 0.33, 0.05, 0.55, 0.5, 0.58, 0.53, 0.04, 0.27, 0.02, 0.04, 0.37, 0.67, 0.74, 0.35, 0.62, 0.54, 0.26, 0.46, 0.0, 0.47, 0.09, 0.45, 0.15, 0.39, 0.05, 0.44, 0.85, 0.56, 0.11, 0.11, 0.35, 0.42, 0.03, 0.32, 0.12, 0.49, 0.19, 0.25, 0.8, 0.6, 0.09, 0.49, 0.57, 0.36, 0.04, 0.35, 0.28, 0.52, 0.39, 0.5, 0.28, 0.93, 0.47, 0.3, 0.47, 0.08, 0.02, 0.18, 0.01, 0.34, 0.23, 0.55, 0.57, 0.91, 0.1, 0.78, 0.52, 0.34, 0.61, 0.24, 0.75, 0.0, 0.2, 0.02, 0.24, 0.0, 0.18, 0.04, 0.44, 0.59, 0.71, 0.29, 0.52, 0.37, 0.5, 0.11, 0.6, 0.02, 0.48, 0.01, 0.16, 0.04, 0.35, 0.66, 0.47, 0.74, 0.14, 0.62, 0.16, 0.77, 0.79, 0.27, 0.93, 0.69, 0.88, 0.88, 0.85, 0.87, 0.91, 0.92, 0.82, 0.63, 0.75, 0.7, 0.7, 0.38, 0.43, 0.64, 0.55, 0.54, 0.59, 0.45, 0.47, 0.5, 0.58, 0.52, 0.61, 0.57, 0.52, 0.68, 0.44, 0.6, 0.61, 0.58, 0.55, 0.5, 0.61, 0.61, 0.86, 0.86, 0.75, 0.91, 0.96, 0.93, 1.0, 0.87, 0.97, 0.91, 0.95, 0.86, 0.98, 0.93, 0.88, 0.59, 0.87, 0.7, 0.67, 0.85, 0.89, 0.88, 0.91, 0.93, 0.88, 0.99, 0.92, 1.0, 0.79, 0.9, 1.0, 0.94, 1.0, 0.97, 0.96, 0.9, 0.63, 0.68, 0.48, 0.54, 0.8, 0.7, 0.7, 0.95, 0.87, 0.77, 0.84, 0.79, 0.89, 0.95, 0.8, 0.77, 0.51, 0.87, 0.7, 0.52, 0.84, 0.91, 0.51, 0.96, 0.79, 0.92, 0.84, 0.21, 0.89, 0.53, 0.52, 0.89, 0.86, 0.26, 0.91, 0.45, 0.68, 0.84, 0.48, 0.44, 0.51, 0.62, 0.28, 0.59, 0.63, 0.57, 0.15, 0.55, 0.66, 0.1, 0.38, 0.74, 0.65, 0.17, 0.43, 0.66, 0.41, 0.8, 0.75, 0.9, 0.93, 0.52, 0.76, 0.89, 0.87, 0.76, 0.92, 0.91, 0.75, 0.61, 0.96, 0.89, 0.73, 0.97, 0.68, 0.87, 0.55, 0.85, 0.77, 0.69, 0.76, 0.98, 0.83, 0.68, 0.82, 0.74, 0.65, 0.96, 0.93, 0.54, 0.64, 0.28, 0.54, 0.52, 0.16, 0.51, 0.88, 0.6, 0.4, 0.88, 0.95, 0.33, 0.56, 0.73, 0.39, 0.06, 0.61, 0.75, 0.47, 0.19, 0.87, 0.7, 0.97, 0.94, 0.97]
[68.44, 84.75, 88.81, 88.55, 91.74, 92.77, 94.11, 93.29, 93.84, 94.11, 93.55, 93.43, 93.63, 95.07, 92.98, 91.27, 93.01, 92.19, 91.19, 86.62, 84.84, 86.24, 87.42, 86.32, 86.49, 85.36, 90.28, 92.37, 91.78, 93.06, 93.48, 94.13, 93.69, 94.8, 93.71, 93.34, 92.49, 92.78, 91.68, 88.72, 88.52, 86.74, 82.08, 77.6, 75.31, 77.79, 81.21, 77.98, 70.0, 74.43, 80.03, 89.45, 91.62, 91.4, 92.34, 93.14, 94.74, 94.81, 94.65, 94.32, 94.01, 93.38, 92.34, 92.74, 91.79, 90.6, 90.61, 93.61, 93.01, 92.67, 94.0, 93.46, 90.25, 91.12, 94.31, 93.62, 91.75, 92.26, 93.78, 93.08, 91.68, 92.33, 93.35, 90.95, 89.52, 90.32, 90.94, 87.77, 88.13, 87.38, 84.18, 80.16, 75.13, 63.45, 56.8, 50.23, 39.01, 45.42, 42.47, 36.63, 37.5, 31.4, 37.39, 32.88, 30.57, 34.97, 33.68, 47.89, 34.18, 30.54, 47.78, 31.73, 36.65, 33.84, 35.14, 31.4, 38.93, 32.78, 33.8, 33.26, 32.3, 33.11, 29.56, 28.6, 28.59, 27.28, 29.13, 27.56, 28.21, 31.98, 31.79, 36.42, 30.35, 38.18, 34.3, 36.5, 33.51, 33.79, 31.67, 32.66, 37.89, 39.69, 44.4, 48.32, 54.62, 63.69, 74.89, 84.15, 89.38, 89.61, 91.08, 90.24, 90.64, 90.44, 91.14, 90.13, 87.9, 83.97, 85.03, 88.29, 90.29, 88.6, 88.04, 89.37, 91.05, 87.61, 90.32, 90.35, 89.28, 88.76, 89.66, 86.16, 84.56, 89.74, 90.95, 90.47, 89.41, 90.27, 91.21, 89.31, 86.67, 86.34, 87.93, 82.79, 70.04, 54.39, 50.05, 50.94, 53.55, 52.58, 53.33, 52.79, 55.48, 43.06, 41.16, 43.17, 40.1, 45.85, 39.41, 38.15, 44.11, 49.72, 47.2, 56.86, 64.28, 64.3, 68.24, 78.15, 80.61, 86.99, 89.47, 91.74, 92.15, 92.5, 92.51, 91.61, 90.86, 89.31, 91.87, 92.06, 89.18, 83.55, 78.82, 78.75, 77.11, 76.43, 68.49, 72.69, 76.85, 76.64, 77.57, 79.73, 78.55, 79.88, 75.29, 73.93, 77.29, 74.36, 74.74, 69.79, 74.78, 72.62, 74.05, 79.71, 80.55, 79.54, 80.79, 79.4, 82.31, 81.98, 78.03, 78.71, 75.89, 74.99, 75.52, 75.74, 68.69, 72.7, 70.86, 71.6, 66.83, 69.57, 68.6, 69.19, 70.87, 69.84, 67.34, 67.75, 68.04, 66.57, 67.89, 68.93, 68.64, 68.44, 69.75, 75.67, 70.01, 69.93, 73.04, 70.54, 65.73, 68.45, 69.83, 67.03, 67.38, 64.43, 52.47]
[0.74, 0.57, 0.29, 0.31, 0.62, 0.21, 0.0, 0.17, 0.53, 0.24, 0.0, 0.29, 0.47, 0.1, 0.0, 0.56, 0.77, 0.46, 0.21, 0.77, 0.99, 0.21, 0.6, 0.25, 0.73, 0.36, 0.1, 0.4, 0.78, 0.62, 0.02, 0.14, 0.51, 0.36, 0.0, 0.13, 0.3, 0.16, 0.03, 0.64, 0.81, 0.05, 0.27, 0.69, 0.8, 0.04, 0.27, 0.43, 0.95, 0.96, 0.65, 0.11, 0.64, 0.19, 0.58, 0.39, 0.01, 0.17, 0.75, 0.44, 0.0, 0.31, 0.78, 0.32, 0.0, 0.7, 0.17, 0.0, 0.53, 0.82, 0.07, 0.64, 0.56, 0.56, 0.27, 0.0, 0.14, 0.63, 0.09, 0.0, 0.39, 0.68, 0.02, 0.03, 0.32, 0.39, 0.09, 0.27, 0.54, 0.24, 0.67, 0.53, 0.69, 0.77, 0.72, 0.75, 0.79, 0.8, 0.88, 0.96, 0.91, 0.98, 0.96, 1.0, 0.97, 1.0, 1.0, 1.0, 1.0, 0.96, 0.96, 0.92, 0.86, 0.89, 0.89, 0.92, 0.92, 0.9, 0.94, 0.92, 0.82, 0.99, 0.85, 0.99, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 0.99, 0.89, 0.96, 0.86, 0.94, 0.91, 0.89, 0.9, 0.95, 0.76, 0.9, 0.73, 0.88, 0.37, 0.55, 0.86, 0.13, 0.0, 0.55, 0.42, 0.0, 0.28, 0.82, 0.64, 0.25, 0.77, 0.62, 0.08, 0.25, 0.41, 0.68, 0.18, 0.0, 0.31, 0.31, 0.07, 0.05, 0.63, 0.38, 0.14, 0.9, 0.59, 0.47, 0.34, 0.79, 0.59, 0.0, 0.32, 0.49, 0.24, 0.26, 0.65, 0.44, 0.55, 0.64, 0.75, 0.72, 0.35, 0.46, 0.75, 0.87, 0.32, 0.69, 0.6, 0.96, 0.8, 0.62, 0.84, 0.86, 0.9, 0.75, 0.9, 0.84, 0.88, 0.76, 0.34, 0.66, 0.87, 0.87, 0.59, 0.4, 0.74, 0.52, 0.47, 0.49, 0.51, 0.84, 0.75, 0.76, 0.58, 0.93, 0.62, 0.58, 0.63, 0.56, 0.5, 0.81, 0.78, 0.63, 0.77, 0.8, 0.87, 0.72, 0.84, 0.86, 0.91, 0.83, 0.77, 0.76, 0.88, 0.69, 0.9, 0.37, 0.54, 0.52, 0.64, 0.52, 0.91, 0.86, 0.69, 0.53, 0.21, 0.05, 0.54, 0.79, 0.34, 0.55, 0.89, 0.79, 0.49, 0.77, 0.52, 0.72, 0.63, 0.59, 0.68, 0.43, 0.49, 0.66, 0.65, 0.76, 0.79, 0.69, 0.72, 0.76, 0.72, 0.83, 0.93, 0.89, 0.83, 0.91, 0.91, 0.84, 0.95, 0.89, 0.98]
null
Component of an E-cadherin/ catenin adhesion complex composed of at least E-cadherin/CDH1, beta-catenin/CTNNB1 or gamma-catenin/JUP, and potentially alpha-catenin/CTNNA1. Forms a ternary complex composed of ADAM10, CADH1 and EPHA4,
null
null
KLRG1, SPEF1, DLGAP5, AJAP1, RAPGEF2, RAB8B, PIP5K1C, PKP2, TRPV4, CTNNB1, CAV1, DDR1, TBC1D2, CTNNA1, JUP, CTNND1, PSEN1, LIMA1, CDH1, JUP, ADAM10, CADH1 , EPHA4,
null
null
null
null
Homodimer
null
79.91949
0.474025
72.817491
0.590627
2,439
P12830
Q9NQW6
null
degron_data
CDH1
MGPWSRSLSALLLLLQVSSWLCQEPEPCHPGFDAESYTFTVPRRHLERGRVLGRVNFEDCTGRQRTAYFSLDTRFKVGTDGVITVKRPLRFHNPQIHFLVYAWDSTYRKFSTKVTLNTVGHHHRPPPHQASVSGIQAELLTFPNSSPGLRRQKRDWVIPPISCPENEKGPFPKNLVQIKSNKDKEGKVFYSITGQGADTPPVGVFIIERETGWLKVTEPLDRERIATYTLFSHAVSSNGNAVEDPMEILITVTDQNDNKPEFTQEVFKGSVMEGALPGTSVMEVTATDADDDVNTYNAAIAYTILSQDPELPDKNMFTINRNTGVISVVTTGLDRESFPTYTLVVQAADLQGEGLSTTATAVITVTDTNDNPPIFNPTTYKGQVPENEANVVITTLKVTDADAPNTPAWEAVYTILNDDGGQFVVTTNPVNNDGILKTAKGLDFEAKQQYILHVAVTNVVPFEVSLTTSTATVTVDVLDVNEAPIFVPPEKRVEVSEDFGVGQEITSYTAQEPDTFMEQKITYRIWRDTANWLEINPDTGAISTRAELDREDFEHVKNSTYTALIIATDNGSPVATGTGTLLLILSDVNDNAPIPEPRTIFFCERNPKPQVINIIDADLPPNTSPFTAELTHGASANWTIQYNDPTQESIILKPKMALEVGDYKINLKLMDNQNKDQVTTLEVSVCDCEGAAGVCRKAQPVEAGLQIPAILGILGGILALLILILLLLLFLRRRAVVKEPLLPPEDDTRDNVYYYDEEGGGEEDQDFDLSQLHRGLDARPEVTRNDVAPTLMSVPRYLPRPANPDEIGNFIDENLKAADTDPTAPPYDSLLVFDYEGSGSEAASLSSLNSSESDKDQDYDYLNEWGNRFKKLADMYGGGEDD
Homo sapiens
Cell junction, adherens junction, Cell membrane, Endosome, Golgi apparatus, trans-Golgi network, Cytoplasm, Cell junction, desmosome
Tissue enhanced (parathyroid)
{'Ciliated cells': '119.1', 'Basal respiratory cells': '71.1', 'Club cells': '97.3', 'Ionocytes': '81.0', 'Mucus glandular cells': '155.0', 'Serous glandular cells': '67.8', 'Gastric mucus-secreting cells': '133.2', 'Proximal enterocytes': '140.9', 'Paneth cells': '125.1', 'Distal enterocytes': '307.5', 'Intestinal goblet cells': '173.5', 'Exocrine glandular cells': '-0.605', 'Basal prostatic cells': '68.3', 'Prostatic glandular cells': '186.7', 'Breast glandular cells': '0.773', 'Breast myoepithelial cells': '0.700', 'Glandular and luminal cells': '313.0', 'Secretory cells': '82.3', 'Basal keratinocytes': '102.5', 'Suprabasal keratinocytes': '162.6', 'Basal squamous epithelial cells': '51.0', 'Squamous epithelial cells': '106.9', 'Alveolar cells type 1': '0.437', 'Alveolar cells type 2': '0.706', 'Salivary duct cells': '95.9', 'Ductal cells': '0.541', 'Hepatocytes': '0.600', 'Cholangiocytes': '129.7', 'Proximal tubular cells': '0.042', 'Distal tubular cells': '0.0', 'Collecting duct cells': '143.9', 'Mesothelial cells': '0.799', 'Sertoli cells': '0.252', 'Granulosa cells': '12.9', 'Enteroendocrine cells': '92.4', 'Pancreatic endocrine cells': '78.1', 'Leydig cells': '0.264', 'Excitatory neurons': '0.7', 'Inhibitory neurons': '1.3', 'Cone photoreceptor cells': '0.0', 'Rod photoreceptor cells': '0.0', 'Bipolar cells': '0.2', 'Horizontal cells': '0.6', 'Astrocytes': '0.6', 'Oligodendrocyte precursor cells': '0.5', 'Oligodendrocytes': '29.9', 'Microglial cells': '0.9', 'Muller glia cells': '0.1', 'Schwann cells': '0.131', 'Spermatogonia': '0.392', 'Spermatocytes': '0.193', 'Early spermatids': '-0.217', 'Late spermatids': '-0.290', 'Oocytes': '16.9', 'Cytotrophoblasts': '119.2', 'Syncytiotrophoblasts': '45.0', 'Extravillous trophoblasts': '24.9', 'Endothelial cells': '6.1', 'Lymphatic endothelial cells': '0.4', 'Cardiomyocytes': '0.135', 'Skeletal myocytes': '0.107', 'Smooth muscle cells': '5.8', 'Adipocytes': '2.1', 'Melanocytes': '0.335', 'Fibroblasts': '6.5', 'Peritubular cells': '0.210', 'Endometrial stromal cells': '27.7', 'Ovarian stromal cells': '0.7', 'Undifferentiated cells': '101.6', 'T-cells': '2.9', 'B-cells': '4.4', 'Plasma cells': '6.1', 'Nk-cells': '0.0', 'Granulocytes': '8.4', 'Monocytes': '0.0', 'Macrophages': '6.0', 'Hofbauer cells': '4.3', 'Kupffer cells': '1.0', 'Dendritic cells': '5.9', 'Langerhans cells': '0.304', 'Erythroid cells': '0.036', 'Adipocytes (Subcutaneous)': '-0.081', 'Adipocytes (Visceral)': '-0.209', 'Breast glandular cells (progenitors)': '0.538', 'Adipocytes (Breast)': '-0.689', 'Colon enterocytes': '0.790', 'Colon enteroendocrine cells': '0.112', 'Enteric glia cells': '-0.048', 'Mitotic cells (Colon)': '0.299', 'Mitotic cells (Heart)': '0.120', 'Podocytes': '-0.118', 'Ascending Loop of Henle cells': '0.475', 'Intercalated cells': '0.212', 'Cholangiocyte': '0.090', 'NK-cells (Liver)': '-0.005', 'Respiratory ciliated cells': '-0.012', 'Mitotic cells (Lung)': '0.071', 'NK-cells (Lung)': '-0.266', 'B-cells (Lung)': '-0.296', 'Alpha cells': '0.270', 'Beta cells': '0.152', 'Prostate glandular cells': '0.764', 'Prostate basal glandular cells': '0.540', 'Urothelial cells': '0.205', 'Keratinocyte (other)': '0.510', 'Keratinocyte (granular)': '0.055', 'Hair cortex cells': '0.080', 'Inner root sheath cells': '0.131', 'Outer root sheath cells': '0.175', 'Sebaceous gland cells': '0.156', 'Eccrine sweat gland cells': '-0.207', 'Adipocytes (Skin)': '-0.244', 'Mitotic cells (Skin)': '0.442', 'Parietal cells': '0.654', 'Chief cells': '0.649', 'Gastric mucous cells': '0.781', 'Gastric enteroendocrine cells': '0.590', 'Mitotic cells (Stomach)': '0.445', 'Parafollicular cells': '0.173', 'Thyroid glandular cells': '0.865', 'Mitotic cells (Thyroid)': '-0.081', 'Adrenal cortex cells': '0.051', 'Adrenal medulla cells': '0.087', 'Mitotic cells (Adrenal gland)': '0.072', 'Minor salivary glandular cells': '0.371', 'Minor salivary gland ductal cells': '-0.142', 'Minor salivary gland basal cells': '0.582', 'Mitotic cells (Minor salivary gland)': '0.567', 'Adipocytes (Minor salivary gland)': '0.050', 'Somatotropes': '0.121', 'Lactotropes': '0.322', 'Gonadotropes': '0.330', 'Corticotropes': '0.180', 'Thyrotropes': '0.496', 'Undifferentiated cells (Pituitary gland)': '-0.108', 'Mitotic cells (Spleen)': '-0.228', 'Platelets': '-0.050', 'Erythrocytes': '-0.158', 'Hematopoietic stem cells': '-0.211', 'B-cells (Spleen)': '0.266', 'NK-cells (Spleen)': '0.309', 'Amygdala excitatory': '1.0', 'Cerebellar inhibitory': '0.9', 'Cge interneuron': '0.7', 'Deep-layer corticothalamic and 6b': '1.5', 'Deep-layer intratelencephalic': '0.7', 'Deep-layer near-projecting': '0.7', 'Eccentric medium spiny neuron': '0.6', 'Hippocampal ca1-3': '1.9', 'Hippocampal ca4': '1.2', 'Hippocampal dentate gyrus': '1.1', 'Lamp5-lhx6 and chandelier': '0.5', 'Lower rhombic lip': '0.8', 'Mammillary body': '0.6', 'Medium spiny neuron': '0.7', 'Mge interneuron': '1.7', 'Midbrain-derived inhibitory': '0.7', 'Miscellaneous': '0.9', 'Splatter': '3.8', 'Thalamic excitatory': '0.5', 'Upper rhombic lip': '0.8', 'Upper-layer intratelencephalic': '0.6', 'Astrocyte': '4.4', 'Bergmann glia': '0.2', 'Central nervous system macrophage': '0.6', 'Choroid plexus epithelial cell': '52.1', 'Committed oligodendrocyte precursor': '41.5', 'Ependymal cell': '4.8', 'Oligodendrocyte': '53.1', 'Oligodendrocyte precursor cell': '2.4', 'Endothelial cell': '0.7', 'Pericyte': '0.3', 'Vascular associated smooth muscle cell': '0.0', 'Fibroblast': '17.4', 'Leukocyte': '1.1', 'Basophil': '0.0', 'Eosinophil': '0.0', 'Neutrophil': '0.0', 'Classical monocyte': '0.0', 'Non-classical monocyte': '0.0', 'Intermediate monocyte': '0.0', 'T-reg': '2.3', 'GdT-cell': '0.0', 'MAIT T-cell': '0.0', 'Memory CD4 T-cell': '0.0', 'Naive CD4 T-cell': '0.1', 'Memory CD8 T-cell': '0.2', 'Naive CD8 T-cell': '0.3', 'Memory B-cell': '0.0', 'Naive B-cell': '0.1', 'Plasmacytoid DC': '46.6', 'Myeloid DC': '8.5', 'NK-cell': '0.1', 'Total PBMC': '0.7', 'Vd2 gdTCR': '0.0', 'Memory CD4 T-cell Th1\\/Th17': '0.1', 'Memory CD4 T-cell Th17': '0.2', 'Memory CD4 T-cell Th2': '2.9', 'Non-Vd2 gdTCR': '0.1', 'Memory CD4 T-cell Th1': '0.3', 'Memory CD4 T-cell TFH': '0.5', 'Terminal effector memory CD4 T-cell': '0.0', 'Central memory CD8 T-cell': '4.8', 'Effector memory CD8 T-cell': '0.0', 'Terminal effector memory CD8 T-cell': '0.6', 'Non-switched memory B-cell': '0.0', 'Plasmablast': '3.3', 'Switched memory B-cell': '0.0', 'Exhausted memory B-cell': '0.7', 'Progenitor cell': '2.3', 'Memory T-reg': '1.3', 'Naive CD4 T-cell activated': '0.3', 'Naive CD8 T-cell activated': '0.6', 'Naive T-reg': '0.1'}
1O6S, 2O72, 2OMT, 2OMU, 2OMV, 2OMX, 2OMY, 2OMZ, 3FF7, 3FF8, 3L6X, 3L6Y, 4ZT1, 4ZTE, 6CXY, 6OLE, 6OLF, 6OLG, 6VEL, 7STZ, 8H62
{'Adipose Tissue': 1.2125261088039867, 'Adrenal Gland': 0.1914223992248062, 'Bladder': 39.2033519047619, 'Blood': 1.340954264800861, 'Blood Vessel': 0.3121561692883895, 'Brain': 0.8550442199091597, 'Breast': 38.54918344226579, 'Cervix Uteri': 23.539115789473684, 'Colon': 43.41292142490372, 'Esophagus': 53.97513367404844, 'Fallopian Tube': 14.900277777777776, 'Heart': 0.119140469221835, 'Kidney': 25.040449438202245, 'Liver': 26.60802654867257, 'Lung': 35.447986366782004, 'Muscle': 0.1378936151930261, 'Nerve': 17.518468982229404, 'Ovary': 3.6515122222222223, 'Pancreas': 56.89676829268293, 'Pituitary': 24.68741660777385, 'Prostate': 61.279967346938776, 'Salivary Gland': 92.01685185185184, 'Skin': 79.77571720232172, 'Small Intestine': 71.7519320855615, 'Spleen': 10.061029045643156, 'Stomach': 58.07813805013927, 'Testis': 0.8144204986149585, 'Thyroid': 135.176797856049, 'Uterus': 1.442593943661972, 'Vagina': 86.52345512820513}
ANLN
MDPFTEKLLERTRARRENLQRKMAERPTAAPRSMTHAKRARQPLSEASNQQPLSGGEEKSCTKPSPSKKRCSDNTEVEVSNLENKQPVESTSAKSCSPSPVSPQVQPQAADTISDSVAVPASLLGMRRGLNSRLEATAASSVKTRMQKLAEQRRRWDNDDMTDDIPESSLFSPMPSEEKAASPPRPLLSNASATPVGRRGRLANLAATICSWEDDVNHSFAKQNSVQEQPGTACLSKFSSASGASARINSSSVKQEATFCSQRDGDASLNKALSSSADDASLVNASISSSVKATSPVKSTTSITDAKSCEGQNPELLPKTPISPLKTGVSKPIVKSTLSQTVPSKGELSREICLQSQSKDKSTTPGGTGIKPFLERFGERCQEHSKESPARSTPHRTPIITPNTKAIQERLFKQDTSSSTTHLAQQLKQERQKELACLRGRFDKGNIWSAEKGGNSKSKQLETKQETHCQSTPLKKHQGVSKTQSLPVTEKVTENQIPAKNSSTEPKGFTECEMTKSSPLKITLFLEEDKSLKVTSDPKVEQKIEVIREIEMSVDDDDINSSKVINDLFSDVLEEGELDMEKSQEEMDQALAESSEEQEDALNISSMSLLAPLAQTVGVVSPESLVSTPRLELKDTSRSDESPKPGKFQRTRVPRAESGDSLGSEDRDLLYSIDAYRSQRFKETERPSIKQVIVRKEDVTSKLDEKNNAFPCQVNIKQKMQELNNEINMQQTVIYQASQALNCCVDEEHGKGSLEEAEAERLLLIATGKRTLLIDELNKLKNEGPQRKNKASPQSEFMPSKGSVTLSEIRLPLKADFVCSTVQKPDAANYYYLIILKAGAENMVATPLASTSNSLNGDALTFTTTFTLQDVSNDFEINIEVYSLVQKKDPSGLDKKKKTSKSKAITPKRLLTSITTKSNIHSSVMASPGGLSAVRTSNFALVGSYTLSLSSVGNTKFVLDKVPFLSSLEGHIYLKIKCQVNSSVEERGFLTIFEDVSGFGAWHRRWCVLSGNCISYWTYPDDEKRKNPIGRINLANCTSRQIEPANREFCARRNTFELITVRPQREDDRETLVSQCRDTLCVTKNWLSADTKEERDLWMQKLNQVLVDIRLWQPDACYKPIGKP
Homo sapiens
Nucleus, Cytoplasm, cytoskeleton, Cytoplasm, cell cortex, Cell projection, bleb
Tissue enriched (brain)
{'Ciliated cells': '11.2', 'Basal respiratory cells': '7.8', 'Club cells': '3.6', 'Ionocytes': '7.4', 'Mucus glandular cells': '3.2', 'Serous glandular cells': '0.2', 'Gastric mucus-secreting cells': '11.8', 'Proximal enterocytes': '0.1', 'Paneth cells': '1.4', 'Distal enterocytes': '0.6', 'Intestinal goblet cells': '3.0', 'Exocrine glandular cells': '-0.326', 'Basal prostatic cells': '0.2', 'Prostatic glandular cells': '0.0', 'Breast glandular cells': '0.155', 'Breast myoepithelial cells': '0.317', 'Glandular and luminal cells': '9.7', 'Secretory cells': '0.6', 'Basal keratinocytes': '15.9', 'Suprabasal keratinocytes': '9.3', 'Basal squamous epithelial cells': '12.4', 'Squamous epithelial cells': '24.5', 'Alveolar cells type 1': '-0.251', 'Alveolar cells type 2': '0.121', 'Salivary duct cells': '4.5', 'Ductal cells': '0.529', 'Hepatocytes': '0.257', 'Cholangiocytes': '0.0', 'Proximal tubular cells': '0.176', 'Distal tubular cells': '0.0', 'Collecting duct cells': '0.0', 'Mesothelial cells': '0.361', 'Sertoli cells': '-0.143', 'Granulosa cells': '5.2', 'Enteroendocrine cells': '0.3', 'Pancreatic endocrine cells': '6.8', 'Leydig cells': '-0.131', 'Excitatory neurons': '3.3', 'Inhibitory neurons': '5.4', 'Cone photoreceptor cells': '0.0', 'Rod photoreceptor cells': '0.0', 'Bipolar cells': '0.2', 'Horizontal cells': '0.0', 'Astrocytes': '2.2', 'Oligodendrocyte precursor cells': '1.4', 'Oligodendrocytes': '410.7', 'Microglial cells': '0.0', 'Muller glia cells': '0.0', 'Schwann cells': '0.126', 'Spermatogonia': '0.408', 'Spermatocytes': '0.800', 'Early spermatids': '0.518', 'Late spermatids': '0.182', 'Oocytes': '20.6', 'Cytotrophoblasts': '13.9', 'Syncytiotrophoblasts': '3.3', 'Extravillous trophoblasts': '23.4', 'Endothelial cells': '1.2', 'Lymphatic endothelial cells': '0.1', 'Cardiomyocytes': '0.422', 'Skeletal myocytes': '0.113', 'Smooth muscle cells': '2.6', 'Adipocytes': '0.3', 'Melanocytes': '0.473', 'Fibroblasts': '3.5', 'Peritubular cells': '-0.164', 'Endometrial stromal cells': '2.3', 'Ovarian stromal cells': '1.4', 'Undifferentiated cells': '13.6', 'T-cells': '1.3', 'B-cells': '0.7', 'Plasma cells': '9.2', 'Nk-cells': '1.2', 'Granulocytes': '0.0', 'Monocytes': '0.2', 'Macrophages': '3.8', 'Hofbauer cells': '7.6', 'Kupffer cells': '2.5', 'Dendritic cells': '0.8', 'Langerhans cells': '0.269', 'Erythroid cells': '0.139', 'Adipocytes (Subcutaneous)': '-0.188', 'Adipocytes (Visceral)': '-0.214', 'Breast glandular cells (progenitors)': '0.239', 'Adipocytes (Breast)': '-0.125', 'Colon enterocytes': '0.130', 'Colon enteroendocrine cells': '-0.010', 'Enteric glia cells': '-0.233', 'Mitotic cells (Colon)': '0.405', 'Mitotic cells (Heart)': '0.756', 'Podocytes': '-0.244', 'Ascending Loop of Henle cells': '0.393', 'Intercalated cells': '-0.232', 'Cholangiocyte': '0.295', 'NK-cells (Liver)': '-0.113', 'Respiratory ciliated cells': '0.021', 'Mitotic cells (Lung)': '0.938', 'NK-cells (Lung)': '-0.132', 'B-cells (Lung)': '-0.010', 'Alpha cells': '0.222', 'Beta cells': '0.058', 'Prostate glandular cells': '-0.209', 'Prostate basal glandular cells': '0.090', 'Urothelial cells': '0.113', 'Keratinocyte (other)': '0.528', 'Keratinocyte (granular)': '0.032', 'Hair cortex cells': '-0.104', 'Inner root sheath cells': '0.000', 'Outer root sheath cells': '0.017', 'Sebaceous gland cells': '-0.060', 'Eccrine sweat gland cells': '-0.113', 'Adipocytes (Skin)': '-0.278', 'Mitotic cells (Skin)': '0.821', 'Parietal cells': '-0.274', 'Chief cells': '-0.278', 'Gastric mucous cells': '0.198', 'Gastric enteroendocrine cells': '-0.145', 'Mitotic cells (Stomach)': '0.787', 'Parafollicular cells': '0.014', 'Thyroid glandular cells': '-0.067', 'Mitotic cells (Thyroid)': '0.731', 'Adrenal cortex cells': '0.476', 'Adrenal medulla cells': '0.115', 'Mitotic cells (Adrenal gland)': '0.930', 'Minor salivary glandular cells': '0.166', 'Minor salivary gland ductal cells': '-0.301', 'Minor salivary gland basal cells': '0.711', 'Mitotic cells (Minor salivary gland)': '0.951', 'Adipocytes (Minor salivary gland)': '0.176', 'Somatotropes': '0.057', 'Lactotropes': '-0.328', 'Gonadotropes': '-0.093', 'Corticotropes': '-0.284', 'Thyrotropes': '-0.205', 'Undifferentiated cells (Pituitary gland)': '0.236', 'Mitotic cells (Spleen)': '0.915', 'Platelets': '0.183', 'Erythrocytes': '0.378', 'Hematopoietic stem cells': '0.510', 'B-cells (Spleen)': '-0.272', 'NK-cells (Spleen)': '-0.214', 'Amygdala excitatory': '2.5', 'Cerebellar inhibitory': '4.7', 'Cge interneuron': '10.3', 'Deep-layer corticothalamic and 6b': '6.5', 'Deep-layer intratelencephalic': '5.1', 'Deep-layer near-projecting': '1.8', 'Eccentric medium spiny neuron': '1.9', 'Hippocampal ca1-3': '6.5', 'Hippocampal ca4': '2.0', 'Hippocampal dentate gyrus': '1.8', 'Lamp5-lhx6 and chandelier': '4.6', 'Lower rhombic lip': '4.4', 'Mammillary body': '2.3', 'Medium spiny neuron': '1.9', 'Mge interneuron': '9.7', 'Midbrain-derived inhibitory': '7.3', 'Miscellaneous': '4.0', 'Splatter': '7.1', 'Thalamic excitatory': '3.3', 'Upper rhombic lip': '2.4', 'Upper-layer intratelencephalic': '1.8', 'Astrocyte': '14.1', 'Bergmann glia': '2.4', 'Central nervous system macrophage': '9.5', 'Choroid plexus epithelial cell': '16.0', 'Committed oligodendrocyte precursor': '123.2', 'Ependymal cell': '4.7', 'Oligodendrocyte': '798.3', 'Oligodendrocyte precursor cell': '9.9', 'Endothelial cell': '6.7', 'Pericyte': '5.9', 'Vascular associated smooth muscle cell': '5.6', 'Fibroblast': '4.8', 'Leukocyte': '11.2', 'Basophil': '0.6', 'Eosinophil': '0.0', 'Neutrophil': '0.8', 'Classical monocyte': '0.4', 'Non-classical monocyte': '0.2', 'Intermediate monocyte': '0.2', 'T-reg': '1.3', 'GdT-cell': '0.0', 'MAIT T-cell': '0.0', 'Memory CD4 T-cell': '0.1', 'Naive CD4 T-cell': '0.1', 'Memory CD8 T-cell': '0.0', 'Naive CD8 T-cell': '0.1', 'Memory B-cell': '0.0', 'Naive B-cell': '0.0', 'Plasmacytoid DC': '0.9', 'Myeloid DC': '0.5', 'NK-cell': '0.4', 'Total PBMC': '1.2', 'Vd2 gdTCR': '0.0', 'Memory CD4 T-cell Th1\\/Th17': '0.0', 'Memory CD4 T-cell Th17': '0.3', 'Memory CD4 T-cell Th2': '0.3', 'Non-Vd2 gdTCR': '0.0', 'Memory CD4 T-cell Th1': '0.3', 'Memory CD4 T-cell TFH': '0.1', 'Terminal effector memory CD4 T-cell': '0.0', 'Central memory CD8 T-cell': '0.0', 'Effector memory CD8 T-cell': '0.7', 'Terminal effector memory CD8 T-cell': '0.0', 'Non-switched memory B-cell': '0.1', 'Plasmablast': '11.1', 'Switched memory B-cell': '1.0', 'Exhausted memory B-cell': '1.3', 'Progenitor cell': '2.0', 'Memory T-reg': '1.1', 'Naive CD4 T-cell activated': '0.0', 'Naive CD8 T-cell activated': '0.0', 'Naive T-reg': '0.1'}
2Y7B, 4XH3, 4XOI
{'Adipose Tissue': 1.2490008720930232, 'Adrenal Gland': 1.1037485271317828, 'Bladder': 1.2984714285714287, 'Blood': 4.4478064047362755, 'Blood Vessel': 1.8197702621722849, 'Brain': 40.529177214231645, 'Breast': 0.8064088235294118, 'Cervix Uteri': 1.8092210526315793, 'Colon': 2.4162376123234917, 'Esophagus': 7.099100000000001, 'Fallopian Tube': 0.8456444444444444, 'Heart': 0.4951860720092915, 'Kidney': 0.5154664044943821, 'Liver': 0.4525706637168141, 'Lung': 2.349706574394464, 'Muscle': 0.2143461768368617, 'Nerve': 0.8463764135702747, 'Ovary': 1.817663888888889, 'Pancreas': 0.1969880548780488, 'Pituitary': 0.5337548409893993, 'Prostate': 1.0851015918367348, 'Salivary Gland': 2.6732617283950617, 'Skin': 31.7571184079602, 'Small Intestine': 2.7859898395721925, 'Spleen': 1.9446248962655603, 'Stomach': 2.463101894150418, 'Testis': 13.302301939058172, 'Thyroid': 0.6181701225114855, 'Uterus': 0.7514246478873239, 'Vagina': 6.170469871794872}
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null
Component of an E-cadherin/ catenin adhesion complex composed of at least E-cadherin/CDH1, beta-catenin/CTNNB1 or gamma-catenin/JUP, and potentially alpha-catenin/CTNNA1. Forms a ternary complex composed of ADAM10, CADH1 and EPHA4,
null
null
KLRG1, SPEF1, DLGAP5, AJAP1, RAPGEF2, RAB8B, PIP5K1C, PKP2, TRPV4, CTNNB1, CAV1, DDR1, TBC1D2, CTNNA1, JUP, CTNND1, PSEN1, LIMA1, CDH1, JUP, ADAM10, CADH1 , EPHA4,
null
null
null
null
Homodimer
null
79.91949
0.474025
58.972367
0.710418
393
P12830
Q9NYD6
null
degron_data
CDH1
MGPWSRSLSALLLLLQVSSWLCQEPEPCHPGFDAESYTFTVPRRHLERGRVLGRVNFEDCTGRQRTAYFSLDTRFKVGTDGVITVKRPLRFHNPQIHFLVYAWDSTYRKFSTKVTLNTVGHHHRPPPHQASVSGIQAELLTFPNSSPGLRRQKRDWVIPPISCPENEKGPFPKNLVQIKSNKDKEGKVFYSITGQGADTPPVGVFIIERETGWLKVTEPLDRERIATYTLFSHAVSSNGNAVEDPMEILITVTDQNDNKPEFTQEVFKGSVMEGALPGTSVMEVTATDADDDVNTYNAAIAYTILSQDPELPDKNMFTINRNTGVISVVTTGLDRESFPTYTLVVQAADLQGEGLSTTATAVITVTDTNDNPPIFNPTTYKGQVPENEANVVITTLKVTDADAPNTPAWEAVYTILNDDGGQFVVTTNPVNNDGILKTAKGLDFEAKQQYILHVAVTNVVPFEVSLTTSTATVTVDVLDVNEAPIFVPPEKRVEVSEDFGVGQEITSYTAQEPDTFMEQKITYRIWRDTANWLEINPDTGAISTRAELDREDFEHVKNSTYTALIIATDNGSPVATGTGTLLLILSDVNDNAPIPEPRTIFFCERNPKPQVINIIDADLPPNTSPFTAELTHGASANWTIQYNDPTQESIILKPKMALEVGDYKINLKLMDNQNKDQVTTLEVSVCDCEGAAGVCRKAQPVEAGLQIPAILGILGGILALLILILLLLLFLRRRAVVKEPLLPPEDDTRDNVYYYDEEGGGEEDQDFDLSQLHRGLDARPEVTRNDVAPTLMSVPRYLPRPANPDEIGNFIDENLKAADTDPTAPPYDSLLVFDYEGSGSEAASLSSLNSSESDKDQDYDYLNEWGNRFKKLADMYGGGEDD
Homo sapiens
Cell junction, adherens junction, Cell membrane, Endosome, Golgi apparatus, trans-Golgi network, Cytoplasm, Cell junction, desmosome
Tissue enhanced (parathyroid)
{'Ciliated cells': '119.1', 'Basal respiratory cells': '71.1', 'Club cells': '97.3', 'Ionocytes': '81.0', 'Mucus glandular cells': '155.0', 'Serous glandular cells': '67.8', 'Gastric mucus-secreting cells': '133.2', 'Proximal enterocytes': '140.9', 'Paneth cells': '125.1', 'Distal enterocytes': '307.5', 'Intestinal goblet cells': '173.5', 'Exocrine glandular cells': '-0.605', 'Basal prostatic cells': '68.3', 'Prostatic glandular cells': '186.7', 'Breast glandular cells': '0.773', 'Breast myoepithelial cells': '0.700', 'Glandular and luminal cells': '313.0', 'Secretory cells': '82.3', 'Basal keratinocytes': '102.5', 'Suprabasal keratinocytes': '162.6', 'Basal squamous epithelial cells': '51.0', 'Squamous epithelial cells': '106.9', 'Alveolar cells type 1': '0.437', 'Alveolar cells type 2': '0.706', 'Salivary duct cells': '95.9', 'Ductal cells': '0.541', 'Hepatocytes': '0.600', 'Cholangiocytes': '129.7', 'Proximal tubular cells': '0.042', 'Distal tubular cells': '0.0', 'Collecting duct cells': '143.9', 'Mesothelial cells': '0.799', 'Sertoli cells': '0.252', 'Granulosa cells': '12.9', 'Enteroendocrine cells': '92.4', 'Pancreatic endocrine cells': '78.1', 'Leydig cells': '0.264', 'Excitatory neurons': '0.7', 'Inhibitory neurons': '1.3', 'Cone photoreceptor cells': '0.0', 'Rod photoreceptor cells': '0.0', 'Bipolar cells': '0.2', 'Horizontal cells': '0.6', 'Astrocytes': '0.6', 'Oligodendrocyte precursor cells': '0.5', 'Oligodendrocytes': '29.9', 'Microglial cells': '0.9', 'Muller glia cells': '0.1', 'Schwann cells': '0.131', 'Spermatogonia': '0.392', 'Spermatocytes': '0.193', 'Early spermatids': '-0.217', 'Late spermatids': '-0.290', 'Oocytes': '16.9', 'Cytotrophoblasts': '119.2', 'Syncytiotrophoblasts': '45.0', 'Extravillous trophoblasts': '24.9', 'Endothelial cells': '6.1', 'Lymphatic endothelial cells': '0.4', 'Cardiomyocytes': '0.135', 'Skeletal myocytes': '0.107', 'Smooth muscle cells': '5.8', 'Adipocytes': '2.1', 'Melanocytes': '0.335', 'Fibroblasts': '6.5', 'Peritubular cells': '0.210', 'Endometrial stromal cells': '27.7', 'Ovarian stromal cells': '0.7', 'Undifferentiated cells': '101.6', 'T-cells': '2.9', 'B-cells': '4.4', 'Plasma cells': '6.1', 'Nk-cells': '0.0', 'Granulocytes': '8.4', 'Monocytes': '0.0', 'Macrophages': '6.0', 'Hofbauer cells': '4.3', 'Kupffer cells': '1.0', 'Dendritic cells': '5.9', 'Langerhans cells': '0.304', 'Erythroid cells': '0.036', 'Adipocytes (Subcutaneous)': '-0.081', 'Adipocytes (Visceral)': '-0.209', 'Breast glandular cells (progenitors)': '0.538', 'Adipocytes (Breast)': '-0.689', 'Colon enterocytes': '0.790', 'Colon enteroendocrine cells': '0.112', 'Enteric glia cells': '-0.048', 'Mitotic cells (Colon)': '0.299', 'Mitotic cells (Heart)': '0.120', 'Podocytes': '-0.118', 'Ascending Loop of Henle cells': '0.475', 'Intercalated cells': '0.212', 'Cholangiocyte': '0.090', 'NK-cells (Liver)': '-0.005', 'Respiratory ciliated cells': '-0.012', 'Mitotic cells (Lung)': '0.071', 'NK-cells (Lung)': '-0.266', 'B-cells (Lung)': '-0.296', 'Alpha cells': '0.270', 'Beta cells': '0.152', 'Prostate glandular cells': '0.764', 'Prostate basal glandular cells': '0.540', 'Urothelial cells': '0.205', 'Keratinocyte (other)': '0.510', 'Keratinocyte (granular)': '0.055', 'Hair cortex cells': '0.080', 'Inner root sheath cells': '0.131', 'Outer root sheath cells': '0.175', 'Sebaceous gland cells': '0.156', 'Eccrine sweat gland cells': '-0.207', 'Adipocytes (Skin)': '-0.244', 'Mitotic cells (Skin)': '0.442', 'Parietal cells': '0.654', 'Chief cells': '0.649', 'Gastric mucous cells': '0.781', 'Gastric enteroendocrine cells': '0.590', 'Mitotic cells (Stomach)': '0.445', 'Parafollicular cells': '0.173', 'Thyroid glandular cells': '0.865', 'Mitotic cells (Thyroid)': '-0.081', 'Adrenal cortex cells': '0.051', 'Adrenal medulla cells': '0.087', 'Mitotic cells (Adrenal gland)': '0.072', 'Minor salivary glandular cells': '0.371', 'Minor salivary gland ductal cells': '-0.142', 'Minor salivary gland basal cells': '0.582', 'Mitotic cells (Minor salivary gland)': '0.567', 'Adipocytes (Minor salivary gland)': '0.050', 'Somatotropes': '0.121', 'Lactotropes': '0.322', 'Gonadotropes': '0.330', 'Corticotropes': '0.180', 'Thyrotropes': '0.496', 'Undifferentiated cells (Pituitary gland)': '-0.108', 'Mitotic cells (Spleen)': '-0.228', 'Platelets': '-0.050', 'Erythrocytes': '-0.158', 'Hematopoietic stem cells': '-0.211', 'B-cells (Spleen)': '0.266', 'NK-cells (Spleen)': '0.309', 'Amygdala excitatory': '1.0', 'Cerebellar inhibitory': '0.9', 'Cge interneuron': '0.7', 'Deep-layer corticothalamic and 6b': '1.5', 'Deep-layer intratelencephalic': '0.7', 'Deep-layer near-projecting': '0.7', 'Eccentric medium spiny neuron': '0.6', 'Hippocampal ca1-3': '1.9', 'Hippocampal ca4': '1.2', 'Hippocampal dentate gyrus': '1.1', 'Lamp5-lhx6 and chandelier': '0.5', 'Lower rhombic lip': '0.8', 'Mammillary body': '0.6', 'Medium spiny neuron': '0.7', 'Mge interneuron': '1.7', 'Midbrain-derived inhibitory': '0.7', 'Miscellaneous': '0.9', 'Splatter': '3.8', 'Thalamic excitatory': '0.5', 'Upper rhombic lip': '0.8', 'Upper-layer intratelencephalic': '0.6', 'Astrocyte': '4.4', 'Bergmann glia': '0.2', 'Central nervous system macrophage': '0.6', 'Choroid plexus epithelial cell': '52.1', 'Committed oligodendrocyte precursor': '41.5', 'Ependymal cell': '4.8', 'Oligodendrocyte': '53.1', 'Oligodendrocyte precursor cell': '2.4', 'Endothelial cell': '0.7', 'Pericyte': '0.3', 'Vascular associated smooth muscle cell': '0.0', 'Fibroblast': '17.4', 'Leukocyte': '1.1', 'Basophil': '0.0', 'Eosinophil': '0.0', 'Neutrophil': '0.0', 'Classical monocyte': '0.0', 'Non-classical monocyte': '0.0', 'Intermediate monocyte': '0.0', 'T-reg': '2.3', 'GdT-cell': '0.0', 'MAIT T-cell': '0.0', 'Memory CD4 T-cell': '0.0', 'Naive CD4 T-cell': '0.1', 'Memory CD8 T-cell': '0.2', 'Naive CD8 T-cell': '0.3', 'Memory B-cell': '0.0', 'Naive B-cell': '0.1', 'Plasmacytoid DC': '46.6', 'Myeloid DC': '8.5', 'NK-cell': '0.1', 'Total PBMC': '0.7', 'Vd2 gdTCR': '0.0', 'Memory CD4 T-cell Th1\\/Th17': '0.1', 'Memory CD4 T-cell Th17': '0.2', 'Memory CD4 T-cell Th2': '2.9', 'Non-Vd2 gdTCR': '0.1', 'Memory CD4 T-cell Th1': '0.3', 'Memory CD4 T-cell TFH': '0.5', 'Terminal effector memory CD4 T-cell': '0.0', 'Central memory CD8 T-cell': '4.8', 'Effector memory CD8 T-cell': '0.0', 'Terminal effector memory CD8 T-cell': '0.6', 'Non-switched memory B-cell': '0.0', 'Plasmablast': '3.3', 'Switched memory B-cell': '0.0', 'Exhausted memory B-cell': '0.7', 'Progenitor cell': '2.3', 'Memory T-reg': '1.3', 'Naive CD4 T-cell activated': '0.3', 'Naive CD8 T-cell activated': '0.6', 'Naive T-reg': '0.1'}
1O6S, 2O72, 2OMT, 2OMU, 2OMV, 2OMX, 2OMY, 2OMZ, 3FF7, 3FF8, 3L6X, 3L6Y, 4ZT1, 4ZTE, 6CXY, 6OLE, 6OLF, 6OLG, 6VEL, 7STZ, 8H62
{'Adipose Tissue': 1.2125261088039867, 'Adrenal Gland': 0.1914223992248062, 'Bladder': 39.2033519047619, 'Blood': 1.340954264800861, 'Blood Vessel': 0.3121561692883895, 'Brain': 0.8550442199091597, 'Breast': 38.54918344226579, 'Cervix Uteri': 23.539115789473684, 'Colon': 43.41292142490372, 'Esophagus': 53.97513367404844, 'Fallopian Tube': 14.900277777777776, 'Heart': 0.119140469221835, 'Kidney': 25.040449438202245, 'Liver': 26.60802654867257, 'Lung': 35.447986366782004, 'Muscle': 0.1378936151930261, 'Nerve': 17.518468982229404, 'Ovary': 3.6515122222222223, 'Pancreas': 56.89676829268293, 'Pituitary': 24.68741660777385, 'Prostate': 61.279967346938776, 'Salivary Gland': 92.01685185185184, 'Skin': 79.77571720232172, 'Small Intestine': 71.7519320855615, 'Spleen': 10.061029045643156, 'Stomach': 58.07813805013927, 'Testis': 0.8144204986149585, 'Thyroid': 135.176797856049, 'Uterus': 1.442593943661972, 'Vagina': 86.52345512820513}
HOXC10
MTCPRNVTPNSYAEPLAAPGGGERYSRSAGMYMQSGSDFNCGVMRGCGLAPSLSKRDEGSSPSLALNTYPSYLSQLDSWGDPKAAYRLEQPVGRPLSSCSYPPSVKEENVCCMYSAEKRAKSGPEAALYSHPLPESCLGEHEVPVPSYYRASPSYSALDKTPHCSGANDFEAPFEQRASLNPRAEHLESPQLGGKVSFPETPKSDSQTPSPNEIKTEQSLAGPKGSPSESEKERAKAADSSPDTSDNEAKEEIKAENTTGNWLTAKSGRKKRCPYTKHQTLELEKEFLFNMYLTRERRLEISKTINLTDRQVKIWFQNRRMKLKKMNRENRIRELTSNFNFT
Homo sapiens
Nucleus
Tissue enriched (skeletal)
{'Ciliated cells': '0.0', 'Basal respiratory cells': '0.0', 'Club cells': '0.0', 'Ionocytes': '0.0', 'Mucus glandular cells': '0.0', 'Serous glandular cells': '0.0', 'Gastric mucus-secreting cells': '0.0', 'Proximal enterocytes': '0.1', 'Paneth cells': '0.0', 'Distal enterocytes': '0.0', 'Intestinal goblet cells': '0.0', 'Exocrine glandular cells': '-0.234', 'Basal prostatic cells': '0.0', 'Prostatic glandular cells': '0.0', 'Breast glandular cells': '0.447', 'Breast myoepithelial cells': '0.463', 'Glandular and luminal cells': '0.0', 'Secretory cells': '0.0', 'Basal keratinocytes': '10.2', 'Suprabasal keratinocytes': '9.6', 'Basal squamous epithelial cells': '0.7', 'Squamous epithelial cells': '0.1', 'Alveolar cells type 1': '0.020', 'Alveolar cells type 2': '-0.098', 'Salivary duct cells': '0.0', 'Ductal cells': '0.099', 'Hepatocytes': '0.052', 'Cholangiocytes': '0.0', 'Proximal tubular cells': '0.159', 'Distal tubular cells': '27.7', 'Collecting duct cells': '17.5', 'Mesothelial cells': '0.021', 'Sertoli cells': '0.176', 'Granulosa cells': '2.8', 'Enteroendocrine cells': '0.0', 'Pancreatic endocrine cells': '0.0', 'Leydig cells': '0.167', 'Excitatory neurons': '0.0', 'Inhibitory neurons': '0.0', 'Cone photoreceptor cells': '0.0', 'Rod photoreceptor cells': '0.0', 'Bipolar cells': '0.0', 'Horizontal cells': '0.0', 'Astrocytes': '0.0', 'Oligodendrocyte precursor cells': '0.0', 'Oligodendrocytes': '0.0', 'Microglial cells': '0.0', 'Muller glia cells': '0.1', 'Schwann cells': '0.248', 'Spermatogonia': '0.225', 'Spermatocytes': '0.432', 'Early spermatids': '-0.086', 'Late spermatids': '-0.136', 'Oocytes': '0.0', 'Cytotrophoblasts': '0.0', 'Syncytiotrophoblasts': '0.0', 'Extravillous trophoblasts': '0.1', 'Endothelial cells': '0.4', 'Lymphatic endothelial cells': '0.0', 'Cardiomyocytes': '0.000', 'Skeletal myocytes': '-0.132', 'Smooth muscle cells': '5.6', 'Adipocytes': '0.6', 'Melanocytes': '0.050', 'Fibroblasts': '7.2', 'Peritubular cells': '0.016', 'Endometrial stromal cells': '0.9', 'Ovarian stromal cells': '4.6', 'Undifferentiated cells': '0.1', 'T-cells': '0.4', 'B-cells': '0.4', 'Plasma cells': '0.0', 'Nk-cells': '0.0', 'Granulocytes': '0.0', 'Monocytes': '0.0', 'Macrophages': '0.7', 'Hofbauer cells': '0.0', 'Kupffer cells': '0.0', 'Dendritic cells': '0.0', 'Langerhans cells': '0.088', 'Erythroid cells': '-0.045', 'Adipocytes (Subcutaneous)': '-0.210', 'Adipocytes (Visceral)': '-0.177', 'Breast glandular cells (progenitors)': '0.508', 'Adipocytes (Breast)': '-0.405', 'Colon enterocytes': '-0.007', 'Colon enteroendocrine cells': '0.026', 'Enteric glia cells': '0.173', 'Mitotic cells (Colon)': '0.011', 'Mitotic cells (Heart)': '0.045', 'Podocytes': '-0.014', 'Ascending Loop of Henle cells': '0.493', 'Intercalated cells': '0.010', 'Cholangiocyte': '0.043', 'NK-cells (Liver)': '0.036', 'Respiratory ciliated cells': '-0.014', 'Mitotic cells (Lung)': '-0.105', 'NK-cells (Lung)': '0.027', 'B-cells (Lung)': '0.058', 'Alpha cells': '0.063', 'Beta cells': '-0.016', 'Prostate glandular cells': '-0.254', 'Prostate basal glandular cells': '-0.323', 'Urothelial cells': '-0.254', 'Keratinocyte (other)': '-0.014', 'Keratinocyte (granular)': '-0.141', 'Hair cortex cells': '0.128', 'Inner root sheath cells': '0.150', 'Outer root sheath cells': '0.275', 'Sebaceous gland cells': '-0.005', 'Eccrine sweat gland cells': '0.418', 'Adipocytes (Skin)': '0.145', 'Mitotic cells (Skin)': '0.271', 'Parietal cells': '-0.030', 'Chief cells': '-0.033', 'Gastric mucous cells': '-0.069', 'Gastric enteroendocrine cells': '-0.030', 'Mitotic cells (Stomach)': '0.016', 'Parafollicular cells': '-0.090', 'Thyroid glandular cells': '-0.013', 'Mitotic cells (Thyroid)': '0.082', 'Adrenal cortex cells': '0.213', 'Adrenal medulla cells': '0.189', 'Mitotic cells (Adrenal gland)': '0.015', 'Minor salivary glandular cells': '-0.013', 'Minor salivary gland ductal cells': '-0.102', 'Minor salivary gland basal cells': '0.063', 'Mitotic cells (Minor salivary gland)': '0.098', 'Adipocytes (Minor salivary gland)': '0.017', 'Somatotropes': '-0.092', 'Lactotropes': '-0.066', 'Gonadotropes': '-0.085', 'Corticotropes': '-0.078', 'Thyrotropes': '-0.075', 'Undifferentiated cells (Pituitary gland)': '0.111', 'Mitotic cells (Spleen)': '-0.018', 'Platelets': '-0.069', 'Erythrocytes': '-0.057', 'Hematopoietic stem cells': '-0.053', 'B-cells (Spleen)': '0.025', 'NK-cells (Spleen)': '-0.078', 'Amygdala excitatory': '0.0', 'Cerebellar inhibitory': '0.1', 'Cge interneuron': '0.0', 'Deep-layer corticothalamic and 6b': '0.0', 'Deep-layer intratelencephalic': '0.0', 'Deep-layer near-projecting': '0.0', 'Eccentric medium spiny neuron': '0.0', 'Hippocampal ca1-3': '0.2', 'Hippocampal ca4': '0.0', 'Hippocampal dentate gyrus': '0.0', 'Lamp5-lhx6 and chandelier': '0.0', 'Lower rhombic lip': '0.0', 'Mammillary body': '0.0', 'Medium spiny neuron': '0.0', 'Mge interneuron': '0.0', 'Midbrain-derived inhibitory': '0.0', 'Miscellaneous': '0.0', 'Splatter': '0.0', 'Thalamic excitatory': '0.0', 'Upper rhombic lip': '0.0', 'Upper-layer intratelencephalic': '0.0', 'Astrocyte': '0.0', 'Bergmann glia': '0.0', 'Central nervous system macrophage': '0.0', 'Choroid plexus epithelial cell': '0.0', 'Committed oligodendrocyte precursor': '0.0', 'Ependymal cell': '0.0', 'Oligodendrocyte': '0.0', 'Oligodendrocyte precursor cell': '0.0', 'Endothelial cell': '0.0', 'Pericyte': '0.0', 'Vascular associated smooth muscle cell': '0.0', 'Fibroblast': '0.0', 'Leukocyte': '0.0', 'Basophil': '0.0', 'Eosinophil': '0.0', 'Neutrophil': '0.0', 'Classical monocyte': '0.0', 'Non-classical monocyte': '0.0', 'Intermediate monocyte': '0.0', 'T-reg': '0.0', 'GdT-cell': '0.0', 'MAIT T-cell': '0.0', 'Memory CD4 T-cell': '0.0', 'Naive CD4 T-cell': '0.0', 'Memory CD8 T-cell': '0.0', 'Naive CD8 T-cell': '0.0', 'Memory B-cell': '0.0', 'Naive B-cell': '0.0', 'Plasmacytoid DC': '0.0', 'Myeloid DC': '0.0', 'NK-cell': '0.0', 'Total PBMC': '0.0', 'Vd2 gdTCR': '0.0', 'Memory CD4 T-cell Th1\\/Th17': '0.0', 'Memory CD4 T-cell Th17': '0.0', 'Memory CD4 T-cell Th2': '0.0', 'Non-Vd2 gdTCR': '0.0', 'Memory CD4 T-cell Th1': '0.0', 'Memory CD4 T-cell TFH': '0.0', 'Terminal effector memory CD4 T-cell': '0.0', 'Central memory CD8 T-cell': '0.0', 'Effector memory CD8 T-cell': '0.0', 'Terminal effector memory CD8 T-cell': '0.0', 'Non-switched memory B-cell': '0.0', 'Plasmablast': '0.0', 'Switched memory B-cell': '0.0', 'Exhausted memory B-cell': '0.0', 'Progenitor cell': '0.0', 'Memory T-reg': '0.0', 'Naive CD4 T-cell activated': '0.0', 'Naive CD8 T-cell activated': '0.0', 'Naive T-reg': '0.0'}
null
{'Adipose Tissue': 14.054818542358804, 'Adrenal Gland': 0.8364182558139535, 'Bladder': 1.4036333333333335, 'Blood': 0.1086186544671689, 'Blood Vessel': 24.98999456029963, 'Brain': 0.0454970022710068, 'Breast': 3.3948529411764703, 'Cervix Uteri': 1.6972157894736843, 'Colon': 0.4591807856225931, 'Esophagus': 0.1328764692041522, 'Fallopian Tube': 21.676717777777775, 'Heart': 0.0338635772357723, 'Kidney': 27.975876404494382, 'Liver': 0.0285249646017699, 'Lung': 0.1107369757785467, 'Muscle': 65.65803237858033, 'Nerve': 6.716636510500808, 'Ovary': 4.359101222222223, 'Pancreas': 0.0520476798780487, 'Pituitary': 0.0475809399293286, 'Prostate': 1.4719703673469389, 'Salivary Gland': 0.0354305555555555, 'Skin': 44.27386622443339, 'Small Intestine': 4.316685775401069, 'Spleen': 0.0417082572614107, 'Stomach': 0.0461333899721448, 'Testis': 2.776337950138504, 'Thyroid': 0.1062438376722817, 'Uterus': 5.149835985915493, 'Vagina': 2.6226684615384617}
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0.96, 0.93, 0.54, 0.64, 0.28, 0.54, 0.52, 0.16, 0.51, 0.88, 0.6, 0.4, 0.88, 0.95, 0.33, 0.56, 0.73, 0.39, 0.06, 0.61, 0.75, 0.47, 0.19, 0.87, 0.7, 0.97, 0.94, 0.97]
[53.51, 61.05, 54.07, 78.72, 58.9, 57.55, 61.9, 62.32, 57.72, 53.11, 50.37, 49.21, 55.97, 46.29, 57.56, 48.55, 52.74, 55.02, 50.58, 47.73, 46.12, 42.35, 49.42, 47.17, 46.34, 47.05, 48.29, 46.04, 51.03, 44.45, 60.63, 52.98, 64.07, 43.8, 44.15, 41.75, 46.67, 45.87, 53.88, 45.27, 36.84, 46.78, 48.88, 56.52, 52.2, 47.31, 42.15, 48.79, 52.38, 59.75, 55.97, 44.3, 54.53, 51.85, 53.61, 51.63, 47.05, 45.77, 44.4, 37.16, 44.74, 40.49, 43.31, 51.56, 38.69, 50.27, 41.93, 45.1, 48.12, 58.34, 51.23, 54.47, 55.67, 58.27, 48.88, 55.8, 52.09, 53.4, 46.53, 46.33, 42.97, 51.77, 52.65, 49.42, 48.86, 46.15, 43.82, 57.1, 57.09, 45.36, 63.25, 49.51, 53.64, 56.47, 57.4, 56.87, 60.05, 53.16, 45.46, 62.41, 58.35, 66.04, 58.63, 54.97, 55.35, 58.23, 56.49, 52.97, 51.13, 47.74, 39.24, 40.55, 52.71, 39.51, 43.76, 37.95, 48.17, 47.51, 41.27, 41.86, 55.44, 42.11, 50.39, 54.82, 49.21, 44.91, 48.15, 54.66, 43.98, 45.98, 43.68, 53.59, 43.87, 47.8, 44.68, 40.81, 38.09, 42.11, 41.73, 38.41, 50.76, 52.3, 58.53, 73.48, 61.33, 70.94, 67.69, 78.07, 68.45, 67.92, 60.98, 55.95, 53.37, 53.69, 43.36, 50.98, 40.88, 53.74, 43.4, 50.85, 41.23, 52.64, 43.7, 43.08, 40.83, 43.92, 45.73, 51.3, 45.79, 50.79, 43.64, 50.13, 50.85, 38.97, 49.75, 42.94, 45.76, 42.73, 40.95, 53.43, 47.22, 48.6, 48.62, 42.01, 54.38, 40.18, 49.45, 45.79, 41.01, 45.28, 41.45, 45.44, 41.12, 47.93, 42.7, 46.5, 42.15, 41.07, 49.69, 43.64, 41.98, 50.15, 41.89, 51.74, 45.73, 45.96, 48.59, 38.5, 44.54, 40.13, 52.41, 40.83, 42.81, 54.45, 46.85, 50.0, 48.3, 50.67, 48.08, 46.97, 50.75, 40.68, 49.53, 39.67, 42.85, 46.74, 41.15, 38.91, 44.23, 46.59, 50.29, 51.12, 50.76, 49.49, 46.42, 56.07, 44.97, 54.81, 50.86, 59.2, 55.99, 65.02, 45.15, 47.22, 48.63, 47.13, 53.92, 45.54, 53.53, 53.18, 55.51, 49.02, 62.48, 52.09, 53.46, 57.1, 51.73, 63.07, 63.32, 58.56, 60.47, 69.2, 69.44, 66.8, 64.35, 63.55, 65.57, 70.93, 78.17, 84.15, 88.17, 91.76, 93.4, 96.93, 98.28, 98.6, 98.51, 98.5, 98.71, 98.58, 98.57, 98.6, 98.82, 98.7, 98.46, 98.51, 98.72, 98.11, 98.07, 97.84, 98.05, 98.59, 98.16, 98.41, 98.42, 98.58, 98.51, 98.68, 98.59, 98.63, 98.49, 98.64, 98.44, 98.35, 98.29, 98.44, 98.16, 98.48, 98.55, 98.36, 98.35, 98.74, 98.53, 98.63, 98.71, 98.81, 98.69, 98.64, 98.7, 98.66, 98.57, 98.27, 97.64, 97.71, 96.99, 95.51, 94.27, 93.44, 93.65, 91.88, 90.89, 91.81, 91.35, 88.79, 87.69, 87.25, 82.82, 70.99, 69.63, 64.04, 51.08, 44.34]
[0.96, 0.94, 0.95, 0.9, 0.9, 0.93, 0.75, 0.91, 0.82, 0.95, 0.9, 1.0, 0.93, 0.81, 0.92, 0.84, 0.96, 1.0, 1.0, 0.99, 1.0, 1.0, 1.0, 1.0, 0.99, 0.98, 0.99, 0.98, 1.0, 1.0, 1.0, 0.85, 1.0, 0.82, 1.0, 1.0, 0.9, 1.0, 0.93, 0.91, 0.91, 0.74, 0.89, 0.97, 0.95, 0.97, 0.88, 0.92, 0.96, 0.98, 0.98, 0.99, 0.98, 0.99, 1.0, 1.0, 1.0, 1.0, 1.0, 0.99, 1.0, 1.0, 0.99, 0.98, 1.0, 0.96, 0.88, 0.96, 0.89, 0.86, 0.62, 0.77, 0.79, 0.65, 0.79, 0.65, 0.84, 0.81, 0.87, 0.87, 0.71, 0.99, 0.87, 0.64, 0.96, 0.91, 0.99, 1.0, 0.96, 0.95, 0.92, 0.95, 0.92, 0.94, 1.0, 0.91, 0.89, 0.87, 0.73, 0.86, 0.86, 0.78, 0.94, 0.88, 0.89, 0.93, 0.86, 0.78, 0.78, 0.62, 0.74, 0.83, 0.81, 0.95, 0.91, 0.94, 0.98, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 0.95, 1.0, 1.0, 0.95, 1.0, 0.95, 1.0, 0.96, 1.0, 0.99, 0.99, 1.0, 0.83, 0.96, 0.83, 0.91, 0.82, 0.76, 0.76, 0.54, 0.71, 0.88, 0.8, 0.72, 0.9, 0.57, 0.86, 0.65, 0.91, 0.86, 0.84, 0.96, 0.92, 0.96, 0.94, 0.95, 0.87, 0.99, 0.8, 0.99, 1.0, 1.0, 1.0, 0.96, 0.98, 0.9, 0.97, 0.83, 0.99, 0.83, 0.99, 0.97, 1.0, 0.97, 0.99, 0.98, 0.87, 0.98, 0.78, 0.98, 1.0, 0.98, 0.9, 1.0, 0.96, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 0.98, 1.0, 0.93, 0.96, 0.96, 0.97, 1.0, 1.0, 0.97, 1.0, 0.96, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 0.99, 0.96, 0.92, 0.97, 0.94, 1.0, 0.97, 0.96, 0.88, 0.93, 0.78, 0.81, 0.86, 0.82, 0.9, 0.75, 0.96, 0.73, 0.59, 0.92, 0.84, 0.25, 0.46, 0.86, 0.89, 0.7, 0.5, 0.9, 0.59, 0.84, 0.84, 0.95, 0.79, 0.95, 0.9, 0.92, 0.36, 0.54, 0.77, 0.55, 0.13, 0.36, 0.6, 0.24, 0.0, 0.29, 0.54, 0.09, 0.04, 0.79, 0.79, 0.46, 0.41, 0.68, 0.18, 0.59, 0.61, 0.71, 0.39, 0.17, 0.36, 0.4, 0.07, 0.16, 0.77, 0.68, 0.03, 0.81, 0.09, 0.54, 0.19, 0.71, 0.34, 0.01, 0.6, 0.34, 0.14, 0.04, 0.6, 0.56, 0.18, 0.31, 0.56, 0.56, 0.38, 0.62, 0.64, 0.47, 0.61, 0.7, 0.41, 0.4, 0.64, 0.55, 0.6, 0.55, 0.54, 0.49, 0.56, 0.81, 0.77, 0.72, 0.94, 0.96]
null
Component of an E-cadherin/ catenin adhesion complex composed of at least E-cadherin/CDH1, beta-catenin/CTNNB1 or gamma-catenin/JUP, and potentially alpha-catenin/CTNNA1. Forms a ternary complex composed of ADAM10, CADH1 and EPHA4,
null
null
KLRG1, SPEF1, DLGAP5, AJAP1, RAPGEF2, RAB8B, PIP5K1C, PKP2, TRPV4, CTNNB1, CAV1, DDR1, TBC1D2, CTNNA1, JUP, CTNND1, PSEN1, LIMA1, CDH1, JUP, ADAM10, CADH1 , EPHA4,
null
null
null
null
Homodimer
null
79.91949
0.474025
59.743538
0.826842
2,212
P12830
Q9NZH5-2
null
degron_data
CDH1
MGPWSRSLSALLLLLQVSSWLCQEPEPCHPGFDAESYTFTVPRRHLERGRVLGRVNFEDCTGRQRTAYFSLDTRFKVGTDGVITVKRPLRFHNPQIHFLVYAWDSTYRKFSTKVTLNTVGHHHRPPPHQASVSGIQAELLTFPNSSPGLRRQKRDWVIPPISCPENEKGPFPKNLVQIKSNKDKEGKVFYSITGQGADTPPVGVFIIERETGWLKVTEPLDRERIATYTLFSHAVSSNGNAVEDPMEILITVTDQNDNKPEFTQEVFKGSVMEGALPGTSVMEVTATDADDDVNTYNAAIAYTILSQDPELPDKNMFTINRNTGVISVVTTGLDRESFPTYTLVVQAADLQGEGLSTTATAVITVTDTNDNPPIFNPTTYKGQVPENEANVVITTLKVTDADAPNTPAWEAVYTILNDDGGQFVVTTNPVNNDGILKTAKGLDFEAKQQYILHVAVTNVVPFEVSLTTSTATVTVDVLDVNEAPIFVPPEKRVEVSEDFGVGQEITSYTAQEPDTFMEQKITYRIWRDTANWLEINPDTGAISTRAELDREDFEHVKNSTYTALIIATDNGSPVATGTGTLLLILSDVNDNAPIPEPRTIFFCERNPKPQVINIIDADLPPNTSPFTAELTHGASANWTIQYNDPTQESIILKPKMALEVGDYKINLKLMDNQNKDQVTTLEVSVCDCEGAAGVCRKAQPVEAGLQIPAILGILGGILALLILILLLLLFLRRRAVVKEPLLPPEDDTRDNVYYYDEEGGGEEDQDFDLSQLHRGLDARPEVTRNDVAPTLMSVPRYLPRPANPDEIGNFIDENLKAADTDPTAPPYDSLLVFDYEGSGSEAASLSSLNSSESDKDQDYDYLNEWGNRFKKLADMYGGGEDD
Homo sapiens
Cell junction, adherens junction, Cell membrane, Endosome, Golgi apparatus, trans-Golgi network, Cytoplasm, Cell junction, desmosome
Tissue enhanced (parathyroid)
{'Ciliated cells': '119.1', 'Basal respiratory cells': '71.1', 'Club cells': '97.3', 'Ionocytes': '81.0', 'Mucus glandular cells': '155.0', 'Serous glandular cells': '67.8', 'Gastric mucus-secreting cells': '133.2', 'Proximal enterocytes': '140.9', 'Paneth cells': '125.1', 'Distal enterocytes': '307.5', 'Intestinal goblet cells': '173.5', 'Exocrine glandular cells': '-0.605', 'Basal prostatic cells': '68.3', 'Prostatic glandular cells': '186.7', 'Breast glandular cells': '0.773', 'Breast myoepithelial cells': '0.700', 'Glandular and luminal cells': '313.0', 'Secretory cells': '82.3', 'Basal keratinocytes': '102.5', 'Suprabasal keratinocytes': '162.6', 'Basal squamous epithelial cells': '51.0', 'Squamous epithelial cells': '106.9', 'Alveolar cells type 1': '0.437', 'Alveolar cells type 2': '0.706', 'Salivary duct cells': '95.9', 'Ductal cells': '0.541', 'Hepatocytes': '0.600', 'Cholangiocytes': '129.7', 'Proximal tubular cells': '0.042', 'Distal tubular cells': '0.0', 'Collecting duct cells': '143.9', 'Mesothelial cells': '0.799', 'Sertoli cells': '0.252', 'Granulosa cells': '12.9', 'Enteroendocrine cells': '92.4', 'Pancreatic endocrine cells': '78.1', 'Leydig cells': '0.264', 'Excitatory neurons': '0.7', 'Inhibitory neurons': '1.3', 'Cone photoreceptor cells': '0.0', 'Rod photoreceptor cells': '0.0', 'Bipolar cells': '0.2', 'Horizontal cells': '0.6', 'Astrocytes': '0.6', 'Oligodendrocyte precursor cells': '0.5', 'Oligodendrocytes': '29.9', 'Microglial cells': '0.9', 'Muller glia cells': '0.1', 'Schwann cells': '0.131', 'Spermatogonia': '0.392', 'Spermatocytes': '0.193', 'Early spermatids': '-0.217', 'Late spermatids': '-0.290', 'Oocytes': '16.9', 'Cytotrophoblasts': '119.2', 'Syncytiotrophoblasts': '45.0', 'Extravillous trophoblasts': '24.9', 'Endothelial cells': '6.1', 'Lymphatic endothelial cells': '0.4', 'Cardiomyocytes': '0.135', 'Skeletal myocytes': '0.107', 'Smooth muscle cells': '5.8', 'Adipocytes': '2.1', 'Melanocytes': '0.335', 'Fibroblasts': '6.5', 'Peritubular cells': '0.210', 'Endometrial stromal cells': '27.7', 'Ovarian stromal cells': '0.7', 'Undifferentiated cells': '101.6', 'T-cells': '2.9', 'B-cells': '4.4', 'Plasma cells': '6.1', 'Nk-cells': '0.0', 'Granulocytes': '8.4', 'Monocytes': '0.0', 'Macrophages': '6.0', 'Hofbauer cells': '4.3', 'Kupffer cells': '1.0', 'Dendritic cells': '5.9', 'Langerhans cells': '0.304', 'Erythroid cells': '0.036', 'Adipocytes (Subcutaneous)': '-0.081', 'Adipocytes (Visceral)': '-0.209', 'Breast glandular cells (progenitors)': '0.538', 'Adipocytes (Breast)': '-0.689', 'Colon enterocytes': '0.790', 'Colon enteroendocrine cells': '0.112', 'Enteric glia cells': '-0.048', 'Mitotic cells (Colon)': '0.299', 'Mitotic cells (Heart)': '0.120', 'Podocytes': '-0.118', 'Ascending Loop of Henle cells': '0.475', 'Intercalated cells': '0.212', 'Cholangiocyte': '0.090', 'NK-cells (Liver)': '-0.005', 'Respiratory ciliated cells': '-0.012', 'Mitotic cells (Lung)': '0.071', 'NK-cells (Lung)': '-0.266', 'B-cells (Lung)': '-0.296', 'Alpha cells': '0.270', 'Beta cells': '0.152', 'Prostate glandular cells': '0.764', 'Prostate basal glandular cells': '0.540', 'Urothelial cells': '0.205', 'Keratinocyte (other)': '0.510', 'Keratinocyte (granular)': '0.055', 'Hair cortex cells': '0.080', 'Inner root sheath cells': '0.131', 'Outer root sheath cells': '0.175', 'Sebaceous gland cells': '0.156', 'Eccrine sweat gland cells': '-0.207', 'Adipocytes (Skin)': '-0.244', 'Mitotic cells (Skin)': '0.442', 'Parietal cells': '0.654', 'Chief cells': '0.649', 'Gastric mucous cells': '0.781', 'Gastric enteroendocrine cells': '0.590', 'Mitotic cells (Stomach)': '0.445', 'Parafollicular cells': '0.173', 'Thyroid glandular cells': '0.865', 'Mitotic cells (Thyroid)': '-0.081', 'Adrenal cortex cells': '0.051', 'Adrenal medulla cells': '0.087', 'Mitotic cells (Adrenal gland)': '0.072', 'Minor salivary glandular cells': '0.371', 'Minor salivary gland ductal cells': '-0.142', 'Minor salivary gland basal cells': '0.582', 'Mitotic cells (Minor salivary gland)': '0.567', 'Adipocytes (Minor salivary gland)': '0.050', 'Somatotropes': '0.121', 'Lactotropes': '0.322', 'Gonadotropes': '0.330', 'Corticotropes': '0.180', 'Thyrotropes': '0.496', 'Undifferentiated cells (Pituitary gland)': '-0.108', 'Mitotic cells (Spleen)': '-0.228', 'Platelets': '-0.050', 'Erythrocytes': '-0.158', 'Hematopoietic stem cells': '-0.211', 'B-cells (Spleen)': '0.266', 'NK-cells (Spleen)': '0.309', 'Amygdala excitatory': '1.0', 'Cerebellar inhibitory': '0.9', 'Cge interneuron': '0.7', 'Deep-layer corticothalamic and 6b': '1.5', 'Deep-layer intratelencephalic': '0.7', 'Deep-layer near-projecting': '0.7', 'Eccentric medium spiny neuron': '0.6', 'Hippocampal ca1-3': '1.9', 'Hippocampal ca4': '1.2', 'Hippocampal dentate gyrus': '1.1', 'Lamp5-lhx6 and chandelier': '0.5', 'Lower rhombic lip': '0.8', 'Mammillary body': '0.6', 'Medium spiny neuron': '0.7', 'Mge interneuron': '1.7', 'Midbrain-derived inhibitory': '0.7', 'Miscellaneous': '0.9', 'Splatter': '3.8', 'Thalamic excitatory': '0.5', 'Upper rhombic lip': '0.8', 'Upper-layer intratelencephalic': '0.6', 'Astrocyte': '4.4', 'Bergmann glia': '0.2', 'Central nervous system macrophage': '0.6', 'Choroid plexus epithelial cell': '52.1', 'Committed oligodendrocyte precursor': '41.5', 'Ependymal cell': '4.8', 'Oligodendrocyte': '53.1', 'Oligodendrocyte precursor cell': '2.4', 'Endothelial cell': '0.7', 'Pericyte': '0.3', 'Vascular associated smooth muscle cell': '0.0', 'Fibroblast': '17.4', 'Leukocyte': '1.1', 'Basophil': '0.0', 'Eosinophil': '0.0', 'Neutrophil': '0.0', 'Classical monocyte': '0.0', 'Non-classical monocyte': '0.0', 'Intermediate monocyte': '0.0', 'T-reg': '2.3', 'GdT-cell': '0.0', 'MAIT T-cell': '0.0', 'Memory CD4 T-cell': '0.0', 'Naive CD4 T-cell': '0.1', 'Memory CD8 T-cell': '0.2', 'Naive CD8 T-cell': '0.3', 'Memory B-cell': '0.0', 'Naive B-cell': '0.1', 'Plasmacytoid DC': '46.6', 'Myeloid DC': '8.5', 'NK-cell': '0.1', 'Total PBMC': '0.7', 'Vd2 gdTCR': '0.0', 'Memory CD4 T-cell Th1\\/Th17': '0.1', 'Memory CD4 T-cell Th17': '0.2', 'Memory CD4 T-cell Th2': '2.9', 'Non-Vd2 gdTCR': '0.1', 'Memory CD4 T-cell Th1': '0.3', 'Memory CD4 T-cell TFH': '0.5', 'Terminal effector memory CD4 T-cell': '0.0', 'Central memory CD8 T-cell': '4.8', 'Effector memory CD8 T-cell': '0.0', 'Terminal effector memory CD8 T-cell': '0.6', 'Non-switched memory B-cell': '0.0', 'Plasmablast': '3.3', 'Switched memory B-cell': '0.0', 'Exhausted memory B-cell': '0.7', 'Progenitor cell': '2.3', 'Memory T-reg': '1.3', 'Naive CD4 T-cell activated': '0.3', 'Naive CD8 T-cell activated': '0.6', 'Naive T-reg': '0.1'}
1O6S, 2O72, 2OMT, 2OMU, 2OMV, 2OMX, 2OMY, 2OMZ, 3FF7, 3FF8, 3L6X, 3L6Y, 4ZT1, 4ZTE, 6CXY, 6OLE, 6OLF, 6OLG, 6VEL, 7STZ, 8H62
{'Adipose Tissue': 1.2125261088039867, 'Adrenal Gland': 0.1914223992248062, 'Bladder': 39.2033519047619, 'Blood': 1.340954264800861, 'Blood Vessel': 0.3121561692883895, 'Brain': 0.8550442199091597, 'Breast': 38.54918344226579, 'Cervix Uteri': 23.539115789473684, 'Colon': 43.41292142490372, 'Esophagus': 53.97513367404844, 'Fallopian Tube': 14.900277777777776, 'Heart': 0.119140469221835, 'Kidney': 25.040449438202245, 'Liver': 26.60802654867257, 'Lung': 35.447986366782004, 'Muscle': 0.1378936151930261, 'Nerve': 17.518468982229404, 'Ovary': 3.6515122222222223, 'Pancreas': 56.89676829268293, 'Pituitary': 24.68741660777385, 'Prostate': 61.279967346938776, 'Salivary Gland': 92.01685185185184, 'Skin': 79.77571720232172, 'Small Intestine': 71.7519320855615, 'Spleen': 10.061029045643156, 'Stomach': 58.07813805013927, 'Testis': 0.8144204986149585, 'Thyroid': 135.176797856049, 'Uterus': 1.442593943661972, 'Vagina': 86.52345512820513}
PTTG2
MATLIYVDKEIGEPGTRVAAKDVLKLESRPSIKALDGISQVLTRRFGKTYDAPSALPKATRKALGTVNRATEKSVKTNGPRKQKQPSFSAKKMTEKTVKTKSSVPASDDAYPEIEKFFPFNLLDFESFDLPEERQIAHLPLSGVPLMILDEEGELEKLFQLGPPSPVKMPSPPWECNLFAVSFKHSVDPGC
Homo sapiens
null
Not found
{}
null
{'Adipose Tissue': 0.4639726328903655, 'Adrenal Gland': 0.0897329457364341, 'Bladder': 1.1418, 'Blood': 0.748422691065662, 'Blood Vessel': 1.9751588389513108, 'Brain': 0.4841600075700227, 'Breast': 0.3305101089324618, 'Cervix Uteri': 0.7931526315789474, 'Colon': 1.618507997432606, 'Esophagus': 0.8111101522491349, 'Fallopian Tube': 1.242748888888889, 'Heart': 0.6481920441347271, 'Kidney': 0.3338534831460674, 'Liver': 0.1867276548672566, 'Lung': 0.8233365051903114, 'Muscle': 0.5557330635118306, 'Nerve': 0.4343408885298869, 'Ovary': 0.4670455, 'Pancreas': 0.1599472865853658, 'Pituitary': 0.4033778798586572, 'Prostate': 0.6806202857142857, 'Salivary Gland': 0.1576929629629629, 'Skin': 0.1475455389718076, 'Small Intestine': 0.814641871657754, 'Spleen': 1.4785477178423236, 'Stomach': 0.547606991643454, 'Testis': 0.1705815789473684, 'Thyroid': 0.4332415467075038, 'Uterus': 1.848892253521127, 'Vagina': 0.5994922435897436}
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0.32, 0.01, 0.22, 0.0, 0.05, 0.0, 0.41, 0.46, 0.42, 0.82, 0.48, 0.4, 0.5, 0.17, 0.62, 0.06, 0.32, 0.0, 0.25, 0.0, 0.42, 0.08, 0.41, 0.27, 0.16, 0.04, 0.36, 0.32, 0.2, 0.0, 0.52, 0.04, 0.66, 0.47, 0.52, 0.78, 0.09, 0.77, 0.08, 0.6, 0.0, 0.31, 0.03, 0.58, 0.47, 0.59, 0.44, 0.23, 0.54, 0.1, 0.18, 0.45, 0.0, 0.53, 0.11, 0.59, 0.17, 0.51, 0.01, 0.19, 0.71, 0.77, 0.3, 0.44, 0.08, 0.14, 0.52, 0.05, 0.37, 0.1, 0.42, 0.23, 0.61, 0.43, 0.22, 0.96, 0.54, 0.4, 0.3, 0.07, 0.39, 0.17, 0.43, 0.38, 0.3, 0.8, 0.83, 0.44, 0.03, 0.11, 0.0, 0.23, 0.0, 0.31, 0.0, 0.38, 0.58, 0.51, 0.01, 0.49, 0.13, 0.26, 0.69, 0.46, 0.41, 0.51, 0.06, 0.51, 0.03, 0.38, 0.0, 0.06, 0.0, 0.34, 0.08, 0.53, 0.42, 0.88, 0.25, 0.75, 0.49, 1.0, 0.34, 0.86, 0.48, 0.18, 0.52, 0.01, 0.32, 0.0, 0.19, 0.0, 0.3, 0.05, 0.44, 0.27, 0.43, 0.11, 0.31, 0.39, 0.03, 0.55, 0.04, 0.52, 0.51, 0.64, 0.57, 0.19, 0.68, 0.13, 0.84, 0.06, 0.31, 0.07, 0.69, 0.26, 0.37, 0.53, 0.67, 0.5, 0.56, 0.14, 0.18, 0.47, 0.01, 0.47, 0.15, 0.61, 0.28, 0.2, 0.02, 0.76, 0.55, 0.31, 0.94, 0.22, 0.57, 0.17, 0.4, 0.07, 0.5, 0.31, 0.7, 0.2, 0.14, 0.3, 0.23, 0.58, 0.07, 0.06, 0.55, 0.15, 0.46, 0.43, 0.64, 0.53, 0.0, 0.18, 0.01, 0.23, 0.02, 0.63, 0.33, 0.79, 0.06, 0.38, 0.07, 0.14, 0.23, 0.68, 0.89, 0.29, 0.06, 0.72, 0.92, 0.24, 0.25, 0.0, 0.46, 0.02, 0.21, 0.01, 0.06, 0.0, 0.05, 0.07, 0.61, 0.17, 0.89, 0.72, 0.66, 0.14, 0.52, 0.07, 0.58, 0.01, 0.26, 0.0, 0.13, 0.0, 0.29, 0.04, 0.46, 0.27, 0.28, 0.23, 0.56, 0.32, 0.25, 0.0, 0.33, 0.05, 0.55, 0.5, 0.58, 0.53, 0.04, 0.27, 0.02, 0.04, 0.37, 0.67, 0.74, 0.35, 0.62, 0.54, 0.26, 0.46, 0.0, 0.47, 0.09, 0.45, 0.15, 0.39, 0.05, 0.44, 0.85, 0.56, 0.11, 0.11, 0.35, 0.42, 0.03, 0.32, 0.12, 0.49, 0.19, 0.25, 0.8, 0.6, 0.09, 0.49, 0.57, 0.36, 0.04, 0.35, 0.28, 0.52, 0.39, 0.5, 0.28, 0.93, 0.47, 0.3, 0.47, 0.08, 0.02, 0.18, 0.01, 0.34, 0.23, 0.55, 0.57, 0.91, 0.1, 0.78, 0.52, 0.34, 0.61, 0.24, 0.75, 0.0, 0.2, 0.02, 0.24, 0.0, 0.18, 0.04, 0.44, 0.59, 0.71, 0.29, 0.52, 0.37, 0.5, 0.11, 0.6, 0.02, 0.48, 0.01, 0.16, 0.04, 0.35, 0.66, 0.47, 0.74, 0.14, 0.62, 0.16, 0.77, 0.79, 0.27, 0.93, 0.69, 0.88, 0.88, 0.85, 0.87, 0.91, 0.92, 0.82, 0.63, 0.75, 0.7, 0.7, 0.38, 0.43, 0.64, 0.55, 0.54, 0.59, 0.45, 0.47, 0.5, 0.58, 0.52, 0.61, 0.57, 0.52, 0.68, 0.44, 0.6, 0.61, 0.58, 0.55, 0.5, 0.61, 0.61, 0.86, 0.86, 0.75, 0.91, 0.96, 0.93, 1.0, 0.87, 0.97, 0.91, 0.95, 0.86, 0.98, 0.93, 0.88, 0.59, 0.87, 0.7, 0.67, 0.85, 0.89, 0.88, 0.91, 0.93, 0.88, 0.99, 0.92, 1.0, 0.79, 0.9, 1.0, 0.94, 1.0, 0.97, 0.96, 0.9, 0.63, 0.68, 0.48, 0.54, 0.8, 0.7, 0.7, 0.95, 0.87, 0.77, 0.84, 0.79, 0.89, 0.95, 0.8, 0.77, 0.51, 0.87, 0.7, 0.52, 0.84, 0.91, 0.51, 0.96, 0.79, 0.92, 0.84, 0.21, 0.89, 0.53, 0.52, 0.89, 0.86, 0.26, 0.91, 0.45, 0.68, 0.84, 0.48, 0.44, 0.51, 0.62, 0.28, 0.59, 0.63, 0.57, 0.15, 0.55, 0.66, 0.1, 0.38, 0.74, 0.65, 0.17, 0.43, 0.66, 0.41, 0.8, 0.75, 0.9, 0.93, 0.52, 0.76, 0.89, 0.87, 0.76, 0.92, 0.91, 0.75, 0.61, 0.96, 0.89, 0.73, 0.97, 0.68, 0.87, 0.55, 0.85, 0.77, 0.69, 0.76, 0.98, 0.83, 0.68, 0.82, 0.74, 0.65, 0.96, 0.93, 0.54, 0.64, 0.28, 0.54, 0.52, 0.16, 0.51, 0.88, 0.6, 0.4, 0.88, 0.95, 0.33, 0.56, 0.73, 0.39, 0.06, 0.61, 0.75, 0.47, 0.19, 0.87, 0.7, 0.97, 0.94, 0.97]
null
null
null
Component of an E-cadherin/ catenin adhesion complex composed of at least E-cadherin/CDH1, beta-catenin/CTNNB1 or gamma-catenin/JUP, and potentially alpha-catenin/CTNNA1. Forms a ternary complex composed of ADAM10, CADH1 and EPHA4,
null
null
KLRG1, SPEF1, DLGAP5, AJAP1, RAPGEF2, RAB8B, PIP5K1C, PKP2, TRPV4, CTNNB1, CAV1, DDR1, TBC1D2, CTNNA1, JUP, CTNND1, PSEN1, LIMA1, CDH1, JUP, ADAM10, CADH1 , EPHA4,
null
null
null
null
Homodimer
null
79.91949
0.474025
null
null
2,730
P12830
Q9P2P5
null
degron_data
CDH1
MGPWSRSLSALLLLLQVSSWLCQEPEPCHPGFDAESYTFTVPRRHLERGRVLGRVNFEDCTGRQRTAYFSLDTRFKVGTDGVITVKRPLRFHNPQIHFLVYAWDSTYRKFSTKVTLNTVGHHHRPPPHQASVSGIQAELLTFPNSSPGLRRQKRDWVIPPISCPENEKGPFPKNLVQIKSNKDKEGKVFYSITGQGADTPPVGVFIIERETGWLKVTEPLDRERIATYTLFSHAVSSNGNAVEDPMEILITVTDQNDNKPEFTQEVFKGSVMEGALPGTSVMEVTATDADDDVNTYNAAIAYTILSQDPELPDKNMFTINRNTGVISVVTTGLDRESFPTYTLVVQAADLQGEGLSTTATAVITVTDTNDNPPIFNPTTYKGQVPENEANVVITTLKVTDADAPNTPAWEAVYTILNDDGGQFVVTTNPVNNDGILKTAKGLDFEAKQQYILHVAVTNVVPFEVSLTTSTATVTVDVLDVNEAPIFVPPEKRVEVSEDFGVGQEITSYTAQEPDTFMEQKITYRIWRDTANWLEINPDTGAISTRAELDREDFEHVKNSTYTALIIATDNGSPVATGTGTLLLILSDVNDNAPIPEPRTIFFCERNPKPQVINIIDADLPPNTSPFTAELTHGASANWTIQYNDPTQESIILKPKMALEVGDYKINLKLMDNQNKDQVTTLEVSVCDCEGAAGVCRKAQPVEAGLQIPAILGILGGILALLILILLLLLFLRRRAVVKEPLLPPEDDTRDNVYYYDEEGGGEEDQDFDLSQLHRGLDARPEVTRNDVAPTLMSVPRYLPRPANPDEIGNFIDENLKAADTDPTAPPYDSLLVFDYEGSGSEAASLSSLNSSESDKDQDYDYLNEWGNRFKKLADMYGGGEDD
Homo sapiens
Cell junction, adherens junction, Cell membrane, Endosome, Golgi apparatus, trans-Golgi network, Cytoplasm, Cell junction, desmosome
Tissue enhanced (parathyroid)
{'Ciliated cells': '119.1', 'Basal respiratory cells': '71.1', 'Club cells': '97.3', 'Ionocytes': '81.0', 'Mucus glandular cells': '155.0', 'Serous glandular cells': '67.8', 'Gastric mucus-secreting cells': '133.2', 'Proximal enterocytes': '140.9', 'Paneth cells': '125.1', 'Distal enterocytes': '307.5', 'Intestinal goblet cells': '173.5', 'Exocrine glandular cells': '-0.605', 'Basal prostatic cells': '68.3', 'Prostatic glandular cells': '186.7', 'Breast glandular cells': '0.773', 'Breast myoepithelial cells': '0.700', 'Glandular and luminal cells': '313.0', 'Secretory cells': '82.3', 'Basal keratinocytes': '102.5', 'Suprabasal keratinocytes': '162.6', 'Basal squamous epithelial cells': '51.0', 'Squamous epithelial cells': '106.9', 'Alveolar cells type 1': '0.437', 'Alveolar cells type 2': '0.706', 'Salivary duct cells': '95.9', 'Ductal cells': '0.541', 'Hepatocytes': '0.600', 'Cholangiocytes': '129.7', 'Proximal tubular cells': '0.042', 'Distal tubular cells': '0.0', 'Collecting duct cells': '143.9', 'Mesothelial cells': '0.799', 'Sertoli cells': '0.252', 'Granulosa cells': '12.9', 'Enteroendocrine cells': '92.4', 'Pancreatic endocrine cells': '78.1', 'Leydig cells': '0.264', 'Excitatory neurons': '0.7', 'Inhibitory neurons': '1.3', 'Cone photoreceptor cells': '0.0', 'Rod photoreceptor cells': '0.0', 'Bipolar cells': '0.2', 'Horizontal cells': '0.6', 'Astrocytes': '0.6', 'Oligodendrocyte precursor cells': '0.5', 'Oligodendrocytes': '29.9', 'Microglial cells': '0.9', 'Muller glia cells': '0.1', 'Schwann cells': '0.131', 'Spermatogonia': '0.392', 'Spermatocytes': '0.193', 'Early spermatids': '-0.217', 'Late spermatids': '-0.290', 'Oocytes': '16.9', 'Cytotrophoblasts': '119.2', 'Syncytiotrophoblasts': '45.0', 'Extravillous trophoblasts': '24.9', 'Endothelial cells': '6.1', 'Lymphatic endothelial cells': '0.4', 'Cardiomyocytes': '0.135', 'Skeletal myocytes': '0.107', 'Smooth muscle cells': '5.8', 'Adipocytes': '2.1', 'Melanocytes': '0.335', 'Fibroblasts': '6.5', 'Peritubular cells': '0.210', 'Endometrial stromal cells': '27.7', 'Ovarian stromal cells': '0.7', 'Undifferentiated cells': '101.6', 'T-cells': '2.9', 'B-cells': '4.4', 'Plasma cells': '6.1', 'Nk-cells': '0.0', 'Granulocytes': '8.4', 'Monocytes': '0.0', 'Macrophages': '6.0', 'Hofbauer cells': '4.3', 'Kupffer cells': '1.0', 'Dendritic cells': '5.9', 'Langerhans cells': '0.304', 'Erythroid cells': '0.036', 'Adipocytes (Subcutaneous)': '-0.081', 'Adipocytes (Visceral)': '-0.209', 'Breast glandular cells (progenitors)': '0.538', 'Adipocytes (Breast)': '-0.689', 'Colon enterocytes': '0.790', 'Colon enteroendocrine cells': '0.112', 'Enteric glia cells': '-0.048', 'Mitotic cells (Colon)': '0.299', 'Mitotic cells (Heart)': '0.120', 'Podocytes': '-0.118', 'Ascending Loop of Henle cells': '0.475', 'Intercalated cells': '0.212', 'Cholangiocyte': '0.090', 'NK-cells (Liver)': '-0.005', 'Respiratory ciliated cells': '-0.012', 'Mitotic cells (Lung)': '0.071', 'NK-cells (Lung)': '-0.266', 'B-cells (Lung)': '-0.296', 'Alpha cells': '0.270', 'Beta cells': '0.152', 'Prostate glandular cells': '0.764', 'Prostate basal glandular cells': '0.540', 'Urothelial cells': '0.205', 'Keratinocyte (other)': '0.510', 'Keratinocyte (granular)': '0.055', 'Hair cortex cells': '0.080', 'Inner root sheath cells': '0.131', 'Outer root sheath cells': '0.175', 'Sebaceous gland cells': '0.156', 'Eccrine sweat gland cells': '-0.207', 'Adipocytes (Skin)': '-0.244', 'Mitotic cells (Skin)': '0.442', 'Parietal cells': '0.654', 'Chief cells': '0.649', 'Gastric mucous cells': '0.781', 'Gastric enteroendocrine cells': '0.590', 'Mitotic cells (Stomach)': '0.445', 'Parafollicular cells': '0.173', 'Thyroid glandular cells': '0.865', 'Mitotic cells (Thyroid)': '-0.081', 'Adrenal cortex cells': '0.051', 'Adrenal medulla cells': '0.087', 'Mitotic cells (Adrenal gland)': '0.072', 'Minor salivary glandular cells': '0.371', 'Minor salivary gland ductal cells': '-0.142', 'Minor salivary gland basal cells': '0.582', 'Mitotic cells (Minor salivary gland)': '0.567', 'Adipocytes (Minor salivary gland)': '0.050', 'Somatotropes': '0.121', 'Lactotropes': '0.322', 'Gonadotropes': '0.330', 'Corticotropes': '0.180', 'Thyrotropes': '0.496', 'Undifferentiated cells (Pituitary gland)': '-0.108', 'Mitotic cells (Spleen)': '-0.228', 'Platelets': '-0.050', 'Erythrocytes': '-0.158', 'Hematopoietic stem cells': '-0.211', 'B-cells (Spleen)': '0.266', 'NK-cells (Spleen)': '0.309', 'Amygdala excitatory': '1.0', 'Cerebellar inhibitory': '0.9', 'Cge interneuron': '0.7', 'Deep-layer corticothalamic and 6b': '1.5', 'Deep-layer intratelencephalic': '0.7', 'Deep-layer near-projecting': '0.7', 'Eccentric medium spiny neuron': '0.6', 'Hippocampal ca1-3': '1.9', 'Hippocampal ca4': '1.2', 'Hippocampal dentate gyrus': '1.1', 'Lamp5-lhx6 and chandelier': '0.5', 'Lower rhombic lip': '0.8', 'Mammillary body': '0.6', 'Medium spiny neuron': '0.7', 'Mge interneuron': '1.7', 'Midbrain-derived inhibitory': '0.7', 'Miscellaneous': '0.9', 'Splatter': '3.8', 'Thalamic excitatory': '0.5', 'Upper rhombic lip': '0.8', 'Upper-layer intratelencephalic': '0.6', 'Astrocyte': '4.4', 'Bergmann glia': '0.2', 'Central nervous system macrophage': '0.6', 'Choroid plexus epithelial cell': '52.1', 'Committed oligodendrocyte precursor': '41.5', 'Ependymal cell': '4.8', 'Oligodendrocyte': '53.1', 'Oligodendrocyte precursor cell': '2.4', 'Endothelial cell': '0.7', 'Pericyte': '0.3', 'Vascular associated smooth muscle cell': '0.0', 'Fibroblast': '17.4', 'Leukocyte': '1.1', 'Basophil': '0.0', 'Eosinophil': '0.0', 'Neutrophil': '0.0', 'Classical monocyte': '0.0', 'Non-classical monocyte': '0.0', 'Intermediate monocyte': '0.0', 'T-reg': '2.3', 'GdT-cell': '0.0', 'MAIT T-cell': '0.0', 'Memory CD4 T-cell': '0.0', 'Naive CD4 T-cell': '0.1', 'Memory CD8 T-cell': '0.2', 'Naive CD8 T-cell': '0.3', 'Memory B-cell': '0.0', 'Naive B-cell': '0.1', 'Plasmacytoid DC': '46.6', 'Myeloid DC': '8.5', 'NK-cell': '0.1', 'Total PBMC': '0.7', 'Vd2 gdTCR': '0.0', 'Memory CD4 T-cell Th1\\/Th17': '0.1', 'Memory CD4 T-cell Th17': '0.2', 'Memory CD4 T-cell Th2': '2.9', 'Non-Vd2 gdTCR': '0.1', 'Memory CD4 T-cell Th1': '0.3', 'Memory CD4 T-cell TFH': '0.5', 'Terminal effector memory CD4 T-cell': '0.0', 'Central memory CD8 T-cell': '4.8', 'Effector memory CD8 T-cell': '0.0', 'Terminal effector memory CD8 T-cell': '0.6', 'Non-switched memory B-cell': '0.0', 'Plasmablast': '3.3', 'Switched memory B-cell': '0.0', 'Exhausted memory B-cell': '0.7', 'Progenitor cell': '2.3', 'Memory T-reg': '1.3', 'Naive CD4 T-cell activated': '0.3', 'Naive CD8 T-cell activated': '0.6', 'Naive T-reg': '0.1'}
1O6S, 2O72, 2OMT, 2OMU, 2OMV, 2OMX, 2OMY, 2OMZ, 3FF7, 3FF8, 3L6X, 3L6Y, 4ZT1, 4ZTE, 6CXY, 6OLE, 6OLF, 6OLG, 6VEL, 7STZ, 8H62
{'Adipose Tissue': 1.2125261088039867, 'Adrenal Gland': 0.1914223992248062, 'Bladder': 39.2033519047619, 'Blood': 1.340954264800861, 'Blood Vessel': 0.3121561692883895, 'Brain': 0.8550442199091597, 'Breast': 38.54918344226579, 'Cervix Uteri': 23.539115789473684, 'Colon': 43.41292142490372, 'Esophagus': 53.97513367404844, 'Fallopian Tube': 14.900277777777776, 'Heart': 0.119140469221835, 'Kidney': 25.040449438202245, 'Liver': 26.60802654867257, 'Lung': 35.447986366782004, 'Muscle': 0.1378936151930261, 'Nerve': 17.518468982229404, 'Ovary': 3.6515122222222223, 'Pancreas': 56.89676829268293, 'Pituitary': 24.68741660777385, 'Prostate': 61.279967346938776, 'Salivary Gland': 92.01685185185184, 'Skin': 79.77571720232172, 'Small Intestine': 71.7519320855615, 'Spleen': 10.061029045643156, 'Stomach': 58.07813805013927, 'Testis': 0.8144204986149585, 'Thyroid': 135.176797856049, 'Uterus': 1.442593943661972, 'Vagina': 86.52345512820513}
HECW2
MASSAREHLLFVRRRNPQMRYTLSPENLQSLAAQSSMPENMTLQRANSDTDLVTSESRSSLTASMYEYTLGQAQNLIIFWDIKEEVDPSDWIGLYHIDENSPANFWDSKNRGVTGTQKGQIVWRIEPGPYFMEPEIKICFKYYHGISGALRATTPCITVKNPAVMMGAEGMEGGASGNLHSRKLVSFTLSDLRAVGLKKGMFFNPDPYLKMSIQPGKKSSFPTCAHHGQERRSTIISNTTNPIWHREKYSFFALLTDVLEIEIKDKFAKSRPIIKRFLGKLTIPVQRLLERQAIGDQMLSYNLGRRLPADHVSGYLQFKVEVTSSVHEDASPEAVGTILGVNSVNGDLGSPSDDEDMPGSHHDSQVCSNGPVSEDSAADGTPKHSFRTSSTLEIDTEELTSTSSRTSPPRGRQDSLNDYLDAIEHNGHSRPGTATCSERSMGASPKLRSSFPTDTRLNAMLHIDSDEEDHEFQQDLGYPSSLEEEGGLIMFSRASRADDGSLTSQTKLEDNPVENEEASTHEAASFEDKPENLPELAESSLPAGPAPEEGEGGPEPQPSADQGSAELCGSQEVDQPTSGADTGTSDASGGSRRAVSETESLDQGSEPSQVSSETEPSDPARTESVSEASTRPEGESDLECADSSCNESVTTQLSSVDTRCSSLESARFPETPAFSSQEEEDGACAAEPTSSGPAEGSQESVCTAGSLPVVQVPSGEDEGPGAESATVPDQEELGEVWQRRGSLEGAAAAAESPPQEEGSAGEAQGTCEGATAQEEGATGGSQANGHQPLRSLPSVRQDVSRYQRVDEALPPNWEARIDSHGRIFYVDHVNRTTTWQRPTAPPAPQVLQRSNSIQQMEQLNRRYQSIRRTMTNERPEENTNAIDGAGEEADFHQASADFRRENILPHSTSRSRITLLLQSPPVKFLISPEFFTVLHSNPSAYRMFTNNTCLKHMITKVRRDTHHFERYQHNRDLVGFLNMFANKQLELPRGWEMKHDHQGKAFFVDHNSRTTTFIDPRLPLQSSRPTSALVHRQHLTRQRSHSAGEVGEDSRHAGPPVLPRPSSTFNTVSRPQYQDMVPVAYNDKIVAFLRQPNIFEILQERQPDLTRNHSLREKIQFIRTEGTPGLVRLSSDADLVMLLSLFEEEIMSYVPPHALLHPSYCQSPRGSPVSSPQNSPGTQRANARAPAPYKRDFEAKLRNFYRKLETKGYGQGPGKLKLIIRRDHLLEDAFNQIMGYSRKDLQRNKLYVTFVGEEGLDYSGPSREFFFLVSRELFNPYYGLFEYSANDTYTVQISPMSAFVDNHHEWFRFSGRILGLALIHQYLLDAFFTRPFYKALLRILCDLSDLEYLDEEFHQSLQWMKDNDIHDILDLTFTVNEEVFGQITERELKPGGANIPVTEKNKKEYIERMVKWRIERGVVQQTESLVRGFYEVVDARLVSVFDARELELVIAGTAEIDLSDWRNNTEYRGGYHDNHIVIRWFWAAVERFNNEQRLRLLQFVTGTSSIPYEGFASLRGSNGPRRFCVEKWGKITALPRAHTCFNRLDLPPYPSFSMLYEKLLTAVEETSTFGLE
Homo sapiens
Cytoplasm, Cytoplasm, cytoskeleton, spindle
Low tissue specificity
{'Ciliated cells': '2.5', 'Basal respiratory cells': '0.1', 'Club cells': '2.5', 'Ionocytes': '0.0', 'Mucus glandular cells': '0.5', 'Serous glandular cells': '3.2', 'Gastric mucus-secreting cells': '0.0', 'Proximal enterocytes': '0.1', 'Paneth cells': '0.0', 'Distal enterocytes': '0.5', 'Intestinal goblet cells': '0.0', 'Exocrine glandular cells': '-0.170', 'Basal prostatic cells': '0.3', 'Prostatic glandular cells': '0.1', 'Breast glandular cells': '-0.205', 'Breast myoepithelial cells': '-0.214', 'Glandular and luminal cells': '0.3', 'Secretory cells': '1.9', 'Basal keratinocytes': '2.4', 'Suprabasal keratinocytes': '5.0', 'Basal squamous epithelial cells': '5.8', 'Squamous epithelial cells': '11.4', 'Alveolar cells type 1': '0.380', 'Alveolar cells type 2': '-0.124', 'Salivary duct cells': '2.4', 'Ductal cells': '0.414', 'Hepatocytes': '0.488', 'Cholangiocytes': '0.0', 'Proximal tubular cells': '0.076', 'Distal tubular cells': '0.0', 'Collecting duct cells': '0.0', 'Mesothelial cells': '-0.093', 'Sertoli cells': '0.470', 'Granulosa cells': '7.5', 'Enteroendocrine cells': '9.2', 'Pancreatic endocrine cells': '1.7', 'Leydig cells': '0.427', 'Excitatory neurons': '320.2', 'Inhibitory neurons': '359.4', 'Cone photoreceptor cells': '0.0', 'Rod photoreceptor cells': '1.1', 'Bipolar cells': '13.3', 'Horizontal cells': '21.4', 'Astrocytes': '12.1', 'Oligodendrocyte precursor cells': '134.4', 'Oligodendrocytes': '428.7', 'Microglial cells': '13.4', 'Muller glia cells': '15.1', 'Schwann cells': '0.230', 'Spermatogonia': '0.697', 'Spermatocytes': '0.465', 'Early spermatids': '-0.177', 'Late spermatids': '-0.432', 'Oocytes': '1.5', 'Cytotrophoblasts': '0.2', 'Syncytiotrophoblasts': '0.3', 'Extravillous trophoblasts': '0.5', 'Endothelial cells': '43.1', 'Lymphatic endothelial cells': '42.2', 'Cardiomyocytes': '0.591', 'Skeletal myocytes': '0.125', 'Smooth muscle cells': '3.2', 'Adipocytes': '51.6', 'Melanocytes': '0.056', 'Fibroblasts': '29.7', 'Peritubular cells': '0.384', 'Endometrial stromal cells': '1.5', 'Ovarian stromal cells': '0.4', 'Undifferentiated cells': '0.0', 'T-cells': '2.0', 'B-cells': '3.7', 'Plasma cells': '3.0', 'Nk-cells': '0.4', 'Granulocytes': '0.7', 'Monocytes': '5.0', 'Macrophages': '1.8', 'Hofbauer cells': '0.3', 'Kupffer cells': '9.9', 'Dendritic cells': '0.0', 'Langerhans cells': '0.131', 'Erythroid cells': '-0.125', 'Adipocytes (Subcutaneous)': '0.159', 'Adipocytes (Visceral)': '0.084', 'Breast glandular cells (progenitors)': '-0.137', 'Adipocytes (Breast)': '0.354', 'Colon enterocytes': '0.109', 'Colon enteroendocrine cells': '0.387', 'Enteric glia cells': '0.304', 'Mitotic cells (Colon)': '0.174', 'Mitotic cells (Heart)': '0.414', 'Podocytes': '0.246', 'Ascending Loop of Henle cells': '0.179', 'Intercalated cells': '0.213', 'Cholangiocyte': '0.327', 'NK-cells (Liver)': '-0.117', 'Respiratory ciliated cells': '-0.035', 'Mitotic cells (Lung)': '-0.077', 'NK-cells (Lung)': '0.401', 'B-cells (Lung)': '-0.028', 'Alpha cells': '0.319', 'Beta cells': '0.193', 'Prostate glandular cells': '0.116', 'Prostate basal glandular cells': '0.290', 'Urothelial cells': '0.222', 'Keratinocyte (other)': '-0.291', 'Keratinocyte (granular)': '-0.284', 'Hair cortex cells': '0.404', 'Inner root sheath cells': '0.434', 'Outer root sheath cells': '0.593', 'Sebaceous gland cells': '0.272', 'Eccrine sweat gland cells': '0.520', 'Adipocytes (Skin)': '0.341', 'Mitotic cells (Skin)': '0.261', 'Parietal cells': '0.099', 'Chief cells': '0.075', 'Gastric mucous cells': '0.148', 'Gastric enteroendocrine cells': '0.246', 'Mitotic cells (Stomach)': '0.219', 'Parafollicular cells': '0.054', 'Thyroid glandular cells': '0.291', 'Mitotic cells (Thyroid)': '0.033', 'Adrenal cortex cells': '0.078', 'Adrenal medulla cells': '0.147', 'Mitotic cells (Adrenal gland)': '-0.009', 'Minor salivary glandular cells': '-0.264', 'Minor salivary gland ductal cells': '-0.195', 'Minor salivary gland basal cells': '0.551', 'Mitotic cells (Minor salivary gland)': '0.575', 'Adipocytes (Minor salivary gland)': '0.202', 'Somatotropes': '0.122', 'Lactotropes': '0.374', 'Gonadotropes': '0.224', 'Corticotropes': '-0.053', 'Thyrotropes': '0.364', 'Undifferentiated cells (Pituitary gland)': '0.159', 'Mitotic cells (Spleen)': '-0.157', 'Platelets': '0.132', 'Erythrocytes': '-0.006', 'Hematopoietic stem cells': '-0.129', 'B-cells (Spleen)': '0.035', 'NK-cells (Spleen)': '0.253', 'Amygdala excitatory': '398.7', 'Cerebellar inhibitory': '391.8', 'Cge interneuron': '436.8', 'Deep-layer corticothalamic and 6b': '682.5', 'Deep-layer intratelencephalic': '480.4', 'Deep-layer near-projecting': '497.4', 'Eccentric medium spiny neuron': '518.3', 'Hippocampal ca1-3': '342.6', 'Hippocampal ca4': '322.8', 'Hippocampal dentate gyrus': '552.0', 'Lamp5-lhx6 and chandelier': '710.9', 'Lower rhombic lip': '450.6', 'Mammillary body': '461.3', 'Medium spiny neuron': '388.6', 'Mge interneuron': '441.2', 'Midbrain-derived inhibitory': '27.6', 'Miscellaneous': '494.0', 'Splatter': '328.3', 'Thalamic excitatory': '351.7', 'Upper rhombic lip': '453.8', 'Upper-layer intratelencephalic': '603.4', 'Astrocyte': '17.3', 'Bergmann glia': '3.6', 'Central nervous system macrophage': '9.6', 'Choroid plexus epithelial cell': '30.9', 'Committed oligodendrocyte precursor': '251.8', 'Ependymal cell': '163.2', 'Oligodendrocyte': '727.3', 'Oligodendrocyte precursor cell': '243.5', 'Endothelial cell': '81.8', 'Pericyte': '8.1', 'Vascular associated smooth muscle cell': '36.9', 'Fibroblast': '42.3', 'Leukocyte': '15.5', 'Basophil': '0.8', 'Eosinophil': '0.8', 'Neutrophil': '21.3', 'Classical monocyte': '0.2', 'Non-classical monocyte': '2.0', 'Intermediate monocyte': '3.5', 'T-reg': '0.2', 'GdT-cell': '0.0', 'MAIT T-cell': '0.2', 'Memory CD4 T-cell': '0.0', 'Naive CD4 T-cell': '0.1', 'Memory CD8 T-cell': '0.0', 'Naive CD8 T-cell': '0.0', 'Memory B-cell': '0.4', 'Naive B-cell': '0.4', 'Plasmacytoid DC': '0.2', 'Myeloid DC': '1.0', 'NK-cell': '0.0', 'Total PBMC': '0.8', 'Vd2 gdTCR': '0.2', 'Memory CD4 T-cell Th1\\/Th17': '0.1', 'Memory CD4 T-cell Th17': '0.2', 'Memory CD4 T-cell Th2': '0.4', 'Non-Vd2 gdTCR': '0.3', 'Memory CD4 T-cell Th1': '0.1', 'Memory CD4 T-cell TFH': '0.3', 'Terminal effector memory CD4 T-cell': '0.1', 'Central memory CD8 T-cell': '0.2', 'Effector memory CD8 T-cell': '0.3', 'Terminal effector memory CD8 T-cell': '0.2', 'Non-switched memory B-cell': '0.2', 'Plasmablast': '0.3', 'Switched memory B-cell': '0.4', 'Exhausted memory B-cell': '0.3', 'Progenitor cell': '0.2', 'Memory T-reg': '0.8', 'Naive CD4 T-cell activated': '5.5', 'Naive CD8 T-cell activated': '1.8', 'Naive T-reg': '0.7'}
2LFE
{'Adipose Tissue': 3.680218853820598, 'Adrenal Gland': 1.8355627906976744, 'Bladder': 0.8448619047619048, 'Blood': 1.4191076953713673, 'Blood Vessel': 2.275656059925094, 'Brain': 4.517491218773656, 'Breast': 3.451143790849674, 'Cervix Uteri': 1.9485526315789472, 'Colon': 0.6536988960205392, 'Esophagus': 1.4922570934256054, 'Fallopian Tube': 1.2434555555555555, 'Heart': 3.034834030197445, 'Kidney': 1.4114966292134832, 'Liver': 0.8818253097345132, 'Lung': 17.315515570934256, 'Muscle': 0.3550280946450809, 'Nerve': 2.1410294022617125, 'Ovary': 0.7675848888888889, 'Pancreas': 0.4490132317073171, 'Pituitary': 2.886590106007067, 'Prostate': 0.9256834693877553, 'Salivary Gland': 1.1903524691358025, 'Skin': 1.4106940298507462, 'Small Intestine': 1.2177085561497327, 'Spleen': 8.482506224066391, 'Stomach': 0.7660788300835654, 'Testis': 3.190506925207756, 'Thyroid': 7.12176110260337, 'Uterus': 1.627284718309859, 'Vagina': 1.831648076923077}
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null
Component of an E-cadherin/ catenin adhesion complex composed of at least E-cadherin/CDH1, beta-catenin/CTNNB1 or gamma-catenin/JUP, and potentially alpha-catenin/CTNNA1. Forms a ternary complex composed of ADAM10, CADH1 and EPHA4,
null
null
KLRG1, SPEF1, DLGAP5, AJAP1, RAPGEF2, RAB8B, PIP5K1C, PKP2, TRPV4, CTNNB1, CAV1, DDR1, TBC1D2, CTNNA1, JUP, CTNND1, PSEN1, LIMA1, CDH1, JUP, ADAM10, CADH1 , EPHA4,
null
null
null
null
Homodimer
null
79.91949
0.474025
60.550261
0.601737
177
P12830
Q9UKT4
null
degron_data
CDH1
MGPWSRSLSALLLLLQVSSWLCQEPEPCHPGFDAESYTFTVPRRHLERGRVLGRVNFEDCTGRQRTAYFSLDTRFKVGTDGVITVKRPLRFHNPQIHFLVYAWDSTYRKFSTKVTLNTVGHHHRPPPHQASVSGIQAELLTFPNSSPGLRRQKRDWVIPPISCPENEKGPFPKNLVQIKSNKDKEGKVFYSITGQGADTPPVGVFIIERETGWLKVTEPLDRERIATYTLFSHAVSSNGNAVEDPMEILITVTDQNDNKPEFTQEVFKGSVMEGALPGTSVMEVTATDADDDVNTYNAAIAYTILSQDPELPDKNMFTINRNTGVISVVTTGLDRESFPTYTLVVQAADLQGEGLSTTATAVITVTDTNDNPPIFNPTTYKGQVPENEANVVITTLKVTDADAPNTPAWEAVYTILNDDGGQFVVTTNPVNNDGILKTAKGLDFEAKQQYILHVAVTNVVPFEVSLTTSTATVTVDVLDVNEAPIFVPPEKRVEVSEDFGVGQEITSYTAQEPDTFMEQKITYRIWRDTANWLEINPDTGAISTRAELDREDFEHVKNSTYTALIIATDNGSPVATGTGTLLLILSDVNDNAPIPEPRTIFFCERNPKPQVINIIDADLPPNTSPFTAELTHGASANWTIQYNDPTQESIILKPKMALEVGDYKINLKLMDNQNKDQVTTLEVSVCDCEGAAGVCRKAQPVEAGLQIPAILGILGGILALLILILLLLLFLRRRAVVKEPLLPPEDDTRDNVYYYDEEGGGEEDQDFDLSQLHRGLDARPEVTRNDVAPTLMSVPRYLPRPANPDEIGNFIDENLKAADTDPTAPPYDSLLVFDYEGSGSEAASLSSLNSSESDKDQDYDYLNEWGNRFKKLADMYGGGEDD
Homo sapiens
Cell junction, adherens junction, Cell membrane, Endosome, Golgi apparatus, trans-Golgi network, Cytoplasm, Cell junction, desmosome
Tissue enhanced (parathyroid)
{'Ciliated cells': '119.1', 'Basal respiratory cells': '71.1', 'Club cells': '97.3', 'Ionocytes': '81.0', 'Mucus glandular cells': '155.0', 'Serous glandular cells': '67.8', 'Gastric mucus-secreting cells': '133.2', 'Proximal enterocytes': '140.9', 'Paneth cells': '125.1', 'Distal enterocytes': '307.5', 'Intestinal goblet cells': '173.5', 'Exocrine glandular cells': '-0.605', 'Basal prostatic cells': '68.3', 'Prostatic glandular cells': '186.7', 'Breast glandular cells': '0.773', 'Breast myoepithelial cells': '0.700', 'Glandular and luminal cells': '313.0', 'Secretory cells': '82.3', 'Basal keratinocytes': '102.5', 'Suprabasal keratinocytes': '162.6', 'Basal squamous epithelial cells': '51.0', 'Squamous epithelial cells': '106.9', 'Alveolar cells type 1': '0.437', 'Alveolar cells type 2': '0.706', 'Salivary duct cells': '95.9', 'Ductal cells': '0.541', 'Hepatocytes': '0.600', 'Cholangiocytes': '129.7', 'Proximal tubular cells': '0.042', 'Distal tubular cells': '0.0', 'Collecting duct cells': '143.9', 'Mesothelial cells': '0.799', 'Sertoli cells': '0.252', 'Granulosa cells': '12.9', 'Enteroendocrine cells': '92.4', 'Pancreatic endocrine cells': '78.1', 'Leydig cells': '0.264', 'Excitatory neurons': '0.7', 'Inhibitory neurons': '1.3', 'Cone photoreceptor cells': '0.0', 'Rod photoreceptor cells': '0.0', 'Bipolar cells': '0.2', 'Horizontal cells': '0.6', 'Astrocytes': '0.6', 'Oligodendrocyte precursor cells': '0.5', 'Oligodendrocytes': '29.9', 'Microglial cells': '0.9', 'Muller glia cells': '0.1', 'Schwann cells': '0.131', 'Spermatogonia': '0.392', 'Spermatocytes': '0.193', 'Early spermatids': '-0.217', 'Late spermatids': '-0.290', 'Oocytes': '16.9', 'Cytotrophoblasts': '119.2', 'Syncytiotrophoblasts': '45.0', 'Extravillous trophoblasts': '24.9', 'Endothelial cells': '6.1', 'Lymphatic endothelial cells': '0.4', 'Cardiomyocytes': '0.135', 'Skeletal myocytes': '0.107', 'Smooth muscle cells': '5.8', 'Adipocytes': '2.1', 'Melanocytes': '0.335', 'Fibroblasts': '6.5', 'Peritubular cells': '0.210', 'Endometrial stromal cells': '27.7', 'Ovarian stromal cells': '0.7', 'Undifferentiated cells': '101.6', 'T-cells': '2.9', 'B-cells': '4.4', 'Plasma cells': '6.1', 'Nk-cells': '0.0', 'Granulocytes': '8.4', 'Monocytes': '0.0', 'Macrophages': '6.0', 'Hofbauer cells': '4.3', 'Kupffer cells': '1.0', 'Dendritic cells': '5.9', 'Langerhans cells': '0.304', 'Erythroid cells': '0.036', 'Adipocytes (Subcutaneous)': '-0.081', 'Adipocytes (Visceral)': '-0.209', 'Breast glandular cells (progenitors)': '0.538', 'Adipocytes (Breast)': '-0.689', 'Colon enterocytes': '0.790', 'Colon enteroendocrine cells': '0.112', 'Enteric glia cells': '-0.048', 'Mitotic cells (Colon)': '0.299', 'Mitotic cells (Heart)': '0.120', 'Podocytes': '-0.118', 'Ascending Loop of Henle cells': '0.475', 'Intercalated cells': '0.212', 'Cholangiocyte': '0.090', 'NK-cells (Liver)': '-0.005', 'Respiratory ciliated cells': '-0.012', 'Mitotic cells (Lung)': '0.071', 'NK-cells (Lung)': '-0.266', 'B-cells (Lung)': '-0.296', 'Alpha cells': '0.270', 'Beta cells': '0.152', 'Prostate glandular cells': '0.764', 'Prostate basal glandular cells': '0.540', 'Urothelial cells': '0.205', 'Keratinocyte (other)': '0.510', 'Keratinocyte (granular)': '0.055', 'Hair cortex cells': '0.080', 'Inner root sheath cells': '0.131', 'Outer root sheath cells': '0.175', 'Sebaceous gland cells': '0.156', 'Eccrine sweat gland cells': '-0.207', 'Adipocytes (Skin)': '-0.244', 'Mitotic cells (Skin)': '0.442', 'Parietal cells': '0.654', 'Chief cells': '0.649', 'Gastric mucous cells': '0.781', 'Gastric enteroendocrine cells': '0.590', 'Mitotic cells (Stomach)': '0.445', 'Parafollicular cells': '0.173', 'Thyroid glandular cells': '0.865', 'Mitotic cells (Thyroid)': '-0.081', 'Adrenal cortex cells': '0.051', 'Adrenal medulla cells': '0.087', 'Mitotic cells (Adrenal gland)': '0.072', 'Minor salivary glandular cells': '0.371', 'Minor salivary gland ductal cells': '-0.142', 'Minor salivary gland basal cells': '0.582', 'Mitotic cells (Minor salivary gland)': '0.567', 'Adipocytes (Minor salivary gland)': '0.050', 'Somatotropes': '0.121', 'Lactotropes': '0.322', 'Gonadotropes': '0.330', 'Corticotropes': '0.180', 'Thyrotropes': '0.496', 'Undifferentiated cells (Pituitary gland)': '-0.108', 'Mitotic cells (Spleen)': '-0.228', 'Platelets': '-0.050', 'Erythrocytes': '-0.158', 'Hematopoietic stem cells': '-0.211', 'B-cells (Spleen)': '0.266', 'NK-cells (Spleen)': '0.309', 'Amygdala excitatory': '1.0', 'Cerebellar inhibitory': '0.9', 'Cge interneuron': '0.7', 'Deep-layer corticothalamic and 6b': '1.5', 'Deep-layer intratelencephalic': '0.7', 'Deep-layer near-projecting': '0.7', 'Eccentric medium spiny neuron': '0.6', 'Hippocampal ca1-3': '1.9', 'Hippocampal ca4': '1.2', 'Hippocampal dentate gyrus': '1.1', 'Lamp5-lhx6 and chandelier': '0.5', 'Lower rhombic lip': '0.8', 'Mammillary body': '0.6', 'Medium spiny neuron': '0.7', 'Mge interneuron': '1.7', 'Midbrain-derived inhibitory': '0.7', 'Miscellaneous': '0.9', 'Splatter': '3.8', 'Thalamic excitatory': '0.5', 'Upper rhombic lip': '0.8', 'Upper-layer intratelencephalic': '0.6', 'Astrocyte': '4.4', 'Bergmann glia': '0.2', 'Central nervous system macrophage': '0.6', 'Choroid plexus epithelial cell': '52.1', 'Committed oligodendrocyte precursor': '41.5', 'Ependymal cell': '4.8', 'Oligodendrocyte': '53.1', 'Oligodendrocyte precursor cell': '2.4', 'Endothelial cell': '0.7', 'Pericyte': '0.3', 'Vascular associated smooth muscle cell': '0.0', 'Fibroblast': '17.4', 'Leukocyte': '1.1', 'Basophil': '0.0', 'Eosinophil': '0.0', 'Neutrophil': '0.0', 'Classical monocyte': '0.0', 'Non-classical monocyte': '0.0', 'Intermediate monocyte': '0.0', 'T-reg': '2.3', 'GdT-cell': '0.0', 'MAIT T-cell': '0.0', 'Memory CD4 T-cell': '0.0', 'Naive CD4 T-cell': '0.1', 'Memory CD8 T-cell': '0.2', 'Naive CD8 T-cell': '0.3', 'Memory B-cell': '0.0', 'Naive B-cell': '0.1', 'Plasmacytoid DC': '46.6', 'Myeloid DC': '8.5', 'NK-cell': '0.1', 'Total PBMC': '0.7', 'Vd2 gdTCR': '0.0', 'Memory CD4 T-cell Th1\\/Th17': '0.1', 'Memory CD4 T-cell Th17': '0.2', 'Memory CD4 T-cell Th2': '2.9', 'Non-Vd2 gdTCR': '0.1', 'Memory CD4 T-cell Th1': '0.3', 'Memory CD4 T-cell TFH': '0.5', 'Terminal effector memory CD4 T-cell': '0.0', 'Central memory CD8 T-cell': '4.8', 'Effector memory CD8 T-cell': '0.0', 'Terminal effector memory CD8 T-cell': '0.6', 'Non-switched memory B-cell': '0.0', 'Plasmablast': '3.3', 'Switched memory B-cell': '0.0', 'Exhausted memory B-cell': '0.7', 'Progenitor cell': '2.3', 'Memory T-reg': '1.3', 'Naive CD4 T-cell activated': '0.3', 'Naive CD8 T-cell activated': '0.6', 'Naive T-reg': '0.1'}
1O6S, 2O72, 2OMT, 2OMU, 2OMV, 2OMX, 2OMY, 2OMZ, 3FF7, 3FF8, 3L6X, 3L6Y, 4ZT1, 4ZTE, 6CXY, 6OLE, 6OLF, 6OLG, 6VEL, 7STZ, 8H62
{'Adipose Tissue': 1.2125261088039867, 'Adrenal Gland': 0.1914223992248062, 'Bladder': 39.2033519047619, 'Blood': 1.340954264800861, 'Blood Vessel': 0.3121561692883895, 'Brain': 0.8550442199091597, 'Breast': 38.54918344226579, 'Cervix Uteri': 23.539115789473684, 'Colon': 43.41292142490372, 'Esophagus': 53.97513367404844, 'Fallopian Tube': 14.900277777777776, 'Heart': 0.119140469221835, 'Kidney': 25.040449438202245, 'Liver': 26.60802654867257, 'Lung': 35.447986366782004, 'Muscle': 0.1378936151930261, 'Nerve': 17.518468982229404, 'Ovary': 3.6515122222222223, 'Pancreas': 56.89676829268293, 'Pituitary': 24.68741660777385, 'Prostate': 61.279967346938776, 'Salivary Gland': 92.01685185185184, 'Skin': 79.77571720232172, 'Small Intestine': 71.7519320855615, 'Spleen': 10.061029045643156, 'Stomach': 58.07813805013927, 'Testis': 0.8144204986149585, 'Thyroid': 135.176797856049, 'Uterus': 1.442593943661972, 'Vagina': 86.52345512820513}
FBXO5
MSRRPCSCALRPPRCSCSASPSAVTAAGRPRPSDSCKEESSTLSVKMKCDFNCNHVHSGLKLVKPDDIGRLVSYTPAYLEGSCKDCIKDYERLSCIGSPIVSPRIVQLETESKRLHNKENQHVQQTLNSTNEIEALETSRLYEDSGYSSFSLQSGLSEHEEGSLLEENFGDSLQSCLLQIQSPDQYPNKNLLPVLHFEKVVCSTLKKNAKRNPKVDREMLKEIIARGNFRLQNIIGRKMGLECVDILSELFRRGLRHVLATILAQLSDMDLINVSKVSTTWKKILEDDKGAFQLYSKAIQRVTENNNKFSPHASTREYVMFRTPLASVQKSAAQTSLKKDAQTKLSNQGDQKGSTYSRHNEFSEVAKTLKKNESLKACIRCNSPAKYDCYLQRATCKREGCGFDYCTKCLCNYHTTKDCSDGKLLKASCKIGPLPGTKKSKKNLRRL
Homo sapiens
Nucleus, Cytoplasm, Cytoplasm, cytoskeleton, spindle
Group enriched (bone marrow, lymphoid tissue)
{'Ciliated cells': '1.9', 'Basal respiratory cells': '4.0', 'Club cells': '2.7', 'Ionocytes': '1.1', 'Mucus glandular cells': '5.0', 'Serous glandular cells': '2.1', 'Gastric mucus-secreting cells': '11.2', 'Proximal enterocytes': '1.0', 'Paneth cells': '0.6', 'Distal enterocytes': '1.4', 'Intestinal goblet cells': '4.4', 'Exocrine glandular cells': '-0.567', 'Basal prostatic cells': '4.4', 'Prostatic glandular cells': '6.0', 'Breast glandular cells': '0.446', 'Breast myoepithelial cells': '0.370', 'Glandular and luminal cells': '3.7', 'Secretory cells': '5.8', 'Basal keratinocytes': '10.4', 'Suprabasal keratinocytes': '5.2', 'Basal squamous epithelial cells': '6.6', 'Squamous epithelial cells': '9.2', 'Alveolar cells type 1': '-0.006', 'Alveolar cells type 2': '-0.175', 'Salivary duct cells': '6.9', 'Ductal cells': '0.643', 'Hepatocytes': '0.330', 'Cholangiocytes': '1.9', 'Proximal tubular cells': '0.165', 'Distal tubular cells': '0.0', 'Collecting duct cells': '1.9', 'Mesothelial cells': '0.352', 'Sertoli cells': '0.400', 'Granulosa cells': '10.8', 'Enteroendocrine cells': '2.1', 'Pancreatic endocrine cells': '17.0', 'Leydig cells': '0.489', 'Excitatory neurons': '1.0', 'Inhibitory neurons': '0.9', 'Cone photoreceptor cells': '3.4', 'Rod photoreceptor cells': '3.0', 'Bipolar cells': '2.6', 'Horizontal cells': '1.9', 'Astrocytes': '1.2', 'Oligodendrocyte precursor cells': '1.4', 'Oligodendrocytes': '1.9', 'Microglial cells': '1.8', 'Muller glia cells': '4.4', 'Schwann cells': '0.153', 'Spermatogonia': '0.641', 'Spermatocytes': '0.629', 'Early spermatids': '-0.164', 'Late spermatids': '-0.476', 'Oocytes': '26.5', 'Cytotrophoblasts': '16.5', 'Syncytiotrophoblasts': '5.3', 'Extravillous trophoblasts': '31.2', 'Endothelial cells': '6.2', 'Lymphatic endothelial cells': '6.2', 'Cardiomyocytes': '0.309', 'Skeletal myocytes': '-0.172', 'Smooth muscle cells': '6.6', 'Adipocytes': '6.0', 'Melanocytes': '0.213', 'Fibroblasts': '8.4', 'Peritubular cells': '0.325', 'Endometrial stromal cells': '10.1', 'Ovarian stromal cells': '5.3', 'Undifferentiated cells': '12.7', 'T-cells': '8.3', 'B-cells': '7.8', 'Plasma cells': '24.8', 'Nk-cells': '8.9', 'Granulocytes': '3.3', 'Monocytes': '8.9', 'Macrophages': '6.3', 'Hofbauer cells': '6.2', 'Kupffer cells': '2.1', 'Dendritic cells': '20.8', 'Langerhans cells': '0.227', 'Erythroid cells': '-0.031', 'Adipocytes (Subcutaneous)': '-0.111', 'Adipocytes (Visceral)': '-0.248', 'Breast glandular cells (progenitors)': '0.433', 'Adipocytes (Breast)': '-0.346', 'Colon enterocytes': '0.106', 'Colon enteroendocrine cells': '0.164', 'Enteric glia cells': '-0.141', 'Mitotic cells (Colon)': '0.145', 'Mitotic cells (Heart)': '0.476', 'Podocytes': '-0.092', 'Ascending Loop of Henle cells': '0.388', 'Intercalated cells': '-0.067', 'Cholangiocyte': '0.233', 'NK-cells (Liver)': '-0.103', 'Respiratory ciliated cells': '-0.048', 'Mitotic cells (Lung)': '0.204', 'NK-cells (Lung)': '0.145', 'B-cells (Lung)': '0.013', 'Alpha cells': '0.341', 'Beta cells': '0.231', 'Prostate glandular cells': '-0.098', 'Prostate basal glandular cells': '0.340', 'Urothelial cells': '0.323', 'Keratinocyte (other)': '0.237', 'Keratinocyte (granular)': '-0.213', 'Hair cortex cells': '0.006', 'Inner root sheath cells': '0.109', 'Outer root sheath cells': '0.246', 'Sebaceous gland cells': '0.052', 'Eccrine sweat gland cells': '0.067', 'Adipocytes (Skin)': '-0.163', 'Mitotic cells (Skin)': '0.566', 'Parietal cells': '-0.529', 'Chief cells': '-0.433', 'Gastric mucous cells': '-0.133', 'Gastric enteroendocrine cells': '-0.286', 'Mitotic cells (Stomach)': '0.396', 'Parafollicular cells': '0.040', 'Thyroid glandular cells': '0.243', 'Mitotic cells (Thyroid)': '0.048', 'Adrenal cortex cells': '0.354', 'Adrenal medulla cells': '0.029', 'Mitotic cells (Adrenal gland)': '0.484', 'Minor salivary glandular cells': '0.388', 'Minor salivary gland ductal cells': '-0.028', 'Minor salivary gland basal cells': '0.429', 'Mitotic cells (Minor salivary gland)': '0.573', 'Adipocytes (Minor salivary gland)': '0.163', 'Somatotropes': '0.180', 'Lactotropes': '0.144', 'Gonadotropes': '0.021', 'Corticotropes': '-0.155', 'Thyrotropes': '0.090', 'Undifferentiated cells (Pituitary gland)': '0.224', 'Mitotic cells (Spleen)': '0.611', 'Platelets': '0.046', 'Erythrocytes': '0.101', 'Hematopoietic stem cells': '0.046', 'B-cells (Spleen)': '0.151', 'NK-cells (Spleen)': '0.005', 'Amygdala excitatory': '1.5', 'Cerebellar inhibitory': '1.1', 'Cge interneuron': '1.4', 'Deep-layer corticothalamic and 6b': '1.3', 'Deep-layer intratelencephalic': '1.3', 'Deep-layer near-projecting': '1.5', 'Eccentric medium spiny neuron': '2.7', 'Hippocampal ca1-3': '1.8', 'Hippocampal ca4': '1.2', 'Hippocampal dentate gyrus': '1.1', 'Lamp5-lhx6 and chandelier': '1.7', 'Lower rhombic lip': '3.2', 'Mammillary body': '1.7', 'Medium spiny neuron': '2.0', 'Mge interneuron': '1.1', 'Midbrain-derived inhibitory': '2.1', 'Miscellaneous': '2.3', 'Splatter': '1.7', 'Thalamic excitatory': '1.9', 'Upper rhombic lip': '4.2', 'Upper-layer intratelencephalic': '1.0', 'Astrocyte': '1.3', 'Bergmann glia': '2.4', 'Central nervous system macrophage': '4.4', 'Choroid plexus epithelial cell': '5.3', 'Committed oligodendrocyte precursor': '2.3', 'Ependymal cell': '0.7', 'Oligodendrocyte': '2.5', 'Oligodendrocyte precursor cell': '2.6', 'Endothelial cell': '3.9', 'Pericyte': '3.5', 'Vascular associated smooth muscle cell': '4.3', 'Fibroblast': '3.3', 'Leukocyte': '4.8', 'Basophil': '3.0', 'Eosinophil': '0.0', 'Neutrophil': '1.1', 'Classical monocyte': '2.9', 'Non-classical monocyte': '5.7', 'Intermediate monocyte': '7.4', 'T-reg': '13.3', 'GdT-cell': '2.8', 'MAIT T-cell': '11.1', 'Memory CD4 T-cell': '4.7', 'Naive CD4 T-cell': '4.1', 'Memory CD8 T-cell': '5.2', 'Naive CD8 T-cell': '4.4', 'Memory B-cell': '5.1', 'Naive B-cell': '10.8', 'Plasmacytoid DC': '16.2', 'Myeloid DC': '7.2', 'NK-cell': '16.3', 'Total PBMC': '11.3', 'Vd2 gdTCR': '16.7', 'Memory CD4 T-cell Th1\\/Th17': '7.0', 'Memory CD4 T-cell Th17': '6.1', 'Memory CD4 T-cell Th2': '6.6', 'Non-Vd2 gdTCR': '16.4', 'Memory CD4 T-cell Th1': '5.6', 'Memory CD4 T-cell TFH': '3.8', 'Terminal effector memory CD4 T-cell': '10.7', 'Central memory CD8 T-cell': '9.3', 'Effector memory CD8 T-cell': '18.8', 'Terminal effector memory CD8 T-cell': '11.7', 'Non-switched memory B-cell': '11.8', 'Plasmablast': '51.5', 'Switched memory B-cell': '11.3', 'Exhausted memory B-cell': '15.9', 'Progenitor cell': '9.2', 'Memory T-reg': '8.4', 'Naive CD4 T-cell activated': '14.4', 'Naive CD8 T-cell activated': '15.0', 'Naive T-reg': '4.7'}
2M6N, 4UI9, 7QE7, 8S4G
{'Adipose Tissue': 4.46368853820598, 'Adrenal Gland': 2.7836837209302323, 'Bladder': 4.683428571428571, 'Blood': 9.41092686759957, 'Blood Vessel': 4.215113108614233, 'Brain': 2.4460707418622256, 'Breast': 4.3349122004357294, 'Cervix Uteri': 7.02178947368421, 'Colon': 4.274623876765083, 'Esophagus': 4.498613910034602, 'Fallopian Tube': 7.098333333333333, 'Heart': 1.276935400696864, 'Kidney': 2.4128337078651687, 'Liver': 2.0997336283185843, 'Lung': 4.993593425605536, 'Muscle': 0.7624879701120797, 'Nerve': 3.966899838449111, 'Ovary': 6.730505555555555, 'Pancreas': 1.520332012195122, 'Pituitary': 4.601763250883392, 'Prostate': 5.342155102040816, 'Salivary Gland': 4.0012839506172835, 'Skin': 9.347860420121616, 'Small Intestine': 6.398553475935829, 'Spleen': 8.300195020746887, 'Stomach': 3.4570470752089135, 'Testis': 5.203008310249308, 'Thyroid': 6.419781010719755, 'Uterus': 7.971521126760563, 'Vagina': 6.534878205128205}
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73.27, 70.36, 72.63, 72.69, 68.11, 66.06, 60.67, 52.64, 44.07, 48.46, 43.79, 36.31]
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0.96, 0.93, 0.54, 0.64, 0.28, 0.54, 0.52, 0.16, 0.51, 0.88, 0.6, 0.4, 0.88, 0.95, 0.33, 0.56, 0.73, 0.39, 0.06, 0.61, 0.75, 0.47, 0.19, 0.87, 0.7, 0.97, 0.94, 0.97]
[44.01, 50.91, 44.11, 46.07, 56.52, 43.83, 44.99, 42.46, 42.65, 46.15, 45.36, 56.44, 54.6, 41.72, 44.18, 41.76, 47.57, 40.18, 40.44, 43.8, 49.34, 41.04, 40.98, 45.42, 40.81, 40.4, 41.15, 39.68, 38.17, 43.23, 41.56, 46.89, 40.74, 37.99, 37.05, 34.31, 38.15, 37.23, 37.85, 35.0, 40.55, 37.07, 37.56, 36.03, 36.47, 37.77, 39.96, 37.04, 34.64, 29.8, 33.16, 35.18, 33.27, 32.53, 32.1, 31.8, 31.09, 35.46, 26.52, 32.46, 32.94, 28.51, 35.53, 30.75, 43.16, 41.65, 35.25, 40.96, 35.4, 36.58, 35.57, 33.98, 30.04, 31.22, 32.12, 30.19, 33.09, 32.36, 35.93, 33.2, 33.12, 29.89, 32.0, 30.82, 33.16, 32.1, 35.22, 36.98, 34.97, 33.4, 31.58, 35.47, 32.86, 29.53, 32.85, 35.76, 30.79, 31.78, 33.82, 31.05, 34.97, 26.99, 35.64, 33.47, 31.28, 33.62, 28.98, 31.7, 29.11, 27.73, 31.6, 28.32, 36.72, 33.04, 38.89, 41.4, 53.88, 52.68, 45.64, 46.93, 45.34, 43.88, 43.21, 40.15, 40.26, 39.03, 41.06, 38.59, 34.33, 33.52, 34.87, 42.68, 38.98, 34.52, 41.45, 39.81, 37.06, 38.95, 37.03, 36.03, 35.77, 40.53, 41.45, 40.63, 53.32, 52.42, 53.23, 42.38, 44.95, 45.13, 40.0, 37.97, 36.23, 37.04, 32.1, 38.53, 34.67, 37.02, 36.29, 37.91, 38.06, 35.69, 33.36, 35.8, 40.13, 36.19, 37.57, 33.75, 36.14, 33.4, 32.85, 37.03, 39.12, 39.06, 36.28, 34.64, 41.22, 38.14, 33.14, 40.06, 39.53, 41.22, 42.87, 43.9, 47.67, 48.18, 55.99, 56.1, 60.18, 62.29, 66.34, 77.03, 78.41, 79.74, 81.33, 82.37, 84.62, 85.39, 86.42, 85.37, 85.78, 85.65, 85.53, 84.08, 85.74, 85.24, 80.78, 74.66, 67.21, 68.01, 68.87, 71.93, 75.56, 74.76, 72.84, 76.54, 78.26, 80.99, 78.61, 82.19, 82.35, 81.55, 80.36, 80.39, 77.45, 76.61, 69.47, 70.73, 72.86, 72.02, 72.57, 68.86, 71.9, 78.71, 79.01, 80.84, 81.17, 82.26, 82.62, 86.08, 86.36, 88.9, 87.98, 89.06, 92.23, 92.21, 92.31, 91.15, 90.25, 91.27, 91.54, 87.63, 85.04, 85.05, 87.72, 90.23, 90.91, 92.07, 93.13, 91.7, 93.11, 93.42, 93.18, 90.81, 92.43, 92.37, 91.21, 90.03, 89.01, 92.35, 92.33, 90.84, 91.9, 91.73, 90.22, 90.88, 91.43, 90.7, 92.09, 92.64, 94.76, 92.35, 92.54, 92.64, 92.02, 90.63, 90.35, 90.86, 90.2, 88.65, 89.87, 90.61, 91.37, 90.66, 92.23, 90.6, 90.87, 90.77, 89.99, 89.7, 88.2, 84.13, 84.22, 83.23, 72.1, 63.82, 59.48, 57.08, 46.14, 50.2, 51.43, 49.03, 48.54, 50.1, 54.59, 52.09, 46.2, 51.85, 50.2, 60.11, 55.02, 55.17, 65.11, 56.07, 62.33, 62.15, 60.85, 57.97, 60.12, 56.58, 47.99, 45.4, 47.73, 50.65, 44.43, 43.57, 47.13, 44.58, 39.0, 42.14, 40.12, 37.31, 39.68, 37.19, 41.84, 38.74, 35.1, 43.32, 35.11, 44.04, 42.56, 46.29, 40.33, 53.96, 50.28, 63.88, 78.44, 80.69, 85.67, 85.86, 86.24, 90.47, 87.11, 87.09, 85.93, 86.29, 85.5, 84.59, 82.13, 79.52, 75.56, 75.23, 80.89, 88.74, 91.9, 91.55, 92.21, 93.05, 91.33, 89.08, 90.13, 89.88, 91.44, 92.18, 93.0, 92.05, 92.66, 88.73, 86.97, 85.0, 86.0, 87.7, 91.16, 93.09, 93.6, 93.65, 88.86, 89.18, 87.53, 87.73, 91.27, 89.88, 92.85, 93.67, 93.47, 92.1, 89.65, 88.15, 88.27, 89.22, 86.86, 90.2, 90.86, 89.08, 83.37, 78.19, 78.08, 76.43, 80.67, 71.99, 58.34, 55.77, 48.84, 47.19, 49.81, 40.28, 44.55, 42.06, 40.21, 44.09, 48.92, 58.9, 57.77, 62.93, 55.64, 63.58, 69.35, 69.69, 67.79, 66.27, 67.76, 67.89, 60.38, 61.07, 62.67, 61.57, 49.49]
[1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 0.97, 1.0, 0.92, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 0.98, 0.85, 0.97, 0.84, 0.97, 0.97, 1.0, 0.98, 0.99, 0.86, 0.99, 0.8, 0.86, 0.81, 0.85, 0.82, 0.83, 0.74, 0.9, 0.8, 0.73, 0.7, 0.63, 0.84, 0.75, 0.83, 0.67, 0.75, 0.82, 0.73, 0.78, 0.87, 0.94, 0.91, 0.95, 0.84, 0.88, 0.94, 0.87, 0.99, 1.0, 0.92, 1.0, 1.0, 0.99, 1.0, 1.0, 0.98, 0.98, 0.81, 0.96, 0.88, 0.83, 0.82, 0.61, 0.79, 0.86, 0.87, 0.85, 1.0, 0.92, 0.96, 0.92, 0.96, 0.98, 0.98, 1.0, 0.99, 1.0, 1.0, 1.0, 1.0, 1.0, 0.93, 1.0, 0.92, 0.97, 0.96, 0.88, 0.78, 0.94, 0.81, 0.99, 0.76, 0.98, 0.75, 0.97, 0.9, 0.9, 0.66, 0.8, 0.85, 0.56, 0.6, 0.67, 0.62, 0.68, 0.64, 0.79, 0.82, 0.76, 0.86, 0.92, 0.85, 1.0, 0.87, 1.0, 0.94, 0.86, 0.9, 0.9, 0.84, 0.89, 0.96, 1.0, 1.0, 0.94, 0.74, 0.84, 0.77, 0.85, 0.97, 0.98, 0.92, 0.99, 1.0, 0.99, 0.99, 1.0, 0.99, 1.0, 1.0, 1.0, 1.0, 0.97, 1.0, 0.98, 1.0, 0.99, 0.82, 0.91, 0.84, 0.69, 0.97, 0.79, 0.89, 0.82, 0.7, 0.73, 0.83, 0.84, 0.7, 0.76, 0.76, 0.98, 0.96, 0.89, 0.83, 0.28, 0.82, 0.36, 0.83, 0.91, 0.31, 0.58, 0.39, 0.45, 0.43, 0.18, 0.24, 0.54, 0.57, 0.31, 0.17, 0.51, 0.45, 0.12, 0.37, 0.82, 0.86, 0.09, 0.69, 0.99, 0.61, 0.62, 0.7, 0.75, 0.43, 0.16, 0.7, 0.64, 0.35, 0.17, 0.57, 0.45, 0.2, 0.49, 0.77, 0.76, 0.28, 0.66, 0.07, 0.54, 0.25, 0.62, 0.76, 0.29, 0.88, 0.4, 0.6, 0.4, 0.8, 0.98, 0.52, 0.98, 0.91, 0.42, 0.38, 0.63, 0.09, 0.12, 0.17, 0.17, 0.34, 0.61, 0.58, 0.53, 0.26, 0.59, 0.6, 0.39, 0.05, 0.25, 0.6, 0.36, 0.0, 0.6, 0.84, 0.32, 0.49, 0.38, 0.29, 0.42, 0.01, 0.07, 0.38, 0.08, 0.19, 0.64, 0.6, 0.33, 0.66, 0.41, 0.22, 0.42, 0.56, 0.02, 0.0, 0.47, 0.37, 0.29, 0.77, 0.45, 0.05, 0.39, 0.53, 0.39, 0.14, 0.42, 0.53, 0.02, 0.39, 0.57, 0.46, 0.28, 0.48, 0.37, 0.51, 0.49, 0.79, 0.67, 0.56, 0.69, 0.96, 0.95, 0.83, 0.68, 0.9, 0.98, 0.84, 0.99, 0.54, 0.83, 0.49, 0.77, 0.74, 0.93, 0.76, 0.66, 0.75, 0.67, 0.81, 0.89, 0.67, 0.8, 0.81, 0.88, 0.75, 0.85, 0.84, 0.96, 0.96, 0.97, 0.98, 1.0, 0.98, 1.0, 1.0, 1.0, 1.0, 0.98, 0.97, 0.97, 0.95, 0.9, 0.88, 0.72, 0.82, 0.69, 0.44, 0.4, 0.73, 0.47, 0.15, 0.22, 0.4, 0.56, 0.27, 0.44, 0.64, 0.75, 0.29, 0.73, 0.97, 0.85, 0.32, 0.37, 0.26, 0.31, 0.49, 0.0, 0.42, 0.7, 0.3, 0.51, 0.0, 0.03, 0.0, 0.36, 0.18, 0.4, 0.48, 0.94, 0.51, 0.27, 0.35, 0.0, 0.34, 0.07, 0.6, 0.36, 0.92, 0.92, 0.28, 0.48, 0.1, 0.26, 0.03, 0.02, 0.15, 0.47, 0.1, 0.33, 0.45, 0.64, 0.3, 0.3, 0.86, 1.0, 0.78, 0.92, 0.24, 0.61, 0.56, 0.93, 0.83, 0.78, 0.57, 0.92, 0.67, 0.91, 0.81, 0.92, 0.89, 0.71, 0.55, 0.71, 0.93, 0.55, 0.35, 0.87, 0.77, 0.27, 0.62, 0.8, 0.79, 0.65, 0.88, 0.94, 0.87]
null
Component of an E-cadherin/ catenin adhesion complex composed of at least E-cadherin/CDH1, beta-catenin/CTNNB1 or gamma-catenin/JUP, and potentially alpha-catenin/CTNNA1. Forms a ternary complex composed of ADAM10, CADH1 and EPHA4,
null
null
KLRG1, SPEF1, DLGAP5, AJAP1, RAPGEF2, RAB8B, PIP5K1C, PKP2, TRPV4, CTNNB1, CAV1, DDR1, TBC1D2, CTNNA1, JUP, CTNND1, PSEN1, LIMA1, CDH1, JUP, ADAM10, CADH1 , EPHA4,
null
null
null
null
Homodimer
null
79.91949
0.474025
59.797673
0.69217
1,776
P12830
Q9ULW0
null
degron_data
CDH1
MGPWSRSLSALLLLLQVSSWLCQEPEPCHPGFDAESYTFTVPRRHLERGRVLGRVNFEDCTGRQRTAYFSLDTRFKVGTDGVITVKRPLRFHNPQIHFLVYAWDSTYRKFSTKVTLNTVGHHHRPPPHQASVSGIQAELLTFPNSSPGLRRQKRDWVIPPISCPENEKGPFPKNLVQIKSNKDKEGKVFYSITGQGADTPPVGVFIIERETGWLKVTEPLDRERIATYTLFSHAVSSNGNAVEDPMEILITVTDQNDNKPEFTQEVFKGSVMEGALPGTSVMEVTATDADDDVNTYNAAIAYTILSQDPELPDKNMFTINRNTGVISVVTTGLDRESFPTYTLVVQAADLQGEGLSTTATAVITVTDTNDNPPIFNPTTYKGQVPENEANVVITTLKVTDADAPNTPAWEAVYTILNDDGGQFVVTTNPVNNDGILKTAKGLDFEAKQQYILHVAVTNVVPFEVSLTTSTATVTVDVLDVNEAPIFVPPEKRVEVSEDFGVGQEITSYTAQEPDTFMEQKITYRIWRDTANWLEINPDTGAISTRAELDREDFEHVKNSTYTALIIATDNGSPVATGTGTLLLILSDVNDNAPIPEPRTIFFCERNPKPQVINIIDADLPPNTSPFTAELTHGASANWTIQYNDPTQESIILKPKMALEVGDYKINLKLMDNQNKDQVTTLEVSVCDCEGAAGVCRKAQPVEAGLQIPAILGILGGILALLILILLLLLFLRRRAVVKEPLLPPEDDTRDNVYYYDEEGGGEEDQDFDLSQLHRGLDARPEVTRNDVAPTLMSVPRYLPRPANPDEIGNFIDENLKAADTDPTAPPYDSLLVFDYEGSGSEAASLSSLNSSESDKDQDYDYLNEWGNRFKKLADMYGGGEDD
Homo sapiens
Cell junction, adherens junction, Cell membrane, Endosome, Golgi apparatus, trans-Golgi network, Cytoplasm, Cell junction, desmosome
Tissue enhanced (parathyroid)
{'Ciliated cells': '119.1', 'Basal respiratory cells': '71.1', 'Club cells': '97.3', 'Ionocytes': '81.0', 'Mucus glandular cells': '155.0', 'Serous glandular cells': '67.8', 'Gastric mucus-secreting cells': '133.2', 'Proximal enterocytes': '140.9', 'Paneth cells': '125.1', 'Distal enterocytes': '307.5', 'Intestinal goblet cells': '173.5', 'Exocrine glandular cells': '-0.605', 'Basal prostatic cells': '68.3', 'Prostatic glandular cells': '186.7', 'Breast glandular cells': '0.773', 'Breast myoepithelial cells': '0.700', 'Glandular and luminal cells': '313.0', 'Secretory cells': '82.3', 'Basal keratinocytes': '102.5', 'Suprabasal keratinocytes': '162.6', 'Basal squamous epithelial cells': '51.0', 'Squamous epithelial cells': '106.9', 'Alveolar cells type 1': '0.437', 'Alveolar cells type 2': '0.706', 'Salivary duct cells': '95.9', 'Ductal cells': '0.541', 'Hepatocytes': '0.600', 'Cholangiocytes': '129.7', 'Proximal tubular cells': '0.042', 'Distal tubular cells': '0.0', 'Collecting duct cells': '143.9', 'Mesothelial cells': '0.799', 'Sertoli cells': '0.252', 'Granulosa cells': '12.9', 'Enteroendocrine cells': '92.4', 'Pancreatic endocrine cells': '78.1', 'Leydig cells': '0.264', 'Excitatory neurons': '0.7', 'Inhibitory neurons': '1.3', 'Cone photoreceptor cells': '0.0', 'Rod photoreceptor cells': '0.0', 'Bipolar cells': '0.2', 'Horizontal cells': '0.6', 'Astrocytes': '0.6', 'Oligodendrocyte precursor cells': '0.5', 'Oligodendrocytes': '29.9', 'Microglial cells': '0.9', 'Muller glia cells': '0.1', 'Schwann cells': '0.131', 'Spermatogonia': '0.392', 'Spermatocytes': '0.193', 'Early spermatids': '-0.217', 'Late spermatids': '-0.290', 'Oocytes': '16.9', 'Cytotrophoblasts': '119.2', 'Syncytiotrophoblasts': '45.0', 'Extravillous trophoblasts': '24.9', 'Endothelial cells': '6.1', 'Lymphatic endothelial cells': '0.4', 'Cardiomyocytes': '0.135', 'Skeletal myocytes': '0.107', 'Smooth muscle cells': '5.8', 'Adipocytes': '2.1', 'Melanocytes': '0.335', 'Fibroblasts': '6.5', 'Peritubular cells': '0.210', 'Endometrial stromal cells': '27.7', 'Ovarian stromal cells': '0.7', 'Undifferentiated cells': '101.6', 'T-cells': '2.9', 'B-cells': '4.4', 'Plasma cells': '6.1', 'Nk-cells': '0.0', 'Granulocytes': '8.4', 'Monocytes': '0.0', 'Macrophages': '6.0', 'Hofbauer cells': '4.3', 'Kupffer cells': '1.0', 'Dendritic cells': '5.9', 'Langerhans cells': '0.304', 'Erythroid cells': '0.036', 'Adipocytes (Subcutaneous)': '-0.081', 'Adipocytes (Visceral)': '-0.209', 'Breast glandular cells (progenitors)': '0.538', 'Adipocytes (Breast)': '-0.689', 'Colon enterocytes': '0.790', 'Colon enteroendocrine cells': '0.112', 'Enteric glia cells': '-0.048', 'Mitotic cells (Colon)': '0.299', 'Mitotic cells (Heart)': '0.120', 'Podocytes': '-0.118', 'Ascending Loop of Henle cells': '0.475', 'Intercalated cells': '0.212', 'Cholangiocyte': '0.090', 'NK-cells (Liver)': '-0.005', 'Respiratory ciliated cells': '-0.012', 'Mitotic cells (Lung)': '0.071', 'NK-cells (Lung)': '-0.266', 'B-cells (Lung)': '-0.296', 'Alpha cells': '0.270', 'Beta cells': '0.152', 'Prostate glandular cells': '0.764', 'Prostate basal glandular cells': '0.540', 'Urothelial cells': '0.205', 'Keratinocyte (other)': '0.510', 'Keratinocyte (granular)': '0.055', 'Hair cortex cells': '0.080', 'Inner root sheath cells': '0.131', 'Outer root sheath cells': '0.175', 'Sebaceous gland cells': '0.156', 'Eccrine sweat gland cells': '-0.207', 'Adipocytes (Skin)': '-0.244', 'Mitotic cells (Skin)': '0.442', 'Parietal cells': '0.654', 'Chief cells': '0.649', 'Gastric mucous cells': '0.781', 'Gastric enteroendocrine cells': '0.590', 'Mitotic cells (Stomach)': '0.445', 'Parafollicular cells': '0.173', 'Thyroid glandular cells': '0.865', 'Mitotic cells (Thyroid)': '-0.081', 'Adrenal cortex cells': '0.051', 'Adrenal medulla cells': '0.087', 'Mitotic cells (Adrenal gland)': '0.072', 'Minor salivary glandular cells': '0.371', 'Minor salivary gland ductal cells': '-0.142', 'Minor salivary gland basal cells': '0.582', 'Mitotic cells (Minor salivary gland)': '0.567', 'Adipocytes (Minor salivary gland)': '0.050', 'Somatotropes': '0.121', 'Lactotropes': '0.322', 'Gonadotropes': '0.330', 'Corticotropes': '0.180', 'Thyrotropes': '0.496', 'Undifferentiated cells (Pituitary gland)': '-0.108', 'Mitotic cells (Spleen)': '-0.228', 'Platelets': '-0.050', 'Erythrocytes': '-0.158', 'Hematopoietic stem cells': '-0.211', 'B-cells (Spleen)': '0.266', 'NK-cells (Spleen)': '0.309', 'Amygdala excitatory': '1.0', 'Cerebellar inhibitory': '0.9', 'Cge interneuron': '0.7', 'Deep-layer corticothalamic and 6b': '1.5', 'Deep-layer intratelencephalic': '0.7', 'Deep-layer near-projecting': '0.7', 'Eccentric medium spiny neuron': '0.6', 'Hippocampal ca1-3': '1.9', 'Hippocampal ca4': '1.2', 'Hippocampal dentate gyrus': '1.1', 'Lamp5-lhx6 and chandelier': '0.5', 'Lower rhombic lip': '0.8', 'Mammillary body': '0.6', 'Medium spiny neuron': '0.7', 'Mge interneuron': '1.7', 'Midbrain-derived inhibitory': '0.7', 'Miscellaneous': '0.9', 'Splatter': '3.8', 'Thalamic excitatory': '0.5', 'Upper rhombic lip': '0.8', 'Upper-layer intratelencephalic': '0.6', 'Astrocyte': '4.4', 'Bergmann glia': '0.2', 'Central nervous system macrophage': '0.6', 'Choroid plexus epithelial cell': '52.1', 'Committed oligodendrocyte precursor': '41.5', 'Ependymal cell': '4.8', 'Oligodendrocyte': '53.1', 'Oligodendrocyte precursor cell': '2.4', 'Endothelial cell': '0.7', 'Pericyte': '0.3', 'Vascular associated smooth muscle cell': '0.0', 'Fibroblast': '17.4', 'Leukocyte': '1.1', 'Basophil': '0.0', 'Eosinophil': '0.0', 'Neutrophil': '0.0', 'Classical monocyte': '0.0', 'Non-classical monocyte': '0.0', 'Intermediate monocyte': '0.0', 'T-reg': '2.3', 'GdT-cell': '0.0', 'MAIT T-cell': '0.0', 'Memory CD4 T-cell': '0.0', 'Naive CD4 T-cell': '0.1', 'Memory CD8 T-cell': '0.2', 'Naive CD8 T-cell': '0.3', 'Memory B-cell': '0.0', 'Naive B-cell': '0.1', 'Plasmacytoid DC': '46.6', 'Myeloid DC': '8.5', 'NK-cell': '0.1', 'Total PBMC': '0.7', 'Vd2 gdTCR': '0.0', 'Memory CD4 T-cell Th1\\/Th17': '0.1', 'Memory CD4 T-cell Th17': '0.2', 'Memory CD4 T-cell Th2': '2.9', 'Non-Vd2 gdTCR': '0.1', 'Memory CD4 T-cell Th1': '0.3', 'Memory CD4 T-cell TFH': '0.5', 'Terminal effector memory CD4 T-cell': '0.0', 'Central memory CD8 T-cell': '4.8', 'Effector memory CD8 T-cell': '0.0', 'Terminal effector memory CD8 T-cell': '0.6', 'Non-switched memory B-cell': '0.0', 'Plasmablast': '3.3', 'Switched memory B-cell': '0.0', 'Exhausted memory B-cell': '0.7', 'Progenitor cell': '2.3', 'Memory T-reg': '1.3', 'Naive CD4 T-cell activated': '0.3', 'Naive CD8 T-cell activated': '0.6', 'Naive T-reg': '0.1'}
1O6S, 2O72, 2OMT, 2OMU, 2OMV, 2OMX, 2OMY, 2OMZ, 3FF7, 3FF8, 3L6X, 3L6Y, 4ZT1, 4ZTE, 6CXY, 6OLE, 6OLF, 6OLG, 6VEL, 7STZ, 8H62
{'Adipose Tissue': 1.2125261088039867, 'Adrenal Gland': 0.1914223992248062, 'Bladder': 39.2033519047619, 'Blood': 1.340954264800861, 'Blood Vessel': 0.3121561692883895, 'Brain': 0.8550442199091597, 'Breast': 38.54918344226579, 'Cervix Uteri': 23.539115789473684, 'Colon': 43.41292142490372, 'Esophagus': 53.97513367404844, 'Fallopian Tube': 14.900277777777776, 'Heart': 0.119140469221835, 'Kidney': 25.040449438202245, 'Liver': 26.60802654867257, 'Lung': 35.447986366782004, 'Muscle': 0.1378936151930261, 'Nerve': 17.518468982229404, 'Ovary': 3.6515122222222223, 'Pancreas': 56.89676829268293, 'Pituitary': 24.68741660777385, 'Prostate': 61.279967346938776, 'Salivary Gland': 92.01685185185184, 'Skin': 79.77571720232172, 'Small Intestine': 71.7519320855615, 'Spleen': 10.061029045643156, 'Stomach': 58.07813805013927, 'Testis': 0.8144204986149585, 'Thyroid': 135.176797856049, 'Uterus': 1.442593943661972, 'Vagina': 86.52345512820513}
TPX2
MSQVKSSYSYDAPSDFINFSSLDDEGDTQNIDSWFEEKANLENKLLGKNGTGGLFQGKTPLRKANLQQAIVTPLKPVDNTYYKEAEKENLVEQSIPSNACSSLEVEAAISRKTPAQPQRRSLRLSAQKDLEQKEKHHVKMKAKRCATPVIIDEILPSKKMKVSNNKKKPEEEGSAHQDTAEKNASSPEKAKGRHTVPCMPPAKQKFLKSTEEQELEKSMKMQQEVVEMRKKNEEFKKLALAGIGQPVKKSVSQVTKSVDFHFRTDERIKQHPKNQEEYKEVNFTSELRKHPSSPARVTKGCTIVKPFNLSQGKKRTFDETVSTYVPLAQQVEDFHKRTPNRYHLRSKKDDINLLPSKSSVTKICRDPQTPVLQTKHRARAVTCKSTAELEAEELEKLQQYKFKARELDPRILEGGPILPKKPPVKPPTEPIGFDLEIEKRIQERESKKKTEDEHFEFHSRPCPTKILEDVVGVPEKKVLPITVPKSPAFALKNRIRMPTKEDEEEDEPVVIKAQPVPHYGVPFKPQIPEARTVEICPFSFDSRDKERQLQKEKKIKELQKGEVPKFKALPLPHFDTINLPEKKVKNVTQIEPFCLETDRRGALKAQTWKHQLEEELRQQKEAACFKARPNTVISQEPFVPKKEKKSVAEGLSGSLVQEPFQLATEKRAKERQELEKRMAEVEAQKAQQLEEARLQEEEQKKEELARLRRELVHKANPIRKYQGLEIKSSDQPLTVPVSPKFSTRFHC
Homo sapiens
Nucleus, Cytoplasm, cytoskeleton, spindle, Cytoplasm, cytoskeleton, spindle pole
Tissue enhanced (bone marrow, lymphoid tissue, testis)
{'Ciliated cells': '3.9', 'Basal respiratory cells': '4.3', 'Club cells': '3.1', 'Ionocytes': '1.5', 'Mucus glandular cells': '2.3', 'Serous glandular cells': '9.1', 'Gastric mucus-secreting cells': '17.7', 'Proximal enterocytes': '0.6', 'Paneth cells': '0.2', 'Distal enterocytes': '1.5', 'Intestinal goblet cells': '8.4', 'Exocrine glandular cells': '-0.291', 'Basal prostatic cells': '0.0', 'Prostatic glandular cells': '0.1', 'Breast glandular cells': '-0.001', 'Breast myoepithelial cells': '0.077', 'Glandular and luminal cells': '8.2', 'Secretory cells': '1.2', 'Basal keratinocytes': '23.4', 'Suprabasal keratinocytes': '10.1', 'Basal squamous epithelial cells': '9.5', 'Squamous epithelial cells': '29.3', 'Alveolar cells type 1': '-0.273', 'Alveolar cells type 2': '0.108', 'Salivary duct cells': '3.3', 'Ductal cells': '0.459', 'Hepatocytes': '0.399', 'Cholangiocytes': '0.0', 'Proximal tubular cells': '0.210', 'Distal tubular cells': '0.0', 'Collecting duct cells': '0.0', 'Mesothelial cells': '-0.020', 'Sertoli cells': '0.087', 'Granulosa cells': '5.8', 'Enteroendocrine cells': '3.0', 'Pancreatic endocrine cells': '10.2', 'Leydig cells': '-0.006', 'Excitatory neurons': '2.8', 'Inhibitory neurons': '0.8', 'Cone photoreceptor cells': '1.7', 'Rod photoreceptor cells': '0.3', 'Bipolar cells': '0.1', 'Horizontal cells': '1.3', 'Astrocytes': '0.0', 'Oligodendrocyte precursor cells': '0.5', 'Oligodendrocytes': '0.5', 'Microglial cells': '0.9', 'Muller glia cells': '0.5', 'Schwann cells': '0.110', 'Spermatogonia': '0.434', 'Spermatocytes': '0.758', 'Early spermatids': '0.474', 'Late spermatids': '0.036', 'Oocytes': '44.1', 'Cytotrophoblasts': '24.7', 'Syncytiotrophoblasts': '6.0', 'Extravillous trophoblasts': '72.9', 'Endothelial cells': '2.6', 'Lymphatic endothelial cells': '0.3', 'Cardiomyocytes': '0.356', 'Skeletal myocytes': '0.094', 'Smooth muscle cells': '5.7', 'Adipocytes': '0.9', 'Melanocytes': '0.546', 'Fibroblasts': '5.1', 'Peritubular cells': '-0.102', 'Endometrial stromal cells': '5.2', 'Ovarian stromal cells': '0.7', 'Undifferentiated cells': '37.3', 'T-cells': '7.0', 'B-cells': '2.9', 'Plasma cells': '38.0', 'Nk-cells': '4.3', 'Granulocytes': '0.3', 'Monocytes': '0.2', 'Macrophages': '7.8', 'Hofbauer cells': '13.9', 'Kupffer cells': '6.7', 'Dendritic cells': '4.1', 'Langerhans cells': '0.193', 'Erythroid cells': '0.031', 'Adipocytes (Subcutaneous)': '-0.118', 'Adipocytes (Visceral)': '-0.072', 'Breast glandular cells (progenitors)': '0.014', 'Adipocytes (Breast)': '0.035', 'Colon enterocytes': '0.357', 'Colon enteroendocrine cells': '-0.045', 'Enteric glia cells': '-0.084', 'Mitotic cells (Colon)': '0.760', 'Mitotic cells (Heart)': '0.815', 'Podocytes': '-0.198', 'Ascending Loop of Henle cells': '0.291', 'Intercalated cells': '-0.151', 'Cholangiocyte': '0.164', 'NK-cells (Liver)': '-0.119', 'Respiratory ciliated cells': '-0.005', 'Mitotic cells (Lung)': '0.940', 'NK-cells (Lung)': '-0.107', 'B-cells (Lung)': '0.042', 'Alpha cells': '0.157', 'Beta cells': '0.041', 'Prostate glandular cells': '-0.172', 'Prostate basal glandular cells': '0.126', 'Urothelial cells': '0.208', 'Keratinocyte (other)': '0.337', 'Keratinocyte (granular)': '-0.050', 'Hair cortex cells': '0.086', 'Inner root sheath cells': '0.224', 'Outer root sheath cells': '0.187', 'Sebaceous gland cells': '0.053', 'Eccrine sweat gland cells': '-0.090', 'Adipocytes (Skin)': '-0.159', 'Mitotic cells (Skin)': '0.880', 'Parietal cells': '0.162', 'Chief cells': '0.119', 'Gastric mucous cells': '0.574', 'Gastric enteroendocrine cells': '0.216', 'Mitotic cells (Stomach)': '0.935', 'Parafollicular cells': '-0.056', 'Thyroid glandular cells': '-0.024', 'Mitotic cells (Thyroid)': '0.725', 'Adrenal cortex cells': '0.462', 'Adrenal medulla cells': '0.057', 'Mitotic cells (Adrenal gland)': '0.873', 'Minor salivary glandular cells': '0.112', 'Minor salivary gland ductal cells': '-0.332', 'Minor salivary gland basal cells': '0.681', 'Mitotic cells (Minor salivary gland)': '0.971', 'Adipocytes (Minor salivary gland)': '0.171', 'Somatotropes': '-0.354', 'Lactotropes': '-0.286', 'Gonadotropes': '-0.045', 'Corticotropes': '-0.112', 'Thyrotropes': '-0.080', 'Undifferentiated cells (Pituitary gland)': '0.459', 'Mitotic cells (Spleen)': '0.957', 'Platelets': '0.186', 'Erythrocytes': '0.337', 'Hematopoietic stem cells': '0.420', 'B-cells (Spleen)': '-0.127', 'NK-cells (Spleen)': '-0.220', 'Amygdala excitatory': '3.2', 'Cerebellar inhibitory': '0.9', 'Cge interneuron': '1.5', 'Deep-layer corticothalamic and 6b': '5.1', 'Deep-layer intratelencephalic': '5.2', 'Deep-layer near-projecting': '3.3', 'Eccentric medium spiny neuron': '2.8', 'Hippocampal ca1-3': '2.7', 'Hippocampal ca4': '3.3', 'Hippocampal dentate gyrus': '1.8', 'Lamp5-lhx6 and chandelier': '0.6', 'Lower rhombic lip': '4.5', 'Mammillary body': '0.7', 'Medium spiny neuron': '3.6', 'Mge interneuron': '1.2', 'Midbrain-derived inhibitory': '0.7', 'Miscellaneous': '3.3', 'Splatter': '2.1', 'Thalamic excitatory': '2.7', 'Upper rhombic lip': '2.4', 'Upper-layer intratelencephalic': '3.8', 'Astrocyte': '0.8', 'Bergmann glia': '3.1', 'Central nervous system macrophage': '0.9', 'Choroid plexus epithelial cell': '0.3', 'Committed oligodendrocyte precursor': '1.1', 'Ependymal cell': '1.4', 'Oligodendrocyte': '0.6', 'Oligodendrocyte precursor cell': '0.8', 'Endothelial cell': '0.3', 'Pericyte': '1.2', 'Vascular associated smooth muscle cell': '0.9', 'Fibroblast': '0.8', 'Leukocyte': '1.3', 'Basophil': '2.1', 'Eosinophil': '0.4', 'Neutrophil': '1.0', 'Classical monocyte': '0.1', 'Non-classical monocyte': '0.5', 'Intermediate monocyte': '1.3', 'T-reg': '7.4', 'GdT-cell': '0.4', 'MAIT T-cell': '0.2', 'Memory CD4 T-cell': '1.4', 'Naive CD4 T-cell': '0.4', 'Memory CD8 T-cell': '1.7', 'Naive CD8 T-cell': '0.4', 'Memory B-cell': '0.6', 'Naive B-cell': '0.3', 'Plasmacytoid DC': '6.4', 'Myeloid DC': '1.2', 'NK-cell': '4.4', 'Total PBMC': '3.9', 'Vd2 gdTCR': '1.9', 'Memory CD4 T-cell Th1\\/Th17': '0.6', 'Memory CD4 T-cell Th17': '2.5', 'Memory CD4 T-cell Th2': '3.4', 'Non-Vd2 gdTCR': '1.6', 'Memory CD4 T-cell Th1': '2.8', 'Memory CD4 T-cell TFH': '1.9', 'Terminal effector memory CD4 T-cell': '1.3', 'Central memory CD8 T-cell': '2.9', 'Effector memory CD8 T-cell': '13.0', 'Terminal effector memory CD8 T-cell': '2.9', 'Non-switched memory B-cell': '1.3', 'Plasmablast': '35.5', 'Switched memory B-cell': '4.1', 'Exhausted memory B-cell': '2.8', 'Progenitor cell': '9.9', 'Memory T-reg': '13.8', 'Naive CD4 T-cell activated': '1.1', 'Naive CD8 T-cell activated': '2.6', 'Naive T-reg': '1.4'}
1OL5, 3E5A, 3HA6, 4C3P, 5LXM, 6BJC, 6VPG, 6VPH, 6VPI, 6VPJ, 6VPL, 6VPM, 6XKA
{'Adipose Tissue': 2.236638122923588, 'Adrenal Gland': 2.2545848062015503, 'Bladder': 1.6066238095238097, 'Blood': 25.90851313240043, 'Blood Vessel': 2.2428859925093634, 'Brain': 1.2397524337623012, 'Breast': 2.052158605664488, 'Cervix Uteri': 2.440394736842105, 'Colon': 4.887475160462131, 'Esophagus': 8.511514221453288, 'Fallopian Tube': 0.9627444444444444, 'Heart': 0.7330831823461091, 'Kidney': 1.047495393258427, 'Liver': 2.2983693805309735, 'Lung': 4.524037197231834, 'Muscle': 1.176385491905355, 'Nerve': 1.7138770597738286, 'Ovary': 1.297706388888889, 'Pancreas': 0.329782625, 'Pituitary': 0.5404050530035336, 'Prostate': 1.3003798367346937, 'Salivary Gland': 3.5522203703703705, 'Skin': 35.6846815920398, 'Small Intestine': 8.584858770053476, 'Spleen': 9.184461410788382, 'Stomach': 4.413848467966574, 'Testis': 53.94578947368421, 'Thyroid': 1.4700697856049003, 'Uterus': 1.1008838028169017, 'Vagina': 8.243314743589744}
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36.69, 42.2, 45.93, 55.09, 43.84, 44.44, 47.95, 42.63, 44.86, 41.83, 36.27, 47.55, 42.64, 40.97, 44.93, 45.45, 37.9, 39.12, 43.57, 40.32, 45.09, 40.8, 42.71, 41.41, 47.42, 40.75, 39.7, 42.77, 39.7, 39.3, 38.19, 44.4, 43.1, 40.21, 39.75, 40.47, 43.35, 44.49, 44.13, 42.0, 42.37, 37.51, 50.11, 42.42, 43.11, 43.0, 45.0, 38.12, 40.69, 39.81, 36.77, 46.88, 45.65, 41.16, 42.96, 57.73, 52.05, 40.99, 47.81, 44.72, 51.11, 50.03, 55.18, 64.34, 66.59, 77.23, 79.56, 79.71, 80.0, 83.11, 82.19, 86.33, 89.23, 81.69, 88.66, 91.77, 90.05, 88.55, 92.19, 90.82, 91.91, 90.99, 92.01, 89.59, 86.42, 91.11, 90.23, 87.51, 88.95, 87.0, 80.01, 83.01, 84.06, 79.27, 74.02, 75.71, 71.0, 53.64, 48.2, 42.21, 52.74, 55.0, 48.03, 52.79, 45.19, 56.19, 52.4, 55.26, 61.01, 59.87, 61.21, 67.8, 71.7, 74.53, 78.06, 73.89, 77.78, 73.1, 66.54, 73.0, 74.32, 73.55, 73.35, 63.9, 60.73, 60.68, 55.88, 55.25, 48.03, 47.71, 46.56, 50.19, 50.91, 44.28, 62.26, 66.3, 70.25, 69.14, 65.11, 77.99, 72.5, 77.87, 72.05, 76.96, 76.69, 65.39, 66.78, 64.05, 50.02, 60.36, 46.84, 52.82, 50.77, 51.49, 49.97, 53.38, 44.56, 50.81, 52.51, 52.83, 61.53, 64.6, 49.41, 51.02, 48.85, 55.18, 49.76, 49.02, 48.36, 51.21, 50.36, 45.0, 46.56, 40.79, 48.66, 42.74, 46.07, 53.92, 67.98, 76.11, 79.69, 87.86, 84.89, 84.76, 87.86, 85.38, 87.23, 86.89, 85.24, 86.24, 84.75, 86.84, 84.25, 82.91, 81.32, 69.3, 80.05, 79.42, 74.59, 70.59, 61.74, 56.45, 56.77, 52.81, 53.77, 51.22, 46.3, 43.62, 45.21, 39.22, 46.92, 42.19, 45.3, 45.09, 44.44, 44.81, 48.42, 52.77, 49.26, 48.15, 62.96, 68.24, 66.92, 72.46, 68.92, 71.58, 71.03, 60.5, 67.98, 67.07, 64.0, 64.61, 60.74, 65.86, 63.76, 67.86, 66.58, 75.54, 74.67, 82.15, 78.02, 80.72, 85.04, 86.57, 83.46, 87.01, 87.38, 87.38, 86.07, 85.46, 87.22, 86.58, 79.62, 82.58, 84.4, 78.02, 74.5, 70.21, 75.6, 72.22, 78.74, 77.97, 73.85, 74.11, 76.14, 73.52, 65.18, 68.16, 66.0, 57.55, 63.23, 59.7, 57.41, 55.49, 59.33, 60.45, 58.04, 61.73, 75.02, 72.66, 76.78, 80.39, 79.8, 81.3, 81.93, 79.23, 79.64, 79.8, 77.37, 78.67, 81.21, 81.56, 80.79, 84.26, 83.56, 84.4, 84.61, 83.96, 82.38, 81.64, 81.7, 73.81, 66.15, 62.75, 60.4, 55.54, 55.14, 54.31, 65.69, 62.29, 59.3, 79.38, 70.5, 77.08, 77.16, 78.52, 82.82, 70.76, 77.67, 80.49, 75.0, 68.62, 70.95, 77.71, 70.13, 70.31, 70.59, 67.83, 66.88, 71.74, 74.28, 72.26, 73.86, 76.28, 62.78, 74.75, 71.94, 66.31, 72.27, 64.0, 69.27, 56.13, 69.86, 61.19, 56.14, 51.36, 57.02, 60.4, 55.35, 45.24, 53.37, 50.31, 53.35, 50.32, 45.59, 44.0, 47.71, 47.33, 39.69, 51.9, 42.46, 47.55, 58.51, 56.38, 50.11, 52.19, 50.94, 50.8, 53.68, 67.81, 63.35, 64.93, 63.89, 54.65, 54.59, 65.71, 59.89, 58.19, 58.91, 65.74, 64.08, 60.49, 58.56, 59.46, 53.71, 52.7, 50.46, 51.7, 49.24, 55.92, 48.35, 54.39, 68.44, 60.18, 66.06, 75.56, 77.29, 77.2, 79.21, 82.53, 87.76, 87.81, 90.19, 86.13, 89.63, 87.76, 91.56, 88.53, 90.44, 86.83, 82.01, 84.06, 81.61, 76.27, 74.82, 70.45, 56.81, 55.93, 55.6, 58.83, 59.06, 54.41, 63.19, 65.84, 70.14, 74.08, 68.98, 70.28, 67.58, 69.8, 74.51, 61.99, 62.48, 64.68, 69.05, 70.68, 72.8, 78.59, 75.82, 79.84, 76.85, 74.77, 77.53, 79.34, 75.49, 71.03, 75.5, 76.6, 74.14, 73.98, 78.63, 80.59, 77.52, 83.08, 83.61, 83.2, 85.42, 88.21, 85.58, 86.0, 89.9, 90.59, 85.89, 86.03, 91.71, 90.29, 84.96, 89.01, 92.02, 90.15, 88.82, 90.0, 90.0, 83.77, 85.42, 87.42, 83.96, 82.14, 81.29, 77.77, 73.68, 73.67, 75.55, 78.85, 79.61, 77.83, 75.72, 75.18, 76.91, 77.95, 78.58, 80.12, 79.05, 81.89, 79.24, 76.07, 70.85, 68.97, 66.31, 59.3, 56.74, 50.95, 51.43, 48.07, 54.08, 50.5, 53.77, 49.33, 48.91, 44.86, 46.97, 46.2, 53.03, 56.85, 62.15, 71.42, 77.04, 84.71, 85.24, 84.86, 87.19, 87.88, 89.57, 89.61, 92.7, 91.87, 90.77, 91.88, 94.2, 88.98, 86.78, 92.13, 92.56, 78.17, 89.83, 90.87, 87.04, 80.72, 88.6, 82.98, 75.46, 82.09, 82.4, 77.25, 77.49, 78.35, 80.29, 80.77, 79.64, 80.83, 79.36, 76.18, 76.31, 80.52, 80.16, 77.63, 82.03, 84.49, 81.53, 75.37, 88.35, 90.45, 84.06, 80.56, 84.61, 86.48, 85.03, 84.88, 75.53, 83.12, 83.15, 84.0, 85.11, 82.63, 85.1, 83.56, 84.36, 85.66, 84.12, 81.73, 81.15, 78.94, 81.2, 81.85, 79.93, 79.52, 82.07, 81.85, 81.82, 83.64, 82.53, 83.48, 81.74, 81.35, 82.5, 78.58, 68.94, 74.17, 73.25, 70.96, 68.23, 61.41, 45.92]
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null
Component of an E-cadherin/ catenin adhesion complex composed of at least E-cadherin/CDH1, beta-catenin/CTNNB1 or gamma-catenin/JUP, and potentially alpha-catenin/CTNNA1. Forms a ternary complex composed of ADAM10, CADH1 and EPHA4,
null
null
KLRG1, SPEF1, DLGAP5, AJAP1, RAPGEF2, RAB8B, PIP5K1C, PKP2, TRPV4, CTNNB1, CAV1, DDR1, TBC1D2, CTNNA1, JUP, CTNND1, PSEN1, LIMA1, CDH1, JUP, ADAM10, CADH1 , EPHA4,
null
null
null
null
Homodimer
null
79.91949
0.474025
63.652329
0.787992
904
P12830
Q9UM11
null
degron_data
CDH1
MGPWSRSLSALLLLLQVSSWLCQEPEPCHPGFDAESYTFTVPRRHLERGRVLGRVNFEDCTGRQRTAYFSLDTRFKVGTDGVITVKRPLRFHNPQIHFLVYAWDSTYRKFSTKVTLNTVGHHHRPPPHQASVSGIQAELLTFPNSSPGLRRQKRDWVIPPISCPENEKGPFPKNLVQIKSNKDKEGKVFYSITGQGADTPPVGVFIIERETGWLKVTEPLDRERIATYTLFSHAVSSNGNAVEDPMEILITVTDQNDNKPEFTQEVFKGSVMEGALPGTSVMEVTATDADDDVNTYNAAIAYTILSQDPELPDKNMFTINRNTGVISVVTTGLDRESFPTYTLVVQAADLQGEGLSTTATAVITVTDTNDNPPIFNPTTYKGQVPENEANVVITTLKVTDADAPNTPAWEAVYTILNDDGGQFVVTTNPVNNDGILKTAKGLDFEAKQQYILHVAVTNVVPFEVSLTTSTATVTVDVLDVNEAPIFVPPEKRVEVSEDFGVGQEITSYTAQEPDTFMEQKITYRIWRDTANWLEINPDTGAISTRAELDREDFEHVKNSTYTALIIATDNGSPVATGTGTLLLILSDVNDNAPIPEPRTIFFCERNPKPQVINIIDADLPPNTSPFTAELTHGASANWTIQYNDPTQESIILKPKMALEVGDYKINLKLMDNQNKDQVTTLEVSVCDCEGAAGVCRKAQPVEAGLQIPAILGILGGILALLILILLLLLFLRRRAVVKEPLLPPEDDTRDNVYYYDEEGGGEEDQDFDLSQLHRGLDARPEVTRNDVAPTLMSVPRYLPRPANPDEIGNFIDENLKAADTDPTAPPYDSLLVFDYEGSGSEAASLSSLNSSESDKDQDYDYLNEWGNRFKKLADMYGGGEDD
Homo sapiens
Cell junction, adherens junction, Cell membrane, Endosome, Golgi apparatus, trans-Golgi network, Cytoplasm, Cell junction, desmosome
Tissue enhanced (parathyroid)
{'Ciliated cells': '119.1', 'Basal respiratory cells': '71.1', 'Club cells': '97.3', 'Ionocytes': '81.0', 'Mucus glandular cells': '155.0', 'Serous glandular cells': '67.8', 'Gastric mucus-secreting cells': '133.2', 'Proximal enterocytes': '140.9', 'Paneth cells': '125.1', 'Distal enterocytes': '307.5', 'Intestinal goblet cells': '173.5', 'Exocrine glandular cells': '-0.605', 'Basal prostatic cells': '68.3', 'Prostatic glandular cells': '186.7', 'Breast glandular cells': '0.773', 'Breast myoepithelial cells': '0.700', 'Glandular and luminal cells': '313.0', 'Secretory cells': '82.3', 'Basal keratinocytes': '102.5', 'Suprabasal keratinocytes': '162.6', 'Basal squamous epithelial cells': '51.0', 'Squamous epithelial cells': '106.9', 'Alveolar cells type 1': '0.437', 'Alveolar cells type 2': '0.706', 'Salivary duct cells': '95.9', 'Ductal cells': '0.541', 'Hepatocytes': '0.600', 'Cholangiocytes': '129.7', 'Proximal tubular cells': '0.042', 'Distal tubular cells': '0.0', 'Collecting duct cells': '143.9', 'Mesothelial cells': '0.799', 'Sertoli cells': '0.252', 'Granulosa cells': '12.9', 'Enteroendocrine cells': '92.4', 'Pancreatic endocrine cells': '78.1', 'Leydig cells': '0.264', 'Excitatory neurons': '0.7', 'Inhibitory neurons': '1.3', 'Cone photoreceptor cells': '0.0', 'Rod photoreceptor cells': '0.0', 'Bipolar cells': '0.2', 'Horizontal cells': '0.6', 'Astrocytes': '0.6', 'Oligodendrocyte precursor cells': '0.5', 'Oligodendrocytes': '29.9', 'Microglial cells': '0.9', 'Muller glia cells': '0.1', 'Schwann cells': '0.131', 'Spermatogonia': '0.392', 'Spermatocytes': '0.193', 'Early spermatids': '-0.217', 'Late spermatids': '-0.290', 'Oocytes': '16.9', 'Cytotrophoblasts': '119.2', 'Syncytiotrophoblasts': '45.0', 'Extravillous trophoblasts': '24.9', 'Endothelial cells': '6.1', 'Lymphatic endothelial cells': '0.4', 'Cardiomyocytes': '0.135', 'Skeletal myocytes': '0.107', 'Smooth muscle cells': '5.8', 'Adipocytes': '2.1', 'Melanocytes': '0.335', 'Fibroblasts': '6.5', 'Peritubular cells': '0.210', 'Endometrial stromal cells': '27.7', 'Ovarian stromal cells': '0.7', 'Undifferentiated cells': '101.6', 'T-cells': '2.9', 'B-cells': '4.4', 'Plasma cells': '6.1', 'Nk-cells': '0.0', 'Granulocytes': '8.4', 'Monocytes': '0.0', 'Macrophages': '6.0', 'Hofbauer cells': '4.3', 'Kupffer cells': '1.0', 'Dendritic cells': '5.9', 'Langerhans cells': '0.304', 'Erythroid cells': '0.036', 'Adipocytes (Subcutaneous)': '-0.081', 'Adipocytes (Visceral)': '-0.209', 'Breast glandular cells (progenitors)': '0.538', 'Adipocytes (Breast)': '-0.689', 'Colon enterocytes': '0.790', 'Colon enteroendocrine cells': '0.112', 'Enteric glia cells': '-0.048', 'Mitotic cells (Colon)': '0.299', 'Mitotic cells (Heart)': '0.120', 'Podocytes': '-0.118', 'Ascending Loop of Henle cells': '0.475', 'Intercalated cells': '0.212', 'Cholangiocyte': '0.090', 'NK-cells (Liver)': '-0.005', 'Respiratory ciliated cells': '-0.012', 'Mitotic cells (Lung)': '0.071', 'NK-cells (Lung)': '-0.266', 'B-cells (Lung)': '-0.296', 'Alpha cells': '0.270', 'Beta cells': '0.152', 'Prostate glandular cells': '0.764', 'Prostate basal glandular cells': '0.540', 'Urothelial cells': '0.205', 'Keratinocyte (other)': '0.510', 'Keratinocyte (granular)': '0.055', 'Hair cortex cells': '0.080', 'Inner root sheath cells': '0.131', 'Outer root sheath cells': '0.175', 'Sebaceous gland cells': '0.156', 'Eccrine sweat gland cells': '-0.207', 'Adipocytes (Skin)': '-0.244', 'Mitotic cells (Skin)': '0.442', 'Parietal cells': '0.654', 'Chief cells': '0.649', 'Gastric mucous cells': '0.781', 'Gastric enteroendocrine cells': '0.590', 'Mitotic cells (Stomach)': '0.445', 'Parafollicular cells': '0.173', 'Thyroid glandular cells': '0.865', 'Mitotic cells (Thyroid)': '-0.081', 'Adrenal cortex cells': '0.051', 'Adrenal medulla cells': '0.087', 'Mitotic cells (Adrenal gland)': '0.072', 'Minor salivary glandular cells': '0.371', 'Minor salivary gland ductal cells': '-0.142', 'Minor salivary gland basal cells': '0.582', 'Mitotic cells (Minor salivary gland)': '0.567', 'Adipocytes (Minor salivary gland)': '0.050', 'Somatotropes': '0.121', 'Lactotropes': '0.322', 'Gonadotropes': '0.330', 'Corticotropes': '0.180', 'Thyrotropes': '0.496', 'Undifferentiated cells (Pituitary gland)': '-0.108', 'Mitotic cells (Spleen)': '-0.228', 'Platelets': '-0.050', 'Erythrocytes': '-0.158', 'Hematopoietic stem cells': '-0.211', 'B-cells (Spleen)': '0.266', 'NK-cells (Spleen)': '0.309', 'Amygdala excitatory': '1.0', 'Cerebellar inhibitory': '0.9', 'Cge interneuron': '0.7', 'Deep-layer corticothalamic and 6b': '1.5', 'Deep-layer intratelencephalic': '0.7', 'Deep-layer near-projecting': '0.7', 'Eccentric medium spiny neuron': '0.6', 'Hippocampal ca1-3': '1.9', 'Hippocampal ca4': '1.2', 'Hippocampal dentate gyrus': '1.1', 'Lamp5-lhx6 and chandelier': '0.5', 'Lower rhombic lip': '0.8', 'Mammillary body': '0.6', 'Medium spiny neuron': '0.7', 'Mge interneuron': '1.7', 'Midbrain-derived inhibitory': '0.7', 'Miscellaneous': '0.9', 'Splatter': '3.8', 'Thalamic excitatory': '0.5', 'Upper rhombic lip': '0.8', 'Upper-layer intratelencephalic': '0.6', 'Astrocyte': '4.4', 'Bergmann glia': '0.2', 'Central nervous system macrophage': '0.6', 'Choroid plexus epithelial cell': '52.1', 'Committed oligodendrocyte precursor': '41.5', 'Ependymal cell': '4.8', 'Oligodendrocyte': '53.1', 'Oligodendrocyte precursor cell': '2.4', 'Endothelial cell': '0.7', 'Pericyte': '0.3', 'Vascular associated smooth muscle cell': '0.0', 'Fibroblast': '17.4', 'Leukocyte': '1.1', 'Basophil': '0.0', 'Eosinophil': '0.0', 'Neutrophil': '0.0', 'Classical monocyte': '0.0', 'Non-classical monocyte': '0.0', 'Intermediate monocyte': '0.0', 'T-reg': '2.3', 'GdT-cell': '0.0', 'MAIT T-cell': '0.0', 'Memory CD4 T-cell': '0.0', 'Naive CD4 T-cell': '0.1', 'Memory CD8 T-cell': '0.2', 'Naive CD8 T-cell': '0.3', 'Memory B-cell': '0.0', 'Naive B-cell': '0.1', 'Plasmacytoid DC': '46.6', 'Myeloid DC': '8.5', 'NK-cell': '0.1', 'Total PBMC': '0.7', 'Vd2 gdTCR': '0.0', 'Memory CD4 T-cell Th1\\/Th17': '0.1', 'Memory CD4 T-cell Th17': '0.2', 'Memory CD4 T-cell Th2': '2.9', 'Non-Vd2 gdTCR': '0.1', 'Memory CD4 T-cell Th1': '0.3', 'Memory CD4 T-cell TFH': '0.5', 'Terminal effector memory CD4 T-cell': '0.0', 'Central memory CD8 T-cell': '4.8', 'Effector memory CD8 T-cell': '0.0', 'Terminal effector memory CD8 T-cell': '0.6', 'Non-switched memory B-cell': '0.0', 'Plasmablast': '3.3', 'Switched memory B-cell': '0.0', 'Exhausted memory B-cell': '0.7', 'Progenitor cell': '2.3', 'Memory T-reg': '1.3', 'Naive CD4 T-cell activated': '0.3', 'Naive CD8 T-cell activated': '0.6', 'Naive T-reg': '0.1'}
1O6S, 2O72, 2OMT, 2OMU, 2OMV, 2OMX, 2OMY, 2OMZ, 3FF7, 3FF8, 3L6X, 3L6Y, 4ZT1, 4ZTE, 6CXY, 6OLE, 6OLF, 6OLG, 6VEL, 7STZ, 8H62
{'Adipose Tissue': 1.2125261088039867, 'Adrenal Gland': 0.1914223992248062, 'Bladder': 39.2033519047619, 'Blood': 1.340954264800861, 'Blood Vessel': 0.3121561692883895, 'Brain': 0.8550442199091597, 'Breast': 38.54918344226579, 'Cervix Uteri': 23.539115789473684, 'Colon': 43.41292142490372, 'Esophagus': 53.97513367404844, 'Fallopian Tube': 14.900277777777776, 'Heart': 0.119140469221835, 'Kidney': 25.040449438202245, 'Liver': 26.60802654867257, 'Lung': 35.447986366782004, 'Muscle': 0.1378936151930261, 'Nerve': 17.518468982229404, 'Ovary': 3.6515122222222223, 'Pancreas': 56.89676829268293, 'Pituitary': 24.68741660777385, 'Prostate': 61.279967346938776, 'Salivary Gland': 92.01685185185184, 'Skin': 79.77571720232172, 'Small Intestine': 71.7519320855615, 'Spleen': 10.061029045643156, 'Stomach': 58.07813805013927, 'Testis': 0.8144204986149585, 'Thyroid': 135.176797856049, 'Uterus': 1.442593943661972, 'Vagina': 86.52345512820513}
FZR1
MDQDYERRLLRQIVIQNENTMPRVTEMRRTLTPASSPVSSPSKHGDRFIPSRAGANWSVNFHRINENEKSPSQNRKAKDATSDNGKDGLAYSALLKNELLGAGIEKVQDPQTEDRRLQPSTPEKKGLFTYSLSTKRSSPDDGNDVSPYSLSPVSNKSQKLLRSPRKPTRKISKIPFKVLDAPELQDDFYLNLVDWSSLNVLSVGLGTCVYLWSACTSQVTRLCDLSVEGDSVTSVGWSERGNLVAVGTHKGFVQIWDAAAGKKLSMLEGHTARVGALAWNAEQLSSGSRDRMILQRDIRTPPLQSERRLQGHRQEVCGLKWSTDHQLLASGGNDNKLLVWNHSSLSPVQQYTEHLAAVKAIAWSPHQHGLLASGGGTADRCIRFWNTLTGQPLQCIDTGSQVCNLAWSKHANELVSTHGYSQNQILVWKYPSLTQVAKLTGHSYRVLYLAMSPDGEAIVTGAGDETLRFWNVFSKTRSTKVKWESVSVLNLFTRIR
Homo sapiens
Nucleus, Cytoplasm
Low tissue specificity
{'Ciliated cells': '15.1', 'Basal respiratory cells': '10.3', 'Club cells': '12.4', 'Ionocytes': '13.6', 'Mucus glandular cells': '10.5', 'Serous glandular cells': '6.5', 'Gastric mucus-secreting cells': '25.4', 'Proximal enterocytes': '13.9', 'Paneth cells': '12.7', 'Distal enterocytes': '20.8', 'Intestinal goblet cells': '19.0', 'Exocrine glandular cells': '-0.645', 'Basal prostatic cells': '13.1', 'Prostatic glandular cells': '9.1', 'Breast glandular cells': '0.694', 'Breast myoepithelial cells': '0.693', 'Glandular and luminal cells': '12.1', 'Secretory cells': '10.2', 'Basal keratinocytes': '17.9', 'Suprabasal keratinocytes': '21.7', 'Basal squamous epithelial cells': '6.2', 'Squamous epithelial cells': '12.1', 'Alveolar cells type 1': '0.205', 'Alveolar cells type 2': '-0.334', 'Salivary duct cells': '14.5', 'Ductal cells': '0.539', 'Hepatocytes': '0.294', 'Cholangiocytes': '21.0', 'Proximal tubular cells': '0.143', 'Distal tubular cells': '0.0', 'Collecting duct cells': '5.8', 'Mesothelial cells': '0.468', 'Sertoli cells': '-0.373', 'Granulosa cells': '12.6', 'Enteroendocrine cells': '17.1', 'Pancreatic endocrine cells': '10.2', 'Leydig cells': '-0.471', 'Excitatory neurons': '6.1', 'Inhibitory neurons': '8.7', 'Cone photoreceptor cells': '17.0', 'Rod photoreceptor cells': '16.3', 'Bipolar cells': '20.5', 'Horizontal cells': '24.5', 'Astrocytes': '6.2', 'Oligodendrocyte precursor cells': '6.1', 'Oligodendrocytes': '9.6', 'Microglial cells': '3.6', 'Muller glia cells': '8.2', 'Schwann cells': '0.004', 'Spermatogonia': '-0.192', 'Spermatocytes': '0.127', 'Early spermatids': '0.572', 'Late spermatids': '0.513', 'Oocytes': '22.1', 'Cytotrophoblasts': '21.6', 'Syncytiotrophoblasts': '43.6', 'Extravillous trophoblasts': '13.0', 'Endothelial cells': '9.4', 'Lymphatic endothelial cells': '5.6', 'Cardiomyocytes': '0.536', 'Skeletal myocytes': '-0.121', 'Smooth muscle cells': '9.6', 'Adipocytes': '7.6', 'Melanocytes': '0.162', 'Fibroblasts': '8.9', 'Peritubular cells': '-0.334', 'Endometrial stromal cells': '7.5', 'Ovarian stromal cells': '13.2', 'Undifferentiated cells': '12.9', 'T-cells': '13.0', 'B-cells': '15.2', 'Plasma cells': '11.5', 'Nk-cells': '12.4', 'Granulocytes': '9.5', 'Monocytes': '17.3', 'Macrophages': '11.1', 'Hofbauer cells': '14.8', 'Kupffer cells': '8.7', 'Dendritic cells': '13.6', 'Langerhans cells': '0.203', 'Erythroid cells': '0.118', 'Adipocytes (Subcutaneous)': '-0.390', 'Adipocytes (Visceral)': '-0.336', 'Breast glandular cells (progenitors)': '0.528', 'Adipocytes (Breast)': '-0.646', 'Colon enterocytes': '-0.217', 'Colon enteroendocrine cells': '0.206', 'Enteric glia cells': '0.408', 'Mitotic cells (Colon)': '-0.207', 'Mitotic cells (Heart)': '0.501', 'Podocytes': '-0.122', 'Ascending Loop of Henle cells': '0.491', 'Intercalated cells': '0.031', 'Cholangiocyte': '0.130', 'NK-cells (Liver)': '0.008', 'Respiratory ciliated cells': '0.191', 'Mitotic cells (Lung)': '-0.038', 'NK-cells (Lung)': '0.396', 'B-cells (Lung)': '0.213', 'Alpha cells': '0.448', 'Beta cells': '0.319', 'Prostate glandular cells': '0.155', 'Prostate basal glandular cells': '0.353', 'Urothelial cells': '0.294', 'Keratinocyte (other)': '0.428', 'Keratinocyte (granular)': '0.003', 'Hair cortex cells': '-0.107', 'Inner root sheath cells': '-0.111', 'Outer root sheath cells': '0.062', 'Sebaceous gland cells': '-0.201', 'Eccrine sweat gland cells': '-0.099', 'Adipocytes (Skin)': '-0.310', 'Mitotic cells (Skin)': '0.182', 'Parietal cells': '-0.532', 'Chief cells': '-0.489', 'Gastric mucous cells': '-0.101', 'Gastric enteroendocrine cells': '-0.281', 'Mitotic cells (Stomach)': '0.194', 'Parafollicular cells': '0.113', 'Thyroid glandular cells': '0.314', 'Mitotic cells (Thyroid)': '-0.021', 'Adrenal cortex cells': '0.631', 'Adrenal medulla cells': '0.075', 'Mitotic cells (Adrenal gland)': '-0.154', 'Minor salivary glandular cells': '0.476', 'Minor salivary gland ductal cells': '0.183', 'Minor salivary gland basal cells': '0.387', 'Mitotic cells (Minor salivary gland)': '0.308', 'Adipocytes (Minor salivary gland)': '0.194', 'Somatotropes': '0.248', 'Lactotropes': '0.442', 'Gonadotropes': '0.317', 'Corticotropes': '0.170', 'Thyrotropes': '0.184', 'Undifferentiated cells (Pituitary gland)': '-0.208', 'Mitotic cells (Spleen)': '-0.169', 'Platelets': '-0.178', 'Erythrocytes': '0.007', 'Hematopoietic stem cells': '-0.255', 'B-cells (Spleen)': '0.394', 'NK-cells (Spleen)': '0.306', 'Amygdala excitatory': '16.2', 'Cerebellar inhibitory': '15.5', 'Cge interneuron': '20.7', 'Deep-layer corticothalamic and 6b': '17.2', 'Deep-layer intratelencephalic': '13.9', 'Deep-layer near-projecting': '17.9', 'Eccentric medium spiny neuron': '17.0', 'Hippocampal ca1-3': '11.9', 'Hippocampal ca4': '9.6', 'Hippocampal dentate gyrus': '10.4', 'Lamp5-lhx6 and chandelier': '19.9', 'Lower rhombic lip': '14.6', 'Mammillary body': '16.1', 'Medium spiny neuron': '12.2', 'Mge interneuron': '19.8', 'Midbrain-derived inhibitory': '17.7', 'Miscellaneous': '12.3', 'Splatter': '17.9', 'Thalamic excitatory': '20.4', 'Upper rhombic lip': '12.0', 'Upper-layer intratelencephalic': '10.3', 'Astrocyte': '12.8', 'Bergmann glia': '11.5', 'Central nervous system macrophage': '12.6', 'Choroid plexus epithelial cell': '9.8', 'Committed oligodendrocyte precursor': '18.7', 'Ependymal cell': '17.5', 'Oligodendrocyte': '18.6', 'Oligodendrocyte precursor cell': '13.5', 'Endothelial cell': '14.0', 'Pericyte': '14.0', 'Vascular associated smooth muscle cell': '16.8', 'Fibroblast': '12.0', 'Leukocyte': '18.7', 'Basophil': '15.8', 'Eosinophil': '2.0', 'Neutrophil': '19.6', 'Classical monocyte': '15.0', 'Non-classical monocyte': '11.7', 'Intermediate monocyte': '9.6', 'T-reg': '11.2', 'GdT-cell': '1.1', 'MAIT T-cell': '13.4', 'Memory CD4 T-cell': '1.0', 'Naive CD4 T-cell': '16.7', 'Memory CD8 T-cell': '0.7', 'Naive CD8 T-cell': '24.1', 'Memory B-cell': '1.0', 'Naive B-cell': '19.2', 'Plasmacytoid DC': '10.4', 'Myeloid DC': '9.7', 'NK-cell': '24.3', 'Total PBMC': '8.2', 'Vd2 gdTCR': '13.3', 'Memory CD4 T-cell Th1\\/Th17': '18.0', 'Memory CD4 T-cell Th17': '27.0', 'Memory CD4 T-cell Th2': '29.5', 'Non-Vd2 gdTCR': '14.2', 'Memory CD4 T-cell Th1': '33.9', 'Memory CD4 T-cell TFH': '48.9', 'Terminal effector memory CD4 T-cell': '14.6', 'Central memory CD8 T-cell': '15.4', 'Effector memory CD8 T-cell': '13.7', 'Terminal effector memory CD8 T-cell': '14.5', 'Non-switched memory B-cell': '13.2', 'Plasmablast': '9.1', 'Switched memory B-cell': '11.3', 'Exhausted memory B-cell': '14.1', 'Progenitor cell': '6.1', 'Memory T-reg': '47.3', 'Naive CD4 T-cell activated': '13.8', 'Naive CD8 T-cell activated': '18.5', 'Naive T-reg': '31.5'}
4UI9, 5L9T, 5L9U, 7QE7, 8S4G, 8TAR, 8TAU
{'Adipose Tissue': 19.46810880398671, 'Adrenal Gland': 29.2876007751938, 'Bladder': 27.38285714285714, 'Blood': 19.547019375672768, 'Blood Vessel': 27.599573033707863, 'Brain': 26.95018433005299, 'Breast': 26.63632897603486, 'Cervix Uteri': 40.770526315789475, 'Colon': 23.282314505776636, 'Esophagus': 23.994503806228373, 'Fallopian Tube': 34.57222222222222, 'Heart': 8.733104529616725, 'Kidney': 17.97647191011236, 'Liver': 14.69487168141593, 'Lung': 26.58581314878893, 'Muscle': 11.545407222914072, 'Nerve': 34.77274636510501, 'Ovary': 42.36077777777778, 'Pancreas': 10.27298475609756, 'Pituitary': 58.10975265017668, 'Prostate': 34.24644897959183, 'Salivary Gland': 25.609259259259257, 'Skin': 32.51415257048093, 'Small Intestine': 25.308288770053473, 'Spleen': 28.76311203319502, 'Stomach': 17.90639554317549, 'Testis': 69.12493074792243, 'Thyroid': 48.03656814701378, 'Uterus': 41.83204225352112, 'Vagina': 35.41961538461538}
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[48.74, 65.79, 66.88, 68.11, 73.58, 64.35, 67.2, 68.08, 57.4, 57.33, 55.9, 50.11, 53.76, 50.32, 48.08, 44.3, 44.63, 37.47, 38.33, 37.51, 42.12, 39.89, 35.09, 39.76, 36.81, 40.28, 36.53, 41.49, 37.46, 46.73, 47.41, 44.38, 46.84, 37.55, 47.39, 43.72, 52.32, 48.9, 44.92, 48.06, 49.76, 58.26, 59.21, 69.81, 74.42, 80.03, 81.9, 82.76, 83.32, 83.4, 81.06, 81.36, 76.28, 72.48, 76.96, 80.32, 84.35, 84.86, 83.55, 82.62, 85.04, 83.12, 78.93, 78.19, 72.97, 68.26, 57.09, 43.06, 39.48, 33.14, 38.61, 35.7, 40.7, 40.35, 37.26, 33.05, 35.37, 40.71, 36.88, 37.81, 39.81, 51.59, 50.27, 46.65, 55.15, 58.59, 62.37, 75.81, 82.37, 83.93, 87.34, 87.04, 87.51, 89.73, 89.37, 87.12, 87.93, 87.74, 86.49, 85.3, 81.44, 82.03, 82.9, 83.55, 84.21, 81.07, 75.77, 67.77, 57.91, 51.06, 48.54, 43.66, 36.63, 34.24, 36.3, 31.12, 31.05, 25.71, 30.15, 30.93, 33.85, 42.63, 47.11, 52.26, 60.84, 68.42, 80.37, 82.76, 81.25, 80.77, 73.85, 64.61, 54.55, 45.85, 39.83, 31.34, 35.56, 33.46, 39.52, 47.08, 42.77, 44.79, 53.14, 55.06, 56.9, 56.42, 64.13, 67.78, 67.09, 75.61, 77.03, 81.96, 83.64, 83.97, 84.11, 84.17, 87.04, 85.99, 86.27, 87.46, 85.65, 84.35, 78.8, 68.46, 65.61, 62.2, 63.02, 64.15, 76.27, 80.67, 88.97, 91.52, 93.69, 94.7, 96.69, 95.93, 97.28, 97.97, 98.29, 97.96, 97.89, 97.36, 95.22, 97.86, 97.54, 97.04, 97.82, 97.89, 98.38, 98.56, 98.6, 98.6, 98.65, 98.67, 98.59, 98.32, 97.59, 98.17, 97.92, 98.46, 98.56, 98.58, 98.58, 98.29, 97.9, 95.74, 97.17, 97.85, 98.19, 98.37, 98.34, 98.35, 97.57, 96.7, 96.37, 97.2, 96.59, 97.33, 97.4, 96.75, 96.81, 96.49, 95.76, 96.45, 94.59, 88.81, 80.43, 81.11, 90.55, 94.74, 96.79, 98.29, 98.51, 98.63, 98.63, 98.5, 98.58, 97.63, 95.66, 96.28, 96.61, 97.03, 98.03, 98.37, 98.5, 98.59, 98.38, 98.4, 97.72, 97.07, 96.28, 96.68, 97.36, 96.99, 97.61, 98.18, 97.31, 95.89, 93.49, 95.12, 94.3, 96.49, 96.08, 94.88, 93.79, 94.21, 94.19, 93.77, 92.36, 96.8, 96.97, 97.94, 98.08, 98.66, 98.4, 98.62, 98.65, 98.34, 97.64, 95.64, 93.66, 93.04, 94.15, 96.29, 97.35, 98.4, 98.51, 98.66, 98.58, 97.66, 98.16, 97.74, 98.11, 96.45, 95.38, 93.33, 93.42, 93.05, 92.13, 89.95, 84.05, 70.24, 64.42, 64.46, 65.05, 80.98, 91.34, 94.37, 96.38, 95.66, 95.4, 98.39, 98.03, 98.25, 98.48, 98.76, 98.36, 98.49, 98.62, 98.51, 97.6, 96.32, 89.55, 91.74, 92.13, 93.78, 96.47, 97.88, 98.53, 98.77, 98.81, 98.56, 98.63, 98.47, 98.53, 98.55, 98.71, 98.49, 98.23, 97.31, 92.94, 82.38, 82.13, 89.09, 92.36, 95.05, 96.36, 95.93, 96.75, 97.48, 98.03, 97.92, 97.77, 98.43, 98.29, 98.19, 98.38, 98.74, 98.75, 98.74, 98.71, 98.62, 98.27, 97.6, 96.18, 95.51, 95.32, 94.73, 94.89, 97.3, 98.28, 98.61, 98.81, 98.63, 98.26, 97.5, 96.35, 97.15, 97.49, 97.71, 97.88, 98.48, 98.56, 98.42, 98.15, 97.13, 96.09, 92.56, 95.23, 94.37, 95.34, 94.74, 94.86, 91.29, 94.41, 96.8, 96.45, 95.2, 94.85, 96.21, 97.9, 98.52, 98.44, 98.71, 98.67, 98.41, 98.06, 96.42, 94.54, 91.25, 91.68, 93.07, 95.94, 97.84, 98.32, 98.55, 98.64, 98.48, 95.8, 85.86, 89.33, 89.51, 95.54, 96.36, 98.11, 97.49, 96.94, 96.35, 94.09, 95.16, 94.29, 92.89, 92.35, 91.69, 92.43, 92.02, 92.96, 94.71, 95.85, 94.76, 90.94, 97.33, 96.23, 97.51, 97.91, 98.46, 98.45, 98.54, 98.51, 98.44, 98.08, 97.7, 96.94, 95.47, 95.66, 95.23, 96.44, 98.08, 98.51, 98.66, 98.43, 98.36, 96.5, 97.14, 98.09, 98.37, 98.5, 98.55, 98.18, 97.72, 94.67, 93.01, 90.99, 80.8, 67.85, 56.79, 45.71, 39.49, 36.36, 34.27, 37.39, 36.7, 42.14, 44.57, 51.42, 56.48, 63.39, 74.0, 83.31, 83.18, 83.65, 85.26, 80.64, 74.37, 77.86, 66.93]
[0.97, 0.7, 0.78, 0.56, 0.72, 0.7, 0.71, 0.76, 0.55, 0.64, 0.74, 0.74, 0.68, 0.74, 0.77, 0.88, 0.87, 0.91, 0.99, 1.0, 1.0, 1.0, 0.98, 1.0, 0.96, 1.0, 1.0, 0.99, 1.0, 0.99, 0.98, 0.99, 0.96, 0.97, 0.92, 0.9, 0.94, 0.92, 0.93, 0.79, 0.9, 0.48, 0.95, 0.75, 0.64, 0.44, 0.89, 0.91, 0.7, 0.28, 0.17, 0.82, 0.53, 0.84, 0.17, 0.52, 0.26, 0.76, 0.25, 0.21, 0.64, 0.76, 0.29, 0.46, 0.67, 0.51, 0.83, 0.83, 0.72, 0.54, 0.65, 0.66, 0.75, 0.72, 0.75, 0.93, 0.76, 0.76, 0.88, 0.92, 0.68, 0.57, 0.44, 0.71, 0.41, 0.27, 0.55, 0.37, 0.43, 0.16, 0.63, 0.39, 0.08, 0.23, 0.35, 0.26, 0.03, 0.42, 0.75, 0.38, 0.3, 0.15, 0.32, 0.19, 0.37, 0.8, 0.31, 0.62, 0.39, 0.55, 0.56, 0.55, 0.77, 0.63, 0.88, 0.97, 0.82, 0.96, 0.71, 0.72, 0.65, 0.77, 0.75, 0.81, 0.55, 0.57, 0.19, 0.55, 0.36, 0.35, 0.65, 0.41, 0.65, 0.66, 0.82, 0.94, 0.7, 0.62, 0.87, 0.7, 0.63, 0.67, 0.68, 0.68, 0.46, 0.23, 0.88, 0.93, 0.28, 0.93, 0.3, 0.75, 0.23, 0.13, 0.26, 0.34, 0.0, 0.22, 0.52, 0.04, 0.63, 0.77, 0.19, 0.9, 0.51, 0.84, 0.9, 0.45, 0.38, 0.74, 0.11, 0.45, 0.4, 0.81, 0.24, 0.59, 0.38, 0.56, 0.24, 0.77, 0.01, 0.52, 0.61, 0.05, 0.46, 0.38, 0.27, 0.06, 0.27, 0.06, 0.24, 0.01, 0.1, 0.26, 0.1, 0.01, 0.48, 0.59, 0.21, 0.21, 0.02, 0.0, 0.09, 0.01, 0.1, 0.12, 0.3, 0.12, 0.0, 0.32, 0.09, 0.1, 0.23, 0.29, 0.73, 0.71, 0.5, 0.6, 0.66, 0.45, 0.61, 0.11, 0.06, 0.4, 0.03, 0.54, 0.92, 0.45, 0.63, 0.05, 0.39, 0.01, 0.0, 0.01, 0.07, 0.07, 0.08, 0.1, 0.58, 0.7, 0.05, 0.5, 0.16, 0.0, 0.0, 0.0, 0.0, 0.01, 0.47, 0.46, 0.02, 0.29, 0.03, 0.01, 0.01, 0.13, 0.25, 0.29, 0.9, 0.54, 0.48, 0.66, 0.45, 0.57, 0.34, 0.31, 0.1, 0.63, 0.53, 0.09, 0.78, 0.27, 0.1, 0.0, 0.0, 0.03, 0.13, 0.08, 0.12, 0.1, 0.51, 0.31, 0.28, 0.02, 0.0, 0.04, 0.0, 0.0, 0.54, 0.21, 0.49, 0.21, 0.0, 0.02, 0.07, 0.08, 0.19, 0.23, 0.74, 0.41, 0.66, 0.55, 0.96, 0.81, 0.4, 0.35, 0.18, 0.58, 0.0, 0.55, 0.32, 0.03, 0.72, 0.46, 0.08, 0.0, 0.01, 0.01, 0.08, 0.53, 0.09, 0.07, 0.59, 0.38, 0.33, 0.57, 0.13, 0.0, 0.0, 0.0, 0.0, 0.0, 0.23, 0.18, 0.27, 0.21, 0.0, 0.0, 0.01, 0.01, 0.39, 0.45, 0.86, 0.32, 0.56, 0.66, 0.36, 0.56, 0.27, 0.54, 0.09, 0.58, 0.53, 0.04, 0.62, 0.11, 0.1, 0.0, 0.05, 0.01, 0.05, 0.07, 0.09, 0.04, 0.47, 0.52, 0.47, 0.5, 0.04, 0.01, 0.0, 0.0, 0.0, 0.0, 0.0, 0.03, 0.49, 0.64, 0.08, 0.39, 0.16, 0.0, 0.18, 0.01, 0.01, 0.23, 0.07, 0.65, 0.55, 0.23, 0.59, 0.69, 0.44, 0.32, 0.53, 0.14, 0.59, 0.06, 0.36, 0.0, 0.07, 0.0, 0.0, 0.13, 0.09, 0.14, 0.04, 0.0, 0.45, 0.43, 0.3, 0.41, 0.09, 0.01, 0.0, 0.0, 0.0, 0.0, 0.0, 0.52, 0.9, 0.38, 0.15, 0.04, 0.01, 0.0, 0.0, 0.05, 0.45, 0.14, 0.67, 0.62, 0.14, 0.4, 0.49, 0.28, 0.16, 0.48, 0.0, 0.56, 0.41, 0.07, 0.72, 0.51, 0.14, 0.0, 0.01, 0.02, 0.14, 0.06, 0.22, 0.04, 0.29, 0.43, 0.0, 0.26, 0.11, 0.0, 0.0, 0.0, 0.0, 0.0, 0.18, 0.19, 0.42, 0.18, 0.02, 0.16, 0.0, 0.01, 0.44, 0.0, 0.02, 0.5, 0.55, 0.84, 0.91, 0.81, 0.74, 0.92, 0.6, 0.89, 0.81, 0.78, 0.77, 0.64, 0.41, 0.64, 0.9, 0.39, 0.7, 0.76, 0.36, 0.69, 0.73, 0.92]
null
Component of an E-cadherin/ catenin adhesion complex composed of at least E-cadherin/CDH1, beta-catenin/CTNNB1 or gamma-catenin/JUP, and potentially alpha-catenin/CTNNA1. Forms a ternary complex composed of ADAM10, CADH1 and EPHA4,
null
null
KLRG1, SPEF1, DLGAP5, AJAP1, RAPGEF2, RAB8B, PIP5K1C, PKP2, TRPV4, CTNNB1, CAV1, DDR1, TBC1D2, CTNNA1, JUP, CTNND1, PSEN1, LIMA1, CDH1, JUP, ADAM10, CADH1 , EPHA4,
null
null
null
null
Homodimer
null
79.91949
0.474025
82.2
0.402923
1,605
P12830
Q9UM11-2
null
degron_data
CDH1
MGPWSRSLSALLLLLQVSSWLCQEPEPCHPGFDAESYTFTVPRRHLERGRVLGRVNFEDCTGRQRTAYFSLDTRFKVGTDGVITVKRPLRFHNPQIHFLVYAWDSTYRKFSTKVTLNTVGHHHRPPPHQASVSGIQAELLTFPNSSPGLRRQKRDWVIPPISCPENEKGPFPKNLVQIKSNKDKEGKVFYSITGQGADTPPVGVFIIERETGWLKVTEPLDRERIATYTLFSHAVSSNGNAVEDPMEILITVTDQNDNKPEFTQEVFKGSVMEGALPGTSVMEVTATDADDDVNTYNAAIAYTILSQDPELPDKNMFTINRNTGVISVVTTGLDRESFPTYTLVVQAADLQGEGLSTTATAVITVTDTNDNPPIFNPTTYKGQVPENEANVVITTLKVTDADAPNTPAWEAVYTILNDDGGQFVVTTNPVNNDGILKTAKGLDFEAKQQYILHVAVTNVVPFEVSLTTSTATVTVDVLDVNEAPIFVPPEKRVEVSEDFGVGQEITSYTAQEPDTFMEQKITYRIWRDTANWLEINPDTGAISTRAELDREDFEHVKNSTYTALIIATDNGSPVATGTGTLLLILSDVNDNAPIPEPRTIFFCERNPKPQVINIIDADLPPNTSPFTAELTHGASANWTIQYNDPTQESIILKPKMALEVGDYKINLKLMDNQNKDQVTTLEVSVCDCEGAAGVCRKAQPVEAGLQIPAILGILGGILALLILILLLLLFLRRRAVVKEPLLPPEDDTRDNVYYYDEEGGGEEDQDFDLSQLHRGLDARPEVTRNDVAPTLMSVPRYLPRPANPDEIGNFIDENLKAADTDPTAPPYDSLLVFDYEGSGSEAASLSSLNSSESDKDQDYDYLNEWGNRFKKLADMYGGGEDD
Homo sapiens
Cell junction, adherens junction, Cell membrane, Endosome, Golgi apparatus, trans-Golgi network, Cytoplasm, Cell junction, desmosome
Tissue enhanced (parathyroid)
{'Ciliated cells': '119.1', 'Basal respiratory cells': '71.1', 'Club cells': '97.3', 'Ionocytes': '81.0', 'Mucus glandular cells': '155.0', 'Serous glandular cells': '67.8', 'Gastric mucus-secreting cells': '133.2', 'Proximal enterocytes': '140.9', 'Paneth cells': '125.1', 'Distal enterocytes': '307.5', 'Intestinal goblet cells': '173.5', 'Exocrine glandular cells': '-0.605', 'Basal prostatic cells': '68.3', 'Prostatic glandular cells': '186.7', 'Breast glandular cells': '0.773', 'Breast myoepithelial cells': '0.700', 'Glandular and luminal cells': '313.0', 'Secretory cells': '82.3', 'Basal keratinocytes': '102.5', 'Suprabasal keratinocytes': '162.6', 'Basal squamous epithelial cells': '51.0', 'Squamous epithelial cells': '106.9', 'Alveolar cells type 1': '0.437', 'Alveolar cells type 2': '0.706', 'Salivary duct cells': '95.9', 'Ductal cells': '0.541', 'Hepatocytes': '0.600', 'Cholangiocytes': '129.7', 'Proximal tubular cells': '0.042', 'Distal tubular cells': '0.0', 'Collecting duct cells': '143.9', 'Mesothelial cells': '0.799', 'Sertoli cells': '0.252', 'Granulosa cells': '12.9', 'Enteroendocrine cells': '92.4', 'Pancreatic endocrine cells': '78.1', 'Leydig cells': '0.264', 'Excitatory neurons': '0.7', 'Inhibitory neurons': '1.3', 'Cone photoreceptor cells': '0.0', 'Rod photoreceptor cells': '0.0', 'Bipolar cells': '0.2', 'Horizontal cells': '0.6', 'Astrocytes': '0.6', 'Oligodendrocyte precursor cells': '0.5', 'Oligodendrocytes': '29.9', 'Microglial cells': '0.9', 'Muller glia cells': '0.1', 'Schwann cells': '0.131', 'Spermatogonia': '0.392', 'Spermatocytes': '0.193', 'Early spermatids': '-0.217', 'Late spermatids': '-0.290', 'Oocytes': '16.9', 'Cytotrophoblasts': '119.2', 'Syncytiotrophoblasts': '45.0', 'Extravillous trophoblasts': '24.9', 'Endothelial cells': '6.1', 'Lymphatic endothelial cells': '0.4', 'Cardiomyocytes': '0.135', 'Skeletal myocytes': '0.107', 'Smooth muscle cells': '5.8', 'Adipocytes': '2.1', 'Melanocytes': '0.335', 'Fibroblasts': '6.5', 'Peritubular cells': '0.210', 'Endometrial stromal cells': '27.7', 'Ovarian stromal cells': '0.7', 'Undifferentiated cells': '101.6', 'T-cells': '2.9', 'B-cells': '4.4', 'Plasma cells': '6.1', 'Nk-cells': '0.0', 'Granulocytes': '8.4', 'Monocytes': '0.0', 'Macrophages': '6.0', 'Hofbauer cells': '4.3', 'Kupffer cells': '1.0', 'Dendritic cells': '5.9', 'Langerhans cells': '0.304', 'Erythroid cells': '0.036', 'Adipocytes (Subcutaneous)': '-0.081', 'Adipocytes (Visceral)': '-0.209', 'Breast glandular cells (progenitors)': '0.538', 'Adipocytes (Breast)': '-0.689', 'Colon enterocytes': '0.790', 'Colon enteroendocrine cells': '0.112', 'Enteric glia cells': '-0.048', 'Mitotic cells (Colon)': '0.299', 'Mitotic cells (Heart)': '0.120', 'Podocytes': '-0.118', 'Ascending Loop of Henle cells': '0.475', 'Intercalated cells': '0.212', 'Cholangiocyte': '0.090', 'NK-cells (Liver)': '-0.005', 'Respiratory ciliated cells': '-0.012', 'Mitotic cells (Lung)': '0.071', 'NK-cells (Lung)': '-0.266', 'B-cells (Lung)': '-0.296', 'Alpha cells': '0.270', 'Beta cells': '0.152', 'Prostate glandular cells': '0.764', 'Prostate basal glandular cells': '0.540', 'Urothelial cells': '0.205', 'Keratinocyte (other)': '0.510', 'Keratinocyte (granular)': '0.055', 'Hair cortex cells': '0.080', 'Inner root sheath cells': '0.131', 'Outer root sheath cells': '0.175', 'Sebaceous gland cells': '0.156', 'Eccrine sweat gland cells': '-0.207', 'Adipocytes (Skin)': '-0.244', 'Mitotic cells (Skin)': '0.442', 'Parietal cells': '0.654', 'Chief cells': '0.649', 'Gastric mucous cells': '0.781', 'Gastric enteroendocrine cells': '0.590', 'Mitotic cells (Stomach)': '0.445', 'Parafollicular cells': '0.173', 'Thyroid glandular cells': '0.865', 'Mitotic cells (Thyroid)': '-0.081', 'Adrenal cortex cells': '0.051', 'Adrenal medulla cells': '0.087', 'Mitotic cells (Adrenal gland)': '0.072', 'Minor salivary glandular cells': '0.371', 'Minor salivary gland ductal cells': '-0.142', 'Minor salivary gland basal cells': '0.582', 'Mitotic cells (Minor salivary gland)': '0.567', 'Adipocytes (Minor salivary gland)': '0.050', 'Somatotropes': '0.121', 'Lactotropes': '0.322', 'Gonadotropes': '0.330', 'Corticotropes': '0.180', 'Thyrotropes': '0.496', 'Undifferentiated cells (Pituitary gland)': '-0.108', 'Mitotic cells (Spleen)': '-0.228', 'Platelets': '-0.050', 'Erythrocytes': '-0.158', 'Hematopoietic stem cells': '-0.211', 'B-cells (Spleen)': '0.266', 'NK-cells (Spleen)': '0.309', 'Amygdala excitatory': '1.0', 'Cerebellar inhibitory': '0.9', 'Cge interneuron': '0.7', 'Deep-layer corticothalamic and 6b': '1.5', 'Deep-layer intratelencephalic': '0.7', 'Deep-layer near-projecting': '0.7', 'Eccentric medium spiny neuron': '0.6', 'Hippocampal ca1-3': '1.9', 'Hippocampal ca4': '1.2', 'Hippocampal dentate gyrus': '1.1', 'Lamp5-lhx6 and chandelier': '0.5', 'Lower rhombic lip': '0.8', 'Mammillary body': '0.6', 'Medium spiny neuron': '0.7', 'Mge interneuron': '1.7', 'Midbrain-derived inhibitory': '0.7', 'Miscellaneous': '0.9', 'Splatter': '3.8', 'Thalamic excitatory': '0.5', 'Upper rhombic lip': '0.8', 'Upper-layer intratelencephalic': '0.6', 'Astrocyte': '4.4', 'Bergmann glia': '0.2', 'Central nervous system macrophage': '0.6', 'Choroid plexus epithelial cell': '52.1', 'Committed oligodendrocyte precursor': '41.5', 'Ependymal cell': '4.8', 'Oligodendrocyte': '53.1', 'Oligodendrocyte precursor cell': '2.4', 'Endothelial cell': '0.7', 'Pericyte': '0.3', 'Vascular associated smooth muscle cell': '0.0', 'Fibroblast': '17.4', 'Leukocyte': '1.1', 'Basophil': '0.0', 'Eosinophil': '0.0', 'Neutrophil': '0.0', 'Classical monocyte': '0.0', 'Non-classical monocyte': '0.0', 'Intermediate monocyte': '0.0', 'T-reg': '2.3', 'GdT-cell': '0.0', 'MAIT T-cell': '0.0', 'Memory CD4 T-cell': '0.0', 'Naive CD4 T-cell': '0.1', 'Memory CD8 T-cell': '0.2', 'Naive CD8 T-cell': '0.3', 'Memory B-cell': '0.0', 'Naive B-cell': '0.1', 'Plasmacytoid DC': '46.6', 'Myeloid DC': '8.5', 'NK-cell': '0.1', 'Total PBMC': '0.7', 'Vd2 gdTCR': '0.0', 'Memory CD4 T-cell Th1\\/Th17': '0.1', 'Memory CD4 T-cell Th17': '0.2', 'Memory CD4 T-cell Th2': '2.9', 'Non-Vd2 gdTCR': '0.1', 'Memory CD4 T-cell Th1': '0.3', 'Memory CD4 T-cell TFH': '0.5', 'Terminal effector memory CD4 T-cell': '0.0', 'Central memory CD8 T-cell': '4.8', 'Effector memory CD8 T-cell': '0.0', 'Terminal effector memory CD8 T-cell': '0.6', 'Non-switched memory B-cell': '0.0', 'Plasmablast': '3.3', 'Switched memory B-cell': '0.0', 'Exhausted memory B-cell': '0.7', 'Progenitor cell': '2.3', 'Memory T-reg': '1.3', 'Naive CD4 T-cell activated': '0.3', 'Naive CD8 T-cell activated': '0.6', 'Naive T-reg': '0.1'}
1O6S, 2O72, 2OMT, 2OMU, 2OMV, 2OMX, 2OMY, 2OMZ, 3FF7, 3FF8, 3L6X, 3L6Y, 4ZT1, 4ZTE, 6CXY, 6OLE, 6OLF, 6OLG, 6VEL, 7STZ, 8H62
{'Adipose Tissue': 1.2125261088039867, 'Adrenal Gland': 0.1914223992248062, 'Bladder': 39.2033519047619, 'Blood': 1.340954264800861, 'Blood Vessel': 0.3121561692883895, 'Brain': 0.8550442199091597, 'Breast': 38.54918344226579, 'Cervix Uteri': 23.539115789473684, 'Colon': 43.41292142490372, 'Esophagus': 53.97513367404844, 'Fallopian Tube': 14.900277777777776, 'Heart': 0.119140469221835, 'Kidney': 25.040449438202245, 'Liver': 26.60802654867257, 'Lung': 35.447986366782004, 'Muscle': 0.1378936151930261, 'Nerve': 17.518468982229404, 'Ovary': 3.6515122222222223, 'Pancreas': 56.89676829268293, 'Pituitary': 24.68741660777385, 'Prostate': 61.279967346938776, 'Salivary Gland': 92.01685185185184, 'Skin': 79.77571720232172, 'Small Intestine': 71.7519320855615, 'Spleen': 10.061029045643156, 'Stomach': 58.07813805013927, 'Testis': 0.8144204986149585, 'Thyroid': 135.176797856049, 'Uterus': 1.442593943661972, 'Vagina': 86.52345512820513}
FZR1
MDQDYERRLLRQIVIQNENTMPRVTEMRRTLTPASSPVSSPSKHGDRFIPSRAGANWSVNFHRINENEKSPSQNRKAKDATSDNGKDGLAYSALLKNELLGAGIEKVQDPQTEDRRLQPSTPEKKGLFTYSLSTKRSSPDDGNDVSPYSLSPVSNKSQKLLRSPRKPTRKISKIPFKVLDAPELQDDFYLNLVDWSSLNVLSVGLGTCVYLWSACTSQVTRLCDLSVEGDSVTSVGWSERGNLVAVGTHKGFVQIWDAAAGKKLSMLEGHTARVGALAWNAEQLSSGSRDRMILQRDIRTPPLQSERRLQGHRQEVCGLKWSTDHQLLASGGNDNKLLVWNHSSLSPVQQYTEHLAAVKAIAWSPHQHGLLASGGGTADRCIRFWNTLTGQPLQCIDTGSQVCNLAWSKHANELVSTHGYSQNQILVWKYPSLTQVAKLTGHSYRVLYLAMSPDGEAIVTGAGDETLRFWNVFSKTRSTKESVSVLNLFTRIR
Homo sapiens
Nucleus
Not found
{}
null
{'Adipose Tissue': 19.46810880398671, 'Adrenal Gland': 29.2876007751938, 'Bladder': 27.38285714285714, 'Blood': 19.547019375672768, 'Blood Vessel': 27.599573033707863, 'Brain': 26.95018433005299, 'Breast': 26.63632897603486, 'Cervix Uteri': 40.770526315789475, 'Colon': 23.282314505776636, 'Esophagus': 23.994503806228373, 'Fallopian Tube': 34.57222222222222, 'Heart': 8.733104529616725, 'Kidney': 17.97647191011236, 'Liver': 14.69487168141593, 'Lung': 26.58581314878893, 'Muscle': 11.545407222914072, 'Nerve': 34.77274636510501, 'Ovary': 42.36077777777778, 'Pancreas': 10.27298475609756, 'Pituitary': 58.10975265017668, 'Prostate': 34.24644897959183, 'Salivary Gland': 25.609259259259257, 'Skin': 32.51415257048093, 'Small Intestine': 25.308288770053473, 'Spleen': 28.76311203319502, 'Stomach': 17.90639554317549, 'Testis': 69.12493074792243, 'Thyroid': 48.03656814701378, 'Uterus': 41.83204225352112, 'Vagina': 35.41961538461538}
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0.76, 0.55, 0.31, 0.94, 0.22, 0.57, 0.17, 0.4, 0.07, 0.5, 0.31, 0.7, 0.2, 0.14, 0.3, 0.23, 0.58, 0.07, 0.06, 0.55, 0.15, 0.46, 0.43, 0.64, 0.53, 0.0, 0.18, 0.01, 0.23, 0.02, 0.63, 0.33, 0.79, 0.06, 0.38, 0.07, 0.14, 0.23, 0.68, 0.89, 0.29, 0.06, 0.72, 0.92, 0.24, 0.25, 0.0, 0.46, 0.02, 0.21, 0.01, 0.06, 0.0, 0.05, 0.07, 0.61, 0.17, 0.89, 0.72, 0.66, 0.14, 0.52, 0.07, 0.58, 0.01, 0.26, 0.0, 0.13, 0.0, 0.29, 0.04, 0.46, 0.27, 0.28, 0.23, 0.56, 0.32, 0.25, 0.0, 0.33, 0.05, 0.55, 0.5, 0.58, 0.53, 0.04, 0.27, 0.02, 0.04, 0.37, 0.67, 0.74, 0.35, 0.62, 0.54, 0.26, 0.46, 0.0, 0.47, 0.09, 0.45, 0.15, 0.39, 0.05, 0.44, 0.85, 0.56, 0.11, 0.11, 0.35, 0.42, 0.03, 0.32, 0.12, 0.49, 0.19, 0.25, 0.8, 0.6, 0.09, 0.49, 0.57, 0.36, 0.04, 0.35, 0.28, 0.52, 0.39, 0.5, 0.28, 0.93, 0.47, 0.3, 0.47, 0.08, 0.02, 0.18, 0.01, 0.34, 0.23, 0.55, 0.57, 0.91, 0.1, 0.78, 0.52, 0.34, 0.61, 0.24, 0.75, 0.0, 0.2, 0.02, 0.24, 0.0, 0.18, 0.04, 0.44, 0.59, 0.71, 0.29, 0.52, 0.37, 0.5, 0.11, 0.6, 0.02, 0.48, 0.01, 0.16, 0.04, 0.35, 0.66, 0.47, 0.74, 0.14, 0.62, 0.16, 0.77, 0.79, 0.27, 0.93, 0.69, 0.88, 0.88, 0.85, 0.87, 0.91, 0.92, 0.82, 0.63, 0.75, 0.7, 0.7, 0.38, 0.43, 0.64, 0.55, 0.54, 0.59, 0.45, 0.47, 0.5, 0.58, 0.52, 0.61, 0.57, 0.52, 0.68, 0.44, 0.6, 0.61, 0.58, 0.55, 0.5, 0.61, 0.61, 0.86, 0.86, 0.75, 0.91, 0.96, 0.93, 1.0, 0.87, 0.97, 0.91, 0.95, 0.86, 0.98, 0.93, 0.88, 0.59, 0.87, 0.7, 0.67, 0.85, 0.89, 0.88, 0.91, 0.93, 0.88, 0.99, 0.92, 1.0, 0.79, 0.9, 1.0, 0.94, 1.0, 0.97, 0.96, 0.9, 0.63, 0.68, 0.48, 0.54, 0.8, 0.7, 0.7, 0.95, 0.87, 0.77, 0.84, 0.79, 0.89, 0.95, 0.8, 0.77, 0.51, 0.87, 0.7, 0.52, 0.84, 0.91, 0.51, 0.96, 0.79, 0.92, 0.84, 0.21, 0.89, 0.53, 0.52, 0.89, 0.86, 0.26, 0.91, 0.45, 0.68, 0.84, 0.48, 0.44, 0.51, 0.62, 0.28, 0.59, 0.63, 0.57, 0.15, 0.55, 0.66, 0.1, 0.38, 0.74, 0.65, 0.17, 0.43, 0.66, 0.41, 0.8, 0.75, 0.9, 0.93, 0.52, 0.76, 0.89, 0.87, 0.76, 0.92, 0.91, 0.75, 0.61, 0.96, 0.89, 0.73, 0.97, 0.68, 0.87, 0.55, 0.85, 0.77, 0.69, 0.76, 0.98, 0.83, 0.68, 0.82, 0.74, 0.65, 0.96, 0.93, 0.54, 0.64, 0.28, 0.54, 0.52, 0.16, 0.51, 0.88, 0.6, 0.4, 0.88, 0.95, 0.33, 0.56, 0.73, 0.39, 0.06, 0.61, 0.75, 0.47, 0.19, 0.87, 0.7, 0.97, 0.94, 0.97]
null
null
null
Component of an E-cadherin/ catenin adhesion complex composed of at least E-cadherin/CDH1, beta-catenin/CTNNB1 or gamma-catenin/JUP, and potentially alpha-catenin/CTNNA1. Forms a ternary complex composed of ADAM10, CADH1 and EPHA4,
null
null
KLRG1, SPEF1, DLGAP5, AJAP1, RAPGEF2, RAB8B, PIP5K1C, PKP2, TRPV4, CTNNB1, CAV1, DDR1, TBC1D2, CTNNA1, JUP, CTNND1, PSEN1, LIMA1, CDH1, JUP, ADAM10, CADH1 , EPHA4,
null
null
null
null
Homodimer
null
79.91949
0.474025
null
null
1,605
P12830
Q9UM13
null
degron_data
CDH1
MGPWSRSLSALLLLLQVSSWLCQEPEPCHPGFDAESYTFTVPRRHLERGRVLGRVNFEDCTGRQRTAYFSLDTRFKVGTDGVITVKRPLRFHNPQIHFLVYAWDSTYRKFSTKVTLNTVGHHHRPPPHQASVSGIQAELLTFPNSSPGLRRQKRDWVIPPISCPENEKGPFPKNLVQIKSNKDKEGKVFYSITGQGADTPPVGVFIIERETGWLKVTEPLDRERIATYTLFSHAVSSNGNAVEDPMEILITVTDQNDNKPEFTQEVFKGSVMEGALPGTSVMEVTATDADDDVNTYNAAIAYTILSQDPELPDKNMFTINRNTGVISVVTTGLDRESFPTYTLVVQAADLQGEGLSTTATAVITVTDTNDNPPIFNPTTYKGQVPENEANVVITTLKVTDADAPNTPAWEAVYTILNDDGGQFVVTTNPVNNDGILKTAKGLDFEAKQQYILHVAVTNVVPFEVSLTTSTATVTVDVLDVNEAPIFVPPEKRVEVSEDFGVGQEITSYTAQEPDTFMEQKITYRIWRDTANWLEINPDTGAISTRAELDREDFEHVKNSTYTALIIATDNGSPVATGTGTLLLILSDVNDNAPIPEPRTIFFCERNPKPQVINIIDADLPPNTSPFTAELTHGASANWTIQYNDPTQESIILKPKMALEVGDYKINLKLMDNQNKDQVTTLEVSVCDCEGAAGVCRKAQPVEAGLQIPAILGILGGILALLILILLLLLFLRRRAVVKEPLLPPEDDTRDNVYYYDEEGGGEEDQDFDLSQLHRGLDARPEVTRNDVAPTLMSVPRYLPRPANPDEIGNFIDENLKAADTDPTAPPYDSLLVFDYEGSGSEAASLSSLNSSESDKDQDYDYLNEWGNRFKKLADMYGGGEDD
Homo sapiens
Cell junction, adherens junction, Cell membrane, Endosome, Golgi apparatus, trans-Golgi network, Cytoplasm, Cell junction, desmosome
Tissue enhanced (parathyroid)
{'Ciliated cells': '119.1', 'Basal respiratory cells': '71.1', 'Club cells': '97.3', 'Ionocytes': '81.0', 'Mucus glandular cells': '155.0', 'Serous glandular cells': '67.8', 'Gastric mucus-secreting cells': '133.2', 'Proximal enterocytes': '140.9', 'Paneth cells': '125.1', 'Distal enterocytes': '307.5', 'Intestinal goblet cells': '173.5', 'Exocrine glandular cells': '-0.605', 'Basal prostatic cells': '68.3', 'Prostatic glandular cells': '186.7', 'Breast glandular cells': '0.773', 'Breast myoepithelial cells': '0.700', 'Glandular and luminal cells': '313.0', 'Secretory cells': '82.3', 'Basal keratinocytes': '102.5', 'Suprabasal keratinocytes': '162.6', 'Basal squamous epithelial cells': '51.0', 'Squamous epithelial cells': '106.9', 'Alveolar cells type 1': '0.437', 'Alveolar cells type 2': '0.706', 'Salivary duct cells': '95.9', 'Ductal cells': '0.541', 'Hepatocytes': '0.600', 'Cholangiocytes': '129.7', 'Proximal tubular cells': '0.042', 'Distal tubular cells': '0.0', 'Collecting duct cells': '143.9', 'Mesothelial cells': '0.799', 'Sertoli cells': '0.252', 'Granulosa cells': '12.9', 'Enteroendocrine cells': '92.4', 'Pancreatic endocrine cells': '78.1', 'Leydig cells': '0.264', 'Excitatory neurons': '0.7', 'Inhibitory neurons': '1.3', 'Cone photoreceptor cells': '0.0', 'Rod photoreceptor cells': '0.0', 'Bipolar cells': '0.2', 'Horizontal cells': '0.6', 'Astrocytes': '0.6', 'Oligodendrocyte precursor cells': '0.5', 'Oligodendrocytes': '29.9', 'Microglial cells': '0.9', 'Muller glia cells': '0.1', 'Schwann cells': '0.131', 'Spermatogonia': '0.392', 'Spermatocytes': '0.193', 'Early spermatids': '-0.217', 'Late spermatids': '-0.290', 'Oocytes': '16.9', 'Cytotrophoblasts': '119.2', 'Syncytiotrophoblasts': '45.0', 'Extravillous trophoblasts': '24.9', 'Endothelial cells': '6.1', 'Lymphatic endothelial cells': '0.4', 'Cardiomyocytes': '0.135', 'Skeletal myocytes': '0.107', 'Smooth muscle cells': '5.8', 'Adipocytes': '2.1', 'Melanocytes': '0.335', 'Fibroblasts': '6.5', 'Peritubular cells': '0.210', 'Endometrial stromal cells': '27.7', 'Ovarian stromal cells': '0.7', 'Undifferentiated cells': '101.6', 'T-cells': '2.9', 'B-cells': '4.4', 'Plasma cells': '6.1', 'Nk-cells': '0.0', 'Granulocytes': '8.4', 'Monocytes': '0.0', 'Macrophages': '6.0', 'Hofbauer cells': '4.3', 'Kupffer cells': '1.0', 'Dendritic cells': '5.9', 'Langerhans cells': '0.304', 'Erythroid cells': '0.036', 'Adipocytes (Subcutaneous)': '-0.081', 'Adipocytes (Visceral)': '-0.209', 'Breast glandular cells (progenitors)': '0.538', 'Adipocytes (Breast)': '-0.689', 'Colon enterocytes': '0.790', 'Colon enteroendocrine cells': '0.112', 'Enteric glia cells': '-0.048', 'Mitotic cells (Colon)': '0.299', 'Mitotic cells (Heart)': '0.120', 'Podocytes': '-0.118', 'Ascending Loop of Henle cells': '0.475', 'Intercalated cells': '0.212', 'Cholangiocyte': '0.090', 'NK-cells (Liver)': '-0.005', 'Respiratory ciliated cells': '-0.012', 'Mitotic cells (Lung)': '0.071', 'NK-cells (Lung)': '-0.266', 'B-cells (Lung)': '-0.296', 'Alpha cells': '0.270', 'Beta cells': '0.152', 'Prostate glandular cells': '0.764', 'Prostate basal glandular cells': '0.540', 'Urothelial cells': '0.205', 'Keratinocyte (other)': '0.510', 'Keratinocyte (granular)': '0.055', 'Hair cortex cells': '0.080', 'Inner root sheath cells': '0.131', 'Outer root sheath cells': '0.175', 'Sebaceous gland cells': '0.156', 'Eccrine sweat gland cells': '-0.207', 'Adipocytes (Skin)': '-0.244', 'Mitotic cells (Skin)': '0.442', 'Parietal cells': '0.654', 'Chief cells': '0.649', 'Gastric mucous cells': '0.781', 'Gastric enteroendocrine cells': '0.590', 'Mitotic cells (Stomach)': '0.445', 'Parafollicular cells': '0.173', 'Thyroid glandular cells': '0.865', 'Mitotic cells (Thyroid)': '-0.081', 'Adrenal cortex cells': '0.051', 'Adrenal medulla cells': '0.087', 'Mitotic cells (Adrenal gland)': '0.072', 'Minor salivary glandular cells': '0.371', 'Minor salivary gland ductal cells': '-0.142', 'Minor salivary gland basal cells': '0.582', 'Mitotic cells (Minor salivary gland)': '0.567', 'Adipocytes (Minor salivary gland)': '0.050', 'Somatotropes': '0.121', 'Lactotropes': '0.322', 'Gonadotropes': '0.330', 'Corticotropes': '0.180', 'Thyrotropes': '0.496', 'Undifferentiated cells (Pituitary gland)': '-0.108', 'Mitotic cells (Spleen)': '-0.228', 'Platelets': '-0.050', 'Erythrocytes': '-0.158', 'Hematopoietic stem cells': '-0.211', 'B-cells (Spleen)': '0.266', 'NK-cells (Spleen)': '0.309', 'Amygdala excitatory': '1.0', 'Cerebellar inhibitory': '0.9', 'Cge interneuron': '0.7', 'Deep-layer corticothalamic and 6b': '1.5', 'Deep-layer intratelencephalic': '0.7', 'Deep-layer near-projecting': '0.7', 'Eccentric medium spiny neuron': '0.6', 'Hippocampal ca1-3': '1.9', 'Hippocampal ca4': '1.2', 'Hippocampal dentate gyrus': '1.1', 'Lamp5-lhx6 and chandelier': '0.5', 'Lower rhombic lip': '0.8', 'Mammillary body': '0.6', 'Medium spiny neuron': '0.7', 'Mge interneuron': '1.7', 'Midbrain-derived inhibitory': '0.7', 'Miscellaneous': '0.9', 'Splatter': '3.8', 'Thalamic excitatory': '0.5', 'Upper rhombic lip': '0.8', 'Upper-layer intratelencephalic': '0.6', 'Astrocyte': '4.4', 'Bergmann glia': '0.2', 'Central nervous system macrophage': '0.6', 'Choroid plexus epithelial cell': '52.1', 'Committed oligodendrocyte precursor': '41.5', 'Ependymal cell': '4.8', 'Oligodendrocyte': '53.1', 'Oligodendrocyte precursor cell': '2.4', 'Endothelial cell': '0.7', 'Pericyte': '0.3', 'Vascular associated smooth muscle cell': '0.0', 'Fibroblast': '17.4', 'Leukocyte': '1.1', 'Basophil': '0.0', 'Eosinophil': '0.0', 'Neutrophil': '0.0', 'Classical monocyte': '0.0', 'Non-classical monocyte': '0.0', 'Intermediate monocyte': '0.0', 'T-reg': '2.3', 'GdT-cell': '0.0', 'MAIT T-cell': '0.0', 'Memory CD4 T-cell': '0.0', 'Naive CD4 T-cell': '0.1', 'Memory CD8 T-cell': '0.2', 'Naive CD8 T-cell': '0.3', 'Memory B-cell': '0.0', 'Naive B-cell': '0.1', 'Plasmacytoid DC': '46.6', 'Myeloid DC': '8.5', 'NK-cell': '0.1', 'Total PBMC': '0.7', 'Vd2 gdTCR': '0.0', 'Memory CD4 T-cell Th1\\/Th17': '0.1', 'Memory CD4 T-cell Th17': '0.2', 'Memory CD4 T-cell Th2': '2.9', 'Non-Vd2 gdTCR': '0.1', 'Memory CD4 T-cell Th1': '0.3', 'Memory CD4 T-cell TFH': '0.5', 'Terminal effector memory CD4 T-cell': '0.0', 'Central memory CD8 T-cell': '4.8', 'Effector memory CD8 T-cell': '0.0', 'Terminal effector memory CD8 T-cell': '0.6', 'Non-switched memory B-cell': '0.0', 'Plasmablast': '3.3', 'Switched memory B-cell': '0.0', 'Exhausted memory B-cell': '0.7', 'Progenitor cell': '2.3', 'Memory T-reg': '1.3', 'Naive CD4 T-cell activated': '0.3', 'Naive CD8 T-cell activated': '0.6', 'Naive T-reg': '0.1'}
1O6S, 2O72, 2OMT, 2OMU, 2OMV, 2OMX, 2OMY, 2OMZ, 3FF7, 3FF8, 3L6X, 3L6Y, 4ZT1, 4ZTE, 6CXY, 6OLE, 6OLF, 6OLG, 6VEL, 7STZ, 8H62
{'Adipose Tissue': 1.2125261088039867, 'Adrenal Gland': 0.1914223992248062, 'Bladder': 39.2033519047619, 'Blood': 1.340954264800861, 'Blood Vessel': 0.3121561692883895, 'Brain': 0.8550442199091597, 'Breast': 38.54918344226579, 'Cervix Uteri': 23.539115789473684, 'Colon': 43.41292142490372, 'Esophagus': 53.97513367404844, 'Fallopian Tube': 14.900277777777776, 'Heart': 0.119140469221835, 'Kidney': 25.040449438202245, 'Liver': 26.60802654867257, 'Lung': 35.447986366782004, 'Muscle': 0.1378936151930261, 'Nerve': 17.518468982229404, 'Ovary': 3.6515122222222223, 'Pancreas': 56.89676829268293, 'Pituitary': 24.68741660777385, 'Prostate': 61.279967346938776, 'Salivary Gland': 92.01685185185184, 'Skin': 79.77571720232172, 'Small Intestine': 71.7519320855615, 'Spleen': 10.061029045643156, 'Stomach': 58.07813805013927, 'Testis': 0.8144204986149585, 'Thyroid': 135.176797856049, 'Uterus': 1.442593943661972, 'Vagina': 86.52345512820513}
ANAPC10
MTTPNKTPPGADPKQLERTGTVREIGSQAVWSLSSCKPGFGVDQLRDDNLETYWQSDGSQPHLVNIQFRRKTTVKTLCIYADYKSDESYTPSKISVRVGNNFHNLQEIRQLELVEPSGWIHVPLTDNHKKPTRTFMIQIAVLANHQNGRDTHMRQIKIYTPVEESSIGKFPRCTTIDFMMYRSIR
Homo sapiens
null
Low tissue specificity
{'Ciliated cells': '23.3', 'Basal respiratory cells': '63.6', 'Club cells': '24.6', 'Ionocytes': '41.6', 'Mucus glandular cells': '10.1', 'Serous glandular cells': '11.3', 'Gastric mucus-secreting cells': '6.5', 'Proximal enterocytes': '16.3', 'Paneth cells': '14.1', 'Distal enterocytes': '8.3', 'Intestinal goblet cells': '15.9', 'Exocrine glandular cells': '-0.641', 'Basal prostatic cells': '16.9', 'Prostatic glandular cells': '11.2', 'Breast glandular cells': '0.466', 'Breast myoepithelial cells': '0.578', 'Glandular and luminal cells': '16.0', 'Secretory cells': '24.1', 'Basal keratinocytes': '16.0', 'Suprabasal keratinocytes': '18.3', 'Basal squamous epithelial cells': '11.1', 'Squamous epithelial cells': '12.7', 'Alveolar cells type 1': '0.043', 'Alveolar cells type 2': '-0.010', 'Salivary duct cells': '10.3', 'Ductal cells': '0.576', 'Hepatocytes': '0.285', 'Cholangiocytes': '7.6', 'Proximal tubular cells': '0.090', 'Distal tubular cells': '36.9', 'Collecting duct cells': '13.6', 'Mesothelial cells': '0.410', 'Sertoli cells': '-0.264', 'Granulosa cells': '25.4', 'Enteroendocrine cells': '15.1', 'Pancreatic endocrine cells': '28.9', 'Leydig cells': '-0.200', 'Excitatory neurons': '59.1', 'Inhibitory neurons': '55.6', 'Cone photoreceptor cells': '10.2', 'Rod photoreceptor cells': '5.9', 'Bipolar cells': '8.1', 'Horizontal cells': '5.7', 'Astrocytes': '29.7', 'Oligodendrocyte precursor cells': '52.4', 'Oligodendrocytes': '58.0', 'Microglial cells': '34.9', 'Muller glia cells': '17.4', 'Schwann cells': '0.136', 'Spermatogonia': '-0.015', 'Spermatocytes': '0.382', 'Early spermatids': '0.747', 'Late spermatids': '0.236', 'Oocytes': '59.6', 'Cytotrophoblasts': '40.1', 'Syncytiotrophoblasts': '31.4', 'Extravillous trophoblasts': '38.1', 'Endothelial cells': '20.4', 'Lymphatic endothelial cells': '23.5', 'Cardiomyocytes': '0.615', 'Skeletal myocytes': '-0.133', 'Smooth muscle cells': '21.3', 'Adipocytes': '26.8', 'Melanocytes': '0.159', 'Fibroblasts': '19.2', 'Peritubular cells': '-0.100', 'Endometrial stromal cells': '20.1', 'Ovarian stromal cells': '25.8', 'Undifferentiated cells': '17.7', 'T-cells': '15.6', 'B-cells': '15.6', 'Plasma cells': '11.1', 'Nk-cells': '19.1', 'Granulocytes': '20.1', 'Monocytes': '12.4', 'Macrophages': '15.8', 'Hofbauer cells': '33.7', 'Kupffer cells': '9.6', 'Dendritic cells': '14.7', 'Langerhans cells': '0.328', 'Erythroid cells': '0.149', 'Adipocytes (Subcutaneous)': '-0.399', 'Adipocytes (Visceral)': '-0.364', 'Breast glandular cells (progenitors)': '0.293', 'Adipocytes (Breast)': '-0.575', 'Colon enterocytes': '-0.268', 'Colon enteroendocrine cells': '0.318', 'Enteric glia cells': '0.451', 'Mitotic cells (Colon)': '-0.152', 'Mitotic cells (Heart)': '0.495', 'Podocytes': '0.129', 'Ascending Loop of Henle cells': '0.383', 'Intercalated cells': '0.142', 'Cholangiocyte': '0.410', 'NK-cells (Liver)': '-0.159', 'Respiratory ciliated cells': '0.022', 'Mitotic cells (Lung)': '0.091', 'NK-cells (Lung)': '-0.029', 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'Miscellaneous': '1.1', 'Splatter': '2.1', 'Thalamic excitatory': '1.7', 'Upper rhombic lip': '1.5', 'Upper-layer intratelencephalic': '0.8', 'Astrocyte': '1.1', 'Bergmann glia': '2.2', 'Central nervous system macrophage': '1.0', 'Choroid plexus epithelial cell': '1.0', 'Committed oligodendrocyte precursor': '1.4', 'Ependymal cell': '0.8', 'Oligodendrocyte': '1.3', 'Oligodendrocyte precursor cell': '1.9', 'Endothelial cell': '1.2', 'Pericyte': '0.9', 'Vascular associated smooth muscle cell': '0.7', 'Fibroblast': '1.3', 'Leukocyte': '0.9', 'Basophil': '20.7', 'Eosinophil': '9.7', 'Neutrophil': '4.1', 'Classical monocyte': '3.7', 'Non-classical monocyte': '7.0', 'Intermediate monocyte': '16.4', 'T-reg': '24.8', 'GdT-cell': '13.0', 'MAIT T-cell': '17.4', 'Memory CD4 T-cell': '13.6', 'Naive CD4 T-cell': '9.4', 'Memory CD8 T-cell': '13.2', 'Naive CD8 T-cell': '6.6', 'Memory B-cell': '15.2', 'Naive B-cell': '6.8', 'Plasmacytoid DC': '30.8', 'Myeloid DC': '16.6', 'NK-cell': '7.1', 'Total PBMC': '21.3', 'Vd2 gdTCR': '28.0', 'Memory CD4 T-cell Th1\\/Th17': '8.9', 'Memory CD4 T-cell Th17': '8.1', 'Memory CD4 T-cell Th2': '8.0', 'Non-Vd2 gdTCR': '26.5', 'Memory CD4 T-cell Th1': '7.5', 'Memory CD4 T-cell TFH': '7.2', 'Terminal effector memory CD4 T-cell': '15.0', 'Central memory CD8 T-cell': '20.8', 'Effector memory CD8 T-cell': '17.5', 'Terminal effector memory CD8 T-cell': '22.2', 'Non-switched memory B-cell': '16.2', 'Plasmablast': '20.1', 'Switched memory B-cell': '20.5', 'Exhausted memory B-cell': '20.6', 'Progenitor cell': '12.8', 'Memory T-reg': '6.6', 'Naive CD4 T-cell activated': '8.9', 'Naive CD8 T-cell activated': '10.6', 'Naive T-reg': '9.0'}
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0.32, 0.01, 0.22, 0.0, 0.05, 0.0, 0.41, 0.46, 0.42, 0.82, 0.48, 0.4, 0.5, 0.17, 0.62, 0.06, 0.32, 0.0, 0.25, 0.0, 0.42, 0.08, 0.41, 0.27, 0.16, 0.04, 0.36, 0.32, 0.2, 0.0, 0.52, 0.04, 0.66, 0.47, 0.52, 0.78, 0.09, 0.77, 0.08, 0.6, 0.0, 0.31, 0.03, 0.58, 0.47, 0.59, 0.44, 0.23, 0.54, 0.1, 0.18, 0.45, 0.0, 0.53, 0.11, 0.59, 0.17, 0.51, 0.01, 0.19, 0.71, 0.77, 0.3, 0.44, 0.08, 0.14, 0.52, 0.05, 0.37, 0.1, 0.42, 0.23, 0.61, 0.43, 0.22, 0.96, 0.54, 0.4, 0.3, 0.07, 0.39, 0.17, 0.43, 0.38, 0.3, 0.8, 0.83, 0.44, 0.03, 0.11, 0.0, 0.23, 0.0, 0.31, 0.0, 0.38, 0.58, 0.51, 0.01, 0.49, 0.13, 0.26, 0.69, 0.46, 0.41, 0.51, 0.06, 0.51, 0.03, 0.38, 0.0, 0.06, 0.0, 0.34, 0.08, 0.53, 0.42, 0.88, 0.25, 0.75, 0.49, 1.0, 0.34, 0.86, 0.48, 0.18, 0.52, 0.01, 0.32, 0.0, 0.19, 0.0, 0.3, 0.05, 0.44, 0.27, 0.43, 0.11, 0.31, 0.39, 0.03, 0.55, 0.04, 0.52, 0.51, 0.64, 0.57, 0.19, 0.68, 0.13, 0.84, 0.06, 0.31, 0.07, 0.69, 0.26, 0.37, 0.53, 0.67, 0.5, 0.56, 0.14, 0.18, 0.47, 0.01, 0.47, 0.15, 0.61, 0.28, 0.2, 0.02, 0.76, 0.55, 0.31, 0.94, 0.22, 0.57, 0.17, 0.4, 0.07, 0.5, 0.31, 0.7, 0.2, 0.14, 0.3, 0.23, 0.58, 0.07, 0.06, 0.55, 0.15, 0.46, 0.43, 0.64, 0.53, 0.0, 0.18, 0.01, 0.23, 0.02, 0.63, 0.33, 0.79, 0.06, 0.38, 0.07, 0.14, 0.23, 0.68, 0.89, 0.29, 0.06, 0.72, 0.92, 0.24, 0.25, 0.0, 0.46, 0.02, 0.21, 0.01, 0.06, 0.0, 0.05, 0.07, 0.61, 0.17, 0.89, 0.72, 0.66, 0.14, 0.52, 0.07, 0.58, 0.01, 0.26, 0.0, 0.13, 0.0, 0.29, 0.04, 0.46, 0.27, 0.28, 0.23, 0.56, 0.32, 0.25, 0.0, 0.33, 0.05, 0.55, 0.5, 0.58, 0.53, 0.04, 0.27, 0.02, 0.04, 0.37, 0.67, 0.74, 0.35, 0.62, 0.54, 0.26, 0.46, 0.0, 0.47, 0.09, 0.45, 0.15, 0.39, 0.05, 0.44, 0.85, 0.56, 0.11, 0.11, 0.35, 0.42, 0.03, 0.32, 0.12, 0.49, 0.19, 0.25, 0.8, 0.6, 0.09, 0.49, 0.57, 0.36, 0.04, 0.35, 0.28, 0.52, 0.39, 0.5, 0.28, 0.93, 0.47, 0.3, 0.47, 0.08, 0.02, 0.18, 0.01, 0.34, 0.23, 0.55, 0.57, 0.91, 0.1, 0.78, 0.52, 0.34, 0.61, 0.24, 0.75, 0.0, 0.2, 0.02, 0.24, 0.0, 0.18, 0.04, 0.44, 0.59, 0.71, 0.29, 0.52, 0.37, 0.5, 0.11, 0.6, 0.02, 0.48, 0.01, 0.16, 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[47.3, 62.96, 65.72, 71.78, 83.68, 87.89, 88.76, 91.23, 92.29, 91.32, 92.42, 92.39, 91.33, 90.49, 90.76, 88.91, 89.49, 89.88, 89.34, 87.57, 88.38, 92.2, 93.32, 94.33, 95.16, 93.64, 92.79, 93.23, 95.67, 96.4, 97.06, 95.92, 96.66, 95.05, 95.14, 93.42, 93.18, 92.14, 93.47, 94.05, 94.13, 94.21, 93.99, 93.62, 93.18, 93.75, 93.45, 93.64, 93.65, 93.77, 93.91, 95.41, 96.72, 96.6, 96.52, 96.11, 93.95, 92.16, 93.84, 92.6, 96.33, 97.13, 97.24, 97.55, 97.42, 97.1, 96.77, 96.14, 92.21, 94.25, 93.86, 94.79, 94.78, 95.13, 93.62, 94.36, 95.85, 96.42, 96.34, 97.02, 95.82, 95.57, 94.63, 93.7, 93.86, 93.99, 93.89, 95.52, 95.79, 96.49, 96.94, 95.97, 96.97, 97.54, 97.23, 97.09, 96.78, 96.1, 94.76, 93.79, 90.35, 92.39, 91.49, 94.06, 94.66, 94.48, 94.68, 93.52, 93.62, 95.31, 95.33, 95.86, 94.56, 94.88, 93.89, 94.96, 94.45, 95.34, 96.62, 96.3, 95.12, 95.18, 93.96, 92.48, 88.25, 82.45, 82.1, 85.98, 85.01, 89.51, 91.51, 92.83, 93.94, 95.03, 96.22, 96.31, 96.95, 97.65, 97.62, 97.56, 97.59, 96.96, 96.72, 96.05, 93.83, 93.04, 91.08, 92.5, 93.87, 94.81, 96.16, 97.18, 95.06, 95.83, 96.28, 96.89, 96.49, 96.08, 95.81, 94.05, 91.96, 86.96, 69.94, 55.42, 48.84, 46.52, 51.68, 58.18, 61.09, 58.8, 59.83, 64.75, 64.33, 76.1, 82.31, 83.64, 84.04, 79.99, 80.47, 82.93, 81.59, 75.89, 75.27, 81.59, 76.05]
[0.97, 0.92, 0.38, 0.94, 0.79, 0.48, 0.24, 0.86, 0.67, 0.37, 0.55, 0.42, 0.01, 0.48, 0.57, 0.28, 0.32, 0.81, 0.55, 0.47, 0.37, 0.08, 0.65, 0.25, 0.02, 0.04, 0.81, 0.43, 0.16, 0.64, 0.14, 0.38, 0.18, 0.49, 0.19, 0.57, 0.35, 0.89, 0.67, 0.32, 0.13, 0.28, 0.77, 0.24, 0.0, 0.29, 0.46, 0.54, 0.38, 0.36, 0.76, 0.28, 0.24, 0.0, 0.09, 0.0, 0.52, 0.3, 0.81, 0.48, 0.41, 0.0, 0.21, 0.0, 0.07, 0.0, 0.36, 0.06, 0.92, 0.7, 0.45, 0.11, 0.31, 0.0, 0.39, 0.15, 0.0, 0.0, 0.0, 0.17, 0.02, 0.16, 0.21, 0.83, 0.65, 0.04, 0.56, 0.29, 0.35, 0.01, 0.01, 0.11, 0.33, 0.0, 0.0, 0.0, 0.24, 0.1, 0.11, 0.57, 0.46, 0.48, 0.93, 0.37, 0.22, 0.72, 0.52, 0.33, 0.48, 0.53, 0.22, 0.64, 0.04, 0.42, 0.17, 0.01, 0.44, 0.09, 0.09, 0.09, 0.34, 0.01, 0.52, 0.0, 0.28, 0.37, 0.97, 0.79, 0.83, 0.66, 0.33, 0.14, 0.64, 0.02, 0.32, 0.02, 0.0, 0.06, 0.0, 0.0, 0.01, 0.29, 0.33, 0.05, 0.14, 0.68, 0.91, 0.09, 0.73, 0.15, 0.0, 0.08, 0.0, 0.1, 0.01, 0.0, 0.08, 0.0, 0.0, 0.19, 0.33, 0.33, 0.84, 0.5, 0.51, 0.52, 0.33, 0.7, 0.98, 0.76, 0.85, 0.61, 0.18, 0.74, 0.58, 0.8, 0.68, 0.54, 0.4, 0.78, 0.86, 0.59, 0.75, 1.0, 0.95]
null
Component of an E-cadherin/ catenin adhesion complex composed of at least E-cadherin/CDH1, beta-catenin/CTNNB1 or gamma-catenin/JUP, and potentially alpha-catenin/CTNNA1. Forms a ternary complex composed of ADAM10, CADH1 and EPHA4,
null
null
KLRG1, SPEF1, DLGAP5, AJAP1, RAPGEF2, RAB8B, PIP5K1C, PKP2, TRPV4, CTNNB1, CAV1, DDR1, TBC1D2, CTNNA1, JUP, CTNND1, PSEN1, LIMA1, CDH1, JUP, ADAM10, CADH1 , EPHA4,
null
null
null
null
Homodimer
null
79.91949
0.474025
90.246108
0.367784
2,792
P12830
Q9Y2I6
null
degron_data
CDH1
MGPWSRSLSALLLLLQVSSWLCQEPEPCHPGFDAESYTFTVPRRHLERGRVLGRVNFEDCTGRQRTAYFSLDTRFKVGTDGVITVKRPLRFHNPQIHFLVYAWDSTYRKFSTKVTLNTVGHHHRPPPHQASVSGIQAELLTFPNSSPGLRRQKRDWVIPPISCPENEKGPFPKNLVQIKSNKDKEGKVFYSITGQGADTPPVGVFIIERETGWLKVTEPLDRERIATYTLFSHAVSSNGNAVEDPMEILITVTDQNDNKPEFTQEVFKGSVMEGALPGTSVMEVTATDADDDVNTYNAAIAYTILSQDPELPDKNMFTINRNTGVISVVTTGLDRESFPTYTLVVQAADLQGEGLSTTATAVITVTDTNDNPPIFNPTTYKGQVPENEANVVITTLKVTDADAPNTPAWEAVYTILNDDGGQFVVTTNPVNNDGILKTAKGLDFEAKQQYILHVAVTNVVPFEVSLTTSTATVTVDVLDVNEAPIFVPPEKRVEVSEDFGVGQEITSYTAQEPDTFMEQKITYRIWRDTANWLEINPDTGAISTRAELDREDFEHVKNSTYTALIIATDNGSPVATGTGTLLLILSDVNDNAPIPEPRTIFFCERNPKPQVINIIDADLPPNTSPFTAELTHGASANWTIQYNDPTQESIILKPKMALEVGDYKINLKLMDNQNKDQVTTLEVSVCDCEGAAGVCRKAQPVEAGLQIPAILGILGGILALLILILLLLLFLRRRAVVKEPLLPPEDDTRDNVYYYDEEGGGEEDQDFDLSQLHRGLDARPEVTRNDVAPTLMSVPRYLPRPANPDEIGNFIDENLKAADTDPTAPPYDSLLVFDYEGSGSEAASLSSLNSSESDKDQDYDYLNEWGNRFKKLADMYGGGEDD
Homo sapiens
Cell junction, adherens junction, Cell membrane, Endosome, Golgi apparatus, trans-Golgi network, Cytoplasm, Cell junction, desmosome
Tissue enhanced (parathyroid)
{'Ciliated cells': '119.1', 'Basal respiratory cells': '71.1', 'Club cells': '97.3', 'Ionocytes': '81.0', 'Mucus glandular cells': '155.0', 'Serous glandular cells': '67.8', 'Gastric mucus-secreting cells': '133.2', 'Proximal enterocytes': '140.9', 'Paneth cells': '125.1', 'Distal enterocytes': '307.5', 'Intestinal goblet cells': '173.5', 'Exocrine glandular cells': '-0.605', 'Basal prostatic cells': '68.3', 'Prostatic glandular cells': '186.7', 'Breast glandular cells': '0.773', 'Breast myoepithelial cells': '0.700', 'Glandular and luminal cells': '313.0', 'Secretory cells': '82.3', 'Basal keratinocytes': '102.5', 'Suprabasal keratinocytes': '162.6', 'Basal squamous epithelial cells': '51.0', 'Squamous epithelial cells': '106.9', 'Alveolar cells type 1': '0.437', 'Alveolar cells type 2': '0.706', 'Salivary duct cells': '95.9', 'Ductal cells': '0.541', 'Hepatocytes': '0.600', 'Cholangiocytes': '129.7', 'Proximal tubular cells': '0.042', 'Distal tubular cells': '0.0', 'Collecting duct cells': '143.9', 'Mesothelial cells': '0.799', 'Sertoli cells': '0.252', 'Granulosa cells': '12.9', 'Enteroendocrine cells': '92.4', 'Pancreatic endocrine cells': '78.1', 'Leydig cells': '0.264', 'Excitatory neurons': '0.7', 'Inhibitory neurons': '1.3', 'Cone photoreceptor cells': '0.0', 'Rod photoreceptor cells': '0.0', 'Bipolar cells': '0.2', 'Horizontal cells': '0.6', 'Astrocytes': '0.6', 'Oligodendrocyte precursor cells': '0.5', 'Oligodendrocytes': '29.9', 'Microglial cells': '0.9', 'Muller glia cells': '0.1', 'Schwann cells': '0.131', 'Spermatogonia': '0.392', 'Spermatocytes': '0.193', 'Early spermatids': '-0.217', 'Late spermatids': '-0.290', 'Oocytes': '16.9', 'Cytotrophoblasts': '119.2', 'Syncytiotrophoblasts': '45.0', 'Extravillous trophoblasts': '24.9', 'Endothelial cells': '6.1', 'Lymphatic endothelial cells': '0.4', 'Cardiomyocytes': '0.135', 'Skeletal myocytes': '0.107', 'Smooth muscle cells': '5.8', 'Adipocytes': '2.1', 'Melanocytes': '0.335', 'Fibroblasts': '6.5', 'Peritubular cells': '0.210', 'Endometrial stromal cells': '27.7', 'Ovarian stromal cells': '0.7', 'Undifferentiated cells': '101.6', 'T-cells': '2.9', 'B-cells': '4.4', 'Plasma cells': '6.1', 'Nk-cells': '0.0', 'Granulocytes': '8.4', 'Monocytes': '0.0', 'Macrophages': '6.0', 'Hofbauer cells': '4.3', 'Kupffer cells': '1.0', 'Dendritic cells': '5.9', 'Langerhans cells': '0.304', 'Erythroid cells': '0.036', 'Adipocytes (Subcutaneous)': '-0.081', 'Adipocytes (Visceral)': '-0.209', 'Breast glandular cells (progenitors)': '0.538', 'Adipocytes (Breast)': '-0.689', 'Colon enterocytes': '0.790', 'Colon enteroendocrine cells': '0.112', 'Enteric glia cells': '-0.048', 'Mitotic cells (Colon)': '0.299', 'Mitotic cells (Heart)': '0.120', 'Podocytes': '-0.118', 'Ascending Loop of Henle cells': '0.475', 'Intercalated cells': '0.212', 'Cholangiocyte': '0.090', 'NK-cells (Liver)': '-0.005', 'Respiratory ciliated cells': '-0.012', 'Mitotic cells (Lung)': '0.071', 'NK-cells (Lung)': '-0.266', 'B-cells (Lung)': '-0.296', 'Alpha cells': '0.270', 'Beta cells': '0.152', 'Prostate glandular cells': '0.764', 'Prostate basal glandular cells': '0.540', 'Urothelial cells': '0.205', 'Keratinocyte (other)': '0.510', 'Keratinocyte (granular)': '0.055', 'Hair cortex cells': '0.080', 'Inner root sheath cells': '0.131', 'Outer root sheath cells': '0.175', 'Sebaceous gland cells': '0.156', 'Eccrine sweat gland cells': '-0.207', 'Adipocytes (Skin)': '-0.244', 'Mitotic cells (Skin)': '0.442', 'Parietal cells': '0.654', 'Chief cells': '0.649', 'Gastric mucous cells': '0.781', 'Gastric enteroendocrine cells': '0.590', 'Mitotic cells (Stomach)': '0.445', 'Parafollicular cells': '0.173', 'Thyroid glandular cells': '0.865', 'Mitotic cells (Thyroid)': '-0.081', 'Adrenal cortex cells': '0.051', 'Adrenal medulla cells': '0.087', 'Mitotic cells (Adrenal gland)': '0.072', 'Minor salivary glandular cells': '0.371', 'Minor salivary gland ductal cells': '-0.142', 'Minor salivary gland basal cells': '0.582', 'Mitotic cells (Minor salivary gland)': '0.567', 'Adipocytes (Minor salivary gland)': '0.050', 'Somatotropes': '0.121', 'Lactotropes': '0.322', 'Gonadotropes': '0.330', 'Corticotropes': '0.180', 'Thyrotropes': '0.496', 'Undifferentiated cells (Pituitary gland)': '-0.108', 'Mitotic cells (Spleen)': '-0.228', 'Platelets': '-0.050', 'Erythrocytes': '-0.158', 'Hematopoietic stem cells': '-0.211', 'B-cells (Spleen)': '0.266', 'NK-cells (Spleen)': '0.309', 'Amygdala excitatory': '1.0', 'Cerebellar inhibitory': '0.9', 'Cge interneuron': '0.7', 'Deep-layer corticothalamic and 6b': '1.5', 'Deep-layer intratelencephalic': '0.7', 'Deep-layer near-projecting': '0.7', 'Eccentric medium spiny neuron': '0.6', 'Hippocampal ca1-3': '1.9', 'Hippocampal ca4': '1.2', 'Hippocampal dentate gyrus': '1.1', 'Lamp5-lhx6 and chandelier': '0.5', 'Lower rhombic lip': '0.8', 'Mammillary body': '0.6', 'Medium spiny neuron': '0.7', 'Mge interneuron': '1.7', 'Midbrain-derived inhibitory': '0.7', 'Miscellaneous': '0.9', 'Splatter': '3.8', 'Thalamic excitatory': '0.5', 'Upper rhombic lip': '0.8', 'Upper-layer intratelencephalic': '0.6', 'Astrocyte': '4.4', 'Bergmann glia': '0.2', 'Central nervous system macrophage': '0.6', 'Choroid plexus epithelial cell': '52.1', 'Committed oligodendrocyte precursor': '41.5', 'Ependymal cell': '4.8', 'Oligodendrocyte': '53.1', 'Oligodendrocyte precursor cell': '2.4', 'Endothelial cell': '0.7', 'Pericyte': '0.3', 'Vascular associated smooth muscle cell': '0.0', 'Fibroblast': '17.4', 'Leukocyte': '1.1', 'Basophil': '0.0', 'Eosinophil': '0.0', 'Neutrophil': '0.0', 'Classical monocyte': '0.0', 'Non-classical monocyte': '0.0', 'Intermediate monocyte': '0.0', 'T-reg': '2.3', 'GdT-cell': '0.0', 'MAIT T-cell': '0.0', 'Memory CD4 T-cell': '0.0', 'Naive CD4 T-cell': '0.1', 'Memory CD8 T-cell': '0.2', 'Naive CD8 T-cell': '0.3', 'Memory B-cell': '0.0', 'Naive B-cell': '0.1', 'Plasmacytoid DC': '46.6', 'Myeloid DC': '8.5', 'NK-cell': '0.1', 'Total PBMC': '0.7', 'Vd2 gdTCR': '0.0', 'Memory CD4 T-cell Th1\\/Th17': '0.1', 'Memory CD4 T-cell Th17': '0.2', 'Memory CD4 T-cell Th2': '2.9', 'Non-Vd2 gdTCR': '0.1', 'Memory CD4 T-cell Th1': '0.3', 'Memory CD4 T-cell TFH': '0.5', 'Terminal effector memory CD4 T-cell': '0.0', 'Central memory CD8 T-cell': '4.8', 'Effector memory CD8 T-cell': '0.0', 'Terminal effector memory CD8 T-cell': '0.6', 'Non-switched memory B-cell': '0.0', 'Plasmablast': '3.3', 'Switched memory B-cell': '0.0', 'Exhausted memory B-cell': '0.7', 'Progenitor cell': '2.3', 'Memory T-reg': '1.3', 'Naive CD4 T-cell activated': '0.3', 'Naive CD8 T-cell activated': '0.6', 'Naive T-reg': '0.1'}
1O6S, 2O72, 2OMT, 2OMU, 2OMV, 2OMX, 2OMY, 2OMZ, 3FF7, 3FF8, 3L6X, 3L6Y, 4ZT1, 4ZTE, 6CXY, 6OLE, 6OLF, 6OLG, 6VEL, 7STZ, 8H62
{'Adipose Tissue': 1.2125261088039867, 'Adrenal Gland': 0.1914223992248062, 'Bladder': 39.2033519047619, 'Blood': 1.340954264800861, 'Blood Vessel': 0.3121561692883895, 'Brain': 0.8550442199091597, 'Breast': 38.54918344226579, 'Cervix Uteri': 23.539115789473684, 'Colon': 43.41292142490372, 'Esophagus': 53.97513367404844, 'Fallopian Tube': 14.900277777777776, 'Heart': 0.119140469221835, 'Kidney': 25.040449438202245, 'Liver': 26.60802654867257, 'Lung': 35.447986366782004, 'Muscle': 0.1378936151930261, 'Nerve': 17.518468982229404, 'Ovary': 3.6515122222222223, 'Pancreas': 56.89676829268293, 'Pituitary': 24.68741660777385, 'Prostate': 61.279967346938776, 'Salivary Gland': 92.01685185185184, 'Skin': 79.77571720232172, 'Small Intestine': 71.7519320855615, 'Spleen': 10.061029045643156, 'Stomach': 58.07813805013927, 'Testis': 0.8144204986149585, 'Thyroid': 135.176797856049, 'Uterus': 1.442593943661972, 'Vagina': 86.52345512820513}
NINL
MDEEENHYVSQLREVYSSCDTTGTGFLDRQELTQLCLKLHLEQQLPVLLQTLLGNDHFARVNFEEFKEGFVAVLSSNAGVRPSDEDSSSLESAASSAIPPKYVNGSKWYGRRSRPELCDAATEARRVPEQQTQASLKSHLWRSASLESVESPKSDEEAESTKEAQNELFEAQGQLQTWDSEDFGSPQKSCSPSFDTPESQIRGVWEELGVGSSGHLSEQELAVVCQSVGLQGLEKEELEDLFNKLDQDGDGKVSLEEFQLGLFSHEPALLLESSTRVKPSKAWSHYQVPEESGCHTTTTSSLVSLCSSLRLFSSIDDGSGFAFPDQVLAMWTQEGIQNGREILQSLDFSVDEKVNLLELTWALDNELMTVDSAVQQAALACYHQELSYQQGQVEQLARERDKARQDLERAEKRNLEFVKEMDDCHSTLEQLTEKKIKHLEQGYRERLSLLRSEVEAERELFWEQAHRQRAALEWDVGRLQAEEAGLREKLTLALKENSRLQKEIVEVVEKLSDSERLALKLQKDLEFVLKDKLEPQSAELLAQEERFAAVLKEYELKCRDLQDRNDELQAELEGLWARLPKNRHSPSWSPDGRRRQLPGLGPAGISFLGNSAPVSIETELMMEQVKEHYQDLRTQLETKVNYYEREIAALKRNFEKERKDMEQARRREVSVLEGQKADLEELHEKSQEVIWGLQEQLQDTARGPEPEQMGLAPCCTQALCGLALRHHSHLQQIRREAEAELSGELSGLGALPARRDLTLELEEPPQGPLPRGSQRSEQLELERALKLQPCASEKRAQMCVSLALEEEELELARGKRVDGPSLEAEMQALPKDGLVAGSGQEGTRGLLPLRPGCGERPLAWLAPGDGRESEEAAGAGPRRRQAQDTEATQSPAPAPAPASHGPSERWSRMQPCGVDGDIVPKEPEPFGASAAGLEQPGARELPLLGTERDASQTQPRMWEPPLRPAASCRGQAERLQAIQEERARSWSRGTQEQASEQQARAEGALEPGCHKHSVEVARRGSLPSHLQLADPQGSWQEQLAAPEEGETKIALEREKDDMETKLLHLEDVVRALEKHVDLRENDRLEFHRLSEENTLLKNDLGRVRQELEAAESTHDAQRKEIEVLKKDKEKACSEMEVLNRQNQNYKDQLSQLNVRVLQLGQEASTHQAQNEEHRVTIQMLTQSLEEVVRSGQQQSDQIQKLRVELECLNQEHQSLQLPWSELTQTLEESQDQVQGAHLRLRQAQAQHLQEVRLVPQDRVAELHRLLSLQGEQARRRLDAQREEHEKQLKATEERVEEAEMILKNMEMLLQEKVDKLKEQFEKNTKSDLLLKELYVENAHLVRALQATEEKQRGAEKQSRLLEEKVRALNKLVSRIAPAALSV
Homo sapiens
Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, Cytoplasm
Low tissue specificity
{'Ciliated cells': '4.4', 'Basal respiratory cells': '2.8', 'Club cells': '3.5', 'Ionocytes': '3.3', 'Mucus glandular cells': '3.9', 'Serous glandular cells': '0.2', 'Gastric mucus-secreting cells': '4.1', 'Proximal enterocytes': '0.7', 'Paneth cells': '1.4', 'Distal enterocytes': '0.3', 'Intestinal goblet cells': '1.6', 'Exocrine glandular cells': '-0.424', 'Basal prostatic cells': '1.7', 'Prostatic glandular cells': '14.6', 'Breast glandular cells': '0.677', 'Breast myoepithelial cells': '0.568', 'Glandular and luminal cells': '2.7', 'Secretory cells': '1.2', 'Basal keratinocytes': '2.3', 'Suprabasal keratinocytes': '0.5', 'Basal squamous epithelial cells': '5.1', 'Squamous epithelial cells': '4.1', 'Alveolar cells type 1': '0.143', 'Alveolar cells type 2': '0.259', 'Salivary duct cells': '8.9', 'Ductal cells': '0.551', 'Hepatocytes': '0.596', 'Cholangiocytes': '17.2', 'Proximal tubular cells': '0.258', 'Distal tubular cells': '3.1', 'Collecting duct cells': '5.8', 'Mesothelial cells': '0.727', 'Sertoli cells': '0.719', 'Granulosa cells': '9.7', 'Enteroendocrine cells': '5.1', 'Pancreatic endocrine cells': '3.4', 'Leydig cells': '0.509', 'Excitatory neurons': '7.1', 'Inhibitory neurons': '31.2', 'Cone photoreceptor cells': '10.2', 'Rod photoreceptor cells': '1.9', 'Bipolar cells': '2.4', 'Horizontal cells': '7.6', 'Astrocytes': '40.3', 'Oligodendrocyte precursor cells': '44.3', 'Oligodendrocytes': '18.0', 'Microglial cells': '11.6', 'Muller glia cells': '2.1', 'Schwann cells': '0.016', 'Spermatogonia': '0.288', 'Spermatocytes': '-0.067', 'Early spermatids': '-0.566', 'Late spermatids': '-0.657', 'Oocytes': '0.7', 'Cytotrophoblasts': '2.8', 'Syncytiotrophoblasts': '1.3', 'Extravillous trophoblasts': '1.5', 'Endothelial cells': '2.9', 'Lymphatic endothelial cells': '16.0', 'Cardiomyocytes': '0.534', 'Skeletal myocytes': '0.587', 'Smooth muscle cells': '3.7', 'Adipocytes': '1.0', 'Melanocytes': '-0.017', 'Fibroblasts': '4.6', 'Peritubular cells': '0.553', 'Endometrial stromal cells': '6.3', 'Ovarian stromal cells': '13.1', 'Undifferentiated cells': '2.7', 'T-cells': '1.1', 'B-cells': '0.6', 'Plasma cells': '1.4', 'Nk-cells': '1.4', 'Granulocytes': '0.0', 'Monocytes': '0.0', 'Macrophages': '1.0', 'Hofbauer cells': '1.7', 'Kupffer cells': '2.8', 'Dendritic cells': '0.8', 'Langerhans cells': '0.095', 'Erythroid cells': '0.112', 'Adipocytes (Subcutaneous)': '-0.194', 'Adipocytes (Visceral)': '-0.270', 'Breast glandular cells (progenitors)': '0.466', 'Adipocytes (Breast)': '-0.492', 'Colon enterocytes': '-0.197', 'Colon enteroendocrine cells': '0.256', 'Enteric glia cells': '0.280', 'Mitotic cells (Colon)': '-0.217', 'Mitotic cells (Heart)': '0.202', 'Podocytes': '-0.126', 'Ascending Loop of Henle cells': '0.536', 'Intercalated cells': '0.050', 'Cholangiocyte': '-0.080', 'NK-cells (Liver)': '0.240', 'Respiratory ciliated cells': '0.070', 'Mitotic cells (Lung)': '0.074', 'NK-cells (Lung)': '-0.161', 'B-cells (Lung)': '-0.099', 'Alpha cells': '0.443', 'Beta cells': '0.374', 'Prostate glandular cells': '0.211', 'Prostate basal glandular cells': '0.274', 'Urothelial cells': '0.099', 'Keratinocyte (other)': '-0.387', 'Keratinocyte (granular)': '-0.459', 'Hair cortex cells': '0.314', 'Inner root sheath cells': '0.357', 'Outer root sheath cells': '0.650', 'Sebaceous gland cells': '0.290', 'Eccrine sweat gland cells': '0.408', 'Adipocytes (Skin)': '0.300', 'Mitotic cells (Skin)': '0.257', 'Parietal cells': '-0.475', 'Chief cells': '-0.550', 'Gastric mucous cells': '-0.337', 'Gastric enteroendocrine cells': '-0.388', 'Mitotic cells (Stomach)': '-0.073', 'Parafollicular cells': '0.102', 'Thyroid glandular cells': '0.286', 'Mitotic cells (Thyroid)': '-0.054', 'Adrenal cortex cells': '0.277', 'Adrenal medulla cells': '-0.051', 'Mitotic cells (Adrenal gland)': '0.198', 'Minor salivary glandular cells': '0.362', 'Minor salivary gland ductal cells': '0.352', 'Minor salivary gland basal cells': '0.375', 'Mitotic cells (Minor salivary gland)': '0.333', 'Adipocytes (Minor salivary gland)': '0.267', 'Somatotropes': '0.067', 'Lactotropes': '0.060', 'Gonadotropes': '0.199', 'Corticotropes': '-0.219', 'Thyrotropes': '0.140', 'Undifferentiated cells (Pituitary gland)': '0.212', 'Mitotic cells (Spleen)': '-0.272', 'Platelets': '-0.234', 'Erythrocytes': '-0.082', 'Hematopoietic stem cells': '-0.224', 'B-cells (Spleen)': '0.135', 'NK-cells (Spleen)': '0.315', 'Amygdala excitatory': '28.9', 'Cerebellar inhibitory': '19.6', 'Cge interneuron': '67.6', 'Deep-layer corticothalamic and 6b': '18.7', 'Deep-layer intratelencephalic': '12.8', 'Deep-layer near-projecting': '22.7', 'Eccentric medium spiny neuron': '74.5', 'Hippocampal ca1-3': '17.8', 'Hippocampal ca4': '7.7', 'Hippocampal dentate gyrus': '35.4', 'Lamp5-lhx6 and chandelier': '54.7', 'Lower rhombic lip': '60.0', 'Mammillary body': '85.4', 'Medium spiny neuron': '53.4', 'Mge interneuron': '57.0', 'Midbrain-derived inhibitory': '60.0', 'Miscellaneous': '21.4', 'Splatter': '74.4', 'Thalamic excitatory': '33.5', 'Upper rhombic lip': '46.2', 'Upper-layer intratelencephalic': '7.9', 'Astrocyte': '99.8', 'Bergmann glia': '78.4', 'Central nervous system macrophage': '2.9', 'Choroid plexus epithelial cell': '104.0', 'Committed oligodendrocyte precursor': '62.7', 'Ependymal cell': '99.1', 'Oligodendrocyte': '35.7', 'Oligodendrocyte precursor cell': '89.9', 'Endothelial cell': '6.5', 'Pericyte': '38.4', 'Vascular associated smooth muscle cell': '30.2', 'Fibroblast': '140.9', 'Leukocyte': '28.8', 'Basophil': '0.0', 'Eosinophil': '0.0', 'Neutrophil': '0.0', 'Classical monocyte': '0.0', 'Non-classical monocyte': '0.0', 'Intermediate monocyte': '0.0', 'T-reg': '0.0', 'GdT-cell': '0.0', 'MAIT T-cell': '0.3', 'Memory CD4 T-cell': '0.0', 'Naive CD4 T-cell': '2.8', 'Memory CD8 T-cell': '0.0', 'Naive CD8 T-cell': '4.7', 'Memory B-cell': '0.0', 'Naive B-cell': '1.2', 'Plasmacytoid DC': '0.1', 'Myeloid DC': '0.0', 'NK-cell': '10.3', 'Total PBMC': '0.2', 'Vd2 gdTCR': '0.0', 'Memory CD4 T-cell TFH': '3.9', 'Memory CD4 T-cell Th2': '2.4', 'Memory CD4 T-cell Th17': '2.7', 'Memory CD4 T-cell Th1\\/Th17': '1.2', 'Non-Vd2 gdTCR': '1.8', 'Memory CD4 T-cell Th1': '2.0', 'Terminal effector memory CD4 T-cell': '0.0', 'Central memory CD8 T-cell': '0.8', 'Effector memory CD8 T-cell': '0.2', 'Terminal effector memory CD8 T-cell': '0.5', 'Switched memory B-cell': '0.1', 'Plasmablast': '1.0', 'Non-switched memory B-cell': '0.1', 'Exhausted memory B-cell': '0.0', 'Progenitor cell': '0.0', 'Naive CD4 T-cell activated': '1.5', 'Naive CD8 T-cell activated': '2.7', 'Memory T-reg': '0.8', 'Naive T-reg': '2.1'}
null
{'Adipose Tissue': 7.022686877076413, 'Adrenal Gland': 13.696748062015503, 'Bladder': 7.46352380952381, 'Blood': 0.2918293573735199, 'Blood Vessel': 10.09955370786517, 'Brain': 10.793424564723692, 'Breast': 8.766941176470588, 'Cervix Uteri': 26.58, 'Colon': 14.039823106546857, 'Esophagus': 8.060666435986159, 'Fallopian Tube': 12.965, 'Heart': 3.5011507549361207, 'Kidney': 17.04907865168539, 'Liver': 6.804843362831859, 'Lung': 9.610017301038065, 'Muscle': 0.969966189290162, 'Nerve': 9.159205169628432, 'Ovary': 44.28771666666667, 'Pancreas': 3.865286585365854, 'Pituitary': 19.340180212014133, 'Prostate': 19.451412244897956, 'Salivary Gland': 7.046987654320988, 'Skin': 4.903636207849641, 'Small Intestine': 7.327304812834224, 'Spleen': 10.525842323651451, 'Stomach': 9.6901504178273, 'Testis': 19.613573407202217, 'Thyroid': 24.104353751914243, 'Uterus': 22.078401408450706, 'Vagina': 19.453685897435896}
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0.64, 0.56, 0.53, 0.56, 0.81, 0.54, 0.46, 0.55, 0.48, 0.54, 0.8, 0.76, 0.81]
null
Component of an E-cadherin/ catenin adhesion complex composed of at least E-cadherin/CDH1, beta-catenin/CTNNB1 or gamma-catenin/JUP, and potentially alpha-catenin/CTNNA1. Forms a ternary complex composed of ADAM10, CADH1 and EPHA4,
null
null
KLRG1, SPEF1, DLGAP5, AJAP1, RAPGEF2, RAB8B, PIP5K1C, PKP2, TRPV4, CTNNB1, CAV1, DDR1, TBC1D2, CTNNA1, JUP, CTNND1, PSEN1, LIMA1, CDH1, JUP, ADAM10, CADH1 , EPHA4,
null
null
null
null
Homodimer
null
79.91949
0.474025
66.506013
0.644305
245
P12830
Q9Y2M0
null
degron_data
CDH1
MGPWSRSLSALLLLLQVSSWLCQEPEPCHPGFDAESYTFTVPRRHLERGRVLGRVNFEDCTGRQRTAYFSLDTRFKVGTDGVITVKRPLRFHNPQIHFLVYAWDSTYRKFSTKVTLNTVGHHHRPPPHQASVSGIQAELLTFPNSSPGLRRQKRDWVIPPISCPENEKGPFPKNLVQIKSNKDKEGKVFYSITGQGADTPPVGVFIIERETGWLKVTEPLDRERIATYTLFSHAVSSNGNAVEDPMEILITVTDQNDNKPEFTQEVFKGSVMEGALPGTSVMEVTATDADDDVNTYNAAIAYTILSQDPELPDKNMFTINRNTGVISVVTTGLDRESFPTYTLVVQAADLQGEGLSTTATAVITVTDTNDNPPIFNPTTYKGQVPENEANVVITTLKVTDADAPNTPAWEAVYTILNDDGGQFVVTTNPVNNDGILKTAKGLDFEAKQQYILHVAVTNVVPFEVSLTTSTATVTVDVLDVNEAPIFVPPEKRVEVSEDFGVGQEITSYTAQEPDTFMEQKITYRIWRDTANWLEINPDTGAISTRAELDREDFEHVKNSTYTALIIATDNGSPVATGTGTLLLILSDVNDNAPIPEPRTIFFCERNPKPQVINIIDADLPPNTSPFTAELTHGASANWTIQYNDPTQESIILKPKMALEVGDYKINLKLMDNQNKDQVTTLEVSVCDCEGAAGVCRKAQPVEAGLQIPAILGILGGILALLILILLLLLFLRRRAVVKEPLLPPEDDTRDNVYYYDEEGGGEEDQDFDLSQLHRGLDARPEVTRNDVAPTLMSVPRYLPRPANPDEIGNFIDENLKAADTDPTAPPYDSLLVFDYEGSGSEAASLSSLNSSESDKDQDYDYLNEWGNRFKKLADMYGGGEDD
Homo sapiens
Cell junction, adherens junction, Cell membrane, Endosome, Golgi apparatus, trans-Golgi network, Cytoplasm, Cell junction, desmosome
Tissue enhanced (parathyroid)
{'Ciliated cells': '119.1', 'Basal respiratory cells': '71.1', 'Club cells': '97.3', 'Ionocytes': '81.0', 'Mucus glandular cells': '155.0', 'Serous glandular cells': '67.8', 'Gastric mucus-secreting cells': '133.2', 'Proximal enterocytes': '140.9', 'Paneth cells': '125.1', 'Distal enterocytes': '307.5', 'Intestinal goblet cells': '173.5', 'Exocrine glandular cells': '-0.605', 'Basal prostatic cells': '68.3', 'Prostatic glandular cells': '186.7', 'Breast glandular cells': '0.773', 'Breast myoepithelial cells': '0.700', 'Glandular and luminal cells': '313.0', 'Secretory cells': '82.3', 'Basal keratinocytes': '102.5', 'Suprabasal keratinocytes': '162.6', 'Basal squamous epithelial cells': '51.0', 'Squamous epithelial cells': '106.9', 'Alveolar cells type 1': '0.437', 'Alveolar cells type 2': '0.706', 'Salivary duct cells': '95.9', 'Ductal cells': '0.541', 'Hepatocytes': '0.600', 'Cholangiocytes': '129.7', 'Proximal tubular cells': '0.042', 'Distal tubular cells': '0.0', 'Collecting duct cells': '143.9', 'Mesothelial cells': '0.799', 'Sertoli cells': '0.252', 'Granulosa cells': '12.9', 'Enteroendocrine cells': '92.4', 'Pancreatic endocrine cells': '78.1', 'Leydig cells': '0.264', 'Excitatory neurons': '0.7', 'Inhibitory neurons': '1.3', 'Cone photoreceptor cells': '0.0', 'Rod photoreceptor cells': '0.0', 'Bipolar cells': '0.2', 'Horizontal cells': '0.6', 'Astrocytes': '0.6', 'Oligodendrocyte precursor cells': '0.5', 'Oligodendrocytes': '29.9', 'Microglial cells': '0.9', 'Muller glia cells': '0.1', 'Schwann cells': '0.131', 'Spermatogonia': '0.392', 'Spermatocytes': '0.193', 'Early spermatids': '-0.217', 'Late spermatids': '-0.290', 'Oocytes': '16.9', 'Cytotrophoblasts': '119.2', 'Syncytiotrophoblasts': '45.0', 'Extravillous trophoblasts': '24.9', 'Endothelial cells': '6.1', 'Lymphatic endothelial cells': '0.4', 'Cardiomyocytes': '0.135', 'Skeletal myocytes': '0.107', 'Smooth muscle cells': '5.8', 'Adipocytes': '2.1', 'Melanocytes': '0.335', 'Fibroblasts': '6.5', 'Peritubular cells': '0.210', 'Endometrial stromal cells': '27.7', 'Ovarian stromal cells': '0.7', 'Undifferentiated cells': '101.6', 'T-cells': '2.9', 'B-cells': '4.4', 'Plasma cells': '6.1', 'Nk-cells': '0.0', 'Granulocytes': '8.4', 'Monocytes': '0.0', 'Macrophages': '6.0', 'Hofbauer cells': '4.3', 'Kupffer cells': '1.0', 'Dendritic cells': '5.9', 'Langerhans cells': '0.304', 'Erythroid cells': '0.036', 'Adipocytes (Subcutaneous)': '-0.081', 'Adipocytes (Visceral)': '-0.209', 'Breast glandular cells (progenitors)': '0.538', 'Adipocytes (Breast)': '-0.689', 'Colon enterocytes': '0.790', 'Colon enteroendocrine cells': '0.112', 'Enteric glia cells': '-0.048', 'Mitotic cells (Colon)': '0.299', 'Mitotic cells (Heart)': '0.120', 'Podocytes': '-0.118', 'Ascending Loop of Henle cells': '0.475', 'Intercalated cells': '0.212', 'Cholangiocyte': '0.090', 'NK-cells (Liver)': '-0.005', 'Respiratory ciliated cells': '-0.012', 'Mitotic cells (Lung)': '0.071', 'NK-cells (Lung)': '-0.266', 'B-cells (Lung)': '-0.296', 'Alpha cells': '0.270', 'Beta cells': '0.152', 'Prostate glandular cells': '0.764', 'Prostate basal glandular cells': '0.540', 'Urothelial cells': '0.205', 'Keratinocyte (other)': '0.510', 'Keratinocyte (granular)': '0.055', 'Hair cortex cells': '0.080', 'Inner root sheath cells': '0.131', 'Outer root sheath cells': '0.175', 'Sebaceous gland cells': '0.156', 'Eccrine sweat gland cells': '-0.207', 'Adipocytes (Skin)': '-0.244', 'Mitotic cells (Skin)': '0.442', 'Parietal cells': '0.654', 'Chief cells': '0.649', 'Gastric mucous cells': '0.781', 'Gastric enteroendocrine cells': '0.590', 'Mitotic cells (Stomach)': '0.445', 'Parafollicular cells': '0.173', 'Thyroid glandular cells': '0.865', 'Mitotic cells (Thyroid)': '-0.081', 'Adrenal cortex cells': '0.051', 'Adrenal medulla cells': '0.087', 'Mitotic cells (Adrenal gland)': '0.072', 'Minor salivary glandular cells': '0.371', 'Minor salivary gland ductal cells': '-0.142', 'Minor salivary gland basal cells': '0.582', 'Mitotic cells (Minor salivary gland)': '0.567', 'Adipocytes (Minor salivary gland)': '0.050', 'Somatotropes': '0.121', 'Lactotropes': '0.322', 'Gonadotropes': '0.330', 'Corticotropes': '0.180', 'Thyrotropes': '0.496', 'Undifferentiated cells (Pituitary gland)': '-0.108', 'Mitotic cells (Spleen)': '-0.228', 'Platelets': '-0.050', 'Erythrocytes': '-0.158', 'Hematopoietic stem cells': '-0.211', 'B-cells (Spleen)': '0.266', 'NK-cells (Spleen)': '0.309', 'Amygdala excitatory': '1.0', 'Cerebellar inhibitory': '0.9', 'Cge interneuron': '0.7', 'Deep-layer corticothalamic and 6b': '1.5', 'Deep-layer intratelencephalic': '0.7', 'Deep-layer near-projecting': '0.7', 'Eccentric medium spiny neuron': '0.6', 'Hippocampal ca1-3': '1.9', 'Hippocampal ca4': '1.2', 'Hippocampal dentate gyrus': '1.1', 'Lamp5-lhx6 and chandelier': '0.5', 'Lower rhombic lip': '0.8', 'Mammillary body': '0.6', 'Medium spiny neuron': '0.7', 'Mge interneuron': '1.7', 'Midbrain-derived inhibitory': '0.7', 'Miscellaneous': '0.9', 'Splatter': '3.8', 'Thalamic excitatory': '0.5', 'Upper rhombic lip': '0.8', 'Upper-layer intratelencephalic': '0.6', 'Astrocyte': '4.4', 'Bergmann glia': '0.2', 'Central nervous system macrophage': '0.6', 'Choroid plexus epithelial cell': '52.1', 'Committed oligodendrocyte precursor': '41.5', 'Ependymal cell': '4.8', 'Oligodendrocyte': '53.1', 'Oligodendrocyte precursor cell': '2.4', 'Endothelial cell': '0.7', 'Pericyte': '0.3', 'Vascular associated smooth muscle cell': '0.0', 'Fibroblast': '17.4', 'Leukocyte': '1.1', 'Basophil': '0.0', 'Eosinophil': '0.0', 'Neutrophil': '0.0', 'Classical monocyte': '0.0', 'Non-classical monocyte': '0.0', 'Intermediate monocyte': '0.0', 'T-reg': '2.3', 'GdT-cell': '0.0', 'MAIT T-cell': '0.0', 'Memory CD4 T-cell': '0.0', 'Naive CD4 T-cell': '0.1', 'Memory CD8 T-cell': '0.2', 'Naive CD8 T-cell': '0.3', 'Memory B-cell': '0.0', 'Naive B-cell': '0.1', 'Plasmacytoid DC': '46.6', 'Myeloid DC': '8.5', 'NK-cell': '0.1', 'Total PBMC': '0.7', 'Vd2 gdTCR': '0.0', 'Memory CD4 T-cell Th1\\/Th17': '0.1', 'Memory CD4 T-cell Th17': '0.2', 'Memory CD4 T-cell Th2': '2.9', 'Non-Vd2 gdTCR': '0.1', 'Memory CD4 T-cell Th1': '0.3', 'Memory CD4 T-cell TFH': '0.5', 'Terminal effector memory CD4 T-cell': '0.0', 'Central memory CD8 T-cell': '4.8', 'Effector memory CD8 T-cell': '0.0', 'Terminal effector memory CD8 T-cell': '0.6', 'Non-switched memory B-cell': '0.0', 'Plasmablast': '3.3', 'Switched memory B-cell': '0.0', 'Exhausted memory B-cell': '0.7', 'Progenitor cell': '2.3', 'Memory T-reg': '1.3', 'Naive CD4 T-cell activated': '0.3', 'Naive CD8 T-cell activated': '0.6', 'Naive T-reg': '0.1'}
1O6S, 2O72, 2OMT, 2OMU, 2OMV, 2OMX, 2OMY, 2OMZ, 3FF7, 3FF8, 3L6X, 3L6Y, 4ZT1, 4ZTE, 6CXY, 6OLE, 6OLF, 6OLG, 6VEL, 7STZ, 8H62
{'Adipose Tissue': 1.2125261088039867, 'Adrenal Gland': 0.1914223992248062, 'Bladder': 39.2033519047619, 'Blood': 1.340954264800861, 'Blood Vessel': 0.3121561692883895, 'Brain': 0.8550442199091597, 'Breast': 38.54918344226579, 'Cervix Uteri': 23.539115789473684, 'Colon': 43.41292142490372, 'Esophagus': 53.97513367404844, 'Fallopian Tube': 14.900277777777776, 'Heart': 0.119140469221835, 'Kidney': 25.040449438202245, 'Liver': 26.60802654867257, 'Lung': 35.447986366782004, 'Muscle': 0.1378936151930261, 'Nerve': 17.518468982229404, 'Ovary': 3.6515122222222223, 'Pancreas': 56.89676829268293, 'Pituitary': 24.68741660777385, 'Prostate': 61.279967346938776, 'Salivary Gland': 92.01685185185184, 'Skin': 79.77571720232172, 'Small Intestine': 71.7519320855615, 'Spleen': 10.061029045643156, 'Stomach': 58.07813805013927, 'Testis': 0.8144204986149585, 'Thyroid': 135.176797856049, 'Uterus': 1.442593943661972, 'Vagina': 86.52345512820513}
FAN1
MMSEGKPPDKKRPRRSLSISKNKKKASNSIISCFNNAPPAKLACPVCSKMVPRYDLNRHLDEMCANNDFVQVDPGQVGLINSNVSMVDLTSVTLEDVTPKKSPPPKTNLTPGQSDSAKREVKQKISPYFKSNDVVCKNQDELRNRSVKVICLGSLASKLSRKYVKAKKSIDKDEEFAGSSPQSSKSTVVKSLIDNSSEIEDEDQILENSSQKENVFKCDSLKEECIPEHMVRGSKIMEAESQKATRECEKSALTPGFSDNAIMLFSPDFTLRNTLKSTSEDSLVKQECIKEVVEKREACHCEEVKMTVASEAKIQLSDSEAKSHSSADDASAWSNIQEAPLQDDSCLNNDIPHSIPLEQGSSCNGPGQTTGHPYYLRSFLVVLKTVLENEDDMLLFDEQEKGIVTKFYQLSATGQKLYVRLFQRKLSWIKMTKLEYEEIALDLTPVIEELTNAGFLQTESELQELSEVLELLSAPELKSLAKTFHLVNPNGQKQQLVDAFLKLAKQRSVCTWGKNKPGIGAVILKRAKALAGQSVRICKGPRAVFSRILLLFSLTDSMEDEDAACGGQGQLSTVLLVNLGRMEFPSYTINRKTHIFQDRDDLIRYAAATHMLSDISSAMANGNWEEAKELAQCAKRDWNRLKNHPSLRCHEDLPLFLRCFTVGWIYTRILSRFVEILQRLHMYEEAVRELESLLSQRIYCPDSRGRWWDRLALNLHQHLKRLEPTIKCITEGLADPEVRTGHRLSLYQRAVRLRESPSCKKFKHLFQQLPEMAVQDVKHVTITGRLCPQRGMCKSVFVMEAGEAADPTTVLCSVEELALAHYRRSGFDQGIHGEGSTFSTLYGLLLWDIIFMDGIPDVFRNACQAFPLDLCTDSFFTSRRPALEARLQLIHDAPEESLRAWVAATWHEQEGRVASLVSWDRFTSLQQAQDLVSCLGGPVLSGVCRHLAADFRHCRGGLPDLVVWNSQSRHFKLVEVKGPNDRLSHKQMIWLAELQKLGAEVEVCHVVAVGAKSQSLS
Homo sapiens
Nucleus
Low tissue specificity
{'Ciliated cells': '10.7', 'Basal respiratory cells': '4.6', 'Club cells': '12.5', 'Ionocytes': '9.9', 'Mucus glandular cells': '16.3', 'Serous glandular cells': '13.8', 'Gastric mucus-secreting cells': '10.6', 'Proximal enterocytes': '4.5', 'Paneth cells': '8.0', 'Distal enterocytes': '7.2', 'Intestinal goblet cells': '13.8', 'Exocrine glandular cells': '-0.366', 'Basal prostatic cells': '12.1', 'Prostatic glandular cells': '33.1', 'Breast glandular cells': '0.517', 'Breast myoepithelial cells': '0.498', 'Glandular and luminal cells': '10.6', 'Secretory cells': '9.1', 'Basal keratinocytes': '7.9', 'Suprabasal keratinocytes': '5.6', 'Basal squamous epithelial cells': '10.4', 'Squamous epithelial cells': '6.7', 'Alveolar cells type 1': '0.036', 'Alveolar cells type 2': '-0.002', 'Salivary duct cells': '15.2', 'Ductal cells': '0.447', 'Hepatocytes': '0.528', 'Cholangiocytes': '1.9', 'Proximal tubular cells': '0.184', 'Distal tubular cells': '3.1', 'Collecting duct cells': '13.6', 'Mesothelial cells': '0.318', 'Sertoli cells': '-0.344', 'Granulosa cells': '15.1', 'Enteroendocrine cells': '13.1', 'Pancreatic endocrine cells': '1.7', 'Leydig cells': '-0.333', 'Excitatory neurons': '22.9', 'Inhibitory neurons': '24.4', 'Cone photoreceptor cells': '32.3', 'Rod photoreceptor cells': '34.3', 'Bipolar cells': '23.7', 'Horizontal cells': '30.2', 'Astrocytes': '20.1', 'Oligodendrocyte precursor cells': '12.7', 'Oligodendrocytes': '41.2', 'Microglial cells': '14.3', 'Muller glia cells': '13.6', 'Schwann cells': '0.087', 'Spermatogonia': '0.000', 'Spermatocytes': '0.364', 'Early spermatids': '0.528', 'Late spermatids': '0.335', 'Oocytes': '1.5', 'Cytotrophoblasts': '8.8', 'Syncytiotrophoblasts': '6.5', 'Extravillous trophoblasts': '2.6', 'Endothelial cells': '11.9', 'Lymphatic endothelial cells': '9.8', 'Cardiomyocytes': '0.690', 'Skeletal myocytes': '-0.268', 'Smooth muscle cells': '9.1', 'Adipocytes': '10.2', 'Melanocytes': '0.085', 'Fibroblasts': '10.3', 'Peritubular cells': '-0.083', 'Endometrial stromal cells': '13.8', 'Ovarian stromal cells': '13.8', 'Undifferentiated cells': '10.6', 'T-cells': '7.4', 'B-cells': '6.4', 'Plasma cells': '8.9', 'Nk-cells': '6.6', 'Granulocytes': '8.9', 'Monocytes': '3.3', 'Macrophages': '5.6', 'Hofbauer cells': '4.3', 'Kupffer cells': '6.0', 'Dendritic cells': '2.4', 'Langerhans cells': '0.215', 'Erythroid cells': '-0.132', 'Adipocytes (Subcutaneous)': '0.075', 'Adipocytes (Visceral)': '-0.089', 'Breast glandular cells (progenitors)': '0.478', 'Adipocytes (Breast)': '-0.423', 'Colon enterocytes': '-0.031', 'Colon enteroendocrine cells': '0.113', 'Enteric glia cells': '-0.279', 'Mitotic cells (Colon)': '-0.077', 'Mitotic cells (Heart)': '0.437', 'Podocytes': '-0.131', 'Ascending Loop of Henle cells': '0.592', 'Intercalated cells': '0.085', 'Cholangiocyte': '0.165', 'NK-cells (Liver)': '-0.234', 'Respiratory ciliated cells': '0.077', 'Mitotic cells (Lung)': '0.113', 'NK-cells (Lung)': '-0.025', 'B-cells (Lung)': '-0.100', 'Alpha cells': '0.379', 'Beta cells': '0.313', 'Prostate glandular cells': '0.279', 'Prostate basal glandular cells': '0.434', 'Urothelial cells': '0.175', 'Keratinocyte (other)': '0.203', 'Keratinocyte (granular)': '-0.079', 'Hair cortex cells': '-0.083', 'Inner root sheath cells': '-0.013', 'Outer root sheath cells': '0.094', 'Sebaceous gland cells': '0.089', 'Eccrine sweat gland cells': '0.005', 'Adipocytes (Skin)': '-0.091', 'Mitotic cells (Skin)': '0.361', 'Parietal cells': '-0.380', 'Chief cells': '-0.359', 'Gastric mucous cells': '-0.292', 'Gastric enteroendocrine cells': '-0.283', 'Mitotic cells (Stomach)': '0.068', 'Parafollicular cells': '0.089', 'Thyroid glandular cells': '0.371', 'Mitotic cells (Thyroid)': '-0.050', 'Adrenal cortex cells': '0.586', 'Adrenal medulla cells': '0.002', 'Mitotic cells (Adrenal gland)': '0.462', 'Minor salivary glandular cells': '0.296', 'Minor salivary gland ductal cells': '0.453', 'Minor salivary gland basal cells': '-0.150', 'Mitotic cells (Minor salivary gland)': '-0.225', 'Adipocytes (Minor salivary gland)': '-0.009', 'Somatotropes': '0.283', 'Lactotropes': '0.186', 'Gonadotropes': '0.102', 'Corticotropes': '-0.064', 'Thyrotropes': '0.135', 'Undifferentiated cells (Pituitary gland)': '0.027', 'Mitotic cells (Spleen)': '0.016', 'Platelets': '-0.181', 'Erythrocytes': '-0.065', 'Hematopoietic stem cells': '-0.255', 'B-cells (Spleen)': '0.241', 'NK-cells (Spleen)': '0.231', 'Amygdala excitatory': '37.0', 'Cerebellar inhibitory': '45.2', 'Cge interneuron': '50.5', 'Deep-layer corticothalamic and 6b': '36.3', 'Deep-layer intratelencephalic': '41.3', 'Deep-layer near-projecting': '32.6', 'Eccentric medium spiny neuron': '33.1', 'Hippocampal ca1-3': '41.1', 'Hippocampal ca4': '38.3', 'Hippocampal dentate gyrus': '41.4', 'Lamp5-lhx6 and chandelier': '38.3', 'Lower rhombic lip': '82.2', 'Mammillary body': '52.3', 'Medium spiny neuron': '32.8', 'Mge interneuron': '37.8', 'Midbrain-derived inhibitory': '38.0', 'Miscellaneous': '38.6', 'Splatter': '47.7', 'Thalamic excitatory': '48.7', 'Upper rhombic lip': '48.8', 'Upper-layer intratelencephalic': '37.4', 'Astrocyte': '49.9', 'Bergmann glia': '37.9', 'Central nervous system macrophage': '44.1', 'Choroid plexus epithelial cell': '51.2', 'Committed oligodendrocyte precursor': '51.4', 'Ependymal cell': '36.5', 'Oligodendrocyte': '83.9', 'Oligodendrocyte precursor cell': '52.8', 'Endothelial cell': '30.5', 'Pericyte': '23.8', 'Vascular associated smooth muscle cell': '16.9', 'Fibroblast': '39.0', 'Leukocyte': '25.3', 'Basophil': '0.7', 'Eosinophil': '0.0', 'Neutrophil': '0.2', 'Classical monocyte': '6.7', 'Non-classical monocyte': '10.1', 'Intermediate monocyte': '0.2', 'T-reg': '0.7', 'GdT-cell': '1.4', 'MAIT T-cell': '0.7', 'Memory CD4 T-cell': '1.2', 'Naive CD4 T-cell': '45.3', 'Memory CD8 T-cell': '0.7', 'Naive CD8 T-cell': '36.8', 'Memory B-cell': '1.2', 'Naive B-cell': '23.3', 'Plasmacytoid DC': '1.7', 'Myeloid DC': '1.0', 'NK-cell': '21.0', 'Total PBMC': '1.1', 'Vd2 gdTCR': '1.2', 'Memory CD4 T-cell TFH': '33.2', 'Memory CD4 T-cell Th2': '37.0', 'Memory CD4 T-cell Th17': '33.0', 'Memory CD4 T-cell Th1\\/Th17': '33.1', 'Non-Vd2 gdTCR': '0.8', 'Memory CD4 T-cell Th1': '32.2', 'Terminal effector memory CD4 T-cell': '1.6', 'Central memory CD8 T-cell': '1.1', 'Effector memory CD8 T-cell': '0.8', 'Terminal effector memory CD8 T-cell': '0.5', 'Switched memory B-cell': '0.5', 'Plasmablast': '1.4', 'Non-switched memory B-cell': '2.1', 'Exhausted memory B-cell': '0.4', 'Progenitor cell': '3.2', 'Memory T-reg': '23.1', 'Naive CD4 T-cell activated': '19.6', 'Naive CD8 T-cell activated': '19.6', 'Naive T-reg': '37.1'}
4REA, 4REB, 4REC, 4RI8, 4RI9, 4RIA, 4RIB, 4RIC, 4RID, 4RY3
{'Adipose Tissue': 8.615357142857142, 'Adrenal Gland': 8.992126744186047, 'Bladder': 12.963190476190476, 'Blood': 3.785463928955867, 'Blood Vessel': 9.719731835205993, 'Brain': 9.417120439061318, 'Breast': 10.191457516339868, 'Cervix Uteri': 15.852631578947369, 'Colon': 11.586713735558408, 'Esophagus': 10.16189259515571, 'Fallopian Tube': 14.861333333333334, 'Heart': 5.4459585365853656, 'Kidney': 6.5063483146067425, 'Liver': 4.782192477876106, 'Lung': 8.906005190311419, 'Muscle': 12.210916562889166, 'Nerve': 15.830987075928917, 'Ovary': 17.871316666666665, 'Pancreas': 7.008591463414635, 'Pituitary': 13.215749116607771, 'Prostate': 14.036542857142855, 'Salivary Gland': 12.212685185185183, 'Skin': 13.966011608623548, 'Small Intestine': 9.54048128342246, 'Spleen': 7.814053941908713, 'Stomach': 9.141462395543176, 'Testis': 18.6223324099723, 'Thyroid': 16.05051301684533, 'Uterus': 17.117225352112676, 'Vagina': 14.454153846153844}
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32.62, 29.27, 33.59, 31.38, 29.31]
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null
Component of an E-cadherin/ catenin adhesion complex composed of at least E-cadherin/CDH1, beta-catenin/CTNNB1 or gamma-catenin/JUP, and potentially alpha-catenin/CTNNA1. Forms a ternary complex composed of ADAM10, CADH1 and EPHA4,
null
null
KLRG1, SPEF1, DLGAP5, AJAP1, RAPGEF2, RAB8B, PIP5K1C, PKP2, TRPV4, CTNNB1, CAV1, DDR1, TBC1D2, CTNNA1, JUP, CTNND1, PSEN1, LIMA1, CDH1, JUP, ADAM10, CADH1 , EPHA4,
null
null
null
null
Homodimer
null
79.91949
0.474025
69.866303
0.504985
501
P14373
O00750
22128329
UbiNet, UbiBrowser
TRIM27
MASGSVAECLQQETTCPVCLQYFAEPMMLDCGHNICCACLARCWGTAETNVSCPQCRETFPQRHMRPNRHLANVTQLVKQLRTERPSGPGGEMGVCEKHREPLKLYCEEDQMPICVVCDRSREHRGHSVLPLEEAVEGFKEQIQNQLDHLKRVKDLKKRRRAQGEQARAELLSLTQMEREKIVWEFEQLYHSLKEHEYRLLARLEELDLAIYNSINGAITQFSCNISHLSSLIAQLEEKQQQPTRELLQDIGDTLSRAERIRIPEPWITPPDLQEKIHIFAQKCLFLTESLKQFTEKMQSDMEKIQELREAQLYSVDVTLDPDTAYPSLILSDNLRQVRYSYLQQDLPDNPERFNLFPCVLGSPCFIAGRHYWEVEVGDKAKWTIGVCEDSVCRKGGVTSAPQNGFWAVSLWYGKEYWALTSPMTALPLRTPLQRVGIFLDYDAGEVSFYNVTERCHTFTFSHATFCGPVRPYFSLSYSGGKSAAPLIICPMSGIDGFSGHVGNHGHSMETSP
Homo sapiens
Nucleus, Cytoplasm, Nucleus, PML body, Early endosome, Mitochondrion
Low tissue specificity
{'Ciliated cells': '25.1', 'Basal respiratory cells': '27.3', 'Club cells': '24.7', 'Ionocytes': '23.2', 'Mucus glandular cells': '21.7', 'Serous glandular cells': '33.5', 'Gastric mucus-secreting cells': '23.6', 'Proximal enterocytes': '20.1', 'Paneth cells': '20.0', 'Distal enterocytes': '15.1', 'Intestinal goblet cells': '37.0', 'Exocrine glandular cells': '-0.693', 'Basal prostatic cells': '43.6', 'Prostatic glandular cells': '43.5', 'Breast glandular cells': '0.696', 'Breast myoepithelial cells': '0.544', 'Glandular and luminal cells': '29.8', 'Secretory cells': '37.3', 'Basal keratinocytes': '26.5', 'Suprabasal keratinocytes': '15.7', 'Basal squamous epithelial cells': '34.1', 'Squamous epithelial cells': '21.9', 'Alveolar cells type 1': '-0.038', 'Alveolar cells type 2': '-0.408', 'Salivary duct cells': '18.1', 'Ductal cells': '0.480', 'Hepatocytes': '0.177', 'Cholangiocytes': '22.9', 'Proximal tubular cells': '0.232', 'Distal tubular cells': '18.4', 'Collecting duct cells': '27.2', 'Mesothelial cells': '0.392', 'Sertoli cells': '0.703', 'Granulosa cells': '19.2', 'Enteroendocrine cells': '31.0', 'Pancreatic endocrine cells': '18.7', 'Leydig cells': '0.636', 'Excitatory neurons': '13.0', 'Inhibitory neurons': '12.8', 'Cone photoreceptor cells': '13.6', 'Rod photoreceptor cells': '11.3', 'Bipolar cells': '10.1', 'Horizontal cells': '7.6', 'Astrocytes': '11.1', 'Oligodendrocyte precursor cells': '17.9', 'Oligodendrocytes': '18.4', 'Microglial cells': '16.1', 'Muller glia cells': '12.1', 'Schwann cells': '0.026', 'Spermatogonia': '0.420', 'Spermatocytes': '-0.042', 'Early spermatids': '-0.589', 'Late spermatids': '-0.706', 'Oocytes': '13.2', 'Cytotrophoblasts': '48.8', 'Syncytiotrophoblasts': '50.5', 'Extravillous trophoblasts': '58.8', 'Endothelial cells': '27.6', 'Lymphatic endothelial cells': '18.3', 'Cardiomyocytes': '0.444', 'Skeletal myocytes': '-0.371', 'Smooth muscle cells': '19.7', 'Adipocytes': '20.7', 'Melanocytes': '-0.177', 'Fibroblasts': '22.4', 'Peritubular cells': '0.559', 'Endometrial stromal cells': '27.3', 'Ovarian stromal cells': '24.5', 'Undifferentiated cells': '29.3', 'T-cells': '28.5', 'B-cells': '33.6', 'Plasma cells': '50.4', 'Nk-cells': '25.7', 'Granulocytes': '27.4', 'Monocytes': '32.5', 'Macrophages': '29.6', 'Hofbauer cells': '38.9', 'Kupffer cells': '31.1', 'Dendritic cells': '32.8', 'Langerhans cells': '0.075', 'Erythroid cells': '-0.057', 'Adipocytes (Subcutaneous)': '-0.199', 'Adipocytes (Visceral)': '-0.372', 'Breast glandular cells (progenitors)': '0.493', 'Adipocytes (Breast)': '-0.659', 'Colon enterocytes': '-0.039', 'Colon enteroendocrine cells': '0.155', 'Enteric glia cells': '0.411', 'Mitotic cells (Colon)': '0.069', 'Mitotic cells (Heart)': '0.481', 'Podocytes': '-0.080', 'Ascending Loop of Henle cells': '0.332', 'Intercalated cells': '-0.067', 'Cholangiocyte': '0.283', 'NK-cells (Liver)': '-0.293', 'Respiratory ciliated cells': '0.036', 'Mitotic cells (Lung)': '-0.109', 'NK-cells (Lung)': '0.295', 'B-cells (Lung)': '0.112', 'Alpha cells': '0.335', 'Beta cells': '0.170', 'Prostate glandular cells': '0.251', 'Prostate basal glandular cells': '0.383', 'Urothelial cells': '0.310', 'Keratinocyte (other)': '-0.109', 'Keratinocyte (granular)': '-0.354', 'Hair cortex cells': '0.029', 'Inner root sheath cells': '0.037', 'Outer root sheath cells': '0.284', 'Sebaceous gland cells': '0.136', 'Eccrine sweat gland cells': '0.208', 'Adipocytes (Skin)': '0.020', 'Mitotic cells (Skin)': '0.110', 'Parietal cells': '-0.236', 'Chief cells': '-0.025', 'Gastric mucous cells': '0.098', 'Gastric enteroendocrine cells': '0.091', 'Mitotic cells (Stomach)': '0.263', 'Parafollicular cells': '0.070', 'Thyroid glandular cells': '0.072', 'Mitotic cells (Thyroid)': '0.055', 'Adrenal cortex cells': '0.312', 'Adrenal medulla cells': '-0.104', 'Mitotic cells (Adrenal gland)': '-0.086', 'Minor salivary glandular cells': '0.517', 'Minor salivary gland ductal cells': '0.287', 'Minor salivary gland basal cells': '-0.017', 'Mitotic cells (Minor salivary gland)': '0.010', 'Adipocytes (Minor salivary gland)': '0.057', 'Somatotropes': '0.482', 'Lactotropes': '0.227', 'Gonadotropes': '0.066', 'Corticotropes': '0.019', 'Thyrotropes': '0.026', 'Undifferentiated cells (Pituitary gland)': '-0.250', 'Mitotic cells (Spleen)': '-0.238', 'Platelets': '-0.171', 'Erythrocytes': '-0.096', 'Hematopoietic stem cells': '-0.313', 'B-cells (Spleen)': '0.377', 'NK-cells (Spleen)': '0.278', 'Amygdala excitatory': '29.4', 'Cerebellar inhibitory': '15.3', 'Cge interneuron': '27.6', 'Deep-layer corticothalamic and 6b': '29.3', 'Deep-layer intratelencephalic': '31.8', 'Deep-layer near-projecting': '34.8', 'Eccentric medium spiny neuron': '27.3', 'Hippocampal ca1-3': '26.5', 'Hippocampal ca4': '28.4', 'Hippocampal dentate gyrus': '29.8', 'Lamp5-lhx6 and chandelier': '22.8', 'Lower rhombic lip': '32.2', 'Mammillary body': '18.8', 'Medium spiny neuron': '22.8', 'Mge interneuron': '26.6', 'Midbrain-derived inhibitory': '28.4', 'Miscellaneous': '30.0', 'Splatter': '27.8', 'Thalamic excitatory': '23.9', 'Upper rhombic lip': '24.1', 'Upper-layer intratelencephalic': '28.8', 'Astrocyte': '26.3', 'Bergmann glia': '25.2', 'Central nervous system macrophage': '78.3', 'Choroid plexus epithelial cell': '42.9', 'Committed oligodendrocyte precursor': '33.8', 'Ependymal cell': '20.3', 'Oligodendrocyte': '36.0', 'Oligodendrocyte precursor cell': '32.2', 'Endothelial cell': '58.5', 'Pericyte': '33.4', 'Vascular associated smooth muscle cell': '31.7', 'Fibroblast': '43.5', 'Leukocyte': '58.3', 'Basophil': '20.3', 'Eosinophil': '2.5', 'Neutrophil': '51.3', 'Classical monocyte': '17.4', 'Non-classical monocyte': '33.2', 'Intermediate monocyte': '36.3', 'T-reg': '19.6', 'GdT-cell': '7.2', 'MAIT T-cell': '29.7', 'Memory CD4 T-cell': '10.6', 'Naive CD4 T-cell': '29.7', 'Memory CD8 T-cell': '5.6', 'Naive CD8 T-cell': '28.3', 'Memory B-cell': '7.1', 'Naive B-cell': '18.7', 'Plasmacytoid DC': '27.3', 'Myeloid DC': '30.5', 'NK-cell': '26.2', 'Total PBMC': '23.0', 'Vd2 gdTCR': '19.2', 'Memory CD4 T-cell Th1\\/Th17': '22.6', 'Memory CD4 T-cell Th17': '23.3', 'Memory CD4 T-cell Th2': '23.3', 'Non-Vd2 gdTCR': '18.3', 'Memory CD4 T-cell Th1': '23.8', 'Memory CD4 T-cell TFH': '24.9', 'Terminal effector memory CD4 T-cell': '26.8', 'Central memory CD8 T-cell': '23.4', 'Effector memory CD8 T-cell': '21.7', 'Terminal effector memory CD8 T-cell': '14.3', 'Non-switched memory B-cell': '22.5', 'Plasmablast': '44.1', 'Switched memory B-cell': '25.7', 'Exhausted memory B-cell': '13.9', 'Progenitor cell': '20.6', 'Memory T-reg': '26.0', 'Naive CD4 T-cell activated': '55.5', 'Naive CD8 T-cell activated': '61.3', 'Naive T-reg': '32.5'}
null
{'Adipose Tissue': 30.51002491694352, 'Adrenal Gland': 28.42209302325581, 'Bladder': 42.15761904761904, 'Blood': 47.71387405812702, 'Blood Vessel': 35.17883895131086, 'Brain': 17.082769114307343, 'Breast': 35.04257080610022, 'Cervix Uteri': 56.090526315789475, 'Colon': 26.715078305519896, 'Esophagus': 25.588709342560552, 'Fallopian Tube': 54.83888888888889, 'Heart': 12.228174216027876, 'Kidney': 20.893404494382025, 'Liver': 28.784889380530977, 'Lung': 43.63569204152249, 'Muscle': 13.141891656288918, 'Nerve': 43.2170436187399, 'Ovary': 50.49094444444445, 'Pancreas': 26.43318292682927, 'Pituitary': 49.52038869257951, 'Prostate': 47.70363265306122, 'Salivary Gland': 32.1683950617284, 'Skin': 30.310514648977335, 'Small Intestine': 34.5279679144385, 'Spleen': 56.557759336099586, 'Stomach': 26.06833704735376, 'Testis': 26.19157894736842, 'Thyroid': 45.41816232771823, 'Uterus': 52.2319014084507, 'Vagina': 36.81769230769231}
PIK3C2B
MSSTQGNGEHWKSLESVGISRKELAMAEALQMEYDALSRLRHDKEENRAKQNADPSLISWDEPGVDFYSKPAGRRTDLKLLRGLSGSDPTLNYNSLSPQEGPPNHSTSQGPQPGSDPWPKGSLSGDYLYIFDGSDGGVSSSPGPGDIEGSCKKLSPPPLPPRASIWDTPPLPPRKGSPSSSKISQPSDINTFSLVEQLPGKLLEHRILEEEEVLGGGGQGRLLGSVDYDGINDAITRLNLKSTYDAEMLRDATRGWKEGRGPLDFSKDTSGKPVARSKTMPPQVPPRTYASRYGNRKNATPGKNRRISAAPVGSRPHTVANGHELFEVSEERDEEVAAFCHMLDILRSGSDIQDYFLTGYVWSAVTPSPEHLGDEVNLKVTVLCDRLQEALTFTCNCSSTVDLLIYQTLCYTHDDLRNVDVGDFVLKPCGLEEFLQNKHALGSHEYIQYCRKFDIDIRLQLMEQKVVRSDLARTVNDDQSPSTLNYLVHLQERPVKQTISRQALSLLFDTYHNEVDAFLLADGDFPLKADRVVQSVKAICNALAAVETPEITSALNQLPPCPSRMQPKIQKDPSVLAVRENREKVVEALTAAILDLVELYCNTFNADFQTAVPGSRKHDLVQEACHFARSLAFTVYATHRIPIIWATSYEDFYLSCSLSHGGKELCSPLQTRRAHFSKYLFHLIVWDQQICFPVQVNRLPRETLLCATLYALPIPPPGSSSEANKQRRVPEALGWVTTPLFNFRQVLTCGRKLLGLWPATQENPSARWSAPNFHQPDSVILQIDFPTSAFDIKFTSPPGDKFSPRYEFGSLREEDQRKLKDIMQKESLYWLTDADKKRLWEKRYYCHSEVSSLPLVLASAPSWEWACLPDIYVLLKQWTHMNHQDALGLLHATFPDQEVRRMAVQWIGSLSDAELLDYLPQLVQALKYECYLDSPLVRFLLKRAVSDLRVTHYFFWLLKDGLKDSQFSIRYQYLLAALLCCCGKGLREEFNRQCWLVNALAKLAQQVREAAPSARQGILRTGLEEVKQFFALNGSCRLPLSPSLLVKGIVPRDCSYFNSNAVPLKLSFQNVDPLGENIRVIFKCGDDLRQDMLTLQMIRIMSKIWVQEGLDMRMVIFRCFSTGRGRGMVEMIPNAETLRKIQVEHGVTGSFKDRPLADWLQKHNPGEDEYEKAVENFIYSCAGCCVATYVLGICDRHNDNIMLKTTGHMFHIDFGRFLGHAQMFGNIKRDRAPFVFTSDMAYVINGGDKPSSRFHDFVDLCCQAYNLIRKHTHLFLNLLGLMLSCGIPELSDLEDLKYVYDALRPQDTEANATTYFTRLIESSLGSVATKLNFFIHNLAQMKFTGSDDRLTLSFASRTHTLKSSGRISDVFLCRHEKIFHPNKGYIYVVKVMRENTHEATYIQRTFEEFQELHNKLRLLFPSSHLPSFPSRFVIGRSRGEAVAERRREELNGYIWHLIHAPPEVAECDLVYTFFHPLPRDEKAMGTSPAPKSSDGTWARPVGKVGGEVKLSISYKNNKLFIMVMHIRGLQLLQDGNDPDPYVKIYLLPDPQKTTKRKTKVARKTCNPTYNEMLVYDGIPKGDLQQRELQLSVLSEQGFWENVLLGEVNIRLRELDLAQEKTGWFALGSRSHGTL
Homo sapiens
Microsome, Cell membrane, Cytoplasm, cytosol, Nucleus, Endoplasmic reticulum
Low tissue specificity
{'Ciliated cells': '5.6', 'Basal respiratory cells': '7.8', 'Club cells': '11.9', 'Ionocytes': '10.7', 'Mucus glandular cells': '5.2', 'Serous glandular cells': '7.4', 'Gastric mucus-secreting cells': '24.2', 'Proximal enterocytes': '13.9', 'Paneth cells': '11.0', 'Distal enterocytes': '29.4', 'Intestinal goblet cells': '27.3', 'Exocrine glandular cells': '-0.374', 'Basal prostatic cells': '5.0', 'Prostatic glandular cells': '5.8', 'Breast glandular cells': '0.120', 'Breast myoepithelial cells': '0.199', 'Glandular and luminal cells': '2.3', 'Secretory cells': '1.6', 'Basal keratinocytes': '6.4', 'Suprabasal keratinocytes': '12.8', 'Basal squamous epithelial cells': '2.2', 'Squamous epithelial cells': '8.9', 'Alveolar cells type 1': '0.141', 'Alveolar cells type 2': '-0.347', 'Salivary duct cells': '3.4', 'Ductal cells': '0.439', 'Hepatocytes': '0.393', 'Cholangiocytes': '7.6', 'Proximal tubular cells': '-0.007', 'Distal tubular cells': '0.0', 'Collecting duct cells': '3.9', 'Mesothelial cells': '0.089', 'Sertoli cells': '0.338', 'Granulosa cells': '1.4', 'Enteroendocrine cells': '12.2', 'Pancreatic endocrine cells': '0.0', 'Leydig cells': '0.502', 'Excitatory neurons': '13.8', 'Inhibitory neurons': '21.8', 'Cone photoreceptor cells': '0.0', 'Rod photoreceptor cells': '0.7', 'Bipolar cells': '16.6', 'Horizontal cells': '15.1', 'Astrocytes': '15.2', 'Oligodendrocyte precursor cells': '22.2', 'Oligodendrocytes': '103.8', 'Microglial cells': '25.9', 'Muller glia cells': '2.8', 'Schwann cells': '0.267', 'Spermatogonia': '0.470', 'Spermatocytes': '-0.012', 'Early spermatids': '-0.469', 'Late spermatids': '-0.495', 'Oocytes': '5.9', 'Cytotrophoblasts': '4.3', 'Syncytiotrophoblasts': '2.5', 'Extravillous trophoblasts': '4.7', 'Endothelial cells': '24.5', 'Lymphatic endothelial cells': '10.0', 'Cardiomyocytes': '0.332', 'Skeletal myocytes': '0.594', 'Smooth muscle cells': '4.6', 'Adipocytes': '24.6', 'Melanocytes': '0.156', 'Fibroblasts': '5.0', 'Peritubular cells': '0.563', 'Endometrial stromal cells': '2.1', 'Ovarian stromal cells': '1.1', 'Undifferentiated cells': '11.5', 'T-cells': '5.6', 'B-cells': '14.2', 'Plasma cells': '3.8', 'Nk-cells': '3.0', 'Granulocytes': '28.5', 'Monocytes': '0.2', 'Macrophages': '3.1', 'Hofbauer cells': '3.8', 'Kupffer cells': '0.6', 'Dendritic cells': '0.4', 'Langerhans cells': '0.320', 'Erythroid cells': '-0.088', 'Adipocytes (Subcutaneous)': '-0.051', 'Adipocytes (Visceral)': '0.077', 'Breast glandular cells (progenitors)': '-0.004', 'Adipocytes (Breast)': '-0.098', 'Colon enterocytes': '0.174', 'Colon enteroendocrine cells': '0.058', 'Enteric glia cells': '0.256', 'Mitotic cells (Colon)': '0.261', 'Mitotic cells (Heart)': '0.388', 'Podocytes': '-0.180', 'Ascending Loop of Henle cells': '0.440', 'Intercalated cells': '-0.198', 'Cholangiocyte': '0.229', 'NK-cells (Liver)': '-0.157', 'Respiratory ciliated cells': '0.081', 'Mitotic cells (Lung)': '-0.135', 'NK-cells (Lung)': '0.541', 'B-cells (Lung)': '0.309', 'Alpha cells': '0.407', 'Beta cells': '0.237', 'Prostate glandular cells': '-0.291', 'Prostate basal glandular cells': '0.100', 'Urothelial cells': '0.296', 'Keratinocyte (other)': '0.642', 'Keratinocyte (granular)': '0.338', 'Hair cortex cells': '-0.410', 'Inner root sheath cells': '-0.355', 'Outer root sheath cells': '-0.300', 'Sebaceous gland cells': '-0.103', 'Eccrine sweat gland cells': '-0.510', 'Adipocytes (Skin)': '-0.465', 'Mitotic cells (Skin)': '0.135', 'Parietal cells': '-0.086', 'Chief cells': '-0.094', 'Gastric mucous cells': '0.430', 'Gastric enteroendocrine cells': '0.079', 'Mitotic cells (Stomach)': '0.463', 'Parafollicular cells': '0.059', 'Thyroid glandular cells': '0.072', 'Mitotic cells (Thyroid)': '0.134', 'Adrenal cortex cells': '0.224', 'Adrenal medulla cells': '0.058', 'Mitotic cells (Adrenal gland)': '0.216', 'Minor salivary glandular cells': '-0.055', 'Minor salivary gland ductal cells': '-0.206', 'Minor salivary gland basal cells': '0.479', 'Mitotic cells (Minor salivary gland)': '0.499', 'Adipocytes (Minor salivary gland)': '0.055', 'Somatotropes': '-0.380', 'Lactotropes': '-0.127', 'Gonadotropes': '0.199', 'Corticotropes': '-0.021', 'Thyrotropes': '0.282', 'Undifferentiated cells (Pituitary gland)': '0.361', 'Mitotic cells (Spleen)': '-0.105', 'Platelets': '-0.223', 'Erythrocytes': '-0.213', 'Hematopoietic stem cells': '-0.325', 'B-cells (Spleen)': '0.698', 'NK-cells (Spleen)': '0.315', 'Amygdala excitatory': '33.7', 'Cerebellar inhibitory': '25.5', 'Cge interneuron': '35.3', 'Deep-layer corticothalamic and 6b': '41.5', 'Deep-layer intratelencephalic': '27.0', 'Deep-layer near-projecting': '47.4', 'Eccentric medium spiny neuron': '36.8', 'Hippocampal ca1-3': '39.0', 'Hippocampal ca4': '26.4', 'Hippocampal dentate gyrus': '34.3', 'Lamp5-lhx6 and chandelier': '35.5', 'Lower rhombic lip': '10.9', 'Mammillary body': '38.2', 'Medium spiny neuron': '33.0', 'Mge interneuron': '33.8', 'Midbrain-derived inhibitory': '49.4', 'Miscellaneous': '34.3', 'Splatter': '28.3', 'Thalamic excitatory': '21.1', 'Upper rhombic lip': '17.8', 'Upper-layer intratelencephalic': '18.0', 'Astrocyte': '16.1', 'Bergmann glia': '97.5', 'Central nervous system macrophage': '61.6', 'Choroid plexus epithelial cell': '10.1', 'Committed oligodendrocyte precursor': '103.5', 'Ependymal cell': '17.9', 'Oligodendrocyte': '203.5', 'Oligodendrocyte precursor cell': '32.9', 'Endothelial cell': '118.2', 'Pericyte': '4.3', 'Vascular associated smooth muscle cell': '26.4', 'Fibroblast': '33.5', 'Leukocyte': '21.9', 'Basophil': '0.9', 'Eosinophil': '0.0', 'Neutrophil': '1.3', 'Classical monocyte': '1.5', 'Non-classical monocyte': '0.5', 'Intermediate monocyte': '0.3', 'T-reg': '5.0', 'GdT-cell': '0.2', 'MAIT T-cell': '7.3', 'Memory CD4 T-cell': '0.3', 'Naive CD4 T-cell': '22.0', 'Memory CD8 T-cell': '0.2', 'Naive CD8 T-cell': '20.4', 'Memory B-cell': '0.7', 'Naive B-cell': '146.3', 'Plasmacytoid DC': '2.7', 'Myeloid DC': '3.0', 'NK-cell': '14.0', 'Total PBMC': '3.6', 'Vd2 gdTCR': '6.2', 'Memory CD4 T-cell Th1\\/Th17': '33.6', 'Memory CD4 T-cell Th17': '34.8', 'Memory CD4 T-cell Th2': '36.4', 'Non-Vd2 gdTCR': '5.2', 'Memory CD4 T-cell Th1': '31.5', 'Memory CD4 T-cell TFH': '26.2', 'Terminal effector memory CD4 T-cell': '8.2', 'Central memory CD8 T-cell': '7.6', 'Effector memory CD8 T-cell': '4.5', 'Terminal effector memory CD8 T-cell': '3.7', 'Non-switched memory B-cell': '9.6', 'Plasmablast': '5.0', 'Switched memory B-cell': '12.0', 'Exhausted memory B-cell': '18.7', 'Progenitor cell': '6.5', 'Memory T-reg': '23.9', 'Naive CD4 T-cell activated': '13.5', 'Naive CD8 T-cell activated': '11.4', 'Naive T-reg': '13.8'}
null
{'Adipose Tissue': 13.92440531561462, 'Adrenal Gland': 4.136121317829458, 'Bladder': 15.531380952380951, 'Blood': 4.600168815931109, 'Blood Vessel': 10.632921348314609, 'Brain': 7.354622180166541, 'Breast': 14.459376906318084, 'Cervix Uteri': 12.101842105263158, 'Colon': 12.646011553273429, 'Esophagus': 10.521013148788928, 'Fallopian Tube': 11.893999999999998, 'Heart': 5.935472706155633, 'Kidney': 6.03491011235955, 'Liver': 2.916461504424779, 'Lung': 28.955254325259514, 'Muscle': 4.290586550435865, 'Nerve': 12.066586429725364, 'Ovary': 5.3553999999999995, 'Pancreas': 2.862465853658537, 'Pituitary': 5.531254416961131, 'Prostate': 10.510702040816328, 'Salivary Gland': 8.320888888888888, 'Skin': 19.81200972913212, 'Small Intestine': 16.868844919786095, 'Spleen': 17.505244813278008, 'Stomach': 9.563259052924792, 'Testis': 3.7670249307479224, 'Thyroid': 14.78259418070444, 'Uterus': 17.346978873239436, 'Vagina': 17.459025641025644}
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RING finger
Part of a complex consisting of TRIM27, USP7 and MAGEL2
null
null
EID1, MAGED4, MAGEF1, SQSTM1, EPC1, CHD4, MAGEL2, PML, EIF3S6, PTPN11, USP7,
PIK3C2B, WASHC1, TBK1, NOD2,ULK1, STK38L
48, 63
null
null
Homomultimerizes
null
88.603957
0.43115
74.343323
0.407644
153
P14373
P38936
33251042
UbiBrowser
TRIM27
MASGSVAECLQQETTCPVCLQYFAEPMMLDCGHNICCACLARCWGTAETNVSCPQCRETFPQRHMRPNRHLANVTQLVKQLRTERPSGPGGEMGVCEKHREPLKLYCEEDQMPICVVCDRSREHRGHSVLPLEEAVEGFKEQIQNQLDHLKRVKDLKKRRRAQGEQARAELLSLTQMEREKIVWEFEQLYHSLKEHEYRLLARLEELDLAIYNSINGAITQFSCNISHLSSLIAQLEEKQQQPTRELLQDIGDTLSRAERIRIPEPWITPPDLQEKIHIFAQKCLFLTESLKQFTEKMQSDMEKIQELREAQLYSVDVTLDPDTAYPSLILSDNLRQVRYSYLQQDLPDNPERFNLFPCVLGSPCFIAGRHYWEVEVGDKAKWTIGVCEDSVCRKGGVTSAPQNGFWAVSLWYGKEYWALTSPMTALPLRTPLQRVGIFLDYDAGEVSFYNVTERCHTFTFSHATFCGPVRPYFSLSYSGGKSAAPLIICPMSGIDGFSGHVGNHGHSMETSP
Homo sapiens
Nucleus, Cytoplasm, Nucleus, PML body, Early endosome, Mitochondrion
Low tissue specificity
{'Ciliated cells': '25.1', 'Basal respiratory cells': '27.3', 'Club cells': '24.7', 'Ionocytes': '23.2', 'Mucus glandular cells': '21.7', 'Serous glandular cells': '33.5', 'Gastric mucus-secreting cells': '23.6', 'Proximal enterocytes': '20.1', 'Paneth cells': '20.0', 'Distal enterocytes': '15.1', 'Intestinal goblet cells': '37.0', 'Exocrine glandular cells': '-0.693', 'Basal prostatic cells': '43.6', 'Prostatic glandular cells': '43.5', 'Breast glandular cells': '0.696', 'Breast myoepithelial cells': '0.544', 'Glandular and luminal cells': '29.8', 'Secretory cells': '37.3', 'Basal keratinocytes': '26.5', 'Suprabasal keratinocytes': '15.7', 'Basal squamous epithelial cells': '34.1', 'Squamous epithelial cells': '21.9', 'Alveolar cells type 1': '-0.038', 'Alveolar cells type 2': '-0.408', 'Salivary duct cells': '18.1', 'Ductal cells': '0.480', 'Hepatocytes': '0.177', 'Cholangiocytes': '22.9', 'Proximal tubular cells': '0.232', 'Distal tubular cells': '18.4', 'Collecting duct cells': '27.2', 'Mesothelial cells': '0.392', 'Sertoli cells': '0.703', 'Granulosa cells': '19.2', 'Enteroendocrine cells': '31.0', 'Pancreatic endocrine cells': '18.7', 'Leydig cells': '0.636', 'Excitatory neurons': '13.0', 'Inhibitory neurons': '12.8', 'Cone photoreceptor cells': '13.6', 'Rod photoreceptor cells': '11.3', 'Bipolar cells': '10.1', 'Horizontal cells': '7.6', 'Astrocytes': '11.1', 'Oligodendrocyte precursor cells': '17.9', 'Oligodendrocytes': '18.4', 'Microglial cells': '16.1', 'Muller glia cells': '12.1', 'Schwann cells': '0.026', 'Spermatogonia': '0.420', 'Spermatocytes': '-0.042', 'Early spermatids': '-0.589', 'Late spermatids': '-0.706', 'Oocytes': '13.2', 'Cytotrophoblasts': '48.8', 'Syncytiotrophoblasts': '50.5', 'Extravillous trophoblasts': '58.8', 'Endothelial cells': '27.6', 'Lymphatic endothelial cells': '18.3', 'Cardiomyocytes': '0.444', 'Skeletal myocytes': '-0.371', 'Smooth muscle cells': '19.7', 'Adipocytes': '20.7', 'Melanocytes': '-0.177', 'Fibroblasts': '22.4', 'Peritubular cells': '0.559', 'Endometrial stromal cells': '27.3', 'Ovarian stromal cells': '24.5', 'Undifferentiated cells': '29.3', 'T-cells': '28.5', 'B-cells': '33.6', 'Plasma cells': '50.4', 'Nk-cells': '25.7', 'Granulocytes': '27.4', 'Monocytes': '32.5', 'Macrophages': '29.6', 'Hofbauer cells': '38.9', 'Kupffer cells': '31.1', 'Dendritic cells': '32.8', 'Langerhans cells': '0.075', 'Erythroid cells': '-0.057', 'Adipocytes (Subcutaneous)': '-0.199', 'Adipocytes (Visceral)': '-0.372', 'Breast glandular cells (progenitors)': '0.493', 'Adipocytes (Breast)': '-0.659', 'Colon enterocytes': '-0.039', 'Colon enteroendocrine cells': '0.155', 'Enteric glia cells': '0.411', 'Mitotic cells (Colon)': '0.069', 'Mitotic cells (Heart)': '0.481', 'Podocytes': '-0.080', 'Ascending Loop of Henle cells': '0.332', 'Intercalated cells': '-0.067', 'Cholangiocyte': '0.283', 'NK-cells (Liver)': '-0.293', 'Respiratory ciliated cells': '0.036', 'Mitotic cells (Lung)': '-0.109', 'NK-cells (Lung)': '0.295', 'B-cells (Lung)': '0.112', 'Alpha cells': '0.335', 'Beta cells': '0.170', 'Prostate glandular cells': '0.251', 'Prostate basal glandular cells': '0.383', 'Urothelial cells': '0.310', 'Keratinocyte (other)': '-0.109', 'Keratinocyte (granular)': '-0.354', 'Hair cortex cells': '0.029', 'Inner root sheath cells': '0.037', 'Outer root sheath cells': '0.284', 'Sebaceous gland cells': '0.136', 'Eccrine sweat gland cells': '0.208', 'Adipocytes (Skin)': '0.020', 'Mitotic cells (Skin)': '0.110', 'Parietal cells': '-0.236', 'Chief cells': '-0.025', 'Gastric mucous cells': '0.098', 'Gastric enteroendocrine cells': '0.091', 'Mitotic cells (Stomach)': '0.263', 'Parafollicular cells': '0.070', 'Thyroid glandular cells': '0.072', 'Mitotic cells (Thyroid)': '0.055', 'Adrenal cortex cells': '0.312', 'Adrenal medulla cells': '-0.104', 'Mitotic cells (Adrenal gland)': '-0.086', 'Minor salivary glandular cells': '0.517', 'Minor salivary gland ductal cells': '0.287', 'Minor salivary gland basal cells': '-0.017', 'Mitotic cells (Minor salivary gland)': '0.010', 'Adipocytes (Minor salivary gland)': '0.057', 'Somatotropes': '0.482', 'Lactotropes': '0.227', 'Gonadotropes': '0.066', 'Corticotropes': '0.019', 'Thyrotropes': '0.026', 'Undifferentiated cells (Pituitary gland)': '-0.250', 'Mitotic cells (Spleen)': '-0.238', 'Platelets': '-0.171', 'Erythrocytes': '-0.096', 'Hematopoietic stem cells': '-0.313', 'B-cells (Spleen)': '0.377', 'NK-cells (Spleen)': '0.278', 'Amygdala excitatory': '29.4', 'Cerebellar inhibitory': '15.3', 'Cge interneuron': '27.6', 'Deep-layer corticothalamic and 6b': '29.3', 'Deep-layer intratelencephalic': '31.8', 'Deep-layer near-projecting': '34.8', 'Eccentric medium spiny neuron': '27.3', 'Hippocampal ca1-3': '26.5', 'Hippocampal ca4': '28.4', 'Hippocampal dentate gyrus': '29.8', 'Lamp5-lhx6 and chandelier': '22.8', 'Lower rhombic lip': '32.2', 'Mammillary body': '18.8', 'Medium spiny neuron': '22.8', 'Mge interneuron': '26.6', 'Midbrain-derived inhibitory': '28.4', 'Miscellaneous': '30.0', 'Splatter': '27.8', 'Thalamic excitatory': '23.9', 'Upper rhombic lip': '24.1', 'Upper-layer intratelencephalic': '28.8', 'Astrocyte': '26.3', 'Bergmann glia': '25.2', 'Central nervous system macrophage': '78.3', 'Choroid plexus epithelial cell': '42.9', 'Committed oligodendrocyte precursor': '33.8', 'Ependymal cell': '20.3', 'Oligodendrocyte': '36.0', 'Oligodendrocyte precursor cell': '32.2', 'Endothelial cell': '58.5', 'Pericyte': '33.4', 'Vascular associated smooth muscle cell': '31.7', 'Fibroblast': '43.5', 'Leukocyte': '58.3', 'Basophil': '20.3', 'Eosinophil': '2.5', 'Neutrophil': '51.3', 'Classical monocyte': '17.4', 'Non-classical monocyte': '33.2', 'Intermediate monocyte': '36.3', 'T-reg': '19.6', 'GdT-cell': '7.2', 'MAIT T-cell': '29.7', 'Memory CD4 T-cell': '10.6', 'Naive CD4 T-cell': '29.7', 'Memory CD8 T-cell': '5.6', 'Naive CD8 T-cell': '28.3', 'Memory B-cell': '7.1', 'Naive B-cell': '18.7', 'Plasmacytoid DC': '27.3', 'Myeloid DC': '30.5', 'NK-cell': '26.2', 'Total PBMC': '23.0', 'Vd2 gdTCR': '19.2', 'Memory CD4 T-cell Th1\\/Th17': '22.6', 'Memory CD4 T-cell Th17': '23.3', 'Memory CD4 T-cell Th2': '23.3', 'Non-Vd2 gdTCR': '18.3', 'Memory CD4 T-cell Th1': '23.8', 'Memory CD4 T-cell TFH': '24.9', 'Terminal effector memory CD4 T-cell': '26.8', 'Central memory CD8 T-cell': '23.4', 'Effector memory CD8 T-cell': '21.7', 'Terminal effector memory CD8 T-cell': '14.3', 'Non-switched memory B-cell': '22.5', 'Plasmablast': '44.1', 'Switched memory B-cell': '25.7', 'Exhausted memory B-cell': '13.9', 'Progenitor cell': '20.6', 'Memory T-reg': '26.0', 'Naive CD4 T-cell activated': '55.5', 'Naive CD8 T-cell activated': '61.3', 'Naive T-reg': '32.5'}
null
{'Adipose Tissue': 30.51002491694352, 'Adrenal Gland': 28.42209302325581, 'Bladder': 42.15761904761904, 'Blood': 47.71387405812702, 'Blood Vessel': 35.17883895131086, 'Brain': 17.082769114307343, 'Breast': 35.04257080610022, 'Cervix Uteri': 56.090526315789475, 'Colon': 26.715078305519896, 'Esophagus': 25.588709342560552, 'Fallopian Tube': 54.83888888888889, 'Heart': 12.228174216027876, 'Kidney': 20.893404494382025, 'Liver': 28.784889380530977, 'Lung': 43.63569204152249, 'Muscle': 13.141891656288918, 'Nerve': 43.2170436187399, 'Ovary': 50.49094444444445, 'Pancreas': 26.43318292682927, 'Pituitary': 49.52038869257951, 'Prostate': 47.70363265306122, 'Salivary Gland': 32.1683950617284, 'Skin': 30.310514648977335, 'Small Intestine': 34.5279679144385, 'Spleen': 56.557759336099586, 'Stomach': 26.06833704735376, 'Testis': 26.19157894736842, 'Thyroid': 45.41816232771823, 'Uterus': 52.2319014084507, 'Vagina': 36.81769230769231}
CDKN1A
MSEPAGDVRQNPCGSKACRRLFGPVDSEQLSRDCDALMAGCIQEARERWNFDFVTETPLEGDFAWERVRGLGLPKLYLPTGPRRGRDELGGGRRPGTSPALLQGTAEEDHVDLSLSCTLVPRSGEQAEGSPGGPGDSQGRKRRQTSMTDFYHSKRRLIFSKRKP
Homo sapiens
Cytoplasm, Nucleus
Low tissue specificity
{'Ciliated cells': '219.2', 'Basal respiratory cells': '269.5', 'Club cells': '189.1', 'Ionocytes': '279.8', 'Mucus glandular cells': '202.6', 'Serous glandular cells': '151.8', 'Gastric mucus-secreting cells': '136.2', 'Proximal enterocytes': '345.5', 'Paneth cells': '170.9', 'Distal enterocytes': '374.3', 'Intestinal goblet cells': '199.6', 'Exocrine glandular cells': '-0.503', 'Basal prostatic cells': '263.3', 'Prostatic glandular cells': '36.9', 'Breast glandular cells': '-0.093', 'Breast myoepithelial cells': '0.013', 'Glandular and luminal cells': '205.8', 'Secretory cells': '211.3', 'Basal keratinocytes': '338.3', 'Suprabasal keratinocytes': '625.4', 'Basal squamous epithelial cells': '564.7', 'Squamous epithelial cells': '599.4', 'Alveolar cells type 1': '-0.006', 'Alveolar cells type 2': '-0.268', 'Salivary duct cells': '211.4', 'Ductal cells': '0.254', 'Hepatocytes': '-0.189', 'Cholangiocytes': '24.8', 'Proximal tubular cells': '0.179', 'Distal tubular cells': '43.0', 'Collecting duct cells': '77.8', 'Mesothelial cells': '-0.166', 'Sertoli cells': '0.547', 'Granulosa cells': '96.6', 'Enteroendocrine cells': '226.3', 'Pancreatic endocrine cells': '156.2', 'Leydig cells': '0.537', 'Excitatory neurons': '0.4', 'Inhibitory neurons': '0.4', 'Cone photoreceptor cells': '0.0', 'Rod photoreceptor cells': '0.8', 'Bipolar cells': '1.2', 'Horizontal cells': '1.3', 'Astrocytes': '0.9', 'Oligodendrocyte precursor cells': '0.0', 'Oligodendrocytes': '0.4', 'Microglial cells': '5.4', 'Muller glia cells': '67.7', 'Schwann cells': '-0.047', 'Spermatogonia': '0.312', 'Spermatocytes': '-0.173', 'Early spermatids': '-0.577', 'Late spermatids': '-0.573', 'Oocytes': '17.6', 'Cytotrophoblasts': '40.0', 'Syncytiotrophoblasts': '172.4', 'Extravillous trophoblasts': '57.7', 'Endothelial cells': '417.4', 'Lymphatic endothelial cells': '198.2', 'Cardiomyocytes': '0.152', 'Skeletal myocytes': '-0.199', 'Smooth muscle cells': '464.8', 'Adipocytes': '577.5', 'Melanocytes': '0.167', 'Fibroblasts': '258.4', 'Peritubular cells': '0.389', 'Endometrial stromal cells': '54.7', 'Ovarian stromal cells': '204.0', 'Undifferentiated cells': '43.2', 'T-cells': '98.5', 'B-cells': '134.5', 'Plasma cells': '326.2', 'Nk-cells': '26.2', 'Granulocytes': '246.5', 'Monocytes': '506.5', 'Macrophages': '288.1', 'Hofbauer cells': '139.3', 'Kupffer cells': '74.3', 'Dendritic cells': '95.0', 'Langerhans cells': '-0.032', 'Erythroid cells': '0.037', 'Adipocytes (Subcutaneous)': '-0.360', 'Adipocytes (Visceral)': '0.069', 'Breast glandular cells (progenitors)': '-0.168', 'Adipocytes (Breast)': '-0.071', 'Colon enterocytes': '-0.005', 'Colon enteroendocrine cells': '-0.041', 'Enteric glia cells': '-0.179', 'Mitotic cells (Colon)': '0.208', 'Mitotic cells (Heart)': '0.293', 'Podocytes': '0.152', 'Ascending Loop of Henle cells': '-0.065', 'Intercalated cells': '-0.145', 'Cholangiocyte': '0.343', 'NK-cells (Liver)': '-0.217', 'Respiratory ciliated cells': '-0.033', 'Mitotic cells (Lung)': '-0.190', 'NK-cells (Lung)': '0.157', 'B-cells (Lung)': '0.184', 'Alpha cells': '0.226', 'Beta cells': '0.160', 'Prostate glandular cells': '-0.244', 'Prostate basal glandular cells': '-0.132', 'Urothelial cells': '0.171', 'Keratinocyte (other)': '0.183', 'Keratinocyte (granular)': '-0.193', 'Hair cortex cells': '0.051', 'Inner root sheath cells': '0.111', 'Outer root sheath cells': '0.189', 'Sebaceous gland cells': '-0.160', 'Eccrine sweat gland cells': '-0.080', 'Adipocytes (Skin)': '-0.298', 'Mitotic cells (Skin)': '0.119', 'Parietal cells': '-0.445', 'Chief cells': '-0.447', 'Gastric mucous cells': '-0.250', 'Gastric enteroendocrine cells': '-0.355', 'Mitotic cells (Stomach)': '-0.063', 'Parafollicular cells': '-0.038', 'Thyroid glandular cells': '-0.105', 'Mitotic cells (Thyroid)': '0.052', 'Adrenal cortex cells': '0.188', 'Adrenal medulla cells': '0.047', 'Mitotic cells (Adrenal gland)': '-0.087', 'Minor salivary glandular cells': '0.239', 'Minor salivary gland ductal cells': '-0.263', 'Minor salivary gland basal cells': '0.564', 'Mitotic cells (Minor salivary gland)': '0.575', 'Adipocytes (Minor salivary gland)': '0.299', 'Somatotropes': '-0.188', 'Lactotropes': '-0.361', 'Gonadotropes': '-0.142', 'Corticotropes': '0.095', 'Thyrotropes': '-0.132', 'Undifferentiated cells (Pituitary gland)': '-0.032', 'Mitotic cells (Spleen)': '-0.164', 'Platelets': '-0.169', 'Erythrocytes': '-0.115', 'Hematopoietic stem cells': '-0.168', 'B-cells (Spleen)': '0.081', 'NK-cells (Spleen)': '-0.017', 'Amygdala excitatory': '0.8', 'Cerebellar inhibitory': '0.3', 'Cge interneuron': '0.4', 'Deep-layer corticothalamic and 6b': '1.0', 'Deep-layer intratelencephalic': '1.2', 'Deep-layer near-projecting': '0.2', 'Eccentric medium spiny neuron': '0.9', 'Hippocampal ca1-3': '0.4', 'Hippocampal ca4': '0.1', 'Hippocampal dentate gyrus': '0.3', 'Lamp5-lhx6 and chandelier': '0.1', 'Lower rhombic lip': '0.1', 'Mammillary body': '0.1', 'Medium spiny neuron': '0.8', 'Mge interneuron': '0.9', 'Midbrain-derived inhibitory': '0.1', 'Miscellaneous': '0.6', 'Splatter': '1.3', 'Thalamic excitatory': '0.3', 'Upper rhombic lip': '0.2', 'Upper-layer intratelencephalic': '1.0', 'Astrocyte': '3.7', 'Bergmann glia': '0.8', 'Central nervous system macrophage': '45.6', 'Choroid plexus epithelial cell': '57.6', 'Committed oligodendrocyte precursor': '1.5', 'Ependymal cell': '24.7', 'Oligodendrocyte': '0.2', 'Oligodendrocyte precursor cell': '0.7', 'Endothelial cell': '56.7', 'Pericyte': '8.8', 'Vascular associated smooth muscle cell': '46.9', 'Fibroblast': '10.3', 'Leukocyte': '8.0', 'Basophil': '2.2', 'Eosinophil': '0.5', 'Neutrophil': '7.6', 'Classical monocyte': '484.7', 'Non-classical monocyte': '172.5', 'Intermediate monocyte': '412.1', 'T-reg': '5.5', 'GdT-cell': '0.5', 'MAIT T-cell': '17.0', 'Memory CD4 T-cell': '1.1', 'Naive CD4 T-cell': '3.1', 'Memory CD8 T-cell': '0.6', 'Naive CD8 T-cell': '3.5', 'Memory B-cell': '20.8', 'Naive B-cell': '99.9', 'Plasmacytoid DC': '81.5', 'Myeloid DC': '344.0', 'NK-cell': '4.9', 'Total PBMC': '259.7', 'Vd2 gdTCR': '12.6', 'Memory CD4 T-cell Th1\\/Th17': '56.7', 'Memory CD4 T-cell Th17': '32.8', 'Memory CD4 T-cell Th2': '24.5', 'Non-Vd2 gdTCR': '14.0', 'Memory CD4 T-cell Th1': '42.0', 'Memory CD4 T-cell TFH': '12.6', 'Terminal effector memory CD4 T-cell': '5.2', 'Central memory CD8 T-cell': '4.1', 'Effector memory CD8 T-cell': '6.5', 'Terminal effector memory CD8 T-cell': '10.8', 'Non-switched memory B-cell': '126.9', 'Plasmablast': '79.6', 'Switched memory B-cell': '92.1', 'Exhausted memory B-cell': '109.4', 'Progenitor cell': '19.9', 'Memory T-reg': '14.0', 'Naive CD4 T-cell activated': '83.2', 'Naive CD8 T-cell activated': '40.7', 'Naive T-reg': '3.2'}
1AXC, 2ZVV, 2ZVW, 4RJF, 5E0U, 6CBI, 6CEJ, 6CIV, 6CIX, 6P8H, 7KQ0, 7KQ1, 8GJF
{'Adipose Tissue': 298.2111129568106, 'Adrenal Gland': 93.4060465116279, 'Bladder': 197.83761904761903, 'Blood': 78.93353928955867, 'Blood Vessel': 448.1661423220974, 'Brain': 26.16142089326268, 'Breast': 190.7731372549019, 'Cervix Uteri': 154.54263157894738, 'Colon': 136.42021822849807, 'Esophagus': 163.55013148788927, 'Fallopian Tube': 361.2999999999999, 'Heart': 85.2329837398374, 'Kidney': 85.09125842696629, 'Liver': 87.66353539823008, 'Lung': 274.2942560553633, 'Muscle': 150.03065255292654, 'Nerve': 203.34387722132473, 'Ovary': 296.445, 'Pancreas': 57.98804878048781, 'Pituitary': 149.13120141342756, 'Prostate': 136.3737551020408, 'Salivary Gland': 92.8451172839506, 'Skin': 328.4404422332781, 'Small Intestine': 143.66491978609625, 'Spleen': 44.88352697095436, 'Stomach': 125.28008356545962, 'Testis': 83.37515235457064, 'Thyroid': 131.78820826952526, 'Uterus': 144.23007042253522, 'Vagina': 215.10339743589745}
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[1.0, 0.93, 0.99, 0.55, 0.46, 0.77, 0.56, 0.53, 0.44, 0.42, 0.36, 0.71, 0.72, 0.01, 0.25, 0.01, 0.39, 0.28, 0.35, 0.72, 0.68, 0.24, 0.08, 0.64, 0.75, 0.02, 0.12, 0.41, 0.02, 0.6, 0.23, 0.43, 0.29, 0.18, 0.0, 0.04, 0.36, 0.68, 0.09, 0.01, 0.49, 0.71, 0.53, 0.08, 0.46, 0.87, 0.43, 0.76, 0.73, 0.74, 0.04, 0.44, 0.01, 0.34, 0.48, 0.44, 0.8, 0.51, 0.7, 0.08, 0.67, 0.57, 0.32, 0.5, 0.34, 0.81, 0.63, 0.18, 0.76, 0.75, 0.14, 0.31, 0.56, 0.43, 0.01, 0.55, 0.53, 0.08, 0.43, 0.4, 0.63, 0.54, 0.72, 0.7, 0.82, 0.89, 0.61, 0.59, 0.99, 0.8, 0.75, 0.83, 0.39, 0.43, 0.61, 0.1, 0.92, 0.71, 0.37, 0.81, 0.46, 0.38, 0.16, 0.48, 0.18, 0.12, 0.0, 0.46, 0.57, 0.42, 0.69, 0.52, 0.44, 0.01, 0.0, 0.51, 0.43, 0.07, 0.36, 0.89, 0.21, 0.91, 0.61, 0.08, 0.78, 0.94, 0.32, 0.34, 0.28, 0.3, 0.47, 0.22, 0.55, 0.55, 0.09, 0.41, 0.68, 0.34, 0.4, 0.62, 0.63, 0.58, 0.57, 0.47, 0.53, 0.59, 0.44, 0.32, 0.49, 0.6, 0.51, 0.61, 0.36, 0.61, 0.48, 0.49, 0.69, 0.57, 0.71, 0.67, 0.7, 0.46, 0.63, 0.49, 0.49, 0.56, 0.39, 0.68, 0.51, 0.56, 0.53, 0.52, 0.59, 0.33, 0.41, 0.47, 0.51, 0.47, 0.54, 0.57, 0.45, 0.58, 0.53, 0.6, 0.71, 0.42, 0.57, 0.48, 0.28, 0.63, 0.56, 0.39, 0.42, 0.6, 0.42, 0.49, 0.44, 0.73, 0.5, 0.33, 0.51, 0.28, 0.6, 0.33, 0.65, 0.52, 0.14, 0.59, 0.56, 0.36, 0.3, 0.65, 0.57, 0.26, 0.39, 0.3, 0.45, 0.08, 0.52, 0.56, 0.63, 0.33, 0.48, 0.58, 0.34, 0.59, 0.57, 0.6, 0.38, 0.51, 0.46, 0.09, 0.51, 0.46, 0.31, 0.33, 0.56, 0.61, 0.11, 0.79, 0.86, 0.32, 0.66, 0.69, 0.89, 0.46, 0.34, 0.68, 0.71, 0.48, 0.26, 0.63, 0.66, 0.02, 0.46, 0.26, 0.44, 0.32, 0.78, 0.73, 0.4, 0.9, 0.98, 0.47, 0.89, 0.8, 0.44, 0.84, 0.43, 0.37, 0.71, 0.56, 0.09, 0.62, 0.63, 0.4, 0.46, 0.59, 0.44, 0.13, 0.47, 0.51, 0.53, 0.42, 0.7, 0.7, 0.44, 0.65, 0.49, 0.33, 0.43, 0.51, 0.51, 0.42, 0.48, 0.5, 0.63, 0.35, 0.57, 0.36, 0.33, 0.7, 0.61, 0.31, 0.42, 0.6, 0.47, 0.03, 0.56, 0.46, 0.02, 0.2, 0.7, 0.38, 0.35, 0.27, 0.48, 0.01, 0.28, 0.0, 0.16, 0.42, 0.54, 0.02, 0.04, 0.13, 0.12, 0.04, 0.02, 0.25, 0.24, 0.24, 0.93, 0.56, 0.27, 0.18, 0.39, 0.01, 0.48, 0.18, 0.21, 0.67, 0.78, 0.73, 0.39, 0.99, 0.45, 0.66, 0.73, 0.22, 0.74, 0.53, 0.04, 0.06, 0.43, 0.56, 0.44, 0.02, 0.02, 0.0, 0.0, 0.0, 0.4, 0.19, 0.48, 0.07, 0.67, 0.53, 0.28, 0.5, 0.16, 0.02, 0.03, 0.13, 0.01, 0.37, 0.01, 0.34, 0.76, 0.03, 0.33, 0.44, 0.01, 0.11, 0.0, 0.0, 0.01, 0.0, 0.14, 0.37, 0.78, 0.07, 0.49, 0.09, 0.35, 0.35, 0.65, 0.35, 0.68, 0.25, 0.03, 0.28, 0.72, 0.39, 0.03, 0.04, 0.04, 0.0, 0.03, 0.01, 0.02, 0.35, 0.75, 0.46, 0.8, 0.39, 0.1, 0.25, 0.0, 0.05, 0.21, 0.66, 0.86, 0.47, 0.39, 0.56, 0.11, 0.88, 0.33, 0.97, 0.41, 0.67, 0.04, 0.34, 0.37, 0.02, 0.0, 0.0, 0.11, 0.0, 0.07, 0.2, 0.73, 0.51, 0.04, 0.37, 0.0, 0.06, 0.0, 0.07, 0.05, 0.15, 0.57, 0.57, 0.49, 0.27, 0.45, 0.18, 0.2, 0.37, 0.06, 0.7, 0.84, 0.12, 0.69, 0.14, 0.72, 0.29, 0.37, 0.0, 0.11, 0.0, 0.04, 0.01, 0.12, 0.08, 0.1, 0.43, 0.35, 0.42, 0.7, 0.87, 0.11, 0.39, 0.44, 0.33, 0.02, 0.3, 0.03, 0.18, 0.68, 0.51, 0.66, 0.65, 0.55, 0.78, 0.65, 0.69, 0.68, 0.79, 0.87, 0.92, 0.62, 0.92, 0.79, 0.75, 0.84, 0.82, 0.89, 0.87, 0.9, 0.88, 0.99]
[57.54, 53.77, 49.2, 54.65, 47.21, 50.18, 51.36, 57.38, 60.34, 59.02, 58.74, 66.7, 62.76, 72.64, 85.27, 85.76, 90.07, 89.08, 88.6, 88.71, 92.47, 94.27, 91.54, 92.49, 93.33, 94.52, 94.92, 96.58, 96.24, 96.62, 96.78, 97.78, 97.38, 96.94, 96.94, 97.21, 97.04, 95.42, 95.72, 96.32, 95.83, 94.85, 95.47, 96.36, 94.83, 93.7, 93.99, 96.23, 96.61, 94.82, 96.08, 94.34, 93.92, 92.26, 92.37, 91.61, 92.18, 94.69, 92.61, 91.05, 91.84, 93.31, 94.39, 93.61, 94.52, 91.02, 88.51, 86.46, 79.31, 69.5, 71.06, 79.0, 84.36, 86.87, 84.55, 85.75, 86.78, 84.16, 79.43, 73.93, 72.5, 58.53, 58.75, 50.85, 45.0, 47.39, 46.55, 44.31, 49.04, 40.77, 42.1, 41.96, 49.04, 54.49, 40.1, 41.62, 44.88, 39.83, 48.69, 39.11, 40.6, 45.92, 33.81, 36.52, 35.52, 41.52, 42.69, 51.4, 44.01, 54.81, 55.66, 49.71, 55.25, 47.45, 51.51, 47.75, 43.71, 46.45, 60.31, 63.94, 55.05, 51.38, 42.11, 43.98, 44.68, 41.84, 41.46, 49.37, 49.4, 49.36, 46.84, 45.02, 57.78, 46.67, 46.47, 51.42, 62.97, 62.03, 45.33, 62.65, 68.04, 72.15, 74.86, 77.44, 74.32, 74.89, 75.34, 71.44, 62.9, 62.6, 60.64, 60.73, 60.71, 62.32, 62.22, 63.79, 58.88, 59.41, 57.55, 57.62, 60.05, 50.89, 58.14, 66.56]
[0.97, 0.93, 0.96, 0.92, 0.91, 0.77, 0.69, 0.78, 0.8, 0.86, 0.4, 0.89, 0.43, 0.95, 0.47, 0.87, 0.77, 0.39, 0.71, 0.71, 0.78, 0.98, 0.42, 0.89, 0.71, 0.59, 0.67, 0.71, 0.39, 0.53, 0.43, 0.54, 0.46, 0.41, 0.53, 0.59, 0.68, 0.54, 0.51, 0.47, 0.59, 0.41, 0.45, 0.63, 0.21, 0.39, 0.69, 0.77, 0.49, 0.09, 0.18, 0.17, 0.45, 0.72, 0.6, 0.57, 0.46, 0.53, 0.33, 0.98, 0.68, 0.95, 0.42, 0.94, 0.45, 0.87, 0.87, 0.55, 0.89, 0.43, 0.94, 0.81, 0.38, 0.56, 0.79, 0.82, 0.73, 0.38, 0.68, 0.92, 0.66, 0.9, 0.78, 0.91, 0.72, 0.97, 0.93, 0.93, 1.0, 0.85, 1.0, 1.0, 1.0, 0.98, 0.94, 0.9, 0.94, 0.91, 0.95, 0.87, 0.97, 1.0, 0.99, 0.93, 0.99, 0.88, 1.0, 0.98, 0.83, 0.97, 0.65, 0.84, 0.61, 0.66, 0.82, 0.71, 0.8, 0.82, 0.84, 0.83, 0.86, 0.95, 0.94, 0.93, 1.0, 0.99, 1.0, 0.99, 1.0, 1.0, 1.0, 1.0, 0.99, 0.98, 0.94, 0.98, 0.95, 0.95, 0.94, 0.93, 0.93, 0.94, 0.92, 0.95, 0.89, 0.68, 0.87, 0.59, 0.83, 0.83, 0.82, 0.84, 0.79, 0.83, 0.87, 0.87, 0.7, 0.82, 0.76, 0.78, 0.93, 0.98, 0.98, 1.0]
RING finger
Part of a complex consisting of TRIM27, USP7 and MAGEL2
null
null
EID1, MAGED4, MAGEF1, SQSTM1, EPC1, CHD4, MAGEL2, PML, EIF3S6, PTPN11, USP7,
PIK3C2B, WASHC1, TBK1, NOD2,ULK1, STK38L
48, 63
null
null
Homomultimerizes
null
88.603957
0.43115
68.75
0.766829
2,849
P14373
P60484
31719796
UbiBrowser
TRIM27
MASGSVAECLQQETTCPVCLQYFAEPMMLDCGHNICCACLARCWGTAETNVSCPQCRETFPQRHMRPNRHLANVTQLVKQLRTERPSGPGGEMGVCEKHREPLKLYCEEDQMPICVVCDRSREHRGHSVLPLEEAVEGFKEQIQNQLDHLKRVKDLKKRRRAQGEQARAELLSLTQMEREKIVWEFEQLYHSLKEHEYRLLARLEELDLAIYNSINGAITQFSCNISHLSSLIAQLEEKQQQPTRELLQDIGDTLSRAERIRIPEPWITPPDLQEKIHIFAQKCLFLTESLKQFTEKMQSDMEKIQELREAQLYSVDVTLDPDTAYPSLILSDNLRQVRYSYLQQDLPDNPERFNLFPCVLGSPCFIAGRHYWEVEVGDKAKWTIGVCEDSVCRKGGVTSAPQNGFWAVSLWYGKEYWALTSPMTALPLRTPLQRVGIFLDYDAGEVSFYNVTERCHTFTFSHATFCGPVRPYFSLSYSGGKSAAPLIICPMSGIDGFSGHVGNHGHSMETSP
Homo sapiens
Nucleus, Cytoplasm, Nucleus, PML body, Early endosome, Mitochondrion
Low tissue specificity
{'Ciliated cells': '25.1', 'Basal respiratory cells': '27.3', 'Club cells': '24.7', 'Ionocytes': '23.2', 'Mucus glandular cells': '21.7', 'Serous glandular cells': '33.5', 'Gastric mucus-secreting cells': '23.6', 'Proximal enterocytes': '20.1', 'Paneth cells': '20.0', 'Distal enterocytes': '15.1', 'Intestinal goblet cells': '37.0', 'Exocrine glandular cells': '-0.693', 'Basal prostatic cells': '43.6', 'Prostatic glandular cells': '43.5', 'Breast glandular cells': '0.696', 'Breast myoepithelial cells': '0.544', 'Glandular and luminal cells': '29.8', 'Secretory cells': '37.3', 'Basal keratinocytes': '26.5', 'Suprabasal keratinocytes': '15.7', 'Basal squamous epithelial cells': '34.1', 'Squamous epithelial cells': '21.9', 'Alveolar cells type 1': '-0.038', 'Alveolar cells type 2': '-0.408', 'Salivary duct cells': '18.1', 'Ductal cells': '0.480', 'Hepatocytes': '0.177', 'Cholangiocytes': '22.9', 'Proximal tubular cells': '0.232', 'Distal tubular cells': '18.4', 'Collecting duct cells': '27.2', 'Mesothelial cells': '0.392', 'Sertoli cells': '0.703', 'Granulosa cells': '19.2', 'Enteroendocrine cells': '31.0', 'Pancreatic endocrine cells': '18.7', 'Leydig cells': '0.636', 'Excitatory neurons': '13.0', 'Inhibitory neurons': '12.8', 'Cone photoreceptor cells': '13.6', 'Rod photoreceptor cells': '11.3', 'Bipolar cells': '10.1', 'Horizontal cells': '7.6', 'Astrocytes': '11.1', 'Oligodendrocyte precursor cells': '17.9', 'Oligodendrocytes': '18.4', 'Microglial cells': '16.1', 'Muller glia cells': '12.1', 'Schwann cells': '0.026', 'Spermatogonia': '0.420', 'Spermatocytes': '-0.042', 'Early spermatids': '-0.589', 'Late spermatids': '-0.706', 'Oocytes': '13.2', 'Cytotrophoblasts': '48.8', 'Syncytiotrophoblasts': '50.5', 'Extravillous trophoblasts': '58.8', 'Endothelial cells': '27.6', 'Lymphatic endothelial cells': '18.3', 'Cardiomyocytes': '0.444', 'Skeletal myocytes': '-0.371', 'Smooth muscle cells': '19.7', 'Adipocytes': '20.7', 'Melanocytes': '-0.177', 'Fibroblasts': '22.4', 'Peritubular cells': '0.559', 'Endometrial stromal cells': '27.3', 'Ovarian stromal cells': '24.5', 'Undifferentiated cells': '29.3', 'T-cells': '28.5', 'B-cells': '33.6', 'Plasma cells': '50.4', 'Nk-cells': '25.7', 'Granulocytes': '27.4', 'Monocytes': '32.5', 'Macrophages': '29.6', 'Hofbauer cells': '38.9', 'Kupffer cells': '31.1', 'Dendritic cells': '32.8', 'Langerhans cells': '0.075', 'Erythroid cells': '-0.057', 'Adipocytes (Subcutaneous)': '-0.199', 'Adipocytes (Visceral)': '-0.372', 'Breast glandular cells (progenitors)': '0.493', 'Adipocytes (Breast)': '-0.659', 'Colon enterocytes': '-0.039', 'Colon enteroendocrine cells': '0.155', 'Enteric glia cells': '0.411', 'Mitotic cells (Colon)': '0.069', 'Mitotic cells (Heart)': '0.481', 'Podocytes': '-0.080', 'Ascending Loop of Henle cells': '0.332', 'Intercalated cells': '-0.067', 'Cholangiocyte': '0.283', 'NK-cells (Liver)': '-0.293', 'Respiratory ciliated cells': '0.036', 'Mitotic cells (Lung)': '-0.109', 'NK-cells (Lung)': '0.295', 'B-cells (Lung)': '0.112', 'Alpha cells': '0.335', 'Beta cells': '0.170', 'Prostate glandular cells': '0.251', 'Prostate basal glandular cells': '0.383', 'Urothelial cells': '0.310', 'Keratinocyte (other)': '-0.109', 'Keratinocyte (granular)': '-0.354', 'Hair cortex cells': '0.029', 'Inner root sheath cells': '0.037', 'Outer root sheath cells': '0.284', 'Sebaceous gland cells': '0.136', 'Eccrine sweat gland cells': '0.208', 'Adipocytes (Skin)': '0.020', 'Mitotic cells (Skin)': '0.110', 'Parietal cells': '-0.236', 'Chief cells': '-0.025', 'Gastric mucous cells': '0.098', 'Gastric enteroendocrine cells': '0.091', 'Mitotic cells (Stomach)': '0.263', 'Parafollicular cells': '0.070', 'Thyroid glandular cells': '0.072', 'Mitotic cells (Thyroid)': '0.055', 'Adrenal cortex cells': '0.312', 'Adrenal medulla cells': '-0.104', 'Mitotic cells (Adrenal gland)': '-0.086', 'Minor salivary glandular cells': '0.517', 'Minor salivary gland ductal cells': '0.287', 'Minor salivary gland basal cells': '-0.017', 'Mitotic cells (Minor salivary gland)': '0.010', 'Adipocytes (Minor salivary gland)': '0.057', 'Somatotropes': '0.482', 'Lactotropes': '0.227', 'Gonadotropes': '0.066', 'Corticotropes': '0.019', 'Thyrotropes': '0.026', 'Undifferentiated cells (Pituitary gland)': '-0.250', 'Mitotic cells (Spleen)': '-0.238', 'Platelets': '-0.171', 'Erythrocytes': '-0.096', 'Hematopoietic stem cells': '-0.313', 'B-cells (Spleen)': '0.377', 'NK-cells (Spleen)': '0.278', 'Amygdala excitatory': '29.4', 'Cerebellar inhibitory': '15.3', 'Cge interneuron': '27.6', 'Deep-layer corticothalamic and 6b': '29.3', 'Deep-layer intratelencephalic': '31.8', 'Deep-layer near-projecting': '34.8', 'Eccentric medium spiny neuron': '27.3', 'Hippocampal ca1-3': '26.5', 'Hippocampal ca4': '28.4', 'Hippocampal dentate gyrus': '29.8', 'Lamp5-lhx6 and chandelier': '22.8', 'Lower rhombic lip': '32.2', 'Mammillary body': '18.8', 'Medium spiny neuron': '22.8', 'Mge interneuron': '26.6', 'Midbrain-derived inhibitory': '28.4', 'Miscellaneous': '30.0', 'Splatter': '27.8', 'Thalamic excitatory': '23.9', 'Upper rhombic lip': '24.1', 'Upper-layer intratelencephalic': '28.8', 'Astrocyte': '26.3', 'Bergmann glia': '25.2', 'Central nervous system macrophage': '78.3', 'Choroid plexus epithelial cell': '42.9', 'Committed oligodendrocyte precursor': '33.8', 'Ependymal cell': '20.3', 'Oligodendrocyte': '36.0', 'Oligodendrocyte precursor cell': '32.2', 'Endothelial cell': '58.5', 'Pericyte': '33.4', 'Vascular associated smooth muscle cell': '31.7', 'Fibroblast': '43.5', 'Leukocyte': '58.3', 'Basophil': '20.3', 'Eosinophil': '2.5', 'Neutrophil': '51.3', 'Classical monocyte': '17.4', 'Non-classical monocyte': '33.2', 'Intermediate monocyte': '36.3', 'T-reg': '19.6', 'GdT-cell': '7.2', 'MAIT T-cell': '29.7', 'Memory CD4 T-cell': '10.6', 'Naive CD4 T-cell': '29.7', 'Memory CD8 T-cell': '5.6', 'Naive CD8 T-cell': '28.3', 'Memory B-cell': '7.1', 'Naive B-cell': '18.7', 'Plasmacytoid DC': '27.3', 'Myeloid DC': '30.5', 'NK-cell': '26.2', 'Total PBMC': '23.0', 'Vd2 gdTCR': '19.2', 'Memory CD4 T-cell Th1\\/Th17': '22.6', 'Memory CD4 T-cell Th17': '23.3', 'Memory CD4 T-cell Th2': '23.3', 'Non-Vd2 gdTCR': '18.3', 'Memory CD4 T-cell Th1': '23.8', 'Memory CD4 T-cell TFH': '24.9', 'Terminal effector memory CD4 T-cell': '26.8', 'Central memory CD8 T-cell': '23.4', 'Effector memory CD8 T-cell': '21.7', 'Terminal effector memory CD8 T-cell': '14.3', 'Non-switched memory B-cell': '22.5', 'Plasmablast': '44.1', 'Switched memory B-cell': '25.7', 'Exhausted memory B-cell': '13.9', 'Progenitor cell': '20.6', 'Memory T-reg': '26.0', 'Naive CD4 T-cell activated': '55.5', 'Naive CD8 T-cell activated': '61.3', 'Naive T-reg': '32.5'}
null
{'Adipose Tissue': 30.51002491694352, 'Adrenal Gland': 28.42209302325581, 'Bladder': 42.15761904761904, 'Blood': 47.71387405812702, 'Blood Vessel': 35.17883895131086, 'Brain': 17.082769114307343, 'Breast': 35.04257080610022, 'Cervix Uteri': 56.090526315789475, 'Colon': 26.715078305519896, 'Esophagus': 25.588709342560552, 'Fallopian Tube': 54.83888888888889, 'Heart': 12.228174216027876, 'Kidney': 20.893404494382025, 'Liver': 28.784889380530977, 'Lung': 43.63569204152249, 'Muscle': 13.141891656288918, 'Nerve': 43.2170436187399, 'Ovary': 50.49094444444445, 'Pancreas': 26.43318292682927, 'Pituitary': 49.52038869257951, 'Prostate': 47.70363265306122, 'Salivary Gland': 32.1683950617284, 'Skin': 30.310514648977335, 'Small Intestine': 34.5279679144385, 'Spleen': 56.557759336099586, 'Stomach': 26.06833704735376, 'Testis': 26.19157894736842, 'Thyroid': 45.41816232771823, 'Uterus': 52.2319014084507, 'Vagina': 36.81769230769231}
PTEN
MTAIIKEIVSRNKRRYQEDGFDLDLTYIYPNIIAMGFPAERLEGVYRNNIDDVVRFLDSKHKNHYKIYNLCAERHYDTAKFNCRVAQYPFEDHNPPQLELIKPFCEDLDQWLSEDDNHVAAIHCKAGKGRTGVMICAYLLHRGKFLKAQEALDFYGEVRTRDKKGVTIPSQRRYVYYYSYLLKNHLDYRPVALLFHKMMFETIPMFSGGTCNPQFVVCQLKVKIYSSNSGPTRREDKFMYFEFPQPLPVCGDIKVEFFHKQNKMLKKDKMFHFWVNTFFIPGPEETSEKVENGSLCDQEIDSICSIERADNDKEYLVLTLTKNDLDKANKDKANRYFSPNFKVKLYFTKTVEEPSNPEASSSTSVTPDVSDNEPDHYRYSDTTDSDPENEPFDEDQHTQITKV
Homo sapiens
Cytoplasm, Nucleus, Nucleus, PML body, Cell projection, dendritic spine, Postsynaptic density, Secreted
Low tissue specificity
{'Ciliated cells': '34.7', 'Basal respiratory cells': '24.4', 'Club cells': '41.2', 'Ionocytes': '19.5', 'Mucus glandular cells': '31.9', 'Serous glandular cells': '53.3', 'Gastric mucus-secreting cells': '39.5', 'Proximal enterocytes': '40.3', 'Paneth cells': '37.7', 'Distal enterocytes': '54.6', 'Intestinal goblet cells': '46.7', 'Exocrine glandular cells': '-0.548', 'Basal prostatic cells': '44.4', 'Prostatic glandular cells': '36.1', 'Breast glandular cells': '-0.229', 'Breast myoepithelial cells': '-0.337', 'Glandular and luminal cells': '27.5', 'Secretory cells': '50.5', 'Basal keratinocytes': '45.9', 'Suprabasal keratinocytes': '50.4', 'Basal squamous epithelial cells': '45.7', 'Squamous epithelial cells': '42.3', 'Alveolar cells type 1': '0.015', 'Alveolar cells type 2': '-0.333', 'Salivary duct cells': '32.9', 'Ductal cells': '0.522', 'Hepatocytes': '0.237', 'Cholangiocytes': '45.8', 'Proximal tubular cells': '0.169', 'Distal tubular cells': '15.4', 'Collecting duct cells': '27.2', 'Mesothelial cells': '-0.026', 'Sertoli cells': '-0.192', 'Granulosa cells': '22.8', 'Enteroendocrine cells': '28.0', 'Pancreatic endocrine cells': '11.9', 'Leydig cells': '-0.043', 'Excitatory neurons': '136.2', 'Inhibitory neurons': '126.7', 'Cone photoreceptor cells': '22.1', 'Rod photoreceptor cells': '54.9', 'Bipolar cells': '84.0', 'Horizontal cells': '47.8', 'Astrocytes': '79.3', 'Oligodendrocyte precursor cells': '130.6', 'Oligodendrocytes': '89.1', 'Microglial cells': '187.9', 'Muller glia cells': '55.2', 'Schwann cells': '0.259', 'Spermatogonia': '0.079', 'Spermatocytes': '0.281', 'Early spermatids': '0.555', 'Late spermatids': '0.136', 'Oocytes': '18.4', 'Cytotrophoblasts': '17.7', 'Syncytiotrophoblasts': '34.4', 'Extravillous trophoblasts': '35.3', 'Endothelial cells': '40.5', 'Lymphatic endothelial cells': '33.6', 'Cardiomyocytes': '0.544', 'Skeletal myocytes': '-0.216', 'Smooth muscle cells': '135.5', 'Adipocytes': '52.5', 'Melanocytes': '0.017', 'Fibroblasts': '90.5', 'Peritubular cells': '0.110', 'Endometrial stromal cells': '95.1', 'Ovarian stromal cells': '33.0', 'Undifferentiated cells': '38.2', 'T-cells': '42.8', 'B-cells': '52.5', 'Plasma cells': '34.4', 'Nk-cells': '44.4', 'Granulocytes': '40.8', 'Monocytes': '216.4', 'Macrophages': '97.1', 'Hofbauer cells': '35.4', 'Kupffer cells': '160.0', 'Dendritic cells': '62.0', 'Langerhans cells': '0.062', 'Erythroid cells': '0.155', 'Adipocytes (Subcutaneous)': '0.348', 'Adipocytes (Visceral)': '0.287', 'Breast glandular cells (progenitors)': '-0.197', 'Adipocytes (Breast)': '0.582', 'Colon enterocytes': '-0.162', 'Colon enteroendocrine cells': '0.365', 'Enteric glia cells': '0.405', 'Mitotic cells (Colon)': '-0.024', 'Mitotic cells (Heart)': '0.534', 'Podocytes': '0.017', 'Ascending Loop of Henle cells': '0.411', 'Intercalated cells': '-0.005', 'Cholangiocyte': '0.283', 'NK-cells (Liver)': '-0.021', 'Respiratory ciliated cells': '-0.001', 'Mitotic cells (Lung)': '-0.068', 'NK-cells (Lung)': '0.106', 'B-cells (Lung)': '0.077', 'Alpha cells': '0.447', 'Beta cells': '0.268', 'Prostate glandular cells': '-0.492', 'Prostate basal glandular cells': '-0.150', 'Urothelial cells': '0.050', 'Keratinocyte (other)': '-0.123', 'Keratinocyte (granular)': '-0.213', 'Hair cortex cells': '0.026', 'Inner root sheath cells': '0.141', 'Outer root sheath cells': '0.232', 'Sebaceous gland cells': '0.175', 'Eccrine sweat gland cells': '0.150', 'Adipocytes (Skin)': '0.226', 'Mitotic cells (Skin)': '0.233', 'Parietal cells': '-0.626', 'Chief cells': '-0.457', 'Gastric mucous cells': '-0.513', 'Gastric enteroendocrine cells': '-0.328', 'Mitotic cells (Stomach)': '-0.071', 'Parafollicular cells': '0.026', 'Thyroid glandular cells': '0.255', 'Mitotic cells (Thyroid)': '0.080', 'Adrenal cortex cells': '0.466', 'Adrenal medulla cells': '0.137', 'Mitotic cells (Adrenal gland)': '0.369', 'Minor salivary glandular cells': '0.369', 'Minor salivary gland ductal cells': '0.083', 'Minor salivary gland basal cells': '0.484', 'Mitotic cells (Minor salivary gland)': '0.482', 'Adipocytes (Minor salivary gland)': '0.435', 'Somatotropes': '-0.164', 'Lactotropes': '-0.103', 'Gonadotropes': '-0.079', 'Corticotropes': '-0.068', 'Thyrotropes': '0.126', 'Undifferentiated cells (Pituitary gland)': '0.285', 'Mitotic cells (Spleen)': '-0.350', 'Platelets': '0.006', 'Erythrocytes': '-0.209', 'Hematopoietic stem cells': '-0.101', 'B-cells (Spleen)': '0.186', 'NK-cells (Spleen)': '0.234', 'Amygdala excitatory': '205.9', 'Cerebellar inhibitory': '243.7', 'Cge interneuron': '187.7', 'Deep-layer corticothalamic and 6b': '208.3', 'Deep-layer intratelencephalic': '187.6', 'Deep-layer near-projecting': '204.7', 'Eccentric medium spiny neuron': '242.6', 'Hippocampal ca1-3': '187.3', 'Hippocampal ca4': '167.1', 'Hippocampal dentate gyrus': '185.4', 'Lamp5-lhx6 and chandelier': '218.8', 'Lower rhombic lip': '174.1', 'Mammillary body': '217.2', 'Medium spiny neuron': '189.9', 'Mge interneuron': '159.6', 'Midbrain-derived inhibitory': '240.2', 'Miscellaneous': '218.2', 'Splatter': '179.9', 'Thalamic excitatory': '190.1', 'Upper rhombic lip': '450.6', 'Upper-layer intratelencephalic': '178.1', 'Astrocyte': '147.6', 'Bergmann glia': '136.2', 'Central nervous system macrophage': '354.6', 'Choroid plexus epithelial cell': '276.7', 'Committed oligodendrocyte precursor': '127.5', 'Ependymal cell': '225.9', 'Oligodendrocyte': '128.3', 'Oligodendrocyte precursor cell': '186.5', 'Endothelial cell': '373.6', 'Pericyte': '1886.3', 'Vascular associated smooth muscle cell': '554.1', 'Fibroblast': '430.3', 'Leukocyte': '255.0', 'Basophil': '134.4', 'Eosinophil': '27.7', 'Neutrophil': '620.5', 'Classical monocyte': '43.7', 'Non-classical monocyte': '46.9', 'Intermediate monocyte': '134.3', 'T-reg': '87.1', 'GdT-cell': '7.2', 'MAIT T-cell': '83.0', 'Memory CD4 T-cell': '7.7', 'Naive CD4 T-cell': '42.3', 'Memory CD8 T-cell': '6.8', 'Naive CD8 T-cell': '37.1', 'Memory B-cell': '8.2', 'Naive B-cell': '52.5', 'Plasmacytoid DC': '91.8', 'Myeloid DC': '153.8', 'NK-cell': '24.3', 'Total PBMC': '138.1', 'Vd2 gdTCR': '80.0', 'Memory CD4 T-cell Th1\\/Th17': '37.1', 'Memory CD4 T-cell Th17': '29.3', 'Memory CD4 T-cell Th2': '33.7', 'Non-Vd2 gdTCR': '86.1', 'Memory CD4 T-cell Th1': '26.7', 'Memory CD4 T-cell TFH': '26.3', 'Terminal effector memory CD4 T-cell': '101.8', 'Central memory CD8 T-cell': '86.1', 'Effector memory CD8 T-cell': '90.1', 'Terminal effector memory CD8 T-cell': '79.6', 'Non-switched memory B-cell': '116.3', 'Plasmablast': '63.7', 'Switched memory B-cell': '94.0', 'Exhausted memory B-cell': '96.1', 'Progenitor cell': '109.9', 'Memory T-reg': '23.9', 'Naive CD4 T-cell activated': '16.8', 'Naive CD8 T-cell activated': '13.6', 'Naive T-reg': '44.2'}
1D5R, 2KYL, 4O1V, 5BUG, 5BZX, 5BZZ, 7JTX, 7JUK, 7JUL, 7JVX, 7PC7, 8X3S
{'Adipose Tissue': 47.57878073089701, 'Adrenal Gland': 18.557232558139532, 'Bladder': 29.20047619047619, 'Blood': 50.926940796555435, 'Blood Vessel': 40.20957303370786, 'Brain': 16.370822104466313, 'Breast': 39.58758169934641, 'Cervix Uteri': 60.99526315789474, 'Colon': 24.48421694480103, 'Esophagus': 22.88764152249135, 'Fallopian Tube': 51.95666666666667, 'Heart': 10.49512775842044, 'Kidney': 13.56823595505618, 'Liver': 11.71562831858407, 'Lung': 33.48531141868512, 'Muscle': 10.279891656288918, 'Nerve': 48.74345718901454, 'Ovary': 34.155277777777776, 'Pancreas': 10.43135975609756, 'Pituitary': 18.875212014134277, 'Prostate': 28.91016326530612, 'Salivary Gland': 14.054104938271603, 'Skin': 22.39354284134881, 'Small Intestine': 22.586106951871656, 'Spleen': 35.62920746887966, 'Stomach': 17.857805013927578, 'Testis': 21.24296398891967, 'Thyroid': 32.27920367534456, 'Uterus': 45.98943661971831, 'Vagina': 41.38442307692308}
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[54.96, 66.83, 73.65, 75.95, 76.26, 79.19, 73.69, 70.17, 72.29, 68.35, 82.31, 82.83, 85.88, 84.71, 90.1, 87.72, 87.15, 87.43, 85.92, 87.94, 90.49, 91.32, 93.23, 94.15, 95.15, 96.96, 97.83, 98.28, 98.15, 97.93, 98.41, 98.75, 98.62, 98.43, 97.35, 94.11, 95.05, 95.11, 91.77, 86.97, 79.01, 74.88, 76.31, 61.73, 66.12, 75.12, 85.33, 88.75, 92.07, 94.61, 93.62, 94.03, 96.18, 95.99, 95.74, 97.44, 97.52, 96.38, 96.24, 96.39, 97.07, 96.48, 96.06, 97.94, 98.47, 98.6, 98.58, 98.74, 98.34, 98.56, 96.62, 94.8, 92.5, 89.17, 92.29, 92.95, 93.51, 94.97, 94.84, 93.02, 94.81, 91.17, 88.68, 94.57, 97.66, 98.28, 98.21, 98.62, 98.13, 98.11, 96.66, 93.68, 94.47, 97.47, 98.21, 98.39, 98.29, 97.84, 97.77, 98.53, 98.8, 98.62, 98.71, 98.87, 98.86, 98.73, 98.81, 98.78, 98.72, 98.64, 98.61, 98.53, 98.01, 98.18, 98.13, 97.51, 97.92, 98.51, 98.6, 98.8, 98.64, 98.76, 97.84, 94.17, 91.11, 90.16, 91.94, 93.17, 96.92, 98.38, 98.57, 98.61, 98.77, 98.89, 98.86, 98.86, 98.87, 98.9, 98.79, 98.67, 98.59, 98.06, 97.84, 98.09, 98.11, 95.25, 96.76, 97.91, 97.73, 98.1, 98.53, 98.36, 98.15, 98.44, 98.42, 97.3, 96.96, 97.11, 96.92, 93.57, 91.89, 92.18, 93.25, 92.01, 94.86, 97.59, 96.54, 97.99, 98.25, 98.48, 98.53, 98.58, 98.34, 98.56, 98.6, 98.24, 98.01, 98.26, 97.83, 96.42, 96.6, 96.85, 95.4, 94.6, 95.22, 95.53, 95.07, 96.35, 94.93, 94.89, 95.7, 96.96, 96.72, 97.71, 97.86, 97.52, 97.75, 98.36, 97.97, 98.33, 96.14, 97.15, 97.58, 97.82, 96.63, 95.37, 92.72, 90.52, 92.09, 93.81, 95.35, 95.59, 97.26, 97.15, 98.39, 98.4, 98.66, 98.52, 97.48, 92.03, 90.52, 96.96, 97.93, 98.16, 98.51, 97.88, 97.34, 94.66, 93.47, 94.28, 96.82, 96.67, 95.53, 94.87, 93.66, 92.15, 94.68, 97.12, 98.07, 98.21, 98.45, 97.93, 97.82, 96.87, 96.38, 97.1, 98.27, 97.98, 98.22, 97.48, 97.52, 98.28, 98.14, 98.61, 98.61, 98.58, 98.58, 97.73, 96.7, 92.72, 85.01, 74.83, 71.41, 73.7, 77.49, 85.37, 89.42, 93.69, 96.44, 98.04, 98.57, 98.68, 98.63, 98.54, 98.1, 97.92, 97.22, 96.1, 95.99, 93.58, 84.37, 65.87, 52.73, 48.62, 44.13, 42.26, 33.04, 34.01, 27.7, 31.59, 26.75, 29.39, 26.3, 28.63, 28.46, 29.56, 42.37, 43.83, 50.56, 53.51, 42.79, 47.82, 60.32, 61.84, 71.7, 69.68, 69.24, 55.31, 60.12, 55.72, 58.12, 61.36, 69.61, 84.47, 92.36, 94.29, 94.81, 95.43, 96.38, 97.06, 97.95, 98.0, 97.35, 97.74, 98.21, 97.73, 97.7, 97.78, 96.71, 96.25, 97.17, 96.05, 97.27, 96.58, 97.03, 97.79, 98.16, 97.23, 97.18, 95.9, 97.97, 97.86, 97.72, 97.15, 97.43, 96.67, 96.59, 95.27, 92.6, 86.75, 71.24, 53.69, 42.57, 34.01, 33.15, 34.31, 33.09, 34.22, 35.06, 40.08, 31.56, 43.71, 34.5, 35.59, 40.71, 38.02, 42.2, 33.76, 41.4, 41.39, 34.74, 40.88, 37.61, 36.21, 35.41, 31.52, 34.71, 28.61, 32.77, 28.96, 27.64, 30.79, 32.78, 32.12, 33.02, 37.87, 36.25, 39.87, 37.68, 32.22, 33.18, 33.82, 36.8, 34.54, 35.84, 37.07, 39.39, 37.84, 38.01, 43.33, 43.92, 40.73, 45.42]
[0.78, 0.53, 0.46, 0.64, 0.37, 0.13, 0.48, 0.64, 0.37, 0.04, 0.56, 0.37, 0.1, 0.43, 0.18, 0.12, 0.53, 0.61, 0.66, 0.87, 0.1, 0.28, 0.0, 0.09, 0.01, 0.12, 0.29, 0.06, 0.3, 0.74, 0.34, 0.04, 0.0, 0.0, 0.0, 0.05, 0.05, 0.0, 0.0, 0.4, 0.91, 0.8, 0.29, 0.07, 0.41, 0.39, 0.18, 0.03, 0.31, 0.01, 0.56, 0.23, 0.0, 0.18, 0.5, 0.0, 0.0, 0.32, 0.64, 0.53, 0.17, 0.73, 0.63, 0.27, 0.0, 0.21, 0.0, 0.0, 0.01, 0.0, 0.0, 0.34, 0.53, 0.19, 0.63, 0.12, 0.52, 0.34, 0.52, 0.34, 0.0, 0.51, 0.64, 0.21, 0.21, 0.13, 0.57, 0.14, 0.49, 0.05, 0.46, 0.33, 0.39, 0.17, 0.1, 0.02, 0.59, 0.04, 0.59, 0.21, 0.0, 0.48, 0.41, 0.0, 0.0, 0.42, 0.24, 0.0, 0.19, 0.58, 0.13, 0.1, 0.6, 0.58, 0.31, 0.95, 0.6, 0.09, 0.02, 0.0, 0.01, 0.0, 0.0, 0.03, 0.17, 0.39, 0.0, 0.31, 0.21, 0.01, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.01, 0.06, 0.01, 0.08, 0.29, 0.56, 0.56, 0.63, 0.18, 0.81, 0.48, 0.03, 0.33, 0.44, 0.0, 0.03, 0.49, 0.26, 0.0, 0.0, 0.46, 0.22, 0.0, 0.02, 0.72, 0.4, 0.62, 0.31, 0.04, 0.04, 0.45, 0.16, 0.09, 0.0, 0.02, 0.23, 0.12, 0.01, 0.0, 0.21, 0.08, 0.05, 0.13, 0.18, 0.09, 0.31, 0.53, 0.48, 0.83, 0.4, 0.79, 0.24, 0.58, 0.58, 0.21, 0.45, 0.0, 0.27, 0.0, 0.17, 0.22, 0.0, 0.1, 0.0, 0.18, 0.19, 0.15, 0.0, 0.38, 0.2, 0.49, 0.95, 0.54, 0.33, 0.13, 0.27, 0.01, 0.18, 0.03, 0.15, 0.0, 0.21, 0.3, 0.47, 0.78, 0.62, 0.68, 0.33, 0.25, 0.59, 0.09, 0.88, 0.42, 0.26, 0.34, 0.53, 0.45, 0.55, 0.41, 0.78, 0.63, 0.33, 0.01, 0.13, 0.01, 0.4, 0.07, 0.81, 0.88, 0.42, 0.1, 0.69, 0.03, 0.28, 0.06, 0.07, 0.0, 0.18, 0.0, 0.13, 0.0, 0.08, 0.05, 0.46, 0.45, 0.85, 0.99, 0.6, 0.97, 0.76, 0.44, 0.38, 0.54, 0.0, 0.01, 0.2, 0.0, 0.13, 0.0, 0.0, 0.0, 0.16, 0.09, 0.02, 0.2, 0.37, 0.37, 0.9, 0.5, 0.67, 0.74, 0.84, 0.96, 0.87, 0.97, 0.97, 1.0, 0.92, 0.9, 0.61, 0.39, 0.71, 0.58, 0.21, 0.36, 0.72, 0.28, 0.2, 0.43, 0.47, 0.3, 0.85, 0.34, 0.99, 0.83, 0.91, 0.56, 0.53, 0.12, 0.08, 0.0, 0.04, 0.19, 0.02, 0.37, 0.06, 0.63, 0.26, 0.0, 0.02, 0.49, 0.0, 0.14, 0.45, 0.11, 0.59, 0.67, 0.35, 0.78, 0.53, 0.02, 0.3, 0.64, 0.69, 0.01, 0.35, 0.0, 0.16, 0.0, 0.08, 0.0, 0.2, 0.48, 0.51, 0.71, 0.94, 0.69, 0.81, 0.95, 0.82, 0.92, 0.92, 1.0, 0.93, 1.0, 0.9, 0.9, 0.94, 0.85, 0.93, 0.86, 0.94, 0.91, 0.82, 0.96, 0.91, 0.97, 0.83, 0.72, 0.9, 0.82, 0.93, 0.73, 0.72, 0.69, 0.82, 0.77, 0.51, 0.43, 0.42, 0.73, 0.58, 0.77, 0.9, 0.83, 0.86, 0.86, 0.84, 0.83, 0.96, 0.89, 0.82, 0.9, 0.83, 0.84, 0.93, 0.95]
RING finger
Part of a complex consisting of TRIM27, USP7 and MAGEL2
null
null
EID1, MAGED4, MAGEF1, SQSTM1, EPC1, CHD4, MAGEL2, PML, EIF3S6, PTPN11, USP7,
PIK3C2B, WASHC1, TBK1, NOD2,ULK1, STK38L
48, 63
null
null
Homomultimerizes
null
88.603957
0.43115
83.247196
0.379404
1,968
P14373
Q15561
33993634
UbiBrowser
TRIM27
MASGSVAECLQQETTCPVCLQYFAEPMMLDCGHNICCACLARCWGTAETNVSCPQCRETFPQRHMRPNRHLANVTQLVKQLRTERPSGPGGEMGVCEKHREPLKLYCEEDQMPICVVCDRSREHRGHSVLPLEEAVEGFKEQIQNQLDHLKRVKDLKKRRRAQGEQARAELLSLTQMEREKIVWEFEQLYHSLKEHEYRLLARLEELDLAIYNSINGAITQFSCNISHLSSLIAQLEEKQQQPTRELLQDIGDTLSRAERIRIPEPWITPPDLQEKIHIFAQKCLFLTESLKQFTEKMQSDMEKIQELREAQLYSVDVTLDPDTAYPSLILSDNLRQVRYSYLQQDLPDNPERFNLFPCVLGSPCFIAGRHYWEVEVGDKAKWTIGVCEDSVCRKGGVTSAPQNGFWAVSLWYGKEYWALTSPMTALPLRTPLQRVGIFLDYDAGEVSFYNVTERCHTFTFSHATFCGPVRPYFSLSYSGGKSAAPLIICPMSGIDGFSGHVGNHGHSMETSP
Homo sapiens
Nucleus, Cytoplasm, Nucleus, PML body, Early endosome, Mitochondrion
Low tissue specificity
{'Ciliated cells': '25.1', 'Basal respiratory cells': '27.3', 'Club cells': '24.7', 'Ionocytes': '23.2', 'Mucus glandular cells': '21.7', 'Serous glandular cells': '33.5', 'Gastric mucus-secreting cells': '23.6', 'Proximal enterocytes': '20.1', 'Paneth cells': '20.0', 'Distal enterocytes': '15.1', 'Intestinal goblet cells': '37.0', 'Exocrine glandular cells': '-0.693', 'Basal prostatic cells': '43.6', 'Prostatic glandular cells': '43.5', 'Breast glandular cells': '0.696', 'Breast myoepithelial cells': '0.544', 'Glandular and luminal cells': '29.8', 'Secretory cells': '37.3', 'Basal keratinocytes': '26.5', 'Suprabasal keratinocytes': '15.7', 'Basal squamous epithelial cells': '34.1', 'Squamous epithelial cells': '21.9', 'Alveolar cells type 1': '-0.038', 'Alveolar cells type 2': '-0.408', 'Salivary duct cells': '18.1', 'Ductal cells': '0.480', 'Hepatocytes': '0.177', 'Cholangiocytes': '22.9', 'Proximal tubular cells': '0.232', 'Distal tubular cells': '18.4', 'Collecting duct cells': '27.2', 'Mesothelial cells': '0.392', 'Sertoli cells': '0.703', 'Granulosa cells': '19.2', 'Enteroendocrine cells': '31.0', 'Pancreatic endocrine cells': '18.7', 'Leydig cells': '0.636', 'Excitatory neurons': '13.0', 'Inhibitory neurons': '12.8', 'Cone photoreceptor cells': '13.6', 'Rod photoreceptor cells': '11.3', 'Bipolar cells': '10.1', 'Horizontal cells': '7.6', 'Astrocytes': '11.1', 'Oligodendrocyte precursor cells': '17.9', 'Oligodendrocytes': '18.4', 'Microglial cells': '16.1', 'Muller glia cells': '12.1', 'Schwann cells': '0.026', 'Spermatogonia': '0.420', 'Spermatocytes': '-0.042', 'Early spermatids': '-0.589', 'Late spermatids': '-0.706', 'Oocytes': '13.2', 'Cytotrophoblasts': '48.8', 'Syncytiotrophoblasts': '50.5', 'Extravillous trophoblasts': '58.8', 'Endothelial cells': '27.6', 'Lymphatic endothelial cells': '18.3', 'Cardiomyocytes': '0.444', 'Skeletal myocytes': '-0.371', 'Smooth muscle cells': '19.7', 'Adipocytes': '20.7', 'Melanocytes': '-0.177', 'Fibroblasts': '22.4', 'Peritubular cells': '0.559', 'Endometrial stromal cells': '27.3', 'Ovarian stromal cells': '24.5', 'Undifferentiated cells': '29.3', 'T-cells': '28.5', 'B-cells': '33.6', 'Plasma cells': '50.4', 'Nk-cells': '25.7', 'Granulocytes': '27.4', 'Monocytes': '32.5', 'Macrophages': '29.6', 'Hofbauer cells': '38.9', 'Kupffer cells': '31.1', 'Dendritic cells': '32.8', 'Langerhans cells': '0.075', 'Erythroid cells': '-0.057', 'Adipocytes (Subcutaneous)': '-0.199', 'Adipocytes (Visceral)': '-0.372', 'Breast glandular cells (progenitors)': '0.493', 'Adipocytes (Breast)': '-0.659', 'Colon enterocytes': '-0.039', 'Colon enteroendocrine cells': '0.155', 'Enteric glia cells': '0.411', 'Mitotic cells (Colon)': '0.069', 'Mitotic cells (Heart)': '0.481', 'Podocytes': '-0.080', 'Ascending Loop of Henle cells': '0.332', 'Intercalated cells': '-0.067', 'Cholangiocyte': '0.283', 'NK-cells (Liver)': '-0.293', 'Respiratory ciliated cells': '0.036', 'Mitotic cells (Lung)': '-0.109', 'NK-cells (Lung)': '0.295', 'B-cells (Lung)': '0.112', 'Alpha cells': '0.335', 'Beta cells': '0.170', 'Prostate glandular cells': '0.251', 'Prostate basal glandular cells': '0.383', 'Urothelial cells': '0.310', 'Keratinocyte (other)': '-0.109', 'Keratinocyte (granular)': '-0.354', 'Hair cortex cells': '0.029', 'Inner root sheath cells': '0.037', 'Outer root sheath cells': '0.284', 'Sebaceous gland cells': '0.136', 'Eccrine sweat gland cells': '0.208', 'Adipocytes (Skin)': '0.020', 'Mitotic cells (Skin)': '0.110', 'Parietal cells': '-0.236', 'Chief cells': '-0.025', 'Gastric mucous cells': '0.098', 'Gastric enteroendocrine cells': '0.091', 'Mitotic cells (Stomach)': '0.263', 'Parafollicular cells': '0.070', 'Thyroid glandular cells': '0.072', 'Mitotic cells (Thyroid)': '0.055', 'Adrenal cortex cells': '0.312', 'Adrenal medulla cells': '-0.104', 'Mitotic cells (Adrenal gland)': '-0.086', 'Minor salivary glandular cells': '0.517', 'Minor salivary gland ductal cells': '0.287', 'Minor salivary gland basal cells': '-0.017', 'Mitotic cells (Minor salivary gland)': '0.010', 'Adipocytes (Minor salivary gland)': '0.057', 'Somatotropes': '0.482', 'Lactotropes': '0.227', 'Gonadotropes': '0.066', 'Corticotropes': '0.019', 'Thyrotropes': '0.026', 'Undifferentiated cells (Pituitary gland)': '-0.250', 'Mitotic cells (Spleen)': '-0.238', 'Platelets': '-0.171', 'Erythrocytes': '-0.096', 'Hematopoietic stem cells': '-0.313', 'B-cells (Spleen)': '0.377', 'NK-cells (Spleen)': '0.278', 'Amygdala excitatory': '29.4', 'Cerebellar inhibitory': '15.3', 'Cge interneuron': '27.6', 'Deep-layer corticothalamic and 6b': '29.3', 'Deep-layer intratelencephalic': '31.8', 'Deep-layer near-projecting': '34.8', 'Eccentric medium spiny neuron': '27.3', 'Hippocampal ca1-3': '26.5', 'Hippocampal ca4': '28.4', 'Hippocampal dentate gyrus': '29.8', 'Lamp5-lhx6 and chandelier': '22.8', 'Lower rhombic lip': '32.2', 'Mammillary body': '18.8', 'Medium spiny neuron': '22.8', 'Mge interneuron': '26.6', 'Midbrain-derived inhibitory': '28.4', 'Miscellaneous': '30.0', 'Splatter': '27.8', 'Thalamic excitatory': '23.9', 'Upper rhombic lip': '24.1', 'Upper-layer intratelencephalic': '28.8', 'Astrocyte': '26.3', 'Bergmann glia': '25.2', 'Central nervous system macrophage': '78.3', 'Choroid plexus epithelial cell': '42.9', 'Committed oligodendrocyte precursor': '33.8', 'Ependymal cell': '20.3', 'Oligodendrocyte': '36.0', 'Oligodendrocyte precursor cell': '32.2', 'Endothelial cell': '58.5', 'Pericyte': '33.4', 'Vascular associated smooth muscle cell': '31.7', 'Fibroblast': '43.5', 'Leukocyte': '58.3', 'Basophil': '20.3', 'Eosinophil': '2.5', 'Neutrophil': '51.3', 'Classical monocyte': '17.4', 'Non-classical monocyte': '33.2', 'Intermediate monocyte': '36.3', 'T-reg': '19.6', 'GdT-cell': '7.2', 'MAIT T-cell': '29.7', 'Memory CD4 T-cell': '10.6', 'Naive CD4 T-cell': '29.7', 'Memory CD8 T-cell': '5.6', 'Naive CD8 T-cell': '28.3', 'Memory B-cell': '7.1', 'Naive B-cell': '18.7', 'Plasmacytoid DC': '27.3', 'Myeloid DC': '30.5', 'NK-cell': '26.2', 'Total PBMC': '23.0', 'Vd2 gdTCR': '19.2', 'Memory CD4 T-cell Th1\\/Th17': '22.6', 'Memory CD4 T-cell Th17': '23.3', 'Memory CD4 T-cell Th2': '23.3', 'Non-Vd2 gdTCR': '18.3', 'Memory CD4 T-cell Th1': '23.8', 'Memory CD4 T-cell TFH': '24.9', 'Terminal effector memory CD4 T-cell': '26.8', 'Central memory CD8 T-cell': '23.4', 'Effector memory CD8 T-cell': '21.7', 'Terminal effector memory CD8 T-cell': '14.3', 'Non-switched memory B-cell': '22.5', 'Plasmablast': '44.1', 'Switched memory B-cell': '25.7', 'Exhausted memory B-cell': '13.9', 'Progenitor cell': '20.6', 'Memory T-reg': '26.0', 'Naive CD4 T-cell activated': '55.5', 'Naive CD8 T-cell activated': '61.3', 'Naive T-reg': '32.5'}
null
{'Adipose Tissue': 30.51002491694352, 'Adrenal Gland': 28.42209302325581, 'Bladder': 42.15761904761904, 'Blood': 47.71387405812702, 'Blood Vessel': 35.17883895131086, 'Brain': 17.082769114307343, 'Breast': 35.04257080610022, 'Cervix Uteri': 56.090526315789475, 'Colon': 26.715078305519896, 'Esophagus': 25.588709342560552, 'Fallopian Tube': 54.83888888888889, 'Heart': 12.228174216027876, 'Kidney': 20.893404494382025, 'Liver': 28.784889380530977, 'Lung': 43.63569204152249, 'Muscle': 13.141891656288918, 'Nerve': 43.2170436187399, 'Ovary': 50.49094444444445, 'Pancreas': 26.43318292682927, 'Pituitary': 49.52038869257951, 'Prostate': 47.70363265306122, 'Salivary Gland': 32.1683950617284, 'Skin': 30.310514648977335, 'Small Intestine': 34.5279679144385, 'Spleen': 56.557759336099586, 'Stomach': 26.06833704735376, 'Testis': 26.19157894736842, 'Thyroid': 45.41816232771823, 'Uterus': 52.2319014084507, 'Vagina': 36.81769230769231}
TEAD4
MEGTAGTITSNEWSSPTSPEGSTASGGSQALDKPIDNDAEGVWSPDIEQSFQEALAIYPPCGRRKIILSDEGKMYGRNELIARYIKLRTGKTRTRKQVSSHIQVLARRKAREIQAKLKDQAAKDKALQSMAAMSSAQIISATAFHSSMALARGPGRPAVSGFWQGALPGQAGTSHDVKPFSQQTYAVQPPLPLPGFESPAGPAPSPSAPPAPPWQGRSVASSKLWMLEFSAFLEQQQDPDTYNKHLFVHIGQSSPSYSDPYLEAVDIRQIYDKFPEKKGGLKDLFERGPSNAFFLVKFWADLNTNIEDEGSSFYGVSSQYESPENMIITCSTKVCSFGKQVVEKVETEYARYENGHYSYRIHRSPLCEYMINFIHKLKHLPEKYMMNSVLENFTILQVVTNRDTQETLLCIAYVFEVSASEHGAQHHIYRLVKE
Homo sapiens
Nucleus
Tissue enhanced (skeletal)
{'Ciliated cells': '3.1', 'Basal respiratory cells': '5.8', 'Club cells': '3.3', 'Ionocytes': '1.8', 'Mucus glandular cells': '4.4', 'Serous glandular cells': '0.2', 'Gastric mucus-secreting cells': '4.1', 'Proximal enterocytes': '38.7', 'Paneth cells': '1.0', 'Distal enterocytes': '2.1', 'Intestinal goblet cells': '4.3', 'Exocrine glandular cells': '-0.769', 'Basal prostatic cells': '23.6', 'Prostatic glandular cells': '1.2', 'Breast glandular cells': '0.070', 'Breast myoepithelial cells': '0.031', 'Glandular and luminal cells': '4.5', 'Secretory cells': '15.8', 'Basal keratinocytes': '9.8', 'Suprabasal keratinocytes': '4.3', 'Basal squamous epithelial cells': '9.1', 'Squamous epithelial cells': '3.8', 'Alveolar cells type 1': '0.130', 'Alveolar cells type 2': '-0.267', 'Salivary duct cells': '6.4', 'Ductal cells': '0.450', 'Hepatocytes': '0.207', 'Cholangiocytes': '5.7', 'Proximal tubular cells': '0.135', 'Distal tubular cells': '9.2', 'Collecting duct cells': '5.8', 'Mesothelial cells': '0.144', 'Sertoli cells': '0.440', 'Granulosa cells': '1.5', 'Enteroendocrine cells': '3.5', 'Pancreatic endocrine cells': '10.2', 'Leydig cells': '0.448', 'Excitatory neurons': '1.5', 'Inhibitory neurons': '0.5', 'Cone photoreceptor cells': '0.0', 'Rod photoreceptor cells': '0.0', 'Bipolar cells': '0.0', 'Horizontal cells': '0.6', 'Astrocytes': '0.0', 'Oligodendrocyte precursor cells': '0.0', 'Oligodendrocytes': '0.4', 'Microglial cells': '3.6', 'Muller glia cells': '0.4', 'Schwann cells': '0.082', 'Spermatogonia': '0.691', 'Spermatocytes': '0.170', 'Early spermatids': '-0.416', 'Late spermatids': '-0.398', 'Oocytes': '12.5', 'Cytotrophoblasts': '53.0', 'Syncytiotrophoblasts': '27.9', 'Extravillous trophoblasts': '13.4', 'Endothelial cells': '26.9', 'Lymphatic endothelial cells': '12.5', 'Cardiomyocytes': '0.071', 'Skeletal myocytes': '0.042', 'Smooth muscle cells': '10.1', 'Adipocytes': '15.8', 'Melanocytes': '0.092', 'Fibroblasts': '7.8', 'Peritubular cells': '0.232', 'Endometrial stromal cells': '5.4', 'Ovarian stromal cells': '1.0', 'Undifferentiated cells': '9.0', 'T-cells': '0.5', 'B-cells': '0.1', 'Plasma cells': '0.7', 'Nk-cells': '0.0', 'Granulocytes': '0.9', 'Monocytes': '0.0', 'Macrophages': '0.7', 'Hofbauer cells': '1.9', 'Kupffer cells': '0.7', 'Dendritic cells': '0.0', 'Langerhans cells': '0.060', 'Erythroid cells': '-0.044', 'Adipocytes (Subcutaneous)': '-0.315', 'Adipocytes (Visceral)': '-0.276', 'Breast glandular cells (progenitors)': '-0.098', 'Adipocytes (Breast)': '-0.151', 'Colon enterocytes': '-0.091', 'Colon enteroendocrine cells': '-0.009', 'Enteric glia cells': '0.182', 'Mitotic cells (Colon)': '0.170', 'Mitotic cells (Heart)': '0.359', 'Podocytes': '-0.068', 'Ascending Loop of Henle cells': '0.124', 'Intercalated cells': '-0.239', 'Cholangiocyte': '0.447', 'NK-cells (Liver)': '-0.317', 'Respiratory ciliated cells': '-0.096', 'Mitotic cells (Lung)': '-0.149', 'NK-cells (Lung)': '0.255', 'B-cells (Lung)': '-0.006', 'Alpha cells': '0.174', 'Beta cells': '0.101', 'Prostate glandular cells': '-0.340', 'Prostate basal glandular cells': '0.017', 'Urothelial cells': '0.103', 'Keratinocyte (other)': '0.281', 'Keratinocyte (granular)': '0.628', 'Hair cortex cells': '-0.265', 'Inner root sheath cells': '-0.282', 'Outer root sheath cells': '-0.520', 'Sebaceous gland cells': '-0.290', 'Eccrine sweat gland cells': '-0.388', 'Adipocytes (Skin)': '-0.222', 'Mitotic cells (Skin)': '-0.185', 'Parietal cells': '-0.704', 'Chief cells': '-0.573', 'Gastric mucous cells': '-0.354', 'Gastric enteroendocrine cells': '-0.381', 'Mitotic cells (Stomach)': '0.118', 'Parafollicular cells': '0.021', 'Thyroid glandular cells': '0.217', 'Mitotic cells (Thyroid)': '-0.216', 'Adrenal cortex cells': '0.240', 'Adrenal medulla cells': '0.066', 'Mitotic cells (Adrenal gland)': '0.041', 'Minor salivary glandular cells': '0.477', 'Minor salivary gland ductal cells': '-0.179', 'Minor salivary gland basal cells': '0.294', 'Mitotic cells (Minor salivary gland)': '0.479', 'Adipocytes (Minor salivary gland)': '0.233', 'Somatotropes': '-0.052', 'Lactotropes': '-0.377', 'Gonadotropes': '-0.279', 'Corticotropes': '-0.170', 'Thyrotropes': '-0.259', 'Undifferentiated cells (Pituitary gland)': '0.140', 'Mitotic cells (Spleen)': '-0.347', 'Platelets': '-0.172', 'Erythrocytes': '-0.100', 'Hematopoietic stem cells': '-0.319', 'B-cells (Spleen)': '0.019', 'NK-cells (Spleen)': '0.156', 'Amygdala excitatory': '0.7', 'Cerebellar inhibitory': '0.4', 'Cge interneuron': '0.5', 'Deep-layer corticothalamic and 6b': '0.3', 'Deep-layer intratelencephalic': '0.8', 'Deep-layer near-projecting': '0.4', 'Eccentric medium spiny neuron': '0.4', 'Hippocampal ca1-3': '0.7', 'Hippocampal ca4': '0.5', 'Hippocampal dentate gyrus': '2.1', 'Lamp5-lhx6 and chandelier': '1.0', 'Lower rhombic lip': '0.4', 'Mammillary body': '0.4', 'Medium spiny neuron': '0.9', 'Mge interneuron': '1.0', 'Midbrain-derived inhibitory': '0.2', 'Miscellaneous': '0.5', 'Splatter': '0.4', 'Thalamic excitatory': '1.9', 'Upper rhombic lip': '3.0', 'Upper-layer intratelencephalic': '1.4', 'Astrocyte': '0.5', 'Bergmann glia': '0.6', 'Central nervous system macrophage': '0.4', 'Choroid plexus epithelial cell': '7.1', 'Committed oligodendrocyte precursor': '0.9', 'Ependymal cell': '0.5', 'Oligodendrocyte': '0.4', 'Oligodendrocyte precursor cell': '0.3', 'Endothelial cell': '46.5', 'Pericyte': '1.3', 'Vascular associated smooth muscle cell': '15.7', 'Fibroblast': '0.6', 'Leukocyte': '0.6', 'Basophil': '0.0', 'Eosinophil': '0.0', 'Neutrophil': '0.0', 'Classical monocyte': '0.0', 'Non-classical monocyte': '0.0', 'Intermediate monocyte': '0.0', 'T-reg': '0.0', 'GdT-cell': '0.0', 'MAIT T-cell': '0.0', 'Memory CD4 T-cell': '0.0', 'Naive CD4 T-cell': '0.0', 'Memory CD8 T-cell': '0.0', 'Naive CD8 T-cell': '0.0', 'Memory B-cell': '0.0', 'Naive B-cell': '0.0', 'Plasmacytoid DC': '0.0', 'Myeloid DC': '0.0', 'NK-cell': '0.0', 'Total PBMC': '0.0', 'Vd2 gdTCR': '0.0', 'Memory CD4 T-cell TFH': '0.0', 'Memory CD4 T-cell Th2': '0.0', 'Memory CD4 T-cell Th17': '0.0', 'Memory CD4 T-cell Th1\\/Th17': '0.0', 'Non-Vd2 gdTCR': '0.0', 'Memory CD4 T-cell Th1': '0.0', 'Terminal effector memory CD4 T-cell': '0.0', 'Central memory CD8 T-cell': '0.0', 'Effector memory CD8 T-cell': '0.0', 'Terminal effector memory CD8 T-cell': '0.0', 'Switched memory B-cell': '0.0', 'Plasmablast': '0.1', 'Non-switched memory B-cell': '0.0', 'Exhausted memory B-cell': '0.0', 'Progenitor cell': '0.4', 'Memory T-reg': '0.0', 'Naive CD4 T-cell activated': '0.0', 'Naive CD8 T-cell activated': '0.0', 'Naive T-reg': '0.0'}
5GZB, 5NO6, 5OAQ, 6GE3, 6GE4, 6GE5, 6GE6, 6GEC, 6GEE, 6GEG, 6GEI, 6GEK, 6HIK, 6Q2X, 6Q36, 6SEN, 6SEO, 8A8R, 8C17, 8CAA
{'Adipose Tissue': 16.1472134551495, 'Adrenal Gland': 4.910872868217054, 'Bladder': 14.629142857142856, 'Blood': 0.9515241550053822, 'Blood Vessel': 14.7528202247191, 'Brain': 2.241403077214232, 'Breast': 15.377732026143793, 'Cervix Uteri': 14.459526315789471, 'Colon': 8.775590500641849, 'Esophagus': 10.58124152249135, 'Fallopian Tube': 13.580222222222222, 'Heart': 9.483378397212544, 'Kidney': 13.508483146067414, 'Liver': 2.5858231415929205, 'Lung': 37.443783737024226, 'Muscle': 67.35317559153175, 'Nerve': 18.754788368336023, 'Ovary': 6.817105555555555, 'Pancreas': 24.40280182926829, 'Pituitary': 4.685437809187279, 'Prostate': 11.981612244897958, 'Salivary Gland': 9.059822839506172, 'Skin': 18.05478220011056, 'Small Intestine': 6.846967914438503, 'Spleen': 11.155522821576763, 'Stomach': 8.489270194986073, 'Testis': 6.511537396121883, 'Thyroid': 37.58748698315467, 'Uterus': 16.448070422535213, 'Vagina': 10.35948717948718}
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RING finger
Part of a complex consisting of TRIM27, USP7 and MAGEL2
null
null
EID1, MAGED4, MAGEF1, SQSTM1, EPC1, CHD4, MAGEL2, PML, EIF3S6, PTPN11, USP7,
PIK3C2B, WASHC1, TBK1, NOD2,ULK1, STK38L
48, 63
null
null
Homomultimerizes
null
88.603957
0.43115
75.042903
0.501982
1,830
P14373
Q9UHD2
29688809
UbiBrowser
TRIM27
MASGSVAECLQQETTCPVCLQYFAEPMMLDCGHNICCACLARCWGTAETNVSCPQCRETFPQRHMRPNRHLANVTQLVKQLRTERPSGPGGEMGVCEKHREPLKLYCEEDQMPICVVCDRSREHRGHSVLPLEEAVEGFKEQIQNQLDHLKRVKDLKKRRRAQGEQARAELLSLTQMEREKIVWEFEQLYHSLKEHEYRLLARLEELDLAIYNSINGAITQFSCNISHLSSLIAQLEEKQQQPTRELLQDIGDTLSRAERIRIPEPWITPPDLQEKIHIFAQKCLFLTESLKQFTEKMQSDMEKIQELREAQLYSVDVTLDPDTAYPSLILSDNLRQVRYSYLQQDLPDNPERFNLFPCVLGSPCFIAGRHYWEVEVGDKAKWTIGVCEDSVCRKGGVTSAPQNGFWAVSLWYGKEYWALTSPMTALPLRTPLQRVGIFLDYDAGEVSFYNVTERCHTFTFSHATFCGPVRPYFSLSYSGGKSAAPLIICPMSGIDGFSGHVGNHGHSMETSP
Homo sapiens
Nucleus, Cytoplasm, Nucleus, PML body, Early endosome, Mitochondrion
Low tissue specificity
{'Ciliated cells': '25.1', 'Basal respiratory cells': '27.3', 'Club cells': '24.7', 'Ionocytes': '23.2', 'Mucus glandular cells': '21.7', 'Serous glandular cells': '33.5', 'Gastric mucus-secreting cells': '23.6', 'Proximal enterocytes': '20.1', 'Paneth cells': '20.0', 'Distal enterocytes': '15.1', 'Intestinal goblet cells': '37.0', 'Exocrine glandular cells': '-0.693', 'Basal prostatic cells': '43.6', 'Prostatic glandular cells': '43.5', 'Breast glandular cells': '0.696', 'Breast myoepithelial cells': '0.544', 'Glandular and luminal cells': '29.8', 'Secretory cells': '37.3', 'Basal keratinocytes': '26.5', 'Suprabasal keratinocytes': '15.7', 'Basal squamous epithelial cells': '34.1', 'Squamous epithelial cells': '21.9', 'Alveolar cells type 1': '-0.038', 'Alveolar cells type 2': '-0.408', 'Salivary duct cells': '18.1', 'Ductal cells': '0.480', 'Hepatocytes': '0.177', 'Cholangiocytes': '22.9', 'Proximal tubular cells': '0.232', 'Distal tubular cells': '18.4', 'Collecting duct cells': '27.2', 'Mesothelial cells': '0.392', 'Sertoli cells': '0.703', 'Granulosa cells': '19.2', 'Enteroendocrine cells': '31.0', 'Pancreatic endocrine cells': '18.7', 'Leydig cells': '0.636', 'Excitatory neurons': '13.0', 'Inhibitory neurons': '12.8', 'Cone photoreceptor cells': '13.6', 'Rod photoreceptor cells': '11.3', 'Bipolar cells': '10.1', 'Horizontal cells': '7.6', 'Astrocytes': '11.1', 'Oligodendrocyte precursor cells': '17.9', 'Oligodendrocytes': '18.4', 'Microglial cells': '16.1', 'Muller glia cells': '12.1', 'Schwann cells': '0.026', 'Spermatogonia': '0.420', 'Spermatocytes': '-0.042', 'Early spermatids': '-0.589', 'Late spermatids': '-0.706', 'Oocytes': '13.2', 'Cytotrophoblasts': '48.8', 'Syncytiotrophoblasts': '50.5', 'Extravillous trophoblasts': '58.8', 'Endothelial cells': '27.6', 'Lymphatic endothelial cells': '18.3', 'Cardiomyocytes': '0.444', 'Skeletal myocytes': '-0.371', 'Smooth muscle cells': '19.7', 'Adipocytes': '20.7', 'Melanocytes': '-0.177', 'Fibroblasts': '22.4', 'Peritubular cells': '0.559', 'Endometrial stromal cells': '27.3', 'Ovarian stromal cells': '24.5', 'Undifferentiated cells': '29.3', 'T-cells': '28.5', 'B-cells': '33.6', 'Plasma cells': '50.4', 'Nk-cells': '25.7', 'Granulocytes': '27.4', 'Monocytes': '32.5', 'Macrophages': '29.6', 'Hofbauer cells': '38.9', 'Kupffer cells': '31.1', 'Dendritic cells': '32.8', 'Langerhans cells': '0.075', 'Erythroid cells': '-0.057', 'Adipocytes (Subcutaneous)': '-0.199', 'Adipocytes (Visceral)': '-0.372', 'Breast glandular cells (progenitors)': '0.493', 'Adipocytes (Breast)': '-0.659', 'Colon enterocytes': '-0.039', 'Colon enteroendocrine cells': '0.155', 'Enteric glia cells': '0.411', 'Mitotic cells (Colon)': '0.069', 'Mitotic cells (Heart)': '0.481', 'Podocytes': '-0.080', 'Ascending Loop of Henle cells': '0.332', 'Intercalated cells': '-0.067', 'Cholangiocyte': '0.283', 'NK-cells (Liver)': '-0.293', 'Respiratory ciliated cells': '0.036', 'Mitotic cells (Lung)': '-0.109', 'NK-cells (Lung)': '0.295', 'B-cells (Lung)': '0.112', 'Alpha cells': '0.335', 'Beta cells': '0.170', 'Prostate glandular cells': '0.251', 'Prostate basal glandular cells': '0.383', 'Urothelial cells': '0.310', 'Keratinocyte (other)': '-0.109', 'Keratinocyte (granular)': '-0.354', 'Hair cortex cells': '0.029', 'Inner root sheath cells': '0.037', 'Outer root sheath cells': '0.284', 'Sebaceous gland cells': '0.136', 'Eccrine sweat gland cells': '0.208', 'Adipocytes (Skin)': '0.020', 'Mitotic cells (Skin)': '0.110', 'Parietal cells': '-0.236', 'Chief cells': '-0.025', 'Gastric mucous cells': '0.098', 'Gastric enteroendocrine cells': '0.091', 'Mitotic cells (Stomach)': '0.263', 'Parafollicular cells': '0.070', 'Thyroid glandular cells': '0.072', 'Mitotic cells (Thyroid)': '0.055', 'Adrenal cortex cells': '0.312', 'Adrenal medulla cells': '-0.104', 'Mitotic cells (Adrenal gland)': '-0.086', 'Minor salivary glandular cells': '0.517', 'Minor salivary gland ductal cells': '0.287', 'Minor salivary gland basal cells': '-0.017', 'Mitotic cells (Minor salivary gland)': '0.010', 'Adipocytes (Minor salivary gland)': '0.057', 'Somatotropes': '0.482', 'Lactotropes': '0.227', 'Gonadotropes': '0.066', 'Corticotropes': '0.019', 'Thyrotropes': '0.026', 'Undifferentiated cells (Pituitary gland)': '-0.250', 'Mitotic cells (Spleen)': '-0.238', 'Platelets': '-0.171', 'Erythrocytes': '-0.096', 'Hematopoietic stem cells': '-0.313', 'B-cells (Spleen)': '0.377', 'NK-cells (Spleen)': '0.278', 'Amygdala excitatory': '29.4', 'Cerebellar inhibitory': '15.3', 'Cge interneuron': '27.6', 'Deep-layer corticothalamic and 6b': '29.3', 'Deep-layer intratelencephalic': '31.8', 'Deep-layer near-projecting': '34.8', 'Eccentric medium spiny neuron': '27.3', 'Hippocampal ca1-3': '26.5', 'Hippocampal ca4': '28.4', 'Hippocampal dentate gyrus': '29.8', 'Lamp5-lhx6 and chandelier': '22.8', 'Lower rhombic lip': '32.2', 'Mammillary body': '18.8', 'Medium spiny neuron': '22.8', 'Mge interneuron': '26.6', 'Midbrain-derived inhibitory': '28.4', 'Miscellaneous': '30.0', 'Splatter': '27.8', 'Thalamic excitatory': '23.9', 'Upper rhombic lip': '24.1', 'Upper-layer intratelencephalic': '28.8', 'Astrocyte': '26.3', 'Bergmann glia': '25.2', 'Central nervous system macrophage': '78.3', 'Choroid plexus epithelial cell': '42.9', 'Committed oligodendrocyte precursor': '33.8', 'Ependymal cell': '20.3', 'Oligodendrocyte': '36.0', 'Oligodendrocyte precursor cell': '32.2', 'Endothelial cell': '58.5', 'Pericyte': '33.4', 'Vascular associated smooth muscle cell': '31.7', 'Fibroblast': '43.5', 'Leukocyte': '58.3', 'Basophil': '20.3', 'Eosinophil': '2.5', 'Neutrophil': '51.3', 'Classical monocyte': '17.4', 'Non-classical monocyte': '33.2', 'Intermediate monocyte': '36.3', 'T-reg': '19.6', 'GdT-cell': '7.2', 'MAIT T-cell': '29.7', 'Memory CD4 T-cell': '10.6', 'Naive CD4 T-cell': '29.7', 'Memory CD8 T-cell': '5.6', 'Naive CD8 T-cell': '28.3', 'Memory B-cell': '7.1', 'Naive B-cell': '18.7', 'Plasmacytoid DC': '27.3', 'Myeloid DC': '30.5', 'NK-cell': '26.2', 'Total PBMC': '23.0', 'Vd2 gdTCR': '19.2', 'Memory CD4 T-cell Th1\\/Th17': '22.6', 'Memory CD4 T-cell Th17': '23.3', 'Memory CD4 T-cell Th2': '23.3', 'Non-Vd2 gdTCR': '18.3', 'Memory CD4 T-cell Th1': '23.8', 'Memory CD4 T-cell TFH': '24.9', 'Terminal effector memory CD4 T-cell': '26.8', 'Central memory CD8 T-cell': '23.4', 'Effector memory CD8 T-cell': '21.7', 'Terminal effector memory CD8 T-cell': '14.3', 'Non-switched memory B-cell': '22.5', 'Plasmablast': '44.1', 'Switched memory B-cell': '25.7', 'Exhausted memory B-cell': '13.9', 'Progenitor cell': '20.6', 'Memory T-reg': '26.0', 'Naive CD4 T-cell activated': '55.5', 'Naive CD8 T-cell activated': '61.3', 'Naive T-reg': '32.5'}
null
{'Adipose Tissue': 30.51002491694352, 'Adrenal Gland': 28.42209302325581, 'Bladder': 42.15761904761904, 'Blood': 47.71387405812702, 'Blood Vessel': 35.17883895131086, 'Brain': 17.082769114307343, 'Breast': 35.04257080610022, 'Cervix Uteri': 56.090526315789475, 'Colon': 26.715078305519896, 'Esophagus': 25.588709342560552, 'Fallopian Tube': 54.83888888888889, 'Heart': 12.228174216027876, 'Kidney': 20.893404494382025, 'Liver': 28.784889380530977, 'Lung': 43.63569204152249, 'Muscle': 13.141891656288918, 'Nerve': 43.2170436187399, 'Ovary': 50.49094444444445, 'Pancreas': 26.43318292682927, 'Pituitary': 49.52038869257951, 'Prostate': 47.70363265306122, 'Salivary Gland': 32.1683950617284, 'Skin': 30.310514648977335, 'Small Intestine': 34.5279679144385, 'Spleen': 56.557759336099586, 'Stomach': 26.06833704735376, 'Testis': 26.19157894736842, 'Thyroid': 45.41816232771823, 'Uterus': 52.2319014084507, 'Vagina': 36.81769230769231}
TBK1
MQSTSNHLWLLSDILGQGATANVFRGRHKKTGDLFAIKVFNNISFLRPVDVQMREFEVLKKLNHKNIVKLFAIEEETTTRHKVLIMEFCPCGSLYTVLEEPSNAYGLPESEFLIVLRDVVGGMNHLRENGIVHRDIKPGNIMRVIGEDGQSVYKLTDFGAARELEDDEQFVSLYGTEEYLHPDMYERAVLRKDHQKKYGATVDLWSIGVTFYHAATGSLPFRPFEGPRRNKEVMYKIITGKPSGAISGVQKAENGPIDWSGDMPVSCSLSRGLQVLLTPVLANILEADQEKCWGFDQFFAETSDILHRMVIHVFSLQQMTAHKIYIHSYNTATIFHELVYKQTKIISSNQELIYEGRRLVLEPGRLAQHFPKTTEENPIFVVSREPLNTIGLIYEKISLPKVHPRYDLDGDASMAKAITGVVCYACRIASTLLLYQELMRKGIRWLIELIKDDYNETVHKKTEVVITLDFCIRNIEKTVKVYEKLMKINLEAAELGEISDIHTKLLRLSSSQGTIETSLQDIDSRLSPGGSLADAWAHQEGTHPKDRNVEKLQVLLNCMTEIYYQFKKDKAERRLAYNEEQIHKFDKQKLYYHATKAMTHFTDECVKKYEAFLNKSEEWIRKMLHLRKQLLSLTNQCFDIEEEVSKYQEYTNELQETLPQKMFTASSGIKHTMTPIYPSSNTLVEMTLGMKKLKEEMEGVVKELAENNHILERFGSLTMDGGLRNVDCL
Homo sapiens
Cytoplasm
Low tissue specificity
{'Ciliated cells': '34.3', 'Basal respiratory cells': '48.3', 'Club cells': '39.6', 'Ionocytes': '82.8', 'Mucus glandular cells': '57.4', 'Serous glandular cells': '23.5', 'Gastric mucus-secreting cells': '18.9', 'Proximal enterocytes': '30.4', 'Paneth cells': '31.8', 'Distal enterocytes': '22.0', 'Intestinal goblet cells': '23.2', 'Exocrine glandular cells': '-0.684', 'Basal prostatic cells': '30.5', 'Prostatic glandular cells': '42.2', 'Breast glandular cells': '0.343', 'Breast myoepithelial cells': '0.354', 'Glandular and luminal cells': '54.0', 'Secretory cells': '31.8', 'Basal keratinocytes': '21.6', 'Suprabasal keratinocytes': '25.1', 'Basal squamous epithelial cells': '15.3', 'Squamous epithelial cells': '17.8', 'Alveolar cells type 1': '0.208', 'Alveolar cells type 2': '-0.095', 'Salivary duct cells': '33.6', 'Ductal cells': '0.630', 'Hepatocytes': '0.327', 'Cholangiocytes': '17.2', 'Proximal tubular cells': '0.176', 'Distal tubular cells': '9.2', 'Collecting duct cells': '35.0', 'Mesothelial cells': '0.267', 'Sertoli cells': '-0.066', 'Granulosa cells': '27.1', 'Enteroendocrine cells': '21.7', 'Pancreatic endocrine cells': '18.7', 'Leydig cells': '-0.120', 'Excitatory neurons': '48.8', 'Inhibitory neurons': '40.4', 'Cone photoreceptor cells': '32.3', 'Rod photoreceptor cells': '49.1', 'Bipolar cells': '42.6', 'Horizontal cells': '51.0', 'Astrocytes': '26.9', 'Oligodendrocyte precursor cells': '36.8', 'Oligodendrocytes': '48.7', 'Microglial cells': '44.7', 'Muller glia cells': '19.6', 'Schwann cells': '0.105', 'Spermatogonia': '0.177', 'Spermatocytes': '0.581', 'Early spermatids': '0.644', 'Late spermatids': '0.071', 'Oocytes': '14.0', 'Cytotrophoblasts': '49.3', 'Syncytiotrophoblasts': '168.8', 'Extravillous trophoblasts': '77.1', 'Endothelial cells': '37.9', 'Lymphatic endothelial cells': '52.9', 'Cardiomyocytes': '0.540', 'Skeletal myocytes': '-0.323', 'Smooth muscle cells': '30.0', 'Adipocytes': '43.6', 'Melanocytes': '0.001', 'Fibroblasts': '32.4', 'Peritubular cells': '-0.033', 'Endometrial stromal cells': '32.9', 'Ovarian stromal cells': '35.3', 'Undifferentiated cells': '17.7', 'T-cells': '40.1', 'B-cells': '39.1', 'Plasma cells': '29.5', 'Nk-cells': '80.7', 'Granulocytes': '74.0', 'Monocytes': '195.8', 'Macrophages': '58.7', 'Hofbauer cells': '37.4', 'Kupffer cells': '40.6', 'Dendritic cells': '20.4', 'Langerhans cells': '0.124', 'Erythroid cells': '-0.045', 'Adipocytes (Subcutaneous)': '-0.279', 'Adipocytes (Visceral)': '-0.332', 'Breast glandular cells (progenitors)': '0.203', 'Adipocytes (Breast)': '-0.318', 'Colon enterocytes': '-0.084', 'Colon enteroendocrine cells': '0.277', 'Enteric glia cells': '-0.056', 'Mitotic cells (Colon)': '0.037', 'Mitotic cells (Heart)': '0.503', 'Podocytes': '-0.027', 'Ascending Loop of Henle cells': '0.319', 'Intercalated cells': '-0.100', 'Cholangiocyte': '0.343', 'NK-cells (Liver)': '-0.315', 'Respiratory ciliated cells': '-0.020', 'Mitotic cells (Lung)': '-0.107', 'NK-cells (Lung)': '0.367', 'B-cells (Lung)': '0.135', 'Alpha cells': '0.406', 'Beta cells': '0.201', 'Prostate glandular cells': '-0.033', 'Prostate basal glandular cells': '0.278', 'Urothelial cells': '0.201', 'Keratinocyte (other)': '-0.023', 'Keratinocyte (granular)': '-0.127', 'Hair cortex cells': '-0.037', 'Inner root sheath cells': '0.019', 'Outer root sheath cells': '0.139', 'Sebaceous gland cells': '0.016', 'Eccrine sweat gland cells': '0.074', 'Adipocytes (Skin)': '0.028', 'Mitotic cells (Skin)': '0.156', 'Parietal cells': '-0.577', 'Chief cells': '-0.512', 'Gastric mucous cells': '-0.217', 'Gastric enteroendocrine cells': '-0.378', 'Mitotic cells (Stomach)': '0.185', 'Parafollicular cells': '0.042', 'Thyroid glandular cells': '0.275', 'Mitotic cells (Thyroid)': '0.059', 'Adrenal cortex cells': '0.656', 'Adrenal medulla cells': '0.065', 'Mitotic cells (Adrenal gland)': '0.476', 'Minor salivary glandular cells': '0.612', 'Minor salivary gland ductal cells': '0.021', 'Minor salivary gland basal cells': '0.402', 'Mitotic cells (Minor salivary gland)': '0.466', 'Adipocytes (Minor salivary gland)': '0.128', 'Somatotropes': '0.282', 'Lactotropes': '0.122', 'Gonadotropes': '-0.010', 'Corticotropes': '-0.165', 'Thyrotropes': '0.042', 'Undifferentiated cells (Pituitary gland)': '-0.088', 'Mitotic cells (Spleen)': '-0.131', 'Platelets': '-0.080', 'Erythrocytes': '-0.085', 'Hematopoietic stem cells': '-0.214', 'B-cells (Spleen)': '0.294', 'NK-cells (Spleen)': '0.290', 'Amygdala excitatory': '63.7', 'Cerebellar inhibitory': '64.5', 'Cge interneuron': '54.9', 'Deep-layer corticothalamic and 6b': '68.3', 'Deep-layer intratelencephalic': '66.3', 'Deep-layer near-projecting': '102.4', 'Eccentric medium spiny neuron': '64.9', 'Hippocampal ca1-3': '61.3', 'Hippocampal ca4': '68.9', 'Hippocampal dentate gyrus': '58.2', 'Lamp5-lhx6 and chandelier': '60.1', 'Lower rhombic lip': '85.9', 'Mammillary body': '67.6', 'Medium spiny neuron': '57.0', 'Mge interneuron': '65.7', 'Midbrain-derived inhibitory': '66.3', 'Miscellaneous': '56.3', 'Splatter': '67.4', 'Thalamic excitatory': '126.4', 'Upper rhombic lip': '63.5', 'Upper-layer intratelencephalic': '71.3', 'Astrocyte': '55.5', 'Bergmann glia': '56.0', 'Central nervous system macrophage': '114.1', 'Choroid plexus epithelial cell': '65.5', 'Committed oligodendrocyte precursor': '54.0', 'Ependymal cell': '37.9', 'Oligodendrocyte': '78.4', 'Oligodendrocyte precursor cell': '57.9', 'Endothelial cell': '102.5', 'Pericyte': '62.5', 'Vascular associated smooth muscle cell': '60.8', 'Fibroblast': '84.0', 'Leukocyte': '80.3', 'Basophil': '57.1', 'Eosinophil': '24.5', 'Neutrophil': '57.6', 'Classical monocyte': '36.6', 'Non-classical monocyte': '60.6', 'Intermediate monocyte': '46.0', 'T-reg': '23.6', 'GdT-cell': '14.0', 'MAIT T-cell': '25.0', 'Memory CD4 T-cell': '10.2', 'Naive CD4 T-cell': '11.8', 'Memory CD8 T-cell': '15.2', 'Naive CD8 T-cell': '12.9', 'Memory B-cell': '12.9', 'Naive B-cell': '35.2', 'Plasmacytoid DC': '11.7', 'Myeloid DC': '36.5', 'NK-cell': '66.8', 'Total PBMC': '28.1', 'Vd2 gdTCR': '47.3', 'Memory CD4 T-cell TFH': '26.7', 'Memory CD4 T-cell Th2': '37.5', 'Memory CD4 T-cell Th17': '35.6', 'Memory CD4 T-cell Th1\\/Th17': '47.7', 'Non-Vd2 gdTCR': '50.0', 'Memory CD4 T-cell Th1': '35.7', 'Terminal effector memory CD4 T-cell': '44.5', 'Central memory CD8 T-cell': '19.5', 'Effector memory CD8 T-cell': '44.2', 'Terminal effector memory CD8 T-cell': '46.4', 'Switched memory B-cell': '28.9', 'Plasmablast': '37.0', 'Non-switched memory B-cell': '20.5', 'Exhausted memory B-cell': '21.3', 'Progenitor cell': '9.8', 'Naive CD4 T-cell activated': '5.5', 'Naive CD8 T-cell activated': '6.9', 'Memory T-reg': '40.9', 'Naive T-reg': '20.4'}
4EFO, 4EUT, 4EUU, 4IM0, 4IM2, 4IM3, 4IW0, 4IWO, 4IWP, 4IWQ, 5EOA, 5EOF, 5EP6, 5W5V, 6BNY, 6BOD, 6BOE, 6CQ0, 6CQ4, 6CQ5, 6NT9, 6O8B, 6RSR, 6RST, 6RSU
{'Adipose Tissue': 25.14706063122924, 'Adrenal Gland': 27.124589147286823, 'Bladder': 25.653333333333336, 'Blood': 17.975826695371367, 'Blood Vessel': 26.485053932584268, 'Brain': 13.811599545798638, 'Breast': 25.65735947712418, 'Cervix Uteri': 28.643684210526317, 'Colon': 21.12450706033376, 'Esophagus': 21.544210380622836, 'Fallopian Tube': 27.333333333333332, 'Heart': 8.100483507549361, 'Kidney': 11.153629213483146, 'Liver': 11.378650442477875, 'Lung': 33.63641868512111, 'Muscle': 18.001170610211705, 'Nerve': 27.994442649434575, 'Ovary': 25.219444444444445, 'Pancreas': 6.630317073170732, 'Pituitary': 23.795088339222616, 'Prostate': 24.6145306122449, 'Salivary Gland': 20.22978395061728, 'Skin': 23.38969485903814, 'Small Intestine': 23.96101604278075, 'Spleen': 29.430497925311204, 'Stomach': 17.541384401114207, 'Testis': 44.16016620498615, 'Thyroid': 24.114961715160796, 'Uterus': 30.87718309859155, 'Vagina': 26.03076923076923}
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[0.66, 0.32, 0.25, 0.02, 0.79, 0.4, 0.05, 0.38, 0.01, 0.47, 0.47, 0.8, 0.25, 0.46, 0.47, 0.35, 0.83, 0.52, 0.74, 0.31, 0.07, 0.23, 0.22, 0.07, 0.4, 0.03, 0.52, 0.21, 0.46, 0.87, 0.58, 0.4, 0.5, 0.4, 0.14, 0.06, 0.0, 0.04, 0.14, 0.09, 0.22, 0.68, 0.64, 0.04, 0.34, 0.79, 0.24, 0.62, 0.6, 0.78, 0.21, 0.18, 0.39, 0.32, 0.06, 0.05, 0.45, 0.01, 0.05, 0.75, 0.49, 0.1, 0.77, 0.35, 0.69, 0.01, 0.03, 0.04, 0.5, 0.2, 0.5, 0.33, 0.47, 0.11, 0.35, 0.03, 0.59, 0.85, 0.51, 0.66, 0.24, 0.4, 0.0, 0.0, 0.0, 0.08, 0.23, 0.21, 0.08, 0.65, 0.31, 0.24, 0.11, 0.0, 0.5, 0.48, 0.09, 0.06, 0.26, 0.38, 0.05, 0.59, 0.07, 0.25, 0.23, 0.09, 0.01, 0.56, 0.08, 0.64, 0.19, 0.0, 0.24, 0.1, 0.0, 0.01, 0.43, 0.04, 0.02, 0.08, 0.25, 0.0, 0.02, 0.33, 0.15, 0.0, 0.26, 0.7, 0.34, 0.27, 0.04, 0.06, 0.01, 0.03, 0.12, 0.02, 0.2, 0.01, 0.39, 0.09, 0.0, 0.2, 0.24, 0.14, 0.53, 0.31, 0.99, 0.71, 0.63, 0.47, 0.04, 0.25, 0.01, 0.11, 0.02, 0.13, 0.36, 0.02, 0.25, 0.06, 0.0, 0.28, 0.44, 0.07, 0.81, 0.6, 0.91, 0.36, 0.51, 0.0, 0.51, 0.34, 0.41, 0.29, 0.52, 0.23, 0.27, 0.14, 0.09, 0.06, 0.05, 0.01, 0.12, 0.03, 0.01, 0.1, 0.2, 0.41, 0.2, 0.19, 0.84, 0.35, 0.86, 0.42, 0.9, 0.52, 0.54, 0.01, 0.17, 0.15, 0.25, 0.03, 0.0, 0.0, 0.01, 0.07, 0.01, 0.0, 0.0, 0.01, 0.0, 0.05, 0.14, 0.0, 0.0, 0.03, 0.23, 0.34, 0.22, 0.01, 0.03, 0.41, 0.05, 0.35, 0.62, 0.26, 0.17, 0.65, 0.75, 0.31, 0.31, 0.51, 0.25, 0.03, 0.17, 0.66, 0.0, 0.01, 0.46, 0.59, 0.09, 0.51, 0.61, 0.44, 0.06, 0.0, 0.06, 0.0, 0.19, 0.11, 0.69, 0.53, 0.76, 0.86, 0.32, 0.74, 0.3, 0.38, 0.34, 0.31, 0.35, 0.48, 0.1, 0.38, 0.51, 0.09, 0.09, 0.25, 0.04, 0.17, 0.5, 0.11, 0.0, 0.1, 0.55, 0.24, 0.03, 0.18, 0.44, 0.03, 0.0, 0.13, 0.28, 0.0, 0.0, 0.07, 0.26, 0.38, 0.42, 0.91, 0.57, 0.17, 0.18, 0.5, 0.1, 0.62, 0.46, 0.0, 0.11, 0.54, 0.36, 0.01, 0.31, 0.32, 0.04, 0.31, 0.67, 0.23, 0.38, 0.34, 0.04, 0.15, 0.02, 0.0, 0.01, 0.03, 0.01, 0.08, 0.0, 0.13, 0.47, 0.12, 0.17, 0.01, 0.06, 0.0, 0.08, 0.32, 0.71, 0.13, 0.28, 0.0, 0.45, 0.35, 0.0, 0.16, 0.46, 0.18, 0.01, 0.45, 0.65, 0.27, 0.03, 0.64, 0.03, 0.51, 0.41, 0.87, 0.29, 0.08, 0.21, 0.06, 0.02, 0.18, 0.67, 0.27, 0.58, 0.42, 0.2, 0.74, 0.1, 0.68, 0.56, 0.68, 0.41, 0.33, 0.02, 0.6, 0.63, 0.11, 0.21, 0.88, 0.18, 0.48, 0.42, 0.62, 0.21, 0.03, 0.0, 0.0, 0.0, 0.0, 0.03, 0.4, 0.61, 0.85, 0.26, 0.8, 0.2, 0.5, 0.04, 0.18, 0.72, 0.21, 0.42, 0.8, 0.2, 0.84, 0.26, 0.38, 0.94, 0.31, 0.67, 0.88, 0.74, 0.31, 0.45, 0.11, 0.42, 0.35, 0.03, 0.09, 0.6, 0.14, 0.0, 0.24, 0.43, 0.0, 0.0, 0.01, 0.04, 0.01, 0.13, 0.05, 0.03, 0.07, 0.38, 0.06, 0.05, 0.45, 0.24, 0.01, 0.19, 0.26, 0.09, 0.0, 0.35, 0.04, 0.01, 0.06, 0.2, 0.01, 0.01, 0.49, 0.15, 0.02, 0.08, 0.49, 0.03, 0.01, 0.3, 0.56, 0.19, 0.14, 0.49, 0.68, 0.04, 0.27, 0.7, 0.23, 0.11, 0.47, 0.51, 0.09, 0.23, 0.64, 0.32, 0.02, 0.35, 0.53, 0.02, 0.09, 0.59, 0.1, 0.04, 0.37, 0.63, 0.06, 0.25, 0.67, 0.41, 0.04, 0.52, 0.75, 0.22, 0.26, 0.85, 0.73, 0.94, 0.42, 0.8, 0.72, 0.71, 0.39, 0.32, 0.37, 0.52, 0.04, 0.5, 0.6, 0.11, 0.23, 0.45, 0.49, 0.0, 0.45, 0.67, 0.09, 0.34, 0.6, 0.42, 0.21, 0.41, 0.57, 0.01, 0.34, 0.62, 0.36, 0.02, 0.56, 0.47, 0.01, 0.41, 0.51, 0.18, 0.08, 0.4, 0.84, 0.96, 0.2, 0.51, 0.03, 0.21, 0.29, 0.48, 0.15, 0.05, 0.57, 0.79, 0.31, 0.11, 0.06, 0.15, 0.48, 0.8, 0.28, 0.59, 0.07, 0.24, 0.45, 0.47, 0.01, 0.39, 0.6, 0.13, 0.07, 0.47, 0.35, 0.0, 0.26, 0.69, 0.1, 0.05, 0.46, 0.45, 0.0, 0.46, 0.6, 0.07, 0.4, 0.71, 0.63, 0.74, 0.9, 0.13, 0.58, 0.75, 0.71, 0.53, 0.3, 0.35, 0.56, 0.02, 0.35, 0.59, 0.19, 0.09, 0.65, 0.48, 0.0, 0.46, 0.63, 0.2, 0.0, 0.38, 0.51, 0.01, 0.15, 0.45, 0.27, 0.06, 0.53, 0.63, 0.27, 0.05, 0.1, 0.66, 0.34, 0.03, 0.46, 0.3, 0.0, 0.17, 0.62, 0.4, 0.01, 0.45, 0.36, 0.05, 0.06, 0.58, 0.4, 0.01, 0.15, 0.55, 0.01, 0.04, 0.76, 0.36, 0.03, 0.41, 0.46, 0.09, 0.22, 0.48, 0.37, 0.02, 0.47, 0.57, 0.1, 0.29, 0.72, 0.44, 0.02, 0.47, 0.74, 0.13, 0.32, 0.62, 0.28, 0.03, 0.4, 0.53, 0.12, 0.4, 0.74, 0.39, 0.14, 0.52, 0.68, 0.37, 0.42, 0.8, 0.68, 0.59, 0.59, 0.83, 0.95, 0.76, 0.99, 0.79, 0.98, 0.89, 0.88, 0.71, 0.89, 0.82, 0.92, 0.52, 0.65, 0.64, 0.49, 0.72, 0.54, 0.66, 0.6, 0.59, 0.63, 0.46, 0.67, 0.66, 0.6, 0.53, 0.6, 0.6, 0.52, 0.61, 0.56, 0.39, 0.53, 0.64, 0.63, 0.61, 0.55, 0.56, 0.54, 0.51, 0.45, 0.58, 0.49, 0.64, 0.45, 0.68, 0.59, 0.36, 0.64, 0.73, 0.66, 0.89, 0.83, 0.74, 0.7, 0.88, 0.91, 0.82, 0.86, 0.9, 0.94, 0.98]
RING finger
Part of a complex consisting of TRIM27, USP7 and MAGEL2
null
null
EID1, MAGED4, MAGEF1, SQSTM1, EPC1, CHD4, MAGEL2, PML, EIF3S6, PTPN11, USP7,
PIK3C2B, WASHC1, TBK1, NOD2,ULK1, STK38L
48, 63
null
null
Homomultimerizes
null
88.603957
0.43115
89.656872
0.338313
950
P14373
Q9Y6X2
31747314
UbiBrowser
TRIM27
MASGSVAECLQQETTCPVCLQYFAEPMMLDCGHNICCACLARCWGTAETNVSCPQCRETFPQRHMRPNRHLANVTQLVKQLRTERPSGPGGEMGVCEKHREPLKLYCEEDQMPICVVCDRSREHRGHSVLPLEEAVEGFKEQIQNQLDHLKRVKDLKKRRRAQGEQARAELLSLTQMEREKIVWEFEQLYHSLKEHEYRLLARLEELDLAIYNSINGAITQFSCNISHLSSLIAQLEEKQQQPTRELLQDIGDTLSRAERIRIPEPWITPPDLQEKIHIFAQKCLFLTESLKQFTEKMQSDMEKIQELREAQLYSVDVTLDPDTAYPSLILSDNLRQVRYSYLQQDLPDNPERFNLFPCVLGSPCFIAGRHYWEVEVGDKAKWTIGVCEDSVCRKGGVTSAPQNGFWAVSLWYGKEYWALTSPMTALPLRTPLQRVGIFLDYDAGEVSFYNVTERCHTFTFSHATFCGPVRPYFSLSYSGGKSAAPLIICPMSGIDGFSGHVGNHGHSMETSP
Homo sapiens
Nucleus, Cytoplasm, Nucleus, PML body, Early endosome, Mitochondrion
Low tissue specificity
{'Ciliated cells': '25.1', 'Basal respiratory cells': '27.3', 'Club cells': '24.7', 'Ionocytes': '23.2', 'Mucus glandular cells': '21.7', 'Serous glandular cells': '33.5', 'Gastric mucus-secreting cells': '23.6', 'Proximal enterocytes': '20.1', 'Paneth cells': '20.0', 'Distal enterocytes': '15.1', 'Intestinal goblet cells': '37.0', 'Exocrine glandular cells': '-0.693', 'Basal prostatic cells': '43.6', 'Prostatic glandular cells': '43.5', 'Breast glandular cells': '0.696', 'Breast myoepithelial cells': '0.544', 'Glandular and luminal cells': '29.8', 'Secretory cells': '37.3', 'Basal keratinocytes': '26.5', 'Suprabasal keratinocytes': '15.7', 'Basal squamous epithelial cells': '34.1', 'Squamous epithelial cells': '21.9', 'Alveolar cells type 1': '-0.038', 'Alveolar cells type 2': '-0.408', 'Salivary duct cells': '18.1', 'Ductal cells': '0.480', 'Hepatocytes': '0.177', 'Cholangiocytes': '22.9', 'Proximal tubular cells': '0.232', 'Distal tubular cells': '18.4', 'Collecting duct cells': '27.2', 'Mesothelial cells': '0.392', 'Sertoli cells': '0.703', 'Granulosa cells': '19.2', 'Enteroendocrine cells': '31.0', 'Pancreatic endocrine cells': '18.7', 'Leydig cells': '0.636', 'Excitatory neurons': '13.0', 'Inhibitory neurons': '12.8', 'Cone photoreceptor cells': '13.6', 'Rod photoreceptor cells': '11.3', 'Bipolar cells': '10.1', 'Horizontal cells': '7.6', 'Astrocytes': '11.1', 'Oligodendrocyte precursor cells': '17.9', 'Oligodendrocytes': '18.4', 'Microglial cells': '16.1', 'Muller glia cells': '12.1', 'Schwann cells': '0.026', 'Spermatogonia': '0.420', 'Spermatocytes': '-0.042', 'Early spermatids': '-0.589', 'Late spermatids': '-0.706', 'Oocytes': '13.2', 'Cytotrophoblasts': '48.8', 'Syncytiotrophoblasts': '50.5', 'Extravillous trophoblasts': '58.8', 'Endothelial cells': '27.6', 'Lymphatic endothelial cells': '18.3', 'Cardiomyocytes': '0.444', 'Skeletal myocytes': '-0.371', 'Smooth muscle cells': '19.7', 'Adipocytes': '20.7', 'Melanocytes': '-0.177', 'Fibroblasts': '22.4', 'Peritubular cells': '0.559', 'Endometrial stromal cells': '27.3', 'Ovarian stromal cells': '24.5', 'Undifferentiated cells': '29.3', 'T-cells': '28.5', 'B-cells': '33.6', 'Plasma cells': '50.4', 'Nk-cells': '25.7', 'Granulocytes': '27.4', 'Monocytes': '32.5', 'Macrophages': '29.6', 'Hofbauer cells': '38.9', 'Kupffer cells': '31.1', 'Dendritic cells': '32.8', 'Langerhans cells': '0.075', 'Erythroid cells': '-0.057', 'Adipocytes (Subcutaneous)': '-0.199', 'Adipocytes (Visceral)': '-0.372', 'Breast glandular cells (progenitors)': '0.493', 'Adipocytes (Breast)': '-0.659', 'Colon enterocytes': '-0.039', 'Colon enteroendocrine cells': '0.155', 'Enteric glia cells': '0.411', 'Mitotic cells (Colon)': '0.069', 'Mitotic cells (Heart)': '0.481', 'Podocytes': '-0.080', 'Ascending Loop of Henle cells': '0.332', 'Intercalated cells': '-0.067', 'Cholangiocyte': '0.283', 'NK-cells (Liver)': '-0.293', 'Respiratory ciliated cells': '0.036', 'Mitotic cells (Lung)': '-0.109', 'NK-cells (Lung)': '0.295', 'B-cells (Lung)': '0.112', 'Alpha cells': '0.335', 'Beta cells': '0.170', 'Prostate glandular cells': '0.251', 'Prostate basal glandular cells': '0.383', 'Urothelial cells': '0.310', 'Keratinocyte (other)': '-0.109', 'Keratinocyte (granular)': '-0.354', 'Hair cortex cells': '0.029', 'Inner root sheath cells': '0.037', 'Outer root sheath cells': '0.284', 'Sebaceous gland cells': '0.136', 'Eccrine sweat gland cells': '0.208', 'Adipocytes (Skin)': '0.020', 'Mitotic cells (Skin)': '0.110', 'Parietal cells': '-0.236', 'Chief cells': '-0.025', 'Gastric mucous cells': '0.098', 'Gastric enteroendocrine cells': '0.091', 'Mitotic cells (Stomach)': '0.263', 'Parafollicular cells': '0.070', 'Thyroid glandular cells': '0.072', 'Mitotic cells (Thyroid)': '0.055', 'Adrenal cortex cells': '0.312', 'Adrenal medulla cells': '-0.104', 'Mitotic cells (Adrenal gland)': '-0.086', 'Minor salivary glandular cells': '0.517', 'Minor salivary gland ductal cells': '0.287', 'Minor salivary gland basal cells': '-0.017', 'Mitotic cells (Minor salivary gland)': '0.010', 'Adipocytes (Minor salivary gland)': '0.057', 'Somatotropes': '0.482', 'Lactotropes': '0.227', 'Gonadotropes': '0.066', 'Corticotropes': '0.019', 'Thyrotropes': '0.026', 'Undifferentiated cells (Pituitary gland)': '-0.250', 'Mitotic cells (Spleen)': '-0.238', 'Platelets': '-0.171', 'Erythrocytes': '-0.096', 'Hematopoietic stem cells': '-0.313', 'B-cells (Spleen)': '0.377', 'NK-cells (Spleen)': '0.278', 'Amygdala excitatory': '29.4', 'Cerebellar inhibitory': '15.3', 'Cge interneuron': '27.6', 'Deep-layer corticothalamic and 6b': '29.3', 'Deep-layer intratelencephalic': '31.8', 'Deep-layer near-projecting': '34.8', 'Eccentric medium spiny neuron': '27.3', 'Hippocampal ca1-3': '26.5', 'Hippocampal ca4': '28.4', 'Hippocampal dentate gyrus': '29.8', 'Lamp5-lhx6 and chandelier': '22.8', 'Lower rhombic lip': '32.2', 'Mammillary body': '18.8', 'Medium spiny neuron': '22.8', 'Mge interneuron': '26.6', 'Midbrain-derived inhibitory': '28.4', 'Miscellaneous': '30.0', 'Splatter': '27.8', 'Thalamic excitatory': '23.9', 'Upper rhombic lip': '24.1', 'Upper-layer intratelencephalic': '28.8', 'Astrocyte': '26.3', 'Bergmann glia': '25.2', 'Central nervous system macrophage': '78.3', 'Choroid plexus epithelial cell': '42.9', 'Committed oligodendrocyte precursor': '33.8', 'Ependymal cell': '20.3', 'Oligodendrocyte': '36.0', 'Oligodendrocyte precursor cell': '32.2', 'Endothelial cell': '58.5', 'Pericyte': '33.4', 'Vascular associated smooth muscle cell': '31.7', 'Fibroblast': '43.5', 'Leukocyte': '58.3', 'Basophil': '20.3', 'Eosinophil': '2.5', 'Neutrophil': '51.3', 'Classical monocyte': '17.4', 'Non-classical monocyte': '33.2', 'Intermediate monocyte': '36.3', 'T-reg': '19.6', 'GdT-cell': '7.2', 'MAIT T-cell': '29.7', 'Memory CD4 T-cell': '10.6', 'Naive CD4 T-cell': '29.7', 'Memory CD8 T-cell': '5.6', 'Naive CD8 T-cell': '28.3', 'Memory B-cell': '7.1', 'Naive B-cell': '18.7', 'Plasmacytoid DC': '27.3', 'Myeloid DC': '30.5', 'NK-cell': '26.2', 'Total PBMC': '23.0', 'Vd2 gdTCR': '19.2', 'Memory CD4 T-cell Th1\\/Th17': '22.6', 'Memory CD4 T-cell Th17': '23.3', 'Memory CD4 T-cell Th2': '23.3', 'Non-Vd2 gdTCR': '18.3', 'Memory CD4 T-cell Th1': '23.8', 'Memory CD4 T-cell TFH': '24.9', 'Terminal effector memory CD4 T-cell': '26.8', 'Central memory CD8 T-cell': '23.4', 'Effector memory CD8 T-cell': '21.7', 'Terminal effector memory CD8 T-cell': '14.3', 'Non-switched memory B-cell': '22.5', 'Plasmablast': '44.1', 'Switched memory B-cell': '25.7', 'Exhausted memory B-cell': '13.9', 'Progenitor cell': '20.6', 'Memory T-reg': '26.0', 'Naive CD4 T-cell activated': '55.5', 'Naive CD8 T-cell activated': '61.3', 'Naive T-reg': '32.5'}
null
{'Adipose Tissue': 30.51002491694352, 'Adrenal Gland': 28.42209302325581, 'Bladder': 42.15761904761904, 'Blood': 47.71387405812702, 'Blood Vessel': 35.17883895131086, 'Brain': 17.082769114307343, 'Breast': 35.04257080610022, 'Cervix Uteri': 56.090526315789475, 'Colon': 26.715078305519896, 'Esophagus': 25.588709342560552, 'Fallopian Tube': 54.83888888888889, 'Heart': 12.228174216027876, 'Kidney': 20.893404494382025, 'Liver': 28.784889380530977, 'Lung': 43.63569204152249, 'Muscle': 13.141891656288918, 'Nerve': 43.2170436187399, 'Ovary': 50.49094444444445, 'Pancreas': 26.43318292682927, 'Pituitary': 49.52038869257951, 'Prostate': 47.70363265306122, 'Salivary Gland': 32.1683950617284, 'Skin': 30.310514648977335, 'Small Intestine': 34.5279679144385, 'Spleen': 56.557759336099586, 'Stomach': 26.06833704735376, 'Testis': 26.19157894736842, 'Thyroid': 45.41816232771823, 'Uterus': 52.2319014084507, 'Vagina': 36.81769230769231}
PIAS3
MAELGELKHMVMSFRVSELQVLLGFAGRNKSGRKHELLAKALHLLKSSCAPSVQMKIKELYRRRFPRKTLGPSDLSLLSLPPGTSPVGSPGPLAPIPPTLLAPGTLLGPKREVDMHPPLPQPVHPDVTMKPLPFYEVYGELIRPTTLASTSSQRFEEAHFTFALTPQQVQQILTSREVLPGAKCDYTIQVQLRFCLCETSCPQEDYFPPNLFVKVNGKLCPLPGYLPPTKNGAEPKRPSRPINITPLARLSATVPNTIVVNWSSEFGRNYSLSVYLVRQLTAGTLLQKLRAKGIRNPDHSRALIKEKLTADPDSEVATTSLRVSLMCPLGKMRLTVPCRALTCAHLQSFDAALYLQMNEKKPTWTCPVCDKKAPYESLIIDGLFMEILSSCSDCDEIQFMEDGSWCPMKPKKEASEVCPPPGYGLDGLQYSPVQGGDPSENKKKVEVIDLTIESSSDEEDLPPTKKHCSVTSAAIPALPGSKGVLTSGHQPSSVLRSPAMGTLGGDFLSSLPLHEYPPAFPLGADIQGLDLFSFLQTESQHYGPSVITSLDEQDALGHFFQYRGTPSHFLGPLAPTLGSSHCSATPAPPPGRVSSIVAPGGALREGHGGPLPSGPSLTGCRSDIISLD
Homo sapiens
Cytoplasm, Nucleus, Nucleus speckle
Low tissue specificity
{'Ciliated cells': '28.2', 'Basal respiratory cells': '14.3', 'Club cells': '17.6', 'Ionocytes': '24.3', 'Mucus glandular cells': '6.5', 'Serous glandular cells': '10.8', 'Gastric mucus-secreting cells': '12.4', 'Proximal enterocytes': '1.6', 'Paneth cells': '2.0', 'Distal enterocytes': '1.8', 'Intestinal goblet cells': '6.4', 'Exocrine glandular cells': '-0.569', 'Basal prostatic cells': '17.7', 'Prostatic glandular cells': '10.1', 'Breast glandular cells': '0.705', 'Breast myoepithelial cells': '0.575', 'Glandular and luminal cells': '19.2', 'Secretory cells': '8.2', 'Basal keratinocytes': '12.2', 'Suprabasal keratinocytes': '19.5', 'Basal squamous epithelial cells': '15.5', 'Squamous epithelial cells': '20.7', 'Alveolar cells type 1': '-0.116', 'Alveolar cells type 2': '-0.181', 'Salivary duct cells': '10.9', 'Ductal cells': '0.521', 'Hepatocytes': '0.301', 'Cholangiocytes': '3.8', 'Proximal tubular cells': '0.033', 'Distal tubular cells': '6.1', 'Collecting duct cells': '13.6', 'Mesothelial cells': '0.352', 'Sertoli cells': '0.510', 'Granulosa cells': '7.5', 'Enteroendocrine cells': '3.6', 'Pancreatic endocrine cells': '10.2', 'Leydig cells': '0.629', 'Excitatory neurons': '4.1', 'Inhibitory neurons': '3.8', 'Cone photoreceptor cells': '8.5', 'Rod photoreceptor cells': '12.9', 'Bipolar cells': '9.5', 'Horizontal cells': '7.6', 'Astrocytes': '8.1', 'Oligodendrocyte precursor cells': '6.1', 'Oligodendrocytes': '6.9', 'Microglial cells': '7.2', 'Muller glia cells': '5.3', 'Schwann cells': '0.265', 'Spermatogonia': '0.561', 'Spermatocytes': '0.141', 'Early spermatids': '-0.484', 'Late spermatids': '-0.673', 'Oocytes': '8.8', 'Cytotrophoblasts': '3.6', 'Syncytiotrophoblasts': '3.8', 'Extravillous trophoblasts': '7.9', 'Endothelial cells': '13.3', 'Lymphatic endothelial cells': '21.4', 'Cardiomyocytes': '0.470', 'Skeletal myocytes': '-0.310', 'Smooth muscle cells': '14.3', 'Adipocytes': '15.4', 'Melanocytes': '0.148', 'Fibroblasts': '12.2', 'Peritubular cells': '0.636', 'Endometrial stromal cells': '14.5', 'Ovarian stromal cells': '11.5', 'Undifferentiated cells': '3.8', 'T-cells': '8.0', 'B-cells': '9.4', 'Plasma cells': '6.5', 'Nk-cells': '8.4', 'Granulocytes': '3.0', 'Monocytes': '6.5', 'Macrophages': '5.1', 'Hofbauer cells': '4.9', 'Kupffer cells': '5.3', 'Dendritic cells': '10.7', 'Langerhans cells': '0.310', 'Erythroid cells': '-0.011', 'Adipocytes (Subcutaneous)': '-0.494', 'Adipocytes (Visceral)': '-0.384', 'Breast glandular cells (progenitors)': '0.512', 'Adipocytes (Breast)': '-0.547', 'Colon enterocytes': '-0.173', 'Colon enteroendocrine cells': '0.261', 'Enteric glia cells': '0.376', 'Mitotic cells (Colon)': '-0.152', 'Mitotic cells (Heart)': '0.544', 'Podocytes': '-0.107', 'Ascending Loop of Henle cells': '0.445', 'Intercalated cells': '-0.071', 'Cholangiocyte': '0.386', 'NK-cells (Liver)': '-0.243', 'Respiratory ciliated cells': '0.303', 'Mitotic cells (Lung)': '0.072', 'NK-cells (Lung)': '0.070', 'B-cells (Lung)': '-0.014', 'Alpha cells': '0.468', 'Beta cells': '0.329', 'Prostate glandular cells': '-0.280', 'Prostate basal glandular cells': '0.290', 'Urothelial cells': '0.328', 'Keratinocyte (other)': '0.429', 'Keratinocyte (granular)': '-0.010', 'Hair cortex cells': '-0.153', 'Inner root sheath cells': '-0.099', 'Outer root sheath cells': '0.098', 'Sebaceous gland cells': '-0.052', 'Eccrine sweat gland cells': '-0.180', 'Adipocytes (Skin)': '-0.287', 'Mitotic cells (Skin)': '0.300', 'Parietal cells': '-0.590', 'Chief cells': '-0.506', 'Gastric mucous cells': '-0.327', 'Gastric enteroendocrine cells': '-0.333', 'Mitotic cells (Stomach)': '0.028', 'Parafollicular cells': '0.000', 'Thyroid glandular cells': '0.058', 'Mitotic cells (Thyroid)': '0.017', 'Adrenal cortex cells': '0.268', 'Adrenal medulla cells': '0.141', 'Mitotic cells (Adrenal gland)': '0.265', 'Minor salivary glandular cells': '0.109', 'Minor salivary gland ductal cells': '0.389', 'Minor salivary gland basal cells': '0.308', 'Mitotic cells (Minor salivary gland)': '0.079', 'Adipocytes (Minor salivary gland)': '0.104', 'Somatotropes': '0.122', 'Lactotropes': '-0.190', 'Gonadotropes': '-0.109', 'Corticotropes': '-0.259', 'Thyrotropes': '-0.083', 'Undifferentiated cells (Pituitary gland)': '0.264', 'Mitotic cells (Spleen)': '-0.355', 'Platelets': '-0.143', 'Erythrocytes': '-0.114', 'Hematopoietic stem cells': '-0.370', 'B-cells (Spleen)': '0.255', 'NK-cells (Spleen)': '0.239', 'Amygdala excitatory': '9.4', 'Cerebellar inhibitory': '6.4', 'Cge interneuron': '9.0', 'Deep-layer corticothalamic and 6b': '6.8', 'Deep-layer intratelencephalic': '7.9', 'Deep-layer near-projecting': '7.7', 'Eccentric medium spiny neuron': '8.1', 'Hippocampal ca1-3': '6.4', 'Hippocampal ca4': '6.8', 'Hippocampal dentate gyrus': '9.2', 'Lamp5-lhx6 and chandelier': '8.0', 'Lower rhombic lip': '5.9', 'Mammillary body': '6.6', 'Medium spiny neuron': '5.7', 'Mge interneuron': '7.9', 'Midbrain-derived inhibitory': '12.6', 'Miscellaneous': '8.1', 'Splatter': '9.6', 'Thalamic excitatory': '7.5', 'Upper rhombic lip': '11.0', 'Upper-layer intratelencephalic': '9.1', 'Astrocyte': '18.6', 'Bergmann glia': '16.5', 'Central nervous system macrophage': '12.5', 'Choroid plexus epithelial cell': '13.0', 'Committed oligodendrocyte precursor': '11.1', 'Ependymal cell': '25.7', 'Oligodendrocyte': '9.9', 'Oligodendrocyte precursor cell': '12.1', 'Endothelial cell': '24.2', 'Pericyte': '26.0', 'Vascular associated smooth muscle cell': '20.2', 'Fibroblast': '24.3', 'Leukocyte': '10.8', 'Basophil': '38.2', 'Eosinophil': '10.7', 'Neutrophil': '8.1', 'Classical monocyte': '18.2', 'Non-classical monocyte': '25.6', 'Intermediate monocyte': '29.0', 'T-reg': '25.7', 'GdT-cell': '10.6', 'MAIT T-cell': '25.6', 'Memory CD4 T-cell': '6.8', 'Naive CD4 T-cell': '21.6', 'Memory CD8 T-cell': '11.6', 'Naive CD8 T-cell': '23.0', 'Memory B-cell': '5.4', 'Naive B-cell': '20.9', 'Plasmacytoid DC': '67.2', 'Myeloid DC': '24.2', 'NK-cell': '42.7', 'Total PBMC': '24.8', 'Vd2 gdTCR': '35.1', 'Memory CD4 T-cell Th1\\/Th17': '23.3', 'Memory CD4 T-cell Th17': '26.0', 'Memory CD4 T-cell Th2': '27.0', 'Non-Vd2 gdTCR': '29.6', 'Memory CD4 T-cell Th1': '28.6', 'Memory CD4 T-cell TFH': '31.3', 'Terminal effector memory CD4 T-cell': '42.7', 'Central memory CD8 T-cell': '30.8', 'Effector memory CD8 T-cell': '34.2', 'Terminal effector memory CD8 T-cell': '36.3', 'Non-switched memory B-cell': '20.4', 'Plasmablast': '37.0', 'Switched memory B-cell': '28.3', 'Exhausted memory B-cell': '28.6', 'Progenitor cell': '30.7', 'Memory T-reg': '30.8', 'Naive CD4 T-cell activated': '5.3', 'Naive CD8 T-cell activated': '7.9', 'Naive T-reg': '23.8'}
4MVT
{'Adipose Tissue': 39.9765, 'Adrenal Gland': 19.715798449612404, 'Bladder': 68.97619047619048, 'Blood': 10.1171654467169, 'Blood Vessel': 80.2234456928839, 'Brain': 19.63740193035579, 'Breast': 58.6722440087146, 'Cervix Uteri': 101.3384210526316, 'Colon': 43.000510911424904, 'Esophagus': 54.36515570934256, 'Fallopian Tube': 94.2811111111111, 'Heart': 15.160500580720091, 'Kidney': 21.265, 'Liver': 6.816367256637168, 'Lung': 48.6530276816609, 'Muscle': 20.09502739726027, 'Nerve': 76.33308562197092, 'Ovary': 71.22033333333333, 'Pancreas': 12.959326219512194, 'Pituitary': 42.5756183745583, 'Prostate': 59.84991836734694, 'Salivary Gland': 55.28296296296296, 'Skin': 65.84705362078496, 'Small Intestine': 33.25490374331551, 'Spleen': 32.84647302904564, 'Stomach': 37.7016295264624, 'Testis': 31.93764542936288, 'Thyroid': 44.45900306278713, 'Uterus': 95.54683098591548, 'Vagina': 85.54775641025641}
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[0.89, 0.79, 0.48, 0.51, 0.54, 0.54, 0.03, 0.5, 0.63, 0.09, 0.0, 0.54, 0.21, 0.0, 0.61, 0.36, 0.56, 0.07, 0.0, 0.37, 0.48, 0.0, 0.0, 0.33, 0.48, 0.29, 0.79, 0.33, 0.58, 0.51, 0.53, 0.51, 0.69, 0.47, 0.7, 0.43, 0.0, 0.23, 0.49, 0.3, 0.0, 0.23, 0.55, 0.07, 0.07, 0.84, 0.52, 0.69, 0.23, 0.4, 0.67, 0.52, 0.07, 0.23, 0.68, 0.19, 0.01, 0.32, 0.28, 0.04, 0.26, 0.67, 0.28, 0.34, 0.56, 0.72, 0.89, 0.89, 0.88, 0.76, 0.62, 0.87, 0.86, 0.73, 0.92, 0.82, 0.96, 0.98, 0.94, 0.98, 0.94, 0.97, 0.98, 1.0, 1.0, 1.0, 0.99, 1.0, 0.99, 1.0, 1.0, 1.0, 1.0, 1.0, 0.98, 0.96, 0.98, 0.95, 1.0, 1.0, 0.96, 1.0, 0.94, 0.99, 0.99, 0.99, 0.99, 0.96, 0.98, 0.78, 0.92, 0.73, 0.75, 0.69, 0.84, 0.75, 0.85, 0.82, 0.89, 0.9, 0.25, 0.56, 0.53, 0.37, 0.79, 0.6, 0.02, 0.49, 0.13, 0.38, 0.77, 0.24, 0.18, 0.09, 0.26, 0.35, 0.62, 0.4, 0.2, 0.47, 0.17, 0.09, 0.73, 0.07, 0.08, 0.11, 0.02, 0.23, 0.45, 0.76, 0.39, 1.0, 0.7, 0.84, 0.64, 0.03, 0.49, 0.02, 0.6, 0.06, 0.65, 0.04, 0.67, 0.04, 0.48, 0.67, 0.68, 0.16, 0.11, 0.62, 0.31, 0.0, 0.48, 0.71, 0.12, 0.63, 0.46, 0.78, 0.62, 0.92, 0.98, 0.66, 0.84, 0.36, 0.56, 0.27, 0.17, 0.07, 0.03, 0.0, 0.05, 0.0, 0.05, 0.01, 0.01, 0.18, 0.2, 0.49, 0.52, 0.87, 0.64, 0.55, 0.08, 0.65, 0.16, 0.38, 0.09, 0.06, 0.29, 0.52, 0.06, 0.38, 0.0, 0.39, 0.0, 0.2, 0.7, 0.63, 0.59, 0.02, 0.79, 0.24, 0.27, 0.71, 0.57, 0.58, 0.85, 0.59, 0.89, 0.79, 1.0, 0.96, 0.41, 0.8, 0.53, 0.73, 0.25, 0.28, 0.33, 0.36, 0.29, 0.04, 0.38, 0.0, 0.05, 0.75, 0.2, 0.17, 0.44, 0.22, 0.28, 0.43, 0.9, 0.45, 0.5, 0.0, 0.36, 0.0, 0.18, 0.0, 0.23, 0.01, 0.13, 0.41, 0.35, 0.6, 0.56, 0.48, 0.57, 0.01, 0.01, 0.0, 0.01, 0.0, 0.1, 0.01, 0.01, 0.41, 0.4, 0.07, 0.49, 0.04, 0.51, 0.39, 0.01, 0.12, 0.58, 0.39, 0.01, 0.44, 0.79, 0.49, 0.42, 0.59, 0.36, 0.56, 0.17, 0.52, 0.47, 0.01, 0.38, 0.52, 0.19, 0.02, 0.65, 0.7, 0.38, 0.04, 0.63, 0.59, 0.59, 0.91, 0.91, 0.45, 0.98, 0.79, 0.54, 0.47, 0.6, 0.28, 0.16, 0.51, 0.07, 0.25, 0.0, 0.24, 0.01, 0.27, 0.35, 0.29, 0.7, 0.46, 0.28, 0.05, 0.68, 0.05, 0.0, 0.0, 0.08, 0.03, 0.53, 0.64, 0.08, 0.53, 0.17, 0.07, 0.2, 0.0, 0.0, 0.06, 0.01, 0.28, 0.25, 0.0, 0.0, 0.49, 0.39, 0.0, 0.41, 0.72, 0.66, 0.4, 0.37, 0.14, 0.31, 0.0, 0.29, 0.4, 0.37, 0.75, 0.56, 0.63, 0.0, 0.34, 0.09, 0.58, 0.15, 0.03, 0.18, 0.04, 0.0, 0.05, 0.05, 0.01, 0.33, 0.42, 0.02, 0.17, 0.79, 0.7, 0.09, 0.84, 0.95, 0.07, 0.52, 0.37, 0.0, 0.25, 0.0, 0.31, 0.66, 0.79, 0.5, 0.41, 0.37, 0.42, 0.52, 0.28, 0.91, 0.88, 0.8, 0.89, 0.75, 0.76, 0.77, 0.79, 0.8, 0.76, 0.89, 0.98, 0.88, 0.89, 0.96, 0.98, 1.0, 1.0, 1.0, 1.0, 0.98, 1.0, 0.95, 0.96, 0.98, 0.97, 0.99, 1.0, 0.94, 1.0, 0.78, 0.94, 0.96, 0.91, 0.92, 0.94, 0.82, 0.83, 0.73, 0.69, 0.57, 0.78, 0.64, 0.7, 0.9, 0.82, 0.87, 0.79, 0.92, 0.88, 0.96, 0.98, 1.0, 0.99, 0.99, 1.0, 1.0, 1.0, 0.98, 1.0, 0.94, 1.0, 0.99, 0.99, 1.0, 0.95, 0.98, 0.96, 0.97, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 0.91, 1.0, 0.91, 1.0, 1.0, 1.0, 0.94, 1.0, 0.92, 1.0, 0.92, 1.0, 0.94, 1.0, 0.98, 1.0, 1.0, 0.97, 1.0, 0.98, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 0.98, 0.98, 0.94, 0.98, 0.96, 0.98, 0.97, 0.92, 0.96, 0.93, 0.93, 0.79, 0.95, 0.92, 0.91, 0.99, 0.94, 0.72, 0.72, 0.57, 0.52, 0.69, 0.89, 0.9, 0.68, 0.82, 0.97, 0.89, 1.0, 0.95, 0.98, 0.97, 0.87, 0.88, 0.81, 0.94, 0.88, 0.95, 1.0, 0.99, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 0.96, 0.99, 0.95, 0.99, 0.98, 0.98, 1.0, 0.91, 0.98, 0.94, 0.99, 1.0, 1.0, 0.99, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 0.99, 1.0, 1.0, 1.0, 1.0, 0.99, 1.0, 0.99, 0.99, 1.0, 1.0, 1.0, 0.99, 1.0, 0.99, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 0.95, 1.0, 0.95, 1.0, 1.0, 1.0, 1.0, 1.0, 0.99, 1.0, 1.0, 1.0, 1.0, 0.95, 0.98, 0.96, 0.98, 0.91, 0.95, 0.91, 0.91, 0.92, 0.93, 1.0]
RING finger
Part of a complex consisting of TRIM27, USP7 and MAGEL2
null
null
EID1, MAGED4, MAGEF1, SQSTM1, EPC1, CHD4, MAGEL2, PML, EIF3S6, PTPN11, USP7,
PIK3C2B, WASHC1, TBK1, NOD2,ULK1, STK38L
48, 63
null
null
Homomultimerizes
null
88.603957
0.43115
69.434952
0.612771
1,130
P15731
Q06224
32009536
UbiBrowser
UBC4
MSSSKRIAKELSDLERDPPTSCSAGPVGDDLYHWQASIMGPADSPYAGGVFFLSIHFPTDYPFKPPKISFTTKIYHPNINANGNICLDILKDQWSPALTLSKVLLSICSLLTDANPDDPLVPEIAHIYKTDRPKYEATAREWTKKYAV
Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
null
Not found
{}
1QCQ, 5AIE, 8J1R
{}
YSH1
MERTNTTTFKFFSLGGSNEVGRSCHILQYKGKTVMLDAGIHPAYQGLASLPFYDEFDLSKVDILLISHFHLDHAASLPYVMQRTNFQGRVFMTHPTKAIYRWLLRDFVRVTSIGSSSSSMGTKDEGLFSDEDLVDSFDKIETVDYHSTVDVNGIKFTAFHAGHVLGAAMFQIEIAGLRVLFTGDYSREVDRHLNSAEVPPLSSNVLIVESTFGTATHEPRLNRERKLTQLIHSTVMRGGRVLLPVFALGRAQEIMLILDEYWSQHADELGGGQVPIFYASNLAKKCMSVFQTYVNMMNDDIRKKFRDSQTNPFIFKNISYLRNLEDFQDFGPSVMLASPGMLQSGLSRDLLERWCPEDKNLVLITGYSIEGTMAKFIMLEPDTIPSINNPEITIPRRCQVEEISFAAHVDFQENLEFIEKISAPNIILVHGEANPMGRLKSALLSNFASLKGTDNEVHVFNPRNCVEVDLEFQGVKVAKAVGNIVNEIYKEENVEIKEEIAAKIEPIKEENEDNLDSQAEKGLVDEEEHKDIVVSGILVSDDKNFELDFLSLSDLREHHPDLSTTILRERQSVRVNCKKELIYWHILQMFGEAEVLQDDDRVTNQEPKVKEESKDNLTNTGKLILQIMGDIKLTIVNTLAVVEWTQDLMNDTVADSIIAILMNVDSAPASVKLSSHSCDDHDHNNVQSNAQGKIDEVERVKQISRLFKEQFGDCFTLFLNKDEYASNKEETITGVVTIGKSTAKIDFNNMKILECNSNPLKGRVESLLNIGGNLVTPLC
Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
Nucleus
Not found
{}
6I1D
{}
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null
null
null
null
null
null
null
null
null
null
null
95.422365
0.345878
82.345918
0.370308
843
P15918
C9JYI4
19118899
UbiBrowser
RAG1
MAASFPPTLGLSSAPDEIQHPHIKFSEWKFKLFRVRSFEKTPEEAQKEKKDSFEGKPSLEQSPAVLDKADGQKPVPTQPLLKAHPKFSKKFHDNEKARGKAIHQANLRHLCRICGNSFRADEHNRRYPVHGPVDGKTLGLLRKKEKRATSWPDLIAKVFRIDVKADVDSIHPTEFCHNCWSIMHRKFSSAPCEVYFPRNVTMEWHPHTPSCDICNTARRGLKRKSLQPNLQLSKKLKTVLDQARQARQHKRRAQARISSKDVMKKIANCSKIHLSTKLLAVDFPEHFVKSISCQICEHILADPVETNCKHVFCRVCILRCLKVMGSYCPSCRYPCFPTDLESPVKSFLSVLNSLMVKCPAKECNEEVSLEKYNHHISSHKESKEIFVHINKGGRPRQHLLSLTRRAQKHRLRELKLQVKAFADKEEGGDVKSVCMTLFLLALRARNEHRQADELEAIMQGKGSGLQPAVCLAIRVNTFLSCSQYHKMYRTVKAITGRQIFQPLHALRNAEKVLLPGYHHFEWQPPLKNVSSSTDVGIIDGLSGLSSSVDDYPVDTIAKRFRYDSALVSALMDMEEDILEGMRSQDLDDYLNGPFTVVVKESCDGMGDVSEKHGSGPVVPEKAVRFSFTIMKITIAHSSQNVKVFEEAKPNSELCCKPLCLMLADESDHETLTAILSPLIAEREAMKSSELMLELGGILRTFKFIFRGTGYDEKLVREVEGLEASGSVYICTLCDATRLEASQNLVFHSITRSHAENLERYEVWRSNPYHESVEELRDRVKGVSAKPFIETVPSIDALHCDIGNAAEFYKIFQLEIGEVYKNPNASKEERKRWQATLDKHLRKKMNLKPIMRMNGNFARKLMTKETVDAVCELIPSEERHEALRELMDLYLKMKPVWRSSCPAKECPESLCQYSFNSQRFAELLSTKFKYRYEGKITNYFHKTLAHVPEIIERDGSIGAWASEGNESGNKLFRRFRKMNARQSKCYEMEDVLKHHWLYTSKYLQKFMNAHNALKTSGFTMNPQASLGDPLGIEDSLESQDSMEF
Homo sapiens
Nucleus
Tissue enriched (lymphoid)
{'Ciliated cells': '0.4', 'Basal respiratory cells': '0.5', 'Club cells': '0.7', 'Ionocytes': '0.0', 'Mucus glandular cells': '1.2', 'Serous glandular cells': '0.2', 'Gastric mucus-secreting cells': '0.0', 'Proximal enterocytes': '3.1', 'Paneth cells': '1.6', 'Distal enterocytes': '1.3', 'Intestinal goblet cells': '0.9', 'Exocrine glandular cells': '-0.280', 'Basal prostatic cells': '0.5', 'Prostatic glandular cells': '0.7', 'Breast glandular cells': '0.213', 'Breast myoepithelial cells': '0.124', 'Glandular and luminal cells': '0.4', 'Secretory cells': '1.1', 'Basal keratinocytes': '0.2', 'Suprabasal keratinocytes': '0.2', 'Basal squamous epithelial cells': '0.2', 'Squamous epithelial cells': '0.1', 'Alveolar cells type 1': '0.237', 'Alveolar cells type 2': '-0.054', 'Salivary duct cells': '1.6', 'Ductal cells': '0.483', 'Hepatocytes': '0.459', 'Cholangiocytes': '0.0', 'Proximal tubular cells': '0.265', 'Distal tubular cells': '3.1', 'Collecting duct cells': '1.9', 'Mesothelial cells': '0.203', 'Sertoli cells': '0.384', 'Granulosa cells': '1.5', 'Enteroendocrine cells': '0.4', 'Pancreatic endocrine cells': '1.7', 'Leydig cells': '0.164', 'Excitatory neurons': '1.7', 'Inhibitory neurons': '1.7', 'Cone photoreceptor cells': '0.0', 'Rod photoreceptor cells': '1.0', 'Bipolar cells': '0.9', 'Horizontal cells': '0.6', 'Astrocytes': '0.0', 'Oligodendrocyte precursor cells': '0.9', 'Oligodendrocytes': '1.2', 'Microglial cells': '0.9', 'Muller glia cells': '0.3', 'Schwann cells': '0.108', 'Spermatogonia': '0.242', 'Spermatocytes': '0.124', 'Early spermatids': '-0.095', 'Late spermatids': '-0.269', 'Oocytes': '0.0', 'Cytotrophoblasts': '0.2', 'Syncytiotrophoblasts': '0.2', 'Extravillous trophoblasts': '0.2', 'Endothelial cells': '1.9', 'Lymphatic endothelial cells': '1.3', 'Cardiomyocytes': '0.472', 'Skeletal myocytes': '-0.156', 'Smooth muscle cells': '0.6', 'Adipocytes': '1.4', 'Melanocytes': '0.021', 'Fibroblasts': '1.2', 'Peritubular cells': '0.295', 'Endometrial stromal cells': '0.3', 'Ovarian stromal cells': '0.3', 'Undifferentiated cells': '0.6', 'T-cells': '0.4', 'B-cells': '0.1', 'Plasma cells': '0.1', 'Nk-cells': '1.2', 'Granulocytes': '0.0', 'Monocytes': '0.2', 'Macrophages': '0.3', 'Hofbauer cells': '0.4', 'Kupffer cells': '1.2', 'Dendritic cells': '1.6', 'Langerhans cells': '0.138', 'Erythroid cells': '0.028', 'Adipocytes (Subcutaneous)': '-0.012', 'Adipocytes (Visceral)': '-0.165', 'Breast glandular cells (progenitors)': '0.098', 'Adipocytes (Breast)': '-0.171', 'Colon enterocytes': '0.078', 'Colon enteroendocrine cells': '0.143', 'Enteric glia cells': '0.152', 'Mitotic cells (Colon)': '0.062', 'Mitotic cells (Heart)': '0.397', 'Podocytes': '-0.072', 'Ascending Loop of Henle cells': '0.493', 'Intercalated cells': '0.034', 'Cholangiocyte': '0.092', 'NK-cells (Liver)': '-0.014', 'Respiratory ciliated cells': '0.040', 'Mitotic cells (Lung)': '0.062', 'NK-cells (Lung)': '0.045', 'B-cells (Lung)': '-0.132', 'Alpha cells': '0.314', 'Beta cells': '0.181', 'Prostate glandular cells': '-0.031', 'Prostate basal glandular cells': '0.313', 'Urothelial cells': '0.271', 'Keratinocyte (other)': '-0.231', 'Keratinocyte (granular)': '-0.135', 'Hair cortex cells': '0.246', 'Inner root sheath cells': '0.267', 'Outer root sheath cells': '0.338', 'Sebaceous gland cells': '0.259', 'Eccrine sweat gland cells': '0.376', 'Adipocytes (Skin)': '0.350', 'Mitotic cells (Skin)': '0.274', 'Parietal cells': '0.326', 'Chief cells': '0.192', 'Gastric mucous cells': '0.372', 'Gastric enteroendocrine cells': '0.286', 'Mitotic cells (Stomach)': '0.297', 'Parafollicular cells': '0.085', 'Thyroid glandular cells': '0.450', 'Mitotic cells (Thyroid)': '-0.059', 'Adrenal cortex cells': '0.592', 'Adrenal medulla cells': '-0.035', 'Mitotic cells (Adrenal gland)': '0.350', 'Minor salivary glandular cells': '0.608', 'Minor salivary gland ductal cells': '0.535', 'Minor salivary gland basal cells': '0.042', 'Mitotic cells (Minor salivary gland)': '0.035', 'Adipocytes (Minor salivary gland)': '0.177', 'Somatotropes': '0.024', 'Lactotropes': '-0.050', 'Gonadotropes': '0.102', 'Corticotropes': '-0.195', 'Thyrotropes': '0.165', 'Undifferentiated cells (Pituitary gland)': '0.287', 'Mitotic cells (Spleen)': '-0.234', 'Platelets': '-0.151', 'Erythrocytes': '-0.166', 'Hematopoietic stem cells': '-0.265', 'B-cells (Spleen)': '0.083', 'NK-cells (Spleen)': '0.264', 'Amygdala excitatory': '0.8', 'Cerebellar inhibitory': '0.6', 'Cge interneuron': '1.1', 'Deep-layer corticothalamic and 6b': '1.3', 'Deep-layer intratelencephalic': '1.5', 'Deep-layer near-projecting': '1.6', 'Eccentric medium spiny neuron': '0.5', 'Hippocampal ca1-3': '1.3', 'Hippocampal ca4': '0.3', 'Hippocampal dentate gyrus': '0.3', 'Lamp5-lhx6 and chandelier': '1.2', 'Lower rhombic lip': '2.9', 'Mammillary body': '2.6', 'Medium spiny neuron': '0.2', 'Mge interneuron': '1.8', 'Midbrain-derived inhibitory': '1.8', 'Miscellaneous': '1.1', 'Splatter': '2.1', 'Thalamic excitatory': '2.0', 'Upper rhombic lip': '0.4', 'Upper-layer intratelencephalic': '1.1', 'Astrocyte': '0.7', 'Bergmann glia': '1.4', 'Central nervous system macrophage': '1.5', 'Choroid plexus epithelial cell': '6.8', 'Committed oligodendrocyte precursor': '0.7', 'Ependymal cell': '0.5', 'Oligodendrocyte': '1.8', 'Oligodendrocyte precursor cell': '0.4', 'Endothelial cell': '6.8', 'Pericyte': '0.3', 'Vascular associated smooth muscle cell': '2.1', 'Fibroblast': '1.5', 'Leukocyte': '2.0', 'Basophil': '0.3', 'Eosinophil': '0.0', 'Neutrophil': '0.0', 'Classical monocyte': '0.0', 'Non-classical monocyte': '0.1', 'Intermediate monocyte': '0.0', 'T-reg': '0.1', 'GdT-cell': '0.0', 'MAIT T-cell': '0.3', 'Memory CD4 T-cell': '0.0', 'Naive CD4 T-cell': '0.4', 'Memory CD8 T-cell': '0.1', 'Naive CD8 T-cell': '0.3', 'Memory B-cell': '0.0', 'Naive B-cell': '0.4', 'Plasmacytoid DC': '0.0', 'Myeloid DC': '0.0', 'NK-cell': '2.3', 'Total PBMC': '0.1', 'Vd2 gdTCR': '0.0', 'Memory CD4 T-cell Th1\\/Th17': '0.8', 'Memory CD4 T-cell Th17': '0.4', 'Memory CD4 T-cell Th2': '0.4', 'Non-Vd2 gdTCR': '0.0', 'Memory CD4 T-cell Th1': '0.6', 'Memory CD4 T-cell TFH': '0.3', 'Terminal effector memory CD4 T-cell': '0.3', 'Central memory CD8 T-cell': '0.3', 'Effector memory CD8 T-cell': '0.2', 'Terminal effector memory CD8 T-cell': '0.1', 'Non-switched memory B-cell': '0.1', 'Plasmablast': '0.0', 'Switched memory B-cell': '0.0', 'Exhausted memory B-cell': '0.6', 'Progenitor cell': '0.5', 'Memory T-reg': '0.1', 'Naive CD4 T-cell activated': '0.1', 'Naive CD8 T-cell activated': '0.1', 'Naive T-reg': '0.6'}
null
{'Adipose Tissue': 0.4057857641196013, 'Adrenal Gland': 0.8675186046511627, 'Bladder': 0.3579738095238095, 'Blood': 0.2379831011840688, 'Blood Vessel': 0.2933549932584269, 'Brain': 0.1101639227857683, 'Breast': 0.4449297167755991, 'Cervix Uteri': 0.3465005263157895, 'Colon': 0.3597065468549422, 'Esophagus': 0.2373859999999999, 'Fallopian Tube': 0.4340344444444444, 'Heart': 0.1957524343786295, 'Kidney': 0.6407348314606741, 'Liver': 0.2803746017699115, 'Lung': 0.4784568079584775, 'Muscle': 0.0852849676214196, 'Nerve': 0.2672600161550889, 'Ovary': 0.3940442222222222, 'Pancreas': 0.2423982621951219, 'Pituitary': 0.2461227561837455, 'Prostate': 0.3530606122448979, 'Salivary Gland': 0.6816697530864197, 'Skin': 0.2567115765616362, 'Small Intestine': 0.5665286096256684, 'Spleen': 2.1116, 'Stomach': 0.3458365459610028, 'Testis': 0.8320800554016621, 'Thyroid': 1.571570045941807, 'Uterus': 0.4048269718309859, 'Vagina': 0.316294358974359}
KPNA1
MTTPGKENFRLKSYKNKSLNPDEMRRRREEEGLQLRKQKREEQLFKRRNVATAEEETEEEVMSDGGFHEAQISNMEMAPGGVITSDMIEMIFSKSPEQQLSATQKFRKLLSKEPNPPIDEVISTPGVVARFVEFLKRKENCTLQFESAWVLTNIASGNSLQTRIVIQAGAVPIFIELLSSEFEDVQEQAVWALGNIAGDSTMCRDYVLDCNILPPLLQLFSKQNRLTMTRNAVWALSNLCRGKSPPPEFAKVSPCLNVLSWLLFVSDTDVLADACWALSYLSDGPNDKIQAVIDAGVCRRLVELLMHNDYKVVSPALRAVGNIVTGDD
Homo sapiens
null
Not found
{}
null
{'Adipose Tissue': 16.96626411960133, 'Adrenal Gland': 14.503023255813954, 'Bladder': 19.097619047619048, 'Blood': 11.973662325080731, 'Blood Vessel': 21.979731835205992, 'Brain': 11.23245798637396, 'Breast': 16.390477124183008, 'Cervix Uteri': 19.95263157894737, 'Colon': 16.478482670089857, 'Esophagus': 16.09025259515571, 'Fallopian Tube': 18.56, 'Heart': 8.964315911730546, 'Kidney': 7.069955056179776, 'Liver': 8.114858407079646, 'Lung': 20.074091695501732, 'Muscle': 38.468493150684935, 'Nerve': 21.93856219709208, 'Ovary': 16.641433333333335, 'Pancreas': 5.830640243902439, 'Pituitary': 15.286901060070672, 'Prostate': 16.90897142857143, 'Salivary Gland': 12.801858024691358, 'Skin': 17.74252017689331, 'Small Intestine': 14.951620320855614, 'Spleen': 15.80356846473029, 'Stomach': 11.67091364902507, 'Testis': 18.677479224376732, 'Thyroid': 18.03396784073507, 'Uterus': 21.702042253521128, 'Vagina': 17.03802564102564}
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0.95, 0.95, 0.98, 0.9, 0.98, 0.83, 0.78, 0.79]
[36.16, 32.72, 34.16, 42.09, 43.19, 47.06, 35.62, 39.62, 40.62, 41.03, 40.75, 43.53, 47.31, 42.59, 49.31, 49.88, 44.09, 50.75, 55.94, 74.12, 63.06, 60.38, 61.19, 59.44, 64.06, 63.62, 67.06, 62.06, 58.53, 60.62, 55.31, 50.5, 53.25, 60.97, 53.34, 50.22, 57.41, 58.69, 57.44, 54.06, 56.22, 54.28, 56.91, 61.44, 78.94, 84.12, 87.5, 82.75, 80.38, 75.19, 54.72, 41.19, 34.97, 30.95, 42.31, 41.03, 31.98, 36.91, 46.41, 36.97, 35.12, 43.19, 37.34, 34.19, 33.38, 33.16, 35.22, 35.0, 35.19, 29.86, 34.09, 43.94, 34.41, 35.66, 42.19, 36.09, 38.56, 38.53, 41.5, 51.94, 63.75, 81.25, 89.5, 91.5, 92.0, 94.06, 96.0, 96.25, 96.56, 97.5, 97.56, 97.88, 97.44, 96.19, 97.5, 95.81, 96.88, 97.69, 98.38, 97.56, 97.44, 97.81, 98.0, 96.81, 95.94, 96.81, 96.12, 93.06, 93.31, 92.62, 89.75, 86.31, 79.5, 70.06, 80.62, 89.31, 93.69, 94.81, 94.88, 93.81, 95.62, 95.62, 95.31, 95.19, 95.25, 96.0, 97.38, 98.25, 98.5, 98.56, 98.69, 98.69, 98.56, 98.69, 98.56, 98.0, 96.44, 94.62, 93.44, 94.38, 95.62, 97.25, 98.06, 98.0, 98.19, 98.19, 98.56, 98.56, 98.25, 98.38, 98.56, 98.12, 97.0, 97.19, 96.62, 94.38, 92.62, 93.69, 94.62, 95.81, 96.81, 97.5, 97.0, 98.25, 98.44, 98.31, 98.12, 98.19, 98.44, 98.69, 98.81, 98.81, 98.81, 98.88, 98.81, 98.62, 98.56, 98.44, 97.0, 96.88, 95.44, 95.62, 94.56, 95.44, 97.69, 97.94, 97.31, 98.19, 98.69, 98.62, 97.88, 98.62, 98.81, 98.31, 98.38, 98.5, 98.06, 96.12, 96.0, 94.75, 95.88, 96.75, 98.0, 98.44, 98.56, 98.75, 98.81, 98.81, 98.62, 98.69, 98.44, 98.75, 98.5, 98.38, 98.38, 98.5, 98.06, 97.31, 96.62, 95.12, 89.31, 85.62, 83.81, 86.38, 92.94, 94.56, 95.31, 96.12, 97.25, 97.12, 97.25, 98.25, 98.44, 98.19, 98.62, 98.62, 98.25, 98.5, 98.62, 97.94, 93.25, 89.12, 81.38, 86.12, 92.25, 93.19, 97.12, 98.0, 97.94, 98.19, 98.44, 98.56, 98.19, 98.56, 98.44, 98.62, 97.12, 98.31, 98.69, 98.44, 96.94, 98.12, 98.44, 97.69, 96.19, 95.56, 97.88, 97.62, 95.75, 98.31, 98.62, 97.75, 98.31, 98.75, 98.62, 98.19, 98.38, 98.56, 96.94, 96.31, 97.0, 95.5, 92.19, 89.62, 92.06, 93.38, 95.75, 95.31, 95.62, 97.94, 98.31, 98.19, 97.81, 98.31, 98.19, 98.0, 98.44, 98.19, 98.38, 98.62, 98.62, 98.56, 98.62, 98.56, 98.25, 98.31, 98.31, 97.56, 96.06, 94.5, 93.94, 97.69, 97.06, 93.69, 95.88, 97.75, 95.12, 92.88, 94.94, 96.94, 92.25, 91.25, 93.19, 92.62, 88.0, 78.5, 80.06, 57.25]
[0.99, 0.96, 0.96, 0.93, 0.95, 1.0, 1.0, 0.65, 0.95, 0.89, 0.84, 0.93, 0.91, 0.86, 0.98, 0.82, 0.87, 0.97, 0.4, 0.53, 0.66, 0.66, 0.4, 0.39, 0.64, 0.63, 0.47, 0.7, 0.5, 0.44, 0.56, 0.29, 0.62, 0.67, 0.61, 0.72, 0.63, 0.52, 0.64, 0.75, 0.39, 0.31, 0.67, 0.77, 0.24, 0.13, 0.38, 0.33, 0.07, 0.4, 0.32, 0.5, 0.65, 0.76, 0.38, 0.59, 0.56, 0.73, 0.39, 0.63, 0.81, 0.88, 0.55, 0.96, 0.69, 0.98, 0.98, 0.89, 0.72, 0.92, 0.85, 0.77, 0.88, 0.86, 0.79, 0.89, 0.97, 0.68, 0.97, 0.75, 0.65, 0.39, 0.16, 0.35, 0.63, 0.5, 0.07, 0.34, 0.69, 0.12, 0.0, 0.46, 0.14, 0.91, 0.33, 0.44, 0.79, 0.42, 0.05, 0.22, 0.33, 0.0, 0.0, 0.33, 0.41, 0.0, 0.03, 0.52, 0.13, 0.0, 0.1, 0.61, 0.76, 0.89, 0.96, 0.1, 0.18, 0.04, 0.53, 0.4, 0.0, 0.18, 0.69, 0.15, 0.78, 0.44, 0.0, 0.07, 0.53, 0.15, 0.0, 0.04, 0.51, 0.02, 0.01, 0.61, 0.4, 0.68, 0.7, 0.25, 0.33, 0.46, 0.01, 0.02, 0.25, 0.05, 0.0, 0.0, 0.04, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.13, 0.19, 0.46, 0.38, 0.65, 0.07, 0.0, 0.56, 0.23, 0.0, 0.16, 0.79, 0.3, 0.33, 0.0, 0.01, 0.4, 0.1, 0.0, 0.1, 0.6, 0.06, 0.02, 0.72, 0.19, 0.96, 0.39, 0.41, 0.46, 0.02, 0.03, 0.16, 0.04, 0.0, 0.01, 0.18, 0.01, 0.01, 0.01, 0.0, 0.0, 0.05, 0.06, 0.06, 0.44, 0.23, 0.83, 0.08, 0.01, 0.32, 0.37, 0.0, 0.06, 0.54, 0.27, 0.63, 0.02, 0.08, 0.69, 0.2, 0.02, 0.14, 0.57, 0.05, 0.09, 0.68, 0.53, 0.98, 0.26, 0.55, 0.46, 0.45, 0.04, 0.16, 0.33, 0.09, 0.01, 0.0, 0.04, 0.04, 0.0, 0.05, 0.03, 0.01, 0.03, 0.26, 0.36, 0.62, 0.87, 0.58, 0.58, 0.09, 0.55, 0.19, 0.64, 0.35, 0.02, 0.29, 0.48, 0.01, 0.06, 0.7, 0.13, 0.0, 0.16, 0.48, 0.0, 0.0, 0.69, 0.26, 0.86, 0.15, 0.29, 0.4, 0.0, 0.03, 0.11, 0.12, 0.0, 0.0, 0.33, 0.0, 0.0, 0.0, 0.22, 0.03, 0.02, 0.29, 0.48, 0.57, 0.36, 0.66, 0.16, 0.03, 0.5, 0.24, 0.01, 0.39, 0.68, 0.17, 0.56, 0.01, 0.33, 0.76, 0.22, 0.0, 0.55, 0.42, 0.02, 0.27, 0.85, 0.3, 0.9, 0.33, 0.74, 0.58, 0.0, 0.2, 0.5, 0.01, 0.0, 0.58, 0.38, 0.0, 0.2, 0.42, 0.16, 0.15, 0.73, 0.65, 0.34, 0.78, 1.0]
RING finger
Component of the RAG complex composed of core components RAG1 and RAG2, and associated component HMGB1 or HMGB2.
RAG
null
DCAF1,RAG1 , RAG2, HMGB1 or HMGB2,
H3
mono
null
null
Homodimer
null
81.264161
0.423183
84.346402
0.379055
1,451
P15918
P04637
27249653
DegPred
RAG1
MAASFPPTLGLSSAPDEIQHPHIKFSEWKFKLFRVRSFEKTPEEAQKEKKDSFEGKPSLEQSPAVLDKADGQKPVPTQPLLKAHPKFSKKFHDNEKARGKAIHQANLRHLCRICGNSFRADEHNRRYPVHGPVDGKTLGLLRKKEKRATSWPDLIAKVFRIDVKADVDSIHPTEFCHNCWSIMHRKFSSAPCEVYFPRNVTMEWHPHTPSCDICNTARRGLKRKSLQPNLQLSKKLKTVLDQARQARQHKRRAQARISSKDVMKKIANCSKIHLSTKLLAVDFPEHFVKSISCQICEHILADPVETNCKHVFCRVCILRCLKVMGSYCPSCRYPCFPTDLESPVKSFLSVLNSLMVKCPAKECNEEVSLEKYNHHISSHKESKEIFVHINKGGRPRQHLLSLTRRAQKHRLRELKLQVKAFADKEEGGDVKSVCMTLFLLALRARNEHRQADELEAIMQGKGSGLQPAVCLAIRVNTFLSCSQYHKMYRTVKAITGRQIFQPLHALRNAEKVLLPGYHHFEWQPPLKNVSSSTDVGIIDGLSGLSSSVDDYPVDTIAKRFRYDSALVSALMDMEEDILEGMRSQDLDDYLNGPFTVVVKESCDGMGDVSEKHGSGPVVPEKAVRFSFTIMKITIAHSSQNVKVFEEAKPNSELCCKPLCLMLADESDHETLTAILSPLIAEREAMKSSELMLELGGILRTFKFIFRGTGYDEKLVREVEGLEASGSVYICTLCDATRLEASQNLVFHSITRSHAENLERYEVWRSNPYHESVEELRDRVKGVSAKPFIETVPSIDALHCDIGNAAEFYKIFQLEIGEVYKNPNASKEERKRWQATLDKHLRKKMNLKPIMRMNGNFARKLMTKETVDAVCELIPSEERHEALRELMDLYLKMKPVWRSSCPAKECPESLCQYSFNSQRFAELLSTKFKYRYEGKITNYFHKTLAHVPEIIERDGSIGAWASEGNESGNKLFRRFRKMNARQSKCYEMEDVLKHHWLYTSKYLQKFMNAHNALKTSGFTMNPQASLGDPLGIEDSLESQDSMEF
Homo sapiens
Nucleus
Tissue enriched (lymphoid)
{'Ciliated cells': '0.4', 'Basal respiratory cells': '0.5', 'Club cells': '0.7', 'Ionocytes': '0.0', 'Mucus glandular cells': '1.2', 'Serous glandular cells': '0.2', 'Gastric mucus-secreting cells': '0.0', 'Proximal enterocytes': '3.1', 'Paneth cells': '1.6', 'Distal enterocytes': '1.3', 'Intestinal goblet cells': '0.9', 'Exocrine glandular cells': '-0.280', 'Basal prostatic cells': '0.5', 'Prostatic glandular cells': '0.7', 'Breast glandular cells': '0.213', 'Breast myoepithelial cells': '0.124', 'Glandular and luminal cells': '0.4', 'Secretory cells': '1.1', 'Basal keratinocytes': '0.2', 'Suprabasal keratinocytes': '0.2', 'Basal squamous epithelial cells': '0.2', 'Squamous epithelial cells': '0.1', 'Alveolar cells type 1': '0.237', 'Alveolar cells type 2': '-0.054', 'Salivary duct cells': '1.6', 'Ductal cells': '0.483', 'Hepatocytes': '0.459', 'Cholangiocytes': '0.0', 'Proximal tubular cells': '0.265', 'Distal tubular cells': '3.1', 'Collecting duct cells': '1.9', 'Mesothelial cells': '0.203', 'Sertoli cells': '0.384', 'Granulosa cells': '1.5', 'Enteroendocrine cells': '0.4', 'Pancreatic endocrine cells': '1.7', 'Leydig cells': '0.164', 'Excitatory neurons': '1.7', 'Inhibitory neurons': '1.7', 'Cone photoreceptor cells': '0.0', 'Rod photoreceptor cells': '1.0', 'Bipolar cells': '0.9', 'Horizontal cells': '0.6', 'Astrocytes': '0.0', 'Oligodendrocyte precursor cells': '0.9', 'Oligodendrocytes': '1.2', 'Microglial cells': '0.9', 'Muller glia cells': '0.3', 'Schwann cells': '0.108', 'Spermatogonia': '0.242', 'Spermatocytes': '0.124', 'Early spermatids': '-0.095', 'Late spermatids': '-0.269', 'Oocytes': '0.0', 'Cytotrophoblasts': '0.2', 'Syncytiotrophoblasts': '0.2', 'Extravillous trophoblasts': '0.2', 'Endothelial cells': '1.9', 'Lymphatic endothelial cells': '1.3', 'Cardiomyocytes': '0.472', 'Skeletal myocytes': '-0.156', 'Smooth muscle cells': '0.6', 'Adipocytes': '1.4', 'Melanocytes': '0.021', 'Fibroblasts': '1.2', 'Peritubular cells': '0.295', 'Endometrial stromal cells': '0.3', 'Ovarian stromal cells': '0.3', 'Undifferentiated cells': '0.6', 'T-cells': '0.4', 'B-cells': '0.1', 'Plasma cells': '0.1', 'Nk-cells': '1.2', 'Granulocytes': '0.0', 'Monocytes': '0.2', 'Macrophages': '0.3', 'Hofbauer cells': '0.4', 'Kupffer cells': '1.2', 'Dendritic cells': '1.6', 'Langerhans cells': '0.138', 'Erythroid cells': '0.028', 'Adipocytes (Subcutaneous)': '-0.012', 'Adipocytes (Visceral)': '-0.165', 'Breast glandular cells (progenitors)': '0.098', 'Adipocytes (Breast)': '-0.171', 'Colon enterocytes': '0.078', 'Colon enteroendocrine cells': '0.143', 'Enteric glia cells': '0.152', 'Mitotic cells (Colon)': '0.062', 'Mitotic cells (Heart)': '0.397', 'Podocytes': '-0.072', 'Ascending Loop of Henle cells': '0.493', 'Intercalated cells': '0.034', 'Cholangiocyte': '0.092', 'NK-cells (Liver)': '-0.014', 'Respiratory ciliated cells': '0.040', 'Mitotic cells (Lung)': '0.062', 'NK-cells (Lung)': '0.045', 'B-cells (Lung)': '-0.132', 'Alpha cells': '0.314', 'Beta cells': '0.181', 'Prostate glandular cells': '-0.031', 'Prostate basal glandular cells': '0.313', 'Urothelial cells': '0.271', 'Keratinocyte (other)': '-0.231', 'Keratinocyte (granular)': '-0.135', 'Hair cortex cells': '0.246', 'Inner root sheath cells': '0.267', 'Outer root sheath cells': '0.338', 'Sebaceous gland cells': '0.259', 'Eccrine sweat gland cells': '0.376', 'Adipocytes (Skin)': '0.350', 'Mitotic cells (Skin)': '0.274', 'Parietal cells': '0.326', 'Chief cells': '0.192', 'Gastric mucous cells': '0.372', 'Gastric enteroendocrine cells': '0.286', 'Mitotic cells (Stomach)': '0.297', 'Parafollicular cells': '0.085', 'Thyroid glandular cells': '0.450', 'Mitotic cells (Thyroid)': '-0.059', 'Adrenal cortex cells': '0.592', 'Adrenal medulla cells': '-0.035', 'Mitotic cells (Adrenal gland)': '0.350', 'Minor salivary glandular cells': '0.608', 'Minor salivary gland ductal cells': '0.535', 'Minor salivary gland basal cells': '0.042', 'Mitotic cells (Minor salivary gland)': '0.035', 'Adipocytes (Minor salivary gland)': '0.177', 'Somatotropes': '0.024', 'Lactotropes': '-0.050', 'Gonadotropes': '0.102', 'Corticotropes': '-0.195', 'Thyrotropes': '0.165', 'Undifferentiated cells (Pituitary gland)': '0.287', 'Mitotic cells (Spleen)': '-0.234', 'Platelets': '-0.151', 'Erythrocytes': '-0.166', 'Hematopoietic stem cells': '-0.265', 'B-cells (Spleen)': '0.083', 'NK-cells (Spleen)': '0.264', 'Amygdala excitatory': '0.8', 'Cerebellar inhibitory': '0.6', 'Cge interneuron': '1.1', 'Deep-layer corticothalamic and 6b': '1.3', 'Deep-layer intratelencephalic': '1.5', 'Deep-layer near-projecting': '1.6', 'Eccentric medium spiny neuron': '0.5', 'Hippocampal ca1-3': '1.3', 'Hippocampal ca4': '0.3', 'Hippocampal dentate gyrus': '0.3', 'Lamp5-lhx6 and chandelier': '1.2', 'Lower rhombic lip': '2.9', 'Mammillary body': '2.6', 'Medium spiny neuron': '0.2', 'Mge interneuron': '1.8', 'Midbrain-derived inhibitory': '1.8', 'Miscellaneous': '1.1', 'Splatter': '2.1', 'Thalamic excitatory': '2.0', 'Upper rhombic lip': '0.4', 'Upper-layer intratelencephalic': '1.1', 'Astrocyte': '0.7', 'Bergmann glia': '1.4', 'Central nervous system macrophage': '1.5', 'Choroid plexus epithelial cell': '6.8', 'Committed oligodendrocyte precursor': '0.7', 'Ependymal cell': '0.5', 'Oligodendrocyte': '1.8', 'Oligodendrocyte precursor cell': '0.4', 'Endothelial cell': '6.8', 'Pericyte': '0.3', 'Vascular associated smooth muscle cell': '2.1', 'Fibroblast': '1.5', 'Leukocyte': '2.0', 'Basophil': '0.3', 'Eosinophil': '0.0', 'Neutrophil': '0.0', 'Classical monocyte': '0.0', 'Non-classical monocyte': '0.1', 'Intermediate monocyte': '0.0', 'T-reg': '0.1', 'GdT-cell': '0.0', 'MAIT T-cell': '0.3', 'Memory CD4 T-cell': '0.0', 'Naive CD4 T-cell': '0.4', 'Memory CD8 T-cell': '0.1', 'Naive CD8 T-cell': '0.3', 'Memory B-cell': '0.0', 'Naive B-cell': '0.4', 'Plasmacytoid DC': '0.0', 'Myeloid DC': '0.0', 'NK-cell': '2.3', 'Total PBMC': '0.1', 'Vd2 gdTCR': '0.0', 'Memory CD4 T-cell Th1\\/Th17': '0.8', 'Memory CD4 T-cell Th17': '0.4', 'Memory CD4 T-cell Th2': '0.4', 'Non-Vd2 gdTCR': '0.0', 'Memory CD4 T-cell Th1': '0.6', 'Memory CD4 T-cell TFH': '0.3', 'Terminal effector memory CD4 T-cell': '0.3', 'Central memory CD8 T-cell': '0.3', 'Effector memory CD8 T-cell': '0.2', 'Terminal effector memory CD8 T-cell': '0.1', 'Non-switched memory B-cell': '0.1', 'Plasmablast': '0.0', 'Switched memory B-cell': '0.0', 'Exhausted memory B-cell': '0.6', 'Progenitor cell': '0.5', 'Memory T-reg': '0.1', 'Naive CD4 T-cell activated': '0.1', 'Naive CD8 T-cell activated': '0.1', 'Naive T-reg': '0.6'}
null
{'Adipose Tissue': 0.4057857641196013, 'Adrenal Gland': 0.8675186046511627, 'Bladder': 0.3579738095238095, 'Blood': 0.2379831011840688, 'Blood Vessel': 0.2933549932584269, 'Brain': 0.1101639227857683, 'Breast': 0.4449297167755991, 'Cervix Uteri': 0.3465005263157895, 'Colon': 0.3597065468549422, 'Esophagus': 0.2373859999999999, 'Fallopian Tube': 0.4340344444444444, 'Heart': 0.1957524343786295, 'Kidney': 0.6407348314606741, 'Liver': 0.2803746017699115, 'Lung': 0.4784568079584775, 'Muscle': 0.0852849676214196, 'Nerve': 0.2672600161550889, 'Ovary': 0.3940442222222222, 'Pancreas': 0.2423982621951219, 'Pituitary': 0.2461227561837455, 'Prostate': 0.3530606122448979, 'Salivary Gland': 0.6816697530864197, 'Skin': 0.2567115765616362, 'Small Intestine': 0.5665286096256684, 'Spleen': 2.1116, 'Stomach': 0.3458365459610028, 'Testis': 0.8320800554016621, 'Thyroid': 1.571570045941807, 'Uterus': 0.4048269718309859, 'Vagina': 0.316294358974359}
TP53
MEEPQSDPSVEPPLSQETFSDLWKLLPENNVLSPLPSQAMDDLMLSPDDIEQWFTEDPGPDEAPRMPEAAPPVAPAPAAPTPAAPAPAPSWPLSSSVPSQKTYQGSYGFRLGFLHSGTAKSVTCTYSPALNKMFCQLAKTCPVQLWVDSTPPPGTRVRAMAIYKQSQHMTEVVRRCPHHERCSDSDGLAPPQHLIRVEGNLRVEYLDDRNTFRHSVVVPYEPPEVGSDCTTIHYNYMCNSSCMGGMNRRPILTIITLEDSSGNLLGRNSFEVRVCACPGRDRRTEEENLRKKGEPHHELPPGSTKRALPNNTSSSPQPKKKPLDGEYFTLQIRGRERFEMFRELNEALELKDAQAGKEPGGSRAHSSHLKSKKGQSTSRHKKLMFKTEGPDSD
Homo sapiens
Cytoplasm, Nucleus, Nucleus, PML body, Endoplasmic reticulum, Mitochondrion matrix, Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, Nucleus, Cytoplasm, Nucleus, Cytoplasm, Nucleus, Cytoplasm, Nucleus, Cytoplasm, Nucleus, Cytoplasm, Nucleus, Cytoplasm, Cytoplasm
Low tissue specificity
{'Ciliated cells': '9.7', 'Basal respiratory cells': '24.5', 'Club cells': '17.3', 'Ionocytes': '15.5', 'Mucus glandular cells': '17.4', 'Serous glandular cells': '17.1', 'Gastric mucus-secreting cells': '11.2', 'Proximal enterocytes': '10.3', 'Paneth cells': '26.0', 'Distal enterocytes': '18.1', 'Intestinal goblet cells': '35.3', 'Exocrine glandular cells': '-0.708', 'Basal prostatic cells': '22.3', 'Prostatic glandular cells': '18.3', 'Breast glandular cells': '0.568', 'Breast myoepithelial cells': '0.559', 'Glandular and luminal cells': '21.5', 'Secretory cells': '38.8', 'Basal keratinocytes': '34.6', 'Suprabasal keratinocytes': '32.5', 'Basal squamous epithelial cells': '31.0', 'Squamous epithelial cells': '34.2', 'Alveolar cells type 1': '-0.172', 'Alveolar cells type 2': '0.210', 'Salivary duct cells': '19.8', 'Ductal cells': '0.627', 'Hepatocytes': '0.473', 'Cholangiocytes': '24.8', 'Proximal tubular cells': '0.199', 'Distal tubular cells': '15.4', 'Collecting duct cells': '21.4', 'Mesothelial cells': '0.355', 'Sertoli cells': '0.685', 'Granulosa cells': '20.0', 'Enteroendocrine cells': '29.3', 'Pancreatic endocrine cells': '20.4', 'Leydig cells': '0.655', 'Excitatory neurons': '2.0', 'Inhibitory neurons': '3.0', 'Cone photoreceptor cells': '5.1', 'Rod photoreceptor cells': '7.6', 'Bipolar cells': '5.3', 'Horizontal cells': '2.5', 'Astrocytes': '15.5', 'Oligodendrocyte precursor cells': '8.5', 'Oligodendrocytes': '7.4', 'Microglial cells': '7.2', 'Muller glia cells': '9.8', 'Schwann cells': '0.115', 'Spermatogonia': '0.447', 'Spermatocytes': '0.010', 'Early spermatids': '-0.537', 'Late spermatids': '-0.647', 'Oocytes': '4.4', 'Cytotrophoblasts': '39.7', 'Syncytiotrophoblasts': '20.4', 'Extravillous trophoblasts': '40.6', 'Endothelial cells': '26.1', 'Lymphatic endothelial cells': '20.1', 'Cardiomyocytes': '0.292', 'Skeletal myocytes': '-0.271', 'Smooth muscle cells': '18.8', 'Adipocytes': '22.1', 'Melanocytes': '0.378', 'Fibroblasts': '15.8', 'Peritubular cells': '0.544', 'Endometrial stromal cells': '28.3', 'Ovarian stromal cells': '20.5', 'Undifferentiated cells': '65.7', 'T-cells': '20.5', 'B-cells': '28.3', 'Plasma cells': '12.2', 'Nk-cells': '24.3', 'Granulocytes': '15.2', 'Monocytes': '23.2', 'Macrophages': '22.3', 'Hofbauer cells': '25.4', 'Kupffer cells': '28.1', 'Dendritic cells': '37.3', 'Langerhans cells': '0.416', 'Erythroid cells': '-0.142', 'Adipocytes (Subcutaneous)': '-0.285', 'Adipocytes (Visceral)': '-0.318', 'Breast glandular cells (progenitors)': '0.579', 'Adipocytes (Breast)': '-0.562', 'Colon enterocytes': '0.130', 'Colon enteroendocrine cells': '0.043', 'Enteric glia cells': '-0.338', 'Mitotic cells (Colon)': '0.199', 'Mitotic cells (Heart)': '0.516', 'Podocytes': '-0.175', 'Ascending Loop of Henle cells': '0.423', 'Intercalated cells': '-0.083', 'Cholangiocyte': '0.275', 'NK-cells (Liver)': '-0.251', 'Respiratory ciliated cells': '-0.071', 'Mitotic cells (Lung)': '0.244', 'NK-cells (Lung)': '-0.182', 'B-cells (Lung)': '-0.197', 'Alpha cells': '0.374', 'Beta cells': '0.172', 'Prostate glandular cells': '0.093', 'Prostate basal glandular cells': '0.400', 'Urothelial cells': '0.283', 'Keratinocyte (other)': '0.597', 'Keratinocyte (granular)': '-0.067', 'Hair cortex cells': '-0.039', 'Inner root sheath cells': '-0.007', 'Outer root sheath cells': '0.116', 'Sebaceous gland cells': '0.053', 'Eccrine sweat gland cells': '-0.248', 'Adipocytes (Skin)': '-0.383', 'Mitotic cells (Skin)': '0.447', 'Parietal cells': '-0.422', 'Chief cells': '-0.314', 'Gastric mucous cells': '-0.080', 'Gastric enteroendocrine cells': '-0.187', 'Mitotic cells (Stomach)': '0.363', 'Parafollicular cells': '0.045', 'Thyroid glandular cells': '0.117', 'Mitotic cells (Thyroid)': '0.058', 'Adrenal cortex cells': '0.509', 'Adrenal medulla cells': '-0.014', 'Mitotic cells (Adrenal gland)': '0.423', 'Minor salivary glandular cells': '0.553', 'Minor salivary gland ductal cells': '-0.053', 'Minor salivary gland basal cells': '0.505', 'Mitotic cells (Minor salivary gland)': '0.616', 'Adipocytes (Minor salivary gland)': '0.268', 'Somatotropes': '-0.284', 'Lactotropes': '-0.362', 'Gonadotropes': '0.004', 'Corticotropes': '-0.175', 'Thyrotropes': '-0.048', 'Undifferentiated cells (Pituitary gland)': '0.537', 'Mitotic cells (Spleen)': '-0.087', 'Platelets': '0.030', 'Erythrocytes': '-0.192', 'Hematopoietic stem cells': '-0.087', 'B-cells (Spleen)': '0.501', 'NK-cells (Spleen)': '0.140', 'Amygdala excitatory': '3.7', 'Cerebellar inhibitory': '6.2', 'Cge interneuron': '5.2', 'Deep-layer corticothalamic and 6b': '3.9', 'Deep-layer intratelencephalic': '4.3', 'Deep-layer near-projecting': '3.7', 'Eccentric medium spiny neuron': '3.7', 'Hippocampal ca1-3': '5.1', 'Hippocampal ca4': '5.7', 'Hippocampal dentate gyrus': '3.9', 'Lamp5-lhx6 and chandelier': '6.2', 'Lower rhombic lip': '4.4', 'Mammillary body': '4.7', 'Medium spiny neuron': '3.4', 'Mge interneuron': '5.6', 'Midbrain-derived inhibitory': '3.2', 'Miscellaneous': '4.1', 'Splatter': '4.9', 'Thalamic excitatory': '4.3', 'Upper rhombic lip': '3.5', 'Upper-layer intratelencephalic': '3.3', 'Astrocyte': '44.6', 'Bergmann glia': '33.2', 'Central nervous system macrophage': '29.3', 'Choroid plexus epithelial cell': '15.7', 'Committed oligodendrocyte precursor': '19.1', 'Ependymal cell': '8.2', 'Oligodendrocyte': '14.6', 'Oligodendrocyte precursor cell': '13.8', 'Endothelial cell': '19.0', 'Pericyte': '18.3', 'Vascular associated smooth muscle cell': '13.0', 'Fibroblast': '21.1', 'Leukocyte': '28.2', 'Basophil': '11.5', 'Eosinophil': '3.4', 'Neutrophil': '7.2', 'Classical monocyte': '18.8', 'Non-classical monocyte': '38.8', 'Intermediate monocyte': '57.9', 'T-reg': '41.2', 'GdT-cell': '13.0', 'MAIT T-cell': '47.7', 'Memory CD4 T-cell': '13.4', 'Naive CD4 T-cell': '35.3', 'Memory CD8 T-cell': '14.6', 'Naive CD8 T-cell': '33.9', 'Memory B-cell': '21.7', 'Naive B-cell': '39.1', 'Plasmacytoid DC': '77.7', 'Myeloid DC': '108.7', 'NK-cell': '34.9', 'Total PBMC': '42.1', 'Vd2 gdTCR': '50.5', 'Memory CD4 T-cell Th1\\/Th17': '29.2', 'Memory CD4 T-cell Th17': '31.4', 'Memory CD4 T-cell Th2': '32.4', 'Non-Vd2 gdTCR': '44.9', 'Memory CD4 T-cell Th1': '33.4', 'Memory CD4 T-cell TFH': '41.7', 'Terminal effector memory CD4 T-cell': '37.7', 'Central memory CD8 T-cell': '50.6', 'Effector memory CD8 T-cell': '44.8', 'Terminal effector memory CD8 T-cell': '36.8', 'Non-switched memory B-cell': '67.9', 'Plasmablast': '55.7', 'Switched memory B-cell': '69.3', 'Exhausted memory B-cell': '61.4', 'Progenitor cell': '66.7', 'Memory T-reg': '44.7', 'Naive CD4 T-cell activated': '50.4', 'Naive CD8 T-cell activated': '57.4', 'Naive T-reg': '53.9'}
1A1U, 1AIE, 1C26, 1DT7, 1GZH, 1H26, 1HS5, 1JSP, 1KZY, 1MA3, 1OLG, 1OLH, 1PES, 1PET, 1SAE, 1SAF, 1SAK, 1SAL, 1TSR, 1TUP, 1UOL, 1XQH, 1YC5, 1YCQ, 1YCR, 1YCS, 2AC0, 2ADY, 2AHI, 2ATA, 2B3G, 2BIM, 2BIN, 2BIO, 2BIP, 2BIQ, 2F1X, 2FEJ, 2FOJ, 2FOO, 2GS0, 2H1L, 2H2D, 2H2F, 2H4F, 2H4H, 2H4J, 2H59, 2J0Z, 2J10, 2J11, 2J1W, 2J1X, 2J1Y, 2J1Z, 2J20, 2J21, 2K8F, 2L14, 2LY4, 2MEJ, 2MWO, 2MWP, 2MWY, 2MZD, 2OCJ, 2PCX, 2RUK, 2VUK, 2WGX, 2X0U, 2X0V, 2X0W, 2XWR, 2YBG, 2YDR, 2Z5S, 2Z5T, 3D05, 3D06, 3D07, 3D08, 3D09, 3D0A, 3DAB, 3DAC, 3IGK, 3IGL, 3KMD, 3KZ8, 3LW1, 3OQ5, 3PDH, 3Q01, 3Q05, 3Q06, 3SAK, 3TG5, 3TS8, 3ZME, 4AGL, 4AGM, 4AGN, 4AGO, 4AGP, 4AGQ, 4BUZ, 4BV2, 4HFZ, 4HJE, 4IBQ, 4IBS, 4IBT, 4IBU, 4IBV, 4IBW, 4IBY, 4IBZ, 4IJT, 4KVP, 4LO9, 4LOE, 4LOF, 4MZI, 4MZR, 4QO1, 4RP6, 4RP7, 4X34, 4XR8, 4ZZJ, 5A7B, 5AB9, 5ABA, 5AOI, 5AOJ, 5AOK, 5AOL, 5AOM, 5BUA, 5ECG, 5G4M, 5G4N, 5G4O, 5HOU, 5HP0, 5HPD, 5LAP, 5LGY, 5MCT, 5MCU, 5MCV, 5MCW, 5MF7, 5MG7, 5MHC, 5MOC, 5O1A, 5O1B, 5O1C, 5O1D, 5O1E, 5O1F, 5O1G, 5O1H, 5O1I, 5OL0, 5UN8, 5XZC, 6FF9, 6FJ5, 6GGA, 6GGB, 6GGC, 6GGD, 6GGE, 6GGF, 6LHD, 6R5L, 6RJZ, 6RK8, 6RKI, 6RKK, 6RKM, 6RL3, 6RL4, 6RL6, 6RM5, 6RM7, 6RWH, 6RWI, 6RWS, 6RWU, 6RX2, 6RZ3, 6S39, 6S3C, 6S40, 6S9Q, 6SHZ, 6SI0, 6SI1, 6SI2, 6SI3, 6SI4, 6SIN, 6SIO, 6SIP, 6SIQ, 6SL6, 6SLV, 6T58, 6V4F, 6V4H, 6VQO, 6VR1, 6VR5, 6VRM, 6VRN, 6W51, 6XRE, 6ZNC, 7B46, 7B47, 7B48, 7B49, 7B4A, 7B4B, 7B4C, 7B4D, 7B4E, 7B4F, 7B4G, 7B4H, 7B4N, 7BWN, 7DHY, 7DHZ, 7DVD, 7EAX, 7EDS, 7EEU, 7EL4, 7NMI, 7RM4, 7V97, 7XZX, 7XZZ, 7YGI, 8A31, 8A32, 8A92, 8CG7, 8DC4, 8DC6, 8DC7, 8DC8, 8E7A, 8E7B, 8F2H, 8F2I, 8GCR, 8HLL, 8HLM, 8HLN, 8J8N, 8OXM, 8OXO, 8QWK, 8QWL, 8QWM, 8QWN, 8QWO, 8QWP, 8R1F, 8R1G, 8UQR, 8WD2, 8XP5
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0.95, 0.95, 0.98, 0.9, 0.98, 0.83, 0.78, 0.79]
[40.87, 42.37, 37.34, 41.12, 36.28, 39.25, 37.74, 35.43, 38.07, 38.7, 46.99, 46.82, 45.44, 48.46, 60.33, 52.54, 56.28, 62.33, 59.05, 65.74, 66.79, 68.31, 67.62, 70.23, 70.74, 58.72, 62.81, 57.24, 45.04, 38.19, 39.44, 33.54, 35.19, 33.9, 34.62, 34.62, 30.98, 36.77, 36.14, 33.82, 35.11, 37.0, 37.65, 35.35, 40.22, 36.67, 36.17, 45.38, 43.43, 45.47, 43.32, 41.86, 42.46, 37.48, 40.19, 39.08, 41.84, 41.57, 40.13, 45.33, 44.83, 40.61, 46.68, 41.99, 40.66, 48.37, 45.35, 40.78, 42.77, 44.99, 51.82, 46.66, 45.09, 49.92, 48.07, 49.39, 51.88, 47.88, 49.9, 52.31, 51.53, 55.41, 52.55, 57.59, 53.56, 48.88, 50.01, 52.51, 44.8, 58.58, 57.48, 58.84, 61.16, 64.5, 60.79, 87.3, 91.9, 93.67, 94.32, 93.13, 95.4, 97.18, 97.88, 97.4, 96.19, 96.67, 97.18, 96.81, 98.03, 97.53, 97.93, 96.29, 97.14, 93.15, 88.03, 89.09, 89.98, 92.31, 92.8, 87.74, 91.82, 95.69, 96.78, 97.3, 97.82, 97.98, 97.12, 95.58, 94.67, 95.91, 97.14, 98.1, 98.31, 98.5, 98.18, 98.01, 96.93, 95.45, 96.64, 97.02, 97.5, 97.23, 98.15, 97.6, 97.97, 97.91, 97.61, 96.64, 95.78, 95.83, 96.75, 96.44, 96.11, 96.41, 98.18, 98.07, 98.41, 98.38, 98.48, 98.0, 97.91, 97.3, 97.85, 96.96, 94.5, 92.99, 93.51, 93.35, 93.17, 93.17, 94.24, 95.19, 96.58, 94.61, 96.38, 96.44, 95.0, 94.74, 94.02, 92.98, 91.38, 83.44, 68.18, 69.78, 67.73, 69.29, 75.66, 81.41, 90.73, 92.74, 93.45, 93.42, 95.71, 97.01, 97.65, 96.53, 96.51, 92.67, 89.17, 89.46, 90.95, 94.56, 95.63, 96.0, 96.57, 95.27, 94.47, 93.19, 90.89, 90.66, 92.07, 93.48, 95.39, 96.54, 97.45, 97.61, 97.79, 97.71, 97.66, 97.45, 96.01, 95.46, 95.62, 94.54, 94.69, 93.84, 94.06, 93.35, 95.04, 96.63, 96.93, 97.67, 97.32, 97.96, 96.97, 97.83, 96.66, 97.08, 98.03, 98.05, 97.54, 97.24, 96.47, 93.39, 94.32, 96.83, 97.3, 96.76, 97.44, 97.88, 98.33, 98.19, 98.49, 98.41, 98.58, 98.54, 98.43, 98.32, 97.12, 96.11, 95.91, 94.03, 96.55, 97.67, 98.11, 97.99, 98.54, 98.08, 98.0, 98.3, 98.38, 98.62, 98.43, 98.6, 97.98, 97.23, 96.83, 97.83, 97.02, 96.53, 97.06, 97.21, 95.97, 95.98, 96.28, 95.87, 95.03, 93.39, 91.91, 91.08, 89.16, 80.7, 66.19, 54.71, 45.53, 49.48, 47.5, 39.17, 48.58, 45.3, 47.53, 39.52, 44.86, 46.58, 47.5, 43.75, 40.22, 48.29, 42.5, 44.9, 43.14, 44.26, 44.27, 42.59, 38.35, 47.81, 48.47, 45.67, 49.67, 50.03, 50.54, 50.85, 53.27, 70.22, 79.25, 87.32, 88.32, 91.36, 93.43, 94.53, 95.74, 96.13, 96.15, 94.94, 95.04, 95.21, 94.23, 96.83, 95.75, 95.17, 96.92, 94.59, 95.14, 95.57, 95.21, 91.98, 93.68, 92.45, 88.86, 86.47, 88.93, 87.81, 82.92, 80.11, 79.44, 65.74, 59.35, 45.38, 48.65, 36.69, 34.67, 38.46, 39.41, 38.67, 38.97, 38.67, 43.72, 39.99, 39.85, 43.24, 38.88, 46.62, 42.32, 36.07, 39.71, 36.23, 42.3, 45.0, 45.17, 44.05, 45.61, 46.83, 37.81, 49.59, 48.5, 45.24, 50.91, 45.34, 59.46, 52.4, 43.13, 50.82, 47.63]
[1.0, 0.99, 0.99, 0.97, 0.97, 0.94, 0.91, 0.96, 0.91, 0.91, 0.98, 0.88, 0.89, 0.83, 0.48, 0.91, 0.84, 0.44, 0.6, 0.59, 0.57, 0.51, 0.64, 0.76, 0.78, 0.61, 0.83, 0.92, 0.92, 0.96, 0.97, 0.94, 1.0, 0.95, 0.95, 0.95, 0.94, 0.94, 1.0, 0.99, 0.99, 1.0, 0.9, 1.0, 0.89, 0.73, 0.92, 0.8, 0.94, 0.85, 0.9, 0.93, 0.97, 0.92, 0.99, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 0.99, 1.0, 0.99, 1.0, 1.0, 1.0, 1.0, 0.99, 0.97, 0.98, 0.93, 0.95, 0.98, 0.94, 0.92, 0.93, 0.92, 0.9, 0.94, 0.89, 0.91, 0.95, 0.89, 0.95, 0.87, 0.67, 0.92, 0.72, 0.51, 0.65, 0.03, 0.88, 0.47, 0.46, 0.32, 0.41, 0.44, 0.75, 0.58, 0.45, 0.54, 0.36, 0.88, 0.21, 0.08, 0.0, 0.41, 0.17, 0.16, 0.14, 0.49, 0.89, 0.38, 0.59, 0.27, 0.53, 0.82, 0.8, 0.17, 0.37, 0.18, 0.01, 0.17, 0.0, 0.56, 0.7, 0.25, 0.38, 0.07, 0.01, 0.0, 0.0, 0.24, 0.37, 0.44, 0.46, 0.38, 0.0, 0.22, 0.0, 0.18, 0.04, 0.24, 0.2, 0.66, 0.47, 0.74, 0.09, 0.52, 0.94, 0.51, 0.06, 0.24, 0.02, 0.18, 0.01, 0.15, 0.1, 0.0, 0.01, 0.5, 0.41, 0.73, 0.88, 0.19, 0.17, 0.34, 0.32, 0.12, 0.05, 0.21, 0.04, 0.04, 0.41, 0.82, 0.17, 0.37, 0.84, 0.38, 0.82, 0.54, 0.48, 0.7, 0.75, 0.59, 0.08, 0.27, 0.37, 0.28, 0.01, 0.03, 0.08, 0.04, 0.12, 0.47, 0.95, 0.2, 0.8, 0.53, 0.17, 0.47, 0.19, 0.38, 0.45, 0.39, 0.88, 0.85, 0.22, 0.4, 0.03, 0.13, 0.06, 0.01, 0.01, 0.02, 0.31, 0.14, 0.49, 0.69, 0.35, 0.84, 0.98, 0.99, 0.48, 0.59, 0.13, 0.13, 0.45, 0.09, 0.39, 0.01, 0.11, 0.0, 0.1, 0.0, 0.24, 0.09, 0.55, 0.13, 0.8, 0.66, 0.09, 0.0, 0.54, 0.8, 0.18, 0.3, 0.01, 0.11, 0.01, 0.04, 0.0, 0.12, 0.0, 0.09, 0.27, 0.69, 0.76, 0.52, 0.53, 0.4, 0.17, 0.0, 0.15, 0.19, 0.12, 0.0, 0.09, 0.02, 0.35, 0.03, 0.08, 0.71, 0.43, 0.0, 0.01, 0.63, 0.13, 0.11, 0.43, 0.34, 0.23, 0.24, 0.21, 0.46, 0.45, 0.51, 0.35, 0.63, 0.77, 0.55, 0.5, 0.77, 0.87, 0.9, 0.91, 0.94, 0.95, 0.84, 0.98, 0.9, 0.99, 0.98, 1.0, 0.99, 1.0, 0.99, 1.0, 1.0, 1.0, 0.93, 0.96, 0.92, 0.91, 0.93, 0.89, 0.93, 0.92, 0.7, 0.69, 0.78, 0.47, 0.54, 0.67, 0.68, 0.9, 0.69, 0.93, 0.33, 0.82, 0.56, 0.78, 0.78, 0.5, 0.5, 0.38, 0.62, 0.46, 0.41, 0.69, 0.56, 0.49, 0.53, 0.52, 0.51, 0.53, 0.58, 0.67, 0.6, 0.22, 0.62, 0.59, 0.67, 0.6, 0.78, 0.81, 0.94, 0.88, 0.83, 0.94, 0.86, 0.87, 0.81, 0.81, 0.82, 0.91, 0.86, 0.94, 0.95, 1.0, 0.97, 0.99, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 0.97, 0.84, 0.97, 0.84, 0.84, 0.9, 0.83, 0.98, 1.0, 1.0, 1.0, 1.0]
RING finger
Component of the RAG complex composed of core components RAG1 and RAG2, and associated component HMGB1 or HMGB2.
RAG
null
DCAF1,RAG1 , RAG2, HMGB1 or HMGB2,
H3
mono
null
null
Homodimer
null
81.264161
0.423183
74.332875
0.582494
1,067
P15918
P15918
14671314, E3NethUbiquitome
UbiNet, UbiBrowser, 31181401
RAG1
MAASFPPTLGLSSAPDEIQHPHIKFSEWKFKLFRVRSFEKTPEEAQKEKKDSFEGKPSLEQSPAVLDKADGQKPVPTQPLLKAHPKFSKKFHDNEKARGKAIHQANLRHLCRICGNSFRADEHNRRYPVHGPVDGKTLGLLRKKEKRATSWPDLIAKVFRIDVKADVDSIHPTEFCHNCWSIMHRKFSSAPCEVYFPRNVTMEWHPHTPSCDICNTARRGLKRKSLQPNLQLSKKLKTVLDQARQARQHKRRAQARISSKDVMKKIANCSKIHLSTKLLAVDFPEHFVKSISCQICEHILADPVETNCKHVFCRVCILRCLKVMGSYCPSCRYPCFPTDLESPVKSFLSVLNSLMVKCPAKECNEEVSLEKYNHHISSHKESKEIFVHINKGGRPRQHLLSLTRRAQKHRLRELKLQVKAFADKEEGGDVKSVCMTLFLLALRARNEHRQADELEAIMQGKGSGLQPAVCLAIRVNTFLSCSQYHKMYRTVKAITGRQIFQPLHALRNAEKVLLPGYHHFEWQPPLKNVSSSTDVGIIDGLSGLSSSVDDYPVDTIAKRFRYDSALVSALMDMEEDILEGMRSQDLDDYLNGPFTVVVKESCDGMGDVSEKHGSGPVVPEKAVRFSFTIMKITIAHSSQNVKVFEEAKPNSELCCKPLCLMLADESDHETLTAILSPLIAEREAMKSSELMLELGGILRTFKFIFRGTGYDEKLVREVEGLEASGSVYICTLCDATRLEASQNLVFHSITRSHAENLERYEVWRSNPYHESVEELRDRVKGVSAKPFIETVPSIDALHCDIGNAAEFYKIFQLEIGEVYKNPNASKEERKRWQATLDKHLRKKMNLKPIMRMNGNFARKLMTKETVDAVCELIPSEERHEALRELMDLYLKMKPVWRSSCPAKECPESLCQYSFNSQRFAELLSTKFKYRYEGKITNYFHKTLAHVPEIIERDGSIGAWASEGNESGNKLFRRFRKMNARQSKCYEMEDVLKHHWLYTSKYLQKFMNAHNALKTSGFTMNPQASLGDPLGIEDSLESQDSMEF
Homo sapiens
Nucleus
Tissue enriched (lymphoid)
{'Ciliated cells': '0.4', 'Basal respiratory cells': '0.5', 'Club cells': '0.7', 'Ionocytes': '0.0', 'Mucus glandular cells': '1.2', 'Serous glandular cells': '0.2', 'Gastric mucus-secreting cells': '0.0', 'Proximal enterocytes': '3.1', 'Paneth cells': '1.6', 'Distal enterocytes': '1.3', 'Intestinal goblet cells': '0.9', 'Exocrine glandular cells': '-0.280', 'Basal prostatic cells': '0.5', 'Prostatic glandular cells': '0.7', 'Breast glandular cells': '0.213', 'Breast myoepithelial cells': '0.124', 'Glandular and luminal cells': '0.4', 'Secretory cells': '1.1', 'Basal keratinocytes': '0.2', 'Suprabasal keratinocytes': '0.2', 'Basal squamous epithelial cells': '0.2', 'Squamous epithelial cells': '0.1', 'Alveolar cells type 1': '0.237', 'Alveolar cells type 2': '-0.054', 'Salivary duct cells': '1.6', 'Ductal cells': '0.483', 'Hepatocytes': '0.459', 'Cholangiocytes': '0.0', 'Proximal tubular cells': '0.265', 'Distal tubular cells': '3.1', 'Collecting duct cells': '1.9', 'Mesothelial cells': '0.203', 'Sertoli cells': '0.384', 'Granulosa cells': '1.5', 'Enteroendocrine cells': '0.4', 'Pancreatic endocrine cells': '1.7', 'Leydig cells': '0.164', 'Excitatory neurons': '1.7', 'Inhibitory neurons': '1.7', 'Cone photoreceptor cells': '0.0', 'Rod photoreceptor cells': '1.0', 'Bipolar cells': '0.9', 'Horizontal cells': '0.6', 'Astrocytes': '0.0', 'Oligodendrocyte precursor cells': '0.9', 'Oligodendrocytes': '1.2', 'Microglial cells': '0.9', 'Muller glia cells': '0.3', 'Schwann cells': '0.108', 'Spermatogonia': '0.242', 'Spermatocytes': '0.124', 'Early spermatids': '-0.095', 'Late spermatids': '-0.269', 'Oocytes': '0.0', 'Cytotrophoblasts': '0.2', 'Syncytiotrophoblasts': '0.2', 'Extravillous trophoblasts': '0.2', 'Endothelial cells': '1.9', 'Lymphatic endothelial cells': '1.3', 'Cardiomyocytes': '0.472', 'Skeletal myocytes': '-0.156', 'Smooth muscle cells': '0.6', 'Adipocytes': '1.4', 'Melanocytes': '0.021', 'Fibroblasts': '1.2', 'Peritubular cells': '0.295', 'Endometrial stromal cells': '0.3', 'Ovarian stromal cells': '0.3', 'Undifferentiated cells': '0.6', 'T-cells': '0.4', 'B-cells': '0.1', 'Plasma cells': '0.1', 'Nk-cells': '1.2', 'Granulocytes': '0.0', 'Monocytes': '0.2', 'Macrophages': '0.3', 'Hofbauer cells': '0.4', 'Kupffer cells': '1.2', 'Dendritic cells': '1.6', 'Langerhans cells': '0.138', 'Erythroid cells': '0.028', 'Adipocytes (Subcutaneous)': '-0.012', 'Adipocytes (Visceral)': '-0.165', 'Breast glandular cells (progenitors)': '0.098', 'Adipocytes (Breast)': '-0.171', 'Colon enterocytes': '0.078', 'Colon enteroendocrine cells': '0.143', 'Enteric glia cells': '0.152', 'Mitotic cells (Colon)': '0.062', 'Mitotic cells (Heart)': '0.397', 'Podocytes': '-0.072', 'Ascending Loop of Henle cells': '0.493', 'Intercalated cells': '0.034', 'Cholangiocyte': '0.092', 'NK-cells (Liver)': '-0.014', 'Respiratory ciliated cells': '0.040', 'Mitotic cells (Lung)': '0.062', 'NK-cells (Lung)': '0.045', 'B-cells (Lung)': '-0.132', 'Alpha cells': '0.314', 'Beta cells': '0.181', 'Prostate glandular cells': '-0.031', 'Prostate basal glandular cells': '0.313', 'Urothelial cells': '0.271', 'Keratinocyte (other)': '-0.231', 'Keratinocyte (granular)': '-0.135', 'Hair cortex cells': '0.246', 'Inner root sheath cells': '0.267', 'Outer root sheath cells': '0.338', 'Sebaceous gland cells': '0.259', 'Eccrine sweat gland cells': '0.376', 'Adipocytes (Skin)': '0.350', 'Mitotic cells (Skin)': '0.274', 'Parietal cells': '0.326', 'Chief cells': '0.192', 'Gastric mucous cells': '0.372', 'Gastric enteroendocrine cells': '0.286', 'Mitotic cells (Stomach)': '0.297', 'Parafollicular cells': '0.085', 'Thyroid glandular cells': '0.450', 'Mitotic cells (Thyroid)': '-0.059', 'Adrenal cortex cells': '0.592', 'Adrenal medulla cells': '-0.035', 'Mitotic cells (Adrenal gland)': '0.350', 'Minor salivary glandular cells': '0.608', 'Minor salivary gland ductal cells': '0.535', 'Minor salivary gland basal cells': '0.042', 'Mitotic cells (Minor salivary gland)': '0.035', 'Adipocytes (Minor salivary gland)': '0.177', 'Somatotropes': '0.024', 'Lactotropes': '-0.050', 'Gonadotropes': '0.102', 'Corticotropes': '-0.195', 'Thyrotropes': '0.165', 'Undifferentiated cells (Pituitary gland)': '0.287', 'Mitotic cells (Spleen)': '-0.234', 'Platelets': '-0.151', 'Erythrocytes': '-0.166', 'Hematopoietic stem cells': '-0.265', 'B-cells (Spleen)': '0.083', 'NK-cells (Spleen)': '0.264', 'Amygdala excitatory': '0.8', 'Cerebellar inhibitory': '0.6', 'Cge interneuron': '1.1', 'Deep-layer corticothalamic and 6b': '1.3', 'Deep-layer intratelencephalic': '1.5', 'Deep-layer near-projecting': '1.6', 'Eccentric medium spiny neuron': '0.5', 'Hippocampal ca1-3': '1.3', 'Hippocampal ca4': '0.3', 'Hippocampal dentate gyrus': '0.3', 'Lamp5-lhx6 and chandelier': '1.2', 'Lower rhombic lip': '2.9', 'Mammillary body': '2.6', 'Medium spiny neuron': '0.2', 'Mge interneuron': '1.8', 'Midbrain-derived inhibitory': '1.8', 'Miscellaneous': '1.1', 'Splatter': '2.1', 'Thalamic excitatory': '2.0', 'Upper rhombic lip': '0.4', 'Upper-layer intratelencephalic': '1.1', 'Astrocyte': '0.7', 'Bergmann glia': '1.4', 'Central nervous system macrophage': '1.5', 'Choroid plexus epithelial cell': '6.8', 'Committed oligodendrocyte precursor': '0.7', 'Ependymal cell': '0.5', 'Oligodendrocyte': '1.8', 'Oligodendrocyte precursor cell': '0.4', 'Endothelial cell': '6.8', 'Pericyte': '0.3', 'Vascular associated smooth muscle cell': '2.1', 'Fibroblast': '1.5', 'Leukocyte': '2.0', 'Basophil': '0.3', 'Eosinophil': '0.0', 'Neutrophil': '0.0', 'Classical monocyte': '0.0', 'Non-classical monocyte': '0.1', 'Intermediate monocyte': '0.0', 'T-reg': '0.1', 'GdT-cell': '0.0', 'MAIT T-cell': '0.3', 'Memory CD4 T-cell': '0.0', 'Naive CD4 T-cell': '0.4', 'Memory CD8 T-cell': '0.1', 'Naive CD8 T-cell': '0.3', 'Memory B-cell': '0.0', 'Naive B-cell': '0.4', 'Plasmacytoid DC': '0.0', 'Myeloid DC': '0.0', 'NK-cell': '2.3', 'Total PBMC': '0.1', 'Vd2 gdTCR': '0.0', 'Memory CD4 T-cell Th1\\/Th17': '0.8', 'Memory CD4 T-cell Th17': '0.4', 'Memory CD4 T-cell Th2': '0.4', 'Non-Vd2 gdTCR': '0.0', 'Memory CD4 T-cell Th1': '0.6', 'Memory CD4 T-cell TFH': '0.3', 'Terminal effector memory CD4 T-cell': '0.3', 'Central memory CD8 T-cell': '0.3', 'Effector memory CD8 T-cell': '0.2', 'Terminal effector memory CD8 T-cell': '0.1', 'Non-switched memory B-cell': '0.1', 'Plasmablast': '0.0', 'Switched memory B-cell': '0.0', 'Exhausted memory B-cell': '0.6', 'Progenitor cell': '0.5', 'Memory T-reg': '0.1', 'Naive CD4 T-cell activated': '0.1', 'Naive CD8 T-cell activated': '0.1', 'Naive T-reg': '0.6'}
null
{'Adipose Tissue': 0.4057857641196013, 'Adrenal Gland': 0.8675186046511627, 'Bladder': 0.3579738095238095, 'Blood': 0.2379831011840688, 'Blood Vessel': 0.2933549932584269, 'Brain': 0.1101639227857683, 'Breast': 0.4449297167755991, 'Cervix Uteri': 0.3465005263157895, 'Colon': 0.3597065468549422, 'Esophagus': 0.2373859999999999, 'Fallopian Tube': 0.4340344444444444, 'Heart': 0.1957524343786295, 'Kidney': 0.6407348314606741, 'Liver': 0.2803746017699115, 'Lung': 0.4784568079584775, 'Muscle': 0.0852849676214196, 'Nerve': 0.2672600161550889, 'Ovary': 0.3940442222222222, 'Pancreas': 0.2423982621951219, 'Pituitary': 0.2461227561837455, 'Prostate': 0.3530606122448979, 'Salivary Gland': 0.6816697530864197, 'Skin': 0.2567115765616362, 'Small Intestine': 0.5665286096256684, 'Spleen': 2.1116, 'Stomach': 0.3458365459610028, 'Testis': 0.8320800554016621, 'Thyroid': 1.571570045941807, 'Uterus': 0.4048269718309859, 'Vagina': 0.316294358974359}
RAG1
MAASFPPTLGLSSAPDEIQHPHIKFSEWKFKLFRVRSFEKTPEEAQKEKKDSFEGKPSLEQSPAVLDKADGQKPVPTQPLLKAHPKFSKKFHDNEKARGKAIHQANLRHLCRICGNSFRADEHNRRYPVHGPVDGKTLGLLRKKEKRATSWPDLIAKVFRIDVKADVDSIHPTEFCHNCWSIMHRKFSSAPCEVYFPRNVTMEWHPHTPSCDICNTARRGLKRKSLQPNLQLSKKLKTVLDQARQARQHKRRAQARISSKDVMKKIANCSKIHLSTKLLAVDFPEHFVKSISCQICEHILADPVETNCKHVFCRVCILRCLKVMGSYCPSCRYPCFPTDLESPVKSFLSVLNSLMVKCPAKECNEEVSLEKYNHHISSHKESKEIFVHINKGGRPRQHLLSLTRRAQKHRLRELKLQVKAFADKEEGGDVKSVCMTLFLLALRARNEHRQADELEAIMQGKGSGLQPAVCLAIRVNTFLSCSQYHKMYRTVKAITGRQIFQPLHALRNAEKVLLPGYHHFEWQPPLKNVSSSTDVGIIDGLSGLSSSVDDYPVDTIAKRFRYDSALVSALMDMEEDILEGMRSQDLDDYLNGPFTVVVKESCDGMGDVSEKHGSGPVVPEKAVRFSFTIMKITIAHSSQNVKVFEEAKPNSELCCKPLCLMLADESDHETLTAILSPLIAEREAMKSSELMLELGGILRTFKFIFRGTGYDEKLVREVEGLEASGSVYICTLCDATRLEASQNLVFHSITRSHAENLERYEVWRSNPYHESVEELRDRVKGVSAKPFIETVPSIDALHCDIGNAAEFYKIFQLEIGEVYKNPNASKEERKRWQATLDKHLRKKMNLKPIMRMNGNFARKLMTKETVDAVCELIPSEERHEALRELMDLYLKMKPVWRSSCPAKECPESLCQYSFNSQRFAELLSTKFKYRYEGKITNYFHKTLAHVPEIIERDGSIGAWASEGNESGNKLFRRFRKMNARQSKCYEMEDVLKHHWLYTSKYLQKFMNAHNALKTSGFTMNPQASLGDPLGIEDSLESQDSMEF
Homo sapiens
Nucleus
Tissue enriched (lymphoid)
{'Ciliated cells': '0.4', 'Basal respiratory cells': '0.5', 'Club cells': '0.7', 'Ionocytes': '0.0', 'Mucus glandular cells': '1.2', 'Serous glandular cells': '0.2', 'Gastric mucus-secreting cells': '0.0', 'Proximal enterocytes': '3.1', 'Paneth cells': '1.6', 'Distal enterocytes': '1.3', 'Intestinal goblet cells': '0.9', 'Exocrine glandular cells': '-0.280', 'Basal prostatic cells': '0.5', 'Prostatic glandular cells': '0.7', 'Breast glandular cells': '0.213', 'Breast myoepithelial cells': '0.124', 'Glandular and luminal cells': '0.4', 'Secretory cells': '1.1', 'Basal keratinocytes': '0.2', 'Suprabasal keratinocytes': '0.2', 'Basal squamous epithelial cells': '0.2', 'Squamous epithelial cells': '0.1', 'Alveolar cells type 1': '0.237', 'Alveolar cells type 2': '-0.054', 'Salivary duct cells': '1.6', 'Ductal cells': '0.483', 'Hepatocytes': '0.459', 'Cholangiocytes': '0.0', 'Proximal tubular cells': '0.265', 'Distal tubular cells': '3.1', 'Collecting duct cells': '1.9', 'Mesothelial cells': '0.203', 'Sertoli cells': '0.384', 'Granulosa cells': '1.5', 'Enteroendocrine cells': '0.4', 'Pancreatic endocrine cells': '1.7', 'Leydig cells': '0.164', 'Excitatory neurons': '1.7', 'Inhibitory neurons': '1.7', 'Cone photoreceptor cells': '0.0', 'Rod photoreceptor cells': '1.0', 'Bipolar cells': '0.9', 'Horizontal cells': '0.6', 'Astrocytes': '0.0', 'Oligodendrocyte precursor cells': '0.9', 'Oligodendrocytes': '1.2', 'Microglial cells': '0.9', 'Muller glia cells': '0.3', 'Schwann cells': '0.108', 'Spermatogonia': '0.242', 'Spermatocytes': '0.124', 'Early spermatids': '-0.095', 'Late spermatids': '-0.269', 'Oocytes': '0.0', 'Cytotrophoblasts': '0.2', 'Syncytiotrophoblasts': '0.2', 'Extravillous trophoblasts': '0.2', 'Endothelial cells': '1.9', 'Lymphatic endothelial cells': '1.3', 'Cardiomyocytes': '0.472', 'Skeletal myocytes': '-0.156', 'Smooth muscle cells': '0.6', 'Adipocytes': '1.4', 'Melanocytes': '0.021', 'Fibroblasts': '1.2', 'Peritubular cells': '0.295', 'Endometrial stromal cells': '0.3', 'Ovarian stromal cells': '0.3', 'Undifferentiated cells': '0.6', 'T-cells': '0.4', 'B-cells': '0.1', 'Plasma cells': '0.1', 'Nk-cells': '1.2', 'Granulocytes': '0.0', 'Monocytes': '0.2', 'Macrophages': '0.3', 'Hofbauer cells': '0.4', 'Kupffer cells': '1.2', 'Dendritic cells': '1.6', 'Langerhans cells': '0.138', 'Erythroid cells': '0.028', 'Adipocytes (Subcutaneous)': '-0.012', 'Adipocytes (Visceral)': '-0.165', 'Breast glandular cells (progenitors)': '0.098', 'Adipocytes (Breast)': '-0.171', 'Colon enterocytes': '0.078', 'Colon enteroendocrine cells': '0.143', 'Enteric glia cells': '0.152', 'Mitotic cells (Colon)': '0.062', 'Mitotic cells (Heart)': '0.397', 'Podocytes': '-0.072', 'Ascending Loop of Henle cells': '0.493', 'Intercalated cells': '0.034', 'Cholangiocyte': '0.092', 'NK-cells (Liver)': '-0.014', 'Respiratory ciliated cells': '0.040', 'Mitotic cells (Lung)': '0.062', 'NK-cells (Lung)': '0.045', 'B-cells (Lung)': '-0.132', 'Alpha cells': '0.314', 'Beta cells': '0.181', 'Prostate glandular cells': '-0.031', 'Prostate basal glandular cells': '0.313', 'Urothelial cells': '0.271', 'Keratinocyte (other)': '-0.231', 'Keratinocyte (granular)': '-0.135', 'Hair cortex cells': '0.246', 'Inner root sheath cells': '0.267', 'Outer root sheath cells': '0.338', 'Sebaceous gland cells': '0.259', 'Eccrine sweat gland cells': '0.376', 'Adipocytes (Skin)': '0.350', 'Mitotic cells (Skin)': '0.274', 'Parietal cells': '0.326', 'Chief cells': '0.192', 'Gastric mucous cells': '0.372', 'Gastric enteroendocrine cells': '0.286', 'Mitotic cells (Stomach)': '0.297', 'Parafollicular cells': '0.085', 'Thyroid glandular cells': '0.450', 'Mitotic cells (Thyroid)': '-0.059', 'Adrenal cortex cells': '0.592', 'Adrenal medulla cells': '-0.035', 'Mitotic cells (Adrenal gland)': '0.350', 'Minor salivary glandular cells': '0.608', 'Minor salivary gland ductal cells': '0.535', 'Minor salivary gland basal cells': '0.042', 'Mitotic cells (Minor salivary gland)': '0.035', 'Adipocytes (Minor salivary gland)': '0.177', 'Somatotropes': '0.024', 'Lactotropes': '-0.050', 'Gonadotropes': '0.102', 'Corticotropes': '-0.195', 'Thyrotropes': '0.165', 'Undifferentiated cells (Pituitary gland)': '0.287', 'Mitotic cells (Spleen)': '-0.234', 'Platelets': '-0.151', 'Erythrocytes': '-0.166', 'Hematopoietic stem cells': '-0.265', 'B-cells (Spleen)': '0.083', 'NK-cells (Spleen)': '0.264', 'Amygdala excitatory': '0.8', 'Cerebellar inhibitory': '0.6', 'Cge interneuron': '1.1', 'Deep-layer corticothalamic and 6b': '1.3', 'Deep-layer intratelencephalic': '1.5', 'Deep-layer near-projecting': '1.6', 'Eccentric medium spiny neuron': '0.5', 'Hippocampal ca1-3': '1.3', 'Hippocampal ca4': '0.3', 'Hippocampal dentate gyrus': '0.3', 'Lamp5-lhx6 and chandelier': '1.2', 'Lower rhombic lip': '2.9', 'Mammillary body': '2.6', 'Medium spiny neuron': '0.2', 'Mge interneuron': '1.8', 'Midbrain-derived inhibitory': '1.8', 'Miscellaneous': '1.1', 'Splatter': '2.1', 'Thalamic excitatory': '2.0', 'Upper rhombic lip': '0.4', 'Upper-layer intratelencephalic': '1.1', 'Astrocyte': '0.7', 'Bergmann glia': '1.4', 'Central nervous system macrophage': '1.5', 'Choroid plexus epithelial cell': '6.8', 'Committed oligodendrocyte precursor': '0.7', 'Ependymal cell': '0.5', 'Oligodendrocyte': '1.8', 'Oligodendrocyte precursor cell': '0.4', 'Endothelial cell': '6.8', 'Pericyte': '0.3', 'Vascular associated smooth muscle cell': '2.1', 'Fibroblast': '1.5', 'Leukocyte': '2.0', 'Basophil': '0.3', 'Eosinophil': '0.0', 'Neutrophil': '0.0', 'Classical monocyte': '0.0', 'Non-classical monocyte': '0.1', 'Intermediate monocyte': '0.0', 'T-reg': '0.1', 'GdT-cell': '0.0', 'MAIT T-cell': '0.3', 'Memory CD4 T-cell': '0.0', 'Naive CD4 T-cell': '0.4', 'Memory CD8 T-cell': '0.1', 'Naive CD8 T-cell': '0.3', 'Memory B-cell': '0.0', 'Naive B-cell': '0.4', 'Plasmacytoid DC': '0.0', 'Myeloid DC': '0.0', 'NK-cell': '2.3', 'Total PBMC': '0.1', 'Vd2 gdTCR': '0.0', 'Memory CD4 T-cell Th1\\/Th17': '0.8', 'Memory CD4 T-cell Th17': '0.4', 'Memory CD4 T-cell Th2': '0.4', 'Non-Vd2 gdTCR': '0.0', 'Memory CD4 T-cell Th1': '0.6', 'Memory CD4 T-cell TFH': '0.3', 'Terminal effector memory CD4 T-cell': '0.3', 'Central memory CD8 T-cell': '0.3', 'Effector memory CD8 T-cell': '0.2', 'Terminal effector memory CD8 T-cell': '0.1', 'Non-switched memory B-cell': '0.1', 'Plasmablast': '0.0', 'Switched memory B-cell': '0.0', 'Exhausted memory B-cell': '0.6', 'Progenitor cell': '0.5', 'Memory T-reg': '0.1', 'Naive CD4 T-cell activated': '0.1', 'Naive CD8 T-cell activated': '0.1', 'Naive T-reg': '0.6'}
null
{'Adipose Tissue': 0.4057857641196013, 'Adrenal Gland': 0.8675186046511627, 'Bladder': 0.3579738095238095, 'Blood': 0.2379831011840688, 'Blood Vessel': 0.2933549932584269, 'Brain': 0.1101639227857683, 'Breast': 0.4449297167755991, 'Cervix Uteri': 0.3465005263157895, 'Colon': 0.3597065468549422, 'Esophagus': 0.2373859999999999, 'Fallopian Tube': 0.4340344444444444, 'Heart': 0.1957524343786295, 'Kidney': 0.6407348314606741, 'Liver': 0.2803746017699115, 'Lung': 0.4784568079584775, 'Muscle': 0.0852849676214196, 'Nerve': 0.2672600161550889, 'Ovary': 0.3940442222222222, 'Pancreas': 0.2423982621951219, 'Pituitary': 0.2461227561837455, 'Prostate': 0.3530606122448979, 'Salivary Gland': 0.6816697530864197, 'Skin': 0.2567115765616362, 'Small Intestine': 0.5665286096256684, 'Spleen': 2.1116, 'Stomach': 0.3458365459610028, 'Testis': 0.8320800554016621, 'Thyroid': 1.571570045941807, 'Uterus': 0.4048269718309859, 'Vagina': 0.316294358974359}
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0.95, 0.95, 0.98, 0.9, 0.98, 0.83, 0.78, 0.79]
RING finger
Component of the RAG complex composed of core components RAG1 and RAG2, and associated component HMGB1 or HMGB2.
RAG
null
DCAF1,RAG1 , RAG2, HMGB1 or HMGB2,
H3
mono
null
null
Homodimer
null
81.264161
0.423183
81.264161
0.423183
472
P15918
P52292
19118899
UbiBrowser
RAG1
MAASFPPTLGLSSAPDEIQHPHIKFSEWKFKLFRVRSFEKTPEEAQKEKKDSFEGKPSLEQSPAVLDKADGQKPVPTQPLLKAHPKFSKKFHDNEKARGKAIHQANLRHLCRICGNSFRADEHNRRYPVHGPVDGKTLGLLRKKEKRATSWPDLIAKVFRIDVKADVDSIHPTEFCHNCWSIMHRKFSSAPCEVYFPRNVTMEWHPHTPSCDICNTARRGLKRKSLQPNLQLSKKLKTVLDQARQARQHKRRAQARISSKDVMKKIANCSKIHLSTKLLAVDFPEHFVKSISCQICEHILADPVETNCKHVFCRVCILRCLKVMGSYCPSCRYPCFPTDLESPVKSFLSVLNSLMVKCPAKECNEEVSLEKYNHHISSHKESKEIFVHINKGGRPRQHLLSLTRRAQKHRLRELKLQVKAFADKEEGGDVKSVCMTLFLLALRARNEHRQADELEAIMQGKGSGLQPAVCLAIRVNTFLSCSQYHKMYRTVKAITGRQIFQPLHALRNAEKVLLPGYHHFEWQPPLKNVSSSTDVGIIDGLSGLSSSVDDYPVDTIAKRFRYDSALVSALMDMEEDILEGMRSQDLDDYLNGPFTVVVKESCDGMGDVSEKHGSGPVVPEKAVRFSFTIMKITIAHSSQNVKVFEEAKPNSELCCKPLCLMLADESDHETLTAILSPLIAEREAMKSSELMLELGGILRTFKFIFRGTGYDEKLVREVEGLEASGSVYICTLCDATRLEASQNLVFHSITRSHAENLERYEVWRSNPYHESVEELRDRVKGVSAKPFIETVPSIDALHCDIGNAAEFYKIFQLEIGEVYKNPNASKEERKRWQATLDKHLRKKMNLKPIMRMNGNFARKLMTKETVDAVCELIPSEERHEALRELMDLYLKMKPVWRSSCPAKECPESLCQYSFNSQRFAELLSTKFKYRYEGKITNYFHKTLAHVPEIIERDGSIGAWASEGNESGNKLFRRFRKMNARQSKCYEMEDVLKHHWLYTSKYLQKFMNAHNALKTSGFTMNPQASLGDPLGIEDSLESQDSMEF
Homo sapiens
Nucleus
Tissue enriched (lymphoid)
{'Ciliated cells': '0.4', 'Basal respiratory cells': '0.5', 'Club cells': '0.7', 'Ionocytes': '0.0', 'Mucus glandular cells': '1.2', 'Serous glandular cells': '0.2', 'Gastric mucus-secreting cells': '0.0', 'Proximal enterocytes': '3.1', 'Paneth cells': '1.6', 'Distal enterocytes': '1.3', 'Intestinal goblet cells': '0.9', 'Exocrine glandular cells': '-0.280', 'Basal prostatic cells': '0.5', 'Prostatic glandular cells': '0.7', 'Breast glandular cells': '0.213', 'Breast myoepithelial cells': '0.124', 'Glandular and luminal cells': '0.4', 'Secretory cells': '1.1', 'Basal keratinocytes': '0.2', 'Suprabasal keratinocytes': '0.2', 'Basal squamous epithelial cells': '0.2', 'Squamous epithelial cells': '0.1', 'Alveolar cells type 1': '0.237', 'Alveolar cells type 2': '-0.054', 'Salivary duct cells': '1.6', 'Ductal cells': '0.483', 'Hepatocytes': '0.459', 'Cholangiocytes': '0.0', 'Proximal tubular cells': '0.265', 'Distal tubular cells': '3.1', 'Collecting duct cells': '1.9', 'Mesothelial cells': '0.203', 'Sertoli cells': '0.384', 'Granulosa cells': '1.5', 'Enteroendocrine cells': '0.4', 'Pancreatic endocrine cells': '1.7', 'Leydig cells': '0.164', 'Excitatory neurons': '1.7', 'Inhibitory neurons': '1.7', 'Cone photoreceptor cells': '0.0', 'Rod photoreceptor cells': '1.0', 'Bipolar cells': '0.9', 'Horizontal cells': '0.6', 'Astrocytes': '0.0', 'Oligodendrocyte precursor cells': '0.9', 'Oligodendrocytes': '1.2', 'Microglial cells': '0.9', 'Muller glia cells': '0.3', 'Schwann cells': '0.108', 'Spermatogonia': '0.242', 'Spermatocytes': '0.124', 'Early spermatids': '-0.095', 'Late spermatids': '-0.269', 'Oocytes': '0.0', 'Cytotrophoblasts': '0.2', 'Syncytiotrophoblasts': '0.2', 'Extravillous trophoblasts': '0.2', 'Endothelial cells': '1.9', 'Lymphatic endothelial cells': '1.3', 'Cardiomyocytes': '0.472', 'Skeletal myocytes': '-0.156', 'Smooth muscle cells': '0.6', 'Adipocytes': '1.4', 'Melanocytes': '0.021', 'Fibroblasts': '1.2', 'Peritubular cells': '0.295', 'Endometrial stromal cells': '0.3', 'Ovarian stromal cells': '0.3', 'Undifferentiated cells': '0.6', 'T-cells': '0.4', 'B-cells': '0.1', 'Plasma cells': '0.1', 'Nk-cells': '1.2', 'Granulocytes': '0.0', 'Monocytes': '0.2', 'Macrophages': '0.3', 'Hofbauer cells': '0.4', 'Kupffer cells': '1.2', 'Dendritic cells': '1.6', 'Langerhans cells': '0.138', 'Erythroid cells': '0.028', 'Adipocytes (Subcutaneous)': '-0.012', 'Adipocytes (Visceral)': '-0.165', 'Breast glandular cells (progenitors)': '0.098', 'Adipocytes (Breast)': '-0.171', 'Colon enterocytes': '0.078', 'Colon enteroendocrine cells': '0.143', 'Enteric glia cells': '0.152', 'Mitotic cells (Colon)': '0.062', 'Mitotic cells (Heart)': '0.397', 'Podocytes': '-0.072', 'Ascending Loop of Henle cells': '0.493', 'Intercalated cells': '0.034', 'Cholangiocyte': '0.092', 'NK-cells (Liver)': '-0.014', 'Respiratory ciliated cells': '0.040', 'Mitotic cells (Lung)': '0.062', 'NK-cells (Lung)': '0.045', 'B-cells (Lung)': '-0.132', 'Alpha cells': '0.314', 'Beta cells': '0.181', 'Prostate glandular cells': '-0.031', 'Prostate basal glandular cells': '0.313', 'Urothelial cells': '0.271', 'Keratinocyte (other)': '-0.231', 'Keratinocyte (granular)': '-0.135', 'Hair cortex cells': '0.246', 'Inner root sheath cells': '0.267', 'Outer root sheath cells': '0.338', 'Sebaceous gland cells': '0.259', 'Eccrine sweat gland cells': '0.376', 'Adipocytes (Skin)': '0.350', 'Mitotic cells (Skin)': '0.274', 'Parietal cells': '0.326', 'Chief cells': '0.192', 'Gastric mucous cells': '0.372', 'Gastric enteroendocrine cells': '0.286', 'Mitotic cells (Stomach)': '0.297', 'Parafollicular cells': '0.085', 'Thyroid glandular cells': '0.450', 'Mitotic cells (Thyroid)': '-0.059', 'Adrenal cortex cells': '0.592', 'Adrenal medulla cells': '-0.035', 'Mitotic cells (Adrenal gland)': '0.350', 'Minor salivary glandular cells': '0.608', 'Minor salivary gland ductal cells': '0.535', 'Minor salivary gland basal cells': '0.042', 'Mitotic cells (Minor salivary gland)': '0.035', 'Adipocytes (Minor salivary gland)': '0.177', 'Somatotropes': '0.024', 'Lactotropes': '-0.050', 'Gonadotropes': '0.102', 'Corticotropes': '-0.195', 'Thyrotropes': '0.165', 'Undifferentiated cells (Pituitary gland)': '0.287', 'Mitotic cells (Spleen)': '-0.234', 'Platelets': '-0.151', 'Erythrocytes': '-0.166', 'Hematopoietic stem cells': '-0.265', 'B-cells (Spleen)': '0.083', 'NK-cells (Spleen)': '0.264', 'Amygdala excitatory': '0.8', 'Cerebellar inhibitory': '0.6', 'Cge interneuron': '1.1', 'Deep-layer corticothalamic and 6b': '1.3', 'Deep-layer intratelencephalic': '1.5', 'Deep-layer near-projecting': '1.6', 'Eccentric medium spiny neuron': '0.5', 'Hippocampal ca1-3': '1.3', 'Hippocampal ca4': '0.3', 'Hippocampal dentate gyrus': '0.3', 'Lamp5-lhx6 and chandelier': '1.2', 'Lower rhombic lip': '2.9', 'Mammillary body': '2.6', 'Medium spiny neuron': '0.2', 'Mge interneuron': '1.8', 'Midbrain-derived inhibitory': '1.8', 'Miscellaneous': '1.1', 'Splatter': '2.1', 'Thalamic excitatory': '2.0', 'Upper rhombic lip': '0.4', 'Upper-layer intratelencephalic': '1.1', 'Astrocyte': '0.7', 'Bergmann glia': '1.4', 'Central nervous system macrophage': '1.5', 'Choroid plexus epithelial cell': '6.8', 'Committed oligodendrocyte precursor': '0.7', 'Ependymal cell': '0.5', 'Oligodendrocyte': '1.8', 'Oligodendrocyte precursor cell': '0.4', 'Endothelial cell': '6.8', 'Pericyte': '0.3', 'Vascular associated smooth muscle cell': '2.1', 'Fibroblast': '1.5', 'Leukocyte': '2.0', 'Basophil': '0.3', 'Eosinophil': '0.0', 'Neutrophil': '0.0', 'Classical monocyte': '0.0', 'Non-classical monocyte': '0.1', 'Intermediate monocyte': '0.0', 'T-reg': '0.1', 'GdT-cell': '0.0', 'MAIT T-cell': '0.3', 'Memory CD4 T-cell': '0.0', 'Naive CD4 T-cell': '0.4', 'Memory CD8 T-cell': '0.1', 'Naive CD8 T-cell': '0.3', 'Memory B-cell': '0.0', 'Naive B-cell': '0.4', 'Plasmacytoid DC': '0.0', 'Myeloid DC': '0.0', 'NK-cell': '2.3', 'Total PBMC': '0.1', 'Vd2 gdTCR': '0.0', 'Memory CD4 T-cell Th1\\/Th17': '0.8', 'Memory CD4 T-cell Th17': '0.4', 'Memory CD4 T-cell Th2': '0.4', 'Non-Vd2 gdTCR': '0.0', 'Memory CD4 T-cell Th1': '0.6', 'Memory CD4 T-cell TFH': '0.3', 'Terminal effector memory CD4 T-cell': '0.3', 'Central memory CD8 T-cell': '0.3', 'Effector memory CD8 T-cell': '0.2', 'Terminal effector memory CD8 T-cell': '0.1', 'Non-switched memory B-cell': '0.1', 'Plasmablast': '0.0', 'Switched memory B-cell': '0.0', 'Exhausted memory B-cell': '0.6', 'Progenitor cell': '0.5', 'Memory T-reg': '0.1', 'Naive CD4 T-cell activated': '0.1', 'Naive CD8 T-cell activated': '0.1', 'Naive T-reg': '0.6'}
null
{'Adipose Tissue': 0.4057857641196013, 'Adrenal Gland': 0.8675186046511627, 'Bladder': 0.3579738095238095, 'Blood': 0.2379831011840688, 'Blood Vessel': 0.2933549932584269, 'Brain': 0.1101639227857683, 'Breast': 0.4449297167755991, 'Cervix Uteri': 0.3465005263157895, 'Colon': 0.3597065468549422, 'Esophagus': 0.2373859999999999, 'Fallopian Tube': 0.4340344444444444, 'Heart': 0.1957524343786295, 'Kidney': 0.6407348314606741, 'Liver': 0.2803746017699115, 'Lung': 0.4784568079584775, 'Muscle': 0.0852849676214196, 'Nerve': 0.2672600161550889, 'Ovary': 0.3940442222222222, 'Pancreas': 0.2423982621951219, 'Pituitary': 0.2461227561837455, 'Prostate': 0.3530606122448979, 'Salivary Gland': 0.6816697530864197, 'Skin': 0.2567115765616362, 'Small Intestine': 0.5665286096256684, 'Spleen': 2.1116, 'Stomach': 0.3458365459610028, 'Testis': 0.8320800554016621, 'Thyroid': 1.571570045941807, 'Uterus': 0.4048269718309859, 'Vagina': 0.316294358974359}
KPNA2
MSTNENANTPAARLHRFKNKGKDSTEMRRRRIEVNVELRKAKKDDQMLKRRNVSSFPDDATSPLQENRNNQGTVNWSVDDIVKGINSSNVENQLQATQAARKLLSREKQPPIDNIIRAGLIPKFVSFLGRTDCSPIQFESAWALTNIASGTSEQTKAVVDGGAIPAFISLLASPHAHISEQAVWALGNIAGDGSVFRDLVIKYGAVDPLLALLAVPDMSSLACGYLRNLTWTLSNLCRNKNPAPPIDAVEQILPTLVRLLHHDDPEVLADTCWAISYLTDGPNERIGMVVKTGVVPQLVKLLGASELPIVTPALRAIGNIVTGTDEQTQVVIDAGALAVFPSLLTNPKTNIQKEATWTMSNITAGRQDQIQQVVNHGLVPFLVSVLSKADFKTQKEAVWAVTNYTSGGTVEQIVYLVHCGIIEPLMNLLTAKDTKIILVILDAISNIFQAAEKLGETEKLSIMIEECGGLDKIEALQNHENESVYKASLSLIEKYFSVEEEEDQNVVPETTSEGYTFQVQDGAPGTFNF
Homo sapiens
Cytoplasm, Nucleus, Endoplasmic reticulum membrane, Golgi apparatus membrane
Tissue enhanced (testis)
{'Ciliated cells': '35.0', 'Basal respiratory cells': '76.6', 'Club cells': '31.0', 'Ionocytes': '47.9', 'Mucus glandular cells': '23.7', 'Serous glandular cells': '20.1', 'Gastric mucus-secreting cells': '31.8', 'Proximal enterocytes': '14.7', 'Paneth cells': '16.2', 'Distal enterocytes': '27.1', 'Intestinal goblet cells': '31.0', 'Exocrine glandular cells': '-0.494', 'Basal prostatic cells': '8.2', 'Prostatic glandular cells': '6.2', 'Breast glandular cells': '-0.125', 'Breast myoepithelial cells': '-0.213', 'Glandular and luminal cells': '72.8', 'Secretory cells': '24.0', 'Basal keratinocytes': '92.7', 'Suprabasal keratinocytes': '69.0', 'Basal squamous epithelial cells': '50.1', 'Squamous epithelial cells': '58.5', 'Alveolar cells type 1': '-0.149', 'Alveolar cells type 2': '0.170', 'Salivary duct cells': '31.9', 'Ductal cells': '0.600', 'Hepatocytes': '0.405', 'Cholangiocytes': '5.7', 'Proximal tubular cells': '0.314', 'Distal tubular cells': '15.4', 'Collecting duct cells': '15.6', 'Mesothelial cells': '-0.268', 'Sertoli cells': '-0.376', 'Granulosa cells': '39.7', 'Enteroendocrine cells': '28.7', 'Pancreatic endocrine cells': '50.9', 'Leydig cells': '-0.378', 'Excitatory neurons': '8.2', 'Inhibitory neurons': '6.9', 'Cone photoreceptor cells': '45.9', 'Rod photoreceptor cells': '26.3', 'Bipolar cells': '25.2', 'Horizontal cells': '23.3', 'Astrocytes': '5.9', 'Oligodendrocyte precursor cells': '6.1', 'Oligodendrocytes': '5.6', 'Microglial cells': '3.6', 'Muller glia cells': '34.7', 'Schwann cells': '0.092', 'Spermatogonia': '-0.001', 'Spermatocytes': '0.393', 'Early spermatids': '0.874', 'Late spermatids': '0.507', 'Oocytes': '430.1', 'Cytotrophoblasts': '145.6', 'Syncytiotrophoblasts': '128.0', 'Extravillous trophoblasts': '315.9', 'Endothelial cells': '38.8', 'Lymphatic endothelial cells': '28.2', 'Cardiomyocytes': '0.380', 'Skeletal myocytes': '-0.257', 'Smooth muscle cells': '39.7', 'Adipocytes': '42.3', 'Melanocytes': '0.278', 'Fibroblasts': '44.3', 'Peritubular cells': '-0.312', 'Endometrial stromal cells': '66.7', 'Ovarian stromal cells': '8.4', 'Undifferentiated cells': '93.1', 'T-cells': '81.5', 'B-cells': '41.0', 'Plasma cells': '80.3', 'Nk-cells': '58.4', 'Granulocytes': '41.8', 'Monocytes': '87.6', 'Macrophages': '63.3', 'Hofbauer cells': '107.6', 'Kupffer cells': '32.5', 'Dendritic cells': '147.8', 'Langerhans cells': '0.008', 'Erythroid cells': '-0.088', 'Adipocytes (Subcutaneous)': '0.081', 'Adipocytes (Visceral)': '0.214', 'Breast glandular cells (progenitors)': '-0.183', 'Adipocytes (Breast)': '0.305', 'Colon enterocytes': '0.201', 'Colon enteroendocrine cells': '0.127', 'Enteric glia cells': '-0.318', 'Mitotic cells (Colon)': '0.217', 'Mitotic cells (Heart)': '0.455', 'Podocytes': '-0.150', 'Ascending Loop of Henle cells': '0.301', 'Intercalated cells': '-0.108', 'Cholangiocyte': '0.373', 'NK-cells (Liver)': '-0.354', 'Respiratory ciliated cells': '-0.148', 'Mitotic cells (Lung)': '0.372', 'NK-cells (Lung)': '-0.023', 'B-cells (Lung)': '-0.014', 'Alpha cells': '0.272', 'Beta cells': '0.156', 'Prostate glandular cells': '-0.177', 'Prostate basal glandular cells': '-0.022', 'Urothelial cells': '-0.036', 'Keratinocyte (other)': '-0.099', 'Keratinocyte (granular)': '-0.191', 'Hair cortex cells': '0.375', 'Inner root sheath cells': '0.473', 'Outer root sheath cells': '0.387', 'Sebaceous gland cells': '0.223', 'Eccrine sweat gland cells': '0.106', 'Adipocytes (Skin)': '0.083', 'Mitotic cells (Skin)': '0.469', 'Parietal cells': '-0.333', 'Chief cells': '-0.281', 'Gastric mucous cells': '0.131', 'Gastric enteroendocrine cells': '-0.205', 'Mitotic cells (Stomach)': '0.618', 'Parafollicular cells': '0.036', 'Thyroid glandular cells': '0.207', 'Mitotic cells (Thyroid)': '0.122', 'Adrenal cortex cells': '0.408', 'Adrenal medulla cells': '0.190', 'Mitotic cells (Adrenal gland)': '0.452', 'Minor salivary glandular cells': '0.313', 'Minor salivary gland ductal cells': '-0.314', 'Minor salivary gland basal cells': '0.642', 'Mitotic cells (Minor salivary gland)': '0.708', 'Adipocytes (Minor salivary gland)': '0.174', 'Somatotropes': '-0.149', 'Lactotropes': '-0.020', 'Gonadotropes': '0.128', 'Corticotropes': '0.123', 'Thyrotropes': '0.088', 'Undifferentiated cells (Pituitary gland)': '0.099', 'Mitotic cells (Spleen)': '0.697', 'Platelets': '0.205', 'Erythrocytes': '0.161', 'Hematopoietic stem cells': '0.275', 'B-cells (Spleen)': '-0.036', 'NK-cells (Spleen)': '-0.236', 'Amygdala excitatory': '8.2', 'Cerebellar inhibitory': '12.2', 'Cge interneuron': '12.3', 'Deep-layer corticothalamic and 6b': '8.1', 'Deep-layer intratelencephalic': '10.2', 'Deep-layer near-projecting': '7.0', 'Eccentric medium spiny neuron': '7.2', 'Hippocampal ca1-3': '16.3', 'Hippocampal ca4': '18.6', 'Hippocampal dentate gyrus': '6.9', 'Lamp5-lhx6 and chandelier': '14.9', 'Lower rhombic lip': '10.5', 'Mammillary body': '11.0', 'Medium spiny neuron': '6.2', 'Mge interneuron': '9.0', 'Midbrain-derived inhibitory': '15.5', 'Miscellaneous': '10.8', 'Splatter': '12.3', 'Thalamic excitatory': '15.4', 'Upper rhombic lip': '7.5', 'Upper-layer intratelencephalic': '7.0', 'Astrocyte': '4.5', 'Bergmann glia': '6.7', 'Central nervous system macrophage': '9.9', 'Choroid plexus epithelial cell': '4.2', 'Committed oligodendrocyte precursor': '7.4', 'Ependymal cell': '3.6', 'Oligodendrocyte': '7.4', 'Oligodendrocyte precursor cell': '5.0', 'Endothelial cell': '9.5', 'Pericyte': '8.7', 'Vascular associated smooth muscle cell': '4.8', 'Fibroblast': '3.9', 'Leukocyte': '8.9', 'Basophil': '38.1', 'Eosinophil': '13.2', 'Neutrophil': '4.3', 'Classical monocyte': '48.4', 'Non-classical monocyte': '35.1', 'Intermediate monocyte': '72.8', 'T-reg': '35.4', 'GdT-cell': '25.4', 'MAIT T-cell': '38.3', 'Memory CD4 T-cell': '19.5', 'Naive CD4 T-cell': '35.8', 'Memory CD8 T-cell': '28.0', 'Naive CD8 T-cell': '35.6', 'Memory B-cell': '48.0', 'Naive B-cell': '21.3', 'Plasmacytoid DC': '133.2', 'Myeloid DC': '113.6', 'NK-cell': '42.1', 'Total PBMC': '64.8', 'Vd2 gdTCR': '38.2', 'Memory CD4 T-cell Th1\\/Th17': '45.5', 'Memory CD4 T-cell Th17': '54.9', 'Memory CD4 T-cell Th2': '63.2', 'Non-Vd2 gdTCR': '64.7', 'Memory CD4 T-cell Th1': '50.6', 'Memory CD4 T-cell TFH': '51.6', 'Terminal effector memory CD4 T-cell': '33.6', 'Central memory CD8 T-cell': '27.0', 'Effector memory CD8 T-cell': '53.4', 'Terminal effector memory CD8 T-cell': '49.0', 'Non-switched memory B-cell': '38.9', 'Plasmablast': '207.2', 'Switched memory B-cell': '66.6', 'Exhausted memory B-cell': '51.6', 'Progenitor cell': '41.8', 'Memory T-reg': '46.0', 'Naive CD4 T-cell activated': '191.5', 'Naive CD8 T-cell activated': '176.0', 'Naive T-reg': '25.6'}
1EFX, 1QGK, 1QGR, 3FEX, 3FEY, 3WPT, 4E4V, 4WV6, 5H43, 7CRU, 7N8J, 7N9H, 8FZK, 8GCN
{'Adipose Tissue': 22.211281561461796, 'Adrenal Gland': 16.834344961240312, 'Bladder': 17.868809523809524, 'Blood': 45.72397631862218, 'Blood Vessel': 18.637334082397004, 'Brain': 16.04545041635125, 'Breast': 19.09448148148148, 'Cervix Uteri': 17.316157894736843, 'Colon': 19.71826059050064, 'Esophagus': 27.90949480968858, 'Fallopian Tube': 18.501777777777775, 'Heart': 11.490348780487803, 'Kidney': 10.988438202247192, 'Liver': 9.922061946902655, 'Lung': 27.76079238754325, 'Muscle': 8.753529265255292, 'Nerve': 19.745284329563813, 'Ovary': 10.556794444444444, 'Pancreas': 4.665703048780488, 'Pituitary': 22.54773851590106, 'Prostate': 12.481269387755102, 'Salivary Gland': 18.536043209876546, 'Skin': 63.451149253731344, 'Small Intestine': 26.79354010695187, 'Spleen': 35.69039834024896, 'Stomach': 19.68294150417827, 'Testis': 232.27573407202215, 'Thyroid': 18.361797856049005, 'Uterus': 21.395838028169013, 'Vagina': 25.19246794871795}
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[1.0, 0.99, 0.87, 0.89, 0.88, 0.77, 0.85, 0.75, 0.49, 0.71, 0.63, 0.46, 0.66, 0.76, 0.88, 0.87, 0.85, 0.92, 0.94, 0.96, 0.82, 0.53, 0.56, 0.32, 0.59, 0.33, 0.24, 0.17, 0.5, 0.61, 0.07, 0.58, 0.58, 0.26, 0.17, 0.38, 0.59, 0.57, 0.37, 0.73, 0.79, 0.7, 0.58, 0.83, 0.61, 0.71, 0.4, 0.34, 0.17, 0.32, 0.31, 0.35, 0.49, 0.18, 0.91, 0.68, 0.67, 0.76, 0.66, 0.18, 0.59, 0.07, 0.56, 0.35, 0.88, 0.32, 0.78, 0.87, 0.75, 0.91, 0.87, 0.71, 0.69, 0.68, 0.75, 0.29, 0.47, 0.2, 0.66, 0.38, 0.0, 0.24, 0.67, 0.09, 0.01, 0.57, 0.24, 0.92, 0.5, 0.34, 0.53, 0.39, 0.12, 0.17, 0.39, 0.0, 0.0, 0.24, 0.15, 0.0, 0.01, 0.3, 0.16, 0.0, 0.02, 0.37, 0.5, 0.88, 0.89, 0.14, 0.22, 0.05, 0.5, 0.39, 0.0, 0.24, 0.76, 0.34, 0.5, 0.02, 0.06, 0.61, 0.41, 0.0, 0.13, 0.53, 0.05, 0.03, 0.65, 0.25, 0.77, 0.73, 0.15, 0.23, 0.3, 0.0, 0.05, 0.04, 0.04, 0.0, 0.0, 0.05, 0.0, 0.0, 0.01, 0.0, 0.0, 0.01, 0.15, 0.29, 0.44, 0.32, 0.73, 0.11, 0.0, 0.47, 0.2, 0.0, 0.15, 0.66, 0.27, 0.36, 0.0, 0.0, 0.4, 0.2, 0.0, 0.13, 0.65, 0.04, 0.03, 0.82, 0.22, 0.94, 0.41, 0.54, 0.26, 0.0, 0.02, 0.25, 0.07, 0.0, 0.0, 0.15, 0.01, 0.0, 0.0, 0.0, 0.0, 0.01, 0.02, 0.12, 0.16, 0.15, 0.82, 0.13, 0.0, 0.32, 0.29, 0.0, 0.13, 0.83, 0.51, 0.4, 0.01, 0.04, 0.62, 0.27, 0.0, 0.11, 0.57, 0.2, 0.02, 0.68, 0.3, 0.91, 0.55, 0.04, 0.62, 0.71, 0.2, 0.64, 0.45, 0.4, 0.11, 0.03, 0.26, 0.12, 0.0, 0.0, 0.01, 0.01, 0.01, 0.02, 0.0, 0.02, 0.02, 0.16, 0.2, 0.46, 0.86, 0.58, 0.49, 0.05, 0.41, 0.47, 0.73, 0.09, 0.05, 0.55, 0.38, 0.02, 0.04, 0.6, 0.16, 0.0, 0.22, 0.34, 0.0, 0.0, 0.59, 0.2, 0.86, 0.12, 0.43, 0.46, 0.01, 0.08, 0.11, 0.11, 0.0, 0.0, 0.3, 0.0, 0.0, 0.03, 0.21, 0.06, 0.01, 0.22, 0.53, 0.59, 0.38, 0.73, 0.18, 0.0, 0.15, 0.19, 0.02, 0.18, 0.85, 0.35, 0.58, 0.01, 0.01, 0.57, 0.14, 0.0, 0.08, 0.72, 0.08, 0.02, 0.64, 0.28, 0.97, 0.48, 0.35, 0.64, 0.04, 0.05, 0.38, 0.01, 0.0, 0.0, 0.35, 0.0, 0.0, 0.0, 0.03, 0.0, 0.01, 0.33, 0.06, 0.3, 0.17, 0.64, 0.12, 0.0, 0.21, 0.36, 0.01, 0.08, 0.7, 0.25, 0.37, 0.01, 0.02, 0.63, 0.18, 0.0, 0.26, 0.56, 0.03, 0.02, 0.59, 0.26, 0.91, 0.57, 0.53, 0.68, 0.04, 0.16, 0.28, 0.16, 0.0, 0.0, 0.04, 0.01, 0.0, 0.0, 0.09, 0.01, 0.0, 0.12, 0.16, 0.33, 0.46, 0.47, 0.0, 0.0, 0.37, 0.34, 0.0, 0.17, 0.65, 0.37, 0.31, 0.0, 0.02, 0.45, 0.29, 0.05, 0.09, 0.44, 0.02, 0.01, 0.52, 0.88, 0.2, 0.38, 0.39, 0.58, 0.0, 0.13, 0.23, 0.12, 0.0, 0.0, 0.19, 0.0, 0.01, 0.06, 0.08, 0.01, 0.05, 0.28, 0.26, 0.22, 0.31, 0.23, 0.79, 0.04, 0.05, 0.32, 0.35, 0.04, 0.22, 0.72, 0.23, 0.41, 0.0, 0.09, 0.59, 0.08, 0.0, 0.0, 0.44, 0.1, 0.04, 0.67, 0.18, 0.94, 0.23, 0.28, 0.54, 0.05, 0.01, 0.34, 0.11, 0.0, 0.03, 0.36, 0.0, 0.02, 0.28, 0.09, 0.03, 0.01, 0.38, 0.05, 0.1, 0.4, 0.74, 0.52, 0.71, 0.45, 0.28, 0.75, 0.51, 0.07, 0.08, 0.44, 0.32, 0.01, 0.58, 0.75, 0.24, 0.15, 0.0, 0.15, 0.66, 0.23, 0.0, 0.44, 0.55, 0.06, 0.31, 0.83, 0.27, 0.97, 0.37, 0.6, 0.53, 0.0, 0.4, 0.58, 0.3, 0.0, 0.24, 0.5, 0.05, 0.12, 0.62, 0.72, 0.21, 0.19, 0.53, 0.83, 0.89, 0.83, 0.89, 0.76, 0.58, 0.77, 0.84, 0.74, 0.82, 0.24, 0.71, 0.7, 0.57, 1.0, 0.96, 0.43, 0.71, 0.51, 0.73, 0.85, 0.85, 0.92, 0.9, 0.9, 0.95, 0.97, 0.82, 0.96, 0.95, 0.99, 0.99]
RING finger
Component of the RAG complex composed of core components RAG1 and RAG2, and associated component HMGB1 or HMGB2.
RAG
null
DCAF1,RAG1 , RAG2, HMGB1 or HMGB2,
H3
mono
null
null
Homodimer
null
81.264161
0.423183
86.511493
0.33828
1,451
P15918
P52294
19118899, E3NethUbiquitome
UbiNet, UbiBrowser, 31181401
RAG1
MAASFPPTLGLSSAPDEIQHPHIKFSEWKFKLFRVRSFEKTPEEAQKEKKDSFEGKPSLEQSPAVLDKADGQKPVPTQPLLKAHPKFSKKFHDNEKARGKAIHQANLRHLCRICGNSFRADEHNRRYPVHGPVDGKTLGLLRKKEKRATSWPDLIAKVFRIDVKADVDSIHPTEFCHNCWSIMHRKFSSAPCEVYFPRNVTMEWHPHTPSCDICNTARRGLKRKSLQPNLQLSKKLKTVLDQARQARQHKRRAQARISSKDVMKKIANCSKIHLSTKLLAVDFPEHFVKSISCQICEHILADPVETNCKHVFCRVCILRCLKVMGSYCPSCRYPCFPTDLESPVKSFLSVLNSLMVKCPAKECNEEVSLEKYNHHISSHKESKEIFVHINKGGRPRQHLLSLTRRAQKHRLRELKLQVKAFADKEEGGDVKSVCMTLFLLALRARNEHRQADELEAIMQGKGSGLQPAVCLAIRVNTFLSCSQYHKMYRTVKAITGRQIFQPLHALRNAEKVLLPGYHHFEWQPPLKNVSSSTDVGIIDGLSGLSSSVDDYPVDTIAKRFRYDSALVSALMDMEEDILEGMRSQDLDDYLNGPFTVVVKESCDGMGDVSEKHGSGPVVPEKAVRFSFTIMKITIAHSSQNVKVFEEAKPNSELCCKPLCLMLADESDHETLTAILSPLIAEREAMKSSELMLELGGILRTFKFIFRGTGYDEKLVREVEGLEASGSVYICTLCDATRLEASQNLVFHSITRSHAENLERYEVWRSNPYHESVEELRDRVKGVSAKPFIETVPSIDALHCDIGNAAEFYKIFQLEIGEVYKNPNASKEERKRWQATLDKHLRKKMNLKPIMRMNGNFARKLMTKETVDAVCELIPSEERHEALRELMDLYLKMKPVWRSSCPAKECPESLCQYSFNSQRFAELLSTKFKYRYEGKITNYFHKTLAHVPEIIERDGSIGAWASEGNESGNKLFRRFRKMNARQSKCYEMEDVLKHHWLYTSKYLQKFMNAHNALKTSGFTMNPQASLGDPLGIEDSLESQDSMEF
Homo sapiens
Nucleus
Tissue enriched (lymphoid)
{'Ciliated cells': '0.4', 'Basal respiratory cells': '0.5', 'Club cells': '0.7', 'Ionocytes': '0.0', 'Mucus glandular cells': '1.2', 'Serous glandular cells': '0.2', 'Gastric mucus-secreting cells': '0.0', 'Proximal enterocytes': '3.1', 'Paneth cells': '1.6', 'Distal enterocytes': '1.3', 'Intestinal goblet cells': '0.9', 'Exocrine glandular cells': '-0.280', 'Basal prostatic cells': '0.5', 'Prostatic glandular cells': '0.7', 'Breast glandular cells': '0.213', 'Breast myoepithelial cells': '0.124', 'Glandular and luminal cells': '0.4', 'Secretory cells': '1.1', 'Basal keratinocytes': '0.2', 'Suprabasal keratinocytes': '0.2', 'Basal squamous epithelial cells': '0.2', 'Squamous epithelial cells': '0.1', 'Alveolar cells type 1': '0.237', 'Alveolar cells type 2': '-0.054', 'Salivary duct cells': '1.6', 'Ductal cells': '0.483', 'Hepatocytes': '0.459', 'Cholangiocytes': '0.0', 'Proximal tubular cells': '0.265', 'Distal tubular cells': '3.1', 'Collecting duct cells': '1.9', 'Mesothelial cells': '0.203', 'Sertoli cells': '0.384', 'Granulosa cells': '1.5', 'Enteroendocrine cells': '0.4', 'Pancreatic endocrine cells': '1.7', 'Leydig cells': '0.164', 'Excitatory neurons': '1.7', 'Inhibitory neurons': '1.7', 'Cone photoreceptor cells': '0.0', 'Rod photoreceptor cells': '1.0', 'Bipolar cells': '0.9', 'Horizontal cells': '0.6', 'Astrocytes': '0.0', 'Oligodendrocyte precursor cells': '0.9', 'Oligodendrocytes': '1.2', 'Microglial cells': '0.9', 'Muller glia cells': '0.3', 'Schwann cells': '0.108', 'Spermatogonia': '0.242', 'Spermatocytes': '0.124', 'Early spermatids': '-0.095', 'Late spermatids': '-0.269', 'Oocytes': '0.0', 'Cytotrophoblasts': '0.2', 'Syncytiotrophoblasts': '0.2', 'Extravillous trophoblasts': '0.2', 'Endothelial cells': '1.9', 'Lymphatic endothelial cells': '1.3', 'Cardiomyocytes': '0.472', 'Skeletal myocytes': '-0.156', 'Smooth muscle cells': '0.6', 'Adipocytes': '1.4', 'Melanocytes': '0.021', 'Fibroblasts': '1.2', 'Peritubular cells': '0.295', 'Endometrial stromal cells': '0.3', 'Ovarian stromal cells': '0.3', 'Undifferentiated cells': '0.6', 'T-cells': '0.4', 'B-cells': '0.1', 'Plasma cells': '0.1', 'Nk-cells': '1.2', 'Granulocytes': '0.0', 'Monocytes': '0.2', 'Macrophages': '0.3', 'Hofbauer cells': '0.4', 'Kupffer cells': '1.2', 'Dendritic cells': '1.6', 'Langerhans cells': '0.138', 'Erythroid cells': '0.028', 'Adipocytes (Subcutaneous)': '-0.012', 'Adipocytes (Visceral)': '-0.165', 'Breast glandular cells (progenitors)': '0.098', 'Adipocytes (Breast)': '-0.171', 'Colon enterocytes': '0.078', 'Colon enteroendocrine cells': '0.143', 'Enteric glia cells': '0.152', 'Mitotic cells (Colon)': '0.062', 'Mitotic cells (Heart)': '0.397', 'Podocytes': '-0.072', 'Ascending Loop of Henle cells': '0.493', 'Intercalated cells': '0.034', 'Cholangiocyte': '0.092', 'NK-cells (Liver)': '-0.014', 'Respiratory ciliated cells': '0.040', 'Mitotic cells (Lung)': '0.062', 'NK-cells (Lung)': '0.045', 'B-cells (Lung)': '-0.132', 'Alpha cells': '0.314', 'Beta cells': '0.181', 'Prostate glandular cells': '-0.031', 'Prostate basal glandular cells': '0.313', 'Urothelial cells': '0.271', 'Keratinocyte (other)': '-0.231', 'Keratinocyte (granular)': '-0.135', 'Hair cortex cells': '0.246', 'Inner root sheath cells': '0.267', 'Outer root sheath cells': '0.338', 'Sebaceous gland cells': '0.259', 'Eccrine sweat gland cells': '0.376', 'Adipocytes (Skin)': '0.350', 'Mitotic cells (Skin)': '0.274', 'Parietal cells': '0.326', 'Chief cells': '0.192', 'Gastric mucous cells': '0.372', 'Gastric enteroendocrine cells': '0.286', 'Mitotic cells (Stomach)': '0.297', 'Parafollicular cells': '0.085', 'Thyroid glandular cells': '0.450', 'Mitotic cells (Thyroid)': '-0.059', 'Adrenal cortex cells': '0.592', 'Adrenal medulla cells': '-0.035', 'Mitotic cells (Adrenal gland)': '0.350', 'Minor salivary glandular cells': '0.608', 'Minor salivary gland ductal cells': '0.535', 'Minor salivary gland basal cells': '0.042', 'Mitotic cells (Minor salivary gland)': '0.035', 'Adipocytes (Minor salivary gland)': '0.177', 'Somatotropes': '0.024', 'Lactotropes': '-0.050', 'Gonadotropes': '0.102', 'Corticotropes': '-0.195', 'Thyrotropes': '0.165', 'Undifferentiated cells (Pituitary gland)': '0.287', 'Mitotic cells (Spleen)': '-0.234', 'Platelets': '-0.151', 'Erythrocytes': '-0.166', 'Hematopoietic stem cells': '-0.265', 'B-cells (Spleen)': '0.083', 'NK-cells (Spleen)': '0.264', 'Amygdala excitatory': '0.8', 'Cerebellar inhibitory': '0.6', 'Cge interneuron': '1.1', 'Deep-layer corticothalamic and 6b': '1.3', 'Deep-layer intratelencephalic': '1.5', 'Deep-layer near-projecting': '1.6', 'Eccentric medium spiny neuron': '0.5', 'Hippocampal ca1-3': '1.3', 'Hippocampal ca4': '0.3', 'Hippocampal dentate gyrus': '0.3', 'Lamp5-lhx6 and chandelier': '1.2', 'Lower rhombic lip': '2.9', 'Mammillary body': '2.6', 'Medium spiny neuron': '0.2', 'Mge interneuron': '1.8', 'Midbrain-derived inhibitory': '1.8', 'Miscellaneous': '1.1', 'Splatter': '2.1', 'Thalamic excitatory': '2.0', 'Upper rhombic lip': '0.4', 'Upper-layer intratelencephalic': '1.1', 'Astrocyte': '0.7', 'Bergmann glia': '1.4', 'Central nervous system macrophage': '1.5', 'Choroid plexus epithelial cell': '6.8', 'Committed oligodendrocyte precursor': '0.7', 'Ependymal cell': '0.5', 'Oligodendrocyte': '1.8', 'Oligodendrocyte precursor cell': '0.4', 'Endothelial cell': '6.8', 'Pericyte': '0.3', 'Vascular associated smooth muscle cell': '2.1', 'Fibroblast': '1.5', 'Leukocyte': '2.0', 'Basophil': '0.3', 'Eosinophil': '0.0', 'Neutrophil': '0.0', 'Classical monocyte': '0.0', 'Non-classical monocyte': '0.1', 'Intermediate monocyte': '0.0', 'T-reg': '0.1', 'GdT-cell': '0.0', 'MAIT T-cell': '0.3', 'Memory CD4 T-cell': '0.0', 'Naive CD4 T-cell': '0.4', 'Memory CD8 T-cell': '0.1', 'Naive CD8 T-cell': '0.3', 'Memory B-cell': '0.0', 'Naive B-cell': '0.4', 'Plasmacytoid DC': '0.0', 'Myeloid DC': '0.0', 'NK-cell': '2.3', 'Total PBMC': '0.1', 'Vd2 gdTCR': '0.0', 'Memory CD4 T-cell Th1\\/Th17': '0.8', 'Memory CD4 T-cell Th17': '0.4', 'Memory CD4 T-cell Th2': '0.4', 'Non-Vd2 gdTCR': '0.0', 'Memory CD4 T-cell Th1': '0.6', 'Memory CD4 T-cell TFH': '0.3', 'Terminal effector memory CD4 T-cell': '0.3', 'Central memory CD8 T-cell': '0.3', 'Effector memory CD8 T-cell': '0.2', 'Terminal effector memory CD8 T-cell': '0.1', 'Non-switched memory B-cell': '0.1', 'Plasmablast': '0.0', 'Switched memory B-cell': '0.0', 'Exhausted memory B-cell': '0.6', 'Progenitor cell': '0.5', 'Memory T-reg': '0.1', 'Naive CD4 T-cell activated': '0.1', 'Naive CD8 T-cell activated': '0.1', 'Naive T-reg': '0.6'}
null
{'Adipose Tissue': 0.4057857641196013, 'Adrenal Gland': 0.8675186046511627, 'Bladder': 0.3579738095238095, 'Blood': 0.2379831011840688, 'Blood Vessel': 0.2933549932584269, 'Brain': 0.1101639227857683, 'Breast': 0.4449297167755991, 'Cervix Uteri': 0.3465005263157895, 'Colon': 0.3597065468549422, 'Esophagus': 0.2373859999999999, 'Fallopian Tube': 0.4340344444444444, 'Heart': 0.1957524343786295, 'Kidney': 0.6407348314606741, 'Liver': 0.2803746017699115, 'Lung': 0.4784568079584775, 'Muscle': 0.0852849676214196, 'Nerve': 0.2672600161550889, 'Ovary': 0.3940442222222222, 'Pancreas': 0.2423982621951219, 'Pituitary': 0.2461227561837455, 'Prostate': 0.3530606122448979, 'Salivary Gland': 0.6816697530864197, 'Skin': 0.2567115765616362, 'Small Intestine': 0.5665286096256684, 'Spleen': 2.1116, 'Stomach': 0.3458365459610028, 'Testis': 0.8320800554016621, 'Thyroid': 1.571570045941807, 'Uterus': 0.4048269718309859, 'Vagina': 0.316294358974359}
KPNA1
MTTPGKENFRLKSYKNKSLNPDEMRRRREEEGLQLRKQKREEQLFKRRNVATAEEETEEEVMSDGGFHEAQISNMEMAPGGVITSDMIEMIFSKSPEQQLSATQKFRKLLSKEPNPPIDEVISTPGVVARFVEFLKRKENCTLQFESAWVLTNIASGNSLQTRIVIQAGAVPIFIELLSSEFEDVQEQAVWALGNIAGDSTMCRDYVLDCNILPPLLQLFSKQNRLTMTRNAVWALSNLCRGKSPPPEFAKVSPCLNVLSWLLFVSDTDVLADACWALSYLSDGPNDKIQAVIDAGVCRRLVELLMHNDYKVVSPALRAVGNIVTGDDIQTQVILNCSALQSLLHLLSSPKESIKKEACWTISNITAGNRAQIQTVIDANIFPALISILQTAEFRTRKEAAWAITNATSGGSAEQIKYLVELGCIKPLCDLLTVMDSKIVQVALNGLENILRLGEQEAKRNGTGINPYCALIEEAYGLDKIEFLQSHENQEIYQKAFDLIEHYFGTEDEDSSIAPQVDLNQQQYIFQQCEAPMEGFQL
Homo sapiens
Cytoplasm, Nucleus
Low tissue specificity
{'Ciliated cells': '28.9', 'Basal respiratory cells': '15.0', 'Club cells': '17.9', 'Ionocytes': '17.3', 'Mucus glandular cells': '20.1', 'Serous glandular cells': '14.7', 'Gastric mucus-secreting cells': '19.5', 'Proximal enterocytes': '17.4', 'Paneth cells': '17.2', 'Distal enterocytes': '14.6', 'Intestinal goblet cells': '19.5', 'Exocrine glandular cells': '-0.621', 'Basal prostatic cells': '24.3', 'Prostatic glandular cells': '28.8', 'Breast glandular cells': '0.173', 'Breast myoepithelial cells': '0.107', 'Glandular and luminal cells': '24.1', 'Secretory cells': '18.9', 'Basal keratinocytes': '33.9', 'Suprabasal keratinocytes': '38.9', 'Basal squamous epithelial cells': '23.9', 'Squamous epithelial cells': '26.8', 'Alveolar cells type 1': '0.214', 'Alveolar cells type 2': '-0.264', 'Salivary duct cells': '18.8', 'Ductal cells': '0.604', 'Hepatocytes': '0.488', 'Cholangiocytes': '13.4', 'Proximal tubular cells': '0.158', 'Distal tubular cells': '24.6', 'Collecting duct cells': '19.4', 'Mesothelial cells': '0.048', 'Sertoli cells': '0.437', 'Granulosa cells': '8.0', 'Enteroendocrine cells': '19.4', 'Pancreatic endocrine cells': '22.1', 'Leydig cells': '0.428', 'Excitatory neurons': '103.6', 'Inhibitory neurons': '78.3', 'Cone photoreceptor cells': '32.3', 'Rod photoreceptor cells': '47.6', 'Bipolar cells': '30.1', 'Horizontal cells': '12.6', 'Astrocytes': '50.8', 'Oligodendrocyte precursor cells': '56.1', 'Oligodendrocytes': '85.4', 'Microglial cells': '59.0', 'Muller glia cells': '20.0', 'Schwann cells': '0.082', 'Spermatogonia': '0.458', 'Spermatocytes': '0.447', 'Early spermatids': '0.041', 'Late spermatids': '-0.431', 'Oocytes': '4.4', 'Cytotrophoblasts': '20.9', 'Syncytiotrophoblasts': '29.5', 'Extravillous trophoblasts': '26.6', 'Endothelial cells': '25.0', 'Lymphatic endothelial cells': '21.1', 'Cardiomyocytes': '0.631', 'Skeletal myocytes': '-0.224', 'Smooth muscle cells': '24.4', 'Adipocytes': '26.5', 'Melanocytes': '0.107', 'Fibroblasts': '23.5', 'Peritubular cells': '0.406', 'Endometrial stromal cells': '23.9', 'Ovarian stromal cells': '9.9', 'Undifferentiated cells': '11.0', 'T-cells': '30.3', 'B-cells': '30.7', 'Plasma cells': '27.8', 'Nk-cells': '33.7', 'Granulocytes': '32.9', 'Monocytes': '43.6', 'Macrophages': '29.2', 'Hofbauer cells': '21.3', 'Kupffer cells': '26.0', 'Dendritic cells': '28.9', 'Langerhans cells': '0.128', 'Erythroid cells': '-0.137', 'Adipocytes (Subcutaneous)': '0.179', 'Adipocytes (Visceral)': '-0.031', 'Breast glandular cells (progenitors)': '-0.002', 'Adipocytes (Breast)': '-0.030', 'Colon enterocytes': '-0.139', 'Colon enteroendocrine cells': '0.155', 'Enteric glia cells': '-0.224', 'Mitotic cells (Colon)': '-0.121', 'Mitotic cells (Heart)': '0.503', 'Podocytes': '-0.113', 'Ascending Loop of Henle cells': '0.382', 'Intercalated cells': '-0.084', 'Cholangiocyte': '0.233', 'NK-cells (Liver)': '-0.269', 'Respiratory ciliated cells': '0.030', 'Mitotic cells (Lung)': '-0.174', 'NK-cells (Lung)': '0.436', 'B-cells (Lung)': '0.181', 'Alpha cells': '0.414', 'Beta cells': '0.262', 'Prostate glandular cells': '-0.101', 'Prostate basal glandular cells': '0.162', 'Urothelial cells': '0.020', 'Keratinocyte (other)': '0.244', 'Keratinocyte (granular)': '-0.110', 'Hair cortex cells': '-0.067', 'Inner root sheath cells': '0.024', 'Outer root sheath cells': '0.063', 'Sebaceous gland cells': '0.043', 'Eccrine sweat gland cells': '-0.122', 'Adipocytes (Skin)': '-0.171', 'Mitotic cells (Skin)': '0.150', 'Parietal cells': '-0.631', 'Chief cells': '-0.554', 'Gastric mucous cells': '-0.416', 'Gastric enteroendocrine cells': '-0.432', 'Mitotic cells (Stomach)': '-0.012', 'Parafollicular cells': '0.096', 'Thyroid glandular cells': '0.232', 'Mitotic cells (Thyroid)': '-0.024', 'Adrenal cortex cells': '0.560', 'Adrenal medulla cells': '0.064', 'Mitotic cells (Adrenal gland)': '0.341', 'Minor salivary glandular cells': '0.393', 'Minor salivary gland ductal cells': '-0.048', 'Minor salivary gland basal cells': '0.465', 'Mitotic cells (Minor salivary gland)': '0.470', 'Adipocytes (Minor salivary gland)': '0.201', 'Somatotropes': '-0.081', 'Lactotropes': '-0.074', 'Gonadotropes': '0.024', 'Corticotropes': '-0.086', 'Thyrotropes': '-0.003', 'Undifferentiated cells (Pituitary gland)': '0.208', 'Mitotic cells (Spleen)': '-0.185', 'Platelets': '-0.099', 'Erythrocytes': '-0.063', 'Hematopoietic stem cells': '-0.256', 'B-cells (Spleen)': '0.395', 'NK-cells (Spleen)': '0.326', 'Amygdala excitatory': '142.4', 'Cerebellar inhibitory': '89.9', 'Cge interneuron': '104.2', 'Deep-layer corticothalamic and 6b': '130.6', 'Deep-layer intratelencephalic': '147.9', 'Deep-layer near-projecting': '110.4', 'Eccentric medium spiny neuron': '117.7', 'Hippocampal ca1-3': '149.5', 'Hippocampal ca4': '143.0', 'Hippocampal dentate gyrus': '128.3', 'Lamp5-lhx6 and chandelier': '110.2', 'Lower rhombic lip': '123.3', 'Mammillary body': '139.2', 'Medium spiny neuron': '121.2', 'Mge interneuron': '108.2', 'Midbrain-derived inhibitory': '117.9', 'Miscellaneous': '120.5', 'Splatter': '111.1', 'Thalamic excitatory': '130.0', 'Upper rhombic lip': '106.7', 'Upper-layer intratelencephalic': '147.5', 'Astrocyte': '88.9', 'Bergmann glia': '94.2', 'Central nervous system macrophage': '174.6', 'Choroid plexus epithelial cell': '120.1', 'Committed oligodendrocyte precursor': '94.7', 'Ependymal cell': '124.3', 'Oligodendrocyte': '130.9', 'Oligodendrocyte precursor cell': '103.1', 'Endothelial cell': '123.6', 'Pericyte': '111.1', 'Vascular associated smooth muscle cell': '101.7', 'Fibroblast': '105.6', 'Leukocyte': '132.1', 'Basophil': '31.8', 'Eosinophil': '18.9', 'Neutrophil': '72.2', 'Classical monocyte': '22.3', 'Non-classical monocyte': '32.1', 'Intermediate monocyte': '41.6', 'T-reg': '37.0', 'GdT-cell': '17.4', 'MAIT T-cell': '33.2', 'Memory CD4 T-cell': '15.2', 'Naive CD4 T-cell': '49.9', 'Memory CD8 T-cell': '19.3', 'Naive CD8 T-cell': '43.4', 'Memory B-cell': '15.8', 'Naive B-cell': '45.5', 'Plasmacytoid DC': '30.6', 'Myeloid DC': '38.8', 'NK-cell': '37.2', 'Total PBMC': '32.0', 'Vd2 gdTCR': '28.4', 'Memory CD4 T-cell TFH': '33.4', 'Memory CD4 T-cell Th2': '43.1', 'Memory CD4 T-cell Th17': '40.5', 'Memory CD4 T-cell Th1\\/Th17': '46.1', 'Non-Vd2 gdTCR': '32.2', 'Memory CD4 T-cell Th1': '37.1', 'Terminal effector memory CD4 T-cell': '51.3', 'Central memory CD8 T-cell': '44.8', 'Effector memory CD8 T-cell': '38.2', 'Terminal effector memory CD8 T-cell': '37.4', 'Switched memory B-cell': '30.6', 'Plasmablast': '48.4', 'Non-switched memory B-cell': '25.9', 'Exhausted memory B-cell': '34.2', 'Progenitor cell': '26.8', 'Naive CD4 T-cell activated': '83.7', 'Naive CD8 T-cell activated': '74.6', 'Memory T-reg': '31.3', 'Naive T-reg': '45.6'}
2JDQ, 3TJ3, 4B18, 6WX9
{'Adipose Tissue': 16.96626411960133, 'Adrenal Gland': 14.503023255813954, 'Bladder': 19.097619047619048, 'Blood': 11.973662325080731, 'Blood Vessel': 21.979731835205992, 'Brain': 11.23245798637396, 'Breast': 16.390477124183008, 'Cervix Uteri': 19.95263157894737, 'Colon': 16.478482670089857, 'Esophagus': 16.09025259515571, 'Fallopian Tube': 18.56, 'Heart': 8.964315911730546, 'Kidney': 7.069955056179776, 'Liver': 8.114858407079646, 'Lung': 20.074091695501732, 'Muscle': 38.468493150684935, 'Nerve': 21.93856219709208, 'Ovary': 16.641433333333335, 'Pancreas': 5.830640243902439, 'Pituitary': 15.286901060070672, 'Prostate': 16.90897142857143, 'Salivary Gland': 12.801858024691358, 'Skin': 17.74252017689331, 'Small Intestine': 14.951620320855614, 'Spleen': 15.80356846473029, 'Stomach': 11.67091364902507, 'Testis': 18.677479224376732, 'Thyroid': 18.03396784073507, 'Uterus': 21.702042253521128, 'Vagina': 17.03802564102564}
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[0.97, 0.92, 0.91, 0.92, 0.54, 0.9, 0.81, 0.69, 0.75, 0.77, 0.63, 0.78, 0.47, 0.47, 0.16, 0.47, 0.75, 0.81, 0.5, 0.35, 0.64, 0.3, 0.25, 0.36, 0.62, 0.14, 0.46, 0.63, 0.61, 0.33, 0.42, 0.37, 0.67, 0.26, 0.38, 0.77, 0.59, 0.18, 0.68, 0.74, 0.4, 0.23, 0.67, 0.63, 0.18, 0.05, 0.61, 0.36, 0.11, 0.21, 0.55, 0.44, 0.13, 0.48, 0.78, 0.48, 0.35, 0.84, 0.93, 0.82, 0.76, 0.4, 0.91, 0.93, 0.7, 0.98, 0.92, 0.9, 0.88, 0.89, 0.88, 0.49, 0.87, 0.88, 0.64, 0.89, 0.89, 0.65, 0.96, 0.88, 0.49, 0.31, 0.11, 0.37, 0.55, 0.5, 0.06, 0.3, 0.63, 0.12, 0.0, 0.46, 0.15, 0.92, 0.29, 0.41, 0.74, 0.43, 0.01, 0.22, 0.35, 0.0, 0.0, 0.34, 0.31, 0.0, 0.23, 0.53, 0.11, 0.04, 0.21, 0.41, 0.78, 0.79, 0.93, 0.3, 0.18, 0.07, 0.54, 0.32, 0.0, 0.2, 0.74, 0.16, 0.81, 0.45, 0.0, 0.07, 0.46, 0.18, 0.0, 0.04, 0.49, 0.0, 0.01, 0.62, 0.21, 0.69, 0.84, 0.25, 0.17, 0.31, 0.0, 0.02, 0.18, 0.09, 0.0, 0.0, 0.12, 0.0, 0.0, 0.01, 0.05, 0.0, 0.0, 0.16, 0.24, 0.47, 0.35, 0.53, 0.06, 0.0, 0.37, 0.3, 0.0, 0.17, 0.76, 0.32, 0.35, 0.0, 0.0, 0.41, 0.1, 0.0, 0.09, 0.63, 0.06, 0.04, 0.64, 0.17, 0.95, 0.37, 0.35, 0.23, 0.01, 0.09, 0.17, 0.04, 0.0, 0.01, 0.07, 0.01, 0.02, 0.0, 0.0, 0.0, 0.04, 0.08, 0.09, 0.39, 0.26, 0.68, 0.0, 0.01, 0.28, 0.37, 0.0, 0.08, 0.61, 0.28, 0.61, 0.02, 0.07, 0.57, 0.16, 0.02, 0.17, 0.43, 0.04, 0.1, 0.8, 0.69, 0.14, 0.95, 0.39, 0.42, 0.3, 0.02, 0.16, 0.31, 0.11, 0.01, 0.0, 0.0, 0.02, 0.01, 0.0, 0.02, 0.01, 0.03, 0.09, 0.3, 0.33, 0.66, 0.58, 0.6, 0.08, 0.57, 0.21, 0.74, 0.3, 0.02, 0.3, 0.47, 0.0, 0.06, 0.72, 0.17, 0.0, 0.18, 0.59, 0.0, 0.0, 0.66, 0.22, 0.85, 0.16, 0.28, 0.28, 0.0, 0.02, 0.06, 0.0, 0.0, 0.0, 0.31, 0.0, 0.0, 0.02, 0.26, 0.02, 0.01, 0.37, 0.51, 0.52, 0.31, 0.69, 0.22, 0.0, 0.36, 0.25, 0.0, 0.13, 0.7, 0.18, 0.61, 0.01, 0.06, 0.67, 0.24, 0.0, 0.04, 0.42, 0.02, 0.01, 0.48, 0.3, 0.9, 0.33, 0.26, 0.55, 0.0, 0.01, 0.38, 0.0, 0.0, 0.01, 0.24, 0.01, 0.0, 0.0, 0.05, 0.0, 0.0, 0.28, 0.0, 0.31, 0.13, 0.72, 0.02, 0.0, 0.36, 0.32, 0.0, 0.12, 0.67, 0.27, 0.6, 0.0, 0.09, 0.59, 0.1, 0.0, 0.23, 0.58, 0.03, 0.04, 0.76, 0.07, 0.79, 0.45, 0.23, 0.6, 0.02, 0.19, 0.32, 0.18, 0.0, 0.0, 0.12, 0.0, 0.0, 0.07, 0.15, 0.0, 0.0, 0.37, 0.03, 0.19, 0.5, 0.58, 0.01, 0.01, 0.37, 0.31, 0.0, 0.12, 0.69, 0.08, 0.53, 0.0, 0.01, 0.35, 0.24, 0.0, 0.05, 0.44, 0.08, 0.01, 0.58, 0.78, 0.23, 0.62, 0.37, 0.72, 0.0, 0.19, 0.26, 0.13, 0.0, 0.0, 0.18, 0.0, 0.0, 0.05, 0.18, 0.01, 0.03, 0.61, 0.21, 0.14, 0.21, 0.37, 0.72, 0.06, 0.08, 0.4, 0.28, 0.01, 0.11, 0.66, 0.31, 0.42, 0.0, 0.05, 0.42, 0.01, 0.0, 0.0, 0.3, 0.0, 0.03, 0.7, 0.19, 0.91, 0.3, 0.25, 0.25, 0.03, 0.0, 0.16, 0.04, 0.01, 0.0, 0.37, 0.0, 0.0, 0.2, 0.13, 0.0, 0.0, 0.4, 0.05, 0.0, 0.28, 0.56, 0.15, 0.04, 0.67, 0.75, 0.7, 0.75, 0.53, 0.72, 0.72, 0.15, 0.47, 0.06, 0.1, 0.43, 0.37, 0.0, 0.49, 0.69, 0.05, 0.62, 0.0, 0.18, 0.52, 0.16, 0.0, 0.48, 0.73, 0.02, 0.32, 0.72, 0.25, 0.94, 0.31, 0.75, 0.62, 0.0, 0.39, 0.52, 0.26, 0.0, 0.4, 0.44, 0.03, 0.17, 0.65, 0.74, 0.2, 0.18, 0.48, 0.92, 0.92, 0.93, 0.83, 0.5, 0.79, 0.82, 0.76, 0.4, 0.32, 0.58, 0.54, 0.3, 0.84, 0.92, 0.68, 0.84, 0.62, 0.65, 0.45, 0.75, 0.79, 0.92, 0.86, 0.91, 0.76, 0.85, 0.93, 0.89, 0.79, 0.92, 0.94, 0.95]
RING finger
Component of the RAG complex composed of core components RAG1 and RAG2, and associated component HMGB1 or HMGB2.
RAG
null
DCAF1,RAG1 , RAG2, HMGB1 or HMGB2,
H3
mono
null
null
Homodimer
null
81.264161
0.423183
86.439201
0.334907
1,451
P15918
Q16695
20122409
UbiNet, UbiBrowser, 31181401
RAG1
MAASFPPTLGLSSAPDEIQHPHIKFSEWKFKLFRVRSFEKTPEEAQKEKKDSFEGKPSLEQSPAVLDKADGQKPVPTQPLLKAHPKFSKKFHDNEKARGKAIHQANLRHLCRICGNSFRADEHNRRYPVHGPVDGKTLGLLRKKEKRATSWPDLIAKVFRIDVKADVDSIHPTEFCHNCWSIMHRKFSSAPCEVYFPRNVTMEWHPHTPSCDICNTARRGLKRKSLQPNLQLSKKLKTVLDQARQARQHKRRAQARISSKDVMKKIANCSKIHLSTKLLAVDFPEHFVKSISCQICEHILADPVETNCKHVFCRVCILRCLKVMGSYCPSCRYPCFPTDLESPVKSFLSVLNSLMVKCPAKECNEEVSLEKYNHHISSHKESKEIFVHINKGGRPRQHLLSLTRRAQKHRLRELKLQVKAFADKEEGGDVKSVCMTLFLLALRARNEHRQADELEAIMQGKGSGLQPAVCLAIRVNTFLSCSQYHKMYRTVKAITGRQIFQPLHALRNAEKVLLPGYHHFEWQPPLKNVSSSTDVGIIDGLSGLSSSVDDYPVDTIAKRFRYDSALVSALMDMEEDILEGMRSQDLDDYLNGPFTVVVKESCDGMGDVSEKHGSGPVVPEKAVRFSFTIMKITIAHSSQNVKVFEEAKPNSELCCKPLCLMLADESDHETLTAILSPLIAEREAMKSSELMLELGGILRTFKFIFRGTGYDEKLVREVEGLEASGSVYICTLCDATRLEASQNLVFHSITRSHAENLERYEVWRSNPYHESVEELRDRVKGVSAKPFIETVPSIDALHCDIGNAAEFYKIFQLEIGEVYKNPNASKEERKRWQATLDKHLRKKMNLKPIMRMNGNFARKLMTKETVDAVCELIPSEERHEALRELMDLYLKMKPVWRSSCPAKECPESLCQYSFNSQRFAELLSTKFKYRYEGKITNYFHKTLAHVPEIIERDGSIGAWASEGNESGNKLFRRFRKMNARQSKCYEMEDVLKHHWLYTSKYLQKFMNAHNALKTSGFTMNPQASLGDPLGIEDSLESQDSMEF
Homo sapiens
Nucleus
Tissue enriched (lymphoid)
{'Ciliated cells': '0.4', 'Basal respiratory cells': '0.5', 'Club cells': '0.7', 'Ionocytes': '0.0', 'Mucus glandular cells': '1.2', 'Serous glandular cells': '0.2', 'Gastric mucus-secreting cells': '0.0', 'Proximal enterocytes': '3.1', 'Paneth cells': '1.6', 'Distal enterocytes': '1.3', 'Intestinal goblet cells': '0.9', 'Exocrine glandular cells': '-0.280', 'Basal prostatic cells': '0.5', 'Prostatic glandular cells': '0.7', 'Breast glandular cells': '0.213', 'Breast myoepithelial cells': '0.124', 'Glandular and luminal cells': '0.4', 'Secretory cells': '1.1', 'Basal keratinocytes': '0.2', 'Suprabasal keratinocytes': '0.2', 'Basal squamous epithelial cells': '0.2', 'Squamous epithelial cells': '0.1', 'Alveolar cells type 1': '0.237', 'Alveolar cells type 2': '-0.054', 'Salivary duct cells': '1.6', 'Ductal cells': '0.483', 'Hepatocytes': '0.459', 'Cholangiocytes': '0.0', 'Proximal tubular cells': '0.265', 'Distal tubular cells': '3.1', 'Collecting duct cells': '1.9', 'Mesothelial cells': '0.203', 'Sertoli cells': '0.384', 'Granulosa cells': '1.5', 'Enteroendocrine cells': '0.4', 'Pancreatic endocrine cells': '1.7', 'Leydig cells': '0.164', 'Excitatory neurons': '1.7', 'Inhibitory neurons': '1.7', 'Cone photoreceptor cells': '0.0', 'Rod photoreceptor cells': '1.0', 'Bipolar cells': '0.9', 'Horizontal cells': '0.6', 'Astrocytes': '0.0', 'Oligodendrocyte precursor cells': '0.9', 'Oligodendrocytes': '1.2', 'Microglial cells': '0.9', 'Muller glia cells': '0.3', 'Schwann cells': '0.108', 'Spermatogonia': '0.242', 'Spermatocytes': '0.124', 'Early spermatids': '-0.095', 'Late spermatids': '-0.269', 'Oocytes': '0.0', 'Cytotrophoblasts': '0.2', 'Syncytiotrophoblasts': '0.2', 'Extravillous trophoblasts': '0.2', 'Endothelial cells': '1.9', 'Lymphatic endothelial cells': '1.3', 'Cardiomyocytes': '0.472', 'Skeletal myocytes': '-0.156', 'Smooth muscle cells': '0.6', 'Adipocytes': '1.4', 'Melanocytes': '0.021', 'Fibroblasts': '1.2', 'Peritubular cells': '0.295', 'Endometrial stromal cells': '0.3', 'Ovarian stromal cells': '0.3', 'Undifferentiated cells': '0.6', 'T-cells': '0.4', 'B-cells': '0.1', 'Plasma cells': '0.1', 'Nk-cells': '1.2', 'Granulocytes': '0.0', 'Monocytes': '0.2', 'Macrophages': '0.3', 'Hofbauer cells': '0.4', 'Kupffer cells': '1.2', 'Dendritic cells': '1.6', 'Langerhans cells': '0.138', 'Erythroid cells': '0.028', 'Adipocytes (Subcutaneous)': '-0.012', 'Adipocytes (Visceral)': '-0.165', 'Breast glandular cells (progenitors)': '0.098', 'Adipocytes (Breast)': '-0.171', 'Colon enterocytes': '0.078', 'Colon enteroendocrine cells': '0.143', 'Enteric glia cells': '0.152', 'Mitotic cells (Colon)': '0.062', 'Mitotic cells (Heart)': '0.397', 'Podocytes': '-0.072', 'Ascending Loop of Henle cells': '0.493', 'Intercalated cells': '0.034', 'Cholangiocyte': '0.092', 'NK-cells (Liver)': '-0.014', 'Respiratory ciliated cells': '0.040', 'Mitotic cells (Lung)': '0.062', 'NK-cells (Lung)': '0.045', 'B-cells (Lung)': '-0.132', 'Alpha cells': '0.314', 'Beta cells': '0.181', 'Prostate glandular cells': '-0.031', 'Prostate basal glandular cells': '0.313', 'Urothelial cells': '0.271', 'Keratinocyte (other)': '-0.231', 'Keratinocyte (granular)': '-0.135', 'Hair cortex cells': '0.246', 'Inner root sheath cells': '0.267', 'Outer root sheath cells': '0.338', 'Sebaceous gland cells': '0.259', 'Eccrine sweat gland cells': '0.376', 'Adipocytes (Skin)': '0.350', 'Mitotic cells (Skin)': '0.274', 'Parietal cells': '0.326', 'Chief cells': '0.192', 'Gastric mucous cells': '0.372', 'Gastric enteroendocrine cells': '0.286', 'Mitotic cells (Stomach)': '0.297', 'Parafollicular cells': '0.085', 'Thyroid glandular cells': '0.450', 'Mitotic cells (Thyroid)': '-0.059', 'Adrenal cortex cells': '0.592', 'Adrenal medulla cells': '-0.035', 'Mitotic cells (Adrenal gland)': '0.350', 'Minor salivary glandular cells': '0.608', 'Minor salivary gland ductal cells': '0.535', 'Minor salivary gland basal cells': '0.042', 'Mitotic cells (Minor salivary gland)': '0.035', 'Adipocytes (Minor salivary gland)': '0.177', 'Somatotropes': '0.024', 'Lactotropes': '-0.050', 'Gonadotropes': '0.102', 'Corticotropes': '-0.195', 'Thyrotropes': '0.165', 'Undifferentiated cells (Pituitary gland)': '0.287', 'Mitotic cells (Spleen)': '-0.234', 'Platelets': '-0.151', 'Erythrocytes': '-0.166', 'Hematopoietic stem cells': '-0.265', 'B-cells (Spleen)': '0.083', 'NK-cells (Spleen)': '0.264', 'Amygdala excitatory': '0.8', 'Cerebellar inhibitory': '0.6', 'Cge interneuron': '1.1', 'Deep-layer corticothalamic and 6b': '1.3', 'Deep-layer intratelencephalic': '1.5', 'Deep-layer near-projecting': '1.6', 'Eccentric medium spiny neuron': '0.5', 'Hippocampal ca1-3': '1.3', 'Hippocampal ca4': '0.3', 'Hippocampal dentate gyrus': '0.3', 'Lamp5-lhx6 and chandelier': '1.2', 'Lower rhombic lip': '2.9', 'Mammillary body': '2.6', 'Medium spiny neuron': '0.2', 'Mge interneuron': '1.8', 'Midbrain-derived inhibitory': '1.8', 'Miscellaneous': '1.1', 'Splatter': '2.1', 'Thalamic excitatory': '2.0', 'Upper rhombic lip': '0.4', 'Upper-layer intratelencephalic': '1.1', 'Astrocyte': '0.7', 'Bergmann glia': '1.4', 'Central nervous system macrophage': '1.5', 'Choroid plexus epithelial cell': '6.8', 'Committed oligodendrocyte precursor': '0.7', 'Ependymal cell': '0.5', 'Oligodendrocyte': '1.8', 'Oligodendrocyte precursor cell': '0.4', 'Endothelial cell': '6.8', 'Pericyte': '0.3', 'Vascular associated smooth muscle cell': '2.1', 'Fibroblast': '1.5', 'Leukocyte': '2.0', 'Basophil': '0.3', 'Eosinophil': '0.0', 'Neutrophil': '0.0', 'Classical monocyte': '0.0', 'Non-classical monocyte': '0.1', 'Intermediate monocyte': '0.0', 'T-reg': '0.1', 'GdT-cell': '0.0', 'MAIT T-cell': '0.3', 'Memory CD4 T-cell': '0.0', 'Naive CD4 T-cell': '0.4', 'Memory CD8 T-cell': '0.1', 'Naive CD8 T-cell': '0.3', 'Memory B-cell': '0.0', 'Naive B-cell': '0.4', 'Plasmacytoid DC': '0.0', 'Myeloid DC': '0.0', 'NK-cell': '2.3', 'Total PBMC': '0.1', 'Vd2 gdTCR': '0.0', 'Memory CD4 T-cell Th1\\/Th17': '0.8', 'Memory CD4 T-cell Th17': '0.4', 'Memory CD4 T-cell Th2': '0.4', 'Non-Vd2 gdTCR': '0.0', 'Memory CD4 T-cell Th1': '0.6', 'Memory CD4 T-cell TFH': '0.3', 'Terminal effector memory CD4 T-cell': '0.3', 'Central memory CD8 T-cell': '0.3', 'Effector memory CD8 T-cell': '0.2', 'Terminal effector memory CD8 T-cell': '0.1', 'Non-switched memory B-cell': '0.1', 'Plasmablast': '0.0', 'Switched memory B-cell': '0.0', 'Exhausted memory B-cell': '0.6', 'Progenitor cell': '0.5', 'Memory T-reg': '0.1', 'Naive CD4 T-cell activated': '0.1', 'Naive CD8 T-cell activated': '0.1', 'Naive T-reg': '0.6'}
null
{'Adipose Tissue': 0.4057857641196013, 'Adrenal Gland': 0.8675186046511627, 'Bladder': 0.3579738095238095, 'Blood': 0.2379831011840688, 'Blood Vessel': 0.2933549932584269, 'Brain': 0.1101639227857683, 'Breast': 0.4449297167755991, 'Cervix Uteri': 0.3465005263157895, 'Colon': 0.3597065468549422, 'Esophagus': 0.2373859999999999, 'Fallopian Tube': 0.4340344444444444, 'Heart': 0.1957524343786295, 'Kidney': 0.6407348314606741, 'Liver': 0.2803746017699115, 'Lung': 0.4784568079584775, 'Muscle': 0.0852849676214196, 'Nerve': 0.2672600161550889, 'Ovary': 0.3940442222222222, 'Pancreas': 0.2423982621951219, 'Pituitary': 0.2461227561837455, 'Prostate': 0.3530606122448979, 'Salivary Gland': 0.6816697530864197, 'Skin': 0.2567115765616362, 'Small Intestine': 0.5665286096256684, 'Spleen': 2.1116, 'Stomach': 0.3458365459610028, 'Testis': 0.8320800554016621, 'Thyroid': 1.571570045941807, 'Uterus': 0.4048269718309859, 'Vagina': 0.316294358974359}
H3-4
MARTKQTARKSTGGKAPRKQLATKVARKSAPATGGVKKPHRYRPGTVALREIRRYQKSTELLIRKLPFQRLMREIAQDFKTDLRFQSSAVMALQEACESYLVGLFEDTNLCVIHAKRVTIMPKDIQLARRIRGERA
Homo sapiens
Nucleus, Chromosome
Tissue enriched (testis)
{'Ciliated cells': '0.0', 'Basal respiratory cells': '0.0', 'Club cells': '0.0', 'Ionocytes': '0.0', 'Mucus glandular cells': '0.0', 'Serous glandular cells': '0.0', 'Gastric mucus-secreting cells': '0.0', 'Proximal enterocytes': '0.0', 'Paneth cells': '0.0', 'Distal enterocytes': '0.0', 'Intestinal goblet cells': '0.0', 'Exocrine glandular cells': '0.001', 'Basal prostatic cells': '0.0', 'Prostatic glandular cells': '0.0', 'Breast glandular cells': '0.203', 'Breast myoepithelial cells': '0.182', 'Glandular and luminal cells': '0.0', 'Secretory cells': '0.0', 'Basal keratinocytes': '0.0', 'Suprabasal keratinocytes': '0.0', 'Basal squamous epithelial cells': '0.0', 'Squamous epithelial cells': '0.0', 'Alveolar cells type 1': '0.086', 'Alveolar cells type 2': '0.103', 'Salivary duct cells': '0.0', 'Ductal cells': '0.088', 'Hepatocytes': '0.060', 'Cholangiocytes': '0.0', 'Proximal tubular cells': '-0.053', 'Distal tubular cells': '0.0', 'Collecting duct cells': '0.0', 'Mesothelial cells': '0.105', 'Sertoli cells': '-0.024', 'Granulosa cells': '0.0', 'Enteroendocrine cells': '0.0', 'Pancreatic endocrine cells': '0.0', 'Leydig cells': '-0.101', 'Excitatory neurons': '0.0', 'Inhibitory neurons': '0.0', 'Cone photoreceptor cells': '0.0', 'Rod photoreceptor cells': '0.0', 'Bipolar cells': '0.0', 'Horizontal cells': '0.0', 'Astrocytes': '0.0', 'Oligodendrocyte precursor cells': '0.0', 'Oligodendrocytes': '0.0', 'Microglial cells': '0.0', 'Muller glia cells': '0.0', 'Schwann cells': '0.119', 'Spermatogonia': '-0.086', 'Spermatocytes': '0.045', 'Early spermatids': '-0.038', 'Late spermatids': '0.096', 'Oocytes': '0.0', 'Cytotrophoblasts': '0.0', 'Syncytiotrophoblasts': '0.0', 'Extravillous trophoblasts': '0.0', 'Endothelial cells': '0.0', 'Lymphatic endothelial cells': '0.0', 'Cardiomyocytes': '0.119', 'Skeletal myocytes': '0.048', 'Smooth muscle cells': '0.0', 'Adipocytes': '0.0', 'Melanocytes': '0.057', 'Fibroblasts': '0.0', 'Peritubular cells': '-0.103', 'Endometrial stromal cells': '0.0', 'Ovarian stromal cells': '0.0', 'Undifferentiated cells': '0.0', 'T-cells': '0.0', 'B-cells': '0.0', 'Plasma cells': '0.0', 'Nk-cells': '0.0', 'Granulocytes': '0.0', 'Monocytes': '0.0', 'Macrophages': '0.0', 'Hofbauer cells': '0.0', 'Kupffer cells': '0.0', 'Dendritic cells': '0.0', 'Langerhans cells': '0.039', 'Erythroid cells': '-0.040', 'Adipocytes (Subcutaneous)': '-0.123', 'Adipocytes (Visceral)': '-0.056', 'Breast glandular cells (progenitors)': '0.205', 'Adipocytes (Breast)': '-0.083', 'Colon enterocytes': '0.051', 'Colon enteroendocrine cells': '-0.014', 'Enteric glia cells': '-0.001', 'Mitotic cells (Colon)': '0.031', 'Mitotic cells (Heart)': '0.103', 'Podocytes': '-0.034', 'Ascending Loop of Henle cells': '0.113', 'Intercalated cells': '-0.042', 'Cholangiocyte': '0.055', 'NK-cells (Liver)': '0.027', 'Respiratory ciliated cells': '0.037', 'Mitotic cells (Lung)': '0.039', 'NK-cells (Lung)': '-0.050', 'B-cells (Lung)': '-0.024', 'Alpha cells': '0.037', 'Beta cells': '0.034', 'Prostate glandular cells': '-0.062', 'Prostate basal glandular cells': '0.147', 'Urothelial cells': '0.162', 'Keratinocyte (other)': '0.009', 'Keratinocyte (granular)': '-0.175', 'Hair cortex cells': '0.020', 'Inner root sheath cells': '0.027', 'Outer root sheath cells': '0.101', 'Sebaceous gland cells': '-0.014', 'Eccrine sweat gland cells': '-0.015', 'Adipocytes (Skin)': '0.047', 'Mitotic cells (Skin)': '0.177', 'Parietal cells': '-0.194', 'Chief cells': '-0.222', 'Gastric mucous cells': '-0.056', 'Gastric enteroendocrine cells': '-0.151', 'Mitotic cells (Stomach)': '-0.019', 'Parafollicular cells': '0.024', 'Thyroid glandular cells': '-0.015', 'Mitotic cells (Thyroid)': '0.005', 'Adrenal cortex cells': '0.214', 'Adrenal medulla cells': '0.062', 'Mitotic cells (Adrenal gland)': '0.118', 'Minor salivary glandular cells': '0.119', 'Minor salivary gland ductal cells': '0.213', 'Minor salivary gland basal cells': '0.023', 'Mitotic cells (Minor salivary gland)': '-0.099', 'Adipocytes (Minor salivary gland)': '0.155', 'Somatotropes': '-0.252', 'Lactotropes': '-0.133', 'Gonadotropes': '0.007', 'Corticotropes': '-0.050', 'Thyrotropes': '-0.019', 'Undifferentiated cells (Pituitary gland)': '0.162', 'Mitotic cells (Spleen)': '0.051', 'Platelets': '-0.002', 'Erythrocytes': '-0.091', 'Hematopoietic stem cells': '-0.069', 'B-cells (Spleen)': '0.108', 'NK-cells (Spleen)': '0.134', 'Amygdala excitatory': '0.0', 'Cerebellar inhibitory': '0.0', 'Cge interneuron': '0.0', 'Deep-layer corticothalamic and 6b': '0.0', 'Deep-layer intratelencephalic': '0.0', 'Deep-layer near-projecting': '0.0', 'Eccentric medium spiny neuron': '0.0', 'Hippocampal ca1-3': '0.0', 'Hippocampal ca4': '0.0', 'Hippocampal dentate gyrus': '0.0', 'Lamp5-lhx6 and chandelier': '0.0', 'Lower rhombic lip': '0.0', 'Mammillary body': '0.0', 'Medium spiny neuron': '0.0', 'Mge interneuron': '0.0', 'Midbrain-derived inhibitory': '0.0', 'Miscellaneous': '0.0', 'Splatter': '0.0', 'Thalamic excitatory': '0.0', 'Upper rhombic lip': '0.0', 'Upper-layer intratelencephalic': '0.0', 'Astrocyte': '0.0', 'Bergmann glia': '0.0', 'Central nervous system macrophage': '0.0', 'Choroid plexus epithelial cell': '0.0', 'Committed oligodendrocyte precursor': '0.0', 'Ependymal cell': '0.0', 'Oligodendrocyte': '0.0', 'Oligodendrocyte precursor cell': '0.0', 'Endothelial cell': '0.0', 'Pericyte': '0.0', 'Vascular associated smooth muscle cell': '0.0', 'Fibroblast': '0.0', 'Leukocyte': '0.0', 'Basophil': '0.0', 'Eosinophil': '0.0', 'Neutrophil': '0.0', 'Classical monocyte': '0.0', 'Non-classical monocyte': '0.0', 'Intermediate monocyte': '0.7', 'T-reg': '0.0', 'GdT-cell': '0.0', 'MAIT T-cell': '0.0', 'Memory CD4 T-cell': '0.0', 'Naive CD4 T-cell': '0.1', 'Memory CD8 T-cell': '0.0', 'Naive CD8 T-cell': '0.1', 'Memory B-cell': '0.0', 'Naive B-cell': '0.1', 'Plasmacytoid DC': '0.0', 'Myeloid DC': '0.0', 'NK-cell': '0.1', 'Total PBMC': '0.2', 'Vd2 gdTCR': '0.2', 'Memory CD4 T-cell Th1\\/Th17': '0.0', 'Memory CD4 T-cell Th17': '0.1', 'Memory CD4 T-cell Th2': '0.2', 'Non-Vd2 gdTCR': '0.0', 'Memory CD4 T-cell Th1': '0.1', 'Memory CD4 T-cell TFH': '0.2', 'Terminal effector memory CD4 T-cell': '0.0', 'Central memory CD8 T-cell': '0.9', 'Effector memory CD8 T-cell': '0.0', 'Terminal effector memory CD8 T-cell': '0.3', 'Non-switched memory B-cell': '0.0', 'Plasmablast': '0.0', 'Switched memory B-cell': '0.0', 'Exhausted memory B-cell': '0.0', 'Progenitor cell': '0.0', 'Memory T-reg': '0.2', 'Naive CD4 T-cell activated': '0.0', 'Naive CD8 T-cell activated': '0.0', 'Naive T-reg': '0.1'}
2V1D, 2YBP, 2YBS, 3A6N, 3T6R, 4V2V, 4V2W, 6OIE, 6WAT, 6WAU
{}
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0.15, 0.26, 0.68, 0.03, 0.15, 0.29, 0.22, 0.02, 0.34, 0.59, 0.63, 0.19, 0.36, 0.76, 0.68, 0.95, 0.67, 0.96, 0.41, 0.85, 0.3, 0.76, 0.55, 0.94, 0.85, 0.64, 0.31, 0.81, 0.12, 0.64, 0.57, 0.38, 0.55, 0.9, 0.66, 0.08, 0.7, 0.2, 0.12, 0.36, 0.67, 0.57, 0.83, 0.81, 0.85, 0.92, 1.0, 1.0, 1.0, 1.0, 0.98, 0.87, 0.96, 0.7, 1.0, 0.86, 1.0, 1.0, 0.99, 1.0, 0.99, 0.83, 0.93, 0.72, 0.64, 0.58, 0.82, 0.52, 0.57, 0.65, 0.59, 0.74, 0.56, 0.71, 0.73, 0.78, 0.65, 0.48, 0.63, 0.54, 0.78, 0.63, 0.52, 0.3, 0.48, 0.48, 0.51, 0.09, 0.37, 0.8, 0.22, 0.01, 0.64, 0.03, 0.74, 0.69, 0.36, 0.08, 0.18, 0.37, 0.24, 0.89, 0.21, 0.1, 0.16, 0.58, 0.97, 0.33, 0.68, 0.62, 0.81, 0.3, 0.21, 0.51, 0.44, 0.01, 0.1, 0.01, 0.4, 0.03, 0.08, 0.38, 0.21, 0.03, 0.04, 0.24, 0.31, 0.14, 0.0, 0.16, 0.03, 0.37, 0.22, 0.71, 0.28, 0.16, 0.0, 0.0, 0.25, 0.33, 0.0, 0.0, 0.42, 0.38, 0.02, 0.08, 0.89, 0.69, 0.44, 0.33, 0.34, 0.58, 0.01, 0.14, 0.44, 0.49, 0.74, 0.34, 0.44, 0.01, 0.56, 0.56, 0.84, 0.1, 0.16, 0.57, 0.7, 0.08, 0.63, 0.81, 0.63, 0.25, 0.26, 0.59, 0.45, 0.03, 0.33, 0.58, 0.04, 0.4, 0.0, 0.4, 0.15, 0.57, 0.34, 0.96, 0.97, 0.1, 0.9, 0.52, 0.48, 0.12, 0.2, 0.15, 0.65, 0.64, 0.07, 0.49, 0.77, 0.1, 0.13, 0.75, 0.68, 0.3, 0.89, 0.92, 0.36, 0.79, 0.74, 0.44, 0.84, 0.36, 0.83, 0.78, 0.74, 0.95, 0.71, 0.89, 0.82, 0.87, 0.85, 0.44, 0.67, 0.34, 0.82, 0.64, 0.18, 0.72, 0.83, 0.85, 0.3, 0.27, 0.75, 0.61, 0.46, 0.37, 0.55, 0.62, 0.55, 0.63, 0.63, 0.59, 0.18, 0.36, 0.55, 0.5, 0.0, 0.51, 0.87, 0.73, 0.57, 0.89, 0.36, 0.4, 0.25, 0.73, 0.36, 0.09, 0.45, 0.3, 0.51, 0.54, 0.54, 0.09, 0.6, 0.38, 0.05, 0.32, 0.75, 0.72, 0.71, 0.3, 0.44, 0.67, 0.5, 0.0, 0.39, 0.47, 0.2, 0.28, 0.24, 0.6, 0.56, 0.59, 0.27, 0.72, 0.24, 0.45, 0.36, 0.28, 0.49, 0.28, 0.19, 0.24, 0.0, 0.0, 0.01, 0.24, 0.06, 0.0, 0.2, 0.43, 0.19, 0.21, 0.15, 0.41, 0.63, 0.42, 0.0, 0.44, 0.7, 0.25, 0.12, 0.72, 0.53, 0.26, 0.4, 0.75, 0.8, 0.46, 0.76, 0.6, 0.39, 0.3, 0.18, 0.18, 0.18, 0.22, 0.61, 0.24, 0.01, 0.58, 0.62, 0.2, 0.08, 0.61, 0.35, 0.14, 0.14, 0.07, 0.3, 0.63, 0.3, 0.77, 0.1, 0.58, 0.07, 0.48, 0.65, 0.82, 0.11, 0.76, 0.97, 0.2, 0.61, 0.86, 0.32, 0.15, 0.77, 0.21, 0.26, 0.33, 0.31, 0.43, 0.0, 0.2, 0.45, 0.95, 0.49, 0.45, 0.82, 0.45, 0.95, 0.9, 0.5, 0.72, 0.75, 0.18, 0.43, 0.07, 0.13, 0.01, 0.19, 0.05, 0.01, 0.06, 0.0, 0.02, 0.03, 0.0, 0.0, 0.02, 0.05, 0.0, 0.0, 0.13, 0.1, 0.03, 0.28, 0.49, 0.24, 0.03, 0.15, 0.5, 0.12, 0.0, 0.49, 0.72, 0.52, 0.9, 0.09, 0.47, 0.32, 0.66, 0.26, 0.49, 0.48, 0.4, 0.0, 0.26, 0.0, 0.07, 0.0, 0.02, 0.0, 0.0, 0.03, 0.19, 0.37, 0.02, 0.51, 0.84, 0.05, 0.59, 0.43, 0.19, 0.95, 0.76, 0.77, 0.84, 0.35, 0.67, 0.1, 0.38, 0.51, 0.38, 0.02, 0.02, 0.0, 0.01, 0.0, 0.01, 0.03, 0.07, 0.07, 0.39, 0.0, 0.14, 0.02, 0.48, 0.46, 1.0, 0.99, 0.74, 0.68, 0.2, 0.46, 0.09, 0.1, 0.58, 0.13, 0.9, 0.55, 0.08, 0.25, 0.15, 0.3, 0.37, 0.12, 0.02, 0.07, 0.0, 0.0, 0.0, 0.0, 0.01, 0.04, 0.03, 0.26, 0.24, 0.59, 0.31, 0.28, 0.63, 0.14, 0.0, 0.22, 0.39, 0.0, 0.01, 0.41, 0.21, 0.0, 0.15, 0.51, 0.08, 0.01, 0.56, 0.1, 0.01, 0.37, 0.58, 0.07, 0.34, 0.0, 0.18, 0.01, 0.6, 0.02, 0.52, 0.68, 0.31, 0.57, 0.02, 0.18, 0.0, 0.37, 0.07, 0.46, 0.08, 0.15, 0.03, 0.08, 0.01, 0.03, 0.26, 0.08, 0.39, 0.05, 0.15, 0.02, 0.31, 0.01, 0.02, 0.03, 0.11, 0.22, 0.7, 0.34, 0.88, 0.11, 0.48, 0.05, 0.0, 0.0, 0.12, 0.0, 0.04, 0.19, 0.1, 0.19, 0.21, 0.53, 0.48, 0.0, 0.14, 0.73, 0.34, 0.07, 0.14, 0.71, 0.2, 0.59, 0.2, 0.5, 0.04, 0.41, 0.21, 0.55, 0.28, 0.04, 0.31, 0.67, 0.13, 0.2, 0.36, 0.26, 0.26, 0.68, 0.66, 0.23, 0.6, 0.64, 0.84, 0.22, 0.42, 0.6, 0.76, 0.55, 0.06, 0.31, 0.41, 0.49, 0.02, 0.28, 0.05, 0.0, 0.41, 0.39, 0.52, 0.07, 0.19, 0.01, 0.33, 0.13, 0.24, 0.21, 0.17, 0.07, 0.07, 0.0, 0.05, 0.25, 0.02, 0.02, 0.16, 0.27, 0.01, 0.0, 0.38, 0.09, 0.01, 0.13, 0.37, 0.0, 0.0, 0.05, 0.07, 0.0, 0.14, 0.1, 0.14, 0.12, 0.39, 0.68, 0.56, 0.61, 0.96, 0.13, 0.33, 0.75, 0.53, 0.32, 0.33, 0.54, 0.58, 0.13, 0.39, 0.53, 0.42, 0.0, 0.17, 0.75, 0.14, 0.03, 0.55, 0.82, 0.48, 0.27, 0.74, 0.06, 0.75, 0.37, 0.4, 1.0, 0.87, 0.23, 0.46, 0.13, 0.55, 0.08, 0.0, 0.49, 0.59, 0.0, 0.05, 0.26, 0.48, 0.64, 0.0, 0.02, 0.38, 0.06, 0.01, 0.06, 0.57, 0.27, 0.09, 0.69, 0.27, 0.62, 0.61, 0.08, 0.06, 0.64, 0.05, 0.0, 0.43, 0.33, 0.0, 0.0, 0.25, 0.07, 0.03, 0.32, 0.44, 0.02, 0.15, 0.34, 0.0, 0.02, 0.27, 0.1, 0.48, 0.38, 0.01, 0.6, 0.81, 0.59, 0.12, 0.5, 0.76, 0.23, 0.27, 0.74, 0.52, 0.01, 0.43, 0.65, 0.09, 0.01, 0.45, 0.31, 0.03, 0.09, 0.45, 0.03, 0.0, 0.42, 0.63, 0.45, 0.0, 0.45, 0.29, 0.31, 0.07, 0.59, 0.45, 0.51, 0.04, 0.32, 0.1, 0.18, 0.02, 0.0, 0.04, 0.05, 0.02, 0.14, 0.0, 0.02, 0.31, 0.34, 0.0, 0.07, 0.87, 0.51, 0.2, 0.39, 0.04, 0.0, 0.01, 0.09, 0.08, 0.01, 0.06, 0.19, 0.03, 0.01, 0.33, 0.14, 0.01, 0.12, 0.55, 0.06, 0.03, 0.39, 0.45, 0.0, 0.08, 0.8, 0.56, 0.21, 0.16, 0.39, 0.54, 0.35, 0.08, 0.64, 0.48, 0.0, 0.0, 0.29, 0.13, 0.0, 0.0, 0.26, 0.05, 0.0, 0.02, 0.01, 0.07, 0.0, 0.01, 0.18, 0.36, 0.0, 0.15, 0.36, 0.35, 0.34, 0.54, 0.44, 0.48, 0.52, 0.52, 0.66, 0.67, 0.8, 0.56, 0.73, 0.78, 0.82, 0.85, 0.67, 0.92, 0.9, 0.86, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 0.95, 1.0, 0.95, 0.95, 0.98, 0.9, 0.98, 0.83, 0.78, 0.79]
[46.95, 59.64, 62.88, 70.92, 72.68, 69.82, 67.47, 63.77, 63.48, 59.86, 62.51, 61.91, 53.36, 61.67, 60.05, 61.65, 58.89, 60.02, 50.33, 55.71, 50.71, 59.27, 52.44, 58.59, 58.9, 55.94, 58.35, 57.62, 53.35, 61.03, 58.6, 64.01, 57.54, 60.58, 65.8, 68.72, 72.25, 79.41, 84.92, 88.28, 91.72, 93.76, 95.26, 96.33, 96.0, 97.51, 97.34, 97.21, 97.64, 97.93, 97.72, 97.61, 97.82, 98.07, 97.69, 97.2, 97.91, 96.56, 96.41, 96.11, 96.64, 97.31, 97.27, 97.73, 95.35, 96.6, 97.88, 97.93, 96.55, 97.17, 97.52, 95.93, 95.96, 96.25, 96.67, 96.36, 95.75, 96.49, 95.85, 95.44, 94.05, 92.48, 94.36, 95.26, 95.45, 97.0, 95.01, 97.09, 96.75, 95.96, 96.32, 97.56, 97.47, 97.69, 97.65, 97.85, 97.75, 97.93, 97.32, 97.13, 97.34, 97.44, 96.69, 97.08, 97.83, 97.26, 97.31, 97.94, 97.54, 97.47, 97.16, 97.69, 97.65, 97.12, 97.35, 97.75, 97.67, 96.26, 97.73, 97.26, 97.84, 97.3, 96.22, 97.27, 96.37, 95.82, 95.62, 95.8, 95.96, 95.31, 94.33, 94.17, 93.29, 86.23, 67.22, 48.99]
[0.99, 0.91, 0.97, 0.87, 0.91, 0.93, 0.87, 0.9, 0.96, 0.89, 0.95, 0.85, 0.9, 0.84, 0.96, 0.92, 0.95, 0.96, 0.99, 0.97, 1.0, 0.88, 1.0, 0.87, 0.86, 0.81, 0.82, 0.98, 0.88, 0.73, 0.65, 0.96, 0.91, 0.66, 0.9, 0.73, 0.93, 0.94, 0.83, 0.78, 0.94, 0.55, 0.85, 0.96, 0.44, 0.4, 0.34, 0.45, 0.53, 0.47, 0.47, 0.5, 0.65, 0.69, 0.47, 0.74, 0.86, 0.38, 0.95, 0.57, 0.3, 0.56, 0.38, 0.8, 0.52, 0.57, 0.54, 0.12, 0.36, 0.66, 0.5, 0.11, 0.38, 0.63, 0.49, 0.13, 0.52, 0.84, 0.83, 0.67, 0.73, 0.89, 0.4, 0.96, 0.32, 0.71, 0.72, 0.59, 0.33, 0.12, 0.33, 0.52, 0.43, 0.01, 0.55, 0.56, 0.39, 0.11, 0.62, 0.46, 0.43, 0.52, 0.2, 0.1, 0.47, 0.6, 0.31, 0.0, 0.42, 0.62, 0.14, 0.0, 0.59, 0.81, 0.48, 0.9, 0.23, 0.89, 0.67, 0.51, 0.39, 0.66, 0.62, 0.04, 0.31, 0.44, 0.43, 0.04, 0.32, 0.75, 0.71, 0.37, 0.66, 0.34, 0.49, 0.98]
RING finger
Component of the RAG complex composed of core components RAG1 and RAG2, and associated component HMGB1 or HMGB2.
RAG
null
DCAF1,RAG1 , RAG2, HMGB1 or HMGB2,
H3
mono
null
null
Homodimer
null
81.264161
0.423183
85.880074
0.617059
2,630
P15919
P15919
22199232
UbiNet, UbiBrowser
Rag1
MAASLPSTLSFSSAPDEIQHPQIKFSEWKFKLFRVRSFEKAPEEAQKEKDSSEGKPYLEQSPVVPEKPGGQNSILTQRALKLHPKFSKKFHADGKSSDKAVHQARLRHFCRICGNRFKSDGHSRRYPVHGPVDAKTQSLFRKKEKRVTSWPDLIARIFRIDVKADVDSIHPTEFCHDCWSIMHRKFSSSHSQVYFPRKVTVEWHPHTPSCDICFTAHRGLKRKRHQPNVQLSKKLKTVLNHARRDRRKRTQARVSSKEVLKKISNCSKIHLSTKLLAVDFPAHFVKSISCQICEHILADPVETSCKHLFCRICILRCLKVMGSYCPSCRYPCFPTDLESPVKSFLNILNSLMVKCPAQDCNEEVSLEKYNHHVSSHKESKETLVHINKGGRPRQHLLSLTRRAQKHRLRELKIQVKEFADKEEGGDVKAVCLTLFLLALRARNEHRQADELEAIMQGRGSGLQPAVCLAIRVNTFLSCSQYHKMYRTVKAITGRQIFQPLHALRNAEKVLLPGYHPFEWQPPLKNVSSRTDVGIIDGLSGLASSVDEYPVDTIAKRFRYDSALVSALMDMEEDILEGMRSQDLDDYLNGPFTVVVKESCDGMGDVSEKHGSGPAVPEKAVRFSFTVMRITIEHGSQNVKVFEEPKPNSELCCKPLCLMLADESDHETLTAILSPLIAEREAMKSSELTLEMGGIPRTFKFIFRGTGYDEKLVREVEGLEASGSVYICTLCDTTRLEASQNLVFHSITRSHAENLQRYEVWRSNPYHESVEELRDRVKGVSAKPFIETVPSIDALHCDIGNAAEFYKIFQLEIGEVYKHPNASKEERKRWQATLDKHLRKRMNLKPIMRMNGNFARKLMTQETVDAVCELIPSEERHEALRELMDLYLKMKPVWRSSCPAKECPESLCQYSFNSQRFAELLSTKFKYRYEGKITNYFHKTLAHVPEIIERDGSIGAWASEGNESGNKLFRRFRKMNARQSKCYEMEDVLKHHWLYTSKYLQKFMNAHNALKSSGFTMNSKETLGDPLGIEDSLESQDSMEF
Mus musculus
Nucleus
Not found
{}
1RMD, 3GNA, 3GNB, 4WWX, 5ZDZ, 5ZE0, 5ZE1, 5ZE2, 6CG0, 6CIJ, 6CIK, 6CIL, 6CIM, 6OEM, 6OEN, 6OEO, 6OEP, 6OEQ, 6OER, 6OES, 6OET, 6V0V, 6XNX, 6XNY, 6XNZ
{}
Rag1
MAASLPSTLSFSSAPDEIQHPQIKFSEWKFKLFRVRSFEKAPEEAQKEKDSSEGKPYLEQSPVVPEKPGGQNSILTQRALKLHPKFSKKFHADGKSSDKAVHQARLRHFCRICGNRFKSDGHSRRYPVHGPVDAKTQSLFRKKEKRVTSWPDLIARIFRIDVKADVDSIHPTEFCHDCWSIMHRKFSSSHSQVYFPRKVTVEWHPHTPSCDICFTAHRGLKRKRHQPNVQLSKKLKTVLNHARRDRRKRTQARVSSKEVLKKISNCSKIHLSTKLLAVDFPAHFVKSISCQICEHILADPVETSCKHLFCRICILRCLKVMGSYCPSCRYPCFPTDLESPVKSFLNILNSLMVKCPAQDCNEEVSLEKYNHHVSSHKESKETLVHINKGGRPRQHLLSLTRRAQKHRLRELKIQVKEFADKEEGGDVKAVCLTLFLLALRARNEHRQADELEAIMQGRGSGLQPAVCLAIRVNTFLSCSQYHKMYRTVKAITGRQIFQPLHALRNAEKVLLPGYHPFEWQPPLKNVSSRTDVGIIDGLSGLASSVDEYPVDTIAKRFRYDSALVSALMDMEEDILEGMRSQDLDDYLNGPFTVVVKESCDGMGDVSEKHGSGPAVPEKAVRFSFTVMRITIEHGSQNVKVFEEPKPNSELCCKPLCLMLADESDHETLTAILSPLIAEREAMKSSELTLEMGGIPRTFKFIFRGTGYDEKLVREVEGLEASGSVYICTLCDTTRLEASQNLVFHSITRSHAENLQRYEVWRSNPYHESVEELRDRVKGVSAKPFIETVPSIDALHCDIGNAAEFYKIFQLEIGEVYKHPNASKEERKRWQATLDKHLRKRMNLKPIMRMNGNFARKLMTQETVDAVCELIPSEERHEALRELMDLYLKMKPVWRSSCPAKECPESLCQYSFNSQRFAELLSTKFKYRYEGKITNYFHKTLAHVPEIIERDGSIGAWASEGNESGNKLFRRFRKMNARQSKCYEMEDVLKHHWLYTSKYLQKFMNAHNALKSSGFTMNSKETLGDPLGIEDSLESQDSMEF
Mus musculus
Nucleus
Not found
{}
1RMD, 3GNA, 3GNB, 4WWX, 5ZDZ, 5ZE0, 5ZE1, 5ZE2, 6CG0, 6CIJ, 6CIK, 6CIL, 6CIM, 6OEM, 6OEN, 6OEO, 6OEP, 6OEQ, 6OER, 6OES, 6OET, 6V0V, 6XNX, 6XNY, 6XNZ
{}
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0.98, 0.87, 0.92, 0.81, 0.78, 0.76]
null
null
null
null
null
null
null
null
null
null
null
81.387029
0.428
81.387029
0.428
472
P15919
Q60960
22199232
UbiNet, UbiBrowser
Rag1
MAASLPSTLSFSSAPDEIQHPQIKFSEWKFKLFRVRSFEKAPEEAQKEKDSSEGKPYLEQSPVVPEKPGGQNSILTQRALKLHPKFSKKFHADGKSSDKAVHQARLRHFCRICGNRFKSDGHSRRYPVHGPVDAKTQSLFRKKEKRVTSWPDLIARIFRIDVKADVDSIHPTEFCHDCWSIMHRKFSSSHSQVYFPRKVTVEWHPHTPSCDICFTAHRGLKRKRHQPNVQLSKKLKTVLNHARRDRRKRTQARVSSKEVLKKISNCSKIHLSTKLLAVDFPAHFVKSISCQICEHILADPVETSCKHLFCRICILRCLKVMGSYCPSCRYPCFPTDLESPVKSFLNILNSLMVKCPAQDCNEEVSLEKYNHHVSSHKESKETLVHINKGGRPRQHLLSLTRRAQKHRLRELKIQVKEFADKEEGGDVKAVCLTLFLLALRARNEHRQADELEAIMQGRGSGLQPAVCLAIRVNTFLSCSQYHKMYRTVKAITGRQIFQPLHALRNAEKVLLPGYHPFEWQPPLKNVSSRTDVGIIDGLSGLASSVDEYPVDTIAKRFRYDSALVSALMDMEEDILEGMRSQDLDDYLNGPFTVVVKESCDGMGDVSEKHGSGPAVPEKAVRFSFTVMRITIEHGSQNVKVFEEPKPNSELCCKPLCLMLADESDHETLTAILSPLIAEREAMKSSELTLEMGGIPRTFKFIFRGTGYDEKLVREVEGLEASGSVYICTLCDTTRLEASQNLVFHSITRSHAENLQRYEVWRSNPYHESVEELRDRVKGVSAKPFIETVPSIDALHCDIGNAAEFYKIFQLEIGEVYKHPNASKEERKRWQATLDKHLRKRMNLKPIMRMNGNFARKLMTQETVDAVCELIPSEERHEALRELMDLYLKMKPVWRSSCPAKECPESLCQYSFNSQRFAELLSTKFKYRYEGKITNYFHKTLAHVPEIIERDGSIGAWASEGNESGNKLFRRFRKMNARQSKCYEMEDVLKHHWLYTSKYLQKFMNAHNALKSSGFTMNSKETLGDPLGIEDSLESQDSMEF
Mus musculus
Nucleus
Not found
{}
1RMD, 3GNA, 3GNB, 4WWX, 5ZDZ, 5ZE0, 5ZE1, 5ZE2, 6CG0, 6CIJ, 6CIK, 6CIL, 6CIM, 6OEM, 6OEN, 6OEO, 6OEP, 6OEQ, 6OER, 6OES, 6OET, 6V0V, 6XNX, 6XNY, 6XNZ
{}
Kpna1
MSTPGKENFRLKSYKNKSLNPDEMRRRREEEGLQLRKQKREEQLFKRRNVATAEEETEEEVMSDGGFHEAQINNMEMAPGGVITSDMTDMIFSNSPEQQLSATQKFRKLLSKEPNPPIDEVINTPGVVARFVEFLKRKENCTLQFESAWVLTNIASGNSLQTRNVIQAGAVPIFIELLSSEFEDVQEQAVWALGNIAGDSTMCRDYVLNCNILPPLLQLFSKQNRLTMTRNAVWALSNLCRGKSPPPEFAKVSPCLNVLSWLLFVSDTDVLADACWALSYLSDGPNDKIQAVIDAGVCRRLVELLMHNDYKVVSPALRAVGNIVTGDDIQTQVILNCSALQSLLHLLSSPKESIKKEACWTISNITAGNRAQIQTVIDANMFPALISILQTAEFRTRKEAAWAITNATSGGSAEQIKYLVELGCIKPLCDLLTVMDAKIVQVALNGLENILRLGEQEAKRNGSGINPYCALIEEAYGLDKIEFLQSHENQEIYQKAFDLIEHYFGTEDEDSSIAPQVDLSQQQYIFQQCEAPMEGFQL
Mus musculus
Cytoplasm, Nucleus
Not found
{}
null
{}
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null
null
null
null
null
null
null
null
null
null
null
81.387029
0.428
86.428346
0.348978
1,451
P17221
P34708
22199232
UbiNet, UbiBrowser
fem-1
MTPNGHHFRTVIYNAAAVGNLQRIKVFTINSRNDRQWIIDCFNSDQDGRYPLVIAARNGHANVVEYLLEIGADPSVRGVVEFDNENIQGTPPLWAASAAGHIEIVKLLIEKANADVNQATNTRSTPLRGACYDGHLDIVKYLLEKGADPHIPNRHGHTCLMIASYRNKVGIVEELLKTGIDVNKKTERGNTALHDAAESGNVEVVKILLKHGSVLMKDIQGVDPLMGAALSGFLDVLNVLADQMPSGIHKRDALKLLGSTLLDKKMDAMSAMNCWKQSMEVPLHADDLRLVREMETFFEPQEVYEYQREAQNIAQVELLDGNIEAQRMQALVIRERILGGAHTDVHYYLRFRGAVYCDMGQMNRCYDLWKHALELQQKHFAPLYYGTITTLQSFHETFSMSLNDFVNNHHANRNLRVRSSWVKYVFNGVCLELERAAAWTGAPLLEDTECCGKERCQHATEESEYKKLVYVAVHLVNVLERLSLPSAHIDDSDEEKEPKADVRRLMIVCHELHIPLLHHTLEERIPDSNSAELGLPKAAVLEQLLELDLDVNATDKNNDTPMHILLRAREFRKSLVRALLVRGTWLFARNRHGDVVLNVMKRMKALNHANFDDLPLGRHITLAGLVANAMRVKYPKKFVGVEEQMPLELRRFYLAH
Caenorhabditis elegans
Cytoplasm
Not found
{}
null
{}
tra-1
MMAPSTEDPDTVVEAQRRGSFSKKKNANGWNKVELVDQCAKQMGSEDKQPGGGDVKTENDPSKNGLGSATSNFIQSSVPPSHQTLSNPLQLSPPAEASVAQQSGASQVFPTFQAALGASSDELLQPNATSSSTSSSASTSSIVPVVKFTNQTAPNGSTVATSVGQNVRLTINGKRVGRPPGTFKRPQNNAANSSNSGNDSDMMGDHDLTCRWKSCNSSFQTLKALVDHVQESHVQSTEQEHHAWRCEWEGCDRNETFKALYMLIVHVRRHTGEKPNKCEYPGCGKEYSRLENLKTHRRTHTGEKPYKCEFADCEKAFSNASDRAKHQNRTHSNLKPYSCQIPQCTKSYTDPSSLRKHIKAVHGDDEYEKAKKSRPANYSNRRRPDHRLAPPTGAMSHPYLATPNSGASVVAHSSVHQQNFINMALAQHHHNAQRAQQLMAATGNVMPMMDPASAAAAAQAQAHHQAQAQMLQTHMMQQAQIQAAAQMQAQVQHQAAMQAHAMQQAQMVLQNNLLGAQSLLSPFSPLLPPSRAPNVMAMLQTPPTPTSVAPMFDIMTSRAPMAPVVSAPTAPAPLVPAPVPASPVFDELREQMREVEPLQQQQQQEPMDQDLQDIRVDGDSDDEDEEEPRTPSGALLLPRGGNNGDGGFGGSGSSRASSGSGTMELSAAPISQNGSRASGSGERGMRSFLIADILQLAADFQNERLLSDVLDLAIFDTRDVRSLHNIYQVYIRAHKAIPITRRPLDWNETHQLHNLYHDPRFNRAEHQDSPAIRDRDTRFWRTIAEANTMRQRQIEPVPLDDDDEGYFDEMVHRVQNGRLNEQFMEGFESDDDDGFEDEDDVPGLGIAVYRGRRRVRREALKQANLDIQEAETAGRNVGGFGDEEDRNNRGHDQDRSFLDHYYPPMVVVVETESPQIVRDQEMMRQFEEAKKNVETDEIKKRAEAMQFGTSSSHHHTKTLLIQRALFDKTSSVRRSLLQFITISVDQEELRQSCHATSAPQGAHVVHNVVDEFDSIMRAQEDSNNRILLSLDIPAPSAVTGVSGSITHADNSALQLQQEQPTSSFSSWFPEDDPIYALPPPPPPPAPPRRRRSADNKDDSENIPKKPRHQF
Caenorhabditis elegans
Cytoplasm, Nucleus
Not found
{}
null
{}
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null
null
null
null
null
null
null
null
null
null
null
90.661052
0.299756
47.60964
0.713829
405
P19474
O14920
19675099, BioGrid E3Net
UbiNet, UbiBrowser, 31181401
TRIM21
MASAARLTMMWEEVTCPICLDPFVEPVSIECGHSFCQECISQVGKGGGSVCPVCRQRFLLKNLRPNRQLANMVNNLKEISQEAREGTQGERCAVHGERLHLFCEKDGKALCWVCAQSRKHRDHAMVPLEEAAQEYQEKLQVALGELRRKQELAEKLEVEIAIKRADWKKTVETQKSRIHAEFVQQKNFLVEEEQRQLQELEKDEREQLRILGEKEAKLAQQSQALQELISELDRRCHSSALELLQEVIIVLERSESWNLKDLDITSPELRSVCHVPGLKKMLRTCAVHITLDPDTANPWLILSEDRRQVRLGDTQQSIPGNEERFDSYPMVLGAQHFHSGKHYWEVDVTGKEAWDLGVCRDSVRRKGHFLLSSKSGFWTIWLWNKQKYEAGTYPQTPLHLQVPPCQVGIFLDYEAGMVSFYNITDHGSLIYSFSECAFTGPLRPFFSPGFNDGGKNTAPLTLCPLNIGSQGSTDY
Homo sapiens
Cytoplasm, Cytoplasmic vesicle, autophagosome, Nucleus, Cytoplasm, P-body, Cytoplasm, Stress granule
Low tissue specificity
{'Ciliated cells': '3.8', 'Basal respiratory cells': '6.8', 'Club cells': '5.8', 'Ionocytes': '3.7', 'Mucus glandular cells': '4.8', 'Serous glandular cells': '2.3', 'Gastric mucus-secreting cells': '8.8', 'Proximal enterocytes': '8.9', 'Paneth cells': '3.9', 'Distal enterocytes': '8.5', 'Intestinal goblet cells': '8.4', 'Exocrine glandular cells': '-0.716', 'Basal prostatic cells': '5.4', 'Prostatic glandular cells': '5.0', 'Breast glandular cells': '0.298', 'Breast myoepithelial cells': '0.351', 'Glandular and luminal cells': '5.9', 'Secretory cells': '8.4', 'Basal keratinocytes': '3.2', 'Suprabasal keratinocytes': '2.7', 'Basal squamous epithelial cells': '6.4', 'Squamous epithelial cells': '4.3', 'Alveolar cells type 1': '0.116', 'Alveolar cells type 2': '0.115', 'Salivary duct cells': '3.0', 'Ductal cells': '0.700', 'Hepatocytes': '0.503', 'Cholangiocytes': '11.4', 'Proximal tubular cells': '0.175', 'Distal tubular cells': '0.0', 'Collecting duct cells': '5.8', 'Mesothelial cells': '0.451', 'Sertoli cells': '0.479', 'Granulosa cells': '4.8', 'Enteroendocrine cells': '3.7', 'Pancreatic endocrine cells': '3.4', 'Leydig cells': '0.632', 'Excitatory neurons': '0.2', 'Inhibitory neurons': '0.1', 'Cone photoreceptor cells': '0.0', 'Rod photoreceptor cells': '0.0', 'Bipolar cells': '0.7', 'Horizontal cells': '0.6', 'Astrocytes': '0.0', 'Oligodendrocyte precursor cells': '0.9', 'Oligodendrocytes': '0.1', 'Microglial cells': '1.8', 'Muller glia cells': '2.4', 'Schwann cells': '0.099', 'Spermatogonia': '0.401', 'Spermatocytes': '-0.062', 'Early spermatids': '-0.578', 'Late spermatids': '-0.618', 'Oocytes': '1.5', 'Cytotrophoblasts': '6.6', 'Syncytiotrophoblasts': '9.8', 'Extravillous trophoblasts': '10.0', 'Endothelial cells': '7.8', 'Lymphatic endothelial cells': '6.9', 'Cardiomyocytes': '0.335', 'Skeletal myocytes': '-0.080', 'Smooth muscle cells': '6.3', 'Adipocytes': '8.3', 'Melanocytes': '0.101', 'Fibroblasts': '6.5', 'Peritubular cells': '0.579', 'Endometrial stromal cells': '4.5', 'Ovarian stromal cells': '6.7', 'Undifferentiated cells': '5.9', 'T-cells': '9.9', 'B-cells': '8.8', 'Plasma cells': '5.0', 'Nk-cells': '15.1', 'Granulocytes': '6.2', 'Monocytes': '7.8', 'Macrophages': '8.5', 'Hofbauer cells': '9.9', 'Kupffer cells': '10.3', 'Dendritic cells': '8.0', 'Langerhans cells': '0.466', 'Erythroid cells': '-0.084', 'Adipocytes (Subcutaneous)': '-0.368', 'Adipocytes (Visceral)': '-0.167', 'Breast glandular cells (progenitors)': '0.190', 'Adipocytes (Breast)': '-0.382', 'Colon enterocytes': '0.004', 'Colon enteroendocrine cells': '0.196', 'Enteric glia cells': '-0.129', 'Mitotic cells (Colon)': '0.005', 'Mitotic cells (Heart)': '0.486', 'Podocytes': '-0.114', 'Ascending Loop of Henle cells': '0.371', 'Intercalated cells': '-0.097', 'Cholangiocyte': '0.375', 'NK-cells (Liver)': '-0.278', 'Respiratory ciliated cells': '-0.022', 'Mitotic cells (Lung)': '0.157', 'NK-cells (Lung)': '0.110', 'B-cells (Lung)': '-0.155', 'Alpha cells': '0.333', 'Beta cells': '0.161', 'Prostate glandular cells': '-0.162', 'Prostate basal glandular cells': '0.286', 'Urothelial cells': '0.283', 'Keratinocyte (other)': '0.121', 'Keratinocyte (granular)': '-0.008', 'Hair cortex cells': '-0.113', 'Inner root sheath cells': '-0.069', 'Outer root sheath cells': '0.125', 'Sebaceous gland cells': '0.110', 'Eccrine sweat gland cells': '0.070', 'Adipocytes (Skin)': '0.019', 'Mitotic cells (Skin)': '0.236', 'Parietal cells': '-0.609', 'Chief cells': '-0.599', 'Gastric mucous cells': '-0.193', 'Gastric enteroendocrine cells': '-0.441', 'Mitotic cells (Stomach)': '0.261', 'Parafollicular cells': '-0.028', 'Thyroid glandular cells': '0.094', 'Mitotic cells (Thyroid)': '0.242', 'Adrenal cortex cells': '0.619', 'Adrenal medulla cells': '0.063', 'Mitotic cells (Adrenal gland)': '0.483', 'Minor salivary glandular cells': '0.582', 'Minor salivary gland ductal cells': '0.072', 'Minor salivary gland basal cells': '0.229', 'Mitotic cells (Minor salivary gland)': '0.376', 'Adipocytes (Minor salivary gland)': '0.211', 'Somatotropes': '-0.121', 'Lactotropes': '-0.287', 'Gonadotropes': '0.004', 'Corticotropes': '-0.352', 'Thyrotropes': '-0.054', 'Undifferentiated cells (Pituitary gland)': '0.486', 'Mitotic cells (Spleen)': '-0.016', 'Platelets': '0.115', 'Erythrocytes': '0.098', 'Hematopoietic stem cells': '0.042', 'B-cells (Spleen)': '0.028', 'NK-cells (Spleen)': '0.157', 'Amygdala excitatory': '0.1', 'Cerebellar inhibitory': '0.2', 'Cge interneuron': '0.3', 'Deep-layer corticothalamic and 6b': '0.3', 'Deep-layer intratelencephalic': '0.1', 'Deep-layer near-projecting': '0.1', 'Eccentric medium spiny neuron': '0.4', 'Hippocampal ca1-3': '0.5', 'Hippocampal ca4': '0.1', 'Hippocampal dentate gyrus': '0.3', 'Lamp5-lhx6 and chandelier': '0.3', 'Lower rhombic lip': '0.2', 'Mammillary body': '0.4', 'Medium spiny neuron': '0.6', 'Mge interneuron': '0.1', 'Midbrain-derived inhibitory': '0.6', 'Miscellaneous': '0.6', 'Splatter': '0.5', 'Thalamic excitatory': '1.3', 'Upper rhombic lip': '0.1', 'Upper-layer intratelencephalic': '0.1', 'Astrocyte': '1.5', 'Bergmann glia': '1.5', 'Central nervous system macrophage': '6.0', 'Choroid plexus epithelial cell': '2.9', 'Committed oligodendrocyte precursor': '1.0', 'Ependymal cell': '1.3', 'Oligodendrocyte': '0.1', 'Oligodendrocyte precursor cell': '2.3', 'Endothelial cell': '6.4', 'Pericyte': '5.3', 'Vascular associated smooth muscle cell': '3.1', 'Fibroblast': '5.3', 'Leukocyte': '7.4', 'Basophil': '107.0', 'Eosinophil': '312.5', 'Neutrophil': '496.9', 'Classical monocyte': '25.8', 'Non-classical monocyte': '66.1', 'Intermediate monocyte': '117.0', 'T-reg': '72.1', 'GdT-cell': '89.5', 'MAIT T-cell': '61.2', 'Memory CD4 T-cell': '76.8', 'Naive CD4 T-cell': '47.0', 'Memory CD8 T-cell': '81.1', 'Naive CD8 T-cell': '43.5', 'Memory B-cell': '50.4', 'Naive B-cell': '38.5', 'Plasmacytoid DC': '47.5', 'Myeloid DC': '92.2', 'NK-cell': '88.9', 'Total PBMC': '83.8', 'Vd2 gdTCR': '67.8', 'Memory CD4 T-cell Th1\\/Th17': '48.0', 'Memory CD4 T-cell Th17': '54.6', 'Memory CD4 T-cell Th2': '54.8', 'Non-Vd2 gdTCR': '73.7', 'Memory CD4 T-cell Th1': '58.8', 'Memory CD4 T-cell TFH': '61.9', 'Terminal effector memory CD4 T-cell': '72.8', 'Central memory CD8 T-cell': '59.9', 'Effector memory CD8 T-cell': '90.7', 'Terminal effector memory CD8 T-cell': '75.8', 'Non-switched memory B-cell': '52.6', 'Plasmablast': '62.3', 'Switched memory B-cell': '55.8', 'Exhausted memory B-cell': '52.1', 'Progenitor cell': '44.7', 'Memory T-reg': '82.4', 'Naive CD4 T-cell activated': '133.9', 'Naive CD8 T-cell activated': '163.4', 'Naive T-reg': '54.7'}
2IWG, 5JPX, 5OLM, 6FGA, 6S53, 7BBD, 8A58
{'Adipose Tissue': 21.42795099667774, 'Adrenal Gland': 16.707763565891472, 'Bladder': 21.861904761904764, 'Blood': 61.11958557588805, 'Blood Vessel': 22.62928389513109, 'Brain': 4.305000416351249, 'Breast': 20.001740740740743, 'Cervix Uteri': 26.420526315789473, 'Colon': 23.40817458279846, 'Esophagus': 21.74157577854671, 'Fallopian Tube': 25.39, 'Heart': 6.66628106852497, 'Kidney': 13.61479775280899, 'Liver': 10.388, 'Lung': 32.00464878892734, 'Muscle': 3.944284806973848, 'Nerve': 25.39305008077545, 'Ovary': 30.51811111111111, 'Pancreas': 6.808080182926829, 'Pituitary': 12.995699646643107, 'Prostate': 21.00597551020408, 'Salivary Gland': 16.434148148148147, 'Skin': 17.851811498065228, 'Small Intestine': 28.907085561497325, 'Spleen': 50.16024896265561, 'Stomach': 19.072721448467966, 'Testis': 6.377013850415512, 'Thyroid': 21.553307810107196, 'Uterus': 29.83549295774648, 'Vagina': 21.551141025641027}
IKBKB
MSWSPSLTTQTCGAWEMKERLGTGGFGNVIRWHNQETGEQIAIKQCRQELSPRNRERWCLEIQIMRRLTHPNVVAARDVPEGMQNLAPNDLPLLAMEYCQGGDLRKYLNQFENCCGLREGAILTLLSDIASALRYLHENRIIHRDLKPENIVLQQGEQRLIHKIIDLGYAKELDQGSLCTSFVGTLQYLAPELLEQQKYTVTVDYWSFGTLAFECITGFRPFLPNWQPVQWHSKVRQKSEVDIVVSEDLNGTVKFSSSLPYPNNLNSVLAERLEKWLQLMLMWHPRQRGTDPTYGPNGCFKALDDILNLKLVHILNMVTGTIHTYPVTEDESLQSLKARIQQDTGIPEEDQELLQEAGLALIPDKPATQCISDGKLNEGHTLDMDLVFLFDNSKITYETQISPRPQPESVSCILQEPKRNLAFFQLRKVWGQVWHSIQTLKEDCNRLQQGQRAAMMNLLRNNSCLSKMKNSMASMSQQLKAKLDFFKTSIQIDLEKYSEQTEFGITSDKLLLAWREMEQAVELCGRENEVKLLVERMMALQTDIVDLQRSPMGRKQGGTLDDLEEQARELYRRLREKPRDQRTEGDSQEMVRLLLQAIQSFEKKVRVIYTQLSKTVVCKQKALELLPKVEEVVSLMNEDEKTVVRLQEKRQKELWNLLKIACSKVRGPVSGSPDSMNASRLSQPGQLMSQPSTASNSLPEPAKKSEELVAEAHNLCTLLENAIQDTVREQDQSFTALDWSWLQTEEEEHSCLEQAS
Homo sapiens
Cytoplasm, Nucleus, Membrane raft
Low tissue specificity
{'Ciliated cells': '19.2', 'Basal respiratory cells': '13.3', 'Club cells': '23.6', 'Ionocytes': '15.5', 'Mucus glandular cells': '27.4', 'Serous glandular cells': '20.9', 'Gastric mucus-secreting cells': '21.2', 'Proximal enterocytes': '10.9', 'Paneth cells': '9.1', 'Distal enterocytes': '13.1', 'Intestinal goblet cells': '18.9', 'Exocrine glandular cells': '-0.695', 'Basal prostatic cells': '20.7', 'Prostatic glandular cells': '20.1', 'Breast glandular cells': '0.701', 'Breast myoepithelial cells': '0.591', 'Glandular and luminal cells': '12.6', 'Secretory cells': '13.1', 'Basal keratinocytes': '23.4', 'Suprabasal keratinocytes': '22.9', 'Basal squamous epithelial cells': '23.9', 'Squamous epithelial cells': '16.1', 'Alveolar cells type 1': '0.076', 'Alveolar cells type 2': '-0.303', 'Salivary duct cells': '22.7', 'Ductal cells': '0.635', 'Hepatocytes': '0.287', 'Cholangiocytes': '13.4', 'Proximal tubular cells': '0.116', 'Distal tubular cells': '6.1', 'Collecting duct cells': '5.8', 'Mesothelial cells': '0.421', 'Sertoli cells': '0.595', 'Granulosa cells': '7.2', 'Enteroendocrine cells': '6.8', 'Pancreatic endocrine cells': '6.8', 'Leydig cells': '0.547', 'Excitatory neurons': '19.1', 'Inhibitory neurons': '19.7', 'Cone photoreceptor cells': '49.3', 'Rod photoreceptor cells': '53.7', 'Bipolar cells': '10.2', 'Horizontal cells': '12.6', 'Astrocytes': '18.3', 'Oligodendrocyte precursor cells': '16.0', 'Oligodendrocytes': '28.1', 'Microglial cells': '55.5', 'Muller glia cells': '9.7', 'Schwann cells': '0.159', 'Spermatogonia': '0.337', 'Spermatocytes': '0.000', 'Early spermatids': '-0.596', 'Late spermatids': '-0.680', 'Oocytes': '2.2', 'Cytotrophoblasts': '10.0', 'Syncytiotrophoblasts': '13.4', 'Extravillous trophoblasts': '4.7', 'Endothelial cells': '30.9', 'Lymphatic endothelial cells': '13.9', 'Cardiomyocytes': '0.362', 'Skeletal myocytes': '0.148', 'Smooth muscle cells': '11.7', 'Adipocytes': '29.6', 'Melanocytes': '-0.059', 'Fibroblasts': '11.6', 'Peritubular cells': '0.519', 'Endometrial stromal cells': '14.0', 'Ovarian stromal cells': '10.7', 'Undifferentiated cells': '11.6', 'T-cells': '24.5', 'B-cells': '26.2', 'Plasma cells': '9.7', 'Nk-cells': '40.4', 'Granulocytes': '25.0', 'Monocytes': '20.2', 'Macrophages': '26.6', 'Hofbauer cells': '19.0', 'Kupffer cells': '25.4', 'Dendritic cells': '41.3', 'Langerhans cells': '0.234', 'Erythroid cells': '0.046', 'Adipocytes (Subcutaneous)': '-0.322', 'Adipocytes (Visceral)': '-0.456', 'Breast glandular cells (progenitors)': '0.413', 'Adipocytes (Breast)': '-0.613', 'Colon enterocytes': '-0.097', 'Colon enteroendocrine cells': '0.158', 'Enteric glia cells': '0.210', 'Mitotic cells (Colon)': '0.091', 'Mitotic cells (Heart)': '0.512', 'Podocytes': '-0.140', 'Ascending Loop of Henle cells': '0.443', 'Intercalated cells': '-0.102', 'Cholangiocyte': '0.369', 'NK-cells (Liver)': '-0.220', 'Respiratory ciliated cells': '0.059', 'Mitotic cells (Lung)': '-0.040', 'NK-cells (Lung)': '0.350', 'B-cells (Lung)': '0.163', 'Alpha cells': '0.425', 'Beta cells': '0.318', 'Prostate glandular cells': '-0.015', 'Prostate basal glandular cells': '0.529', 'Urothelial cells': '0.571', 'Keratinocyte (other)': '0.208', 'Keratinocyte (granular)': '-0.132', 'Hair cortex cells': '-0.182', 'Inner root sheath cells': '-0.170', 'Outer root sheath cells': '0.089', 'Sebaceous gland cells': '-0.039', 'Eccrine sweat gland cells': '-0.149', 'Adipocytes (Skin)': '-0.209', 'Mitotic cells (Skin)': '0.172', 'Parietal cells': '-0.629', 'Chief cells': '-0.633', 'Gastric mucous cells': '-0.249', 'Gastric enteroendocrine cells': '-0.377', 'Mitotic cells (Stomach)': '0.133', 'Parafollicular cells': '-0.021', 'Thyroid glandular cells': '-0.035', 'Mitotic cells (Thyroid)': '0.098', 'Adrenal cortex cells': '0.378', 'Adrenal medulla cells': '-0.061', 'Mitotic cells (Adrenal gland)': '0.212', 'Minor salivary glandular cells': '0.604', 'Minor salivary gland ductal cells': '0.092', 'Minor salivary gland basal cells': '0.308', 'Mitotic cells (Minor salivary gland)': '0.409', 'Adipocytes (Minor salivary gland)': '0.204', 'Somatotropes': '0.018', 'Lactotropes': '-0.068', 'Gonadotropes': '0.050', 'Corticotropes': '-0.175', 'Thyrotropes': '0.012', 'Undifferentiated cells (Pituitary gland)': '0.283', 'Mitotic cells (Spleen)': '-0.331', 'Platelets': '-0.093', 'Erythrocytes': '-0.139', 'Hematopoietic stem cells': '-0.325', 'B-cells (Spleen)': '0.457', 'NK-cells (Spleen)': '0.454', 'Amygdala excitatory': '26.8', 'Cerebellar inhibitory': '34.9', 'Cge interneuron': '34.2', 'Deep-layer corticothalamic and 6b': '25.4', 'Deep-layer intratelencephalic': '26.0', 'Deep-layer near-projecting': '22.7', 'Eccentric medium spiny neuron': '26.2', 'Hippocampal ca1-3': '32.1', 'Hippocampal ca4': '39.4', 'Hippocampal dentate gyrus': '35.2', 'Lamp5-lhx6 and chandelier': '28.8', 'Lower rhombic lip': '29.7', 'Mammillary body': '29.3', 'Medium spiny neuron': '30.2', 'Mge interneuron': '27.3', 'Midbrain-derived inhibitory': '22.0', 'Miscellaneous': '25.7', 'Splatter': '24.5', 'Thalamic excitatory': '28.9', 'Upper rhombic lip': '41.6', 'Upper-layer intratelencephalic': '24.4', 'Astrocyte': '44.3', 'Bergmann glia': '31.4', 'Central nervous system macrophage': '177.2', 'Choroid plexus epithelial cell': '51.2', 'Committed oligodendrocyte precursor': '45.9', 'Ependymal cell': '87.0', 'Oligodendrocyte': '55.9', 'Oligodendrocyte precursor cell': '32.1', 'Endothelial cell': '229.2', 'Pericyte': '29.7', 'Vascular associated smooth muscle cell': '57.0', 'Fibroblast': '43.7', 'Leukocyte': '100.4', 'Basophil': '37.7', 'Eosinophil': '5.7', 'Neutrophil': '39.8', 'Classical monocyte': '41.2', 'Non-classical monocyte': '44.0', 'Intermediate monocyte': '33.2', 'T-reg': '36.3', 'GdT-cell': '4.6', 'MAIT T-cell': '26.1', 'Memory CD4 T-cell': '5.1', 'Naive CD4 T-cell': '68.9', 'Memory CD8 T-cell': '5.5', 'Naive CD8 T-cell': '67.5', 'Memory B-cell': '4.5', 'Naive B-cell': '79.2', 'Plasmacytoid DC': '53.7', 'Myeloid DC': '46.5', 'NK-cell': '79.9', 'Total PBMC': '26.5', 'Vd2 gdTCR': '32.3', 'Memory CD4 T-cell TFH': '83.9', 'Memory CD4 T-cell Th2': '94.2', 'Memory CD4 T-cell Th17': '79.6', 'Memory CD4 T-cell Th1\\/Th17': '64.9', 'Non-Vd2 gdTCR': '27.6', 'Memory CD4 T-cell Th1': '77.4', 'Terminal effector memory CD4 T-cell': '28.7', 'Central memory CD8 T-cell': '22.0', 'Effector memory CD8 T-cell': '30.9', 'Terminal effector memory CD8 T-cell': '26.4', 'Switched memory B-cell': '25.7', 'Plasmablast': '9.7', 'Non-switched memory B-cell': '33.0', 'Exhausted memory B-cell': '26.0', 'Progenitor cell': '32.5', 'Naive CD4 T-cell activated': '63.9', 'Naive CD8 T-cell activated': '59.8', 'Memory T-reg': '94.4', 'Naive T-reg': '75.9'}
3BRT, 3BRV, 4E3C, 4KIK, 8OMV
{'Adipose Tissue': 34.76504983388705, 'Adrenal Gland': 28.13613953488372, 'Bladder': 41.54142857142857, 'Blood': 23.982386437029064, 'Blood Vessel': 30.419380524344568, 'Brain': 13.10757721423164, 'Breast': 44.40143790849673, 'Cervix Uteri': 45.844210526315784, 'Colon': 29.14707317073171, 'Esophagus': 33.743130795847755, 'Fallopian Tube': 48.4388888888889, 'Heart': 8.868621370499419, 'Kidney': 19.585955056179778, 'Liver': 10.452464601769911, 'Lung': 45.73062283737024, 'Muscle': 17.672504358655043, 'Nerve': 47.12907915993538, 'Ovary': 37.67094444444445, 'Pancreas': 12.552384146341463, 'Pituitary': 29.69009893992933, 'Prostate': 53.0158775510204, 'Salivary Gland': 32.385987654320985, 'Skin': 36.29847982310669, 'Small Intestine': 41.514171122994654, 'Spleen': 68.07, 'Stomach': 25.422869080779943, 'Testis': 24.180997229916898, 'Thyroid': 50.673062787136296, 'Uterus': 49.885, 'Vagina': 46.08365384615384}
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[0.99, 0.98, 0.97, 0.68, 0.87, 0.59, 0.88, 0.76, 0.44, 0.48, 0.55, 0.13, 0.88, 0.21, 0.12, 0.16, 0.27, 0.38, 0.51, 0.69, 0.4, 0.36, 0.58, 0.45, 0.7, 0.08, 0.04, 0.29, 0.22, 0.09, 0.15, 0.06, 0.26, 0.09, 0.59, 0.85, 0.68, 0.49, 0.46, 0.3, 0.04, 0.06, 0.02, 0.08, 0.29, 0.07, 0.55, 0.72, 0.97, 0.28, 0.53, 0.7, 0.65, 0.25, 0.46, 0.69, 0.27, 0.01, 0.42, 0.33, 0.02, 0.04, 0.57, 0.0, 0.02, 0.68, 0.51, 0.08, 0.79, 0.2, 0.7, 0.07, 0.03, 0.03, 0.35, 0.3, 0.5, 0.9, 0.32, 0.15, 0.91, 0.4, 0.01, 0.41, 0.83, 0.41, 0.2, 0.36, 0.24, 0.78, 0.06, 0.36, 0.06, 0.03, 0.01, 0.1, 0.17, 0.19, 0.09, 0.52, 0.1, 0.29, 0.34, 0.0, 0.18, 0.59, 0.21, 0.11, 0.44, 0.37, 0.25, 0.55, 0.12, 0.21, 0.04, 0.01, 0.06, 0.61, 0.05, 0.0, 0.16, 0.01, 0.11, 0.02, 0.01, 0.0, 0.45, 0.03, 0.0, 0.02, 0.27, 0.0, 0.0, 0.26, 0.18, 0.0, 0.15, 0.69, 0.36, 0.57, 0.01, 0.0, 0.0, 0.08, 0.04, 0.01, 0.17, 0.0, 0.41, 0.05, 0.0, 0.13, 0.04, 0.21, 0.61, 0.33, 1.0, 0.63, 0.28, 0.14, 0.27, 0.05, 0.09, 0.02, 0.24, 0.24, 0.02, 0.08, 0.27, 0.08, 0.34, 0.33, 0.17, 0.71, 0.93, 0.73, 0.47, 0.52, 0.02, 0.65, 0.24, 0.55, 0.11, 0.41, 0.26, 0.51, 0.57, 0.01, 0.03, 0.0, 0.01, 0.03, 0.05, 0.27, 0.34, 0.76, 0.49, 0.63, 0.01, 0.37, 0.17, 0.07, 0.01, 0.0, 0.02, 0.01, 0.04, 0.0, 0.0, 0.02, 0.0, 0.01, 0.0, 0.05, 0.0, 0.02, 0.03, 0.36, 0.27, 0.16, 0.01, 0.06, 0.02, 0.42, 0.83, 0.33, 0.71, 0.44, 0.82, 0.52, 0.12, 0.23, 0.57, 0.3, 0.0, 0.62, 0.57, 0.12, 0.49, 0.6, 0.49, 0.12, 0.0, 0.04, 0.01, 0.29, 0.46, 0.26, 0.18, 0.66, 0.45, 0.5, 0.26, 0.36, 0.33, 0.33, 0.34, 0.52, 0.13, 0.2, 0.44, 0.07, 0.12, 0.3, 0.13, 0.04, 0.59, 0.13, 0.02, 0.16, 0.53, 0.47, 0.01, 0.21, 0.51, 0.04, 0.0, 0.18, 0.17, 0.0, 0.0, 0.15, 0.18, 0.5, 0.29, 0.85, 0.44, 0.01, 0.0, 0.36, 0.14, 0.92, 0.95, 0.43, 0.26, 0.79, 0.49, 0.04, 0.01, 0.07, 0.56, 0.12, 0.0, 0.29, 0.47, 0.08, 0.28, 0.74, 0.29, 0.35, 0.13, 0.0, 0.03, 0.0, 0.01, 0.02, 0.0, 0.25, 0.44, 0.35, 0.44, 0.23, 0.18, 0.13, 0.04, 0.27, 0.09, 0.64, 0.56, 0.91, 0.12, 0.44, 0.04, 0.5, 0.4, 0.0, 0.19, 0.3, 0.29, 0.0, 0.4, 0.8, 0.6, 0.24, 0.66, 0.04, 0.41, 0.35, 0.87, 0.25, 0.04, 0.18, 0.04, 0.0, 0.32, 0.59, 0.51, 0.0, 0.45, 0.58, 0.11, 0.46, 0.56, 0.93, 0.55, 0.4, 0.0, 0.13, 0.21, 0.06, 0.28, 0.56, 0.93, 0.68, 0.71, 0.39, 0.36, 0.34, 0.43, 0.19, 0.33, 0.18, 0.4, 0.63, 0.06, 0.07, 0.01, 0.02, 0.0, 0.02, 0.11, 0.41, 0.61, 0.33, 0.57, 0.69, 0.05, 0.69, 0.29, 0.79, 0.12, 0.94, 0.43, 0.43, 0.81, 0.28, 0.06, 0.65, 0.2, 0.0, 0.35, 0.28, 0.0, 0.29, 0.83, 0.54, 0.22, 0.71, 0.25, 0.63, 0.0, 0.28, 0.15, 0.74, 0.22, 0.04, 0.44, 0.45, 0.02, 0.12, 0.01, 0.07, 0.01, 0.03, 0.07, 0.07, 0.0, 0.26, 0.12, 0.04, 0.24, 0.39, 0.12, 0.04, 0.39, 0.07, 0.03, 0.2, 0.28, 0.0, 0.07, 0.52, 0.0, 0.03, 0.09, 0.45, 0.08, 0.0, 0.27, 0.45, 0.28, 0.17, 0.44, 0.46, 0.03, 0.22, 0.68, 0.2, 0.16, 0.67, 0.53, 0.0, 0.31, 0.41, 0.27, 0.15, 0.7, 0.51, 0.05, 0.47, 0.53, 0.37, 0.09, 0.5, 0.63, 0.02, 0.37, 0.58, 0.2, 0.01, 0.42, 0.51, 0.18, 0.1, 0.5, 0.54, 0.08, 0.6, 0.52, 0.24, 0.46, 0.98, 0.79, 0.6, 0.2, 0.62, 0.31, 0.68, 0.83, 0.12, 0.29, 0.61, 0.21, 0.01, 0.5, 0.62, 0.04, 0.35, 0.66, 0.36, 0.01, 0.63, 0.76, 0.16, 0.37, 0.22, 0.46, 0.78, 0.4, 0.07, 0.58, 0.58, 0.06, 0.3, 0.52, 0.35, 0.03, 0.5, 0.49, 0.03, 0.21, 0.55, 0.35, 0.0, 0.42, 0.58, 0.09, 0.51, 0.77, 0.35, 0.77, 0.28, 0.75, 0.87, 0.94, 0.84, 0.65, 0.04, 0.52, 0.01, 0.28, 0.5, 0.07, 0.08, 0.46, 0.44, 0.0, 0.42, 0.3, 0.05, 0.03, 0.42, 0.52, 0.03, 0.16, 0.58, 0.4, 0.48, 0.82, 0.85, 0.56, 0.42, 0.64, 0.73, 0.2, 0.37, 0.02, 0.41, 0.45, 0.0, 0.05, 0.48, 0.01, 0.0, 0.54, 0.38, 0.0, 0.22, 0.69, 0.09, 0.02, 0.49, 0.73, 0.26, 0.02, 0.44, 0.43, 0.01, 0.0, 0.42, 0.13, 0.0, 0.15, 0.56, 0.01, 0.13, 0.36, 0.06, 0.08, 0.27, 0.36, 0.07, 0.5, 0.52, 0.02, 0.28, 0.53, 0.42, 0.01, 0.54, 0.6, 0.09, 0.24, 0.56, 0.35, 0.02, 0.4, 0.5, 0.07, 0.29, 0.43, 0.28, 0.04, 0.51, 0.59, 0.15, 0.15, 0.49, 0.47, 0.01, 0.54, 0.54, 0.21, 0.47, 0.67, 0.46, 0.14, 0.5, 0.66, 0.43, 0.31, 0.55, 0.55, 0.76, 0.84, 0.86, 0.83, 1.0, 0.96, 0.98, 0.99, 1.0, 1.0, 1.0, 0.98, 1.0, 0.98, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 0.98, 1.0, 0.98, 1.0, 1.0, 1.0, 1.0, 1.0, 0.99, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 0.84, 0.75, 0.67, 0.71, 0.67, 0.66, 0.48, 0.72, 0.67, 0.62, 0.51, 0.53, 0.6, 0.44, 0.63, 0.63, 0.61, 0.54, 0.47, 0.63, 0.62, 0.63, 0.48, 0.44, 0.55, 0.55, 0.5, 0.46, 0.51, 0.65, 0.74, 0.46, 0.59, 0.81, 0.56, 0.41, 0.78, 0.89, 0.59, 0.7, 0.37, 0.59, 0.73, 0.77, 0.78, 0.83, 0.96, 0.96, 0.75, 0.84, 0.94, 0.8, 0.84, 0.86, 0.95, 0.96, 0.95, 1.0]
RING finger
Component of a SCF(SKP2)-like complex containing CUL1, SKP1, TRIM21 and SKP2.
SCF
null
IRF8, CALR, CUL1, FBXW11, HSPA5, IKBKB, IRF3, SKP1 , VCP,SKP2, DCP2 ,ULK1, BECN1,GABARAP, GABARAPL1, GABARAPL2 , MAP1LC3C,SQSTM1,IRF3 , NMI, IFI35 , CUL1, TRIM21
USP4, IKBKB, TRIM21, CDKN1B, IRF3, IRF8, MNI
mono, 63
null
UBE2D2, UBE2D1, UBE2E1, UBE2E2
Homotrimer
null
90.718042
0.406716
85.899193
0.372328
888
P19474
O95863
30502437
UbiBrowser
TRIM21
MASAARLTMMWEEVTCPICLDPFVEPVSIECGHSFCQECISQVGKGGGSVCPVCRQRFLLKNLRPNRQLANMVNNLKEISQEAREGTQGERCAVHGERLHLFCEKDGKALCWVCAQSRKHRDHAMVPLEEAAQEYQEKLQVALGELRRKQELAEKLEVEIAIKRADWKKTVETQKSRIHAEFVQQKNFLVEEEQRQLQELEKDEREQLRILGEKEAKLAQQSQALQELISELDRRCHSSALELLQEVIIVLERSESWNLKDLDITSPELRSVCHVPGLKKMLRTCAVHITLDPDTANPWLILSEDRRQVRLGDTQQSIPGNEERFDSYPMVLGAQHFHSGKHYWEVDVTGKEAWDLGVCRDSVRRKGHFLLSSKSGFWTIWLWNKQKYEAGTYPQTPLHLQVPPCQVGIFLDYEAGMVSFYNITDHGSLIYSFSECAFTGPLRPFFSPGFNDGGKNTAPLTLCPLNIGSQGSTDY
Homo sapiens
Cytoplasm, Cytoplasmic vesicle, autophagosome, Nucleus, Cytoplasm, P-body, Cytoplasm, Stress granule
Low tissue specificity
{'Ciliated cells': '3.8', 'Basal respiratory cells': '6.8', 'Club cells': '5.8', 'Ionocytes': '3.7', 'Mucus glandular cells': '4.8', 'Serous glandular cells': '2.3', 'Gastric mucus-secreting cells': '8.8', 'Proximal enterocytes': '8.9', 'Paneth cells': '3.9', 'Distal enterocytes': '8.5', 'Intestinal goblet cells': '8.4', 'Exocrine glandular cells': '-0.716', 'Basal prostatic cells': '5.4', 'Prostatic glandular cells': '5.0', 'Breast glandular cells': '0.298', 'Breast myoepithelial cells': '0.351', 'Glandular and luminal cells': '5.9', 'Secretory cells': '8.4', 'Basal keratinocytes': '3.2', 'Suprabasal keratinocytes': '2.7', 'Basal squamous epithelial cells': '6.4', 'Squamous epithelial cells': '4.3', 'Alveolar cells type 1': '0.116', 'Alveolar cells type 2': '0.115', 'Salivary duct cells': '3.0', 'Ductal cells': '0.700', 'Hepatocytes': '0.503', 'Cholangiocytes': '11.4', 'Proximal tubular cells': '0.175', 'Distal tubular cells': '0.0', 'Collecting duct cells': '5.8', 'Mesothelial cells': '0.451', 'Sertoli cells': '0.479', 'Granulosa cells': '4.8', 'Enteroendocrine cells': '3.7', 'Pancreatic endocrine cells': '3.4', 'Leydig cells': '0.632', 'Excitatory neurons': '0.2', 'Inhibitory neurons': '0.1', 'Cone photoreceptor cells': '0.0', 'Rod photoreceptor cells': '0.0', 'Bipolar cells': '0.7', 'Horizontal cells': '0.6', 'Astrocytes': '0.0', 'Oligodendrocyte precursor cells': '0.9', 'Oligodendrocytes': '0.1', 'Microglial cells': '1.8', 'Muller glia cells': '2.4', 'Schwann cells': '0.099', 'Spermatogonia': '0.401', 'Spermatocytes': '-0.062', 'Early spermatids': '-0.578', 'Late spermatids': '-0.618', 'Oocytes': '1.5', 'Cytotrophoblasts': '6.6', 'Syncytiotrophoblasts': '9.8', 'Extravillous trophoblasts': '10.0', 'Endothelial cells': '7.8', 'Lymphatic endothelial cells': '6.9', 'Cardiomyocytes': '0.335', 'Skeletal myocytes': '-0.080', 'Smooth muscle cells': '6.3', 'Adipocytes': '8.3', 'Melanocytes': '0.101', 'Fibroblasts': '6.5', 'Peritubular cells': '0.579', 'Endometrial stromal cells': '4.5', 'Ovarian stromal cells': '6.7', 'Undifferentiated cells': '5.9', 'T-cells': '9.9', 'B-cells': '8.8', 'Plasma cells': '5.0', 'Nk-cells': '15.1', 'Granulocytes': '6.2', 'Monocytes': '7.8', 'Macrophages': '8.5', 'Hofbauer cells': '9.9', 'Kupffer cells': '10.3', 'Dendritic cells': '8.0', 'Langerhans cells': '0.466', 'Erythroid cells': '-0.084', 'Adipocytes (Subcutaneous)': '-0.368', 'Adipocytes (Visceral)': '-0.167', 'Breast glandular cells (progenitors)': '0.190', 'Adipocytes (Breast)': '-0.382', 'Colon enterocytes': '0.004', 'Colon enteroendocrine cells': '0.196', 'Enteric glia cells': '-0.129', 'Mitotic cells (Colon)': '0.005', 'Mitotic cells (Heart)': '0.486', 'Podocytes': '-0.114', 'Ascending Loop of Henle cells': '0.371', 'Intercalated cells': '-0.097', 'Cholangiocyte': '0.375', 'NK-cells (Liver)': '-0.278', 'Respiratory ciliated cells': '-0.022', 'Mitotic cells (Lung)': '0.157', 'NK-cells (Lung)': '0.110', 'B-cells (Lung)': '-0.155', 'Alpha cells': '0.333', 'Beta cells': '0.161', 'Prostate glandular cells': '-0.162', 'Prostate basal glandular cells': '0.286', 'Urothelial cells': '0.283', 'Keratinocyte (other)': '0.121', 'Keratinocyte (granular)': '-0.008', 'Hair cortex cells': '-0.113', 'Inner root sheath cells': '-0.069', 'Outer root sheath cells': '0.125', 'Sebaceous gland cells': '0.110', 'Eccrine sweat gland cells': '0.070', 'Adipocytes (Skin)': '0.019', 'Mitotic cells (Skin)': '0.236', 'Parietal cells': '-0.609', 'Chief cells': '-0.599', 'Gastric mucous cells': '-0.193', 'Gastric enteroendocrine cells': '-0.441', 'Mitotic cells (Stomach)': '0.261', 'Parafollicular cells': '-0.028', 'Thyroid glandular cells': '0.094', 'Mitotic cells (Thyroid)': '0.242', 'Adrenal cortex cells': '0.619', 'Adrenal medulla cells': '0.063', 'Mitotic cells (Adrenal gland)': '0.483', 'Minor salivary glandular cells': '0.582', 'Minor salivary gland ductal cells': '0.072', 'Minor salivary gland basal cells': '0.229', 'Mitotic cells (Minor salivary gland)': '0.376', 'Adipocytes (Minor salivary gland)': '0.211', 'Somatotropes': '-0.121', 'Lactotropes': '-0.287', 'Gonadotropes': '0.004', 'Corticotropes': '-0.352', 'Thyrotropes': '-0.054', 'Undifferentiated cells (Pituitary gland)': '0.486', 'Mitotic cells (Spleen)': '-0.016', 'Platelets': '0.115', 'Erythrocytes': '0.098', 'Hematopoietic stem cells': '0.042', 'B-cells (Spleen)': '0.028', 'NK-cells (Spleen)': '0.157', 'Amygdala excitatory': '0.1', 'Cerebellar inhibitory': '0.2', 'Cge interneuron': '0.3', 'Deep-layer corticothalamic and 6b': '0.3', 'Deep-layer intratelencephalic': '0.1', 'Deep-layer near-projecting': '0.1', 'Eccentric medium spiny neuron': '0.4', 'Hippocampal ca1-3': '0.5', 'Hippocampal ca4': '0.1', 'Hippocampal dentate gyrus': '0.3', 'Lamp5-lhx6 and chandelier': '0.3', 'Lower rhombic lip': '0.2', 'Mammillary body': '0.4', 'Medium spiny neuron': '0.6', 'Mge interneuron': '0.1', 'Midbrain-derived inhibitory': '0.6', 'Miscellaneous': '0.6', 'Splatter': '0.5', 'Thalamic excitatory': '1.3', 'Upper rhombic lip': '0.1', 'Upper-layer intratelencephalic': '0.1', 'Astrocyte': '1.5', 'Bergmann glia': '1.5', 'Central nervous system macrophage': '6.0', 'Choroid plexus epithelial cell': '2.9', 'Committed oligodendrocyte precursor': '1.0', 'Ependymal cell': '1.3', 'Oligodendrocyte': '0.1', 'Oligodendrocyte precursor cell': '2.3', 'Endothelial cell': '6.4', 'Pericyte': '5.3', 'Vascular associated smooth muscle cell': '3.1', 'Fibroblast': '5.3', 'Leukocyte': '7.4', 'Basophil': '107.0', 'Eosinophil': '312.5', 'Neutrophil': '496.9', 'Classical monocyte': '25.8', 'Non-classical monocyte': '66.1', 'Intermediate monocyte': '117.0', 'T-reg': '72.1', 'GdT-cell': '89.5', 'MAIT T-cell': '61.2', 'Memory CD4 T-cell': '76.8', 'Naive CD4 T-cell': '47.0', 'Memory CD8 T-cell': '81.1', 'Naive CD8 T-cell': '43.5', 'Memory B-cell': '50.4', 'Naive B-cell': '38.5', 'Plasmacytoid DC': '47.5', 'Myeloid DC': '92.2', 'NK-cell': '88.9', 'Total PBMC': '83.8', 'Vd2 gdTCR': '67.8', 'Memory CD4 T-cell Th1\\/Th17': '48.0', 'Memory CD4 T-cell Th17': '54.6', 'Memory CD4 T-cell Th2': '54.8', 'Non-Vd2 gdTCR': '73.7', 'Memory CD4 T-cell Th1': '58.8', 'Memory CD4 T-cell TFH': '61.9', 'Terminal effector memory CD4 T-cell': '72.8', 'Central memory CD8 T-cell': '59.9', 'Effector memory CD8 T-cell': '90.7', 'Terminal effector memory CD8 T-cell': '75.8', 'Non-switched memory B-cell': '52.6', 'Plasmablast': '62.3', 'Switched memory B-cell': '55.8', 'Exhausted memory B-cell': '52.1', 'Progenitor cell': '44.7', 'Memory T-reg': '82.4', 'Naive CD4 T-cell activated': '133.9', 'Naive CD8 T-cell activated': '163.4', 'Naive T-reg': '54.7'}
2IWG, 5JPX, 5OLM, 6FGA, 6S53, 7BBD, 8A58
{'Adipose Tissue': 21.42795099667774, 'Adrenal Gland': 16.707763565891472, 'Bladder': 21.861904761904764, 'Blood': 61.11958557588805, 'Blood Vessel': 22.62928389513109, 'Brain': 4.305000416351249, 'Breast': 20.001740740740743, 'Cervix Uteri': 26.420526315789473, 'Colon': 23.40817458279846, 'Esophagus': 21.74157577854671, 'Fallopian Tube': 25.39, 'Heart': 6.66628106852497, 'Kidney': 13.61479775280899, 'Liver': 10.388, 'Lung': 32.00464878892734, 'Muscle': 3.944284806973848, 'Nerve': 25.39305008077545, 'Ovary': 30.51811111111111, 'Pancreas': 6.808080182926829, 'Pituitary': 12.995699646643107, 'Prostate': 21.00597551020408, 'Salivary Gland': 16.434148148148147, 'Skin': 17.851811498065228, 'Small Intestine': 28.907085561497325, 'Spleen': 50.16024896265561, 'Stomach': 19.072721448467966, 'Testis': 6.377013850415512, 'Thyroid': 21.553307810107196, 'Uterus': 29.83549295774648, 'Vagina': 21.551141025641027}
SNAI1
MPRSFLVRKPSDPNRKPNYSELQDSNPEFTFQQPYDQAHLLAAIPPPEILNPTASLPMLIWDSVLAPQAQPIAWASLRLQESPRVAELTSLSDEDSGKGSQPPSPPSPAPSSFSSTSVSSLEAEAYAAFPGLGQVPKQLAQLSEAKDLQARKAFNCKYCNKEYLSLGALKMHIRSHTLPCVCGTCGKAFSRPWLLQGHVRTHTGEKPFSCPHCSRAFADRSNLRAHLQTHSDVKKYQCQACARTFSRMSLLHKHQESGCSGCPR
Homo sapiens
Nucleus, Cytoplasm
Tissue enhanced (adipose)
{'Ciliated cells': '3.0', 'Basal respiratory cells': '0.5', 'Club cells': '1.4', 'Ionocytes': '0.0', 'Mucus glandular cells': '3.4', 'Serous glandular cells': '1.3', 'Gastric mucus-secreting cells': '13.0', 'Proximal enterocytes': '1.8', 'Paneth cells': '1.7', 'Distal enterocytes': '3.0', 'Intestinal goblet cells': '4.6', 'Exocrine glandular cells': '-0.438', 'Basal prostatic cells': '0.8', 'Prostatic glandular cells': '0.5', 'Breast glandular cells': '-0.454', 'Breast myoepithelial cells': '-0.449', 'Glandular and luminal cells': '8.1', 'Secretory cells': '1.2', 'Basal keratinocytes': '1.4', 'Suprabasal keratinocytes': '1.3', 'Basal squamous epithelial cells': '2.4', 'Squamous epithelial cells': '7.0', 'Alveolar cells type 1': '0.107', 'Alveolar cells type 2': '-0.021', 'Salivary duct cells': '1.7', 'Ductal cells': '0.546', 'Hepatocytes': '0.050', 'Cholangiocytes': '3.8', 'Proximal tubular cells': '-0.020', 'Distal tubular cells': '0.0', 'Collecting duct cells': '0.0', 'Mesothelial cells': '-0.194', 'Sertoli cells': '0.277', 'Granulosa cells': '3.1', 'Enteroendocrine cells': '1.4', 'Pancreatic endocrine cells': '6.8', 'Leydig cells': '0.349', 'Excitatory neurons': '0.5', 'Inhibitory neurons': '0.4', 'Cone photoreceptor cells': '0.0', 'Rod photoreceptor cells': '0.4', 'Bipolar cells': '0.2', 'Horizontal cells': '1.3', 'Astrocytes': '0.3', 'Oligodendrocyte precursor cells': '0.0', 'Oligodendrocytes': '0.7', 'Microglial cells': '0.0', 'Muller glia cells': '1.5', 'Schwann cells': '0.083', 'Spermatogonia': '0.405', 'Spermatocytes': '0.168', 'Early spermatids': '-0.392', 'Late spermatids': '-0.387', 'Oocytes': '6.6', 'Cytotrophoblasts': '10.3', 'Syncytiotrophoblasts': '13.7', 'Extravillous trophoblasts': '91.2', 'Endothelial cells': '51.2', 'Lymphatic endothelial cells': '5.2', 'Cardiomyocytes': '-0.215', 'Skeletal myocytes': '-0.042', 'Smooth muscle cells': '13.9', 'Adipocytes': '160.3', 'Melanocytes': '-0.179', 'Fibroblasts': '24.6', 'Peritubular cells': '0.312', 'Endometrial stromal cells': '17.5', 'Ovarian stromal cells': '3.2', 'Undifferentiated cells': '4.8', 'T-cells': '9.3', 'B-cells': '7.6', 'Plasma cells': '2.4', 'Nk-cells': '2.8', 'Granulocytes': '0.4', 'Monocytes': '7.4', 'Macrophages': '28.7', 'Hofbauer cells': '15.4', 'Kupffer cells': '5.1', 'Dendritic cells': '5.3', 'Langerhans cells': '-0.145', 'Erythroid cells': '0.131', 'Adipocytes (Subcutaneous)': '0.058', 'Adipocytes (Visceral)': '0.161', 'Breast glandular cells (progenitors)': '-0.288', 'Adipocytes (Breast)': '0.628', 'Colon enterocytes': '-0.066', 'Colon enteroendocrine cells': '0.219', 'Enteric glia cells': '0.019', 'Mitotic cells (Colon)': '0.057', 'Mitotic cells (Heart)': '0.130', 'Podocytes': '0.135', 'Ascending Loop of Henle cells': '0.161', 'Intercalated cells': '0.039', 'Cholangiocyte': '0.486', 'NK-cells (Liver)': '-0.114', 'Respiratory ciliated cells': '-0.047', 'Mitotic cells (Lung)': '-0.124', 'NK-cells (Lung)': '0.163', 'B-cells (Lung)': '0.040', 'Alpha cells': '0.311', 'Beta cells': '0.197', 'Prostate glandular cells': '-0.199', 'Prostate basal glandular cells': '0.094', 'Urothelial cells': '0.216', 'Keratinocyte (other)': '-0.391', 'Keratinocyte (granular)': '-0.074', 'Hair cortex cells': '0.177', 'Inner root sheath cells': '0.166', 'Outer root sheath cells': '0.075', 'Sebaceous gland cells': '-0.016', 'Eccrine sweat gland cells': '0.300', 'Adipocytes (Skin)': '0.328', 'Mitotic cells (Skin)': '-0.180', 'Parietal cells': '-0.642', 'Chief cells': '-0.565', 'Gastric mucous cells': '-0.481', 'Gastric enteroendocrine cells': '-0.450', 'Mitotic cells (Stomach)': '-0.142', 'Parafollicular cells': '-0.012', 'Thyroid glandular cells': '0.192', 'Mitotic cells (Thyroid)': '-0.094', 'Adrenal cortex cells': '0.162', 'Adrenal medulla cells': '0.031', 'Mitotic cells (Adrenal gland)': '-0.001', 'Minor salivary glandular cells': '0.387', 'Minor salivary gland ductal cells': '0.039', 'Minor salivary gland basal cells': '0.081', 'Mitotic cells (Minor salivary gland)': '0.182', 'Adipocytes (Minor salivary gland)': '0.191', 'Somatotropes': '-0.152', 'Lactotropes': '-0.312', 'Gonadotropes': '-0.068', 'Corticotropes': '-0.105', 'Thyrotropes': '-0.112', 'Undifferentiated cells (Pituitary gland)': '0.126', 'Mitotic cells (Spleen)': '-0.360', 'Platelets': '-0.087', 'Erythrocytes': '-0.019', 'Hematopoietic stem cells': '-0.235', 'B-cells (Spleen)': '0.032', 'NK-cells (Spleen)': '0.100', 'Amygdala excitatory': '0.9', 'Cerebellar inhibitory': '1.0', 'Cge interneuron': '0.5', 'Deep-layer corticothalamic and 6b': '0.5', 'Deep-layer intratelencephalic': '0.6', 'Deep-layer near-projecting': '0.7', 'Eccentric medium spiny neuron': '0.8', 'Hippocampal ca1-3': '0.7', 'Hippocampal ca4': '0.2', 'Hippocampal dentate gyrus': '0.2', 'Lamp5-lhx6 and chandelier': '0.5', 'Lower rhombic lip': '0.5', 'Mammillary body': '0.6', 'Medium spiny neuron': '1.3', 'Mge interneuron': '0.5', 'Midbrain-derived inhibitory': '0.4', 'Miscellaneous': '0.8', 'Splatter': '0.7', 'Thalamic excitatory': '0.6', 'Upper rhombic lip': '0.9', 'Upper-layer intratelencephalic': '1.0', 'Astrocyte': '0.8', 'Bergmann glia': '0.1', 'Central nervous system macrophage': '0.2', 'Choroid plexus epithelial cell': '0.0', 'Committed oligodendrocyte precursor': '0.5', 'Ependymal cell': '0.1', 'Oligodendrocyte': '0.7', 'Oligodendrocyte precursor cell': '1.1', 'Endothelial cell': '1.4', 'Pericyte': '0.9', 'Vascular associated smooth muscle cell': '0.6', 'Fibroblast': '3.6', 'Leukocyte': '0.4', 'Basophil': '5.0', 'Eosinophil': '0.0', 'Neutrophil': '0.8', 'Classical monocyte': '85.9', 'Non-classical monocyte': '0.7', 'Intermediate monocyte': '2.3', 'T-reg': '0.8', 'GdT-cell': '0.0', 'MAIT T-cell': '0.9', 'Memory CD4 T-cell': '0.0', 'Naive CD4 T-cell': '12.8', 'Memory CD8 T-cell': '0.0', 'Naive CD8 T-cell': '21.0', 'Memory B-cell': '0.0', 'Naive B-cell': '3.4', 'Plasmacytoid DC': '7.4', 'Myeloid DC': '31.8', 'NK-cell': '4.1', 'Total PBMC': '10.9', 'Vd2 gdTCR': '2.5', 'Memory CD4 T-cell Th1\\/Th17': '7.5', 'Memory CD4 T-cell Th17': '8.6', 'Memory CD4 T-cell Th2': '12.3', 'Non-Vd2 gdTCR': '3.3', 'Memory CD4 T-cell Th1': '14.8', 'Memory CD4 T-cell TFH': '5.9', 'Terminal effector memory CD4 T-cell': '1.2', 'Central memory CD8 T-cell': '1.4', 'Effector memory CD8 T-cell': '1.3', 'Terminal effector memory CD8 T-cell': '1.3', 'Non-switched memory B-cell': '1.3', 'Plasmablast': '0.0', 'Switched memory B-cell': '1.1', 'Exhausted memory B-cell': '3.2', 'Progenitor cell': '1.9', 'Memory T-reg': '5.9', 'Naive CD4 T-cell activated': '7.4', 'Naive CD8 T-cell activated': '6.4', 'Naive T-reg': '3.7'}
2Y48, 3W5K, 3ZMT, 4QLI, 8BOX, 8F59, 8FDV
{'Adipose Tissue': 32.84898754152824, 'Adrenal Gland': 16.556244186046513, 'Bladder': 11.017809523809523, 'Blood': 6.108834230355221, 'Blood Vessel': 24.922914606741575, 'Brain': 3.1862913323239965, 'Breast': 28.395642701525055, 'Cervix Uteri': 11.557684210526316, 'Colon': 8.116739794608472, 'Esophagus': 7.567145051903115, 'Fallopian Tube': 21.604, 'Heart': 9.809673519163765, 'Kidney': 9.212224719101124, 'Liver': 4.088857522123893, 'Lung': 34.62546885813149, 'Muscle': 1.9400566625155664, 'Nerve': 17.88494184168013, 'Ovary': 5.357778333333333, 'Pancreas': 2.335628048780488, 'Pituitary': 12.85375265017668, 'Prostate': 8.240596734693877, 'Salivary Gland': 6.574512345679012, 'Skin': 9.561411221669433, 'Small Intestine': 5.927605347593582, 'Spleen': 17.578145228215767, 'Stomach': 9.012349860724234, 'Testis': 9.602681440443211, 'Thyroid': 34.892254211332315, 'Uterus': 12.107514084507043, 'Vagina': 9.61338782051282}
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[48.41, 39.53, 40.05, 37.88, 42.05, 41.57, 45.01, 38.4, 42.73, 44.22, 42.5, 45.93, 50.63, 36.08, 39.98, 40.63, 37.75, 29.39, 34.01, 40.12, 37.71, 37.85, 36.61, 31.29, 35.97, 33.68, 33.07, 29.44, 31.98, 30.93, 27.89, 30.1, 32.5, 39.79, 31.65, 36.89, 36.41, 37.22, 40.31, 39.89, 38.7, 34.21, 38.35, 45.15, 56.57, 57.32, 58.33, 48.36, 46.38, 43.6, 47.68, 39.41, 37.23, 44.92, 45.75, 47.7, 44.87, 39.04, 48.34, 53.67, 36.74, 41.1, 49.12, 50.76, 51.54, 48.77, 44.41, 46.97, 46.58, 54.62, 50.24, 55.69, 45.26, 38.86, 42.06, 46.76, 44.82, 38.06, 45.17, 44.17, 37.52, 41.47, 42.06, 44.32, 46.33, 41.04, 39.24, 40.9, 36.8, 38.24, 40.83, 43.52, 46.25, 50.51, 43.11, 43.37, 44.34, 44.69, 39.68, 53.42, 53.17, 59.05, 62.93, 55.83, 67.19, 67.99, 55.09, 64.67, 62.17, 57.02, 52.61, 51.37, 54.03, 56.95, 53.84, 54.3, 49.04, 55.66, 59.46, 56.85, 55.25, 53.56, 57.55, 57.05, 59.6, 58.43, 61.62, 65.32, 58.61, 61.51, 58.3, 51.31, 53.49, 53.62, 54.59, 55.13, 59.18, 55.75, 60.18, 60.87, 60.51, 60.56, 61.25, 58.95, 58.61, 56.97, 58.6, 58.88, 56.73, 55.16, 56.25, 61.07, 69.22, 70.17, 77.91, 75.7, 72.0, 68.12, 74.1, 70.88, 76.02, 77.12, 77.08, 71.56, 75.28, 78.54, 79.85, 77.5, 79.45, 75.66, 73.41, 76.49, 72.75, 67.35, 64.12, 64.34, 61.85, 58.85, 59.38, 57.57, 55.74, 60.98, 58.26, 56.77, 62.2, 62.53, 64.96, 63.42, 63.67, 62.08, 61.42, 64.05, 65.47, 64.67, 66.86, 65.2, 66.15, 70.24, 64.01, 63.65, 64.62, 63.63, 59.31, 59.41, 52.38, 61.73, 67.15, 61.6, 66.86, 70.78, 66.85, 65.19, 70.85, 66.51, 65.41, 69.27, 64.46, 64.6, 67.09, 73.76, 72.57, 71.32, 76.41, 74.4, 72.36, 77.29, 72.15, 68.57, 67.92, 67.69, 63.08, 57.81, 57.27, 57.82, 65.4, 64.85, 68.96, 70.5, 70.7, 70.58, 72.44, 70.51, 70.94, 71.34, 69.41, 70.56, 69.36, 76.37, 78.03, 75.29, 79.86, 76.69, 75.43, 78.34, 74.34, 74.51, 69.8, 62.07, 61.67, 63.47, 58.73, 49.56, 49.85, 43.27]
[1.0, 0.99, 0.88, 0.91, 0.84, 0.87, 0.87, 0.92, 0.91, 0.91, 0.91, 0.76, 0.98, 0.84, 0.88, 0.91, 0.9, 0.64, 0.85, 0.69, 0.86, 0.9, 0.87, 0.99, 0.94, 0.93, 0.97, 0.88, 0.97, 0.74, 0.82, 0.83, 0.69, 0.87, 0.77, 0.65, 0.82, 0.71, 0.83, 0.96, 0.91, 0.91, 0.93, 0.97, 0.91, 0.9, 0.88, 0.87, 0.89, 0.85, 0.74, 0.93, 0.74, 0.97, 0.99, 1.0, 1.0, 1.0, 0.96, 1.0, 0.97, 1.0, 1.0, 1.0, 1.0, 0.99, 0.99, 0.86, 0.99, 0.85, 0.94, 0.83, 0.89, 0.92, 0.92, 0.97, 0.99, 1.0, 0.98, 1.0, 0.98, 0.98, 0.97, 0.99, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 0.99, 1.0, 0.92, 0.97, 0.91, 0.89, 0.95, 0.94, 0.95, 0.96, 0.95, 0.94, 0.96, 0.92, 0.89, 0.95, 0.67, 0.91, 0.83, 0.85, 0.9, 0.78, 0.46, 0.64, 0.66, 0.56, 0.62, 0.58, 0.56, 0.71, 0.58, 0.66, 0.73, 0.76, 0.65, 0.87, 0.86, 0.48, 0.68, 0.76, 0.6, 0.42, 0.72, 0.62, 0.66, 0.41, 0.6, 0.56, 0.45, 0.56, 0.46, 0.69, 0.53, 0.79, 0.82, 0.63, 0.79, 0.69, 0.41, 0.25, 0.61, 0.0, 0.9, 0.67, 0.35, 0.73, 0.46, 0.77, 0.21, 0.79, 0.5, 0.45, 0.45, 0.38, 0.09, 0.6, 0.66, 0.11, 0.33, 0.62, 0.4, 0.39, 0.53, 0.27, 0.82, 0.1, 0.57, 0.03, 0.93, 0.72, 0.41, 0.6, 0.56, 0.75, 0.23, 0.54, 0.53, 0.57, 0.57, 0.45, 0.16, 0.58, 0.2, 0.13, 0.41, 0.3, 0.62, 0.44, 0.58, 0.4, 0.6, 0.59, 0.67, 0.27, 0.64, 0.17, 0.82, 0.75, 0.45, 0.96, 0.64, 0.29, 0.2, 0.18, 0.3, 0.67, 0.55, 0.52, 0.14, 0.67, 0.23, 0.07, 0.34, 0.44, 0.44, 0.38, 0.54, 0.69, 0.49, 0.51, 0.8, 0.38, 0.52, 0.02, 0.89, 0.46, 0.5, 0.53, 0.59, 0.45, 0.18, 0.21, 0.35, 0.64, 0.57, 0.45, 0.11, 0.58, 0.64, 0.12, 0.52, 0.73, 0.75, 0.65, 0.16, 0.98, 0.56, 0.41, 0.95, 0.99]
RING finger
Component of a SCF(SKP2)-like complex containing CUL1, SKP1, TRIM21 and SKP2.
SCF
null
IRF8, CALR, CUL1, FBXW11, HSPA5, IKBKB, IRF3, SKP1 , VCP,SKP2, DCP2 ,ULK1, BECN1,GABARAP, GABARAPL1, GABARAPL2 , MAP1LC3C,SQSTM1,IRF3 , NMI, IFI35 , CUL1, TRIM21
USP4, IKBKB, TRIM21, CDKN1B, IRF3, IRF8, MNI
mono, 63
null
UBE2D2, UBE2D1, UBE2E1, UBE2E2
Homotrimer
null
90.718042
0.406716
55.993182
0.692045
2,496
P19474
P01857
18641315
UbiBrowser
TRIM21
MASAARLTMMWEEVTCPICLDPFVEPVSIECGHSFCQECISQVGKGGGSVCPVCRQRFLLKNLRPNRQLANMVNNLKEISQEAREGTQGERCAVHGERLHLFCEKDGKALCWVCAQSRKHRDHAMVPLEEAAQEYQEKLQVALGELRRKQELAEKLEVEIAIKRADWKKTVETQKSRIHAEFVQQKNFLVEEEQRQLQELEKDEREQLRILGEKEAKLAQQSQALQELISELDRRCHSSALELLQEVIIVLERSESWNLKDLDITSPELRSVCHVPGLKKMLRTCAVHITLDPDTANPWLILSEDRRQVRLGDTQQSIPGNEERFDSYPMVLGAQHFHSGKHYWEVDVTGKEAWDLGVCRDSVRRKGHFLLSSKSGFWTIWLWNKQKYEAGTYPQTPLHLQVPPCQVGIFLDYEAGMVSFYNITDHGSLIYSFSECAFTGPLRPFFSPGFNDGGKNTAPLTLCPLNIGSQGSTDY
Homo sapiens
Cytoplasm, Cytoplasmic vesicle, autophagosome, Nucleus, Cytoplasm, P-body, Cytoplasm, Stress granule
Low tissue specificity
{'Ciliated cells': '3.8', 'Basal respiratory cells': '6.8', 'Club cells': '5.8', 'Ionocytes': '3.7', 'Mucus glandular cells': '4.8', 'Serous glandular cells': '2.3', 'Gastric mucus-secreting cells': '8.8', 'Proximal enterocytes': '8.9', 'Paneth cells': '3.9', 'Distal enterocytes': '8.5', 'Intestinal goblet cells': '8.4', 'Exocrine glandular cells': '-0.716', 'Basal prostatic cells': '5.4', 'Prostatic glandular cells': '5.0', 'Breast glandular cells': '0.298', 'Breast myoepithelial cells': '0.351', 'Glandular and luminal cells': '5.9', 'Secretory cells': '8.4', 'Basal keratinocytes': '3.2', 'Suprabasal keratinocytes': '2.7', 'Basal squamous epithelial cells': '6.4', 'Squamous epithelial cells': '4.3', 'Alveolar cells type 1': '0.116', 'Alveolar cells type 2': '0.115', 'Salivary duct cells': '3.0', 'Ductal cells': '0.700', 'Hepatocytes': '0.503', 'Cholangiocytes': '11.4', 'Proximal tubular cells': '0.175', 'Distal tubular cells': '0.0', 'Collecting duct cells': '5.8', 'Mesothelial cells': '0.451', 'Sertoli cells': '0.479', 'Granulosa cells': '4.8', 'Enteroendocrine cells': '3.7', 'Pancreatic endocrine cells': '3.4', 'Leydig cells': '0.632', 'Excitatory neurons': '0.2', 'Inhibitory neurons': '0.1', 'Cone photoreceptor cells': '0.0', 'Rod photoreceptor cells': '0.0', 'Bipolar cells': '0.7', 'Horizontal cells': '0.6', 'Astrocytes': '0.0', 'Oligodendrocyte precursor cells': '0.9', 'Oligodendrocytes': '0.1', 'Microglial cells': '1.8', 'Muller glia cells': '2.4', 'Schwann cells': '0.099', 'Spermatogonia': '0.401', 'Spermatocytes': '-0.062', 'Early spermatids': '-0.578', 'Late spermatids': '-0.618', 'Oocytes': '1.5', 'Cytotrophoblasts': '6.6', 'Syncytiotrophoblasts': '9.8', 'Extravillous trophoblasts': '10.0', 'Endothelial cells': '7.8', 'Lymphatic endothelial cells': '6.9', 'Cardiomyocytes': '0.335', 'Skeletal myocytes': '-0.080', 'Smooth muscle cells': '6.3', 'Adipocytes': '8.3', 'Melanocytes': '0.101', 'Fibroblasts': '6.5', 'Peritubular cells': '0.579', 'Endometrial stromal cells': '4.5', 'Ovarian stromal cells': '6.7', 'Undifferentiated cells': '5.9', 'T-cells': '9.9', 'B-cells': '8.8', 'Plasma cells': '5.0', 'Nk-cells': '15.1', 'Granulocytes': '6.2', 'Monocytes': '7.8', 'Macrophages': '8.5', 'Hofbauer cells': '9.9', 'Kupffer cells': '10.3', 'Dendritic cells': '8.0', 'Langerhans cells': '0.466', 'Erythroid cells': '-0.084', 'Adipocytes (Subcutaneous)': '-0.368', 'Adipocytes (Visceral)': '-0.167', 'Breast glandular cells (progenitors)': '0.190', 'Adipocytes (Breast)': '-0.382', 'Colon enterocytes': '0.004', 'Colon enteroendocrine cells': '0.196', 'Enteric glia cells': '-0.129', 'Mitotic cells (Colon)': '0.005', 'Mitotic cells (Heart)': '0.486', 'Podocytes': '-0.114', 'Ascending Loop of Henle cells': '0.371', 'Intercalated cells': '-0.097', 'Cholangiocyte': '0.375', 'NK-cells (Liver)': '-0.278', 'Respiratory ciliated cells': '-0.022', 'Mitotic cells (Lung)': '0.157', 'NK-cells (Lung)': '0.110', 'B-cells (Lung)': '-0.155', 'Alpha cells': '0.333', 'Beta cells': '0.161', 'Prostate glandular cells': '-0.162', 'Prostate basal glandular cells': '0.286', 'Urothelial cells': '0.283', 'Keratinocyte (other)': '0.121', 'Keratinocyte (granular)': '-0.008', 'Hair cortex cells': '-0.113', 'Inner root sheath cells': '-0.069', 'Outer root sheath cells': '0.125', 'Sebaceous gland cells': '0.110', 'Eccrine sweat gland cells': '0.070', 'Adipocytes (Skin)': '0.019', 'Mitotic cells (Skin)': '0.236', 'Parietal cells': '-0.609', 'Chief cells': '-0.599', 'Gastric mucous cells': '-0.193', 'Gastric enteroendocrine cells': '-0.441', 'Mitotic cells (Stomach)': '0.261', 'Parafollicular cells': '-0.028', 'Thyroid glandular cells': '0.094', 'Mitotic cells (Thyroid)': '0.242', 'Adrenal cortex cells': '0.619', 'Adrenal medulla cells': '0.063', 'Mitotic cells (Adrenal gland)': '0.483', 'Minor salivary glandular cells': '0.582', 'Minor salivary gland ductal cells': '0.072', 'Minor salivary gland basal cells': '0.229', 'Mitotic cells (Minor salivary gland)': '0.376', 'Adipocytes (Minor salivary gland)': '0.211', 'Somatotropes': '-0.121', 'Lactotropes': '-0.287', 'Gonadotropes': '0.004', 'Corticotropes': '-0.352', 'Thyrotropes': '-0.054', 'Undifferentiated cells (Pituitary gland)': '0.486', 'Mitotic cells (Spleen)': '-0.016', 'Platelets': '0.115', 'Erythrocytes': '0.098', 'Hematopoietic stem cells': '0.042', 'B-cells (Spleen)': '0.028', 'NK-cells (Spleen)': '0.157', 'Amygdala excitatory': '0.1', 'Cerebellar inhibitory': '0.2', 'Cge interneuron': '0.3', 'Deep-layer corticothalamic and 6b': '0.3', 'Deep-layer intratelencephalic': '0.1', 'Deep-layer near-projecting': '0.1', 'Eccentric medium spiny neuron': '0.4', 'Hippocampal ca1-3': '0.5', 'Hippocampal ca4': '0.1', 'Hippocampal dentate gyrus': '0.3', 'Lamp5-lhx6 and chandelier': '0.3', 'Lower rhombic lip': '0.2', 'Mammillary body': '0.4', 'Medium spiny neuron': '0.6', 'Mge interneuron': '0.1', 'Midbrain-derived inhibitory': '0.6', 'Miscellaneous': '0.6', 'Splatter': '0.5', 'Thalamic excitatory': '1.3', 'Upper rhombic lip': '0.1', 'Upper-layer intratelencephalic': '0.1', 'Astrocyte': '1.5', 'Bergmann glia': '1.5', 'Central nervous system macrophage': '6.0', 'Choroid plexus epithelial cell': '2.9', 'Committed oligodendrocyte precursor': '1.0', 'Ependymal cell': '1.3', 'Oligodendrocyte': '0.1', 'Oligodendrocyte precursor cell': '2.3', 'Endothelial cell': '6.4', 'Pericyte': '5.3', 'Vascular associated smooth muscle cell': '3.1', 'Fibroblast': '5.3', 'Leukocyte': '7.4', 'Basophil': '107.0', 'Eosinophil': '312.5', 'Neutrophil': '496.9', 'Classical monocyte': '25.8', 'Non-classical monocyte': '66.1', 'Intermediate monocyte': '117.0', 'T-reg': '72.1', 'GdT-cell': '89.5', 'MAIT T-cell': '61.2', 'Memory CD4 T-cell': '76.8', 'Naive CD4 T-cell': '47.0', 'Memory CD8 T-cell': '81.1', 'Naive CD8 T-cell': '43.5', 'Memory B-cell': '50.4', 'Naive B-cell': '38.5', 'Plasmacytoid DC': '47.5', 'Myeloid DC': '92.2', 'NK-cell': '88.9', 'Total PBMC': '83.8', 'Vd2 gdTCR': '67.8', 'Memory CD4 T-cell Th1\\/Th17': '48.0', 'Memory CD4 T-cell Th17': '54.6', 'Memory CD4 T-cell Th2': '54.8', 'Non-Vd2 gdTCR': '73.7', 'Memory CD4 T-cell Th1': '58.8', 'Memory CD4 T-cell TFH': '61.9', 'Terminal effector memory CD4 T-cell': '72.8', 'Central memory CD8 T-cell': '59.9', 'Effector memory CD8 T-cell': '90.7', 'Terminal effector memory CD8 T-cell': '75.8', 'Non-switched memory B-cell': '52.6', 'Plasmablast': '62.3', 'Switched memory B-cell': '55.8', 'Exhausted memory B-cell': '52.1', 'Progenitor cell': '44.7', 'Memory T-reg': '82.4', 'Naive CD4 T-cell activated': '133.9', 'Naive CD8 T-cell activated': '163.4', 'Naive T-reg': '54.7'}
2IWG, 5JPX, 5OLM, 6FGA, 6S53, 7BBD, 8A58
{'Adipose Tissue': 21.42795099667774, 'Adrenal Gland': 16.707763565891472, 'Bladder': 21.861904761904764, 'Blood': 61.11958557588805, 'Blood Vessel': 22.62928389513109, 'Brain': 4.305000416351249, 'Breast': 20.001740740740743, 'Cervix Uteri': 26.420526315789473, 'Colon': 23.40817458279846, 'Esophagus': 21.74157577854671, 'Fallopian Tube': 25.39, 'Heart': 6.66628106852497, 'Kidney': 13.61479775280899, 'Liver': 10.388, 'Lung': 32.00464878892734, 'Muscle': 3.944284806973848, 'Nerve': 25.39305008077545, 'Ovary': 30.51811111111111, 'Pancreas': 6.808080182926829, 'Pituitary': 12.995699646643107, 'Prostate': 21.00597551020408, 'Salivary Gland': 16.434148148148147, 'Skin': 17.851811498065228, 'Small Intestine': 28.907085561497325, 'Spleen': 50.16024896265561, 'Stomach': 19.072721448467966, 'Testis': 6.377013850415512, 'Thyroid': 21.553307810107196, 'Uterus': 29.83549295774648, 'Vagina': 21.551141025641027}
IGHG1
ASTKGPSVFPLAPSSKSTSGGTAALGCLVKDYFPEPVTVSWNSGALTSGVHTFPAVLQSSGLYSLSSVVTVPSSSLGTQTYICNVNHKPSNTKVDKKVEPKSCDKTHTCPPCPAPELLGGPSVFLFPPKPKDTLMISRTPEVTCVVVDVSHEDPEVKFNWYVDGVEVHNAKTKPREEQYNSTYRVVSVLTVLHQDWLNGKEYKCKVSNKALPAPIEKTISKAKGQPREPQVYTLPPSRDELTKNQVSLTCLVKGFYPSDIAVEWESNGQPENNYKTTPPVLDSDGSFFLYSKLTVDKSRWQQGNVFSCSVMHEALHNHYTQKSLSLSPELQLEESCAEAQDGELDGLWTTITIFITLFLLSVCYSATVTFFKVKWIFSSVVDLKQTIIPDYRNMIGQGA
Homo sapiens
Secreted, Cell membrane
Group enriched (lymphoid tissue, urinary bladder)
{'Ciliated cells': '1.3', 'Basal respiratory cells': '0.0', 'Club cells': '1.0', 'Ionocytes': '0.0', 'Mucus glandular cells': '41.2', 'Serous glandular cells': '17.9', 'Gastric mucus-secreting cells': '8.8', 'Proximal enterocytes': '0.0', 'Paneth cells': '1.9', 'Distal enterocytes': '1.1', 'Intestinal goblet cells': '1.2', 'Exocrine glandular cells': '-0.084', 'Basal prostatic cells': '31.9', 'Prostatic glandular cells': '0.1', 'Breast glandular cells': '0.309', 'Breast myoepithelial cells': '0.221', 'Glandular and luminal cells': '0.0', 'Secretory cells': '2.5', 'Basal keratinocytes': '138.7', 'Suprabasal keratinocytes': '1.3', 'Basal squamous epithelial cells': '0.0', 'Squamous epithelial cells': '0.0', 'Alveolar cells type 1': '-0.078', 'Alveolar cells type 2': '0.130', 'Salivary duct cells': '0.8', 'Ductal cells': '0.263', 'Hepatocytes': '0.360', 'Cholangiocytes': '5.7', 'Proximal tubular cells': '0.293', 'Distal tubular cells': '0.0', 'Collecting duct cells': '0.0', 'Mesothelial cells': '0.260', 'Sertoli cells': '0.026', 'Granulosa cells': '0.0', 'Enteroendocrine cells': '2.2', 'Pancreatic endocrine cells': '0.0', 'Leydig cells': '0.209', 'Excitatory neurons': '0.0', 'Inhibitory neurons': '0.0', 'Cone photoreceptor cells': '0.0', 'Rod photoreceptor cells': '0.0', 'Bipolar cells': '0.0', 'Horizontal cells': '0.0', 'Astrocytes': '0.0', 'Oligodendrocyte precursor cells': '0.0', 'Oligodendrocytes': '0.0', 'Microglial cells': '0.0', 'Muller glia cells': '0.2', 'Schwann cells': '0.087', 'Spermatogonia': '0.209', 'Spermatocytes': '0.019', 'Early spermatids': '-0.164', 'Late spermatids': '-0.143', 'Oocytes': '0.0', 'Cytotrophoblasts': '0.0', 'Syncytiotrophoblasts': '0.1', 'Extravillous trophoblasts': '0.0', 'Endothelial cells': '12.9', 'Lymphatic endothelial cells': '56.3', 'Cardiomyocytes': '0.451', 'Skeletal myocytes': '0.041', 'Smooth muscle cells': '7.5', 'Adipocytes': '2.2', 'Melanocytes': '-0.049', 'Fibroblasts': '18.4', 'Peritubular cells': '0.230', 'Endometrial stromal cells': '0.1', 'Ovarian stromal cells': '0.0', 'Undifferentiated cells': '0.8', 'T-cells': '51.3', 'B-cells': '2014.2', 'Plasma cells': '12047.8', 'Nk-cells': '0.4', 'Granulocytes': '7.1', 'Monocytes': '0.9', 'Macrophages': '27.3', 'Hofbauer cells': '0.0', 'Kupffer cells': '59.2', 'Dendritic cells': '0.4', 'Langerhans cells': '0.084', 'Erythroid cells': '0.056', 'Adipocytes (Subcutaneous)': '-0.054', 'Adipocytes (Visceral)': '-0.192', 'Breast glandular cells (progenitors)': '0.159', 'Adipocytes (Breast)': '-0.259', 'Colon enterocytes': '0.280', 'Colon enteroendocrine cells': '0.066', 'Enteric glia cells': '-0.249', 'Mitotic cells (Colon)': '0.291', 'Mitotic cells (Heart)': '0.328', 'Podocytes': '-0.019', 'Ascending Loop of Henle cells': '-0.003', 'Intercalated cells': '0.046', 'Cholangiocyte': '0.382', 'NK-cells (Liver)': '-0.094', 'Respiratory ciliated cells': '0.002', 'Mitotic cells (Lung)': '0.058', 'NK-cells (Lung)': '-0.030', 'B-cells (Lung)': '0.320', 'Alpha cells': '0.280', 'Beta cells': '0.067', 'Prostate glandular cells': '-0.123', 'Prostate basal glandular cells': '0.083', 'Urothelial cells': '0.219', 'Keratinocyte (other)': '-0.243', 'Keratinocyte (granular)': '-0.195', 'Hair cortex cells': '0.041', 'Inner root sheath cells': '0.120', 'Outer root sheath cells': '0.218', 'Sebaceous gland cells': '0.283', 'Eccrine sweat gland cells': '0.137', 'Adipocytes (Skin)': '0.262', 'Mitotic cells (Skin)': '0.008', 'Parietal cells': '0.515', 'Chief cells': '0.529', 'Gastric mucous cells': '0.593', 'Gastric enteroendocrine cells': '0.528', 'Mitotic cells (Stomach)': '0.294', 'Parafollicular cells': '-0.097', 'Thyroid glandular cells': '-0.141', 'Mitotic cells (Thyroid)': '0.257', 'Adrenal cortex cells': '0.318', 'Adrenal medulla cells': '0.222', 'Mitotic cells (Adrenal gland)': '0.302', 'Minor salivary glandular cells': '0.249', 'Minor salivary gland ductal cells': '0.252', 'Minor salivary gland basal cells': '-0.289', 'Mitotic cells (Minor salivary gland)': '-0.161', 'Adipocytes (Minor salivary gland)': '0.105', 'Somatotropes': '-0.020', 'Lactotropes': '-0.042', 'Gonadotropes': '-0.026', 'Corticotropes': '-0.183', 'Thyrotropes': '-0.140', 'Undifferentiated cells (Pituitary gland)': '0.180', 'Mitotic cells (Spleen)': '0.426', 'Platelets': '0.102', 'Erythrocytes': '0.118', 'Hematopoietic stem cells': '0.212', 'B-cells (Spleen)': '-0.344', 'NK-cells (Spleen)': '-0.317', 'Amygdala excitatory': '0.0', 'Cerebellar inhibitory': '0.3', 'Cge interneuron': '0.0', 'Deep-layer corticothalamic and 6b': '0.0', 'Deep-layer intratelencephalic': '0.0', 'Deep-layer near-projecting': '0.0', 'Eccentric medium spiny neuron': '0.0', 'Hippocampal ca1-3': '0.0', 'Hippocampal ca4': '0.0', 'Hippocampal dentate gyrus': '0.0', 'Lamp5-lhx6 and chandelier': '0.0', 'Lower rhombic lip': '0.0', 'Mammillary body': '0.0', 'Medium spiny neuron': '0.0', 'Mge interneuron': '0.1', 'Midbrain-derived inhibitory': '0.0', 'Miscellaneous': '0.0', 'Splatter': '0.0', 'Thalamic excitatory': '0.0', 'Upper rhombic lip': '0.0', 'Upper-layer intratelencephalic': '0.0', 'Astrocyte': '1.1', 'Bergmann glia': '0.0', 'Central nervous system macrophage': '0.0', 'Choroid plexus epithelial cell': '0.0', 'Committed oligodendrocyte precursor': '0.0', 'Ependymal cell': '0.0', 'Oligodendrocyte': '0.0', 'Oligodendrocyte precursor cell': '0.0', 'Endothelial cell': '0.1', 'Pericyte': '0.1', 'Vascular associated smooth muscle cell': '0.0', 'Fibroblast': '0.0', 'Leukocyte': '12.0', 'Basophil': '7.5', 'Eosinophil': '0.1', 'Neutrophil': '15.6', 'Classical monocyte': '0.1', 'Non-classical monocyte': '0.1', 'Intermediate monocyte': '1.4', 'T-reg': '6.1', 'GdT-cell': '0.3', 'MAIT T-cell': '2.4', 'Memory CD4 T-cell': '0.6', 'Naive CD4 T-cell': '0.6', 'Memory CD8 T-cell': '0.3', 'Naive CD8 T-cell': '0.6', 'Memory B-cell': '768.6', 'Naive B-cell': '4.8', 'Plasmacytoid DC': '5.1', 'Myeloid DC': '1.8', 'NK-cell': '0.2', 'Total PBMC': '550.1', 'Vd2 gdTCR': '0.5', 'Memory CD4 T-cell Th1\\/Th17': '0.0', 'Memory CD4 T-cell Th17': '0.0', 'Memory CD4 T-cell Th2': '0.0', 'Non-Vd2 gdTCR': '0.3', 'Memory CD4 T-cell Th1': '0.0', 'Memory CD4 T-cell TFH': '0.5', 'Terminal effector memory CD4 T-cell': '0.1', 'Central memory CD8 T-cell': '0.4', 'Effector memory CD8 T-cell': '0.9', 'Terminal effector memory CD8 T-cell': '1.1', 'Non-switched memory B-cell': '667.8', 'Plasmablast': '59770.2', 'Switched memory B-cell': '1700.1', 'Exhausted memory B-cell': '3133.6', 'Progenitor cell': '330.4', 'Memory T-reg': '0.7', 'Naive CD4 T-cell activated': '0.0', 'Naive CD8 T-cell activated': '0.1', 'Naive T-reg': '0.5'}
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{'Adipose Tissue': 134.2874100830565, 'Adrenal Gland': 63.992507015503875, 'Bladder': 299.7919523809524, 'Blood': 400.4973345532831, 'Blood Vessel': 113.45827017228464, 'Brain': 1.983178770628312, 'Breast': 101.45040047930284, 'Cervix Uteri': 312.4572105263158, 'Colon': 84.98622890885751, 'Esophagus': 56.99545825605536, 'Fallopian Tube': 480.3211111111111, 'Heart': 14.883472276422763, 'Kidney': 212.59110224719103, 'Liver': 85.59602654867257, 'Lung': 583.8560622837371, 'Muscle': 3.3688685429638854, 'Nerve': 41.71643722132472, 'Ovary': 88.9104938888889, 'Pancreas': 11.484817713414634, 'Pituitary': 24.274555477031804, 'Prostate': 135.74716775510203, 'Salivary Gland': 181.3059086419753, 'Skin': 8.351694980652294, 'Small Intestine': 580.9069679144385, 'Spleen': 4960.149377593361, 'Stomach': 195.99327019498608, 'Testis': 9.551186426592798, 'Thyroid': 749.3528301684532, 'Uterus': 59.694309859154934, 'Vagina': 168.7698685897436}
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[64.75, 82.28, 91.34, 90.04, 92.74, 94.78, 93.08, 93.25, 92.84, 91.23, 89.54, 78.76, 74.1, 67.97, 63.1, 60.16, 53.31, 56.48, 55.55, 68.18, 80.78, 86.63, 86.29, 89.33, 90.63, 92.76, 94.73, 96.02, 96.14, 93.34, 90.65, 94.39, 95.21, 95.3, 92.96, 94.18, 95.04, 95.82, 96.54, 96.91, 95.89, 94.99, 94.02, 92.36, 95.07, 91.4, 93.32, 92.38, 91.15, 95.86, 94.73, 95.8, 94.55, 94.59, 95.65, 94.59, 92.63, 84.55, 85.21, 87.64, 87.5, 92.8, 94.23, 95.04, 96.4, 96.59, 96.76, 94.82, 93.81, 92.09, 90.27, 88.27, 84.85, 85.29, 87.03, 80.84, 78.43, 83.55, 86.12, 90.57, 91.95, 94.84, 94.55, 97.4, 97.07, 97.28, 96.96, 96.17, 94.52, 94.57, 94.76, 95.11, 96.25, 95.66, 96.38, 93.82, 91.96, 86.89, 78.98, 71.74, 63.77, 56.59, 54.38, 50.32, 51.46, 43.93, 48.93, 42.86, 48.88, 56.55, 57.53, 53.17, 61.33, 60.98, 61.58, 60.4, 60.31, 61.8, 71.9, 83.26, 92.41, 94.63, 97.13, 98.4, 98.22, 98.45, 97.66, 97.88, 96.93, 96.39, 96.36, 97.12, 95.8, 94.14, 92.59, 90.95, 93.21, 95.38, 96.5, 97.5, 98.0, 98.33, 98.69, 98.65, 98.54, 97.89, 95.71, 92.8, 94.19, 91.03, 89.42, 89.8, 92.34, 93.72, 95.82, 97.22, 97.5, 98.48, 98.47, 98.68, 98.58, 98.23, 96.89, 96.86, 97.93, 97.96, 97.73, 96.62, 95.12, 97.31, 97.81, 97.46, 96.84, 96.17, 95.0, 95.07, 93.61, 90.95, 88.22, 85.45, 85.07, 91.67, 94.32, 97.15, 97.96, 98.55, 98.56, 98.63, 98.53, 97.59, 95.92, 96.15, 95.44, 94.35, 96.42, 96.92, 94.73, 95.03, 95.63, 97.62, 98.22, 98.52, 98.73, 98.65, 98.57, 98.4, 97.43, 96.08, 94.22, 91.44, 92.51, 91.74, 94.42, 96.31, 97.18, 97.78, 98.36, 98.26, 98.23, 97.62, 95.67, 94.81, 92.54, 93.79, 95.12, 97.12, 98.28, 98.46, 98.57, 98.51, 98.66, 98.6, 98.19, 97.98, 97.34, 96.97, 95.52, 93.92, 95.69, 96.3, 94.6, 95.02, 95.87, 96.74, 97.59, 97.39, 98.05, 98.15, 98.56, 98.68, 98.62, 98.78, 98.56, 98.29, 98.68, 98.34, 97.44, 97.74, 97.18, 97.91, 98.23, 98.25, 98.04, 98.58, 97.59, 97.12, 90.37, 91.55, 96.37, 97.42, 97.72, 95.58, 97.27, 98.27, 97.24, 98.17, 98.0, 97.8, 97.91, 98.37, 97.82, 96.43, 95.94, 95.42, 94.52, 97.91, 98.63, 98.7, 98.75, 98.63, 98.73, 98.56, 98.63, 98.32, 97.63, 97.35, 96.58, 96.01, 96.3, 95.9, 94.45, 94.46, 94.12, 95.75, 96.94, 98.09, 98.25, 98.43, 97.89, 98.4, 98.34, 98.15, 96.74, 97.37, 97.85, 95.1, 94.19, 96.7, 97.55, 97.82, 97.41, 97.93, 96.62, 95.81, 94.89, 92.74, 80.14, 72.44, 59.96, 33.55]
[0.69, 0.84, 0.55, 0.46, 0.38, 0.09, 0.4, 0.1, 0.49, 0.44, 0.37, 0.41, 0.19, 0.53, 0.72, 0.93, 0.56, 0.53, 0.79, 0.87, 0.58, 0.44, 0.04, 0.56, 0.02, 0.01, 0.0, 0.32, 0.0, 0.43, 0.22, 0.0, 0.24, 0.43, 0.52, 0.7, 0.14, 0.54, 0.19, 0.38, 0.01, 0.28, 0.74, 0.42, 0.75, 0.23, 0.72, 0.75, 0.41, 0.3, 0.55, 0.45, 0.46, 0.84, 0.28, 0.61, 0.59, 0.35, 1.0, 0.61, 0.35, 0.15, 0.2, 0.08, 0.09, 0.26, 0.0, 0.25, 0.0, 0.49, 0.05, 0.57, 0.28, 0.75, 0.19, 0.16, 0.93, 0.81, 0.64, 0.48, 0.06, 0.32, 0.0, 0.11, 0.02, 0.27, 0.0, 0.76, 0.38, 0.3, 0.81, 0.26, 0.77, 0.27, 0.69, 0.37, 0.49, 0.03, 0.61, 0.44, 0.81, 0.62, 0.71, 0.59, 0.91, 0.77, 0.74, 0.75, 0.79, 0.73, 0.88, 0.78, 0.79, 0.44, 0.46, 0.85, 0.35, 0.89, 0.77, 0.24, 0.03, 0.32, 0.07, 0.5, 0.18, 0.53, 0.59, 0.06, 0.71, 0.24, 0.17, 0.16, 0.06, 0.13, 0.31, 0.84, 0.83, 0.4, 0.6, 0.01, 0.45, 0.0, 0.25, 0.0, 0.09, 0.01, 0.3, 0.28, 0.0, 0.21, 0.39, 0.77, 0.3, 0.29, 0.74, 0.18, 0.65, 0.14, 0.17, 0.03, 0.22, 0.17, 0.53, 0.7, 0.64, 0.47, 0.27, 0.79, 0.53, 0.29, 0.74, 0.57, 0.62, 0.85, 0.57, 0.44, 0.7, 0.39, 0.98, 0.49, 0.33, 0.02, 0.16, 0.37, 0.07, 0.07, 0.01, 0.11, 0.02, 0.42, 0.07, 0.68, 0.22, 0.75, 0.2, 0.04, 0.23, 0.75, 0.37, 0.3, 0.47, 0.02, 0.29, 0.0, 0.24, 0.0, 0.3, 0.11, 0.75, 0.34, 0.12, 0.92, 0.67, 0.52, 0.25, 0.48, 0.42, 0.55, 0.17, 0.38, 0.13, 0.47, 0.8, 0.56, 0.84, 0.43, 0.4, 0.65, 0.07, 0.45, 0.1, 0.47, 0.23, 0.44, 0.66, 0.14, 0.54, 0.85, 0.73, 0.27, 0.36, 0.79, 0.66, 0.79, 0.49, 0.01, 0.18, 0.0, 0.23, 0.0, 0.17, 0.0, 0.35, 0.16, 0.0, 0.24, 0.02, 0.38, 0.29, 0.14, 0.12, 0.11, 0.35, 0.03, 0.32, 0.07, 0.75, 0.77, 0.69, 0.74, 0.13, 0.8, 0.51, 0.29, 0.79, 0.44, 0.51, 0.83, 0.37, 0.45, 0.66, 0.3, 0.99, 0.56, 0.38, 0.01, 0.19, 0.28, 0.02, 0.41, 0.0, 0.48, 0.0, 0.2, 0.02, 0.47, 0.2, 0.5, 0.26, 0.04, 0.6, 0.68, 0.45, 0.22, 0.44, 0.0, 0.07, 0.0, 0.04, 0.0, 0.05, 0.0, 0.19, 0.25, 0.08, 0.86, 0.91, 0.27, 0.45, 0.28, 0.42, 0.45, 0.55, 0.09, 0.49, 0.45, 0.88, 0.92, 0.9, 0.98]
RING finger
Component of a SCF(SKP2)-like complex containing CUL1, SKP1, TRIM21 and SKP2.
SCF
null
IRF8, CALR, CUL1, FBXW11, HSPA5, IKBKB, IRF3, SKP1 , VCP,SKP2, DCP2 ,ULK1, BECN1,GABARAP, GABARAPL1, GABARAPL2 , MAP1LC3C,SQSTM1,IRF3 , NMI, IFI35 , CUL1, TRIM21
USP4, IKBKB, TRIM21, CDKN1B, IRF3, IRF8, MNI
mono, 63
null
UBE2D2, UBE2D1, UBE2E1, UBE2E2
Homotrimer
null
90.718042
0.406716
91.473121
0.395909
1,984
P19474
P19474
16472766, E3Net
UbiNet, UbiBrowser, 31181401
TRIM21
MASAARLTMMWEEVTCPICLDPFVEPVSIECGHSFCQECISQVGKGGGSVCPVCRQRFLLKNLRPNRQLANMVNNLKEISQEAREGTQGERCAVHGERLHLFCEKDGKALCWVCAQSRKHRDHAMVPLEEAAQEYQEKLQVALGELRRKQELAEKLEVEIAIKRADWKKTVETQKSRIHAEFVQQKNFLVEEEQRQLQELEKDEREQLRILGEKEAKLAQQSQALQELISELDRRCHSSALELLQEVIIVLERSESWNLKDLDITSPELRSVCHVPGLKKMLRTCAVHITLDPDTANPWLILSEDRRQVRLGDTQQSIPGNEERFDSYPMVLGAQHFHSGKHYWEVDVTGKEAWDLGVCRDSVRRKGHFLLSSKSGFWTIWLWNKQKYEAGTYPQTPLHLQVPPCQVGIFLDYEAGMVSFYNITDHGSLIYSFSECAFTGPLRPFFSPGFNDGGKNTAPLTLCPLNIGSQGSTDY
Homo sapiens
Cytoplasm, Cytoplasmic vesicle, autophagosome, Nucleus, Cytoplasm, P-body, Cytoplasm, Stress granule
Low tissue specificity
{'Ciliated cells': '3.8', 'Basal respiratory cells': '6.8', 'Club cells': '5.8', 'Ionocytes': '3.7', 'Mucus glandular cells': '4.8', 'Serous glandular cells': '2.3', 'Gastric mucus-secreting cells': '8.8', 'Proximal enterocytes': '8.9', 'Paneth cells': '3.9', 'Distal enterocytes': '8.5', 'Intestinal goblet cells': '8.4', 'Exocrine glandular cells': '-0.716', 'Basal prostatic cells': '5.4', 'Prostatic glandular cells': '5.0', 'Breast glandular cells': '0.298', 'Breast myoepithelial cells': '0.351', 'Glandular and luminal cells': '5.9', 'Secretory cells': '8.4', 'Basal keratinocytes': '3.2', 'Suprabasal keratinocytes': '2.7', 'Basal squamous epithelial cells': '6.4', 'Squamous epithelial cells': '4.3', 'Alveolar cells type 1': '0.116', 'Alveolar cells type 2': '0.115', 'Salivary duct cells': '3.0', 'Ductal cells': '0.700', 'Hepatocytes': '0.503', 'Cholangiocytes': '11.4', 'Proximal tubular cells': '0.175', 'Distal tubular cells': '0.0', 'Collecting duct cells': '5.8', 'Mesothelial cells': '0.451', 'Sertoli cells': '0.479', 'Granulosa cells': '4.8', 'Enteroendocrine cells': '3.7', 'Pancreatic endocrine cells': '3.4', 'Leydig cells': '0.632', 'Excitatory neurons': '0.2', 'Inhibitory neurons': '0.1', 'Cone photoreceptor cells': '0.0', 'Rod photoreceptor cells': '0.0', 'Bipolar cells': '0.7', 'Horizontal cells': '0.6', 'Astrocytes': '0.0', 'Oligodendrocyte precursor cells': '0.9', 'Oligodendrocytes': '0.1', 'Microglial cells': '1.8', 'Muller glia cells': '2.4', 'Schwann cells': '0.099', 'Spermatogonia': '0.401', 'Spermatocytes': '-0.062', 'Early spermatids': '-0.578', 'Late spermatids': '-0.618', 'Oocytes': '1.5', 'Cytotrophoblasts': '6.6', 'Syncytiotrophoblasts': '9.8', 'Extravillous trophoblasts': '10.0', 'Endothelial cells': '7.8', 'Lymphatic endothelial cells': '6.9', 'Cardiomyocytes': '0.335', 'Skeletal myocytes': '-0.080', 'Smooth muscle cells': '6.3', 'Adipocytes': '8.3', 'Melanocytes': '0.101', 'Fibroblasts': '6.5', 'Peritubular cells': '0.579', 'Endometrial stromal cells': '4.5', 'Ovarian stromal cells': '6.7', 'Undifferentiated cells': '5.9', 'T-cells': '9.9', 'B-cells': '8.8', 'Plasma cells': '5.0', 'Nk-cells': '15.1', 'Granulocytes': '6.2', 'Monocytes': '7.8', 'Macrophages': '8.5', 'Hofbauer cells': '9.9', 'Kupffer cells': '10.3', 'Dendritic cells': '8.0', 'Langerhans cells': '0.466', 'Erythroid cells': '-0.084', 'Adipocytes (Subcutaneous)': '-0.368', 'Adipocytes (Visceral)': '-0.167', 'Breast glandular cells (progenitors)': '0.190', 'Adipocytes (Breast)': '-0.382', 'Colon enterocytes': '0.004', 'Colon enteroendocrine cells': '0.196', 'Enteric glia cells': '-0.129', 'Mitotic cells (Colon)': '0.005', 'Mitotic cells (Heart)': '0.486', 'Podocytes': '-0.114', 'Ascending Loop of Henle cells': '0.371', 'Intercalated cells': '-0.097', 'Cholangiocyte': '0.375', 'NK-cells (Liver)': '-0.278', 'Respiratory ciliated cells': '-0.022', 'Mitotic cells (Lung)': '0.157', 'NK-cells (Lung)': '0.110', 'B-cells (Lung)': '-0.155', 'Alpha cells': '0.333', 'Beta cells': '0.161', 'Prostate glandular cells': '-0.162', 'Prostate basal glandular cells': '0.286', 'Urothelial cells': '0.283', 'Keratinocyte (other)': '0.121', 'Keratinocyte (granular)': '-0.008', 'Hair cortex cells': '-0.113', 'Inner root sheath cells': '-0.069', 'Outer root sheath cells': '0.125', 'Sebaceous gland cells': '0.110', 'Eccrine sweat gland cells': '0.070', 'Adipocytes (Skin)': '0.019', 'Mitotic cells (Skin)': '0.236', 'Parietal cells': '-0.609', 'Chief cells': '-0.599', 'Gastric mucous cells': '-0.193', 'Gastric enteroendocrine cells': '-0.441', 'Mitotic cells (Stomach)': '0.261', 'Parafollicular cells': '-0.028', 'Thyroid glandular cells': '0.094', 'Mitotic cells (Thyroid)': '0.242', 'Adrenal cortex cells': '0.619', 'Adrenal medulla cells': '0.063', 'Mitotic cells (Adrenal gland)': '0.483', 'Minor salivary glandular cells': '0.582', 'Minor salivary gland ductal cells': '0.072', 'Minor salivary gland basal cells': '0.229', 'Mitotic cells (Minor salivary gland)': '0.376', 'Adipocytes (Minor salivary gland)': '0.211', 'Somatotropes': '-0.121', 'Lactotropes': '-0.287', 'Gonadotropes': '0.004', 'Corticotropes': '-0.352', 'Thyrotropes': '-0.054', 'Undifferentiated cells (Pituitary gland)': '0.486', 'Mitotic cells (Spleen)': '-0.016', 'Platelets': '0.115', 'Erythrocytes': '0.098', 'Hematopoietic stem cells': '0.042', 'B-cells (Spleen)': '0.028', 'NK-cells (Spleen)': '0.157', 'Amygdala excitatory': '0.1', 'Cerebellar inhibitory': '0.2', 'Cge interneuron': '0.3', 'Deep-layer corticothalamic and 6b': '0.3', 'Deep-layer intratelencephalic': '0.1', 'Deep-layer near-projecting': '0.1', 'Eccentric medium spiny neuron': '0.4', 'Hippocampal ca1-3': '0.5', 'Hippocampal ca4': '0.1', 'Hippocampal dentate gyrus': '0.3', 'Lamp5-lhx6 and chandelier': '0.3', 'Lower rhombic lip': '0.2', 'Mammillary body': '0.4', 'Medium spiny neuron': '0.6', 'Mge interneuron': '0.1', 'Midbrain-derived inhibitory': '0.6', 'Miscellaneous': '0.6', 'Splatter': '0.5', 'Thalamic excitatory': '1.3', 'Upper rhombic lip': '0.1', 'Upper-layer intratelencephalic': '0.1', 'Astrocyte': '1.5', 'Bergmann glia': '1.5', 'Central nervous system macrophage': '6.0', 'Choroid plexus epithelial cell': '2.9', 'Committed oligodendrocyte precursor': '1.0', 'Ependymal cell': '1.3', 'Oligodendrocyte': '0.1', 'Oligodendrocyte precursor cell': '2.3', 'Endothelial cell': '6.4', 'Pericyte': '5.3', 'Vascular associated smooth muscle cell': '3.1', 'Fibroblast': '5.3', 'Leukocyte': '7.4', 'Basophil': '107.0', 'Eosinophil': '312.5', 'Neutrophil': '496.9', 'Classical monocyte': '25.8', 'Non-classical monocyte': '66.1', 'Intermediate monocyte': '117.0', 'T-reg': '72.1', 'GdT-cell': '89.5', 'MAIT T-cell': '61.2', 'Memory CD4 T-cell': '76.8', 'Naive CD4 T-cell': '47.0', 'Memory CD8 T-cell': '81.1', 'Naive CD8 T-cell': '43.5', 'Memory B-cell': '50.4', 'Naive B-cell': '38.5', 'Plasmacytoid DC': '47.5', 'Myeloid DC': '92.2', 'NK-cell': '88.9', 'Total PBMC': '83.8', 'Vd2 gdTCR': '67.8', 'Memory CD4 T-cell Th1\\/Th17': '48.0', 'Memory CD4 T-cell Th17': '54.6', 'Memory CD4 T-cell Th2': '54.8', 'Non-Vd2 gdTCR': '73.7', 'Memory CD4 T-cell Th1': '58.8', 'Memory CD4 T-cell TFH': '61.9', 'Terminal effector memory CD4 T-cell': '72.8', 'Central memory CD8 T-cell': '59.9', 'Effector memory CD8 T-cell': '90.7', 'Terminal effector memory CD8 T-cell': '75.8', 'Non-switched memory B-cell': '52.6', 'Plasmablast': '62.3', 'Switched memory B-cell': '55.8', 'Exhausted memory B-cell': '52.1', 'Progenitor cell': '44.7', 'Memory T-reg': '82.4', 'Naive CD4 T-cell activated': '133.9', 'Naive CD8 T-cell activated': '163.4', 'Naive T-reg': '54.7'}
2IWG, 5JPX, 5OLM, 6FGA, 6S53, 7BBD, 8A58
{'Adipose Tissue': 21.42795099667774, 'Adrenal Gland': 16.707763565891472, 'Bladder': 21.861904761904764, 'Blood': 61.11958557588805, 'Blood Vessel': 22.62928389513109, 'Brain': 4.305000416351249, 'Breast': 20.001740740740743, 'Cervix Uteri': 26.420526315789473, 'Colon': 23.40817458279846, 'Esophagus': 21.74157577854671, 'Fallopian Tube': 25.39, 'Heart': 6.66628106852497, 'Kidney': 13.61479775280899, 'Liver': 10.388, 'Lung': 32.00464878892734, 'Muscle': 3.944284806973848, 'Nerve': 25.39305008077545, 'Ovary': 30.51811111111111, 'Pancreas': 6.808080182926829, 'Pituitary': 12.995699646643107, 'Prostate': 21.00597551020408, 'Salivary Gland': 16.434148148148147, 'Skin': 17.851811498065228, 'Small Intestine': 28.907085561497325, 'Spleen': 50.16024896265561, 'Stomach': 19.072721448467966, 'Testis': 6.377013850415512, 'Thyroid': 21.553307810107196, 'Uterus': 29.83549295774648, 'Vagina': 21.551141025641027}
TRIM21
MASAARLTMMWEEVTCPICLDPFVEPVSIECGHSFCQECISQVGKGGGSVCPVCRQRFLLKNLRPNRQLANMVNNLKEISQEAREGTQGERCAVHGERLHLFCEKDGKALCWVCAQSRKHRDHAMVPLEEAAQEYQEKLQVALGELRRKQELAEKLEVEIAIKRADWKKTVETQKSRIHAEFVQQKNFLVEEEQRQLQELEKDEREQLRILGEKEAKLAQQSQALQELISELDRRCHSSALELLQEVIIVLERSESWNLKDLDITSPELRSVCHVPGLKKMLRTCAVHITLDPDTANPWLILSEDRRQVRLGDTQQSIPGNEERFDSYPMVLGAQHFHSGKHYWEVDVTGKEAWDLGVCRDSVRRKGHFLLSSKSGFWTIWLWNKQKYEAGTYPQTPLHLQVPPCQVGIFLDYEAGMVSFYNITDHGSLIYSFSECAFTGPLRPFFSPGFNDGGKNTAPLTLCPLNIGSQGSTDY
Homo sapiens
Cytoplasm, Cytoplasmic vesicle, autophagosome, Nucleus, Cytoplasm, P-body, Cytoplasm, Stress granule
Low tissue specificity
{'Ciliated cells': '3.8', 'Basal respiratory cells': '6.8', 'Club cells': '5.8', 'Ionocytes': '3.7', 'Mucus glandular cells': '4.8', 'Serous glandular cells': '2.3', 'Gastric mucus-secreting cells': '8.8', 'Proximal enterocytes': '8.9', 'Paneth cells': '3.9', 'Distal enterocytes': '8.5', 'Intestinal goblet cells': '8.4', 'Exocrine glandular cells': '-0.716', 'Basal prostatic cells': '5.4', 'Prostatic glandular cells': '5.0', 'Breast glandular cells': '0.298', 'Breast myoepithelial cells': '0.351', 'Glandular and luminal cells': '5.9', 'Secretory cells': '8.4', 'Basal keratinocytes': '3.2', 'Suprabasal keratinocytes': '2.7', 'Basal squamous epithelial cells': '6.4', 'Squamous epithelial cells': '4.3', 'Alveolar cells type 1': '0.116', 'Alveolar cells type 2': '0.115', 'Salivary duct cells': '3.0', 'Ductal cells': '0.700', 'Hepatocytes': '0.503', 'Cholangiocytes': '11.4', 'Proximal tubular cells': '0.175', 'Distal tubular cells': '0.0', 'Collecting duct cells': '5.8', 'Mesothelial cells': '0.451', 'Sertoli cells': '0.479', 'Granulosa cells': '4.8', 'Enteroendocrine cells': '3.7', 'Pancreatic endocrine cells': '3.4', 'Leydig cells': '0.632', 'Excitatory neurons': '0.2', 'Inhibitory neurons': '0.1', 'Cone photoreceptor cells': '0.0', 'Rod photoreceptor cells': '0.0', 'Bipolar cells': '0.7', 'Horizontal cells': '0.6', 'Astrocytes': '0.0', 'Oligodendrocyte precursor cells': '0.9', 'Oligodendrocytes': '0.1', 'Microglial cells': '1.8', 'Muller glia cells': '2.4', 'Schwann cells': '0.099', 'Spermatogonia': '0.401', 'Spermatocytes': '-0.062', 'Early spermatids': '-0.578', 'Late spermatids': '-0.618', 'Oocytes': '1.5', 'Cytotrophoblasts': '6.6', 'Syncytiotrophoblasts': '9.8', 'Extravillous trophoblasts': '10.0', 'Endothelial cells': '7.8', 'Lymphatic endothelial cells': '6.9', 'Cardiomyocytes': '0.335', 'Skeletal myocytes': '-0.080', 'Smooth muscle cells': '6.3', 'Adipocytes': '8.3', 'Melanocytes': '0.101', 'Fibroblasts': '6.5', 'Peritubular cells': '0.579', 'Endometrial stromal cells': '4.5', 'Ovarian stromal cells': '6.7', 'Undifferentiated cells': '5.9', 'T-cells': '9.9', 'B-cells': '8.8', 'Plasma cells': '5.0', 'Nk-cells': '15.1', 'Granulocytes': '6.2', 'Monocytes': '7.8', 'Macrophages': '8.5', 'Hofbauer cells': '9.9', 'Kupffer cells': '10.3', 'Dendritic cells': '8.0', 'Langerhans cells': '0.466', 'Erythroid cells': '-0.084', 'Adipocytes (Subcutaneous)': '-0.368', 'Adipocytes (Visceral)': '-0.167', 'Breast glandular cells (progenitors)': '0.190', 'Adipocytes (Breast)': '-0.382', 'Colon enterocytes': '0.004', 'Colon enteroendocrine cells': '0.196', 'Enteric glia cells': '-0.129', 'Mitotic cells (Colon)': '0.005', 'Mitotic cells (Heart)': '0.486', 'Podocytes': '-0.114', 'Ascending Loop of Henle cells': '0.371', 'Intercalated cells': '-0.097', 'Cholangiocyte': '0.375', 'NK-cells (Liver)': '-0.278', 'Respiratory ciliated cells': '-0.022', 'Mitotic cells (Lung)': '0.157', 'NK-cells (Lung)': '0.110', 'B-cells (Lung)': '-0.155', 'Alpha cells': '0.333', 'Beta cells': '0.161', 'Prostate glandular cells': '-0.162', 'Prostate basal glandular cells': '0.286', 'Urothelial cells': '0.283', 'Keratinocyte (other)': '0.121', 'Keratinocyte (granular)': '-0.008', 'Hair cortex cells': '-0.113', 'Inner root sheath cells': '-0.069', 'Outer root sheath cells': '0.125', 'Sebaceous gland cells': '0.110', 'Eccrine sweat gland cells': '0.070', 'Adipocytes (Skin)': '0.019', 'Mitotic cells (Skin)': '0.236', 'Parietal cells': '-0.609', 'Chief cells': '-0.599', 'Gastric mucous cells': '-0.193', 'Gastric enteroendocrine cells': '-0.441', 'Mitotic cells (Stomach)': '0.261', 'Parafollicular cells': '-0.028', 'Thyroid glandular cells': '0.094', 'Mitotic cells (Thyroid)': '0.242', 'Adrenal cortex cells': '0.619', 'Adrenal medulla cells': '0.063', 'Mitotic cells (Adrenal gland)': '0.483', 'Minor salivary glandular cells': '0.582', 'Minor salivary gland ductal cells': '0.072', 'Minor salivary gland basal cells': '0.229', 'Mitotic cells (Minor salivary gland)': '0.376', 'Adipocytes (Minor salivary gland)': '0.211', 'Somatotropes': '-0.121', 'Lactotropes': '-0.287', 'Gonadotropes': '0.004', 'Corticotropes': '-0.352', 'Thyrotropes': '-0.054', 'Undifferentiated cells (Pituitary gland)': '0.486', 'Mitotic cells (Spleen)': '-0.016', 'Platelets': '0.115', 'Erythrocytes': '0.098', 'Hematopoietic stem cells': '0.042', 'B-cells (Spleen)': '0.028', 'NK-cells (Spleen)': '0.157', 'Amygdala excitatory': '0.1', 'Cerebellar inhibitory': '0.2', 'Cge interneuron': '0.3', 'Deep-layer corticothalamic and 6b': '0.3', 'Deep-layer intratelencephalic': '0.1', 'Deep-layer near-projecting': '0.1', 'Eccentric medium spiny neuron': '0.4', 'Hippocampal ca1-3': '0.5', 'Hippocampal ca4': '0.1', 'Hippocampal dentate gyrus': '0.3', 'Lamp5-lhx6 and chandelier': '0.3', 'Lower rhombic lip': '0.2', 'Mammillary body': '0.4', 'Medium spiny neuron': '0.6', 'Mge interneuron': '0.1', 'Midbrain-derived inhibitory': '0.6', 'Miscellaneous': '0.6', 'Splatter': '0.5', 'Thalamic excitatory': '1.3', 'Upper rhombic lip': '0.1', 'Upper-layer intratelencephalic': '0.1', 'Astrocyte': '1.5', 'Bergmann glia': '1.5', 'Central nervous system macrophage': '6.0', 'Choroid plexus epithelial cell': '2.9', 'Committed oligodendrocyte precursor': '1.0', 'Ependymal cell': '1.3', 'Oligodendrocyte': '0.1', 'Oligodendrocyte precursor cell': '2.3', 'Endothelial cell': '6.4', 'Pericyte': '5.3', 'Vascular associated smooth muscle cell': '3.1', 'Fibroblast': '5.3', 'Leukocyte': '7.4', 'Basophil': '107.0', 'Eosinophil': '312.5', 'Neutrophil': '496.9', 'Classical monocyte': '25.8', 'Non-classical monocyte': '66.1', 'Intermediate monocyte': '117.0', 'T-reg': '72.1', 'GdT-cell': '89.5', 'MAIT T-cell': '61.2', 'Memory CD4 T-cell': '76.8', 'Naive CD4 T-cell': '47.0', 'Memory CD8 T-cell': '81.1', 'Naive CD8 T-cell': '43.5', 'Memory B-cell': '50.4', 'Naive B-cell': '38.5', 'Plasmacytoid DC': '47.5', 'Myeloid DC': '92.2', 'NK-cell': '88.9', 'Total PBMC': '83.8', 'Vd2 gdTCR': '67.8', 'Memory CD4 T-cell Th1\\/Th17': '48.0', 'Memory CD4 T-cell Th17': '54.6', 'Memory CD4 T-cell Th2': '54.8', 'Non-Vd2 gdTCR': '73.7', 'Memory CD4 T-cell Th1': '58.8', 'Memory CD4 T-cell TFH': '61.9', 'Terminal effector memory CD4 T-cell': '72.8', 'Central memory CD8 T-cell': '59.9', 'Effector memory CD8 T-cell': '90.7', 'Terminal effector memory CD8 T-cell': '75.8', 'Non-switched memory B-cell': '52.6', 'Plasmablast': '62.3', 'Switched memory B-cell': '55.8', 'Exhausted memory B-cell': '52.1', 'Progenitor cell': '44.7', 'Memory T-reg': '82.4', 'Naive CD4 T-cell activated': '133.9', 'Naive CD8 T-cell activated': '163.4', 'Naive T-reg': '54.7'}
2IWG, 5JPX, 5OLM, 6FGA, 6S53, 7BBD, 8A58
{'Adipose Tissue': 21.42795099667774, 'Adrenal Gland': 16.707763565891472, 'Bladder': 21.861904761904764, 'Blood': 61.11958557588805, 'Blood Vessel': 22.62928389513109, 'Brain': 4.305000416351249, 'Breast': 20.001740740740743, 'Cervix Uteri': 26.420526315789473, 'Colon': 23.40817458279846, 'Esophagus': 21.74157577854671, 'Fallopian Tube': 25.39, 'Heart': 6.66628106852497, 'Kidney': 13.61479775280899, 'Liver': 10.388, 'Lung': 32.00464878892734, 'Muscle': 3.944284806973848, 'Nerve': 25.39305008077545, 'Ovary': 30.51811111111111, 'Pancreas': 6.808080182926829, 'Pituitary': 12.995699646643107, 'Prostate': 21.00597551020408, 'Salivary Gland': 16.434148148148147, 'Skin': 17.851811498065228, 'Small Intestine': 28.907085561497325, 'Spleen': 50.16024896265561, 'Stomach': 19.072721448467966, 'Testis': 6.377013850415512, 'Thyroid': 21.553307810107196, 'Uterus': 29.83549295774648, 'Vagina': 21.551141025641027}
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RING finger
Component of a SCF(SKP2)-like complex containing CUL1, SKP1, TRIM21 and SKP2.
SCF
null
IRF8, CALR, CUL1, FBXW11, HSPA5, IKBKB, IRF3, SKP1 , VCP,SKP2, DCP2 ,ULK1, BECN1,GABARAP, GABARAPL1, GABARAPL2 , MAP1LC3C,SQSTM1,IRF3 , NMI, IFI35 , CUL1, TRIM21
USP4, IKBKB, TRIM21, CDKN1B, IRF3, IRF8, MNI
mono, 63
null
UBE2D2, UBE2D1, UBE2E1, UBE2E2
Homotrimer
null
90.718042
0.406716
90.718042
0.406716
1,674
P19474
P34897
30367038
UbiBrowser
TRIM21
MASAARLTMMWEEVTCPICLDPFVEPVSIECGHSFCQECISQVGKGGGSVCPVCRQRFLLKNLRPNRQLANMVNNLKEISQEAREGTQGERCAVHGERLHLFCEKDGKALCWVCAQSRKHRDHAMVPLEEAAQEYQEKLQVALGELRRKQELAEKLEVEIAIKRADWKKTVETQKSRIHAEFVQQKNFLVEEEQRQLQELEKDEREQLRILGEKEAKLAQQSQALQELISELDRRCHSSALELLQEVIIVLERSESWNLKDLDITSPELRSVCHVPGLKKMLRTCAVHITLDPDTANPWLILSEDRRQVRLGDTQQSIPGNEERFDSYPMVLGAQHFHSGKHYWEVDVTGKEAWDLGVCRDSVRRKGHFLLSSKSGFWTIWLWNKQKYEAGTYPQTPLHLQVPPCQVGIFLDYEAGMVSFYNITDHGSLIYSFSECAFTGPLRPFFSPGFNDGGKNTAPLTLCPLNIGSQGSTDY
Homo sapiens
Cytoplasm, Cytoplasmic vesicle, autophagosome, Nucleus, Cytoplasm, P-body, Cytoplasm, Stress granule
Low tissue specificity
{'Ciliated cells': '3.8', 'Basal respiratory cells': '6.8', 'Club cells': '5.8', 'Ionocytes': '3.7', 'Mucus glandular cells': '4.8', 'Serous glandular cells': '2.3', 'Gastric mucus-secreting cells': '8.8', 'Proximal enterocytes': '8.9', 'Paneth cells': '3.9', 'Distal enterocytes': '8.5', 'Intestinal goblet cells': '8.4', 'Exocrine glandular cells': '-0.716', 'Basal prostatic cells': '5.4', 'Prostatic glandular cells': '5.0', 'Breast glandular cells': '0.298', 'Breast myoepithelial cells': '0.351', 'Glandular and luminal cells': '5.9', 'Secretory cells': '8.4', 'Basal keratinocytes': '3.2', 'Suprabasal keratinocytes': '2.7', 'Basal squamous epithelial cells': '6.4', 'Squamous epithelial cells': '4.3', 'Alveolar cells type 1': '0.116', 'Alveolar cells type 2': '0.115', 'Salivary duct cells': '3.0', 'Ductal cells': '0.700', 'Hepatocytes': '0.503', 'Cholangiocytes': '11.4', 'Proximal tubular cells': '0.175', 'Distal tubular cells': '0.0', 'Collecting duct cells': '5.8', 'Mesothelial cells': '0.451', 'Sertoli cells': '0.479', 'Granulosa cells': '4.8', 'Enteroendocrine cells': '3.7', 'Pancreatic endocrine cells': '3.4', 'Leydig cells': '0.632', 'Excitatory neurons': '0.2', 'Inhibitory neurons': '0.1', 'Cone photoreceptor cells': '0.0', 'Rod photoreceptor cells': '0.0', 'Bipolar cells': '0.7', 'Horizontal cells': '0.6', 'Astrocytes': '0.0', 'Oligodendrocyte precursor cells': '0.9', 'Oligodendrocytes': '0.1', 'Microglial cells': '1.8', 'Muller glia cells': '2.4', 'Schwann cells': '0.099', 'Spermatogonia': '0.401', 'Spermatocytes': '-0.062', 'Early spermatids': '-0.578', 'Late spermatids': '-0.618', 'Oocytes': '1.5', 'Cytotrophoblasts': '6.6', 'Syncytiotrophoblasts': '9.8', 'Extravillous trophoblasts': '10.0', 'Endothelial cells': '7.8', 'Lymphatic endothelial cells': '6.9', 'Cardiomyocytes': '0.335', 'Skeletal myocytes': '-0.080', 'Smooth muscle cells': '6.3', 'Adipocytes': '8.3', 'Melanocytes': '0.101', 'Fibroblasts': '6.5', 'Peritubular cells': '0.579', 'Endometrial stromal cells': '4.5', 'Ovarian stromal cells': '6.7', 'Undifferentiated cells': '5.9', 'T-cells': '9.9', 'B-cells': '8.8', 'Plasma cells': '5.0', 'Nk-cells': '15.1', 'Granulocytes': '6.2', 'Monocytes': '7.8', 'Macrophages': '8.5', 'Hofbauer cells': '9.9', 'Kupffer cells': '10.3', 'Dendritic cells': '8.0', 'Langerhans cells': '0.466', 'Erythroid cells': '-0.084', 'Adipocytes (Subcutaneous)': '-0.368', 'Adipocytes (Visceral)': '-0.167', 'Breast glandular cells (progenitors)': '0.190', 'Adipocytes (Breast)': '-0.382', 'Colon enterocytes': '0.004', 'Colon enteroendocrine cells': '0.196', 'Enteric glia cells': '-0.129', 'Mitotic cells (Colon)': '0.005', 'Mitotic cells (Heart)': '0.486', 'Podocytes': '-0.114', 'Ascending Loop of Henle cells': '0.371', 'Intercalated cells': '-0.097', 'Cholangiocyte': '0.375', 'NK-cells (Liver)': '-0.278', 'Respiratory ciliated cells': '-0.022', 'Mitotic cells (Lung)': '0.157', 'NK-cells (Lung)': '0.110', 'B-cells (Lung)': '-0.155', 'Alpha cells': '0.333', 'Beta cells': '0.161', 'Prostate glandular cells': '-0.162', 'Prostate basal glandular cells': '0.286', 'Urothelial cells': '0.283', 'Keratinocyte (other)': '0.121', 'Keratinocyte (granular)': '-0.008', 'Hair cortex cells': '-0.113', 'Inner root sheath cells': '-0.069', 'Outer root sheath cells': '0.125', 'Sebaceous gland cells': '0.110', 'Eccrine sweat gland cells': '0.070', 'Adipocytes (Skin)': '0.019', 'Mitotic cells (Skin)': '0.236', 'Parietal cells': '-0.609', 'Chief cells': '-0.599', 'Gastric mucous cells': '-0.193', 'Gastric enteroendocrine cells': '-0.441', 'Mitotic cells (Stomach)': '0.261', 'Parafollicular cells': '-0.028', 'Thyroid glandular cells': '0.094', 'Mitotic cells (Thyroid)': '0.242', 'Adrenal cortex cells': '0.619', 'Adrenal medulla cells': '0.063', 'Mitotic cells (Adrenal gland)': '0.483', 'Minor salivary glandular cells': '0.582', 'Minor salivary gland ductal cells': '0.072', 'Minor salivary gland basal cells': '0.229', 'Mitotic cells (Minor salivary gland)': '0.376', 'Adipocytes (Minor salivary gland)': '0.211', 'Somatotropes': '-0.121', 'Lactotropes': '-0.287', 'Gonadotropes': '0.004', 'Corticotropes': '-0.352', 'Thyrotropes': '-0.054', 'Undifferentiated cells (Pituitary gland)': '0.486', 'Mitotic cells (Spleen)': '-0.016', 'Platelets': '0.115', 'Erythrocytes': '0.098', 'Hematopoietic stem cells': '0.042', 'B-cells (Spleen)': '0.028', 'NK-cells (Spleen)': '0.157', 'Amygdala excitatory': '0.1', 'Cerebellar inhibitory': '0.2', 'Cge interneuron': '0.3', 'Deep-layer corticothalamic and 6b': '0.3', 'Deep-layer intratelencephalic': '0.1', 'Deep-layer near-projecting': '0.1', 'Eccentric medium spiny neuron': '0.4', 'Hippocampal ca1-3': '0.5', 'Hippocampal ca4': '0.1', 'Hippocampal dentate gyrus': '0.3', 'Lamp5-lhx6 and chandelier': '0.3', 'Lower rhombic lip': '0.2', 'Mammillary body': '0.4', 'Medium spiny neuron': '0.6', 'Mge interneuron': '0.1', 'Midbrain-derived inhibitory': '0.6', 'Miscellaneous': '0.6', 'Splatter': '0.5', 'Thalamic excitatory': '1.3', 'Upper rhombic lip': '0.1', 'Upper-layer intratelencephalic': '0.1', 'Astrocyte': '1.5', 'Bergmann glia': '1.5', 'Central nervous system macrophage': '6.0', 'Choroid plexus epithelial cell': '2.9', 'Committed oligodendrocyte precursor': '1.0', 'Ependymal cell': '1.3', 'Oligodendrocyte': '0.1', 'Oligodendrocyte precursor cell': '2.3', 'Endothelial cell': '6.4', 'Pericyte': '5.3', 'Vascular associated smooth muscle cell': '3.1', 'Fibroblast': '5.3', 'Leukocyte': '7.4', 'Basophil': '107.0', 'Eosinophil': '312.5', 'Neutrophil': '496.9', 'Classical monocyte': '25.8', 'Non-classical monocyte': '66.1', 'Intermediate monocyte': '117.0', 'T-reg': '72.1', 'GdT-cell': '89.5', 'MAIT T-cell': '61.2', 'Memory CD4 T-cell': '76.8', 'Naive CD4 T-cell': '47.0', 'Memory CD8 T-cell': '81.1', 'Naive CD8 T-cell': '43.5', 'Memory B-cell': '50.4', 'Naive B-cell': '38.5', 'Plasmacytoid DC': '47.5', 'Myeloid DC': '92.2', 'NK-cell': '88.9', 'Total PBMC': '83.8', 'Vd2 gdTCR': '67.8', 'Memory CD4 T-cell Th1\\/Th17': '48.0', 'Memory CD4 T-cell Th17': '54.6', 'Memory CD4 T-cell Th2': '54.8', 'Non-Vd2 gdTCR': '73.7', 'Memory CD4 T-cell Th1': '58.8', 'Memory CD4 T-cell TFH': '61.9', 'Terminal effector memory CD4 T-cell': '72.8', 'Central memory CD8 T-cell': '59.9', 'Effector memory CD8 T-cell': '90.7', 'Terminal effector memory CD8 T-cell': '75.8', 'Non-switched memory B-cell': '52.6', 'Plasmablast': '62.3', 'Switched memory B-cell': '55.8', 'Exhausted memory B-cell': '52.1', 'Progenitor cell': '44.7', 'Memory T-reg': '82.4', 'Naive CD4 T-cell activated': '133.9', 'Naive CD8 T-cell activated': '163.4', 'Naive T-reg': '54.7'}
2IWG, 5JPX, 5OLM, 6FGA, 6S53, 7BBD, 8A58
{'Adipose Tissue': 21.42795099667774, 'Adrenal Gland': 16.707763565891472, 'Bladder': 21.861904761904764, 'Blood': 61.11958557588805, 'Blood Vessel': 22.62928389513109, 'Brain': 4.305000416351249, 'Breast': 20.001740740740743, 'Cervix Uteri': 26.420526315789473, 'Colon': 23.40817458279846, 'Esophagus': 21.74157577854671, 'Fallopian Tube': 25.39, 'Heart': 6.66628106852497, 'Kidney': 13.61479775280899, 'Liver': 10.388, 'Lung': 32.00464878892734, 'Muscle': 3.944284806973848, 'Nerve': 25.39305008077545, 'Ovary': 30.51811111111111, 'Pancreas': 6.808080182926829, 'Pituitary': 12.995699646643107, 'Prostate': 21.00597551020408, 'Salivary Gland': 16.434148148148147, 'Skin': 17.851811498065228, 'Small Intestine': 28.907085561497325, 'Spleen': 50.16024896265561, 'Stomach': 19.072721448467966, 'Testis': 6.377013850415512, 'Thyroid': 21.553307810107196, 'Uterus': 29.83549295774648, 'Vagina': 21.551141025641027}
SHMT2
MLYFSLFWAARPLQRCGQLVRMAIRAQHSNAAQTQTGEANRGWTGQESLSDSDPEMWELLQREKDRQCRGLELIASENFCSRAALEALGSCLNNKYSEGYPGKRYYGGAEVVDEIELLCQRRALEAFDLDPAQWGVNVQPYSGSPANLAVYTALLQPHDRIMGLDLPDGGHLTHGYMSDVKRISATSIFFESMPYKLNPKTGLIDYNQLALTARLFRPRLIIAGTSAYARLIDYARMREVCDEVKAHLLADMAHISGLVAAKVIPSPFKHADIVTTTTHKTLRGARSGLIFYRKGVKAVDPKTGREIPYTFEDRINFAVFPSLQGGPHNHAIAAVAVALKQACTPMFREYSLQVLKNARAMADALLERGYSLVSGGTDNHLVLVDLRPKGLDGARAERVLELVSITANKNTCPGDRSAITPGGLRLGAPALTSRQFREDDFRRVVDFIDEGVNIGLEVKSKTAKLQDFKSFLLKDSETSQRLANLRQRVEQFARAFPMPGFDEH
Homo sapiens
Mitochondrion, Mitochondrion matrix, mitochondrion nucleoid, Mitochondrion inner membrane, Cytoplasm, Nucleus
Tissue enhanced (liver)
{'Ciliated cells': '10.1', 'Basal respiratory cells': '42.5', 'Club cells': '21.1', 'Ionocytes': '21.7', 'Mucus glandular cells': '15.7', 'Serous glandular cells': '24.8', 'Gastric mucus-secreting cells': '24.2', 'Proximal enterocytes': '14.5', 'Paneth cells': '21.0', 'Distal enterocytes': '11.0', 'Intestinal goblet cells': '18.8', 'Exocrine glandular cells': '-0.671', 'Basal prostatic cells': '9.8', 'Prostatic glandular cells': '12.7', 'Breast glandular cells': '0.330', 'Breast myoepithelial cells': '0.012', 'Glandular and luminal cells': '11.6', 'Secretory cells': '27.0', 'Basal keratinocytes': '38.1', 'Suprabasal keratinocytes': '33.1', 'Basal squamous epithelial cells': '54.5', 'Squamous epithelial cells': '46.2', 'Alveolar cells type 1': '-0.337', 'Alveolar cells type 2': '0.171', 'Salivary duct cells': '20.5', 'Ductal cells': '0.366', 'Hepatocytes': '0.421', 'Cholangiocytes': '21.0', 'Proximal tubular cells': '0.363', 'Distal tubular cells': '3.1', 'Collecting duct cells': '5.8', 'Mesothelial cells': '0.272', 'Sertoli cells': '0.597', 'Granulosa cells': '20.8', 'Enteroendocrine cells': '17.5', 'Pancreatic endocrine cells': '49.2', 'Leydig cells': '0.688', 'Excitatory neurons': '3.6', 'Inhibitory neurons': '3.1', 'Cone photoreceptor cells': '5.1', 'Rod photoreceptor cells': '2.2', 'Bipolar cells': '7.1', 'Horizontal cells': '7.6', 'Astrocytes': '4.0', 'Oligodendrocyte precursor cells': '3.8', 'Oligodendrocytes': '2.2', 'Microglial cells': '3.6', 'Muller glia cells': '46.0', 'Schwann cells': '0.006', 'Spermatogonia': '0.447', 'Spermatocytes': '-0.011', 'Early spermatids': '-0.618', 'Late spermatids': '-0.692', 'Oocytes': '21.3', 'Cytotrophoblasts': '57.1', 'Syncytiotrophoblasts': '34.1', 'Extravillous trophoblasts': '49.6', 'Endothelial cells': '16.3', 'Lymphatic endothelial cells': '8.4', 'Cardiomyocytes': '0.461', 'Skeletal myocytes': '-0.339', 'Smooth muscle cells': '23.2', 'Adipocytes': '9.2', 'Melanocytes': '0.183', 'Fibroblasts': '31.0', 'Peritubular cells': '0.535', 'Endometrial stromal cells': '23.0', 'Ovarian stromal cells': '17.8', 'Undifferentiated cells': '58.5', 'T-cells': '20.0', 'B-cells': '49.8', 'Plasma cells': '90.5', 'Nk-cells': '16.8', 'Granulocytes': '23.6', 'Monocytes': '21.5', 'Macrophages': '22.5', 'Hofbauer cells': '44.2', 'Kupffer cells': '34.9', 'Dendritic cells': '11.1', 'Langerhans cells': '0.031', 'Erythroid cells': '-0.026', 'Adipocytes (Subcutaneous)': '-0.158', 'Adipocytes (Visceral)': '-0.204', 'Breast glandular cells (progenitors)': '0.213', 'Adipocytes (Breast)': '-0.182', 'Colon enterocytes': '0.117', 'Colon enteroendocrine cells': '-0.013', 'Enteric glia cells': '-0.295', 'Mitotic cells (Colon)': '0.293', 'Mitotic cells (Heart)': '0.505', 'Podocytes': '0.054', 'Ascending Loop of Henle cells': '0.232', 'Intercalated cells': '0.012', 'Cholangiocyte': '0.237', 'NK-cells (Liver)': '-0.401', 'Respiratory ciliated cells': '-0.135', 'Mitotic cells (Lung)': '0.341', 'NK-cells (Lung)': '-0.365', 'B-cells (Lung)': '-0.223', 'Alpha cells': '0.252', 'Beta cells': '0.097', 'Prostate glandular cells': '0.043', 'Prostate basal glandular cells': '0.380', 'Urothelial cells': '0.265', 'Keratinocyte (other)': '0.163', 'Keratinocyte (granular)': '-0.231', 'Hair cortex cells': '0.110', 'Inner root sheath cells': '0.176', 'Outer root sheath cells': '0.197', 'Sebaceous gland cells': '-0.025', 'Eccrine sweat gland cells': '-0.068', 'Adipocytes (Skin)': '-0.155', 'Mitotic cells (Skin)': '0.415', 'Parietal cells': '0.200', 'Chief cells': '0.535', 'Gastric mucous cells': '0.430', 'Gastric enteroendocrine cells': '0.443', 'Mitotic cells (Stomach)': '0.415', 'Parafollicular cells': '-0.051', 'Thyroid glandular cells': '0.022', 'Mitotic cells (Thyroid)': '0.199', 'Adrenal cortex cells': '0.451', 'Adrenal medulla cells': '-0.008', 'Mitotic cells (Adrenal gland)': '0.487', 'Minor salivary glandular cells': '0.287', 'Minor salivary gland ductal cells': '-0.043', 'Minor salivary gland basal cells': '0.168', 'Mitotic cells (Minor salivary gland)': '0.228', 'Adipocytes (Minor salivary gland)': '-0.047', 'Somatotropes': '0.377', 'Lactotropes': '0.065', 'Gonadotropes': '-0.180', 'Corticotropes': '-0.137', 'Thyrotropes': '-0.084', 'Undifferentiated cells (Pituitary gland)': '-0.196', 'Mitotic cells (Spleen)': '0.247', 'Platelets': '-0.026', 'Erythrocytes': '-0.054', 'Hematopoietic stem cells': '-0.074', 'B-cells (Spleen)': '0.258', 'NK-cells (Spleen)': '-0.095', 'Amygdala excitatory': '4.5', 'Cerebellar inhibitory': '7.3', 'Cge interneuron': '3.5', 'Deep-layer corticothalamic and 6b': '4.4', 'Deep-layer intratelencephalic': '4.3', 'Deep-layer near-projecting': '3.2', 'Eccentric medium spiny neuron': '3.5', 'Hippocampal ca1-3': '4.8', 'Hippocampal ca4': '10.7', 'Hippocampal dentate gyrus': '8.4', 'Lamp5-lhx6 and chandelier': '4.4', 'Lower rhombic lip': '5.6', 'Mammillary body': '4.5', 'Medium spiny neuron': '1.6', 'Mge interneuron': '4.1', 'Midbrain-derived inhibitory': '7.5', 'Miscellaneous': '4.2', 'Splatter': '4.4', 'Thalamic excitatory': '7.0', 'Upper rhombic lip': '8.8', 'Upper-layer intratelencephalic': '3.7', 'Astrocyte': '4.5', 'Bergmann glia': '3.8', 'Central nervous system macrophage': '4.0', 'Choroid plexus epithelial cell': '4.6', 'Committed oligodendrocyte precursor': '6.8', 'Ependymal cell': '2.7', 'Oligodendrocyte': '3.5', 'Oligodendrocyte precursor cell': '4.9', 'Endothelial cell': '2.7', 'Pericyte': '16.2', 'Vascular associated smooth muscle cell': '9.5', 'Fibroblast': '8.0', 'Leukocyte': '7.1', 'Basophil': '17.6', 'Eosinophil': '23.4', 'Neutrophil': '0.5', 'Classical monocyte': '26.2', 'Non-classical monocyte': '28.9', 'Intermediate monocyte': '57.6', 'T-reg': '114.3', 'GdT-cell': '26.7', 'MAIT T-cell': '43.4', 'Memory CD4 T-cell': '46.4', 'Naive CD4 T-cell': '18.5', 'Memory CD8 T-cell': '29.4', 'Naive CD8 T-cell': '18.7', 'Memory B-cell': '127.9', 'Naive B-cell': '46.5', 'Plasmacytoid DC': '44.1', 'Myeloid DC': '78.6', 'NK-cell': '26.5', 'Total PBMC': '55.4', 'Vd2 gdTCR': '34.5', 'Memory CD4 T-cell Th1\\/Th17': '20.2', 'Memory CD4 T-cell Th17': '30.6', 'Memory CD4 T-cell Th2': '35.8', 'Non-Vd2 gdTCR': '29.3', 'Memory CD4 T-cell Th1': '27.3', 'Memory CD4 T-cell TFH': '32.7', 'Terminal effector memory CD4 T-cell': '45.3', 'Central memory CD8 T-cell': '31.2', 'Effector memory CD8 T-cell': '50.3', 'Terminal effector memory CD8 T-cell': '30.0', 'Non-switched memory B-cell': '182.2', 'Plasmablast': '280.2', 'Switched memory B-cell': '154.8', 'Exhausted memory B-cell': '124.7', 'Progenitor cell': '70.3', 'Memory T-reg': '133.8', 'Naive CD4 T-cell activated': '115.0', 'Naive CD8 T-cell activated': '126.7', 'Naive T-reg': '98.0'}
4PVF, 5V7I, 5X3V, 6DK3, 6H3C, 6M5O, 6QVG, 6QVL, 6R8F, 7BYI, 8AQL, 8FJT, 8FJU, 8GKS, 8GKT, 8GKU, 8GKW, 8GKY, 8GKZ, 8QI7, 8SSJ, 8T4O, 8T4P, 8TLC
{'Adipose Tissue': 41.79200166112957, 'Adrenal Gland': 39.942054263565886, 'Bladder': 42.82142857142857, 'Blood': 59.88272443487621, 'Blood Vessel': 59.84358801498127, 'Brain': 18.69573656320969, 'Breast': 40.306296296296296, 'Cervix Uteri': 51.22105263157895, 'Colon': 30.582103979460847, 'Esophagus': 44.1742892733564, 'Fallopian Tube': 44.24666666666667, 'Heart': 17.698770034843204, 'Kidney': 27.562932584269664, 'Liver': 138.91194690265485, 'Lung': 54.71102076124568, 'Muscle': 26.870343711083436, 'Nerve': 42.40707592891761, 'Ovary': 47.28516666666667, 'Pancreas': 41.05201219512195, 'Pituitary': 35.560752650176674, 'Prostate': 33.38383673469388, 'Salivary Gland': 50.58327160493827, 'Skin': 101.44998894416804, 'Small Intestine': 40.0520320855615, 'Spleen': 63.16443983402489, 'Stomach': 45.96763231197772, 'Testis': 13.29124376731302, 'Thyroid': 34.37013782542113, 'Uterus': 46.38225352112675, 'Vagina': 53.108717948717945}
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[0.99, 0.97, 0.92, 0.98, 0.83, 1.0, 0.99, 0.97, 1.0, 0.88, 1.0, 0.98, 1.0, 1.0, 1.0, 0.99, 0.98, 1.0, 1.0, 1.0, 0.99, 0.91, 0.9, 0.85, 0.98, 0.89, 1.0, 0.9, 1.0, 0.88, 0.86, 0.92, 0.94, 0.8, 0.68, 0.93, 0.82, 0.61, 0.93, 0.96, 0.88, 0.7, 0.86, 0.57, 0.55, 0.85, 0.49, 0.46, 0.41, 0.42, 0.77, 0.66, 0.41, 0.53, 0.77, 0.44, 0.18, 0.57, 0.47, 0.3, 0.31, 0.64, 0.4, 0.07, 0.34, 0.34, 0.33, 0.21, 0.19, 0.1, 0.0, 0.07, 0.0, 0.15, 0.01, 0.27, 0.42, 0.21, 0.08, 0.16, 0.24, 0.49, 0.42, 0.0, 0.32, 0.44, 0.15, 0.34, 0.83, 0.32, 0.71, 0.18, 0.64, 0.8, 0.31, 0.56, 0.01, 0.13, 0.05, 0.21, 0.25, 0.77, 0.77, 0.18, 0.68, 0.52, 0.8, 0.53, 0.1, 0.68, 0.6, 0.05, 0.15, 0.66, 0.2, 0.0, 0.39, 0.34, 0.01, 0.2, 0.57, 0.23, 0.0, 0.1, 0.55, 0.06, 0.06, 0.68, 0.15, 0.46, 0.57, 0.61, 0.48, 0.04, 0.08, 0.07, 0.01, 0.01, 0.03, 0.01, 0.31, 0.3, 0.14, 0.48, 0.34, 0.0, 0.01, 0.27, 0.02, 0.0, 0.0, 0.39, 0.14, 0.09, 0.04, 0.77, 0.85, 0.6, 0.25, 0.41, 0.0, 0.0, 0.03, 0.01, 0.16, 0.28, 0.32, 0.11, 0.01, 0.06, 0.35, 0.47, 0.12, 0.01, 0.15, 0.23, 0.53, 0.43, 1.0, 0.95, 0.71, 0.42, 0.47, 0.11, 0.4, 0.05, 0.0, 0.53, 0.62, 0.05, 0.28, 0.11, 0.32, 0.46, 0.02, 0.38, 0.07, 0.34, 0.64, 0.93, 0.45, 0.06, 0.4, 0.05, 0.22, 0.16, 0.64, 0.48, 0.01, 0.06, 0.55, 0.23, 0.0, 0.46, 0.73, 0.18, 0.48, 0.02, 0.39, 0.01, 0.0, 0.0, 0.01, 0.0, 0.18, 0.13, 0.06, 0.04, 0.02, 0.23, 0.39, 0.13, 0.43, 0.08, 0.33, 0.3, 0.01, 0.18, 0.61, 0.05, 0.0, 0.48, 0.49, 0.04, 0.69, 0.1, 0.14, 0.0, 0.0, 0.0, 0.11, 0.0, 0.12, 0.06, 0.16, 0.0, 0.01, 0.02, 0.06, 0.09, 0.07, 0.55, 0.21, 0.13, 0.6, 0.23, 0.0, 0.04, 0.82, 0.35, 0.05, 0.02, 0.0, 0.0, 0.01, 0.01, 0.05, 0.01, 0.21, 0.15, 0.03, 0.02, 0.16, 0.08, 0.07, 0.74, 0.05, 0.0, 0.0, 0.0, 0.0, 0.03, 0.2, 0.32, 0.47, 0.46, 0.56, 0.48, 0.57, 0.3, 0.9, 0.95, 0.7, 0.58, 0.77, 0.66, 0.47, 0.69, 0.21, 0.56, 0.02, 0.3, 0.78, 0.33, 0.0, 0.18, 0.58, 0.03, 0.01, 0.09, 0.55, 0.53, 0.47, 0.13, 0.34, 0.13, 0.07, 0.44, 0.02, 0.17, 0.09, 0.03, 0.13, 0.0, 0.02, 0.05, 0.26, 0.03, 0.0, 0.52, 0.26, 0.04, 0.36, 0.36, 0.73, 0.6, 0.01, 0.44, 0.64, 0.09, 0.01, 0.32, 0.13, 0.02, 0.18, 0.41, 0.0, 0.0, 0.45, 0.07, 0.0, 0.02, 0.39, 0.07, 0.01, 0.41, 0.66, 0.42, 0.59, 0.04, 0.37, 0.11, 0.14, 0.22, 0.5, 0.08, 0.01, 0.32, 0.05, 0.01, 0.02, 0.0, 0.08, 0.02, 0.14, 0.01, 0.42, 0.63, 0.26, 0.42, 0.03, 0.11, 0.0, 0.04, 0.1, 0.02, 0.22, 0.25, 0.0, 0.0, 0.52, 0.23, 0.0, 0.13, 0.0, 0.27, 0.12, 0.19, 0.42, 0.15, 0.19, 0.05, 0.13, 0.72, 0.27, 0.96, 0.43, 0.64, 0.82, 0.51, 0.02, 0.04, 0.01, 0.02, 0.09, 0.0, 0.0, 0.0, 0.0, 0.01, 0.0, 0.08, 0.13, 0.01, 0.69, 0.01, 0.62, 0.29, 0.74, 0.21, 0.0, 0.35, 0.47, 0.0, 0.01, 0.28, 0.02, 0.02, 0.12, 0.32, 0.02, 0.02, 0.36, 0.03, 0.01, 0.27, 0.4, 0.01, 0.33, 0.81, 0.51, 0.2, 0.74, 0.64, 0.33, 0.71, 0.43, 0.0, 0.45, 0.47, 0.23, 0.02, 0.61, 0.84, 0.25, 0.6, 0.55, 0.06, 0.43, 0.67, 0.37, 0.05, 0.52, 0.54, 0.0, 0.4, 0.6, 0.34, 0.0, 0.12, 0.67, 0.21, 0.0, 0.47, 0.83, 0.18, 0.46, 0.21, 0.33, 0.21, 0.22, 0.83, 0.59, 0.39]
RING finger
Component of a SCF(SKP2)-like complex containing CUL1, SKP1, TRIM21 and SKP2.
SCF
null
IRF8, CALR, CUL1, FBXW11, HSPA5, IKBKB, IRF3, SKP1 , VCP,SKP2, DCP2 ,ULK1, BECN1,GABARAP, GABARAPL1, GABARAPL2 , MAP1LC3C,SQSTM1,IRF3 , NMI, IFI35 , CUL1, TRIM21
USP4, IKBKB, TRIM21, CDKN1B, IRF3, IRF8, MNI
mono, 63
null
UBE2D2, UBE2D1, UBE2E1, UBE2E2
Homotrimer
null
90.718042
0.406716
93.335833
0.328353
1,567
P19474
P35232
30886235
UbiBrowser
TRIM21
MASAARLTMMWEEVTCPICLDPFVEPVSIECGHSFCQECISQVGKGGGSVCPVCRQRFLLKNLRPNRQLANMVNNLKEISQEAREGTQGERCAVHGERLHLFCEKDGKALCWVCAQSRKHRDHAMVPLEEAAQEYQEKLQVALGELRRKQELAEKLEVEIAIKRADWKKTVETQKSRIHAEFVQQKNFLVEEEQRQLQELEKDEREQLRILGEKEAKLAQQSQALQELISELDRRCHSSALELLQEVIIVLERSESWNLKDLDITSPELRSVCHVPGLKKMLRTCAVHITLDPDTANPWLILSEDRRQVRLGDTQQSIPGNEERFDSYPMVLGAQHFHSGKHYWEVDVTGKEAWDLGVCRDSVRRKGHFLLSSKSGFWTIWLWNKQKYEAGTYPQTPLHLQVPPCQVGIFLDYEAGMVSFYNITDHGSLIYSFSECAFTGPLRPFFSPGFNDGGKNTAPLTLCPLNIGSQGSTDY
Homo sapiens
Cytoplasm, Cytoplasmic vesicle, autophagosome, Nucleus, Cytoplasm, P-body, Cytoplasm, Stress granule
Low tissue specificity
{'Ciliated cells': '3.8', 'Basal respiratory cells': '6.8', 'Club cells': '5.8', 'Ionocytes': '3.7', 'Mucus glandular cells': '4.8', 'Serous glandular cells': '2.3', 'Gastric mucus-secreting cells': '8.8', 'Proximal enterocytes': '8.9', 'Paneth cells': '3.9', 'Distal enterocytes': '8.5', 'Intestinal goblet cells': '8.4', 'Exocrine glandular cells': '-0.716', 'Basal prostatic cells': '5.4', 'Prostatic glandular cells': '5.0', 'Breast glandular cells': '0.298', 'Breast myoepithelial cells': '0.351', 'Glandular and luminal cells': '5.9', 'Secretory cells': '8.4', 'Basal keratinocytes': '3.2', 'Suprabasal keratinocytes': '2.7', 'Basal squamous epithelial cells': '6.4', 'Squamous epithelial cells': '4.3', 'Alveolar cells type 1': '0.116', 'Alveolar cells type 2': '0.115', 'Salivary duct cells': '3.0', 'Ductal cells': '0.700', 'Hepatocytes': '0.503', 'Cholangiocytes': '11.4', 'Proximal tubular cells': '0.175', 'Distal tubular cells': '0.0', 'Collecting duct cells': '5.8', 'Mesothelial cells': '0.451', 'Sertoli cells': '0.479', 'Granulosa cells': '4.8', 'Enteroendocrine cells': '3.7', 'Pancreatic endocrine cells': '3.4', 'Leydig cells': '0.632', 'Excitatory neurons': '0.2', 'Inhibitory neurons': '0.1', 'Cone photoreceptor cells': '0.0', 'Rod photoreceptor cells': '0.0', 'Bipolar cells': '0.7', 'Horizontal cells': '0.6', 'Astrocytes': '0.0', 'Oligodendrocyte precursor cells': '0.9', 'Oligodendrocytes': '0.1', 'Microglial cells': '1.8', 'Muller glia cells': '2.4', 'Schwann cells': '0.099', 'Spermatogonia': '0.401', 'Spermatocytes': '-0.062', 'Early spermatids': '-0.578', 'Late spermatids': '-0.618', 'Oocytes': '1.5', 'Cytotrophoblasts': '6.6', 'Syncytiotrophoblasts': '9.8', 'Extravillous trophoblasts': '10.0', 'Endothelial cells': '7.8', 'Lymphatic endothelial cells': '6.9', 'Cardiomyocytes': '0.335', 'Skeletal myocytes': '-0.080', 'Smooth muscle cells': '6.3', 'Adipocytes': '8.3', 'Melanocytes': '0.101', 'Fibroblasts': '6.5', 'Peritubular cells': '0.579', 'Endometrial stromal cells': '4.5', 'Ovarian stromal cells': '6.7', 'Undifferentiated cells': '5.9', 'T-cells': '9.9', 'B-cells': '8.8', 'Plasma cells': '5.0', 'Nk-cells': '15.1', 'Granulocytes': '6.2', 'Monocytes': '7.8', 'Macrophages': '8.5', 'Hofbauer cells': '9.9', 'Kupffer cells': '10.3', 'Dendritic cells': '8.0', 'Langerhans cells': '0.466', 'Erythroid cells': '-0.084', 'Adipocytes (Subcutaneous)': '-0.368', 'Adipocytes (Visceral)': '-0.167', 'Breast glandular cells (progenitors)': '0.190', 'Adipocytes (Breast)': '-0.382', 'Colon enterocytes': '0.004', 'Colon enteroendocrine cells': '0.196', 'Enteric glia cells': '-0.129', 'Mitotic cells (Colon)': '0.005', 'Mitotic cells (Heart)': '0.486', 'Podocytes': '-0.114', 'Ascending Loop of Henle cells': '0.371', 'Intercalated cells': '-0.097', 'Cholangiocyte': '0.375', 'NK-cells (Liver)': '-0.278', 'Respiratory ciliated cells': '-0.022', 'Mitotic cells (Lung)': '0.157', 'NK-cells (Lung)': '0.110', 'B-cells (Lung)': '-0.155', 'Alpha cells': '0.333', 'Beta cells': '0.161', 'Prostate glandular cells': '-0.162', 'Prostate basal glandular cells': '0.286', 'Urothelial cells': '0.283', 'Keratinocyte (other)': '0.121', 'Keratinocyte (granular)': '-0.008', 'Hair cortex cells': '-0.113', 'Inner root sheath cells': '-0.069', 'Outer root sheath cells': '0.125', 'Sebaceous gland cells': '0.110', 'Eccrine sweat gland cells': '0.070', 'Adipocytes (Skin)': '0.019', 'Mitotic cells (Skin)': '0.236', 'Parietal cells': '-0.609', 'Chief cells': '-0.599', 'Gastric mucous cells': '-0.193', 'Gastric enteroendocrine cells': '-0.441', 'Mitotic cells (Stomach)': '0.261', 'Parafollicular cells': '-0.028', 'Thyroid glandular cells': '0.094', 'Mitotic cells (Thyroid)': '0.242', 'Adrenal cortex cells': '0.619', 'Adrenal medulla cells': '0.063', 'Mitotic cells (Adrenal gland)': '0.483', 'Minor salivary glandular cells': '0.582', 'Minor salivary gland ductal cells': '0.072', 'Minor salivary gland basal cells': '0.229', 'Mitotic cells (Minor salivary gland)': '0.376', 'Adipocytes (Minor salivary gland)': '0.211', 'Somatotropes': '-0.121', 'Lactotropes': '-0.287', 'Gonadotropes': '0.004', 'Corticotropes': '-0.352', 'Thyrotropes': '-0.054', 'Undifferentiated cells (Pituitary gland)': '0.486', 'Mitotic cells (Spleen)': '-0.016', 'Platelets': '0.115', 'Erythrocytes': '0.098', 'Hematopoietic stem cells': '0.042', 'B-cells (Spleen)': '0.028', 'NK-cells (Spleen)': '0.157', 'Amygdala excitatory': '0.1', 'Cerebellar inhibitory': '0.2', 'Cge interneuron': '0.3', 'Deep-layer corticothalamic and 6b': '0.3', 'Deep-layer intratelencephalic': '0.1', 'Deep-layer near-projecting': '0.1', 'Eccentric medium spiny neuron': '0.4', 'Hippocampal ca1-3': '0.5', 'Hippocampal ca4': '0.1', 'Hippocampal dentate gyrus': '0.3', 'Lamp5-lhx6 and chandelier': '0.3', 'Lower rhombic lip': '0.2', 'Mammillary body': '0.4', 'Medium spiny neuron': '0.6', 'Mge interneuron': '0.1', 'Midbrain-derived inhibitory': '0.6', 'Miscellaneous': '0.6', 'Splatter': '0.5', 'Thalamic excitatory': '1.3', 'Upper rhombic lip': '0.1', 'Upper-layer intratelencephalic': '0.1', 'Astrocyte': '1.5', 'Bergmann glia': '1.5', 'Central nervous system macrophage': '6.0', 'Choroid plexus epithelial cell': '2.9', 'Committed oligodendrocyte precursor': '1.0', 'Ependymal cell': '1.3', 'Oligodendrocyte': '0.1', 'Oligodendrocyte precursor cell': '2.3', 'Endothelial cell': '6.4', 'Pericyte': '5.3', 'Vascular associated smooth muscle cell': '3.1', 'Fibroblast': '5.3', 'Leukocyte': '7.4', 'Basophil': '107.0', 'Eosinophil': '312.5', 'Neutrophil': '496.9', 'Classical monocyte': '25.8', 'Non-classical monocyte': '66.1', 'Intermediate monocyte': '117.0', 'T-reg': '72.1', 'GdT-cell': '89.5', 'MAIT T-cell': '61.2', 'Memory CD4 T-cell': '76.8', 'Naive CD4 T-cell': '47.0', 'Memory CD8 T-cell': '81.1', 'Naive CD8 T-cell': '43.5', 'Memory B-cell': '50.4', 'Naive B-cell': '38.5', 'Plasmacytoid DC': '47.5', 'Myeloid DC': '92.2', 'NK-cell': '88.9', 'Total PBMC': '83.8', 'Vd2 gdTCR': '67.8', 'Memory CD4 T-cell Th1\\/Th17': '48.0', 'Memory CD4 T-cell Th17': '54.6', 'Memory CD4 T-cell Th2': '54.8', 'Non-Vd2 gdTCR': '73.7', 'Memory CD4 T-cell Th1': '58.8', 'Memory CD4 T-cell TFH': '61.9', 'Terminal effector memory CD4 T-cell': '72.8', 'Central memory CD8 T-cell': '59.9', 'Effector memory CD8 T-cell': '90.7', 'Terminal effector memory CD8 T-cell': '75.8', 'Non-switched memory B-cell': '52.6', 'Plasmablast': '62.3', 'Switched memory B-cell': '55.8', 'Exhausted memory B-cell': '52.1', 'Progenitor cell': '44.7', 'Memory T-reg': '82.4', 'Naive CD4 T-cell activated': '133.9', 'Naive CD8 T-cell activated': '163.4', 'Naive T-reg': '54.7'}
2IWG, 5JPX, 5OLM, 6FGA, 6S53, 7BBD, 8A58
{'Adipose Tissue': 21.42795099667774, 'Adrenal Gland': 16.707763565891472, 'Bladder': 21.861904761904764, 'Blood': 61.11958557588805, 'Blood Vessel': 22.62928389513109, 'Brain': 4.305000416351249, 'Breast': 20.001740740740743, 'Cervix Uteri': 26.420526315789473, 'Colon': 23.40817458279846, 'Esophagus': 21.74157577854671, 'Fallopian Tube': 25.39, 'Heart': 6.66628106852497, 'Kidney': 13.61479775280899, 'Liver': 10.388, 'Lung': 32.00464878892734, 'Muscle': 3.944284806973848, 'Nerve': 25.39305008077545, 'Ovary': 30.51811111111111, 'Pancreas': 6.808080182926829, 'Pituitary': 12.995699646643107, 'Prostate': 21.00597551020408, 'Salivary Gland': 16.434148148148147, 'Skin': 17.851811498065228, 'Small Intestine': 28.907085561497325, 'Spleen': 50.16024896265561, 'Stomach': 19.072721448467966, 'Testis': 6.377013850415512, 'Thyroid': 21.553307810107196, 'Uterus': 29.83549295774648, 'Vagina': 21.551141025641027}
PHB1
MAAKVFESIGKFGLALAVAGGVVNSALYNVDAGHRAVIFDRFRGVQDIVVGEGTHFLIPWVQKPIIFDCRSRPRNVPVITGSKDLQNVNITLRILFRPVASQLPRIFTSIGEDYDERVLPSITTEILKSVVARFDAGELITQRELVSRQVSDDLTERAATFGLILDDVSLTHLTFGKEFTEAVEAKQVAQQEAERARFVVEKAEQQKKAAIISAEGDSKAAELIANSLATAGDGLIELRKLEAAEDIAYQLSRSRNITYLPAGQSVLLQLPQ
Homo sapiens
Mitochondrion inner membrane, Nucleus, Cytoplasm, Cell membrane
Low tissue specificity
{'Ciliated cells': '79.5', 'Basal respiratory cells': '177.9', 'Club cells': '124.0', 'Ionocytes': '130.0', 'Mucus glandular cells': '136.4', 'Serous glandular cells': '218.9', 'Gastric mucus-secreting cells': '71.9', 'Proximal enterocytes': '149.9', 'Paneth cells': '170.8', 'Distal enterocytes': '240.4', 'Intestinal goblet cells': '208.4', 'Exocrine glandular cells': '-0.673', 'Basal prostatic cells': '103.6', 'Prostatic glandular cells': '110.3', 'Breast glandular cells': '0.168', 'Breast myoepithelial cells': '-0.135', 'Glandular and luminal cells': '141.1', 'Secretory cells': '148.3', 'Basal keratinocytes': '129.9', 'Suprabasal keratinocytes': '139.4', 'Basal squamous epithelial cells': '77.6', 'Squamous epithelial cells': '109.2', 'Alveolar cells type 1': '-0.095', 'Alveolar cells type 2': '0.314', 'Salivary duct cells': '97.3', 'Ductal cells': '0.603', 'Hepatocytes': '0.580', 'Cholangiocytes': '95.4', 'Proximal tubular cells': '0.444', 'Distal tubular cells': '341.2', 'Collecting duct cells': '89.5', 'Mesothelial cells': '0.019', 'Sertoli cells': '0.746', 'Granulosa cells': '94.9', 'Enteroendocrine cells': '215.7', 'Pancreatic endocrine cells': '205.5', 'Leydig cells': '0.699', 'Excitatory neurons': '7.6', 'Inhibitory neurons': '9.6', 'Cone photoreceptor cells': '61.2', 'Rod photoreceptor cells': '30.9', 'Bipolar cells': '39.8', 'Horizontal cells': '29.6', 'Astrocytes': '8.4', 'Oligodendrocyte precursor cells': '10.4', 'Oligodendrocytes': '14.3', 'Microglial cells': '1.8', 'Muller glia cells': '77.0', 'Schwann cells': '-0.009', 'Spermatogonia': '0.633', 'Spermatocytes': '0.169', 'Early spermatids': '-0.570', 'Late spermatids': '-0.644', 'Oocytes': '186.0', 'Cytotrophoblasts': '252.6', 'Syncytiotrophoblasts': '143.4', 'Extravillous trophoblasts': '288.6', 'Endothelial cells': '94.5', 'Lymphatic endothelial cells': '97.9', 'Cardiomyocytes': '0.741', 'Skeletal myocytes': '-0.042', 'Smooth muscle cells': '95.9', 'Adipocytes': '85.0', 'Melanocytes': '-0.009', 'Fibroblasts': '102.2', 'Peritubular cells': '0.509', 'Endometrial stromal cells': '90.3', 'Ovarian stromal cells': '114.2', 'Undifferentiated cells': '307.8', 'T-cells': '71.9', 'B-cells': '75.4', 'Plasma cells': '119.7', 'Nk-cells': '75.8', 'Granulocytes': '87.0', 'Monocytes': '44.7', 'Macrophages': '78.2', 'Hofbauer cells': '209.3', 'Kupffer cells': '47.8', 'Dendritic cells': '214.8', 'Langerhans cells': '-0.033', 'Erythroid cells': '-0.107', 'Adipocytes (Subcutaneous)': '0.440', 'Adipocytes (Visceral)': '0.367', 'Breast glandular cells (progenitors)': '0.101', 'Adipocytes (Breast)': '0.148', 'Colon enterocytes': '0.034', 'Colon enteroendocrine cells': '0.014', 'Enteric glia cells': '-0.266', 'Mitotic cells (Colon)': '0.049', 'Mitotic cells (Heart)': '0.460', 'Podocytes': '0.061', 'Ascending Loop of Henle cells': '0.331', 'Intercalated cells': '0.184', 'Cholangiocyte': '0.356', 'NK-cells (Liver)': '-0.412', 'Respiratory ciliated cells': '-0.127', 'Mitotic cells (Lung)': '0.194', 'NK-cells (Lung)': '-0.352', 'B-cells (Lung)': '-0.356', 'Alpha cells': '0.373', 'Beta cells': '0.218', 'Prostate glandular cells': '0.142', 'Prostate basal glandular cells': '0.203', 'Urothelial cells': '-0.059', 'Keratinocyte (other)': '-0.201', 'Keratinocyte (granular)': '-0.236', 'Hair cortex cells': '0.330', 'Inner root sheath cells': '0.347', 'Outer root sheath cells': '0.339', 'Sebaceous gland cells': '0.303', 'Eccrine sweat gland cells': '0.431', 'Adipocytes (Skin)': '0.248', 'Mitotic cells (Skin)': '0.258', 'Parietal cells': '-0.381', 'Chief cells': '-0.377', 'Gastric mucous cells': '-0.080', 'Gastric enteroendocrine cells': '-0.306', 'Mitotic cells (Stomach)': '0.363', 'Parafollicular cells': '0.102', 'Thyroid glandular cells': '0.522', 'Mitotic cells (Thyroid)': '-0.023', 'Adrenal cortex cells': '0.564', 'Adrenal medulla cells': '0.000', 'Mitotic cells (Adrenal gland)': '0.421', 'Minor salivary glandular cells': '0.498', 'Minor salivary gland ductal cells': '0.283', 'Minor salivary gland basal cells': '-0.452', 'Mitotic cells (Minor salivary gland)': '-0.421', 'Adipocytes (Minor salivary gland)': '-0.215', 'Somatotropes': '-0.131', 'Lactotropes': '-0.169', 'Gonadotropes': '-0.173', 'Corticotropes': '0.151', 'Thyrotropes': '0.173', 'Undifferentiated cells (Pituitary gland)': '0.264', 'Mitotic cells (Spleen)': '0.112', 'Platelets': '0.016', 'Erythrocytes': '-0.102', 'Hematopoietic stem cells': '0.024', 'B-cells (Spleen)': '0.198', 'NK-cells (Spleen)': '-0.090', 'Amygdala excitatory': '8.3', 'Cerebellar inhibitory': '22.1', 'Cge interneuron': '17.3', 'Deep-layer corticothalamic and 6b': '12.1', 'Deep-layer intratelencephalic': '10.2', 'Deep-layer near-projecting': '15.2', 'Eccentric medium spiny neuron': '11.0', 'Hippocampal ca1-3': '11.1', 'Hippocampal ca4': '15.5', 'Hippocampal dentate gyrus': '13.7', 'Lamp5-lhx6 and chandelier': '18.6', 'Lower rhombic lip': '16.9', 'Mammillary body': '12.5', 'Medium spiny neuron': '9.6', 'Mge interneuron': '16.7', 'Midbrain-derived inhibitory': '16.4', 'Miscellaneous': '13.5', 'Splatter': '18.3', 'Thalamic excitatory': '22.7', 'Upper rhombic lip': '15.7', 'Upper-layer intratelencephalic': '10.2', 'Astrocyte': '11.0', 'Bergmann glia': '19.1', 'Central nervous system macrophage': '12.1', 'Choroid plexus epithelial cell': '20.0', 'Committed oligodendrocyte precursor': '17.4', 'Ependymal cell': '18.1', 'Oligodendrocyte': '27.4', 'Oligodendrocyte precursor cell': '18.1', 'Endothelial cell': '21.1', 'Pericyte': '23.6', 'Vascular associated smooth muscle cell': '25.5', 'Fibroblast': '15.2', 'Leukocyte': '20.4', 'Basophil': '19.9', 'Eosinophil': '13.2', 'Neutrophil': '6.9', 'Classical monocyte': '14.2', 'Non-classical monocyte': '13.9', 'Intermediate monocyte': '65.2', 'T-reg': '75.3', 'GdT-cell': '61.9', 'MAIT T-cell': '83.4', 'Memory CD4 T-cell': '56.8', 'Naive CD4 T-cell': '17.1', 'Memory CD8 T-cell': '56.3', 'Naive CD8 T-cell': '18.9', 'Memory B-cell': '61.5', 'Naive B-cell': '9.3', 'Plasmacytoid DC': '221.6', 'Myeloid DC': '93.0', 'NK-cell': '22.7', 'Total PBMC': '83.4', 'Vd2 gdTCR': '97.9', 'Memory CD4 T-cell Th1\\/Th17': '17.0', 'Memory CD4 T-cell Th17': '19.2', 'Memory CD4 T-cell Th2': '18.2', 'Non-Vd2 gdTCR': '99.0', 'Memory CD4 T-cell Th1': '19.0', 'Memory CD4 T-cell TFH': '19.9', 'Terminal effector memory CD4 T-cell': '75.8', 'Central memory CD8 T-cell': '68.5', 'Effector memory CD8 T-cell': '81.2', 'Terminal effector memory CD8 T-cell': '97.6', 'Non-switched memory B-cell': '77.9', 'Plasmablast': '79.7', 'Switched memory B-cell': '86.3', 'Exhausted memory B-cell': '68.5', 'Progenitor cell': '55.7', 'Memory T-reg': '20.1', 'Naive CD4 T-cell activated': '90.6', 'Naive CD8 T-cell activated': '97.1', 'Naive T-reg': '18.2'}
null
{}
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[57.87, 65.42, 72.52, 71.83, 77.52, 77.99, 80.46, 81.32, 83.83, 84.21, 87.35, 87.01, 88.08, 88.92, 87.51, 89.34, 88.11, 87.45, 84.96, 85.47, 84.4, 83.5, 82.38, 81.24, 81.13, 82.56, 86.36, 86.22, 88.27, 89.74, 89.35, 88.5, 89.04, 92.04, 91.58, 90.25, 90.56, 89.41, 88.59, 88.05, 84.83, 86.58, 82.89, 87.68, 86.23, 85.34, 84.05, 85.84, 88.21, 89.39, 89.02, 89.39, 91.11, 89.11, 88.5, 87.57, 86.96, 86.33, 80.81, 81.89, 86.43, 88.16, 88.28, 89.46, 89.6, 90.97, 90.88, 91.07, 90.93, 92.96, 94.01, 93.51, 94.48, 92.74, 93.95, 93.7, 94.11, 94.13, 93.27, 92.43, 92.35, 92.25, 93.25, 92.99, 89.73, 90.54, 92.5, 93.27, 93.74, 93.96, 94.19, 94.34, 94.92, 94.75, 95.44, 94.84, 94.12, 94.03, 91.95, 89.14, 89.49, 89.19, 90.1, 90.77, 90.86, 91.43, 89.98, 89.5, 89.07, 89.64, 88.34, 86.14, 88.39, 87.42, 87.44, 88.88, 87.98, 90.29, 90.46, 92.41, 92.45, 93.97, 94.17, 93.66, 94.7, 95.26, 94.31, 94.19, 94.09, 93.78, 93.52, 93.77, 94.24, 94.41, 93.16, 90.49, 88.87, 91.92, 91.38, 89.0, 90.4, 92.18, 90.66, 91.97, 92.8, 92.82, 92.94, 93.77, 94.05, 95.37, 95.03, 95.09, 95.2, 95.23, 94.53, 94.67, 94.14, 93.65, 92.56, 91.93, 91.88, 91.48, 93.61, 93.76, 94.71, 93.04, 93.08, 94.04, 92.08, 92.17, 88.72, 86.08, 89.26, 91.19, 90.56, 88.19, 89.54, 89.46, 89.6, 89.25, 92.16, 90.15, 89.09, 90.94, 94.92, 91.71, 91.89, 95.18, 95.46, 94.74, 94.92, 96.04, 95.67, 96.26, 96.16, 95.99, 96.03, 96.42, 96.57, 95.46, 96.18, 96.55, 95.85, 96.17, 96.02, 95.77, 95.92, 96.06, 95.45, 96.4, 96.57, 95.9, 94.39, 95.46, 95.35, 96.32, 93.59, 94.22, 93.79, 92.72, 92.19, 91.78, 90.54, 86.81, 86.29, 87.43, 85.01, 81.82, 80.47, 81.58, 72.73, 75.54, 80.21, 81.58, 81.47, 83.55, 85.15, 86.78, 85.54, 90.11, 92.48, 93.6, 93.92, 90.89, 91.75, 91.64, 89.87, 86.61, 87.21, 87.63, 84.68, 80.54, 81.36, 82.04, 74.21, 76.28, 67.76, 70.69, 68.4, 70.33, 67.13, 62.03, 66.09, 61.4, 54.92, 53.64, 49.81, 57.19, 44.65, 48.45, 49.3, 43.56]
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RING finger
Component of a SCF(SKP2)-like complex containing CUL1, SKP1, TRIM21 and SKP2.
SCF
null
IRF8, CALR, CUL1, FBXW11, HSPA5, IKBKB, IRF3, SKP1 , VCP,SKP2, DCP2 ,ULK1, BECN1,GABARAP, GABARAPL1, GABARAPL2 , MAP1LC3C,SQSTM1,IRF3 , NMI, IFI35 , CUL1, TRIM21
USP4, IKBKB, TRIM21, CDKN1B, IRF3, IRF8, MNI
mono, 63
null
UBE2D2, UBE2D1, UBE2E1, UBE2E2
Homotrimer
null
90.718042
0.406716
88.015919
0.456801
2,388
P19474
P37198
34257278
UbiBrowser
TRIM21
MASAARLTMMWEEVTCPICLDPFVEPVSIECGHSFCQECISQVGKGGGSVCPVCRQRFLLKNLRPNRQLANMVNNLKEISQEAREGTQGERCAVHGERLHLFCEKDGKALCWVCAQSRKHRDHAMVPLEEAAQEYQEKLQVALGELRRKQELAEKLEVEIAIKRADWKKTVETQKSRIHAEFVQQKNFLVEEEQRQLQELEKDEREQLRILGEKEAKLAQQSQALQELISELDRRCHSSALELLQEVIIVLERSESWNLKDLDITSPELRSVCHVPGLKKMLRTCAVHITLDPDTANPWLILSEDRRQVRLGDTQQSIPGNEERFDSYPMVLGAQHFHSGKHYWEVDVTGKEAWDLGVCRDSVRRKGHFLLSSKSGFWTIWLWNKQKYEAGTYPQTPLHLQVPPCQVGIFLDYEAGMVSFYNITDHGSLIYSFSECAFTGPLRPFFSPGFNDGGKNTAPLTLCPLNIGSQGSTDY
Homo sapiens
Cytoplasm, Cytoplasmic vesicle, autophagosome, Nucleus, Cytoplasm, P-body, Cytoplasm, Stress granule
Low tissue specificity
{'Ciliated cells': '3.8', 'Basal respiratory cells': '6.8', 'Club cells': '5.8', 'Ionocytes': '3.7', 'Mucus glandular cells': '4.8', 'Serous glandular cells': '2.3', 'Gastric mucus-secreting cells': '8.8', 'Proximal enterocytes': '8.9', 'Paneth cells': '3.9', 'Distal enterocytes': '8.5', 'Intestinal goblet cells': '8.4', 'Exocrine glandular cells': '-0.716', 'Basal prostatic cells': '5.4', 'Prostatic glandular cells': '5.0', 'Breast glandular cells': '0.298', 'Breast myoepithelial cells': '0.351', 'Glandular and luminal cells': '5.9', 'Secretory cells': '8.4', 'Basal keratinocytes': '3.2', 'Suprabasal keratinocytes': '2.7', 'Basal squamous epithelial cells': '6.4', 'Squamous epithelial cells': '4.3', 'Alveolar cells type 1': '0.116', 'Alveolar cells type 2': '0.115', 'Salivary duct cells': '3.0', 'Ductal cells': '0.700', 'Hepatocytes': '0.503', 'Cholangiocytes': '11.4', 'Proximal tubular cells': '0.175', 'Distal tubular cells': '0.0', 'Collecting duct cells': '5.8', 'Mesothelial cells': '0.451', 'Sertoli cells': '0.479', 'Granulosa cells': '4.8', 'Enteroendocrine cells': '3.7', 'Pancreatic endocrine cells': '3.4', 'Leydig cells': '0.632', 'Excitatory neurons': '0.2', 'Inhibitory neurons': '0.1', 'Cone photoreceptor cells': '0.0', 'Rod photoreceptor cells': '0.0', 'Bipolar cells': '0.7', 'Horizontal cells': '0.6', 'Astrocytes': '0.0', 'Oligodendrocyte precursor cells': '0.9', 'Oligodendrocytes': '0.1', 'Microglial cells': '1.8', 'Muller glia cells': '2.4', 'Schwann cells': '0.099', 'Spermatogonia': '0.401', 'Spermatocytes': '-0.062', 'Early spermatids': '-0.578', 'Late spermatids': '-0.618', 'Oocytes': '1.5', 'Cytotrophoblasts': '6.6', 'Syncytiotrophoblasts': '9.8', 'Extravillous trophoblasts': '10.0', 'Endothelial cells': '7.8', 'Lymphatic endothelial cells': '6.9', 'Cardiomyocytes': '0.335', 'Skeletal myocytes': '-0.080', 'Smooth muscle cells': '6.3', 'Adipocytes': '8.3', 'Melanocytes': '0.101', 'Fibroblasts': '6.5', 'Peritubular cells': '0.579', 'Endometrial stromal cells': '4.5', 'Ovarian stromal cells': '6.7', 'Undifferentiated cells': '5.9', 'T-cells': '9.9', 'B-cells': '8.8', 'Plasma cells': '5.0', 'Nk-cells': '15.1', 'Granulocytes': '6.2', 'Monocytes': '7.8', 'Macrophages': '8.5', 'Hofbauer cells': '9.9', 'Kupffer cells': '10.3', 'Dendritic cells': '8.0', 'Langerhans cells': '0.466', 'Erythroid cells': '-0.084', 'Adipocytes (Subcutaneous)': '-0.368', 'Adipocytes (Visceral)': '-0.167', 'Breast glandular cells (progenitors)': '0.190', 'Adipocytes (Breast)': '-0.382', 'Colon enterocytes': '0.004', 'Colon enteroendocrine cells': '0.196', 'Enteric glia cells': '-0.129', 'Mitotic cells (Colon)': '0.005', 'Mitotic cells (Heart)': '0.486', 'Podocytes': '-0.114', 'Ascending Loop of Henle cells': '0.371', 'Intercalated cells': '-0.097', 'Cholangiocyte': '0.375', 'NK-cells (Liver)': '-0.278', 'Respiratory ciliated cells': '-0.022', 'Mitotic cells (Lung)': '0.157', 'NK-cells (Lung)': '0.110', 'B-cells (Lung)': '-0.155', 'Alpha cells': '0.333', 'Beta cells': '0.161', 'Prostate glandular cells': '-0.162', 'Prostate basal glandular cells': '0.286', 'Urothelial cells': '0.283', 'Keratinocyte (other)': '0.121', 'Keratinocyte (granular)': '-0.008', 'Hair cortex cells': '-0.113', 'Inner root sheath cells': '-0.069', 'Outer root sheath cells': '0.125', 'Sebaceous gland cells': '0.110', 'Eccrine sweat gland cells': '0.070', 'Adipocytes (Skin)': '0.019', 'Mitotic cells (Skin)': '0.236', 'Parietal cells': '-0.609', 'Chief cells': '-0.599', 'Gastric mucous cells': '-0.193', 'Gastric enteroendocrine cells': '-0.441', 'Mitotic cells (Stomach)': '0.261', 'Parafollicular cells': '-0.028', 'Thyroid glandular cells': '0.094', 'Mitotic cells (Thyroid)': '0.242', 'Adrenal cortex cells': '0.619', 'Adrenal medulla cells': '0.063', 'Mitotic cells (Adrenal gland)': '0.483', 'Minor salivary glandular cells': '0.582', 'Minor salivary gland ductal cells': '0.072', 'Minor salivary gland basal cells': '0.229', 'Mitotic cells (Minor salivary gland)': '0.376', 'Adipocytes (Minor salivary gland)': '0.211', 'Somatotropes': '-0.121', 'Lactotropes': '-0.287', 'Gonadotropes': '0.004', 'Corticotropes': '-0.352', 'Thyrotropes': '-0.054', 'Undifferentiated cells (Pituitary gland)': '0.486', 'Mitotic cells (Spleen)': '-0.016', 'Platelets': '0.115', 'Erythrocytes': '0.098', 'Hematopoietic stem cells': '0.042', 'B-cells (Spleen)': '0.028', 'NK-cells (Spleen)': '0.157', 'Amygdala excitatory': '0.1', 'Cerebellar inhibitory': '0.2', 'Cge interneuron': '0.3', 'Deep-layer corticothalamic and 6b': '0.3', 'Deep-layer intratelencephalic': '0.1', 'Deep-layer near-projecting': '0.1', 'Eccentric medium spiny neuron': '0.4', 'Hippocampal ca1-3': '0.5', 'Hippocampal ca4': '0.1', 'Hippocampal dentate gyrus': '0.3', 'Lamp5-lhx6 and chandelier': '0.3', 'Lower rhombic lip': '0.2', 'Mammillary body': '0.4', 'Medium spiny neuron': '0.6', 'Mge interneuron': '0.1', 'Midbrain-derived inhibitory': '0.6', 'Miscellaneous': '0.6', 'Splatter': '0.5', 'Thalamic excitatory': '1.3', 'Upper rhombic lip': '0.1', 'Upper-layer intratelencephalic': '0.1', 'Astrocyte': '1.5', 'Bergmann glia': '1.5', 'Central nervous system macrophage': '6.0', 'Choroid plexus epithelial cell': '2.9', 'Committed oligodendrocyte precursor': '1.0', 'Ependymal cell': '1.3', 'Oligodendrocyte': '0.1', 'Oligodendrocyte precursor cell': '2.3', 'Endothelial cell': '6.4', 'Pericyte': '5.3', 'Vascular associated smooth muscle cell': '3.1', 'Fibroblast': '5.3', 'Leukocyte': '7.4', 'Basophil': '107.0', 'Eosinophil': '312.5', 'Neutrophil': '496.9', 'Classical monocyte': '25.8', 'Non-classical monocyte': '66.1', 'Intermediate monocyte': '117.0', 'T-reg': '72.1', 'GdT-cell': '89.5', 'MAIT T-cell': '61.2', 'Memory CD4 T-cell': '76.8', 'Naive CD4 T-cell': '47.0', 'Memory CD8 T-cell': '81.1', 'Naive CD8 T-cell': '43.5', 'Memory B-cell': '50.4', 'Naive B-cell': '38.5', 'Plasmacytoid DC': '47.5', 'Myeloid DC': '92.2', 'NK-cell': '88.9', 'Total PBMC': '83.8', 'Vd2 gdTCR': '67.8', 'Memory CD4 T-cell Th1\\/Th17': '48.0', 'Memory CD4 T-cell Th17': '54.6', 'Memory CD4 T-cell Th2': '54.8', 'Non-Vd2 gdTCR': '73.7', 'Memory CD4 T-cell Th1': '58.8', 'Memory CD4 T-cell TFH': '61.9', 'Terminal effector memory CD4 T-cell': '72.8', 'Central memory CD8 T-cell': '59.9', 'Effector memory CD8 T-cell': '90.7', 'Terminal effector memory CD8 T-cell': '75.8', 'Non-switched memory B-cell': '52.6', 'Plasmablast': '62.3', 'Switched memory B-cell': '55.8', 'Exhausted memory B-cell': '52.1', 'Progenitor cell': '44.7', 'Memory T-reg': '82.4', 'Naive CD4 T-cell activated': '133.9', 'Naive CD8 T-cell activated': '163.4', 'Naive T-reg': '54.7'}
2IWG, 5JPX, 5OLM, 6FGA, 6S53, 7BBD, 8A58
{'Adipose Tissue': 21.42795099667774, 'Adrenal Gland': 16.707763565891472, 'Bladder': 21.861904761904764, 'Blood': 61.11958557588805, 'Blood Vessel': 22.62928389513109, 'Brain': 4.305000416351249, 'Breast': 20.001740740740743, 'Cervix Uteri': 26.420526315789473, 'Colon': 23.40817458279846, 'Esophagus': 21.74157577854671, 'Fallopian Tube': 25.39, 'Heart': 6.66628106852497, 'Kidney': 13.61479775280899, 'Liver': 10.388, 'Lung': 32.00464878892734, 'Muscle': 3.944284806973848, 'Nerve': 25.39305008077545, 'Ovary': 30.51811111111111, 'Pancreas': 6.808080182926829, 'Pituitary': 12.995699646643107, 'Prostate': 21.00597551020408, 'Salivary Gland': 16.434148148148147, 'Skin': 17.851811498065228, 'Small Intestine': 28.907085561497325, 'Spleen': 50.16024896265561, 'Stomach': 19.072721448467966, 'Testis': 6.377013850415512, 'Thyroid': 21.553307810107196, 'Uterus': 29.83549295774648, 'Vagina': 21.551141025641027}
NUP62
MSGFNFGGTGAPTGGFTFGTAKTATTTPATGFSFSTSGTGGFNFGAPFQPATSTPSTGLFSLATQTPATQTTGFTFGTATLASGGTGFSLGIGASKLNLSNTAATPAMANPSGFGLGSSNLTNAISSTVTSSQGTAPTGFVFGPSTTSVAPATTSGGFSFTGGSTAQPSGFNIGSAGNSAQPTAPATLPFTPATPAATTAGATQPAAPTPTATITSTGPSLFASIATAPTSSATTGLSLCTPVTTAGAPTAGTQGFSLKAPGAASGTSTTTSTAATATATTTSSSSTTGFALNLKPLAPAGIPSNTAAAVTAPPGPGAAAGAAASSAMTYAQLESLINKWSLELEDQERHFLQQATQVNAWDRTLIENGEKITSLHREVEKVKLDQKRLDQELDFILSQQKELEDLLSPLEELVKEQSGTIYLQHADEEREKTYKLAENIDAQLKRMAQDLKDIIEHLNTSGAPADTSDPLQQICKILNAHMDSLQWIDQNSALLQRKVEEVTKVCEGRRKEQERSFRITFD
Homo sapiens
Nucleus, nuclear pore complex, Cytoplasm, cytoskeleton, spindle pole, Nucleus envelope, Cytoplasm, cytoskeleton, microtubule organizing center, centrosome
Low tissue specificity
{'Ciliated cells': '15.8', 'Basal respiratory cells': '15.2', 'Club cells': '20.1', 'Ionocytes': '12.5', 'Mucus glandular cells': '19.0', 'Serous glandular cells': '11.9', 'Gastric mucus-secreting cells': '19.5', 'Proximal enterocytes': '18.9', 'Paneth cells': '24.3', 'Distal enterocytes': '21.5', 'Intestinal goblet cells': '22.2', 'Exocrine glandular cells': '-0.772', 'Basal prostatic cells': '19.0', 'Prostatic glandular cells': '19.8', 'Breast glandular cells': '0.526', 'Breast myoepithelial cells': '0.468', 'Glandular and luminal cells': '24.8', 'Secretory cells': '30.0', 'Basal keratinocytes': '32.3', 'Suprabasal keratinocytes': '27.8', 'Basal squamous epithelial cells': '21.5', 'Squamous epithelial cells': '18.9', 'Alveolar cells type 1': '-0.122', 'Alveolar cells type 2': '0.047', 'Salivary duct cells': '17.4', 'Ductal cells': '0.664', 'Hepatocytes': '0.234', 'Cholangiocytes': '21.0', 'Proximal tubular cells': '0.258', 'Distal tubular cells': '0.0', 'Collecting duct cells': '9.7', 'Mesothelial cells': '0.407', 'Sertoli cells': '-0.452', 'Granulosa cells': '20.8', 'Enteroendocrine cells': '19.9', 'Pancreatic endocrine cells': '17.0', 'Leydig cells': '-0.497', 'Excitatory neurons': '0.0', 'Inhibitory neurons': '0.0', 'Cone photoreceptor cells': '17.0', 'Rod photoreceptor cells': '13.9', 'Bipolar cells': '13.0', 'Horizontal cells': '18.3', 'Astrocytes': '0.0', 'Oligodendrocyte precursor cells': '0.0', 'Oligodendrocytes': '0.0', 'Microglial cells': '0.0', 'Muller glia cells': '19.0', 'Schwann cells': '-0.080', 'Spermatogonia': '-0.108', 'Spermatocytes': '0.250', 'Early spermatids': '0.660', 'Late spermatids': '0.636', 'Oocytes': '54.4', 'Cytotrophoblasts': '39.9', 'Syncytiotrophoblasts': '22.1', 'Extravillous trophoblasts': '46.2', 'Endothelial cells': '23.3', 'Lymphatic endothelial cells': '14.7', 'Cardiomyocytes': '0.606', 'Skeletal myocytes': '-0.214', 'Smooth muscle cells': '16.7', 'Adipocytes': '15.9', 'Melanocytes': '0.288', 'Fibroblasts': '18.1', 'Peritubular cells': '-0.350', 'Endometrial stromal cells': '23.0', 'Ovarian stromal cells': '20.3', 'Undifferentiated cells': '35.1', 'T-cells': '23.4', 'B-cells': '28.9', 'Plasma cells': '28.3', 'Nk-cells': '20.1', 'Granulocytes': '26.9', 'Monocytes': '18.2', 'Macrophages': '45.9', 'Hofbauer cells': '52.1', 'Kupffer cells': '38.8', 'Dendritic cells': '52.8', 'Langerhans cells': '0.422', 'Erythroid cells': '0.071', 'Adipocytes (Subcutaneous)': '-0.288', 'Adipocytes (Visceral)': '-0.273', 'Breast glandular cells (progenitors)': '0.489', 'Adipocytes (Breast)': '-0.447', 'Colon enterocytes': '-0.111', 'Colon enteroendocrine cells': '0.250', 'Enteric glia cells': '0.000', 'Mitotic cells (Colon)': '-0.126', 'Mitotic cells (Heart)': '0.536', 'Podocytes': '-0.152', 'Ascending Loop of Henle cells': '0.357', 'Intercalated cells': '-0.158', 'Cholangiocyte': '0.215', 'NK-cells (Liver)': '-0.259', 'Respiratory ciliated cells': '-0.043', 'Mitotic cells (Lung)': '0.274', 'NK-cells (Lung)': '-0.012', 'B-cells (Lung)': '-0.098', 'Alpha cells': '0.432', 'Beta cells': '0.264', 'Prostate glandular cells': '-0.009', 'Prostate basal glandular cells': '0.363', 'Urothelial cells': '0.399', 'Keratinocyte (other)': '0.365', 'Keratinocyte (granular)': '0.082', 'Hair cortex cells': '-0.054', 'Inner root sheath cells': '-0.017', 'Outer root sheath cells': '0.074', 'Sebaceous gland cells': '0.114', 'Eccrine sweat gland cells': '-0.158', 'Adipocytes (Skin)': '-0.130', 'Mitotic cells (Skin)': '0.348', 'Parietal cells': '-0.620', 'Chief cells': '-0.522', 'Gastric mucous cells': '-0.243', 'Gastric enteroendocrine cells': '-0.340', 'Mitotic cells (Stomach)': '0.242', 'Parafollicular cells': '0.051', 'Thyroid glandular cells': '0.264', 'Mitotic cells (Thyroid)': '0.151', 'Adrenal cortex cells': '0.433', 'Adrenal medulla cells': '-0.112', 'Mitotic cells (Adrenal gland)': '0.235', 'Minor salivary glandular cells': '0.550', 'Minor salivary gland ductal cells': '0.035', 'Minor salivary gland basal cells': '0.297', 'Mitotic cells (Minor salivary gland)': '0.426', 'Adipocytes (Minor salivary gland)': '0.119', 'Somatotropes': '0.236', 'Lactotropes': '0.261', 'Gonadotropes': '0.141', 'Corticotropes': '0.077', 'Thyrotropes': '0.209', 'Undifferentiated cells (Pituitary gland)': '0.095', 'Mitotic cells (Spleen)': '0.074', 'Platelets': '-0.085', 'Erythrocytes': '-0.106', 'Hematopoietic stem cells': '-0.216', 'B-cells (Spleen)': '0.353', 'NK-cells (Spleen)': '0.152', 'Amygdala excitatory': '0.0', 'Cerebellar inhibitory': '0.1', 'Cge interneuron': '0.1', 'Deep-layer corticothalamic and 6b': '0.0', 'Deep-layer intratelencephalic': '0.0', 'Deep-layer near-projecting': '0.0', 'Eccentric medium spiny neuron': '0.0', 'Hippocampal ca1-3': '0.0', 'Hippocampal ca4': '0.0', 'Hippocampal dentate gyrus': '0.1', 'Lamp5-lhx6 and chandelier': '0.0', 'Lower rhombic lip': '0.0', 'Mammillary body': '0.1', 'Medium spiny neuron': '0.0', 'Mge interneuron': '0.0', 'Midbrain-derived inhibitory': '0.0', 'Miscellaneous': '0.0', 'Splatter': '0.1', 'Thalamic excitatory': '0.0', 'Upper rhombic lip': '0.1', 'Upper-layer intratelencephalic': '0.2', 'Astrocyte': '0.1', 'Bergmann glia': '0.0', 'Central nervous system macrophage': '0.1', 'Choroid plexus epithelial cell': '0.0', 'Committed oligodendrocyte precursor': '0.0', 'Ependymal cell': '0.1', 'Oligodendrocyte': '0.1', 'Oligodendrocyte precursor cell': '0.1', 'Endothelial cell': '0.3', 'Pericyte': '0.1', 'Vascular associated smooth muscle cell': '0.0', 'Fibroblast': '0.2', 'Leukocyte': '0.0', 'Basophil': '31.7', 'Eosinophil': '7.2', 'Neutrophil': '20.8', 'Classical monocyte': '29.7', 'Non-classical monocyte': '20.6', 'Intermediate monocyte': '106.5', 'T-reg': '50.9', 'GdT-cell': '17.9', 'MAIT T-cell': '85.8', 'Memory CD4 T-cell': '17.9', 'Naive CD4 T-cell': '16.0', 'Memory CD8 T-cell': '20.0', 'Naive CD8 T-cell': '16.7', 'Memory B-cell': '15.5', 'Naive B-cell': '11.5', 'Plasmacytoid DC': '128.9', 'Myeloid DC': '124.0', 'NK-cell': '23.5', 'Total PBMC': '67.9', 'Vd2 gdTCR': '67.7', 'Memory CD4 T-cell Th1\\/Th17': '21.4', 'Memory CD4 T-cell Th17': '26.7', 'Memory CD4 T-cell Th2': '22.3', 'Non-Vd2 gdTCR': '60.7', 'Memory CD4 T-cell Th1': '22.9', 'Memory CD4 T-cell TFH': '30.2', 'Terminal effector memory CD4 T-cell': '69.5', 'Central memory CD8 T-cell': '60.7', 'Effector memory CD8 T-cell': '67.3', 'Terminal effector memory CD8 T-cell': '62.6', 'Non-switched memory B-cell': '64.4', 'Plasmablast': '89.6', 'Switched memory B-cell': '80.8', 'Exhausted memory B-cell': '63.8', 'Progenitor cell': '54.5', 'Memory T-reg': '29.5', 'Naive CD4 T-cell activated': '74.7', 'Naive CD8 T-cell activated': '89.4', 'Naive T-reg': '23.7'}
5IJN, 5IJO, 7PER, 7R5J, 7R5K
{'Adipose Tissue': 22.10853239202658, 'Adrenal Gland': 26.5286976744186, 'Bladder': 27.488095238095237, 'Blood': 27.6130272335845, 'Blood Vessel': 25.24059475655431, 'Brain': 13.841426192278576, 'Breast': 23.08595424836601, 'Cervix Uteri': 32.630526315789474, 'Colon': 23.92154813863928, 'Esophagus': 23.618880968858132, 'Fallopian Tube': 31.54444444444444, 'Heart': 8.914619860627177, 'Kidney': 13.908550561797751, 'Liver': 14.359814159292036, 'Lung': 25.323754325259515, 'Muscle': 16.847869240348693, 'Nerve': 25.17880452342488, 'Ovary': 28.559111111111115, 'Pancreas': 9.506932926829268, 'Pituitary': 29.691134275618374, 'Prostate': 26.15110204081633, 'Salivary Gland': 21.94283950617284, 'Skin': 28.99767274737424, 'Small Intestine': 26.561657754010692, 'Spleen': 32.700995850622405, 'Stomach': 17.073927576601672, 'Testis': 62.511108033240994, 'Thyroid': 23.997920367534455, 'Uterus': 36.38183098591549, 'Vagina': 26.07371794871795}
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[1.0, 0.92, 1.0, 0.89, 0.98, 0.93, 0.94, 0.99, 0.98, 0.96, 0.93, 0.97, 0.96, 0.97, 1.0, 1.0, 1.0, 1.0, 0.98, 1.0, 0.97, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 0.91, 0.96, 0.92, 0.97, 0.95, 1.0, 0.94, 1.0, 0.87, 1.0, 0.96, 0.96, 0.97, 0.87, 0.91, 0.98, 0.97, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 0.98, 0.91, 0.95, 0.83, 0.99, 0.99, 0.98, 1.0, 0.9, 1.0, 0.91, 0.98, 1.0, 0.99, 0.98, 0.99, 0.92, 0.98, 1.0, 0.99, 1.0, 0.97, 1.0, 1.0, 0.99, 1.0, 0.99, 1.0, 0.96, 0.99, 0.86, 0.99, 0.96, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 0.99, 1.0, 1.0, 0.99, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 0.98, 1.0, 0.96, 1.0, 0.91, 1.0, 0.9, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 0.92, 0.81, 0.57, 0.29, 0.73, 0.84, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 0.99, 0.98, 0.98, 0.98, 1.0, 0.99, 0.98, 1.0, 0.97, 0.96, 1.0, 0.95, 1.0, 1.0, 1.0, 1.0, 1.0, 0.93, 1.0, 0.93, 1.0, 1.0, 1.0, 1.0, 0.97, 1.0, 0.96, 0.98, 0.93, 0.84, 0.98, 0.77, 0.95, 0.97, 1.0, 0.97, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 0.99, 1.0, 0.98, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 0.97, 0.96, 0.97, 0.99, 1.0, 1.0, 1.0, 0.97, 0.85, 0.75, 0.89, 0.55, 0.77, 0.92, 0.7, 0.94, 0.91, 0.87, 0.88, 0.91, 0.9, 1.0, 0.99, 1.0, 0.94, 1.0, 0.85, 0.57, 0.1, 0.2, 0.78, 0.97, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 0.99, 0.96, 0.97, 0.96, 0.8, 0.9, 0.89, 0.87, 0.89, 0.92, 0.96, 0.81, 1.0, 0.94, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 0.98, 1.0, 0.99, 1.0, 1.0, 0.99, 1.0, 1.0, 1.0, 1.0, 0.98, 0.92, 0.87, 0.87, 0.82, 0.8, 0.72, 0.83, 0.69, 0.8, 0.79, 0.83, 0.89, 0.93, 0.94, 0.96, 0.97, 0.97, 1.0, 0.99, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 0.99, 0.98, 1.0, 0.94, 1.0, 0.93, 1.0, 0.94, 0.91, 0.86, 0.82, 0.8, 0.84, 0.8, 0.43, 0.66, 0.78, 0.64, 0.51, 0.44, 0.54, 0.58, 0.31, 0.47, 0.53, 0.52, 0.6, 0.55, 0.64, 0.43, 0.68, 0.44, 0.49, 0.64, 0.57, 0.56, 0.41, 0.68, 0.58, 0.56, 0.57, 0.34, 0.65, 0.49, 0.53, 0.51, 0.47, 0.42, 0.49, 0.64, 0.47, 0.69, 0.53, 0.51, 0.41, 0.37, 0.64, 0.51, 0.65, 0.46, 0.53, 0.63, 0.61, 0.65, 0.5, 0.46, 0.41, 0.48, 0.55, 0.46, 0.65, 0.48, 0.53, 0.58, 0.64, 0.55, 0.41, 0.65, 0.41, 0.54, 0.62, 0.55, 0.45, 0.56, 0.46, 0.49, 0.36, 0.43, 0.67, 0.51, 0.41, 0.56, 0.62, 0.32, 0.51, 0.47, 0.5, 0.58, 0.67, 0.51, 0.57, 0.77, 0.63, 0.55, 0.68, 0.81, 0.82, 0.58, 0.94, 0.53, 0.7, 0.73, 0.7, 0.23, 0.36, 0.7, 0.53, 0.46, 0.56, 0.62, 0.64, 0.49, 0.56, 0.47, 0.53, 0.49, 0.48, 0.42, 0.39, 0.47, 0.55, 0.6, 0.69, 0.54, 0.53, 0.47, 0.52, 0.58, 0.58, 0.39, 0.49, 0.57, 0.59, 0.64, 0.57, 0.45, 0.59, 0.77, 0.2, 0.41, 0.54, 0.88, 0.6, 0.52, 0.8, 0.39, 0.59, 0.63, 0.12, 0.58, 0.52, 0.34, 0.2, 0.44, 0.61, 0.44, 0.54, 0.55, 0.57, 0.61, 0.44, 0.56, 0.46, 0.68, 0.54, 0.68, 0.63, 0.37, 0.5, 0.5, 0.54, 0.64, 0.59, 0.72, 0.51, 0.55, 0.41, 0.47, 0.59, 0.49, 0.63, 0.55, 0.51, 0.39, 0.37, 0.63, 0.44, 0.19, 0.44, 0.64, 0.37, 0.37, 0.5, 0.59, 0.71, 0.76, 0.77, 0.73, 0.85]
RING finger
Component of a SCF(SKP2)-like complex containing CUL1, SKP1, TRIM21 and SKP2.
SCF
null
IRF8, CALR, CUL1, FBXW11, HSPA5, IKBKB, IRF3, SKP1 , VCP,SKP2, DCP2 ,ULK1, BECN1,GABARAP, GABARAPL1, GABARAPL2 , MAP1LC3C,SQSTM1,IRF3 , NMI, IFI35 , CUL1, TRIM21
USP4, IKBKB, TRIM21, CDKN1B, IRF3, IRF8, MNI
mono, 63
null
UBE2D2, UBE2D1, UBE2E1, UBE2E2
Homotrimer
null
90.718042
0.406716
57.621475
0.799023
1,492
P19474
P38936
33900537
UbiBrowser
TRIM21
MASAARLTMMWEEVTCPICLDPFVEPVSIECGHSFCQECISQVGKGGGSVCPVCRQRFLLKNLRPNRQLANMVNNLKEISQEAREGTQGERCAVHGERLHLFCEKDGKALCWVCAQSRKHRDHAMVPLEEAAQEYQEKLQVALGELRRKQELAEKLEVEIAIKRADWKKTVETQKSRIHAEFVQQKNFLVEEEQRQLQELEKDEREQLRILGEKEAKLAQQSQALQELISELDRRCHSSALELLQEVIIVLERSESWNLKDLDITSPELRSVCHVPGLKKMLRTCAVHITLDPDTANPWLILSEDRRQVRLGDTQQSIPGNEERFDSYPMVLGAQHFHSGKHYWEVDVTGKEAWDLGVCRDSVRRKGHFLLSSKSGFWTIWLWNKQKYEAGTYPQTPLHLQVPPCQVGIFLDYEAGMVSFYNITDHGSLIYSFSECAFTGPLRPFFSPGFNDGGKNTAPLTLCPLNIGSQGSTDY
Homo sapiens
Cytoplasm, Cytoplasmic vesicle, autophagosome, Nucleus, Cytoplasm, P-body, Cytoplasm, Stress granule
Low tissue specificity
{'Ciliated cells': '3.8', 'Basal respiratory cells': '6.8', 'Club cells': '5.8', 'Ionocytes': '3.7', 'Mucus glandular cells': '4.8', 'Serous glandular cells': '2.3', 'Gastric mucus-secreting cells': '8.8', 'Proximal enterocytes': '8.9', 'Paneth cells': '3.9', 'Distal enterocytes': '8.5', 'Intestinal goblet cells': '8.4', 'Exocrine glandular cells': '-0.716', 'Basal prostatic cells': '5.4', 'Prostatic glandular cells': '5.0', 'Breast glandular cells': '0.298', 'Breast myoepithelial cells': '0.351', 'Glandular and luminal cells': '5.9', 'Secretory cells': '8.4', 'Basal keratinocytes': '3.2', 'Suprabasal keratinocytes': '2.7', 'Basal squamous epithelial cells': '6.4', 'Squamous epithelial cells': '4.3', 'Alveolar cells type 1': '0.116', 'Alveolar cells type 2': '0.115', 'Salivary duct cells': '3.0', 'Ductal cells': '0.700', 'Hepatocytes': '0.503', 'Cholangiocytes': '11.4', 'Proximal tubular cells': '0.175', 'Distal tubular cells': '0.0', 'Collecting duct cells': '5.8', 'Mesothelial cells': '0.451', 'Sertoli cells': '0.479', 'Granulosa cells': '4.8', 'Enteroendocrine cells': '3.7', 'Pancreatic endocrine cells': '3.4', 'Leydig cells': '0.632', 'Excitatory neurons': '0.2', 'Inhibitory neurons': '0.1', 'Cone photoreceptor cells': '0.0', 'Rod photoreceptor cells': '0.0', 'Bipolar cells': '0.7', 'Horizontal cells': '0.6', 'Astrocytes': '0.0', 'Oligodendrocyte precursor cells': '0.9', 'Oligodendrocytes': '0.1', 'Microglial cells': '1.8', 'Muller glia cells': '2.4', 'Schwann cells': '0.099', 'Spermatogonia': '0.401', 'Spermatocytes': '-0.062', 'Early spermatids': '-0.578', 'Late spermatids': '-0.618', 'Oocytes': '1.5', 'Cytotrophoblasts': '6.6', 'Syncytiotrophoblasts': '9.8', 'Extravillous trophoblasts': '10.0', 'Endothelial cells': '7.8', 'Lymphatic endothelial cells': '6.9', 'Cardiomyocytes': '0.335', 'Skeletal myocytes': '-0.080', 'Smooth muscle cells': '6.3', 'Adipocytes': '8.3', 'Melanocytes': '0.101', 'Fibroblasts': '6.5', 'Peritubular cells': '0.579', 'Endometrial stromal cells': '4.5', 'Ovarian stromal cells': '6.7', 'Undifferentiated cells': '5.9', 'T-cells': '9.9', 'B-cells': '8.8', 'Plasma cells': '5.0', 'Nk-cells': '15.1', 'Granulocytes': '6.2', 'Monocytes': '7.8', 'Macrophages': '8.5', 'Hofbauer cells': '9.9', 'Kupffer cells': '10.3', 'Dendritic cells': '8.0', 'Langerhans cells': '0.466', 'Erythroid cells': '-0.084', 'Adipocytes (Subcutaneous)': '-0.368', 'Adipocytes (Visceral)': '-0.167', 'Breast glandular cells (progenitors)': '0.190', 'Adipocytes (Breast)': '-0.382', 'Colon enterocytes': '0.004', 'Colon enteroendocrine cells': '0.196', 'Enteric glia cells': '-0.129', 'Mitotic cells (Colon)': '0.005', 'Mitotic cells (Heart)': '0.486', 'Podocytes': '-0.114', 'Ascending Loop of Henle cells': '0.371', 'Intercalated cells': '-0.097', 'Cholangiocyte': '0.375', 'NK-cells (Liver)': '-0.278', 'Respiratory ciliated cells': '-0.022', 'Mitotic cells (Lung)': '0.157', 'NK-cells (Lung)': '0.110', 'B-cells (Lung)': '-0.155', 'Alpha cells': '0.333', 'Beta cells': '0.161', 'Prostate glandular cells': '-0.162', 'Prostate basal glandular cells': '0.286', 'Urothelial cells': '0.283', 'Keratinocyte (other)': '0.121', 'Keratinocyte (granular)': '-0.008', 'Hair cortex cells': '-0.113', 'Inner root sheath cells': '-0.069', 'Outer root sheath cells': '0.125', 'Sebaceous gland cells': '0.110', 'Eccrine sweat gland cells': '0.070', 'Adipocytes (Skin)': '0.019', 'Mitotic cells (Skin)': '0.236', 'Parietal cells': '-0.609', 'Chief cells': '-0.599', 'Gastric mucous cells': '-0.193', 'Gastric enteroendocrine cells': '-0.441', 'Mitotic cells (Stomach)': '0.261', 'Parafollicular cells': '-0.028', 'Thyroid glandular cells': '0.094', 'Mitotic cells (Thyroid)': '0.242', 'Adrenal cortex cells': '0.619', 'Adrenal medulla cells': '0.063', 'Mitotic cells (Adrenal gland)': '0.483', 'Minor salivary glandular cells': '0.582', 'Minor salivary gland ductal cells': '0.072', 'Minor salivary gland basal cells': '0.229', 'Mitotic cells (Minor salivary gland)': '0.376', 'Adipocytes (Minor salivary gland)': '0.211', 'Somatotropes': '-0.121', 'Lactotropes': '-0.287', 'Gonadotropes': '0.004', 'Corticotropes': '-0.352', 'Thyrotropes': '-0.054', 'Undifferentiated cells (Pituitary gland)': '0.486', 'Mitotic cells (Spleen)': '-0.016', 'Platelets': '0.115', 'Erythrocytes': '0.098', 'Hematopoietic stem cells': '0.042', 'B-cells (Spleen)': '0.028', 'NK-cells (Spleen)': '0.157', 'Amygdala excitatory': '0.1', 'Cerebellar inhibitory': '0.2', 'Cge interneuron': '0.3', 'Deep-layer corticothalamic and 6b': '0.3', 'Deep-layer intratelencephalic': '0.1', 'Deep-layer near-projecting': '0.1', 'Eccentric medium spiny neuron': '0.4', 'Hippocampal ca1-3': '0.5', 'Hippocampal ca4': '0.1', 'Hippocampal dentate gyrus': '0.3', 'Lamp5-lhx6 and chandelier': '0.3', 'Lower rhombic lip': '0.2', 'Mammillary body': '0.4', 'Medium spiny neuron': '0.6', 'Mge interneuron': '0.1', 'Midbrain-derived inhibitory': '0.6', 'Miscellaneous': '0.6', 'Splatter': '0.5', 'Thalamic excitatory': '1.3', 'Upper rhombic lip': '0.1', 'Upper-layer intratelencephalic': '0.1', 'Astrocyte': '1.5', 'Bergmann glia': '1.5', 'Central nervous system macrophage': '6.0', 'Choroid plexus epithelial cell': '2.9', 'Committed oligodendrocyte precursor': '1.0', 'Ependymal cell': '1.3', 'Oligodendrocyte': '0.1', 'Oligodendrocyte precursor cell': '2.3', 'Endothelial cell': '6.4', 'Pericyte': '5.3', 'Vascular associated smooth muscle cell': '3.1', 'Fibroblast': '5.3', 'Leukocyte': '7.4', 'Basophil': '107.0', 'Eosinophil': '312.5', 'Neutrophil': '496.9', 'Classical monocyte': '25.8', 'Non-classical monocyte': '66.1', 'Intermediate monocyte': '117.0', 'T-reg': '72.1', 'GdT-cell': '89.5', 'MAIT T-cell': '61.2', 'Memory CD4 T-cell': '76.8', 'Naive CD4 T-cell': '47.0', 'Memory CD8 T-cell': '81.1', 'Naive CD8 T-cell': '43.5', 'Memory B-cell': '50.4', 'Naive B-cell': '38.5', 'Plasmacytoid DC': '47.5', 'Myeloid DC': '92.2', 'NK-cell': '88.9', 'Total PBMC': '83.8', 'Vd2 gdTCR': '67.8', 'Memory CD4 T-cell Th1\\/Th17': '48.0', 'Memory CD4 T-cell Th17': '54.6', 'Memory CD4 T-cell Th2': '54.8', 'Non-Vd2 gdTCR': '73.7', 'Memory CD4 T-cell Th1': '58.8', 'Memory CD4 T-cell TFH': '61.9', 'Terminal effector memory CD4 T-cell': '72.8', 'Central memory CD8 T-cell': '59.9', 'Effector memory CD8 T-cell': '90.7', 'Terminal effector memory CD8 T-cell': '75.8', 'Non-switched memory B-cell': '52.6', 'Plasmablast': '62.3', 'Switched memory B-cell': '55.8', 'Exhausted memory B-cell': '52.1', 'Progenitor cell': '44.7', 'Memory T-reg': '82.4', 'Naive CD4 T-cell activated': '133.9', 'Naive CD8 T-cell activated': '163.4', 'Naive T-reg': '54.7'}
2IWG, 5JPX, 5OLM, 6FGA, 6S53, 7BBD, 8A58
{'Adipose Tissue': 21.42795099667774, 'Adrenal Gland': 16.707763565891472, 'Bladder': 21.861904761904764, 'Blood': 61.11958557588805, 'Blood Vessel': 22.62928389513109, 'Brain': 4.305000416351249, 'Breast': 20.001740740740743, 'Cervix Uteri': 26.420526315789473, 'Colon': 23.40817458279846, 'Esophagus': 21.74157577854671, 'Fallopian Tube': 25.39, 'Heart': 6.66628106852497, 'Kidney': 13.61479775280899, 'Liver': 10.388, 'Lung': 32.00464878892734, 'Muscle': 3.944284806973848, 'Nerve': 25.39305008077545, 'Ovary': 30.51811111111111, 'Pancreas': 6.808080182926829, 'Pituitary': 12.995699646643107, 'Prostate': 21.00597551020408, 'Salivary Gland': 16.434148148148147, 'Skin': 17.851811498065228, 'Small Intestine': 28.907085561497325, 'Spleen': 50.16024896265561, 'Stomach': 19.072721448467966, 'Testis': 6.377013850415512, 'Thyroid': 21.553307810107196, 'Uterus': 29.83549295774648, 'Vagina': 21.551141025641027}
CDKN1A
MSEPAGDVRQNPCGSKACRRLFGPVDSEQLSRDCDALMAGCIQEARERWNFDFVTETPLEGDFAWERVRGLGLPKLYLPTGPRRGRDELGGGRRPGTSPALLQGTAEEDHVDLSLSCTLVPRSGEQAEGSPGGPGDSQGRKRRQTSMTDFYHSKRRLIFSKRKP
Homo sapiens
Cytoplasm, Nucleus
Low tissue specificity
{'Ciliated cells': '219.2', 'Basal respiratory cells': '269.5', 'Club cells': '189.1', 'Ionocytes': '279.8', 'Mucus glandular cells': '202.6', 'Serous glandular cells': '151.8', 'Gastric mucus-secreting cells': '136.2', 'Proximal enterocytes': '345.5', 'Paneth cells': '170.9', 'Distal enterocytes': '374.3', 'Intestinal goblet cells': '199.6', 'Exocrine glandular cells': '-0.503', 'Basal prostatic cells': '263.3', 'Prostatic glandular cells': '36.9', 'Breast glandular cells': '-0.093', 'Breast myoepithelial cells': '0.013', 'Glandular and luminal cells': '205.8', 'Secretory cells': '211.3', 'Basal keratinocytes': '338.3', 'Suprabasal keratinocytes': '625.4', 'Basal squamous epithelial cells': '564.7', 'Squamous epithelial cells': '599.4', 'Alveolar cells type 1': '-0.006', 'Alveolar cells type 2': '-0.268', 'Salivary duct cells': '211.4', 'Ductal cells': '0.254', 'Hepatocytes': '-0.189', 'Cholangiocytes': '24.8', 'Proximal tubular cells': '0.179', 'Distal tubular cells': '43.0', 'Collecting duct cells': '77.8', 'Mesothelial cells': '-0.166', 'Sertoli cells': '0.547', 'Granulosa cells': '96.6', 'Enteroendocrine cells': '226.3', 'Pancreatic endocrine cells': '156.2', 'Leydig cells': '0.537', 'Excitatory neurons': '0.4', 'Inhibitory neurons': '0.4', 'Cone photoreceptor cells': '0.0', 'Rod photoreceptor cells': '0.8', 'Bipolar cells': '1.2', 'Horizontal cells': '1.3', 'Astrocytes': '0.9', 'Oligodendrocyte precursor cells': '0.0', 'Oligodendrocytes': '0.4', 'Microglial cells': '5.4', 'Muller glia cells': '67.7', 'Schwann cells': '-0.047', 'Spermatogonia': '0.312', 'Spermatocytes': '-0.173', 'Early spermatids': '-0.577', 'Late spermatids': '-0.573', 'Oocytes': '17.6', 'Cytotrophoblasts': '40.0', 'Syncytiotrophoblasts': '172.4', 'Extravillous trophoblasts': '57.7', 'Endothelial cells': '417.4', 'Lymphatic endothelial cells': '198.2', 'Cardiomyocytes': '0.152', 'Skeletal myocytes': '-0.199', 'Smooth muscle cells': '464.8', 'Adipocytes': '577.5', 'Melanocytes': '0.167', 'Fibroblasts': '258.4', 'Peritubular cells': '0.389', 'Endometrial stromal cells': '54.7', 'Ovarian stromal cells': '204.0', 'Undifferentiated cells': '43.2', 'T-cells': '98.5', 'B-cells': '134.5', 'Plasma cells': '326.2', 'Nk-cells': '26.2', 'Granulocytes': '246.5', 'Monocytes': '506.5', 'Macrophages': '288.1', 'Hofbauer cells': '139.3', 'Kupffer cells': '74.3', 'Dendritic cells': '95.0', 'Langerhans cells': '-0.032', 'Erythroid cells': '0.037', 'Adipocytes (Subcutaneous)': '-0.360', 'Adipocytes (Visceral)': '0.069', 'Breast glandular cells (progenitors)': '-0.168', 'Adipocytes (Breast)': '-0.071', 'Colon enterocytes': '-0.005', 'Colon enteroendocrine cells': '-0.041', 'Enteric glia cells': '-0.179', 'Mitotic cells (Colon)': '0.208', 'Mitotic cells (Heart)': '0.293', 'Podocytes': '0.152', 'Ascending Loop of Henle cells': '-0.065', 'Intercalated cells': '-0.145', 'Cholangiocyte': '0.343', 'NK-cells (Liver)': '-0.217', 'Respiratory ciliated cells': '-0.033', 'Mitotic cells (Lung)': '-0.190', 'NK-cells (Lung)': '0.157', 'B-cells (Lung)': '0.184', 'Alpha cells': '0.226', 'Beta cells': '0.160', 'Prostate glandular cells': '-0.244', 'Prostate basal glandular cells': '-0.132', 'Urothelial cells': '0.171', 'Keratinocyte (other)': '0.183', 'Keratinocyte (granular)': '-0.193', 'Hair cortex cells': '0.051', 'Inner root sheath cells': '0.111', 'Outer root sheath cells': '0.189', 'Sebaceous gland cells': '-0.160', 'Eccrine sweat gland cells': '-0.080', 'Adipocytes (Skin)': '-0.298', 'Mitotic cells (Skin)': '0.119', 'Parietal cells': '-0.445', 'Chief cells': '-0.447', 'Gastric mucous cells': '-0.250', 'Gastric enteroendocrine cells': '-0.355', 'Mitotic cells (Stomach)': '-0.063', 'Parafollicular cells': '-0.038', 'Thyroid glandular cells': '-0.105', 'Mitotic cells (Thyroid)': '0.052', 'Adrenal cortex cells': '0.188', 'Adrenal medulla cells': '0.047', 'Mitotic cells (Adrenal gland)': '-0.087', 'Minor salivary glandular cells': '0.239', 'Minor salivary gland ductal cells': '-0.263', 'Minor salivary gland basal cells': '0.564', 'Mitotic cells (Minor salivary gland)': '0.575', 'Adipocytes (Minor salivary gland)': '0.299', 'Somatotropes': '-0.188', 'Lactotropes': '-0.361', 'Gonadotropes': '-0.142', 'Corticotropes': '0.095', 'Thyrotropes': '-0.132', 'Undifferentiated cells (Pituitary gland)': '-0.032', 'Mitotic cells (Spleen)': '-0.164', 'Platelets': '-0.169', 'Erythrocytes': '-0.115', 'Hematopoietic stem cells': '-0.168', 'B-cells (Spleen)': '0.081', 'NK-cells (Spleen)': '-0.017', 'Amygdala excitatory': '0.8', 'Cerebellar inhibitory': '0.3', 'Cge interneuron': '0.4', 'Deep-layer corticothalamic and 6b': '1.0', 'Deep-layer intratelencephalic': '1.2', 'Deep-layer near-projecting': '0.2', 'Eccentric medium spiny neuron': '0.9', 'Hippocampal ca1-3': '0.4', 'Hippocampal ca4': '0.1', 'Hippocampal dentate gyrus': '0.3', 'Lamp5-lhx6 and chandelier': '0.1', 'Lower rhombic lip': '0.1', 'Mammillary body': '0.1', 'Medium spiny neuron': '0.8', 'Mge interneuron': '0.9', 'Midbrain-derived inhibitory': '0.1', 'Miscellaneous': '0.6', 'Splatter': '1.3', 'Thalamic excitatory': '0.3', 'Upper rhombic lip': '0.2', 'Upper-layer intratelencephalic': '1.0', 'Astrocyte': '3.7', 'Bergmann glia': '0.8', 'Central nervous system macrophage': '45.6', 'Choroid plexus epithelial cell': '57.6', 'Committed oligodendrocyte precursor': '1.5', 'Ependymal cell': '24.7', 'Oligodendrocyte': '0.2', 'Oligodendrocyte precursor cell': '0.7', 'Endothelial cell': '56.7', 'Pericyte': '8.8', 'Vascular associated smooth muscle cell': '46.9', 'Fibroblast': '10.3', 'Leukocyte': '8.0', 'Basophil': '2.2', 'Eosinophil': '0.5', 'Neutrophil': '7.6', 'Classical monocyte': '484.7', 'Non-classical monocyte': '172.5', 'Intermediate monocyte': '412.1', 'T-reg': '5.5', 'GdT-cell': '0.5', 'MAIT T-cell': '17.0', 'Memory CD4 T-cell': '1.1', 'Naive CD4 T-cell': '3.1', 'Memory CD8 T-cell': '0.6', 'Naive CD8 T-cell': '3.5', 'Memory B-cell': '20.8', 'Naive B-cell': '99.9', 'Plasmacytoid DC': '81.5', 'Myeloid DC': '344.0', 'NK-cell': '4.9', 'Total PBMC': '259.7', 'Vd2 gdTCR': '12.6', 'Memory CD4 T-cell Th1\\/Th17': '56.7', 'Memory CD4 T-cell Th17': '32.8', 'Memory CD4 T-cell Th2': '24.5', 'Non-Vd2 gdTCR': '14.0', 'Memory CD4 T-cell Th1': '42.0', 'Memory CD4 T-cell TFH': '12.6', 'Terminal effector memory CD4 T-cell': '5.2', 'Central memory CD8 T-cell': '4.1', 'Effector memory CD8 T-cell': '6.5', 'Terminal effector memory CD8 T-cell': '10.8', 'Non-switched memory B-cell': '126.9', 'Plasmablast': '79.6', 'Switched memory B-cell': '92.1', 'Exhausted memory B-cell': '109.4', 'Progenitor cell': '19.9', 'Memory T-reg': '14.0', 'Naive CD4 T-cell activated': '83.2', 'Naive CD8 T-cell activated': '40.7', 'Naive T-reg': '3.2'}
1AXC, 2ZVV, 2ZVW, 4RJF, 5E0U, 6CBI, 6CEJ, 6CIV, 6CIX, 6P8H, 7KQ0, 7KQ1, 8GJF
{'Adipose Tissue': 298.2111129568106, 'Adrenal Gland': 93.4060465116279, 'Bladder': 197.83761904761903, 'Blood': 78.93353928955867, 'Blood Vessel': 448.1661423220974, 'Brain': 26.16142089326268, 'Breast': 190.7731372549019, 'Cervix Uteri': 154.54263157894738, 'Colon': 136.42021822849807, 'Esophagus': 163.55013148788927, 'Fallopian Tube': 361.2999999999999, 'Heart': 85.2329837398374, 'Kidney': 85.09125842696629, 'Liver': 87.66353539823008, 'Lung': 274.2942560553633, 'Muscle': 150.03065255292654, 'Nerve': 203.34387722132473, 'Ovary': 296.445, 'Pancreas': 57.98804878048781, 'Pituitary': 149.13120141342756, 'Prostate': 136.3737551020408, 'Salivary Gland': 92.8451172839506, 'Skin': 328.4404422332781, 'Small Intestine': 143.66491978609625, 'Spleen': 44.88352697095436, 'Stomach': 125.28008356545962, 'Testis': 83.37515235457064, 'Thyroid': 131.78820826952526, 'Uterus': 144.23007042253522, 'Vagina': 215.10339743589745}
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[57.54, 53.77, 49.2, 54.65, 47.21, 50.18, 51.36, 57.38, 60.34, 59.02, 58.74, 66.7, 62.76, 72.64, 85.27, 85.76, 90.07, 89.08, 88.6, 88.71, 92.47, 94.27, 91.54, 92.49, 93.33, 94.52, 94.92, 96.58, 96.24, 96.62, 96.78, 97.78, 97.38, 96.94, 96.94, 97.21, 97.04, 95.42, 95.72, 96.32, 95.83, 94.85, 95.47, 96.36, 94.83, 93.7, 93.99, 96.23, 96.61, 94.82, 96.08, 94.34, 93.92, 92.26, 92.37, 91.61, 92.18, 94.69, 92.61, 91.05, 91.84, 93.31, 94.39, 93.61, 94.52, 91.02, 88.51, 86.46, 79.31, 69.5, 71.06, 79.0, 84.36, 86.87, 84.55, 85.75, 86.78, 84.16, 79.43, 73.93, 72.5, 58.53, 58.75, 50.85, 45.0, 47.39, 46.55, 44.31, 49.04, 40.77, 42.1, 41.96, 49.04, 54.49, 40.1, 41.62, 44.88, 39.83, 48.69, 39.11, 40.6, 45.92, 33.81, 36.52, 35.52, 41.52, 42.69, 51.4, 44.01, 54.81, 55.66, 49.71, 55.25, 47.45, 51.51, 47.75, 43.71, 46.45, 60.31, 63.94, 55.05, 51.38, 42.11, 43.98, 44.68, 41.84, 41.46, 49.37, 49.4, 49.36, 46.84, 45.02, 57.78, 46.67, 46.47, 51.42, 62.97, 62.03, 45.33, 62.65, 68.04, 72.15, 74.86, 77.44, 74.32, 74.89, 75.34, 71.44, 62.9, 62.6, 60.64, 60.73, 60.71, 62.32, 62.22, 63.79, 58.88, 59.41, 57.55, 57.62, 60.05, 50.89, 58.14, 66.56]
[0.97, 0.93, 0.96, 0.92, 0.91, 0.77, 0.69, 0.78, 0.8, 0.86, 0.4, 0.89, 0.43, 0.95, 0.47, 0.87, 0.77, 0.39, 0.71, 0.71, 0.78, 0.98, 0.42, 0.89, 0.71, 0.59, 0.67, 0.71, 0.39, 0.53, 0.43, 0.54, 0.46, 0.41, 0.53, 0.59, 0.68, 0.54, 0.51, 0.47, 0.59, 0.41, 0.45, 0.63, 0.21, 0.39, 0.69, 0.77, 0.49, 0.09, 0.18, 0.17, 0.45, 0.72, 0.6, 0.57, 0.46, 0.53, 0.33, 0.98, 0.68, 0.95, 0.42, 0.94, 0.45, 0.87, 0.87, 0.55, 0.89, 0.43, 0.94, 0.81, 0.38, 0.56, 0.79, 0.82, 0.73, 0.38, 0.68, 0.92, 0.66, 0.9, 0.78, 0.91, 0.72, 0.97, 0.93, 0.93, 1.0, 0.85, 1.0, 1.0, 1.0, 0.98, 0.94, 0.9, 0.94, 0.91, 0.95, 0.87, 0.97, 1.0, 0.99, 0.93, 0.99, 0.88, 1.0, 0.98, 0.83, 0.97, 0.65, 0.84, 0.61, 0.66, 0.82, 0.71, 0.8, 0.82, 0.84, 0.83, 0.86, 0.95, 0.94, 0.93, 1.0, 0.99, 1.0, 0.99, 1.0, 1.0, 1.0, 1.0, 0.99, 0.98, 0.94, 0.98, 0.95, 0.95, 0.94, 0.93, 0.93, 0.94, 0.92, 0.95, 0.89, 0.68, 0.87, 0.59, 0.83, 0.83, 0.82, 0.84, 0.79, 0.83, 0.87, 0.87, 0.7, 0.82, 0.76, 0.78, 0.93, 0.98, 0.98, 1.0]
RING finger
Component of a SCF(SKP2)-like complex containing CUL1, SKP1, TRIM21 and SKP2.
SCF
null
IRF8, CALR, CUL1, FBXW11, HSPA5, IKBKB, IRF3, SKP1 , VCP,SKP2, DCP2 ,ULK1, BECN1,GABARAP, GABARAPL1, GABARAPL2 , MAP1LC3C,SQSTM1,IRF3 , NMI, IFI35 , CUL1, TRIM21
USP4, IKBKB, TRIM21, CDKN1B, IRF3, IRF8, MNI
mono, 63
null
UBE2D2, UBE2D1, UBE2E1, UBE2E2
Homotrimer
null
90.718042
0.406716
68.75
0.766829
2,849
P19474
P46527
10323868, RO52_HUMAN, E3Net
UbiNet, UbiBrowser, 31181401
TRIM21
MASAARLTMMWEEVTCPICLDPFVEPVSIECGHSFCQECISQVGKGGGSVCPVCRQRFLLKNLRPNRQLANMVNNLKEISQEAREGTQGERCAVHGERLHLFCEKDGKALCWVCAQSRKHRDHAMVPLEEAAQEYQEKLQVALGELRRKQELAEKLEVEIAIKRADWKKTVETQKSRIHAEFVQQKNFLVEEEQRQLQELEKDEREQLRILGEKEAKLAQQSQALQELISELDRRCHSSALELLQEVIIVLERSESWNLKDLDITSPELRSVCHVPGLKKMLRTCAVHITLDPDTANPWLILSEDRRQVRLGDTQQSIPGNEERFDSYPMVLGAQHFHSGKHYWEVDVTGKEAWDLGVCRDSVRRKGHFLLSSKSGFWTIWLWNKQKYEAGTYPQTPLHLQVPPCQVGIFLDYEAGMVSFYNITDHGSLIYSFSECAFTGPLRPFFSPGFNDGGKNTAPLTLCPLNIGSQGSTDY
Homo sapiens
Cytoplasm, Cytoplasmic vesicle, autophagosome, Nucleus, Cytoplasm, P-body, Cytoplasm, Stress granule
Low tissue specificity
{'Ciliated cells': '3.8', 'Basal respiratory cells': '6.8', 'Club cells': '5.8', 'Ionocytes': '3.7', 'Mucus glandular cells': '4.8', 'Serous glandular cells': '2.3', 'Gastric mucus-secreting cells': '8.8', 'Proximal enterocytes': '8.9', 'Paneth cells': '3.9', 'Distal enterocytes': '8.5', 'Intestinal goblet cells': '8.4', 'Exocrine glandular cells': '-0.716', 'Basal prostatic cells': '5.4', 'Prostatic glandular cells': '5.0', 'Breast glandular cells': '0.298', 'Breast myoepithelial cells': '0.351', 'Glandular and luminal cells': '5.9', 'Secretory cells': '8.4', 'Basal keratinocytes': '3.2', 'Suprabasal keratinocytes': '2.7', 'Basal squamous epithelial cells': '6.4', 'Squamous epithelial cells': '4.3', 'Alveolar cells type 1': '0.116', 'Alveolar cells type 2': '0.115', 'Salivary duct cells': '3.0', 'Ductal cells': '0.700', 'Hepatocytes': '0.503', 'Cholangiocytes': '11.4', 'Proximal tubular cells': '0.175', 'Distal tubular cells': '0.0', 'Collecting duct cells': '5.8', 'Mesothelial cells': '0.451', 'Sertoli cells': '0.479', 'Granulosa cells': '4.8', 'Enteroendocrine cells': '3.7', 'Pancreatic endocrine cells': '3.4', 'Leydig cells': '0.632', 'Excitatory neurons': '0.2', 'Inhibitory neurons': '0.1', 'Cone photoreceptor cells': '0.0', 'Rod photoreceptor cells': '0.0', 'Bipolar cells': '0.7', 'Horizontal cells': '0.6', 'Astrocytes': '0.0', 'Oligodendrocyte precursor cells': '0.9', 'Oligodendrocytes': '0.1', 'Microglial cells': '1.8', 'Muller glia cells': '2.4', 'Schwann cells': '0.099', 'Spermatogonia': '0.401', 'Spermatocytes': '-0.062', 'Early spermatids': '-0.578', 'Late spermatids': '-0.618', 'Oocytes': '1.5', 'Cytotrophoblasts': '6.6', 'Syncytiotrophoblasts': '9.8', 'Extravillous trophoblasts': '10.0', 'Endothelial cells': '7.8', 'Lymphatic endothelial cells': '6.9', 'Cardiomyocytes': '0.335', 'Skeletal myocytes': '-0.080', 'Smooth muscle cells': '6.3', 'Adipocytes': '8.3', 'Melanocytes': '0.101', 'Fibroblasts': '6.5', 'Peritubular cells': '0.579', 'Endometrial stromal cells': '4.5', 'Ovarian stromal cells': '6.7', 'Undifferentiated cells': '5.9', 'T-cells': '9.9', 'B-cells': '8.8', 'Plasma cells': '5.0', 'Nk-cells': '15.1', 'Granulocytes': '6.2', 'Monocytes': '7.8', 'Macrophages': '8.5', 'Hofbauer cells': '9.9', 'Kupffer cells': '10.3', 'Dendritic cells': '8.0', 'Langerhans cells': '0.466', 'Erythroid cells': '-0.084', 'Adipocytes (Subcutaneous)': '-0.368', 'Adipocytes (Visceral)': '-0.167', 'Breast glandular cells (progenitors)': '0.190', 'Adipocytes (Breast)': '-0.382', 'Colon enterocytes': '0.004', 'Colon enteroendocrine cells': '0.196', 'Enteric glia cells': '-0.129', 'Mitotic cells (Colon)': '0.005', 'Mitotic cells (Heart)': '0.486', 'Podocytes': '-0.114', 'Ascending Loop of Henle cells': '0.371', 'Intercalated cells': '-0.097', 'Cholangiocyte': '0.375', 'NK-cells (Liver)': '-0.278', 'Respiratory ciliated cells': '-0.022', 'Mitotic cells (Lung)': '0.157', 'NK-cells (Lung)': '0.110', 'B-cells (Lung)': '-0.155', 'Alpha cells': '0.333', 'Beta cells': '0.161', 'Prostate glandular cells': '-0.162', 'Prostate basal glandular cells': '0.286', 'Urothelial cells': '0.283', 'Keratinocyte (other)': '0.121', 'Keratinocyte (granular)': '-0.008', 'Hair cortex cells': '-0.113', 'Inner root sheath cells': '-0.069', 'Outer root sheath cells': '0.125', 'Sebaceous gland cells': '0.110', 'Eccrine sweat gland cells': '0.070', 'Adipocytes (Skin)': '0.019', 'Mitotic cells (Skin)': '0.236', 'Parietal cells': '-0.609', 'Chief cells': '-0.599', 'Gastric mucous cells': '-0.193', 'Gastric enteroendocrine cells': '-0.441', 'Mitotic cells (Stomach)': '0.261', 'Parafollicular cells': '-0.028', 'Thyroid glandular cells': '0.094', 'Mitotic cells (Thyroid)': '0.242', 'Adrenal cortex cells': '0.619', 'Adrenal medulla cells': '0.063', 'Mitotic cells (Adrenal gland)': '0.483', 'Minor salivary glandular cells': '0.582', 'Minor salivary gland ductal cells': '0.072', 'Minor salivary gland basal cells': '0.229', 'Mitotic cells (Minor salivary gland)': '0.376', 'Adipocytes (Minor salivary gland)': '0.211', 'Somatotropes': '-0.121', 'Lactotropes': '-0.287', 'Gonadotropes': '0.004', 'Corticotropes': '-0.352', 'Thyrotropes': '-0.054', 'Undifferentiated cells (Pituitary gland)': '0.486', 'Mitotic cells (Spleen)': '-0.016', 'Platelets': '0.115', 'Erythrocytes': '0.098', 'Hematopoietic stem cells': '0.042', 'B-cells (Spleen)': '0.028', 'NK-cells (Spleen)': '0.157', 'Amygdala excitatory': '0.1', 'Cerebellar inhibitory': '0.2', 'Cge interneuron': '0.3', 'Deep-layer corticothalamic and 6b': '0.3', 'Deep-layer intratelencephalic': '0.1', 'Deep-layer near-projecting': '0.1', 'Eccentric medium spiny neuron': '0.4', 'Hippocampal ca1-3': '0.5', 'Hippocampal ca4': '0.1', 'Hippocampal dentate gyrus': '0.3', 'Lamp5-lhx6 and chandelier': '0.3', 'Lower rhombic lip': '0.2', 'Mammillary body': '0.4', 'Medium spiny neuron': '0.6', 'Mge interneuron': '0.1', 'Midbrain-derived inhibitory': '0.6', 'Miscellaneous': '0.6', 'Splatter': '0.5', 'Thalamic excitatory': '1.3', 'Upper rhombic lip': '0.1', 'Upper-layer intratelencephalic': '0.1', 'Astrocyte': '1.5', 'Bergmann glia': '1.5', 'Central nervous system macrophage': '6.0', 'Choroid plexus epithelial cell': '2.9', 'Committed oligodendrocyte precursor': '1.0', 'Ependymal cell': '1.3', 'Oligodendrocyte': '0.1', 'Oligodendrocyte precursor cell': '2.3', 'Endothelial cell': '6.4', 'Pericyte': '5.3', 'Vascular associated smooth muscle cell': '3.1', 'Fibroblast': '5.3', 'Leukocyte': '7.4', 'Basophil': '107.0', 'Eosinophil': '312.5', 'Neutrophil': '496.9', 'Classical monocyte': '25.8', 'Non-classical monocyte': '66.1', 'Intermediate monocyte': '117.0', 'T-reg': '72.1', 'GdT-cell': '89.5', 'MAIT T-cell': '61.2', 'Memory CD4 T-cell': '76.8', 'Naive CD4 T-cell': '47.0', 'Memory CD8 T-cell': '81.1', 'Naive CD8 T-cell': '43.5', 'Memory B-cell': '50.4', 'Naive B-cell': '38.5', 'Plasmacytoid DC': '47.5', 'Myeloid DC': '92.2', 'NK-cell': '88.9', 'Total PBMC': '83.8', 'Vd2 gdTCR': '67.8', 'Memory CD4 T-cell Th1\\/Th17': '48.0', 'Memory CD4 T-cell Th17': '54.6', 'Memory CD4 T-cell Th2': '54.8', 'Non-Vd2 gdTCR': '73.7', 'Memory CD4 T-cell Th1': '58.8', 'Memory CD4 T-cell TFH': '61.9', 'Terminal effector memory CD4 T-cell': '72.8', 'Central memory CD8 T-cell': '59.9', 'Effector memory CD8 T-cell': '90.7', 'Terminal effector memory CD8 T-cell': '75.8', 'Non-switched memory B-cell': '52.6', 'Plasmablast': '62.3', 'Switched memory B-cell': '55.8', 'Exhausted memory B-cell': '52.1', 'Progenitor cell': '44.7', 'Memory T-reg': '82.4', 'Naive CD4 T-cell activated': '133.9', 'Naive CD8 T-cell activated': '163.4', 'Naive T-reg': '54.7'}
2IWG, 5JPX, 5OLM, 6FGA, 6S53, 7BBD, 8A58
{'Adipose Tissue': 21.42795099667774, 'Adrenal Gland': 16.707763565891472, 'Bladder': 21.861904761904764, 'Blood': 61.11958557588805, 'Blood Vessel': 22.62928389513109, 'Brain': 4.305000416351249, 'Breast': 20.001740740740743, 'Cervix Uteri': 26.420526315789473, 'Colon': 23.40817458279846, 'Esophagus': 21.74157577854671, 'Fallopian Tube': 25.39, 'Heart': 6.66628106852497, 'Kidney': 13.61479775280899, 'Liver': 10.388, 'Lung': 32.00464878892734, 'Muscle': 3.944284806973848, 'Nerve': 25.39305008077545, 'Ovary': 30.51811111111111, 'Pancreas': 6.808080182926829, 'Pituitary': 12.995699646643107, 'Prostate': 21.00597551020408, 'Salivary Gland': 16.434148148148147, 'Skin': 17.851811498065228, 'Small Intestine': 28.907085561497325, 'Spleen': 50.16024896265561, 'Stomach': 19.072721448467966, 'Testis': 6.377013850415512, 'Thyroid': 21.553307810107196, 'Uterus': 29.83549295774648, 'Vagina': 21.551141025641027}
CDKN1B
MSNVRVSNGSPSLERMDARQAEHPKPSACRNLFGPVDHEELTRDLEKHCRDMEEASQRKWNFDFQNHKPLEGKYEWQEVEKGSLPEFYYRPPRPPKGACKVPAQESQDVSGSRPAAPLIGAPANSEDTHLVDPKTDPSDSQTGLAEQCAGIRKRPATDDSSTQNKRANRTEENVSDGSPNAGSVEQTPKKPGLRRRQT
Homo sapiens
Nucleus, Cytoplasm, Endosome
Low tissue specificity
{'Ciliated cells': '25.5', 'Basal respiratory cells': '19.8', 'Club cells': '33.9', 'Ionocytes': '17.3', 'Mucus glandular cells': '26.7', 'Serous glandular cells': '25.5', 'Gastric mucus-secreting cells': '21.2', 'Proximal enterocytes': '32.3', 'Paneth cells': '26.7', 'Distal enterocytes': '26.4', 'Intestinal goblet cells': '43.2', 'Exocrine glandular cells': '-0.402', 'Basal prostatic cells': '53.1', 'Prostatic glandular cells': '52.2', 'Breast glandular cells': '0.569', 'Breast myoepithelial cells': '0.552', 'Glandular and luminal cells': '35.5', 'Secretory cells': '17.9', 'Basal keratinocytes': '48.9', 'Suprabasal keratinocytes': '45.4', 'Basal squamous epithelial cells': '108.4', 'Squamous epithelial cells': '94.2', 'Alveolar cells type 1': '0.268', 'Alveolar cells type 2': '-0.454', 'Salivary duct cells': '18.6', 'Ductal cells': '0.390', 'Hepatocytes': '0.427', 'Cholangiocytes': '24.8', 'Proximal tubular cells': '0.182', 'Distal tubular cells': '12.3', 'Collecting duct cells': '7.8', 'Mesothelial cells': '0.360', 'Sertoli cells': '0.710', 'Granulosa cells': '34.9', 'Enteroendocrine cells': '46.9', 'Pancreatic endocrine cells': '10.2', 'Leydig cells': '0.570', 'Excitatory neurons': '7.8', 'Inhibitory neurons': '12.8', 'Cone photoreceptor cells': '37.4', 'Rod photoreceptor cells': '22.9', 'Bipolar cells': '40.5', 'Horizontal cells': '33.4', 'Astrocytes': '5.9', 'Oligodendrocyte precursor cells': '5.7', 'Oligodendrocytes': '27.4', 'Microglial cells': '22.4', 'Muller glia cells': '161.0', 'Schwann cells': '0.203', 'Spermatogonia': '0.605', 'Spermatocytes': '0.208', 'Early spermatids': '-0.390', 'Late spermatids': '-0.600', 'Oocytes': '34.6', 'Cytotrophoblasts': '42.9', 'Syncytiotrophoblasts': '39.3', 'Extravillous trophoblasts': '47.9', 'Endothelial cells': '48.3', 'Lymphatic endothelial cells': '35.6', 'Cardiomyocytes': '0.591', 'Skeletal myocytes': '0.056', 'Smooth muscle cells': '59.7', 'Adipocytes': '59.8', 'Melanocytes': '0.231', 'Fibroblasts': '42.7', 'Peritubular cells': '0.470', 'Endometrial stromal cells': '35.7', 'Ovarian stromal cells': '41.7', 'Undifferentiated cells': '47.6', 'T-cells': '190.6', 'B-cells': '126.4', 'Plasma cells': '104.9', 'Nk-cells': '112.4', 'Granulocytes': '60.0', 'Monocytes': '214.6', 'Macrophages': '64.1', 'Hofbauer cells': '29.4', 'Kupffer cells': '45.2', 'Dendritic cells': '34.0', 'Langerhans cells': '0.223', 'Erythroid cells': '0.094', 'Adipocytes (Subcutaneous)': '-0.517', 'Adipocytes (Visceral)': '-0.477', 'Breast glandular cells (progenitors)': '0.368', 'Adipocytes (Breast)': '-0.627', 'Colon enterocytes': '-0.181', 'Colon enteroendocrine cells': '0.273', 'Enteric glia cells': '0.274', 'Mitotic cells (Colon)': '-0.154', 'Mitotic cells (Heart)': '0.432', 'Podocytes': '0.231', 'Ascending Loop of Henle cells': '0.387', 'Intercalated cells': '0.157', 'Cholangiocyte': '0.289', 'NK-cells (Liver)': '-0.151', 'Respiratory ciliated cells': '0.124', 'Mitotic cells (Lung)': '-0.198', 'NK-cells (Lung)': '0.460', 'B-cells (Lung)': '0.301', 'Alpha cells': '0.322', 'Beta cells': '0.167', 'Prostate glandular cells': '-0.143', 'Prostate basal glandular cells': '-0.077', 'Urothelial cells': '-0.007', 'Keratinocyte (other)': '0.422', 'Keratinocyte (granular)': '-0.212', 'Hair cortex cells': '-0.070', 'Inner root sheath cells': '0.013', 'Outer root sheath cells': '0.228', 'Sebaceous gland cells': '-0.068', 'Eccrine sweat gland cells': '0.016', 'Adipocytes (Skin)': '-0.310', 'Mitotic cells (Skin)': '0.433', 'Parietal cells': '-0.533', 'Chief cells': '-0.430', 'Gastric mucous cells': '-0.374', 'Gastric enteroendocrine cells': '-0.297', 'Mitotic cells (Stomach)': '-0.041', 'Parafollicular cells': '0.037', 'Thyroid glandular cells': '0.270', 'Mitotic cells (Thyroid)': '0.117', 'Adrenal cortex cells': '0.464', 'Adrenal medulla cells': '0.086', 'Mitotic cells (Adrenal gland)': '0.262', 'Minor salivary glandular cells': '0.329', 'Minor salivary gland ductal cells': '0.195', 'Minor salivary gland basal cells': '0.233', 'Mitotic cells (Minor salivary gland)': '0.325', 'Adipocytes (Minor salivary gland)': '0.264', 'Somatotropes': '-0.125', 'Lactotropes': '-0.147', 'Gonadotropes': '0.003', 'Corticotropes': '-0.198', 'Thyrotropes': '0.077', 'Undifferentiated cells (Pituitary gland)': '0.405', 'Mitotic cells (Spleen)': '-0.100', 'Platelets': '-0.172', 'Erythrocytes': '-0.125', 'Hematopoietic stem cells': '-0.154', 'B-cells (Spleen)': '0.316', 'NK-cells (Spleen)': '0.264', 'Amygdala excitatory': '7.2', 'Cerebellar inhibitory': '17.8', 'Cge interneuron': '24.8', 'Deep-layer corticothalamic and 6b': '7.4', 'Deep-layer intratelencephalic': '8.1', 'Deep-layer near-projecting': '6.0', 'Eccentric medium spiny neuron': '7.2', 'Hippocampal ca1-3': '6.8', 'Hippocampal ca4': '7.4', 'Hippocampal dentate gyrus': '7.4', 'Lamp5-lhx6 and chandelier': '21.3', 'Lower rhombic lip': '16.1', 'Mammillary body': '17.5', 'Medium spiny neuron': '7.2', 'Mge interneuron': '18.5', 'Midbrain-derived inhibitory': '21.4', 'Miscellaneous': '8.8', 'Splatter': '14.0', 'Thalamic excitatory': '13.8', 'Upper rhombic lip': '38.3', 'Upper-layer intratelencephalic': '7.4', 'Astrocyte': '10.5', 'Bergmann glia': '20.7', 'Central nervous system macrophage': '22.7', 'Choroid plexus epithelial cell': '13.8', 'Committed oligodendrocyte precursor': '20.0', 'Ependymal cell': '19.3', 'Oligodendrocyte': '39.1', 'Oligodendrocyte precursor cell': '18.7', 'Endothelial cell': '55.0', 'Pericyte': '61.5', 'Vascular associated smooth muscle cell': '58.1', 'Fibroblast': '28.4', 'Leukocyte': '63.4', 'Basophil': '146.3', 'Eosinophil': '8.2', 'Neutrophil': '108.3', 'Classical monocyte': '115.3', 'Non-classical monocyte': '165.4', 'Intermediate monocyte': '55.0', 'T-reg': '96.6', 'GdT-cell': '5.8', 'MAIT T-cell': '112.3', 'Memory CD4 T-cell': '7.5', 'Naive CD4 T-cell': '437.3', 'Memory CD8 T-cell': '6.9', 'Naive CD8 T-cell': '336.0', 'Memory B-cell': '6.7', 'Naive B-cell': '180.8', 'Plasmacytoid DC': '17.6', 'Myeloid DC': '69.7', 'NK-cell': '141.8', 'Total PBMC': '64.5', 'Vd2 gdTCR': '53.3', 'Memory CD4 T-cell Th1\\/Th17': '454.5', 'Memory CD4 T-cell Th17': '375.9', 'Memory CD4 T-cell Th2': '438.1', 'Non-Vd2 gdTCR': '73.3', 'Memory CD4 T-cell Th1': '377.8', 'Memory CD4 T-cell TFH': '436.6', 'Terminal effector memory CD4 T-cell': '50.5', 'Central memory CD8 T-cell': '100.1', 'Effector memory CD8 T-cell': '58.9', 'Terminal effector memory CD8 T-cell': '54.5', 'Non-switched memory B-cell': '46.9', 'Plasmablast': '53.8', 'Switched memory B-cell': '50.0', 'Exhausted memory B-cell': '46.7', 'Progenitor cell': '20.4', 'Memory T-reg': '447.2', 'Naive CD4 T-cell activated': '97.4', 'Naive CD8 T-cell activated': '93.6', 'Naive T-reg': '713.8'}
1H27, 1JSU, 2AST, 5UQ3, 6ATH, 6P8E, 6P8F, 6P8G, 7B5L, 7B5M, 7B5R, 7OR8, 7ORG, 7ORH, 7ORS, 7ORT, 8BYA, 8BYL, 8BZO
{'Adipose Tissue': 89.28307308970099, 'Adrenal Gland': 49.201007751937986, 'Bladder': 63.78047619047619, 'Blood': 68.55482454251884, 'Blood Vessel': 122.23632958801498, 'Brain': 69.23933762301286, 'Breast': 97.70257080610024, 'Cervix Uteri': 117.59052631578946, 'Colon': 69.30115532734274, 'Esophagus': 56.005737024221446, 'Fallopian Tube': 110.25333333333332, 'Heart': 23.158851335656216, 'Kidney': 27.414337078651688, 'Liver': 24.55152654867257, 'Lung': 82.52216262975779, 'Muscle': 43.84146575342466, 'Nerve': 139.4383198707593, 'Ovary': 106.24844444444444, 'Pancreas': 16.517003048780488, 'Pituitary': 49.177385159010605, 'Prostate': 57.263387755102045, 'Salivary Gland': 48.443765432098765, 'Skin': 63.90882808181316, 'Small Intestine': 65.75898395721926, 'Spleen': 75.991244813278, 'Stomach': 39.69147632311978, 'Testis': 51.55265927977839, 'Thyroid': 78.49858499234303, 'Uterus': 118.09823943661972, 'Vagina': 94.36891025641025}
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[48.29, 68.93, 66.41, 74.75, 70.67, 66.43, 66.18, 56.59, 61.92, 59.55, 63.59, 63.42, 62.99, 64.16, 62.97, 61.12, 58.95, 60.2, 59.66, 56.72, 60.4, 70.98, 74.85, 84.62, 87.89, 91.85, 92.87, 95.19, 92.91, 95.02, 95.09, 96.62, 96.97, 95.71, 96.04, 96.77, 96.75, 97.72, 97.44, 97.03, 97.04, 97.42, 97.94, 97.67, 97.19, 96.96, 96.84, 96.37, 94.07, 95.33, 95.63, 94.55, 93.59, 94.76, 95.43, 94.06, 94.0, 93.64, 95.58, 96.11, 94.69, 94.61, 94.06, 92.1, 90.74, 92.39, 92.44, 92.69, 94.65, 92.86, 91.85, 92.07, 94.25, 94.97, 94.89, 95.57, 93.06, 91.38, 92.13, 90.64, 88.87, 89.31, 90.74, 90.09, 93.42, 92.68, 93.13, 92.62, 91.19, 93.1, 92.21, 91.57, 89.31, 85.55, 83.44, 71.71, 63.51, 56.71, 47.22, 55.45, 55.36, 48.19, 50.67, 49.74, 40.28, 51.95, 55.26, 45.66, 56.04, 44.07, 44.88, 45.7, 54.49, 51.23, 45.36, 46.31, 44.06, 48.67, 46.69, 40.62, 43.42, 39.19, 42.9, 48.83, 57.12, 53.02, 53.13, 53.48, 46.54, 51.4, 52.85, 47.94, 47.75, 43.8, 49.24, 54.66, 50.57, 51.6, 51.03, 52.41, 50.53, 51.33, 37.73, 48.48, 46.83, 52.89, 43.6, 44.83, 41.31, 48.53, 53.99, 50.96, 60.43, 67.65, 59.28, 53.83, 61.34, 47.04, 56.3, 48.25, 53.64, 52.16, 49.62, 48.69, 69.04, 44.6, 56.99, 44.54, 62.24, 45.39, 61.18, 62.23, 44.32, 54.33, 44.6, 56.06, 41.21, 54.73, 50.96, 45.35, 49.77, 40.09, 56.35, 59.39, 64.82, 64.01, 67.82, 69.08, 67.9, 71.82, 69.26, 65.6, 65.19, 66.37, 70.91, 69.71, 71.15, 65.53]
[1.0, 0.91, 0.95, 0.86, 0.94, 0.9, 0.94, 0.98, 0.79, 0.92, 0.9, 0.82, 0.81, 0.82, 0.84, 0.86, 0.85, 0.83, 0.87, 0.9, 0.72, 0.83, 0.9, 0.85, 0.81, 0.62, 0.69, 0.78, 0.62, 0.68, 0.69, 0.82, 0.98, 0.41, 0.96, 0.6, 0.52, 0.65, 0.74, 0.51, 0.42, 0.47, 0.62, 0.55, 0.54, 0.52, 0.53, 0.59, 0.48, 0.6, 0.4, 0.57, 0.45, 0.41, 0.54, 0.35, 0.3, 0.68, 0.65, 0.47, 0.07, 0.18, 0.18, 0.44, 0.8, 0.64, 0.71, 0.65, 0.59, 0.43, 0.98, 0.68, 0.71, 0.44, 0.85, 0.45, 0.79, 1.0, 0.59, 0.81, 0.62, 0.8, 0.64, 0.45, 0.59, 0.43, 0.81, 0.76, 0.38, 0.62, 0.83, 0.93, 0.92, 0.88, 0.76, 0.95, 0.8, 0.7, 0.8, 0.91, 0.84, 0.79, 0.88, 0.83, 0.84, 0.84, 0.88, 0.99, 1.0, 1.0, 1.0, 0.99, 0.98, 0.97, 0.85, 0.87, 0.8, 0.92, 0.91, 0.93, 0.99, 1.0, 0.99, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 0.98, 0.96, 0.97, 0.95, 1.0, 0.99, 0.99, 0.95, 0.97, 0.91, 0.97, 0.93, 0.96, 0.98, 1.0, 0.91, 0.98, 0.81, 0.92, 0.86, 0.88, 0.91, 0.89, 0.94, 0.87, 0.94, 0.91, 0.9, 0.83, 0.86, 0.81, 0.89, 0.99, 0.93, 1.0, 0.99, 0.99, 0.99, 0.91, 1.0, 0.77, 0.95, 1.0, 0.92, 0.99, 0.98, 1.0, 0.99, 1.0, 0.99, 0.99, 0.98, 0.94, 0.86, 0.89, 0.86, 0.84, 0.91, 0.94, 0.96, 0.91, 0.83, 0.93, 0.93, 0.88, 0.97, 0.87, 0.99]
RING finger
Component of a SCF(SKP2)-like complex containing CUL1, SKP1, TRIM21 and SKP2.
SCF
null
IRF8, CALR, CUL1, FBXW11, HSPA5, IKBKB, IRF3, SKP1 , VCP,SKP2, DCP2 ,ULK1, BECN1,GABARAP, GABARAPL1, GABARAPL2 , MAP1LC3C,SQSTM1,IRF3 , NMI, IFI35 , CUL1, TRIM21
USP4, IKBKB, TRIM21, CDKN1B, IRF3, IRF8, MNI
mono, 63
null
UBE2D2, UBE2D1, UBE2E1, UBE2E2
Homotrimer
null
90.718042
0.406716
69.051313
0.809899
2,742
P19474
P49915
33742136
UbiBrowser
TRIM21
MASAARLTMMWEEVTCPICLDPFVEPVSIECGHSFCQECISQVGKGGGSVCPVCRQRFLLKNLRPNRQLANMVNNLKEISQEAREGTQGERCAVHGERLHLFCEKDGKALCWVCAQSRKHRDHAMVPLEEAAQEYQEKLQVALGELRRKQELAEKLEVEIAIKRADWKKTVETQKSRIHAEFVQQKNFLVEEEQRQLQELEKDEREQLRILGEKEAKLAQQSQALQELISELDRRCHSSALELLQEVIIVLERSESWNLKDLDITSPELRSVCHVPGLKKMLRTCAVHITLDPDTANPWLILSEDRRQVRLGDTQQSIPGNEERFDSYPMVLGAQHFHSGKHYWEVDVTGKEAWDLGVCRDSVRRKGHFLLSSKSGFWTIWLWNKQKYEAGTYPQTPLHLQVPPCQVGIFLDYEAGMVSFYNITDHGSLIYSFSECAFTGPLRPFFSPGFNDGGKNTAPLTLCPLNIGSQGSTDY
Homo sapiens
Cytoplasm, Cytoplasmic vesicle, autophagosome, Nucleus, Cytoplasm, P-body, Cytoplasm, Stress granule
Low tissue specificity
{'Ciliated cells': '3.8', 'Basal respiratory cells': '6.8', 'Club cells': '5.8', 'Ionocytes': '3.7', 'Mucus glandular cells': '4.8', 'Serous glandular cells': '2.3', 'Gastric mucus-secreting cells': '8.8', 'Proximal enterocytes': '8.9', 'Paneth cells': '3.9', 'Distal enterocytes': '8.5', 'Intestinal goblet cells': '8.4', 'Exocrine glandular cells': '-0.716', 'Basal prostatic cells': '5.4', 'Prostatic glandular cells': '5.0', 'Breast glandular cells': '0.298', 'Breast myoepithelial cells': '0.351', 'Glandular and luminal cells': '5.9', 'Secretory cells': '8.4', 'Basal keratinocytes': '3.2', 'Suprabasal keratinocytes': '2.7', 'Basal squamous epithelial cells': '6.4', 'Squamous epithelial cells': '4.3', 'Alveolar cells type 1': '0.116', 'Alveolar cells type 2': '0.115', 'Salivary duct cells': '3.0', 'Ductal cells': '0.700', 'Hepatocytes': '0.503', 'Cholangiocytes': '11.4', 'Proximal tubular cells': '0.175', 'Distal tubular cells': '0.0', 'Collecting duct cells': '5.8', 'Mesothelial cells': '0.451', 'Sertoli cells': '0.479', 'Granulosa cells': '4.8', 'Enteroendocrine cells': '3.7', 'Pancreatic endocrine cells': '3.4', 'Leydig cells': '0.632', 'Excitatory neurons': '0.2', 'Inhibitory neurons': '0.1', 'Cone photoreceptor cells': '0.0', 'Rod photoreceptor cells': '0.0', 'Bipolar cells': '0.7', 'Horizontal cells': '0.6', 'Astrocytes': '0.0', 'Oligodendrocyte precursor cells': '0.9', 'Oligodendrocytes': '0.1', 'Microglial cells': '1.8', 'Muller glia cells': '2.4', 'Schwann cells': '0.099', 'Spermatogonia': '0.401', 'Spermatocytes': '-0.062', 'Early spermatids': '-0.578', 'Late spermatids': '-0.618', 'Oocytes': '1.5', 'Cytotrophoblasts': '6.6', 'Syncytiotrophoblasts': '9.8', 'Extravillous trophoblasts': '10.0', 'Endothelial cells': '7.8', 'Lymphatic endothelial cells': '6.9', 'Cardiomyocytes': '0.335', 'Skeletal myocytes': '-0.080', 'Smooth muscle cells': '6.3', 'Adipocytes': '8.3', 'Melanocytes': '0.101', 'Fibroblasts': '6.5', 'Peritubular cells': '0.579', 'Endometrial stromal cells': '4.5', 'Ovarian stromal cells': '6.7', 'Undifferentiated cells': '5.9', 'T-cells': '9.9', 'B-cells': '8.8', 'Plasma cells': '5.0', 'Nk-cells': '15.1', 'Granulocytes': '6.2', 'Monocytes': '7.8', 'Macrophages': '8.5', 'Hofbauer cells': '9.9', 'Kupffer cells': '10.3', 'Dendritic cells': '8.0', 'Langerhans cells': '0.466', 'Erythroid cells': '-0.084', 'Adipocytes (Subcutaneous)': '-0.368', 'Adipocytes (Visceral)': '-0.167', 'Breast glandular cells (progenitors)': '0.190', 'Adipocytes (Breast)': '-0.382', 'Colon enterocytes': '0.004', 'Colon enteroendocrine cells': '0.196', 'Enteric glia cells': '-0.129', 'Mitotic cells (Colon)': '0.005', 'Mitotic cells (Heart)': '0.486', 'Podocytes': '-0.114', 'Ascending Loop of Henle cells': '0.371', 'Intercalated cells': '-0.097', 'Cholangiocyte': '0.375', 'NK-cells (Liver)': '-0.278', 'Respiratory ciliated cells': '-0.022', 'Mitotic cells (Lung)': '0.157', 'NK-cells (Lung)': '0.110', 'B-cells (Lung)': '-0.155', 'Alpha cells': '0.333', 'Beta cells': '0.161', 'Prostate glandular cells': '-0.162', 'Prostate basal glandular cells': '0.286', 'Urothelial cells': '0.283', 'Keratinocyte (other)': '0.121', 'Keratinocyte (granular)': '-0.008', 'Hair cortex cells': '-0.113', 'Inner root sheath cells': '-0.069', 'Outer root sheath cells': '0.125', 'Sebaceous gland cells': '0.110', 'Eccrine sweat gland cells': '0.070', 'Adipocytes (Skin)': '0.019', 'Mitotic cells (Skin)': '0.236', 'Parietal cells': '-0.609', 'Chief cells': '-0.599', 'Gastric mucous cells': '-0.193', 'Gastric enteroendocrine cells': '-0.441', 'Mitotic cells (Stomach)': '0.261', 'Parafollicular cells': '-0.028', 'Thyroid glandular cells': '0.094', 'Mitotic cells (Thyroid)': '0.242', 'Adrenal cortex cells': '0.619', 'Adrenal medulla cells': '0.063', 'Mitotic cells (Adrenal gland)': '0.483', 'Minor salivary glandular cells': '0.582', 'Minor salivary gland ductal cells': '0.072', 'Minor salivary gland basal cells': '0.229', 'Mitotic cells (Minor salivary gland)': '0.376', 'Adipocytes (Minor salivary gland)': '0.211', 'Somatotropes': '-0.121', 'Lactotropes': '-0.287', 'Gonadotropes': '0.004', 'Corticotropes': '-0.352', 'Thyrotropes': '-0.054', 'Undifferentiated cells (Pituitary gland)': '0.486', 'Mitotic cells (Spleen)': '-0.016', 'Platelets': '0.115', 'Erythrocytes': '0.098', 'Hematopoietic stem cells': '0.042', 'B-cells (Spleen)': '0.028', 'NK-cells (Spleen)': '0.157', 'Amygdala excitatory': '0.1', 'Cerebellar inhibitory': '0.2', 'Cge interneuron': '0.3', 'Deep-layer corticothalamic and 6b': '0.3', 'Deep-layer intratelencephalic': '0.1', 'Deep-layer near-projecting': '0.1', 'Eccentric medium spiny neuron': '0.4', 'Hippocampal ca1-3': '0.5', 'Hippocampal ca4': '0.1', 'Hippocampal dentate gyrus': '0.3', 'Lamp5-lhx6 and chandelier': '0.3', 'Lower rhombic lip': '0.2', 'Mammillary body': '0.4', 'Medium spiny neuron': '0.6', 'Mge interneuron': '0.1', 'Midbrain-derived inhibitory': '0.6', 'Miscellaneous': '0.6', 'Splatter': '0.5', 'Thalamic excitatory': '1.3', 'Upper rhombic lip': '0.1', 'Upper-layer intratelencephalic': '0.1', 'Astrocyte': '1.5', 'Bergmann glia': '1.5', 'Central nervous system macrophage': '6.0', 'Choroid plexus epithelial cell': '2.9', 'Committed oligodendrocyte precursor': '1.0', 'Ependymal cell': '1.3', 'Oligodendrocyte': '0.1', 'Oligodendrocyte precursor cell': '2.3', 'Endothelial cell': '6.4', 'Pericyte': '5.3', 'Vascular associated smooth muscle cell': '3.1', 'Fibroblast': '5.3', 'Leukocyte': '7.4', 'Basophil': '107.0', 'Eosinophil': '312.5', 'Neutrophil': '496.9', 'Classical monocyte': '25.8', 'Non-classical monocyte': '66.1', 'Intermediate monocyte': '117.0', 'T-reg': '72.1', 'GdT-cell': '89.5', 'MAIT T-cell': '61.2', 'Memory CD4 T-cell': '76.8', 'Naive CD4 T-cell': '47.0', 'Memory CD8 T-cell': '81.1', 'Naive CD8 T-cell': '43.5', 'Memory B-cell': '50.4', 'Naive B-cell': '38.5', 'Plasmacytoid DC': '47.5', 'Myeloid DC': '92.2', 'NK-cell': '88.9', 'Total PBMC': '83.8', 'Vd2 gdTCR': '67.8', 'Memory CD4 T-cell Th1\\/Th17': '48.0', 'Memory CD4 T-cell Th17': '54.6', 'Memory CD4 T-cell Th2': '54.8', 'Non-Vd2 gdTCR': '73.7', 'Memory CD4 T-cell Th1': '58.8', 'Memory CD4 T-cell TFH': '61.9', 'Terminal effector memory CD4 T-cell': '72.8', 'Central memory CD8 T-cell': '59.9', 'Effector memory CD8 T-cell': '90.7', 'Terminal effector memory CD8 T-cell': '75.8', 'Non-switched memory B-cell': '52.6', 'Plasmablast': '62.3', 'Switched memory B-cell': '55.8', 'Exhausted memory B-cell': '52.1', 'Progenitor cell': '44.7', 'Memory T-reg': '82.4', 'Naive CD4 T-cell activated': '133.9', 'Naive CD8 T-cell activated': '163.4', 'Naive T-reg': '54.7'}
2IWG, 5JPX, 5OLM, 6FGA, 6S53, 7BBD, 8A58
{'Adipose Tissue': 21.42795099667774, 'Adrenal Gland': 16.707763565891472, 'Bladder': 21.861904761904764, 'Blood': 61.11958557588805, 'Blood Vessel': 22.62928389513109, 'Brain': 4.305000416351249, 'Breast': 20.001740740740743, 'Cervix Uteri': 26.420526315789473, 'Colon': 23.40817458279846, 'Esophagus': 21.74157577854671, 'Fallopian Tube': 25.39, 'Heart': 6.66628106852497, 'Kidney': 13.61479775280899, 'Liver': 10.388, 'Lung': 32.00464878892734, 'Muscle': 3.944284806973848, 'Nerve': 25.39305008077545, 'Ovary': 30.51811111111111, 'Pancreas': 6.808080182926829, 'Pituitary': 12.995699646643107, 'Prostate': 21.00597551020408, 'Salivary Gland': 16.434148148148147, 'Skin': 17.851811498065228, 'Small Intestine': 28.907085561497325, 'Spleen': 50.16024896265561, 'Stomach': 19.072721448467966, 'Testis': 6.377013850415512, 'Thyroid': 21.553307810107196, 'Uterus': 29.83549295774648, 'Vagina': 21.551141025641027}
GMPS
MALCNGDSKLENAGGDLKDGHHHYEGAVVILDAGAQYGKVIDRRVRELFVQSEIFPLETPAFAIKEQGFRAIIISGGPNSVYAEDAPWFDPAIFTIGKPVLGICYGMQMMNKVFGGTVHKKSVREDGVFNISVDNTCSLFRGLQKEEVVLLTHGDSVDKVADGFKVVARSGNIVAGIANESKKLYGAQFHPEVGLTENGKVILKNFLYDIAGCSGTFTVQNRELECIREIKERVGTSKVLVLLSGGVDSTVCTALLNRALNQEQVIAVHIDNGFMRKRESQSVEEALKKLGIQVKVINAAHSFYNGTTTLPISDEDRTPRKRISKTLNMTTSPEEKRKIIGDTFVKIANEVIGEMNLKPEEVFLAQGTLRPDLIESASLVASGKAELIKTHHNDTELIRKLREEGKVIEPLKDFHKDEVRILGRELGLPEELVSRHPFPGPGLAIRVICAEEPYICKDFPETNNILKIVADFSASVKKPHTLLQRVKACTTEEDQEKLMQITSLHSLNAFLLPIKTVGVQGDCRSYSYVCGISSKDEPDWESLIFLARLIPRMCHNVNRVVYIFGPPVKEPPTDVTPTFLTTGVLSTLRQADFEAHNILRESGYAGKISQMPVILTPLHFDRDPLQKQPSCQRSVVIRTFITSDFMTGIPATPGNEIPVEVVLKMVTEIKKIPGISRIMYDLTSKPPGTTEWE
Homo sapiens
Cytoplasm, cytosol
Tissue enhanced (testis)
{'Ciliated cells': '14.9', 'Basal respiratory cells': '36.4', 'Club cells': '25.1', 'Ionocytes': '18.4', 'Mucus glandular cells': '23.6', 'Serous glandular cells': '41.2', 'Gastric mucus-secreting cells': '22.4', 'Proximal enterocytes': '17.6', 'Paneth cells': '9.1', 'Distal enterocytes': '11.4', 'Intestinal goblet cells': '21.8', 'Exocrine glandular cells': '-0.617', 'Basal prostatic cells': '30.8', 'Prostatic glandular cells': '31.6', 'Breast glandular cells': '0.501', 'Breast myoepithelial cells': '0.571', 'Glandular and luminal cells': '17.6', 'Secretory cells': '36.7', 'Basal keratinocytes': '38.2', 'Suprabasal keratinocytes': '37.3', 'Basal squamous epithelial cells': '31.2', 'Squamous epithelial cells': '25.2', 'Alveolar cells type 1': '0.072', 'Alveolar cells type 2': '-0.155', 'Salivary duct cells': '31.4', 'Ductal cells': '0.462', 'Hepatocytes': '0.551', 'Cholangiocytes': '11.4', 'Proximal tubular cells': '0.158', 'Distal tubular cells': '15.4', 'Collecting duct cells': '9.7', 'Mesothelial cells': '0.457', 'Sertoli cells': '-0.258', 'Granulosa cells': '22.4', 'Enteroendocrine cells': '15.3', 'Pancreatic endocrine cells': '35.7', 'Leydig cells': '-0.340', 'Excitatory neurons': '39.5', 'Inhibitory neurons': '39.9', 'Cone photoreceptor cells': '10.2', 'Rod photoreceptor cells': '5.0', 'Bipolar cells': '16.6', 'Horizontal cells': '20.1', 'Astrocytes': '18.6', 'Oligodendrocyte precursor cells': '28.3', 'Oligodendrocytes': '29.4', 'Microglial cells': '21.5', 'Muller glia cells': '16.5', 'Schwann cells': '0.137', 'Spermatogonia': '0.002', 'Spermatocytes': '0.380', 'Early spermatids': '0.866', 'Late spermatids': '0.438', 'Oocytes': '63.2', 'Cytotrophoblasts': '44.1', 'Syncytiotrophoblasts': '29.3', 'Extravillous trophoblasts': '50.3', 'Endothelial cells': '27.0', 'Lymphatic endothelial cells': '27.1', 'Cardiomyocytes': '0.591', 'Skeletal myocytes': '-0.284', 'Smooth muscle cells': '29.0', 'Adipocytes': '21.0', 'Melanocytes': '0.247', 'Fibroblasts': '29.1', 'Peritubular cells': '-0.225', 'Endometrial stromal cells': '35.6', 'Ovarian stromal cells': '20.7', 'Undifferentiated cells': '40.6', 'T-cells': '31.8', 'B-cells': '23.0', 'Plasma cells': '22.3', 'Nk-cells': '23.8', 'Granulocytes': '30.8', 'Monocytes': '25.4', 'Macrophages': '24.2', 'Hofbauer cells': '25.4', 'Kupffer cells': '12.8', 'Dendritic cells': '20.6', 'Langerhans cells': '0.270', 'Erythroid cells': '-0.067', 'Adipocytes (Subcutaneous)': '-0.392', 'Adipocytes (Visceral)': '-0.416', 'Breast glandular cells (progenitors)': '0.393', 'Adipocytes (Breast)': '-0.562', 'Colon enterocytes': '-0.150', 'Colon enteroendocrine cells': '0.256', 'Enteric glia cells': '0.046', 'Mitotic cells (Colon)': '-0.039', 'Mitotic cells (Heart)': '0.518', 'Podocytes': '-0.063', 'Ascending Loop of Henle cells': '0.435', 'Intercalated cells': '0.027', 'Cholangiocyte': '0.339', 'NK-cells (Liver)': '-0.311', 'Respiratory ciliated cells': '-0.100', 'Mitotic cells (Lung)': '0.054', 'NK-cells (Lung)': '0.176', 'B-cells (Lung)': '0.016', 'Alpha cells': '0.328', 'Beta cells': '0.155', 'Prostate glandular cells': '-0.242', 'Prostate basal glandular cells': '0.119', 'Urothelial cells': '0.161', 'Keratinocyte (other)': '0.485', 'Keratinocyte (granular)': '-0.126', 'Hair cortex cells': '-0.137', 'Inner root sheath cells': '-0.035', 'Outer root sheath cells': '0.032', 'Sebaceous gland cells': '0.042', 'Eccrine sweat gland cells': '-0.117', 'Adipocytes (Skin)': '-0.279', 'Mitotic cells (Skin)': '0.374', 'Parietal cells': '-0.590', 'Chief cells': '-0.395', 'Gastric mucous cells': '-0.340', 'Gastric enteroendocrine cells': '-0.328', 'Mitotic cells (Stomach)': '0.094', 'Parafollicular cells': '0.110', 'Thyroid glandular cells': '0.361', 'Mitotic cells (Thyroid)': '0.009', 'Adrenal cortex cells': '0.626', 'Adrenal medulla cells': '0.055', 'Mitotic cells (Adrenal gland)': '0.373', 'Minor salivary glandular cells': '0.403', 'Minor salivary gland ductal cells': '0.193', 'Minor salivary gland basal cells': '0.415', 'Mitotic cells (Minor salivary gland)': '0.310', 'Adipocytes (Minor salivary gland)': '0.087', 'Somatotropes': '0.052', 'Lactotropes': '0.119', 'Gonadotropes': '0.023', 'Corticotropes': '-0.115', 'Thyrotropes': '0.172', 'Undifferentiated cells (Pituitary gland)': '0.125', 'Mitotic cells (Spleen)': '-0.103', 'Platelets': '-0.182', 'Erythrocytes': '-0.065', 'Hematopoietic stem cells': '-0.199', 'B-cells (Spleen)': '0.251', 'NK-cells (Spleen)': '0.256', 'Amygdala excitatory': '46.8', 'Cerebellar inhibitory': '74.7', 'Cge interneuron': '62.5', 'Deep-layer corticothalamic and 6b': '52.3', 'Deep-layer intratelencephalic': '44.8', 'Deep-layer near-projecting': '51.4', 'Eccentric medium spiny neuron': '65.8', 'Hippocampal ca1-3': '51.9', 'Hippocampal ca4': '38.7', 'Hippocampal dentate gyrus': '54.8', 'Lamp5-lhx6 and chandelier': '60.0', 'Lower rhombic lip': '70.0', 'Mammillary body': '81.7', 'Medium spiny neuron': '61.6', 'Mge interneuron': '58.5', 'Midbrain-derived inhibitory': '47.8', 'Miscellaneous': '56.4', 'Splatter': '59.9', 'Thalamic excitatory': '64.8', 'Upper rhombic lip': '106.2', 'Upper-layer intratelencephalic': '48.4', 'Astrocyte': '54.5', 'Bergmann glia': '62.8', 'Central nervous system macrophage': '68.4', 'Choroid plexus epithelial cell': '134.2', 'Committed oligodendrocyte precursor': '44.0', 'Ependymal cell': '53.6', 'Oligodendrocyte': '52.1', 'Oligodendrocyte precursor cell': '59.9', 'Endothelial cell': '58.3', 'Pericyte': '68.6', 'Vascular associated smooth muscle cell': '59.6', 'Fibroblast': '61.5', 'Leukocyte': '65.1', 'Basophil': '41.5', 'Eosinophil': '11.5', 'Neutrophil': '4.3', 'Classical monocyte': '12.0', 'Non-classical monocyte': '24.8', 'Intermediate monocyte': '69.5', 'T-reg': '68.6', 'GdT-cell': '24.7', 'MAIT T-cell': '80.7', 'Memory CD4 T-cell': '23.6', 'Naive CD4 T-cell': '31.0', 'Memory CD8 T-cell': '22.3', 'Naive CD8 T-cell': '24.1', 'Memory B-cell': '16.0', 'Naive B-cell': '17.0', 'Plasmacytoid DC': '76.5', 'Myeloid DC': '67.9', 'NK-cell': '27.1', 'Total PBMC': '55.1', 'Vd2 gdTCR': '72.8', 'Memory CD4 T-cell TFH': '25.1', 'Memory CD4 T-cell Th2': '31.8', 'Memory CD4 T-cell Th17': '30.8', 'Memory CD4 T-cell Th1\\/Th17': '32.6', 'Non-Vd2 gdTCR': '73.6', 'Memory CD4 T-cell Th1': '27.4', 'Terminal effector memory CD4 T-cell': '75.5', 'Central memory CD8 T-cell': '71.2', 'Effector memory CD8 T-cell': '77.9', 'Terminal effector memory CD8 T-cell': '66.8', 'Switched memory B-cell': '51.5', 'Plasmablast': '42.8', 'Non-switched memory B-cell': '46.7', 'Exhausted memory B-cell': '50.8', 'Progenitor cell': '64.3', 'Naive CD4 T-cell activated': '33.3', 'Naive CD8 T-cell activated': '34.2', 'Memory T-reg': '24.9', 'Naive T-reg': '29.4'}
2VPI, 2VXO
{'Adipose Tissue': 12.93343438538206, 'Adrenal Gland': 12.16782945736434, 'Bladder': 14.530666666666669, 'Blood': 9.262314854682456, 'Blood Vessel': 17.065539325842696, 'Brain': 8.396625738077214, 'Breast': 13.67073202614379, 'Cervix Uteri': 20.30421052631579, 'Colon': 11.627983311938385, 'Esophagus': 12.070811764705883, 'Fallopian Tube': 17.040000000000003, 'Heart': 5.010834262485482, 'Kidney': 5.67808988764045, 'Liver': 3.8461734513274335, 'Lung': 13.950162629757786, 'Muscle': 5.950008717310087, 'Nerve': 20.056009693053312, 'Ovary': 17.43597777777778, 'Pancreas': 6.603685975609756, 'Pituitary': 11.949074204946998, 'Prostate': 12.952408163265307, 'Salivary Gland': 12.453222222222225, 'Skin': 18.792415699281374, 'Small Intestine': 10.038604278074867, 'Spleen': 10.509095435684648, 'Stomach': 9.599855153203343, 'Testis': 51.16567867036011, 'Thyroid': 14.286551301684533, 'Uterus': 19.476690140845072, 'Vagina': 17.100416666666668}
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[1.0, 0.91, 0.88, 0.89, 0.82, 0.75, 0.85, 0.83, 0.85, 0.85, 0.91, 0.8, 0.9, 0.75, 0.71, 0.76, 0.75, 0.83, 0.72, 0.86, 0.63, 0.51, 0.66, 0.26, 0.73, 0.36, 0.01, 0.0, 0.0, 0.0, 0.0, 0.28, 0.1, 0.34, 0.5, 0.52, 0.27, 0.0, 0.5, 0.35, 0.0, 0.0, 0.41, 0.21, 0.0, 0.04, 0.27, 0.14, 0.48, 0.01, 0.31, 0.0, 0.16, 0.29, 0.23, 0.63, 0.01, 0.47, 0.11, 0.35, 0.02, 0.62, 0.21, 0.01, 0.55, 0.61, 0.22, 0.17, 0.01, 0.45, 0.01, 0.0, 0.0, 0.0, 0.0, 0.01, 0.24, 0.74, 0.34, 0.31, 0.06, 0.53, 0.32, 0.97, 0.68, 0.34, 0.26, 0.66, 0.23, 0.19, 0.45, 0.32, 0.0, 0.05, 0.68, 0.22, 0.83, 0.26, 0.07, 0.0, 0.01, 0.0, 0.0, 0.06, 0.02, 0.0, 0.0, 0.04, 0.01, 0.0, 0.0, 0.39, 0.4, 0.2, 0.53, 0.09, 0.3, 0.03, 0.55, 0.83, 0.43, 0.98, 0.74, 0.69, 0.19, 0.51, 0.24, 0.51, 0.31, 0.65, 0.02, 0.49, 0.12, 0.37, 0.27, 0.8, 0.03, 0.28, 0.0, 0.0, 0.62, 0.87, 0.11, 0.71, 0.73, 0.78, 0.06, 0.26, 0.02, 0.14, 0.0, 0.28, 0.07, 0.34, 0.12, 0.01, 0.04, 0.63, 0.53, 0.24, 0.04, 0.68, 0.67, 0.1, 0.74, 0.22, 0.06, 0.03, 0.46, 0.09, 0.72, 0.89, 0.11, 0.1, 0.0, 0.0, 0.0, 0.04, 0.07, 0.4, 0.87, 0.53, 0.43, 0.0, 0.02, 0.0, 0.01, 0.0, 0.0, 0.0, 0.01, 0.0, 0.21, 0.72, 0.54, 0.03, 0.7, 0.36, 0.01, 0.48, 0.35, 0.03, 0.0, 0.53, 0.07, 0.0, 0.0, 0.3, 0.61, 0.05, 0.04, 0.46, 0.1, 0.53, 0.35, 0.55, 0.14, 0.2, 0.12, 0.51, 0.45, 0.05, 0.08, 0.6, 0.41, 0.12, 0.12, 0.47, 0.4, 0.04, 0.53, 0.65, 0.53, 0.04, 0.47, 0.89, 0.21, 0.44, 0.0, 0.0, 0.02, 0.13, 0.01, 0.54, 0.05, 0.34, 0.14, 0.26, 0.09, 0.0, 0.0, 0.0, 0.0, 0.05, 0.0, 0.0, 0.19, 0.44, 0.08, 0.11, 0.66, 0.58, 0.84, 0.1, 0.07, 0.18, 0.02, 0.01, 0.0, 0.05, 0.2, 0.06, 0.13, 0.03, 0.06, 0.12, 0.43, 0.58, 0.13, 0.11, 0.5, 0.49, 0.01, 0.38, 0.46, 0.09, 0.0, 0.7, 0.82, 0.27, 0.31, 0.03, 0.82, 0.14, 0.4, 0.39, 0.24, 0.76, 0.04, 0.31, 0.72, 0.49, 0.0, 0.31, 0.46, 0.07, 0.42, 0.09, 0.52, 0.08, 0.52, 0.5, 0.39, 0.91, 0.92, 0.54, 0.94, 0.58, 0.81, 0.7, 0.73, 0.49, 0.8, 0.15, 0.64, 0.33, 0.0, 0.14, 0.47, 0.03, 0.28, 0.4, 0.14, 0.42, 0.23, 0.01, 0.26, 0.41, 0.0, 0.04, 0.17, 0.4, 0.08, 0.15, 0.16, 0.62, 0.07, 0.01, 0.36, 0.47, 0.06, 0.07, 0.53, 0.67, 0.24, 0.79, 0.19, 0.49, 0.2, 0.73, 0.54, 0.03, 0.11, 0.02, 0.07, 0.1, 0.26, 0.19, 0.06, 0.09, 0.38, 0.21, 0.4, 0.21, 0.44, 0.45, 0.54, 0.48, 0.25, 0.71, 0.81, 0.59, 0.73, 0.69, 0.51, 0.82, 0.55, 0.66, 0.66, 0.34, 0.67, 0.41, 0.26, 0.38, 0.0, 0.77, 0.15, 0.01, 0.52, 0.42, 0.0, 0.39, 0.79, 0.46, 0.4, 0.18, 0.14, 0.05, 0.32, 0.06, 0.0, 0.39, 0.27, 0.0, 0.13, 0.35, 0.34, 0.11, 0.0, 0.28, 0.42, 0.0, 0.0, 0.42, 0.39, 0.07, 0.59, 0.05, 0.46, 0.5, 0.7, 0.06, 0.0, 0.38, 0.14, 0.08, 0.19, 0.28, 0.22, 0.53, 0.12, 0.0, 0.0, 0.01, 0.03, 0.01, 0.0, 0.06, 0.1, 0.14, 0.45, 0.87, 0.4, 0.28, 0.49, 0.38, 0.94, 0.35, 0.12, 0.59, 0.45, 0.06, 0.14, 0.42, 0.06, 0.0, 0.58, 0.09, 0.03, 0.07, 0.48, 0.01, 0.18, 0.38, 0.17, 0.36, 0.81, 0.77, 0.93, 0.55, 0.82, 0.16, 0.05, 0.65, 0.49, 0.01, 0.32, 0.78, 0.43, 0.12, 0.56, 0.78, 0.76, 0.12, 0.21, 0.69, 0.43, 0.0, 0.35, 0.6, 0.05, 0.08, 0.7, 0.75, 0.27, 0.52, 0.14, 0.39, 0.09, 0.05, 0.02, 0.0, 0.0, 0.02, 0.44, 0.0, 0.04, 0.01, 0.33, 0.7, 0.78, 0.91, 0.68, 0.58, 0.21, 0.3, 0.16, 0.02, 0.0, 0.0, 0.0, 0.01, 0.0, 0.06, 0.78, 0.6, 0.93, 0.24, 0.37, 0.08, 0.61, 0.11, 0.02, 0.06, 0.14, 0.03, 0.03, 0.58, 0.01, 0.02, 0.12, 0.51, 0.1, 0.06, 0.74, 0.21, 0.02, 0.04, 0.0, 0.0, 0.0, 0.04, 0.0, 0.11, 0.64, 0.75, 0.32, 0.03, 0.89, 0.64, 0.38, 0.03, 0.66, 0.4, 0.08, 0.03, 0.51, 0.0, 0.15, 0.01, 0.34, 0.67, 0.54, 0.06, 0.04, 0.54, 0.22, 0.0, 0.24, 0.29, 0.0, 0.03, 0.26, 0.25, 0.0, 0.19, 0.22, 0.05, 0.01, 0.48, 0.63, 0.3, 0.67, 0.24, 0.27, 0.89, 0.6, 0.03, 0.24, 0.1, 0.01, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.08, 0.03, 0.6, 0.18, 0.39, 0.61, 0.87, 0.61, 0.84, 0.47, 0.74, 0.15, 0.64, 0.34, 0.2, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.22, 0.19, 0.8, 0.43, 0.37, 0.61, 0.51, 0.1, 0.43, 0.03, 0.0, 0.1, 0.06, 0.66, 0.76, 0.28, 0.01, 0.15, 0.33, 0.71, 0.11, 0.0, 0.44, 0.45, 0.0, 0.12, 0.57, 0.34, 0.0, 0.45, 0.61, 0.1, 0.83, 0.38, 0.04, 0.07, 0.04, 0.03, 0.0, 0.0, 0.0, 0.02, 0.0, 0.24, 0.2, 0.65, 0.25, 0.0, 0.16, 0.14, 0.13, 0.01, 0.03]
RING finger
Component of a SCF(SKP2)-like complex containing CUL1, SKP1, TRIM21 and SKP2.
SCF
null
IRF8, CALR, CUL1, FBXW11, HSPA5, IKBKB, IRF3, SKP1 , VCP,SKP2, DCP2 ,ULK1, BECN1,GABARAP, GABARAPL1, GABARAPL2 , MAP1LC3C,SQSTM1,IRF3 , NMI, IFI35 , CUL1, TRIM21
USP4, IKBKB, TRIM21, CDKN1B, IRF3, IRF8, MNI
mono, 63
null
UBE2D2, UBE2D1, UBE2E1, UBE2E2
Homotrimer
null
90.718042
0.406716
86.651674
0.301227
1,039
P19474
Q02556
17579016, 19494276, BioGrid E3Net
UbiNet, UbiBrowser, 31181401
TRIM21
MASAARLTMMWEEVTCPICLDPFVEPVSIECGHSFCQECISQVGKGGGSVCPVCRQRFLLKNLRPNRQLANMVNNLKEISQEAREGTQGERCAVHGERLHLFCEKDGKALCWVCAQSRKHRDHAMVPLEEAAQEYQEKLQVALGELRRKQELAEKLEVEIAIKRADWKKTVETQKSRIHAEFVQQKNFLVEEEQRQLQELEKDEREQLRILGEKEAKLAQQSQALQELISELDRRCHSSALELLQEVIIVLERSESWNLKDLDITSPELRSVCHVPGLKKMLRTCAVHITLDPDTANPWLILSEDRRQVRLGDTQQSIPGNEERFDSYPMVLGAQHFHSGKHYWEVDVTGKEAWDLGVCRDSVRRKGHFLLSSKSGFWTIWLWNKQKYEAGTYPQTPLHLQVPPCQVGIFLDYEAGMVSFYNITDHGSLIYSFSECAFTGPLRPFFSPGFNDGGKNTAPLTLCPLNIGSQGSTDY
Homo sapiens
Cytoplasm, Cytoplasmic vesicle, autophagosome, Nucleus, Cytoplasm, P-body, Cytoplasm, Stress granule
Low tissue specificity
{'Ciliated cells': '3.8', 'Basal respiratory cells': '6.8', 'Club cells': '5.8', 'Ionocytes': '3.7', 'Mucus glandular cells': '4.8', 'Serous glandular cells': '2.3', 'Gastric mucus-secreting cells': '8.8', 'Proximal enterocytes': '8.9', 'Paneth cells': '3.9', 'Distal enterocytes': '8.5', 'Intestinal goblet cells': '8.4', 'Exocrine glandular cells': '-0.716', 'Basal prostatic cells': '5.4', 'Prostatic glandular cells': '5.0', 'Breast glandular cells': '0.298', 'Breast myoepithelial cells': '0.351', 'Glandular and luminal cells': '5.9', 'Secretory cells': '8.4', 'Basal keratinocytes': '3.2', 'Suprabasal keratinocytes': '2.7', 'Basal squamous epithelial cells': '6.4', 'Squamous epithelial cells': '4.3', 'Alveolar cells type 1': '0.116', 'Alveolar cells type 2': '0.115', 'Salivary duct cells': '3.0', 'Ductal cells': '0.700', 'Hepatocytes': '0.503', 'Cholangiocytes': '11.4', 'Proximal tubular cells': '0.175', 'Distal tubular cells': '0.0', 'Collecting duct cells': '5.8', 'Mesothelial cells': '0.451', 'Sertoli cells': '0.479', 'Granulosa cells': '4.8', 'Enteroendocrine cells': '3.7', 'Pancreatic endocrine cells': '3.4', 'Leydig cells': '0.632', 'Excitatory neurons': '0.2', 'Inhibitory neurons': '0.1', 'Cone photoreceptor cells': '0.0', 'Rod photoreceptor cells': '0.0', 'Bipolar cells': '0.7', 'Horizontal cells': '0.6', 'Astrocytes': '0.0', 'Oligodendrocyte precursor cells': '0.9', 'Oligodendrocytes': '0.1', 'Microglial cells': '1.8', 'Muller glia cells': '2.4', 'Schwann cells': '0.099', 'Spermatogonia': '0.401', 'Spermatocytes': '-0.062', 'Early spermatids': '-0.578', 'Late spermatids': '-0.618', 'Oocytes': '1.5', 'Cytotrophoblasts': '6.6', 'Syncytiotrophoblasts': '9.8', 'Extravillous trophoblasts': '10.0', 'Endothelial cells': '7.8', 'Lymphatic endothelial cells': '6.9', 'Cardiomyocytes': '0.335', 'Skeletal myocytes': '-0.080', 'Smooth muscle cells': '6.3', 'Adipocytes': '8.3', 'Melanocytes': '0.101', 'Fibroblasts': '6.5', 'Peritubular cells': '0.579', 'Endometrial stromal cells': '4.5', 'Ovarian stromal cells': '6.7', 'Undifferentiated cells': '5.9', 'T-cells': '9.9', 'B-cells': '8.8', 'Plasma cells': '5.0', 'Nk-cells': '15.1', 'Granulocytes': '6.2', 'Monocytes': '7.8', 'Macrophages': '8.5', 'Hofbauer cells': '9.9', 'Kupffer cells': '10.3', 'Dendritic cells': '8.0', 'Langerhans cells': '0.466', 'Erythroid cells': '-0.084', 'Adipocytes (Subcutaneous)': '-0.368', 'Adipocytes (Visceral)': '-0.167', 'Breast glandular cells (progenitors)': '0.190', 'Adipocytes (Breast)': '-0.382', 'Colon enterocytes': '0.004', 'Colon enteroendocrine cells': '0.196', 'Enteric glia cells': '-0.129', 'Mitotic cells (Colon)': '0.005', 'Mitotic cells (Heart)': '0.486', 'Podocytes': '-0.114', 'Ascending Loop of Henle cells': '0.371', 'Intercalated cells': '-0.097', 'Cholangiocyte': '0.375', 'NK-cells (Liver)': '-0.278', 'Respiratory ciliated cells': '-0.022', 'Mitotic cells (Lung)': '0.157', 'NK-cells (Lung)': '0.110', 'B-cells (Lung)': '-0.155', 'Alpha cells': '0.333', 'Beta cells': '0.161', 'Prostate glandular cells': '-0.162', 'Prostate basal glandular cells': '0.286', 'Urothelial cells': '0.283', 'Keratinocyte (other)': '0.121', 'Keratinocyte (granular)': '-0.008', 'Hair cortex cells': '-0.113', 'Inner root sheath cells': '-0.069', 'Outer root sheath cells': '0.125', 'Sebaceous gland cells': '0.110', 'Eccrine sweat gland cells': '0.070', 'Adipocytes (Skin)': '0.019', 'Mitotic cells (Skin)': '0.236', 'Parietal cells': '-0.609', 'Chief cells': '-0.599', 'Gastric mucous cells': '-0.193', 'Gastric enteroendocrine cells': '-0.441', 'Mitotic cells (Stomach)': '0.261', 'Parafollicular cells': '-0.028', 'Thyroid glandular cells': '0.094', 'Mitotic cells (Thyroid)': '0.242', 'Adrenal cortex cells': '0.619', 'Adrenal medulla cells': '0.063', 'Mitotic cells (Adrenal gland)': '0.483', 'Minor salivary glandular cells': '0.582', 'Minor salivary gland ductal cells': '0.072', 'Minor salivary gland basal cells': '0.229', 'Mitotic cells (Minor salivary gland)': '0.376', 'Adipocytes (Minor salivary gland)': '0.211', 'Somatotropes': '-0.121', 'Lactotropes': '-0.287', 'Gonadotropes': '0.004', 'Corticotropes': '-0.352', 'Thyrotropes': '-0.054', 'Undifferentiated cells (Pituitary gland)': '0.486', 'Mitotic cells (Spleen)': '-0.016', 'Platelets': '0.115', 'Erythrocytes': '0.098', 'Hematopoietic stem cells': '0.042', 'B-cells (Spleen)': '0.028', 'NK-cells (Spleen)': '0.157', 'Amygdala excitatory': '0.1', 'Cerebellar inhibitory': '0.2', 'Cge interneuron': '0.3', 'Deep-layer corticothalamic and 6b': '0.3', 'Deep-layer intratelencephalic': '0.1', 'Deep-layer near-projecting': '0.1', 'Eccentric medium spiny neuron': '0.4', 'Hippocampal ca1-3': '0.5', 'Hippocampal ca4': '0.1', 'Hippocampal dentate gyrus': '0.3', 'Lamp5-lhx6 and chandelier': '0.3', 'Lower rhombic lip': '0.2', 'Mammillary body': '0.4', 'Medium spiny neuron': '0.6', 'Mge interneuron': '0.1', 'Midbrain-derived inhibitory': '0.6', 'Miscellaneous': '0.6', 'Splatter': '0.5', 'Thalamic excitatory': '1.3', 'Upper rhombic lip': '0.1', 'Upper-layer intratelencephalic': '0.1', 'Astrocyte': '1.5', 'Bergmann glia': '1.5', 'Central nervous system macrophage': '6.0', 'Choroid plexus epithelial cell': '2.9', 'Committed oligodendrocyte precursor': '1.0', 'Ependymal cell': '1.3', 'Oligodendrocyte': '0.1', 'Oligodendrocyte precursor cell': '2.3', 'Endothelial cell': '6.4', 'Pericyte': '5.3', 'Vascular associated smooth muscle cell': '3.1', 'Fibroblast': '5.3', 'Leukocyte': '7.4', 'Basophil': '107.0', 'Eosinophil': '312.5', 'Neutrophil': '496.9', 'Classical monocyte': '25.8', 'Non-classical monocyte': '66.1', 'Intermediate monocyte': '117.0', 'T-reg': '72.1', 'GdT-cell': '89.5', 'MAIT T-cell': '61.2', 'Memory CD4 T-cell': '76.8', 'Naive CD4 T-cell': '47.0', 'Memory CD8 T-cell': '81.1', 'Naive CD8 T-cell': '43.5', 'Memory B-cell': '50.4', 'Naive B-cell': '38.5', 'Plasmacytoid DC': '47.5', 'Myeloid DC': '92.2', 'NK-cell': '88.9', 'Total PBMC': '83.8', 'Vd2 gdTCR': '67.8', 'Memory CD4 T-cell Th1\\/Th17': '48.0', 'Memory CD4 T-cell Th17': '54.6', 'Memory CD4 T-cell Th2': '54.8', 'Non-Vd2 gdTCR': '73.7', 'Memory CD4 T-cell Th1': '58.8', 'Memory CD4 T-cell TFH': '61.9', 'Terminal effector memory CD4 T-cell': '72.8', 'Central memory CD8 T-cell': '59.9', 'Effector memory CD8 T-cell': '90.7', 'Terminal effector memory CD8 T-cell': '75.8', 'Non-switched memory B-cell': '52.6', 'Plasmablast': '62.3', 'Switched memory B-cell': '55.8', 'Exhausted memory B-cell': '52.1', 'Progenitor cell': '44.7', 'Memory T-reg': '82.4', 'Naive CD4 T-cell activated': '133.9', 'Naive CD8 T-cell activated': '163.4', 'Naive T-reg': '54.7'}
2IWG, 5JPX, 5OLM, 6FGA, 6S53, 7BBD, 8A58
{'Adipose Tissue': 21.42795099667774, 'Adrenal Gland': 16.707763565891472, 'Bladder': 21.861904761904764, 'Blood': 61.11958557588805, 'Blood Vessel': 22.62928389513109, 'Brain': 4.305000416351249, 'Breast': 20.001740740740743, 'Cervix Uteri': 26.420526315789473, 'Colon': 23.40817458279846, 'Esophagus': 21.74157577854671, 'Fallopian Tube': 25.39, 'Heart': 6.66628106852497, 'Kidney': 13.61479775280899, 'Liver': 10.388, 'Lung': 32.00464878892734, 'Muscle': 3.944284806973848, 'Nerve': 25.39305008077545, 'Ovary': 30.51811111111111, 'Pancreas': 6.808080182926829, 'Pituitary': 12.995699646643107, 'Prostate': 21.00597551020408, 'Salivary Gland': 16.434148148148147, 'Skin': 17.851811498065228, 'Small Intestine': 28.907085561497325, 'Spleen': 50.16024896265561, 'Stomach': 19.072721448467966, 'Testis': 6.377013850415512, 'Thyroid': 21.553307810107196, 'Uterus': 29.83549295774648, 'Vagina': 21.551141025641027}
IRF8
MCDRNGGRRLRQWLIEQIDSSMYPGLIWENEEKSMFRIPWKHAGKQDYNQEVDASIFKAWAVFKGKFKEGDKAEPATWKTRLRCALNKSPDFEEVTDRSQLDISEPYKVYRIVPEEEQKCKLGVATAGCVNEVTEMECGRSEIDELIKEPSVDDYMGMIKRSPSPPEACRSQLLPDWWAQQPSTGVPLVTGYTTYDAHHSAFSQMVISFYYGGKLVGQATTTCPEGCRLSLSQPGLPGTKLYGPEGLELVRFPPADAIPSERQRQVTRKLFGHLERGVLLHSSRQGVFVKRLCQGRVFCSGNAVVCKGRPNKLERDEVVQVFDTSQFFRELQQFYNSQGRLPDGRVVLCFGEEFPDMAPLRSKLILVQIEQLYVRQLAEEAGKSCGAGSVMQAPEEPPPDQVFRMFPDICASHQRSFFRENQQITV
Homo sapiens
Nucleus, Cytoplasm
Tissue enhanced (lymphoid)
{'Ciliated cells': '3.8', 'Basal respiratory cells': '0.0', 'Club cells': '3.9', 'Ionocytes': '0.0', 'Mucus glandular cells': '5.9', 'Serous glandular cells': '11.0', 'Gastric mucus-secreting cells': '14.7', 'Proximal enterocytes': '32.2', 'Paneth cells': '13.2', 'Distal enterocytes': '14.1', 'Intestinal goblet cells': '9.4', 'Exocrine glandular cells': '-0.393', 'Basal prostatic cells': '18.3', 'Prostatic glandular cells': '1.2', 'Breast glandular cells': '-0.342', 'Breast myoepithelial cells': '-0.383', 'Glandular and luminal cells': '11.1', 'Secretory cells': '13.0', 'Basal keratinocytes': '3.6', 'Suprabasal keratinocytes': '2.0', 'Basal squamous epithelial cells': '0.7', 'Squamous epithelial cells': '0.3', 'Alveolar cells type 1': '-0.051', 'Alveolar cells type 2': '0.335', 'Salivary duct cells': '0.6', 'Ductal cells': '0.414', 'Hepatocytes': '0.192', 'Cholangiocytes': '3.8', 'Proximal tubular cells': '0.245', 'Distal tubular cells': '3.1', 'Collecting duct cells': '0.0', 'Mesothelial cells': '-0.305', 'Sertoli cells': '0.290', 'Granulosa cells': '2.2', 'Enteroendocrine cells': '19.6', 'Pancreatic endocrine cells': '0.0', 'Leydig cells': '0.438', 'Excitatory neurons': '0.5', 'Inhibitory neurons': '0.2', 'Cone photoreceptor cells': '0.0', 'Rod photoreceptor cells': '0.3', 'Bipolar cells': '0.0', 'Horizontal cells': '0.0', 'Astrocytes': '0.0', 'Oligodendrocyte precursor cells': '0.9', 'Oligodendrocytes': '0.4', 'Microglial cells': '32.2', 'Muller glia cells': '2.6', 'Schwann cells': '0.082', 'Spermatogonia': '0.755', 'Spermatocytes': '0.354', 'Early spermatids': '-0.275', 'Late spermatids': '-0.373', 'Oocytes': '9.6', 'Cytotrophoblasts': '0.6', 'Syncytiotrophoblasts': '0.8', 'Extravillous trophoblasts': '6.1', 'Endothelial cells': '5.4', 'Lymphatic endothelial cells': '37.4', 'Cardiomyocytes': '0.355', 'Skeletal myocytes': '-0.031', 'Smooth muscle cells': '6.0', 'Adipocytes': '3.3', 'Melanocytes': '0.108', 'Fibroblasts': '6.3', 'Peritubular cells': '0.291', 'Endometrial stromal cells': '6.6', 'Ovarian stromal cells': '0.9', 'Undifferentiated cells': '26.9', 'T-cells': '17.8', 'B-cells': '339.6', 'Plasma cells': '10.1', 'Nk-cells': '55.9', 'Granulocytes': '1.9', 'Monocytes': '203.4', 'Macrophages': '128.7', 'Hofbauer cells': '86.3', 'Kupffer cells': '90.7', 'Dendritic cells': '1116.2', 'Langerhans cells': '0.376', 'Erythroid cells': '-0.063', 'Adipocytes (Subcutaneous)': '0.544', 'Adipocytes (Visceral)': '0.659', 'Breast glandular cells (progenitors)': '-0.402', 'Adipocytes (Breast)': '0.735', 'Colon enterocytes': '0.346', 'Colon enteroendocrine cells': '0.115', 'Enteric glia cells': '-0.025', 'Mitotic cells (Colon)': '0.550', 'Mitotic cells (Heart)': '0.593', 'Podocytes': '-0.190', 'Ascending Loop of Henle cells': '0.212', 'Intercalated cells': '-0.212', 'Cholangiocyte': '0.287', 'NK-cells (Liver)': '-0.096', 'Respiratory ciliated cells': '-0.084', 'Mitotic cells (Lung)': '0.168', 'NK-cells (Lung)': '-0.130', 'B-cells (Lung)': '0.099', 'Alpha cells': '0.270', 'Beta cells': '0.108', 'Prostate glandular cells': '-0.086', 'Prostate basal glandular cells': '0.226', 'Urothelial cells': '0.178', 'Keratinocyte (other)': '-0.230', 'Keratinocyte (granular)': '-0.049', 'Hair cortex cells': '0.032', 'Inner root sheath cells': '0.064', 'Outer root sheath cells': '0.124', 'Sebaceous gland cells': '0.135', 'Eccrine sweat gland cells': '0.122', 'Adipocytes (Skin)': '0.275', 'Mitotic cells (Skin)': '-0.004', 'Parietal cells': '0.477', 'Chief cells': '0.392', 'Gastric mucous cells': '0.722', 'Gastric enteroendocrine cells': '0.483', 'Mitotic cells (Stomach)': '0.530', 'Parafollicular cells': '-0.028', 'Thyroid glandular cells': '-0.234', 'Mitotic cells (Thyroid)': '0.438', 'Adrenal cortex cells': '0.437', 'Adrenal medulla cells': '0.069', 'Mitotic cells (Adrenal gland)': '0.352', 'Minor salivary glandular cells': '0.459', 'Minor salivary gland ductal cells': '0.090', 'Minor salivary gland basal cells': '0.208', 'Mitotic cells (Minor salivary gland)': '0.433', 'Adipocytes (Minor salivary gland)': '0.261', 'Somatotropes': '-0.375', 'Lactotropes': '-0.391', 'Gonadotropes': '-0.082', 'Corticotropes': '-0.154', 'Thyrotropes': '-0.023', 'Undifferentiated cells (Pituitary gland)': '0.513', 'Mitotic cells (Spleen)': '-0.150', 'Platelets': '0.067', 'Erythrocytes': '-0.313', 'Hematopoietic stem cells': '-0.141', 'B-cells (Spleen)': '0.653', 'NK-cells (Spleen)': '0.213', 'Amygdala excitatory': '0.7', 'Cerebellar inhibitory': '0.2', 'Cge interneuron': '0.3', 'Deep-layer corticothalamic and 6b': '0.2', 'Deep-layer intratelencephalic': '0.2', 'Deep-layer near-projecting': '1.7', 'Eccentric medium spiny neuron': '0.1', 'Hippocampal ca1-3': '2.4', 'Hippocampal ca4': '0.5', 'Hippocampal dentate gyrus': '0.3', 'Lamp5-lhx6 and chandelier': '0.1', 'Lower rhombic lip': '0.2', 'Mammillary body': '0.0', 'Medium spiny neuron': '0.1', 'Mge interneuron': '0.2', 'Midbrain-derived inhibitory': '2.4', 'Miscellaneous': '1.6', 'Splatter': '0.2', 'Thalamic excitatory': '0.1', 'Upper rhombic lip': '3.4', 'Upper-layer intratelencephalic': '0.1', 'Astrocyte': '0.4', 'Bergmann glia': '0.1', 'Central nervous system macrophage': '202.5', 'Choroid plexus epithelial cell': '0.1', 'Committed oligodendrocyte precursor': '1.5', 'Ependymal cell': '0.6', 'Oligodendrocyte': '0.3', 'Oligodendrocyte precursor cell': '0.4', 'Endothelial cell': '0.4', 'Pericyte': '0.2', 'Vascular associated smooth muscle cell': '2.6', 'Fibroblast': '1.0', 'Leukocyte': '18.2', 'Basophil': '2.0', 'Eosinophil': '2.6', 'Neutrophil': '7.3', 'Classical monocyte': '215.7', 'Non-classical monocyte': '118.4', 'Intermediate monocyte': '353.1', 'T-reg': '4.0', 'GdT-cell': '3.1', 'MAIT T-cell': '8.7', 'Memory CD4 T-cell': '1.4', 'Naive CD4 T-cell': '7.1', 'Memory CD8 T-cell': '2.0', 'Naive CD8 T-cell': '5.7', 'Memory B-cell': '335.7', 'Naive B-cell': '693.5', 'Plasmacytoid DC': '9554.1', 'Myeloid DC': '651.6', 'NK-cell': '64.4', 'Total PBMC': '255.7', 'Vd2 gdTCR': '5.6', 'Memory CD4 T-cell Th1\\/Th17': '0.8', 'Memory CD4 T-cell Th17': '0.4', 'Memory CD4 T-cell Th2': '0.6', 'Non-Vd2 gdTCR': '23.9', 'Memory CD4 T-cell Th1': '2.2', 'Memory CD4 T-cell TFH': '3.0', 'Terminal effector memory CD4 T-cell': '1.0', 'Central memory CD8 T-cell': '2.6', 'Effector memory CD8 T-cell': '4.7', 'Terminal effector memory CD8 T-cell': '4.2', 'Non-switched memory B-cell': '765.6', 'Plasmablast': '29.8', 'Switched memory B-cell': '709.3', 'Exhausted memory B-cell': '739.0', 'Progenitor cell': '88.0', 'Memory T-reg': '2.1', 'Naive CD4 T-cell activated': '477.5', 'Naive CD8 T-cell activated': '450.2', 'Naive T-reg': '3.7'}
null
{'Adipose Tissue': 16.257548172757474, 'Adrenal Gland': 4.297138759689923, 'Bladder': 4.184238095238095, 'Blood': 44.14191356297094, 'Blood Vessel': 4.490638127340824, 'Brain': 2.1415881415594247, 'Breast': 10.688692810457516, 'Cervix Uteri': 3.313642105263158, 'Colon': 8.604082028241335, 'Esophagus': 2.588061384083045, 'Fallopian Tube': 3.846455555555555, 'Heart': 1.2129353426248548, 'Kidney': 4.887050561797753, 'Liver': 6.882469026548673, 'Lung': 22.55698269896194, 'Muscle': 0.3273073312577833, 'Nerve': 7.172050080775444, 'Ovary': 1.9739965, 'Pancreas': 1.4692594512195123, 'Pituitary': 2.388328268551237, 'Prostate': 4.583542040816326, 'Salivary Gland': 3.5091185185185187, 'Skin': 1.97340962631288, 'Small Intestine': 66.68702139037433, 'Spleen': 108.56041493775936, 'Stomach': 7.915849860724235, 'Testis': 3.1441551246537394, 'Thyroid': 5.906545788667688, 'Uterus': 2.494560563380282, 'Vagina': 2.1719192307692308}
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RING finger
Component of a SCF(SKP2)-like complex containing CUL1, SKP1, TRIM21 and SKP2.
SCF
null
IRF8, CALR, CUL1, FBXW11, HSPA5, IKBKB, IRF3, SKP1 , VCP,SKP2, DCP2 ,ULK1, BECN1,GABARAP, GABARAPL1, GABARAPL2 , MAP1LC3C,SQSTM1,IRF3 , NMI, IFI35 , CUL1, TRIM21
USP4, IKBKB, TRIM21, CDKN1B, IRF3, IRF8, MNI
mono, 63
null
UBE2D2, UBE2D1, UBE2E1, UBE2E2
Homotrimer
null
90.718042
0.406716
74.384413
0.477042
1,865
P19474
Q04206
32232831
UbiNet, UbiBrowser
TRIM21
MASAARLTMMWEEVTCPICLDPFVEPVSIECGHSFCQECISQVGKGGGSVCPVCRQRFLLKNLRPNRQLANMVNNLKEISQEAREGTQGERCAVHGERLHLFCEKDGKALCWVCAQSRKHRDHAMVPLEEAAQEYQEKLQVALGELRRKQELAEKLEVEIAIKRADWKKTVETQKSRIHAEFVQQKNFLVEEEQRQLQELEKDEREQLRILGEKEAKLAQQSQALQELISELDRRCHSSALELLQEVIIVLERSESWNLKDLDITSPELRSVCHVPGLKKMLRTCAVHITLDPDTANPWLILSEDRRQVRLGDTQQSIPGNEERFDSYPMVLGAQHFHSGKHYWEVDVTGKEAWDLGVCRDSVRRKGHFLLSSKSGFWTIWLWNKQKYEAGTYPQTPLHLQVPPCQVGIFLDYEAGMVSFYNITDHGSLIYSFSECAFTGPLRPFFSPGFNDGGKNTAPLTLCPLNIGSQGSTDY
Homo sapiens
Cytoplasm, Cytoplasmic vesicle, autophagosome, Nucleus, Cytoplasm, P-body, Cytoplasm, Stress granule
Low tissue specificity
{'Ciliated cells': '3.8', 'Basal respiratory cells': '6.8', 'Club cells': '5.8', 'Ionocytes': '3.7', 'Mucus glandular cells': '4.8', 'Serous glandular cells': '2.3', 'Gastric mucus-secreting cells': '8.8', 'Proximal enterocytes': '8.9', 'Paneth cells': '3.9', 'Distal enterocytes': '8.5', 'Intestinal goblet cells': '8.4', 'Exocrine glandular cells': '-0.716', 'Basal prostatic cells': '5.4', 'Prostatic glandular cells': '5.0', 'Breast glandular cells': '0.298', 'Breast myoepithelial cells': '0.351', 'Glandular and luminal cells': '5.9', 'Secretory cells': '8.4', 'Basal keratinocytes': '3.2', 'Suprabasal keratinocytes': '2.7', 'Basal squamous epithelial cells': '6.4', 'Squamous epithelial cells': '4.3', 'Alveolar cells type 1': '0.116', 'Alveolar cells type 2': '0.115', 'Salivary duct cells': '3.0', 'Ductal cells': '0.700', 'Hepatocytes': '0.503', 'Cholangiocytes': '11.4', 'Proximal tubular cells': '0.175', 'Distal tubular cells': '0.0', 'Collecting duct cells': '5.8', 'Mesothelial cells': '0.451', 'Sertoli cells': '0.479', 'Granulosa cells': '4.8', 'Enteroendocrine cells': '3.7', 'Pancreatic endocrine cells': '3.4', 'Leydig cells': '0.632', 'Excitatory neurons': '0.2', 'Inhibitory neurons': '0.1', 'Cone photoreceptor cells': '0.0', 'Rod photoreceptor cells': '0.0', 'Bipolar cells': '0.7', 'Horizontal cells': '0.6', 'Astrocytes': '0.0', 'Oligodendrocyte precursor cells': '0.9', 'Oligodendrocytes': '0.1', 'Microglial cells': '1.8', 'Muller glia cells': '2.4', 'Schwann cells': '0.099', 'Spermatogonia': '0.401', 'Spermatocytes': '-0.062', 'Early spermatids': '-0.578', 'Late spermatids': '-0.618', 'Oocytes': '1.5', 'Cytotrophoblasts': '6.6', 'Syncytiotrophoblasts': '9.8', 'Extravillous trophoblasts': '10.0', 'Endothelial cells': '7.8', 'Lymphatic endothelial cells': '6.9', 'Cardiomyocytes': '0.335', 'Skeletal myocytes': '-0.080', 'Smooth muscle cells': '6.3', 'Adipocytes': '8.3', 'Melanocytes': '0.101', 'Fibroblasts': '6.5', 'Peritubular cells': '0.579', 'Endometrial stromal cells': '4.5', 'Ovarian stromal cells': '6.7', 'Undifferentiated cells': '5.9', 'T-cells': '9.9', 'B-cells': '8.8', 'Plasma cells': '5.0', 'Nk-cells': '15.1', 'Granulocytes': '6.2', 'Monocytes': '7.8', 'Macrophages': '8.5', 'Hofbauer cells': '9.9', 'Kupffer cells': '10.3', 'Dendritic cells': '8.0', 'Langerhans cells': '0.466', 'Erythroid cells': '-0.084', 'Adipocytes (Subcutaneous)': '-0.368', 'Adipocytes (Visceral)': '-0.167', 'Breast glandular cells (progenitors)': '0.190', 'Adipocytes (Breast)': '-0.382', 'Colon enterocytes': '0.004', 'Colon enteroendocrine cells': '0.196', 'Enteric glia cells': '-0.129', 'Mitotic cells (Colon)': '0.005', 'Mitotic cells (Heart)': '0.486', 'Podocytes': '-0.114', 'Ascending Loop of Henle cells': '0.371', 'Intercalated cells': '-0.097', 'Cholangiocyte': '0.375', 'NK-cells (Liver)': '-0.278', 'Respiratory ciliated cells': '-0.022', 'Mitotic cells (Lung)': '0.157', 'NK-cells (Lung)': '0.110', 'B-cells (Lung)': '-0.155', 'Alpha cells': '0.333', 'Beta cells': '0.161', 'Prostate glandular cells': '-0.162', 'Prostate basal glandular cells': '0.286', 'Urothelial cells': '0.283', 'Keratinocyte (other)': '0.121', 'Keratinocyte (granular)': '-0.008', 'Hair cortex cells': '-0.113', 'Inner root sheath cells': '-0.069', 'Outer root sheath cells': '0.125', 'Sebaceous gland cells': '0.110', 'Eccrine sweat gland cells': '0.070', 'Adipocytes (Skin)': '0.019', 'Mitotic cells (Skin)': '0.236', 'Parietal cells': '-0.609', 'Chief cells': '-0.599', 'Gastric mucous cells': '-0.193', 'Gastric enteroendocrine cells': '-0.441', 'Mitotic cells (Stomach)': '0.261', 'Parafollicular cells': '-0.028', 'Thyroid glandular cells': '0.094', 'Mitotic cells (Thyroid)': '0.242', 'Adrenal cortex cells': '0.619', 'Adrenal medulla cells': '0.063', 'Mitotic cells (Adrenal gland)': '0.483', 'Minor salivary glandular cells': '0.582', 'Minor salivary gland ductal cells': '0.072', 'Minor salivary gland basal cells': '0.229', 'Mitotic cells (Minor salivary gland)': '0.376', 'Adipocytes (Minor salivary gland)': '0.211', 'Somatotropes': '-0.121', 'Lactotropes': '-0.287', 'Gonadotropes': '0.004', 'Corticotropes': '-0.352', 'Thyrotropes': '-0.054', 'Undifferentiated cells (Pituitary gland)': '0.486', 'Mitotic cells (Spleen)': '-0.016', 'Platelets': '0.115', 'Erythrocytes': '0.098', 'Hematopoietic stem cells': '0.042', 'B-cells (Spleen)': '0.028', 'NK-cells (Spleen)': '0.157', 'Amygdala excitatory': '0.1', 'Cerebellar inhibitory': '0.2', 'Cge interneuron': '0.3', 'Deep-layer corticothalamic and 6b': '0.3', 'Deep-layer intratelencephalic': '0.1', 'Deep-layer near-projecting': '0.1', 'Eccentric medium spiny neuron': '0.4', 'Hippocampal ca1-3': '0.5', 'Hippocampal ca4': '0.1', 'Hippocampal dentate gyrus': '0.3', 'Lamp5-lhx6 and chandelier': '0.3', 'Lower rhombic lip': '0.2', 'Mammillary body': '0.4', 'Medium spiny neuron': '0.6', 'Mge interneuron': '0.1', 'Midbrain-derived inhibitory': '0.6', 'Miscellaneous': '0.6', 'Splatter': '0.5', 'Thalamic excitatory': '1.3', 'Upper rhombic lip': '0.1', 'Upper-layer intratelencephalic': '0.1', 'Astrocyte': '1.5', 'Bergmann glia': '1.5', 'Central nervous system macrophage': '6.0', 'Choroid plexus epithelial cell': '2.9', 'Committed oligodendrocyte precursor': '1.0', 'Ependymal cell': '1.3', 'Oligodendrocyte': '0.1', 'Oligodendrocyte precursor cell': '2.3', 'Endothelial cell': '6.4', 'Pericyte': '5.3', 'Vascular associated smooth muscle cell': '3.1', 'Fibroblast': '5.3', 'Leukocyte': '7.4', 'Basophil': '107.0', 'Eosinophil': '312.5', 'Neutrophil': '496.9', 'Classical monocyte': '25.8', 'Non-classical monocyte': '66.1', 'Intermediate monocyte': '117.0', 'T-reg': '72.1', 'GdT-cell': '89.5', 'MAIT T-cell': '61.2', 'Memory CD4 T-cell': '76.8', 'Naive CD4 T-cell': '47.0', 'Memory CD8 T-cell': '81.1', 'Naive CD8 T-cell': '43.5', 'Memory B-cell': '50.4', 'Naive B-cell': '38.5', 'Plasmacytoid DC': '47.5', 'Myeloid DC': '92.2', 'NK-cell': '88.9', 'Total PBMC': '83.8', 'Vd2 gdTCR': '67.8', 'Memory CD4 T-cell Th1\\/Th17': '48.0', 'Memory CD4 T-cell Th17': '54.6', 'Memory CD4 T-cell Th2': '54.8', 'Non-Vd2 gdTCR': '73.7', 'Memory CD4 T-cell Th1': '58.8', 'Memory CD4 T-cell TFH': '61.9', 'Terminal effector memory CD4 T-cell': '72.8', 'Central memory CD8 T-cell': '59.9', 'Effector memory CD8 T-cell': '90.7', 'Terminal effector memory CD8 T-cell': '75.8', 'Non-switched memory B-cell': '52.6', 'Plasmablast': '62.3', 'Switched memory B-cell': '55.8', 'Exhausted memory B-cell': '52.1', 'Progenitor cell': '44.7', 'Memory T-reg': '82.4', 'Naive CD4 T-cell activated': '133.9', 'Naive CD8 T-cell activated': '163.4', 'Naive T-reg': '54.7'}
2IWG, 5JPX, 5OLM, 6FGA, 6S53, 7BBD, 8A58
{'Adipose Tissue': 21.42795099667774, 'Adrenal Gland': 16.707763565891472, 'Bladder': 21.861904761904764, 'Blood': 61.11958557588805, 'Blood Vessel': 22.62928389513109, 'Brain': 4.305000416351249, 'Breast': 20.001740740740743, 'Cervix Uteri': 26.420526315789473, 'Colon': 23.40817458279846, 'Esophagus': 21.74157577854671, 'Fallopian Tube': 25.39, 'Heart': 6.66628106852497, 'Kidney': 13.61479775280899, 'Liver': 10.388, 'Lung': 32.00464878892734, 'Muscle': 3.944284806973848, 'Nerve': 25.39305008077545, 'Ovary': 30.51811111111111, 'Pancreas': 6.808080182926829, 'Pituitary': 12.995699646643107, 'Prostate': 21.00597551020408, 'Salivary Gland': 16.434148148148147, 'Skin': 17.851811498065228, 'Small Intestine': 28.907085561497325, 'Spleen': 50.16024896265561, 'Stomach': 19.072721448467966, 'Testis': 6.377013850415512, 'Thyroid': 21.553307810107196, 'Uterus': 29.83549295774648, 'Vagina': 21.551141025641027}
RELA
MDELFPLIFPAEPAQASGPYVEIIEQPKQRGMRFRYKCEGRSAGSIPGERSTDTTKTHPTIKINGYTGPGTVRISLVTKDPPHRPHPHELVGKDCRDGFYEAELCPDRCIHSFQNLGIQCVKKRDLEQAISQRIQTNNNPFQVPIEEQRGDYDLNAVRLCFQVTVRDPSGRPLRLPPVLSHPIFDNRAPNTAELKICRVNRNSGSCLGGDEIFLLCDKVQKEDIEVYFTGPGWEARGSFSQADVHRQVAIVFRTPPYADPSLQAPVRVSMQLRRPSDRELSEPMEFQYLPDTDDRHRIEEKRKRTYETFKSIMKKSPFSGPTDPRPPPRRIAVPSRSSASVPKPAPQPYPFTSSLSTINYDEFPTMVFPSGQISQASALAPAPPQVLPQAPAPAPAPAMVSALAQAPAPVPVLAPGPPQAVAPPAPKPTQAGEGTLSEALLQLQFDDEDLGALLGNSTDPAVFTDLASVDNSEFQQLLNQGIPVAPHTTEPMLMEYPEAITRLVTGAQRPPDPAPAPLGAPGLPNGLLSGDEDFSSIADMDFSALLSQISS
Homo sapiens
Nucleus, Cytoplasm
Low tissue specificity
{'Ciliated cells': '27.8', 'Basal respiratory cells': '36.3', 'Club cells': '30.6', 'Ionocytes': '35.0', 'Mucus glandular cells': '30.0', 'Serous glandular cells': '18.6', 'Gastric mucus-secreting cells': '27.7', 'Proximal enterocytes': '21.6', 'Paneth cells': '22.1', 'Distal enterocytes': '25.2', 'Intestinal goblet cells': '28.0', 'Exocrine glandular cells': '-0.781', 'Basal prostatic cells': '32.0', 'Prostatic glandular cells': '21.8', 'Breast glandular cells': '0.480', 'Breast myoepithelial cells': '0.511', 'Glandular and luminal cells': '48.1', 'Secretory cells': '56.4', 'Basal keratinocytes': '41.7', 'Suprabasal keratinocytes': '42.7', 'Basal squamous epithelial cells': '27.5', 'Squamous epithelial cells': '28.7', 'Alveolar cells type 1': '0.274', 'Alveolar cells type 2': '-0.452', 'Salivary duct cells': '26.7', 'Ductal cells': '0.612', 'Hepatocytes': '0.191', 'Cholangiocytes': '15.3', 'Proximal tubular cells': '0.114', 'Distal tubular cells': '27.7', 'Collecting duct cells': '13.6', 'Mesothelial cells': '0.281', 'Sertoli cells': '0.582', 'Granulosa cells': '26.4', 'Enteroendocrine cells': '19.9', 'Pancreatic endocrine cells': '34.0', 'Leydig cells': '0.608', 'Excitatory neurons': '5.3', 'Inhibitory neurons': '5.7', 'Cone photoreceptor cells': '3.4', 'Rod photoreceptor cells': '8.0', 'Bipolar cells': '7.7', 'Horizontal cells': '7.6', 'Astrocytes': '8.7', 'Oligodendrocyte precursor cells': '7.1', 'Oligodendrocytes': '12.8', 'Microglial cells': '9.8', 'Muller glia cells': '16.3', 'Schwann cells': '0.049', 'Spermatogonia': '0.500', 'Spermatocytes': '0.061', 'Early spermatids': '-0.521', 'Late spermatids': '-0.641', 'Oocytes': '19.9', 'Cytotrophoblasts': '23.0', 'Syncytiotrophoblasts': '47.7', 'Extravillous trophoblasts': '27.7', 'Endothelial cells': '45.2', 'Lymphatic endothelial cells': '33.2', 'Cardiomyocytes': '0.352', 'Skeletal myocytes': '-0.285', 'Smooth muscle cells': '35.1', 'Adipocytes': '41.0', 'Melanocytes': '0.007', 'Fibroblasts': '29.1', 'Peritubular cells': '0.494', 'Endometrial stromal cells': '24.8', 'Ovarian stromal cells': '26.5', 'Undifferentiated cells': '22.1', 'T-cells': '38.6', 'B-cells': '31.6', 'Plasma cells': '31.3', 'Nk-cells': '37.6', 'Granulocytes': '50.3', 'Monocytes': '61.6', 'Macrophages': '31.1', 'Hofbauer cells': '29.0', 'Kupffer cells': '32.0', 'Dendritic cells': '33.9', 'Langerhans cells': '0.058', 'Erythroid cells': '0.030', 'Adipocytes (Subcutaneous)': '-0.433', 'Adipocytes (Visceral)': '-0.372', 'Breast glandular cells (progenitors)': '0.381', 'Adipocytes (Breast)': '-0.610', 'Colon enterocytes': '-0.207', 'Colon enteroendocrine cells': '0.122', 'Enteric glia cells': '-0.070', 'Mitotic cells (Colon)': '-0.100', 'Mitotic cells (Heart)': '0.438', 'Podocytes': '-0.076', 'Ascending Loop of Henle cells': '0.300', 'Intercalated cells': '-0.112', 'Cholangiocyte': '0.350', 'NK-cells (Liver)': '-0.205', 'Respiratory ciliated cells': '0.037', 'Mitotic cells (Lung)': '-0.355', 'NK-cells (Lung)': '0.499', 'B-cells (Lung)': '0.230', 'Alpha cells': '0.329', 'Beta cells': '0.166', 'Prostate glandular cells': '-0.250', 'Prostate basal glandular cells': '0.085', 'Urothelial cells': '0.227', 'Keratinocyte (other)': '0.166', 'Keratinocyte (granular)': '0.146', 'Hair cortex cells': '-0.085', 'Inner root sheath cells': '-0.061', 'Outer root sheath cells': '-0.109', 'Sebaceous gland cells': '-0.251', 'Eccrine sweat gland cells': '-0.128', 'Adipocytes (Skin)': '-0.097', 'Mitotic cells (Skin)': '-0.171', 'Parietal cells': '-0.714', 'Chief cells': '-0.564', 'Gastric mucous cells': '-0.402', 'Gastric enteroendocrine cells': '-0.424', 'Mitotic cells (Stomach)': '-0.035', 'Parafollicular cells': '0.023', 'Thyroid glandular cells': '-0.011', 'Mitotic cells (Thyroid)': '0.012', 'Adrenal cortex cells': '0.387', 'Adrenal medulla cells': '0.016', 'Mitotic cells (Adrenal gland)': '0.000', 'Minor salivary glandular cells': '0.624', 'Minor salivary gland ductal cells': '-0.001', 'Minor salivary gland basal cells': '0.331', 'Mitotic cells (Minor salivary gland)': '0.331', 'Adipocytes (Minor salivary gland)': '0.169', 'Somatotropes': '-0.129', 'Lactotropes': '-0.275', 'Gonadotropes': '-0.181', 'Corticotropes': '-0.141', 'Thyrotropes': '-0.144', 'Undifferentiated cells (Pituitary gland)': '0.182', 'Mitotic cells (Spleen)': '-0.422', 'Platelets': '-0.263', 'Erythrocytes': '-0.165', 'Hematopoietic stem cells': '-0.378', 'B-cells (Spleen)': '0.415', 'NK-cells (Spleen)': '0.328', 'Amygdala excitatory': '5.4', 'Cerebellar inhibitory': '6.9', 'Cge interneuron': '7.3', 'Deep-layer corticothalamic and 6b': '7.3', 'Deep-layer intratelencephalic': '6.5', 'Deep-layer near-projecting': '7.0', 'Eccentric medium spiny neuron': '6.0', 'Hippocampal ca1-3': '7.3', 'Hippocampal ca4': '4.9', 'Hippocampal dentate gyrus': '3.8', 'Lamp5-lhx6 and chandelier': '7.7', 'Lower rhombic lip': '6.6', 'Mammillary body': '5.7', 'Medium spiny neuron': '5.3', 'Mge interneuron': '7.2', 'Midbrain-derived inhibitory': '5.8', 'Miscellaneous': '8.0', 'Splatter': '6.4', 'Thalamic excitatory': '8.1', 'Upper rhombic lip': '7.2', 'Upper-layer intratelencephalic': '6.5', 'Astrocyte': '14.1', 'Bergmann glia': '9.6', 'Central nervous system macrophage': '14.7', 'Choroid plexus epithelial cell': '5.8', 'Committed oligodendrocyte precursor': '9.6', 'Ependymal cell': '9.3', 'Oligodendrocyte': '15.2', 'Oligodendrocyte precursor cell': '11.0', 'Endothelial cell': '28.3', 'Pericyte': '22.8', 'Vascular associated smooth muscle cell': '22.6', 'Fibroblast': '12.8', 'Leukocyte': '22.3', 'Basophil': '122.8', 'Eosinophil': '18.5', 'Neutrophil': '147.1', 'Classical monocyte': '72.4', 'Non-classical monocyte': '55.5', 'Intermediate monocyte': '87.1', 'T-reg': '97.8', 'GdT-cell': '22.7', 'MAIT T-cell': '129.9', 'Memory CD4 T-cell': '19.8', 'Naive CD4 T-cell': '84.3', 'Memory CD8 T-cell': '22.4', 'Naive CD8 T-cell': '90.3', 'Memory B-cell': '17.2', 'Naive B-cell': '76.6', 'Plasmacytoid DC': '113.0', 'Myeloid DC': '94.9', 'NK-cell': '121.3', 'Total PBMC': '88.7', 'Vd2 gdTCR': '112.1', 'Memory CD4 T-cell Th1\\/Th17': '117.2', 'Memory CD4 T-cell Th17': '127.2', 'Memory CD4 T-cell Th2': '135.9', 'Non-Vd2 gdTCR': '129.1', 'Memory CD4 T-cell Th1': '143.4', 'Memory CD4 T-cell TFH': '151.5', 'Terminal effector memory CD4 T-cell': '115.2', 'Central memory CD8 T-cell': '117.5', 'Effector memory CD8 T-cell': '117.7', 'Terminal effector memory CD8 T-cell': '130.2', 'Non-switched memory B-cell': '100.9', 'Plasmablast': '80.7', 'Switched memory B-cell': '92.2', 'Exhausted memory B-cell': '84.4', 'Progenitor cell': '66.9', 'Memory T-reg': '133.5', 'Naive CD4 T-cell activated': '127.6', 'Naive CD8 T-cell activated': '142.7', 'Naive T-reg': '94.6'}
1NFI, 2LSP, 2O61, 3GUT, 3QXY, 3RC0, 4KV1, 4KV4, 5U4K, 5URN, 6NV2, 6QHL, 6QHM, 6YOW, 6YOX, 6YOY, 6YP2, 6YP3, 6YP8, 6YPL, 6YPY, 6YQ2, 7BI3, 7BIQ, 7BIW, 7BIY, 7BJB, 7BJF, 7BJL, 7BJW, 7BKH, 7LET, 7LEU, 7LF4, 7NJ9, 7NJB, 7NK3, 7NK5, 7NLA, 7NLE, 7NM1, 7NM3, 7NM9, 7NMH, 7NQP, 7NR7, 7NSV, 7NV4, 7NVI, 7NWS, 7NXS, 7NXT, 7NXW, 7NXY, 7NY4, 7NYE, 7NYF, 7NYG, 7NZ6, 7NZG, 7NZK, 7NZV, 7O34, 7O3A, 7O3F, 7O3P, 7O3Q, 7O3R, 7O3S, 7O57, 7O59, 7O5A, 7O5C, 7O5D, 7O5F, 7O5G, 7O5O, 7O5P, 7O5S, 7O5U, 7O5X, 7O6F, 7O6G, 7O6I, 7O6J, 7O6K, 7O6M, 7O6O
{'Adipose Tissue': 82.80447674418605, 'Adrenal Gland': 42.26968992248062, 'Bladder': 84.57047619047619, 'Blood': 59.54979547900969, 'Blood Vessel': 109.75376029962544, 'Brain': 22.916971233913703, 'Breast': 84.56089324618736, 'Cervix Uteri': 103.45368421052632, 'Colon': 69.09243902439025, 'Esophagus': 74.06722491349481, 'Fallopian Tube': 104.69555555555556, 'Heart': 26.793315911730545, 'Kidney': 40.134494382022474, 'Liver': 32.119986725663715, 'Lung': 106.7089446366782, 'Muscle': 41.67884184308842, 'Nerve': 102.27177705977384, 'Ovary': 102.65655555555556, 'Pancreas': 24.647435975609756, 'Pituitary': 47.66272084805654, 'Prostate': 82.42983673469388, 'Salivary Gland': 61.727777777777774, 'Skin': 73.85459922609176, 'Small Intestine': 61.1064705882353, 'Spleen': 77.23058091286308, 'Stomach': 56.823732590529254, 'Testis': 40.39961218836565, 'Thyroid': 75.54470137825422, 'Uterus': 111.27478873239436, 'Vagina': 89.5852564102564}
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[0.99, 1.0, 0.81, 0.93, 0.81, 0.78, 0.76, 0.89, 0.78, 0.92, 0.9, 0.84, 0.88, 0.89, 0.83, 0.55, 0.94, 0.54, 0.23, 0.45, 0.1, 0.46, 0.16, 0.33, 0.07, 0.16, 0.01, 0.34, 0.33, 0.11, 0.43, 0.1, 0.6, 0.02, 0.17, 0.29, 0.73, 0.7, 0.38, 0.83, 0.83, 0.85, 0.13, 0.5, 0.42, 0.02, 0.29, 0.0, 0.43, 0.61, 0.19, 0.54, 0.93, 0.91, 0.63, 0.77, 0.25, 0.2, 0.01, 0.11, 0.0, 0.33, 0.05, 0.11, 0.82, 0.18, 0.65, 0.18, 0.39, 0.17, 0.37, 0.03, 0.19, 0.0, 0.0, 0.03, 0.0, 0.1, 0.35, 0.74, 0.82, 0.4, 0.18, 0.15, 0.01, 0.0, 0.01, 0.02, 0.23, 0.02, 0.25, 0.54, 0.73, 0.49, 0.24, 0.61, 0.42, 0.06, 0.05, 0.12, 0.33, 0.2, 0.87, 0.06, 0.44, 0.47, 0.89, 0.68, 0.27, 0.58, 0.12, 0.48, 0.04, 0.61, 0.53, 0.01, 0.02, 0.0, 0.2, 0.1, 0.17, 0.37, 0.79, 0.85, 0.4, 0.2, 0.75, 0.72, 0.08, 0.07, 0.5, 0.4, 0.02, 0.31, 0.84, 0.3, 0.74, 0.01, 0.15, 0.11, 0.4, 0.8, 0.11, 0.52, 0.49, 0.8, 0.47, 0.05, 0.73, 0.51, 0.87, 0.11, 0.42, 0.23, 0.26, 0.01, 0.0, 0.24, 0.0, 0.0, 0.01, 0.25, 0.01, 0.25, 0.02, 0.58, 0.31, 1.0, 0.66, 0.53, 0.73, 0.78, 0.37, 0.85, 0.08, 0.75, 0.34, 0.23, 0.27, 0.01, 0.41, 0.13, 0.0, 0.1, 0.09, 0.35, 0.68, 0.11, 0.22, 0.37, 0.1, 0.09, 0.48, 0.06, 0.57, 0.11, 0.48, 0.76, 0.26, 0.6, 0.48, 0.62, 0.3, 0.08, 0.22, 0.0, 0.5, 0.28, 0.5, 0.19, 0.48, 0.0, 0.48, 0.0, 0.47, 0.08, 0.49, 0.58, 0.01, 0.28, 0.47, 0.72, 0.18, 0.08, 0.14, 0.0, 0.15, 0.0, 0.28, 0.35, 0.8, 0.96, 0.15, 0.73, 0.16, 0.58, 0.1, 0.55, 0.29, 0.55, 0.52, 0.85, 0.35, 0.09, 0.66, 0.9, 0.37, 0.4, 0.18, 0.0, 0.23, 0.02, 0.57, 0.03, 0.09, 0.64, 0.16, 0.61, 0.4, 0.56, 0.63, 0.1, 0.87, 0.65, 0.56, 0.25, 0.66, 0.04, 0.32, 0.01, 0.11, 0.0, 0.2, 0.0, 0.39, 0.68, 0.44, 0.74, 0.28, 0.49, 0.06, 0.9, 0.62, 0.31, 0.47, 0.0, 0.37, 0.0, 0.36, 0.27, 0.41, 0.53, 0.49, 0.59, 0.8, 0.59, 0.58, 0.62, 0.46, 0.64, 0.65, 0.66, 0.68, 0.88, 0.4, 0.6, 0.7, 0.54, 0.56, 0.4, 0.4, 0.55, 0.53, 0.73, 0.79, 0.6, 0.7, 0.89, 0.83, 0.58, 0.88, 0.91, 0.6, 0.94, 0.78, 0.92, 0.89, 0.85, 0.9, 0.92, 0.77, 0.85, 0.76, 0.89, 0.82, 0.9, 0.83, 0.82, 0.76, 0.88, 0.85, 0.86, 0.93, 0.91, 0.84, 0.88, 0.73, 0.88, 0.77, 0.86, 0.88, 0.88, 0.92, 0.95, 0.91, 0.94, 0.84, 0.86, 0.71, 0.91, 0.76, 0.96, 0.94, 0.94, 0.91, 0.87, 0.88, 0.9, 0.95, 0.98, 0.99, 0.97, 1.0, 0.98, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 0.95, 1.0, 0.96, 1.0, 1.0, 0.97, 1.0, 0.95, 0.99, 0.97, 0.97, 1.0, 0.99, 0.96, 1.0, 0.96, 0.99, 0.95, 0.97, 0.89, 0.94, 0.98, 0.96, 1.0, 1.0, 0.98, 0.96, 0.98, 0.97, 1.0, 0.95, 1.0, 0.9, 0.97, 1.0, 0.97, 1.0, 0.95, 0.99, 0.93, 0.96, 0.99, 0.98, 0.97, 0.96, 1.0, 0.97, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 0.99, 1.0, 0.96, 1.0, 0.93, 0.92, 0.75, 0.74, 0.82, 0.73, 0.96, 0.94, 0.82, 0.98, 0.9, 0.82, 0.96, 0.97, 0.96, 0.98, 0.97, 1.0, 0.92, 1.0, 0.92, 0.9, 0.97, 0.83, 0.63, 0.83, 0.77, 0.75, 0.65, 0.74, 0.52, 0.41, 0.74, 0.63, 0.61, 0.6, 0.71, 0.69, 0.81, 0.74, 0.77, 0.84, 0.9, 0.86, 0.72, 0.99, 0.89, 0.98, 1.0, 0.93, 0.94, 0.95, 0.89, 0.86, 0.91, 0.66, 0.7, 0.62, 0.7, 0.44, 0.46, 0.64, 0.85, 0.81, 0.64, 0.69, 0.72, 0.93, 0.95, 0.9, 0.94, 0.92, 0.95, 0.95, 0.97, 0.98, 1.0, 0.97, 1.0, 0.96, 0.98, 1.0, 0.98, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 0.92, 1.0, 0.91, 0.99, 1.0, 1.0, 0.95, 0.99, 0.91, 0.85, 0.92, 0.85, 0.73, 0.9, 0.96, 0.78, 0.85, 0.93, 0.91, 0.85]
RING finger
Component of a SCF(SKP2)-like complex containing CUL1, SKP1, TRIM21 and SKP2.
SCF
null
IRF8, CALR, CUL1, FBXW11, HSPA5, IKBKB, IRF3, SKP1 , VCP,SKP2, DCP2 ,ULK1, BECN1,GABARAP, GABARAPL1, GABARAPL2 , MAP1LC3C,SQSTM1,IRF3 , NMI, IFI35 , CUL1, TRIM21
USP4, IKBKB, TRIM21, CDKN1B, IRF3, IRF8, MNI
mono, 63
null
UBE2D2, UBE2D1, UBE2E1, UBE2E2
Homotrimer
null
90.718042
0.406716
72.121615
0.605844
1,208
P19474
Q13107
16472766, BioGrid E3Net
UbiNet, UbiBrowser, 31181401
TRIM21
MASAARLTMMWEEVTCPICLDPFVEPVSIECGHSFCQECISQVGKGGGSVCPVCRQRFLLKNLRPNRQLANMVNNLKEISQEAREGTQGERCAVHGERLHLFCEKDGKALCWVCAQSRKHRDHAMVPLEEAAQEYQEKLQVALGELRRKQELAEKLEVEIAIKRADWKKTVETQKSRIHAEFVQQKNFLVEEEQRQLQELEKDEREQLRILGEKEAKLAQQSQALQELISELDRRCHSSALELLQEVIIVLERSESWNLKDLDITSPELRSVCHVPGLKKMLRTCAVHITLDPDTANPWLILSEDRRQVRLGDTQQSIPGNEERFDSYPMVLGAQHFHSGKHYWEVDVTGKEAWDLGVCRDSVRRKGHFLLSSKSGFWTIWLWNKQKYEAGTYPQTPLHLQVPPCQVGIFLDYEAGMVSFYNITDHGSLIYSFSECAFTGPLRPFFSPGFNDGGKNTAPLTLCPLNIGSQGSTDY
Homo sapiens
Cytoplasm, Cytoplasmic vesicle, autophagosome, Nucleus, Cytoplasm, P-body, Cytoplasm, Stress granule
Low tissue specificity
{'Ciliated cells': '3.8', 'Basal respiratory cells': '6.8', 'Club cells': '5.8', 'Ionocytes': '3.7', 'Mucus glandular cells': '4.8', 'Serous glandular cells': '2.3', 'Gastric mucus-secreting cells': '8.8', 'Proximal enterocytes': '8.9', 'Paneth cells': '3.9', 'Distal enterocytes': '8.5', 'Intestinal goblet cells': '8.4', 'Exocrine glandular cells': '-0.716', 'Basal prostatic cells': '5.4', 'Prostatic glandular cells': '5.0', 'Breast glandular cells': '0.298', 'Breast myoepithelial cells': '0.351', 'Glandular and luminal cells': '5.9', 'Secretory cells': '8.4', 'Basal keratinocytes': '3.2', 'Suprabasal keratinocytes': '2.7', 'Basal squamous epithelial cells': '6.4', 'Squamous epithelial cells': '4.3', 'Alveolar cells type 1': '0.116', 'Alveolar cells type 2': '0.115', 'Salivary duct cells': '3.0', 'Ductal cells': '0.700', 'Hepatocytes': '0.503', 'Cholangiocytes': '11.4', 'Proximal tubular cells': '0.175', 'Distal tubular cells': '0.0', 'Collecting duct cells': '5.8', 'Mesothelial cells': '0.451', 'Sertoli cells': '0.479', 'Granulosa cells': '4.8', 'Enteroendocrine cells': '3.7', 'Pancreatic endocrine cells': '3.4', 'Leydig cells': '0.632', 'Excitatory neurons': '0.2', 'Inhibitory neurons': '0.1', 'Cone photoreceptor cells': '0.0', 'Rod photoreceptor cells': '0.0', 'Bipolar cells': '0.7', 'Horizontal cells': '0.6', 'Astrocytes': '0.0', 'Oligodendrocyte precursor cells': '0.9', 'Oligodendrocytes': '0.1', 'Microglial cells': '1.8', 'Muller glia cells': '2.4', 'Schwann cells': '0.099', 'Spermatogonia': '0.401', 'Spermatocytes': '-0.062', 'Early spermatids': '-0.578', 'Late spermatids': '-0.618', 'Oocytes': '1.5', 'Cytotrophoblasts': '6.6', 'Syncytiotrophoblasts': '9.8', 'Extravillous trophoblasts': '10.0', 'Endothelial cells': '7.8', 'Lymphatic endothelial cells': '6.9', 'Cardiomyocytes': '0.335', 'Skeletal myocytes': '-0.080', 'Smooth muscle cells': '6.3', 'Adipocytes': '8.3', 'Melanocytes': '0.101', 'Fibroblasts': '6.5', 'Peritubular cells': '0.579', 'Endometrial stromal cells': '4.5', 'Ovarian stromal cells': '6.7', 'Undifferentiated cells': '5.9', 'T-cells': '9.9', 'B-cells': '8.8', 'Plasma cells': '5.0', 'Nk-cells': '15.1', 'Granulocytes': '6.2', 'Monocytes': '7.8', 'Macrophages': '8.5', 'Hofbauer cells': '9.9', 'Kupffer cells': '10.3', 'Dendritic cells': '8.0', 'Langerhans cells': '0.466', 'Erythroid cells': '-0.084', 'Adipocytes (Subcutaneous)': '-0.368', 'Adipocytes (Visceral)': '-0.167', 'Breast glandular cells (progenitors)': '0.190', 'Adipocytes (Breast)': '-0.382', 'Colon enterocytes': '0.004', 'Colon enteroendocrine cells': '0.196', 'Enteric glia cells': '-0.129', 'Mitotic cells (Colon)': '0.005', 'Mitotic cells (Heart)': '0.486', 'Podocytes': '-0.114', 'Ascending Loop of Henle cells': '0.371', 'Intercalated cells': '-0.097', 'Cholangiocyte': '0.375', 'NK-cells (Liver)': '-0.278', 'Respiratory ciliated cells': '-0.022', 'Mitotic cells (Lung)': '0.157', 'NK-cells (Lung)': '0.110', 'B-cells (Lung)': '-0.155', 'Alpha cells': '0.333', 'Beta cells': '0.161', 'Prostate glandular cells': '-0.162', 'Prostate basal glandular cells': '0.286', 'Urothelial cells': '0.283', 'Keratinocyte (other)': '0.121', 'Keratinocyte (granular)': '-0.008', 'Hair cortex cells': '-0.113', 'Inner root sheath cells': '-0.069', 'Outer root sheath cells': '0.125', 'Sebaceous gland cells': '0.110', 'Eccrine sweat gland cells': '0.070', 'Adipocytes (Skin)': '0.019', 'Mitotic cells (Skin)': '0.236', 'Parietal cells': '-0.609', 'Chief cells': '-0.599', 'Gastric mucous cells': '-0.193', 'Gastric enteroendocrine cells': '-0.441', 'Mitotic cells (Stomach)': '0.261', 'Parafollicular cells': '-0.028', 'Thyroid glandular cells': '0.094', 'Mitotic cells (Thyroid)': '0.242', 'Adrenal cortex cells': '0.619', 'Adrenal medulla cells': '0.063', 'Mitotic cells (Adrenal gland)': '0.483', 'Minor salivary glandular cells': '0.582', 'Minor salivary gland ductal cells': '0.072', 'Minor salivary gland basal cells': '0.229', 'Mitotic cells (Minor salivary gland)': '0.376', 'Adipocytes (Minor salivary gland)': '0.211', 'Somatotropes': '-0.121', 'Lactotropes': '-0.287', 'Gonadotropes': '0.004', 'Corticotropes': '-0.352', 'Thyrotropes': '-0.054', 'Undifferentiated cells (Pituitary gland)': '0.486', 'Mitotic cells (Spleen)': '-0.016', 'Platelets': '0.115', 'Erythrocytes': '0.098', 'Hematopoietic stem cells': '0.042', 'B-cells (Spleen)': '0.028', 'NK-cells (Spleen)': '0.157', 'Amygdala excitatory': '0.1', 'Cerebellar inhibitory': '0.2', 'Cge interneuron': '0.3', 'Deep-layer corticothalamic and 6b': '0.3', 'Deep-layer intratelencephalic': '0.1', 'Deep-layer near-projecting': '0.1', 'Eccentric medium spiny neuron': '0.4', 'Hippocampal ca1-3': '0.5', 'Hippocampal ca4': '0.1', 'Hippocampal dentate gyrus': '0.3', 'Lamp5-lhx6 and chandelier': '0.3', 'Lower rhombic lip': '0.2', 'Mammillary body': '0.4', 'Medium spiny neuron': '0.6', 'Mge interneuron': '0.1', 'Midbrain-derived inhibitory': '0.6', 'Miscellaneous': '0.6', 'Splatter': '0.5', 'Thalamic excitatory': '1.3', 'Upper rhombic lip': '0.1', 'Upper-layer intratelencephalic': '0.1', 'Astrocyte': '1.5', 'Bergmann glia': '1.5', 'Central nervous system macrophage': '6.0', 'Choroid plexus epithelial cell': '2.9', 'Committed oligodendrocyte precursor': '1.0', 'Ependymal cell': '1.3', 'Oligodendrocyte': '0.1', 'Oligodendrocyte precursor cell': '2.3', 'Endothelial cell': '6.4', 'Pericyte': '5.3', 'Vascular associated smooth muscle cell': '3.1', 'Fibroblast': '5.3', 'Leukocyte': '7.4', 'Basophil': '107.0', 'Eosinophil': '312.5', 'Neutrophil': '496.9', 'Classical monocyte': '25.8', 'Non-classical monocyte': '66.1', 'Intermediate monocyte': '117.0', 'T-reg': '72.1', 'GdT-cell': '89.5', 'MAIT T-cell': '61.2', 'Memory CD4 T-cell': '76.8', 'Naive CD4 T-cell': '47.0', 'Memory CD8 T-cell': '81.1', 'Naive CD8 T-cell': '43.5', 'Memory B-cell': '50.4', 'Naive B-cell': '38.5', 'Plasmacytoid DC': '47.5', 'Myeloid DC': '92.2', 'NK-cell': '88.9', 'Total PBMC': '83.8', 'Vd2 gdTCR': '67.8', 'Memory CD4 T-cell Th1\\/Th17': '48.0', 'Memory CD4 T-cell Th17': '54.6', 'Memory CD4 T-cell Th2': '54.8', 'Non-Vd2 gdTCR': '73.7', 'Memory CD4 T-cell Th1': '58.8', 'Memory CD4 T-cell TFH': '61.9', 'Terminal effector memory CD4 T-cell': '72.8', 'Central memory CD8 T-cell': '59.9', 'Effector memory CD8 T-cell': '90.7', 'Terminal effector memory CD8 T-cell': '75.8', 'Non-switched memory B-cell': '52.6', 'Plasmablast': '62.3', 'Switched memory B-cell': '55.8', 'Exhausted memory B-cell': '52.1', 'Progenitor cell': '44.7', 'Memory T-reg': '82.4', 'Naive CD4 T-cell activated': '133.9', 'Naive CD8 T-cell activated': '163.4', 'Naive T-reg': '54.7'}
2IWG, 5JPX, 5OLM, 6FGA, 6S53, 7BBD, 8A58
{'Adipose Tissue': 21.42795099667774, 'Adrenal Gland': 16.707763565891472, 'Bladder': 21.861904761904764, 'Blood': 61.11958557588805, 'Blood Vessel': 22.62928389513109, 'Brain': 4.305000416351249, 'Breast': 20.001740740740743, 'Cervix Uteri': 26.420526315789473, 'Colon': 23.40817458279846, 'Esophagus': 21.74157577854671, 'Fallopian Tube': 25.39, 'Heart': 6.66628106852497, 'Kidney': 13.61479775280899, 'Liver': 10.388, 'Lung': 32.00464878892734, 'Muscle': 3.944284806973848, 'Nerve': 25.39305008077545, 'Ovary': 30.51811111111111, 'Pancreas': 6.808080182926829, 'Pituitary': 12.995699646643107, 'Prostate': 21.00597551020408, 'Salivary Gland': 16.434148148148147, 'Skin': 17.851811498065228, 'Small Intestine': 28.907085561497325, 'Spleen': 50.16024896265561, 'Stomach': 19.072721448467966, 'Testis': 6.377013850415512, 'Thyroid': 21.553307810107196, 'Uterus': 29.83549295774648, 'Vagina': 21.551141025641027}
USP4
MAEGGGCRERPDAETQKSELGPLMRTTLQRGAQWYLIDSRWFKQWKKYVGFDSWDMYNVGEHNLFPGPIDNSGLFSDPESQTLKEHLIDELDYVLVPTEAWNKLLNWYGCVEGQQPIVRKVVEHGLFVKHCKVEVYLLELKLCENSDPTNVLSCHFSKADTIATIEKEMRKLFNIPAERETRLWNKYMSNTYEQLSKLDNTVQDAGLYQGQVLVIEPQNEDGTWPRQTLQSKSSTAPSRNFTTSPKSSASPYSSVSASLIANGDSTSTCGMHSSGVSRGGSGFSASYNCQEPPSSHIQPGLCGLGNLGNTCFMNSALQCLSNTAPLTDYFLKDEYEAEINRDNPLGMKGEIAEAYAELIKQMWSGRDAHVAPRMFKTQVGRFAPQFSGYQQQDSQELLAFLLDGLHEDLNRVKKKPYLELKDANGRPDAVVAKEAWENHRLRNDSVIVDTFHGLFKSTLVCPECAKVSVTFDPFCYLTLPLPLKKDRVMEVFLVPADPHCRPTQYRVTVPLMGAVSDLCEALSRLSGIAAENMVVADVYNHRFHKIFQMDEGLNHIMPRDDIFVYEVCSTSVDGSECVTLPVYFRERKSRPSSTSSASALYGQPLLLSVPKHKLTLESLYQAVCDRISRYVKQPLPDEFGSSPLEPGACNGSRNSCEGEDEEEMEHQEEGKEQLSETEGSGEDEPGNDPSETTQKKIKGQPCPKRLFTFSLVNSYGTADINSLAADGKLLKLNSRSTLAMDWDSETRRLYYDEQESEAYEKHVSMLQPQKKKKTTVALRDCIELFTTMETLGEHDPWYCPNCKKHQQATKKFDLWSLPKILVVHLKRFSYNRYWRDKLDTVVEFPIRGLNMSEFVCNLSARPYVYDLIAVSNHYGAMGVGHYTAYAKNKLNGKWYYFDDSNVSLASEDQIVTKAAYVLFYQRRDDEFYKTPSLSSSGSSDGGTRPSSSQQGFGDDEACSMDTN
Homo sapiens
Cytoplasm, Nucleus
Low tissue specificity
{'Ciliated cells': '22.2', 'Basal respiratory cells': '19.0', 'Club cells': '21.5', 'Ionocytes': '15.5', 'Mucus glandular cells': '27.7', 'Serous glandular cells': '24.1', 'Gastric mucus-secreting cells': '21.8', 'Proximal enterocytes': '15.5', 'Paneth cells': '16.5', 'Distal enterocytes': '14.6', 'Intestinal goblet cells': '19.6', 'Exocrine glandular cells': '-0.777', 'Basal prostatic cells': '20.3', 'Prostatic glandular cells': '19.7', 'Breast glandular cells': '0.445', 'Breast myoepithelial cells': '0.386', 'Glandular and luminal cells': '21.9', 'Secretory cells': '13.1', 'Basal keratinocytes': '22.0', 'Suprabasal keratinocytes': '30.9', 'Basal squamous epithelial cells': '18.6', 'Squamous epithelial cells': '17.3', 'Alveolar cells type 1': '0.079', 'Alveolar cells type 2': '-0.458', 'Salivary duct cells': '23.5', 'Ductal cells': '0.680', 'Hepatocytes': '0.413', 'Cholangiocytes': '13.4', 'Proximal tubular cells': '0.166', 'Distal tubular cells': '18.4', 'Collecting duct cells': '33.1', 'Mesothelial cells': '0.316', 'Sertoli cells': '0.003', 'Granulosa cells': '23.2', 'Enteroendocrine cells': '12.4', 'Pancreatic endocrine cells': '18.7', 'Leydig cells': '-0.141', 'Excitatory neurons': '29.8', 'Inhibitory neurons': '25.3', 'Cone photoreceptor cells': '23.8', 'Rod photoreceptor cells': '22.6', 'Bipolar cells': '20.0', 'Horizontal cells': '17.0', 'Astrocytes': '26.6', 'Oligodendrocyte precursor cells': '24.1', 'Oligodendrocytes': '18.8', 'Microglial cells': '16.1', 'Muller glia cells': '15.7', 'Schwann cells': '0.135', 'Spermatogonia': '0.068', 'Spermatocytes': '0.276', 'Early spermatids': '0.579', 'Late spermatids': '0.283', 'Oocytes': '27.2', 'Cytotrophoblasts': '25.4', 'Syncytiotrophoblasts': '29.0', 'Extravillous trophoblasts': '16.5', 'Endothelial cells': '24.1', 'Lymphatic endothelial cells': '17.0', 'Cardiomyocytes': '0.611', 'Skeletal myocytes': '-0.041', 'Smooth muscle cells': '20.3', 'Adipocytes': '25.7', 'Melanocytes': '0.240', 'Fibroblasts': '18.6', 'Peritubular cells': '0.020', 'Endometrial stromal cells': '18.4', 'Ovarian stromal cells': '16.9', 'Undifferentiated cells': '14.1', 'T-cells': '30.4', 'B-cells': '27.8', 'Plasma cells': '27.3', 'Nk-cells': '31.1', 'Granulocytes': '22.7', 'Monocytes': '46.6', 'Macrophages': '41.3', 'Hofbauer cells': '30.9', 'Kupffer cells': '42.5', 'Dendritic cells': '45.8', 'Langerhans cells': '0.386', 'Erythroid cells': '0.034', 'Adipocytes (Subcutaneous)': '-0.030', 'Adipocytes (Visceral)': '-0.320', 'Breast glandular cells (progenitors)': '0.274', 'Adipocytes (Breast)': '-0.321', 'Colon enterocytes': '-0.277', 'Colon enteroendocrine cells': '0.297', 'Enteric glia cells': '0.468', 'Mitotic cells (Colon)': '-0.153', 'Mitotic cells (Heart)': '0.501', 'Podocytes': '-0.032', 'Ascending Loop of Henle cells': '0.438', 'Intercalated cells': '0.031', 'Cholangiocyte': '0.370', 'NK-cells (Liver)': '-0.239', 'Respiratory ciliated cells': '0.152', 'Mitotic cells (Lung)': '-0.098', 'NK-cells (Lung)': '0.479', 'B-cells (Lung)': '0.181', 'Alpha cells': '0.401', 'Beta cells': '0.232', 'Prostate glandular cells': '-0.120', 'Prostate basal glandular cells': '0.176', 'Urothelial cells': '0.127', 'Keratinocyte (other)': '0.529', 'Keratinocyte (granular)': '0.081', 'Hair cortex cells': '-0.151', 'Inner root sheath cells': '-0.079', 'Outer root sheath cells': '0.041', 'Sebaceous gland cells': '-0.034', 'Eccrine sweat gland cells': '-0.244', 'Adipocytes (Skin)': '-0.328', 'Mitotic cells (Skin)': '0.377', 'Parietal cells': '-0.683', 'Chief cells': '-0.632', 'Gastric mucous cells': '-0.391', 'Gastric enteroendocrine cells': '-0.445', 'Mitotic cells (Stomach)': '0.021', 'Parafollicular cells': '0.060', 'Thyroid glandular cells': '0.223', 'Mitotic cells (Thyroid)': '0.143', 'Adrenal cortex cells': '0.277', 'Adrenal medulla cells': '-0.011', 'Mitotic cells (Adrenal gland)': '0.178', 'Minor salivary glandular cells': '0.453', 'Minor salivary gland ductal cells': '-0.021', 'Minor salivary gland basal cells': '0.579', 'Mitotic cells (Minor salivary gland)': '0.632', 'Adipocytes (Minor salivary gland)': '0.231', 'Somatotropes': '-0.157', 'Lactotropes': '-0.262', 'Gonadotropes': '0.090', 'Corticotropes': '-0.337', 'Thyrotropes': '-0.124', 'Undifferentiated cells (Pituitary gland)': '0.477', 'Mitotic cells (Spleen)': '-0.292', 'Platelets': '-0.165', 'Erythrocytes': '-0.030', 'Hematopoietic stem cells': '-0.322', 'B-cells (Spleen)': '0.388', 'NK-cells (Spleen)': '0.456', 'Amygdala excitatory': '57.3', 'Cerebellar inhibitory': '47.5', 'Cge interneuron': '49.6', 'Deep-layer corticothalamic and 6b': '47.2', 'Deep-layer intratelencephalic': '56.9', 'Deep-layer near-projecting': '55.3', 'Eccentric medium spiny neuron': '61.9', 'Hippocampal ca1-3': '48.3', 'Hippocampal ca4': '44.6', 'Hippocampal dentate gyrus': '69.2', 'Lamp5-lhx6 and chandelier': '50.8', 'Lower rhombic lip': '53.2', 'Mammillary body': '45.3', 'Medium spiny neuron': '80.2', 'Mge interneuron': '55.2', 'Midbrain-derived inhibitory': '44.1', 'Miscellaneous': '55.1', 'Splatter': '44.2', 'Thalamic excitatory': '45.5', 'Upper rhombic lip': '44.6', 'Upper-layer intratelencephalic': '63.9', 'Astrocyte': '57.4', 'Bergmann glia': '32.4', 'Central nervous system macrophage': '136.5', 'Choroid plexus epithelial cell': '67.9', 'Committed oligodendrocyte precursor': '50.4', 'Ependymal cell': '53.2', 'Oligodendrocyte': '44.5', 'Oligodendrocyte precursor cell': '46.5', 'Endothelial cell': '65.6', 'Pericyte': '59.9', 'Vascular associated smooth muscle cell': '50.8', 'Fibroblast': '50.6', 'Leukocyte': '83.9', 'Basophil': '169.6', 'Eosinophil': '95.1', 'Neutrophil': '463.2', 'Classical monocyte': '114.8', 'Non-classical monocyte': '127.0', 'Intermediate monocyte': '150.5', 'T-reg': '107.0', 'GdT-cell': '48.3', 'MAIT T-cell': '118.4', 'Memory CD4 T-cell': '50.4', 'Naive CD4 T-cell': '100.4', 'Memory CD8 T-cell': '49.0', 'Naive CD8 T-cell': '84.8', 'Memory B-cell': '51.2', 'Naive B-cell': '86.6', 'Plasmacytoid DC': '117.7', 'Myeloid DC': '134.5', 'NK-cell': '95.4', 'Total PBMC': '119.8', 'Vd2 gdTCR': '118.2', 'Memory CD4 T-cell Th1\\/Th17': '89.9', 'Memory CD4 T-cell Th17': '99.6', 'Memory CD4 T-cell Th2': '100.4', 'Non-Vd2 gdTCR': '114.7', 'Memory CD4 T-cell Th1': '92.0', 'Memory CD4 T-cell TFH': '98.9', 'Terminal effector memory CD4 T-cell': '102.1', 'Central memory CD8 T-cell': '104.3', 'Effector memory CD8 T-cell': '123.0', 'Terminal effector memory CD8 T-cell': '109.1', 'Non-switched memory B-cell': '109.2', 'Plasmablast': '92.4', 'Switched memory B-cell': '87.4', 'Exhausted memory B-cell': '100.4', 'Progenitor cell': '88.5', 'Memory T-reg': '96.0', 'Naive CD4 T-cell activated': '94.5', 'Naive CD8 T-cell activated': '91.1', 'Naive T-reg': '80.6'}
2Y6E, 5CTR
{'Adipose Tissue': 27.898247508305648, 'Adrenal Gland': 17.445631782945735, 'Bladder': 31.25142857142857, 'Blood': 39.43077502691066, 'Blood Vessel': 33.27881647940075, 'Brain': 18.700019682059047, 'Breast': 28.6102614379085, 'Cervix Uteri': 37.11157894736842, 'Colon': 24.936695763799744, 'Esophagus': 27.178320415224917, 'Fallopian Tube': 32.291111111111114, 'Heart': 12.57390824622532, 'Kidney': 15.054606741573032, 'Liver': 8.924190265486725, 'Lung': 39.091418685121106, 'Muscle': 12.801387297633871, 'Nerve': 39.231147011308565, 'Ovary': 32.358111111111114, 'Pancreas': 8.251408536585366, 'Pituitary': 20.74756183745583, 'Prostate': 30.07522448979592, 'Salivary Gland': 20.357469135802468, 'Skin': 32.37302929795467, 'Small Intestine': 24.402032085561498, 'Spleen': 37.54157676348548, 'Stomach': 17.181211699164347, 'Testis': 34.808448753462606, 'Thyroid': 33.271163859111795, 'Uterus': 38.25401408450704, 'Vagina': 31.537884615384616}
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[1.0, 1.0, 1.0, 1.0, 0.92, 0.89, 0.93, 0.88, 0.93, 0.46, 0.29, 0.6, 0.23, 0.79, 0.34, 0.01, 0.32, 0.64, 0.36, 0.0, 0.1, 0.58, 0.14, 0.28, 0.76, 0.46, 0.74, 0.34, 0.67, 0.67, 0.59, 0.3, 0.48, 0.07, 0.14, 0.0, 0.0, 0.03, 0.02, 0.62, 0.06, 0.06, 0.41, 0.31, 0.0, 0.25, 0.44, 0.18, 0.04, 0.05, 0.25, 0.26, 0.76, 0.78, 0.37, 0.67, 0.91, 0.47, 0.39, 0.48, 0.37, 0.83, 0.78, 0.18, 0.35, 0.15, 0.22, 0.45, 0.0, 0.31, 0.0, 0.42, 0.27, 0.01, 0.08, 0.53, 0.39, 0.73, 0.63, 0.57, 0.24, 0.45, 0.16, 0.42, 0.85, 0.86, 0.11, 0.52, 0.46, 0.75, 0.61, 0.35, 0.08, 0.16, 0.2, 0.0, 0.1, 0.3, 0.62, 0.0, 0.03, 0.45, 0.29, 0.0, 0.38, 0.74, 0.13, 0.09, 0.32, 0.26, 0.38, 0.96, 0.72, 0.2, 0.72, 0.49, 0.05, 0.43, 0.31, 0.64, 0.03, 0.14, 0.31, 0.32, 0.26, 0.33, 0.81, 0.81, 0.46, 0.52, 0.32, 0.55, 0.1, 0.11, 0.13, 0.36, 0.47, 0.09, 0.22, 0.0, 0.36, 0.0, 0.02, 0.22, 0.26, 0.67, 0.43, 0.56, 0.82, 0.42, 0.43, 0.32, 0.51, 0.2, 0.62, 0.05, 0.15, 0.31, 0.47, 0.29, 0.3, 0.0, 0.38, 0.39, 0.0, 0.14, 0.74, 0.32, 0.0, 0.17, 0.66, 0.38, 0.14, 0.77, 0.1, 0.45, 0.81, 0.89, 0.37, 0.57, 0.19, 0.28, 0.04, 0.16, 0.0, 0.27, 0.38, 0.76, 0.7, 0.9, 0.52, 0.35, 0.47, 0.39, 0.11, 0.71, 0.67, 0.38, 0.86, 0.29, 0.18, 0.0, 0.13, 0.31, 0.19, 0.17, 0.11, 0.5, 0.54, 0.29, 0.02, 0.26, 0.0, 0.03, 0.0, 0.01, 0.15, 0.21, 0.39, 0.9, 0.7, 0.42, 0.17, 0.08, 0.45, 0.39, 0.56, 0.85, 0.71, 0.92, 0.93, 0.98, 0.93, 1.0, 1.0, 0.99, 0.98, 0.89, 0.94, 0.86, 0.87, 0.8, 0.89, 0.84, 0.99, 0.99, 1.0, 0.99, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 0.88, 1.0, 0.92, 1.0, 0.98, 1.0, 0.96, 1.0, 0.98, 1.0, 0.99, 1.0, 0.86, 1.0, 0.95, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 0.98, 1.0, 0.96, 0.99, 0.96, 0.76, 0.84, 0.84, 0.74, 0.83, 0.76, 0.96, 0.81, 0.95, 0.76, 0.78, 0.84, 0.3, 0.46, 0.3, 0.0, 0.15, 0.01, 0.0, 0.0, 0.21, 0.41, 0.21, 0.31, 0.35, 0.01, 0.05, 0.04, 0.04, 0.03, 0.02, 0.03, 0.02, 0.02, 0.0, 0.0, 0.01, 0.04, 0.0, 0.18, 0.3, 0.0, 0.0, 0.35, 0.06, 0.0, 0.38, 0.62, 0.42, 0.44, 0.1, 0.7, 0.85, 0.2, 0.15, 0.01, 0.5, 0.83, 0.09, 0.9, 0.55, 0.28, 0.09, 0.56, 0.0, 0.21, 0.0, 0.0, 0.35, 0.12, 0.02, 0.0, 0.49, 0.04, 0.01, 0.33, 0.32, 0.03, 0.09, 0.29, 0.1, 0.77, 0.43, 0.48, 0.67, 0.11, 0.56, 0.02, 0.59, 0.65, 0.02, 0.15, 0.65, 0.16, 0.02, 0.14, 0.63, 0.35, 0.02, 0.62, 0.66, 0.04, 0.19, 0.41, 0.39, 0.75, 0.22, 0.25, 0.08, 0.02, 0.18, 0.47, 0.0, 0.05, 0.21, 0.18, 0.01, 0.01, 0.54, 0.0, 0.02, 0.06, 0.07, 0.0, 0.0, 0.0, 0.3, 0.16, 0.5, 0.9, 0.25, 0.36, 0.92, 0.35, 0.73, 0.86, 0.63, 0.2, 0.08, 0.73, 0.94, 0.33, 0.67, 0.28, 0.56, 0.53, 0.03, 0.02, 0.59, 0.29, 0.25, 0.29, 0.48, 0.28, 0.16, 0.43, 0.53, 0.41, 0.12, 0.16, 0.0, 0.07, 0.01, 0.04, 0.53, 0.06, 0.0, 0.13, 0.0, 0.02, 0.17, 0.18, 0.06, 0.19, 0.13, 0.27, 0.04, 0.63, 0.58, 0.4, 0.64, 0.17, 0.57, 0.15, 0.14, 0.35, 0.07, 0.29, 0.4, 0.05, 0.27, 0.31, 0.02, 0.31, 0.0, 0.31, 0.06, 0.38, 0.66, 0.63, 0.8, 0.61, 0.24, 0.57, 0.05, 0.42, 0.0, 0.14, 0.04, 0.14, 0.18, 0.3, 0.48, 0.22, 0.74, 0.47, 0.39, 0.06, 0.18, 0.11, 0.09, 0.2, 0.03, 0.62, 0.03, 0.42, 0.45, 0.97, 0.04, 0.23, 0.01, 0.37, 0.33, 0.01, 0.02, 0.52, 0.1, 0.01, 0.23, 0.73, 0.38, 0.28, 0.83, 0.15, 0.45, 0.22, 0.85, 0.21, 0.03, 0.24, 0.02, 0.0, 0.1, 0.13, 0.69, 0.8, 0.33, 0.3, 0.08, 0.61, 0.35, 0.45, 0.09, 0.62, 0.35, 0.8, 0.24, 0.21, 0.02, 0.55, 0.51, 0.01, 0.45, 0.88, 0.94, 0.3, 0.5, 0.02, 0.09, 0.0, 0.02, 0.25, 0.12, 0.48, 0.58, 0.72, 0.22, 0.99, 0.62, 0.74, 0.26, 0.52, 0.23, 0.12, 0.29, 0.0, 0.13, 0.03, 0.02, 0.0, 0.01, 0.12, 0.35, 0.56, 0.87, 0.72, 0.91, 0.83, 0.36, 0.97, 0.73, 0.67, 0.59, 0.27, 0.39, 0.22, 0.05, 0.13, 0.27, 0.01, 0.17, 0.04, 0.06, 0.28, 0.05, 0.39, 0.54, 0.64, 0.61, 0.07, 0.35, 0.09, 0.59, 0.37, 0.0, 0.11, 0.56, 0.24, 0.01, 0.22, 0.45, 0.21, 0.0, 0.39, 0.23, 0.09, 0.15, 0.52, 0.89, 0.36, 0.72, 0.86, 0.93, 0.67, 0.65, 0.79, 1.0, 0.98, 1.0, 0.95, 0.99, 0.95, 0.95, 0.99, 1.0, 0.99, 1.0, 1.0, 1.0, 1.0, 0.94, 1.0, 0.96, 0.98, 1.0, 0.97, 0.99, 0.79, 0.99, 0.59, 0.99, 0.73, 0.98, 0.93, 0.84, 0.7, 0.64, 0.96, 0.79, 0.99, 0.99, 1.0, 1.0, 0.94, 1.0, 0.9, 1.0, 0.98, 1.0, 0.98, 0.96, 0.93, 0.91, 0.98, 0.92, 0.92, 0.94, 0.92, 0.82, 0.97, 0.94, 0.99, 0.98, 0.99, 0.9, 0.94, 0.93, 0.92, 0.91, 0.79, 0.4, 0.11, 0.03, 0.6, 0.04, 0.01, 0.18, 0.03, 0.27, 0.61, 0.58, 0.0, 0.53, 0.48, 0.47, 0.6, 0.64, 0.77, 0.19, 0.75, 0.72, 0.63, 0.74, 0.68, 0.64, 0.16, 0.92, 0.17, 0.53, 0.73, 0.92, 0.1, 0.08, 0.0, 0.0, 0.0, 0.05, 0.01, 0.46, 0.19, 0.66, 0.18, 0.21, 0.71, 0.76, 0.18, 0.1, 0.32, 0.46, 0.83, 0.24, 0.05, 0.49, 0.2, 0.47, 0.55, 0.6, 0.22, 0.67, 0.11, 0.17, 0.73, 0.67, 0.8, 0.57, 0.85, 0.74, 0.84, 0.77, 0.47, 0.54, 0.12, 0.35, 0.03, 0.44, 0.39, 0.0, 0.03, 0.39, 0.37, 0.13, 0.19, 0.52, 0.59, 0.55, 0.67, 0.09, 0.37, 0.79, 0.97, 0.6, 0.32, 0.19, 0.55, 0.0, 0.48, 0.66, 0.3, 0.72, 0.52, 0.61, 0.07, 0.44, 0.0, 0.28, 0.23, 0.26, 0.16, 0.23, 0.0, 0.12, 0.33, 0.04, 0.03, 0.23, 0.0, 0.01, 0.0, 0.04, 0.06, 0.0, 0.5, 0.01, 0.1, 0.44, 0.55, 0.46, 1.0, 0.94, 0.42, 0.58, 0.48, 0.16, 0.24, 0.38, 0.18, 0.27, 0.0, 0.44, 0.05, 0.38, 0.17, 0.63, 0.46, 0.08, 0.37, 0.01, 0.35, 0.65, 0.13, 0.12, 0.33, 0.24, 0.9, 0.73, 0.31, 0.22, 0.45, 0.06, 0.17, 0.0, 0.25, 0.01, 0.1, 0.0, 0.0, 0.03, 0.0, 0.01, 0.39, 0.53, 0.53, 0.13, 0.79, 0.87, 0.13, 0.32, 0.05, 0.01, 0.0, 0.09, 0.0, 0.23, 0.01, 0.38, 0.62, 0.35, 0.47, 0.54, 0.03, 0.13, 0.2, 0.03, 0.32, 0.14, 0.4, 0.67, 0.32, 0.49, 0.66, 0.18, 0.37, 0.27, 0.82, 0.47, 0.0, 0.26, 0.31, 0.47, 0.07, 0.0, 0.0, 0.01, 0.0, 0.01, 0.0, 0.3, 0.17, 0.33, 0.46, 0.52, 0.7, 0.91, 0.17, 0.67, 0.66, 0.72, 0.86, 0.9, 0.82, 0.85, 0.88, 0.86, 0.94, 1.0, 1.0, 1.0, 0.99, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 0.99, 1.0, 0.98, 1.0, 0.99, 1.0, 0.99, 1.0, 0.98, 0.99, 0.98, 0.97, 1.0, 0.99]
RING finger
Component of a SCF(SKP2)-like complex containing CUL1, SKP1, TRIM21 and SKP2.
SCF
null
IRF8, CALR, CUL1, FBXW11, HSPA5, IKBKB, IRF3, SKP1 , VCP,SKP2, DCP2 ,ULK1, BECN1,GABARAP, GABARAPL1, GABARAPL2 , MAP1LC3C,SQSTM1,IRF3 , NMI, IFI35 , CUL1, TRIM21
USP4, IKBKB, TRIM21, CDKN1B, IRF3, IRF8, MNI
mono, 63
null
UBE2D2, UBE2D1, UBE2E1, UBE2E2
Homotrimer
null
90.718042
0.406716
76.389834
0.438598
528
P19474
Q13501
39172027
Manual
TRIM21
MASAARLTMMWEEVTCPICLDPFVEPVSIECGHSFCQECISQVGKGGGSVCPVCRQRFLLKNLRPNRQLANMVNNLKEISQEAREGTQGERCAVHGERLHLFCEKDGKALCWVCAQSRKHRDHAMVPLEEAAQEYQEKLQVALGELRRKQELAEKLEVEIAIKRADWKKTVETQKSRIHAEFVQQKNFLVEEEQRQLQELEKDEREQLRILGEKEAKLAQQSQALQELISELDRRCHSSALELLQEVIIVLERSESWNLKDLDITSPELRSVCHVPGLKKMLRTCAVHITLDPDTANPWLILSEDRRQVRLGDTQQSIPGNEERFDSYPMVLGAQHFHSGKHYWEVDVTGKEAWDLGVCRDSVRRKGHFLLSSKSGFWTIWLWNKQKYEAGTYPQTPLHLQVPPCQVGIFLDYEAGMVSFYNITDHGSLIYSFSECAFTGPLRPFFSPGFNDGGKNTAPLTLCPLNIGSQGSTDY
Homo sapiens
Cytoplasm, Cytoplasmic vesicle, autophagosome, Nucleus, Cytoplasm, P-body, Cytoplasm, Stress granule
Low tissue specificity
{'Ciliated cells': '3.8', 'Basal respiratory cells': '6.8', 'Club cells': '5.8', 'Ionocytes': '3.7', 'Mucus glandular cells': '4.8', 'Serous glandular cells': '2.3', 'Gastric mucus-secreting cells': '8.8', 'Proximal enterocytes': '8.9', 'Paneth cells': '3.9', 'Distal enterocytes': '8.5', 'Intestinal goblet cells': '8.4', 'Exocrine glandular cells': '-0.716', 'Basal prostatic cells': '5.4', 'Prostatic glandular cells': '5.0', 'Breast glandular cells': '0.298', 'Breast myoepithelial cells': '0.351', 'Glandular and luminal cells': '5.9', 'Secretory cells': '8.4', 'Basal keratinocytes': '3.2', 'Suprabasal keratinocytes': '2.7', 'Basal squamous epithelial cells': '6.4', 'Squamous epithelial cells': '4.3', 'Alveolar cells type 1': '0.116', 'Alveolar cells type 2': '0.115', 'Salivary duct cells': '3.0', 'Ductal cells': '0.700', 'Hepatocytes': '0.503', 'Cholangiocytes': '11.4', 'Proximal tubular cells': '0.175', 'Distal tubular cells': '0.0', 'Collecting duct cells': '5.8', 'Mesothelial cells': '0.451', 'Sertoli cells': '0.479', 'Granulosa cells': '4.8', 'Enteroendocrine cells': '3.7', 'Pancreatic endocrine cells': '3.4', 'Leydig cells': '0.632', 'Excitatory neurons': '0.2', 'Inhibitory neurons': '0.1', 'Cone photoreceptor cells': '0.0', 'Rod photoreceptor cells': '0.0', 'Bipolar cells': '0.7', 'Horizontal cells': '0.6', 'Astrocytes': '0.0', 'Oligodendrocyte precursor cells': '0.9', 'Oligodendrocytes': '0.1', 'Microglial cells': '1.8', 'Muller glia cells': '2.4', 'Schwann cells': '0.099', 'Spermatogonia': '0.401', 'Spermatocytes': '-0.062', 'Early spermatids': '-0.578', 'Late spermatids': '-0.618', 'Oocytes': '1.5', 'Cytotrophoblasts': '6.6', 'Syncytiotrophoblasts': '9.8', 'Extravillous trophoblasts': '10.0', 'Endothelial cells': '7.8', 'Lymphatic endothelial cells': '6.9', 'Cardiomyocytes': '0.335', 'Skeletal myocytes': '-0.080', 'Smooth muscle cells': '6.3', 'Adipocytes': '8.3', 'Melanocytes': '0.101', 'Fibroblasts': '6.5', 'Peritubular cells': '0.579', 'Endometrial stromal cells': '4.5', 'Ovarian stromal cells': '6.7', 'Undifferentiated cells': '5.9', 'T-cells': '9.9', 'B-cells': '8.8', 'Plasma cells': '5.0', 'Nk-cells': '15.1', 'Granulocytes': '6.2', 'Monocytes': '7.8', 'Macrophages': '8.5', 'Hofbauer cells': '9.9', 'Kupffer cells': '10.3', 'Dendritic cells': '8.0', 'Langerhans cells': '0.466', 'Erythroid cells': '-0.084', 'Adipocytes (Subcutaneous)': '-0.368', 'Adipocytes (Visceral)': '-0.167', 'Breast glandular cells (progenitors)': '0.190', 'Adipocytes (Breast)': '-0.382', 'Colon enterocytes': '0.004', 'Colon enteroendocrine cells': '0.196', 'Enteric glia cells': '-0.129', 'Mitotic cells (Colon)': '0.005', 'Mitotic cells (Heart)': '0.486', 'Podocytes': '-0.114', 'Ascending Loop of Henle cells': '0.371', 'Intercalated cells': '-0.097', 'Cholangiocyte': '0.375', 'NK-cells (Liver)': '-0.278', 'Respiratory ciliated cells': '-0.022', 'Mitotic cells (Lung)': '0.157', 'NK-cells (Lung)': '0.110', 'B-cells (Lung)': '-0.155', 'Alpha cells': '0.333', 'Beta cells': '0.161', 'Prostate glandular cells': '-0.162', 'Prostate basal glandular cells': '0.286', 'Urothelial cells': '0.283', 'Keratinocyte (other)': '0.121', 'Keratinocyte (granular)': '-0.008', 'Hair cortex cells': '-0.113', 'Inner root sheath cells': '-0.069', 'Outer root sheath cells': '0.125', 'Sebaceous gland cells': '0.110', 'Eccrine sweat gland cells': '0.070', 'Adipocytes (Skin)': '0.019', 'Mitotic cells (Skin)': '0.236', 'Parietal cells': '-0.609', 'Chief cells': '-0.599', 'Gastric mucous cells': '-0.193', 'Gastric enteroendocrine cells': '-0.441', 'Mitotic cells (Stomach)': '0.261', 'Parafollicular cells': '-0.028', 'Thyroid glandular cells': '0.094', 'Mitotic cells (Thyroid)': '0.242', 'Adrenal cortex cells': '0.619', 'Adrenal medulla cells': '0.063', 'Mitotic cells (Adrenal gland)': '0.483', 'Minor salivary glandular cells': '0.582', 'Minor salivary gland ductal cells': '0.072', 'Minor salivary gland basal cells': '0.229', 'Mitotic cells (Minor salivary gland)': '0.376', 'Adipocytes (Minor salivary gland)': '0.211', 'Somatotropes': '-0.121', 'Lactotropes': '-0.287', 'Gonadotropes': '0.004', 'Corticotropes': '-0.352', 'Thyrotropes': '-0.054', 'Undifferentiated cells (Pituitary gland)': '0.486', 'Mitotic cells (Spleen)': '-0.016', 'Platelets': '0.115', 'Erythrocytes': '0.098', 'Hematopoietic stem cells': '0.042', 'B-cells (Spleen)': '0.028', 'NK-cells (Spleen)': '0.157', 'Amygdala excitatory': '0.1', 'Cerebellar inhibitory': '0.2', 'Cge interneuron': '0.3', 'Deep-layer corticothalamic and 6b': '0.3', 'Deep-layer intratelencephalic': '0.1', 'Deep-layer near-projecting': '0.1', 'Eccentric medium spiny neuron': '0.4', 'Hippocampal ca1-3': '0.5', 'Hippocampal ca4': '0.1', 'Hippocampal dentate gyrus': '0.3', 'Lamp5-lhx6 and chandelier': '0.3', 'Lower rhombic lip': '0.2', 'Mammillary body': '0.4', 'Medium spiny neuron': '0.6', 'Mge interneuron': '0.1', 'Midbrain-derived inhibitory': '0.6', 'Miscellaneous': '0.6', 'Splatter': '0.5', 'Thalamic excitatory': '1.3', 'Upper rhombic lip': '0.1', 'Upper-layer intratelencephalic': '0.1', 'Astrocyte': '1.5', 'Bergmann glia': '1.5', 'Central nervous system macrophage': '6.0', 'Choroid plexus epithelial cell': '2.9', 'Committed oligodendrocyte precursor': '1.0', 'Ependymal cell': '1.3', 'Oligodendrocyte': '0.1', 'Oligodendrocyte precursor cell': '2.3', 'Endothelial cell': '6.4', 'Pericyte': '5.3', 'Vascular associated smooth muscle cell': '3.1', 'Fibroblast': '5.3', 'Leukocyte': '7.4', 'Basophil': '107.0', 'Eosinophil': '312.5', 'Neutrophil': '496.9', 'Classical monocyte': '25.8', 'Non-classical monocyte': '66.1', 'Intermediate monocyte': '117.0', 'T-reg': '72.1', 'GdT-cell': '89.5', 'MAIT T-cell': '61.2', 'Memory CD4 T-cell': '76.8', 'Naive CD4 T-cell': '47.0', 'Memory CD8 T-cell': '81.1', 'Naive CD8 T-cell': '43.5', 'Memory B-cell': '50.4', 'Naive B-cell': '38.5', 'Plasmacytoid DC': '47.5', 'Myeloid DC': '92.2', 'NK-cell': '88.9', 'Total PBMC': '83.8', 'Vd2 gdTCR': '67.8', 'Memory CD4 T-cell Th1\\/Th17': '48.0', 'Memory CD4 T-cell Th17': '54.6', 'Memory CD4 T-cell Th2': '54.8', 'Non-Vd2 gdTCR': '73.7', 'Memory CD4 T-cell Th1': '58.8', 'Memory CD4 T-cell TFH': '61.9', 'Terminal effector memory CD4 T-cell': '72.8', 'Central memory CD8 T-cell': '59.9', 'Effector memory CD8 T-cell': '90.7', 'Terminal effector memory CD8 T-cell': '75.8', 'Non-switched memory B-cell': '52.6', 'Plasmablast': '62.3', 'Switched memory B-cell': '55.8', 'Exhausted memory B-cell': '52.1', 'Progenitor cell': '44.7', 'Memory T-reg': '82.4', 'Naive CD4 T-cell activated': '133.9', 'Naive CD8 T-cell activated': '163.4', 'Naive T-reg': '54.7'}
2IWG, 5JPX, 5OLM, 6FGA, 6S53, 7BBD, 8A58
{'Adipose Tissue': 21.42795099667774, 'Adrenal Gland': 16.707763565891472, 'Bladder': 21.861904761904764, 'Blood': 61.11958557588805, 'Blood Vessel': 22.62928389513109, 'Brain': 4.305000416351249, 'Breast': 20.001740740740743, 'Cervix Uteri': 26.420526315789473, 'Colon': 23.40817458279846, 'Esophagus': 21.74157577854671, 'Fallopian Tube': 25.39, 'Heart': 6.66628106852497, 'Kidney': 13.61479775280899, 'Liver': 10.388, 'Lung': 32.00464878892734, 'Muscle': 3.944284806973848, 'Nerve': 25.39305008077545, 'Ovary': 30.51811111111111, 'Pancreas': 6.808080182926829, 'Pituitary': 12.995699646643107, 'Prostate': 21.00597551020408, 'Salivary Gland': 16.434148148148147, 'Skin': 17.851811498065228, 'Small Intestine': 28.907085561497325, 'Spleen': 50.16024896265561, 'Stomach': 19.072721448467966, 'Testis': 6.377013850415512, 'Thyroid': 21.553307810107196, 'Uterus': 29.83549295774648, 'Vagina': 21.551141025641027}
SQSTM1
MASLTVKAYLLGKEDAAREIRRFSFCCSPEPEAEAEAAAGPGPCERLLSRVAALFPALRPGGFQAHYRDEDGDLVAFSSDEELTMAMSYVKDDIFRIYIKEKKECRRDHRPPCAQEAPRNMVHPNVICDGCNGPVVGTRYKCSVCPDYDLCSVCEGKGLHRGHTKLAFPSPFGHLSEGFSHSRWLRKVKHGHFGWPGWEMGPPGNWSPRPPRAGEARPGPTAESASGPSEDPSVNFLKNVGESVAAALSPLGIEVDIDVEHGGKRSRLTPVSPESSSTEEKSSSQPSSCCSDPSKPGGNVEGATQSLAEQMRKIALESEGRPEEQMESDNCSGGDDDWTHLSSKEVDPSTGELQSLQMPESEGPSSLDPSQEGPTGLKEAALYPHLPPEADPRLIESLSQMLSMGFSDEGGWLTRLLQTKNYDIGAALDTIQYSKHPPPL
Homo sapiens
Cytoplasmic vesicle, autophagosome, Preautophagosomal structure, Cytoplasm, cytosol, Nucleus, PML body, Late endosome, Lysosome, Nucleus, Endoplasmic reticulum, Cytoplasm, myofibril, sarcomere
Tissue enhanced (skeletal)
{'Ciliated cells': '254.9', 'Basal respiratory cells': '303.5', 'Club cells': '412.8', 'Ionocytes': '327.7', 'Mucus glandular cells': '545.4', 'Serous glandular cells': '241.1', 'Gastric mucus-secreting cells': '1156.1', 'Proximal enterocytes': '298.5', 'Paneth cells': '389.6', 'Distal enterocytes': '395.5', 'Intestinal goblet cells': '288.5', 'Exocrine glandular cells': '-0.553', 'Basal prostatic cells': '429.7', 'Prostatic glandular cells': '228.8', 'Breast glandular cells': '0.084', 'Breast myoepithelial cells': '0.100', 'Glandular and luminal cells': '559.1', 'Secretory cells': '266.7', 'Basal keratinocytes': '312.1', 'Suprabasal keratinocytes': '293.1', 'Basal squamous epithelial cells': '667.0', 'Squamous epithelial cells': '548.4', 'Alveolar cells type 1': '0.049', 'Alveolar cells type 2': '0.349', 'Salivary duct cells': '492.8', 'Ductal cells': '0.475', 'Hepatocytes': '0.458', 'Cholangiocytes': '299.5', 'Proximal tubular cells': '0.363', 'Distal tubular cells': '199.8', 'Collecting duct cells': '149.8', 'Mesothelial cells': '0.235', 'Sertoli cells': '0.501', 'Granulosa cells': '206.8', 'Enteroendocrine cells': '276.7', 'Pancreatic endocrine cells': '708.1', 'Leydig cells': '0.615', 'Excitatory neurons': '34.0', 'Inhibitory neurons': '35.6', 'Cone photoreceptor cells': '52.7', 'Rod photoreceptor cells': '66.0', 'Bipolar cells': '75.2', 'Horizontal cells': '66.1', 'Astrocytes': '35.0', 'Oligodendrocyte precursor cells': '15.6', 'Oligodendrocytes': '57.9', 'Microglial cells': '26.8', 'Muller glia cells': '140.9', 'Schwann cells': '0.000', 'Spermatogonia': '0.572', 'Spermatocytes': '0.178', 'Early spermatids': '-0.467', 'Late spermatids': '-0.596', 'Oocytes': '155.1', 'Cytotrophoblasts': '251.1', 'Syncytiotrophoblasts': '2518.9', 'Extravillous trophoblasts': '140.8', 'Endothelial cells': '266.9', 'Lymphatic endothelial cells': '277.6', 'Cardiomyocytes': '0.690', 'Skeletal myocytes': '-0.315', 'Smooth muscle cells': '271.4', 'Adipocytes': '375.3', 'Melanocytes': '-0.136', 'Fibroblasts': '407.1', 'Peritubular cells': '0.482', 'Endometrial stromal cells': '232.0', 'Ovarian stromal cells': '281.7', 'Undifferentiated cells': '142.4', 'T-cells': '238.5', 'B-cells': '255.1', 'Plasma cells': '481.3', 'Nk-cells': '241.5', 'Granulocytes': '709.7', 'Monocytes': '347.3', 'Macrophages': '391.1', 'Hofbauer cells': '276.8', 'Kupffer cells': '137.8', 'Dendritic cells': '178.7', 'Langerhans cells': '0.070', 'Erythroid cells': '-0.027', 'Adipocytes (Subcutaneous)': '0.147', 'Adipocytes (Visceral)': '-0.005', 'Breast glandular cells (progenitors)': '0.135', 'Adipocytes (Breast)': '-0.051', 'Colon enterocytes': '-0.073', 'Colon enteroendocrine cells': '0.157', 'Enteric glia cells': '-0.333', 'Mitotic cells (Colon)': '-0.049', 'Mitotic cells (Heart)': '0.414', 'Podocytes': '-0.044', 'Ascending Loop of Henle cells': '0.216', 'Intercalated cells': '-0.050', 'Cholangiocyte': '0.428', 'NK-cells (Liver)': '-0.358', 'Respiratory ciliated cells': '-0.133', 'Mitotic cells (Lung)': '0.079', 'NK-cells (Lung)': '-0.263', 'B-cells (Lung)': '-0.225', 'Alpha cells': '0.245', 'Beta cells': '0.081', 'Prostate glandular cells': '-0.065', 'Prostate basal glandular cells': '0.191', 'Urothelial cells': '0.064', 'Keratinocyte (other)': '-0.136', 'Keratinocyte (granular)': '-0.016', 'Hair cortex cells': '0.016', 'Inner root sheath cells': '0.014', 'Outer root sheath cells': '0.057', 'Sebaceous gland cells': '-0.005', 'Eccrine sweat gland cells': '0.190', 'Adipocytes (Skin)': '0.228', 'Mitotic cells (Skin)': '-0.025', 'Parietal cells': '-0.463', 'Chief cells': '-0.419', 'Gastric mucous cells': '-0.164', 'Gastric enteroendocrine cells': '-0.349', 'Mitotic cells (Stomach)': '0.114', 'Parafollicular cells': '0.106', 'Thyroid glandular cells': '0.349', 'Mitotic cells (Thyroid)': '-0.074', 'Adrenal cortex cells': '0.657', 'Adrenal medulla cells': '-0.038', 'Mitotic cells (Adrenal gland)': '0.490', 'Minor salivary glandular cells': '0.763', 'Minor salivary gland ductal cells': '0.010', 'Minor salivary gland basal cells': '0.055', 'Mitotic cells (Minor salivary gland)': '0.269', 'Adipocytes (Minor salivary gland)': '0.166', 'Somatotropes': '-0.163', 'Lactotropes': '-0.239', 'Gonadotropes': '-0.067', 'Corticotropes': '-0.191', 'Thyrotropes': '-0.068', 'Undifferentiated cells (Pituitary gland)': '0.342', 'Mitotic cells (Spleen)': '-0.273', 'Platelets': '-0.106', 'Erythrocytes': '-0.220', 'Hematopoietic stem cells': '-0.160', 'B-cells (Spleen)': '0.155', 'NK-cells (Spleen)': '0.050', 'Amygdala excitatory': '59.2', 'Cerebellar inhibitory': '65.2', 'Cge interneuron': '73.1', 'Deep-layer corticothalamic and 6b': '65.6', 'Deep-layer intratelencephalic': '71.3', 'Deep-layer near-projecting': '63.0', 'Eccentric medium spiny neuron': '53.8', 'Hippocampal ca1-3': '50.4', 'Hippocampal ca4': '62.1', 'Hippocampal dentate gyrus': '55.1', 'Lamp5-lhx6 and chandelier': '73.9', 'Lower rhombic lip': '65.1', 'Mammillary body': '74.2', 'Medium spiny neuron': '44.0', 'Mge interneuron': '67.8', 'Midbrain-derived inhibitory': '58.9', 'Miscellaneous': '69.0', 'Splatter': '67.3', 'Thalamic excitatory': '60.2', 'Upper rhombic lip': '98.7', 'Upper-layer intratelencephalic': '69.1', 'Astrocyte': '153.9', 'Bergmann glia': '71.1', 'Central nervous system macrophage': '86.5', 'Choroid plexus epithelial cell': '101.0', 'Committed oligodendrocyte precursor': '55.7', 'Ependymal cell': '80.1', 'Oligodendrocyte': '101.9', 'Oligodendrocyte precursor cell': '39.5', 'Endothelial cell': '278.0', 'Pericyte': '191.2', 'Vascular associated smooth muscle cell': '161.9', 'Fibroblast': '222.5', 'Leukocyte': '96.9', 'Basophil': '508.9', 'Eosinophil': '424.2', 'Neutrophil': '652.8', 'Classical monocyte': '47.8', 'Non-classical monocyte': '29.9', 'Intermediate monocyte': '356.0', 'T-reg': '142.5', 'GdT-cell': '195.4', 'MAIT T-cell': '215.6', 'Memory CD4 T-cell': '170.7', 'Naive CD4 T-cell': '16.2', 'Memory CD8 T-cell': '174.7', 'Naive CD8 T-cell': '21.4', 'Memory B-cell': '157.2', 'Naive B-cell': '25.8', 'Plasmacytoid DC': '115.9', 'Myeloid DC': '331.4', 'NK-cell': '36.1', 'Total PBMC': '257.2', 'Vd2 gdTCR': '223.7', 'Memory CD4 T-cell TFH': '40.8', 'Memory CD4 T-cell Th2': '31.0', 'Memory CD4 T-cell Th17': '32.4', 'Memory CD4 T-cell Th1\\/Th17': '28.7', 'Non-Vd2 gdTCR': '252.7', 'Memory CD4 T-cell Th1': '34.9', 'Terminal effector memory CD4 T-cell': '193.7', 'Central memory CD8 T-cell': '165.7', 'Effector memory CD8 T-cell': '183.8', 'Terminal effector memory CD8 T-cell': '202.0', 'Switched memory B-cell': '176.4', 'Plasmablast': '232.0', 'Non-switched memory B-cell': '141.3', 'Exhausted memory B-cell': '166.5', 'Progenitor cell': '129.8', 'Naive CD4 T-cell activated': '27.6', 'Naive CD8 T-cell activated': '47.1', 'Memory T-reg': '49.4', 'Naive T-reg': '25.3'}
1Q02, 2JY7, 2JY8, 2K0B, 2KNV, 4MJS, 4UF8, 4UF9, 5YP7, 5YP8, 5YPA, 5YPB, 5YPC, 5YPE, 5YPF, 5YPG, 5YPH, 6JM4, 6KHZ, 6MJ7, 6TGY, 6TH3, 7R1O
{'Adipose Tissue': 103.79857142857142, 'Adrenal Gland': 137.62174418604653, 'Bladder': 125.40238095238094, 'Blood': 40.866539289558666, 'Blood Vessel': 134.04116104868913, 'Brain': 37.39114193792581, 'Breast': 94.64023965141612, 'Cervix Uteri': 103.8763157894737, 'Colon': 71.5495892169448, 'Esophagus': 73.89315570934257, 'Fallopian Tube': 90.00555555555555, 'Heart': 45.45540301974448, 'Kidney': 49.14531460674157, 'Liver': 52.86030973451327, 'Lung': 102.5726124567474, 'Muscle': 180.5583312577833, 'Nerve': 93.75819063004846, 'Ovary': 96.6587777777778, 'Pancreas': 37.02713414634146, 'Pituitary': 64.30236749116608, 'Prostate': 73.32085714285715, 'Salivary Gland': 94.23123456790124, 'Skin': 81.7317965726921, 'Small Intestine': 61.07262032085561, 'Spleen': 55.89605809128631, 'Stomach': 72.66618384401114, 'Testis': 35.49343490304709, 'Thyroid': 129.193078101072, 'Uterus': 100.98084507042256, 'Vagina': 81.40307692307692}
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[53.35, 65.89, 77.79, 88.84, 93.53, 95.33, 95.58, 95.8, 96.25, 94.98, 94.26, 89.06, 85.27, 87.53, 86.35, 89.44, 90.27, 90.78, 93.07, 94.84, 94.19, 93.65, 93.93, 91.44, 89.51, 82.51, 72.17, 65.72, 59.14, 54.74, 50.94, 47.61, 50.47, 49.42, 48.47, 48.41, 50.0, 55.6, 60.39, 67.2, 81.47, 87.33, 90.22, 92.52, 91.89, 91.48, 92.63, 92.83, 91.28, 92.01, 93.73, 92.61, 91.66, 92.87, 91.6, 88.11, 84.77, 85.9, 85.43, 82.64, 80.73, 88.17, 92.86, 93.54, 95.31, 96.44, 96.06, 95.24, 94.8, 93.35, 94.09, 91.87, 95.03, 93.78, 96.05, 95.92, 95.17, 93.32, 93.73, 92.53, 92.49, 94.47, 92.81, 92.29, 92.15, 93.74, 90.8, 91.41, 92.17, 91.32, 88.78, 88.25, 88.36, 92.87, 94.51, 95.05, 96.0, 96.46, 95.37, 93.17, 90.72, 85.41, 74.13, 61.45, 42.44, 43.49, 44.58, 39.26, 38.86, 46.79, 40.42, 42.12, 35.39, 42.13, 41.96, 43.81, 51.8, 55.22, 60.15, 66.43, 80.27, 88.11, 86.96, 86.13, 87.51, 90.38, 93.62, 95.04, 94.7, 91.37, 93.44, 92.35, 89.74, 91.1, 92.07, 89.43, 87.93, 90.98, 92.67, 93.86, 93.13, 94.46, 91.24, 92.75, 91.67, 89.14, 88.62, 93.87, 94.09, 94.01, 93.59, 91.68, 92.69, 94.12, 93.15, 89.98, 91.17, 88.08, 85.87, 86.4, 86.4, 87.67, 90.73, 90.17, 92.01, 91.44, 91.86, 88.93, 84.21, 79.19, 72.13, 62.72, 52.05, 40.04, 42.42, 38.42, 37.36, 38.61, 39.71, 42.71, 48.08, 49.58, 53.16, 52.44, 54.69, 47.03, 52.29, 50.97, 43.69, 40.61, 38.97, 40.65, 34.85, 35.44, 41.0, 45.45, 36.5, 38.01, 40.21, 43.38, 41.16, 47.19, 45.79, 41.47, 40.07, 34.26, 37.46, 45.79, 43.53, 58.23, 42.92, 41.49, 41.73, 38.84, 37.43, 37.8, 34.8, 43.87, 36.75, 42.01, 35.52, 37.24, 32.72, 37.66, 37.76, 31.99, 33.34, 45.82, 48.61, 62.23, 72.92, 83.68, 82.55, 86.87, 86.98, 89.83, 90.17, 89.49, 89.86, 91.77, 90.05, 90.87, 91.04, 91.12, 91.53, 90.56, 92.09, 92.42, 87.92, 92.32, 90.81, 85.21, 87.34, 85.18, 85.03, 86.76, 86.19, 86.04, 83.97, 82.43, 74.8, 71.87, 72.89, 69.74, 71.29, 73.31, 72.59, 65.57, 59.92, 56.27, 48.65, 40.59, 41.53, 34.4, 36.5, 34.29, 37.78, 36.07, 40.15, 38.11, 39.16, 35.52, 38.51, 40.23, 43.8, 36.96, 43.84, 39.5, 29.98, 29.74, 40.41, 36.33, 43.45, 41.19, 42.12, 41.03, 32.65, 35.92, 38.55, 44.08, 35.96, 34.17, 41.67, 42.61, 42.37, 49.83, 48.76, 47.15, 51.21, 51.96, 52.95, 55.42, 47.53, 45.08, 38.43, 37.42, 41.69, 42.05, 34.48, 39.04, 32.26, 38.29, 31.09, 35.92, 30.08, 35.67, 34.91, 33.18, 39.63, 35.75, 39.77, 37.98, 42.68, 36.62, 42.68, 41.23, 47.59, 59.33, 59.76, 46.36, 43.04, 43.31, 47.19, 47.02, 50.65, 53.67, 44.51, 48.8, 49.79, 56.16, 51.13, 57.36, 46.89, 41.88, 44.66, 41.32, 38.77, 40.81, 46.89, 36.67, 42.97, 42.32, 38.14, 41.13, 33.88, 34.86, 39.21, 30.23, 38.4, 36.53, 43.71, 36.85, 36.72, 45.42, 48.9, 52.62, 52.13, 53.41, 52.84, 50.5, 53.1, 59.17, 56.87, 61.37, 59.24, 58.97, 59.19, 59.12, 61.52, 66.39, 80.22, 84.78, 87.49, 90.43, 88.22, 90.4, 92.93, 92.73, 90.87, 92.24, 92.1, 91.46, 91.02, 88.89, 89.99, 90.61, 88.81, 88.82, 83.27, 85.85, 87.96, 90.29, 91.36, 91.17, 90.32, 92.12, 93.48, 91.8, 91.39, 92.23, 89.51, 90.41, 92.71, 91.36, 92.49, 91.39, 92.41, 92.35, 90.15, 88.67, 86.25, 78.79, 65.51, 60.25, 59.21, 54.33, 51.18, 56.34, 63.88, 49.86]
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RING finger
Component of a SCF(SKP2)-like complex containing CUL1, SKP1, TRIM21 and SKP2.
SCF
null
IRF8, CALR, CUL1, FBXW11, HSPA5, IKBKB, IRF3, SKP1 , VCP,SKP2, DCP2 ,ULK1, BECN1,GABARAP, GABARAPL1, GABARAPL2 , MAP1LC3C,SQSTM1,IRF3 , NMI, IFI35 , CUL1, TRIM21
USP4, IKBKB, TRIM21, CDKN1B, IRF3, IRF8, MNI
mono, 63
null
UBE2D2, UBE2D1, UBE2E1, UBE2E2
Homotrimer
null
90.718042
0.406716
67.094841
0.643591
1,803
P19474
Q14653
18641315, 19494276, E3NethUbiquitome
UbiNet, UbiBrowser, 31181401
TRIM21
MASAARLTMMWEEVTCPICLDPFVEPVSIECGHSFCQECISQVGKGGGSVCPVCRQRFLLKNLRPNRQLANMVNNLKEISQEAREGTQGERCAVHGERLHLFCEKDGKALCWVCAQSRKHRDHAMVPLEEAAQEYQEKLQVALGELRRKQELAEKLEVEIAIKRADWKKTVETQKSRIHAEFVQQKNFLVEEEQRQLQELEKDEREQLRILGEKEAKLAQQSQALQELISELDRRCHSSALELLQEVIIVLERSESWNLKDLDITSPELRSVCHVPGLKKMLRTCAVHITLDPDTANPWLILSEDRRQVRLGDTQQSIPGNEERFDSYPMVLGAQHFHSGKHYWEVDVTGKEAWDLGVCRDSVRRKGHFLLSSKSGFWTIWLWNKQKYEAGTYPQTPLHLQVPPCQVGIFLDYEAGMVSFYNITDHGSLIYSFSECAFTGPLRPFFSPGFNDGGKNTAPLTLCPLNIGSQGSTDY
Homo sapiens
Cytoplasm, Cytoplasmic vesicle, autophagosome, Nucleus, Cytoplasm, P-body, Cytoplasm, Stress granule
Low tissue specificity
{'Ciliated cells': '3.8', 'Basal respiratory cells': '6.8', 'Club cells': '5.8', 'Ionocytes': '3.7', 'Mucus glandular cells': '4.8', 'Serous glandular cells': '2.3', 'Gastric mucus-secreting cells': '8.8', 'Proximal enterocytes': '8.9', 'Paneth cells': '3.9', 'Distal enterocytes': '8.5', 'Intestinal goblet cells': '8.4', 'Exocrine glandular cells': '-0.716', 'Basal prostatic cells': '5.4', 'Prostatic glandular cells': '5.0', 'Breast glandular cells': '0.298', 'Breast myoepithelial cells': '0.351', 'Glandular and luminal cells': '5.9', 'Secretory cells': '8.4', 'Basal keratinocytes': '3.2', 'Suprabasal keratinocytes': '2.7', 'Basal squamous epithelial cells': '6.4', 'Squamous epithelial cells': '4.3', 'Alveolar cells type 1': '0.116', 'Alveolar cells type 2': '0.115', 'Salivary duct cells': '3.0', 'Ductal cells': '0.700', 'Hepatocytes': '0.503', 'Cholangiocytes': '11.4', 'Proximal tubular cells': '0.175', 'Distal tubular cells': '0.0', 'Collecting duct cells': '5.8', 'Mesothelial cells': '0.451', 'Sertoli cells': '0.479', 'Granulosa cells': '4.8', 'Enteroendocrine cells': '3.7', 'Pancreatic endocrine cells': '3.4', 'Leydig cells': '0.632', 'Excitatory neurons': '0.2', 'Inhibitory neurons': '0.1', 'Cone photoreceptor cells': '0.0', 'Rod photoreceptor cells': '0.0', 'Bipolar cells': '0.7', 'Horizontal cells': '0.6', 'Astrocytes': '0.0', 'Oligodendrocyte precursor cells': '0.9', 'Oligodendrocytes': '0.1', 'Microglial cells': '1.8', 'Muller glia cells': '2.4', 'Schwann cells': '0.099', 'Spermatogonia': '0.401', 'Spermatocytes': '-0.062', 'Early spermatids': '-0.578', 'Late spermatids': '-0.618', 'Oocytes': '1.5', 'Cytotrophoblasts': '6.6', 'Syncytiotrophoblasts': '9.8', 'Extravillous trophoblasts': '10.0', 'Endothelial cells': '7.8', 'Lymphatic endothelial cells': '6.9', 'Cardiomyocytes': '0.335', 'Skeletal myocytes': '-0.080', 'Smooth muscle cells': '6.3', 'Adipocytes': '8.3', 'Melanocytes': '0.101', 'Fibroblasts': '6.5', 'Peritubular cells': '0.579', 'Endometrial stromal cells': '4.5', 'Ovarian stromal cells': '6.7', 'Undifferentiated cells': '5.9', 'T-cells': '9.9', 'B-cells': '8.8', 'Plasma cells': '5.0', 'Nk-cells': '15.1', 'Granulocytes': '6.2', 'Monocytes': '7.8', 'Macrophages': '8.5', 'Hofbauer cells': '9.9', 'Kupffer cells': '10.3', 'Dendritic cells': '8.0', 'Langerhans cells': '0.466', 'Erythroid cells': '-0.084', 'Adipocytes (Subcutaneous)': '-0.368', 'Adipocytes (Visceral)': '-0.167', 'Breast glandular cells (progenitors)': '0.190', 'Adipocytes (Breast)': '-0.382', 'Colon enterocytes': '0.004', 'Colon enteroendocrine cells': '0.196', 'Enteric glia cells': '-0.129', 'Mitotic cells (Colon)': '0.005', 'Mitotic cells (Heart)': '0.486', 'Podocytes': '-0.114', 'Ascending Loop of Henle cells': '0.371', 'Intercalated cells': '-0.097', 'Cholangiocyte': '0.375', 'NK-cells (Liver)': '-0.278', 'Respiratory ciliated cells': '-0.022', 'Mitotic cells (Lung)': '0.157', 'NK-cells (Lung)': '0.110', 'B-cells (Lung)': '-0.155', 'Alpha cells': '0.333', 'Beta cells': '0.161', 'Prostate glandular cells': '-0.162', 'Prostate basal glandular cells': '0.286', 'Urothelial cells': '0.283', 'Keratinocyte (other)': '0.121', 'Keratinocyte (granular)': '-0.008', 'Hair cortex cells': '-0.113', 'Inner root sheath cells': '-0.069', 'Outer root sheath cells': '0.125', 'Sebaceous gland cells': '0.110', 'Eccrine sweat gland cells': '0.070', 'Adipocytes (Skin)': '0.019', 'Mitotic cells (Skin)': '0.236', 'Parietal cells': '-0.609', 'Chief cells': '-0.599', 'Gastric mucous cells': '-0.193', 'Gastric enteroendocrine cells': '-0.441', 'Mitotic cells (Stomach)': '0.261', 'Parafollicular cells': '-0.028', 'Thyroid glandular cells': '0.094', 'Mitotic cells (Thyroid)': '0.242', 'Adrenal cortex cells': '0.619', 'Adrenal medulla cells': '0.063', 'Mitotic cells (Adrenal gland)': '0.483', 'Minor salivary glandular cells': '0.582', 'Minor salivary gland ductal cells': '0.072', 'Minor salivary gland basal cells': '0.229', 'Mitotic cells (Minor salivary gland)': '0.376', 'Adipocytes (Minor salivary gland)': '0.211', 'Somatotropes': '-0.121', 'Lactotropes': '-0.287', 'Gonadotropes': '0.004', 'Corticotropes': '-0.352', 'Thyrotropes': '-0.054', 'Undifferentiated cells (Pituitary gland)': '0.486', 'Mitotic cells (Spleen)': '-0.016', 'Platelets': '0.115', 'Erythrocytes': '0.098', 'Hematopoietic stem cells': '0.042', 'B-cells (Spleen)': '0.028', 'NK-cells (Spleen)': '0.157', 'Amygdala excitatory': '0.1', 'Cerebellar inhibitory': '0.2', 'Cge interneuron': '0.3', 'Deep-layer corticothalamic and 6b': '0.3', 'Deep-layer intratelencephalic': '0.1', 'Deep-layer near-projecting': '0.1', 'Eccentric medium spiny neuron': '0.4', 'Hippocampal ca1-3': '0.5', 'Hippocampal ca4': '0.1', 'Hippocampal dentate gyrus': '0.3', 'Lamp5-lhx6 and chandelier': '0.3', 'Lower rhombic lip': '0.2', 'Mammillary body': '0.4', 'Medium spiny neuron': '0.6', 'Mge interneuron': '0.1', 'Midbrain-derived inhibitory': '0.6', 'Miscellaneous': '0.6', 'Splatter': '0.5', 'Thalamic excitatory': '1.3', 'Upper rhombic lip': '0.1', 'Upper-layer intratelencephalic': '0.1', 'Astrocyte': '1.5', 'Bergmann glia': '1.5', 'Central nervous system macrophage': '6.0', 'Choroid plexus epithelial cell': '2.9', 'Committed oligodendrocyte precursor': '1.0', 'Ependymal cell': '1.3', 'Oligodendrocyte': '0.1', 'Oligodendrocyte precursor cell': '2.3', 'Endothelial cell': '6.4', 'Pericyte': '5.3', 'Vascular associated smooth muscle cell': '3.1', 'Fibroblast': '5.3', 'Leukocyte': '7.4', 'Basophil': '107.0', 'Eosinophil': '312.5', 'Neutrophil': '496.9', 'Classical monocyte': '25.8', 'Non-classical monocyte': '66.1', 'Intermediate monocyte': '117.0', 'T-reg': '72.1', 'GdT-cell': '89.5', 'MAIT T-cell': '61.2', 'Memory CD4 T-cell': '76.8', 'Naive CD4 T-cell': '47.0', 'Memory CD8 T-cell': '81.1', 'Naive CD8 T-cell': '43.5', 'Memory B-cell': '50.4', 'Naive B-cell': '38.5', 'Plasmacytoid DC': '47.5', 'Myeloid DC': '92.2', 'NK-cell': '88.9', 'Total PBMC': '83.8', 'Vd2 gdTCR': '67.8', 'Memory CD4 T-cell Th1\\/Th17': '48.0', 'Memory CD4 T-cell Th17': '54.6', 'Memory CD4 T-cell Th2': '54.8', 'Non-Vd2 gdTCR': '73.7', 'Memory CD4 T-cell Th1': '58.8', 'Memory CD4 T-cell TFH': '61.9', 'Terminal effector memory CD4 T-cell': '72.8', 'Central memory CD8 T-cell': '59.9', 'Effector memory CD8 T-cell': '90.7', 'Terminal effector memory CD8 T-cell': '75.8', 'Non-switched memory B-cell': '52.6', 'Plasmablast': '62.3', 'Switched memory B-cell': '55.8', 'Exhausted memory B-cell': '52.1', 'Progenitor cell': '44.7', 'Memory T-reg': '82.4', 'Naive CD4 T-cell activated': '133.9', 'Naive CD8 T-cell activated': '163.4', 'Naive T-reg': '54.7'}
2IWG, 5JPX, 5OLM, 6FGA, 6S53, 7BBD, 8A58
{'Adipose Tissue': 21.42795099667774, 'Adrenal Gland': 16.707763565891472, 'Bladder': 21.861904761904764, 'Blood': 61.11958557588805, 'Blood Vessel': 22.62928389513109, 'Brain': 4.305000416351249, 'Breast': 20.001740740740743, 'Cervix Uteri': 26.420526315789473, 'Colon': 23.40817458279846, 'Esophagus': 21.74157577854671, 'Fallopian Tube': 25.39, 'Heart': 6.66628106852497, 'Kidney': 13.61479775280899, 'Liver': 10.388, 'Lung': 32.00464878892734, 'Muscle': 3.944284806973848, 'Nerve': 25.39305008077545, 'Ovary': 30.51811111111111, 'Pancreas': 6.808080182926829, 'Pituitary': 12.995699646643107, 'Prostate': 21.00597551020408, 'Salivary Gland': 16.434148148148147, 'Skin': 17.851811498065228, 'Small Intestine': 28.907085561497325, 'Spleen': 50.16024896265561, 'Stomach': 19.072721448467966, 'Testis': 6.377013850415512, 'Thyroid': 21.553307810107196, 'Uterus': 29.83549295774648, 'Vagina': 21.551141025641027}
IRF3
MGTPKPRILPWLVSQLDLGQLEGVAWVNKSRTRFRIPWKHGLRQDAQQEDFGIFQAWAEATGAYVPGRDKPDLPTWKRNFRSALNRKEGLRLAEDRSKDPHDPHKIYEFVNSGVGDFSQPDTSPDTNGGGSTSDTQEDILDELLGNMVLAPLPDPGPPSLAVAPEPCPQPLRSPSLDNPTPFPNLGPSENPLKRLLVPGEEWEFEVTAFYRGRQVFQQTISCPEGLRLVGSEVGDRTLPGWPVTLPDPGMSLTDRGVMSYVRHVLSCLGGGLALWRAGQWLWAQRLGHCHTYWAVSEELLPNSGHGPDGEVPKDKEGGVFDLGPFIVDLITFTEGSGRSPRYALWFCVGESWPQDQPWTKRLVMVKVVPTCLRALVEMARVGGASSLENTVDLHISNSHPLSLTSDQYKAYLQDLVEGMDFQGPGES
Homo sapiens
Cytoplasm, Nucleus, Mitochondrion
Low tissue specificity
{'Ciliated cells': '43.9', 'Basal respiratory cells': '55.3', 'Club cells': '46.8', 'Ionocytes': '62.2', 'Mucus glandular cells': '34.1', 'Serous glandular cells': '40.7', 'Gastric mucus-secreting cells': '65.4', 'Proximal enterocytes': '65.5', 'Paneth cells': '52.7', 'Distal enterocytes': '66.8', 'Intestinal goblet cells': '63.5', 'Exocrine glandular cells': '-0.649', 'Basal prostatic cells': '54.1', 'Prostatic glandular cells': '40.6', 'Breast glandular cells': '0.683', 'Breast myoepithelial cells': '0.619', 'Glandular and luminal cells': '35.6', 'Secretory cells': '40.5', 'Basal keratinocytes': '45.8', 'Suprabasal keratinocytes': '41.4', 'Basal squamous epithelial cells': '24.4', 'Squamous epithelial cells': '21.5', 'Alveolar cells type 1': '0.023', 'Alveolar cells type 2': '-0.529', 'Salivary duct cells': '43.2', 'Ductal cells': '0.497', 'Hepatocytes': '0.088', 'Cholangiocytes': '36.2', 'Proximal tubular cells': '0.161', 'Distal tubular cells': '27.7', 'Collecting duct cells': '35.0', 'Mesothelial cells': '0.454', 'Sertoli cells': '0.250', 'Granulosa cells': '34.9', 'Enteroendocrine cells': '43.5', 'Pancreatic endocrine cells': '40.8', 'Leydig cells': '0.343', 'Excitatory neurons': '3.8', 'Inhibitory neurons': '5.4', 'Cone photoreceptor cells': '22.1', 'Rod photoreceptor cells': '43.1', 'Bipolar cells': '30.2', 'Horizontal cells': '22.7', 'Astrocytes': '15.2', 'Oligodendrocyte precursor cells': '6.6', 'Oligodendrocytes': '10.0', 'Microglial cells': '9.8', 'Muller glia cells': '31.8', 'Schwann cells': '0.062', 'Spermatogonia': '0.105', 'Spermatocytes': '-0.098', 'Early spermatids': '-0.434', 'Late spermatids': '-0.414', 'Oocytes': '17.6', 'Cytotrophoblasts': '80.3', 'Syncytiotrophoblasts': '49.9', 'Extravillous trophoblasts': '100.9', 'Endothelial cells': '36.2', 'Lymphatic endothelial cells': '55.3', 'Cardiomyocytes': '0.279', 'Skeletal myocytes': '0.005', 'Smooth muscle cells': '32.2', 'Adipocytes': '40.9', 'Melanocytes': '-0.153', 'Fibroblasts': '31.8', 'Peritubular cells': '0.352', 'Endometrial stromal cells': '29.0', 'Ovarian stromal cells': '57.8', 'Undifferentiated cells': '46.1', 'T-cells': '66.3', 'B-cells': '46.6', 'Plasma cells': '65.3', 'Nk-cells': '86.5', 'Granulocytes': '46.1', 'Monocytes': '26.7', 'Macrophages': '36.6', 'Hofbauer cells': '44.4', 'Kupffer cells': '28.2', 'Dendritic cells': '31.5', 'Langerhans cells': '0.146', 'Erythroid cells': '0.064', 'Adipocytes (Subcutaneous)': '-0.472', 'Adipocytes (Visceral)': '-0.455', 'Breast glandular cells (progenitors)': '0.478', 'Adipocytes (Breast)': '-0.644', 'Colon enterocytes': '0.005', 'Colon enteroendocrine cells': '0.078', 'Enteric glia cells': '0.448', 'Mitotic cells (Colon)': '0.065', 'Mitotic cells (Heart)': '0.363', 'Podocytes': '-0.059', 'Ascending Loop of Henle cells': '0.364', 'Intercalated cells': '-0.054', 'Cholangiocyte': '0.276', 'NK-cells (Liver)': '-0.053', 'Respiratory ciliated cells': '0.184', 'Mitotic cells (Lung)': '-0.143', 'NK-cells (Lung)': '0.379', 'B-cells (Lung)': '0.295', 'Alpha cells': '0.388', 'Beta cells': '0.274', 'Prostate glandular cells': '0.129', 'Prostate basal glandular cells': '0.442', 'Urothelial cells': '0.418', 'Keratinocyte (other)': '0.084', 'Keratinocyte (granular)': '-0.184', 'Hair cortex cells': '-0.141', 'Inner root sheath cells': '-0.173', 'Outer root sheath cells': '0.104', 'Sebaceous gland cells': '-0.134', 'Eccrine sweat gland cells': '-0.117', 'Adipocytes (Skin)': '-0.211', 'Mitotic cells (Skin)': '-0.020', 'Parietal cells': '-0.009', 'Chief cells': '0.089', 'Gastric mucous cells': '0.305', 'Gastric enteroendocrine cells': '0.259', 'Mitotic cells (Stomach)': '0.230', 'Parafollicular cells': '0.002', 'Thyroid glandular cells': '-0.069', 'Mitotic cells (Thyroid)': '0.067', 'Adrenal cortex cells': '0.246', 'Adrenal medulla cells': '-0.103', 'Mitotic cells (Adrenal gland)': '-0.103', 'Minor salivary glandular cells': '0.522', 'Minor salivary gland ductal cells': '0.324', 'Minor salivary gland basal cells': '0.021', 'Mitotic cells (Minor salivary gland)': '0.021', 'Adipocytes (Minor salivary gland)': '0.116', 'Somatotropes': '0.106', 'Lactotropes': '-0.220', 'Gonadotropes': '-0.131', 'Corticotropes': '-0.254', 'Thyrotropes': '-0.063', 'Undifferentiated cells (Pituitary gland)': '0.226', 'Mitotic cells (Spleen)': '-0.363', 'Platelets': '-0.287', 'Erythrocytes': '-0.078', 'Hematopoietic stem cells': '-0.347', 'B-cells (Spleen)': '0.460', 'NK-cells (Spleen)': '0.365', 'Amygdala excitatory': '4.6', 'Cerebellar inhibitory': '11.3', 'Cge interneuron': '11.9', 'Deep-layer corticothalamic and 6b': '5.7', 'Deep-layer intratelencephalic': '5.8', 'Deep-layer near-projecting': '6.7', 'Eccentric medium spiny neuron': '5.4', 'Hippocampal ca1-3': '3.8', 'Hippocampal ca4': '3.9', 'Hippocampal dentate gyrus': '2.8', 'Lamp5-lhx6 and chandelier': '10.4', 'Lower rhombic lip': '12.9', 'Mammillary body': '6.1', 'Medium spiny neuron': '4.9', 'Mge interneuron': '7.2', 'Midbrain-derived inhibitory': '13.3', 'Miscellaneous': '6.4', 'Splatter': '10.0', 'Thalamic excitatory': '8.8', 'Upper rhombic lip': '12.1', 'Upper-layer intratelencephalic': '6.6', 'Astrocyte': '27.8', 'Bergmann glia': '15.7', 'Central nervous system macrophage': '44.3', 'Choroid plexus epithelial cell': '20.2', 'Committed oligodendrocyte precursor': '14.4', 'Ependymal cell': '28.2', 'Oligodendrocyte': '17.3', 'Oligodendrocyte precursor cell': '11.3', 'Endothelial cell': '26.5', 'Pericyte': '21.8', 'Vascular associated smooth muscle cell': '26.4', 'Fibroblast': '22.8', 'Leukocyte': '57.6', 'Basophil': '33.6', 'Eosinophil': '50.3', 'Neutrophil': '40.5', 'Classical monocyte': '37.1', 'Non-classical monocyte': '45.4', 'Intermediate monocyte': '48.9', 'T-reg': '74.2', 'GdT-cell': '58.7', 'MAIT T-cell': '68.6', 'Memory CD4 T-cell': '57.3', 'Naive CD4 T-cell': '99.6', 'Memory CD8 T-cell': '55.0', 'Naive CD8 T-cell': '118.2', 'Memory B-cell': '38.0', 'Naive B-cell': '66.0', 'Plasmacytoid DC': '59.7', 'Myeloid DC': '44.5', 'NK-cell': '108.2', 'Total PBMC': '65.5', 'Vd2 gdTCR': '81.5', 'Memory CD4 T-cell Th1\\/Th17': '96.3', 'Memory CD4 T-cell Th17': '129.2', 'Memory CD4 T-cell Th2': '134.0', 'Non-Vd2 gdTCR': '76.3', 'Memory CD4 T-cell Th1': '151.8', 'Memory CD4 T-cell TFH': '206.0', 'Terminal effector memory CD4 T-cell': '60.2', 'Central memory CD8 T-cell': '70.4', 'Effector memory CD8 T-cell': '77.3', 'Terminal effector memory CD8 T-cell': '74.2', 'Non-switched memory B-cell': '62.1', 'Plasmablast': '85.6', 'Switched memory B-cell': '72.1', 'Exhausted memory B-cell': '54.2', 'Progenitor cell': '32.7', 'Memory T-reg': '196.2', 'Naive CD4 T-cell activated': '30.1', 'Naive CD8 T-cell activated': '35.5', 'Naive T-reg': '143.2'}
1J2F, 1QWT, 1T2K, 1ZOQ, 2O61, 2O6G, 2PI0, 3A77, 3QU6, 5JEJ, 5JEK, 5JEL, 5JEM, 5JEO, 5JER, 6SIV, 6SJA, 7JFL
{'Adipose Tissue': 60.25851328903654, 'Adrenal Gland': 55.287093023255814, 'Bladder': 86.76380952380953, 'Blood': 60.55337136706136, 'Blood Vessel': 65.50230711610487, 'Brain': 23.22155791067373, 'Breast': 75.52657952069715, 'Cervix Uteri': 124.08842105263156, 'Colon': 65.76006418485237, 'Esophagus': 58.32807612456748, 'Fallopian Tube': 121.9211111111111, 'Heart': 22.934164924506387, 'Kidney': 57.9308988764045, 'Liver': 34.18556637168142, 'Lung': 95.55429065743944, 'Muscle': 12.952728518057285, 'Nerve': 84.41426494345718, 'Ovary': 102.69733333333332, 'Pancreas': 37.93832317073171, 'Pituitary': 88.49335689045937, 'Prostate': 123.69440816326532, 'Salivary Gland': 66.7258024691358, 'Skin': 67.6228634604754, 'Small Intestine': 108.03545454545456, 'Spleen': 149.03311203319504, 'Stomach': 60.546991643454035, 'Testis': 51.150000000000006, 'Thyroid': 130.00036753445636, 'Uterus': 110.2725352112676, 'Vagina': 97.41980769230769}
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RING finger
Component of a SCF(SKP2)-like complex containing CUL1, SKP1, TRIM21 and SKP2.
SCF
null
IRF8, CALR, CUL1, FBXW11, HSPA5, IKBKB, IRF3, SKP1 , VCP,SKP2, DCP2 ,ULK1, BECN1,GABARAP, GABARAPL1, GABARAPL2 , MAP1LC3C,SQSTM1,IRF3 , NMI, IFI35 , CUL1, TRIM21
USP4, IKBKB, TRIM21, CDKN1B, IRF3, IRF8, MNI
mono, 63
null
UBE2D2, UBE2D1, UBE2E1, UBE2E2
Homotrimer
null
90.718042
0.406716
79.871358
0.426393
1,856
P19474
Q16666
33061806
UbiBrowser
TRIM21
MASAARLTMMWEEVTCPICLDPFVEPVSIECGHSFCQECISQVGKGGGSVCPVCRQRFLLKNLRPNRQLANMVNNLKEISQEAREGTQGERCAVHGERLHLFCEKDGKALCWVCAQSRKHRDHAMVPLEEAAQEYQEKLQVALGELRRKQELAEKLEVEIAIKRADWKKTVETQKSRIHAEFVQQKNFLVEEEQRQLQELEKDEREQLRILGEKEAKLAQQSQALQELISELDRRCHSSALELLQEVIIVLERSESWNLKDLDITSPELRSVCHVPGLKKMLRTCAVHITLDPDTANPWLILSEDRRQVRLGDTQQSIPGNEERFDSYPMVLGAQHFHSGKHYWEVDVTGKEAWDLGVCRDSVRRKGHFLLSSKSGFWTIWLWNKQKYEAGTYPQTPLHLQVPPCQVGIFLDYEAGMVSFYNITDHGSLIYSFSECAFTGPLRPFFSPGFNDGGKNTAPLTLCPLNIGSQGSTDY
Homo sapiens
Cytoplasm, Cytoplasmic vesicle, autophagosome, Nucleus, Cytoplasm, P-body, Cytoplasm, Stress granule
Low tissue specificity
{'Ciliated cells': '3.8', 'Basal respiratory cells': '6.8', 'Club cells': '5.8', 'Ionocytes': '3.7', 'Mucus glandular cells': '4.8', 'Serous glandular cells': '2.3', 'Gastric mucus-secreting cells': '8.8', 'Proximal enterocytes': '8.9', 'Paneth cells': '3.9', 'Distal enterocytes': '8.5', 'Intestinal goblet cells': '8.4', 'Exocrine glandular cells': '-0.716', 'Basal prostatic cells': '5.4', 'Prostatic glandular cells': '5.0', 'Breast glandular cells': '0.298', 'Breast myoepithelial cells': '0.351', 'Glandular and luminal cells': '5.9', 'Secretory cells': '8.4', 'Basal keratinocytes': '3.2', 'Suprabasal keratinocytes': '2.7', 'Basal squamous epithelial cells': '6.4', 'Squamous epithelial cells': '4.3', 'Alveolar cells type 1': '0.116', 'Alveolar cells type 2': '0.115', 'Salivary duct cells': '3.0', 'Ductal cells': '0.700', 'Hepatocytes': '0.503', 'Cholangiocytes': '11.4', 'Proximal tubular cells': '0.175', 'Distal tubular cells': '0.0', 'Collecting duct cells': '5.8', 'Mesothelial cells': '0.451', 'Sertoli cells': '0.479', 'Granulosa cells': '4.8', 'Enteroendocrine cells': '3.7', 'Pancreatic endocrine cells': '3.4', 'Leydig cells': '0.632', 'Excitatory neurons': '0.2', 'Inhibitory neurons': '0.1', 'Cone photoreceptor cells': '0.0', 'Rod photoreceptor cells': '0.0', 'Bipolar cells': '0.7', 'Horizontal cells': '0.6', 'Astrocytes': '0.0', 'Oligodendrocyte precursor cells': '0.9', 'Oligodendrocytes': '0.1', 'Microglial cells': '1.8', 'Muller glia cells': '2.4', 'Schwann cells': '0.099', 'Spermatogonia': '0.401', 'Spermatocytes': '-0.062', 'Early spermatids': '-0.578', 'Late spermatids': '-0.618', 'Oocytes': '1.5', 'Cytotrophoblasts': '6.6', 'Syncytiotrophoblasts': '9.8', 'Extravillous trophoblasts': '10.0', 'Endothelial cells': '7.8', 'Lymphatic endothelial cells': '6.9', 'Cardiomyocytes': '0.335', 'Skeletal myocytes': '-0.080', 'Smooth muscle cells': '6.3', 'Adipocytes': '8.3', 'Melanocytes': '0.101', 'Fibroblasts': '6.5', 'Peritubular cells': '0.579', 'Endometrial stromal cells': '4.5', 'Ovarian stromal cells': '6.7', 'Undifferentiated cells': '5.9', 'T-cells': '9.9', 'B-cells': '8.8', 'Plasma cells': '5.0', 'Nk-cells': '15.1', 'Granulocytes': '6.2', 'Monocytes': '7.8', 'Macrophages': '8.5', 'Hofbauer cells': '9.9', 'Kupffer cells': '10.3', 'Dendritic cells': '8.0', 'Langerhans cells': '0.466', 'Erythroid cells': '-0.084', 'Adipocytes (Subcutaneous)': '-0.368', 'Adipocytes (Visceral)': '-0.167', 'Breast glandular cells (progenitors)': '0.190', 'Adipocytes (Breast)': '-0.382', 'Colon enterocytes': '0.004', 'Colon enteroendocrine cells': '0.196', 'Enteric glia cells': '-0.129', 'Mitotic cells (Colon)': '0.005', 'Mitotic cells (Heart)': '0.486', 'Podocytes': '-0.114', 'Ascending Loop of Henle cells': '0.371', 'Intercalated cells': '-0.097', 'Cholangiocyte': '0.375', 'NK-cells (Liver)': '-0.278', 'Respiratory ciliated cells': '-0.022', 'Mitotic cells (Lung)': '0.157', 'NK-cells (Lung)': '0.110', 'B-cells (Lung)': '-0.155', 'Alpha cells': '0.333', 'Beta cells': '0.161', 'Prostate glandular cells': '-0.162', 'Prostate basal glandular cells': '0.286', 'Urothelial cells': '0.283', 'Keratinocyte (other)': '0.121', 'Keratinocyte (granular)': '-0.008', 'Hair cortex cells': '-0.113', 'Inner root sheath cells': '-0.069', 'Outer root sheath cells': '0.125', 'Sebaceous gland cells': '0.110', 'Eccrine sweat gland cells': '0.070', 'Adipocytes (Skin)': '0.019', 'Mitotic cells (Skin)': '0.236', 'Parietal cells': '-0.609', 'Chief cells': '-0.599', 'Gastric mucous cells': '-0.193', 'Gastric enteroendocrine cells': '-0.441', 'Mitotic cells (Stomach)': '0.261', 'Parafollicular cells': '-0.028', 'Thyroid glandular cells': '0.094', 'Mitotic cells (Thyroid)': '0.242', 'Adrenal cortex cells': '0.619', 'Adrenal medulla cells': '0.063', 'Mitotic cells (Adrenal gland)': '0.483', 'Minor salivary glandular cells': '0.582', 'Minor salivary gland ductal cells': '0.072', 'Minor salivary gland basal cells': '0.229', 'Mitotic cells (Minor salivary gland)': '0.376', 'Adipocytes (Minor salivary gland)': '0.211', 'Somatotropes': '-0.121', 'Lactotropes': '-0.287', 'Gonadotropes': '0.004', 'Corticotropes': '-0.352', 'Thyrotropes': '-0.054', 'Undifferentiated cells (Pituitary gland)': '0.486', 'Mitotic cells (Spleen)': '-0.016', 'Platelets': '0.115', 'Erythrocytes': '0.098', 'Hematopoietic stem cells': '0.042', 'B-cells (Spleen)': '0.028', 'NK-cells (Spleen)': '0.157', 'Amygdala excitatory': '0.1', 'Cerebellar inhibitory': '0.2', 'Cge interneuron': '0.3', 'Deep-layer corticothalamic and 6b': '0.3', 'Deep-layer intratelencephalic': '0.1', 'Deep-layer near-projecting': '0.1', 'Eccentric medium spiny neuron': '0.4', 'Hippocampal ca1-3': '0.5', 'Hippocampal ca4': '0.1', 'Hippocampal dentate gyrus': '0.3', 'Lamp5-lhx6 and chandelier': '0.3', 'Lower rhombic lip': '0.2', 'Mammillary body': '0.4', 'Medium spiny neuron': '0.6', 'Mge interneuron': '0.1', 'Midbrain-derived inhibitory': '0.6', 'Miscellaneous': '0.6', 'Splatter': '0.5', 'Thalamic excitatory': '1.3', 'Upper rhombic lip': '0.1', 'Upper-layer intratelencephalic': '0.1', 'Astrocyte': '1.5', 'Bergmann glia': '1.5', 'Central nervous system macrophage': '6.0', 'Choroid plexus epithelial cell': '2.9', 'Committed oligodendrocyte precursor': '1.0', 'Ependymal cell': '1.3', 'Oligodendrocyte': '0.1', 'Oligodendrocyte precursor cell': '2.3', 'Endothelial cell': '6.4', 'Pericyte': '5.3', 'Vascular associated smooth muscle cell': '3.1', 'Fibroblast': '5.3', 'Leukocyte': '7.4', 'Basophil': '107.0', 'Eosinophil': '312.5', 'Neutrophil': '496.9', 'Classical monocyte': '25.8', 'Non-classical monocyte': '66.1', 'Intermediate monocyte': '117.0', 'T-reg': '72.1', 'GdT-cell': '89.5', 'MAIT T-cell': '61.2', 'Memory CD4 T-cell': '76.8', 'Naive CD4 T-cell': '47.0', 'Memory CD8 T-cell': '81.1', 'Naive CD8 T-cell': '43.5', 'Memory B-cell': '50.4', 'Naive B-cell': '38.5', 'Plasmacytoid DC': '47.5', 'Myeloid DC': '92.2', 'NK-cell': '88.9', 'Total PBMC': '83.8', 'Vd2 gdTCR': '67.8', 'Memory CD4 T-cell Th1\\/Th17': '48.0', 'Memory CD4 T-cell Th17': '54.6', 'Memory CD4 T-cell Th2': '54.8', 'Non-Vd2 gdTCR': '73.7', 'Memory CD4 T-cell Th1': '58.8', 'Memory CD4 T-cell TFH': '61.9', 'Terminal effector memory CD4 T-cell': '72.8', 'Central memory CD8 T-cell': '59.9', 'Effector memory CD8 T-cell': '90.7', 'Terminal effector memory CD8 T-cell': '75.8', 'Non-switched memory B-cell': '52.6', 'Plasmablast': '62.3', 'Switched memory B-cell': '55.8', 'Exhausted memory B-cell': '52.1', 'Progenitor cell': '44.7', 'Memory T-reg': '82.4', 'Naive CD4 T-cell activated': '133.9', 'Naive CD8 T-cell activated': '163.4', 'Naive T-reg': '54.7'}
2IWG, 5JPX, 5OLM, 6FGA, 6S53, 7BBD, 8A58
{'Adipose Tissue': 21.42795099667774, 'Adrenal Gland': 16.707763565891472, 'Bladder': 21.861904761904764, 'Blood': 61.11958557588805, 'Blood Vessel': 22.62928389513109, 'Brain': 4.305000416351249, 'Breast': 20.001740740740743, 'Cervix Uteri': 26.420526315789473, 'Colon': 23.40817458279846, 'Esophagus': 21.74157577854671, 'Fallopian Tube': 25.39, 'Heart': 6.66628106852497, 'Kidney': 13.61479775280899, 'Liver': 10.388, 'Lung': 32.00464878892734, 'Muscle': 3.944284806973848, 'Nerve': 25.39305008077545, 'Ovary': 30.51811111111111, 'Pancreas': 6.808080182926829, 'Pituitary': 12.995699646643107, 'Prostate': 21.00597551020408, 'Salivary Gland': 16.434148148148147, 'Skin': 17.851811498065228, 'Small Intestine': 28.907085561497325, 'Spleen': 50.16024896265561, 'Stomach': 19.072721448467966, 'Testis': 6.377013850415512, 'Thyroid': 21.553307810107196, 'Uterus': 29.83549295774648, 'Vagina': 21.551141025641027}
IFI16
MGKKYKNIVLLKGLEVINDYHFRMVKSLLSNDLKLNLKMREEYDKIQIADLMEEKFRGDAGLGKLIKIFEDIPTLEDLAETLKKEKLKVKGPALSRKRKKEVDATSPAPSTSSTVKTEGAEATPGAQKRKKSTKEKAGPKGSKVSEEQTQPPSPAGAGMSTAMGRSPSPKTSLSAPPNSSSTENPKTVAKCQVTPRRNVLQKRPVIVKVLSTTKPFEYETPEMEKKIMFHATVATQTQFFHVKVLNTSLKEKFNGKKIIIISDYLEYDSLLEVNEESTVSEAGPNQTFEVPNKIINRAKETLKIDILHKQASGNIVYGVFMLHKKTVNQKTTIYEIQDDRGKMDVVGTGQCHNIPCEEGDKLQLFCFRLRKKNQMSKLISEMHSFIQIKKKTNPRNNDPKSMKLPQEQRQLPYPSEASTTFPESHLRTPQMPPTTPSSSFFTKKSEDTISKMNDFMRMQILKEGSHFPGPFMTSIGPAESHPHTPQMPPSTPSSSFLTTKSEDTISKMNDFMRMQILKEGSHFPGPFMTSIGPAESHPHTPQMPPSTPSSSFLTTLKPRLKTEPEEVSIEDSAQSDLKEVMVLNATESFVYEPKEQKKMFHATVATENEVFRVKVFNIDLKEKFTPKKIIAIANYVCRNGFLEVYPFTLVADVNADRNMEIPKGLIRSASVTPKINQLCSQTKGSFVNGVFEVHKKNVRGEFTYYEIQDNTGKMEVVVHGRLTTINCEEGDKLKLTCFELAPKSGNTGELRSVIHSHIKVIKTRKNKKDILNPDSSMETSPDFFF
Homo sapiens
Nucleus, Cytoplasm, Cytoplasm
Low tissue specificity
{'Ciliated cells': '62.3', 'Basal respiratory cells': '190.0', 'Club cells': '105.3', 'Ionocytes': '97.9', 'Mucus glandular cells': '109.7', 'Serous glandular cells': '43.7', 'Gastric mucus-secreting cells': '6.5', 'Proximal enterocytes': '8.0', 'Paneth cells': '17.2', 'Distal enterocytes': '5.5', 'Intestinal goblet cells': '19.5', 'Exocrine glandular cells': '-0.567', 'Basal prostatic cells': '38.6', 'Prostatic glandular cells': '4.9', 'Breast glandular cells': '0.150', 'Breast myoepithelial cells': '0.244', 'Glandular and luminal cells': '69.6', 'Secretory cells': '180.9', 'Basal keratinocytes': '118.1', 'Suprabasal keratinocytes': '51.4', 'Basal squamous epithelial cells': '150.7', 'Squamous epithelial cells': '74.0', 'Alveolar cells type 1': '-0.040', 'Alveolar cells type 2': '-0.465', 'Salivary duct cells': '178.3', 'Ductal cells': '0.688', 'Hepatocytes': '0.174', 'Cholangiocytes': '43.9', 'Proximal tubular cells': '0.010', 'Distal tubular cells': '0.0', 'Collecting duct cells': '48.6', 'Mesothelial cells': '0.131', 'Sertoli cells': '0.501', 'Granulosa cells': '205.1', 'Enteroendocrine cells': '18.9', 'Pancreatic endocrine cells': '57.7', 'Leydig cells': '0.644', 'Excitatory neurons': '1.2', 'Inhibitory neurons': '2.1', 'Cone photoreceptor cells': '6.8', 'Rod photoreceptor cells': '0.4', 'Bipolar cells': '0.5', 'Horizontal cells': '0.0', 'Astrocytes': '4.0', 'Oligodendrocyte precursor cells': '34.9', 'Oligodendrocytes': '19.3', 'Microglial cells': '110.9', 'Muller glia cells': '36.1', 'Schwann cells': '0.137', 'Spermatogonia': '0.442', 'Spermatocytes': '0.022', 'Early spermatids': '-0.589', 'Late spermatids': '-0.668', 'Oocytes': '12.5', 'Cytotrophoblasts': '2.8', 'Syncytiotrophoblasts': '2.5', 'Extravillous trophoblasts': '2.3', 'Endothelial cells': '293.8', 'Lymphatic endothelial cells': '179.8', 'Cardiomyocytes': '0.103', 'Skeletal myocytes': '-0.068', 'Smooth muscle cells': '140.2', 'Adipocytes': '366.4', 'Melanocytes': '0.168', 'Fibroblasts': '180.1', 'Peritubular cells': '0.458', 'Endometrial stromal cells': '222.3', 'Ovarian stromal cells': '153.0', 'Undifferentiated cells': '27.8', 'T-cells': '206.9', 'B-cells': '237.2', 'Plasma cells': '115.9', 'Nk-cells': '393.4', 'Granulocytes': '155.9', 'Monocytes': '142.7', 'Macrophages': '196.4', 'Hofbauer cells': '227.2', 'Kupffer cells': '144.9', 'Dendritic cells': '139.1', 'Langerhans cells': '0.273', 'Erythroid cells': '0.060', 'Adipocytes (Subcutaneous)': '-0.530', 'Adipocytes (Visceral)': '-0.409', 'Breast glandular cells (progenitors)': '-0.027', 'Adipocytes (Breast)': '-0.374', 'Colon enterocytes': '-0.122', 'Colon enteroendocrine cells': '0.231', 'Enteric glia cells': '0.278', 'Mitotic cells (Colon)': '0.159', 'Mitotic cells (Heart)': '0.379', 'Podocytes': '-0.048', 'Ascending Loop of Henle cells': '0.201', 'Intercalated cells': '-0.174', 'Cholangiocyte': '0.546', 'NK-cells (Liver)': '-0.092', 'Respiratory ciliated cells': '-0.061', 'Mitotic cells (Lung)': '-0.044', 'NK-cells (Lung)': '0.444', 'B-cells (Lung)': '0.264', 'Alpha cells': '0.339', 'Beta cells': '0.156', 'Prostate glandular cells': '-0.523', 'Prostate basal glandular cells': '0.118', 'Urothelial cells': '0.421', 'Keratinocyte (other)': '0.123', 'Keratinocyte (granular)': '-0.187', 'Hair cortex cells': '-0.057', 'Inner root sheath cells': '-0.003', 'Outer root sheath cells': '0.105', 'Sebaceous gland cells': '-0.041', 'Eccrine sweat gland cells': '0.035', 'Adipocytes (Skin)': '0.024', 'Mitotic cells (Skin)': '0.243', 'Parietal cells': '-0.751', 'Chief cells': '-0.642', 'Gastric mucous cells': '-0.477', 'Gastric enteroendocrine cells': '-0.420', 'Mitotic cells (Stomach)': '-0.035', 'Parafollicular cells': '-0.087', 'Thyroid glandular cells': '-0.148', 'Mitotic cells (Thyroid)': '0.311', 'Adrenal cortex cells': '0.371', 'Adrenal medulla cells': '0.065', 'Mitotic cells (Adrenal gland)': '0.334', 'Minor salivary glandular cells': '0.655', 'Minor salivary gland ductal cells': '0.003', 'Minor salivary gland basal cells': '0.344', 'Mitotic cells (Minor salivary gland)': '0.478', 'Adipocytes (Minor salivary gland)': '0.251', 'Somatotropes': '-0.259', 'Lactotropes': '-0.440', 'Gonadotropes': '-0.140', 'Corticotropes': '-0.276', 'Thyrotropes': '-0.166', 'Undifferentiated cells (Pituitary gland)': '0.394', 'Mitotic cells (Spleen)': '-0.163', 'Platelets': '-0.180', 'Erythrocytes': '-0.152', 'Hematopoietic stem cells': '-0.246', 'B-cells (Spleen)': '0.423', 'NK-cells (Spleen)': '0.283', 'Amygdala excitatory': '5.5', 'Cerebellar inhibitory': '3.0', 'Cge interneuron': '9.5', 'Deep-layer corticothalamic and 6b': '2.5', 'Deep-layer intratelencephalic': '7.2', 'Deep-layer near-projecting': '6.6', 'Eccentric medium spiny neuron': '2.4', 'Hippocampal ca1-3': '10.6', 'Hippocampal ca4': '18.5', 'Hippocampal dentate gyrus': '15.1', 'Lamp5-lhx6 and chandelier': '1.3', 'Lower rhombic lip': '0.6', 'Mammillary body': '0.3', 'Medium spiny neuron': '0.7', 'Mge interneuron': '2.7', 'Midbrain-derived inhibitory': '3.3', 'Miscellaneous': '4.9', 'Splatter': '2.3', 'Thalamic excitatory': '0.5', 'Upper rhombic lip': '0.4', 'Upper-layer intratelencephalic': '3.1', 'Astrocyte': '37.2', 'Bergmann glia': '108.6', 'Central nervous system macrophage': '504.5', 'Choroid plexus epithelial cell': '5.6', 'Committed oligodendrocyte precursor': '16.0', 'Ependymal cell': '3.6', 'Oligodendrocyte': '31.0', 'Oligodendrocyte precursor cell': '61.4', 'Endothelial cell': '198.1', 'Pericyte': '74.7', 'Vascular associated smooth muscle cell': '71.2', 'Fibroblast': '84.9', 'Leukocyte': '347.8', 'Basophil': '35.3', 'Eosinophil': '0.4', 'Neutrophil': '1177.0', 'Classical monocyte': '101.9', 'Non-classical monocyte': '124.4', 'Intermediate monocyte': '301.7', 'T-reg': '228.2', 'GdT-cell': '57.5', 'MAIT T-cell': '172.9', 'Memory CD4 T-cell': '54.4', 'Naive CD4 T-cell': '100.4', 'Memory CD8 T-cell': '59.2', 'Naive CD8 T-cell': '67.6', 'Memory B-cell': '88.7', 'Naive B-cell': '210.3', 'Plasmacytoid DC': '349.7', 'Myeloid DC': '346.0', 'NK-cell': '265.6', 'Total PBMC': '247.0', 'Vd2 gdTCR': '206.8', 'Memory CD4 T-cell TFH': '145.4', 'Memory CD4 T-cell Th2': '145.8', 'Memory CD4 T-cell Th17': '138.0', 'Memory CD4 T-cell Th1\\/Th17': '152.0', 'Non-Vd2 gdTCR': '232.8', 'Memory CD4 T-cell Th1': '153.8', 'Terminal effector memory CD4 T-cell': '245.0', 'Central memory CD8 T-cell': '172.0', 'Effector memory CD8 T-cell': '286.1', 'Terminal effector memory CD8 T-cell': '241.4', 'Switched memory B-cell': '288.2', 'Plasmablast': '304.0', 'Non-switched memory B-cell': '275.4', 'Exhausted memory B-cell': '255.0', 'Progenitor cell': '172.3', 'Naive CD4 T-cell activated': '228.9', 'Naive CD8 T-cell activated': '189.7', 'Memory T-reg': '162.3', 'Naive T-reg': '162.9'}
2OQ0, 3B6Y, 3RLN, 3RLO, 3RNU, 4QGU, 8X70
{'Adipose Tissue': 125.56371262458472, 'Adrenal Gland': 45.70423255813953, 'Bladder': 63.83904761904761, 'Blood': 127.25510226049516, 'Blood Vessel': 71.97602996254682, 'Brain': 9.985799394398184, 'Breast': 99.8920697167756, 'Cervix Uteri': 91.98, 'Colon': 46.42050577663672, 'Esophagus': 58.1218615916955, 'Fallopian Tube': 92.16777777777776, 'Heart': 21.288962833914052, 'Kidney': 22.282831460674156, 'Liver': 7.231013274336283, 'Lung': 118.58932525951558, 'Muscle': 10.702199252801991, 'Nerve': 117.35180936995154, 'Ovary': 88.26233333333333, 'Pancreas': 6.3239021341463415, 'Pituitary': 18.176120141342754, 'Prostate': 49.08720408163265, 'Salivary Gland': 78.37074074074074, 'Skin': 88.25807075732449, 'Small Intestine': 75.11406951871658, 'Spleen': 115.98381742738589, 'Stomach': 27.265122562674097, 'Testis': 19.966318559556782, 'Thyroid': 64.80419448698316, 'Uterus': 113.35985915492958, 'Vagina': 87.93589743589743}
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[0.56, 0.19, 0.73, 0.66, 0.02, 0.21, 0.56, 0.08, 0.0, 0.23, 0.68, 0.39, 0.0, 0.0, 0.55, 0.58, 0.03, 0.57, 0.51, 0.68, 0.15, 0.07, 0.53, 0.31, 0.0, 0.07, 0.38, 0.48, 0.0, 0.1, 0.87, 0.34, 0.03, 0.77, 0.06, 0.51, 0.66, 0.62, 0.29, 0.31, 0.69, 0.65, 0.28, 0.46, 0.17, 0.54, 0.39, 0.01, 0.01, 0.42, 0.18, 0.0, 0.25, 0.64, 0.55, 0.25, 0.81, 0.66, 0.22, 0.01, 0.01, 0.0, 0.35, 0.34, 0.0, 0.07, 0.59, 0.07, 0.0, 0.46, 0.65, 0.06, 0.79, 0.72, 0.04, 0.62, 0.78, 0.19, 0.01, 0.44, 0.43, 0.0, 0.3, 0.62, 0.15, 0.18, 0.65, 0.69, 0.24, 0.68, 0.61, 1.0, 0.9, 1.0, 0.95, 1.0, 0.95, 1.0, 1.0, 0.93, 1.0, 0.88, 1.0, 1.0, 0.99, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 0.99, 1.0, 0.98, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 0.9, 1.0, 0.84, 0.99, 0.89, 1.0, 0.95, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 0.99, 0.96, 0.99, 0.97, 0.97, 1.0, 0.97, 1.0, 1.0, 1.0, 1.0, 0.98, 1.0, 0.99, 1.0, 0.99, 0.98, 0.99, 0.98, 0.99, 0.98, 1.0, 0.94, 1.0, 0.94, 1.0, 0.97, 0.99, 0.95, 0.91, 0.9, 0.87, 0.92, 0.87, 0.9, 0.91, 0.57, 0.9, 0.67, 0.48, 0.54, 0.3, 0.68, 0.84, 0.58, 0.16, 0.37, 0.0, 0.22, 0.02, 0.28, 0.52, 0.4, 0.04, 0.86, 0.5, 0.08, 0.39, 0.08, 0.57, 0.13, 0.75, 0.8, 0.7, 0.47, 0.68, 0.35, 0.51, 0.0, 0.0, 0.02, 0.02, 0.09, 0.0, 0.0, 0.15, 0.58, 0.8, 0.5, 0.24, 0.06, 0.17, 0.0, 0.14, 0.0, 0.15, 0.22, 0.36, 0.76, 0.09, 0.24, 0.73, 0.35, 0.01, 0.53, 0.51, 0.87, 0.3, 0.11, 0.0, 0.21, 0.0, 0.19, 0.32, 0.07, 0.29, 0.29, 0.23, 0.79, 0.52, 0.09, 0.0, 0.23, 0.0, 0.23, 0.71, 0.76, 0.08, 0.45, 0.09, 0.45, 0.54, 0.22, 0.42, 0.8, 0.97, 0.43, 0.71, 0.16, 0.84, 0.11, 0.48, 0.64, 0.84, 0.11, 0.24, 0.58, 0.58, 0.19, 0.72, 0.73, 0.26, 0.42, 0.33, 0.0, 0.24, 0.44, 0.0, 0.38, 0.72, 0.25, 0.6, 0.42, 0.13, 0.27, 0.24, 0.01, 0.13, 0.1, 0.35, 0.02, 0.38, 0.02, 0.23, 0.33, 0.27, 0.4, 0.41, 0.45, 0.93, 0.82, 0.31, 0.0, 0.28, 0.0, 0.22, 0.0, 0.28, 0.25, 0.81, 0.64, 0.29, 0.4, 0.02, 0.18, 0.0, 0.19, 0.0, 0.37, 0.67, 0.49, 0.01, 0.31, 0.34, 0.13, 0.77, 0.11, 0.65, 0.52, 0.52, 0.11, 0.56, 0.0, 0.2, 0.01, 0.09, 0.02, 0.0, 0.24, 0.0, 0.57, 0.41, 0.85, 0.93, 0.97, 0.54, 0.09, 0.26, 0.0, 0.39, 0.13, 0.34, 0.49, 0.09, 0.03, 0.22, 0.06, 0.39, 0.28, 0.46, 0.52, 0.81, 0.88, 0.75, 0.85, 0.9, 0.8, 0.86, 0.66, 0.92, 0.93, 0.96, 1.0, 1.0, 0.8, 1.0, 0.81, 1.0, 1.0, 1.0, 1.0, 0.99, 0.99, 0.97, 0.98, 0.95, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 0.9, 1.0, 0.91, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 0.99, 1.0, 1.0, 1.0, 0.96, 1.0, 0.73, 0.97, 0.73, 0.93, 0.93, 0.97, 0.9, 0.97, 0.98, 0.91, 0.86, 0.98, 0.94, 0.95, 0.97, 0.98, 1.0, 1.0, 1.0, 1.0, 0.96, 1.0, 0.98, 0.99, 1.0, 0.97, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 0.99, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 0.95, 1.0, 0.95, 0.88, 1.0, 0.83, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 0.97, 0.99, 0.95, 0.98, 0.83, 0.97, 0.77, 0.97, 0.99, 0.99, 0.98, 0.99, 0.93, 0.94, 0.91, 0.93, 0.96, 0.95, 0.98, 0.98, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 0.95, 1.0, 0.99, 1.0, 0.98, 1.0, 1.0, 0.99, 1.0, 0.98, 1.0, 0.98, 1.0, 0.99, 0.99, 0.91, 0.99, 0.93, 0.91, 1.0, 0.85, 1.0, 0.99, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 0.95, 0.98, 0.85, 0.94, 0.89, 0.91, 0.82, 0.85, 0.82, 0.59, 0.63, 0.5, 0.94, 0.51, 0.64, 0.44, 0.31, 0.67, 0.32, 0.69, 0.62, 0.57, 0.18, 0.27, 0.0, 0.17, 0.02, 0.21, 0.39, 0.35, 0.18, 0.49, 0.5, 0.11, 0.3, 0.15, 0.33, 0.5, 0.91, 0.65, 0.55, 0.43, 0.46, 0.0, 0.0, 0.04, 0.05, 0.05, 0.0, 0.0, 0.24, 0.46, 0.47, 0.49, 0.32, 0.14, 0.29, 0.01, 0.05, 0.0, 0.14, 0.19, 0.38, 0.83, 0.14, 0.34, 0.72, 0.32, 0.01, 0.45, 0.56, 0.8, 0.28, 0.16, 0.0, 0.1, 0.01, 0.13, 0.49, 0.02, 0.23, 0.08, 0.5, 0.56, 0.48, 0.04, 0.05, 0.03, 0.0, 0.3, 0.7, 0.65, 0.08, 0.54, 0.16, 0.38, 0.44, 0.24, 0.67, 0.89, 0.8, 0.45, 0.68, 0.1, 0.69, 0.11, 0.47, 0.77, 0.6, 0.18, 0.37, 0.75, 0.5, 0.13, 0.71, 0.61, 0.35, 0.27, 0.38, 0.0, 0.5, 0.56, 0.04, 0.19, 0.58, 0.26, 0.8, 0.53, 0.68, 0.19, 0.26, 0.05, 0.17, 0.1, 0.44, 0.02, 0.3, 0.02, 0.41, 0.51, 0.31, 0.34, 0.64, 0.74, 0.8, 0.76, 0.43, 0.03, 0.25, 0.01, 0.29, 0.0, 0.31, 0.32, 0.86, 0.38, 0.36, 0.47, 0.04, 0.37, 0.0, 0.09, 0.01, 0.47, 0.45, 0.3, 0.08, 0.3, 0.84, 0.23, 0.63, 0.0, 0.5, 0.55, 0.4, 0.06, 0.37, 0.0, 0.44, 0.02, 0.07, 0.01, 0.0, 0.38, 0.02, 0.13, 0.64, 0.44, 0.93, 0.8, 0.76, 0.55, 0.09, 0.08, 0.0, 0.45, 0.05, 0.26, 0.57, 0.18, 0.0, 0.11, 0.09, 0.45, 0.29, 0.45, 0.51, 0.53, 0.93, 0.9, 0.75, 0.83, 0.83, 0.9, 0.8, 0.79, 0.82, 0.87, 0.84, 0.95, 0.99, 1.0, 0.99, 0.99, 0.98, 1.0, 1.0, 1.0, 1.0, 1.0]
RING finger
Component of a SCF(SKP2)-like complex containing CUL1, SKP1, TRIM21 and SKP2.
SCF
null
IRF8, CALR, CUL1, FBXW11, HSPA5, IKBKB, IRF3, SKP1 , VCP,SKP2, DCP2 ,ULK1, BECN1,GABARAP, GABARAPL1, GABARAPL2 , MAP1LC3C,SQSTM1,IRF3 , NMI, IFI35 , CUL1, TRIM21
USP4, IKBKB, TRIM21, CDKN1B, IRF3, IRF8, MNI
mono, 63
null
UBE2D2, UBE2D1, UBE2E1, UBE2E2
Homotrimer
null
90.718042
0.406716
68.040217
0.580115
824
P19474
Q2F514
34097931
UbiBrowser
TRIM21
MASAARLTMMWEEVTCPICLDPFVEPVSIECGHSFCQECISQVGKGGGSVCPVCRQRFLLKNLRPNRQLANMVNNLKEISQEAREGTQGERCAVHGERLHLFCEKDGKALCWVCAQSRKHRDHAMVPLEEAAQEYQEKLQVALGELRRKQELAEKLEVEIAIKRADWKKTVETQKSRIHAEFVQQKNFLVEEEQRQLQELEKDEREQLRILGEKEAKLAQQSQALQELISELDRRCHSSALELLQEVIIVLERSESWNLKDLDITSPELRSVCHVPGLKKMLRTCAVHITLDPDTANPWLILSEDRRQVRLGDTQQSIPGNEERFDSYPMVLGAQHFHSGKHYWEVDVTGKEAWDLGVCRDSVRRKGHFLLSSKSGFWTIWLWNKQKYEAGTYPQTPLHLQVPPCQVGIFLDYEAGMVSFYNITDHGSLIYSFSECAFTGPLRPFFSPGFNDGGKNTAPLTLCPLNIGSQGSTDY
Homo sapiens
Cytoplasm, Cytoplasmic vesicle, autophagosome, Nucleus, Cytoplasm, P-body, Cytoplasm, Stress granule
Low tissue specificity
{'Ciliated cells': '3.8', 'Basal respiratory cells': '6.8', 'Club cells': '5.8', 'Ionocytes': '3.7', 'Mucus glandular cells': '4.8', 'Serous glandular cells': '2.3', 'Gastric mucus-secreting cells': '8.8', 'Proximal enterocytes': '8.9', 'Paneth cells': '3.9', 'Distal enterocytes': '8.5', 'Intestinal goblet cells': '8.4', 'Exocrine glandular cells': '-0.716', 'Basal prostatic cells': '5.4', 'Prostatic glandular cells': '5.0', 'Breast glandular cells': '0.298', 'Breast myoepithelial cells': '0.351', 'Glandular and luminal cells': '5.9', 'Secretory cells': '8.4', 'Basal keratinocytes': '3.2', 'Suprabasal keratinocytes': '2.7', 'Basal squamous epithelial cells': '6.4', 'Squamous epithelial cells': '4.3', 'Alveolar cells type 1': '0.116', 'Alveolar cells type 2': '0.115', 'Salivary duct cells': '3.0', 'Ductal cells': '0.700', 'Hepatocytes': '0.503', 'Cholangiocytes': '11.4', 'Proximal tubular cells': '0.175', 'Distal tubular cells': '0.0', 'Collecting duct cells': '5.8', 'Mesothelial cells': '0.451', 'Sertoli cells': '0.479', 'Granulosa cells': '4.8', 'Enteroendocrine cells': '3.7', 'Pancreatic endocrine cells': '3.4', 'Leydig cells': '0.632', 'Excitatory neurons': '0.2', 'Inhibitory neurons': '0.1', 'Cone photoreceptor cells': '0.0', 'Rod photoreceptor cells': '0.0', 'Bipolar cells': '0.7', 'Horizontal cells': '0.6', 'Astrocytes': '0.0', 'Oligodendrocyte precursor cells': '0.9', 'Oligodendrocytes': '0.1', 'Microglial cells': '1.8', 'Muller glia cells': '2.4', 'Schwann cells': '0.099', 'Spermatogonia': '0.401', 'Spermatocytes': '-0.062', 'Early spermatids': '-0.578', 'Late spermatids': '-0.618', 'Oocytes': '1.5', 'Cytotrophoblasts': '6.6', 'Syncytiotrophoblasts': '9.8', 'Extravillous trophoblasts': '10.0', 'Endothelial cells': '7.8', 'Lymphatic endothelial cells': '6.9', 'Cardiomyocytes': '0.335', 'Skeletal myocytes': '-0.080', 'Smooth muscle cells': '6.3', 'Adipocytes': '8.3', 'Melanocytes': '0.101', 'Fibroblasts': '6.5', 'Peritubular cells': '0.579', 'Endometrial stromal cells': '4.5', 'Ovarian stromal cells': '6.7', 'Undifferentiated cells': '5.9', 'T-cells': '9.9', 'B-cells': '8.8', 'Plasma cells': '5.0', 'Nk-cells': '15.1', 'Granulocytes': '6.2', 'Monocytes': '7.8', 'Macrophages': '8.5', 'Hofbauer cells': '9.9', 'Kupffer cells': '10.3', 'Dendritic cells': '8.0', 'Langerhans cells': '0.466', 'Erythroid cells': '-0.084', 'Adipocytes (Subcutaneous)': '-0.368', 'Adipocytes (Visceral)': '-0.167', 'Breast glandular cells (progenitors)': '0.190', 'Adipocytes (Breast)': '-0.382', 'Colon enterocytes': '0.004', 'Colon enteroendocrine cells': '0.196', 'Enteric glia cells': '-0.129', 'Mitotic cells (Colon)': '0.005', 'Mitotic cells (Heart)': '0.486', 'Podocytes': '-0.114', 'Ascending Loop of Henle cells': '0.371', 'Intercalated cells': '-0.097', 'Cholangiocyte': '0.375', 'NK-cells (Liver)': '-0.278', 'Respiratory ciliated cells': '-0.022', 'Mitotic cells (Lung)': '0.157', 'NK-cells (Lung)': '0.110', 'B-cells (Lung)': '-0.155', 'Alpha cells': '0.333', 'Beta cells': '0.161', 'Prostate glandular cells': '-0.162', 'Prostate basal glandular cells': '0.286', 'Urothelial cells': '0.283', 'Keratinocyte (other)': '0.121', 'Keratinocyte (granular)': '-0.008', 'Hair cortex cells': '-0.113', 'Inner root sheath cells': '-0.069', 'Outer root sheath cells': '0.125', 'Sebaceous gland cells': '0.110', 'Eccrine sweat gland cells': '0.070', 'Adipocytes (Skin)': '0.019', 'Mitotic cells (Skin)': '0.236', 'Parietal cells': '-0.609', 'Chief cells': '-0.599', 'Gastric mucous cells': '-0.193', 'Gastric enteroendocrine cells': '-0.441', 'Mitotic cells (Stomach)': '0.261', 'Parafollicular cells': '-0.028', 'Thyroid glandular cells': '0.094', 'Mitotic cells (Thyroid)': '0.242', 'Adrenal cortex cells': '0.619', 'Adrenal medulla cells': '0.063', 'Mitotic cells (Adrenal gland)': '0.483', 'Minor salivary glandular cells': '0.582', 'Minor salivary gland ductal cells': '0.072', 'Minor salivary gland basal cells': '0.229', 'Mitotic cells (Minor salivary gland)': '0.376', 'Adipocytes (Minor salivary gland)': '0.211', 'Somatotropes': '-0.121', 'Lactotropes': '-0.287', 'Gonadotropes': '0.004', 'Corticotropes': '-0.352', 'Thyrotropes': '-0.054', 'Undifferentiated cells (Pituitary gland)': '0.486', 'Mitotic cells (Spleen)': '-0.016', 'Platelets': '0.115', 'Erythrocytes': '0.098', 'Hematopoietic stem cells': '0.042', 'B-cells (Spleen)': '0.028', 'NK-cells (Spleen)': '0.157', 'Amygdala excitatory': '0.1', 'Cerebellar inhibitory': '0.2', 'Cge interneuron': '0.3', 'Deep-layer corticothalamic and 6b': '0.3', 'Deep-layer intratelencephalic': '0.1', 'Deep-layer near-projecting': '0.1', 'Eccentric medium spiny neuron': '0.4', 'Hippocampal ca1-3': '0.5', 'Hippocampal ca4': '0.1', 'Hippocampal dentate gyrus': '0.3', 'Lamp5-lhx6 and chandelier': '0.3', 'Lower rhombic lip': '0.2', 'Mammillary body': '0.4', 'Medium spiny neuron': '0.6', 'Mge interneuron': '0.1', 'Midbrain-derived inhibitory': '0.6', 'Miscellaneous': '0.6', 'Splatter': '0.5', 'Thalamic excitatory': '1.3', 'Upper rhombic lip': '0.1', 'Upper-layer intratelencephalic': '0.1', 'Astrocyte': '1.5', 'Bergmann glia': '1.5', 'Central nervous system macrophage': '6.0', 'Choroid plexus epithelial cell': '2.9', 'Committed oligodendrocyte precursor': '1.0', 'Ependymal cell': '1.3', 'Oligodendrocyte': '0.1', 'Oligodendrocyte precursor cell': '2.3', 'Endothelial cell': '6.4', 'Pericyte': '5.3', 'Vascular associated smooth muscle cell': '3.1', 'Fibroblast': '5.3', 'Leukocyte': '7.4', 'Basophil': '107.0', 'Eosinophil': '312.5', 'Neutrophil': '496.9', 'Classical monocyte': '25.8', 'Non-classical monocyte': '66.1', 'Intermediate monocyte': '117.0', 'T-reg': '72.1', 'GdT-cell': '89.5', 'MAIT T-cell': '61.2', 'Memory CD4 T-cell': '76.8', 'Naive CD4 T-cell': '47.0', 'Memory CD8 T-cell': '81.1', 'Naive CD8 T-cell': '43.5', 'Memory B-cell': '50.4', 'Naive B-cell': '38.5', 'Plasmacytoid DC': '47.5', 'Myeloid DC': '92.2', 'NK-cell': '88.9', 'Total PBMC': '83.8', 'Vd2 gdTCR': '67.8', 'Memory CD4 T-cell Th1\\/Th17': '48.0', 'Memory CD4 T-cell Th17': '54.6', 'Memory CD4 T-cell Th2': '54.8', 'Non-Vd2 gdTCR': '73.7', 'Memory CD4 T-cell Th1': '58.8', 'Memory CD4 T-cell TFH': '61.9', 'Terminal effector memory CD4 T-cell': '72.8', 'Central memory CD8 T-cell': '59.9', 'Effector memory CD8 T-cell': '90.7', 'Terminal effector memory CD8 T-cell': '75.8', 'Non-switched memory B-cell': '52.6', 'Plasmablast': '62.3', 'Switched memory B-cell': '55.8', 'Exhausted memory B-cell': '52.1', 'Progenitor cell': '44.7', 'Memory T-reg': '82.4', 'Naive CD4 T-cell activated': '133.9', 'Naive CD8 T-cell activated': '163.4', 'Naive T-reg': '54.7'}
2IWG, 5JPX, 5OLM, 6FGA, 6S53, 7BBD, 8A58
{'Adipose Tissue': 21.42795099667774, 'Adrenal Gland': 16.707763565891472, 'Bladder': 21.861904761904764, 'Blood': 61.11958557588805, 'Blood Vessel': 22.62928389513109, 'Brain': 4.305000416351249, 'Breast': 20.001740740740743, 'Cervix Uteri': 26.420526315789473, 'Colon': 23.40817458279846, 'Esophagus': 21.74157577854671, 'Fallopian Tube': 25.39, 'Heart': 6.66628106852497, 'Kidney': 13.61479775280899, 'Liver': 10.388, 'Lung': 32.00464878892734, 'Muscle': 3.944284806973848, 'Nerve': 25.39305008077545, 'Ovary': 30.51811111111111, 'Pancreas': 6.808080182926829, 'Pituitary': 12.995699646643107, 'Prostate': 21.00597551020408, 'Salivary Gland': 16.434148148148147, 'Skin': 17.851811498065228, 'Small Intestine': 28.907085561497325, 'Spleen': 50.16024896265561, 'Stomach': 19.072721448467966, 'Testis': 6.377013850415512, 'Thyroid': 21.553307810107196, 'Uterus': 29.83549295774648, 'Vagina': 21.551141025641027}
X
MAARLCCQLDPARDVLCLRPVGAESCGRPFSGSLGTLSSPSPSAVPTDHGAHLSLRGLPVCAFSSAGPCALRFTSARRMETTVNAHQILPKVLHKRTLGLSAMSTTDLEAYFKDCLFKDWEELGEEIRLKVFVLGGCRHKLVCAPAPCNFFTSA
Hepatitis B virus
Host cytoplasm, Host nucleus, Host mitochondrion
Not found
{}
null
{}
[37.42, 45.2, 56.71, 57.57, 65.92, 71.8, 70.72, 70.19, 75.03, 81.06, 81.95, 82.13, 85.0, 89.84, 89.65, 93.29, 90.82, 89.33, 90.46, 84.59, 85.8, 87.81, 91.19, 89.54, 92.34, 94.82, 95.66, 94.94, 93.26, 90.29, 93.55, 91.65, 95.23, 95.54, 95.57, 95.25, 94.22, 93.77, 94.59, 93.99, 92.38, 92.01, 90.02, 87.48, 84.99, 84.15, 85.0, 86.86, 92.88, 92.09, 93.98, 92.61, 92.26, 94.16, 91.11, 93.0, 91.84, 92.37, 91.85, 87.92, 88.9, 90.86, 91.4, 93.27, 94.09, 93.72, 91.24, 89.47, 90.87, 89.3, 89.1, 89.45, 87.1, 86.17, 84.68, 82.73, 79.4, 75.43, 73.11, 66.81, 58.79, 56.4, 57.14, 50.0, 41.66, 49.45, 46.98, 52.48, 63.42, 77.27, 83.26, 88.11, 83.9, 82.85, 82.24, 80.46, 83.44, 86.75, 90.36, 90.91, 92.35, 94.22, 93.97, 92.59, 91.88, 91.55, 92.54, 91.76, 92.73, 91.95, 91.78, 87.62, 88.88, 89.98, 89.02, 87.87, 87.09, 81.79, 85.41, 89.94, 86.91, 90.31, 93.19, 92.04, 92.63, 92.75, 94.0, 91.74, 90.6, 93.79, 93.32, 92.6, 94.2, 92.65, 94.04, 95.5, 94.59, 96.08, 96.87, 97.3, 97.34, 97.3, 97.9, 97.6, 97.34, 98.13, 97.9, 97.84, 98.09, 97.93, 97.74, 97.91, 97.97, 98.08, 98.06, 98.31, 98.18, 98.31, 98.27, 98.46, 98.37, 98.45, 98.48, 98.52, 98.4, 98.36, 98.42, 98.47, 98.42, 98.6, 98.52, 98.51, 98.47, 98.52, 98.65, 98.47, 98.42, 98.33, 98.15, 98.23, 97.89, 97.72, 98.12, 97.06, 94.36, 96.1, 97.22, 95.88, 95.5, 96.92, 96.41, 94.83, 95.61, 96.85, 95.68, 93.62, 94.87, 95.02, 92.66, 92.29, 93.58, 93.17, 90.83, 91.9, 93.49, 91.76, 90.61, 91.95, 92.8, 89.98, 90.53, 92.36, 91.6, 90.32, 92.11, 92.6, 91.67, 91.94, 93.15, 92.56, 91.55, 92.47, 94.89, 91.68, 93.05, 95.16, 94.98, 93.56, 95.18, 95.36, 94.15, 93.0, 95.19, 94.52, 93.31, 91.99, 94.21, 94.39, 95.42, 93.51, 92.82, 90.55, 93.43, 93.5, 91.71, 90.91, 92.74, 94.03, 93.92, 92.98, 93.7, 95.25, 93.14, 91.37, 92.48, 90.25, 87.51, 83.62, 81.45, 78.8, 68.93, 70.19, 74.93, 74.85, 73.08, 69.77, 71.48, 70.16, 74.92, 74.22, 75.09, 76.93, 84.78, 85.51, 90.71, 89.91, 89.84, 91.49, 90.63, 91.65, 93.29, 94.96, 95.3, 95.02, 96.12, 97.34, 96.84, 95.83, 97.84, 98.21, 98.67, 98.07, 97.3, 96.96, 97.78, 97.76, 97.22, 97.13, 96.39, 97.65, 97.27, 97.97, 97.63, 97.02, 96.67, 97.9, 97.82, 98.42, 98.41, 97.25, 96.71, 94.49, 92.42, 92.85, 92.74, 92.31, 91.79, 90.52, 89.07, 87.87, 94.83, 94.96, 95.48, 96.92, 96.98, 94.26, 92.55, 94.09, 95.92, 97.89, 98.55, 98.69, 98.6, 98.13, 97.79, 98.25, 98.31, 97.6, 97.52, 97.32, 98.14, 98.34, 98.46, 98.44, 98.3, 98.69, 98.53, 98.24, 96.72, 93.58, 95.96, 95.66, 96.57, 98.01, 98.18, 98.8, 98.54, 98.56, 98.0, 97.79, 96.92, 96.01, 96.29, 95.7, 95.91, 95.38, 93.83, 92.92, 93.1, 92.46, 94.65, 94.37, 91.56, 90.62, 93.46, 95.77, 97.33, 98.2, 98.4, 98.45, 98.04, 97.71, 94.75, 91.92, 91.6, 90.93, 95.37, 97.6, 97.66, 97.68, 95.74, 94.35, 89.48, 92.0, 94.21, 95.41, 95.95, 94.88, 89.49, 90.25, 84.41, 90.76, 94.36, 96.31, 97.55, 97.78, 98.41, 98.32, 98.74, 98.52, 98.58, 98.19, 98.21, 96.9, 96.87, 97.29, 98.14, 98.48, 98.28, 98.41, 97.12, 95.74, 94.98, 94.29, 91.56, 87.31, 91.26, 92.16, 94.52, 95.64, 96.72, 97.49, 97.8, 95.39, 92.34, 93.18, 90.34, 93.95, 90.82, 95.3, 97.74, 98.55, 98.51, 98.72, 98.69, 98.74, 98.17, 97.37, 94.61, 93.44, 86.86, 83.94, 83.77, 87.25, 89.38, 94.89, 94.49, 96.17, 97.62, 98.58, 98.53, 98.47, 96.86, 92.19, 89.44, 77.29, 71.65, 55.24, 43.29, 43.23, 36.26, 33.32, 36.02, 30.77, 39.9]
[0.84, 0.72, 0.66, 0.55, 0.5, 0.72, 0.31, 0.33, 0.65, 0.46, 0.08, 0.65, 0.77, 0.02, 0.29, 0.0, 0.41, 0.33, 0.38, 0.37, 0.33, 0.11, 0.07, 0.72, 0.68, 0.05, 0.02, 0.19, 0.06, 0.55, 0.26, 0.61, 0.31, 0.16, 0.0, 0.05, 0.41, 0.65, 0.18, 0.0, 0.33, 0.45, 0.36, 0.02, 0.7, 0.89, 0.4, 0.41, 0.3, 0.53, 0.01, 0.45, 0.53, 0.44, 0.79, 0.57, 0.81, 0.04, 0.45, 0.24, 0.85, 0.42, 0.21, 0.75, 0.67, 0.21, 0.75, 0.68, 0.14, 0.28, 0.45, 0.5, 0.01, 0.48, 0.49, 0.04, 0.37, 0.52, 0.49, 0.16, 0.56, 0.79, 0.81, 0.22, 0.96, 0.95, 0.7, 0.99, 0.47, 0.73, 0.4, 0.09, 0.94, 0.71, 0.06, 0.21, 0.21, 0.56, 0.17, 0.41, 0.24, 0.13, 0.0, 0.4, 0.78, 0.37, 0.57, 0.53, 0.39, 0.03, 0.0, 0.32, 0.25, 0.14, 0.09, 0.67, 0.18, 0.7, 0.71, 0.06, 0.65, 0.95, 0.2, 0.5, 0.38, 0.21, 0.51, 0.25, 0.61, 0.58, 0.04, 0.48, 0.61, 0.43, 0.36, 0.57, 0.54, 0.5, 0.61, 0.59, 0.6, 0.37, 0.51, 0.3, 0.49, 0.59, 0.64, 0.65, 0.63, 0.54, 0.51, 0.59, 0.42, 0.46, 0.64, 0.47, 0.66, 0.56, 0.42, 0.65, 0.54, 0.53, 0.57, 0.64, 0.52, 0.54, 0.69, 0.58, 0.7, 0.54, 0.34, 0.58, 0.59, 0.39, 0.55, 0.52, 0.53, 0.55, 0.65, 0.53, 0.54, 0.64, 0.37, 0.71, 0.52, 0.65, 0.49, 0.48, 0.42, 0.59, 0.64, 0.15, 0.6, 0.49, 0.55, 0.18, 0.46, 0.44, 0.46, 0.39, 0.45, 0.61, 0.18, 0.59, 0.57, 0.48, 0.26, 0.57, 0.49, 0.34, 0.33, 0.38, 0.55, 0.25, 0.7, 0.45, 0.5, 0.4, 0.52, 0.69, 0.16, 0.55, 0.54, 0.44, 0.3, 0.54, 0.57, 0.08, 0.5, 0.47, 0.23, 0.33, 0.56, 0.62, 0.15, 0.71, 0.76, 0.29, 0.52, 0.63, 0.8, 0.46, 0.41, 0.68, 0.66, 0.64, 0.29, 0.7, 0.5, 0.06, 0.47, 0.57, 0.45, 0.3, 0.79, 0.61, 0.34, 0.78, 0.55, 0.67, 0.92, 0.25, 0.65, 0.65, 0.61, 0.87, 0.49, 0.73, 0.46, 0.76, 0.2, 0.42, 0.67, 0.39, 0.53, 0.26, 0.55, 0.16, 0.3, 0.81, 0.53, 0.0, 0.37, 0.75, 0.19, 0.11, 0.24, 0.53, 0.03, 0.23, 0.02, 0.16, 0.31, 0.5, 0.01, 0.05, 0.04, 0.13, 0.43, 0.03, 0.33, 0.27, 0.25, 0.95, 0.6, 0.46, 0.24, 0.39, 0.01, 0.45, 0.13, 0.05, 0.77, 0.73, 0.6, 0.39, 0.94, 0.43, 0.81, 0.91, 0.34, 0.84, 0.52, 0.08, 0.01, 0.51, 0.51, 0.31, 0.06, 0.04, 0.0, 0.0, 0.0, 0.39, 0.25, 0.46, 0.06, 0.56, 0.58, 0.3, 0.53, 0.16, 0.0, 0.02, 0.01, 0.01, 0.34, 0.02, 0.48, 0.65, 0.09, 0.12, 0.12, 0.02, 0.18, 0.0, 0.01, 0.0, 0.0, 0.27, 0.31, 0.82, 0.08, 0.57, 0.11, 0.38, 0.23, 0.71, 0.18, 0.7, 0.16, 0.1, 0.41, 0.84, 0.35, 0.03, 0.0, 0.02, 0.0, 0.01, 0.1, 0.05, 0.75, 0.67, 0.56, 0.81, 0.57, 0.08, 0.25, 0.0, 0.01, 0.19, 0.77, 0.9, 0.55, 0.35, 0.78, 0.14, 0.82, 0.21, 0.44, 0.4, 0.65, 0.08, 0.38, 0.25, 0.0, 0.0, 0.01, 0.07, 0.0, 0.08, 0.2, 0.69, 0.56, 0.07, 0.29, 0.0, 0.02, 0.0, 0.09, 0.02, 0.05, 0.42, 0.2, 0.67, 0.05, 0.12, 0.54, 0.11, 0.22, 0.39, 0.06, 0.77, 0.91, 0.13, 0.6, 0.15, 0.58, 0.53, 0.27, 0.0, 0.03, 0.0, 0.0, 0.02, 0.02, 0.01, 0.12, 0.55, 0.14, 0.51, 0.94, 0.51, 0.59, 0.02, 0.49, 0.25, 0.36, 0.02, 0.23, 0.08, 0.23, 0.91, 0.18, 0.88, 0.53, 0.7, 0.86, 0.92, 0.76, 0.8, 0.9, 0.85, 0.99]
null
null
RING finger
Component of a SCF(SKP2)-like complex containing CUL1, SKP1, TRIM21 and SKP2.
SCF
null
IRF8, CALR, CUL1, FBXW11, HSPA5, IKBKB, IRF3, SKP1 , VCP,SKP2, DCP2 ,ULK1, BECN1,GABARAP, GABARAPL1, GABARAPL2 , MAP1LC3C,SQSTM1,IRF3 , NMI, IFI35 , CUL1, TRIM21
USP4, IKBKB, TRIM21, CDKN1B, IRF3, IRF8, MNI
mono, 63
null
UBE2D2, UBE2D1, UBE2E1, UBE2E2
Homotrimer
null
90.718042
0.406716
null
null
2,875
P19474
Q92985
21183682
UbiNet, UbiBrowser
TRIM21
MASAARLTMMWEEVTCPICLDPFVEPVSIECGHSFCQECISQVGKGGGSVCPVCRQRFLLKNLRPNRQLANMVNNLKEISQEAREGTQGERCAVHGERLHLFCEKDGKALCWVCAQSRKHRDHAMVPLEEAAQEYQEKLQVALGELRRKQELAEKLEVEIAIKRADWKKTVETQKSRIHAEFVQQKNFLVEEEQRQLQELEKDEREQLRILGEKEAKLAQQSQALQELISELDRRCHSSALELLQEVIIVLERSESWNLKDLDITSPELRSVCHVPGLKKMLRTCAVHITLDPDTANPWLILSEDRRQVRLGDTQQSIPGNEERFDSYPMVLGAQHFHSGKHYWEVDVTGKEAWDLGVCRDSVRRKGHFLLSSKSGFWTIWLWNKQKYEAGTYPQTPLHLQVPPCQVGIFLDYEAGMVSFYNITDHGSLIYSFSECAFTGPLRPFFSPGFNDGGKNTAPLTLCPLNIGSQGSTDY
Homo sapiens
Cytoplasm, Cytoplasmic vesicle, autophagosome, Nucleus, Cytoplasm, P-body, Cytoplasm, Stress granule
Low tissue specificity
{'Ciliated cells': '3.8', 'Basal respiratory cells': '6.8', 'Club cells': '5.8', 'Ionocytes': '3.7', 'Mucus glandular cells': '4.8', 'Serous glandular cells': '2.3', 'Gastric mucus-secreting cells': '8.8', 'Proximal enterocytes': '8.9', 'Paneth cells': '3.9', 'Distal enterocytes': '8.5', 'Intestinal goblet cells': '8.4', 'Exocrine glandular cells': '-0.716', 'Basal prostatic cells': '5.4', 'Prostatic glandular cells': '5.0', 'Breast glandular cells': '0.298', 'Breast myoepithelial cells': '0.351', 'Glandular and luminal cells': '5.9', 'Secretory cells': '8.4', 'Basal keratinocytes': '3.2', 'Suprabasal keratinocytes': '2.7', 'Basal squamous epithelial cells': '6.4', 'Squamous epithelial cells': '4.3', 'Alveolar cells type 1': '0.116', 'Alveolar cells type 2': '0.115', 'Salivary duct cells': '3.0', 'Ductal cells': '0.700', 'Hepatocytes': '0.503', 'Cholangiocytes': '11.4', 'Proximal tubular cells': '0.175', 'Distal tubular cells': '0.0', 'Collecting duct cells': '5.8', 'Mesothelial cells': '0.451', 'Sertoli cells': '0.479', 'Granulosa cells': '4.8', 'Enteroendocrine cells': '3.7', 'Pancreatic endocrine cells': '3.4', 'Leydig cells': '0.632', 'Excitatory neurons': '0.2', 'Inhibitory neurons': '0.1', 'Cone photoreceptor cells': '0.0', 'Rod photoreceptor cells': '0.0', 'Bipolar cells': '0.7', 'Horizontal cells': '0.6', 'Astrocytes': '0.0', 'Oligodendrocyte precursor cells': '0.9', 'Oligodendrocytes': '0.1', 'Microglial cells': '1.8', 'Muller glia cells': '2.4', 'Schwann cells': '0.099', 'Spermatogonia': '0.401', 'Spermatocytes': '-0.062', 'Early spermatids': '-0.578', 'Late spermatids': '-0.618', 'Oocytes': '1.5', 'Cytotrophoblasts': '6.6', 'Syncytiotrophoblasts': '9.8', 'Extravillous trophoblasts': '10.0', 'Endothelial cells': '7.8', 'Lymphatic endothelial cells': '6.9', 'Cardiomyocytes': '0.335', 'Skeletal myocytes': '-0.080', 'Smooth muscle cells': '6.3', 'Adipocytes': '8.3', 'Melanocytes': '0.101', 'Fibroblasts': '6.5', 'Peritubular cells': '0.579', 'Endometrial stromal cells': '4.5', 'Ovarian stromal cells': '6.7', 'Undifferentiated cells': '5.9', 'T-cells': '9.9', 'B-cells': '8.8', 'Plasma cells': '5.0', 'Nk-cells': '15.1', 'Granulocytes': '6.2', 'Monocytes': '7.8', 'Macrophages': '8.5', 'Hofbauer cells': '9.9', 'Kupffer cells': '10.3', 'Dendritic cells': '8.0', 'Langerhans cells': '0.466', 'Erythroid cells': '-0.084', 'Adipocytes (Subcutaneous)': '-0.368', 'Adipocytes (Visceral)': '-0.167', 'Breast glandular cells (progenitors)': '0.190', 'Adipocytes (Breast)': '-0.382', 'Colon enterocytes': '0.004', 'Colon enteroendocrine cells': '0.196', 'Enteric glia cells': '-0.129', 'Mitotic cells (Colon)': '0.005', 'Mitotic cells (Heart)': '0.486', 'Podocytes': '-0.114', 'Ascending Loop of Henle cells': '0.371', 'Intercalated cells': '-0.097', 'Cholangiocyte': '0.375', 'NK-cells (Liver)': '-0.278', 'Respiratory ciliated cells': '-0.022', 'Mitotic cells (Lung)': '0.157', 'NK-cells (Lung)': '0.110', 'B-cells (Lung)': '-0.155', 'Alpha cells': '0.333', 'Beta cells': '0.161', 'Prostate glandular cells': '-0.162', 'Prostate basal glandular cells': '0.286', 'Urothelial cells': '0.283', 'Keratinocyte (other)': '0.121', 'Keratinocyte (granular)': '-0.008', 'Hair cortex cells': '-0.113', 'Inner root sheath cells': '-0.069', 'Outer root sheath cells': '0.125', 'Sebaceous gland cells': '0.110', 'Eccrine sweat gland cells': '0.070', 'Adipocytes (Skin)': '0.019', 'Mitotic cells (Skin)': '0.236', 'Parietal cells': '-0.609', 'Chief cells': '-0.599', 'Gastric mucous cells': '-0.193', 'Gastric enteroendocrine cells': '-0.441', 'Mitotic cells (Stomach)': '0.261', 'Parafollicular cells': '-0.028', 'Thyroid glandular cells': '0.094', 'Mitotic cells (Thyroid)': '0.242', 'Adrenal cortex cells': '0.619', 'Adrenal medulla cells': '0.063', 'Mitotic cells (Adrenal gland)': '0.483', 'Minor salivary glandular cells': '0.582', 'Minor salivary gland ductal cells': '0.072', 'Minor salivary gland basal cells': '0.229', 'Mitotic cells (Minor salivary gland)': '0.376', 'Adipocytes (Minor salivary gland)': '0.211', 'Somatotropes': '-0.121', 'Lactotropes': '-0.287', 'Gonadotropes': '0.004', 'Corticotropes': '-0.352', 'Thyrotropes': '-0.054', 'Undifferentiated cells (Pituitary gland)': '0.486', 'Mitotic cells (Spleen)': '-0.016', 'Platelets': '0.115', 'Erythrocytes': '0.098', 'Hematopoietic stem cells': '0.042', 'B-cells (Spleen)': '0.028', 'NK-cells (Spleen)': '0.157', 'Amygdala excitatory': '0.1', 'Cerebellar inhibitory': '0.2', 'Cge interneuron': '0.3', 'Deep-layer corticothalamic and 6b': '0.3', 'Deep-layer intratelencephalic': '0.1', 'Deep-layer near-projecting': '0.1', 'Eccentric medium spiny neuron': '0.4', 'Hippocampal ca1-3': '0.5', 'Hippocampal ca4': '0.1', 'Hippocampal dentate gyrus': '0.3', 'Lamp5-lhx6 and chandelier': '0.3', 'Lower rhombic lip': '0.2', 'Mammillary body': '0.4', 'Medium spiny neuron': '0.6', 'Mge interneuron': '0.1', 'Midbrain-derived inhibitory': '0.6', 'Miscellaneous': '0.6', 'Splatter': '0.5', 'Thalamic excitatory': '1.3', 'Upper rhombic lip': '0.1', 'Upper-layer intratelencephalic': '0.1', 'Astrocyte': '1.5', 'Bergmann glia': '1.5', 'Central nervous system macrophage': '6.0', 'Choroid plexus epithelial cell': '2.9', 'Committed oligodendrocyte precursor': '1.0', 'Ependymal cell': '1.3', 'Oligodendrocyte': '0.1', 'Oligodendrocyte precursor cell': '2.3', 'Endothelial cell': '6.4', 'Pericyte': '5.3', 'Vascular associated smooth muscle cell': '3.1', 'Fibroblast': '5.3', 'Leukocyte': '7.4', 'Basophil': '107.0', 'Eosinophil': '312.5', 'Neutrophil': '496.9', 'Classical monocyte': '25.8', 'Non-classical monocyte': '66.1', 'Intermediate monocyte': '117.0', 'T-reg': '72.1', 'GdT-cell': '89.5', 'MAIT T-cell': '61.2', 'Memory CD4 T-cell': '76.8', 'Naive CD4 T-cell': '47.0', 'Memory CD8 T-cell': '81.1', 'Naive CD8 T-cell': '43.5', 'Memory B-cell': '50.4', 'Naive B-cell': '38.5', 'Plasmacytoid DC': '47.5', 'Myeloid DC': '92.2', 'NK-cell': '88.9', 'Total PBMC': '83.8', 'Vd2 gdTCR': '67.8', 'Memory CD4 T-cell Th1\\/Th17': '48.0', 'Memory CD4 T-cell Th17': '54.6', 'Memory CD4 T-cell Th2': '54.8', 'Non-Vd2 gdTCR': '73.7', 'Memory CD4 T-cell Th1': '58.8', 'Memory CD4 T-cell TFH': '61.9', 'Terminal effector memory CD4 T-cell': '72.8', 'Central memory CD8 T-cell': '59.9', 'Effector memory CD8 T-cell': '90.7', 'Terminal effector memory CD8 T-cell': '75.8', 'Non-switched memory B-cell': '52.6', 'Plasmablast': '62.3', 'Switched memory B-cell': '55.8', 'Exhausted memory B-cell': '52.1', 'Progenitor cell': '44.7', 'Memory T-reg': '82.4', 'Naive CD4 T-cell activated': '133.9', 'Naive CD8 T-cell activated': '163.4', 'Naive T-reg': '54.7'}
2IWG, 5JPX, 5OLM, 6FGA, 6S53, 7BBD, 8A58
{'Adipose Tissue': 21.42795099667774, 'Adrenal Gland': 16.707763565891472, 'Bladder': 21.861904761904764, 'Blood': 61.11958557588805, 'Blood Vessel': 22.62928389513109, 'Brain': 4.305000416351249, 'Breast': 20.001740740740743, 'Cervix Uteri': 26.420526315789473, 'Colon': 23.40817458279846, 'Esophagus': 21.74157577854671, 'Fallopian Tube': 25.39, 'Heart': 6.66628106852497, 'Kidney': 13.61479775280899, 'Liver': 10.388, 'Lung': 32.00464878892734, 'Muscle': 3.944284806973848, 'Nerve': 25.39305008077545, 'Ovary': 30.51811111111111, 'Pancreas': 6.808080182926829, 'Pituitary': 12.995699646643107, 'Prostate': 21.00597551020408, 'Salivary Gland': 16.434148148148147, 'Skin': 17.851811498065228, 'Small Intestine': 28.907085561497325, 'Spleen': 50.16024896265561, 'Stomach': 19.072721448467966, 'Testis': 6.377013850415512, 'Thyroid': 21.553307810107196, 'Uterus': 29.83549295774648, 'Vagina': 21.551141025641027}
IRF7
MALAPERAAPRVLFGEWLLGEISSGCYEGLQWLDEARTCFRVPWKHFARKDLSEADARIFKAWAVARGRWPPSSRGGGPPPEAETAERAGWKTNFRCALRSTRRFVMLRDNSGDPADPHKVYALSRELCWREGPGTDQTEAEAPAAVPPPQGGPPGPFLAHTHAGLQAPGPLPAPAGDKGDLLLQAVQQSCLADHLLTASWGADPVPTKAPGEGQEGLPLTGACAGGPGLPAGELYGWAVETTPSPGPQPAALTTGEAAAPESPHQAEPYLSPSPSACTAVQEPSPGALDVTIMYKGRTVLQKVVGHPSCTFLYGPPDPAVRATDPQQVAFPSPAELPDQKQLRYTEELLRHVAPGLHLELRGPQLWARRMGKCKVYWEVGGPPGSASPSTPACLLPRNCDTPIFDFRVFFQELVEFRARQRRGSPRYTIYLGFGQDLSAGRPKEKSLVLVKLEPWLCRVHLEGTQREGVSSLDSSSLSLCLSSANSLYDDIECFLMELEQPA
Homo sapiens
Nucleus, Cytoplasm
Tissue enhanced (liver, lymphoid tissue)
{'Ciliated cells': '21.5', 'Basal respiratory cells': '19.5', 'Club cells': '21.0', 'Ionocytes': '22.1', 'Mucus glandular cells': '12.1', 'Serous glandular cells': '9.7', 'Gastric mucus-secreting cells': '40.1', 'Proximal enterocytes': '34.2', 'Paneth cells': '32.9', 'Distal enterocytes': '46.7', 'Intestinal goblet cells': '40.4', 'Exocrine glandular cells': '-0.643', 'Basal prostatic cells': '13.7', 'Prostatic glandular cells': '7.9', 'Breast glandular cells': '0.425', 'Breast myoepithelial cells': '0.420', 'Glandular and luminal cells': '20.7', 'Secretory cells': '10.2', 'Basal keratinocytes': '21.7', 'Suprabasal keratinocytes': '19.1', 'Basal squamous epithelial cells': '15.1', 'Squamous epithelial cells': '6.1', 'Alveolar cells type 1': '0.068', 'Alveolar cells type 2': '-0.492', 'Salivary duct cells': '13.3', 'Ductal cells': '0.625', 'Hepatocytes': '0.084', 'Cholangiocytes': '11.4', 'Proximal tubular cells': '0.130', 'Distal tubular cells': '9.2', 'Collecting duct cells': '21.4', 'Mesothelial cells': '0.398', 'Sertoli cells': '0.331', 'Granulosa cells': '10.1', 'Enteroendocrine cells': '20.0', 'Pancreatic endocrine cells': '30.6', 'Leydig cells': '0.431', 'Excitatory neurons': '0.0', 'Inhibitory neurons': '0.0', 'Cone photoreceptor cells': '1.7', 'Rod photoreceptor cells': '2.8', 'Bipolar cells': '0.7', 'Horizontal cells': '0.0', 'Astrocytes': '2.8', 'Oligodendrocyte precursor cells': '0.9', 'Oligodendrocytes': '1.2', 'Microglial cells': '3.6', 'Muller glia cells': '3.2', 'Schwann cells': '0.217', 'Spermatogonia': '0.210', 'Spermatocytes': '-0.275', 'Early spermatids': '-0.561', 'Late spermatids': '-0.436', 'Oocytes': '14.0', 'Cytotrophoblasts': '5.8', 'Syncytiotrophoblasts': '22.2', 'Extravillous trophoblasts': '45.4', 'Endothelial cells': '27.9', 'Lymphatic endothelial cells': '47.7', 'Cardiomyocytes': '-0.193', 'Skeletal myocytes': '-0.160', 'Smooth muscle cells': '14.7', 'Adipocytes': '57.0', 'Melanocytes': '0.066', 'Fibroblasts': '12.8', 'Peritubular cells': '0.382', 'Endometrial stromal cells': '6.1', 'Ovarian stromal cells': '10.7', 'Undifferentiated cells': '12.1', 'T-cells': '35.3', 'B-cells': '63.6', 'Plasma cells': '57.6', 'Nk-cells': '35.6', 'Granulocytes': '11.9', 'Monocytes': '136.2', 'Macrophages': '58.5', 'Hofbauer cells': '61.8', 'Kupffer cells': '21.0', 'Dendritic cells': '1058.5', 'Langerhans cells': '0.183', 'Erythroid cells': '0.086', 'Adipocytes (Subcutaneous)': '-0.467', 'Adipocytes (Visceral)': '-0.410', 'Breast glandular cells (progenitors)': '0.227', 'Adipocytes (Breast)': '-0.639', 'Colon enterocytes': '0.006', 'Colon enteroendocrine cells': '0.122', 'Enteric glia cells': '0.435', 'Mitotic cells (Colon)': '0.171', 'Mitotic cells (Heart)': '0.104', 'Podocytes': '-0.041', 'Ascending Loop of Henle cells': '0.154', 'Intercalated cells': '-0.161', 'Cholangiocyte': '0.221', 'NK-cells (Liver)': '-0.068', 'Respiratory ciliated cells': '0.072', 'Mitotic cells (Lung)': '-0.166', 'NK-cells (Lung)': '0.480', 'B-cells (Lung)': '0.226', 'Alpha cells': '0.290', 'Beta cells': '0.164', 'Prostate glandular cells': '0.210', 'Prostate basal glandular cells': '0.426', 'Urothelial cells': '0.467', 'Keratinocyte (other)': '0.295', 'Keratinocyte (granular)': '-0.066', 'Hair cortex cells': '-0.113', 'Inner root sheath cells': '-0.093', 'Outer root sheath cells': '0.103', 'Sebaceous gland cells': '-0.243', 'Eccrine sweat gland cells': '-0.108', 'Adipocytes (Skin)': '-0.337', 'Mitotic cells (Skin)': '0.140', 'Parietal cells': '-0.263', 'Chief cells': '-0.144', 'Gastric mucous cells': '0.142', 'Gastric enteroendocrine cells': '0.065', 'Mitotic cells (Stomach)': '0.150', 'Parafollicular cells': '0.004', 'Thyroid glandular cells': '-0.071', 'Mitotic cells (Thyroid)': '0.026', 'Adrenal cortex cells': '0.041', 'Adrenal medulla cells': '0.094', 'Mitotic cells (Adrenal gland)': '-0.144', 'Minor salivary glandular cells': '0.499', 'Minor salivary gland ductal cells': '0.055', 'Minor salivary gland basal cells': '0.108', 'Mitotic cells (Minor salivary gland)': '0.197', 'Adipocytes (Minor salivary gland)': '0.147', 'Somatotropes': '-0.298', 'Lactotropes': '-0.306', 'Gonadotropes': '-0.144', 'Corticotropes': '0.083', 'Thyrotropes': '-0.012', 'Undifferentiated cells (Pituitary gland)': '0.199', 'Mitotic cells (Spleen)': '-0.001', 'Platelets': '-0.107', 'Erythrocytes': '0.102', 'Hematopoietic stem cells': '-0.199', 'B-cells (Spleen)': '0.125', 'NK-cells (Spleen)': '0.195', 'Amygdala excitatory': '0.1', 'Cerebellar inhibitory': '0.3', 'Cge interneuron': '0.3', 'Deep-layer corticothalamic and 6b': '0.1', 'Deep-layer intratelencephalic': '0.1', 'Deep-layer near-projecting': '0.1', 'Eccentric medium spiny neuron': '0.1', 'Hippocampal ca1-3': '0.1', 'Hippocampal ca4': '0.8', 'Hippocampal dentate gyrus': '0.2', 'Lamp5-lhx6 and chandelier': '0.2', 'Lower rhombic lip': '0.0', 'Mammillary body': '0.1', 'Medium spiny neuron': '0.0', 'Mge interneuron': '0.1', 'Midbrain-derived inhibitory': '0.0', 'Miscellaneous': '0.0', 'Splatter': '0.4', 'Thalamic excitatory': '0.1', 'Upper rhombic lip': '2.2', 'Upper-layer intratelencephalic': '0.0', 'Astrocyte': '7.3', 'Bergmann glia': '5.0', 'Central nervous system macrophage': '19.1', 'Choroid plexus epithelial cell': '11.7', 'Committed oligodendrocyte precursor': '2.2', 'Ependymal cell': '6.0', 'Oligodendrocyte': '1.8', 'Oligodendrocyte precursor cell': '2.3', 'Endothelial cell': '34.4', 'Pericyte': '8.2', 'Vascular associated smooth muscle cell': '6.8', 'Fibroblast': '7.3', 'Leukocyte': '19.4', 'Basophil': '46.1', 'Eosinophil': '30.7', 'Neutrophil': '129.5', 'Classical monocyte': '50.9', 'Non-classical monocyte': '36.9', 'Intermediate monocyte': '87.7', 'T-reg': '23.7', 'GdT-cell': '8.1', 'MAIT T-cell': '26.5', 'Memory CD4 T-cell': '6.7', 'Naive CD4 T-cell': '11.8', 'Memory CD8 T-cell': '7.0', 'Naive CD8 T-cell': '18.1', 'Memory B-cell': '16.6', 'Naive B-cell': '13.0', 'Plasmacytoid DC': '1371.7', 'Myeloid DC': '87.9', 'NK-cell': '23.4', 'Total PBMC': '21.3', 'Vd2 gdTCR': '22.4', 'Memory CD4 T-cell TFH': '47.4', 'Memory CD4 T-cell Th2': '23.5', 'Memory CD4 T-cell Th17': '21.6', 'Memory CD4 T-cell Th1\\/Th17': '11.3', 'Non-Vd2 gdTCR': '15.6', 'Memory CD4 T-cell Th1': '25.9', 'Terminal effector memory CD4 T-cell': '1.3', 'Central memory CD8 T-cell': '19.2', 'Effector memory CD8 T-cell': '18.2', 'Terminal effector memory CD8 T-cell': '14.0', 'Switched memory B-cell': '59.3', 'Plasmablast': '124.8', 'Non-switched memory B-cell': '42.2', 'Exhausted memory B-cell': '76.1', 'Progenitor cell': '21.1', 'Naive CD4 T-cell activated': '14.9', 'Naive CD8 T-cell activated': '18.6', 'Memory T-reg': '41.0', 'Naive T-reg': '22.2'}
2O61
{'Adipose Tissue': 27.812443521594684, 'Adrenal Gland': 7.714255813953488, 'Bladder': 18.238095238095237, 'Blood': 116.96281270182992, 'Blood Vessel': 17.866871910112362, 'Brain': 9.179954769114309, 'Breast': 28.970784313725492, 'Cervix Uteri': 33.107894736842105, 'Colon': 20.529478818998715, 'Esophagus': 22.21950588235294, 'Fallopian Tube': 25.66311111111111, 'Heart': 10.348394889663185, 'Kidney': 29.212089887640452, 'Liver': 43.80686725663717, 'Lung': 54.38915224913495, 'Muscle': 12.547231631382315, 'Nerve': 28.578126009693054, 'Ovary': 22.735144444444444, 'Pancreas': 8.019759146341464, 'Pituitary': 29.988964664310956, 'Prostate': 39.40589795918367, 'Salivary Gland': 24.936314814814818, 'Skin': 20.5120685461581, 'Small Intestine': 40.334994652406415, 'Spleen': 92.7714937759336, 'Stomach': 20.750089136490253, 'Testis': 10.164026869806094, 'Thyroid': 51.98919142419602, 'Uterus': 24.41595774647887, 'Vagina': 26.497211538461535}
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RING finger
Component of a SCF(SKP2)-like complex containing CUL1, SKP1, TRIM21 and SKP2.
SCF
null
IRF8, CALR, CUL1, FBXW11, HSPA5, IKBKB, IRF3, SKP1 , VCP,SKP2, DCP2 ,ULK1, BECN1,GABARAP, GABARAPL1, GABARAPL2 , MAP1LC3C,SQSTM1,IRF3 , NMI, IFI35 , CUL1, TRIM21
USP4, IKBKB, TRIM21, CDKN1B, IRF3, IRF8, MNI
mono, 63
null
UBE2D2, UBE2D1, UBE2E1, UBE2E2
Homotrimer
null
90.718042
0.406716
68.180537
0.537396
1,575
P19474
Q9C035
18312418, E3Net
UbiNet, UbiBrowser, 31181401
TRIM21
MASAARLTMMWEEVTCPICLDPFVEPVSIECGHSFCQECISQVGKGGGSVCPVCRQRFLLKNLRPNRQLANMVNNLKEISQEAREGTQGERCAVHGERLHLFCEKDGKALCWVCAQSRKHRDHAMVPLEEAAQEYQEKLQVALGELRRKQELAEKLEVEIAIKRADWKKTVETQKSRIHAEFVQQKNFLVEEEQRQLQELEKDEREQLRILGEKEAKLAQQSQALQELISELDRRCHSSALELLQEVIIVLERSESWNLKDLDITSPELRSVCHVPGLKKMLRTCAVHITLDPDTANPWLILSEDRRQVRLGDTQQSIPGNEERFDSYPMVLGAQHFHSGKHYWEVDVTGKEAWDLGVCRDSVRRKGHFLLSSKSGFWTIWLWNKQKYEAGTYPQTPLHLQVPPCQVGIFLDYEAGMVSFYNITDHGSLIYSFSECAFTGPLRPFFSPGFNDGGKNTAPLTLCPLNIGSQGSTDY
Homo sapiens
Cytoplasm, Cytoplasmic vesicle, autophagosome, Nucleus, Cytoplasm, P-body, Cytoplasm, Stress granule
Low tissue specificity
{'Ciliated cells': '3.8', 'Basal respiratory cells': '6.8', 'Club cells': '5.8', 'Ionocytes': '3.7', 'Mucus glandular cells': '4.8', 'Serous glandular cells': '2.3', 'Gastric mucus-secreting cells': '8.8', 'Proximal enterocytes': '8.9', 'Paneth cells': '3.9', 'Distal enterocytes': '8.5', 'Intestinal goblet cells': '8.4', 'Exocrine glandular cells': '-0.716', 'Basal prostatic cells': '5.4', 'Prostatic glandular cells': '5.0', 'Breast glandular cells': '0.298', 'Breast myoepithelial cells': '0.351', 'Glandular and luminal cells': '5.9', 'Secretory cells': '8.4', 'Basal keratinocytes': '3.2', 'Suprabasal keratinocytes': '2.7', 'Basal squamous epithelial cells': '6.4', 'Squamous epithelial cells': '4.3', 'Alveolar cells type 1': '0.116', 'Alveolar cells type 2': '0.115', 'Salivary duct cells': '3.0', 'Ductal cells': '0.700', 'Hepatocytes': '0.503', 'Cholangiocytes': '11.4', 'Proximal tubular cells': '0.175', 'Distal tubular cells': '0.0', 'Collecting duct cells': '5.8', 'Mesothelial cells': '0.451', 'Sertoli cells': '0.479', 'Granulosa cells': '4.8', 'Enteroendocrine cells': '3.7', 'Pancreatic endocrine cells': '3.4', 'Leydig cells': '0.632', 'Excitatory neurons': '0.2', 'Inhibitory neurons': '0.1', 'Cone photoreceptor cells': '0.0', 'Rod photoreceptor cells': '0.0', 'Bipolar cells': '0.7', 'Horizontal cells': '0.6', 'Astrocytes': '0.0', 'Oligodendrocyte precursor cells': '0.9', 'Oligodendrocytes': '0.1', 'Microglial cells': '1.8', 'Muller glia cells': '2.4', 'Schwann cells': '0.099', 'Spermatogonia': '0.401', 'Spermatocytes': '-0.062', 'Early spermatids': '-0.578', 'Late spermatids': '-0.618', 'Oocytes': '1.5', 'Cytotrophoblasts': '6.6', 'Syncytiotrophoblasts': '9.8', 'Extravillous trophoblasts': '10.0', 'Endothelial cells': '7.8', 'Lymphatic endothelial cells': '6.9', 'Cardiomyocytes': '0.335', 'Skeletal myocytes': '-0.080', 'Smooth muscle cells': '6.3', 'Adipocytes': '8.3', 'Melanocytes': '0.101', 'Fibroblasts': '6.5', 'Peritubular cells': '0.579', 'Endometrial stromal cells': '4.5', 'Ovarian stromal cells': '6.7', 'Undifferentiated cells': '5.9', 'T-cells': '9.9', 'B-cells': '8.8', 'Plasma cells': '5.0', 'Nk-cells': '15.1', 'Granulocytes': '6.2', 'Monocytes': '7.8', 'Macrophages': '8.5', 'Hofbauer cells': '9.9', 'Kupffer cells': '10.3', 'Dendritic cells': '8.0', 'Langerhans cells': '0.466', 'Erythroid cells': '-0.084', 'Adipocytes (Subcutaneous)': '-0.368', 'Adipocytes (Visceral)': '-0.167', 'Breast glandular cells (progenitors)': '0.190', 'Adipocytes (Breast)': '-0.382', 'Colon enterocytes': '0.004', 'Colon enteroendocrine cells': '0.196', 'Enteric glia cells': '-0.129', 'Mitotic cells (Colon)': '0.005', 'Mitotic cells (Heart)': '0.486', 'Podocytes': '-0.114', 'Ascending Loop of Henle cells': '0.371', 'Intercalated cells': '-0.097', 'Cholangiocyte': '0.375', 'NK-cells (Liver)': '-0.278', 'Respiratory ciliated cells': '-0.022', 'Mitotic cells (Lung)': '0.157', 'NK-cells (Lung)': '0.110', 'B-cells (Lung)': '-0.155', 'Alpha cells': '0.333', 'Beta cells': '0.161', 'Prostate glandular cells': '-0.162', 'Prostate basal glandular cells': '0.286', 'Urothelial cells': '0.283', 'Keratinocyte (other)': '0.121', 'Keratinocyte (granular)': '-0.008', 'Hair cortex cells': '-0.113', 'Inner root sheath cells': '-0.069', 'Outer root sheath cells': '0.125', 'Sebaceous gland cells': '0.110', 'Eccrine sweat gland cells': '0.070', 'Adipocytes (Skin)': '0.019', 'Mitotic cells (Skin)': '0.236', 'Parietal cells': '-0.609', 'Chief cells': '-0.599', 'Gastric mucous cells': '-0.193', 'Gastric enteroendocrine cells': '-0.441', 'Mitotic cells (Stomach)': '0.261', 'Parafollicular cells': '-0.028', 'Thyroid glandular cells': '0.094', 'Mitotic cells (Thyroid)': '0.242', 'Adrenal cortex cells': '0.619', 'Adrenal medulla cells': '0.063', 'Mitotic cells (Adrenal gland)': '0.483', 'Minor salivary glandular cells': '0.582', 'Minor salivary gland ductal cells': '0.072', 'Minor salivary gland basal cells': '0.229', 'Mitotic cells (Minor salivary gland)': '0.376', 'Adipocytes (Minor salivary gland)': '0.211', 'Somatotropes': '-0.121', 'Lactotropes': '-0.287', 'Gonadotropes': '0.004', 'Corticotropes': '-0.352', 'Thyrotropes': '-0.054', 'Undifferentiated cells (Pituitary gland)': '0.486', 'Mitotic cells (Spleen)': '-0.016', 'Platelets': '0.115', 'Erythrocytes': '0.098', 'Hematopoietic stem cells': '0.042', 'B-cells (Spleen)': '0.028', 'NK-cells (Spleen)': '0.157', 'Amygdala excitatory': '0.1', 'Cerebellar inhibitory': '0.2', 'Cge interneuron': '0.3', 'Deep-layer corticothalamic and 6b': '0.3', 'Deep-layer intratelencephalic': '0.1', 'Deep-layer near-projecting': '0.1', 'Eccentric medium spiny neuron': '0.4', 'Hippocampal ca1-3': '0.5', 'Hippocampal ca4': '0.1', 'Hippocampal dentate gyrus': '0.3', 'Lamp5-lhx6 and chandelier': '0.3', 'Lower rhombic lip': '0.2', 'Mammillary body': '0.4', 'Medium spiny neuron': '0.6', 'Mge interneuron': '0.1', 'Midbrain-derived inhibitory': '0.6', 'Miscellaneous': '0.6', 'Splatter': '0.5', 'Thalamic excitatory': '1.3', 'Upper rhombic lip': '0.1', 'Upper-layer intratelencephalic': '0.1', 'Astrocyte': '1.5', 'Bergmann glia': '1.5', 'Central nervous system macrophage': '6.0', 'Choroid plexus epithelial cell': '2.9', 'Committed oligodendrocyte precursor': '1.0', 'Ependymal cell': '1.3', 'Oligodendrocyte': '0.1', 'Oligodendrocyte precursor cell': '2.3', 'Endothelial cell': '6.4', 'Pericyte': '5.3', 'Vascular associated smooth muscle cell': '3.1', 'Fibroblast': '5.3', 'Leukocyte': '7.4', 'Basophil': '107.0', 'Eosinophil': '312.5', 'Neutrophil': '496.9', 'Classical monocyte': '25.8', 'Non-classical monocyte': '66.1', 'Intermediate monocyte': '117.0', 'T-reg': '72.1', 'GdT-cell': '89.5', 'MAIT T-cell': '61.2', 'Memory CD4 T-cell': '76.8', 'Naive CD4 T-cell': '47.0', 'Memory CD8 T-cell': '81.1', 'Naive CD8 T-cell': '43.5', 'Memory B-cell': '50.4', 'Naive B-cell': '38.5', 'Plasmacytoid DC': '47.5', 'Myeloid DC': '92.2', 'NK-cell': '88.9', 'Total PBMC': '83.8', 'Vd2 gdTCR': '67.8', 'Memory CD4 T-cell Th1\\/Th17': '48.0', 'Memory CD4 T-cell Th17': '54.6', 'Memory CD4 T-cell Th2': '54.8', 'Non-Vd2 gdTCR': '73.7', 'Memory CD4 T-cell Th1': '58.8', 'Memory CD4 T-cell TFH': '61.9', 'Terminal effector memory CD4 T-cell': '72.8', 'Central memory CD8 T-cell': '59.9', 'Effector memory CD8 T-cell': '90.7', 'Terminal effector memory CD8 T-cell': '75.8', 'Non-switched memory B-cell': '52.6', 'Plasmablast': '62.3', 'Switched memory B-cell': '55.8', 'Exhausted memory B-cell': '52.1', 'Progenitor cell': '44.7', 'Memory T-reg': '82.4', 'Naive CD4 T-cell activated': '133.9', 'Naive CD8 T-cell activated': '163.4', 'Naive T-reg': '54.7'}
2IWG, 5JPX, 5OLM, 6FGA, 6S53, 7BBD, 8A58
{'Adipose Tissue': 21.42795099667774, 'Adrenal Gland': 16.707763565891472, 'Bladder': 21.861904761904764, 'Blood': 61.11958557588805, 'Blood Vessel': 22.62928389513109, 'Brain': 4.305000416351249, 'Breast': 20.001740740740743, 'Cervix Uteri': 26.420526315789473, 'Colon': 23.40817458279846, 'Esophagus': 21.74157577854671, 'Fallopian Tube': 25.39, 'Heart': 6.66628106852497, 'Kidney': 13.61479775280899, 'Liver': 10.388, 'Lung': 32.00464878892734, 'Muscle': 3.944284806973848, 'Nerve': 25.39305008077545, 'Ovary': 30.51811111111111, 'Pancreas': 6.808080182926829, 'Pituitary': 12.995699646643107, 'Prostate': 21.00597551020408, 'Salivary Gland': 16.434148148148147, 'Skin': 17.851811498065228, 'Small Intestine': 28.907085561497325, 'Spleen': 50.16024896265561, 'Stomach': 19.072721448467966, 'Testis': 6.377013850415512, 'Thyroid': 21.553307810107196, 'Uterus': 29.83549295774648, 'Vagina': 21.551141025641027}
TRIM5
MASGILVNVKEEVTCPICLELLTQPLSLDCGHSFCQACLTANHKKSMLDKGESSCPVCRISYQPENIRPNRHVANIVEKLREVKLSPEGQKVDHCARHGEKLLLFCQEDGKVICWLCERSQEHRGHHTFLTEEVAREYQVKLQAALEMLRQKQQEAEELEADIREEKASWKTQIQYDKTNVLADFEQLRDILDWEESNELQNLEKEEEDILKSLTNSETEMVQQTQSLRELISDLEHRLQGSVMELLQGVDGVIKRTENVTLKKPETFPKNQRRVFRAPDLKGMLEVFRELTDVRRYWVDVTVAPNNISCAVISEDKRQVSSPKPQIIYGARGTRYQTFVNFNYCTGILGSQSITSGKHYWEVDVSKKTAWILGVCAGFQPDAMCNIEKNENYQPKYGYWVIGLEEGVKCSAFQDSSFHTPSVPFIVPLSVIICPDRVGVFLDYEACTVSFFNITNHGFLIYKFSHCSFSQPVFPYLNPRKCGVPMTLCSPSS
Homo sapiens
Cytoplasm, Nucleus
Low tissue specificity
{'Ciliated cells': '6.4', 'Basal respiratory cells': '8.3', 'Club cells': '14.2', 'Ionocytes': '7.0', 'Mucus glandular cells': '9.8', 'Serous glandular cells': '14.2', 'Gastric mucus-secreting cells': '7.7', 'Proximal enterocytes': '6.4', 'Paneth cells': '5.5', 'Distal enterocytes': '5.2', 'Intestinal goblet cells': '11.5', 'Exocrine glandular cells': '-0.438', 'Basal prostatic cells': '17.1', 'Prostatic glandular cells': '13.8', 'Breast glandular cells': '0.491', 'Breast myoepithelial cells': '0.595', 'Glandular and luminal cells': '13.2', 'Secretory cells': '14.1', 'Basal keratinocytes': '7.3', 'Suprabasal keratinocytes': '10.3', 'Basal squamous epithelial cells': '9.3', 'Squamous epithelial cells': '6.9', 'Alveolar cells type 1': '0.133', 'Alveolar cells type 2': '-0.113', 'Salivary duct cells': '8.6', 'Ductal cells': '0.490', 'Hepatocytes': '0.447', 'Cholangiocytes': '1.9', 'Proximal tubular cells': '0.175', 'Distal tubular cells': '3.1', 'Collecting duct cells': '9.7', 'Mesothelial cells': '0.470', 'Sertoli cells': '0.457', 'Granulosa cells': '8.8', 'Enteroendocrine cells': '4.6', 'Pancreatic endocrine cells': '1.7', 'Leydig cells': '0.594', 'Excitatory neurons': '2.9', 'Inhibitory neurons': '1.4', 'Cone photoreceptor cells': '0.0', 'Rod photoreceptor cells': '0.0', 'Bipolar cells': '1.1', 'Horizontal cells': '0.6', 'Astrocytes': '4.6', 'Oligodendrocyte precursor cells': '2.8', 'Oligodendrocytes': '1.0', 'Microglial cells': '18.8', 'Muller glia cells': '7.4', 'Schwann cells': '0.043', 'Spermatogonia': '0.455', 'Spermatocytes': '0.041', 'Early spermatids': '-0.459', 'Late spermatids': '-0.645', 'Oocytes': '8.1', 'Cytotrophoblasts': '7.7', 'Syncytiotrophoblasts': '7.4', 'Extravillous trophoblasts': '11.1', 'Endothelial cells': '16.2', 'Lymphatic endothelial cells': '17.8', 'Cardiomyocytes': '0.387', 'Skeletal myocytes': '-0.014', 'Smooth muscle cells': '12.0', 'Adipocytes': '13.0', 'Melanocytes': '0.095', 'Fibroblasts': '12.4', 'Peritubular cells': '0.587', 'Endometrial stromal cells': '12.3', 'Ovarian stromal cells': '12.2', 'Undifferentiated cells': '6.5', 'T-cells': '9.3', 'B-cells': '9.4', 'Plasma cells': '7.4', 'Nk-cells': '12.3', 'Granulocytes': '6.0', 'Monocytes': '10.8', 'Macrophages': '12.1', 'Hofbauer cells': '6.7', 'Kupffer cells': '19.0', 'Dendritic cells': '22.9', 'Langerhans cells': '0.264', 'Erythroid cells': '-0.110', 'Adipocytes (Subcutaneous)': '-0.439', 'Adipocytes (Visceral)': '-0.420', 'Breast glandular cells (progenitors)': '0.327', 'Adipocytes (Breast)': '-0.548', 'Colon enterocytes': '-0.079', 'Colon enteroendocrine cells': '0.297', 'Enteric glia cells': '0.432', 'Mitotic cells (Colon)': '0.050', 'Mitotic cells (Heart)': '0.574', 'Podocytes': '-0.131', 'Ascending Loop of Henle cells': '0.466', 'Intercalated cells': '-0.099', 'Cholangiocyte': '0.261', 'NK-cells (Liver)': '-0.246', 'Respiratory ciliated cells': '-0.081', 'Mitotic cells (Lung)': '0.138', 'NK-cells (Lung)': '0.316', 'B-cells (Lung)': '0.079', 'Alpha cells': '0.331', 'Beta cells': '0.208', 'Prostate glandular cells': '0.215', 'Prostate basal glandular cells': '0.350', 'Urothelial cells': '0.233', 'Keratinocyte (other)': '0.228', 'Keratinocyte (granular)': '-0.204', 'Hair cortex cells': '-0.042', 'Inner root sheath cells': '-0.002', 'Outer root sheath cells': '0.278', 'Sebaceous gland cells': '0.086', 'Eccrine sweat gland cells': '0.149', 'Adipocytes (Skin)': '-0.068', 'Mitotic cells (Skin)': '0.453', 'Parietal cells': '-0.415', 'Chief cells': '-0.210', 'Gastric mucous cells': '-0.145', 'Gastric enteroendocrine cells': '-0.137', 'Mitotic cells (Stomach)': '0.228', 'Parafollicular cells': '0.037', 'Thyroid glandular cells': '0.277', 'Mitotic cells (Thyroid)': '0.064', 'Adrenal cortex cells': '0.476', 'Adrenal medulla cells': '-0.056', 'Mitotic cells (Adrenal gland)': '0.364', 'Minor salivary glandular cells': '0.160', 'Minor salivary gland ductal cells': '0.304', 'Minor salivary gland basal cells': '0.178', 'Mitotic cells (Minor salivary gland)': '0.229', 'Adipocytes (Minor salivary gland)': '0.048', 'Somatotropes': '-0.144', 'Lactotropes': '-0.410', 'Gonadotropes': '0.035', 'Corticotropes': '-0.378', 'Thyrotropes': '-0.210', 'Undifferentiated cells (Pituitary gland)': '0.475', 'Mitotic cells (Spleen)': '-0.122', 'Platelets': '-0.076', 'Erythrocytes': '-0.068', 'Hematopoietic stem cells': '-0.180', 'B-cells (Spleen)': '0.213', 'NK-cells (Spleen)': '0.354', 'Amygdala excitatory': '11.9', 'Cerebellar inhibitory': '4.8', 'Cge interneuron': '4.0', 'Deep-layer corticothalamic and 6b': '32.8', 'Deep-layer intratelencephalic': '16.5', 'Deep-layer near-projecting': '56.0', 'Eccentric medium spiny neuron': '8.6', 'Hippocampal ca1-3': '30.6', 'Hippocampal ca4': '7.2', 'Hippocampal dentate gyrus': '6.0', 'Lamp5-lhx6 and chandelier': '4.0', 'Lower rhombic lip': '23.7', 'Mammillary body': '9.1', 'Medium spiny neuron': '7.2', 'Mge interneuron': '4.0', 'Midbrain-derived inhibitory': '5.3', 'Miscellaneous': '25.8', 'Splatter': '11.1', 'Thalamic excitatory': '12.0', 'Upper rhombic lip': '1.6', 'Upper-layer intratelencephalic': '6.1', 'Astrocyte': '12.0', 'Bergmann glia': '2.8', 'Central nervous system macrophage': '74.2', 'Choroid plexus epithelial cell': '42.4', 'Committed oligodendrocyte precursor': '5.6', 'Ependymal cell': '29.0', 'Oligodendrocyte': '1.1', 'Oligodendrocyte precursor cell': '1.6', 'Endothelial cell': '30.7', 'Pericyte': '18.6', 'Vascular associated smooth muscle cell': '12.6', 'Fibroblast': '31.2', 'Leukocyte': '42.1', 'Basophil': '43.5', 'Eosinophil': '9.6', 'Neutrophil': '110.7', 'Classical monocyte': '12.4', 'Non-classical monocyte': '18.5', 'Intermediate monocyte': '44.7', 'T-reg': '16.2', 'GdT-cell': '4.7', 'MAIT T-cell': '30.0', 'Memory CD4 T-cell': '3.9', 'Naive CD4 T-cell': '23.2', 'Memory CD8 T-cell': '4.1', 'Naive CD8 T-cell': '19.7', 'Memory B-cell': '3.6', 'Naive B-cell': '14.7', 'Plasmacytoid DC': '62.1', 'Myeloid DC': '41.6', 'NK-cell': '25.7', 'Total PBMC': '31.3', 'Vd2 gdTCR': '17.1', 'Memory CD4 T-cell Th1\\/Th17': '14.8', 'Memory CD4 T-cell Th17': '12.8', 'Memory CD4 T-cell Th2': '14.3', 'Non-Vd2 gdTCR': '28.1', 'Memory CD4 T-cell Th1': '15.0', 'Memory CD4 T-cell TFH': '16.1', 'Terminal effector memory CD4 T-cell': '33.9', 'Central memory CD8 T-cell': '22.7', 'Effector memory CD8 T-cell': '26.1', 'Terminal effector memory CD8 T-cell': '28.9', 'Non-switched memory B-cell': '27.5', 'Plasmablast': '38.8', 'Switched memory B-cell': '27.4', 'Exhausted memory B-cell': '29.0', 'Progenitor cell': '46.7', 'Memory T-reg': '12.8', 'Naive CD4 T-cell activated': '45.1', 'Naive CD8 T-cell activated': '39.3', 'Naive T-reg': '21.6'}
2ECV, 2YRG
{'Adipose Tissue': 10.969098837209302, 'Adrenal Gland': 13.147356589147288, 'Bladder': 12.744380952380952, 'Blood': 13.579995801937567, 'Blood Vessel': 16.373662172284643, 'Brain': 1.5696437925813775, 'Breast': 10.99218954248366, 'Cervix Uteri': 20.141052631578948, 'Colon': 9.455770218228498, 'Esophagus': 9.55905051903114, 'Fallopian Tube': 17.538888888888888, 'Heart': 3.8654873403019745, 'Kidney': 7.739887640449439, 'Liver': 9.244703539823009, 'Lung': 20.0074169550173, 'Muscle': 1.3000332503113323, 'Nerve': 13.308712439418418, 'Ovary': 19.186466666666664, 'Pancreas': 9.326978658536584, 'Pituitary': 6.854228621908127, 'Prostate': 14.908922448979592, 'Salivary Gland': 10.115771604938272, 'Skin': 10.636239911553345, 'Small Intestine': 12.090732620320855, 'Spleen': 17.419668049792534, 'Stomach': 8.49808913649025, 'Testis': 5.809271468144044, 'Thyroid': 18.790088820826952, 'Uterus': 20.816901408450704, 'Vagina': 14.35102564102564}
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[0.87, 0.62, 0.7, 0.49, 0.61, 0.44, 0.52, 0.6, 0.38, 0.47, 0.69, 0.83, 0.04, 0.24, 0.0, 0.47, 0.43, 0.42, 0.72, 0.67, 0.18, 0.04, 0.56, 0.69, 0.06, 0.14, 0.18, 0.05, 0.59, 0.29, 0.65, 0.3, 0.18, 0.0, 0.06, 0.41, 0.7, 0.14, 0.03, 0.47, 0.52, 0.27, 0.24, 0.66, 0.69, 0.15, 0.51, 0.84, 0.85, 0.87, 0.58, 0.7, 0.05, 0.37, 0.01, 0.39, 0.48, 0.38, 0.82, 0.57, 0.66, 0.07, 0.66, 0.44, 0.88, 0.42, 0.28, 0.76, 0.71, 0.23, 0.78, 0.73, 0.16, 0.29, 0.58, 0.42, 0.02, 0.54, 0.57, 0.11, 0.37, 0.47, 0.59, 0.71, 0.74, 0.75, 0.91, 1.0, 0.84, 0.82, 0.89, 0.22, 0.68, 0.6, 0.11, 0.94, 0.62, 0.41, 0.55, 0.38, 0.51, 0.21, 0.46, 0.16, 0.14, 0.0, 0.57, 0.54, 0.35, 0.58, 0.5, 0.51, 0.04, 0.0, 0.55, 0.41, 0.08, 0.35, 0.8, 0.18, 0.89, 0.59, 0.03, 0.79, 0.85, 0.32, 0.55, 0.31, 0.39, 0.52, 0.24, 0.72, 0.61, 0.11, 0.48, 0.73, 0.53, 0.44, 0.66, 0.66, 0.54, 0.66, 0.47, 0.46, 0.33, 0.43, 0.49, 0.58, 0.63, 0.54, 0.59, 0.52, 0.55, 0.58, 0.41, 0.51, 0.51, 0.63, 0.57, 0.47, 0.48, 0.53, 0.64, 0.55, 0.7, 0.55, 0.75, 0.51, 0.58, 0.58, 0.7, 0.67, 0.48, 0.48, 0.52, 0.63, 0.39, 0.5, 0.62, 0.33, 0.53, 0.65, 0.39, 0.53, 0.5, 0.55, 0.55, 0.46, 0.51, 0.58, 0.6, 0.51, 0.58, 0.69, 0.46, 0.62, 0.54, 0.3, 0.15, 0.53, 0.64, 0.39, 0.4, 0.63, 0.63, 0.18, 0.57, 0.69, 0.52, 0.25, 0.5, 0.63, 0.34, 0.43, 0.53, 0.55, 0.13, 0.65, 0.49, 0.53, 0.37, 0.59, 0.61, 0.18, 0.38, 0.43, 0.54, 0.29, 0.54, 0.58, 0.11, 0.51, 0.54, 0.24, 0.36, 0.53, 0.62, 0.22, 0.73, 0.84, 0.42, 0.47, 0.66, 0.72, 0.42, 0.43, 0.61, 0.62, 0.58, 0.3, 0.65, 0.44, 0.05, 0.46, 0.6, 0.48, 0.43, 0.71, 0.71, 0.42, 0.77, 0.64, 0.71, 0.92, 0.32, 0.79, 0.69, 0.34, 0.42, 0.83, 0.9, 0.7, 0.65, 0.6, 0.71, 0.56, 0.9, 0.81, 0.57, 0.61, 0.39, 0.69, 0.25, 0.39, 0.54, 0.38, 0.23, 0.42, 0.57, 0.52, 0.08, 0.59, 0.36, 0.09, 0.4, 0.76, 0.39, 0.21, 0.32, 0.46, 0.11, 0.29, 0.02, 0.4, 0.74, 0.28, 1.0, 0.34, 0.21, 0.3, 0.18, 0.46, 0.29, 0.28, 0.93, 0.57, 0.5, 0.17, 0.39, 0.0, 0.21, 0.07, 0.34, 0.91, 0.57, 0.64, 0.53, 0.45, 0.64, 0.29, 0.99, 0.93, 0.71, 0.39, 0.76, 0.52, 0.69, 0.39, 0.62, 0.56, 0.58, 0.25, 0.79, 0.61, 0.02, 0.02, 0.0, 0.0, 0.13, 0.1, 0.45, 0.69, 0.53, 0.07, 0.52, 0.6, 0.33, 0.42, 0.21, 0.0, 0.01, 0.0, 0.0, 0.34, 0.02, 0.36, 0.81, 0.07, 0.48, 0.23, 0.0, 0.01, 0.0, 0.01, 0.0, 0.0, 0.18, 0.13, 0.24, 0.5, 0.73, 0.88, 0.34, 0.63, 0.93, 0.48, 0.2, 0.29, 0.49, 0.25, 0.24, 0.21, 0.03, 0.0, 0.18, 0.53, 0.39, 0.08, 0.08, 0.03, 0.0, 0.0, 0.01, 0.04, 0.42, 0.66, 0.25, 0.68, 0.53, 0.04, 0.15, 0.0, 0.01, 0.37, 0.43, 0.2, 0.9, 0.75, 0.92, 0.68, 0.56, 0.51, 0.64, 0.08, 0.57, 0.45, 0.22, 0.8, 0.14, 0.92, 0.26, 0.89, 0.49, 0.42, 0.05, 0.42, 0.2, 0.0, 0.0, 0.01, 0.09, 0.0, 0.09, 0.18, 0.66, 0.53, 0.29, 0.12, 0.0, 0.06, 0.0, 0.03, 0.01, 0.17, 0.38, 0.13, 0.58, 0.0, 0.39, 0.47, 0.12, 0.2, 0.55, 0.06, 0.67, 0.86, 0.05, 0.71, 0.14, 0.89, 0.54, 0.42, 0.0, 0.23, 0.05, 0.02, 0.04, 0.03, 0.0, 0.17, 0.68, 0.09, 0.59, 0.39, 0.38, 0.0, 0.26, 0.03, 0.11, 0.34, 0.51, 0.92, 0.5]
RING finger
Component of a SCF(SKP2)-like complex containing CUL1, SKP1, TRIM21 and SKP2.
SCF
null
IRF8, CALR, CUL1, FBXW11, HSPA5, IKBKB, IRF3, SKP1 , VCP,SKP2, DCP2 ,ULK1, BECN1,GABARAP, GABARAPL1, GABARAPL2 , MAP1LC3C,SQSTM1,IRF3 , NMI, IFI35 , CUL1, TRIM21
USP4, IKBKB, TRIM21, CDKN1B, IRF3, IRF8, MNI
mono, 63
null
UBE2D2, UBE2D1, UBE2E1, UBE2E2
Homotrimer
null
90.718042
0.406716
86.277748
0.430751
1,596
P19474
Q9H211
16407252
UbiNet, UbiBrowser
TRIM21
MASAARLTMMWEEVTCPICLDPFVEPVSIECGHSFCQECISQVGKGGGSVCPVCRQRFLLKNLRPNRQLANMVNNLKEISQEAREGTQGERCAVHGERLHLFCEKDGKALCWVCAQSRKHRDHAMVPLEEAAQEYQEKLQVALGELRRKQELAEKLEVEIAIKRADWKKTVETQKSRIHAEFVQQKNFLVEEEQRQLQELEKDEREQLRILGEKEAKLAQQSQALQELISELDRRCHSSALELLQEVIIVLERSESWNLKDLDITSPELRSVCHVPGLKKMLRTCAVHITLDPDTANPWLILSEDRRQVRLGDTQQSIPGNEERFDSYPMVLGAQHFHSGKHYWEVDVTGKEAWDLGVCRDSVRRKGHFLLSSKSGFWTIWLWNKQKYEAGTYPQTPLHLQVPPCQVGIFLDYEAGMVSFYNITDHGSLIYSFSECAFTGPLRPFFSPGFNDGGKNTAPLTLCPLNIGSQGSTDY
Homo sapiens
Cytoplasm, Cytoplasmic vesicle, autophagosome, Nucleus, Cytoplasm, P-body, Cytoplasm, Stress granule
Low tissue specificity
{'Ciliated cells': '3.8', 'Basal respiratory cells': '6.8', 'Club cells': '5.8', 'Ionocytes': '3.7', 'Mucus glandular cells': '4.8', 'Serous glandular cells': '2.3', 'Gastric mucus-secreting cells': '8.8', 'Proximal enterocytes': '8.9', 'Paneth cells': '3.9', 'Distal enterocytes': '8.5', 'Intestinal goblet cells': '8.4', 'Exocrine glandular cells': '-0.716', 'Basal prostatic cells': '5.4', 'Prostatic glandular cells': '5.0', 'Breast glandular cells': '0.298', 'Breast myoepithelial cells': '0.351', 'Glandular and luminal cells': '5.9', 'Secretory cells': '8.4', 'Basal keratinocytes': '3.2', 'Suprabasal keratinocytes': '2.7', 'Basal squamous epithelial cells': '6.4', 'Squamous epithelial cells': '4.3', 'Alveolar cells type 1': '0.116', 'Alveolar cells type 2': '0.115', 'Salivary duct cells': '3.0', 'Ductal cells': '0.700', 'Hepatocytes': '0.503', 'Cholangiocytes': '11.4', 'Proximal tubular cells': '0.175', 'Distal tubular cells': '0.0', 'Collecting duct cells': '5.8', 'Mesothelial cells': '0.451', 'Sertoli cells': '0.479', 'Granulosa cells': '4.8', 'Enteroendocrine cells': '3.7', 'Pancreatic endocrine cells': '3.4', 'Leydig cells': '0.632', 'Excitatory neurons': '0.2', 'Inhibitory neurons': '0.1', 'Cone photoreceptor cells': '0.0', 'Rod photoreceptor cells': '0.0', 'Bipolar cells': '0.7', 'Horizontal cells': '0.6', 'Astrocytes': '0.0', 'Oligodendrocyte precursor cells': '0.9', 'Oligodendrocytes': '0.1', 'Microglial cells': '1.8', 'Muller glia cells': '2.4', 'Schwann cells': '0.099', 'Spermatogonia': '0.401', 'Spermatocytes': '-0.062', 'Early spermatids': '-0.578', 'Late spermatids': '-0.618', 'Oocytes': '1.5', 'Cytotrophoblasts': '6.6', 'Syncytiotrophoblasts': '9.8', 'Extravillous trophoblasts': '10.0', 'Endothelial cells': '7.8', 'Lymphatic endothelial cells': '6.9', 'Cardiomyocytes': '0.335', 'Skeletal myocytes': '-0.080', 'Smooth muscle cells': '6.3', 'Adipocytes': '8.3', 'Melanocytes': '0.101', 'Fibroblasts': '6.5', 'Peritubular cells': '0.579', 'Endometrial stromal cells': '4.5', 'Ovarian stromal cells': '6.7', 'Undifferentiated cells': '5.9', 'T-cells': '9.9', 'B-cells': '8.8', 'Plasma cells': '5.0', 'Nk-cells': '15.1', 'Granulocytes': '6.2', 'Monocytes': '7.8', 'Macrophages': '8.5', 'Hofbauer cells': '9.9', 'Kupffer cells': '10.3', 'Dendritic cells': '8.0', 'Langerhans cells': '0.466', 'Erythroid cells': '-0.084', 'Adipocytes (Subcutaneous)': '-0.368', 'Adipocytes (Visceral)': '-0.167', 'Breast glandular cells (progenitors)': '0.190', 'Adipocytes (Breast)': '-0.382', 'Colon enterocytes': '0.004', 'Colon enteroendocrine cells': '0.196', 'Enteric glia cells': '-0.129', 'Mitotic cells (Colon)': '0.005', 'Mitotic cells (Heart)': '0.486', 'Podocytes': '-0.114', 'Ascending Loop of Henle cells': '0.371', 'Intercalated cells': '-0.097', 'Cholangiocyte': '0.375', 'NK-cells (Liver)': '-0.278', 'Respiratory ciliated cells': '-0.022', 'Mitotic cells (Lung)': '0.157', 'NK-cells (Lung)': '0.110', 'B-cells (Lung)': '-0.155', 'Alpha cells': '0.333', 'Beta cells': '0.161', 'Prostate glandular cells': '-0.162', 'Prostate basal glandular cells': '0.286', 'Urothelial cells': '0.283', 'Keratinocyte (other)': '0.121', 'Keratinocyte (granular)': '-0.008', 'Hair cortex cells': '-0.113', 'Inner root sheath cells': '-0.069', 'Outer root sheath cells': '0.125', 'Sebaceous gland cells': '0.110', 'Eccrine sweat gland cells': '0.070', 'Adipocytes (Skin)': '0.019', 'Mitotic cells (Skin)': '0.236', 'Parietal cells': '-0.609', 'Chief cells': '-0.599', 'Gastric mucous cells': '-0.193', 'Gastric enteroendocrine cells': '-0.441', 'Mitotic cells (Stomach)': '0.261', 'Parafollicular cells': '-0.028', 'Thyroid glandular cells': '0.094', 'Mitotic cells (Thyroid)': '0.242', 'Adrenal cortex cells': '0.619', 'Adrenal medulla cells': '0.063', 'Mitotic cells (Adrenal gland)': '0.483', 'Minor salivary glandular cells': '0.582', 'Minor salivary gland ductal cells': '0.072', 'Minor salivary gland basal cells': '0.229', 'Mitotic cells (Minor salivary gland)': '0.376', 'Adipocytes (Minor salivary gland)': '0.211', 'Somatotropes': '-0.121', 'Lactotropes': '-0.287', 'Gonadotropes': '0.004', 'Corticotropes': '-0.352', 'Thyrotropes': '-0.054', 'Undifferentiated cells (Pituitary gland)': '0.486', 'Mitotic cells (Spleen)': '-0.016', 'Platelets': '0.115', 'Erythrocytes': '0.098', 'Hematopoietic stem cells': '0.042', 'B-cells (Spleen)': '0.028', 'NK-cells (Spleen)': '0.157', 'Amygdala excitatory': '0.1', 'Cerebellar inhibitory': '0.2', 'Cge interneuron': '0.3', 'Deep-layer corticothalamic and 6b': '0.3', 'Deep-layer intratelencephalic': '0.1', 'Deep-layer near-projecting': '0.1', 'Eccentric medium spiny neuron': '0.4', 'Hippocampal ca1-3': '0.5', 'Hippocampal ca4': '0.1', 'Hippocampal dentate gyrus': '0.3', 'Lamp5-lhx6 and chandelier': '0.3', 'Lower rhombic lip': '0.2', 'Mammillary body': '0.4', 'Medium spiny neuron': '0.6', 'Mge interneuron': '0.1', 'Midbrain-derived inhibitory': '0.6', 'Miscellaneous': '0.6', 'Splatter': '0.5', 'Thalamic excitatory': '1.3', 'Upper rhombic lip': '0.1', 'Upper-layer intratelencephalic': '0.1', 'Astrocyte': '1.5', 'Bergmann glia': '1.5', 'Central nervous system macrophage': '6.0', 'Choroid plexus epithelial cell': '2.9', 'Committed oligodendrocyte precursor': '1.0', 'Ependymal cell': '1.3', 'Oligodendrocyte': '0.1', 'Oligodendrocyte precursor cell': '2.3', 'Endothelial cell': '6.4', 'Pericyte': '5.3', 'Vascular associated smooth muscle cell': '3.1', 'Fibroblast': '5.3', 'Leukocyte': '7.4', 'Basophil': '107.0', 'Eosinophil': '312.5', 'Neutrophil': '496.9', 'Classical monocyte': '25.8', 'Non-classical monocyte': '66.1', 'Intermediate monocyte': '117.0', 'T-reg': '72.1', 'GdT-cell': '89.5', 'MAIT T-cell': '61.2', 'Memory CD4 T-cell': '76.8', 'Naive CD4 T-cell': '47.0', 'Memory CD8 T-cell': '81.1', 'Naive CD8 T-cell': '43.5', 'Memory B-cell': '50.4', 'Naive B-cell': '38.5', 'Plasmacytoid DC': '47.5', 'Myeloid DC': '92.2', 'NK-cell': '88.9', 'Total PBMC': '83.8', 'Vd2 gdTCR': '67.8', 'Memory CD4 T-cell Th1\\/Th17': '48.0', 'Memory CD4 T-cell Th17': '54.6', 'Memory CD4 T-cell Th2': '54.8', 'Non-Vd2 gdTCR': '73.7', 'Memory CD4 T-cell Th1': '58.8', 'Memory CD4 T-cell TFH': '61.9', 'Terminal effector memory CD4 T-cell': '72.8', 'Central memory CD8 T-cell': '59.9', 'Effector memory CD8 T-cell': '90.7', 'Terminal effector memory CD8 T-cell': '75.8', 'Non-switched memory B-cell': '52.6', 'Plasmablast': '62.3', 'Switched memory B-cell': '55.8', 'Exhausted memory B-cell': '52.1', 'Progenitor cell': '44.7', 'Memory T-reg': '82.4', 'Naive CD4 T-cell activated': '133.9', 'Naive CD8 T-cell activated': '163.4', 'Naive T-reg': '54.7'}
2IWG, 5JPX, 5OLM, 6FGA, 6S53, 7BBD, 8A58
{'Adipose Tissue': 21.42795099667774, 'Adrenal Gland': 16.707763565891472, 'Bladder': 21.861904761904764, 'Blood': 61.11958557588805, 'Blood Vessel': 22.62928389513109, 'Brain': 4.305000416351249, 'Breast': 20.001740740740743, 'Cervix Uteri': 26.420526315789473, 'Colon': 23.40817458279846, 'Esophagus': 21.74157577854671, 'Fallopian Tube': 25.39, 'Heart': 6.66628106852497, 'Kidney': 13.61479775280899, 'Liver': 10.388, 'Lung': 32.00464878892734, 'Muscle': 3.944284806973848, 'Nerve': 25.39305008077545, 'Ovary': 30.51811111111111, 'Pancreas': 6.808080182926829, 'Pituitary': 12.995699646643107, 'Prostate': 21.00597551020408, 'Salivary Gland': 16.434148148148147, 'Skin': 17.851811498065228, 'Small Intestine': 28.907085561497325, 'Spleen': 50.16024896265561, 'Stomach': 19.072721448467966, 'Testis': 6.377013850415512, 'Thyroid': 21.553307810107196, 'Uterus': 29.83549295774648, 'Vagina': 21.551141025641027}
CDT1
MEQRRVTDFFARRRPGPPRIAPPKLACRTPSPARPALRAPASATSGSRKRARPPAAPGRDQARPPARRRLRLSVDEVSSPSTPEAPDIPACPSPGQKIKKSTPAAGQPPHLTSAQDQDTISELASCLQRARELGARVRALKASAQDAGESCTPEAEGRPEEPCGEKAPAYQRFHALAQPGLPGLVLPYKYQVLAEMFRSMDTIVGMLHNRSETPTFAKVQRGVQDMMRRRFEECNVGQIKTVYPASYRFRQERSVPTFKDGTRRSDYQLTIEPLLEQEADGAAPQLTASRLLQRRQIFSQKLVEHVKEHHKAFLASLSPAMVVPEDQLTRWHPRFNVDEVPDIEPAALPQPPATEKLTTAQEVLARARNLISPRMEKALSQLALRSAAPSSPGSPRPALPATPPATPPAASPSALKGVSQDLLERIRAKEAQKQLAQMTRCPEQEQRLQRLERLPELARVLRSVFVSERKPALSMEVACARMVGSCCTIMSPGEMEKHLLLLSELLPDWLSLHRIRTDTYVKLDKAADLAHITARLAHQTRAEEGL
Homo sapiens
Nucleus, Chromosome, centromere, kinetochore
Tissue enriched (bone)
{'Ciliated cells': '2.8', 'Basal respiratory cells': '1.1', 'Club cells': '4.6', 'Ionocytes': '0.0', 'Mucus glandular cells': '0.8', 'Serous glandular cells': '2.4', 'Gastric mucus-secreting cells': '9.4', 'Proximal enterocytes': '1.1', 'Paneth cells': '3.3', 'Distal enterocytes': '1.5', 'Intestinal goblet cells': '11.5', 'Exocrine glandular cells': '-0.394', 'Basal prostatic cells': '0.3', 'Prostatic glandular cells': '0.3', 'Breast glandular cells': '0.428', 'Breast myoepithelial cells': '0.477', 'Glandular and luminal cells': '2.2', 'Secretory cells': '2.9', 'Basal keratinocytes': '13.4', 'Suprabasal keratinocytes': '6.5', 'Basal squamous epithelial cells': '7.3', 'Squamous epithelial cells': '10.0', 'Alveolar cells type 1': '-0.274', 'Alveolar cells type 2': '0.144', 'Salivary duct cells': '2.6', 'Ductal cells': '0.455', 'Hepatocytes': '0.170', 'Cholangiocytes': '1.9', 'Proximal tubular cells': '0.339', 'Distal tubular cells': '0.0', 'Collecting duct cells': '1.9', 'Mesothelial cells': '0.064', 'Sertoli cells': '0.174', 'Granulosa cells': '6.5', 'Enteroendocrine cells': '4.9', 'Pancreatic endocrine cells': '5.1', 'Leydig cells': '0.177', 'Excitatory neurons': '0.2', 'Inhibitory neurons': '0.8', 'Cone photoreceptor cells': '1.7', 'Rod photoreceptor cells': '2.2', 'Bipolar cells': '1.0', 'Horizontal cells': '0.0', 'Astrocytes': '0.6', 'Oligodendrocyte precursor cells': '0.0', 'Oligodendrocytes': '0.6', 'Microglial cells': '0.0', 'Muller glia cells': '0.1', 'Schwann cells': '0.069', 'Spermatogonia': '0.456', 'Spermatocytes': '0.403', 'Early spermatids': '-0.010', 'Late spermatids': '-0.195', 'Oocytes': '27.2', 'Cytotrophoblasts': '55.2', 'Syncytiotrophoblasts': '27.1', 'Extravillous trophoblasts': '94.5', 'Endothelial cells': '1.9', 'Lymphatic endothelial cells': '0.1', 'Cardiomyocytes': '0.310', 'Skeletal myocytes': '-0.106', 'Smooth muscle cells': '1.6', 'Adipocytes': '0.6', 'Melanocytes': '0.433', 'Fibroblasts': '3.2', 'Peritubular cells': '0.080', 'Endometrial stromal cells': '1.2', 'Ovarian stromal cells': '0.9', 'Undifferentiated cells': '58.8', 'T-cells': '4.4', 'B-cells': '2.1', 'Plasma cells': '24.1', 'Nk-cells': '3.4', 'Granulocytes': '0.5', 'Monocytes': '0.7', 'Macrophages': '2.5', 'Hofbauer cells': '13.4', 'Kupffer cells': '3.7', 'Dendritic cells': '1.6', 'Langerhans cells': '0.256', 'Erythroid cells': '0.073', 'Adipocytes (Subcutaneous)': '-0.161', 'Adipocytes (Visceral)': '-0.136', 'Breast glandular cells (progenitors)': '0.478', 'Adipocytes (Breast)': '-0.403', 'Colon enterocytes': '0.351', 'Colon enteroendocrine cells': '0.008', 'Enteric glia cells': '-0.108', 'Mitotic cells (Colon)': '0.643', 'Mitotic cells (Heart)': '0.718', 'Podocytes': '-0.021', 'Ascending Loop of Henle cells': '0.255', 'Intercalated cells': '0.023', 'Cholangiocyte': '0.194', 'NK-cells (Liver)': '0.016', 'Respiratory ciliated cells': '0.126', 'Mitotic cells (Lung)': '0.831', 'NK-cells (Lung)': '-0.136', 'B-cells (Lung)': '0.014', 'Alpha cells': '0.273', 'Beta cells': '0.122', 'Prostate glandular cells': '0.031', 'Prostate basal glandular cells': '0.365', 'Urothelial cells': '0.442', 'Keratinocyte (other)': '0.426', 'Keratinocyte (granular)': '-0.160', 'Hair cortex cells': '-0.079', 'Inner root sheath cells': '0.050', 'Outer root sheath cells': '0.102', 'Sebaceous gland cells': '0.138', 'Eccrine sweat gland cells': '-0.219', 'Adipocytes (Skin)': '-0.303', 'Mitotic cells (Skin)': '0.657', 'Parietal cells': '0.123', 'Chief cells': '0.150', 'Gastric mucous cells': '0.566', 'Gastric enteroendocrine cells': '0.275', 'Mitotic cells (Stomach)': '0.882', 'Parafollicular cells': '0.040', 'Thyroid glandular cells': '0.217', 'Mitotic cells (Thyroid)': '0.447', 'Adrenal cortex cells': '0.388', 'Adrenal medulla cells': '0.120', 'Mitotic cells (Adrenal gland)': '0.426', 'Minor salivary glandular cells': '0.152', 'Minor salivary gland ductal cells': '-0.307', 'Minor salivary gland basal cells': '0.713', 'Mitotic cells (Minor salivary gland)': '0.902', 'Adipocytes (Minor salivary gland)': '0.230', 'Somatotropes': '0.293', 'Lactotropes': '0.157', 'Gonadotropes': '0.509', 'Corticotropes': '-0.046', 'Thyrotropes': '0.124', 'Undifferentiated cells (Pituitary gland)': '-0.129', 'Mitotic cells (Spleen)': '0.896', 'Platelets': '0.184', 'Erythrocytes': '0.354', 'Hematopoietic stem cells': '0.426', 'B-cells (Spleen)': '-0.129', 'NK-cells (Spleen)': '-0.235', 'Amygdala excitatory': '0.1', 'Cerebellar inhibitory': '0.5', 'Cge interneuron': '0.8', 'Deep-layer corticothalamic and 6b': '0.2', 'Deep-layer intratelencephalic': '0.2', 'Deep-layer near-projecting': '0.1', 'Eccentric medium spiny neuron': '0.1', 'Hippocampal ca1-3': '0.2', 'Hippocampal ca4': '0.0', 'Hippocampal dentate gyrus': '0.0', 'Lamp5-lhx6 and chandelier': '0.9', 'Lower rhombic lip': '2.1', 'Mammillary body': '2.4', 'Medium spiny neuron': '0.1', 'Mge interneuron': '1.3', 'Midbrain-derived inhibitory': '0.3', 'Miscellaneous': '0.1', 'Splatter': '1.0', 'Thalamic excitatory': '1.9', 'Upper rhombic lip': '0.1', 'Upper-layer intratelencephalic': '0.3', 'Astrocyte': '0.4', 'Bergmann glia': '0.1', 'Central nervous system macrophage': '0.3', 'Choroid plexus epithelial cell': '0.7', 'Committed oligodendrocyte precursor': '0.7', 'Ependymal cell': '0.3', 'Oligodendrocyte': '0.7', 'Oligodendrocyte precursor cell': '0.3', 'Endothelial cell': '0.4', 'Pericyte': '0.0', 'Vascular associated smooth muscle cell': '0.0', 'Fibroblast': '0.2', 'Leukocyte': '0.3', 'Basophil': '1.0', 'Eosinophil': '0.9', 'Neutrophil': '1.1', 'Classical monocyte': '0.4', 'Non-classical monocyte': '0.3', 'Intermediate monocyte': '0.7', 'T-reg': '1.7', 'GdT-cell': '0.3', 'MAIT T-cell': '0.9', 'Memory CD4 T-cell': '0.1', 'Naive CD4 T-cell': '0.6', 'Memory CD8 T-cell': '0.2', 'Naive CD8 T-cell': '0.8', 'Memory B-cell': '0.1', 'Naive B-cell': '0.5', 'Plasmacytoid DC': '1.0', 'Myeloid DC': '1.0', 'NK-cell': '1.3', 'Total PBMC': '0.7', 'Vd2 gdTCR': '0.7', 'Memory CD4 T-cell Th1\\/Th17': '0.7', 'Memory CD4 T-cell Th17': '1.0', 'Memory CD4 T-cell Th2': '1.2', 'Non-Vd2 gdTCR': '1.0', 'Memory CD4 T-cell Th1': '1.7', 'Memory CD4 T-cell TFH': '1.3', 'Terminal effector memory CD4 T-cell': '0.8', 'Central memory CD8 T-cell': '1.5', 'Effector memory CD8 T-cell': '2.6', 'Terminal effector memory CD8 T-cell': '0.7', 'Non-switched memory B-cell': '1.4', 'Plasmablast': '5.2', 'Switched memory B-cell': '1.4', 'Exhausted memory B-cell': '1.0', 'Progenitor cell': '2.9', 'Memory T-reg': '5.2', 'Naive CD4 T-cell activated': '0.8', 'Naive CD8 T-cell activated': '0.7', 'Naive T-reg': '1.0'}
2LE8, 2WVR, 6QCG
{'Adipose Tissue': 0.997032292358804, 'Adrenal Gland': 1.227092635658915, 'Bladder': 1.301604761904762, 'Blood': 12.7793571474704, 'Blood Vessel': 0.7174999999999999, 'Brain': 1.4977787660862982, 'Breast': 1.335659259259259, 'Cervix Uteri': 2.0814999999999997, 'Colon': 2.999952349165597, 'Esophagus': 4.487542719723184, 'Fallopian Tube': 1.0524555555555557, 'Heart': 0.4318970731707317, 'Kidney': 0.9587134831460676, 'Liver': 0.8305952654867257, 'Lung': 2.966329411764706, 'Muscle': 0.1187660747198007, 'Nerve': 1.0357840064620356, 'Ovary': 1.1274627777777777, 'Pancreas': 0.4520226524390244, 'Pituitary': 4.336411307420495, 'Prostate': 1.6580167346938774, 'Salivary Gland': 1.9630783950617283, 'Skin': 9.914025870646766, 'Small Intestine': 4.978587700534759, 'Spleen': 5.5936319502074685, 'Stomach': 2.5023571866295264, 'Testis': 8.897642659279779, 'Thyroid': 1.4817228177641657, 'Uterus': 0.9327278873239436, 'Vagina': 4.677952564102564}
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[1.0, 1.0, 0.99, 0.97, 0.96, 0.94, 0.92, 0.95, 1.0, 1.0, 1.0, 0.99, 0.98, 0.98, 0.96, 0.94, 0.96, 0.95, 0.96, 0.96, 0.94, 0.95, 0.95, 0.98, 0.92, 0.93, 0.9, 0.96, 0.94, 0.96, 0.99, 1.0, 1.0, 0.99, 1.0, 0.98, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 0.98, 0.99, 0.95, 0.99, 0.92, 0.96, 0.98, 0.94, 0.91, 0.99, 0.91, 0.93, 0.84, 0.89, 0.88, 0.79, 0.92, 0.84, 0.94, 0.92, 0.91, 0.91, 0.91, 0.89, 0.94, 0.9, 0.95, 0.94, 0.85, 0.92, 0.91, 0.89, 0.85, 0.93, 0.89, 0.93, 0.95, 0.86, 0.97, 0.97, 0.94, 0.96, 0.96, 0.98, 0.98, 1.0, 1.0, 0.99, 0.97, 1.0, 0.9, 0.99, 0.93, 1.0, 0.74, 0.83, 0.58, 0.68, 0.67, 0.7, 0.61, 0.57, 0.67, 0.58, 0.68, 0.62, 0.49, 0.38, 0.51, 0.51, 0.56, 0.54, 0.56, 0.68, 0.55, 0.59, 0.36, 0.47, 0.7, 0.53, 0.71, 0.53, 0.66, 0.66, 0.44, 0.5, 0.66, 0.75, 0.73, 0.62, 0.73, 0.93, 0.78, 0.9, 1.0, 0.86, 1.0, 0.96, 0.97, 0.97, 0.91, 0.92, 0.9, 0.82, 0.84, 0.87, 0.59, 0.96, 0.66, 0.53, 0.46, 0.53, 0.66, 0.36, 0.46, 0.55, 0.12, 0.19, 0.79, 0.73, 0.41, 0.93, 0.86, 0.61, 0.61, 0.27, 0.28, 0.28, 0.18, 0.0, 0.17, 0.34, 0.03, 0.34, 0.16, 0.04, 0.23, 0.41, 0.09, 0.0, 0.61, 0.08, 0.0, 0.02, 0.37, 0.08, 0.0, 0.04, 0.55, 0.06, 0.28, 0.37, 0.63, 0.85, 0.31, 0.43, 0.07, 0.02, 0.08, 0.59, 0.29, 0.0, 0.21, 0.69, 0.19, 0.01, 0.33, 0.63, 0.5, 0.18, 0.88, 0.49, 0.76, 0.01, 0.37, 0.48, 0.5, 0.14, 0.0, 0.03, 0.21, 0.0, 0.26, 0.36, 0.04, 0.16, 0.57, 0.57, 0.01, 0.03, 0.54, 0.15, 0.43, 0.24, 0.33, 0.52, 0.7, 0.18, 0.85, 0.37, 0.95, 0.79, 0.94, 0.85, 0.66, 0.78, 0.81, 0.53, 0.57, 0.29, 0.28, 0.07, 0.04, 0.01, 0.41, 0.08, 0.41, 0.27, 0.71, 0.86, 0.51, 0.96, 0.87, 0.79, 0.58, 0.81, 0.41, 0.56, 0.03, 0.41, 0.63, 0.65, 0.23, 0.26, 0.46, 0.43, 0.05, 0.46, 0.57, 0.28, 0.01, 0.38, 0.58, 0.35, 0.0, 0.18, 0.41, 0.27, 0.0, 0.18, 0.62, 0.35, 0.02, 0.58, 0.58, 0.24, 0.03, 0.57, 0.73, 0.17, 0.78, 0.44, 0.67, 0.05, 0.87, 0.18, 0.52, 0.44, 0.96, 0.53, 0.1, 0.31, 0.14, 0.11, 0.03, 0.69, 0.75, 0.12, 0.38, 0.06, 0.14, 0.75, 0.05, 0.56, 0.68, 0.1, 0.78, 0.47, 0.27, 0.79, 0.22, 0.34, 0.88, 0.59, 0.48, 0.81, 0.66, 0.58, 0.76, 0.35, 0.81, 0.48, 0.58, 0.73, 0.43, 0.46, 0.64, 0.49, 0.45, 0.33, 0.62, 0.82, 0.85, 0.28, 0.58, 0.65, 0.85, 0.55, 0.52, 0.68, 0.49, 0.46, 0.39, 0.67, 0.66, 0.4, 0.78, 0.87, 0.79, 0.65, 0.92, 0.91, 0.94, 0.94, 0.99, 0.93, 0.96, 0.95, 0.95, 0.94, 0.81, 1.0, 0.96, 0.94, 1.0, 0.96, 0.99, 0.97, 0.97, 0.97, 1.0, 0.98, 0.96, 0.98, 0.75, 0.78, 0.9, 0.47, 0.91, 0.97, 0.49, 0.61, 0.51, 0.65, 0.5, 0.13, 0.5, 0.72, 0.42, 0.34, 0.48, 0.75, 0.53, 0.08, 0.62, 0.64, 0.25, 0.31, 0.14, 0.53, 0.01, 0.34, 0.15, 0.54, 0.56, 0.77, 0.39, 0.11, 0.51, 0.26, 0.04, 0.35, 0.31, 0.0, 0.58, 0.46, 0.01, 0.25, 0.63, 0.08, 0.0, 0.65, 0.12, 0.0, 0.23, 0.57, 0.04, 0.0, 0.61, 0.71, 0.29, 0.83, 0.54, 0.63, 0.47, 0.03, 0.26, 0.08, 0.81, 0.36, 0.0, 0.05, 0.56, 0.52, 0.01, 0.32, 0.79, 0.54, 0.19, 0.87, 0.44, 0.97, 0.11, 0.49, 0.56, 0.45, 0.44, 0.0, 0.42, 0.57, 0.05, 0.02, 0.41, 0.03, 0.01, 0.18, 0.64, 0.15, 0.02, 0.57, 0.75, 0.04, 0.01, 0.29, 0.3, 0.45, 0.83, 0.57, 0.98, 0.97, 0.5, 0.24, 0.34, 0.0, 0.5, 0.07, 0.43, 0.4, 0.81, 0.23, 0.57, 0.23, 0.57, 0.57, 0.05, 0.27, 0.52, 0.37, 0.02, 0.31, 0.69, 0.23, 0.08, 0.71, 0.46, 0.26, 0.38, 0.59, 0.6]
RING finger
Component of a SCF(SKP2)-like complex containing CUL1, SKP1, TRIM21 and SKP2.
SCF
null
IRF8, CALR, CUL1, FBXW11, HSPA5, IKBKB, IRF3, SKP1 , VCP,SKP2, DCP2 ,ULK1, BECN1,GABARAP, GABARAPL1, GABARAPL2 , MAP1LC3C,SQSTM1,IRF3 , NMI, IFI35 , CUL1, TRIM21
USP4, IKBKB, TRIM21, CDKN1B, IRF3, IRF8, MNI
mono, 63
null
UBE2D2, UBE2D1, UBE2E1, UBE2E2
Homotrimer
null
90.718042
0.406716
73.81348
0.576026
1,214
P19812
P16658
32118579
UbiNet, UbiBrowser
UBR1
MSVADDDLGSLQGHIRRTLRSIHNLPYFRYTRGPTERADMSRALKEFIYRYLYFVISNSGENLPTLFNAHPKQKLSNPELTVFPDSLEDAVDIDKITSQQTIPFYKIDESRIGDVHKHTGRNCGRKFKIGEPLYRCHECGCDDTCVLCIHCFNPKDHVNHHVCTDICTEFTSGICDCGDEEAWNSPLHCKAEEQENDISEDPATNADIKEEDVWNDSVNIALVELVLAEVFDYFIDVFNQNIEPLPTIQKDITIKLREMTQQGKMYERAQFLNDLKYENDYMFDGTTTAKTSPSNSPEASPSLAKIDPENYTVIIYNDEYHNYSQATTALRQGVPDNVHIDLLTSRIDGEGRAMLKCSQDLSSVLGGFFAVQTNGLSATLTSWSEYLHQETCKYIILWITHCLNIPNSSFQTTFRNMMGKTLCSEYLNATECRDMTPVVEKYFSNKFDKNDPYRYIDLSILADGNQIPLGHHKILPESSTHSLSPLINDVETPTSRTYSNTRLQHILYFDNRYWKRLRKDIQNVIIPTLASSNLYKPIFCQQVVEIFNHITRSVAYMDREPQLTAIRECVVQLFTCPTNAKNIFENQSFLDIVWSIIDIFKEFCKVEGGVLIWQRVQKSNLTKSYSISFKQGLYTVETLLSKVHDPNIPLRPKEIISLLTLCKLFNGAWKIKRKEGEHVLHEDQNFISYLEYTTSIYSIIQTAEKVSEKSKDSIDSKLFLNAIRIISSFLGNRSLTYKLIYDSHEVIKFSVSHERVAFMNPLQTMLSFLIEKVSLKDAYEALEDCSDFLKISDFSLRSVVLCSQIDVGFWVRNGMSVLHQASYYKNNPELGSYSRDIHLNQLAILWERDDIPRIIYNILDRWELLDWFTGEVDYQHTVYEDKISFIIQQFIAFIYQILTERQYFKTFSSLKDRRMDQIKNSIIYNLYMKPLSYSKLLRSVPDYLTEDTTEFDEALEEVSVFVEPKGLADNGVFKLKASLYAKVDPLKLLNLENEFESSATIIKSHLAKDKDEIAKVVLIPQVSIKQLDKDALNLGAFTRNTVFAKVVYKLLQVCLDMEDSTFLNELLHLVHGIFRDDELINGKDSIPEAYLSKPICNLLLSIANAKSDVFSESIVRKADYLLEKMIMKKPNELFESLIASFGNQYVNDYKDKKLRQGVNLQETEKERKRRLAKKHQARLLAKFNNQQTKFMKEHESEFDEQDNDVDMVGEKVYESEDFTCALCQDSSSTDFFVIPAYHDHSPIFRPGNIFNPNEFMPMWDGFYNDDEKQAYIDDDVLEALKENGSCGSRKVFVSCNHHIHHNCFKRYVQKKRFSSNAFICPLCQTFSNCTLPLCQTSKANTGLSLDMFLESELSLDTLSRLFKPFTEENYRTINSIFSLMISQCQGFDKAVRKRANFSHKDVSLILSVHWANTISMLEIASRLEKPYSISFFRSREQKYKTLKNILVCIMLFTFVIGKPSMEFEPYPQQPDTVWNQNQLFQYIVRSALFSPVSLRQTVTEALTTFSRQFLRDFLQGLSDAEQVTKLYAKASKIGDVLKVSEQMLFALRTISDVRMEGLDSESIIYDLAYTFLLKSLLPTIRRCLVFIKVLHELVKDSENETLVINGHEVEEELEFEDTAEFVNKALKMITEKESLVDLLTTQESIVSHPYLENIPYEYCGIIKLIDLSKYLNTYVTQSKEIKLREERSQHMKNADNRLDFKICLTCGVKVHLRADRHEMTKHLNKNCFKPFGAFLMPNSSEVCLHLTQPPSNIFISAPYLNSHGEVGRNAMRRGDLTTLNLKRYEHLNRLWINNEIPGYISRVMGDEFRVTILSNGFLFAFNREPRPRRIPPTDEDDEDMEEGEDGFFTEGNDEMDVDDETGQAANLFGVGAEGIAGGGVRDFFQFFENFRNTLQPQGNGDDDAPQNPPPILQFLGPQFDGATIIRNTNPRNLDEDDSDDNDDSDEREIW
Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
null
Not found
{}
3NIH, 3NII, 3NIJ, 3NIK, 3NIL, 3NIM, 3NIN, 3NIS, 3NIT, 6KGI, 7MEX, 7MEY
{}
SEN2
MSKGRVNQKRYKYPLPIHPVDDLPELILHNPLSWLYWAYRYYKSTNALNDKVHVDFIGDTTLHITVQDDKQMLYLWNNGFFGTGQFSRSEPTWKARTEARLGLNDTPLHNRGGTKSNTETEMTLEKVTQQRRLQRLEFKKERAKLERELLELRKKGGHIDEENILLEKQRESLRKFKLKQTEDVGIVAQQQDISESNLRDEDNNLLDENGDLLPLESLELMPVEAMFLTFALPVLDISPACLAGKLFQFDAKYKDIHSFVRSYVIYHHYRSHGWCVRSGIKFGCDYLLYKRGPPFQHAEFCVMGLDHDVSKDYTWYSSIARVVGGAKKTFVLCYVERLISEQEAIALWKSNNFTKLFNSFQVGEVLYKRWVPGRNRD
Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
Nucleus, Endomembrane system, Mitochondrion outer membrane
Not found
{}
null
{}
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[38.6, 53.92, 52.24, 58.07, 64.22, 78.48, 84.64, 85.24, 85.58, 87.54, 91.15, 89.2, 91.1, 91.21, 93.03, 91.7, 84.87, 85.26, 77.67, 78.63, 72.32, 77.12, 85.46, 87.22, 89.43, 90.92, 94.02, 94.0, 93.72, 95.22, 94.24, 94.57, 94.63, 95.37, 94.89, 93.55, 93.98, 92.32, 92.43, 90.53, 89.17, 88.72, 87.2, 84.73, 81.2, 79.0, 77.2, 81.93, 78.14, 86.91, 93.43, 96.42, 97.22, 97.23, 96.32, 95.23, 92.15, 86.82, 79.92, 80.02, 84.33, 92.12, 95.44, 97.52, 97.18, 96.97, 94.19, 94.31, 92.04, 92.78, 95.31, 95.42, 93.19, 94.35, 95.92, 95.17, 94.04, 93.74, 94.35, 96.24, 97.02, 95.69, 94.04, 91.91, 89.49, 88.21, 83.0, 80.21, 85.87, 89.66, 89.18, 87.67, 89.96, 88.01, 84.86, 83.21, 85.25, 85.05, 81.67, 82.67, 80.75, 75.39, 74.89, 64.26, 55.61, 44.13, 39.09, 36.53, 34.54, 32.49, 29.57, 24.79, 25.41, 26.54, 28.11, 31.63, 31.85, 37.17, 39.4, 44.07, 45.16, 53.13, 59.49, 63.24, 64.91, 69.19, 72.06, 72.63, 76.11, 79.03, 81.2, 83.45, 85.76, 84.92, 86.48, 90.32, 88.54, 88.02, 91.82, 92.95, 89.52, 89.86, 94.11, 92.95, 90.72, 90.73, 92.75, 89.85, 89.88, 88.97, 91.67, 89.07, 88.22, 90.02, 90.81, 87.05, 81.04, 86.08, 85.83, 86.66, 85.85, 86.28, 88.94, 90.62, 88.75, 88.9, 90.44, 90.13, 91.19, 90.51, 91.06, 89.27, 89.99, 89.96, 90.38, 86.49, 85.43, 86.89, 85.83, 82.1, 76.91, 78.51, 70.45, 64.72, 58.7, 55.82, 52.02, 51.11, 48.61, 50.24, 47.79, 45.48, 46.38, 48.57, 50.26, 54.01, 59.11, 66.67, 80.5, 79.46, 81.64, 82.96, 83.17, 87.26, 87.17, 86.77, 87.12, 85.86, 83.28, 81.23, 84.54, 86.48, 88.34, 86.16, 89.79, 92.34, 94.52, 96.44, 96.26, 97.78, 97.02, 96.99, 98.18, 98.42, 98.44, 98.03, 98.45, 97.88, 96.26, 96.38, 95.87, 93.86, 91.7, 95.64, 96.98, 95.87, 96.12, 96.36, 96.9, 96.17, 96.26, 96.45, 95.54, 94.27, 94.01, 93.98, 93.75, 88.68, 86.34, 90.43, 92.07, 95.2, 95.69, 95.42, 94.37, 96.2, 97.15, 96.23, 97.68, 98.52, 98.35, 98.64, 98.78, 98.76, 98.82, 98.81, 98.54, 98.54, 98.62, 97.42, 96.12, 96.47, 95.89, 97.95, 97.42, 98.35, 96.96, 96.2, 95.82, 93.79, 90.6, 93.98, 93.67, 96.44, 97.92, 98.69, 98.1, 98.47, 97.5, 94.22, 91.01, 92.14, 91.72, 88.62, 90.4, 90.75, 93.28, 96.01, 96.03, 97.78, 98.25, 98.55, 97.9, 97.76, 97.61, 97.89, 95.27, 93.26, 93.72, 89.39, 93.39, 94.39, 90.46, 93.27, 93.68, 91.49, 90.47, 92.34, 92.9, 91.92, 91.03, 93.4, 94.47, 90.51, 90.74, 91.08, 92.69, 94.55, 95.76, 96.77, 97.8, 97.24, 98.48, 98.36, 98.53, 98.29, 97.5, 98.16, 97.72, 97.6, 97.07, 96.95, 97.78, 97.9, 97.11, 97.46, 97.98, 96.93, 95.35, 96.08, 95.53, 97.26, 97.62, 97.79, 97.98, 98.52, 98.25, 97.89, 98.15, 98.5, 98.18, 98.49, 97.66, 97.67, 95.51, 94.88, 91.77, 83.8, 77.9, 79.1, 76.7, 79.62, 82.22, 74.12, 76.17, 77.55, 60.37]
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null
null
null
null
null
null
null
null
null
null
null
80.206826
0.307764
86.18061
0.420398
2,062
P19812
P38147
nan, 28515311, nan
degron_data, Degronopedia, degron_data
UBR1
MSVADDDLGSLQGHIRRTLRSIHNLPYFRYTRGPTERADMSRALKEFIYRYLYFVISNSGENLPTLFNAHPKQKLSNPELTVFPDSLEDAVDIDKITSQQTIPFYKIDESRIGDVHKHTGRNCGRKFKIGEPLYRCHECGCDDTCVLCIHCFNPKDHVNHHVCTDICTEFTSGICDCGDEEAWNSPLHCKAEEQENDISEDPATNADIKEEDVWNDSVNIALVELVLAEVFDYFIDVFNQNIEPLPTIQKDITIKLREMTQQGKMYERAQFLNDLKYENDYMFDGTTTAKTSPSNSPEASPSLAKIDPENYTVIIYNDEYHNYSQATTALRQGVPDNVHIDLLTSRIDGEGRAMLKCSQDLSSVLGGFFAVQTNGLSATLTSWSEYLHQETCKYIILWITHCLNIPNSSFQTTFRNMMGKTLCSEYLNATECRDMTPVVEKYFSNKFDKNDPYRYIDLSILADGNQIPLGHHKILPESSTHSLSPLINDVETPTSRTYSNTRLQHILYFDNRYWKRLRKDIQNVIIPTLASSNLYKPIFCQQVVEIFNHITRSVAYMDREPQLTAIRECVVQLFTCPTNAKNIFENQSFLDIVWSIIDIFKEFCKVEGGVLIWQRVQKSNLTKSYSISFKQGLYTVETLLSKVHDPNIPLRPKEIISLLTLCKLFNGAWKIKRKEGEHVLHEDQNFISYLEYTTSIYSIIQTAEKVSEKSKDSIDSKLFLNAIRIISSFLGNRSLTYKLIYDSHEVIKFSVSHERVAFMNPLQTMLSFLIEKVSLKDAYEALEDCSDFLKISDFSLRSVVLCSQIDVGFWVRNGMSVLHQASYYKNNPELGSYSRDIHLNQLAILWERDDIPRIIYNILDRWELLDWFTGEVDYQHTVYEDKISFIIQQFIAFIYQILTERQYFKTFSSLKDRRMDQIKNSIIYNLYMKPLSYSKLLRSVPDYLTEDTTEFDEALEEVSVFVEPKGLADNGVFKLKASLYAKVDPLKLLNLENEFESSATIIKSHLAKDKDEIAKVVLIPQVSIKQLDKDALNLGAFTRNTVFAKVVYKLLQVCLDMEDSTFLNELLHLVHGIFRDDELINGKDSIPEAYLSKPICNLLLSIANAKSDVFSESIVRKADYLLEKMIMKKPNELFESLIASFGNQYVNDYKDKKLRQGVNLQETEKERKRRLAKKHQARLLAKFNNQQTKFMKEHESEFDEQDNDVDMVGEKVYESEDFTCALCQDSSSTDFFVIPAYHDHSPIFRPGNIFNPNEFMPMWDGFYNDDEKQAYIDDDVLEALKENGSCGSRKVFVSCNHHIHHNCFKRYVQKKRFSSNAFICPLCQTFSNCTLPLCQTSKANTGLSLDMFLESELSLDTLSRLFKPFTEENYRTINSIFSLMISQCQGFDKAVRKRANFSHKDVSLILSVHWANTISMLEIASRLEKPYSISFFRSREQKYKTLKNILVCIMLFTFVIGKPSMEFEPYPQQPDTVWNQNQLFQYIVRSALFSPVSLRQTVTEALTTFSRQFLRDFLQGLSDAEQVTKLYAKASKIGDVLKVSEQMLFALRTISDVRMEGLDSESIIYDLAYTFLLKSLLPTIRRCLVFIKVLHELVKDSENETLVINGHEVEEELEFEDTAEFVNKALKMITEKESLVDLLTTQESIVSHPYLENIPYEYCGIIKLIDLSKYLNTYVTQSKEIKLREERSQHMKNADNRLDFKICLTCGVKVHLRADRHEMTKHLNKNCFKPFGAFLMPNSSEVCLHLTQPPSNIFISAPYLNSHGEVGRNAMRRGDLTTLNLKRYEHLNRLWINNEIPGYISRVMGDEFRVTILSNGFLFAFNREPRPRRIPPTDEDDEDMEEGEDGFFTEGNDEMDVDDETGQAANLFGVGAEGIAGGGVRDFFQFFENFRNTLQPQGNGDDDAPQNPPPILQFLGPQFDGATIIRNTNPRNLDEDDSDDNDDSDEREIW
Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
null
Not found
{}
3NIH, 3NII, 3NIJ, 3NIK, 3NIL, 3NIM, 3NIN, 3NIS, 3NIT, 6KGI, 7MEX, 7MEY
{}
CHK1
MSLSQVSPLPHIKDVVLGDTVGQGAFACVKNAHLQMDPSIILAVKFIHVPTCKKMGLSDKDITKEVVLQSKCSKHPNVLRLIDCNVSKEYMWIILEMADGGDLFDKIEPDVGVDSDVAQFYFQQLVSAINYLHVECGVAHRDIKPENILLDKNGNLKLADFGLASQFRRKDGTLRVSMDQRGSPPYMAPEVLYSEEGYYADRTDIWSIGILLFVLLTGQTPWELPSLENEDFVFFIENDGNLNWGPWSKIEFTHLNLLRKILQPDPNKRVTLKALKLHPWVLRRASFSGDDGLCNDPELLAKKLFSHLKVSLSNENYLKFTQDTNSNNRYISTQPIGNELAELEHDSMHFQTVSNTQRAFTSYDSNTNYNSGTGMTQEAKWTQFISYDIAALQFHSDENDCNELVKRHLQFNPNKLTKFYTLQPMDVLLPILEKALNLSQIRVKPDLFANFERLCELLGYDNVFPLIINIKTKSNGGYQLCGSISIIKIEEELKSVGFERKTGDPLEWRRLFKKISTICRDIILIPN
Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
Nucleus
Not found
{}
null
{}
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null
null
null
null
null
null
null
null
null
null
null
80.206826
0.307764
84.068292
0.310816
1,489
P19812
P41817
22199232
UbiNet, UbiBrowser
UBR1
MSVADDDLGSLQGHIRRTLRSIHNLPYFRYTRGPTERADMSRALKEFIYRYLYFVISNSGENLPTLFNAHPKQKLSNPELTVFPDSLEDAVDIDKITSQQTIPFYKIDESRIGDVHKHTGRNCGRKFKIGEPLYRCHECGCDDTCVLCIHCFNPKDHVNHHVCTDICTEFTSGICDCGDEEAWNSPLHCKAEEQENDISEDPATNADIKEEDVWNDSVNIALVELVLAEVFDYFIDVFNQNIEPLPTIQKDITIKLREMTQQGKMYERAQFLNDLKYENDYMFDGTTTAKTSPSNSPEASPSLAKIDPENYTVIIYNDEYHNYSQATTALRQGVPDNVHIDLLTSRIDGEGRAMLKCSQDLSSVLGGFFAVQTNGLSATLTSWSEYLHQETCKYIILWITHCLNIPNSSFQTTFRNMMGKTLCSEYLNATECRDMTPVVEKYFSNKFDKNDPYRYIDLSILADGNQIPLGHHKILPESSTHSLSPLINDVETPTSRTYSNTRLQHILYFDNRYWKRLRKDIQNVIIPTLASSNLYKPIFCQQVVEIFNHITRSVAYMDREPQLTAIRECVVQLFTCPTNAKNIFENQSFLDIVWSIIDIFKEFCKVEGGVLIWQRVQKSNLTKSYSISFKQGLYTVETLLSKVHDPNIPLRPKEIISLLTLCKLFNGAWKIKRKEGEHVLHEDQNFISYLEYTTSIYSIIQTAEKVSEKSKDSIDSKLFLNAIRIISSFLGNRSLTYKLIYDSHEVIKFSVSHERVAFMNPLQTMLSFLIEKVSLKDAYEALEDCSDFLKISDFSLRSVVLCSQIDVGFWVRNGMSVLHQASYYKNNPELGSYSRDIHLNQLAILWERDDIPRIIYNILDRWELLDWFTGEVDYQHTVYEDKISFIIQQFIAFIYQILTERQYFKTFSSLKDRRMDQIKNSIIYNLYMKPLSYSKLLRSVPDYLTEDTTEFDEALEEVSVFVEPKGLADNGVFKLKASLYAKVDPLKLLNLENEFESSATIIKSHLAKDKDEIAKVVLIPQVSIKQLDKDALNLGAFTRNTVFAKVVYKLLQVCLDMEDSTFLNELLHLVHGIFRDDELINGKDSIPEAYLSKPICNLLLSIANAKSDVFSESIVRKADYLLEKMIMKKPNELFESLIASFGNQYVNDYKDKKLRQGVNLQETEKERKRRLAKKHQARLLAKFNNQQTKFMKEHESEFDEQDNDVDMVGEKVYESEDFTCALCQDSSSTDFFVIPAYHDHSPIFRPGNIFNPNEFMPMWDGFYNDDEKQAYIDDDVLEALKENGSCGSRKVFVSCNHHIHHNCFKRYVQKKRFSSNAFICPLCQTFSNCTLPLCQTSKANTGLSLDMFLESELSLDTLSRLFKPFTEENYRTINSIFSLMISQCQGFDKAVRKRANFSHKDVSLILSVHWANTISMLEIASRLEKPYSISFFRSREQKYKTLKNILVCIMLFTFVIGKPSMEFEPYPQQPDTVWNQNQLFQYIVRSALFSPVSLRQTVTEALTTFSRQFLRDFLQGLSDAEQVTKLYAKASKIGDVLKVSEQMLFALRTISDVRMEGLDSESIIYDLAYTFLLKSLLPTIRRCLVFIKVLHELVKDSENETLVINGHEVEEELEFEDTAEFVNKALKMITEKESLVDLLTTQESIVSHPYLENIPYEYCGIIKLIDLSKYLNTYVTQSKEIKLREERSQHMKNADNRLDFKICLTCGVKVHLRADRHEMTKHLNKNCFKPFGAFLMPNSSEVCLHLTQPPSNIFISAPYLNSHGEVGRNAMRRGDLTTLNLKRYEHLNRLWINNEIPGYISRVMGDEFRVTILSNGFLFAFNREPRPRRIPPTDEDDEDMEEGEDGFFTEGNDEMDVDDETGQAANLFGVGAEGIAGGGVRDFFQFFENFRNTLQPQGNGDDDAPQNPPPILQFLGPQFDGATIIRNTNPRNLDEDDSDDNDDSDEREIW
Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
null
Not found
{}
3NIH, 3NII, 3NIJ, 3NIK, 3NIL, 3NIM, 3NIN, 3NIS, 3NIT, 6KGI, 7MEX, 7MEY
{}
CUP9
MNYNCEIQNRNSKNVDNQVSLPPIQVLFNSIEKRSMPELAFSNIEYSHGNLRSSTEEQNYPAPVLLPQHHSIAYPAINSGGTSTTATPTASTVETSKTSSSAMDTQSQYGSSKKSKSASDDAKPCYKSAPIYEIINKEKDAGAQYNRPFSDFVESKSRRKQNSGRRSNLPKETVQILNTWLLNHLNNPYPTQQEKRELLIKTGLTKIQLSNWFINVRRRKIFSDYYTLVNSIPNDNANNTPVERVQNVSAYHNTLSATNNTMYDATSTCSTDYELSKRFAHAPVTRRKKLIDRLEELKKLSNPDMN
Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
Nucleus
Not found
{}
null
{}
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0.61, 0.53, 0.48, 0.58, 0.43, 0.54, 0.58, 0.76, 0.7, 0.73, 0.88, 0.95, 0.86, 1.0, 0.97, 0.99, 1.0, 0.99, 1.0, 0.95, 1.0, 0.9, 0.81, 0.69, 0.7, 0.62, 0.64, 0.79, 0.85, 0.68, 0.86, 0.78, 0.84, 0.77, 0.91, 0.79, 0.81, 0.89, 0.68, 0.78, 0.73, 0.84, 0.65, 0.63, 0.83, 0.85, 0.67, 0.81, 0.81, 0.72, 0.95, 0.87, 0.74, 0.96, 0.71, 0.84, 0.64, 0.95, 0.83, 0.97, 0.84, 0.82, 0.97, 1.0, 0.97]
[45.25, 43.08, 55.56, 44.39, 53.05, 50.98, 47.24, 50.47, 43.21, 45.43, 41.8, 40.37, 43.64, 42.1, 46.07, 44.17, 48.66, 49.12, 54.16, 68.91, 71.73, 78.31, 81.22, 75.85, 76.96, 75.9, 68.31, 70.56, 67.85, 67.36, 59.17, 59.92, 59.98, 50.75, 46.56, 49.95, 53.08, 48.92, 45.21, 46.67, 38.23, 44.7, 39.05, 43.85, 38.03, 34.43, 38.23, 42.1, 40.35, 34.06, 39.14, 36.16, 34.74, 39.93, 38.51, 43.55, 38.66, 40.31, 43.94, 42.44, 51.35, 43.09, 56.34, 56.14, 38.3, 41.51, 45.93, 38.73, 47.64, 48.47, 43.03, 48.97, 43.99, 52.34, 53.51, 41.63, 51.85, 42.54, 45.11, 39.06, 39.91, 45.6, 38.89, 46.19, 38.53, 45.6, 41.52, 48.41, 42.41, 40.18, 46.52, 45.2, 54.28, 43.5, 41.34, 54.19, 48.85, 44.28, 49.63, 50.13, 41.51, 41.83, 56.97, 43.16, 44.94, 50.18, 43.39, 40.9, 41.23, 38.09, 38.68, 43.69, 44.17, 41.19, 41.41, 44.36, 39.23, 42.73, 49.73, 47.36, 50.29, 48.85, 54.93, 42.84, 42.34, 39.83, 52.02, 54.37, 57.76, 60.47, 57.01, 51.33, 51.46, 56.29, 57.55, 56.67, 54.07, 51.73, 48.91, 46.0, 45.3, 42.48, 44.5, 49.12, 44.86, 44.09, 46.81, 45.24, 38.84, 50.4, 41.62, 45.99, 53.34, 41.83, 49.77, 49.39, 52.26, 55.94, 54.19, 56.96, 58.1, 54.66, 58.74, 59.83, 57.59, 73.19, 78.78, 89.89, 91.71, 93.99, 93.72, 94.75, 95.78, 94.99, 95.08, 95.94, 96.64, 93.24, 93.84, 95.03, 93.29, 89.54, 91.4, 91.19, 87.83, 86.12, 89.97, 93.38, 95.94, 95.78, 96.75, 96.02, 96.59, 97.2, 97.12, 96.92, 97.36, 97.56, 97.47, 96.77, 96.57, 96.44, 95.82, 95.78, 96.38, 96.42, 95.96, 96.28, 97.2, 96.46, 96.19, 96.37, 96.42, 94.41, 94.45, 92.56, 93.32, 90.18, 88.59, 80.24, 75.75, 71.06, 66.87, 59.78, 60.55, 54.65, 58.53, 54.63, 60.67, 51.88, 59.19, 55.52, 50.37, 49.86, 43.76, 42.73, 41.6, 37.49, 41.82, 44.97, 35.63, 44.48, 41.17, 43.08, 44.93, 42.18, 41.73, 43.28, 42.88, 48.31, 39.76, 41.68, 41.12, 48.19, 43.07, 41.66, 37.17, 42.49, 44.55, 44.95, 49.19, 40.32, 50.08, 40.38, 52.48, 53.92, 51.94, 52.1, 50.17, 60.83, 74.2, 76.83, 84.11, 78.69, 75.49, 79.88, 81.72, 80.66, 82.76, 78.23, 80.96, 80.76, 82.7, 83.02, 87.68, 86.24, 89.3, 88.69, 91.95, 91.77, 91.89, 91.27, 93.31, 93.59, 91.61, 91.23, 90.86, 89.13, 87.62, 83.57, 84.31, 76.16, 71.6, 69.91, 61.82, 54.6]
[0.95, 0.99, 0.89, 0.92, 0.87, 0.86, 0.92, 0.71, 0.84, 0.84, 0.89, 1.0, 1.0, 1.0, 0.91, 0.89, 0.84, 0.85, 0.82, 0.87, 0.88, 0.66, 0.68, 0.64, 0.7, 0.49, 0.56, 0.57, 0.61, 0.56, 0.67, 0.8, 0.85, 0.78, 0.85, 0.86, 0.84, 0.93, 0.82, 0.87, 0.88, 0.85, 0.93, 0.93, 0.97, 0.92, 0.98, 0.92, 0.96, 0.99, 0.98, 0.99, 0.98, 0.97, 0.98, 0.97, 1.0, 0.85, 0.99, 0.95, 0.95, 0.94, 0.94, 0.96, 0.98, 0.99, 0.86, 1.0, 0.9, 0.9, 0.98, 0.8, 0.96, 0.92, 0.94, 0.93, 0.95, 0.98, 0.98, 1.0, 1.0, 1.0, 0.96, 0.99, 0.98, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 0.97, 1.0, 0.97, 1.0, 0.99, 1.0, 1.0, 1.0, 0.93, 1.0, 0.97, 1.0, 1.0, 1.0, 0.93, 1.0, 0.98, 1.0, 0.99, 0.98, 0.99, 0.96, 0.98, 0.95, 1.0, 0.99, 1.0, 1.0, 1.0, 0.98, 0.97, 0.9, 0.93, 0.96, 0.95, 0.97, 0.52, 0.49, 0.69, 0.71, 0.63, 0.72, 0.78, 0.84, 0.84, 0.96, 1.0, 0.99, 0.98, 0.95, 0.98, 1.0, 0.99, 0.99, 0.99, 0.91, 0.99, 0.89, 0.95, 0.85, 0.94, 0.92, 0.85, 0.94, 0.99, 0.98, 0.95, 0.91, 1.0, 0.84, 0.84, 0.95, 0.87, 0.95, 0.88, 0.92, 0.32, 0.59, 0.85, 0.72, 0.08, 0.29, 0.66, 0.3, 0.0, 0.27, 0.51, 0.13, 0.06, 0.66, 0.79, 0.33, 0.37, 0.87, 0.6, 0.07, 0.59, 0.26, 0.54, 0.65, 0.5, 0.18, 0.18, 0.53, 0.42, 0.05, 0.22, 0.81, 0.64, 0.12, 0.76, 0.15, 0.57, 0.6, 0.71, 0.44, 0.0, 0.33, 0.53, 0.16, 0.05, 0.34, 0.39, 0.04, 0.2, 0.7, 0.64, 0.52, 0.07, 0.69, 0.68, 0.59, 0.19, 0.69, 0.62, 0.73, 0.64, 0.75, 0.58, 0.77, 0.78, 0.82, 0.87, 0.82, 0.98, 1.0, 1.0, 0.97, 1.0, 0.95, 0.94, 0.98, 0.92, 0.97, 0.89, 0.99, 0.87, 0.89, 0.98, 0.95, 0.39, 0.98, 0.96, 0.99, 0.39, 0.72, 0.91, 0.98, 0.73, 0.98, 0.78, 0.7, 0.55, 0.78, 0.88, 0.89, 0.75, 0.38, 0.51, 0.76, 0.71, 0.42, 0.44, 0.56, 0.61, 0.69, 0.66, 0.71, 0.87, 0.47, 0.88, 0.49, 0.65, 0.78, 0.77, 0.47, 0.6, 0.51, 0.38, 0.37, 0.66, 0.61, 0.52, 0.59, 0.54, 0.68, 0.71, 0.7, 0.72, 0.56, 0.75, 0.95, 0.85, 0.94]
null
null
null
null
null
null
null
null
null
null
null
80.206826
0.307764
60.616569
0.773072
2,361
P19812
Q12158
null
degron_data
UBR1
MSVADDDLGSLQGHIRRTLRSIHNLPYFRYTRGPTERADMSRALKEFIYRYLYFVISNSGENLPTLFNAHPKQKLSNPELTVFPDSLEDAVDIDKITSQQTIPFYKIDESRIGDVHKHTGRNCGRKFKIGEPLYRCHECGCDDTCVLCIHCFNPKDHVNHHVCTDICTEFTSGICDCGDEEAWNSPLHCKAEEQENDISEDPATNADIKEEDVWNDSVNIALVELVLAEVFDYFIDVFNQNIEPLPTIQKDITIKLREMTQQGKMYERAQFLNDLKYENDYMFDGTTTAKTSPSNSPEASPSLAKIDPENYTVIIYNDEYHNYSQATTALRQGVPDNVHIDLLTSRIDGEGRAMLKCSQDLSSVLGGFFAVQTNGLSATLTSWSEYLHQETCKYIILWITHCLNIPNSSFQTTFRNMMGKTLCSEYLNATECRDMTPVVEKYFSNKFDKNDPYRYIDLSILADGNQIPLGHHKILPESSTHSLSPLINDVETPTSRTYSNTRLQHILYFDNRYWKRLRKDIQNVIIPTLASSNLYKPIFCQQVVEIFNHITRSVAYMDREPQLTAIRECVVQLFTCPTNAKNIFENQSFLDIVWSIIDIFKEFCKVEGGVLIWQRVQKSNLTKSYSISFKQGLYTVETLLSKVHDPNIPLRPKEIISLLTLCKLFNGAWKIKRKEGEHVLHEDQNFISYLEYTTSIYSIIQTAEKVSEKSKDSIDSKLFLNAIRIISSFLGNRSLTYKLIYDSHEVIKFSVSHERVAFMNPLQTMLSFLIEKVSLKDAYEALEDCSDFLKISDFSLRSVVLCSQIDVGFWVRNGMSVLHQASYYKNNPELGSYSRDIHLNQLAILWERDDIPRIIYNILDRWELLDWFTGEVDYQHTVYEDKISFIIQQFIAFIYQILTERQYFKTFSSLKDRRMDQIKNSIIYNLYMKPLSYSKLLRSVPDYLTEDTTEFDEALEEVSVFVEPKGLADNGVFKLKASLYAKVDPLKLLNLENEFESSATIIKSHLAKDKDEIAKVVLIPQVSIKQLDKDALNLGAFTRNTVFAKVVYKLLQVCLDMEDSTFLNELLHLVHGIFRDDELINGKDSIPEAYLSKPICNLLLSIANAKSDVFSESIVRKADYLLEKMIMKKPNELFESLIASFGNQYVNDYKDKKLRQGVNLQETEKERKRRLAKKHQARLLAKFNNQQTKFMKEHESEFDEQDNDVDMVGEKVYESEDFTCALCQDSSSTDFFVIPAYHDHSPIFRPGNIFNPNEFMPMWDGFYNDDEKQAYIDDDVLEALKENGSCGSRKVFVSCNHHIHHNCFKRYVQKKRFSSNAFICPLCQTFSNCTLPLCQTSKANTGLSLDMFLESELSLDTLSRLFKPFTEENYRTINSIFSLMISQCQGFDKAVRKRANFSHKDVSLILSVHWANTISMLEIASRLEKPYSISFFRSREQKYKTLKNILVCIMLFTFVIGKPSMEFEPYPQQPDTVWNQNQLFQYIVRSALFSPVSLRQTVTEALTTFSRQFLRDFLQGLSDAEQVTKLYAKASKIGDVLKVSEQMLFALRTISDVRMEGLDSESIIYDLAYTFLLKSLLPTIRRCLVFIKVLHELVKDSENETLVINGHEVEEELEFEDTAEFVNKALKMITEKESLVDLLTTQESIVSHPYLENIPYEYCGIIKLIDLSKYLNTYVTQSKEIKLREERSQHMKNADNRLDFKICLTCGVKVHLRADRHEMTKHLNKNCFKPFGAFLMPNSSEVCLHLTQPPSNIFISAPYLNSHGEVGRNAMRRGDLTTLNLKRYEHLNRLWINNEIPGYISRVMGDEFRVTILSNGFLFAFNREPRPRRIPPTDEDDEDMEEGEDGFFTEGNDEMDVDDETGQAANLFGVGAEGIAGGGVRDFFQFFENFRNTLQPQGNGDDDAPQNPPPILQFLGPQFDGATIIRNTNPRNLDEDDSDDNDDSDEREIW
Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
null
Not found
{}
3NIH, 3NII, 3NIJ, 3NIK, 3NIL, 3NIM, 3NIN, 3NIS, 3NIT, 6KGI, 7MEX, 7MEY
{}
MCD1
MVTENPQRLTVLRLATNKGPLAQIWLASNMSNIPRGSVIQTHIAESAKEIAKASGCDDESGDNEYITLRTSGELLQGIVRVYSKQATFLLTDIKDTLTKISMLFKTSQKMTSTVNRLNTVTRVHQLMLEDAVTEREVLVTPGLEFLDDTTIPVGLMAQENSMERKVQGAAPWDTSLEVGRRFSPDEDFEHNNLSSMNLDFDIEEGPITSKSWEEGTRQSSRNFDTHENYIQDDDFPLDDAGTIGWDLGITEKNDQNNDDDDNSVEQGRRLGESIMSEEPTDFGFDLDIEKEAPAGNIDTITDAMTESQPKQTGTRRNSKLLNTKSIQIDEETENSESIASSNTYKEERSNNLLTPQPTNFTTKRLWSEITESMSYLPDPILKNFLSYESLKKRKIHNGREGSIEEPELNVSLNLTDDVISNAGTNDNSFNELTDNMSDFVPIDAGLNEAPFPEENIIDAKTRNEQTTIQTEKVRPTPGEVASKAIVQMAKILRKELSEEKEVIFTDVLKSQANTEPENITKREASRGFFDILSLATEGCIGLSQTEAFGNIKIDAKPALFERFINA
Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
Nucleus, Chromosome, Chromosome, centromere
Not found
{}
1W1W, 4UX3, 5FRP, 5FRS, 6H8Q, 6QPQ, 6QPW, 6ZZ6
{}
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null
null
null
null
null
null
null
null
null
null
null
80.206826
0.307764
57.434382
0.727049
1,371
P21461
P42282
22199232
UbiNet, UbiBrowser
sina
MSNKINPKRREPTAAAAGAGATGVATNTSTSTGSSSAGNTSSANTSSSSSSSLSSAGGGDAGMSADLTSLFECPVCFDYVLPPILQCSSGHLVCVSCRSKLTCCPTCRGPLANIRNLAMEKVASNVKFPCKHSGYGCTASLVYTEKTEHEETCECRPYLCPCPGASCKWQGPLDLVMQHLMMSHKSITTLQGEDIVFLATDINLPGAVDWVMMQSCFGHHFMLVLEKQEKYDGHQQFFAIVQLIGSRKEAENFVYRLELNGNRRRLTWEAMPRSIHEGVASAIHNSDCLVFDTSIAQLFADNGNLGINVTISLV
Drosophila melanogaster
Cytoplasm, Nucleus
Not found
{}
null
{}
ttk
MKMASQRFCLRWNNHQSNLLSVFDQLLHAETFTDVTLAVEGQHLKAHKMVLSACSPYFNTLFVSHPEKHPIVILKDVPYSDMKSLLDFMYRGEVSVDQERLTAFLRVAESLRIKGLTEVNDDKPSPAAAAAGAGATGSESTATTPQLQRIQPYLVPQRNRSQAGGLLASAANAGNTPTLPVQPSLLSSALMPKRKRGRPRKLSGSSNGTGNDYDDFDRENMMNDSSDLGNGKMCNESYSGNDDGSDDNQPNAGHTDDLNESRDSLPSKRSKNSKDHRVVSHHEDNSTSVTPTKATPELSQRLFGSSSTTISATAPGGSSTGPSETISLLEISDERESAPVHLPTILGLKIRAINTTTPAQQGSPQTPTKSKPKIRQATGSNNSNSLLKQQLRGGAKDPEVPPATRITGAVTPNAALNAEEQSKEMPKKNQDEVNACIGLHSLANAAEQQAAQVASTGNLHHQLLLHMAANNSMLNTTDYYQQQQQESPSSAGQFMDDDLELLSLNDQQDKSDEPDHEMVTLADENAGLPGYQGNEAEATPAQEDSPAAETATAPPPAPRSGKKGAKRPIQRRRVRRKAQSTLDDQAEHLTEMSVRGLDLFRYASVVEGVYRCTECAKENMQKTFKNKYSFQRHAFLYHEGKHRKVFPCPVCSKEFSRPDKMKNHLKMTHENFTPPKDIGAFSPLKYLISAAAAGDMHATIYQQQQDHYHRQLAEQLEQQNASFDSRDSSLILPDVKMEHAEDQDAEQEAELSDGGYDASNPAAAAAAMLSLQQDVIIKDEIQISPSPSPTPPASCAVAEGKSLALASTAQTAT
Drosophila melanogaster
Nucleus
Not found
{}
null
{}
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null
null
null
null
null
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82.362357
0.447803
53.060418
0.772079
781
P21580
P21580
21095585, E3Net
UbiNet, UbiBrowser, 31181401
TNFAIP3
MAEQVLPQALYLSNMRKAVKIRERTPEDIFKPTNGIIHHFKTMHRYTLEMFRTCQFCPQFREIIHKALIDRNIQATLESQKKLNWCREVRKLVALKTNGDGNCLMHATSQYMWGVQDTDLVLRKALFSTLKETDTRNFKFRWQLESLKSQEFVETGLCYDTRNWNDEWDNLIKMASTDTPMARSGLQYNSLEEIHIFVLCNILRRPIIVISDKMLRSLESGSNFAPLKVGGIYLPLHWPAQECYRYPIVLGYDSHHFVPLVTLKDSGPEIRAVPLVNRDRGRFEDLKVHFLTDPENEMKEKLLKEYLMVIEIPVQGWDHGTTHLINAAKLDEANLPKEINLVDDYFELVQHEYKKWQENSEQGRREGHAQNPMEPSVPQLSLMDVKCETPNCPFFMSVNTQPLCHECSERRQKNQNKLPKLNSKPGPEGLPGMALGASRGEAYEPLAWNPEESTGGPHSAPPTAPSPFLFSETTAMKCRSPGCPFTLNVQHNGFCERCHNARQLHASHAPDHTRHLDPGKCQACLQDVTRTFNGICSTCFKRTTAEASSSLSTSLPPSCHQRSKSDPSRLVRSPSPHSCHRAGNDAPAGCLSQAARTPGDRTGTSKCRKAGCVYFGTPENKGFCTLCFIEYRENKHFAAASGKVSPTASRFQNTIPCLGRECGTLGSTMFEGYCQKCFIEAQNQRFHEAKRTEEQLRSSQRRDVPRTTQSTSRPKCARASCKNILACRSEELCMECQHPNQRMGPGAHRGEPAPEDPPKQRCRAPACDHFGNAKCNGYCNECFQFKQMYG
Homo sapiens
Cytoplasm, Nucleus, Lysosome, Cytoplasm
Tissue enhanced (bone marrow, urinary bladder)
{'Ciliated cells': '222.0', 'Basal respiratory cells': '102.4', 'Club cells': '102.0', 'Ionocytes': '151.3', 'Mucus glandular cells': '266.5', 'Serous glandular cells': '115.3', 'Gastric mucus-secreting cells': '78.4', 'Proximal enterocytes': '42.9', 'Paneth cells': '17.5', 'Distal enterocytes': '30.6', 'Intestinal goblet cells': '32.1', 'Exocrine glandular cells': '-0.645', 'Basal prostatic cells': '87.8', 'Prostatic glandular cells': '11.6', 'Breast glandular cells': '0.196', 'Breast myoepithelial cells': '0.372', 'Glandular and luminal cells': '1464.3', 'Secretory cells': '239.6', 'Basal keratinocytes': '563.3', 'Suprabasal keratinocytes': '566.8', 'Basal squamous epithelial cells': '378.1', 'Squamous epithelial cells': '345.1', 'Alveolar cells type 1': '-0.009', 'Alveolar cells type 2': '-0.143', 'Salivary duct cells': '291.9', 'Ductal cells': '0.789', 'Hepatocytes': '0.134', 'Cholangiocytes': '21.0', 'Proximal tubular cells': '0.197', 'Distal tubular cells': '3.1', 'Collecting duct cells': '1.9', 'Mesothelial cells': '0.018', 'Sertoli cells': '0.075', 'Granulosa cells': '40.0', 'Enteroendocrine cells': '18.1', 'Pancreatic endocrine cells': '8.5', 'Leydig cells': '0.370', 'Excitatory neurons': '0.1', 'Inhibitory neurons': '0.3', 'Cone photoreceptor cells': '27.2', 'Rod photoreceptor cells': '15.7', 'Bipolar cells': '0.7', 'Horizontal cells': '1.9', 'Astrocytes': '1.9', 'Oligodendrocyte precursor cells': '1.9', 'Oligodendrocytes': '0.3', 'Microglial cells': '8.1', 'Muller glia cells': '5.5', 'Schwann cells': '0.011', 'Spermatogonia': '0.126', 'Spermatocytes': '-0.024', 'Early spermatids': '-0.035', 'Late spermatids': '-0.353', 'Oocytes': '5.1', 'Cytotrophoblasts': '8.5', 'Syncytiotrophoblasts': '19.6', 'Extravillous trophoblasts': '115.1', 'Endothelial cells': '144.9', 'Lymphatic endothelial cells': '37.6', 'Cardiomyocytes': '0.076', 'Skeletal myocytes': '0.359', 'Smooth muscle cells': '98.4', 'Adipocytes': '63.2', 'Melanocytes': '0.090', 'Fibroblasts': '83.8', 'Peritubular cells': '0.371', 'Endometrial stromal cells': '359.1', 'Ovarian stromal cells': '34.9', 'Undifferentiated cells': '12.6', 'T-cells': '778.2', 'B-cells': '95.4', 'Plasma cells': '280.9', 'Nk-cells': '411.5', 'Granulocytes': '1749.7', 'Monocytes': '1731.0', 'Macrophages': '777.5', 'Hofbauer cells': '176.5', 'Kupffer cells': '128.4', 'Dendritic cells': '129.5', 'Langerhans cells': '0.173', 'Erythroid cells': '0.154', 'Adipocytes (Subcutaneous)': '-0.425', 'Adipocytes (Visceral)': '-0.220', 'Breast glandular cells (progenitors)': '0.080', 'Adipocytes (Breast)': '-0.482', 'Colon enterocytes': '0.003', 'Colon enteroendocrine cells': '0.117', 'Enteric glia cells': '-0.193', 'Mitotic cells (Colon)': '0.097', 'Mitotic cells (Heart)': '0.354', 'Podocytes': '0.203', 'Ascending Loop of Henle cells': '0.015', 'Intercalated cells': '0.035', 'Cholangiocyte': '0.460', 'NK-cells (Liver)': '-0.192', 'Respiratory ciliated cells': '0.038', 'Mitotic cells (Lung)': '-0.111', 'NK-cells (Lung)': '0.178', 'B-cells (Lung)': '0.275', 'Alpha cells': '0.355', 'Beta cells': '0.236', 'Prostate glandular cells': '-0.177', 'Prostate basal glandular cells': '0.085', 'Urothelial cells': '0.154', 'Keratinocyte (other)': '0.355', 'Keratinocyte (granular)': '0.073', 'Hair cortex cells': '-0.229', 'Inner root sheath cells': '-0.173', 'Outer root sheath cells': '-0.203', 'Sebaceous gland cells': '-0.246', 'Eccrine sweat gland cells': '-0.219', 'Adipocytes (Skin)': '-0.360', 'Mitotic cells (Skin)': '0.009', 'Parietal cells': '-0.352', 'Chief cells': '-0.303', 'Gastric mucous cells': '-0.072', 'Gastric enteroendocrine cells': '-0.148', 'Mitotic cells (Stomach)': '0.111', 'Parafollicular cells': '0.005', 'Thyroid glandular cells': '-0.055', 'Mitotic cells (Thyroid)': '0.346', 'Adrenal cortex cells': '0.171', 'Adrenal medulla cells': '-0.001', 'Mitotic cells (Adrenal gland)': '-0.127', 'Minor salivary glandular cells': '0.610', 'Minor salivary gland ductal cells': '0.258', 'Minor salivary gland basal cells': '0.129', 'Mitotic cells (Minor salivary gland)': '0.169', 'Adipocytes (Minor salivary gland)': '0.167', 'Somatotropes': '-0.211', 'Lactotropes': '-0.389', 'Gonadotropes': '0.036', 'Corticotropes': '-0.232', 'Thyrotropes': '-0.083', 'Undifferentiated cells (Pituitary gland)': '0.183', 'Mitotic cells (Spleen)': '-0.149', 'Platelets': '-0.130', 'Erythrocytes': '-0.171', 'Hematopoietic stem cells': '-0.172', 'B-cells (Spleen)': '0.435', 'NK-cells (Spleen)': '0.215', 'Amygdala excitatory': '0.7', 'Cerebellar inhibitory': '2.7', 'Cge interneuron': '0.4', 'Deep-layer corticothalamic and 6b': '0.4', 'Deep-layer intratelencephalic': '0.5', 'Deep-layer near-projecting': '0.1', 'Eccentric medium spiny neuron': '0.5', 'Hippocampal ca1-3': '0.5', 'Hippocampal ca4': '1.3', 'Hippocampal dentate gyrus': '0.5', 'Lamp5-lhx6 and chandelier': '0.9', 'Lower rhombic lip': '1.3', 'Mammillary body': '0.2', 'Medium spiny neuron': '0.4', 'Mge interneuron': '0.1', 'Midbrain-derived inhibitory': '0.0', 'Miscellaneous': '0.2', 'Splatter': '1.2', 'Thalamic excitatory': '2.3', 'Upper rhombic lip': '0.1', 'Upper-layer intratelencephalic': '0.6', 'Astrocyte': '3.0', 'Bergmann glia': '2.5', 'Central nervous system macrophage': '24.4', 'Choroid plexus epithelial cell': '0.7', 'Committed oligodendrocyte precursor': '1.6', 'Ependymal cell': '2.1', 'Oligodendrocyte': '0.7', 'Oligodendrocyte precursor cell': '2.0', 'Endothelial cell': '51.5', 'Pericyte': '15.8', 'Vascular associated smooth muscle cell': '12.1', 'Fibroblast': '17.8', 'Leukocyte': '94.2', 'Basophil': '92.3', 'Eosinophil': '5.6', 'Neutrophil': '3039.7', 'Classical monocyte': '535.9', 'Non-classical monocyte': '75.6', 'Intermediate monocyte': '1330.1', 'T-reg': '572.8', 'GdT-cell': '11.5', 'MAIT T-cell': '1817.4', 'Memory CD4 T-cell': '11.1', 'Naive CD4 T-cell': '1624.2', 'Memory CD8 T-cell': '10.9', 'Naive CD8 T-cell': '1289.0', 'Memory B-cell': '4.6', 'Naive B-cell': '193.4', 'Plasmacytoid DC': '146.7', 'Myeloid DC': '771.0', 'NK-cell': '630.7', 'Total PBMC': '438.1', 'Vd2 gdTCR': '1321.8', 'Memory CD4 T-cell Th1\\/Th17': '4758.2', 'Memory CD4 T-cell Th17': '2777.6', 'Memory CD4 T-cell Th2': '2696.4', 'Non-Vd2 gdTCR': '697.3', 'Memory CD4 T-cell Th1': '3101.6', 'Memory CD4 T-cell TFH': '1767.2', 'Terminal effector memory CD4 T-cell': '586.0', 'Central memory CD8 T-cell': '1346.2', 'Effector memory CD8 T-cell': '1030.8', 'Terminal effector memory CD8 T-cell': '643.9', 'Non-switched memory B-cell': '183.3', 'Plasmablast': '108.3', 'Switched memory B-cell': '133.9', 'Exhausted memory B-cell': '184.7', 'Progenitor cell': '61.7', 'Memory T-reg': '1316.7', 'Naive CD4 T-cell activated': '1454.6', 'Naive CD8 T-cell activated': '1341.5', 'Naive T-reg': '813.0'}
2EQE, 2EQF, 2EQG, 2VFJ, 3DKB, 3OJ3, 3OJ4, 3VUW, 3VUX, 3VUY, 3ZJD, 3ZJE, 3ZJF, 3ZJG, 5LRX, 5V3B, 5V3P
{'Adipose Tissue': 71.89422425249168, 'Adrenal Gland': 18.808178294573644, 'Bladder': 27.82095238095238, 'Blood': 90.27551883745964, 'Blood Vessel': 22.304372284644195, 'Brain': 2.4634945495836487, 'Breast': 38.57104575163399, 'Cervix Uteri': 22.62152631578947, 'Colon': 29.911654685494224, 'Esophagus': 23.34145743944637, 'Fallopian Tube': 47.24111111111111, 'Heart': 12.724618118466898, 'Kidney': 16.023370786516853, 'Liver': 11.73166814159292, 'Lung': 103.90608996539792, 'Muscle': 5.374799252801993, 'Nerve': 35.55016155088853, 'Ovary': 131.08455555555557, 'Pancreas': 9.580134146341464, 'Pituitary': 13.757773851590104, 'Prostate': 30.354032653061225, 'Salivary Gland': 23.303753086419754, 'Skin': 55.29272028745163, 'Small Intestine': 50.19026737967914, 'Spleen': 57.31813278008299, 'Stomach': 21.495189415041786, 'Testis': 14.136614958448757, 'Thyroid': 23.792597243491574, 'Uterus': 30.784436619718313, 'Vagina': 27.45127564102564}
TNFAIP3
MAEQVLPQALYLSNMRKAVKIRERTPEDIFKPTNGIIHHFKTMHRYTLEMFRTCQFCPQFREIIHKALIDRNIQATLESQKKLNWCREVRKLVALKTNGDGNCLMHATSQYMWGVQDTDLVLRKALFSTLKETDTRNFKFRWQLESLKSQEFVETGLCYDTRNWNDEWDNLIKMASTDTPMARSGLQYNSLEEIHIFVLCNILRRPIIVISDKMLRSLESGSNFAPLKVGGIYLPLHWPAQECYRYPIVLGYDSHHFVPLVTLKDSGPEIRAVPLVNRDRGRFEDLKVHFLTDPENEMKEKLLKEYLMVIEIPVQGWDHGTTHLINAAKLDEANLPKEINLVDDYFELVQHEYKKWQENSEQGRREGHAQNPMEPSVPQLSLMDVKCETPNCPFFMSVNTQPLCHECSERRQKNQNKLPKLNSKPGPEGLPGMALGASRGEAYEPLAWNPEESTGGPHSAPPTAPSPFLFSETTAMKCRSPGCPFTLNVQHNGFCERCHNARQLHASHAPDHTRHLDPGKCQACLQDVTRTFNGICSTCFKRTTAEASSSLSTSLPPSCHQRSKSDPSRLVRSPSPHSCHRAGNDAPAGCLSQAARTPGDRTGTSKCRKAGCVYFGTPENKGFCTLCFIEYRENKHFAAASGKVSPTASRFQNTIPCLGRECGTLGSTMFEGYCQKCFIEAQNQRFHEAKRTEEQLRSSQRRDVPRTTQSTSRPKCARASCKNILACRSEELCMECQHPNQRMGPGAHRGEPAPEDPPKQRCRAPACDHFGNAKCNGYCNECFQFKQMYG
Homo sapiens
Cytoplasm, Nucleus, Lysosome, Cytoplasm
Tissue enhanced (bone marrow, urinary bladder)
{'Ciliated cells': '222.0', 'Basal respiratory cells': '102.4', 'Club cells': '102.0', 'Ionocytes': '151.3', 'Mucus glandular cells': '266.5', 'Serous glandular cells': '115.3', 'Gastric mucus-secreting cells': '78.4', 'Proximal enterocytes': '42.9', 'Paneth cells': '17.5', 'Distal enterocytes': '30.6', 'Intestinal goblet cells': '32.1', 'Exocrine glandular cells': '-0.645', 'Basal prostatic cells': '87.8', 'Prostatic glandular cells': '11.6', 'Breast glandular cells': '0.196', 'Breast myoepithelial cells': '0.372', 'Glandular and luminal cells': '1464.3', 'Secretory cells': '239.6', 'Basal keratinocytes': '563.3', 'Suprabasal keratinocytes': '566.8', 'Basal squamous epithelial cells': '378.1', 'Squamous epithelial cells': '345.1', 'Alveolar cells type 1': '-0.009', 'Alveolar cells type 2': '-0.143', 'Salivary duct cells': '291.9', 'Ductal cells': '0.789', 'Hepatocytes': '0.134', 'Cholangiocytes': '21.0', 'Proximal tubular cells': '0.197', 'Distal tubular cells': '3.1', 'Collecting duct cells': '1.9', 'Mesothelial cells': '0.018', 'Sertoli cells': '0.075', 'Granulosa cells': '40.0', 'Enteroendocrine cells': '18.1', 'Pancreatic endocrine cells': '8.5', 'Leydig cells': '0.370', 'Excitatory neurons': '0.1', 'Inhibitory neurons': '0.3', 'Cone photoreceptor cells': '27.2', 'Rod photoreceptor cells': '15.7', 'Bipolar cells': '0.7', 'Horizontal cells': '1.9', 'Astrocytes': '1.9', 'Oligodendrocyte precursor cells': '1.9', 'Oligodendrocytes': '0.3', 'Microglial cells': '8.1', 'Muller glia cells': '5.5', 'Schwann cells': '0.011', 'Spermatogonia': '0.126', 'Spermatocytes': '-0.024', 'Early spermatids': '-0.035', 'Late spermatids': '-0.353', 'Oocytes': '5.1', 'Cytotrophoblasts': '8.5', 'Syncytiotrophoblasts': '19.6', 'Extravillous trophoblasts': '115.1', 'Endothelial cells': '144.9', 'Lymphatic endothelial cells': '37.6', 'Cardiomyocytes': '0.076', 'Skeletal myocytes': '0.359', 'Smooth muscle cells': '98.4', 'Adipocytes': '63.2', 'Melanocytes': '0.090', 'Fibroblasts': '83.8', 'Peritubular cells': '0.371', 'Endometrial stromal cells': '359.1', 'Ovarian stromal cells': '34.9', 'Undifferentiated cells': '12.6', 'T-cells': '778.2', 'B-cells': '95.4', 'Plasma cells': '280.9', 'Nk-cells': '411.5', 'Granulocytes': '1749.7', 'Monocytes': '1731.0', 'Macrophages': '777.5', 'Hofbauer cells': '176.5', 'Kupffer cells': '128.4', 'Dendritic cells': '129.5', 'Langerhans cells': '0.173', 'Erythroid cells': '0.154', 'Adipocytes (Subcutaneous)': '-0.425', 'Adipocytes (Visceral)': '-0.220', 'Breast glandular cells (progenitors)': '0.080', 'Adipocytes (Breast)': '-0.482', 'Colon enterocytes': '0.003', 'Colon enteroendocrine cells': '0.117', 'Enteric glia cells': '-0.193', 'Mitotic cells (Colon)': '0.097', 'Mitotic cells (Heart)': '0.354', 'Podocytes': '0.203', 'Ascending Loop of Henle cells': '0.015', 'Intercalated cells': '0.035', 'Cholangiocyte': '0.460', 'NK-cells (Liver)': '-0.192', 'Respiratory ciliated cells': '0.038', 'Mitotic cells (Lung)': '-0.111', 'NK-cells (Lung)': '0.178', 'B-cells (Lung)': '0.275', 'Alpha cells': '0.355', 'Beta cells': '0.236', 'Prostate glandular cells': '-0.177', 'Prostate basal glandular cells': '0.085', 'Urothelial cells': '0.154', 'Keratinocyte (other)': '0.355', 'Keratinocyte (granular)': '0.073', 'Hair cortex cells': '-0.229', 'Inner root sheath cells': '-0.173', 'Outer root sheath cells': '-0.203', 'Sebaceous gland cells': '-0.246', 'Eccrine sweat gland cells': '-0.219', 'Adipocytes (Skin)': '-0.360', 'Mitotic cells (Skin)': '0.009', 'Parietal cells': '-0.352', 'Chief cells': '-0.303', 'Gastric mucous cells': '-0.072', 'Gastric enteroendocrine cells': '-0.148', 'Mitotic cells (Stomach)': '0.111', 'Parafollicular cells': '0.005', 'Thyroid glandular cells': '-0.055', 'Mitotic cells (Thyroid)': '0.346', 'Adrenal cortex cells': '0.171', 'Adrenal medulla cells': '-0.001', 'Mitotic cells (Adrenal gland)': '-0.127', 'Minor salivary glandular cells': '0.610', 'Minor salivary gland ductal cells': '0.258', 'Minor salivary gland basal cells': '0.129', 'Mitotic cells (Minor salivary gland)': '0.169', 'Adipocytes (Minor salivary gland)': '0.167', 'Somatotropes': '-0.211', 'Lactotropes': '-0.389', 'Gonadotropes': '0.036', 'Corticotropes': '-0.232', 'Thyrotropes': '-0.083', 'Undifferentiated cells (Pituitary gland)': '0.183', 'Mitotic cells (Spleen)': '-0.149', 'Platelets': '-0.130', 'Erythrocytes': '-0.171', 'Hematopoietic stem cells': '-0.172', 'B-cells (Spleen)': '0.435', 'NK-cells (Spleen)': '0.215', 'Amygdala excitatory': '0.7', 'Cerebellar inhibitory': '2.7', 'Cge interneuron': '0.4', 'Deep-layer corticothalamic and 6b': '0.4', 'Deep-layer intratelencephalic': '0.5', 'Deep-layer near-projecting': '0.1', 'Eccentric medium spiny neuron': '0.5', 'Hippocampal ca1-3': '0.5', 'Hippocampal ca4': '1.3', 'Hippocampal dentate gyrus': '0.5', 'Lamp5-lhx6 and chandelier': '0.9', 'Lower rhombic lip': '1.3', 'Mammillary body': '0.2', 'Medium spiny neuron': '0.4', 'Mge interneuron': '0.1', 'Midbrain-derived inhibitory': '0.0', 'Miscellaneous': '0.2', 'Splatter': '1.2', 'Thalamic excitatory': '2.3', 'Upper rhombic lip': '0.1', 'Upper-layer intratelencephalic': '0.6', 'Astrocyte': '3.0', 'Bergmann glia': '2.5', 'Central nervous system macrophage': '24.4', 'Choroid plexus epithelial cell': '0.7', 'Committed oligodendrocyte precursor': '1.6', 'Ependymal cell': '2.1', 'Oligodendrocyte': '0.7', 'Oligodendrocyte precursor cell': '2.0', 'Endothelial cell': '51.5', 'Pericyte': '15.8', 'Vascular associated smooth muscle cell': '12.1', 'Fibroblast': '17.8', 'Leukocyte': '94.2', 'Basophil': '92.3', 'Eosinophil': '5.6', 'Neutrophil': '3039.7', 'Classical monocyte': '535.9', 'Non-classical monocyte': '75.6', 'Intermediate monocyte': '1330.1', 'T-reg': '572.8', 'GdT-cell': '11.5', 'MAIT T-cell': '1817.4', 'Memory CD4 T-cell': '11.1', 'Naive CD4 T-cell': '1624.2', 'Memory CD8 T-cell': '10.9', 'Naive CD8 T-cell': '1289.0', 'Memory B-cell': '4.6', 'Naive B-cell': '193.4', 'Plasmacytoid DC': '146.7', 'Myeloid DC': '771.0', 'NK-cell': '630.7', 'Total PBMC': '438.1', 'Vd2 gdTCR': '1321.8', 'Memory CD4 T-cell Th1\\/Th17': '4758.2', 'Memory CD4 T-cell Th17': '2777.6', 'Memory CD4 T-cell Th2': '2696.4', 'Non-Vd2 gdTCR': '697.3', 'Memory CD4 T-cell Th1': '3101.6', 'Memory CD4 T-cell TFH': '1767.2', 'Terminal effector memory CD4 T-cell': '586.0', 'Central memory CD8 T-cell': '1346.2', 'Effector memory CD8 T-cell': '1030.8', 'Terminal effector memory CD8 T-cell': '643.9', 'Non-switched memory B-cell': '183.3', 'Plasmablast': '108.3', 'Switched memory B-cell': '133.9', 'Exhausted memory B-cell': '184.7', 'Progenitor cell': '61.7', 'Memory T-reg': '1316.7', 'Naive CD4 T-cell activated': '1454.6', 'Naive CD8 T-cell activated': '1341.5', 'Naive T-reg': '813.0'}
2EQE, 2EQF, 2EQG, 2VFJ, 3DKB, 3OJ3, 3OJ4, 3VUW, 3VUX, 3VUY, 3ZJD, 3ZJE, 3ZJF, 3ZJG, 5LRX, 5V3B, 5V3P
{'Adipose Tissue': 71.89422425249168, 'Adrenal Gland': 18.808178294573644, 'Bladder': 27.82095238095238, 'Blood': 90.27551883745964, 'Blood Vessel': 22.304372284644195, 'Brain': 2.4634945495836487, 'Breast': 38.57104575163399, 'Cervix Uteri': 22.62152631578947, 'Colon': 29.911654685494224, 'Esophagus': 23.34145743944637, 'Fallopian Tube': 47.24111111111111, 'Heart': 12.724618118466898, 'Kidney': 16.023370786516853, 'Liver': 11.73166814159292, 'Lung': 103.90608996539792, 'Muscle': 5.374799252801993, 'Nerve': 35.55016155088853, 'Ovary': 131.08455555555557, 'Pancreas': 9.580134146341464, 'Pituitary': 13.757773851590104, 'Prostate': 30.354032653061225, 'Salivary Gland': 23.303753086419754, 'Skin': 55.29272028745163, 'Small Intestine': 50.19026737967914, 'Spleen': 57.31813278008299, 'Stomach': 21.495189415041786, 'Testis': 14.136614958448757, 'Thyroid': 23.792597243491574, 'Uterus': 30.784436619718313, 'Vagina': 27.45127564102564}
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[0.94, 0.53, 0.72, 0.93, 0.52, 0.04, 0.22, 0.34, 0.11, 0.03, 0.25, 0.49, 0.28, 0.32, 0.47, 0.85, 0.12, 0.02, 0.37, 0.49, 0.03, 0.18, 0.58, 0.39, 0.04, 0.48, 0.69, 0.07, 0.23, 0.5, 0.56, 0.16, 0.94, 0.71, 0.69, 0.44, 0.1, 0.08, 0.09, 0.0, 0.45, 0.48, 0.01, 0.0, 0.42, 0.16, 0.02, 0.04, 0.04, 0.05, 0.05, 0.4, 0.1, 0.48, 0.64, 0.06, 0.28, 0.65, 0.65, 0.03, 0.3, 0.51, 0.25, 0.01, 0.24, 0.52, 0.02, 0.04, 0.12, 0.18, 0.41, 0.74, 0.05, 0.09, 0.52, 0.26, 0.0, 0.25, 0.64, 0.28, 0.51, 0.1, 0.02, 0.37, 0.16, 0.09, 0.83, 0.33, 0.11, 0.16, 0.47, 0.04, 0.05, 0.0, 0.03, 0.27, 0.14, 0.24, 0.5, 0.16, 0.07, 0.0, 0.09, 0.02, 0.0, 0.03, 0.0, 0.0, 0.03, 0.04, 0.01, 0.0, 0.03, 0.02, 0.02, 0.06, 0.05, 0.45, 0.3, 0.11, 0.15, 0.01, 0.0, 0.5, 0.06, 0.0, 0.33, 0.1, 0.0, 0.05, 0.7, 0.65, 0.27, 0.56, 0.15, 0.66, 0.43, 0.02, 0.17, 0.5, 0.05, 0.06, 0.27, 0.17, 0.19, 0.18, 0.44, 0.56, 0.14, 0.56, 0.48, 0.16, 0.69, 0.71, 0.68, 0.56, 0.44, 0.87, 0.3, 0.49, 0.36, 0.69, 0.37, 0.09, 0.41, 0.51, 0.4, 0.05, 0.61, 0.52, 0.05, 0.09, 0.62, 0.21, 0.0, 0.03, 0.35, 0.62, 0.74, 0.16, 0.87, 0.92, 0.93, 0.57, 0.67, 0.31, 0.33, 0.11, 0.3, 0.47, 0.11, 0.36, 0.16, 0.02, 0.0, 0.0, 0.0, 0.0, 0.01, 0.0, 0.0, 0.0, 0.0, 0.1, 0.0, 0.0, 0.0, 0.0, 0.01, 0.12, 0.11, 0.13, 0.29, 0.5, 0.32, 0.57, 0.24, 0.96, 0.77, 0.66, 0.48, 0.53, 0.57, 0.75, 0.45, 0.48, 0.17, 0.3, 0.08, 0.22, 0.0, 0.0, 0.0, 0.0, 0.0, 0.12, 0.36, 0.08, 0.51, 0.09, 0.89, 0.43, 0.12, 0.17, 0.35, 0.27, 0.0, 0.0, 0.0, 0.0, 0.0, 0.08, 0.22, 0.86, 0.6, 0.16, 0.03, 0.0, 0.0, 0.0, 0.0, 0.02, 0.21, 0.35, 0.32, 0.89, 0.29, 0.94, 0.46, 0.37, 0.2, 0.03, 0.02, 0.16, 0.03, 0.1, 0.13, 0.36, 0.28, 0.94, 0.52, 0.6, 0.24, 0.31, 0.57, 0.12, 0.37, 0.14, 0.0, 0.02, 0.08, 0.18, 0.49, 0.53, 0.14, 0.52, 0.86, 0.38, 0.25, 0.45, 0.55, 0.06, 0.06, 0.58, 0.37, 0.08, 0.0, 0.31, 0.25, 0.26, 0.67, 0.0, 0.56, 0.04, 0.65, 0.1, 0.37, 0.69, 0.91, 0.85, 0.36, 0.7, 0.44, 0.66, 0.03, 0.26, 0.0, 0.0, 0.4, 0.04, 0.08, 0.63, 0.37, 0.36, 0.14, 0.31, 0.74, 0.62, 0.06, 0.06, 0.01, 0.03, 0.37, 0.25, 0.0, 0.29, 0.71, 0.29, 0.0, 0.49, 0.58, 0.16, 0.19, 0.59, 0.39, 0.32, 0.47, 0.43, 0.61, 0.39, 0.56, 0.51, 0.64, 0.86, 0.78, 0.69, 0.75, 0.96, 0.82, 0.99, 0.9, 0.98, 0.9, 0.92, 0.77, 0.81, 0.79, 0.55, 0.72, 0.64, 0.51, 0.67, 0.3, 0.87, 0.52, 0.82, 0.09, 0.66, 0.35, 0.92, 0.95, 0.2, 0.85, 0.48, 0.43, 0.12, 0.08, 0.41, 0.71, 0.17, 0.54, 0.32, 0.09, 0.03, 0.37, 0.42, 0.13, 0.15, 0.42, 0.6, 0.58, 0.56, 0.58, 0.72, 0.69, 0.81, 0.78, 0.85, 0.87, 0.93, 0.94, 0.93, 0.99, 0.99, 1.0, 0.98, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 0.85, 1.0, 0.81, 1.0, 1.0, 1.0, 1.0, 1.0, 0.95, 0.99, 0.95, 0.96, 0.98, 1.0, 1.0, 1.0, 1.0, 0.71, 0.91, 0.9, 0.89, 0.99, 1.0, 0.99, 0.95, 0.91, 0.95, 0.68, 0.99, 0.9, 0.88, 0.95, 0.75, 0.69, 0.86, 0.58, 0.61, 0.41, 0.63, 0.07, 0.48, 0.32, 0.93, 0.92, 0.16, 0.9, 0.53, 0.57, 0.27, 0.31, 0.52, 0.74, 0.2, 0.68, 0.1, 0.14, 0.08, 0.59, 0.74, 0.19, 0.23, 0.44, 0.37, 0.61, 0.54, 0.65, 0.75, 0.7, 0.84, 0.75, 0.92, 0.91, 0.88, 0.97, 0.76, 0.91, 0.94, 0.45, 0.52, 0.82, 0.25, 0.35, 0.01, 0.53, 0.58, 0.38, 0.7, 0.65, 0.64, 0.26, 1.0, 0.88, 0.38, 0.72, 0.85, 0.13, 0.26, 0.06, 0.64, 0.59, 0.08, 0.45, 0.7, 0.57, 0.67, 0.6, 0.71, 0.67, 0.82, 0.81, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 0.99, 1.0, 1.0, 1.0, 1.0, 0.99, 1.0, 0.99, 0.98, 0.96, 0.98, 0.98, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 0.99, 0.99, 0.87, 0.95, 0.92, 0.9, 0.74, 0.74, 0.48, 0.82, 0.08, 0.71, 0.43, 0.94, 0.88, 0.19, 0.87, 0.56, 0.61, 0.08, 0.35, 0.84, 0.81, 0.18, 0.57, 0.19, 0.1, 0.07, 0.57, 0.62, 0.07, 0.24, 0.42, 0.37, 0.36, 0.54, 0.45, 0.65, 0.58, 0.66, 0.76, 0.69, 0.72, 0.72, 0.82, 0.78, 0.98, 0.94, 0.98, 0.91, 0.97, 0.99, 0.98, 0.97, 0.98, 0.96, 0.76, 0.77, 0.43, 0.74, 0.08, 0.55, 0.2, 0.96, 0.96, 0.18, 0.91, 0.5, 0.65, 0.16, 0.34, 0.75, 0.86, 0.36, 0.41, 0.1, 0.2, 0.14, 0.54, 0.64, 0.1, 0.22, 0.54, 0.46, 0.17, 0.14, 0.5, 0.57, 0.36, 0.64, 0.59, 0.44, 0.52, 0.49, 0.63, 0.49, 0.51, 0.53, 0.64, 0.57, 0.69, 0.68, 0.62, 0.83, 0.92, 0.9, 0.99, 0.93, 0.99, 0.95, 1.0, 0.93, 0.96, 0.97, 0.73, 0.89, 0.81, 0.38, 0.77, 0.07, 0.63, 0.45, 0.92, 0.8, 0.2, 0.91, 0.32, 0.61, 0.09, 0.94, 0.46, 0.78, 0.81, 0.41, 0.77, 0.39, 0.09, 0.6, 0.74, 0.1, 0.44, 0.73, 0.61, 0.94, 0.99, 1.0, 1.0, 0.99, 1.0, 1.0, 1.0, 1.0, 1.0, 0.96, 0.99, 0.99, 0.93, 0.96, 0.95, 0.71, 0.85, 0.88, 0.6, 0.69, 0.62, 0.09, 0.64, 0.22, 0.94, 0.92, 0.11, 0.67, 0.55, 0.58, 0.25, 0.33, 0.83, 0.88, 0.1, 0.57, 0.17, 0.2, 0.06, 0.59, 0.65, 0.22, 0.26, 0.36, 0.59, 0.44, 0.69, 0.71, 0.77, 0.72]
ZnF_A20
component of a ubiquitin-editing protein complex, comprising also RNF11, ITCH and TAX1BP1
null
null
IKBKG, ITCH, YWHAH, TRAF6, RIPK1, TRAF2, TNIP1, TAX1BP1, RNF11, YWHAZ
UBE2N, UBE2D3, RIPK1
11, 48, 63
null
UBE2N, UBE2D3
Homodimer
null
74.507911
0.508165
74.507911
0.508165
818
P21580
Q13546
15258597, TNAP3_HUMAN, BioGrid E3Net
UbiNet, UbiBrowser, 31181401
TNFAIP3
MAEQVLPQALYLSNMRKAVKIRERTPEDIFKPTNGIIHHFKTMHRYTLEMFRTCQFCPQFREIIHKALIDRNIQATLESQKKLNWCREVRKLVALKTNGDGNCLMHATSQYMWGVQDTDLVLRKALFSTLKETDTRNFKFRWQLESLKSQEFVETGLCYDTRNWNDEWDNLIKMASTDTPMARSGLQYNSLEEIHIFVLCNILRRPIIVISDKMLRSLESGSNFAPLKVGGIYLPLHWPAQECYRYPIVLGYDSHHFVPLVTLKDSGPEIRAVPLVNRDRGRFEDLKVHFLTDPENEMKEKLLKEYLMVIEIPVQGWDHGTTHLINAAKLDEANLPKEINLVDDYFELVQHEYKKWQENSEQGRREGHAQNPMEPSVPQLSLMDVKCETPNCPFFMSVNTQPLCHECSERRQKNQNKLPKLNSKPGPEGLPGMALGASRGEAYEPLAWNPEESTGGPHSAPPTAPSPFLFSETTAMKCRSPGCPFTLNVQHNGFCERCHNARQLHASHAPDHTRHLDPGKCQACLQDVTRTFNGICSTCFKRTTAEASSSLSTSLPPSCHQRSKSDPSRLVRSPSPHSCHRAGNDAPAGCLSQAARTPGDRTGTSKCRKAGCVYFGTPENKGFCTLCFIEYRENKHFAAASGKVSPTASRFQNTIPCLGRECGTLGSTMFEGYCQKCFIEAQNQRFHEAKRTEEQLRSSQRRDVPRTTQSTSRPKCARASCKNILACRSEELCMECQHPNQRMGPGAHRGEPAPEDPPKQRCRAPACDHFGNAKCNGYCNECFQFKQMYG
Homo sapiens
Cytoplasm, Nucleus, Lysosome, Cytoplasm
Tissue enhanced (bone marrow, urinary bladder)
{'Ciliated cells': '222.0', 'Basal respiratory cells': '102.4', 'Club cells': '102.0', 'Ionocytes': '151.3', 'Mucus glandular cells': '266.5', 'Serous glandular cells': '115.3', 'Gastric mucus-secreting cells': '78.4', 'Proximal enterocytes': '42.9', 'Paneth cells': '17.5', 'Distal enterocytes': '30.6', 'Intestinal goblet cells': '32.1', 'Exocrine glandular cells': '-0.645', 'Basal prostatic cells': '87.8', 'Prostatic glandular cells': '11.6', 'Breast glandular cells': '0.196', 'Breast myoepithelial cells': '0.372', 'Glandular and luminal cells': '1464.3', 'Secretory cells': '239.6', 'Basal keratinocytes': '563.3', 'Suprabasal keratinocytes': '566.8', 'Basal squamous epithelial cells': '378.1', 'Squamous epithelial cells': '345.1', 'Alveolar cells type 1': '-0.009', 'Alveolar cells type 2': '-0.143', 'Salivary duct cells': '291.9', 'Ductal cells': '0.789', 'Hepatocytes': '0.134', 'Cholangiocytes': '21.0', 'Proximal tubular cells': '0.197', 'Distal tubular cells': '3.1', 'Collecting duct cells': '1.9', 'Mesothelial cells': '0.018', 'Sertoli cells': '0.075', 'Granulosa cells': '40.0', 'Enteroendocrine cells': '18.1', 'Pancreatic endocrine cells': '8.5', 'Leydig cells': '0.370', 'Excitatory neurons': '0.1', 'Inhibitory neurons': '0.3', 'Cone photoreceptor cells': '27.2', 'Rod photoreceptor cells': '15.7', 'Bipolar cells': '0.7', 'Horizontal cells': '1.9', 'Astrocytes': '1.9', 'Oligodendrocyte precursor cells': '1.9', 'Oligodendrocytes': '0.3', 'Microglial cells': '8.1', 'Muller glia cells': '5.5', 'Schwann cells': '0.011', 'Spermatogonia': '0.126', 'Spermatocytes': '-0.024', 'Early spermatids': '-0.035', 'Late spermatids': '-0.353', 'Oocytes': '5.1', 'Cytotrophoblasts': '8.5', 'Syncytiotrophoblasts': '19.6', 'Extravillous trophoblasts': '115.1', 'Endothelial cells': '144.9', 'Lymphatic endothelial cells': '37.6', 'Cardiomyocytes': '0.076', 'Skeletal myocytes': '0.359', 'Smooth muscle cells': '98.4', 'Adipocytes': '63.2', 'Melanocytes': '0.090', 'Fibroblasts': '83.8', 'Peritubular cells': '0.371', 'Endometrial stromal cells': '359.1', 'Ovarian stromal cells': '34.9', 'Undifferentiated cells': '12.6', 'T-cells': '778.2', 'B-cells': '95.4', 'Plasma cells': '280.9', 'Nk-cells': '411.5', 'Granulocytes': '1749.7', 'Monocytes': '1731.0', 'Macrophages': '777.5', 'Hofbauer cells': '176.5', 'Kupffer cells': '128.4', 'Dendritic cells': '129.5', 'Langerhans cells': '0.173', 'Erythroid cells': '0.154', 'Adipocytes (Subcutaneous)': '-0.425', 'Adipocytes (Visceral)': '-0.220', 'Breast glandular cells (progenitors)': '0.080', 'Adipocytes (Breast)': '-0.482', 'Colon enterocytes': '0.003', 'Colon enteroendocrine cells': '0.117', 'Enteric glia cells': '-0.193', 'Mitotic cells (Colon)': '0.097', 'Mitotic cells (Heart)': '0.354', 'Podocytes': '0.203', 'Ascending Loop of Henle cells': '0.015', 'Intercalated cells': '0.035', 'Cholangiocyte': '0.460', 'NK-cells (Liver)': '-0.192', 'Respiratory ciliated cells': '0.038', 'Mitotic cells (Lung)': '-0.111', 'NK-cells (Lung)': '0.178', 'B-cells (Lung)': '0.275', 'Alpha cells': '0.355', 'Beta cells': '0.236', 'Prostate glandular cells': '-0.177', 'Prostate basal glandular cells': '0.085', 'Urothelial cells': '0.154', 'Keratinocyte (other)': '0.355', 'Keratinocyte (granular)': '0.073', 'Hair cortex cells': '-0.229', 'Inner root sheath cells': '-0.173', 'Outer root sheath cells': '-0.203', 'Sebaceous gland cells': '-0.246', 'Eccrine sweat gland cells': '-0.219', 'Adipocytes (Skin)': '-0.360', 'Mitotic cells (Skin)': '0.009', 'Parietal cells': '-0.352', 'Chief cells': '-0.303', 'Gastric mucous cells': '-0.072', 'Gastric enteroendocrine cells': '-0.148', 'Mitotic cells (Stomach)': '0.111', 'Parafollicular cells': '0.005', 'Thyroid glandular cells': '-0.055', 'Mitotic cells (Thyroid)': '0.346', 'Adrenal cortex cells': '0.171', 'Adrenal medulla cells': '-0.001', 'Mitotic cells (Adrenal gland)': '-0.127', 'Minor salivary glandular cells': '0.610', 'Minor salivary gland ductal cells': '0.258', 'Minor salivary gland basal cells': '0.129', 'Mitotic cells (Minor salivary gland)': '0.169', 'Adipocytes (Minor salivary gland)': '0.167', 'Somatotropes': '-0.211', 'Lactotropes': '-0.389', 'Gonadotropes': '0.036', 'Corticotropes': '-0.232', 'Thyrotropes': '-0.083', 'Undifferentiated cells (Pituitary gland)': '0.183', 'Mitotic cells (Spleen)': '-0.149', 'Platelets': '-0.130', 'Erythrocytes': '-0.171', 'Hematopoietic stem cells': '-0.172', 'B-cells (Spleen)': '0.435', 'NK-cells (Spleen)': '0.215', 'Amygdala excitatory': '0.7', 'Cerebellar inhibitory': '2.7', 'Cge interneuron': '0.4', 'Deep-layer corticothalamic and 6b': '0.4', 'Deep-layer intratelencephalic': '0.5', 'Deep-layer near-projecting': '0.1', 'Eccentric medium spiny neuron': '0.5', 'Hippocampal ca1-3': '0.5', 'Hippocampal ca4': '1.3', 'Hippocampal dentate gyrus': '0.5', 'Lamp5-lhx6 and chandelier': '0.9', 'Lower rhombic lip': '1.3', 'Mammillary body': '0.2', 'Medium spiny neuron': '0.4', 'Mge interneuron': '0.1', 'Midbrain-derived inhibitory': '0.0', 'Miscellaneous': '0.2', 'Splatter': '1.2', 'Thalamic excitatory': '2.3', 'Upper rhombic lip': '0.1', 'Upper-layer intratelencephalic': '0.6', 'Astrocyte': '3.0', 'Bergmann glia': '2.5', 'Central nervous system macrophage': '24.4', 'Choroid plexus epithelial cell': '0.7', 'Committed oligodendrocyte precursor': '1.6', 'Ependymal cell': '2.1', 'Oligodendrocyte': '0.7', 'Oligodendrocyte precursor cell': '2.0', 'Endothelial cell': '51.5', 'Pericyte': '15.8', 'Vascular associated smooth muscle cell': '12.1', 'Fibroblast': '17.8', 'Leukocyte': '94.2', 'Basophil': '92.3', 'Eosinophil': '5.6', 'Neutrophil': '3039.7', 'Classical monocyte': '535.9', 'Non-classical monocyte': '75.6', 'Intermediate monocyte': '1330.1', 'T-reg': '572.8', 'GdT-cell': '11.5', 'MAIT T-cell': '1817.4', 'Memory CD4 T-cell': '11.1', 'Naive CD4 T-cell': '1624.2', 'Memory CD8 T-cell': '10.9', 'Naive CD8 T-cell': '1289.0', 'Memory B-cell': '4.6', 'Naive B-cell': '193.4', 'Plasmacytoid DC': '146.7', 'Myeloid DC': '771.0', 'NK-cell': '630.7', 'Total PBMC': '438.1', 'Vd2 gdTCR': '1321.8', 'Memory CD4 T-cell Th1\\/Th17': '4758.2', 'Memory CD4 T-cell Th17': '2777.6', 'Memory CD4 T-cell Th2': '2696.4', 'Non-Vd2 gdTCR': '697.3', 'Memory CD4 T-cell Th1': '3101.6', 'Memory CD4 T-cell TFH': '1767.2', 'Terminal effector memory CD4 T-cell': '586.0', 'Central memory CD8 T-cell': '1346.2', 'Effector memory CD8 T-cell': '1030.8', 'Terminal effector memory CD8 T-cell': '643.9', 'Non-switched memory B-cell': '183.3', 'Plasmablast': '108.3', 'Switched memory B-cell': '133.9', 'Exhausted memory B-cell': '184.7', 'Progenitor cell': '61.7', 'Memory T-reg': '1316.7', 'Naive CD4 T-cell activated': '1454.6', 'Naive CD8 T-cell activated': '1341.5', 'Naive T-reg': '813.0'}
2EQE, 2EQF, 2EQG, 2VFJ, 3DKB, 3OJ3, 3OJ4, 3VUW, 3VUX, 3VUY, 3ZJD, 3ZJE, 3ZJF, 3ZJG, 5LRX, 5V3B, 5V3P
{'Adipose Tissue': 71.89422425249168, 'Adrenal Gland': 18.808178294573644, 'Bladder': 27.82095238095238, 'Blood': 90.27551883745964, 'Blood Vessel': 22.304372284644195, 'Brain': 2.4634945495836487, 'Breast': 38.57104575163399, 'Cervix Uteri': 22.62152631578947, 'Colon': 29.911654685494224, 'Esophagus': 23.34145743944637, 'Fallopian Tube': 47.24111111111111, 'Heart': 12.724618118466898, 'Kidney': 16.023370786516853, 'Liver': 11.73166814159292, 'Lung': 103.90608996539792, 'Muscle': 5.374799252801993, 'Nerve': 35.55016155088853, 'Ovary': 131.08455555555557, 'Pancreas': 9.580134146341464, 'Pituitary': 13.757773851590104, 'Prostate': 30.354032653061225, 'Salivary Gland': 23.303753086419754, 'Skin': 55.29272028745163, 'Small Intestine': 50.19026737967914, 'Spleen': 57.31813278008299, 'Stomach': 21.495189415041786, 'Testis': 14.136614958448757, 'Thyroid': 23.792597243491574, 'Uterus': 30.784436619718313, 'Vagina': 27.45127564102564}
RIPK1
MQPDMSLNVIKMKSSDFLESAELDSGGFGKVSLCFHRTQGLMIMKTVYKGPNCIEHNEALLEEAKMMNRLRHSRVVKLLGVIIEEGKYSLVMEYMEKGNLMHVLKAEMSTPLSVKGRIILEIIEGMCYLHGKGVIHKDLKPENILVDNDFHIKIADLGLASFKMWSKLNNEEHNELREVDGTAKKNGGTLYYMAPEHLNDVNAKPTEKSDVYSFAVVLWAIFANKEPYENAICEQQLIMCIKSGNRPDVDDITEYCPREIISLMKLCWEANPEARPTFPGIEEKFRPFYLSQLEESVEEDVKSLKKEYSNENAVVKRMQSLQLDCVAVPSSRSNSATEQPGSLHSSQGLGMGPVEESWFAPSLEHPQEENEPSLQSKLQDEANYHLYGSRMDRQTKQQPRQNVAYNREEERRRRVSHDPFAQQRPYENFQNTEGKGTAYSSAASHGNAVHQPSGLTSQPQVLYQNNGLYSSHGFGTRPLDPGTAGPRVWYRPIPSHMPSLHNIPVPETNYLGNTPTMPFSSLPPTDESIKYTIYNSTGIQIGAYNYMEIGGTSSSLLDSTNTNFKEEPAAKYQAIFDNTTSLTDKHLDPIRENLGKHWKNCARKLGFTQSQIDEIDHDYERDGLKEKVYQMLQKWVMREGIKGATVGKLAQALHQCSRIDLLSSLIYVSQN
Homo sapiens
Cytoplasm, Cell membrane
Low tissue specificity
{'Ciliated cells': '15.7', 'Basal respiratory cells': '10.3', 'Club cells': '17.3', 'Ionocytes': '18.4', 'Mucus glandular cells': '27.3', 'Serous glandular cells': '21.2', 'Gastric mucus-secreting cells': '42.4', 'Proximal enterocytes': '28.4', 'Paneth cells': '17.2', 'Distal enterocytes': '27.0', 'Intestinal goblet cells': '24.0', 'Exocrine glandular cells': '-0.692', 'Basal prostatic cells': '24.2', 'Prostatic glandular cells': '18.7', 'Breast glandular cells': '0.125', 'Breast myoepithelial cells': '-0.063', 'Glandular and luminal cells': '19.3', 'Secretory cells': '23.0', 'Basal keratinocytes': '18.6', 'Suprabasal keratinocytes': '19.4', 'Basal squamous epithelial cells': '23.3', 'Squamous epithelial cells': '32.1', 'Alveolar cells type 1': '0.124', 'Alveolar cells type 2': '0.272', 'Salivary duct cells': '31.2', 'Ductal cells': '0.588', 'Hepatocytes': '0.304', 'Cholangiocytes': '15.3', 'Proximal tubular cells': '0.217', 'Distal tubular cells': '6.1', 'Collecting duct cells': '15.6', 'Mesothelial cells': '-0.059', 'Sertoli cells': '0.537', 'Granulosa cells': '17.4', 'Enteroendocrine cells': '14.5', 'Pancreatic endocrine cells': '11.9', 'Leydig cells': '0.668', 'Excitatory neurons': '22.3', 'Inhibitory neurons': '25.6', 'Cone photoreceptor cells': '10.2', 'Rod photoreceptor cells': '35.7', 'Bipolar cells': '7.3', 'Horizontal cells': '7.6', 'Astrocytes': '16.4', 'Oligodendrocyte precursor cells': '13.7', 'Oligodendrocytes': '15.1', 'Microglial cells': '10.7', 'Muller glia cells': '11.1', 'Schwann cells': '0.170', 'Spermatogonia': '0.404', 'Spermatocytes': '0.061', 'Early spermatids': '-0.525', 'Late spermatids': '-0.695', 'Oocytes': '2.2', 'Cytotrophoblasts': '10.6', 'Syncytiotrophoblasts': '14.6', 'Extravillous trophoblasts': '9.3', 'Endothelial cells': '25.7', 'Lymphatic endothelial cells': '28.0', 'Cardiomyocytes': '0.368', 'Skeletal myocytes': '-0.331', 'Smooth muscle cells': '26.3', 'Adipocytes': '39.9', 'Melanocytes': '0.001', 'Fibroblasts': '22.3', 'Peritubular cells': '0.544', 'Endometrial stromal cells': '19.4', 'Ovarian stromal cells': '6.2', 'Undifferentiated cells': '11.9', 'T-cells': '29.5', 'B-cells': '19.4', 'Plasma cells': '26.1', 'Nk-cells': '32.1', 'Granulocytes': '23.0', 'Monocytes': '39.9', 'Macrophages': '28.5', 'Hofbauer cells': '14.8', 'Kupffer cells': '10.3', 'Dendritic cells': '37.8', 'Langerhans cells': '0.240', 'Erythroid cells': '-0.128', 'Adipocytes (Subcutaneous)': '0.241', 'Adipocytes (Visceral)': '0.313', 'Breast glandular cells (progenitors)': '0.025', 'Adipocytes (Breast)': '0.172', 'Colon enterocytes': '0.036', 'Colon enteroendocrine cells': '0.103', 'Enteric glia cells': '-0.286', 'Mitotic cells (Colon)': '0.070', 'Mitotic cells (Heart)': '0.464', 'Podocytes': '-0.198', 'Ascending Loop of Henle cells': '0.303', 'Intercalated cells': '-0.119', 'Cholangiocyte': '0.211', 'NK-cells (Liver)': '-0.222', 'Respiratory ciliated cells': '-0.078', 'Mitotic cells (Lung)': '0.046', 'NK-cells (Lung)': '-0.097', 'B-cells (Lung)': '-0.216', 'Alpha cells': '0.304', 'Beta cells': '0.195', 'Prostate glandular cells': '-0.100', 'Prostate basal glandular cells': '0.318', 'Urothelial cells': '0.252', 'Keratinocyte (other)': '0.244', 'Keratinocyte (granular)': '0.292', 'Hair cortex cells': '-0.248', 'Inner root sheath cells': '-0.269', 'Outer root sheath cells': '-0.289', 'Sebaceous gland cells': '0.026', 'Eccrine sweat gland cells': '-0.246', 'Adipocytes (Skin)': '-0.149', 'Mitotic cells (Skin)': '-0.226', 'Parietal cells': '-0.446', 'Chief cells': '-0.419', 'Gastric mucous cells': '-0.130', 'Gastric enteroendocrine cells': '-0.296', 'Mitotic cells (Stomach)': '0.183', 'Parafollicular cells': '-0.018', 'Thyroid glandular cells': '0.350', 'Mitotic cells (Thyroid)': '-0.021', 'Adrenal cortex cells': '0.496', 'Adrenal medulla cells': '0.137', 'Mitotic cells (Adrenal gland)': '0.311', 'Minor salivary glandular cells': '0.542', 'Minor salivary gland ductal cells': '0.199', 'Minor salivary gland basal cells': '0.307', 'Mitotic cells (Minor salivary gland)': '0.248', 'Adipocytes (Minor salivary gland)': '0.156', 'Somatotropes': '-0.031', 'Lactotropes': '-0.046', 'Gonadotropes': '0.007', 'Corticotropes': '-0.042', 'Thyrotropes': '-0.011', 'Undifferentiated cells (Pituitary gland)': '0.172', 'Mitotic cells (Spleen)': '-0.283', 'Platelets': '0.062', 'Erythrocytes': '-0.095', 'Hematopoietic stem cells': '-0.185', 'B-cells (Spleen)': '0.239', 'NK-cells (Spleen)': '0.287', 'Amygdala excitatory': '40.6', 'Cerebellar inhibitory': '37.2', 'Cge interneuron': '39.6', 'Deep-layer corticothalamic and 6b': '29.9', 'Deep-layer intratelencephalic': '44.3', 'Deep-layer near-projecting': '39.5', 'Eccentric medium spiny neuron': '33.7', 'Hippocampal ca1-3': '39.5', 'Hippocampal ca4': '44.1', 'Hippocampal dentate gyrus': '32.0', 'Lamp5-lhx6 and chandelier': '44.6', 'Lower rhombic lip': '49.0', 'Mammillary body': '59.1', 'Medium spiny neuron': '27.3', 'Mge interneuron': '50.9', 'Midbrain-derived inhibitory': '25.7', 'Miscellaneous': '39.4', 'Splatter': '41.5', 'Thalamic excitatory': '50.4', 'Upper rhombic lip': '44.6', 'Upper-layer intratelencephalic': '44.8', 'Astrocyte': '34.6', 'Bergmann glia': '29.5', 'Central nervous system macrophage': '71.8', 'Choroid plexus epithelial cell': '25.9', 'Committed oligodendrocyte precursor': '25.5', 'Ependymal cell': '26.1', 'Oligodendrocyte': '26.9', 'Oligodendrocyte precursor cell': '33.5', 'Endothelial cell': '62.0', 'Pericyte': '67.4', 'Vascular associated smooth muscle cell': '50.8', 'Fibroblast': '55.6', 'Leukocyte': '71.6', 'Basophil': '1.4', 'Eosinophil': '0.9', 'Neutrophil': '5.1', 'Classical monocyte': '41.5', 'Non-classical monocyte': '58.9', 'Intermediate monocyte': '2.8', 'T-reg': '0.6', 'GdT-cell': '0.6', 'MAIT T-cell': '1.4', 'Memory CD4 T-cell': '0.9', 'Naive CD4 T-cell': '83.1', 'Memory CD8 T-cell': '1.7', 'Naive CD8 T-cell': '68.3', 'Memory B-cell': '0.3', 'Naive B-cell': '45.4', 'Plasmacytoid DC': '3.7', 'Myeloid DC': '1.7', 'NK-cell': '122.3', 'Total PBMC': '2.1', 'Vd2 gdTCR': '2.0', 'Memory CD4 T-cell Th1\\/Th17': '92.1', 'Memory CD4 T-cell Th17': '91.1', 'Memory CD4 T-cell Th2': '89.7', 'Non-Vd2 gdTCR': '1.7', 'Memory CD4 T-cell Th1': '94.0', 'Memory CD4 T-cell TFH': '89.5', 'Terminal effector memory CD4 T-cell': '1.6', 'Central memory CD8 T-cell': '3.7', 'Effector memory CD8 T-cell': '4.0', 'Terminal effector memory CD8 T-cell': '4.7', 'Non-switched memory B-cell': '0.9', 'Plasmablast': '1.7', 'Switched memory B-cell': '2.1', 'Exhausted memory B-cell': '2.9', 'Progenitor cell': '2.7', 'Memory T-reg': '90.4', 'Naive CD4 T-cell activated': '72.4', 'Naive CD8 T-cell activated': '78.4', 'Naive T-reg': '78.7'}
4ITH, 4ITI, 4ITJ, 4NEU, 5HX6, 5TX5, 5V7Z, 6AC5, 6C3E, 6C4D, 6HHO, 6NW2, 6NYH, 6OCQ, 6R5F, 6RLN, 7CJB, 7FCZ, 7FD0, 7XMK, 7YDX, 8I2N
{'Adipose Tissue': 34.59241694352159, 'Adrenal Gland': 18.182705426356588, 'Bladder': 33.005714285714284, 'Blood': 15.52713024757804, 'Blood Vessel': 30.15394531835206, 'Brain': 9.893503103709312, 'Breast': 32.56450980392157, 'Cervix Uteri': 31.43421052631579, 'Colon': 29.40317586649551, 'Esophagus': 29.210665051903113, 'Fallopian Tube': 31.51777777777778, 'Heart': 8.529487804878048, 'Kidney': 16.126247191011235, 'Liver': 17.36390707964602, 'Lung': 31.123837370242217, 'Muscle': 10.388682440846823, 'Nerve': 32.92360258481421, 'Ovary': 20.070983333333334, 'Pancreas': 12.905893292682926, 'Pituitary': 25.843180212014133, 'Prostate': 29.563624489795917, 'Salivary Gland': 27.742037037037036, 'Skin': 36.60169707020454, 'Small Intestine': 34.32989304812834, 'Spleen': 36.08161825726141, 'Stomach': 24.21554317548746, 'Testis': 13.804903047091411, 'Thyroid': 35.194134762634, 'Uterus': 35.34077464788733, 'Vagina': 29.734807692307697}
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[0.98, 0.99, 0.84, 0.9, 0.78, 0.47, 0.39, 0.71, 0.63, 0.08, 0.5, 0.1, 0.57, 0.49, 0.57, 0.31, 0.13, 0.46, 0.31, 0.72, 0.24, 0.64, 0.5, 0.61, 0.69, 0.34, 0.52, 0.36, 0.15, 0.42, 0.23, 0.14, 0.0, 0.01, 0.06, 0.11, 0.61, 0.89, 0.61, 0.23, 0.19, 0.0, 0.11, 0.16, 0.03, 0.24, 0.0, 0.06, 0.67, 0.38, 0.73, 0.53, 0.22, 0.66, 0.95, 0.26, 0.24, 0.62, 0.39, 0.0, 0.08, 0.5, 0.16, 0.0, 0.17, 0.53, 0.08, 0.18, 0.69, 0.09, 0.64, 0.32, 0.67, 0.18, 0.01, 0.1, 0.39, 0.07, 0.24, 0.01, 0.0, 0.03, 0.13, 0.31, 0.8, 0.02, 0.5, 0.0, 0.04, 0.03, 0.0, 0.14, 0.23, 0.17, 0.07, 0.39, 0.09, 0.32, 0.31, 0.0, 0.05, 0.61, 0.03, 0.04, 0.51, 0.3, 0.98, 0.26, 0.75, 0.08, 0.27, 0.38, 0.02, 0.0, 0.06, 0.0, 0.08, 0.03, 0.01, 0.09, 0.03, 0.01, 0.0, 0.25, 0.0, 0.0, 0.17, 0.2, 0.01, 0.11, 0.76, 0.62, 0.68, 0.14, 0.21, 0.0, 0.43, 0.19, 0.0, 0.04, 0.0, 0.36, 0.04, 0.0, 0.21, 0.01, 0.21, 0.47, 0.45, 0.01, 0.28, 0.01, 0.18, 0.0, 0.08, 0.2, 0.07, 0.08, 0.11, 0.22, 0.4, 0.02, 0.8, 0.2, 0.0, 0.18, 0.44, 0.01, 0.06, 0.5, 0.35, 0.19, 0.12, 0.53, 0.5, 0.44, 0.44, 0.83, 0.84, 0.52, 0.77, 0.6, 0.84, 0.53, 0.9, 0.45, 0.12, 0.32, 0.28, 0.16, 0.2, 0.03, 0.3, 0.02, 0.05, 0.23, 0.24, 0.14, 0.58, 0.49, 0.95, 0.77, 0.25, 0.83, 0.38, 0.41, 0.39, 0.15, 0.06, 0.0, 0.01, 0.0, 0.06, 0.0, 0.0, 0.0, 0.01, 0.01, 0.02, 0.0, 0.0, 0.07, 0.18, 0.29, 0.28, 0.33, 0.01, 0.14, 0.6, 0.93, 0.38, 0.79, 0.45, 0.42, 0.69, 0.4, 0.06, 0.28, 0.69, 0.34, 0.02, 0.39, 0.74, 0.54, 0.47, 0.22, 0.05, 0.5, 0.17, 0.76, 0.45, 0.01, 0.51, 0.98, 0.73, 0.08, 0.2, 0.85, 0.57, 0.0, 0.12, 0.6, 0.07, 0.0, 0.45, 0.32, 0.0, 0.06, 0.45, 0.57, 0.56, 0.24, 0.76, 0.46, 0.03, 0.16, 0.49, 0.0, 0.52, 0.21, 0.0, 0.18, 0.77, 0.58, 0.03, 0.35, 0.56, 0.16, 0.07, 0.51, 0.77, 0.79, 0.06, 0.47, 0.94, 0.38, 0.07, 0.72, 0.74, 0.25, 0.02, 0.64, 0.46, 0.04, 0.34, 0.72, 0.68, 0.15, 0.6, 0.65, 0.66, 0.37, 0.61, 0.43, 0.13, 0.47, 0.65, 0.0, 0.41, 0.68, 0.38, 0.59, 0.75, 0.81, 0.66, 0.81, 0.84, 0.79, 0.82, 0.88, 0.72, 0.92, 0.8, 0.93, 0.99, 0.75, 0.84, 0.84, 0.82, 0.9, 0.78, 0.71, 0.93, 0.84, 0.84, 0.94, 0.86, 0.95, 0.8, 0.92, 0.9, 0.82, 0.95, 0.74, 0.64, 0.78, 0.6, 0.86, 0.79, 0.62, 0.84, 0.8, 0.95, 0.87, 0.95, 0.99, 0.74, 0.94, 0.75, 0.88, 0.88, 0.57, 0.57, 0.69, 0.75, 0.42, 0.52, 0.57, 0.58, 0.39, 0.42, 0.46, 0.22, 0.51, 0.79, 0.88, 0.61, 0.6, 0.33, 0.62, 0.86, 0.51, 0.9, 0.95, 0.92, 0.92, 0.96, 0.78, 0.88, 0.71, 0.84, 0.67, 0.62, 0.67, 0.69, 0.56, 0.73, 0.53, 0.35, 0.49, 0.64, 0.67, 0.72, 0.73, 0.85, 0.67, 0.94, 0.59, 0.91, 0.87, 0.67, 0.88, 0.92, 0.96, 0.85, 0.92, 0.84, 0.84, 0.9, 0.89, 0.94, 0.9, 0.98, 0.95, 0.97, 1.0, 0.98, 0.97, 0.98, 0.9, 0.96, 0.9, 0.87, 0.97, 0.94, 0.94, 0.96, 0.9, 0.86, 0.92, 0.89, 0.97, 0.92, 0.91, 0.94, 0.97, 0.92, 0.97, 0.88, 0.94, 0.76, 0.96, 0.89, 0.98, 0.97, 0.94, 0.7, 0.94, 0.93, 0.81, 0.91, 0.82, 0.83, 0.91, 0.91, 0.95, 0.94, 0.94, 0.93, 0.95, 0.98, 0.92, 0.98, 1.0, 0.81, 0.92, 0.93, 0.79, 0.96, 0.88, 0.93, 0.89, 0.89, 0.91, 0.83, 0.91, 0.95, 0.79, 0.9, 0.89, 0.89, 0.94, 0.87, 0.89, 0.89, 0.83, 0.85, 0.87, 0.81, 0.93, 0.99, 0.68, 0.96, 0.8, 0.87, 0.86, 0.88, 0.86, 0.93, 0.76, 0.96, 0.87, 0.87, 0.98, 0.74, 0.97, 0.78, 0.84, 0.68, 0.91, 0.76, 0.66, 0.59, 0.81, 0.97, 0.57, 0.96, 0.81, 0.56, 0.99, 0.52, 0.53, 0.99, 0.97, 0.7, 0.9, 0.56, 0.89, 0.86, 0.71, 0.85, 0.78, 0.86, 0.71, 0.91, 0.9, 0.91, 0.98, 0.79, 0.85, 0.91, 0.59, 0.82, 0.82, 0.8, 0.91, 0.46, 0.66, 0.41, 0.62, 0.71, 0.06, 0.55, 0.76, 0.14, 0.25, 0.69, 0.24, 0.77, 0.51, 0.48, 0.17, 0.47, 0.55, 0.73, 0.09, 0.06, 0.44, 0.25, 0.01, 0.15, 0.66, 0.56, 0.0, 0.25, 0.83, 0.45, 0.02, 0.36, 0.48, 0.0, 0.0, 0.47, 0.54, 0.08, 0.54, 0.09, 0.56, 0.49, 0.69, 0.33, 0.0, 0.47, 0.41, 0.01, 0.25, 0.78, 0.68, 0.24, 0.69, 0.99, 0.6, 0.34, 0.39, 0.55, 0.32, 0.08, 0.0, 0.38, 0.14, 0.0, 0.0, 0.38, 0.32, 0.01, 0.33, 0.73, 0.48, 0.39, 0.33, 0.77, 0.91, 0.18, 0.01, 0.12, 0.01, 0.02, 0.42, 0.0, 0.0, 0.48, 0.03, 0.0, 0.31, 0.51, 0.13, 0.73, 0.13, 0.43, 0.57, 0.04, 0.0, 0.44, 0.35, 0.02, 0.19, 0.67, 0.24, 0.36, 0.81, 0.67]
ZnF_A20
component of a ubiquitin-editing protein complex, comprising also RNF11, ITCH and TAX1BP1
null
null
IKBKG, ITCH, YWHAH, TRAF6, RIPK1, TRAF2, TNIP1, TAX1BP1, RNF11, YWHAZ
UBE2N, UBE2D3, RIPK1
11, 48, 63
null
UBE2N, UBE2D3
Homodimer
null
74.507911
0.508165
69.18544
0.5093
1,080
P21580
Q9H4P4
34023381
UbiBrowser
TNFAIP3
MAEQVLPQALYLSNMRKAVKIRERTPEDIFKPTNGIIHHFKTMHRYTLEMFRTCQFCPQFREIIHKALIDRNIQATLESQKKLNWCREVRKLVALKTNGDGNCLMHATSQYMWGVQDTDLVLRKALFSTLKETDTRNFKFRWQLESLKSQEFVETGLCYDTRNWNDEWDNLIKMASTDTPMARSGLQYNSLEEIHIFVLCNILRRPIIVISDKMLRSLESGSNFAPLKVGGIYLPLHWPAQECYRYPIVLGYDSHHFVPLVTLKDSGPEIRAVPLVNRDRGRFEDLKVHFLTDPENEMKEKLLKEYLMVIEIPVQGWDHGTTHLINAAKLDEANLPKEINLVDDYFELVQHEYKKWQENSEQGRREGHAQNPMEPSVPQLSLMDVKCETPNCPFFMSVNTQPLCHECSERRQKNQNKLPKLNSKPGPEGLPGMALGASRGEAYEPLAWNPEESTGGPHSAPPTAPSPFLFSETTAMKCRSPGCPFTLNVQHNGFCERCHNARQLHASHAPDHTRHLDPGKCQACLQDVTRTFNGICSTCFKRTTAEASSSLSTSLPPSCHQRSKSDPSRLVRSPSPHSCHRAGNDAPAGCLSQAARTPGDRTGTSKCRKAGCVYFGTPENKGFCTLCFIEYRENKHFAAASGKVSPTASRFQNTIPCLGRECGTLGSTMFEGYCQKCFIEAQNQRFHEAKRTEEQLRSSQRRDVPRTTQSTSRPKCARASCKNILACRSEELCMECQHPNQRMGPGAHRGEPAPEDPPKQRCRAPACDHFGNAKCNGYCNECFQFKQMYG
Homo sapiens
Cytoplasm, Nucleus, Lysosome, Cytoplasm
Tissue enhanced (bone marrow, urinary bladder)
{'Ciliated cells': '222.0', 'Basal respiratory cells': '102.4', 'Club cells': '102.0', 'Ionocytes': '151.3', 'Mucus glandular cells': '266.5', 'Serous glandular cells': '115.3', 'Gastric mucus-secreting cells': '78.4', 'Proximal enterocytes': '42.9', 'Paneth cells': '17.5', 'Distal enterocytes': '30.6', 'Intestinal goblet cells': '32.1', 'Exocrine glandular cells': '-0.645', 'Basal prostatic cells': '87.8', 'Prostatic glandular cells': '11.6', 'Breast glandular cells': '0.196', 'Breast myoepithelial cells': '0.372', 'Glandular and luminal cells': '1464.3', 'Secretory cells': '239.6', 'Basal keratinocytes': '563.3', 'Suprabasal keratinocytes': '566.8', 'Basal squamous epithelial cells': '378.1', 'Squamous epithelial cells': '345.1', 'Alveolar cells type 1': '-0.009', 'Alveolar cells type 2': '-0.143', 'Salivary duct cells': '291.9', 'Ductal cells': '0.789', 'Hepatocytes': '0.134', 'Cholangiocytes': '21.0', 'Proximal tubular cells': '0.197', 'Distal tubular cells': '3.1', 'Collecting duct cells': '1.9', 'Mesothelial cells': '0.018', 'Sertoli cells': '0.075', 'Granulosa cells': '40.0', 'Enteroendocrine cells': '18.1', 'Pancreatic endocrine cells': '8.5', 'Leydig cells': '0.370', 'Excitatory neurons': '0.1', 'Inhibitory neurons': '0.3', 'Cone photoreceptor cells': '27.2', 'Rod photoreceptor cells': '15.7', 'Bipolar cells': '0.7', 'Horizontal cells': '1.9', 'Astrocytes': '1.9', 'Oligodendrocyte precursor cells': '1.9', 'Oligodendrocytes': '0.3', 'Microglial cells': '8.1', 'Muller glia cells': '5.5', 'Schwann cells': '0.011', 'Spermatogonia': '0.126', 'Spermatocytes': '-0.024', 'Early spermatids': '-0.035', 'Late spermatids': '-0.353', 'Oocytes': '5.1', 'Cytotrophoblasts': '8.5', 'Syncytiotrophoblasts': '19.6', 'Extravillous trophoblasts': '115.1', 'Endothelial cells': '144.9', 'Lymphatic endothelial cells': '37.6', 'Cardiomyocytes': '0.076', 'Skeletal myocytes': '0.359', 'Smooth muscle cells': '98.4', 'Adipocytes': '63.2', 'Melanocytes': '0.090', 'Fibroblasts': '83.8', 'Peritubular cells': '0.371', 'Endometrial stromal cells': '359.1', 'Ovarian stromal cells': '34.9', 'Undifferentiated cells': '12.6', 'T-cells': '778.2', 'B-cells': '95.4', 'Plasma cells': '280.9', 'Nk-cells': '411.5', 'Granulocytes': '1749.7', 'Monocytes': '1731.0', 'Macrophages': '777.5', 'Hofbauer cells': '176.5', 'Kupffer cells': '128.4', 'Dendritic cells': '129.5', 'Langerhans cells': '0.173', 'Erythroid cells': '0.154', 'Adipocytes (Subcutaneous)': '-0.425', 'Adipocytes (Visceral)': '-0.220', 'Breast glandular cells (progenitors)': '0.080', 'Adipocytes (Breast)': '-0.482', 'Colon enterocytes': '0.003', 'Colon enteroendocrine cells': '0.117', 'Enteric glia cells': '-0.193', 'Mitotic cells (Colon)': '0.097', 'Mitotic cells (Heart)': '0.354', 'Podocytes': '0.203', 'Ascending Loop of Henle cells': '0.015', 'Intercalated cells': '0.035', 'Cholangiocyte': '0.460', 'NK-cells (Liver)': '-0.192', 'Respiratory ciliated cells': '0.038', 'Mitotic cells (Lung)': '-0.111', 'NK-cells (Lung)': '0.178', 'B-cells (Lung)': '0.275', 'Alpha cells': '0.355', 'Beta cells': '0.236', 'Prostate glandular cells': '-0.177', 'Prostate basal glandular cells': '0.085', 'Urothelial cells': '0.154', 'Keratinocyte (other)': '0.355', 'Keratinocyte (granular)': '0.073', 'Hair cortex cells': '-0.229', 'Inner root sheath cells': '-0.173', 'Outer root sheath cells': '-0.203', 'Sebaceous gland cells': '-0.246', 'Eccrine sweat gland cells': '-0.219', 'Adipocytes (Skin)': '-0.360', 'Mitotic cells (Skin)': '0.009', 'Parietal cells': '-0.352', 'Chief cells': '-0.303', 'Gastric mucous cells': '-0.072', 'Gastric enteroendocrine cells': '-0.148', 'Mitotic cells (Stomach)': '0.111', 'Parafollicular cells': '0.005', 'Thyroid glandular cells': '-0.055', 'Mitotic cells (Thyroid)': '0.346', 'Adrenal cortex cells': '0.171', 'Adrenal medulla cells': '-0.001', 'Mitotic cells (Adrenal gland)': '-0.127', 'Minor salivary glandular cells': '0.610', 'Minor salivary gland ductal cells': '0.258', 'Minor salivary gland basal cells': '0.129', 'Mitotic cells (Minor salivary gland)': '0.169', 'Adipocytes (Minor salivary gland)': '0.167', 'Somatotropes': '-0.211', 'Lactotropes': '-0.389', 'Gonadotropes': '0.036', 'Corticotropes': '-0.232', 'Thyrotropes': '-0.083', 'Undifferentiated cells (Pituitary gland)': '0.183', 'Mitotic cells (Spleen)': '-0.149', 'Platelets': '-0.130', 'Erythrocytes': '-0.171', 'Hematopoietic stem cells': '-0.172', 'B-cells (Spleen)': '0.435', 'NK-cells (Spleen)': '0.215', 'Amygdala excitatory': '0.7', 'Cerebellar inhibitory': '2.7', 'Cge interneuron': '0.4', 'Deep-layer corticothalamic and 6b': '0.4', 'Deep-layer intratelencephalic': '0.5', 'Deep-layer near-projecting': '0.1', 'Eccentric medium spiny neuron': '0.5', 'Hippocampal ca1-3': '0.5', 'Hippocampal ca4': '1.3', 'Hippocampal dentate gyrus': '0.5', 'Lamp5-lhx6 and chandelier': '0.9', 'Lower rhombic lip': '1.3', 'Mammillary body': '0.2', 'Medium spiny neuron': '0.4', 'Mge interneuron': '0.1', 'Midbrain-derived inhibitory': '0.0', 'Miscellaneous': '0.2', 'Splatter': '1.2', 'Thalamic excitatory': '2.3', 'Upper rhombic lip': '0.1', 'Upper-layer intratelencephalic': '0.6', 'Astrocyte': '3.0', 'Bergmann glia': '2.5', 'Central nervous system macrophage': '24.4', 'Choroid plexus epithelial cell': '0.7', 'Committed oligodendrocyte precursor': '1.6', 'Ependymal cell': '2.1', 'Oligodendrocyte': '0.7', 'Oligodendrocyte precursor cell': '2.0', 'Endothelial cell': '51.5', 'Pericyte': '15.8', 'Vascular associated smooth muscle cell': '12.1', 'Fibroblast': '17.8', 'Leukocyte': '94.2', 'Basophil': '92.3', 'Eosinophil': '5.6', 'Neutrophil': '3039.7', 'Classical monocyte': '535.9', 'Non-classical monocyte': '75.6', 'Intermediate monocyte': '1330.1', 'T-reg': '572.8', 'GdT-cell': '11.5', 'MAIT T-cell': '1817.4', 'Memory CD4 T-cell': '11.1', 'Naive CD4 T-cell': '1624.2', 'Memory CD8 T-cell': '10.9', 'Naive CD8 T-cell': '1289.0', 'Memory B-cell': '4.6', 'Naive B-cell': '193.4', 'Plasmacytoid DC': '146.7', 'Myeloid DC': '771.0', 'NK-cell': '630.7', 'Total PBMC': '438.1', 'Vd2 gdTCR': '1321.8', 'Memory CD4 T-cell Th1\\/Th17': '4758.2', 'Memory CD4 T-cell Th17': '2777.6', 'Memory CD4 T-cell Th2': '2696.4', 'Non-Vd2 gdTCR': '697.3', 'Memory CD4 T-cell Th1': '3101.6', 'Memory CD4 T-cell TFH': '1767.2', 'Terminal effector memory CD4 T-cell': '586.0', 'Central memory CD8 T-cell': '1346.2', 'Effector memory CD8 T-cell': '1030.8', 'Terminal effector memory CD8 T-cell': '643.9', 'Non-switched memory B-cell': '183.3', 'Plasmablast': '108.3', 'Switched memory B-cell': '133.9', 'Exhausted memory B-cell': '184.7', 'Progenitor cell': '61.7', 'Memory T-reg': '1316.7', 'Naive CD4 T-cell activated': '1454.6', 'Naive CD8 T-cell activated': '1341.5', 'Naive T-reg': '813.0'}
2EQE, 2EQF, 2EQG, 2VFJ, 3DKB, 3OJ3, 3OJ4, 3VUW, 3VUX, 3VUY, 3ZJD, 3ZJE, 3ZJF, 3ZJG, 5LRX, 5V3B, 5V3P
{'Adipose Tissue': 71.89422425249168, 'Adrenal Gland': 18.808178294573644, 'Bladder': 27.82095238095238, 'Blood': 90.27551883745964, 'Blood Vessel': 22.304372284644195, 'Brain': 2.4634945495836487, 'Breast': 38.57104575163399, 'Cervix Uteri': 22.62152631578947, 'Colon': 29.911654685494224, 'Esophagus': 23.34145743944637, 'Fallopian Tube': 47.24111111111111, 'Heart': 12.724618118466898, 'Kidney': 16.023370786516853, 'Liver': 11.73166814159292, 'Lung': 103.90608996539792, 'Muscle': 5.374799252801993, 'Nerve': 35.55016155088853, 'Ovary': 131.08455555555557, 'Pancreas': 9.580134146341464, 'Pituitary': 13.757773851590104, 'Prostate': 30.354032653061225, 'Salivary Gland': 23.303753086419754, 'Skin': 55.29272028745163, 'Small Intestine': 50.19026737967914, 'Spleen': 57.31813278008299, 'Stomach': 21.495189415041786, 'Testis': 14.136614958448757, 'Thyroid': 23.792597243491574, 'Uterus': 30.784436619718313, 'Vagina': 27.45127564102564}
RNF41
MGYDVTRFQGDVDEDLICPICSGVLEEPVQAPHCEHAFCNACITQWFSQQQTCPVDRSVVTVAHLRPVPRIMRNMLSKLQIACDNAVFGCSAVVRLDNLMSHLSDCEHNPKRPVTCEQGCGLEMPKDELPNHNCIKHLRSVVQQQQTRIAELEKTSAEHKHQLAEQKRDIQLLKAYMRAIRSVNPNLQNLEETIEYNEILEWVNSLQPARVTRWGGMISTPDAVLQAVIKRSLVESGCPASIVNELIENAHERSWPQGLATLETRQMNRRYYENYVAKRIPGKQAVVVMACENQHMGDDMVQEPGLVMIFAHGVEEI
Homo sapiens
null
Low tissue specificity
{'Ciliated cells': '14.6', 'Basal respiratory cells': '12.6', 'Club cells': '15.6', 'Ionocytes': '10.3', 'Mucus glandular cells': '12.9', 'Serous glandular cells': '8.7', 'Gastric mucus-secreting cells': '9.4', 'Proximal enterocytes': '11.7', 'Paneth cells': '17.7', 'Distal enterocytes': '11.7', 'Intestinal goblet cells': '9.9', 'Exocrine glandular cells': '-0.742', 'Basal prostatic cells': '21.1', 'Prostatic glandular cells': '36.5', 'Breast glandular cells': '-0.132', 'Breast myoepithelial cells': '-0.183', 'Glandular and luminal cells': '14.8', 'Secretory cells': '20.6', 'Basal keratinocytes': '17.8', 'Suprabasal keratinocytes': '18.2', 'Basal squamous epithelial cells': '16.0', 'Squamous epithelial cells': '13.4', 'Alveolar cells type 1': '0.173', 'Alveolar cells type 2': '0.099', 'Salivary duct cells': '15.5', 'Ductal cells': '0.668', 'Hepatocytes': '0.309', 'Cholangiocytes': '24.8', 'Proximal tubular cells': '0.205', 'Distal tubular cells': '12.3', 'Collecting duct cells': '15.6', 'Mesothelial cells': '0.188', 'Sertoli cells': '-0.257', 'Granulosa cells': '15.4', 'Enteroendocrine cells': '21.2', 'Pancreatic endocrine cells': '17.0', 'Leydig cells': '-0.237', 'Excitatory neurons': '14.5', 'Inhibitory neurons': '15.0', 'Cone photoreceptor cells': '27.2', 'Rod photoreceptor cells': '16.2', 'Bipolar cells': '27.2', 'Horizontal cells': '16.4', 'Astrocytes': '10.5', 'Oligodendrocyte precursor cells': '13.7', 'Oligodendrocytes': '11.4', 'Microglial cells': '8.9', 'Muller glia cells': '24.1', 'Schwann cells': '0.094', 'Spermatogonia': '0.009', 'Spermatocytes': '0.185', 'Early spermatids': '0.461', 'Late spermatids': '0.344', 'Oocytes': '8.1', 'Cytotrophoblasts': '15.7', 'Syncytiotrophoblasts': '16.8', 'Extravillous trophoblasts': '18.7', 'Endothelial cells': '19.0', 'Lymphatic endothelial cells': '19.2', 'Cardiomyocytes': '0.629', 'Skeletal myocytes': '-0.061', 'Smooth muscle cells': '23.9', 'Adipocytes': '18.9', 'Melanocytes': '0.058', 'Fibroblasts': '18.5', 'Peritubular cells': '-0.112', 'Endometrial stromal cells': '13.9', 'Ovarian stromal cells': '16.0', 'Undifferentiated cells': '15.9', 'T-cells': '17.9', 'B-cells': '41.7', 'Plasma cells': '13.8', 'Nk-cells': '18.2', 'Granulocytes': '16.2', 'Monocytes': '33.0', 'Macrophages': '25.1', 'Hofbauer cells': '21.6', 'Kupffer cells': '25.2', 'Dendritic cells': '24.1', 'Langerhans cells': '0.179', 'Erythroid cells': '-0.009', 'Adipocytes (Subcutaneous)': '0.529', 'Adipocytes (Visceral)': '0.412', 'Breast glandular cells (progenitors)': '-0.102', 'Adipocytes (Breast)': '0.500', 'Colon enterocytes': '-0.148', 'Colon enteroendocrine cells': '0.209', 'Enteric glia cells': '-0.035', 'Mitotic cells (Colon)': '-0.183', 'Mitotic cells (Heart)': '0.469', 'Podocytes': '-0.011', 'Ascending Loop of Henle cells': '0.408', 'Intercalated cells': '0.001', 'Cholangiocyte': '0.315', 'NK-cells (Liver)': '-0.302', 'Respiratory ciliated cells': '-0.086', 'Mitotic cells (Lung)': '-0.007', 'NK-cells (Lung)': '-0.080', 'B-cells (Lung)': '-0.195', 'Alpha cells': '0.421', 'Beta cells': '0.238', 'Prostate glandular cells': '0.530', 'Prostate basal glandular cells': '0.075', 'Urothelial cells': '-0.162', 'Keratinocyte (other)': '-0.027', 'Keratinocyte (granular)': '-0.060', 'Hair cortex cells': '0.129', 'Inner root sheath cells': '0.160', 'Outer root sheath cells': '0.220', 'Sebaceous gland cells': '0.212', 'Eccrine sweat gland cells': '0.059', 'Adipocytes (Skin)': '0.176', 'Mitotic cells (Skin)': '0.205', 'Parietal cells': '-0.716', 'Chief cells': '-0.576', 'Gastric mucous cells': '-0.481', 'Gastric enteroendocrine cells': '-0.456', 'Mitotic cells (Stomach)': '-0.040', 'Parafollicular cells': '0.087', 'Thyroid glandular cells': '0.441', 'Mitotic cells (Thyroid)': '-0.103', 'Adrenal cortex cells': '0.402', 'Adrenal medulla cells': '-0.037', 'Mitotic cells (Adrenal gland)': '0.184', 'Minor salivary glandular cells': '0.599', 'Minor salivary gland ductal cells': '0.113', 'Minor salivary gland basal cells': '0.255', 'Mitotic cells (Minor salivary gland)': '0.261', 'Adipocytes (Minor salivary gland)': '0.251', 'Somatotropes': '-0.020', 'Lactotropes': '0.135', 'Gonadotropes': '-0.156', 'Corticotropes': '0.081', 'Thyrotropes': '0.211', 'Undifferentiated cells (Pituitary gland)': '0.081', 'Mitotic cells (Spleen)': '-0.246', 'Platelets': '-0.144', 'Erythrocytes': '-0.115', 'Hematopoietic stem cells': '-0.258', 'B-cells (Spleen)': '0.520', 'NK-cells (Spleen)': '0.303', 'Amygdala excitatory': '20.7', 'Cerebellar inhibitory': '17.3', 'Cge interneuron': '28.1', 'Deep-layer corticothalamic and 6b': '21.1', 'Deep-layer intratelencephalic': '23.0', 'Deep-layer near-projecting': '25.0', 'Eccentric medium spiny neuron': '26.6', 'Hippocampal ca1-3': '18.8', 'Hippocampal ca4': '20.9', 'Hippocampal dentate gyrus': '21.8', 'Lamp5-lhx6 and chandelier': '27.3', 'Lower rhombic lip': '15.4', 'Mammillary body': '18.3', 'Medium spiny neuron': '19.7', 'Mge interneuron': '23.7', 'Midbrain-derived inhibitory': '23.5', 'Miscellaneous': '19.2', 'Splatter': '20.2', 'Thalamic excitatory': '23.0', 'Upper rhombic lip': '24.3', 'Upper-layer intratelencephalic': '23.2', 'Astrocyte': '23.4', 'Bergmann glia': '24.2', 'Central nervous system macrophage': '46.4', 'Choroid plexus epithelial cell': '33.2', 'Committed oligodendrocyte precursor': '21.4', 'Ependymal cell': '17.6', 'Oligodendrocyte': '18.0', 'Oligodendrocyte precursor cell': '17.0', 'Endothelial cell': '21.3', 'Pericyte': '19.2', 'Vascular associated smooth muscle cell': '19.7', 'Fibroblast': '17.9', 'Leukocyte': '20.5', 'Basophil': '101.0', 'Eosinophil': '100.1', 'Neutrophil': '108.1', 'Classical monocyte': '37.8', 'Non-classical monocyte': '27.0', 'Intermediate monocyte': '88.5', 'T-reg': '52.2', 'GdT-cell': '27.7', 'MAIT T-cell': '76.2', 'Memory CD4 T-cell': '23.1', 'Naive CD4 T-cell': '22.2', 'Memory CD8 T-cell': '24.3', 'Naive CD8 T-cell': '19.0', 'Memory B-cell': '50.5', 'Naive B-cell': '61.4', 'Plasmacytoid DC': '61.0', 'Myeloid DC': '91.5', 'NK-cell': '25.4', 'Total PBMC': '64.0', 'Vd2 gdTCR': '59.8', 'Memory CD4 T-cell Th1\\/Th17': '19.9', 'Memory CD4 T-cell Th17': '20.1', 'Memory CD4 T-cell Th2': '20.6', 'Non-Vd2 gdTCR': '70.2', 'Memory CD4 T-cell Th1': '21.4', 'Memory CD4 T-cell TFH': '22.0', 'Terminal effector memory CD4 T-cell': '80.2', 'Central memory CD8 T-cell': '50.3', 'Effector memory CD8 T-cell': '59.1', 'Terminal effector memory CD8 T-cell': '64.7', 'Non-switched memory B-cell': '127.8', 'Plasmablast': '64.9', 'Switched memory B-cell': '122.1', 'Exhausted memory B-cell': '121.2', 'Progenitor cell': '68.1', 'Memory T-reg': '22.6', 'Naive CD4 T-cell activated': '25.8', 'Naive CD8 T-cell activated': '29.6', 'Naive T-reg': '23.9'}
2FZP, 2GWF
{'Adipose Tissue': 21.080775747508305, 'Adrenal Gland': 18.237453488372093, 'Bladder': 20.031428571428577, 'Blood': 12.89670828848224, 'Blood Vessel': 26.68823820224719, 'Brain': 20.08383573050719, 'Breast': 19.03358605664488, 'Cervix Uteri': 19.87684210526316, 'Colon': 18.93227599486521, 'Esophagus': 19.29166089965398, 'Fallopian Tube': 22.30333333333333, 'Heart': 10.6448837398374, 'Kidney': 9.84311235955056, 'Liver': 5.157323008849557, 'Lung': 21.83735813148789, 'Muscle': 12.636986301369864, 'Nerve': 22.00962843295638, 'Ovary': 20.94172222222222, 'Pancreas': 5.733323170731707, 'Pituitary': 22.92886925795053, 'Prostate': 28.339469387755106, 'Salivary Gland': 12.39419135802469, 'Skin': 17.10487285793256, 'Small Intestine': 15.741374331550803, 'Spleen': 16.730452282157678, 'Stomach': 12.853256267409472, 'Testis': 17.352686980609416, 'Thyroid': 21.194781010719755, 'Uterus': 23.89823943661972, 'Vagina': 16.735717948717948}
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[90.72, 94.28, 95.95, 95.17, 95.01, 93.97, 94.92, 96.14, 93.54, 91.02, 91.08, 94.3, 94.86, 93.97, 93.87, 96.67, 97.4, 97.82, 96.08, 96.01, 97.06, 96.6, 97.07, 97.6, 97.71, 96.15, 95.46, 96.62, 96.37, 96.3, 94.23, 89.25, 89.78, 93.1, 94.06, 95.87, 96.78, 97.36, 97.6, 95.81, 96.17, 96.81, 95.22, 93.84, 94.7, 94.49, 93.26, 91.89, 91.07, 90.5, 90.62, 94.01, 94.66, 94.13, 94.38, 95.41, 92.72, 91.83, 90.42, 89.95, 85.1, 86.93, 87.72, 89.33, 93.14, 94.76, 94.92, 96.11, 95.47, 95.9, 95.87, 95.56, 95.65, 95.94, 95.87, 96.31, 95.37, 95.8, 96.61, 97.49, 97.4, 96.62, 95.72, 93.02, 93.68, 92.38, 91.44, 89.62, 90.86, 94.65, 93.56, 94.68, 95.88, 96.55, 96.69, 96.06, 94.44, 96.29, 95.61, 92.86, 94.72, 95.83, 93.56, 91.11, 90.31, 93.4, 88.79, 91.96, 92.76, 89.6, 89.61, 89.59, 90.22, 90.96, 93.03, 92.79, 88.54, 86.77, 85.95, 91.66, 89.99, 92.08, 92.63, 88.65, 91.06, 88.01, 89.41, 91.26, 88.73, 88.2, 90.96, 92.14, 92.85, 93.87, 94.27, 93.64, 94.1, 95.43, 96.12, 96.0, 96.2, 96.93, 97.2, 97.7, 98.0, 97.98, 97.96, 98.28, 98.43, 97.83, 98.13, 98.4, 97.88, 97.75, 97.83, 97.66, 97.36, 97.61, 97.29, 93.6, 95.05, 96.7, 90.74, 87.4, 94.34, 92.06, 81.63, 86.96, 88.69, 82.15, 75.41, 83.69, 77.81, 73.14, 71.07, 72.31, 69.05, 68.55, 69.94, 70.2, 66.26, 67.88, 75.31, 71.2, 71.28, 72.77, 64.65, 62.31, 63.48, 66.17, 61.9, 66.85, 73.01, 75.59, 76.9, 80.59, 83.94, 88.73, 90.31, 90.08, 92.76, 95.04, 94.9, 94.32, 95.4, 96.04, 95.67, 96.83, 95.79, 94.46, 94.41, 93.03, 92.37, 91.11, 90.41, 91.93, 94.48, 95.19, 94.22, 95.18, 95.03, 95.71, 94.85, 96.75, 95.34, 96.27, 96.67, 97.08, 97.2, 97.44, 97.1, 97.3, 97.0, 96.07, 95.56, 95.24, 94.06, 94.75, 92.1, 89.12, 87.39, 92.54, 94.9, 93.55, 93.55, 96.88, 96.79, 94.4, 96.08, 95.7, 94.59, 93.77, 92.29, 93.38, 93.85, 92.59, 90.56, 92.13, 92.07, 88.47, 89.89, 89.55, 91.42, 91.44, 91.51, 89.42, 91.09, 92.4, 87.77, 88.11, 90.14, 85.88, 86.06, 92.24, 95.49, 95.35, 96.35, 97.23, 96.95, 96.57, 94.1, 93.65, 95.39, 96.8, 97.47, 97.41, 97.35, 96.55, 95.55, 91.31, 89.05, 91.81, 93.23, 88.91, 91.77, 91.56, 85.6, 81.97, 89.25, 92.37, 90.95, 89.93, 87.58, 91.83, 95.34, 95.52, 97.25, 96.3, 97.11, 96.47, 94.64, 93.58, 93.54, 95.65, 93.15, 88.7, 86.24]
[0.62, 0.25, 0.2, 0.53, 0.34, 0.81, 0.2, 0.09, 0.6, 0.76, 0.96, 0.19, 0.57, 0.78, 0.7, 0.05, 0.28, 0.01, 0.5, 0.35, 0.35, 0.63, 0.06, 0.0, 0.02, 0.33, 0.77, 0.19, 0.12, 0.17, 0.03, 0.33, 0.85, 0.2, 0.67, 0.29, 0.11, 0.01, 0.01, 0.36, 0.54, 0.07, 0.01, 0.44, 0.61, 0.36, 0.09, 0.76, 0.9, 0.54, 0.57, 0.29, 0.03, 0.33, 0.5, 0.5, 0.81, 0.27, 0.75, 0.04, 0.31, 0.53, 0.91, 0.53, 0.18, 0.69, 0.76, 0.06, 0.46, 0.74, 0.66, 0.17, 0.51, 0.41, 0.51, 0.05, 0.24, 0.67, 0.17, 0.45, 0.0, 0.29, 0.02, 0.47, 0.09, 0.44, 0.91, 0.57, 0.52, 0.09, 0.84, 0.27, 0.47, 0.2, 0.47, 0.12, 0.51, 0.54, 0.01, 0.72, 0.48, 0.22, 0.2, 0.64, 0.74, 0.03, 0.71, 0.39, 0.2, 0.18, 0.8, 0.4, 0.72, 0.15, 0.57, 0.08, 0.9, 0.82, 0.78, 0.13, 0.61, 0.34, 0.76, 0.11, 0.35, 0.42, 0.54, 0.53, 0.42, 0.82, 0.84, 0.23, 0.58, 0.15, 0.58, 0.73, 0.28, 0.44, 0.67, 0.56, 0.31, 0.48, 0.58, 0.67, 0.55, 0.53, 0.47, 0.59, 0.54, 0.48, 0.5, 0.53, 0.63, 0.64, 0.41, 0.6, 0.53, 0.47, 0.58, 0.74, 0.66, 0.54, 0.52, 0.49, 0.45, 0.54, 0.64, 0.59, 0.51, 0.52, 0.65, 0.56, 0.59, 0.53, 0.44, 0.59, 0.46, 0.63, 0.51, 0.57, 0.29, 0.66, 0.82, 0.47, 0.6, 0.79, 0.3, 0.46, 0.61, 0.49, 0.4, 0.66, 0.51, 0.34, 0.32, 0.49, 0.48, 0.53, 0.1, 0.3, 0.71, 0.04, 0.01, 0.69, 0.59, 0.07, 0.61, 0.4, 0.09, 0.56, 0.13, 0.46, 0.63, 0.11, 0.93, 0.15, 0.14, 0.28, 0.13, 0.64, 0.06, 0.6, 0.68, 0.69, 0.28, 0.25, 0.52, 0.43, 0.02, 0.38, 0.66, 0.08, 0.0, 0.57, 0.65, 0.23, 0.6, 0.1, 0.09, 0.73, 0.5, 0.03, 0.04, 0.56, 0.48, 0.0, 0.13, 0.5, 0.07, 0.01, 0.26, 0.29, 0.74, 0.25, 0.07, 0.07, 0.77, 0.04, 0.0, 0.38, 0.49, 0.61, 0.78, 0.22, 0.11, 0.66, 0.77, 0.12, 0.57, 0.8, 0.5, 0.07, 0.57, 0.55, 0.08, 0.33, 0.08, 0.1, 0.19, 0.02, 0.51, 0.76, 0.3, 0.31, 0.0, 0.0, 0.01, 0.02, 0.02, 0.08, 0.22, 0.27, 0.01, 0.73, 0.65, 0.16, 0.46, 0.85, 0.52, 0.05, 0.2, 0.36, 0.82, 0.14, 0.0, 0.01, 0.0, 0.0, 0.04, 0.04, 0.62, 0.52, 0.18, 0.07, 0.41, 0.62, 0.66]
ZnF_A20
component of a ubiquitin-editing protein complex, comprising also RNF11, ITCH and TAX1BP1
null
null
IKBKG, ITCH, YWHAH, TRAF6, RIPK1, TRAF2, TNIP1, TAX1BP1, RNF11, YWHAZ
UBE2N, UBE2D3, RIPK1
11, 48, 63
null
UBE2N, UBE2D3
Homodimer
null
74.507911
0.508165
91.714763
0.404479
2,315
P21580
Q9NR96
30277474
UbiBrowser
TNFAIP3
MAEQVLPQALYLSNMRKAVKIRERTPEDIFKPTNGIIHHFKTMHRYTLEMFRTCQFCPQFREIIHKALIDRNIQATLESQKKLNWCREVRKLVALKTNGDGNCLMHATSQYMWGVQDTDLVLRKALFSTLKETDTRNFKFRWQLESLKSQEFVETGLCYDTRNWNDEWDNLIKMASTDTPMARSGLQYNSLEEIHIFVLCNILRRPIIVISDKMLRSLESGSNFAPLKVGGIYLPLHWPAQECYRYPIVLGYDSHHFVPLVTLKDSGPEIRAVPLVNRDRGRFEDLKVHFLTDPENEMKEKLLKEYLMVIEIPVQGWDHGTTHLINAAKLDEANLPKEINLVDDYFELVQHEYKKWQENSEQGRREGHAQNPMEPSVPQLSLMDVKCETPNCPFFMSVNTQPLCHECSERRQKNQNKLPKLNSKPGPEGLPGMALGASRGEAYEPLAWNPEESTGGPHSAPPTAPSPFLFSETTAMKCRSPGCPFTLNVQHNGFCERCHNARQLHASHAPDHTRHLDPGKCQACLQDVTRTFNGICSTCFKRTTAEASSSLSTSLPPSCHQRSKSDPSRLVRSPSPHSCHRAGNDAPAGCLSQAARTPGDRTGTSKCRKAGCVYFGTPENKGFCTLCFIEYRENKHFAAASGKVSPTASRFQNTIPCLGRECGTLGSTMFEGYCQKCFIEAQNQRFHEAKRTEEQLRSSQRRDVPRTTQSTSRPKCARASCKNILACRSEELCMECQHPNQRMGPGAHRGEPAPEDPPKQRCRAPACDHFGNAKCNGYCNECFQFKQMYG
Homo sapiens
Cytoplasm, Nucleus, Lysosome, Cytoplasm
Tissue enhanced (bone marrow, urinary bladder)
{'Ciliated cells': '222.0', 'Basal respiratory cells': '102.4', 'Club cells': '102.0', 'Ionocytes': '151.3', 'Mucus glandular cells': '266.5', 'Serous glandular cells': '115.3', 'Gastric mucus-secreting cells': '78.4', 'Proximal enterocytes': '42.9', 'Paneth cells': '17.5', 'Distal enterocytes': '30.6', 'Intestinal goblet cells': '32.1', 'Exocrine glandular cells': '-0.645', 'Basal prostatic cells': '87.8', 'Prostatic glandular cells': '11.6', 'Breast glandular cells': '0.196', 'Breast myoepithelial cells': '0.372', 'Glandular and luminal cells': '1464.3', 'Secretory cells': '239.6', 'Basal keratinocytes': '563.3', 'Suprabasal keratinocytes': '566.8', 'Basal squamous epithelial cells': '378.1', 'Squamous epithelial cells': '345.1', 'Alveolar cells type 1': '-0.009', 'Alveolar cells type 2': '-0.143', 'Salivary duct cells': '291.9', 'Ductal cells': '0.789', 'Hepatocytes': '0.134', 'Cholangiocytes': '21.0', 'Proximal tubular cells': '0.197', 'Distal tubular cells': '3.1', 'Collecting duct cells': '1.9', 'Mesothelial cells': '0.018', 'Sertoli cells': '0.075', 'Granulosa cells': '40.0', 'Enteroendocrine cells': '18.1', 'Pancreatic endocrine cells': '8.5', 'Leydig cells': '0.370', 'Excitatory neurons': '0.1', 'Inhibitory neurons': '0.3', 'Cone photoreceptor cells': '27.2', 'Rod photoreceptor cells': '15.7', 'Bipolar cells': '0.7', 'Horizontal cells': '1.9', 'Astrocytes': '1.9', 'Oligodendrocyte precursor cells': '1.9', 'Oligodendrocytes': '0.3', 'Microglial cells': '8.1', 'Muller glia cells': '5.5', 'Schwann cells': '0.011', 'Spermatogonia': '0.126', 'Spermatocytes': '-0.024', 'Early spermatids': '-0.035', 'Late spermatids': '-0.353', 'Oocytes': '5.1', 'Cytotrophoblasts': '8.5', 'Syncytiotrophoblasts': '19.6', 'Extravillous trophoblasts': '115.1', 'Endothelial cells': '144.9', 'Lymphatic endothelial cells': '37.6', 'Cardiomyocytes': '0.076', 'Skeletal myocytes': '0.359', 'Smooth muscle cells': '98.4', 'Adipocytes': '63.2', 'Melanocytes': '0.090', 'Fibroblasts': '83.8', 'Peritubular cells': '0.371', 'Endometrial stromal cells': '359.1', 'Ovarian stromal cells': '34.9', 'Undifferentiated cells': '12.6', 'T-cells': '778.2', 'B-cells': '95.4', 'Plasma cells': '280.9', 'Nk-cells': '411.5', 'Granulocytes': '1749.7', 'Monocytes': '1731.0', 'Macrophages': '777.5', 'Hofbauer cells': '176.5', 'Kupffer cells': '128.4', 'Dendritic cells': '129.5', 'Langerhans cells': '0.173', 'Erythroid cells': '0.154', 'Adipocytes (Subcutaneous)': '-0.425', 'Adipocytes (Visceral)': '-0.220', 'Breast glandular cells (progenitors)': '0.080', 'Adipocytes (Breast)': '-0.482', 'Colon enterocytes': '0.003', 'Colon enteroendocrine cells': '0.117', 'Enteric glia cells': '-0.193', 'Mitotic cells (Colon)': '0.097', 'Mitotic cells (Heart)': '0.354', 'Podocytes': '0.203', 'Ascending Loop of Henle cells': '0.015', 'Intercalated cells': '0.035', 'Cholangiocyte': '0.460', 'NK-cells (Liver)': '-0.192', 'Respiratory ciliated cells': '0.038', 'Mitotic cells (Lung)': '-0.111', 'NK-cells (Lung)': '0.178', 'B-cells (Lung)': '0.275', 'Alpha cells': '0.355', 'Beta cells': '0.236', 'Prostate glandular cells': '-0.177', 'Prostate basal glandular cells': '0.085', 'Urothelial cells': '0.154', 'Keratinocyte (other)': '0.355', 'Keratinocyte (granular)': '0.073', 'Hair cortex cells': '-0.229', 'Inner root sheath cells': '-0.173', 'Outer root sheath cells': '-0.203', 'Sebaceous gland cells': '-0.246', 'Eccrine sweat gland cells': '-0.219', 'Adipocytes (Skin)': '-0.360', 'Mitotic cells (Skin)': '0.009', 'Parietal cells': '-0.352', 'Chief cells': '-0.303', 'Gastric mucous cells': '-0.072', 'Gastric enteroendocrine cells': '-0.148', 'Mitotic cells (Stomach)': '0.111', 'Parafollicular cells': '0.005', 'Thyroid glandular cells': '-0.055', 'Mitotic cells (Thyroid)': '0.346', 'Adrenal cortex cells': '0.171', 'Adrenal medulla cells': '-0.001', 'Mitotic cells (Adrenal gland)': '-0.127', 'Minor salivary glandular cells': '0.610', 'Minor salivary gland ductal cells': '0.258', 'Minor salivary gland basal cells': '0.129', 'Mitotic cells (Minor salivary gland)': '0.169', 'Adipocytes (Minor salivary gland)': '0.167', 'Somatotropes': '-0.211', 'Lactotropes': '-0.389', 'Gonadotropes': '0.036', 'Corticotropes': '-0.232', 'Thyrotropes': '-0.083', 'Undifferentiated cells (Pituitary gland)': '0.183', 'Mitotic cells (Spleen)': '-0.149', 'Platelets': '-0.130', 'Erythrocytes': '-0.171', 'Hematopoietic stem cells': '-0.172', 'B-cells (Spleen)': '0.435', 'NK-cells (Spleen)': '0.215', 'Amygdala excitatory': '0.7', 'Cerebellar inhibitory': '2.7', 'Cge interneuron': '0.4', 'Deep-layer corticothalamic and 6b': '0.4', 'Deep-layer intratelencephalic': '0.5', 'Deep-layer near-projecting': '0.1', 'Eccentric medium spiny neuron': '0.5', 'Hippocampal ca1-3': '0.5', 'Hippocampal ca4': '1.3', 'Hippocampal dentate gyrus': '0.5', 'Lamp5-lhx6 and chandelier': '0.9', 'Lower rhombic lip': '1.3', 'Mammillary body': '0.2', 'Medium spiny neuron': '0.4', 'Mge interneuron': '0.1', 'Midbrain-derived inhibitory': '0.0', 'Miscellaneous': '0.2', 'Splatter': '1.2', 'Thalamic excitatory': '2.3', 'Upper rhombic lip': '0.1', 'Upper-layer intratelencephalic': '0.6', 'Astrocyte': '3.0', 'Bergmann glia': '2.5', 'Central nervous system macrophage': '24.4', 'Choroid plexus epithelial cell': '0.7', 'Committed oligodendrocyte precursor': '1.6', 'Ependymal cell': '2.1', 'Oligodendrocyte': '0.7', 'Oligodendrocyte precursor cell': '2.0', 'Endothelial cell': '51.5', 'Pericyte': '15.8', 'Vascular associated smooth muscle cell': '12.1', 'Fibroblast': '17.8', 'Leukocyte': '94.2', 'Basophil': '92.3', 'Eosinophil': '5.6', 'Neutrophil': '3039.7', 'Classical monocyte': '535.9', 'Non-classical monocyte': '75.6', 'Intermediate monocyte': '1330.1', 'T-reg': '572.8', 'GdT-cell': '11.5', 'MAIT T-cell': '1817.4', 'Memory CD4 T-cell': '11.1', 'Naive CD4 T-cell': '1624.2', 'Memory CD8 T-cell': '10.9', 'Naive CD8 T-cell': '1289.0', 'Memory B-cell': '4.6', 'Naive B-cell': '193.4', 'Plasmacytoid DC': '146.7', 'Myeloid DC': '771.0', 'NK-cell': '630.7', 'Total PBMC': '438.1', 'Vd2 gdTCR': '1321.8', 'Memory CD4 T-cell Th1\\/Th17': '4758.2', 'Memory CD4 T-cell Th17': '2777.6', 'Memory CD4 T-cell Th2': '2696.4', 'Non-Vd2 gdTCR': '697.3', 'Memory CD4 T-cell Th1': '3101.6', 'Memory CD4 T-cell TFH': '1767.2', 'Terminal effector memory CD4 T-cell': '586.0', 'Central memory CD8 T-cell': '1346.2', 'Effector memory CD8 T-cell': '1030.8', 'Terminal effector memory CD8 T-cell': '643.9', 'Non-switched memory B-cell': '183.3', 'Plasmablast': '108.3', 'Switched memory B-cell': '133.9', 'Exhausted memory B-cell': '184.7', 'Progenitor cell': '61.7', 'Memory T-reg': '1316.7', 'Naive CD4 T-cell activated': '1454.6', 'Naive CD8 T-cell activated': '1341.5', 'Naive T-reg': '813.0'}
2EQE, 2EQF, 2EQG, 2VFJ, 3DKB, 3OJ3, 3OJ4, 3VUW, 3VUX, 3VUY, 3ZJD, 3ZJE, 3ZJF, 3ZJG, 5LRX, 5V3B, 5V3P
{'Adipose Tissue': 71.89422425249168, 'Adrenal Gland': 18.808178294573644, 'Bladder': 27.82095238095238, 'Blood': 90.27551883745964, 'Blood Vessel': 22.304372284644195, 'Brain': 2.4634945495836487, 'Breast': 38.57104575163399, 'Cervix Uteri': 22.62152631578947, 'Colon': 29.911654685494224, 'Esophagus': 23.34145743944637, 'Fallopian Tube': 47.24111111111111, 'Heart': 12.724618118466898, 'Kidney': 16.023370786516853, 'Liver': 11.73166814159292, 'Lung': 103.90608996539792, 'Muscle': 5.374799252801993, 'Nerve': 35.55016155088853, 'Ovary': 131.08455555555557, 'Pancreas': 9.580134146341464, 'Pituitary': 13.757773851590104, 'Prostate': 30.354032653061225, 'Salivary Gland': 23.303753086419754, 'Skin': 55.29272028745163, 'Small Intestine': 50.19026737967914, 'Spleen': 57.31813278008299, 'Stomach': 21.495189415041786, 'Testis': 14.136614958448757, 'Thyroid': 23.792597243491574, 'Uterus': 30.784436619718313, 'Vagina': 27.45127564102564}
TLR9
MGFCRSALHPLSLLVQAIMLAMTLALGTLPAFLPCELQPHGLVNCNWLFLKSVPHFSMAAPRGNVTSLSLSSNRIHHLHDSDFAHLPSLRHLNLKWNCPPVGLSPMHFPCHMTIEPSTFLAVPTLEELNLSYNNIMTVPALPKSLISLSLSHTNILMLDSASLAGLHALRFLFMDGNCYYKNPCRQALEVAPGALLGLGNLTHLSLKYNNLTVVPRNLPSSLEYLLLSYNRIVKLAPEDLANLTALRVLDVGGNCRRCDHAPNPCMECPRHFPQLHPDTFSHLSRLEGLVLKDSSLSWLNASWFRGLGNLRVLDLSENFLYKCITKTKAFQGLTQLRKLNLSFNYQKRVSFAHLSLAPSFGSLVALKELDMHGIFFRSLDETTLRPLARLPMLQTLRLQMNFINQAQLGIFRAFPGLRYVDLSDNRISGASELTATMGEADGGEKVWLQPGDLAPAPVDTPSSEDFRPNCSTLNFTLDLSRNNLVTVQPEMFAQLSHLQCLRLSHNCISQAVNGSQFLPLTGLQVLDLSHNKLDLYHEHSFTELPRLEALDLSYNSQPFGMQGVGHNFSFVAHLRTLRHLSLAHNNIHSQVSQQLCSTSLRALDFSGNALGHMWAEGDLYLHFFQGLSGLIWLDLSQNRLHTLLPQTLRNLPKSLQVLRLRDNYLAFFKWWSLHFLPKLEVLDLAGNQLKALTNGSLPAGTRLRRLDVSCNSISFVAPGFFSKAKELRELNLSANALKTVDHSWFGPLASALQILDVSANPLHCACGAAFMDFLLEVQAAVPGLPSRVKCGSPGQLQGLSIFAQDLRLCLDEALSWDCFALSLLAVALGLGVPMLHHLCGWDLWYCFHLCLAWLPWRGRQSGRDEDALPYDAFVVFDKTQSAVADWVYNELRGQLEECRGRWALRLCLEERDWLPGKTLFENLWASVYGSRKTLFVLAHTDRVSGLLRASFLLAQQRLLEDRKDVVVLVILSPDGRRSRYVRLRQRLCRQSVLLWPHQPSGQRSFWAQLGMALTRDNHHFYNRNFCQGPTAE
Homo sapiens
Endoplasmic reticulum membrane, Early endosome membrane, Lysosome, Cytoplasmic vesicle, phagosome, Golgi apparatus membrane
Tissue enhanced (lymphoid)
{'Ciliated cells': '0.0', 'Basal respiratory cells': '0.0', 'Club cells': '0.0', 'Ionocytes': '0.0', 'Mucus glandular cells': '0.0', 'Serous glandular cells': '0.0', 'Gastric mucus-secreting cells': '0.0', 'Proximal enterocytes': '0.0', 'Paneth cells': '0.0', 'Distal enterocytes': '0.0', 'Intestinal goblet cells': '0.0', 'Exocrine glandular cells': '-0.269', 'Basal prostatic cells': '0.0', 'Prostatic glandular cells': '0.0', 'Breast glandular cells': '0.372', 'Breast myoepithelial cells': '0.347', 'Glandular and luminal cells': '0.0', 'Secretory cells': '0.0', 'Basal keratinocytes': '0.0', 'Suprabasal keratinocytes': '0.0', 'Basal squamous epithelial cells': '0.0', 'Squamous epithelial cells': '0.0', 'Alveolar cells type 1': '0.004', 'Alveolar cells type 2': '-0.335', 'Salivary duct cells': '0.0', 'Ductal cells': '0.397', 'Hepatocytes': '0.084', 'Cholangiocytes': '0.0', 'Proximal tubular cells': '0.067', 'Distal tubular cells': '0.0', 'Collecting duct cells': '0.0', 'Mesothelial cells': '0.389', 'Sertoli cells': '0.518', 'Granulosa cells': '0.0', 'Enteroendocrine cells': '0.0', 'Pancreatic endocrine cells': '0.0', 'Leydig cells': '0.328', 'Excitatory neurons': '0.3', 'Inhibitory neurons': '0.3', 'Cone photoreceptor cells': '0.0', 'Rod photoreceptor cells': '0.0', 'Bipolar cells': '0.0', 'Horizontal cells': '0.0', 'Astrocytes': '0.0', 'Oligodendrocyte precursor cells': '0.0', 'Oligodendrocytes': '0.2', 'Microglial cells': '0.9', 'Muller glia cells': '0.0', 'Schwann cells': '0.125', 'Spermatogonia': '0.125', 'Spermatocytes': '-0.234', 'Early spermatids': '-0.564', 'Late spermatids': '-0.460', 'Oocytes': '0.0', 'Cytotrophoblasts': '0.0', 'Syncytiotrophoblasts': '0.0', 'Extravillous trophoblasts': '0.0', 'Endothelial cells': '0.0', 'Lymphatic endothelial cells': '0.0', 'Cardiomyocytes': '0.203', 'Skeletal myocytes': '0.118', 'Smooth muscle cells': '0.0', 'Adipocytes': '0.0', 'Melanocytes': '-0.294', 'Fibroblasts': '0.0', 'Peritubular cells': '0.368', 'Endometrial stromal cells': '0.0', 'Ovarian stromal cells': '0.0', 'Undifferentiated cells': '0.1', 'T-cells': '0.0', 'B-cells': '3.4', 'Plasma cells': '3.2', 'Nk-cells': '0.0', 'Granulocytes': '0.0', 'Monocytes': '0.0', 'Macrophages': '0.0', 'Hofbauer cells': '0.0', 'Kupffer cells': '0.0', 'Dendritic cells': '0.0', 'Langerhans cells': '-0.122', 'Erythroid cells': '0.033', 'Adipocytes (Subcutaneous)': '-0.075', 'Adipocytes (Visceral)': '-0.233', 'Breast glandular cells (progenitors)': '0.327', 'Adipocytes (Breast)': '-0.371', 'Colon enterocytes': '-0.152', 'Colon enteroendocrine cells': '0.141', 'Enteric glia cells': '0.568', 'Mitotic cells (Colon)': '-0.197', 'Mitotic cells (Heart)': '0.067', 'Podocytes': '-0.014', 'Ascending Loop of Henle cells': '0.256', 'Intercalated cells': '0.011', 'Cholangiocyte': '0.206', 'NK-cells (Liver)': '-0.004', 'Respiratory ciliated cells': '0.004', 'Mitotic cells (Lung)': '-0.169', 'NK-cells (Lung)': '0.184', 'B-cells (Lung)': '0.188', 'Alpha cells': '0.277', 'Beta cells': '0.157', 'Prostate glandular cells': '-0.265', 'Prostate basal glandular cells': '-0.054', 'Urothelial cells': '0.151', 'Keratinocyte (other)': '-0.279', 'Keratinocyte (granular)': '-0.132', 'Hair cortex cells': '0.020', 'Inner root sheath cells': '0.046', 'Outer root sheath cells': '0.118', 'Sebaceous gland cells': '-0.031', 'Eccrine sweat gland cells': '0.271', 'Adipocytes (Skin)': '0.245', 'Mitotic cells (Skin)': '-0.157', 'Parietal cells': '-0.559', 'Chief cells': '-0.512', 'Gastric mucous cells': '-0.309', 'Gastric enteroendocrine cells': '-0.338', 'Mitotic cells (Stomach)': '-0.086', 'Parafollicular cells': '0.016', 'Thyroid glandular cells': '-0.049', 'Mitotic cells (Thyroid)': '0.164', 'Adrenal cortex cells': '0.209', 'Adrenal medulla cells': '-0.002', 'Mitotic cells (Adrenal gland)': '-0.056', 'Minor salivary glandular cells': '0.357', 'Minor salivary gland ductal cells': '0.193', 'Minor salivary gland basal cells': '-0.194', 'Mitotic cells (Minor salivary gland)': '-0.062', 'Adipocytes (Minor salivary gland)': '0.154', 'Somatotropes': '-0.173', 'Lactotropes': '-0.241', 'Gonadotropes': '-0.071', 'Corticotropes': '-0.216', 'Thyrotropes': '-0.096', 'Undifferentiated cells (Pituitary gland)': '0.391', 'Mitotic cells (Spleen)': '0.059', 'Platelets': '0.144', 'Erythrocytes': '-0.117', 'Hematopoietic stem cells': '0.039', 'B-cells (Spleen)': '0.510', 'NK-cells (Spleen)': '-0.017', 'Amygdala excitatory': '0.3', 'Cerebellar inhibitory': '0.1', 'Cge interneuron': '0.4', 'Deep-layer corticothalamic and 6b': '0.1', 'Deep-layer intratelencephalic': '0.2', 'Deep-layer near-projecting': '0.3', 'Eccentric medium spiny neuron': '0.4', 'Hippocampal ca1-3': '0.5', 'Hippocampal ca4': '0.1', 'Hippocampal dentate gyrus': '0.1', 'Lamp5-lhx6 and chandelier': '0.6', 'Lower rhombic lip': '0.1', 'Mammillary body': '0.2', 'Medium spiny neuron': '0.4', 'Mge interneuron': '0.3', 'Midbrain-derived inhibitory': '0.2', 'Miscellaneous': '0.2', 'Splatter': '0.3', 'Thalamic excitatory': '0.3', 'Upper rhombic lip': '0.9', 'Upper-layer intratelencephalic': '0.3', 'Astrocyte': '0.7', 'Bergmann glia': '0.4', 'Central nervous system macrophage': '0.9', 'Choroid plexus epithelial cell': '0.0', 'Committed oligodendrocyte precursor': '0.2', 'Ependymal cell': '0.1', 'Oligodendrocyte': '0.3', 'Oligodendrocyte precursor cell': '0.3', 'Endothelial cell': '0.1', 'Pericyte': '0.6', 'Vascular associated smooth muscle cell': '0.4', 'Fibroblast': '0.3', 'Leukocyte': '0.4', 'Basophil': '4.3', 'Eosinophil': '0.0', 'Neutrophil': '12.4', 'Classical monocyte': '0.2', 'Non-classical monocyte': '0.1', 'Intermediate monocyte': '0.7', 'T-reg': '0.6', 'GdT-cell': '0.2', 'MAIT T-cell': '1.9', 'Memory CD4 T-cell': '0.9', 'Naive CD4 T-cell': '0.3', 'Memory CD8 T-cell': '0.6', 'Naive CD8 T-cell': '0.4', 'Memory B-cell': '23.6', 'Naive B-cell': '0.1', 'Plasmacytoid DC': '456.0', 'Myeloid DC': '1.1', 'NK-cell': '0.1', 'Total PBMC': '5.5', 'Vd2 gdTCR': '0.6', 'Memory CD4 T-cell Th1\\/Th17': '0.2', 'Memory CD4 T-cell Th17': '0.2', 'Memory CD4 T-cell Th2': '0.3', 'Non-Vd2 gdTCR': '0.5', 'Memory CD4 T-cell Th1': '0.3', 'Memory CD4 T-cell TFH': '0.3', 'Terminal effector memory CD4 T-cell': '1.9', 'Central memory CD8 T-cell': '1.1', 'Effector memory CD8 T-cell': '0.1', 'Terminal effector memory CD8 T-cell': '0.1', 'Non-switched memory B-cell': '68.6', 'Plasmablast': '23.6', 'Switched memory B-cell': '45.3', 'Exhausted memory B-cell': '46.5', 'Progenitor cell': '3.4', 'Memory T-reg': '0.3', 'Naive CD4 T-cell activated': '0.1', 'Naive CD8 T-cell activated': '0.1', 'Naive T-reg': '0.3'}
8AR3
{'Adipose Tissue': 1.4036666528239203, 'Adrenal Gland': 0.5379480620155039, 'Bladder': 2.0188523809523806, 'Blood': 11.078379773950484, 'Blood Vessel': 2.045118501872659, 'Brain': 1.6826528425435276, 'Breast': 1.1921779956427014, 'Cervix Uteri': 3.774784210526316, 'Colon': 1.9339365853658537, 'Esophagus': 1.4013961660899654, 'Fallopian Tube': 2.7071555555555555, 'Heart': 0.46085, 'Kidney': 0.6571056179775281, 'Liver': 0.3677314159292035, 'Lung': 1.7192410034602077, 'Muscle': 1.6459444707347448, 'Nerve': 2.427732633279483, 'Ovary': 4.217165, 'Pancreas': 0.1862323780487804, 'Pituitary': 1.0853265017667846, 'Prostate': 2.0451526530612245, 'Salivary Gland': 1.022793209876543, 'Skin': 0.6458710497512438, 'Small Intestine': 6.100227272727273, 'Spleen': 8.518240663900416, 'Stomach': 0.8774933147632312, 'Testis': 1.5356736842105263, 'Thyroid': 1.930964318529862, 'Uterus': 3.011875352112676, 'Vagina': 2.4533397435897437}
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ZnF_A20
component of a ubiquitin-editing protein complex, comprising also RNF11, ITCH and TAX1BP1
null
null
IKBKG, ITCH, YWHAH, TRAF6, RIPK1, TRAF2, TNIP1, TAX1BP1, RNF11, YWHAZ
UBE2N, UBE2D3, RIPK1
11, 48, 63
null
UBE2N, UBE2D3
Homodimer
null
74.507911
0.508165
87.039147
0.338808
486