E3_UniProtID string | Sub_UniProtID string | Reference string | Source string | E3_Gene_Name string | E3_Sequence string | E3_Species string | E3_Subcellular_Location string | E3_HPA_Expression string | E3_scRNA_Data string | E3_PDB_IDs string | E3_GTEx_expression string | Sub_Gene_Name string | Sub_Sequence string | Sub_Species string | Sub_Subcellular_Location string | Sub_HPA_Expression string | Sub_scRNA_Data string | Sub_PDB_IDs string | Sub_GTEx_expression string | E3_Confidence_Scores string | E3_Relative_SASA string | Sub_Confidence_Scores string | Sub_Relative_SASA string | E3_Type string | E3_Complex string | Complex_name string | Susbtrate_specificity string | E3_Known_direct_interactions string | E3_Substrates string | PolyUb_Lys string | C/N_end string | Associated_E2 string | Self_oligomerization string | Atypical_AA_ubi string | E3_Confidence_Scores_Avg float64 | E3_Relative_SASA_Avg float64 | Sub_Confidence_Scores_Avg float64 | Sub_Relative_SASA_Avg float64 | ClusterID int64 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
P12830 | P78396 | null | degron_data | CDH1 | MGPWSRSLSALLLLLQVSSWLCQEPEPCHPGFDAESYTFTVPRRHLERGRVLGRVNFEDCTGRQRTAYFSLDTRFKVGTDGVITVKRPLRFHNPQIHFLVYAWDSTYRKFSTKVTLNTVGHHHRPPPHQASVSGIQAELLTFPNSSPGLRRQKRDWVIPPISCPENEKGPFPKNLVQIKSNKDKEGKVFYSITGQGADTPPVGVFIIERETGWLKVTEPLDRERIATYTLFSHAVSSNGNAVEDPMEILITVTDQNDNKPEFTQEVFKGSVMEGALPGTSVMEVTATDADDDVNTYNAAIAYTILSQDPELPDKNMFTINRNTGVISVVTTGLDRESFPTYTLVVQAADLQGEGLSTTATAVITVTDTNDNPPIFNPTTYKGQVPENEANVVITTLKVTDADAPNTPAWEAVYTILNDDGGQFVVTTNPVNNDGILKTAKGLDFEAKQQYILHVAVTNVVPFEVSLTTSTATVTVDVLDVNEAPIFVPPEKRVEVSEDFGVGQEITSYTAQEPDTFMEQKITYRIWRDTANWLEINPDTGAISTRAELDREDFEHVKNSTYTALIIATDNGSPVATGTGTLLLILSDVNDNAPIPEPRTIFFCERNPKPQVINIIDADLPPNTSPFTAELTHGASANWTIQYNDPTQESIILKPKMALEVGDYKINLKLMDNQNKDQVTTLEVSVCDCEGAAGVCRKAQPVEAGLQIPAILGILGGILALLILILLLLLFLRRRAVVKEPLLPPEDDTRDNVYYYDEEGGGEEDQDFDLSQLHRGLDARPEVTRNDVAPTLMSVPRYLPRPANPDEIGNFIDENLKAADTDPTAPPYDSLLVFDYEGSGSEAASLSSLNSSESDKDQDYDYLNEWGNRFKKLADMYGGGEDD | Homo sapiens | Cell junction, adherens junction, Cell membrane, Endosome, Golgi apparatus, trans-Golgi network, Cytoplasm, Cell junction, desmosome | Tissue enhanced (parathyroid) | {'Ciliated cells': '119.1', 'Basal respiratory cells': '71.1', 'Club cells': '97.3', 'Ionocytes': '81.0', 'Mucus glandular cells': '155.0', 'Serous glandular cells': '67.8', 'Gastric mucus-secreting cells': '133.2', 'Proximal enterocytes': '140.9', 'Paneth cells': '125.1', 'Distal enterocytes': '307.5', 'Intestinal goblet cells': '173.5', 'Exocrine glandular cells': '-0.605', 'Basal prostatic cells': '68.3', 'Prostatic glandular cells': '186.7', 'Breast glandular cells': '0.773', 'Breast myoepithelial cells': '0.700', 'Glandular and luminal cells': '313.0', 'Secretory cells': '82.3', 'Basal keratinocytes': '102.5', 'Suprabasal keratinocytes': '162.6', 'Basal squamous epithelial cells': '51.0', 'Squamous epithelial cells': '106.9', 'Alveolar cells type 1': '0.437', 'Alveolar cells type 2': '0.706', 'Salivary duct cells': '95.9', 'Ductal cells': '0.541', 'Hepatocytes': '0.600', 'Cholangiocytes': '129.7', 'Proximal tubular cells': '0.042', 'Distal tubular cells': '0.0', 'Collecting duct cells': '143.9', 'Mesothelial cells': '0.799', 'Sertoli cells': '0.252', 'Granulosa cells': '12.9', 'Enteroendocrine cells': '92.4', 'Pancreatic endocrine cells': '78.1', 'Leydig cells': '0.264', 'Excitatory neurons': '0.7', 'Inhibitory neurons': '1.3', 'Cone photoreceptor cells': '0.0', 'Rod photoreceptor cells': '0.0', 'Bipolar cells': '0.2', 'Horizontal cells': '0.6', 'Astrocytes': '0.6', 'Oligodendrocyte precursor cells': '0.5', 'Oligodendrocytes': '29.9', 'Microglial cells': '0.9', 'Muller glia cells': '0.1', 'Schwann cells': '0.131', 'Spermatogonia': '0.392', 'Spermatocytes': '0.193', 'Early spermatids': '-0.217', 'Late spermatids': '-0.290', 'Oocytes': '16.9', 'Cytotrophoblasts': '119.2', 'Syncytiotrophoblasts': '45.0', 'Extravillous trophoblasts': '24.9', 'Endothelial cells': '6.1', 'Lymphatic endothelial cells': '0.4', 'Cardiomyocytes': '0.135', 'Skeletal myocytes': '0.107', 'Smooth muscle cells': '5.8', 'Adipocytes': '2.1', 'Melanocytes': '0.335', 'Fibroblasts': '6.5', 'Peritubular cells': '0.210', 'Endometrial stromal cells': '27.7', 'Ovarian stromal cells': '0.7', 'Undifferentiated cells': '101.6', 'T-cells': '2.9', 'B-cells': '4.4', 'Plasma cells': '6.1', 'Nk-cells': '0.0', 'Granulocytes': '8.4', 'Monocytes': '0.0', 'Macrophages': '6.0', 'Hofbauer cells': '4.3', 'Kupffer cells': '1.0', 'Dendritic cells': '5.9', 'Langerhans cells': '0.304', 'Erythroid cells': '0.036', 'Adipocytes (Subcutaneous)': '-0.081', 'Adipocytes (Visceral)': '-0.209', 'Breast glandular cells (progenitors)': '0.538', 'Adipocytes (Breast)': '-0.689', 'Colon enterocytes': '0.790', 'Colon enteroendocrine cells': '0.112', 'Enteric glia cells': '-0.048', 'Mitotic cells (Colon)': '0.299', 'Mitotic cells (Heart)': '0.120', 'Podocytes': '-0.118', 'Ascending Loop of Henle cells': '0.475', 'Intercalated cells': '0.212', 'Cholangiocyte': '0.090', 'NK-cells (Liver)': '-0.005', 'Respiratory ciliated cells': '-0.012', 'Mitotic cells (Lung)': '0.071', 'NK-cells (Lung)': '-0.266', 'B-cells (Lung)': '-0.296', 'Alpha cells': '0.270', 'Beta cells': '0.152', 'Prostate glandular cells': '0.764', 'Prostate basal glandular cells': '0.540', 'Urothelial cells': '0.205', 'Keratinocyte (other)': '0.510', 'Keratinocyte (granular)': '0.055', 'Hair cortex cells': '0.080', 'Inner root sheath cells': '0.131', 'Outer root sheath cells': '0.175', 'Sebaceous gland cells': '0.156', 'Eccrine sweat gland cells': '-0.207', 'Adipocytes (Skin)': '-0.244', 'Mitotic cells (Skin)': '0.442', 'Parietal cells': '0.654', 'Chief cells': '0.649', 'Gastric mucous cells': '0.781', 'Gastric enteroendocrine cells': '0.590', 'Mitotic cells (Stomach)': '0.445', 'Parafollicular cells': '0.173', 'Thyroid glandular cells': '0.865', 'Mitotic cells (Thyroid)': '-0.081', 'Adrenal cortex cells': '0.051', 'Adrenal medulla cells': '0.087', 'Mitotic cells (Adrenal gland)': '0.072', 'Minor salivary glandular cells': '0.371', 'Minor salivary gland ductal cells': '-0.142', 'Minor salivary gland basal cells': '0.582', 'Mitotic cells (Minor salivary gland)': '0.567', 'Adipocytes (Minor salivary gland)': '0.050', 'Somatotropes': '0.121', 'Lactotropes': '0.322', 'Gonadotropes': '0.330', 'Corticotropes': '0.180', 'Thyrotropes': '0.496', 'Undifferentiated cells (Pituitary gland)': '-0.108', 'Mitotic cells (Spleen)': '-0.228', 'Platelets': '-0.050', 'Erythrocytes': '-0.158', 'Hematopoietic stem cells': '-0.211', 'B-cells (Spleen)': '0.266', 'NK-cells (Spleen)': '0.309', 'Amygdala excitatory': '1.0', 'Cerebellar inhibitory': '0.9', 'Cge interneuron': '0.7', 'Deep-layer corticothalamic and 6b': '1.5', 'Deep-layer intratelencephalic': '0.7', 'Deep-layer near-projecting': '0.7', 'Eccentric medium spiny neuron': '0.6', 'Hippocampal ca1-3': '1.9', 'Hippocampal ca4': '1.2', 'Hippocampal dentate gyrus': '1.1', 'Lamp5-lhx6 and chandelier': '0.5', 'Lower rhombic lip': '0.8', 'Mammillary body': '0.6', 'Medium spiny neuron': '0.7', 'Mge interneuron': '1.7', 'Midbrain-derived inhibitory': '0.7', 'Miscellaneous': '0.9', 'Splatter': '3.8', 'Thalamic excitatory': '0.5', 'Upper rhombic lip': '0.8', 'Upper-layer intratelencephalic': '0.6', 'Astrocyte': '4.4', 'Bergmann glia': '0.2', 'Central nervous system macrophage': '0.6', 'Choroid plexus epithelial cell': '52.1', 'Committed oligodendrocyte precursor': '41.5', 'Ependymal cell': '4.8', 'Oligodendrocyte': '53.1', 'Oligodendrocyte precursor cell': '2.4', 'Endothelial cell': '0.7', 'Pericyte': '0.3', 'Vascular associated smooth muscle cell': '0.0', 'Fibroblast': '17.4', 'Leukocyte': '1.1', 'Basophil': '0.0', 'Eosinophil': '0.0', 'Neutrophil': '0.0', 'Classical monocyte': '0.0', 'Non-classical monocyte': '0.0', 'Intermediate monocyte': '0.0', 'T-reg': '2.3', 'GdT-cell': '0.0', 'MAIT T-cell': '0.0', 'Memory CD4 T-cell': '0.0', 'Naive CD4 T-cell': '0.1', 'Memory CD8 T-cell': '0.2', 'Naive CD8 T-cell': '0.3', 'Memory B-cell': '0.0', 'Naive B-cell': '0.1', 'Plasmacytoid DC': '46.6', 'Myeloid DC': '8.5', 'NK-cell': '0.1', 'Total PBMC': '0.7', 'Vd2 gdTCR': '0.0', 'Memory CD4 T-cell Th1\\/Th17': '0.1', 'Memory CD4 T-cell Th17': '0.2', 'Memory CD4 T-cell Th2': '2.9', 'Non-Vd2 gdTCR': '0.1', 'Memory CD4 T-cell Th1': '0.3', 'Memory CD4 T-cell TFH': '0.5', 'Terminal effector memory CD4 T-cell': '0.0', 'Central memory CD8 T-cell': '4.8', 'Effector memory CD8 T-cell': '0.0', 'Terminal effector memory CD8 T-cell': '0.6', 'Non-switched memory B-cell': '0.0', 'Plasmablast': '3.3', 'Switched memory B-cell': '0.0', 'Exhausted memory B-cell': '0.7', 'Progenitor cell': '2.3', 'Memory T-reg': '1.3', 'Naive CD4 T-cell activated': '0.3', 'Naive CD8 T-cell activated': '0.6', 'Naive T-reg': '0.1'} | 1O6S, 2O72, 2OMT, 2OMU, 2OMV, 2OMX, 2OMY, 2OMZ, 3FF7, 3FF8, 3L6X, 3L6Y, 4ZT1, 4ZTE, 6CXY, 6OLE, 6OLF, 6OLG, 6VEL, 7STZ, 8H62 | {'Adipose Tissue': 1.2125261088039867, 'Adrenal Gland': 0.1914223992248062, 'Bladder': 39.2033519047619, 'Blood': 1.340954264800861, 'Blood Vessel': 0.3121561692883895, 'Brain': 0.8550442199091597, 'Breast': 38.54918344226579, 'Cervix Uteri': 23.539115789473684, 'Colon': 43.41292142490372, 'Esophagus': 53.97513367404844, 'Fallopian Tube': 14.900277777777776, 'Heart': 0.119140469221835, 'Kidney': 25.040449438202245, 'Liver': 26.60802654867257, 'Lung': 35.447986366782004, 'Muscle': 0.1378936151930261, 'Nerve': 17.518468982229404, 'Ovary': 3.6515122222222223, 'Pancreas': 56.89676829268293, 'Pituitary': 24.68741660777385, 'Prostate': 61.279967346938776, 'Salivary Gland': 92.01685185185184, 'Skin': 79.77571720232172, 'Small Intestine': 71.7519320855615, 'Spleen': 10.061029045643156, 'Stomach': 58.07813805013927, 'Testis': 0.8144204986149585, 'Thyroid': 135.176797856049, 'Uterus': 1.442593943661972, 'Vagina': 86.52345512820513} | CCNA1 | METGFPAIMYPGSFIGGWGEEYLSWEGPGLPDFVFQQQPVESEAMHCSNPKSGVVLATVARGPDACQILTRAPLGQDPPQRTVLGLLTANGQYRRTCGQGITRIRCYSGSENAFPPAGKKALPDCGVQEPPKQGFDIYMDELEQGDRDSCSVREGMAFEDVYEVDTGTLKSDLHFLLDFNTVSPMLVDSSLLSQSEDISSLGTDVINVTEYAEEIYQYLREAEIRHRPKAHYMKKQPDITEGMRTILVDWLVEVGEEYKLRAETLYLAVNFLDRFLSCMSVLRGKLQLVGTAAMLLASKYEEIYPPEVDEFVYITDDTYTKRQLLKMEHLLLKVLAFDLTVPTTNQFLLQYLRRQGVCVRTENLAKYVAELSLLEADPFLKYLPSLIAAAAFCLANYTVNKHFWPETLAAFTGYSLSEIVPCLSELHKAYLDIPHRPQQAIREKYKASKYLCVSLMEPPAVLLLQ | Homo sapiens | Nucleus | Tissue enhanced (parathyroid gland, testis) | {'Ciliated cells': '63.2', 'Basal respiratory cells': '18.7', 'Club cells': '5.9', 'Ionocytes': '12.9', 'Mucus glandular cells': '0.1', 'Serous glandular cells': '0.1', 'Gastric mucus-secreting cells': '0.0', 'Proximal enterocytes': '0.0', 'Paneth cells': '0.0', 'Distal enterocytes': '0.0', 'Intestinal goblet cells': '0.0', 'Exocrine glandular cells': '-0.292', 'Basal prostatic cells': '0.2', 'Prostatic glandular cells': '0.0', 'Breast glandular cells': '0.509', 'Breast myoepithelial cells': '0.452', 'Glandular and luminal cells': '27.7', 'Secretory cells': '36.6', 'Basal keratinocytes': '0.7', 'Suprabasal keratinocytes': '0.2', 'Basal squamous epithelial cells': '0.0', 'Squamous epithelial cells': '0.2', 'Alveolar cells type 1': '-0.056', 'Alveolar cells type 2': '0.039', 'Salivary duct cells': '0.3', 'Ductal cells': '0.360', 'Hepatocytes': '0.004', 'Cholangiocytes': '0.0', 'Proximal tubular cells': '0.204', 'Distal tubular cells': '0.0', 'Collecting duct cells': '0.0', 'Mesothelial cells': '0.084', 'Sertoli cells': '-0.504', 'Granulosa cells': '0.8', 'Enteroendocrine cells': '0.0', 'Pancreatic endocrine cells': '0.0', 'Leydig cells': '-0.521', 'Excitatory neurons': '3.4', 'Inhibitory neurons': '2.8', 'Cone photoreceptor cells': '0.0', 'Rod photoreceptor cells': '0.3', 'Bipolar cells': '0.4', 'Horizontal cells': '1.9', 'Astrocytes': '0.3', 'Oligodendrocyte precursor cells': '0.5', 'Oligodendrocytes': '0.4', 'Microglial cells': '0.0', 'Muller glia cells': '1.4', 'Schwann cells': '0.334', 'Spermatogonia': '-0.286', 'Spermatocytes': '0.177', 'Early spermatids': '0.921', 'Late spermatids': '0.574', 'Oocytes': '0.0', 'Cytotrophoblasts': '0.0', 'Syncytiotrophoblasts': '0.2', 'Extravillous trophoblasts': '0.9', 'Endothelial cells': '0.3', 'Lymphatic endothelial cells': '0.8', 'Cardiomyocytes': '0.221', 'Skeletal myocytes': '-0.194', 'Smooth muscle cells': '0.6', 'Adipocytes': '0.1', 'Melanocytes': '0.056', 'Fibroblasts': '0.9', 'Peritubular cells': '-0.406', 'Endometrial stromal cells': '1.6', 'Ovarian stromal cells': '0.1', 'Undifferentiated cells': '0.0', 'T-cells': '0.3', 'B-cells': '0.1', 'Plasma cells': '0.1', 'Nk-cells': '0.0', 'Granulocytes': '16.8', 'Monocytes': '0.0', 'Macrophages': '0.9', 'Hofbauer cells': '0.1', 'Kupffer cells': '0.0', 'Dendritic cells': '1.2', 'Langerhans cells': '-0.154', 'Erythroid cells': '0.132', 'Adipocytes (Subcutaneous)': '-0.271', 'Adipocytes (Visceral)': '-0.164', 'Breast glandular cells (progenitors)': '0.520', 'Adipocytes (Breast)': '-0.402', 'Colon enterocytes': '-0.027', 'Colon enteroendocrine cells': '0.696', 'Enteric glia cells': '0.286', 'Mitotic cells (Colon)': '-0.036', 'Mitotic cells (Heart)': '0.414', 'Podocytes': '0.044', 'Ascending Loop of Henle cells': '0.154', 'Intercalated cells': '0.003', 'Cholangiocyte': '0.144', 'NK-cells (Liver)': '-0.019', 'Respiratory ciliated cells': '0.771', 'Mitotic cells (Lung)': '0.110', 'NK-cells (Lung)': '0.008', 'B-cells (Lung)': '0.039', 'Alpha cells': '0.234', 'Beta cells': '0.096', 'Prostate glandular cells': '-0.161', 'Prostate basal glandular cells': '-0.003', 'Urothelial cells': '-0.083', 'Keratinocyte (other)': '-0.472', 'Keratinocyte (granular)': '-0.322', 'Hair cortex cells': '0.669', 'Inner root sheath cells': '0.709', 'Outer root sheath cells': '0.611', 'Sebaceous gland cells': '0.139', 'Eccrine sweat gland cells': '0.397', 'Adipocytes (Skin)': '0.376', 'Mitotic cells (Skin)': '0.180', 'Parietal cells': '-0.579', 'Chief cells': '-0.471', 'Gastric mucous cells': '-0.379', 'Gastric enteroendocrine cells': '-0.339', 'Mitotic cells (Stomach)': '-0.042', 'Parafollicular cells': '0.100', 'Thyroid glandular cells': '-0.037', 'Mitotic cells (Thyroid)': '0.161', 'Adrenal cortex cells': '0.040', 'Adrenal medulla cells': '0.254', 'Mitotic cells (Adrenal gland)': '0.118', 'Minor salivary glandular cells': '0.629', 'Minor salivary gland ductal cells': '0.191', 'Minor salivary gland basal cells': '0.136', 'Mitotic cells (Minor salivary gland)': '0.296', 'Adipocytes (Minor salivary gland)': '0.166', 'Somatotropes': '0.253', 'Lactotropes': '0.356', 'Gonadotropes': '-0.039', 'Corticotropes': '0.328', 'Thyrotropes': '0.309', 'Undifferentiated cells (Pituitary gland)': '-0.359', 'Mitotic cells (Spleen)': '0.068', 'Platelets': '0.156', 'Erythrocytes': '0.057', 'Hematopoietic stem cells': '0.209', 'B-cells (Spleen)': '-0.101', 'NK-cells (Spleen)': '-0.078', 'Amygdala excitatory': '5.8', 'Cerebellar inhibitory': '2.8', 'Cge interneuron': '5.1', 'Deep-layer corticothalamic and 6b': '8.2', 'Deep-layer intratelencephalic': '4.0', 'Deep-layer near-projecting': '5.7', 'Eccentric medium spiny neuron': '11.1', 'Hippocampal ca1-3': '7.5', 'Hippocampal ca4': '5.6', 'Hippocampal dentate gyrus': '6.2', 'Lamp5-lhx6 and chandelier': '6.6', 'Lower rhombic lip': '5.6', 'Mammillary body': '3.9', 'Medium spiny neuron': '9.4', 'Mge interneuron': '3.7', 'Midbrain-derived inhibitory': '5.1', 'Miscellaneous': '8.1', 'Splatter': '7.1', 'Thalamic excitatory': '3.5', 'Upper rhombic lip': '1.3', 'Upper-layer intratelencephalic': '5.7', 'Astrocyte': '0.4', 'Bergmann glia': '0.7', 'Central nervous system macrophage': '0.4', 'Choroid plexus epithelial cell': '2.1', 'Committed oligodendrocyte precursor': '0.8', 'Ependymal cell': '25.9', 'Oligodendrocyte': '0.3', 'Oligodendrocyte precursor cell': '0.4', 'Endothelial cell': '0.4', 'Pericyte': '0.7', 'Vascular associated smooth muscle cell': '1.1', 'Fibroblast': '0.3', 'Leukocyte': '0.1', 'Basophil': '226.3', 'Eosinophil': '0.4', 'Neutrophil': '0.3', 'Classical monocyte': '0.0', 'Non-classical monocyte': '0.0', 'Intermediate monocyte': '0.0', 'T-reg': '0.1', 'GdT-cell': '0.0', 'MAIT T-cell': '0.2', 'Memory CD4 T-cell': '0.0', 'Naive CD4 T-cell': '0.0', 'Memory CD8 T-cell': '0.0', 'Naive CD8 T-cell': '0.0', 'Memory B-cell': '0.0', 'Naive B-cell': '0.4', 'Plasmacytoid DC': '0.0', 'Myeloid DC': '0.0', 'NK-cell': '0.0', 'Total PBMC': '2.2', 'Vd2 gdTCR': '0.0', 'Memory CD4 T-cell Th1\\/Th17': '0.0', 'Memory CD4 T-cell Th17': '0.0', 'Memory CD4 T-cell Th2': '0.0', 'Non-Vd2 gdTCR': '0.0', 'Memory CD4 T-cell Th1': '0.0', 'Memory CD4 T-cell TFH': '0.0', 'Terminal effector memory CD4 T-cell': '0.0', 'Central memory CD8 T-cell': '0.0', 'Effector memory CD8 T-cell': '0.0', 'Terminal effector memory CD8 T-cell': '0.0', 'Non-switched memory B-cell': '0.4', 'Plasmablast': '1.3', 'Switched memory B-cell': '0.2', 'Exhausted memory B-cell': '1.6', 'Progenitor cell': '1.4', 'Memory T-reg': '0.0', 'Naive CD4 T-cell activated': '0.0', 'Naive CD8 T-cell activated': '0.1', 'Naive T-reg': '0.0'} | null | {'Adipose Tissue': 0.4920498006644518, 'Adrenal Gland': 0.6211815891472868, 'Bladder': 0.3310395238095238, 'Blood': 4.274904499461787, 'Blood Vessel': 0.6093116404494382, 'Brain': 5.7298269909159725, 'Breast': 0.9459007625272332, 'Cervix Uteri': 4.544005263157895, 'Colon': 0.7117023491655968, 'Esophagus': 0.4226844498269896, 'Fallopian Tube': 13.536555555555555, 'Heart': 0.1997436852497096, 'Kidney': 0.4816573033707865, 'Liver': 0.0884278938053097, 'Lung': 2.2177321280276816, 'Muscle': 0.9621126351183064, 'Nerve': 2.0081823909531504, 'Ovary': 0.8736613888888889, 'Pancreas': 0.0492470579268292, 'Pituitary': 12.370113427561837, 'Prostate': 0.7757826530612245, 'Salivary Gland': 0.8150720987654322, 'Skin': 0.3888909784411277, 'Small Intestine': 0.4413763101604278, 'Spleen': 0.875930580912863, 'Stomach': 0.4098062674094708, 'Testis': 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0.5, 0.0, 0.27, 0.48, 0.0, 0.0, 0.33, 0.26, 0.02, 0.09, 0.49, 0.06, 0.03, 0.36, 0.45, 0.04, 0.57, 0.85, 0.28, 0.71, 0.13, 0.21, 0.11, 0.01, 0.26, 0.55, 0.11, 0.03, 0.4, 0.32, 0.73, 0.69, 0.23, 0.49, 0.34, 0.0, 0.08, 0.56, 0.28, 0.88, 0.3, 0.13, 0.79, 0.74, 0.13, 0.6, 0.38, 0.91] | null | Component of an E-cadherin/ catenin adhesion complex composed of at least E-cadherin/CDH1, beta-catenin/CTNNB1 or gamma-catenin/JUP, and potentially alpha-catenin/CTNNA1. Forms a ternary complex composed of ADAM10, CADH1 and EPHA4, | null | null | KLRG1, SPEF1, DLGAP5, AJAP1, RAPGEF2, RAB8B, PIP5K1C, PKP2, TRPV4, CTNNB1, CAV1, DDR1, TBC1D2, CTNNA1, JUP, CTNND1, PSEN1, LIMA1, CDH1, JUP, ADAM10, CADH1 , EPHA4, | null | null | null | null | Homodimer | null | 79.91949 | 0.474025 | 67.89957 | 0.547548 | 1,709 |
P12830 | Q02363 | null | degron_data | CDH1 | MGPWSRSLSALLLLLQVSSWLCQEPEPCHPGFDAESYTFTVPRRHLERGRVLGRVNFEDCTGRQRTAYFSLDTRFKVGTDGVITVKRPLRFHNPQIHFLVYAWDSTYRKFSTKVTLNTVGHHHRPPPHQASVSGIQAELLTFPNSSPGLRRQKRDWVIPPISCPENEKGPFPKNLVQIKSNKDKEGKVFYSITGQGADTPPVGVFIIERETGWLKVTEPLDRERIATYTLFSHAVSSNGNAVEDPMEILITVTDQNDNKPEFTQEVFKGSVMEGALPGTSVMEVTATDADDDVNTYNAAIAYTILSQDPELPDKNMFTINRNTGVISVVTTGLDRESFPTYTLVVQAADLQGEGLSTTATAVITVTDTNDNPPIFNPTTYKGQVPENEANVVITTLKVTDADAPNTPAWEAVYTILNDDGGQFVVTTNPVNNDGILKTAKGLDFEAKQQYILHVAVTNVVPFEVSLTTSTATVTVDVLDVNEAPIFVPPEKRVEVSEDFGVGQEITSYTAQEPDTFMEQKITYRIWRDTANWLEINPDTGAISTRAELDREDFEHVKNSTYTALIIATDNGSPVATGTGTLLLILSDVNDNAPIPEPRTIFFCERNPKPQVINIIDADLPPNTSPFTAELTHGASANWTIQYNDPTQESIILKPKMALEVGDYKINLKLMDNQNKDQVTTLEVSVCDCEGAAGVCRKAQPVEAGLQIPAILGILGGILALLILILLLLLFLRRRAVVKEPLLPPEDDTRDNVYYYDEEGGGEEDQDFDLSQLHRGLDARPEVTRNDVAPTLMSVPRYLPRPANPDEIGNFIDENLKAADTDPTAPPYDSLLVFDYEGSGSEAASLSSLNSSESDKDQDYDYLNEWGNRFKKLADMYGGGEDD | Homo sapiens | Cell junction, adherens junction, Cell membrane, Endosome, Golgi apparatus, trans-Golgi network, Cytoplasm, Cell junction, desmosome | Tissue enhanced (parathyroid) | {'Ciliated cells': '119.1', 'Basal respiratory cells': '71.1', 'Club cells': '97.3', 'Ionocytes': '81.0', 'Mucus glandular cells': '155.0', 'Serous glandular cells': '67.8', 'Gastric mucus-secreting cells': '133.2', 'Proximal enterocytes': '140.9', 'Paneth cells': '125.1', 'Distal enterocytes': '307.5', 'Intestinal goblet cells': '173.5', 'Exocrine glandular cells': '-0.605', 'Basal prostatic cells': '68.3', 'Prostatic glandular cells': '186.7', 'Breast glandular cells': '0.773', 'Breast myoepithelial cells': '0.700', 'Glandular and luminal cells': '313.0', 'Secretory cells': '82.3', 'Basal keratinocytes': '102.5', 'Suprabasal keratinocytes': '162.6', 'Basal squamous epithelial cells': '51.0', 'Squamous epithelial cells': '106.9', 'Alveolar cells type 1': '0.437', 'Alveolar cells type 2': '0.706', 'Salivary duct cells': '95.9', 'Ductal cells': '0.541', 'Hepatocytes': '0.600', 'Cholangiocytes': '129.7', 'Proximal tubular cells': '0.042', 'Distal tubular cells': '0.0', 'Collecting duct cells': '143.9', 'Mesothelial cells': '0.799', 'Sertoli cells': '0.252', 'Granulosa cells': '12.9', 'Enteroendocrine cells': '92.4', 'Pancreatic endocrine cells': '78.1', 'Leydig cells': '0.264', 'Excitatory neurons': '0.7', 'Inhibitory neurons': '1.3', 'Cone photoreceptor cells': '0.0', 'Rod photoreceptor cells': '0.0', 'Bipolar cells': '0.2', 'Horizontal cells': '0.6', 'Astrocytes': '0.6', 'Oligodendrocyte precursor cells': '0.5', 'Oligodendrocytes': '29.9', 'Microglial cells': '0.9', 'Muller glia cells': '0.1', 'Schwann cells': '0.131', 'Spermatogonia': '0.392', 'Spermatocytes': '0.193', 'Early spermatids': '-0.217', 'Late spermatids': '-0.290', 'Oocytes': '16.9', 'Cytotrophoblasts': '119.2', 'Syncytiotrophoblasts': '45.0', 'Extravillous trophoblasts': '24.9', 'Endothelial cells': '6.1', 'Lymphatic endothelial cells': '0.4', 'Cardiomyocytes': '0.135', 'Skeletal myocytes': '0.107', 'Smooth muscle cells': '5.8', 'Adipocytes': '2.1', 'Melanocytes': '0.335', 'Fibroblasts': '6.5', 'Peritubular cells': '0.210', 'Endometrial stromal cells': '27.7', 'Ovarian stromal cells': '0.7', 'Undifferentiated cells': '101.6', 'T-cells': '2.9', 'B-cells': '4.4', 'Plasma cells': '6.1', 'Nk-cells': '0.0', 'Granulocytes': '8.4', 'Monocytes': '0.0', 'Macrophages': '6.0', 'Hofbauer cells': '4.3', 'Kupffer cells': '1.0', 'Dendritic cells': '5.9', 'Langerhans cells': '0.304', 'Erythroid cells': '0.036', 'Adipocytes (Subcutaneous)': '-0.081', 'Adipocytes (Visceral)': '-0.209', 'Breast glandular cells (progenitors)': '0.538', 'Adipocytes (Breast)': '-0.689', 'Colon enterocytes': '0.790', 'Colon enteroendocrine cells': '0.112', 'Enteric glia cells': '-0.048', 'Mitotic cells (Colon)': '0.299', 'Mitotic cells (Heart)': '0.120', 'Podocytes': '-0.118', 'Ascending Loop of Henle cells': '0.475', 'Intercalated cells': '0.212', 'Cholangiocyte': '0.090', 'NK-cells (Liver)': '-0.005', 'Respiratory ciliated cells': '-0.012', 'Mitotic cells (Lung)': '0.071', 'NK-cells (Lung)': '-0.266', 'B-cells (Lung)': '-0.296', 'Alpha cells': '0.270', 'Beta cells': '0.152', 'Prostate glandular cells': '0.764', 'Prostate basal glandular cells': '0.540', 'Urothelial cells': '0.205', 'Keratinocyte (other)': '0.510', 'Keratinocyte (granular)': '0.055', 'Hair cortex cells': '0.080', 'Inner root sheath cells': '0.131', 'Outer root sheath cells': '0.175', 'Sebaceous gland cells': '0.156', 'Eccrine sweat gland cells': '-0.207', 'Adipocytes (Skin)': '-0.244', 'Mitotic cells (Skin)': '0.442', 'Parietal cells': '0.654', 'Chief cells': '0.649', 'Gastric mucous cells': '0.781', 'Gastric enteroendocrine cells': '0.590', 'Mitotic cells (Stomach)': '0.445', 'Parafollicular cells': '0.173', 'Thyroid glandular cells': '0.865', 'Mitotic cells (Thyroid)': '-0.081', 'Adrenal cortex cells': '0.051', 'Adrenal medulla cells': '0.087', 'Mitotic cells (Adrenal gland)': '0.072', 'Minor salivary glandular cells': '0.371', 'Minor salivary gland ductal cells': '-0.142', 'Minor salivary gland basal cells': '0.582', 'Mitotic cells (Minor salivary gland)': '0.567', 'Adipocytes (Minor salivary gland)': '0.050', 'Somatotropes': '0.121', 'Lactotropes': '0.322', 'Gonadotropes': '0.330', 'Corticotropes': '0.180', 'Thyrotropes': '0.496', 'Undifferentiated cells (Pituitary gland)': '-0.108', 'Mitotic cells (Spleen)': '-0.228', 'Platelets': '-0.050', 'Erythrocytes': '-0.158', 'Hematopoietic stem cells': '-0.211', 'B-cells (Spleen)': '0.266', 'NK-cells (Spleen)': '0.309', 'Amygdala excitatory': '1.0', 'Cerebellar inhibitory': '0.9', 'Cge interneuron': '0.7', 'Deep-layer corticothalamic and 6b': '1.5', 'Deep-layer intratelencephalic': '0.7', 'Deep-layer near-projecting': '0.7', 'Eccentric medium spiny neuron': '0.6', 'Hippocampal ca1-3': '1.9', 'Hippocampal ca4': '1.2', 'Hippocampal dentate gyrus': '1.1', 'Lamp5-lhx6 and chandelier': '0.5', 'Lower rhombic lip': '0.8', 'Mammillary body': '0.6', 'Medium spiny neuron': '0.7', 'Mge interneuron': '1.7', 'Midbrain-derived inhibitory': '0.7', 'Miscellaneous': '0.9', 'Splatter': '3.8', 'Thalamic excitatory': '0.5', 'Upper rhombic lip': '0.8', 'Upper-layer intratelencephalic': '0.6', 'Astrocyte': '4.4', 'Bergmann glia': '0.2', 'Central nervous system macrophage': '0.6', 'Choroid plexus epithelial cell': '52.1', 'Committed oligodendrocyte precursor': '41.5', 'Ependymal cell': '4.8', 'Oligodendrocyte': '53.1', 'Oligodendrocyte precursor cell': '2.4', 'Endothelial cell': '0.7', 'Pericyte': '0.3', 'Vascular associated smooth muscle cell': '0.0', 'Fibroblast': '17.4', 'Leukocyte': '1.1', 'Basophil': '0.0', 'Eosinophil': '0.0', 'Neutrophil': '0.0', 'Classical monocyte': '0.0', 'Non-classical monocyte': '0.0', 'Intermediate monocyte': '0.0', 'T-reg': '2.3', 'GdT-cell': '0.0', 'MAIT T-cell': '0.0', 'Memory CD4 T-cell': '0.0', 'Naive CD4 T-cell': '0.1', 'Memory CD8 T-cell': '0.2', 'Naive CD8 T-cell': '0.3', 'Memory B-cell': '0.0', 'Naive B-cell': '0.1', 'Plasmacytoid DC': '46.6', 'Myeloid DC': '8.5', 'NK-cell': '0.1', 'Total PBMC': '0.7', 'Vd2 gdTCR': '0.0', 'Memory CD4 T-cell Th1\\/Th17': '0.1', 'Memory CD4 T-cell Th17': '0.2', 'Memory CD4 T-cell Th2': '2.9', 'Non-Vd2 gdTCR': '0.1', 'Memory CD4 T-cell Th1': '0.3', 'Memory CD4 T-cell TFH': '0.5', 'Terminal effector memory CD4 T-cell': '0.0', 'Central memory CD8 T-cell': '4.8', 'Effector memory CD8 T-cell': '0.0', 'Terminal effector memory CD8 T-cell': '0.6', 'Non-switched memory B-cell': '0.0', 'Plasmablast': '3.3', 'Switched memory B-cell': '0.0', 'Exhausted memory B-cell': '0.7', 'Progenitor cell': '2.3', 'Memory T-reg': '1.3', 'Naive CD4 T-cell activated': '0.3', 'Naive CD8 T-cell activated': '0.6', 'Naive T-reg': '0.1'} | 1O6S, 2O72, 2OMT, 2OMU, 2OMV, 2OMX, 2OMY, 2OMZ, 3FF7, 3FF8, 3L6X, 3L6Y, 4ZT1, 4ZTE, 6CXY, 6OLE, 6OLF, 6OLG, 6VEL, 7STZ, 8H62 | {'Adipose Tissue': 1.2125261088039867, 'Adrenal Gland': 0.1914223992248062, 'Bladder': 39.2033519047619, 'Blood': 1.340954264800861, 'Blood Vessel': 0.3121561692883895, 'Brain': 0.8550442199091597, 'Breast': 38.54918344226579, 'Cervix Uteri': 23.539115789473684, 'Colon': 43.41292142490372, 'Esophagus': 53.97513367404844, 'Fallopian Tube': 14.900277777777776, 'Heart': 0.119140469221835, 'Kidney': 25.040449438202245, 'Liver': 26.60802654867257, 'Lung': 35.447986366782004, 'Muscle': 0.1378936151930261, 'Nerve': 17.518468982229404, 'Ovary': 3.6515122222222223, 'Pancreas': 56.89676829268293, 'Pituitary': 24.68741660777385, 'Prostate': 61.279967346938776, 'Salivary Gland': 92.01685185185184, 'Skin': 79.77571720232172, 'Small Intestine': 71.7519320855615, 'Spleen': 10.061029045643156, 'Stomach': 58.07813805013927, 'Testis': 0.8144204986149585, 'Thyroid': 135.176797856049, 'Uterus': 1.442593943661972, 'Vagina': 86.52345512820513} | ID2 | MKAFSPVRSVRKNSLSDHSLGISRSKTPVDDPMSLLYNMNDCYSKLKELVPSIPQNKKVSKMEILQHVIDYILDLQIALDSHPTIVSLHHQRPGQNQASRTPLTTLNTDISILSLQASEFPSELMSNDSKALCG | Homo sapiens | Cytoplasm, Nucleus | Tissue enhanced (parathyroid) | {'Ciliated cells': '172.6', 'Basal respiratory cells': '470.7', 'Club cells': '132.4', 'Ionocytes': '363.0', 'Mucus glandular cells': '130.8', 'Serous glandular cells': '87.5', 'Gastric mucus-secreting cells': '188.7', 'Proximal enterocytes': '219.6', 'Paneth cells': '395.3', 'Distal enterocytes': '363.8', 'Intestinal goblet cells': '628.1', 'Exocrine glandular cells': '-0.560', 'Basal prostatic cells': '152.0', 'Prostatic glandular cells': '128.2', 'Breast glandular cells': '0.279', 'Breast myoepithelial cells': '0.364', 'Glandular and luminal cells': '641.5', 'Secretory cells': '45.8', 'Basal keratinocytes': '121.4', 'Suprabasal keratinocytes': '101.1', 'Basal squamous epithelial cells': '99.1', 'Squamous epithelial cells': '90.7', 'Alveolar cells type 1': '0.074', 'Alveolar cells type 2': '-0.181', 'Salivary duct cells': '120.4', 'Ductal cells': '0.543', 'Hepatocytes': '-0.081', 'Cholangiocytes': '270.9', 'Proximal tubular cells': '0.046', 'Distal tubular cells': '365.7', 'Collecting duct cells': '91.4', 'Mesothelial cells': '0.480', 'Sertoli cells': '0.354', 'Granulosa cells': '60.6', 'Enteroendocrine cells': '587.3', 'Pancreatic endocrine cells': '88.3', 'Leydig cells': '0.578', 'Excitatory neurons': '22.7', 'Inhibitory neurons': '13.2', 'Cone photoreceptor cells': '15.3', 'Rod photoreceptor cells': '19.2', 'Bipolar cells': '10.2', 'Horizontal cells': '8.8', 'Astrocytes': '300.3', 'Oligodendrocyte precursor cells': '25.0', 'Oligodendrocytes': '3.0', 'Microglial cells': '15.2', 'Muller glia cells': '494.0', 'Schwann cells': '0.010', 'Spermatogonia': '0.468', 'Spermatocytes': '0.017', 'Early spermatids': '-0.501', 'Late spermatids': '-0.554', 'Oocytes': '37.5', 'Cytotrophoblasts': '260.1', 'Syncytiotrophoblasts': '608.0', 'Extravillous trophoblasts': '139.8', 'Endothelial cells': '253.9', 'Lymphatic endothelial cells': '65.3', 'Cardiomyocytes': '0.222', 'Skeletal myocytes': '0.098', 'Smooth muscle cells': '177.9', 'Adipocytes': '461.3', 'Melanocytes': '0.161', 'Fibroblasts': '304.0', 'Peritubular cells': '0.446', 'Endometrial stromal cells': '334.1', 'Ovarian stromal cells': '346.0', 'Undifferentiated cells': '285.1', 'T-cells': '638.2', 'B-cells': '340.3', 'Plasma cells': '40.5', 'Nk-cells': '1103.4', 'Granulocytes': '688.0', 'Monocytes': '861.2', 'Macrophages': '465.8', 'Hofbauer cells': '814.0', 'Kupffer cells': '357.4', 'Dendritic cells': '197.3', 'Langerhans cells': '0.161', 'Erythroid cells': '0.241', 'Adipocytes (Subcutaneous)': '-0.299', 'Adipocytes (Visceral)': '-0.343', 'Breast glandular cells (progenitors)': '0.131', 'Adipocytes (Breast)': '-0.394', 'Colon enterocytes': '-0.023', 'Colon enteroendocrine cells': '0.217', 'Enteric glia cells': '-0.269', 'Mitotic cells (Colon)': '-0.027', 'Mitotic cells (Heart)': '0.346', 'Podocytes': '0.125', 'Ascending Loop of Henle cells': '0.399', 'Intercalated cells': '0.177', 'Cholangiocyte': '0.135', 'NK-cells (Liver)': '0.110', 'Respiratory ciliated cells': '-0.022', 'Mitotic cells (Lung)': '-0.084', 'NK-cells (Lung)': '0.179', 'B-cells (Lung)': '0.118', 'Alpha cells': '0.331', 'Beta cells': '0.179', 'Prostate glandular cells': '-0.210', 'Prostate basal glandular cells': '-0.083', 'Urothelial cells': '0.209', 'Keratinocyte (other)': '0.173', 'Keratinocyte (granular)': '0.021', 'Hair cortex cells': '0.089', 'Inner root sheath cells': '0.094', 'Outer root sheath cells': '0.130', 'Sebaceous gland cells': '-0.115', 'Eccrine sweat gland cells': '0.151', 'Adipocytes (Skin)': '-0.028', 'Mitotic cells (Skin)': '0.221', 'Parietal cells': '-0.625', 'Chief cells': '-0.682', 'Gastric mucous cells': '-0.407', 'Gastric enteroendocrine cells': '-0.480', 'Mitotic cells (Stomach)': '-0.038', 'Parafollicular cells': '0.044', 'Thyroid glandular cells': '0.277', 'Mitotic cells (Thyroid)': '0.064', 'Adrenal cortex cells': '0.308', 'Adrenal medulla cells': '-0.060', 'Mitotic cells (Adrenal gland)': '-0.183', 'Minor salivary glandular cells': '0.459', 'Minor salivary gland ductal cells': '0.331', 'Minor salivary gland basal cells': '-0.105', 'Mitotic cells (Minor salivary gland)': '-0.054', 'Adipocytes (Minor salivary gland)': '0.047', 'Somatotropes': '-0.420', 'Lactotropes': '-0.312', 'Gonadotropes': '0.003', 'Corticotropes': '0.260', 'Thyrotropes': '0.138', 'Undifferentiated cells (Pituitary gland)': '0.270', 'Mitotic cells (Spleen)': '-0.146', 'Platelets': '0.026', 'Erythrocytes': '0.086', 'Hematopoietic stem cells': '-0.044', 'B-cells (Spleen)': '0.064', 'NK-cells (Spleen)': '0.409', 'Amygdala excitatory': '7.3', 'Cerebellar inhibitory': '1.1', 'Cge interneuron': '45.9', 'Deep-layer corticothalamic and 6b': '14.1', 'Deep-layer intratelencephalic': '38.0', 'Deep-layer near-projecting': '1.2', 'Eccentric medium spiny neuron': '0.7', 'Hippocampal ca1-3': '19.9', 'Hippocampal ca4': '2.3', 'Hippocampal dentate gyrus': '4.3', 'Lamp5-lhx6 and chandelier': '128.3', 'Lower rhombic lip': '11.6', 'Mammillary body': '1.9', 'Medium spiny neuron': '1.0', 'Mge interneuron': '4.5', 'Midbrain-derived inhibitory': '0.9', 'Miscellaneous': '25.5', 'Splatter': '7.2', 'Thalamic excitatory': '7.1', 'Upper rhombic lip': '10.5', 'Upper-layer intratelencephalic': '20.0', 'Astrocyte': '370.6', 'Bergmann glia': '27.5', 'Central nervous system macrophage': '83.8', 'Choroid plexus epithelial cell': '22.5', 'Committed oligodendrocyte precursor': '8.1', 'Ependymal cell': '67.2', 'Oligodendrocyte': '2.0', 'Oligodendrocyte precursor cell': '16.1', 'Endothelial cell': '60.8', 'Pericyte': '2.0', 'Vascular associated smooth muscle cell': '55.7', 'Fibroblast': '13.4', 'Leukocyte': '144.3', 'Basophil': '287.7', 'Eosinophil': '1041.1', 'Neutrophil': '190.1', 'Classical monocyte': '964.7', 'Non-classical monocyte': '367.3', 'Intermediate monocyte': '673.1', 'T-reg': '72.9', 'GdT-cell': '357.7', 'MAIT T-cell': '796.8', 'Memory CD4 T-cell': '108.5', 'Naive CD4 T-cell': '194.3', 'Memory CD8 T-cell': '251.9', 'Naive CD8 T-cell': '288.7', 'Memory B-cell': '3.6', 'Naive B-cell': '3.1', 'Plasmacytoid DC': '26.9', 'Myeloid DC': '1601.3', 'NK-cell': '445.2', 'Total PBMC': '541.9', 'Vd2 gdTCR': '885.2', 'Memory CD4 T-cell Th1\\/Th17': '498.4', 'Memory CD4 T-cell Th17': '161.0', 'Memory CD4 T-cell Th2': '196.6', 'Non-Vd2 gdTCR': '746.5', 'Memory CD4 T-cell Th1': '295.0', 'Memory CD4 T-cell TFH': '62.0', 'Terminal effector memory CD4 T-cell': '435.7', 'Central memory CD8 T-cell': '315.5', 'Effector memory CD8 T-cell': '596.0', 'Terminal effector memory CD8 T-cell': '685.3', 'Non-switched memory B-cell': '62.0', 'Plasmablast': '26.1', 'Switched memory B-cell': '52.2', 'Exhausted memory B-cell': '60.3', 'Progenitor cell': '110.9', 'Memory T-reg': '56.5', 'Naive CD4 T-cell activated': '130.8', 'Naive CD8 T-cell activated': '132.0', 'Naive T-reg': '30.9'} | 4AYA | {'Adipose Tissue': 128.83166112956812, 'Adrenal Gland': 110.38519379844962, 'Bladder': 132.41619047619048, 'Blood': 51.72537136706136, 'Blood Vessel': 574.1732958801498, 'Brain': 54.30952838758517, 'Breast': 96.81759694989108, 'Cervix Uteri': 130.0442105263158, 'Colon': 131.62440308087292, 'Esophagus': 71.31968581314878, 'Fallopian Tube': 146.8, 'Heart': 61.44177351916376, 'Kidney': 76.27595505617978, 'Liver': 243.9232743362832, 'Lung': 136.04349480968858, 'Muscle': 8.885902864259029, 'Nerve': 77.88630048465266, 'Ovary': 269.01705555555554, 'Pancreas': 25.716073170731704, 'Pituitary': 79.12572438162545, 'Prostate': 100.58995918367349, 'Salivary Gland': 58.4691975308642, 'Skin': 66.79860475400774, 'Small Intestine': 80.51336898395722, 'Spleen': 91.2613692946058, 'Stomach': 54.69994428969359, 'Testis': 19.914113573407203, 'Thyroid': 133.64964777947932, 'Uterus': 92.56302816901407, 'Vagina': 100.56319871794872} | [39.93, 46.46, 52.9, 44.21, 41.4, 39.93, 35.91, 38.61, 36.44, 36.25, 34.86, 32.82, 32.01, 32.75, 31.69, 35.64, 36.35, 34.66, 33.32, 32.71, 35.01, 30.17, 37.05, 36.53, 48.19, 58.22, 64.94, 73.22, 78.33, 82.63, 85.79, 89.39, 87.89, 85.58, 83.93, 89.1, 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0.94, 0.97] | [58.8, 63.47, 75.61, 70.62, 65.86, 74.45, 58.51, 69.1, 58.42, 59.3, 61.57, 56.59, 47.73, 42.38, 57.99, 52.49, 46.44, 51.25, 42.31, 55.27, 46.76, 53.69, 51.87, 58.2, 51.02, 49.76, 52.35, 54.45, 59.65, 57.31, 65.68, 67.6, 71.79, 69.02, 70.1, 83.65, 82.89, 89.22, 93.21, 93.43, 93.03, 94.43, 95.78, 92.83, 94.08, 96.16, 95.19, 94.82, 96.35, 97.1, 97.15, 96.81, 97.1, 95.34, 92.43, 91.21, 91.98, 93.51, 95.49, 97.05, 96.97, 98.13, 97.88, 97.88, 98.33, 98.36, 98.38, 98.36, 98.29, 98.26, 98.46, 97.73, 97.47, 96.99, 96.2, 94.26, 94.75, 93.93, 92.17, 89.15, 86.01, 74.31, 65.4, 61.58, 59.53, 56.83, 54.08, 56.89, 51.93, 48.49, 39.02, 45.3, 41.84, 47.21, 55.69, 46.66, 53.75, 54.71, 52.08, 60.25, 57.86, 56.31, 55.95, 58.29, 57.09, 59.92, 57.89, 63.21, 57.18, 66.76, 65.27, 63.88, 62.75, 59.55, 56.96, 52.25, 56.14, 55.33, 46.91, 44.48, 48.31, 44.68, 42.23, 49.35, 46.97, 48.15, 50.59, 52.64, 57.98, 58.92, 53.49, 57.49, 60.33, 54.17] | [0.99, 0.86, 0.91, 0.83, 0.9, 0.9, 0.95, 0.96, 0.93, 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Forms a ternary complex composed of ADAM10, CADH1 and EPHA4, | null | null | KLRG1, SPEF1, DLGAP5, AJAP1, RAPGEF2, RAB8B, PIP5K1C, PKP2, TRPV4, CTNNB1, CAV1, DDR1, TBC1D2, CTNNA1, JUP, CTNND1, PSEN1, LIMA1, CDH1, JUP, ADAM10, CADH1 , EPHA4, | null | null | null | null | Homodimer | null | 79.91949 | 0.474025 | 69.480896 | 0.680224 | 2,872 |
P12830 | Q07820 | null | degron_data | CDH1 | MGPWSRSLSALLLLLQVSSWLCQEPEPCHPGFDAESYTFTVPRRHLERGRVLGRVNFEDCTGRQRTAYFSLDTRFKVGTDGVITVKRPLRFHNPQIHFLVYAWDSTYRKFSTKVTLNTVGHHHRPPPHQASVSGIQAELLTFPNSSPGLRRQKRDWVIPPISCPENEKGPFPKNLVQIKSNKDKEGKVFYSITGQGADTPPVGVFIIERETGWLKVTEPLDRERIATYTLFSHAVSSNGNAVEDPMEILITVTDQNDNKPEFTQEVFKGSVMEGALPGTSVMEVTATDADDDVNTYNAAIAYTILSQDPELPDKNMFTINRNTGVISVVTTGLDRESFPTYTLVVQAADLQGEGLSTTATAVITVTDTNDNPPIFNPTTYKGQVPENEANVVITTLKVTDADAPNTPAWEAVYTILNDDGGQFVVTTNPVNNDGILKTAKGLDFEAKQQYILHVAVTNVVPFEVSLTTSTATVTVDVLDVNEAPIFVPPEKRVEVSEDFGVGQEITSYTAQEPDTFMEQKITYRIWRDTANWLEINPDTGAISTRAELDREDFEHVKNSTYTALIIATDNGSPVATGTGTLLLILSDVNDNAPIPEPRTIFFCERNPKPQVINIIDADLPPNTSPFTAELTHGASANWTIQYNDPTQESIILKPKMALEVGDYKINLKLMDNQNKDQVTTLEVSVCDCEGAAGVCRKAQPVEAGLQIPAILGILGGILALLILILLLLLFLRRRAVVKEPLLPPEDDTRDNVYYYDEEGGGEEDQDFDLSQLHRGLDARPEVTRNDVAPTLMSVPRYLPRPANPDEIGNFIDENLKAADTDPTAPPYDSLLVFDYEGSGSEAASLSSLNSSESDKDQDYDYLNEWGNRFKKLADMYGGGEDD | Homo sapiens | Cell junction, adherens junction, Cell membrane, Endosome, Golgi apparatus, trans-Golgi network, Cytoplasm, Cell junction, desmosome | Tissue enhanced (parathyroid) | {'Ciliated cells': '119.1', 'Basal respiratory cells': '71.1', 'Club cells': '97.3', 'Ionocytes': '81.0', 'Mucus glandular cells': '155.0', 'Serous glandular cells': '67.8', 'Gastric mucus-secreting cells': '133.2', 'Proximal enterocytes': '140.9', 'Paneth cells': '125.1', 'Distal enterocytes': '307.5', 'Intestinal goblet cells': '173.5', 'Exocrine glandular cells': '-0.605', 'Basal prostatic cells': '68.3', 'Prostatic glandular cells': '186.7', 'Breast glandular cells': '0.773', 'Breast myoepithelial cells': '0.700', 'Glandular and luminal cells': '313.0', 'Secretory cells': '82.3', 'Basal keratinocytes': '102.5', 'Suprabasal keratinocytes': '162.6', 'Basal squamous epithelial cells': '51.0', 'Squamous epithelial cells': '106.9', 'Alveolar cells type 1': '0.437', 'Alveolar cells type 2': '0.706', 'Salivary duct cells': '95.9', 'Ductal cells': '0.541', 'Hepatocytes': '0.600', 'Cholangiocytes': '129.7', 'Proximal tubular cells': '0.042', 'Distal tubular cells': '0.0', 'Collecting duct cells': '143.9', 'Mesothelial cells': '0.799', 'Sertoli cells': '0.252', 'Granulosa cells': '12.9', 'Enteroendocrine cells': '92.4', 'Pancreatic endocrine cells': '78.1', 'Leydig cells': '0.264', 'Excitatory neurons': '0.7', 'Inhibitory neurons': '1.3', 'Cone photoreceptor cells': '0.0', 'Rod photoreceptor cells': '0.0', 'Bipolar cells': '0.2', 'Horizontal cells': '0.6', 'Astrocytes': '0.6', 'Oligodendrocyte precursor cells': '0.5', 'Oligodendrocytes': '29.9', 'Microglial cells': '0.9', 'Muller glia cells': '0.1', 'Schwann cells': '0.131', 'Spermatogonia': '0.392', 'Spermatocytes': '0.193', 'Early spermatids': '-0.217', 'Late spermatids': '-0.290', 'Oocytes': '16.9', 'Cytotrophoblasts': '119.2', 'Syncytiotrophoblasts': '45.0', 'Extravillous trophoblasts': '24.9', 'Endothelial cells': '6.1', 'Lymphatic endothelial cells': '0.4', 'Cardiomyocytes': '0.135', 'Skeletal myocytes': '0.107', 'Smooth muscle cells': '5.8', 'Adipocytes': '2.1', 'Melanocytes': '0.335', 'Fibroblasts': '6.5', 'Peritubular cells': '0.210', 'Endometrial stromal cells': '27.7', 'Ovarian stromal cells': '0.7', 'Undifferentiated cells': '101.6', 'T-cells': '2.9', 'B-cells': '4.4', 'Plasma cells': '6.1', 'Nk-cells': '0.0', 'Granulocytes': '8.4', 'Monocytes': '0.0', 'Macrophages': '6.0', 'Hofbauer cells': '4.3', 'Kupffer cells': '1.0', 'Dendritic cells': '5.9', 'Langerhans cells': '0.304', 'Erythroid cells': '0.036', 'Adipocytes (Subcutaneous)': '-0.081', 'Adipocytes (Visceral)': '-0.209', 'Breast glandular cells (progenitors)': '0.538', 'Adipocytes (Breast)': '-0.689', 'Colon enterocytes': '0.790', 'Colon enteroendocrine cells': '0.112', 'Enteric glia cells': '-0.048', 'Mitotic cells (Colon)': '0.299', 'Mitotic cells (Heart)': '0.120', 'Podocytes': '-0.118', 'Ascending Loop of Henle cells': '0.475', 'Intercalated cells': '0.212', 'Cholangiocyte': '0.090', 'NK-cells (Liver)': '-0.005', 'Respiratory ciliated cells': '-0.012', 'Mitotic cells (Lung)': '0.071', 'NK-cells (Lung)': '-0.266', 'B-cells (Lung)': '-0.296', 'Alpha cells': '0.270', 'Beta cells': '0.152', 'Prostate glandular cells': '0.764', 'Prostate basal glandular cells': '0.540', 'Urothelial cells': '0.205', 'Keratinocyte (other)': '0.510', 'Keratinocyte (granular)': '0.055', 'Hair cortex cells': '0.080', 'Inner root sheath cells': '0.131', 'Outer root sheath cells': '0.175', 'Sebaceous gland cells': '0.156', 'Eccrine sweat gland cells': '-0.207', 'Adipocytes (Skin)': '-0.244', 'Mitotic cells (Skin)': '0.442', 'Parietal cells': '0.654', 'Chief cells': '0.649', 'Gastric mucous cells': '0.781', 'Gastric enteroendocrine cells': '0.590', 'Mitotic cells (Stomach)': '0.445', 'Parafollicular cells': '0.173', 'Thyroid glandular cells': '0.865', 'Mitotic cells (Thyroid)': '-0.081', 'Adrenal cortex cells': '0.051', 'Adrenal medulla cells': '0.087', 'Mitotic cells (Adrenal gland)': '0.072', 'Minor salivary glandular cells': '0.371', 'Minor salivary gland ductal cells': '-0.142', 'Minor salivary gland basal cells': '0.582', 'Mitotic cells (Minor salivary gland)': '0.567', 'Adipocytes (Minor salivary gland)': '0.050', 'Somatotropes': '0.121', 'Lactotropes': '0.322', 'Gonadotropes': '0.330', 'Corticotropes': '0.180', 'Thyrotropes': '0.496', 'Undifferentiated cells (Pituitary gland)': '-0.108', 'Mitotic cells (Spleen)': '-0.228', 'Platelets': '-0.050', 'Erythrocytes': '-0.158', 'Hematopoietic stem cells': '-0.211', 'B-cells (Spleen)': '0.266', 'NK-cells (Spleen)': '0.309', 'Amygdala excitatory': '1.0', 'Cerebellar inhibitory': '0.9', 'Cge interneuron': '0.7', 'Deep-layer corticothalamic and 6b': '1.5', 'Deep-layer intratelencephalic': '0.7', 'Deep-layer near-projecting': '0.7', 'Eccentric medium spiny neuron': '0.6', 'Hippocampal ca1-3': '1.9', 'Hippocampal ca4': '1.2', 'Hippocampal dentate gyrus': '1.1', 'Lamp5-lhx6 and chandelier': '0.5', 'Lower rhombic lip': '0.8', 'Mammillary body': '0.6', 'Medium spiny neuron': '0.7', 'Mge interneuron': '1.7', 'Midbrain-derived inhibitory': '0.7', 'Miscellaneous': '0.9', 'Splatter': '3.8', 'Thalamic excitatory': '0.5', 'Upper rhombic lip': '0.8', 'Upper-layer intratelencephalic': '0.6', 'Astrocyte': '4.4', 'Bergmann glia': '0.2', 'Central nervous system macrophage': '0.6', 'Choroid plexus epithelial cell': '52.1', 'Committed oligodendrocyte precursor': '41.5', 'Ependymal cell': '4.8', 'Oligodendrocyte': '53.1', 'Oligodendrocyte precursor cell': '2.4', 'Endothelial cell': '0.7', 'Pericyte': '0.3', 'Vascular associated smooth muscle cell': '0.0', 'Fibroblast': '17.4', 'Leukocyte': '1.1', 'Basophil': '0.0', 'Eosinophil': '0.0', 'Neutrophil': '0.0', 'Classical monocyte': '0.0', 'Non-classical monocyte': '0.0', 'Intermediate monocyte': '0.0', 'T-reg': '2.3', 'GdT-cell': '0.0', 'MAIT T-cell': '0.0', 'Memory CD4 T-cell': '0.0', 'Naive CD4 T-cell': '0.1', 'Memory CD8 T-cell': '0.2', 'Naive CD8 T-cell': '0.3', 'Memory B-cell': '0.0', 'Naive B-cell': '0.1', 'Plasmacytoid DC': '46.6', 'Myeloid DC': '8.5', 'NK-cell': '0.1', 'Total PBMC': '0.7', 'Vd2 gdTCR': '0.0', 'Memory CD4 T-cell Th1\\/Th17': '0.1', 'Memory CD4 T-cell Th17': '0.2', 'Memory CD4 T-cell Th2': '2.9', 'Non-Vd2 gdTCR': '0.1', 'Memory CD4 T-cell Th1': '0.3', 'Memory CD4 T-cell TFH': '0.5', 'Terminal effector memory CD4 T-cell': '0.0', 'Central memory CD8 T-cell': '4.8', 'Effector memory CD8 T-cell': '0.0', 'Terminal effector memory CD8 T-cell': '0.6', 'Non-switched memory B-cell': '0.0', 'Plasmablast': '3.3', 'Switched memory B-cell': '0.0', 'Exhausted memory B-cell': '0.7', 'Progenitor cell': '2.3', 'Memory T-reg': '1.3', 'Naive CD4 T-cell activated': '0.3', 'Naive CD8 T-cell activated': '0.6', 'Naive T-reg': '0.1'} | 1O6S, 2O72, 2OMT, 2OMU, 2OMV, 2OMX, 2OMY, 2OMZ, 3FF7, 3FF8, 3L6X, 3L6Y, 4ZT1, 4ZTE, 6CXY, 6OLE, 6OLF, 6OLG, 6VEL, 7STZ, 8H62 | {'Adipose Tissue': 1.2125261088039867, 'Adrenal Gland': 0.1914223992248062, 'Bladder': 39.2033519047619, 'Blood': 1.340954264800861, 'Blood Vessel': 0.3121561692883895, 'Brain': 0.8550442199091597, 'Breast': 38.54918344226579, 'Cervix Uteri': 23.539115789473684, 'Colon': 43.41292142490372, 'Esophagus': 53.97513367404844, 'Fallopian Tube': 14.900277777777776, 'Heart': 0.119140469221835, 'Kidney': 25.040449438202245, 'Liver': 26.60802654867257, 'Lung': 35.447986366782004, 'Muscle': 0.1378936151930261, 'Nerve': 17.518468982229404, 'Ovary': 3.6515122222222223, 'Pancreas': 56.89676829268293, 'Pituitary': 24.68741660777385, 'Prostate': 61.279967346938776, 'Salivary Gland': 92.01685185185184, 'Skin': 79.77571720232172, 'Small Intestine': 71.7519320855615, 'Spleen': 10.061029045643156, 'Stomach': 58.07813805013927, 'Testis': 0.8144204986149585, 'Thyroid': 135.176797856049, 'Uterus': 1.442593943661972, 'Vagina': 86.52345512820513} | MCL1 | MFGLKRNAVIGLNLYCGGAGLGAGSGGATRPGGRLLATEKEASARREIGGGEAGAVIGGSAGASPPSTLTPDSRRVARPPPIGAEVPDVTATPARLLFFAPTRRAAPLEEMEAPAADAIMSPEEELDGYEPEPLGKRPAVLPLLELVGESGNNTSTDGSLPSTPPPAEEEEDELYRQSLEIISRYLREQATGAKDTKPMGRSGATSRKALETLRRVGDGVQRNHETAFQGMLRKLDIKNEDDVKSLSRVMIHVFSDGVTNWGRIVTLISFGAFVAKHLKTINQESCIEPLAESITDVLVRTKRDWLVKQRGWDGFVEFFHVEDLEGGIRNVLLAFAGVAGVGAGLAYLIR | Homo sapiens | Membrane, Cytoplasm, Mitochondrion, Nucleus, nucleoplasm | Tissue enhanced (bone) | {'Ciliated cells': '155.7', 'Basal respiratory cells': '139.9', 'Club cells': '201.5', 'Ionocytes': '134.7', 'Mucus glandular cells': '361.3', 'Serous glandular cells': '187.2', 'Gastric mucus-secreting cells': '212.2', 'Proximal enterocytes': '215.8', 'Paneth cells': '149.9', 'Distal enterocytes': '316.1', 'Intestinal goblet cells': '270.1', 'Exocrine glandular cells': '-0.670', 'Basal prostatic cells': '317.8', 'Prostatic glandular cells': '82.7', 'Breast glandular cells': '0.457', 'Breast myoepithelial cells': '0.594', 'Glandular and luminal cells': '352.7', 'Secretory cells': '198.7', 'Basal keratinocytes': '375.5', 'Suprabasal keratinocytes': '443.7', 'Basal squamous epithelial cells': '393.8', 'Squamous epithelial cells': '351.8', 'Alveolar cells type 1': '0.142', 'Alveolar cells type 2': '0.031', 'Salivary duct cells': '371.2', 'Ductal cells': '0.640', 'Hepatocytes': '0.175', 'Cholangiocytes': '221.3', 'Proximal tubular cells': '0.248', 'Distal tubular cells': '27.7', 'Collecting duct cells': '37.0', 'Mesothelial cells': '-0.075', 'Sertoli cells': '0.344', 'Granulosa cells': '411.0', 'Enteroendocrine cells': '199.5', 'Pancreatic endocrine cells': '47.5', 'Leydig cells': '0.522', 'Excitatory neurons': '6.3', 'Inhibitory neurons': '5.2', 'Cone photoreceptor cells': '52.7', 'Rod photoreceptor cells': '93.5', 'Bipolar cells': '48.7', 'Horizontal cells': '35.9', 'Astrocytes': '11.8', 'Oligodendrocyte precursor cells': '9.4', 'Oligodendrocytes': '6.4', 'Microglial cells': '28.6', 'Muller glia cells': '130.5', 'Schwann cells': '0.111', 'Spermatogonia': '0.466', 'Spermatocytes': '0.199', 'Early spermatids': '-0.204', 'Late spermatids': '-0.444', 'Oocytes': '18.4', 'Cytotrophoblasts': '110.3', 'Syncytiotrophoblasts': '309.7', 'Extravillous trophoblasts': '217.3', 'Endothelial cells': '237.3', 'Lymphatic endothelial cells': '312.8', 'Cardiomyocytes': '0.237', 'Skeletal myocytes': '-0.230', 'Smooth muscle cells': '231.1', 'Adipocytes': '365.2', 'Melanocytes': '0.133', 'Fibroblasts': '292.6', 'Peritubular cells': '0.423', 'Endometrial stromal cells': '318.3', 'Ovarian stromal cells': '152.0', 'Undifferentiated cells': '135.6', 'T-cells': '498.2', 'B-cells': '316.5', 'Plasma cells': '716.2', 'Nk-cells': '393.9', 'Granulocytes': '843.2', 'Monocytes': '1334.1', 'Macrophages': '727.7', 'Hofbauer cells': '487.7', 'Kupffer cells': '411.9', 'Dendritic cells': '726.8', 'Langerhans cells': '0.006', 'Erythroid cells': '0.014', 'Adipocytes (Subcutaneous)': '-0.388', 'Adipocytes (Visceral)': '0.157', 'Breast glandular cells (progenitors)': '0.400', 'Adipocytes (Breast)': '-0.643', 'Colon enterocytes': '-0.008', 'Colon enteroendocrine cells': '0.133', 'Enteric glia cells': '-0.203', 'Mitotic cells (Colon)': '0.158', 'Mitotic cells (Heart)': '0.386', 'Podocytes': '0.027', 'Ascending Loop of Henle cells': '0.144', 'Intercalated cells': '-0.056', 'Cholangiocyte': '0.381', 'NK-cells (Liver)': '-0.274', 'Respiratory ciliated cells': '0.005', 'Mitotic cells (Lung)': '-0.088', 'NK-cells (Lung)': '0.111', 'B-cells (Lung)': '0.107', 'Alpha cells': '0.282', 'Beta cells': '0.166', 'Prostate glandular cells': '-0.369', 'Prostate basal glandular cells': '0.058', 'Urothelial cells': '0.208', 'Keratinocyte (other)': '0.165', 'Keratinocyte (granular)': '-0.059', 'Hair cortex cells': '-0.184', 'Inner root sheath cells': '-0.122', 'Outer root sheath cells': '-0.076', 'Sebaceous gland cells': '-0.116', 'Eccrine sweat gland cells': '-0.033', 'Adipocytes (Skin)': '-0.155', 'Mitotic cells (Skin)': '0.099', 'Parietal cells': '-0.551', 'Chief cells': '-0.486', 'Gastric mucous cells': '-0.321', 'Gastric enteroendocrine cells': '-0.369', 'Mitotic cells (Stomach)': '-0.029', 'Parafollicular cells': '0.016', 'Thyroid glandular cells': '0.007', 'Mitotic cells (Thyroid)': '0.119', 'Adrenal cortex cells': '0.176', 'Adrenal medulla cells': '-0.019', 'Mitotic cells (Adrenal gland)': '0.093', 'Minor salivary glandular cells': '0.636', 'Minor salivary gland ductal cells': '0.048', 'Minor salivary gland basal cells': '0.401', 'Mitotic cells (Minor salivary gland)': '0.462', 'Adipocytes (Minor salivary gland)': '0.231', 'Somatotropes': '-0.347', 'Lactotropes': '-0.410', 'Gonadotropes': '-0.039', 'Corticotropes': '-0.114', 'Thyrotropes': '-0.067', 'Undifferentiated cells (Pituitary gland)': '0.204', 'Mitotic cells (Spleen)': '0.088', 'Platelets': '0.156', 'Erythrocytes': '-0.043', 'Hematopoietic stem cells': '0.013', 'B-cells (Spleen)': '0.101', 'NK-cells (Spleen)': '0.233', 'Amygdala excitatory': '8.2', 'Cerebellar inhibitory': '9.8', 'Cge interneuron': '9.7', 'Deep-layer corticothalamic and 6b': '9.5', 'Deep-layer intratelencephalic': '8.5', 'Deep-layer near-projecting': '6.7', 'Eccentric medium spiny neuron': '10.8', 'Hippocampal ca1-3': '8.9', 'Hippocampal ca4': '5.9', 'Hippocampal dentate gyrus': '7.5', 'Lamp5-lhx6 and chandelier': '7.9', 'Lower rhombic lip': '5.1', 'Mammillary body': '5.6', 'Medium spiny neuron': '7.5', 'Mge interneuron': '8.0', 'Midbrain-derived inhibitory': '16.8', 'Miscellaneous': '10.0', 'Splatter': '8.0', 'Thalamic excitatory': '8.0', 'Upper rhombic lip': '13.2', 'Upper-layer intratelencephalic': '8.0', 'Astrocyte': '40.9', 'Bergmann glia': '14.2', 'Central nervous system macrophage': '47.0', 'Choroid plexus epithelial cell': '26.1', 'Committed oligodendrocyte precursor': '13.8', 'Ependymal cell': '22.6', 'Oligodendrocyte': '11.5', 'Oligodendrocyte precursor cell': '13.6', 'Endothelial cell': '125.3', 'Pericyte': '32.7', 'Vascular associated smooth muscle cell': '61.1', 'Fibroblast': '46.1', 'Leukocyte': '128.3', 'Basophil': '197.9', 'Eosinophil': '51.9', 'Neutrophil': '2173.5', 'Classical monocyte': '5002.1', 'Non-classical monocyte': '1782.9', 'Intermediate monocyte': '446.6', 'T-reg': '152.7', 'GdT-cell': '15.0', 'MAIT T-cell': '204.8', 'Memory CD4 T-cell': '19.1', 'Naive CD4 T-cell': '1084.0', 'Memory CD8 T-cell': '16.6', 'Naive CD8 T-cell': '929.5', 'Memory B-cell': '12.6', 'Naive B-cell': '452.6', 'Plasmacytoid DC': '115.0', 'Myeloid DC': '479.2', 'NK-cell': '983.4', 'Total PBMC': '280.7', 'Vd2 gdTCR': '171.8', 'Memory CD4 T-cell Th1\\/Th17': '1242.0', 'Memory CD4 T-cell Th17': '1070.7', 'Memory CD4 T-cell Th2': '1117.5', 'Non-Vd2 gdTCR': '142.1', 'Memory CD4 T-cell Th1': '897.5', 'Memory CD4 T-cell TFH': '838.0', 'Terminal effector memory CD4 T-cell': '161.6', 'Central memory CD8 T-cell': '190.7', 'Effector memory CD8 T-cell': '173.4', 'Terminal effector memory CD8 T-cell': '144.5', 'Non-switched memory B-cell': '124.7', 'Plasmablast': '248.3', 'Switched memory B-cell': '145.6', 'Exhausted memory B-cell': '153.7', 'Progenitor cell': '85.4', 'Memory T-reg': '852.7', 'Naive CD4 T-cell activated': '1072.1', 'Naive CD8 T-cell activated': '1057.4', 'Naive T-reg': '935.2'} | 2KBW, 2MHS, 2NL9, 2NLA, 2PQK, 3D7V, 3IO9, 3KJ0, 3KJ1, 3KJ2, 3KZ0, 3MK8, 3PK1, 3TWU, 3WIX, 3WIY, 4BPI, 4BPJ, 4HW2, 4HW3, 4HW4, 4OQ5, 4OQ6, 4WGI, 4WMR, 4WMS, 4WMT, 4WMU, 4WMV, 4WMW, 4WMX, 4ZBF, 4ZBI, 5C3F, 5C6H, 5FC4, 5FDO, 5FDR, 5IEZ, 5IF4, 5JSB, 5KU9, 5LOF, 5MES, 5MEV, 5UUM, 5VKC, 5VX2, 5W89, 5W8F, 6B4L, 6B4U, 6BW2, 6BW8, 6FS0, 6FS1, 6FS2, 6MBD, 6MBE, 6NE5, 6O4U, 6O6F, 6O6G, 6OQB, 6OQC, 6OQD, 6OQN, 6OVC, 6P3P, 6QB3, 6QB4, 6QB6, 6QFC, 6QFI, 6QFM, 6QFQ, 6QGD, 6QXJ, 6QYK, 6QYL, 6QYN, 6QYO, 6QYP, 6QZ5, 6QZ6, 6QZ7, 6QZ8, 6QZB, 6STJ, 6U63, 6U64, 6U65, 6U67, 6U6F, 6UA3, 6UAB, 6UD2, 6UDI, 6UDT, 6UDU, 6UDV, 6UDX, 6UDY, 6VBX, 6YBG, 6YBJ, 6YBK, 6YBL, 6ZIE, 7NB4, 7NB7, 7XGE, 8AV9, 8EKX, 8EL0, 8EL1, 8G3S, 8G3T, 8G3U, 8G3W, 8G3X, 8G3Y, 8H7B, 8IQM, 8QSO, 8SVY, 8T6F, 8VJP | {'Adipose Tissue': 350.47304817275744, 'Adrenal Gland': 169.51244186046512, 'Bladder': 214.9771428571429, 'Blood': 417.495780409042, 'Blood Vessel': 330.1543970037453, 'Brain': 56.15663701741105, 'Breast': 273.10058823529414, 'Cervix Uteri': 182.5421052631579, 'Colon': 227.17679075738127, 'Esophagus': 254.64896193771625, 'Fallopian Tube': 440.5, 'Heart': 97.38246341463416, 'Kidney': 104.11067415730338, 'Liver': 144.41384955752213, 'Lung': 500.5269896193771, 'Muscle': 124.42875466998754, 'Nerve': 298.8604200323102, 'Ovary': 230.5691111111111, 'Pancreas': 108.16524390243902, 'Pituitary': 163.3028621908127, 'Prostate': 160.88604081632653, 'Salivary Gland': 205.08827160493829, 'Skin': 310.05712548369263, 'Small Intestine': 230.6979679144385, 'Spleen': 292.63236514522816, 'Stomach': 235.7885515320334, 'Testis': 92.07828254847648, 'Thyroid': 237.49560490045943, 'Uterus': 225.58830985915495, 'Vagina': 252.8044871794872} | [39.93, 46.46, 52.9, 44.21, 41.4, 39.93, 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85.27, 87.24, 89.47, 93.32, 89.4, 90.57, 92.74, 93.95, 90.98, 93.58, 96.32, 95.03, 93.81, 95.48, 97.2, 94.93, 94.66, 96.17, 96.2, 94.52, 94.6, 95.01, 95.09, 94.05, 93.81, 93.07, 93.36, 93.64, 93.02, 95.14, 94.59, 93.83, 94.74, 96.49, 94.8, 93.24, 95.36, 96.44, 93.59, 90.84, 93.48, 95.05, 91.28, 90.26, 92.29, 93.81, 94.36, 94.9, 95.83, 95.67, 95.52, 93.93, 94.81, 95.35, 97.24, 95.9, 94.86, 95.85, 95.83, 92.86, 89.85, 90.02, 84.4, 60.2, 50.93, 44.91, 51.4, 53.96, 49.57, 49.79, 53.49, 54.54, 53.99, 54.28, 53.47, 53.06, 52.78, 50.94, 47.54, 46.05, 50.88, 46.19, 43.56, 48.95, 42.77, 43.96, 38.28, 40.79, 42.69, 41.77, 44.82, 49.97, 39.7] | [0.98, 0.95, 0.81, 0.9, 0.95, 0.97, 0.97, 0.94, 0.73, 0.6, 0.57, 0.37, 0.41, 0.33, 0.75, 0.8, 0.78, 0.94, 1.0, 1.0, 1.0, 0.98, 1.0, 0.99, 0.99, 1.0, 0.98, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 0.98, 1.0, 0.96, 1.0, 1.0, 1.0, 1.0, 0.93, 1.0, 0.88, 1.0, 0.86, 1.0, 0.81, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 0.98, 0.98, 0.99, 0.98, 1.0, 0.97, 0.99, 1.0, 1.0, 1.0, 1.0, 1.0, 0.94, 0.92, 0.9, 0.92, 0.93, 0.87, 0.84, 0.88, 0.84, 0.95, 0.85, 0.87, 0.88, 0.92, 0.87, 0.89, 0.87, 0.86, 0.85, 0.79, 0.88, 0.83, 0.87, 0.9, 0.83, 0.95, 0.98, 0.93, 0.86, 0.89, 0.88, 0.79, 0.94, 0.96, 0.97, 0.97, 0.96, 0.99, 0.99, 0.99, 1.0, 1.0, 0.98, 1.0, 0.97, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 0.99, 1.0, 0.94, 0.96, 0.83, 0.95, 0.96, 0.95, 0.96, 0.97, 0.98, 0.98, 0.98, 0.92, 0.97, 0.92, 0.97, 0.9, 0.93, 0.98, 0.91, 0.87, 0.97, 0.96, 0.9, 0.95, 0.94, 0.9, 0.96, 0.79, 0.96, 0.89, 0.99, 1.0, 1.0, 1.0, 0.99, 1.0, 0.99, 1.0, 1.0, 0.99, 0.96, 0.92, 0.9, 0.92, 0.91, 0.69, 0.52, 0.57, 0.72, 0.58, 0.66, 0.44, 0.65, 0.28, 0.13, 0.24, 0.41, 0.11, 0.01, 0.22, 0.17, 0.0, 0.0, 0.06, 0.07, 0.0, 0.0, 0.39, 0.09, 0.18, 0.13, 0.48, 0.77, 0.57, 0.72, 0.33, 0.89, 0.77, 0.89, 0.16, 0.42, 0.89, 0.29, 0.04, 0.53, 0.18, 0.01, 0.53, 0.57, 0.0, 0.02, 0.56, 0.08, 0.0, 0.25, 0.59, 0.11, 0.0, 0.29, 0.17, 0.03, 0.06, 0.73, 0.83, 0.2, 0.48, 0.78, 0.36, 0.01, 0.36, 0.39, 0.2, 0.12, 0.77, 0.84, 0.29, 0.5, 0.04, 0.6, 0.41, 0.43, 0.67, 0.23, 0.01, 0.52, 0.44, 0.03, 0.17, 0.73, 0.29, 0.04, 0.56, 0.42, 0.17, 0.07, 0.65, 0.56, 0.62, 0.4, 0.19, 0.28, 0.04, 0.11, 0.18, 0.0, 0.02, 0.1, 0.07, 0.0, 0.0, 0.09, 0.04, 0.0, 0.14, 0.0, 0.0, 0.33, 0.26, 0.0, 0.38, 0.77, 0.38, 0.77, 0.28, 0.37, 0.73, 0.0, 0.07, 0.38, 0.3, 0.0, 0.0, 0.43, 0.2, 0.0, 0.0, 0.26, 0.07, 0.03, 0.0, 0.71, 0.65, 0.16, 0.25, 0.82, 0.23, 0.04, 0.62, 0.67, 0.35, 0.62, 0.11, 0.03, 0.46, 0.13, 0.0, 0.17, 0.5, 0.43, 0.07, 0.71, 0.39, 0.91, 0.75, 0.79, 0.83, 0.26, 0.22, 0.56, 0.66, 0.4, 0.25, 0.59, 0.58, 0.28, 0.23, 0.59, 0.78, 0.24, 0.77, 0.91, 0.65, 0.55, 0.82, 0.52, 0.44, 0.73, 0.88, 0.71, 0.75, 0.91] | null | Component of an E-cadherin/ catenin adhesion complex composed of at least E-cadherin/CDH1, beta-catenin/CTNNB1 or gamma-catenin/JUP, and potentially alpha-catenin/CTNNA1. Forms a ternary complex composed of ADAM10, CADH1 and EPHA4, | null | null | KLRG1, SPEF1, DLGAP5, AJAP1, RAPGEF2, RAB8B, PIP5K1C, PKP2, TRPV4, CTNNB1, CAV1, DDR1, TBC1D2, CTNNA1, JUP, CTNND1, PSEN1, LIMA1, CDH1, JUP, ADAM10, CADH1 , EPHA4, | null | null | null | null | Homodimer | null | 79.91949 | 0.474025 | 63.504286 | 0.625571 | 2,174 |
P12830 | Q08050-3 | null | degron_data | CDH1 | MGPWSRSLSALLLLLQVSSWLCQEPEPCHPGFDAESYTFTVPRRHLERGRVLGRVNFEDCTGRQRTAYFSLDTRFKVGTDGVITVKRPLRFHNPQIHFLVYAWDSTYRKFSTKVTLNTVGHHHRPPPHQASVSGIQAELLTFPNSSPGLRRQKRDWVIPPISCPENEKGPFPKNLVQIKSNKDKEGKVFYSITGQGADTPPVGVFIIERETGWLKVTEPLDRERIATYTLFSHAVSSNGNAVEDPMEILITVTDQNDNKPEFTQEVFKGSVMEGALPGTSVMEVTATDADDDVNTYNAAIAYTILSQDPELPDKNMFTINRNTGVISVVTTGLDRESFPTYTLVVQAADLQGEGLSTTATAVITVTDTNDNPPIFNPTTYKGQVPENEANVVITTLKVTDADAPNTPAWEAVYTILNDDGGQFVVTTNPVNNDGILKTAKGLDFEAKQQYILHVAVTNVVPFEVSLTTSTATVTVDVLDVNEAPIFVPPEKRVEVSEDFGVGQEITSYTAQEPDTFMEQKITYRIWRDTANWLEINPDTGAISTRAELDREDFEHVKNSTYTALIIATDNGSPVATGTGTLLLILSDVNDNAPIPEPRTIFFCERNPKPQVINIIDADLPPNTSPFTAELTHGASANWTIQYNDPTQESIILKPKMALEVGDYKINLKLMDNQNKDQVTTLEVSVCDCEGAAGVCRKAQPVEAGLQIPAILGILGGILALLILILLLLLFLRRRAVVKEPLLPPEDDTRDNVYYYDEEGGGEEDQDFDLSQLHRGLDARPEVTRNDVAPTLMSVPRYLPRPANPDEIGNFIDENLKAADTDPTAPPYDSLLVFDYEGSGSEAASLSSLNSSESDKDQDYDYLNEWGNRFKKLADMYGGGEDD | Homo sapiens | Cell junction, adherens junction, Cell membrane, Endosome, Golgi apparatus, trans-Golgi network, Cytoplasm, Cell junction, desmosome | Tissue enhanced (parathyroid) | {'Ciliated cells': '119.1', 'Basal respiratory cells': '71.1', 'Club cells': '97.3', 'Ionocytes': '81.0', 'Mucus glandular cells': '155.0', 'Serous glandular cells': '67.8', 'Gastric mucus-secreting cells': '133.2', 'Proximal enterocytes': '140.9', 'Paneth cells': '125.1', 'Distal enterocytes': '307.5', 'Intestinal goblet cells': '173.5', 'Exocrine glandular cells': '-0.605', 'Basal prostatic cells': '68.3', 'Prostatic glandular cells': '186.7', 'Breast glandular cells': '0.773', 'Breast myoepithelial cells': '0.700', 'Glandular and luminal cells': '313.0', 'Secretory cells': '82.3', 'Basal keratinocytes': '102.5', 'Suprabasal keratinocytes': '162.6', 'Basal squamous epithelial cells': '51.0', 'Squamous epithelial cells': '106.9', 'Alveolar cells type 1': '0.437', 'Alveolar cells type 2': '0.706', 'Salivary duct cells': '95.9', 'Ductal cells': '0.541', 'Hepatocytes': '0.600', 'Cholangiocytes': '129.7', 'Proximal tubular cells': '0.042', 'Distal tubular cells': '0.0', 'Collecting duct cells': '143.9', 'Mesothelial cells': '0.799', 'Sertoli cells': '0.252', 'Granulosa cells': '12.9', 'Enteroendocrine cells': '92.4', 'Pancreatic endocrine cells': '78.1', 'Leydig cells': '0.264', 'Excitatory neurons': '0.7', 'Inhibitory neurons': '1.3', 'Cone photoreceptor cells': '0.0', 'Rod photoreceptor cells': '0.0', 'Bipolar cells': '0.2', 'Horizontal cells': '0.6', 'Astrocytes': '0.6', 'Oligodendrocyte precursor cells': '0.5', 'Oligodendrocytes': '29.9', 'Microglial cells': '0.9', 'Muller glia cells': '0.1', 'Schwann cells': '0.131', 'Spermatogonia': '0.392', 'Spermatocytes': '0.193', 'Early spermatids': '-0.217', 'Late spermatids': '-0.290', 'Oocytes': '16.9', 'Cytotrophoblasts': '119.2', 'Syncytiotrophoblasts': '45.0', 'Extravillous trophoblasts': '24.9', 'Endothelial cells': '6.1', 'Lymphatic endothelial cells': '0.4', 'Cardiomyocytes': '0.135', 'Skeletal myocytes': '0.107', 'Smooth muscle cells': '5.8', 'Adipocytes': '2.1', 'Melanocytes': '0.335', 'Fibroblasts': '6.5', 'Peritubular cells': '0.210', 'Endometrial stromal cells': '27.7', 'Ovarian stromal cells': '0.7', 'Undifferentiated cells': '101.6', 'T-cells': '2.9', 'B-cells': '4.4', 'Plasma cells': '6.1', 'Nk-cells': '0.0', 'Granulocytes': '8.4', 'Monocytes': '0.0', 'Macrophages': '6.0', 'Hofbauer cells': '4.3', 'Kupffer cells': '1.0', 'Dendritic cells': '5.9', 'Langerhans cells': '0.304', 'Erythroid cells': '0.036', 'Adipocytes (Subcutaneous)': '-0.081', 'Adipocytes (Visceral)': '-0.209', 'Breast glandular cells (progenitors)': '0.538', 'Adipocytes (Breast)': '-0.689', 'Colon enterocytes': '0.790', 'Colon enteroendocrine cells': '0.112', 'Enteric glia cells': '-0.048', 'Mitotic cells (Colon)': '0.299', 'Mitotic cells (Heart)': '0.120', 'Podocytes': '-0.118', 'Ascending Loop of Henle cells': '0.475', 'Intercalated cells': '0.212', 'Cholangiocyte': '0.090', 'NK-cells (Liver)': '-0.005', 'Respiratory ciliated cells': '-0.012', 'Mitotic cells (Lung)': '0.071', 'NK-cells (Lung)': '-0.266', 'B-cells (Lung)': '-0.296', 'Alpha cells': '0.270', 'Beta cells': '0.152', 'Prostate glandular cells': '0.764', 'Prostate basal glandular cells': '0.540', 'Urothelial cells': '0.205', 'Keratinocyte (other)': '0.510', 'Keratinocyte (granular)': '0.055', 'Hair cortex cells': '0.080', 'Inner root sheath cells': '0.131', 'Outer root sheath cells': '0.175', 'Sebaceous gland cells': '0.156', 'Eccrine sweat gland cells': '-0.207', 'Adipocytes (Skin)': '-0.244', 'Mitotic cells (Skin)': '0.442', 'Parietal cells': '0.654', 'Chief cells': '0.649', 'Gastric mucous cells': '0.781', 'Gastric enteroendocrine cells': '0.590', 'Mitotic cells (Stomach)': '0.445', 'Parafollicular cells': '0.173', 'Thyroid glandular cells': '0.865', 'Mitotic cells (Thyroid)': '-0.081', 'Adrenal cortex cells': '0.051', 'Adrenal medulla cells': '0.087', 'Mitotic cells (Adrenal gland)': '0.072', 'Minor salivary glandular cells': '0.371', 'Minor salivary gland ductal cells': '-0.142', 'Minor salivary gland basal cells': '0.582', 'Mitotic cells (Minor salivary gland)': '0.567', 'Adipocytes (Minor salivary gland)': '0.050', 'Somatotropes': '0.121', 'Lactotropes': '0.322', 'Gonadotropes': '0.330', 'Corticotropes': '0.180', 'Thyrotropes': '0.496', 'Undifferentiated cells (Pituitary gland)': '-0.108', 'Mitotic cells (Spleen)': '-0.228', 'Platelets': '-0.050', 'Erythrocytes': '-0.158', 'Hematopoietic stem cells': '-0.211', 'B-cells (Spleen)': '0.266', 'NK-cells (Spleen)': '0.309', 'Amygdala excitatory': '1.0', 'Cerebellar inhibitory': '0.9', 'Cge interneuron': '0.7', 'Deep-layer corticothalamic and 6b': '1.5', 'Deep-layer intratelencephalic': '0.7', 'Deep-layer near-projecting': '0.7', 'Eccentric medium spiny neuron': '0.6', 'Hippocampal ca1-3': '1.9', 'Hippocampal ca4': '1.2', 'Hippocampal dentate gyrus': '1.1', 'Lamp5-lhx6 and chandelier': '0.5', 'Lower rhombic lip': '0.8', 'Mammillary body': '0.6', 'Medium spiny neuron': '0.7', 'Mge interneuron': '1.7', 'Midbrain-derived inhibitory': '0.7', 'Miscellaneous': '0.9', 'Splatter': '3.8', 'Thalamic excitatory': '0.5', 'Upper rhombic lip': '0.8', 'Upper-layer intratelencephalic': '0.6', 'Astrocyte': '4.4', 'Bergmann glia': '0.2', 'Central nervous system macrophage': '0.6', 'Choroid plexus epithelial cell': '52.1', 'Committed oligodendrocyte precursor': '41.5', 'Ependymal cell': '4.8', 'Oligodendrocyte': '53.1', 'Oligodendrocyte precursor cell': '2.4', 'Endothelial cell': '0.7', 'Pericyte': '0.3', 'Vascular associated smooth muscle cell': '0.0', 'Fibroblast': '17.4', 'Leukocyte': '1.1', 'Basophil': '0.0', 'Eosinophil': '0.0', 'Neutrophil': '0.0', 'Classical monocyte': '0.0', 'Non-classical monocyte': '0.0', 'Intermediate monocyte': '0.0', 'T-reg': '2.3', 'GdT-cell': '0.0', 'MAIT T-cell': '0.0', 'Memory CD4 T-cell': '0.0', 'Naive CD4 T-cell': '0.1', 'Memory CD8 T-cell': '0.2', 'Naive CD8 T-cell': '0.3', 'Memory B-cell': '0.0', 'Naive B-cell': '0.1', 'Plasmacytoid DC': '46.6', 'Myeloid DC': '8.5', 'NK-cell': '0.1', 'Total PBMC': '0.7', 'Vd2 gdTCR': '0.0', 'Memory CD4 T-cell Th1\\/Th17': '0.1', 'Memory CD4 T-cell Th17': '0.2', 'Memory CD4 T-cell Th2': '2.9', 'Non-Vd2 gdTCR': '0.1', 'Memory CD4 T-cell Th1': '0.3', 'Memory CD4 T-cell TFH': '0.5', 'Terminal effector memory CD4 T-cell': '0.0', 'Central memory CD8 T-cell': '4.8', 'Effector memory CD8 T-cell': '0.0', 'Terminal effector memory CD8 T-cell': '0.6', 'Non-switched memory B-cell': '0.0', 'Plasmablast': '3.3', 'Switched memory B-cell': '0.0', 'Exhausted memory B-cell': '0.7', 'Progenitor cell': '2.3', 'Memory T-reg': '1.3', 'Naive CD4 T-cell activated': '0.3', 'Naive CD8 T-cell activated': '0.6', 'Naive T-reg': '0.1'} | 1O6S, 2O72, 2OMT, 2OMU, 2OMV, 2OMX, 2OMY, 2OMZ, 3FF7, 3FF8, 3L6X, 3L6Y, 4ZT1, 4ZTE, 6CXY, 6OLE, 6OLF, 6OLG, 6VEL, 7STZ, 8H62 | {'Adipose Tissue': 1.2125261088039867, 'Adrenal Gland': 0.1914223992248062, 'Bladder': 39.2033519047619, 'Blood': 1.340954264800861, 'Blood Vessel': 0.3121561692883895, 'Brain': 0.8550442199091597, 'Breast': 38.54918344226579, 'Cervix Uteri': 23.539115789473684, 'Colon': 43.41292142490372, 'Esophagus': 53.97513367404844, 'Fallopian Tube': 14.900277777777776, 'Heart': 0.119140469221835, 'Kidney': 25.040449438202245, 'Liver': 26.60802654867257, 'Lung': 35.447986366782004, 'Muscle': 0.1378936151930261, 'Nerve': 17.518468982229404, 'Ovary': 3.6515122222222223, 'Pancreas': 56.89676829268293, 'Pituitary': 24.68741660777385, 'Prostate': 61.279967346938776, 'Salivary Gland': 92.01685185185184, 'Skin': 79.77571720232172, 'Small Intestine': 71.7519320855615, 'Spleen': 10.061029045643156, 'Stomach': 58.07813805013927, 'Testis': 0.8144204986149585, 'Thyroid': 135.176797856049, 'Uterus': 1.442593943661972, 'Vagina': 86.52345512820513} | FOXM1 | MKTSPRRPLILKRRRLPLPVQNAPSETSEEEPKRSPAQQESNQAEASKEVAESNSCKFPAGIKIINHPTMPNTQVVAIPNNANIHSIITALTAKGKESGSSGPNKFILISCGGAPTQPPGLRPQTQTSYDAKRTEVTLETLGPKPAARDVNLPRPPGALCEQKRETCADGEAAGCTINNSLSNIQWLRKMSSDGLGSRSIKQEMEEKENCHLEQRQVKVEEPSRPSASWQNSVSERPPYSYMAMIQFAINSTERKRMTLKDIYTWIEDHFPYFKHIAKPGWKNSIRHNLSLHDMFVRETSANGKVSFWTIHPSANRYLTLDQVFKPLDPGSPQLPEHLESQQKRPNPELRRNMTIKTELPLGARRKMKPLLPRVSSYLVPIQFPVNQSLVLQPSVKVPLPLAASLMSSELARHSKRVRIAPKVFGEQVVFGYMSKFFSGDLRDFGTPITSLFNFIFLCLSVLLAEEGIAPLSSAGPGKEEKLLFGEGFSPLLPVQTIKEEEIQPGEEMPHLARPIKVESPPLEEWPSPAPSFKEESSHSWEDSSQSPTPRPKKSYSGLRSPTRCVSEMLVIQHRERRERSRSRRKQHLLPPCVDEPELLFSEGPSTSRWAAELPFPADSSDPASQLSYSQEVGGPFKTPIKETLPISSTPSKSVLPRTPESWRLTPPAKVGGLDFSPVQTSQGASDPLPDPLGLMDLSTTPLQSAPPLESPQRLLSSEPLDLISVPFGNSSPSDIDVPKPGSPEPQVSGLAANRSLTEGLVLDTMNDSLSKILLDISFPGLDEDPLGPDNINWSQFIPELQ | Homo sapiens | null | Not found | {} | null | {'Adipose Tissue': 1.8794906478405315, 'Adrenal Gland': 2.2110558139534886, 'Bladder': 2.0431333333333335, 'Blood': 12.430574090419803, 'Blood Vessel': 1.2020308239700377, 'Brain': 0.7483524451173353, 'Breast': 1.8677209150326797, 'Cervix Uteri': 3.321878947368421, 'Colon': 4.375473363286265, 'Esophagus': 7.357720498269896, 'Fallopian Tube': 1.9783999999999995, 'Heart': 0.6873927874564459, 'Kidney': 1.740594382022472, 'Liver': 1.9241300884955752, 'Lung': 4.729498442906574, 'Muscle': 0.2481442303860523, 'Nerve': 1.7678321486268174, 'Ovary': 1.9992594444444445, 'Pancreas': 0.778709237804878, 'Pituitary': 1.3677240282685512, 'Prostate': 3.2848930612244898, 'Salivary Gland': 3.992593827160494, 'Skin': 19.034247927031508, 'Small Intestine': 8.00771818181818, 'Spleen': 8.543099585062242, 'Stomach': 4.267721727019499, 'Testis': 42.10467590027701, 'Thyroid': 2.986481010719755, 'Uterus': 1.4417816901408451, 'Vagina': 7.3760955128205135} | [39.93, 46.46, 52.9, 44.21, 41.4, 39.93, 35.91, 38.61, 36.44, 36.25, 34.86, 32.82, 32.01, 32.75, 31.69, 35.64, 36.35, 34.66, 33.32, 32.71, 35.01, 30.17, 37.05, 36.53, 48.19, 58.22, 64.94, 73.22, 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0.73, 0.39, 0.06, 0.61, 0.75, 0.47, 0.19, 0.87, 0.7, 0.97, 0.94, 0.97] | null | null | null | Component of an E-cadherin/ catenin adhesion complex composed of at least E-cadherin/CDH1, beta-catenin/CTNNB1 or gamma-catenin/JUP, and potentially alpha-catenin/CTNNA1. Forms a ternary complex composed of ADAM10, CADH1 and EPHA4, | null | null | KLRG1, SPEF1, DLGAP5, AJAP1, RAPGEF2, RAB8B, PIP5K1C, PKP2, TRPV4, CTNNB1, CAV1, DDR1, TBC1D2, CTNNA1, JUP, CTNND1, PSEN1, LIMA1, CDH1, JUP, ADAM10, CADH1 , EPHA4, | null | null | null | null | Homodimer | null | 79.91949 | 0.474025 | null | null | 799 |
P12830 | Q12834 | null | degron_data | CDH1 | MGPWSRSLSALLLLLQVSSWLCQEPEPCHPGFDAESYTFTVPRRHLERGRVLGRVNFEDCTGRQRTAYFSLDTRFKVGTDGVITVKRPLRFHNPQIHFLVYAWDSTYRKFSTKVTLNTVGHHHRPPPHQASVSGIQAELLTFPNSSPGLRRQKRDWVIPPISCPENEKGPFPKNLVQIKSNKDKEGKVFYSITGQGADTPPVGVFIIERETGWLKVTEPLDRERIATYTLFSHAVSSNGNAVEDPMEILITVTDQNDNKPEFTQEVFKGSVMEGALPGTSVMEVTATDADDDVNTYNAAIAYTILSQDPELPDKNMFTINRNTGVISVVTTGLDRESFPTYTLVVQAADLQGEGLSTTATAVITVTDTNDNPPIFNPTTYKGQVPENEANVVITTLKVTDADAPNTPAWEAVYTILNDDGGQFVVTTNPVNNDGILKTAKGLDFEAKQQYILHVAVTNVVPFEVSLTTSTATVTVDVLDVNEAPIFVPPEKRVEVSEDFGVGQEITSYTAQEPDTFMEQKITYRIWRDTANWLEINPDTGAISTRAELDREDFEHVKNSTYTALIIATDNGSPVATGTGTLLLILSDVNDNAPIPEPRTIFFCERNPKPQVINIIDADLPPNTSPFTAELTHGASANWTIQYNDPTQESIILKPKMALEVGDYKINLKLMDNQNKDQVTTLEVSVCDCEGAAGVCRKAQPVEAGLQIPAILGILGGILALLILILLLLLFLRRRAVVKEPLLPPEDDTRDNVYYYDEEGGGEEDQDFDLSQLHRGLDARPEVTRNDVAPTLMSVPRYLPRPANPDEIGNFIDENLKAADTDPTAPPYDSLLVFDYEGSGSEAASLSSLNSSESDKDQDYDYLNEWGNRFKKLADMYGGGEDD | Homo sapiens | Cell junction, adherens junction, Cell membrane, Endosome, Golgi apparatus, trans-Golgi network, Cytoplasm, Cell junction, desmosome | Tissue enhanced (parathyroid) | {'Ciliated cells': '119.1', 'Basal respiratory cells': '71.1', 'Club cells': '97.3', 'Ionocytes': '81.0', 'Mucus glandular cells': '155.0', 'Serous glandular cells': '67.8', 'Gastric mucus-secreting cells': '133.2', 'Proximal enterocytes': '140.9', 'Paneth cells': '125.1', 'Distal enterocytes': '307.5', 'Intestinal goblet cells': '173.5', 'Exocrine glandular cells': '-0.605', 'Basal prostatic cells': '68.3', 'Prostatic glandular cells': '186.7', 'Breast glandular cells': '0.773', 'Breast myoepithelial cells': '0.700', 'Glandular and luminal cells': '313.0', 'Secretory cells': '82.3', 'Basal keratinocytes': '102.5', 'Suprabasal keratinocytes': '162.6', 'Basal squamous epithelial cells': '51.0', 'Squamous epithelial cells': '106.9', 'Alveolar cells type 1': '0.437', 'Alveolar cells type 2': '0.706', 'Salivary duct cells': '95.9', 'Ductal cells': '0.541', 'Hepatocytes': '0.600', 'Cholangiocytes': '129.7', 'Proximal tubular cells': '0.042', 'Distal tubular cells': '0.0', 'Collecting duct cells': '143.9', 'Mesothelial cells': '0.799', 'Sertoli cells': '0.252', 'Granulosa cells': '12.9', 'Enteroendocrine cells': '92.4', 'Pancreatic endocrine cells': '78.1', 'Leydig cells': '0.264', 'Excitatory neurons': '0.7', 'Inhibitory neurons': '1.3', 'Cone photoreceptor cells': '0.0', 'Rod photoreceptor cells': '0.0', 'Bipolar cells': '0.2', 'Horizontal cells': '0.6', 'Astrocytes': '0.6', 'Oligodendrocyte precursor cells': '0.5', 'Oligodendrocytes': '29.9', 'Microglial cells': '0.9', 'Muller glia cells': '0.1', 'Schwann cells': '0.131', 'Spermatogonia': '0.392', 'Spermatocytes': '0.193', 'Early spermatids': '-0.217', 'Late spermatids': '-0.290', 'Oocytes': '16.9', 'Cytotrophoblasts': '119.2', 'Syncytiotrophoblasts': '45.0', 'Extravillous trophoblasts': '24.9', 'Endothelial cells': '6.1', 'Lymphatic endothelial cells': '0.4', 'Cardiomyocytes': '0.135', 'Skeletal myocytes': '0.107', 'Smooth muscle cells': '5.8', 'Adipocytes': '2.1', 'Melanocytes': '0.335', 'Fibroblasts': '6.5', 'Peritubular cells': '0.210', 'Endometrial stromal cells': '27.7', 'Ovarian stromal cells': '0.7', 'Undifferentiated cells': '101.6', 'T-cells': '2.9', 'B-cells': '4.4', 'Plasma cells': '6.1', 'Nk-cells': '0.0', 'Granulocytes': '8.4', 'Monocytes': '0.0', 'Macrophages': '6.0', 'Hofbauer cells': '4.3', 'Kupffer cells': '1.0', 'Dendritic cells': '5.9', 'Langerhans cells': '0.304', 'Erythroid cells': '0.036', 'Adipocytes (Subcutaneous)': '-0.081', 'Adipocytes (Visceral)': '-0.209', 'Breast glandular cells (progenitors)': '0.538', 'Adipocytes (Breast)': '-0.689', 'Colon enterocytes': '0.790', 'Colon enteroendocrine cells': '0.112', 'Enteric glia cells': '-0.048', 'Mitotic cells (Colon)': '0.299', 'Mitotic cells (Heart)': '0.120', 'Podocytes': '-0.118', 'Ascending Loop of Henle cells': '0.475', 'Intercalated cells': '0.212', 'Cholangiocyte': '0.090', 'NK-cells (Liver)': '-0.005', 'Respiratory ciliated cells': '-0.012', 'Mitotic cells (Lung)': '0.071', 'NK-cells (Lung)': '-0.266', 'B-cells (Lung)': '-0.296', 'Alpha cells': '0.270', 'Beta cells': '0.152', 'Prostate glandular cells': '0.764', 'Prostate basal glandular cells': '0.540', 'Urothelial cells': '0.205', 'Keratinocyte (other)': '0.510', 'Keratinocyte (granular)': '0.055', 'Hair cortex cells': '0.080', 'Inner root sheath cells': '0.131', 'Outer root sheath cells': '0.175', 'Sebaceous gland cells': '0.156', 'Eccrine sweat gland cells': '-0.207', 'Adipocytes (Skin)': '-0.244', 'Mitotic cells (Skin)': '0.442', 'Parietal cells': '0.654', 'Chief cells': '0.649', 'Gastric mucous cells': '0.781', 'Gastric enteroendocrine cells': '0.590', 'Mitotic cells (Stomach)': '0.445', 'Parafollicular cells': '0.173', 'Thyroid glandular cells': '0.865', 'Mitotic cells (Thyroid)': '-0.081', 'Adrenal cortex cells': '0.051', 'Adrenal medulla cells': '0.087', 'Mitotic cells (Adrenal gland)': '0.072', 'Minor salivary glandular cells': '0.371', 'Minor salivary gland ductal cells': '-0.142', 'Minor salivary gland basal cells': '0.582', 'Mitotic cells (Minor salivary gland)': '0.567', 'Adipocytes (Minor salivary gland)': '0.050', 'Somatotropes': '0.121', 'Lactotropes': '0.322', 'Gonadotropes': '0.330', 'Corticotropes': '0.180', 'Thyrotropes': '0.496', 'Undifferentiated cells (Pituitary gland)': '-0.108', 'Mitotic cells (Spleen)': '-0.228', 'Platelets': '-0.050', 'Erythrocytes': '-0.158', 'Hematopoietic stem cells': '-0.211', 'B-cells (Spleen)': '0.266', 'NK-cells (Spleen)': '0.309', 'Amygdala excitatory': '1.0', 'Cerebellar inhibitory': '0.9', 'Cge interneuron': '0.7', 'Deep-layer corticothalamic and 6b': '1.5', 'Deep-layer intratelencephalic': '0.7', 'Deep-layer near-projecting': '0.7', 'Eccentric medium spiny neuron': '0.6', 'Hippocampal ca1-3': '1.9', 'Hippocampal ca4': '1.2', 'Hippocampal dentate gyrus': '1.1', 'Lamp5-lhx6 and chandelier': '0.5', 'Lower rhombic lip': '0.8', 'Mammillary body': '0.6', 'Medium spiny neuron': '0.7', 'Mge interneuron': '1.7', 'Midbrain-derived inhibitory': '0.7', 'Miscellaneous': '0.9', 'Splatter': '3.8', 'Thalamic excitatory': '0.5', 'Upper rhombic lip': '0.8', 'Upper-layer intratelencephalic': '0.6', 'Astrocyte': '4.4', 'Bergmann glia': '0.2', 'Central nervous system macrophage': '0.6', 'Choroid plexus epithelial cell': '52.1', 'Committed oligodendrocyte precursor': '41.5', 'Ependymal cell': '4.8', 'Oligodendrocyte': '53.1', 'Oligodendrocyte precursor cell': '2.4', 'Endothelial cell': '0.7', 'Pericyte': '0.3', 'Vascular associated smooth muscle cell': '0.0', 'Fibroblast': '17.4', 'Leukocyte': '1.1', 'Basophil': '0.0', 'Eosinophil': '0.0', 'Neutrophil': '0.0', 'Classical monocyte': '0.0', 'Non-classical monocyte': '0.0', 'Intermediate monocyte': '0.0', 'T-reg': '2.3', 'GdT-cell': '0.0', 'MAIT T-cell': '0.0', 'Memory CD4 T-cell': '0.0', 'Naive CD4 T-cell': '0.1', 'Memory CD8 T-cell': '0.2', 'Naive CD8 T-cell': '0.3', 'Memory B-cell': '0.0', 'Naive B-cell': '0.1', 'Plasmacytoid DC': '46.6', 'Myeloid DC': '8.5', 'NK-cell': '0.1', 'Total PBMC': '0.7', 'Vd2 gdTCR': '0.0', 'Memory CD4 T-cell Th1\\/Th17': '0.1', 'Memory CD4 T-cell Th17': '0.2', 'Memory CD4 T-cell Th2': '2.9', 'Non-Vd2 gdTCR': '0.1', 'Memory CD4 T-cell Th1': '0.3', 'Memory CD4 T-cell TFH': '0.5', 'Terminal effector memory CD4 T-cell': '0.0', 'Central memory CD8 T-cell': '4.8', 'Effector memory CD8 T-cell': '0.0', 'Terminal effector memory CD8 T-cell': '0.6', 'Non-switched memory B-cell': '0.0', 'Plasmablast': '3.3', 'Switched memory B-cell': '0.0', 'Exhausted memory B-cell': '0.7', 'Progenitor cell': '2.3', 'Memory T-reg': '1.3', 'Naive CD4 T-cell activated': '0.3', 'Naive CD8 T-cell activated': '0.6', 'Naive T-reg': '0.1'} | 1O6S, 2O72, 2OMT, 2OMU, 2OMV, 2OMX, 2OMY, 2OMZ, 3FF7, 3FF8, 3L6X, 3L6Y, 4ZT1, 4ZTE, 6CXY, 6OLE, 6OLF, 6OLG, 6VEL, 7STZ, 8H62 | {'Adipose Tissue': 1.2125261088039867, 'Adrenal Gland': 0.1914223992248062, 'Bladder': 39.2033519047619, 'Blood': 1.340954264800861, 'Blood Vessel': 0.3121561692883895, 'Brain': 0.8550442199091597, 'Breast': 38.54918344226579, 'Cervix Uteri': 23.539115789473684, 'Colon': 43.41292142490372, 'Esophagus': 53.97513367404844, 'Fallopian Tube': 14.900277777777776, 'Heart': 0.119140469221835, 'Kidney': 25.040449438202245, 'Liver': 26.60802654867257, 'Lung': 35.447986366782004, 'Muscle': 0.1378936151930261, 'Nerve': 17.518468982229404, 'Ovary': 3.6515122222222223, 'Pancreas': 56.89676829268293, 'Pituitary': 24.68741660777385, 'Prostate': 61.279967346938776, 'Salivary Gland': 92.01685185185184, 'Skin': 79.77571720232172, 'Small Intestine': 71.7519320855615, 'Spleen': 10.061029045643156, 'Stomach': 58.07813805013927, 'Testis': 0.8144204986149585, 'Thyroid': 135.176797856049, 'Uterus': 1.442593943661972, 'Vagina': 86.52345512820513} | CDC20 | MAQFAFESDLHSLLQLDAPIPNAPPARWQRKAKEAAGPAPSPMRAANRSHSAGRTPGRTPGKSSSKVQTTPSKPGGDRYIPHRSAAQMEVASFLLSKENQPENSQTPTKKEHQKAWALNLNGFDVEEAKILRLSGKPQNAPEGYQNRLKVLYSQKATPGSSRKTCRYIPSLPDRILDAPEIRNDYYLNLVDWSSGNVLAVALDNSVYLWSASSGDILQLLQMEQPGEYISSVAWIKEGNYLAVGTSSAEVQLWDVQQQKRLRNMTSHSARVGSLSWNSYILSSGSRSGHIHHHDVRVAEHHVATLSGHSQEVCGLRWAPDGRHLASGGNDNLVNVWPSAPGEGGWVPLQTFTQHQGAVKAVAWCPWQSNVLATGGGTSDRHIRIWNVCSGACLSAVDAHSQVCSILWSPHYKELISGHGFAQNQLVIWKYPTMAKVAELKGHTSRVLSLTMSPDGATVASAAADETLRLWRCFELDPARRREREKASAAKSSLIHQGIR | Homo sapiens | Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, Chromosome, centromere, kinetochore, Cytoplasm, cytoskeleton, spindle pole | Tissue enhanced (bone marrow, lymphoid tissue, testis) | {'Ciliated cells': '10.7', 'Basal respiratory cells': '18.1', 'Club cells': '5.1', 'Ionocytes': '13.6', 'Mucus glandular cells': '3.0', 'Serous glandular cells': '7.7', 'Gastric mucus-secreting cells': '13.0', 'Proximal enterocytes': '2.5', 'Paneth cells': '1.5', 'Distal enterocytes': '3.3', 'Intestinal goblet cells': '13.7', 'Exocrine glandular cells': '-0.309', 'Basal prostatic cells': '0.5', 'Prostatic glandular cells': '0.0', 'Breast glandular cells': '0.389', 'Breast myoepithelial cells': '0.180', 'Glandular and luminal cells': '4.8', 'Secretory cells': '0.8', 'Basal keratinocytes': '23.5', 'Suprabasal keratinocytes': '12.1', 'Basal squamous epithelial cells': '16.6', 'Squamous epithelial cells': '45.2', 'Alveolar cells type 1': '-0.269', 'Alveolar cells type 2': '0.212', 'Salivary duct cells': '5.7', 'Ductal cells': '0.460', 'Hepatocytes': '0.320', 'Cholangiocytes': '1.9', 'Proximal tubular cells': '0.491', 'Distal tubular cells': '3.1', 'Collecting duct cells': '0.0', 'Mesothelial cells': '-0.109', 'Sertoli cells': '-0.447', 'Granulosa cells': '6.6', 'Enteroendocrine cells': '5.1', 'Pancreatic endocrine cells': '30.6', 'Leydig cells': '-0.493', 'Excitatory neurons': '0.1', 'Inhibitory neurons': '0.0', 'Cone photoreceptor cells': '0.0', 'Rod photoreceptor cells': '2.8', 'Bipolar cells': '0.4', 'Horizontal cells': '0.0', 'Astrocytes': '0.0', 'Oligodendrocyte precursor cells': '0.0', 'Oligodendrocytes': '1.5', 'Microglial cells': '0.0', 'Muller glia cells': '0.0', 'Schwann cells': '0.072', 'Spermatogonia': '-0.113', 'Spermatocytes': '0.279', 'Early spermatids': '0.741', 'Late spermatids': '0.592', 'Oocytes': '12.5', 'Cytotrophoblasts': '73.3', 'Syncytiotrophoblasts': '11.3', 'Extravillous trophoblasts': '148.6', 'Endothelial cells': '3.3', 'Lymphatic endothelial cells': '0.3', 'Cardiomyocytes': '0.471', 'Skeletal myocytes': '-0.141', 'Smooth muscle cells': '3.1', 'Adipocytes': '2.0', 'Melanocytes': '0.465', 'Fibroblasts': '9.2', 'Peritubular cells': '-0.419', 'Endometrial stromal cells': '1.7', 'Ovarian stromal cells': '0.4', 'Undifferentiated cells': '76.0', 'T-cells': '4.6', 'B-cells': '1.6', 'Plasma cells': '49.4', 'Nk-cells': '1.2', 'Granulocytes': '2.0', 'Monocytes': '0.2', 'Macrophages': '7.0', 'Hofbauer cells': '29.9', 'Kupffer cells': '5.8', 'Dendritic cells': '0.4', 'Langerhans cells': '0.175', 'Erythroid cells': '0.139', 'Adipocytes (Subcutaneous)': '0.228', 'Adipocytes (Visceral)': '0.094', 'Breast glandular cells (progenitors)': '0.372', 'Adipocytes (Breast)': '-0.147', 'Colon enterocytes': '0.377', 'Colon enteroendocrine cells': '-0.181', 'Enteric glia cells': '-0.260', 'Mitotic cells (Colon)': '0.682', 'Mitotic cells (Heart)': '0.755', 'Podocytes': '-0.128', 'Ascending Loop of Henle cells': '0.116', 'Intercalated cells': '-0.141', 'Cholangiocyte': '0.317', 'NK-cells (Liver)': '-0.127', 'Respiratory ciliated cells': '0.052', 'Mitotic cells (Lung)': '0.870', 'NK-cells (Lung)': '-0.178', 'B-cells (Lung)': '-0.028', 'Alpha cells': '0.195', 'Beta cells': '0.079', 'Prostate glandular cells': '-0.077', 'Prostate basal glandular cells': '0.267', 'Urothelial cells': '0.231', 'Keratinocyte (other)': '0.296', 'Keratinocyte (granular)': '-0.055', 'Hair cortex cells': '0.020', 'Inner root sheath cells': '0.146', 'Outer root sheath cells': '0.145', 'Sebaceous gland cells': '0.172', 'Eccrine sweat gland cells': '-0.109', 'Adipocytes (Skin)': '-0.136', 'Mitotic cells (Skin)': '0.843', 'Parietal cells': '0.201', 'Chief cells': '0.163', 'Gastric mucous cells': '0.628', 'Gastric enteroendocrine cells': '0.253', 'Mitotic cells (Stomach)': '0.912', 'Parafollicular cells': '0.005', 'Thyroid glandular cells': '0.284', 'Mitotic cells (Thyroid)': '0.288', 'Adrenal cortex cells': '0.390', 'Adrenal medulla cells': '0.126', 'Mitotic cells (Adrenal gland)': '0.899', 'Minor salivary glandular cells': '0.070', 'Minor salivary gland ductal cells': '-0.179', 'Minor salivary gland basal cells': '0.716', 'Mitotic cells (Minor salivary gland)': '0.866', 'Adipocytes (Minor salivary gland)': '0.224', 'Somatotropes': '-0.263', 'Lactotropes': '-0.135', 'Gonadotropes': '0.036', 'Corticotropes': '-0.079', 'Thyrotropes': '-0.010', 'Undifferentiated cells (Pituitary gland)': '0.345', 'Mitotic cells (Spleen)': '0.905', 'Platelets': '0.216', 'Erythrocytes': '0.290', 'Hematopoietic stem cells': '0.378', 'B-cells (Spleen)': '-0.103', 'NK-cells (Spleen)': '-0.290', 'Amygdala excitatory': '0.1', 'Cerebellar inhibitory': '0.1', 'Cge interneuron': '0.1', 'Deep-layer corticothalamic and 6b': '0.1', 'Deep-layer intratelencephalic': '0.1', 'Deep-layer near-projecting': '0.0', 'Eccentric medium spiny neuron': '0.0', 'Hippocampal ca1-3': '0.1', 'Hippocampal ca4': '0.1', 'Hippocampal dentate gyrus': '0.1', 'Lamp5-lhx6 and chandelier': '0.1', 'Lower rhombic lip': '0.1', 'Mammillary body': '0.1', 'Medium spiny neuron': '0.1', 'Mge interneuron': '0.2', 'Midbrain-derived inhibitory': '0.1', 'Miscellaneous': '0.1', 'Splatter': '0.1', 'Thalamic excitatory': '0.0', 'Upper rhombic lip': '0.3', 'Upper-layer intratelencephalic': '0.2', 'Astrocyte': '0.1', 'Bergmann glia': '0.0', 'Central nervous system macrophage': '0.2', 'Choroid plexus epithelial cell': '0.7', 'Committed oligodendrocyte precursor': '0.6', 'Ependymal cell': '0.2', 'Oligodendrocyte': '2.7', 'Oligodendrocyte precursor cell': '0.1', 'Endothelial cell': '0.1', 'Pericyte': '0.2', 'Vascular associated smooth muscle cell': '0.0', 'Fibroblast': '0.1', 'Leukocyte': '0.1', 'Basophil': '0.1', 'Eosinophil': '0.0', 'Neutrophil': '0.0', 'Classical monocyte': '0.5', 'Non-classical monocyte': '0.4', 'Intermediate monocyte': '0.3', 'T-reg': '8.6', 'GdT-cell': '0.3', 'MAIT T-cell': '0.0', 'Memory CD4 T-cell': '3.2', 'Naive CD4 T-cell': '0.9', 'Memory CD8 T-cell': '3.5', 'Naive CD8 T-cell': '1.5', 'Memory B-cell': '4.2', 'Naive B-cell': '0.4', 'Plasmacytoid DC': '1.0', 'Myeloid DC': '1.9', 'NK-cell': '1.7', 'Total PBMC': '7.3', 'Vd2 gdTCR': '0.7', 'Memory CD4 T-cell Th1\\/Th17': '1.0', 'Memory CD4 T-cell Th17': '1.1', 'Memory CD4 T-cell Th2': '1.4', 'Non-Vd2 gdTCR': '0.0', 'Memory CD4 T-cell Th1': '2.1', 'Memory CD4 T-cell TFH': '0.6', 'Terminal effector memory CD4 T-cell': '0.0', 'Central memory CD8 T-cell': '2.4', 'Effector memory CD8 T-cell': '11.2', 'Terminal effector memory CD8 T-cell': '1.0', 'Non-switched memory B-cell': '1.7', 'Plasmablast': '122.6', 'Switched memory B-cell': '6.5', 'Exhausted memory B-cell': '14.6', 'Progenitor cell': '1.7', 'Memory T-reg': '5.5', 'Naive CD4 T-cell activated': '0.6', 'Naive CD8 T-cell activated': '1.0', 'Naive T-reg': '0.8'} | 4GGA, 4GGC, 4GGD, 4N14, 5G04, 5KHR, 5KHU, 5LCW, 6F0X, 6Q6G, 6Q6H | {'Adipose Tissue': 2.2786306644518275, 'Adrenal Gland': 2.048905968992248, 'Bladder': 1.9396333333333335, 'Blood': 29.0616601722282, 'Blood Vessel': 1.144201647940075, 'Brain': 0.7357121271763816, 'Breast': 2.6461001960784314, 'Cervix Uteri': 3.253421052631579, 'Colon': 7.793533645699615, 'Esophagus': 14.337347557093423, 'Fallopian Tube': 1.1193666666666668, 'Heart': 0.671262768873403, 'Kidney': 2.6050022471910115, 'Liver': 1.3700479203539824, 'Lung': 4.880240830449827, 'Muscle': 0.2785133748443337, 'Nerve': 2.5705977382875607, 'Ovary': 1.4988983333333332, 'Pancreas': 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complex composed of at least E-cadherin/CDH1, beta-catenin/CTNNB1 or gamma-catenin/JUP, and potentially alpha-catenin/CTNNA1. Forms a ternary complex composed of ADAM10, CADH1 and EPHA4, | null | null | KLRG1, SPEF1, DLGAP5, AJAP1, RAPGEF2, RAB8B, PIP5K1C, PKP2, TRPV4, CTNNB1, CAV1, DDR1, TBC1D2, CTNNA1, JUP, CTNND1, PSEN1, LIMA1, CDH1, JUP, ADAM10, CADH1 , EPHA4, | null | null | null | null | Homodimer | null | 79.91949 | 0.474025 | 84.601884 | 0.437455 | 1,590 |
P12830 | Q13309 | null | degron_data | CDH1 | MGPWSRSLSALLLLLQVSSWLCQEPEPCHPGFDAESYTFTVPRRHLERGRVLGRVNFEDCTGRQRTAYFSLDTRFKVGTDGVITVKRPLRFHNPQIHFLVYAWDSTYRKFSTKVTLNTVGHHHRPPPHQASVSGIQAELLTFPNSSPGLRRQKRDWVIPPISCPENEKGPFPKNLVQIKSNKDKEGKVFYSITGQGADTPPVGVFIIERETGWLKVTEPLDRERIATYTLFSHAVSSNGNAVEDPMEILITVTDQNDNKPEFTQEVFKGSVMEGALPGTSVMEVTATDADDDVNTYNAAIAYTILSQDPELPDKNMFTINRNTGVISVVTTGLDRESFPTYTLVVQAADLQGEGLSTTATAVITVTDTNDNPPIFNPTTYKGQVPENEANVVITTLKVTDADAPNTPAWEAVYTILNDDGGQFVVTTNPVNNDGILKTAKGLDFEAKQQYILHVAVTNVVPFEVSLTTSTATVTVDVLDVNEAPIFVPPEKRVEVSEDFGVGQEITSYTAQEPDTFMEQKITYRIWRDTANWLEINPDTGAISTRAELDREDFEHVKNSTYTALIIATDNGSPVATGTGTLLLILSDVNDNAPIPEPRTIFFCERNPKPQVINIIDADLPPNTSPFTAELTHGASANWTIQYNDPTQESIILKPKMALEVGDYKINLKLMDNQNKDQVTTLEVSVCDCEGAAGVCRKAQPVEAGLQIPAILGILGGILALLILILLLLLFLRRRAVVKEPLLPPEDDTRDNVYYYDEEGGGEEDQDFDLSQLHRGLDARPEVTRNDVAPTLMSVPRYLPRPANPDEIGNFIDENLKAADTDPTAPPYDSLLVFDYEGSGSEAASLSSLNSSESDKDQDYDYLNEWGNRFKKLADMYGGGEDD | Homo sapiens | Cell junction, adherens junction, Cell membrane, Endosome, Golgi apparatus, trans-Golgi network, Cytoplasm, Cell junction, desmosome | Tissue enhanced (parathyroid) | {'Ciliated cells': '119.1', 'Basal respiratory cells': '71.1', 'Club cells': '97.3', 'Ionocytes': '81.0', 'Mucus glandular cells': '155.0', 'Serous glandular cells': '67.8', 'Gastric mucus-secreting cells': '133.2', 'Proximal enterocytes': '140.9', 'Paneth cells': '125.1', 'Distal enterocytes': '307.5', 'Intestinal goblet cells': '173.5', 'Exocrine glandular cells': '-0.605', 'Basal prostatic cells': '68.3', 'Prostatic glandular cells': '186.7', 'Breast glandular cells': '0.773', 'Breast myoepithelial cells': '0.700', 'Glandular and luminal cells': '313.0', 'Secretory cells': '82.3', 'Basal keratinocytes': '102.5', 'Suprabasal keratinocytes': '162.6', 'Basal squamous epithelial cells': '51.0', 'Squamous epithelial cells': '106.9', 'Alveolar cells type 1': '0.437', 'Alveolar cells type 2': '0.706', 'Salivary duct cells': '95.9', 'Ductal cells': '0.541', 'Hepatocytes': '0.600', 'Cholangiocytes': '129.7', 'Proximal tubular cells': '0.042', 'Distal tubular cells': '0.0', 'Collecting duct cells': '143.9', 'Mesothelial cells': '0.799', 'Sertoli cells': '0.252', 'Granulosa cells': '12.9', 'Enteroendocrine cells': '92.4', 'Pancreatic endocrine cells': '78.1', 'Leydig cells': '0.264', 'Excitatory neurons': '0.7', 'Inhibitory neurons': '1.3', 'Cone photoreceptor cells': '0.0', 'Rod photoreceptor cells': '0.0', 'Bipolar cells': '0.2', 'Horizontal cells': '0.6', 'Astrocytes': '0.6', 'Oligodendrocyte precursor cells': '0.5', 'Oligodendrocytes': '29.9', 'Microglial cells': '0.9', 'Muller glia cells': '0.1', 'Schwann cells': '0.131', 'Spermatogonia': '0.392', 'Spermatocytes': '0.193', 'Early spermatids': '-0.217', 'Late spermatids': '-0.290', 'Oocytes': '16.9', 'Cytotrophoblasts': '119.2', 'Syncytiotrophoblasts': '45.0', 'Extravillous trophoblasts': '24.9', 'Endothelial cells': '6.1', 'Lymphatic endothelial cells': '0.4', 'Cardiomyocytes': '0.135', 'Skeletal myocytes': '0.107', 'Smooth muscle cells': '5.8', 'Adipocytes': '2.1', 'Melanocytes': '0.335', 'Fibroblasts': '6.5', 'Peritubular cells': '0.210', 'Endometrial stromal cells': '27.7', 'Ovarian stromal cells': '0.7', 'Undifferentiated cells': '101.6', 'T-cells': '2.9', 'B-cells': '4.4', 'Plasma cells': '6.1', 'Nk-cells': '0.0', 'Granulocytes': '8.4', 'Monocytes': '0.0', 'Macrophages': '6.0', 'Hofbauer cells': '4.3', 'Kupffer cells': '1.0', 'Dendritic cells': '5.9', 'Langerhans cells': '0.304', 'Erythroid cells': '0.036', 'Adipocytes (Subcutaneous)': '-0.081', 'Adipocytes (Visceral)': '-0.209', 'Breast glandular cells (progenitors)': '0.538', 'Adipocytes (Breast)': '-0.689', 'Colon enterocytes': '0.790', 'Colon enteroendocrine cells': '0.112', 'Enteric glia cells': '-0.048', 'Mitotic cells (Colon)': '0.299', 'Mitotic cells (Heart)': '0.120', 'Podocytes': '-0.118', 'Ascending Loop of Henle cells': '0.475', 'Intercalated cells': '0.212', 'Cholangiocyte': '0.090', 'NK-cells (Liver)': '-0.005', 'Respiratory ciliated cells': '-0.012', 'Mitotic cells (Lung)': '0.071', 'NK-cells (Lung)': '-0.266', 'B-cells (Lung)': '-0.296', 'Alpha cells': '0.270', 'Beta cells': '0.152', 'Prostate glandular cells': '0.764', 'Prostate basal glandular cells': '0.540', 'Urothelial cells': '0.205', 'Keratinocyte (other)': '0.510', 'Keratinocyte (granular)': '0.055', 'Hair cortex cells': '0.080', 'Inner root sheath cells': '0.131', 'Outer root sheath cells': '0.175', 'Sebaceous gland cells': '0.156', 'Eccrine sweat gland cells': '-0.207', 'Adipocytes (Skin)': '-0.244', 'Mitotic cells (Skin)': '0.442', 'Parietal cells': '0.654', 'Chief cells': '0.649', 'Gastric mucous cells': '0.781', 'Gastric enteroendocrine cells': '0.590', 'Mitotic cells (Stomach)': '0.445', 'Parafollicular cells': '0.173', 'Thyroid glandular cells': '0.865', 'Mitotic cells (Thyroid)': '-0.081', 'Adrenal cortex cells': '0.051', 'Adrenal medulla cells': '0.087', 'Mitotic cells (Adrenal gland)': '0.072', 'Minor salivary glandular cells': '0.371', 'Minor salivary gland ductal cells': '-0.142', 'Minor salivary gland basal cells': '0.582', 'Mitotic cells (Minor salivary gland)': '0.567', 'Adipocytes (Minor salivary gland)': '0.050', 'Somatotropes': '0.121', 'Lactotropes': '0.322', 'Gonadotropes': '0.330', 'Corticotropes': '0.180', 'Thyrotropes': '0.496', 'Undifferentiated cells (Pituitary gland)': '-0.108', 'Mitotic cells (Spleen)': '-0.228', 'Platelets': '-0.050', 'Erythrocytes': '-0.158', 'Hematopoietic stem cells': '-0.211', 'B-cells (Spleen)': '0.266', 'NK-cells (Spleen)': '0.309', 'Amygdala excitatory': '1.0', 'Cerebellar inhibitory': '0.9', 'Cge interneuron': '0.7', 'Deep-layer corticothalamic and 6b': '1.5', 'Deep-layer intratelencephalic': '0.7', 'Deep-layer near-projecting': '0.7', 'Eccentric medium spiny neuron': '0.6', 'Hippocampal ca1-3': '1.9', 'Hippocampal ca4': '1.2', 'Hippocampal dentate gyrus': '1.1', 'Lamp5-lhx6 and chandelier': '0.5', 'Lower rhombic lip': '0.8', 'Mammillary body': '0.6', 'Medium spiny neuron': '0.7', 'Mge interneuron': '1.7', 'Midbrain-derived inhibitory': '0.7', 'Miscellaneous': '0.9', 'Splatter': '3.8', 'Thalamic excitatory': '0.5', 'Upper rhombic lip': '0.8', 'Upper-layer intratelencephalic': '0.6', 'Astrocyte': '4.4', 'Bergmann glia': '0.2', 'Central nervous system macrophage': '0.6', 'Choroid plexus epithelial cell': '52.1', 'Committed oligodendrocyte precursor': '41.5', 'Ependymal cell': '4.8', 'Oligodendrocyte': '53.1', 'Oligodendrocyte precursor cell': '2.4', 'Endothelial cell': '0.7', 'Pericyte': '0.3', 'Vascular associated smooth muscle cell': '0.0', 'Fibroblast': '17.4', 'Leukocyte': '1.1', 'Basophil': '0.0', 'Eosinophil': '0.0', 'Neutrophil': '0.0', 'Classical monocyte': '0.0', 'Non-classical monocyte': '0.0', 'Intermediate monocyte': '0.0', 'T-reg': '2.3', 'GdT-cell': '0.0', 'MAIT T-cell': '0.0', 'Memory CD4 T-cell': '0.0', 'Naive CD4 T-cell': '0.1', 'Memory CD8 T-cell': '0.2', 'Naive CD8 T-cell': '0.3', 'Memory B-cell': '0.0', 'Naive B-cell': '0.1', 'Plasmacytoid DC': '46.6', 'Myeloid DC': '8.5', 'NK-cell': '0.1', 'Total PBMC': '0.7', 'Vd2 gdTCR': '0.0', 'Memory CD4 T-cell Th1\\/Th17': '0.1', 'Memory CD4 T-cell Th17': '0.2', 'Memory CD4 T-cell Th2': '2.9', 'Non-Vd2 gdTCR': '0.1', 'Memory CD4 T-cell Th1': '0.3', 'Memory CD4 T-cell TFH': '0.5', 'Terminal effector memory CD4 T-cell': '0.0', 'Central memory CD8 T-cell': '4.8', 'Effector memory CD8 T-cell': '0.0', 'Terminal effector memory CD8 T-cell': '0.6', 'Non-switched memory B-cell': '0.0', 'Plasmablast': '3.3', 'Switched memory B-cell': '0.0', 'Exhausted memory B-cell': '0.7', 'Progenitor cell': '2.3', 'Memory T-reg': '1.3', 'Naive CD4 T-cell activated': '0.3', 'Naive CD8 T-cell activated': '0.6', 'Naive T-reg': '0.1'} | 1O6S, 2O72, 2OMT, 2OMU, 2OMV, 2OMX, 2OMY, 2OMZ, 3FF7, 3FF8, 3L6X, 3L6Y, 4ZT1, 4ZTE, 6CXY, 6OLE, 6OLF, 6OLG, 6VEL, 7STZ, 8H62 | {'Adipose Tissue': 1.2125261088039867, 'Adrenal Gland': 0.1914223992248062, 'Bladder': 39.2033519047619, 'Blood': 1.340954264800861, 'Blood Vessel': 0.3121561692883895, 'Brain': 0.8550442199091597, 'Breast': 38.54918344226579, 'Cervix Uteri': 23.539115789473684, 'Colon': 43.41292142490372, 'Esophagus': 53.97513367404844, 'Fallopian Tube': 14.900277777777776, 'Heart': 0.119140469221835, 'Kidney': 25.040449438202245, 'Liver': 26.60802654867257, 'Lung': 35.447986366782004, 'Muscle': 0.1378936151930261, 'Nerve': 17.518468982229404, 'Ovary': 3.6515122222222223, 'Pancreas': 56.89676829268293, 'Pituitary': 24.68741660777385, 'Prostate': 61.279967346938776, 'Salivary Gland': 92.01685185185184, 'Skin': 79.77571720232172, 'Small Intestine': 71.7519320855615, 'Spleen': 10.061029045643156, 'Stomach': 58.07813805013927, 'Testis': 0.8144204986149585, 'Thyroid': 135.176797856049, 'Uterus': 1.442593943661972, 'Vagina': 86.52345512820513} | SKP2 | MHRKHLQEIPDLSSNVATSFTWGWDSSKTSELLSGMGVSALEKEEPDSENIPQELLSNLGHPESPPRKRLKSKGSDKDFVIVRRPKLNRENFPGVSWDSLPDELLLGIFSCLCLPELLKVSGVCKRWYRLASDESLWQTLDLTGKNLHPDVTGRLLSQGVIAFRCPRSFMDQPLAEHFSPFRVQHMDLSNSVIEVSTLHGILSQCSKLQNLSLEGLRLSDPIVNTLAKNSNLVRLNLSGCSGFSEFALQTLLSSCSRLDELNLSWCFDFTEKHVQVAVAHVSETITQLNLSGYRKNLQKSDLSTLVRRCPNLVHLDLSDSVMLKNDCFQEFFQLNYLQHLSLSRCYDIIPETLLELGEIPTLKTLQVFGIVPDGTLQLLKEALPHLQINCSHFTTIARPTIGNKKNQEIWGIKCRLTLQKPSCL | Homo sapiens | Cytoplasm, Nucleus | Tissue enhanced (placenta) | {'Ciliated cells': '5.4', 'Basal respiratory cells': '6.6', 'Club cells': '3.4', 'Ionocytes': '2.9', 'Mucus glandular cells': '2.5', 'Serous glandular cells': '6.3', 'Gastric mucus-secreting cells': '7.7', 'Proximal enterocytes': '3.5', 'Paneth cells': '4.2', 'Distal enterocytes': '2.0', 'Intestinal goblet cells': '5.2', 'Exocrine glandular cells': '-0.448', 'Basal prostatic cells': '3.7', 'Prostatic glandular cells': '5.6', 'Breast glandular cells': '0.282', 'Breast myoepithelial cells': '0.316', 'Glandular and luminal cells': '2.6', 'Secretory cells': '3.2', 'Basal keratinocytes': '8.0', 'Suprabasal keratinocytes': '5.7', 'Basal squamous epithelial cells': '14.8', 'Squamous epithelial cells': '19.7', 'Alveolar cells type 1': '-0.120', 'Alveolar cells type 2': '-0.162', 'Salivary duct cells': '3.9', 'Ductal cells': '0.507', 'Hepatocytes': '0.683', 'Cholangiocytes': '1.9', 'Proximal tubular cells': '0.096', 'Distal tubular cells': '0.0', 'Collecting duct cells': '3.9', 'Mesothelial cells': '0.485', 'Sertoli cells': '0.517', 'Granulosa cells': '8.9', 'Enteroendocrine cells': '4.1', 'Pancreatic endocrine cells': '1.7', 'Leydig cells': '0.631', 'Excitatory neurons': '21.7', 'Inhibitory neurons': '12.6', 'Cone photoreceptor cells': '8.5', 'Rod photoreceptor cells': '14.3', 'Bipolar cells': '11.4', 'Horizontal cells': '9.4', 'Astrocytes': '11.1', 'Oligodendrocyte precursor cells': '10.8', 'Oligodendrocytes': '27.5', 'Microglial cells': '11.6', 'Muller glia cells': '3.8', 'Schwann cells': '0.183', 'Spermatogonia': '0.620', 'Spermatocytes': '0.278', 'Early spermatids': '-0.325', 'Late spermatids': '-0.687', 'Oocytes': '35.3', 'Cytotrophoblasts': '143.4', 'Syncytiotrophoblasts': '70.7', 'Extravillous trophoblasts': '230.0', 'Endothelial cells': '4.7', 'Lymphatic endothelial cells': '5.5', 'Cardiomyocytes': '0.369', 'Skeletal myocytes': '0.067', 'Smooth muscle cells': '7.2', 'Adipocytes': '4.5', 'Melanocytes': '0.249', 'Fibroblasts': '8.0', 'Peritubular cells': '0.607', 'Endometrial stromal cells': '7.4', 'Ovarian stromal cells': '5.5', 'Undifferentiated cells': '15.8', 'T-cells': '6.8', 'B-cells': '7.9', 'Plasma cells': '12.6', 'Nk-cells': '9.4', 'Granulocytes': '7.0', 'Monocytes': '5.2', 'Macrophages': '6.2', 'Hofbauer cells': '21.8', 'Kupffer cells': '9.1', 'Dendritic cells': '5.2', 'Langerhans cells': '0.337', 'Erythroid cells': '0.015', 'Adipocytes (Subcutaneous)': '0.132', 'Adipocytes (Visceral)': '-0.220', 'Breast glandular cells (progenitors)': '0.188', 'Adipocytes (Breast)': '-0.192', 'Colon enterocytes': '-0.041', 'Colon enteroendocrine cells': '0.184', 'Enteric glia cells': '0.342', 'Mitotic cells (Colon)': '0.003', 'Mitotic cells (Heart)': '0.487', 'Podocytes': '-0.124', 'Ascending Loop of Henle cells': '0.475', 'Intercalated cells': '-0.015', 'Cholangiocyte': '-0.108', 'NK-cells (Liver)': '0.142', 'Respiratory ciliated cells': '0.079', 'Mitotic cells (Lung)': '0.252', 'NK-cells (Lung)': '0.034', 'B-cells (Lung)': '-0.002', 'Alpha cells': '0.440', 'Beta cells': '0.319', 'Prostate glandular cells': '-0.189', 'Prostate basal glandular cells': '0.201', 'Urothelial cells': '0.203', 'Keratinocyte (other)': '0.274', 'Keratinocyte (granular)': '-0.308', 'Hair cortex cells': '-0.030', 'Inner root sheath cells': '0.057', 'Outer root sheath cells': '0.265', 'Sebaceous gland cells': '0.266', 'Eccrine sweat gland cells': '-0.028', 'Adipocytes (Skin)': '-0.163', 'Mitotic cells (Skin)': '0.554', 'Parietal cells': '-0.361', 'Chief cells': '-0.294', 'Gastric mucous cells': '-0.120', 'Gastric enteroendocrine cells': '-0.099', 'Mitotic cells (Stomach)': '0.251', 'Parafollicular cells': '0.001', 'Thyroid glandular cells': '0.107', 'Mitotic cells (Thyroid)': '0.219', 'Adrenal cortex cells': '0.381', 'Adrenal medulla cells': '0.086', 'Mitotic cells (Adrenal gland)': '0.411', 'Minor salivary glandular cells': '-0.035', 'Minor salivary gland ductal cells': '-0.108', 'Minor salivary gland basal cells': '0.640', 'Mitotic cells (Minor salivary gland)': '0.673', 'Adipocytes (Minor salivary gland)': '0.168', 'Somatotropes': '0.027', 'Lactotropes': '0.300', 'Gonadotropes': '0.261', 'Corticotropes': '-0.069', 'Thyrotropes': '0.243', 'Undifferentiated cells (Pituitary gland)': '0.041', 'Mitotic cells (Spleen)': '0.095', 'Platelets': '-0.115', 'Erythrocytes': '-0.028', 'Hematopoietic stem cells': '-0.133', 'B-cells (Spleen)': '0.298', 'NK-cells (Spleen)': '0.278', 'Amygdala excitatory': '23.6', 'Cerebellar inhibitory': '17.5', 'Cge interneuron': '13.4', 'Deep-layer corticothalamic and 6b': '23.5', 'Deep-layer intratelencephalic': '31.2', 'Deep-layer near-projecting': '17.0', 'Eccentric medium spiny neuron': '16.5', 'Hippocampal ca1-3': '22.7', 'Hippocampal ca4': '19.7', 'Hippocampal dentate gyrus': '14.3', 'Lamp5-lhx6 and chandelier': '14.7', 'Lower rhombic lip': '13.5', 'Mammillary body': '21.8', 'Medium spiny neuron': '15.7', 'Mge interneuron': '18.2', 'Midbrain-derived inhibitory': '27.0', 'Miscellaneous': '29.5', 'Splatter': '15.9', 'Thalamic excitatory': '16.4', 'Upper rhombic lip': '20.4', 'Upper-layer intratelencephalic': '29.2', 'Astrocyte': '19.8', 'Bergmann glia': '11.8', 'Central nervous system macrophage': '40.2', 'Choroid plexus epithelial cell': '23.8', 'Committed oligodendrocyte precursor': '20.0', 'Ependymal cell': '20.8', 'Oligodendrocyte': '37.8', 'Oligodendrocyte precursor cell': '18.2', 'Endothelial cell': '13.4', 'Pericyte': '12.7', 'Vascular associated smooth muscle cell': '12.3', 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0.63, 0.56, 0.69, 0.24, 0.51, 0.27, 0.75, 0.54, 0.03, 0.18, 0.41, 0.46, 0.02, 0.43, 0.83, 0.26, 0.31, 0.04, 0.48, 0.39, 0.01, 0.14, 0.68, 0.16, 0.09, 0.83, 0.63, 0.39, 0.87, 0.27, 0.25, 0.44, 0.62, 0.01, 0.03, 0.34, 0.3, 0.36, 0.53, 0.03, 0.02, 0.45, 0.17, 0.0, 0.08, 0.06, 0.16, 0.35, 0.19, 0.49, 0.11, 0.31, 0.0, 0.11, 0.16, 0.01, 0.01, 0.23, 0.04, 0.01, 0.48, 0.16, 0.04, 0.0, 0.28, 0.01, 0.01, 0.11, 0.0, 0.06, 0.58, 0.0, 0.48, 0.0, 0.71, 0.49, 0.67, 0.28, 0.71, 0.4, 0.96, 0.18, 0.67, 0.73, 0.01, 0.48, 0.0, 0.3, 0.13, 0.0, 0.03, 0.02, 0.11, 0.53, 0.09, 0.47, 0.13, 0.4, 0.33, 0.52, 0.0, 0.0, 0.34, 0.29, 0.03, 0.0, 0.29, 0.27, 0.0, 0.48, 0.53, 0.0, 0.35, 0.05, 0.0, 0.0, 0.0, 0.12, 0.49, 0.03, 0.54, 0.02, 0.22, 0.31, 0.5, 0.0, 0.0, 0.43, 0.09, 0.01, 0.16, 0.49, 0.0, 0.37, 0.5, 0.0, 0.31, 0.29, 0.01, 0.0, 0.0, 0.11, 0.26, 0.0, 0.04, 0.26, 0.05, 0.26, 0.19, 0.73, 0.01, 0.01, 0.36, 0.46, 0.0, 0.03, 0.53, 0.27, 0.01, 0.56, 0.68, 0.0, 0.28, 0.11, 0.0, 0.0, 0.0, 0.03, 0.36, 0.02, 0.75, 0.42, 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E-cadherin/CDH1, beta-catenin/CTNNB1 or gamma-catenin/JUP, and potentially alpha-catenin/CTNNA1. Forms a ternary complex composed of ADAM10, CADH1 and EPHA4, | null | null | KLRG1, SPEF1, DLGAP5, AJAP1, RAPGEF2, RAB8B, PIP5K1C, PKP2, TRPV4, CTNNB1, CAV1, DDR1, TBC1D2, CTNNA1, JUP, CTNND1, PSEN1, LIMA1, CDH1, JUP, ADAM10, CADH1 , EPHA4, | null | null | null | null | Homodimer | null | 79.91949 | 0.474025 | 82.227665 | 0.401627 | 1,873 |
P12830 | Q13309-2 | null | degron_data | CDH1 | MGPWSRSLSALLLLLQVSSWLCQEPEPCHPGFDAESYTFTVPRRHLERGRVLGRVNFEDCTGRQRTAYFSLDTRFKVGTDGVITVKRPLRFHNPQIHFLVYAWDSTYRKFSTKVTLNTVGHHHRPPPHQASVSGIQAELLTFPNSSPGLRRQKRDWVIPPISCPENEKGPFPKNLVQIKSNKDKEGKVFYSITGQGADTPPVGVFIIERETGWLKVTEPLDRERIATYTLFSHAVSSNGNAVEDPMEILITVTDQNDNKPEFTQEVFKGSVMEGALPGTSVMEVTATDADDDVNTYNAAIAYTILSQDPELPDKNMFTINRNTGVISVVTTGLDRESFPTYTLVVQAADLQGEGLSTTATAVITVTDTNDNPPIFNPTTYKGQVPENEANVVITTLKVTDADAPNTPAWEAVYTILNDDGGQFVVTTNPVNNDGILKTAKGLDFEAKQQYILHVAVTNVVPFEVSLTTSTATVTVDVLDVNEAPIFVPPEKRVEVSEDFGVGQEITSYTAQEPDTFMEQKITYRIWRDTANWLEINPDTGAISTRAELDREDFEHVKNSTYTALIIATDNGSPVATGTGTLLLILSDVNDNAPIPEPRTIFFCERNPKPQVINIIDADLPPNTSPFTAELTHGASANWTIQYNDPTQESIILKPKMALEVGDYKINLKLMDNQNKDQVTTLEVSVCDCEGAAGVCRKAQPVEAGLQIPAILGILGGILALLILILLLLLFLRRRAVVKEPLLPPEDDTRDNVYYYDEEGGGEEDQDFDLSQLHRGLDARPEVTRNDVAPTLMSVPRYLPRPANPDEIGNFIDENLKAADTDPTAPPYDSLLVFDYEGSGSEAASLSSLNSSESDKDQDYDYLNEWGNRFKKLADMYGGGEDD | Homo sapiens | Cell junction, adherens junction, Cell membrane, Endosome, Golgi apparatus, trans-Golgi network, Cytoplasm, Cell junction, desmosome | Tissue enhanced (parathyroid) | {'Ciliated cells': '119.1', 'Basal respiratory cells': '71.1', 'Club cells': '97.3', 'Ionocytes': '81.0', 'Mucus glandular cells': '155.0', 'Serous glandular cells': '67.8', 'Gastric mucus-secreting cells': '133.2', 'Proximal enterocytes': '140.9', 'Paneth cells': '125.1', 'Distal enterocytes': '307.5', 'Intestinal goblet cells': '173.5', 'Exocrine glandular cells': '-0.605', 'Basal prostatic cells': '68.3', 'Prostatic glandular cells': '186.7', 'Breast glandular cells': '0.773', 'Breast myoepithelial cells': '0.700', 'Glandular and luminal cells': '313.0', 'Secretory cells': '82.3', 'Basal keratinocytes': '102.5', 'Suprabasal keratinocytes': '162.6', 'Basal squamous epithelial cells': '51.0', 'Squamous epithelial cells': '106.9', 'Alveolar cells type 1': '0.437', 'Alveolar cells type 2': '0.706', 'Salivary duct cells': '95.9', 'Ductal cells': '0.541', 'Hepatocytes': '0.600', 'Cholangiocytes': '129.7', 'Proximal tubular cells': '0.042', 'Distal tubular cells': '0.0', 'Collecting duct cells': '143.9', 'Mesothelial cells': '0.799', 'Sertoli cells': '0.252', 'Granulosa cells': '12.9', 'Enteroendocrine cells': '92.4', 'Pancreatic endocrine cells': '78.1', 'Leydig cells': '0.264', 'Excitatory neurons': '0.7', 'Inhibitory neurons': '1.3', 'Cone photoreceptor cells': '0.0', 'Rod photoreceptor cells': '0.0', 'Bipolar cells': '0.2', 'Horizontal cells': '0.6', 'Astrocytes': '0.6', 'Oligodendrocyte precursor cells': '0.5', 'Oligodendrocytes': '29.9', 'Microglial cells': '0.9', 'Muller glia cells': '0.1', 'Schwann cells': '0.131', 'Spermatogonia': '0.392', 'Spermatocytes': '0.193', 'Early spermatids': '-0.217', 'Late spermatids': '-0.290', 'Oocytes': '16.9', 'Cytotrophoblasts': '119.2', 'Syncytiotrophoblasts': '45.0', 'Extravillous trophoblasts': '24.9', 'Endothelial cells': '6.1', 'Lymphatic endothelial cells': '0.4', 'Cardiomyocytes': '0.135', 'Skeletal myocytes': '0.107', 'Smooth muscle cells': '5.8', 'Adipocytes': '2.1', 'Melanocytes': '0.335', 'Fibroblasts': '6.5', 'Peritubular cells': '0.210', 'Endometrial stromal cells': '27.7', 'Ovarian stromal cells': '0.7', 'Undifferentiated cells': '101.6', 'T-cells': '2.9', 'B-cells': '4.4', 'Plasma cells': '6.1', 'Nk-cells': '0.0', 'Granulocytes': '8.4', 'Monocytes': '0.0', 'Macrophages': '6.0', 'Hofbauer cells': '4.3', 'Kupffer cells': '1.0', 'Dendritic cells': '5.9', 'Langerhans cells': '0.304', 'Erythroid cells': '0.036', 'Adipocytes (Subcutaneous)': '-0.081', 'Adipocytes (Visceral)': '-0.209', 'Breast glandular cells (progenitors)': '0.538', 'Adipocytes (Breast)': '-0.689', 'Colon enterocytes': '0.790', 'Colon enteroendocrine cells': '0.112', 'Enteric glia cells': '-0.048', 'Mitotic cells (Colon)': '0.299', 'Mitotic cells (Heart)': '0.120', 'Podocytes': '-0.118', 'Ascending Loop of Henle cells': '0.475', 'Intercalated cells': '0.212', 'Cholangiocyte': '0.090', 'NK-cells (Liver)': '-0.005', 'Respiratory ciliated cells': '-0.012', 'Mitotic cells (Lung)': '0.071', 'NK-cells (Lung)': '-0.266', 'B-cells (Lung)': '-0.296', 'Alpha cells': '0.270', 'Beta cells': '0.152', 'Prostate glandular cells': '0.764', 'Prostate basal glandular cells': '0.540', 'Urothelial cells': '0.205', 'Keratinocyte (other)': '0.510', 'Keratinocyte (granular)': '0.055', 'Hair cortex cells': '0.080', 'Inner root sheath cells': '0.131', 'Outer root sheath cells': '0.175', 'Sebaceous gland cells': '0.156', 'Eccrine sweat gland cells': '-0.207', 'Adipocytes (Skin)': '-0.244', 'Mitotic cells (Skin)': '0.442', 'Parietal cells': '0.654', 'Chief cells': '0.649', 'Gastric mucous cells': '0.781', 'Gastric enteroendocrine cells': '0.590', 'Mitotic cells (Stomach)': '0.445', 'Parafollicular cells': '0.173', 'Thyroid glandular cells': '0.865', 'Mitotic cells (Thyroid)': '-0.081', 'Adrenal cortex cells': '0.051', 'Adrenal medulla cells': '0.087', 'Mitotic cells (Adrenal gland)': '0.072', 'Minor salivary glandular cells': '0.371', 'Minor salivary gland ductal cells': '-0.142', 'Minor salivary gland basal cells': '0.582', 'Mitotic cells (Minor salivary gland)': '0.567', 'Adipocytes (Minor salivary gland)': '0.050', 'Somatotropes': '0.121', 'Lactotropes': '0.322', 'Gonadotropes': '0.330', 'Corticotropes': '0.180', 'Thyrotropes': '0.496', 'Undifferentiated cells (Pituitary gland)': '-0.108', 'Mitotic cells (Spleen)': '-0.228', 'Platelets': '-0.050', 'Erythrocytes': '-0.158', 'Hematopoietic stem cells': '-0.211', 'B-cells (Spleen)': '0.266', 'NK-cells (Spleen)': '0.309', 'Amygdala excitatory': '1.0', 'Cerebellar inhibitory': '0.9', 'Cge interneuron': '0.7', 'Deep-layer corticothalamic and 6b': '1.5', 'Deep-layer intratelencephalic': '0.7', 'Deep-layer near-projecting': '0.7', 'Eccentric medium spiny neuron': '0.6', 'Hippocampal ca1-3': '1.9', 'Hippocampal ca4': '1.2', 'Hippocampal dentate gyrus': '1.1', 'Lamp5-lhx6 and chandelier': '0.5', 'Lower rhombic lip': '0.8', 'Mammillary body': '0.6', 'Medium spiny neuron': '0.7', 'Mge interneuron': '1.7', 'Midbrain-derived inhibitory': '0.7', 'Miscellaneous': '0.9', 'Splatter': '3.8', 'Thalamic excitatory': '0.5', 'Upper rhombic lip': '0.8', 'Upper-layer intratelencephalic': '0.6', 'Astrocyte': '4.4', 'Bergmann glia': '0.2', 'Central nervous system macrophage': '0.6', 'Choroid plexus epithelial cell': '52.1', 'Committed oligodendrocyte precursor': '41.5', 'Ependymal cell': '4.8', 'Oligodendrocyte': '53.1', 'Oligodendrocyte precursor cell': '2.4', 'Endothelial cell': '0.7', 'Pericyte': '0.3', 'Vascular associated smooth muscle cell': '0.0', 'Fibroblast': '17.4', 'Leukocyte': '1.1', 'Basophil': '0.0', 'Eosinophil': '0.0', 'Neutrophil': '0.0', 'Classical monocyte': '0.0', 'Non-classical monocyte': '0.0', 'Intermediate monocyte': '0.0', 'T-reg': '2.3', 'GdT-cell': '0.0', 'MAIT T-cell': '0.0', 'Memory CD4 T-cell': '0.0', 'Naive CD4 T-cell': '0.1', 'Memory CD8 T-cell': '0.2', 'Naive CD8 T-cell': '0.3', 'Memory B-cell': '0.0', 'Naive B-cell': '0.1', 'Plasmacytoid DC': '46.6', 'Myeloid DC': '8.5', 'NK-cell': '0.1', 'Total PBMC': '0.7', 'Vd2 gdTCR': '0.0', 'Memory CD4 T-cell Th1\\/Th17': '0.1', 'Memory CD4 T-cell Th17': '0.2', 'Memory CD4 T-cell Th2': '2.9', 'Non-Vd2 gdTCR': '0.1', 'Memory CD4 T-cell Th1': '0.3', 'Memory CD4 T-cell TFH': '0.5', 'Terminal effector memory CD4 T-cell': '0.0', 'Central memory CD8 T-cell': '4.8', 'Effector memory CD8 T-cell': '0.0', 'Terminal effector memory CD8 T-cell': '0.6', 'Non-switched memory B-cell': '0.0', 'Plasmablast': '3.3', 'Switched memory B-cell': '0.0', 'Exhausted memory B-cell': '0.7', 'Progenitor cell': '2.3', 'Memory T-reg': '1.3', 'Naive CD4 T-cell activated': '0.3', 'Naive CD8 T-cell activated': '0.6', 'Naive T-reg': '0.1'} | 1O6S, 2O72, 2OMT, 2OMU, 2OMV, 2OMX, 2OMY, 2OMZ, 3FF7, 3FF8, 3L6X, 3L6Y, 4ZT1, 4ZTE, 6CXY, 6OLE, 6OLF, 6OLG, 6VEL, 7STZ, 8H62 | {'Adipose Tissue': 1.2125261088039867, 'Adrenal Gland': 0.1914223992248062, 'Bladder': 39.2033519047619, 'Blood': 1.340954264800861, 'Blood Vessel': 0.3121561692883895, 'Brain': 0.8550442199091597, 'Breast': 38.54918344226579, 'Cervix Uteri': 23.539115789473684, 'Colon': 43.41292142490372, 'Esophagus': 53.97513367404844, 'Fallopian Tube': 14.900277777777776, 'Heart': 0.119140469221835, 'Kidney': 25.040449438202245, 'Liver': 26.60802654867257, 'Lung': 35.447986366782004, 'Muscle': 0.1378936151930261, 'Nerve': 17.518468982229404, 'Ovary': 3.6515122222222223, 'Pancreas': 56.89676829268293, 'Pituitary': 24.68741660777385, 'Prostate': 61.279967346938776, 'Salivary Gland': 92.01685185185184, 'Skin': 79.77571720232172, 'Small Intestine': 71.7519320855615, 'Spleen': 10.061029045643156, 'Stomach': 58.07813805013927, 'Testis': 0.8144204986149585, 'Thyroid': 135.176797856049, 'Uterus': 1.442593943661972, 'Vagina': 86.52345512820513} | SKP2 | MHRKHLQEIPDLSSNVATSFTWGWDSSKTSELLSGMGVSALEKEEPDSENIPQELLSNLGHPESPPRKRLKSKGSDKDFVIVRRPKLNRENFPGVSWDSLPDELLLGIFSCLCLPELLKVSGVCKRWYRLASDESLWQTLDLTGKNLHPDVTGRLLSQGVIAFRCPRSFMDQPLAEHFSPFRVQHMDLSNSVIEVSTLHGILSQCSKLQNLSLEGLRLSDPIVNTLAKNSNLVRLNLSGCSGFSEFALQTLLSSCSRLDELNLSWCFDFTEKHVQVAVAHVSETITQLNLSGYRKNLQKSDLSTLVRRCPNLVHLDLSDSVMLKNDCFQEFFQLNYLQHLSLSRCYDIIPETLLLVTRAGVRIRLDSDIGCPQTYRTSKLKSSHKLFCQHVRVICIFVCDFYFYRLVLKQ | Homo sapiens | null | Not found | {} | null | {'Adipose Tissue': 7.884296760797342, 'Adrenal Gland': 6.029375968992248, 'Bladder': 8.704190476190476, 'Blood': 6.908304413347686, 'Blood Vessel': 5.634626367041198, 'Brain': 5.270861279333838, 'Breast': 7.036501089324618, 'Cervix Uteri': 11.363368421052632, 'Colon': 6.723202824133504, 'Esophagus': 8.647209965397924, 'Fallopian Tube': 10.392666666666663, 'Heart': 1.978051800232288, 'Kidney': 2.9395595505617975, 'Liver': 7.151542477876106, 'Lung': 7.259957093425605, 'Muscle': 1.7041732254047322, 'Nerve': 11.215163166397415, 'Ovary': 10.0352, 'Pancreas': 2.847617987804878, 'Pituitary': 8.211869257950529, 'Prostate': 7.6942612244897965, 'Salivary Gland': 6.274617283950618, 'Skin': 14.034285793255943, 'Small Intestine': 8.87992513368984, 'Spleen': 10.67515767634855, 'Stomach': 4.871679944289694, 'Testis': 5.268631578947368, 'Thyroid': 7.199923430321593, 'Uterus': 11.76773943661972, 'Vagina': 11.179852564102564} | [39.93, 46.46, 52.9, 44.21, 41.4, 39.93, 35.91, 38.61, 36.44, 36.25, 34.86, 32.82, 32.01, 32.75, 31.69, 35.64, 36.35, 34.66, 33.32, 32.71, 35.01, 30.17, 37.05, 36.53, 48.19, 58.22, 64.94, 73.22, 78.33, 82.63, 85.79, 89.39, 87.89, 85.58, 83.93, 89.1, 89.27, 90.66, 87.86, 86.2, 82.97, 72.75, 73.3, 76.44, 82.38, 82.41, 79.49, 86.6, 76.32, 85.48, 88.69, 84.35, 87.75, 90.57, 88.72, 89.46, 87.48, 85.3, 81.72, 79.46, 77.26, 69.01, 67.1, 62.83, 67.71, 74.96, 82.95, 86.74, 86.35, 86.49, 84.6, 85.99, 85.64, 87.19, 89.23, 89.3, 90.62, 84.21, 85.42, 83.34, 84.28, 89.8, 89.78, 87.53, 87.64, 85.98, 81.31, 80.85, 78.74, 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Forms a ternary complex composed of ADAM10, CADH1 and EPHA4, | null | null | KLRG1, SPEF1, DLGAP5, AJAP1, RAPGEF2, RAB8B, PIP5K1C, PKP2, TRPV4, CTNNB1, CAV1, DDR1, TBC1D2, CTNNA1, JUP, CTNND1, PSEN1, LIMA1, CDH1, JUP, ADAM10, CADH1 , EPHA4, | null | null | null | null | Homodimer | null | 79.91949 | 0.474025 | null | null | 1,873 |
P12830 | Q14807 | null | degron_data | CDH1 | MGPWSRSLSALLLLLQVSSWLCQEPEPCHPGFDAESYTFTVPRRHLERGRVLGRVNFEDCTGRQRTAYFSLDTRFKVGTDGVITVKRPLRFHNPQIHFLVYAWDSTYRKFSTKVTLNTVGHHHRPPPHQASVSGIQAELLTFPNSSPGLRRQKRDWVIPPISCPENEKGPFPKNLVQIKSNKDKEGKVFYSITGQGADTPPVGVFIIERETGWLKVTEPLDRERIATYTLFSHAVSSNGNAVEDPMEILITVTDQNDNKPEFTQEVFKGSVMEGALPGTSVMEVTATDADDDVNTYNAAIAYTILSQDPELPDKNMFTINRNTGVISVVTTGLDRESFPTYTLVVQAADLQGEGLSTTATAVITVTDTNDNPPIFNPTTYKGQVPENEANVVITTLKVTDADAPNTPAWEAVYTILNDDGGQFVVTTNPVNNDGILKTAKGLDFEAKQQYILHVAVTNVVPFEVSLTTSTATVTVDVLDVNEAPIFVPPEKRVEVSEDFGVGQEITSYTAQEPDTFMEQKITYRIWRDTANWLEINPDTGAISTRAELDREDFEHVKNSTYTALIIATDNGSPVATGTGTLLLILSDVNDNAPIPEPRTIFFCERNPKPQVINIIDADLPPNTSPFTAELTHGASANWTIQYNDPTQESIILKPKMALEVGDYKINLKLMDNQNKDQVTTLEVSVCDCEGAAGVCRKAQPVEAGLQIPAILGILGGILALLILILLLLLFLRRRAVVKEPLLPPEDDTRDNVYYYDEEGGGEEDQDFDLSQLHRGLDARPEVTRNDVAPTLMSVPRYLPRPANPDEIGNFIDENLKAADTDPTAPPYDSLLVFDYEGSGSEAASLSSLNSSESDKDQDYDYLNEWGNRFKKLADMYGGGEDD | Homo sapiens | Cell junction, adherens junction, Cell membrane, Endosome, Golgi apparatus, trans-Golgi network, Cytoplasm, Cell junction, desmosome | Tissue enhanced (parathyroid) | {'Ciliated cells': '119.1', 'Basal respiratory cells': '71.1', 'Club cells': '97.3', 'Ionocytes': '81.0', 'Mucus glandular cells': '155.0', 'Serous glandular cells': '67.8', 'Gastric mucus-secreting cells': '133.2', 'Proximal enterocytes': '140.9', 'Paneth cells': '125.1', 'Distal enterocytes': '307.5', 'Intestinal goblet cells': '173.5', 'Exocrine glandular cells': '-0.605', 'Basal prostatic cells': '68.3', 'Prostatic glandular cells': '186.7', 'Breast glandular cells': '0.773', 'Breast myoepithelial cells': '0.700', 'Glandular and luminal cells': '313.0', 'Secretory cells': '82.3', 'Basal keratinocytes': '102.5', 'Suprabasal keratinocytes': '162.6', 'Basal squamous epithelial cells': '51.0', 'Squamous epithelial cells': '106.9', 'Alveolar cells type 1': '0.437', 'Alveolar cells type 2': '0.706', 'Salivary duct cells': '95.9', 'Ductal cells': '0.541', 'Hepatocytes': '0.600', 'Cholangiocytes': '129.7', 'Proximal tubular cells': '0.042', 'Distal tubular cells': '0.0', 'Collecting duct cells': '143.9', 'Mesothelial cells': '0.799', 'Sertoli cells': '0.252', 'Granulosa cells': '12.9', 'Enteroendocrine cells': '92.4', 'Pancreatic endocrine cells': '78.1', 'Leydig cells': '0.264', 'Excitatory neurons': '0.7', 'Inhibitory neurons': '1.3', 'Cone photoreceptor cells': '0.0', 'Rod photoreceptor cells': '0.0', 'Bipolar cells': '0.2', 'Horizontal cells': '0.6', 'Astrocytes': '0.6', 'Oligodendrocyte precursor cells': '0.5', 'Oligodendrocytes': '29.9', 'Microglial cells': '0.9', 'Muller glia cells': '0.1', 'Schwann cells': '0.131', 'Spermatogonia': '0.392', 'Spermatocytes': '0.193', 'Early spermatids': '-0.217', 'Late spermatids': '-0.290', 'Oocytes': '16.9', 'Cytotrophoblasts': '119.2', 'Syncytiotrophoblasts': '45.0', 'Extravillous trophoblasts': '24.9', 'Endothelial cells': '6.1', 'Lymphatic endothelial cells': '0.4', 'Cardiomyocytes': '0.135', 'Skeletal myocytes': '0.107', 'Smooth muscle cells': '5.8', 'Adipocytes': '2.1', 'Melanocytes': '0.335', 'Fibroblasts': '6.5', 'Peritubular cells': '0.210', 'Endometrial stromal cells': '27.7', 'Ovarian stromal cells': '0.7', 'Undifferentiated cells': '101.6', 'T-cells': '2.9', 'B-cells': '4.4', 'Plasma cells': '6.1', 'Nk-cells': '0.0', 'Granulocytes': '8.4', 'Monocytes': '0.0', 'Macrophages': '6.0', 'Hofbauer cells': '4.3', 'Kupffer cells': '1.0', 'Dendritic cells': '5.9', 'Langerhans cells': '0.304', 'Erythroid cells': '0.036', 'Adipocytes (Subcutaneous)': '-0.081', 'Adipocytes (Visceral)': '-0.209', 'Breast glandular cells (progenitors)': '0.538', 'Adipocytes (Breast)': '-0.689', 'Colon enterocytes': '0.790', 'Colon enteroendocrine cells': '0.112', 'Enteric glia cells': '-0.048', 'Mitotic cells (Colon)': '0.299', 'Mitotic cells (Heart)': '0.120', 'Podocytes': '-0.118', 'Ascending Loop of Henle cells': '0.475', 'Intercalated cells': '0.212', 'Cholangiocyte': '0.090', 'NK-cells (Liver)': '-0.005', 'Respiratory ciliated cells': '-0.012', 'Mitotic cells (Lung)': '0.071', 'NK-cells (Lung)': '-0.266', 'B-cells (Lung)': '-0.296', 'Alpha cells': '0.270', 'Beta cells': '0.152', 'Prostate glandular cells': '0.764', 'Prostate basal glandular cells': '0.540', 'Urothelial cells': '0.205', 'Keratinocyte (other)': '0.510', 'Keratinocyte (granular)': '0.055', 'Hair cortex cells': '0.080', 'Inner root sheath cells': '0.131', 'Outer root sheath cells': '0.175', 'Sebaceous gland cells': '0.156', 'Eccrine sweat gland cells': '-0.207', 'Adipocytes (Skin)': '-0.244', 'Mitotic cells (Skin)': '0.442', 'Parietal cells': '0.654', 'Chief cells': '0.649', 'Gastric mucous cells': '0.781', 'Gastric enteroendocrine cells': '0.590', 'Mitotic cells (Stomach)': '0.445', 'Parafollicular cells': '0.173', 'Thyroid glandular cells': '0.865', 'Mitotic cells (Thyroid)': '-0.081', 'Adrenal cortex cells': '0.051', 'Adrenal medulla cells': '0.087', 'Mitotic cells (Adrenal gland)': '0.072', 'Minor salivary glandular cells': '0.371', 'Minor salivary gland ductal cells': '-0.142', 'Minor salivary gland basal cells': '0.582', 'Mitotic cells (Minor salivary gland)': '0.567', 'Adipocytes (Minor salivary gland)': '0.050', 'Somatotropes': '0.121', 'Lactotropes': '0.322', 'Gonadotropes': '0.330', 'Corticotropes': '0.180', 'Thyrotropes': '0.496', 'Undifferentiated cells (Pituitary gland)': '-0.108', 'Mitotic cells (Spleen)': '-0.228', 'Platelets': '-0.050', 'Erythrocytes': '-0.158', 'Hematopoietic stem cells': '-0.211', 'B-cells (Spleen)': '0.266', 'NK-cells (Spleen)': '0.309', 'Amygdala excitatory': '1.0', 'Cerebellar inhibitory': '0.9', 'Cge interneuron': '0.7', 'Deep-layer corticothalamic and 6b': '1.5', 'Deep-layer intratelencephalic': '0.7', 'Deep-layer near-projecting': '0.7', 'Eccentric medium spiny neuron': '0.6', 'Hippocampal ca1-3': '1.9', 'Hippocampal ca4': '1.2', 'Hippocampal dentate gyrus': '1.1', 'Lamp5-lhx6 and chandelier': '0.5', 'Lower rhombic lip': '0.8', 'Mammillary body': '0.6', 'Medium spiny neuron': '0.7', 'Mge interneuron': '1.7', 'Midbrain-derived inhibitory': '0.7', 'Miscellaneous': '0.9', 'Splatter': '3.8', 'Thalamic excitatory': '0.5', 'Upper rhombic lip': '0.8', 'Upper-layer intratelencephalic': '0.6', 'Astrocyte': '4.4', 'Bergmann glia': '0.2', 'Central nervous system macrophage': '0.6', 'Choroid plexus epithelial cell': '52.1', 'Committed oligodendrocyte precursor': '41.5', 'Ependymal cell': '4.8', 'Oligodendrocyte': '53.1', 'Oligodendrocyte precursor cell': '2.4', 'Endothelial cell': '0.7', 'Pericyte': '0.3', 'Vascular associated smooth muscle cell': '0.0', 'Fibroblast': '17.4', 'Leukocyte': '1.1', 'Basophil': '0.0', 'Eosinophil': '0.0', 'Neutrophil': '0.0', 'Classical monocyte': '0.0', 'Non-classical monocyte': '0.0', 'Intermediate monocyte': '0.0', 'T-reg': '2.3', 'GdT-cell': '0.0', 'MAIT T-cell': '0.0', 'Memory CD4 T-cell': '0.0', 'Naive CD4 T-cell': '0.1', 'Memory CD8 T-cell': '0.2', 'Naive CD8 T-cell': '0.3', 'Memory B-cell': '0.0', 'Naive B-cell': '0.1', 'Plasmacytoid DC': '46.6', 'Myeloid DC': '8.5', 'NK-cell': '0.1', 'Total PBMC': '0.7', 'Vd2 gdTCR': '0.0', 'Memory CD4 T-cell Th1\\/Th17': '0.1', 'Memory CD4 T-cell Th17': '0.2', 'Memory CD4 T-cell Th2': '2.9', 'Non-Vd2 gdTCR': '0.1', 'Memory CD4 T-cell Th1': '0.3', 'Memory CD4 T-cell TFH': '0.5', 'Terminal effector memory CD4 T-cell': '0.0', 'Central memory CD8 T-cell': '4.8', 'Effector memory CD8 T-cell': '0.0', 'Terminal effector memory CD8 T-cell': '0.6', 'Non-switched memory B-cell': '0.0', 'Plasmablast': '3.3', 'Switched memory B-cell': '0.0', 'Exhausted memory B-cell': '0.7', 'Progenitor cell': '2.3', 'Memory T-reg': '1.3', 'Naive CD4 T-cell activated': '0.3', 'Naive CD8 T-cell activated': '0.6', 'Naive T-reg': '0.1'} | 1O6S, 2O72, 2OMT, 2OMU, 2OMV, 2OMX, 2OMY, 2OMZ, 3FF7, 3FF8, 3L6X, 3L6Y, 4ZT1, 4ZTE, 6CXY, 6OLE, 6OLF, 6OLG, 6VEL, 7STZ, 8H62 | {'Adipose Tissue': 1.2125261088039867, 'Adrenal Gland': 0.1914223992248062, 'Bladder': 39.2033519047619, 'Blood': 1.340954264800861, 'Blood Vessel': 0.3121561692883895, 'Brain': 0.8550442199091597, 'Breast': 38.54918344226579, 'Cervix Uteri': 23.539115789473684, 'Colon': 43.41292142490372, 'Esophagus': 53.97513367404844, 'Fallopian Tube': 14.900277777777776, 'Heart': 0.119140469221835, 'Kidney': 25.040449438202245, 'Liver': 26.60802654867257, 'Lung': 35.447986366782004, 'Muscle': 0.1378936151930261, 'Nerve': 17.518468982229404, 'Ovary': 3.6515122222222223, 'Pancreas': 56.89676829268293, 'Pituitary': 24.68741660777385, 'Prostate': 61.279967346938776, 'Salivary Gland': 92.01685185185184, 'Skin': 79.77571720232172, 'Small Intestine': 71.7519320855615, 'Spleen': 10.061029045643156, 'Stomach': 58.07813805013927, 'Testis': 0.8144204986149585, 'Thyroid': 135.176797856049, 'Uterus': 1.442593943661972, 'Vagina': 86.52345512820513} | KIF22 | MAAGGSTQQRRREMAAASAAAISGAGRCRLSKIGATRRPPPARVRVAVRLRPFVDGTAGASDPPCVRGMDSCSLEIANWRNHQETLKYQFDAFYGERSTQQDIYAGSVQPILRHLLEGQNASVLAYGPTGAGKTHTMLGSPEQPGVIPRALMDLLQLTREEGAEGRPWALSVTMSYLEIYQEKVLDLLDPASGDLVIREDCRGNILIPGLSQKPISSFADFERHFLPASRNRTVGATRLNQRSSRSHAVLLVKVDQRERLAPFRQREGKLYLIDLAGSEDNRRTGNKGLRLKESGAINTSLFVLGKVVDALNQGLPRVPYRDSKLTRLLQDSLGGSAHSILIANIAPERRFYLDTVSALNFAARSKEVINRPFTNESLQPHALGPVKLSQKELLGPPEAKRARGPEEEEIGSPEPMAAPASASQKLSPLQKLSSMDPAMLERLLSLDRLLASQGSQGAPLLSTPKRERMVLMKTVEEKDLEIERLKTKQKELEAKMLAQKAEEKENHCPTMLRPLSHRTVTGAKPLKKAVVMPLQLIQEQAASPNAEIHILKNKGRKRKLESLDALEPEEKAEDCWELQISPELLAHGRQKILDLLNEGSARDLRSLQRIGPKKAQLIVGWRELHGPFSQVEDLERVEGITGKQMESFLKANILGLAAGQRCGAS | Homo sapiens | Nucleus, Cytoplasm, cytoskeleton | Tissue enhanced (lymphoid) | {'Ciliated cells': '24.3', 'Basal respiratory cells': '52.8', 'Club cells': '30.3', 'Ionocytes': '32.0', 'Mucus glandular cells': '11.6', 'Serous glandular cells': '21.2', 'Gastric mucus-secreting cells': '24.8', 'Proximal enterocytes': '12.4', 'Paneth cells': '48.7', 'Distal enterocytes': '56.0', 'Intestinal goblet cells': '39.4', 'Exocrine glandular cells': '-0.590', 'Basal prostatic cells': '77.5', 'Prostatic glandular cells': '57.7', 'Breast glandular cells': '0.713', 'Breast myoepithelial cells': '0.686', 'Glandular and luminal cells': '33.1', 'Secretory cells': '32.7', 'Basal keratinocytes': '29.2', 'Suprabasal keratinocytes': '24.6', 'Basal squamous epithelial cells': '45.7', 'Squamous epithelial cells': '38.1', 'Alveolar cells type 1': '-0.018', 'Alveolar cells type 2': '0.018', 'Salivary duct cells': '13.7', 'Ductal cells': '0.422', 'Hepatocytes': '0.481', 'Cholangiocytes': '49.6', 'Proximal tubular cells': '0.134', 'Distal tubular cells': '64.5', 'Collecting duct cells': '62.2', 'Mesothelial cells': '0.413', 'Sertoli cells': '0.231', 'Granulosa cells': '22.9', 'Enteroendocrine cells': '40.4', 'Pancreatic endocrine cells': '27.2', 'Leydig cells': '0.092', 'Excitatory neurons': '4.6', 'Inhibitory neurons': '5.9', 'Cone photoreceptor cells': '20.4', 'Rod photoreceptor cells': '20.8', 'Bipolar cells': '24.2', 'Horizontal cells': '15.1', 'Astrocytes': '5.3', 'Oligodendrocyte precursor cells': '3.8', 'Oligodendrocytes': '4.9', 'Microglial cells': '4.5', 'Muller glia cells': '72.3', 'Schwann cells': '0.202', 'Spermatogonia': '0.462', 'Spermatocytes': '0.579', 'Early spermatids': '0.117', 'Late spermatids': '-0.158', 'Oocytes': '96.3', 'Cytotrophoblasts': '82.6', 'Syncytiotrophoblasts': '87.8', 'Extravillous trophoblasts': '88.9', 'Endothelial cells': '23.9', 'Lymphatic endothelial cells': '19.8', 'Cardiomyocytes': '0.597', 'Skeletal myocytes': '0.371', 'Smooth muscle cells': '30.7', 'Adipocytes': '16.5', 'Melanocytes': '0.432', 'Fibroblasts': '45.0', 'Peritubular cells': '0.044', 'Endometrial stromal cells': '18.7', 'Ovarian stromal cells': '50.5', 'Undifferentiated cells': '53.5', 'T-cells': '29.5', 'B-cells': '21.3', 'Plasma cells': '52.2', 'Nk-cells': '25.2', 'Granulocytes': '32.1', 'Monocytes': '25.6', 'Macrophages': '30.8', 'Hofbauer cells': '47.9', 'Kupffer cells': '44.6', 'Dendritic cells': '9.3', 'Langerhans cells': '0.373', 'Erythroid cells': '0.072', 'Adipocytes (Subcutaneous)': '-0.232', 'Adipocytes (Visceral)': '-0.219', 'Breast glandular cells (progenitors)': '0.569', 'Adipocytes (Breast)': '-0.652', 'Colon enterocytes': '0.268', 'Colon enteroendocrine cells': '0.049', 'Enteric glia cells': '-0.059', 'Mitotic cells (Colon)': '0.202', 'Mitotic cells (Heart)': '0.303', 'Podocytes': '-0.143', 'Ascending Loop of Henle cells': '0.543', 'Intercalated cells': '0.047', 'Cholangiocyte': '0.072', 'NK-cells (Liver)': '0.127', 'Respiratory ciliated cells': '0.188', 'Mitotic cells (Lung)': '0.450', 'NK-cells (Lung)': '0.101', 'B-cells (Lung)': '0.110', 'Alpha cells': '0.292', 'Beta cells': '0.217', 'Prostate glandular cells': '0.431', 'Prostate basal glandular cells': '0.423', 'Urothelial cells': '0.241', 'Keratinocyte (other)': '0.669', 'Keratinocyte (granular)': '-0.042', 'Hair cortex cells': '-0.171', 'Inner root sheath cells': '-0.065', 'Outer root sheath cells': '0.006', 'Sebaceous gland cells': '-0.091', 'Eccrine sweat gland cells': '-0.339', 'Adipocytes (Skin)': '-0.494', 'Mitotic cells (Skin)': '0.551', 'Parietal cells': '-0.109', 'Chief cells': '-0.055', 'Gastric mucous cells': '0.288', 'Gastric enteroendocrine cells': '0.067', 'Mitotic cells (Stomach)': '0.620', 'Parafollicular cells': '0.137', 'Thyroid glandular cells': '0.409', 'Mitotic cells (Thyroid)': '-0.016', 'Adrenal cortex cells': '0.294', 'Adrenal medulla cells': '0.086', 'Mitotic cells (Adrenal gland)': '0.396', 'Minor salivary glandular cells': '0.203', 'Minor salivary gland ductal cells': '-0.112', 'Minor salivary gland basal cells': '0.705', 'Mitotic cells (Minor salivary gland)': '0.724', 'Adipocytes (Minor salivary gland)': '0.299', 'Somatotropes': '-0.128', 'Lactotropes': '0.014', 'Gonadotropes': '0.140', 'Corticotropes': '0.088', 'Thyrotropes': '0.191', 'Undifferentiated cells (Pituitary gland)': '0.270', 'Mitotic cells (Spleen)': '0.585', 'Platelets': '-0.052', 'Erythrocytes': '0.215', 'Hematopoietic stem cells': '0.066', 'B-cells (Spleen)': '0.238', 'NK-cells (Spleen)': '0.094', 'Amygdala excitatory': '10.1', 'Cerebellar inhibitory': '11.5', 'Cge interneuron': '15.8', 'Deep-layer corticothalamic and 6b': '10.9', 'Deep-layer intratelencephalic': '10.0', 'Deep-layer near-projecting': '12.1', 'Eccentric medium spiny neuron': '13.1', 'Hippocampal ca1-3': '9.3', 'Hippocampal ca4': '12.2', 'Hippocampal dentate gyrus': '11.6', 'Lamp5-lhx6 and chandelier': '14.4', 'Lower rhombic lip': '16.5', 'Mammillary body': '18.6', 'Medium spiny neuron': '12.5', 'Mge interneuron': '13.9', 'Midbrain-derived inhibitory': '30.5', 'Miscellaneous': '9.7', 'Splatter': '15.9', 'Thalamic excitatory': '11.6', 'Upper rhombic lip': '19.6', 'Upper-layer intratelencephalic': '10.3', 'Astrocyte': '21.2', 'Bergmann glia': '18.4', 'Central nervous system macrophage': '11.3', 'Choroid plexus epithelial cell': '11.5', 'Committed oligodendrocyte precursor': '12.5', 'Ependymal cell': '17.5', 'Oligodendrocyte': '12.6', 'Oligodendrocyte precursor cell': '12.4', 'Endothelial cell': '9.6', 'Pericyte': '16.0', 'Vascular associated smooth muscle cell': '19.8', 'Fibroblast': '26.4', 'Leukocyte': '22.5', 'Basophil': '24.3', 'Eosinophil': '32.5', 'Neutrophil': '9.5', 'Classical monocyte': '10.1', 'Non-classical monocyte': '17.0', 'Intermediate monocyte': '29.7', 'T-reg': '49.2', 'GdT-cell': '39.9', 'MAIT T-cell': '39.7', 'Memory CD4 T-cell': '43.3', 'Naive CD4 T-cell': '50.4', 'Memory CD8 T-cell': '46.6', 'Naive CD8 T-cell': '51.5', 'Memory B-cell': '24.2', 'Naive B-cell': '21.5', 'Plasmacytoid DC': '16.4', 'Myeloid DC': '15.7', 'NK-cell': '53.8', 'Total PBMC': '27.4', 'Vd2 gdTCR': '36.6', 'Memory CD4 T-cell Th1\\/Th17': '54.3', 'Memory CD4 T-cell Th17': '70.4', 'Memory CD4 T-cell Th2': '73.9', 'Non-Vd2 gdTCR': '49.1', 'Memory CD4 T-cell Th1': '77.3', 'Memory CD4 T-cell TFH': '93.6', 'Terminal effector memory CD4 T-cell': '66.9', 'Central memory CD8 T-cell': '41.0', 'Effector memory CD8 T-cell': '55.9', 'Terminal effector memory CD8 T-cell': '46.1', 'Non-switched memory B-cell': '28.4', 'Plasmablast': '72.0', 'Switched memory B-cell': '35.5', 'Exhausted memory B-cell': '36.5', 'Progenitor cell': '25.7', 'Memory T-reg': '95.0', 'Naive CD4 T-cell activated': '18.2', 'Naive CD8 T-cell activated': '24.2', 'Naive T-reg': '54.0'} | 2EDU, 6NJE | {'Adipose Tissue': 11.376390365448504, 'Adrenal Gland': 8.589713178294573, 'Bladder': 15.476714285714287, 'Blood': 24.7057345532831, 'Blood Vessel': 14.226916104868916, 'Brain': 9.7878315669947, 'Breast': 17.74922440087146, 'Cervix Uteri': 15.907368421052633, 'Colon': 16.801667522464697, 'Esophagus': 15.742590311418686, 'Fallopian Tube': 15.530555555555557, 'Heart': 7.62959430894309, 'Kidney': 10.838808988764043, 'Liver': 6.996243805309735, 'Lung': 14.977318339100345, 'Muscle': 5.569960149439601, 'Nerve': 18.755242326332795, 'Ovary': 14.971027777777778, 'Pancreas': 4.727390243902439, 'Pituitary': 15.806335689045936, 'Prostate': 28.59808163265306, 'Salivary Gland': 13.21441975308642, 'Skin': 35.30904422332781, 'Small Intestine': 22.425716577540108, 'Spleen': 25.16746887966805, 'Stomach': 11.133189415041782, 'Testis': 51.964847645429366, 'Thyroid': 48.54188055130169, 'Uterus': 15.22199295774648, 'Vagina': 20.119153846153846} | [39.93, 46.46, 52.9, 44.21, 41.4, 39.93, 35.91, 38.61, 36.44, 36.25, 34.86, 32.82, 32.01, 32.75, 31.69, 35.64, 36.35, 34.66, 33.32, 32.71, 35.01, 30.17, 37.05, 36.53, 48.19, 58.22, 64.94, 73.22, 78.33, 82.63, 85.79, 89.39, 87.89, 85.58, 83.93, 89.1, 89.27, 90.66, 87.86, 86.2, 82.97, 72.75, 73.3, 76.44, 82.38, 82.41, 79.49, 86.6, 76.32, 85.48, 88.69, 84.35, 87.75, 90.57, 88.72, 89.46, 87.48, 85.3, 81.72, 79.46, 77.26, 69.01, 67.1, 62.83, 67.71, 74.96, 82.95, 86.74, 86.35, 86.49, 84.6, 85.99, 85.64, 87.19, 89.23, 89.3, 90.62, 84.21, 85.42, 83.34, 84.28, 89.8, 89.78, 87.53, 87.64, 85.98, 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0.82, 0.42, 0.02, 0.56, 0.25, 0.03, 0.1, 0.75, 0.25, 0.05, 0.14, 0.33, 0.26, 0.29, 0.14, 0.55, 0.66, 0.74, 0.79, 0.99, 0.99, 1.0, 1.0] | null | Component of an E-cadherin/ catenin adhesion complex composed of at least E-cadherin/CDH1, beta-catenin/CTNNB1 or gamma-catenin/JUP, and potentially alpha-catenin/CTNNA1. Forms a ternary complex composed of ADAM10, CADH1 and EPHA4, | null | null | KLRG1, SPEF1, DLGAP5, AJAP1, RAPGEF2, RAB8B, PIP5K1C, PKP2, TRPV4, CTNNB1, CAV1, DDR1, TBC1D2, CTNNA1, JUP, CTNND1, PSEN1, LIMA1, CDH1, JUP, ADAM10, CADH1 , EPHA4, | null | null | null | null | Homodimer | null | 79.91949 | 0.474025 | 73.433925 | 0.492977 | 1,093 |
P12830 | Q15004 | null | degron_data | CDH1 | MGPWSRSLSALLLLLQVSSWLCQEPEPCHPGFDAESYTFTVPRRHLERGRVLGRVNFEDCTGRQRTAYFSLDTRFKVGTDGVITVKRPLRFHNPQIHFLVYAWDSTYRKFSTKVTLNTVGHHHRPPPHQASVSGIQAELLTFPNSSPGLRRQKRDWVIPPISCPENEKGPFPKNLVQIKSNKDKEGKVFYSITGQGADTPPVGVFIIERETGWLKVTEPLDRERIATYTLFSHAVSSNGNAVEDPMEILITVTDQNDNKPEFTQEVFKGSVMEGALPGTSVMEVTATDADDDVNTYNAAIAYTILSQDPELPDKNMFTINRNTGVISVVTTGLDRESFPTYTLVVQAADLQGEGLSTTATAVITVTDTNDNPPIFNPTTYKGQVPENEANVVITTLKVTDADAPNTPAWEAVYTILNDDGGQFVVTTNPVNNDGILKTAKGLDFEAKQQYILHVAVTNVVPFEVSLTTSTATVTVDVLDVNEAPIFVPPEKRVEVSEDFGVGQEITSYTAQEPDTFMEQKITYRIWRDTANWLEINPDTGAISTRAELDREDFEHVKNSTYTALIIATDNGSPVATGTGTLLLILSDVNDNAPIPEPRTIFFCERNPKPQVINIIDADLPPNTSPFTAELTHGASANWTIQYNDPTQESIILKPKMALEVGDYKINLKLMDNQNKDQVTTLEVSVCDCEGAAGVCRKAQPVEAGLQIPAILGILGGILALLILILLLLLFLRRRAVVKEPLLPPEDDTRDNVYYYDEEGGGEEDQDFDLSQLHRGLDARPEVTRNDVAPTLMSVPRYLPRPANPDEIGNFIDENLKAADTDPTAPPYDSLLVFDYEGSGSEAASLSSLNSSESDKDQDYDYLNEWGNRFKKLADMYGGGEDD | Homo sapiens | Cell junction, adherens junction, Cell membrane, Endosome, Golgi apparatus, trans-Golgi network, Cytoplasm, Cell junction, desmosome | Tissue enhanced (parathyroid) | {'Ciliated cells': '119.1', 'Basal respiratory cells': '71.1', 'Club cells': '97.3', 'Ionocytes': '81.0', 'Mucus glandular cells': '155.0', 'Serous glandular cells': '67.8', 'Gastric mucus-secreting cells': '133.2', 'Proximal enterocytes': '140.9', 'Paneth cells': '125.1', 'Distal enterocytes': '307.5', 'Intestinal goblet cells': '173.5', 'Exocrine glandular cells': '-0.605', 'Basal prostatic cells': '68.3', 'Prostatic glandular cells': '186.7', 'Breast glandular cells': '0.773', 'Breast myoepithelial cells': '0.700', 'Glandular and luminal cells': '313.0', 'Secretory cells': '82.3', 'Basal keratinocytes': '102.5', 'Suprabasal keratinocytes': '162.6', 'Basal squamous epithelial cells': '51.0', 'Squamous epithelial cells': '106.9', 'Alveolar cells type 1': '0.437', 'Alveolar cells type 2': '0.706', 'Salivary duct cells': '95.9', 'Ductal cells': '0.541', 'Hepatocytes': '0.600', 'Cholangiocytes': '129.7', 'Proximal tubular cells': '0.042', 'Distal tubular cells': '0.0', 'Collecting duct cells': '143.9', 'Mesothelial cells': '0.799', 'Sertoli cells': '0.252', 'Granulosa cells': '12.9', 'Enteroendocrine cells': '92.4', 'Pancreatic endocrine cells': '78.1', 'Leydig cells': '0.264', 'Excitatory neurons': '0.7', 'Inhibitory neurons': '1.3', 'Cone photoreceptor cells': '0.0', 'Rod photoreceptor cells': '0.0', 'Bipolar cells': '0.2', 'Horizontal cells': '0.6', 'Astrocytes': '0.6', 'Oligodendrocyte precursor cells': '0.5', 'Oligodendrocytes': '29.9', 'Microglial cells': '0.9', 'Muller glia cells': '0.1', 'Schwann cells': '0.131', 'Spermatogonia': '0.392', 'Spermatocytes': '0.193', 'Early spermatids': '-0.217', 'Late spermatids': '-0.290', 'Oocytes': '16.9', 'Cytotrophoblasts': '119.2', 'Syncytiotrophoblasts': '45.0', 'Extravillous trophoblasts': '24.9', 'Endothelial cells': '6.1', 'Lymphatic endothelial cells': '0.4', 'Cardiomyocytes': '0.135', 'Skeletal myocytes': '0.107', 'Smooth muscle cells': '5.8', 'Adipocytes': '2.1', 'Melanocytes': '0.335', 'Fibroblasts': '6.5', 'Peritubular cells': '0.210', 'Endometrial stromal cells': '27.7', 'Ovarian stromal cells': '0.7', 'Undifferentiated cells': '101.6', 'T-cells': '2.9', 'B-cells': '4.4', 'Plasma cells': '6.1', 'Nk-cells': '0.0', 'Granulocytes': '8.4', 'Monocytes': '0.0', 'Macrophages': '6.0', 'Hofbauer cells': '4.3', 'Kupffer cells': '1.0', 'Dendritic cells': '5.9', 'Langerhans cells': '0.304', 'Erythroid cells': '0.036', 'Adipocytes (Subcutaneous)': '-0.081', 'Adipocytes (Visceral)': '-0.209', 'Breast glandular cells (progenitors)': '0.538', 'Adipocytes (Breast)': '-0.689', 'Colon enterocytes': '0.790', 'Colon enteroendocrine cells': '0.112', 'Enteric glia cells': '-0.048', 'Mitotic cells (Colon)': '0.299', 'Mitotic cells (Heart)': '0.120', 'Podocytes': '-0.118', 'Ascending Loop of Henle cells': '0.475', 'Intercalated cells': '0.212', 'Cholangiocyte': '0.090', 'NK-cells (Liver)': '-0.005', 'Respiratory ciliated cells': '-0.012', 'Mitotic cells (Lung)': '0.071', 'NK-cells (Lung)': '-0.266', 'B-cells (Lung)': '-0.296', 'Alpha cells': '0.270', 'Beta cells': '0.152', 'Prostate glandular cells': '0.764', 'Prostate basal glandular cells': '0.540', 'Urothelial cells': '0.205', 'Keratinocyte (other)': '0.510', 'Keratinocyte (granular)': '0.055', 'Hair cortex cells': '0.080', 'Inner root sheath cells': '0.131', 'Outer root sheath cells': '0.175', 'Sebaceous gland cells': '0.156', 'Eccrine sweat gland cells': '-0.207', 'Adipocytes (Skin)': '-0.244', 'Mitotic cells (Skin)': '0.442', 'Parietal cells': '0.654', 'Chief cells': '0.649', 'Gastric mucous cells': '0.781', 'Gastric enteroendocrine cells': '0.590', 'Mitotic cells (Stomach)': '0.445', 'Parafollicular cells': '0.173', 'Thyroid glandular cells': '0.865', 'Mitotic cells (Thyroid)': '-0.081', 'Adrenal cortex cells': '0.051', 'Adrenal medulla cells': '0.087', 'Mitotic cells (Adrenal gland)': '0.072', 'Minor salivary glandular cells': '0.371', 'Minor salivary gland ductal cells': '-0.142', 'Minor salivary gland basal cells': '0.582', 'Mitotic cells (Minor salivary gland)': '0.567', 'Adipocytes (Minor salivary gland)': '0.050', 'Somatotropes': '0.121', 'Lactotropes': '0.322', 'Gonadotropes': '0.330', 'Corticotropes': '0.180', 'Thyrotropes': '0.496', 'Undifferentiated cells (Pituitary gland)': '-0.108', 'Mitotic cells (Spleen)': '-0.228', 'Platelets': '-0.050', 'Erythrocytes': '-0.158', 'Hematopoietic stem cells': '-0.211', 'B-cells (Spleen)': '0.266', 'NK-cells (Spleen)': '0.309', 'Amygdala excitatory': '1.0', 'Cerebellar inhibitory': '0.9', 'Cge interneuron': '0.7', 'Deep-layer corticothalamic and 6b': '1.5', 'Deep-layer intratelencephalic': '0.7', 'Deep-layer near-projecting': '0.7', 'Eccentric medium spiny neuron': '0.6', 'Hippocampal ca1-3': '1.9', 'Hippocampal ca4': '1.2', 'Hippocampal dentate gyrus': '1.1', 'Lamp5-lhx6 and chandelier': '0.5', 'Lower rhombic lip': '0.8', 'Mammillary body': '0.6', 'Medium spiny neuron': '0.7', 'Mge interneuron': '1.7', 'Midbrain-derived inhibitory': '0.7', 'Miscellaneous': '0.9', 'Splatter': '3.8', 'Thalamic excitatory': '0.5', 'Upper rhombic lip': '0.8', 'Upper-layer intratelencephalic': '0.6', 'Astrocyte': '4.4', 'Bergmann glia': '0.2', 'Central nervous system macrophage': '0.6', 'Choroid plexus epithelial cell': '52.1', 'Committed oligodendrocyte precursor': '41.5', 'Ependymal cell': '4.8', 'Oligodendrocyte': '53.1', 'Oligodendrocyte precursor cell': '2.4', 'Endothelial cell': '0.7', 'Pericyte': '0.3', 'Vascular associated smooth muscle cell': '0.0', 'Fibroblast': '17.4', 'Leukocyte': '1.1', 'Basophil': '0.0', 'Eosinophil': '0.0', 'Neutrophil': '0.0', 'Classical monocyte': '0.0', 'Non-classical monocyte': '0.0', 'Intermediate monocyte': '0.0', 'T-reg': '2.3', 'GdT-cell': '0.0', 'MAIT T-cell': '0.0', 'Memory CD4 T-cell': '0.0', 'Naive CD4 T-cell': '0.1', 'Memory CD8 T-cell': '0.2', 'Naive CD8 T-cell': '0.3', 'Memory B-cell': '0.0', 'Naive B-cell': '0.1', 'Plasmacytoid DC': '46.6', 'Myeloid DC': '8.5', 'NK-cell': '0.1', 'Total PBMC': '0.7', 'Vd2 gdTCR': '0.0', 'Memory CD4 T-cell Th1\\/Th17': '0.1', 'Memory CD4 T-cell Th17': '0.2', 'Memory CD4 T-cell Th2': '2.9', 'Non-Vd2 gdTCR': '0.1', 'Memory CD4 T-cell Th1': '0.3', 'Memory CD4 T-cell TFH': '0.5', 'Terminal effector memory CD4 T-cell': '0.0', 'Central memory CD8 T-cell': '4.8', 'Effector memory CD8 T-cell': '0.0', 'Terminal effector memory CD8 T-cell': '0.6', 'Non-switched memory B-cell': '0.0', 'Plasmablast': '3.3', 'Switched memory B-cell': '0.0', 'Exhausted memory B-cell': '0.7', 'Progenitor cell': '2.3', 'Memory T-reg': '1.3', 'Naive CD4 T-cell activated': '0.3', 'Naive CD8 T-cell activated': '0.6', 'Naive T-reg': '0.1'} | 1O6S, 2O72, 2OMT, 2OMU, 2OMV, 2OMX, 2OMY, 2OMZ, 3FF7, 3FF8, 3L6X, 3L6Y, 4ZT1, 4ZTE, 6CXY, 6OLE, 6OLF, 6OLG, 6VEL, 7STZ, 8H62 | {'Adipose Tissue': 1.2125261088039867, 'Adrenal Gland': 0.1914223992248062, 'Bladder': 39.2033519047619, 'Blood': 1.340954264800861, 'Blood Vessel': 0.3121561692883895, 'Brain': 0.8550442199091597, 'Breast': 38.54918344226579, 'Cervix Uteri': 23.539115789473684, 'Colon': 43.41292142490372, 'Esophagus': 53.97513367404844, 'Fallopian Tube': 14.900277777777776, 'Heart': 0.119140469221835, 'Kidney': 25.040449438202245, 'Liver': 26.60802654867257, 'Lung': 35.447986366782004, 'Muscle': 0.1378936151930261, 'Nerve': 17.518468982229404, 'Ovary': 3.6515122222222223, 'Pancreas': 56.89676829268293, 'Pituitary': 24.68741660777385, 'Prostate': 61.279967346938776, 'Salivary Gland': 92.01685185185184, 'Skin': 79.77571720232172, 'Small Intestine': 71.7519320855615, 'Spleen': 10.061029045643156, 'Stomach': 58.07813805013927, 'Testis': 0.8144204986149585, 'Thyroid': 135.176797856049, 'Uterus': 1.442593943661972, 'Vagina': 86.52345512820513} | PCLAF | MVRTKADSVPGTYRKVVAARAPRKVLGSSTSATNSTSVSSRKAENKYAGGNPVCVRPTPKWQKGIGEFFRLSPKDSEKENQIPEEAGSSGLGKAKRKACPLQPDHTNDEKE | Homo sapiens | Nucleus, Cytoplasm, perinuclear region | Group enriched (bone marrow, lymphoid tissue) | {'Ciliated cells': '7.3', 'Basal respiratory cells': '39.7', 'Club cells': '10.3', 'Ionocytes': '7.0', 'Mucus glandular cells': '1.6', 'Serous glandular cells': '18.8', 'Gastric mucus-secreting cells': '15.3', 'Proximal enterocytes': '7.2', 'Paneth cells': '4.8', 'Distal enterocytes': '6.4', 'Intestinal goblet cells': '41.1', 'Exocrine glandular cells': '-0.242', 'Basal prostatic cells': '0.8', 'Prostatic glandular cells': '2.2', 'Breast glandular cells': '0.293', 'Breast myoepithelial cells': '0.274', 'Glandular and luminal cells': '14.7', 'Secretory cells': '2.4', 'Basal keratinocytes': '54.7', 'Suprabasal keratinocytes': '20.5', 'Basal squamous epithelial cells': '14.2', 'Squamous epithelial cells': '32.5', 'Alveolar cells type 1': '-0.207', 'Alveolar cells type 2': '0.224', 'Salivary duct cells': '5.5', 'Ductal cells': '0.405', 'Hepatocytes': '0.376', 'Cholangiocytes': '1.9', 'Proximal tubular cells': '-0.051', 'Distal tubular cells': '3.1', 'Collecting duct cells': '1.9', 'Mesothelial cells': '0.010', 'Sertoli cells': '-0.532', 'Granulosa cells': '8.1', 'Enteroendocrine cells': '27.6', 'Pancreatic endocrine cells': '40.8', 'Leydig cells': '-0.528', 'Excitatory neurons': '0.7', 'Inhibitory neurons': '0.5', 'Cone photoreceptor cells': '0.0', 'Rod photoreceptor cells': '2.5', 'Bipolar cells': '1.1', 'Horizontal cells': '2.5', 'Astrocytes': '0.0', 'Oligodendrocyte precursor cells': '0.0', 'Oligodendrocytes': '2.4', 'Microglial cells': '0.9', 'Muller glia cells': '0.6', 'Schwann cells': '0.130', 'Spermatogonia': '-0.246', 'Spermatocytes': '0.073', 'Early spermatids': '0.560', 'Late spermatids': '0.787', 'Oocytes': '16.9', 'Cytotrophoblasts': '93.6', 'Syncytiotrophoblasts': '44.7', 'Extravillous trophoblasts': '147.4', 'Endothelial cells': '7.7', 'Lymphatic endothelial cells': '0.5', 'Cardiomyocytes': '0.188', 'Skeletal myocytes': '-0.004', 'Smooth muscle cells': '8.8', 'Adipocytes': '1.3', 'Melanocytes': '0.350', 'Fibroblasts': '16.8', 'Peritubular cells': '-0.378', 'Endometrial stromal cells': '8.2', 'Ovarian stromal cells': '0.9', 'Undifferentiated cells': '185.2', 'T-cells': '15.4', 'B-cells': '16.5', 'Plasma cells': '86.5', 'Nk-cells': '12.6', 'Granulocytes': '6.9', 'Monocytes': '0.7', 'Macrophages': '16.7', 'Hofbauer cells': '92.9', 'Kupffer cells': '24.0', 'Dendritic cells': '2.4', 'Langerhans cells': '0.165', 'Erythroid cells': '0.106', 'Adipocytes (Subcutaneous)': '-0.137', 'Adipocytes (Visceral)': '-0.101', 'Breast glandular cells (progenitors)': '0.239', 'Adipocytes (Breast)': '-0.246', 'Colon enterocytes': '0.351', 'Colon enteroendocrine cells': '-0.085', 'Enteric glia cells': '-0.099', 'Mitotic cells (Colon)': '0.689', 'Mitotic cells (Heart)': '0.667', 'Podocytes': '-0.087', 'Ascending Loop of Henle cells': '0.534', 'Intercalated cells': '0.031', 'Cholangiocyte': '0.052', 'NK-cells (Liver)': '0.067', 'Respiratory ciliated cells': '-0.004', 'Mitotic cells (Lung)': '0.810', 'NK-cells (Lung)': '-0.168', 'B-cells (Lung)': '-0.052', 'Alpha cells': '0.213', 'Beta cells': '0.155', 'Prostate glandular cells': '0.218', 'Prostate basal glandular cells': '0.305', 'Urothelial cells': '0.366', 'Keratinocyte (other)': '0.084', 'Keratinocyte (granular)': '-0.413', 'Hair cortex cells': '0.264', 'Inner root sheath cells': '0.359', 'Outer root sheath cells': '0.486', 'Sebaceous gland cells': '0.247', 'Eccrine sweat gland cells': '0.159', 'Adipocytes (Skin)': '-0.057', 'Mitotic cells (Skin)': '0.695', 'Parietal cells': '0.353', 'Chief cells': '0.369', 'Gastric mucous cells': '0.679', 'Gastric enteroendocrine cells': '0.488', 'Mitotic cells (Stomach)': '0.821', 'Parafollicular cells': '-0.019', 'Thyroid glandular cells': '0.257', 'Mitotic cells (Thyroid)': '0.365', 'Adrenal cortex cells': '0.293', 'Adrenal medulla cells': '0.129', 'Mitotic cells (Adrenal gland)': '0.817', 'Minor salivary glandular cells': '0.102', 'Minor salivary gland ductal cells': '-0.273', 'Minor salivary gland basal cells': '0.666', 'Mitotic cells (Minor salivary gland)': '0.895', 'Adipocytes (Minor salivary gland)': '0.117', 'Somatotropes': '0.082', 'Lactotropes': '0.067', 'Gonadotropes': '-0.052', 'Corticotropes': '0.076', 'Thyrotropes': '0.044', 'Undifferentiated cells (Pituitary gland)': '0.059', 'Mitotic cells (Spleen)': '0.885', 'Platelets': '0.159', 'Erythrocytes': '0.310', 'Hematopoietic stem cells': '0.358', 'B-cells (Spleen)': '-0.092', 'NK-cells (Spleen)': '-0.198', 'Amygdala excitatory': '0.3', 'Cerebellar inhibitory': '0.2', 'Cge interneuron': '0.2', 'Deep-layer corticothalamic and 6b': '0.3', 'Deep-layer intratelencephalic': '0.3', 'Deep-layer near-projecting': '0.8', 'Eccentric medium spiny neuron': '0.4', 'Hippocampal ca1-3': '0.4', 'Hippocampal ca4': '0.9', 'Hippocampal dentate gyrus': '0.2', 'Lamp5-lhx6 and chandelier': '0.1', 'Lower rhombic lip': '0.7', 'Mammillary body': '0.5', 'Medium spiny neuron': '0.3', 'Mge interneuron': '0.2', 'Midbrain-derived inhibitory': '0.3', 'Miscellaneous': '0.3', 'Splatter': '0.4', 'Thalamic excitatory': '0.5', 'Upper rhombic lip': '0.0', 'Upper-layer intratelencephalic': '0.5', 'Astrocyte': '0.5', 'Bergmann glia': '0.2', 'Central nervous system macrophage': '0.4', 'Choroid plexus epithelial cell': '0.2', 'Committed oligodendrocyte precursor': '0.4', 'Ependymal cell': '1.1', 'Oligodendrocyte': '1.6', 'Oligodendrocyte precursor cell': '0.2', 'Endothelial cell': '0.1', 'Pericyte': '0.3', 'Vascular associated smooth muscle cell': '0.0', 'Fibroblast': '0.3', 'Leukocyte': '0.3', 'Basophil': '4.7', 'Eosinophil': '0.9', 'Neutrophil': '13.5', 'Classical monocyte': '0.4', 'Non-classical monocyte': '0.6', 'Intermediate monocyte': '2.5', 'T-reg': '13.2', 'GdT-cell': '1.4', 'MAIT T-cell': '2.3', 'Memory CD4 T-cell': '4.4', 'Naive CD4 T-cell': '0.4', 'Memory CD8 T-cell': '4.2', 'Naive CD8 T-cell': '0.4', 'Memory B-cell': '2.0', 'Naive B-cell': '0.6', 'Plasmacytoid DC': '2.7', 'Myeloid DC': '2.5', 'NK-cell': '0.9', 'Total PBMC': '6.3', 'Vd2 gdTCR': '3.0', 'Memory CD4 T-cell Th1\\/Th17': '0.5', 'Memory CD4 T-cell Th17': '0.5', 'Memory CD4 T-cell Th2': '0.7', 'Non-Vd2 gdTCR': '2.8', 'Memory CD4 T-cell Th1': '0.9', 'Memory CD4 T-cell TFH': '0.6', 'Terminal effector memory CD4 T-cell': '3.0', 'Central memory CD8 T-cell': '6.6', 'Effector memory CD8 T-cell': '16.5', 'Terminal effector memory CD8 T-cell': '2.7', 'Non-switched memory B-cell': '4.3', 'Plasmablast': '58.9', 'Switched memory B-cell': '5.0', 'Exhausted memory B-cell': '11.5', 'Progenitor cell': '11.9', 'Memory T-reg': '1.7', 'Naive CD4 T-cell activated': '0.4', 'Naive CD8 T-cell activated': '0.3', 'Naive T-reg': '0.9'} | 4D2G, 6EHT, 6GWS, 6IIW | {'Adipose Tissue': 0.3581098546511628, 'Adrenal Gland': 0.4683213333333333, 'Bladder': 0.5697461904761905, 'Blood': 6.4377733713670615, 'Blood Vessel': 0.2171170262172284, 'Brain': 0.2037596642694928, 'Breast': 0.4111872156862745, 'Cervix Uteri': 0.5264963157894736, 'Colon': 1.10737951732991, 'Esophagus': 1.9398750304498271, 'Fallopian Tube': 0.3396, 'Heart': 0.0971625342624854, 'Kidney': 0.4090478651685393, 'Liver': 0.6143054424778761, 'Lung': 1.2743496678200692, 'Muscle': 0.0406215168119551, 'Nerve': 0.1882828481421647, 'Ovary': 0.2730282777777778, 'Pancreas': 0.3273265548780488, 'Pituitary': 0.4056313780918728, 'Prostate': 0.6551157551020408, 'Salivary Gland': 0.926897098765432, 'Skin': 4.78119631840796, 'Small Intestine': 2.485380481283422, 'Spleen': 2.635192531120332, 'Stomach': 1.3098355710306406, 'Testis': 6.981042659279778, 'Thyroid': 0.8270521898928024, 'Uterus': 0.2222339436619718, 'Vagina': 2.0549375} | [39.93, 46.46, 52.9, 44.21, 41.4, 39.93, 35.91, 38.61, 36.44, 36.25, 34.86, 32.82, 32.01, 32.75, 31.69, 35.64, 36.35, 34.66, 33.32, 32.71, 35.01, 30.17, 37.05, 36.53, 48.19, 58.22, 64.94, 73.22, 78.33, 82.63, 85.79, 89.39, 87.89, 85.58, 83.93, 89.1, 89.27, 90.66, 87.86, 86.2, 82.97, 72.75, 73.3, 76.44, 82.38, 82.41, 79.49, 86.6, 76.32, 85.48, 88.69, 84.35, 87.75, 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0.78, 0.42, 0.97, 0.83, 0.66, 0.85, 0.58, 0.73, 0.37, 0.5, 0.73, 0.81, 0.69, 0.59, 0.48, 0.82, 0.9, 0.7, 0.77, 0.91, 0.76, 0.95, 0.94, 0.72, 0.88, 0.8, 0.82, 0.89, 0.64, 0.91, 0.92, 0.77, 0.89, 0.89, 0.78, 0.95, 0.74, 0.93, 0.93, 0.88, 0.85, 0.82, 0.86, 0.91, 0.88, 0.89, 0.85, 0.89, 0.88, 0.82, 1.0, 0.93, 1.0, 0.99] | null | Component of an E-cadherin/ catenin adhesion complex composed of at least E-cadherin/CDH1, beta-catenin/CTNNB1 or gamma-catenin/JUP, and potentially alpha-catenin/CTNNA1. Forms a ternary complex composed of ADAM10, CADH1 and EPHA4, | null | null | KLRG1, SPEF1, DLGAP5, AJAP1, RAPGEF2, RAB8B, PIP5K1C, PKP2, TRPV4, CTNNB1, CAV1, DDR1, TBC1D2, CTNNA1, JUP, CTNND1, PSEN1, LIMA1, CDH1, JUP, ADAM10, CADH1 , EPHA4, | null | null | null | null | Homodimer | null | 79.91949 | 0.474025 | 65.387297 | 0.814324 | 2,970 |
P12830 | Q15303 | null | degron_data | CDH1 | MGPWSRSLSALLLLLQVSSWLCQEPEPCHPGFDAESYTFTVPRRHLERGRVLGRVNFEDCTGRQRTAYFSLDTRFKVGTDGVITVKRPLRFHNPQIHFLVYAWDSTYRKFSTKVTLNTVGHHHRPPPHQASVSGIQAELLTFPNSSPGLRRQKRDWVIPPISCPENEKGPFPKNLVQIKSNKDKEGKVFYSITGQGADTPPVGVFIIERETGWLKVTEPLDRERIATYTLFSHAVSSNGNAVEDPMEILITVTDQNDNKPEFTQEVFKGSVMEGALPGTSVMEVTATDADDDVNTYNAAIAYTILSQDPELPDKNMFTINRNTGVISVVTTGLDRESFPTYTLVVQAADLQGEGLSTTATAVITVTDTNDNPPIFNPTTYKGQVPENEANVVITTLKVTDADAPNTPAWEAVYTILNDDGGQFVVTTNPVNNDGILKTAKGLDFEAKQQYILHVAVTNVVPFEVSLTTSTATVTVDVLDVNEAPIFVPPEKRVEVSEDFGVGQEITSYTAQEPDTFMEQKITYRIWRDTANWLEINPDTGAISTRAELDREDFEHVKNSTYTALIIATDNGSPVATGTGTLLLILSDVNDNAPIPEPRTIFFCERNPKPQVINIIDADLPPNTSPFTAELTHGASANWTIQYNDPTQESIILKPKMALEVGDYKINLKLMDNQNKDQVTTLEVSVCDCEGAAGVCRKAQPVEAGLQIPAILGILGGILALLILILLLLLFLRRRAVVKEPLLPPEDDTRDNVYYYDEEGGGEEDQDFDLSQLHRGLDARPEVTRNDVAPTLMSVPRYLPRPANPDEIGNFIDENLKAADTDPTAPPYDSLLVFDYEGSGSEAASLSSLNSSESDKDQDYDYLNEWGNRFKKLADMYGGGEDD | Homo sapiens | Cell junction, adherens junction, Cell membrane, Endosome, Golgi apparatus, trans-Golgi network, Cytoplasm, Cell junction, desmosome | Tissue enhanced (parathyroid) | {'Ciliated cells': '119.1', 'Basal respiratory cells': '71.1', 'Club cells': '97.3', 'Ionocytes': '81.0', 'Mucus glandular cells': '155.0', 'Serous glandular cells': '67.8', 'Gastric mucus-secreting cells': '133.2', 'Proximal enterocytes': '140.9', 'Paneth cells': '125.1', 'Distal enterocytes': '307.5', 'Intestinal goblet cells': '173.5', 'Exocrine glandular cells': '-0.605', 'Basal prostatic cells': '68.3', 'Prostatic glandular cells': '186.7', 'Breast glandular cells': '0.773', 'Breast myoepithelial cells': '0.700', 'Glandular and luminal cells': '313.0', 'Secretory cells': '82.3', 'Basal keratinocytes': '102.5', 'Suprabasal keratinocytes': '162.6', 'Basal squamous epithelial cells': '51.0', 'Squamous epithelial cells': '106.9', 'Alveolar cells type 1': '0.437', 'Alveolar cells type 2': '0.706', 'Salivary duct cells': '95.9', 'Ductal cells': '0.541', 'Hepatocytes': '0.600', 'Cholangiocytes': '129.7', 'Proximal tubular cells': '0.042', 'Distal tubular cells': '0.0', 'Collecting duct cells': '143.9', 'Mesothelial cells': '0.799', 'Sertoli cells': '0.252', 'Granulosa cells': '12.9', 'Enteroendocrine cells': '92.4', 'Pancreatic endocrine cells': '78.1', 'Leydig cells': '0.264', 'Excitatory neurons': '0.7', 'Inhibitory neurons': '1.3', 'Cone photoreceptor cells': '0.0', 'Rod photoreceptor cells': '0.0', 'Bipolar cells': '0.2', 'Horizontal cells': '0.6', 'Astrocytes': '0.6', 'Oligodendrocyte precursor cells': '0.5', 'Oligodendrocytes': '29.9', 'Microglial cells': '0.9', 'Muller glia cells': '0.1', 'Schwann cells': '0.131', 'Spermatogonia': '0.392', 'Spermatocytes': '0.193', 'Early spermatids': '-0.217', 'Late spermatids': '-0.290', 'Oocytes': '16.9', 'Cytotrophoblasts': '119.2', 'Syncytiotrophoblasts': '45.0', 'Extravillous trophoblasts': '24.9', 'Endothelial cells': '6.1', 'Lymphatic endothelial cells': '0.4', 'Cardiomyocytes': '0.135', 'Skeletal myocytes': '0.107', 'Smooth muscle cells': '5.8', 'Adipocytes': '2.1', 'Melanocytes': '0.335', 'Fibroblasts': '6.5', 'Peritubular cells': '0.210', 'Endometrial stromal cells': '27.7', 'Ovarian stromal cells': '0.7', 'Undifferentiated cells': '101.6', 'T-cells': '2.9', 'B-cells': '4.4', 'Plasma cells': '6.1', 'Nk-cells': '0.0', 'Granulocytes': '8.4', 'Monocytes': '0.0', 'Macrophages': '6.0', 'Hofbauer cells': '4.3', 'Kupffer cells': '1.0', 'Dendritic cells': '5.9', 'Langerhans cells': '0.304', 'Erythroid cells': '0.036', 'Adipocytes (Subcutaneous)': '-0.081', 'Adipocytes (Visceral)': '-0.209', 'Breast glandular cells (progenitors)': '0.538', 'Adipocytes (Breast)': '-0.689', 'Colon enterocytes': '0.790', 'Colon enteroendocrine cells': '0.112', 'Enteric glia cells': '-0.048', 'Mitotic cells (Colon)': '0.299', 'Mitotic cells (Heart)': '0.120', 'Podocytes': '-0.118', 'Ascending Loop of Henle cells': '0.475', 'Intercalated cells': '0.212', 'Cholangiocyte': '0.090', 'NK-cells (Liver)': '-0.005', 'Respiratory ciliated cells': '-0.012', 'Mitotic cells (Lung)': '0.071', 'NK-cells (Lung)': '-0.266', 'B-cells (Lung)': '-0.296', 'Alpha cells': '0.270', 'Beta cells': '0.152', 'Prostate glandular cells': '0.764', 'Prostate basal glandular cells': '0.540', 'Urothelial cells': '0.205', 'Keratinocyte (other)': '0.510', 'Keratinocyte (granular)': '0.055', 'Hair cortex cells': '0.080', 'Inner root sheath cells': '0.131', 'Outer root sheath cells': '0.175', 'Sebaceous gland cells': '0.156', 'Eccrine sweat gland cells': '-0.207', 'Adipocytes (Skin)': '-0.244', 'Mitotic cells (Skin)': '0.442', 'Parietal cells': '0.654', 'Chief cells': '0.649', 'Gastric mucous cells': '0.781', 'Gastric enteroendocrine cells': '0.590', 'Mitotic cells (Stomach)': '0.445', 'Parafollicular cells': '0.173', 'Thyroid glandular cells': '0.865', 'Mitotic cells (Thyroid)': '-0.081', 'Adrenal cortex cells': '0.051', 'Adrenal medulla cells': '0.087', 'Mitotic cells (Adrenal gland)': '0.072', 'Minor salivary glandular cells': '0.371', 'Minor salivary gland ductal cells': '-0.142', 'Minor salivary gland basal cells': '0.582', 'Mitotic cells (Minor salivary gland)': '0.567', 'Adipocytes (Minor salivary gland)': '0.050', 'Somatotropes': '0.121', 'Lactotropes': '0.322', 'Gonadotropes': '0.330', 'Corticotropes': '0.180', 'Thyrotropes': '0.496', 'Undifferentiated cells (Pituitary gland)': '-0.108', 'Mitotic cells (Spleen)': '-0.228', 'Platelets': '-0.050', 'Erythrocytes': '-0.158', 'Hematopoietic stem cells': '-0.211', 'B-cells (Spleen)': '0.266', 'NK-cells (Spleen)': '0.309', 'Amygdala excitatory': '1.0', 'Cerebellar inhibitory': '0.9', 'Cge interneuron': '0.7', 'Deep-layer corticothalamic and 6b': '1.5', 'Deep-layer intratelencephalic': '0.7', 'Deep-layer near-projecting': '0.7', 'Eccentric medium spiny neuron': '0.6', 'Hippocampal ca1-3': '1.9', 'Hippocampal ca4': '1.2', 'Hippocampal dentate gyrus': '1.1', 'Lamp5-lhx6 and chandelier': '0.5', 'Lower rhombic lip': '0.8', 'Mammillary body': '0.6', 'Medium spiny neuron': '0.7', 'Mge interneuron': '1.7', 'Midbrain-derived inhibitory': '0.7', 'Miscellaneous': '0.9', 'Splatter': '3.8', 'Thalamic excitatory': '0.5', 'Upper rhombic lip': '0.8', 'Upper-layer intratelencephalic': '0.6', 'Astrocyte': '4.4', 'Bergmann glia': '0.2', 'Central nervous system macrophage': '0.6', 'Choroid plexus epithelial cell': '52.1', 'Committed oligodendrocyte precursor': '41.5', 'Ependymal cell': '4.8', 'Oligodendrocyte': '53.1', 'Oligodendrocyte precursor cell': '2.4', 'Endothelial cell': '0.7', 'Pericyte': '0.3', 'Vascular associated smooth muscle cell': '0.0', 'Fibroblast': '17.4', 'Leukocyte': '1.1', 'Basophil': '0.0', 'Eosinophil': '0.0', 'Neutrophil': '0.0', 'Classical monocyte': '0.0', 'Non-classical monocyte': '0.0', 'Intermediate monocyte': '0.0', 'T-reg': '2.3', 'GdT-cell': '0.0', 'MAIT T-cell': '0.0', 'Memory CD4 T-cell': '0.0', 'Naive CD4 T-cell': '0.1', 'Memory CD8 T-cell': '0.2', 'Naive CD8 T-cell': '0.3', 'Memory B-cell': '0.0', 'Naive B-cell': '0.1', 'Plasmacytoid DC': '46.6', 'Myeloid DC': '8.5', 'NK-cell': '0.1', 'Total PBMC': '0.7', 'Vd2 gdTCR': '0.0', 'Memory CD4 T-cell Th1\\/Th17': '0.1', 'Memory CD4 T-cell Th17': '0.2', 'Memory CD4 T-cell Th2': '2.9', 'Non-Vd2 gdTCR': '0.1', 'Memory CD4 T-cell Th1': '0.3', 'Memory CD4 T-cell TFH': '0.5', 'Terminal effector memory CD4 T-cell': '0.0', 'Central memory CD8 T-cell': '4.8', 'Effector memory CD8 T-cell': '0.0', 'Terminal effector memory CD8 T-cell': '0.6', 'Non-switched memory B-cell': '0.0', 'Plasmablast': '3.3', 'Switched memory B-cell': '0.0', 'Exhausted memory B-cell': '0.7', 'Progenitor cell': '2.3', 'Memory T-reg': '1.3', 'Naive CD4 T-cell activated': '0.3', 'Naive CD8 T-cell activated': '0.6', 'Naive T-reg': '0.1'} | 1O6S, 2O72, 2OMT, 2OMU, 2OMV, 2OMX, 2OMY, 2OMZ, 3FF7, 3FF8, 3L6X, 3L6Y, 4ZT1, 4ZTE, 6CXY, 6OLE, 6OLF, 6OLG, 6VEL, 7STZ, 8H62 | {'Adipose Tissue': 1.2125261088039867, 'Adrenal Gland': 0.1914223992248062, 'Bladder': 39.2033519047619, 'Blood': 1.340954264800861, 'Blood Vessel': 0.3121561692883895, 'Brain': 0.8550442199091597, 'Breast': 38.54918344226579, 'Cervix Uteri': 23.539115789473684, 'Colon': 43.41292142490372, 'Esophagus': 53.97513367404844, 'Fallopian Tube': 14.900277777777776, 'Heart': 0.119140469221835, 'Kidney': 25.040449438202245, 'Liver': 26.60802654867257, 'Lung': 35.447986366782004, 'Muscle': 0.1378936151930261, 'Nerve': 17.518468982229404, 'Ovary': 3.6515122222222223, 'Pancreas': 56.89676829268293, 'Pituitary': 24.68741660777385, 'Prostate': 61.279967346938776, 'Salivary Gland': 92.01685185185184, 'Skin': 79.77571720232172, 'Small Intestine': 71.7519320855615, 'Spleen': 10.061029045643156, 'Stomach': 58.07813805013927, 'Testis': 0.8144204986149585, 'Thyroid': 135.176797856049, 'Uterus': 1.442593943661972, 'Vagina': 86.52345512820513} | ERBB4 | MKPATGLWVWVSLLVAAGTVQPSDSQSVCAGTENKLSSLSDLEQQYRALRKYYENCEVVMGNLEITSIEHNRDLSFLRSVREVTGYVLVALNQFRYLPLENLRIIRGTKLYEDRYALAIFLNYRKDGNFGLQELGLKNLTEILNGGVYVDQNKFLCYADTIHWQDIVRNPWPSNLTLVSTNGSSGCGRCHKSCTGRCWGPTENHCQTLTRTVCAEQCDGRCYGPYVSDCCHRECAGGCSGPKDTDCFACMNFNDSGACVTQCPQTFVYNPTTFQLEHNFNAKYTYGAFCVKKCPHNFVVDSSSCVRACPSSKMEVEENGIKMCKPCTDICPKACDGIGTGSLMSAQTVDSSNIDKFINCTKINGNLIFLVTGIHGDPYNAIEAIDPEKLNVFRTVREITGFLNIQSWPPNMTDFSVFSNLVTIGGRVLYSGLSLLILKQQGITSLQFQSLKEISAGNIYITDNSNLCYYHTINWTTLFSTINQRIVIRDNRKAENCTAEGMVCNHLCSSDGCWGPGPDQCLSCRRFSRGRICIESCNLYDGEFREFENGSICVECDPQCEKMEDGLLTCHGPGPDNCTKCSHFKDGPNCVEKCPDGLQGANSFIFKYADPDRECHPCHPNCTQGCNGPTSHDCIYYPWTGHSTLPQHARTPLIAAGVIGGLFILVIVGLTFAVYVRRKSIKKKRALRRFLETELVEPLTPSGTAPNQAQLRILKETELKRVKVLGSGAFGTVYKGIWVPEGETVKIPVAIKILNETTGPKANVEFMDEALIMASMDHPHLVRLLGVCLSPTIQLVTQLMPHGCLLEYVHEHKDNIGSQLLLNWCVQIAKGMMYLEERRLVHRDLAARNVLVKSPNHVKITDFGLARLLEGDEKEYNADGGKMPIKWMALECIHYRKFTHQSDVWSYGVTIWELMTFGGKPYDGIPTREIPDLLEKGERLPQPPICTIDVYMVMVKCWMIDADSRPKFKELAAEFSRMARDPQRYLVIQGDDRMKLPSPNDSKFFQNLLDEEDLEDMMDAEEYLVPQAFNIPPPIYTSRARIDSNRSEIGHSPPPAYTPMSGNQFVYRDGGFAAEQGVSVPYRAPTSTIPEAPVAQGATAEIFDDSCCNGTLRKPVAPHVQEDSSTQRYSADPTVFAPERSPRGELDEEGYMTPMRDKPKQEYLNPVEENPFVSRRKNGDLQALDNPEYHNASNGPPKAEDEYVNEPLYLNTFANTLGKAEYLKNNILSMPEKAKKAFDNPDYWNHSLPPRSTLQHPDYLQEYSTKYFYKQNGRIRPIVAENPEYLSEFSLKPGTVLPPPPYRHRNTVV | Homo sapiens | Cell membrane, Nucleus, Mitochondrion | Tissue enhanced (brain, fallopian tube) | {'Ciliated cells': '43.3', 'Basal respiratory cells': '1.0', 'Club cells': '5.5', 'Ionocytes': '2.2', 'Mucus glandular cells': '19.8', 'Serous glandular cells': '18.7', 'Gastric mucus-secreting cells': '0.0', 'Proximal enterocytes': '0.0', 'Paneth cells': '0.0', 'Distal enterocytes': '0.2', 'Intestinal goblet cells': '0.0', 'Exocrine glandular cells': '-0.196', 'Basal prostatic cells': '14.0', 'Prostatic glandular cells': '3.0', 'Breast glandular cells': '0.805', 'Breast myoepithelial cells': '0.591', 'Glandular and luminal cells': '20.8', 'Secretory cells': '35.1', 'Basal keratinocytes': '0.5', 'Suprabasal keratinocytes': '0.5', 'Basal squamous epithelial cells': '0.9', 'Squamous epithelial cells': '0.2', 'Alveolar cells type 1': '0.095', 'Alveolar cells type 2': '0.569', 'Salivary duct cells': '5.7', 'Ductal cells': '0.455', 'Hepatocytes': '0.138', 'Cholangiocytes': '1.9', 'Proximal tubular cells': '0.143', 'Distal tubular cells': '3.1', 'Collecting duct cells': '11.7', 'Mesothelial cells': '0.728', 'Sertoli cells': '0.810', 'Granulosa cells': '2.9', 'Enteroendocrine cells': '0.0', 'Pancreatic endocrine cells': '0.0', 'Leydig cells': '0.501', 'Excitatory neurons': '59.8', 'Inhibitory neurons': '5860.5', 'Cone photoreceptor cells': '0.0', 'Rod photoreceptor cells': '1.5', 'Bipolar cells': '11.3', 'Horizontal cells': '13.2', 'Astrocytes': '1916.0', 'Oligodendrocyte precursor cells': '2222.9', 'Oligodendrocytes': '977.4', 'Microglial cells': '92.1', 'Muller glia cells': '8.6', 'Schwann cells': '0.538', 'Spermatogonia': '0.401', 'Spermatocytes': '0.134', 'Early spermatids': '-0.387', 'Late spermatids': '-0.613', 'Oocytes': '10.3', 'Cytotrophoblasts': '0.1', 'Syncytiotrophoblasts': '0.0', 'Extravillous trophoblasts': '0.2', 'Endothelial cells': '0.8', 'Lymphatic endothelial cells': '0.5', 'Cardiomyocytes': '0.701', 'Skeletal myocytes': '0.401', 'Smooth muscle cells': '4.2', 'Adipocytes': '0.7', 'Melanocytes': '-0.054', 'Fibroblasts': '1.4', 'Peritubular cells': '0.433', 'Endometrial stromal cells': '0.8', 'Ovarian stromal cells': '0.1', 'Undifferentiated cells': '0.1', 'T-cells': '0.3', 'B-cells': '0.1', 'Plasma cells': '0.5', 'Nk-cells': '0.0', 'Granulocytes': '0.4', 'Monocytes': '0.0', 'Macrophages': '0.4', 'Hofbauer cells': '0.1', 'Kupffer cells': '0.0', 'Dendritic cells': '0.0', 'Langerhans cells': '-0.049', 'Erythroid cells': '0.066', 'Adipocytes (Subcutaneous)': '0.043', 'Adipocytes (Visceral)': '-0.064', 'Breast glandular cells (progenitors)': '0.433', 'Adipocytes (Breast)': '-0.572', 'Colon enterocytes': '-0.126', 'Colon enteroendocrine cells': '0.417', 'Enteric glia cells': '0.335', 'Mitotic cells (Colon)': '-0.206', 'Mitotic cells (Heart)': '0.323', 'Podocytes': '0.138', 'Ascending Loop of Henle cells': '0.522', 'Intercalated cells': '0.235', 'Cholangiocyte': '0.258', 'NK-cells (Liver)': '0.137', 'Respiratory ciliated cells': '0.426', 'Mitotic cells (Lung)': '0.031', 'NK-cells (Lung)': '-0.288', 'B-cells (Lung)': '-0.160', 'Alpha cells': '0.211', 'Beta cells': '0.161', 'Prostate glandular cells': '0.210', 'Prostate basal glandular cells': '0.403', 'Urothelial cells': '0.338', 'Keratinocyte (other)': '-0.128', 'Keratinocyte (granular)': '-0.176', 'Hair cortex cells': '0.170', 'Inner root sheath cells': '0.177', 'Outer root sheath cells': '0.254', 'Sebaceous gland cells': '0.064', 'Eccrine sweat gland cells': '0.666', 'Adipocytes (Skin)': '0.238', 'Mitotic cells (Skin)': '0.108', 'Parietal cells': '0.689', 'Chief cells': '0.690', 'Gastric mucous cells': '0.500', 'Gastric enteroendocrine cells': '0.535', 'Mitotic cells (Stomach)': '0.140', 'Parafollicular cells': '0.142', 'Thyroid glandular cells': '0.490', 'Mitotic cells (Thyroid)': '-0.079', 'Adrenal cortex cells': '0.122', 'Adrenal medulla cells': '0.572', 'Mitotic cells (Adrenal gland)': '0.087', 'Minor salivary glandular cells': '0.671', 'Minor salivary gland ductal cells': '0.386', 'Minor salivary gland basal cells': '-0.507', 'Mitotic cells (Minor salivary gland)': '-0.555', 'Adipocytes (Minor salivary gland)': '-0.338', 'Somatotropes': '-0.436', 'Lactotropes': '-0.411', 'Gonadotropes': '-0.077', 'Corticotropes': '0.121', 'Thyrotropes': '0.067', 'Undifferentiated cells (Pituitary gland)': '0.607', 'Mitotic cells (Spleen)': '-0.207', 'Platelets': '-0.165', 'Erythrocytes': '-0.071', 'Hematopoietic stem cells': '-0.203', 'B-cells (Spleen)': '0.117', 'NK-cells (Spleen)': '0.233', 'Amygdala excitatory': '147.9', 'Cerebellar inhibitory': '19.4', 'Cge interneuron': '8806.8', 'Deep-layer corticothalamic and 6b': '161.1', 'Deep-layer intratelencephalic': '44.3', 'Deep-layer near-projecting': '39.7', 'Eccentric medium spiny neuron': '8570.1', 'Hippocampal ca1-3': '32.7', 'Hippocampal ca4': '9.7', 'Hippocampal dentate gyrus': '25.1', 'Lamp5-lhx6 and chandelier': '11575.6', 'Lower rhombic lip': '1192.2', 'Mammillary body': '32.7', 'Medium spiny neuron': '1394.4', 'Mge interneuron': '8483.6', 'Midbrain-derived inhibitory': '120.7', 'Miscellaneous': '330.7', 'Splatter': '2055.3', 'Thalamic excitatory': '115.4', 'Upper rhombic lip': '1183.4', 'Upper-layer intratelencephalic': '37.6', 'Astrocyte': '3770.2', 'Bergmann glia': '1997.7', 'Central nervous system macrophage': '41.4', 'Choroid plexus epithelial cell': '408.5', 'Committed oligodendrocyte precursor': '3149.7', 'Ependymal cell': '2292.5', 'Oligodendrocyte': '1798.7', 'Oligodendrocyte precursor cell': '3808.6', 'Endothelial cell': '46.0', 'Pericyte': '69.0', 'Vascular associated smooth muscle cell': '562.4', 'Fibroblast': '63.5', 'Leukocyte': '46.1', 'Basophil': '0.0', 'Eosinophil': '0.0', 'Neutrophil': '0.0', 'Classical monocyte': '0.0', 'Non-classical monocyte': '0.0', 'Intermediate monocyte': '0.0', 'T-reg': '0.0', 'GdT-cell': '0.0', 'MAIT T-cell': '0.0', 'Memory CD4 T-cell': '0.0', 'Naive CD4 T-cell': '0.0', 'Memory CD8 T-cell': '0.0', 'Naive CD8 T-cell': '0.0', 'Memory B-cell': '0.0', 'Naive B-cell': '0.0', 'Plasmacytoid DC': '0.0', 'Myeloid DC': '0.0', 'NK-cell': '0.0', 'Total PBMC': '0.0', 'Vd2 gdTCR': '0.0', 'Memory CD4 T-cell Th1\\/Th17': '0.0', 'Memory CD4 T-cell Th17': '0.0', 'Memory CD4 T-cell Th2': '0.0', 'Non-Vd2 gdTCR': '0.0', 'Memory CD4 T-cell Th1': '0.0', 'Memory CD4 T-cell TFH': '0.0', 'Terminal effector memory CD4 T-cell': '0.0', 'Central memory CD8 T-cell': '0.0', 'Effector memory CD8 T-cell': '0.0', 'Terminal effector memory CD8 T-cell': '0.0', 'Non-switched memory B-cell': '0.0', 'Plasmablast': '0.0', 'Switched memory B-cell': '0.0', 'Exhausted memory B-cell': '0.0', 'Progenitor cell': '0.0', 'Memory T-reg': '0.0', 'Naive CD4 T-cell activated': '0.0', 'Naive CD8 T-cell activated': '0.0', 'Naive T-reg': '0.0'} | 2AHX, 2L2T, 2LCX, 2R4B, 3BBT, 3BBW, 3BCE, 3U2P, 3U7U, 3U9U, 8U4I, 8U4J, 8U4K, 8U4L | {'Adipose Tissue': 0.3812826387043189, 'Adrenal Gland': 0.1074241162790697, 'Bladder': 0.2619505238095238, 'Blood': 0.0089877201291711, 'Blood Vessel': 4.833504868913858, 'Brain': 6.451171196063588, 'Breast': 3.3113276209150326, 'Cervix Uteri': 1.0675215789473682, 'Colon': 0.1006024313222079, 'Esophagus': 0.0905226996539792, 'Fallopian Tube': 11.173333333333334, 'Heart': 1.5844851184668989, 'Kidney': 3.2344685393258428, 'Liver': 0.0179609336283185, 'Lung': 1.3194758650519032, 'Muscle': 0.8907386052303861, 'Nerve': 1.271967689822294, 'Ovary': 0.2119868333333333, 'Pancreas': 0.3690128048780488, 'Pituitary': 5.2564667844522965, 'Prostate': 0.3224207346938775, 'Salivary Gland': 2.7846685185185187, 'Skin': 0.3008394632393587, 'Small Intestine': 0.0590433636363636, 'Spleen': 0.0745424107883817, 'Stomach': 0.4317559721448468, 'Testis': 5.409421052631579, 'Thyroid': 2.26434134762634, 'Uterus': 0.1600107746478873, 'Vagina': 0.1911400769230769} | [39.93, 46.46, 52.9, 44.21, 41.4, 39.93, 35.91, 38.61, 36.44, 36.25, 34.86, 32.82, 32.01, 32.75, 31.69, 35.64, 36.35, 34.66, 33.32, 32.71, 35.01, 30.17, 37.05, 36.53, 48.19, 58.22, 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Forms a ternary complex composed of ADAM10, CADH1 and EPHA4, | null | null | KLRG1, SPEF1, DLGAP5, AJAP1, RAPGEF2, RAB8B, PIP5K1C, PKP2, TRPV4, CTNNB1, CAV1, DDR1, TBC1D2, CTNNA1, JUP, CTNND1, PSEN1, LIMA1, CDH1, JUP, ADAM10, CADH1 , EPHA4, | null | null | null | null | Homodimer | null | 79.91949 | 0.474025 | 73.038341 | 0.465153 | 258 |
P12830 | Q15398 | null | degron_data | CDH1 | MGPWSRSLSALLLLLQVSSWLCQEPEPCHPGFDAESYTFTVPRRHLERGRVLGRVNFEDCTGRQRTAYFSLDTRFKVGTDGVITVKRPLRFHNPQIHFLVYAWDSTYRKFSTKVTLNTVGHHHRPPPHQASVSGIQAELLTFPNSSPGLRRQKRDWVIPPISCPENEKGPFPKNLVQIKSNKDKEGKVFYSITGQGADTPPVGVFIIERETGWLKVTEPLDRERIATYTLFSHAVSSNGNAVEDPMEILITVTDQNDNKPEFTQEVFKGSVMEGALPGTSVMEVTATDADDDVNTYNAAIAYTILSQDPELPDKNMFTINRNTGVISVVTTGLDRESFPTYTLVVQAADLQGEGLSTTATAVITVTDTNDNPPIFNPTTYKGQVPENEANVVITTLKVTDADAPNTPAWEAVYTILNDDGGQFVVTTNPVNNDGILKTAKGLDFEAKQQYILHVAVTNVVPFEVSLTTSTATVTVDVLDVNEAPIFVPPEKRVEVSEDFGVGQEITSYTAQEPDTFMEQKITYRIWRDTANWLEINPDTGAISTRAELDREDFEHVKNSTYTALIIATDNGSPVATGTGTLLLILSDVNDNAPIPEPRTIFFCERNPKPQVINIIDADLPPNTSPFTAELTHGASANWTIQYNDPTQESIILKPKMALEVGDYKINLKLMDNQNKDQVTTLEVSVCDCEGAAGVCRKAQPVEAGLQIPAILGILGGILALLILILLLLLFLRRRAVVKEPLLPPEDDTRDNVYYYDEEGGGEEDQDFDLSQLHRGLDARPEVTRNDVAPTLMSVPRYLPRPANPDEIGNFIDENLKAADTDPTAPPYDSLLVFDYEGSGSEAASLSSLNSSESDKDQDYDYLNEWGNRFKKLADMYGGGEDD | Homo sapiens | Cell junction, adherens junction, Cell membrane, Endosome, Golgi apparatus, trans-Golgi network, Cytoplasm, Cell junction, desmosome | Tissue enhanced (parathyroid) | {'Ciliated cells': '119.1', 'Basal respiratory cells': '71.1', 'Club cells': '97.3', 'Ionocytes': '81.0', 'Mucus glandular cells': '155.0', 'Serous glandular cells': '67.8', 'Gastric mucus-secreting cells': '133.2', 'Proximal enterocytes': '140.9', 'Paneth cells': '125.1', 'Distal enterocytes': '307.5', 'Intestinal goblet cells': '173.5', 'Exocrine glandular cells': '-0.605', 'Basal prostatic cells': '68.3', 'Prostatic glandular cells': '186.7', 'Breast glandular cells': '0.773', 'Breast myoepithelial cells': '0.700', 'Glandular and luminal cells': '313.0', 'Secretory cells': '82.3', 'Basal keratinocytes': '102.5', 'Suprabasal keratinocytes': '162.6', 'Basal squamous epithelial cells': '51.0', 'Squamous epithelial cells': '106.9', 'Alveolar cells type 1': '0.437', 'Alveolar cells type 2': '0.706', 'Salivary duct cells': '95.9', 'Ductal cells': '0.541', 'Hepatocytes': '0.600', 'Cholangiocytes': '129.7', 'Proximal tubular cells': '0.042', 'Distal tubular cells': '0.0', 'Collecting duct cells': '143.9', 'Mesothelial cells': '0.799', 'Sertoli cells': '0.252', 'Granulosa cells': '12.9', 'Enteroendocrine cells': '92.4', 'Pancreatic endocrine cells': '78.1', 'Leydig cells': '0.264', 'Excitatory neurons': '0.7', 'Inhibitory neurons': '1.3', 'Cone photoreceptor cells': '0.0', 'Rod photoreceptor cells': '0.0', 'Bipolar cells': '0.2', 'Horizontal cells': '0.6', 'Astrocytes': '0.6', 'Oligodendrocyte precursor cells': '0.5', 'Oligodendrocytes': '29.9', 'Microglial cells': '0.9', 'Muller glia cells': '0.1', 'Schwann cells': '0.131', 'Spermatogonia': '0.392', 'Spermatocytes': '0.193', 'Early spermatids': '-0.217', 'Late spermatids': '-0.290', 'Oocytes': '16.9', 'Cytotrophoblasts': '119.2', 'Syncytiotrophoblasts': '45.0', 'Extravillous trophoblasts': '24.9', 'Endothelial cells': '6.1', 'Lymphatic endothelial cells': '0.4', 'Cardiomyocytes': '0.135', 'Skeletal myocytes': '0.107', 'Smooth muscle cells': '5.8', 'Adipocytes': '2.1', 'Melanocytes': '0.335', 'Fibroblasts': '6.5', 'Peritubular cells': '0.210', 'Endometrial stromal cells': '27.7', 'Ovarian stromal cells': '0.7', 'Undifferentiated cells': '101.6', 'T-cells': '2.9', 'B-cells': '4.4', 'Plasma cells': '6.1', 'Nk-cells': '0.0', 'Granulocytes': '8.4', 'Monocytes': '0.0', 'Macrophages': '6.0', 'Hofbauer cells': '4.3', 'Kupffer cells': '1.0', 'Dendritic cells': '5.9', 'Langerhans cells': '0.304', 'Erythroid cells': '0.036', 'Adipocytes (Subcutaneous)': '-0.081', 'Adipocytes (Visceral)': '-0.209', 'Breast glandular cells (progenitors)': '0.538', 'Adipocytes (Breast)': '-0.689', 'Colon enterocytes': '0.790', 'Colon enteroendocrine cells': '0.112', 'Enteric glia cells': '-0.048', 'Mitotic cells (Colon)': '0.299', 'Mitotic cells (Heart)': '0.120', 'Podocytes': '-0.118', 'Ascending Loop of Henle cells': '0.475', 'Intercalated cells': '0.212', 'Cholangiocyte': '0.090', 'NK-cells (Liver)': '-0.005', 'Respiratory ciliated cells': '-0.012', 'Mitotic cells (Lung)': '0.071', 'NK-cells (Lung)': '-0.266', 'B-cells (Lung)': '-0.296', 'Alpha cells': '0.270', 'Beta cells': '0.152', 'Prostate glandular cells': '0.764', 'Prostate basal glandular cells': '0.540', 'Urothelial cells': '0.205', 'Keratinocyte (other)': '0.510', 'Keratinocyte (granular)': '0.055', 'Hair cortex cells': '0.080', 'Inner root sheath cells': '0.131', 'Outer root sheath cells': '0.175', 'Sebaceous gland cells': '0.156', 'Eccrine sweat gland cells': '-0.207', 'Adipocytes (Skin)': '-0.244', 'Mitotic cells (Skin)': '0.442', 'Parietal cells': '0.654', 'Chief cells': '0.649', 'Gastric mucous cells': '0.781', 'Gastric enteroendocrine cells': '0.590', 'Mitotic cells (Stomach)': '0.445', 'Parafollicular cells': '0.173', 'Thyroid glandular cells': '0.865', 'Mitotic cells (Thyroid)': '-0.081', 'Adrenal cortex cells': '0.051', 'Adrenal medulla cells': '0.087', 'Mitotic cells (Adrenal gland)': '0.072', 'Minor salivary glandular cells': '0.371', 'Minor salivary gland ductal cells': '-0.142', 'Minor salivary gland basal cells': '0.582', 'Mitotic cells (Minor salivary gland)': '0.567', 'Adipocytes (Minor salivary gland)': '0.050', 'Somatotropes': '0.121', 'Lactotropes': '0.322', 'Gonadotropes': '0.330', 'Corticotropes': '0.180', 'Thyrotropes': '0.496', 'Undifferentiated cells (Pituitary gland)': '-0.108', 'Mitotic cells (Spleen)': '-0.228', 'Platelets': '-0.050', 'Erythrocytes': '-0.158', 'Hematopoietic stem cells': '-0.211', 'B-cells (Spleen)': '0.266', 'NK-cells (Spleen)': '0.309', 'Amygdala excitatory': '1.0', 'Cerebellar inhibitory': '0.9', 'Cge interneuron': '0.7', 'Deep-layer corticothalamic and 6b': '1.5', 'Deep-layer intratelencephalic': '0.7', 'Deep-layer near-projecting': '0.7', 'Eccentric medium spiny neuron': '0.6', 'Hippocampal ca1-3': '1.9', 'Hippocampal ca4': '1.2', 'Hippocampal dentate gyrus': '1.1', 'Lamp5-lhx6 and chandelier': '0.5', 'Lower rhombic lip': '0.8', 'Mammillary body': '0.6', 'Medium spiny neuron': '0.7', 'Mge interneuron': '1.7', 'Midbrain-derived inhibitory': '0.7', 'Miscellaneous': '0.9', 'Splatter': '3.8', 'Thalamic excitatory': '0.5', 'Upper rhombic lip': '0.8', 'Upper-layer intratelencephalic': '0.6', 'Astrocyte': '4.4', 'Bergmann glia': '0.2', 'Central nervous system macrophage': '0.6', 'Choroid plexus epithelial cell': '52.1', 'Committed oligodendrocyte precursor': '41.5', 'Ependymal cell': '4.8', 'Oligodendrocyte': '53.1', 'Oligodendrocyte precursor cell': '2.4', 'Endothelial cell': '0.7', 'Pericyte': '0.3', 'Vascular associated smooth muscle cell': '0.0', 'Fibroblast': '17.4', 'Leukocyte': '1.1', 'Basophil': '0.0', 'Eosinophil': '0.0', 'Neutrophil': '0.0', 'Classical monocyte': '0.0', 'Non-classical monocyte': '0.0', 'Intermediate monocyte': '0.0', 'T-reg': '2.3', 'GdT-cell': '0.0', 'MAIT T-cell': '0.0', 'Memory CD4 T-cell': '0.0', 'Naive CD4 T-cell': '0.1', 'Memory CD8 T-cell': '0.2', 'Naive CD8 T-cell': '0.3', 'Memory B-cell': '0.0', 'Naive B-cell': '0.1', 'Plasmacytoid DC': '46.6', 'Myeloid DC': '8.5', 'NK-cell': '0.1', 'Total PBMC': '0.7', 'Vd2 gdTCR': '0.0', 'Memory CD4 T-cell Th1\\/Th17': '0.1', 'Memory CD4 T-cell Th17': '0.2', 'Memory CD4 T-cell Th2': '2.9', 'Non-Vd2 gdTCR': '0.1', 'Memory CD4 T-cell Th1': '0.3', 'Memory CD4 T-cell TFH': '0.5', 'Terminal effector memory CD4 T-cell': '0.0', 'Central memory CD8 T-cell': '4.8', 'Effector memory CD8 T-cell': '0.0', 'Terminal effector memory CD8 T-cell': '0.6', 'Non-switched memory B-cell': '0.0', 'Plasmablast': '3.3', 'Switched memory B-cell': '0.0', 'Exhausted memory B-cell': '0.7', 'Progenitor cell': '2.3', 'Memory T-reg': '1.3', 'Naive CD4 T-cell activated': '0.3', 'Naive CD8 T-cell activated': '0.6', 'Naive T-reg': '0.1'} | 1O6S, 2O72, 2OMT, 2OMU, 2OMV, 2OMX, 2OMY, 2OMZ, 3FF7, 3FF8, 3L6X, 3L6Y, 4ZT1, 4ZTE, 6CXY, 6OLE, 6OLF, 6OLG, 6VEL, 7STZ, 8H62 | {'Adipose Tissue': 1.2125261088039867, 'Adrenal Gland': 0.1914223992248062, 'Bladder': 39.2033519047619, 'Blood': 1.340954264800861, 'Blood Vessel': 0.3121561692883895, 'Brain': 0.8550442199091597, 'Breast': 38.54918344226579, 'Cervix Uteri': 23.539115789473684, 'Colon': 43.41292142490372, 'Esophagus': 53.97513367404844, 'Fallopian Tube': 14.900277777777776, 'Heart': 0.119140469221835, 'Kidney': 25.040449438202245, 'Liver': 26.60802654867257, 'Lung': 35.447986366782004, 'Muscle': 0.1378936151930261, 'Nerve': 17.518468982229404, 'Ovary': 3.6515122222222223, 'Pancreas': 56.89676829268293, 'Pituitary': 24.68741660777385, 'Prostate': 61.279967346938776, 'Salivary Gland': 92.01685185185184, 'Skin': 79.77571720232172, 'Small Intestine': 71.7519320855615, 'Spleen': 10.061029045643156, 'Stomach': 58.07813805013927, 'Testis': 0.8144204986149585, 'Thyroid': 135.176797856049, 'Uterus': 1.442593943661972, 'Vagina': 86.52345512820513} | DLGAP5 | MSSSHFASRHRKDISTEMIRTKIAHRKSLSQKENRHKEYERNRHFGLKDVNIPTLEGRILVELDETSQGLVPEKTNVKPRAMKTILGDQRKQMLQKYKEEKQLQKLKEQREKAKRGIFKVGRYRPDMPCFLLSNQNAVKAEPKKAIPSSVRITRSKAKDQMEQTKIDNESDVRAIRPGPRQTSEKKVSDKEKKVVQPVMPTSLRMTRSATQAAKQVPRTVSSTTARKPVTRAANENEPEGKVPSKGRPAKNVETKPDKGISCKVDSEENTLNSQTNATSGMNPDGVLSKMENLPEINTAKIKGKNSFAPKDFMFQPLDGLKTYQVTPMTPRSANAFLTPSYTWTPLKTEVDESQATKEILAQKCKTYSTKTIQQDSNKLPCPLGPLTVWHEEHVLNKNEATTKNLNGLPIKEVPSLERNEGRIAQPHHGVPYFRNILQSETEKLTSHCFEWDRKLELDIPDDAKDLIRTAVGQTRLLMKERFKQFEGLVDDCEYKRGIKETTCTDLDGFWDMVSFQIEDVIHKFNNLIKLEESGWQVNNNMNHNMNKNVFRKKVVSGIASKPKQDDAGRIAARNRLAAIKNAMRERIRQEECAETAVSVIPKEVDKIVFDAGFFRVESPVKLFSGLSVSSEGPSQRLGTPKSVNKAVSQSRNEMGIPQQTTSPENAGPQNTKSEHVKKTLFLSIPESRSSIEDAQCPGLPDLIEENHVVNKTDLKVDCLSSERMSLPLLAGGVADDINTNKKEGISDVVEGMELNSSITSQDVLMSSPEKNTASQNSILEEGETKISQSELFDNKSLTTECHLLDSPGLNCSNPFTQLERRHQEHARHISFGGNLITFSPLQPGEF | Homo sapiens | Nucleus, Cytoplasm, Cytoplasm, cytoskeleton, spindle | Group enriched (bone marrow, lymphoid tissue, testis) | {'Ciliated cells': '4.1', 'Basal respiratory cells': '3.3', 'Club cells': '1.6', 'Ionocytes': '0.7', 'Mucus glandular cells': '1.3', 'Serous glandular cells': '2.4', 'Gastric mucus-secreting cells': '8.8', 'Proximal enterocytes': '0.2', 'Paneth cells': '0.2', 'Distal enterocytes': '0.1', 'Intestinal goblet cells': '4.4', 'Exocrine glandular cells': '-0.249', 'Basal prostatic cells': '0.0', 'Prostatic glandular cells': '0.1', 'Breast glandular cells': '0.118', 'Breast myoepithelial cells': '0.219', 'Glandular and luminal cells': '4.7', 'Secretory cells': '0.5', 'Basal keratinocytes': '8.5', 'Suprabasal keratinocytes': '2.2', 'Basal squamous epithelial cells': '1.3', 'Squamous epithelial cells': '11.7', 'Alveolar cells type 1': '-0.264', 'Alveolar cells type 2': '0.095', 'Salivary duct cells': '1.3', 'Ductal cells': '0.447', 'Hepatocytes': '0.286', 'Cholangiocytes': '0.0', 'Proximal tubular cells': '0.295', 'Distal tubular cells': '0.0', 'Collecting duct cells': '0.0', 'Mesothelial cells': '0.010', 'Sertoli cells': '-0.239', 'Granulosa cells': '11.8', 'Enteroendocrine cells': '0.8', 'Pancreatic endocrine cells': '6.8', 'Leydig cells': '-0.201', 'Excitatory neurons': '0.3', 'Inhibitory neurons': '0.3', 'Cone photoreceptor cells': '0.0', 'Rod photoreceptor cells': '0.0', 'Bipolar cells': '0.0', 'Horizontal cells': '0.0', 'Astrocytes': '0.0', 'Oligodendrocyte precursor cells': '0.0', 'Oligodendrocytes': '0.3', 'Microglial cells': '0.0', 'Muller glia cells': '0.0', 'Schwann cells': '0.125', 'Spermatogonia': '0.213', 'Spermatocytes': '0.688', 'Early spermatids': '0.692', 'Late spermatids': '0.222', 'Oocytes': '355.1', 'Cytotrophoblasts': '12.0', 'Syncytiotrophoblasts': '1.5', 'Extravillous trophoblasts': '23.4', 'Endothelial cells': '1.2', 'Lymphatic endothelial cells': '0.1', 'Cardiomyocytes': '0.241', 'Skeletal myocytes': '0.031', 'Smooth muscle cells': '1.6', 'Adipocytes': '0.1', 'Melanocytes': '0.482', 'Fibroblasts': '2.7', 'Peritubular cells': '-0.201', 'Endometrial stromal cells': '1.8', 'Ovarian stromal cells': '1.1', 'Undifferentiated cells': '15.5', 'T-cells': '3.3', 'B-cells': '1.0', 'Plasma cells': '26.4', 'Nk-cells': '1.3', 'Granulocytes': '0.0', 'Monocytes': '0.0', 'Macrophages': '3.6', 'Hofbauer cells': '8.1', 'Kupffer cells': '2.9', 'Dendritic cells': '0.0', 'Langerhans cells': '0.148', 'Erythroid cells': '0.229', 'Adipocytes (Subcutaneous)': '-0.092', 'Adipocytes (Visceral)': '-0.119', 'Breast glandular cells (progenitors)': '0.193', 'Adipocytes (Breast)': '-0.080', 'Colon enterocytes': '0.318', 'Colon enteroendocrine cells': '-0.132', 'Enteric glia cells': '-0.212', 'Mitotic cells (Colon)': '0.747', 'Mitotic cells (Heart)': '0.758', 'Podocytes': '-0.091', 'Ascending Loop of Henle cells': '0.129', 'Intercalated cells': '-0.141', 'Cholangiocyte': '0.280', 'NK-cells (Liver)': '-0.073', 'Respiratory ciliated cells': '0.011', 'Mitotic cells (Lung)': '0.883', 'NK-cells (Lung)': '-0.078', 'B-cells (Lung)': '0.062', 'Alpha cells': '0.116', 'Beta cells': '0.006', 'Prostate glandular cells': '-0.109', 'Prostate basal glandular cells': '0.127', 'Urothelial cells': '0.168', 'Keratinocyte (other)': '0.209', 'Keratinocyte (granular)': '-0.238', 'Hair cortex cells': '0.180', 'Inner root sheath cells': '0.346', 'Outer root sheath cells': '0.346', 'Sebaceous gland cells': '0.098', 'Eccrine sweat gland cells': '0.037', 'Adipocytes (Skin)': '-0.094', 'Mitotic cells (Skin)': '0.909', 'Parietal cells': '0.212', 'Chief cells': '0.172', 'Gastric mucous cells': '0.606', 'Gastric enteroendocrine cells': '0.266', 'Mitotic cells (Stomach)': '0.916', 'Parafollicular cells': '-0.062', 'Thyroid glandular cells': '-0.119', 'Mitotic cells (Thyroid)': '0.783', 'Adrenal cortex cells': '0.459', 'Adrenal medulla cells': '0.140', 'Mitotic cells (Adrenal gland)': '0.940', 'Minor salivary glandular cells': '0.113', 'Minor salivary gland ductal cells': '-0.327', 'Minor salivary gland basal cells': '0.651', 'Mitotic cells (Minor salivary gland)': '0.956', 'Adipocytes (Minor salivary gland)': '0.133', 'Somatotropes': '-0.175', 'Lactotropes': '-0.168', 'Gonadotropes': '-0.137', 'Corticotropes': '-0.197', 'Thyrotropes': '-0.127', 'Undifferentiated cells (Pituitary gland)': '0.282', 'Mitotic cells (Spleen)': '0.948', 'Platelets': '0.193', 'Erythrocytes': '0.329', 'Hematopoietic stem cells': '0.399', 'B-cells (Spleen)': '-0.134', 'NK-cells (Spleen)': '-0.237', 'Amygdala excitatory': '0.2', 'Cerebellar inhibitory': '0.2', 'Cge interneuron': '0.2', 'Deep-layer corticothalamic and 6b': '0.2', 'Deep-layer intratelencephalic': '0.3', 'Deep-layer near-projecting': '0.3', 'Eccentric medium spiny neuron': '0.3', 'Hippocampal ca1-3': '0.1', 'Hippocampal ca4': '0.4', 'Hippocampal dentate gyrus': '0.3', 'Lamp5-lhx6 and chandelier': '0.2', 'Lower rhombic lip': '0.2', 'Mammillary body': '0.2', 'Medium spiny neuron': '0.3', 'Mge interneuron': '0.3', 'Midbrain-derived inhibitory': '0.2', 'Miscellaneous': '0.2', 'Splatter': '0.2', 'Thalamic excitatory': '0.4', 'Upper rhombic 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Forms a ternary complex composed of ADAM10, CADH1 and EPHA4, | null | null | KLRG1, SPEF1, DLGAP5, AJAP1, RAPGEF2, RAB8B, PIP5K1C, PKP2, TRPV4, CTNNB1, CAV1, DDR1, TBC1D2, CTNNA1, JUP, CTNND1, PSEN1, LIMA1, CDH1, JUP, ADAM10, CADH1 , EPHA4, | null | null | null | null | Homodimer | null | 79.91949 | 0.474025 | 55.445307 | 0.80143 | 732 |
P12830 | Q15468 | null | degron_data | CDH1 | MGPWSRSLSALLLLLQVSSWLCQEPEPCHPGFDAESYTFTVPRRHLERGRVLGRVNFEDCTGRQRTAYFSLDTRFKVGTDGVITVKRPLRFHNPQIHFLVYAWDSTYRKFSTKVTLNTVGHHHRPPPHQASVSGIQAELLTFPNSSPGLRRQKRDWVIPPISCPENEKGPFPKNLVQIKSNKDKEGKVFYSITGQGADTPPVGVFIIERETGWLKVTEPLDRERIATYTLFSHAVSSNGNAVEDPMEILITVTDQNDNKPEFTQEVFKGSVMEGALPGTSVMEVTATDADDDVNTYNAAIAYTILSQDPELPDKNMFTINRNTGVISVVTTGLDRESFPTYTLVVQAADLQGEGLSTTATAVITVTDTNDNPPIFNPTTYKGQVPENEANVVITTLKVTDADAPNTPAWEAVYTILNDDGGQFVVTTNPVNNDGILKTAKGLDFEAKQQYILHVAVTNVVPFEVSLTTSTATVTVDVLDVNEAPIFVPPEKRVEVSEDFGVGQEITSYTAQEPDTFMEQKITYRIWRDTANWLEINPDTGAISTRAELDREDFEHVKNSTYTALIIATDNGSPVATGTGTLLLILSDVNDNAPIPEPRTIFFCERNPKPQVINIIDADLPPNTSPFTAELTHGASANWTIQYNDPTQESIILKPKMALEVGDYKINLKLMDNQNKDQVTTLEVSVCDCEGAAGVCRKAQPVEAGLQIPAILGILGGILALLILILLLLLFLRRRAVVKEPLLPPEDDTRDNVYYYDEEGGGEEDQDFDLSQLHRGLDARPEVTRNDVAPTLMSVPRYLPRPANPDEIGNFIDENLKAADTDPTAPPYDSLLVFDYEGSGSEAASLSSLNSSESDKDQDYDYLNEWGNRFKKLADMYGGGEDD | Homo sapiens | Cell junction, adherens junction, Cell membrane, Endosome, Golgi apparatus, trans-Golgi network, Cytoplasm, Cell junction, desmosome | Tissue enhanced (parathyroid) | {'Ciliated cells': '119.1', 'Basal respiratory cells': '71.1', 'Club cells': '97.3', 'Ionocytes': '81.0', 'Mucus glandular cells': '155.0', 'Serous glandular cells': '67.8', 'Gastric mucus-secreting cells': '133.2', 'Proximal enterocytes': '140.9', 'Paneth cells': '125.1', 'Distal enterocytes': '307.5', 'Intestinal goblet cells': '173.5', 'Exocrine glandular cells': '-0.605', 'Basal prostatic cells': '68.3', 'Prostatic glandular cells': '186.7', 'Breast glandular cells': '0.773', 'Breast myoepithelial cells': '0.700', 'Glandular and luminal cells': '313.0', 'Secretory cells': '82.3', 'Basal keratinocytes': '102.5', 'Suprabasal keratinocytes': '162.6', 'Basal squamous epithelial cells': '51.0', 'Squamous epithelial cells': '106.9', 'Alveolar cells type 1': '0.437', 'Alveolar cells type 2': '0.706', 'Salivary duct cells': '95.9', 'Ductal cells': '0.541', 'Hepatocytes': '0.600', 'Cholangiocytes': '129.7', 'Proximal tubular cells': '0.042', 'Distal tubular cells': '0.0', 'Collecting duct cells': '143.9', 'Mesothelial cells': '0.799', 'Sertoli cells': '0.252', 'Granulosa cells': '12.9', 'Enteroendocrine cells': '92.4', 'Pancreatic endocrine cells': '78.1', 'Leydig cells': '0.264', 'Excitatory neurons': '0.7', 'Inhibitory neurons': '1.3', 'Cone photoreceptor cells': '0.0', 'Rod photoreceptor cells': '0.0', 'Bipolar cells': '0.2', 'Horizontal cells': '0.6', 'Astrocytes': '0.6', 'Oligodendrocyte precursor cells': '0.5', 'Oligodendrocytes': '29.9', 'Microglial cells': '0.9', 'Muller glia cells': '0.1', 'Schwann cells': '0.131', 'Spermatogonia': '0.392', 'Spermatocytes': '0.193', 'Early spermatids': '-0.217', 'Late spermatids': '-0.290', 'Oocytes': '16.9', 'Cytotrophoblasts': '119.2', 'Syncytiotrophoblasts': '45.0', 'Extravillous trophoblasts': '24.9', 'Endothelial cells': '6.1', 'Lymphatic endothelial cells': '0.4', 'Cardiomyocytes': '0.135', 'Skeletal myocytes': '0.107', 'Smooth muscle cells': '5.8', 'Adipocytes': '2.1', 'Melanocytes': '0.335', 'Fibroblasts': '6.5', 'Peritubular cells': '0.210', 'Endometrial stromal cells': '27.7', 'Ovarian stromal cells': '0.7', 'Undifferentiated cells': '101.6', 'T-cells': '2.9', 'B-cells': '4.4', 'Plasma cells': '6.1', 'Nk-cells': '0.0', 'Granulocytes': '8.4', 'Monocytes': '0.0', 'Macrophages': '6.0', 'Hofbauer cells': '4.3', 'Kupffer cells': '1.0', 'Dendritic cells': '5.9', 'Langerhans cells': '0.304', 'Erythroid cells': '0.036', 'Adipocytes (Subcutaneous)': '-0.081', 'Adipocytes (Visceral)': '-0.209', 'Breast glandular cells (progenitors)': '0.538', 'Adipocytes (Breast)': '-0.689', 'Colon enterocytes': '0.790', 'Colon enteroendocrine cells': '0.112', 'Enteric glia cells': '-0.048', 'Mitotic cells (Colon)': '0.299', 'Mitotic cells (Heart)': '0.120', 'Podocytes': '-0.118', 'Ascending Loop of Henle cells': '0.475', 'Intercalated cells': '0.212', 'Cholangiocyte': '0.090', 'NK-cells (Liver)': '-0.005', 'Respiratory ciliated cells': '-0.012', 'Mitotic cells (Lung)': '0.071', 'NK-cells (Lung)': '-0.266', 'B-cells (Lung)': '-0.296', 'Alpha cells': '0.270', 'Beta cells': '0.152', 'Prostate glandular cells': '0.764', 'Prostate basal glandular cells': '0.540', 'Urothelial cells': '0.205', 'Keratinocyte (other)': '0.510', 'Keratinocyte (granular)': '0.055', 'Hair cortex cells': '0.080', 'Inner root sheath cells': '0.131', 'Outer root sheath cells': '0.175', 'Sebaceous gland cells': '0.156', 'Eccrine sweat gland cells': '-0.207', 'Adipocytes (Skin)': '-0.244', 'Mitotic cells (Skin)': '0.442', 'Parietal cells': '0.654', 'Chief cells': '0.649', 'Gastric mucous cells': '0.781', 'Gastric enteroendocrine cells': '0.590', 'Mitotic cells (Stomach)': '0.445', 'Parafollicular cells': '0.173', 'Thyroid glandular cells': '0.865', 'Mitotic cells (Thyroid)': '-0.081', 'Adrenal cortex cells': '0.051', 'Adrenal medulla cells': '0.087', 'Mitotic cells (Adrenal gland)': '0.072', 'Minor salivary glandular cells': '0.371', 'Minor salivary gland ductal cells': '-0.142', 'Minor salivary gland basal cells': '0.582', 'Mitotic cells (Minor salivary gland)': '0.567', 'Adipocytes (Minor salivary gland)': '0.050', 'Somatotropes': '0.121', 'Lactotropes': '0.322', 'Gonadotropes': '0.330', 'Corticotropes': '0.180', 'Thyrotropes': '0.496', 'Undifferentiated cells (Pituitary gland)': '-0.108', 'Mitotic cells (Spleen)': '-0.228', 'Platelets': '-0.050', 'Erythrocytes': '-0.158', 'Hematopoietic stem cells': '-0.211', 'B-cells (Spleen)': '0.266', 'NK-cells (Spleen)': '0.309', 'Amygdala excitatory': '1.0', 'Cerebellar inhibitory': '0.9', 'Cge interneuron': '0.7', 'Deep-layer corticothalamic and 6b': '1.5', 'Deep-layer intratelencephalic': '0.7', 'Deep-layer near-projecting': '0.7', 'Eccentric medium spiny neuron': '0.6', 'Hippocampal ca1-3': '1.9', 'Hippocampal ca4': '1.2', 'Hippocampal dentate gyrus': '1.1', 'Lamp5-lhx6 and chandelier': '0.5', 'Lower rhombic lip': '0.8', 'Mammillary body': '0.6', 'Medium spiny neuron': '0.7', 'Mge interneuron': '1.7', 'Midbrain-derived inhibitory': '0.7', 'Miscellaneous': '0.9', 'Splatter': '3.8', 'Thalamic excitatory': '0.5', 'Upper rhombic lip': '0.8', 'Upper-layer intratelencephalic': '0.6', 'Astrocyte': '4.4', 'Bergmann glia': '0.2', 'Central nervous system macrophage': '0.6', 'Choroid plexus epithelial cell': '52.1', 'Committed oligodendrocyte precursor': '41.5', 'Ependymal cell': '4.8', 'Oligodendrocyte': '53.1', 'Oligodendrocyte precursor cell': '2.4', 'Endothelial cell': '0.7', 'Pericyte': '0.3', 'Vascular associated smooth muscle cell': '0.0', 'Fibroblast': '17.4', 'Leukocyte': '1.1', 'Basophil': '0.0', 'Eosinophil': '0.0', 'Neutrophil': '0.0', 'Classical monocyte': '0.0', 'Non-classical monocyte': '0.0', 'Intermediate monocyte': '0.0', 'T-reg': '2.3', 'GdT-cell': '0.0', 'MAIT T-cell': '0.0', 'Memory CD4 T-cell': '0.0', 'Naive CD4 T-cell': '0.1', 'Memory CD8 T-cell': '0.2', 'Naive CD8 T-cell': '0.3', 'Memory B-cell': '0.0', 'Naive B-cell': '0.1', 'Plasmacytoid DC': '46.6', 'Myeloid DC': '8.5', 'NK-cell': '0.1', 'Total PBMC': '0.7', 'Vd2 gdTCR': '0.0', 'Memory CD4 T-cell Th1\\/Th17': '0.1', 'Memory CD4 T-cell Th17': '0.2', 'Memory CD4 T-cell Th2': '2.9', 'Non-Vd2 gdTCR': '0.1', 'Memory CD4 T-cell Th1': '0.3', 'Memory CD4 T-cell TFH': '0.5', 'Terminal effector memory CD4 T-cell': '0.0', 'Central memory CD8 T-cell': '4.8', 'Effector memory CD8 T-cell': '0.0', 'Terminal effector memory CD8 T-cell': '0.6', 'Non-switched memory B-cell': '0.0', 'Plasmablast': '3.3', 'Switched memory B-cell': '0.0', 'Exhausted memory B-cell': '0.7', 'Progenitor cell': '2.3', 'Memory T-reg': '1.3', 'Naive CD4 T-cell activated': '0.3', 'Naive CD8 T-cell activated': '0.6', 'Naive T-reg': '0.1'} | 1O6S, 2O72, 2OMT, 2OMU, 2OMV, 2OMX, 2OMY, 2OMZ, 3FF7, 3FF8, 3L6X, 3L6Y, 4ZT1, 4ZTE, 6CXY, 6OLE, 6OLF, 6OLG, 6VEL, 7STZ, 8H62 | {'Adipose Tissue': 1.2125261088039867, 'Adrenal Gland': 0.1914223992248062, 'Bladder': 39.2033519047619, 'Blood': 1.340954264800861, 'Blood Vessel': 0.3121561692883895, 'Brain': 0.8550442199091597, 'Breast': 38.54918344226579, 'Cervix Uteri': 23.539115789473684, 'Colon': 43.41292142490372, 'Esophagus': 53.97513367404844, 'Fallopian Tube': 14.900277777777776, 'Heart': 0.119140469221835, 'Kidney': 25.040449438202245, 'Liver': 26.60802654867257, 'Lung': 35.447986366782004, 'Muscle': 0.1378936151930261, 'Nerve': 17.518468982229404, 'Ovary': 3.6515122222222223, 'Pancreas': 56.89676829268293, 'Pituitary': 24.68741660777385, 'Prostate': 61.279967346938776, 'Salivary Gland': 92.01685185185184, 'Skin': 79.77571720232172, 'Small Intestine': 71.7519320855615, 'Spleen': 10.061029045643156, 'Stomach': 58.07813805013927, 'Testis': 0.8144204986149585, 'Thyroid': 135.176797856049, 'Uterus': 1.442593943661972, 'Vagina': 86.52345512820513} | STIL | MEPIYPFARPQMNTRFPSSRMVPFHFPPSKCALWNPTPTGDFIYLHLSYYRNPKLVVTEKTIRLAYRHAKQNKKNSSCFLLGSLTADEDEEGVTLTVDRFDPGREVPECLEITPTASLPGDFLIPCKVHTQELCSREMIVHSVDDFSSALKALQCHICSKDSLDCGKLLSLRVHITSRESLDSVEFDLHWAAVTLANNFKCTPVKPIPIIPTALARNLSSNLNISQVQGTYKYGYLTMDETRKLLLLLESDPKVYSLPLVGIWLSGITHIYSPQVWACCLRYIFNSSVQERVFSESGNFIIVLYSMTHKEPEFYECFPCDGKIPDFRFQLLTSKETLHLFKNVEPPDKNPIRCELSAESQNAETEFFSKASKNFSIKRSSQKLSSGKMPIHDHDSGVEDEDFSPRPIPSPHPVSQKISKIQPSVPELSLVLDGNFIESNPLPTPLEMVNNENPPLINHLEHLKPLQPQLYDEKHSPEVEAGEPSLRGIPNQLNQDKPALLRHCKVRQPPAYKKGNPHTRNSIKPSSHNGPSHDIFEKLQTVSAGNVQNEEYPIRPSTLNSRQSSLAPQSQPHDFVFSPHNSGRPMELQIPTPPLPSYCSTNVCRCCQHHSHIQYSPLNSWQGANTVGSIQDVQSEALQKHSLFHPSGCPALYCNAFCSSSSPIALRPQGDMGSCSPHSNIEPSPVARPPSHMDLCNPQPCTVCMHTPKTESDNGMMGLSPDAYRFLTEQDRQLRLLQAQIQRLLEAQSLMPCSPKTTAVEDTVQAGRQMELVSVEAQSSPGLHMRKGVSIAVSTGASLFWNAAGEDQEPDSQMKQDDTKISSEDMNFSVDINNEVTSLPGSASSLKAVDIPSFEESNIAVEEEFNQPLSVSNSSLVVRKEPDVPVFFPSGQLAESVSMCLQTGPTGGASNNSETSEEPKIEHVMQPLLHQPSDNQKIYQDLLGQVNHLLNSSSKETEQPSTKAVIISHECTRTQNVYHTKKKTHHSRLVDKDCVLNATLKQLRSLGVKIDSPTKVKKNAHNVDHASVLACISPEAVISGLNCMSFANVGMSGLSPNGVDLSMEANAIALKYLNENQLSQLSVTRSNQNNCDPFSLLHINTDRSTVGLSLISPNNMSFATKKYMKRYGLLQSSDNSEDEEEPPDNADSKSEYLLNQNLRSIPEQLGGQKEPSKNDHEIINCSNCESVGTNADTPVLRNITNEVLQTKAKQQLTEKPAFLVKNLKPSPAVNLRTGKAEFTQHPEKENEGDITIFPESLQPSETLKQMNSMNSVGTFLDVKRLRQLPKLF | Homo sapiens | Cytoplasm, cytosol, Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriole, Cytoplasm, cell cortex | Tissue enhanced (bone marrow, lymphoid tissue) | {'Ciliated cells': '6.1', 'Basal respiratory cells': '1.7', 'Club cells': '2.0', 'Ionocytes': '2.2', 'Mucus glandular cells': '5.8', 'Serous glandular cells': '3.3', 'Gastric mucus-secreting cells': '4.1', 'Proximal enterocytes': '1.3', 'Paneth cells': '1.6', 'Distal enterocytes': '3.9', 'Intestinal goblet cells': '4.7', 'Exocrine glandular cells': '-0.580', 'Basal prostatic cells': '0.6', 'Prostatic glandular cells': '1.2', 'Breast glandular cells': '0.533', 'Breast myoepithelial cells': '0.393', 'Glandular and luminal cells': '12.1', 'Secretory cells': '1.1', 'Basal keratinocytes': '3.0', 'Suprabasal keratinocytes': '2.5', 'Basal squamous epithelial cells': '2.2', 'Squamous epithelial cells': '5.5', 'Alveolar cells type 1': '-0.234', 'Alveolar cells type 2': '0.152', 'Salivary duct cells': '3.0', 'Ductal cells': '0.637', 'Hepatocytes': '0.347', 'Cholangiocytes': '0.0', 'Proximal tubular cells': '0.279', 'Distal tubular cells': '0.0', 'Collecting duct cells': '0.0', 'Mesothelial cells': '-0.075', 'Sertoli cells': '-0.106', 'Granulosa cells': '1.7', 'Enteroendocrine cells': '1.1', 'Pancreatic endocrine cells': '3.4', 'Leydig cells': '-0.087', 'Excitatory neurons': '4.9', 'Inhibitory neurons': '3.8', 'Cone photoreceptor cells': '0.0', 'Rod photoreceptor cells': '1.1', 'Bipolar cells': '0.4', 'Horizontal cells': '1.3', 'Astrocytes': '1.9', 'Oligodendrocyte precursor cells': '1.9', 'Oligodendrocytes': '4.5', 'Microglial cells': '0.0', 'Muller glia cells': '0.4', 'Schwann cells': '0.101', 'Spermatogonia': '0.308', 'Spermatocytes': '0.794', 'Early spermatids': '0.443', 'Late spermatids': '0.025', 'Oocytes': '1.5', 'Cytotrophoblasts': '2.5', 'Syncytiotrophoblasts': '0.8', 'Extravillous trophoblasts': '4.3', 'Endothelial cells': '1.3', 'Lymphatic endothelial cells': '6.0', 'Cardiomyocytes': '0.354', 'Skeletal myocytes': '-0.023', 'Smooth muscle cells': '1.1', 'Adipocytes': '1.2', 'Melanocytes': '0.348', 'Fibroblasts': '1.0', 'Peritubular cells': '-0.098', 'Endometrial stromal cells': '2.6', 'Ovarian stromal cells': '0.4', 'Undifferentiated cells': '9.6', 'T-cells': '2.7', 'B-cells': '2.4', 'Plasma cells': '9.5', 'Nk-cells': '1.6', 'Granulocytes': '0.3', 'Monocytes': '0.9', 'Macrophages': '2.6', 'Hofbauer cells': '2.5', 'Kupffer cells': '2.0', 'Dendritic cells': '1.6', 'Langerhans cells': '0.340', 'Erythroid cells': '-0.128', 'Adipocytes (Subcutaneous)': '0.098', 'Adipocytes (Visceral)': '0.066', 'Breast glandular cells (progenitors)': '0.430', 'Adipocytes (Breast)': '-0.438', 'Colon enterocytes': '0.454', 'Colon enteroendocrine cells': '0.025', 'Enteric glia cells': '-0.146', 'Mitotic cells (Colon)': '0.570', 'Mitotic cells (Heart)': '0.653', 'Podocytes': '-0.273', 'Ascending Loop of Henle cells': '0.351', 'Intercalated cells': '-0.213', 'Cholangiocyte': '0.326', 'NK-cells (Liver)': '-0.225', 'Respiratory ciliated cells': '0.142', 'Mitotic cells (Lung)': '0.705', 'NK-cells (Lung)': '-0.146', 'B-cells (Lung)': '-0.029', 'Alpha cells': '0.334', 'Beta cells': '0.246', 'Prostate glandular cells': '0.421', 'Prostate basal glandular cells': '0.450', 'Urothelial cells': '0.255', 'Keratinocyte (other)': '0.446', 'Keratinocyte (granular)': '-0.069', 'Hair cortex cells': '-0.168', 'Inner root sheath cells': '-0.064', 'Outer root sheath cells': '0.044', 'Sebaceous gland cells': '0.111', 'Eccrine sweat gland cells': '-0.211', 'Adipocytes (Skin)': '-0.371', 'Mitotic cells (Skin)': '0.624', 'Parietal cells': '0.239', 'Chief cells': '0.170', 'Gastric mucous cells': '0.662', 'Gastric enteroendocrine cells': '0.307', 'Mitotic cells (Stomach)': '0.832', 'Parafollicular cells': '0.014', 'Thyroid glandular cells': '0.140', 'Mitotic cells (Thyroid)': '0.343', 'Adrenal cortex cells': '0.364', 'Adrenal medulla cells': '0.085', 'Mitotic cells (Adrenal gland)': '0.751', 'Minor salivary glandular cells': '0.244', 'Minor salivary gland ductal cells': '0.100', 'Minor salivary gland basal cells': '-0.021', 'Mitotic cells (Minor salivary gland)': '0.070', 'Adipocytes (Minor salivary gland)': '-0.282', 'Somatotropes': '-0.092', 'Lactotropes': '-0.241', 'Gonadotropes': '-0.016', 'Corticotropes': '-0.256', 'Thyrotropes': '-0.094', 'Undifferentiated cells (Pituitary gland)': '0.452', 'Mitotic cells (Spleen)': '0.831', 'Platelets': '0.137', 'Erythrocytes': '0.313', 'Hematopoietic stem cells': '0.223', 'B-cells (Spleen)': '-0.011', 'NK-cells (Spleen)': '-0.033', 'Amygdala excitatory': '7.1', 'Cerebellar inhibitory': '4.8', 'Cge interneuron': '3.7', 'Deep-layer corticothalamic and 6b': '6.9', 'Deep-layer intratelencephalic': '6.4', 'Deep-layer near-projecting': '6.9', 'Eccentric medium spiny neuron': '5.9', 'Hippocampal ca1-3': '6.5', 'Hippocampal ca4': '7.5', 'Hippocampal dentate gyrus': '3.9', 'Lamp5-lhx6 and chandelier': '2.6', 'Lower rhombic lip': '6.1', 'Mammillary body': '7.0', 'Medium spiny neuron': '6.0', 'Mge interneuron': '5.3', 'Midbrain-derived inhibitory': '6.6', 'Miscellaneous': '5.8', 'Splatter': '4.9', 'Thalamic excitatory': '6.7', 'Upper rhombic lip': '1.7', 'Upper-layer intratelencephalic': '6.0', 'Astrocyte': '6.6', 'Bergmann glia': '5.1', 'Central nervous system macrophage': '4.0', 'Choroid plexus epithelial cell': '2.1', 'Committed oligodendrocyte precursor': '2.3', 'Ependymal cell': '5.9', 'Oligodendrocyte': '4.3', 'Oligodendrocyte precursor cell': '2.2', 'Endothelial cell': '6.2', 'Pericyte': '1.5', 'Vascular associated smooth muscle cell': '2.3', 'Fibroblast': '2.0', 'Leukocyte': '2.7', 'Basophil': '0.9', 'Eosinophil': '0.2', 'Neutrophil': '1.4', 'Classical monocyte': '0.9', 'Non-classical monocyte': '1.1', 'Intermediate monocyte': '0.7', 'T-reg': '2.2', 'GdT-cell': '0.1', 'MAIT T-cell': '0.5', 'Memory CD4 T-cell': '0.1', 'Naive CD4 T-cell': '2.5', 'Memory CD8 T-cell': '0.2', 'Naive CD8 T-cell': '1.9', 'Memory B-cell': '0.3', 'Naive B-cell': '2.1', 'Plasmacytoid DC': '3.0', 'Myeloid DC': '1.1', 'NK-cell': '2.1', 'Total PBMC': '1.4', 'Vd2 gdTCR': '0.5', 'Memory CD4 T-cell Th1\\/Th17': '2.2', 'Memory CD4 T-cell Th17': '2.2', 'Memory CD4 T-cell Th2': '2.8', 'Non-Vd2 gdTCR': '0.9', 'Memory CD4 T-cell Th1': '2.5', 'Memory CD4 T-cell TFH': '2.0', 'Terminal effector memory CD4 T-cell': '1.5', 'Central memory CD8 T-cell': '0.9', 'Effector memory CD8 T-cell': '2.1', 'Terminal effector memory CD8 T-cell': '0.6', 'Non-switched memory B-cell': '1.0', 'Plasmablast': '8.1', 'Switched memory B-cell': '0.9', 'Exhausted memory B-cell': '4.5', 'Progenitor cell': '2.2', 'Memory T-reg': '3.2', 'Naive CD4 T-cell activated': '5.8', 'Naive CD8 T-cell activated': '3.8', 'Naive T-reg': '2.0'} | 4YYP, 5LHW, 5LHZ, 8OYK, 8OYL | {'Adipose Tissue': 0.9901666943521594, 'Adrenal Gland': 0.7493770930232558, 'Bladder': 0.9425142857142856, 'Blood': 4.488175009687837, 'Blood Vessel': 0.5636820149812735, 'Brain': 0.7385426154428463, 'Breast': 1.2491721132897604, 'Cervix Uteri': 1.0014105263157895, 'Colon': 1.9123311553273428, 'Esophagus': 1.745949750865052, 'Fallopian Tube': 0.8377, 'Heart': 0.2820289326364692, 'Kidney': 0.7304966292134831, 'Liver': 0.5065336283185841, 'Lung': 1.49800830449827, 'Muscle': 0.2364307222914072, 'Nerve': 0.9094174474959612, 'Ovary': 1.0490244444444443, 'Pancreas': 0.4592714634146341, 'Pituitary': 0.7898918727915194, 'Prostate': 1.599735020408163, 'Salivary Gland': 2.6179135802469133, 'Skin': 4.266187396351576, 'Small Intestine': 3.0804090909090913, 'Spleen': 2.566144813278008, 'Stomach': 1.2696304456824512, 'Testis': 9.933952908587258, 'Thyroid': 1.0626485451761103, 'Uterus': 0.8795042253521127, 'Vagina': 2.0071641025641025} | [39.93, 46.46, 52.9, 44.21, 41.4, 39.93, 35.91, 38.61, 36.44, 36.25, 34.86, 32.82, 32.01, 32.75, 31.69, 35.64, 36.35, 34.66, 33.32, 32.71, 35.01, 30.17, 37.05, 36.53, 48.19, 58.22, 64.94, 73.22, 78.33, 82.63, 85.79, 89.39, 87.89, 85.58, 83.93, 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0.99, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 0.98, 0.99, 0.96, 0.99, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 0.85, 1.0, 0.89, 0.91, 0.85, 0.78, 0.99, 0.89, 0.79, 0.44, 0.57, 0.75, 0.71, 0.48, 0.84, 0.75, 0.75, 0.87, 0.92, 0.93, 0.95] | null | Component of an E-cadherin/ catenin adhesion complex composed of at least E-cadherin/CDH1, beta-catenin/CTNNB1 or gamma-catenin/JUP, and potentially alpha-catenin/CTNNA1. Forms a ternary complex composed of ADAM10, CADH1 and EPHA4, | null | null | KLRG1, SPEF1, DLGAP5, AJAP1, RAPGEF2, RAB8B, PIP5K1C, PKP2, TRPV4, CTNNB1, CAV1, DDR1, TBC1D2, CTNNA1, JUP, CTNND1, PSEN1, LIMA1, CDH1, JUP, ADAM10, CADH1 , EPHA4, | null | null | null | null | Homodimer | null | 79.91949 | 0.474025 | 53.109953 | 0.722347 | 288 |
P12830 | Q15468-2 | null | degron_data | CDH1 | MGPWSRSLSALLLLLQVSSWLCQEPEPCHPGFDAESYTFTVPRRHLERGRVLGRVNFEDCTGRQRTAYFSLDTRFKVGTDGVITVKRPLRFHNPQIHFLVYAWDSTYRKFSTKVTLNTVGHHHRPPPHQASVSGIQAELLTFPNSSPGLRRQKRDWVIPPISCPENEKGPFPKNLVQIKSNKDKEGKVFYSITGQGADTPPVGVFIIERETGWLKVTEPLDRERIATYTLFSHAVSSNGNAVEDPMEILITVTDQNDNKPEFTQEVFKGSVMEGALPGTSVMEVTATDADDDVNTYNAAIAYTILSQDPELPDKNMFTINRNTGVISVVTTGLDRESFPTYTLVVQAADLQGEGLSTTATAVITVTDTNDNPPIFNPTTYKGQVPENEANVVITTLKVTDADAPNTPAWEAVYTILNDDGGQFVVTTNPVNNDGILKTAKGLDFEAKQQYILHVAVTNVVPFEVSLTTSTATVTVDVLDVNEAPIFVPPEKRVEVSEDFGVGQEITSYTAQEPDTFMEQKITYRIWRDTANWLEINPDTGAISTRAELDREDFEHVKNSTYTALIIATDNGSPVATGTGTLLLILSDVNDNAPIPEPRTIFFCERNPKPQVINIIDADLPPNTSPFTAELTHGASANWTIQYNDPTQESIILKPKMALEVGDYKINLKLMDNQNKDQVTTLEVSVCDCEGAAGVCRKAQPVEAGLQIPAILGILGGILALLILILLLLLFLRRRAVVKEPLLPPEDDTRDNVYYYDEEGGGEEDQDFDLSQLHRGLDARPEVTRNDVAPTLMSVPRYLPRPANPDEIGNFIDENLKAADTDPTAPPYDSLLVFDYEGSGSEAASLSSLNSSESDKDQDYDYLNEWGNRFKKLADMYGGGEDD | Homo sapiens | Cell junction, adherens junction, Cell membrane, Endosome, Golgi apparatus, trans-Golgi network, Cytoplasm, Cell junction, desmosome | Tissue enhanced (parathyroid) | {'Ciliated cells': '119.1', 'Basal respiratory cells': '71.1', 'Club cells': '97.3', 'Ionocytes': '81.0', 'Mucus glandular cells': '155.0', 'Serous glandular cells': '67.8', 'Gastric mucus-secreting cells': '133.2', 'Proximal enterocytes': '140.9', 'Paneth cells': '125.1', 'Distal enterocytes': '307.5', 'Intestinal goblet cells': '173.5', 'Exocrine glandular cells': '-0.605', 'Basal prostatic cells': '68.3', 'Prostatic glandular cells': '186.7', 'Breast glandular cells': '0.773', 'Breast myoepithelial cells': '0.700', 'Glandular and luminal cells': '313.0', 'Secretory cells': '82.3', 'Basal keratinocytes': '102.5', 'Suprabasal keratinocytes': '162.6', 'Basal squamous epithelial cells': '51.0', 'Squamous epithelial cells': '106.9', 'Alveolar cells type 1': '0.437', 'Alveolar cells type 2': '0.706', 'Salivary duct cells': '95.9', 'Ductal cells': '0.541', 'Hepatocytes': '0.600', 'Cholangiocytes': '129.7', 'Proximal tubular cells': '0.042', 'Distal tubular cells': '0.0', 'Collecting duct cells': '143.9', 'Mesothelial cells': '0.799', 'Sertoli cells': '0.252', 'Granulosa cells': '12.9', 'Enteroendocrine cells': '92.4', 'Pancreatic endocrine cells': '78.1', 'Leydig cells': '0.264', 'Excitatory neurons': '0.7', 'Inhibitory neurons': '1.3', 'Cone photoreceptor cells': '0.0', 'Rod photoreceptor cells': '0.0', 'Bipolar cells': '0.2', 'Horizontal cells': '0.6', 'Astrocytes': '0.6', 'Oligodendrocyte precursor cells': '0.5', 'Oligodendrocytes': '29.9', 'Microglial cells': '0.9', 'Muller glia cells': '0.1', 'Schwann cells': '0.131', 'Spermatogonia': '0.392', 'Spermatocytes': '0.193', 'Early spermatids': '-0.217', 'Late spermatids': '-0.290', 'Oocytes': '16.9', 'Cytotrophoblasts': '119.2', 'Syncytiotrophoblasts': '45.0', 'Extravillous trophoblasts': '24.9', 'Endothelial cells': '6.1', 'Lymphatic endothelial cells': '0.4', 'Cardiomyocytes': '0.135', 'Skeletal myocytes': '0.107', 'Smooth muscle cells': '5.8', 'Adipocytes': '2.1', 'Melanocytes': '0.335', 'Fibroblasts': '6.5', 'Peritubular cells': '0.210', 'Endometrial stromal cells': '27.7', 'Ovarian stromal cells': '0.7', 'Undifferentiated cells': '101.6', 'T-cells': '2.9', 'B-cells': '4.4', 'Plasma cells': '6.1', 'Nk-cells': '0.0', 'Granulocytes': '8.4', 'Monocytes': '0.0', 'Macrophages': '6.0', 'Hofbauer cells': '4.3', 'Kupffer cells': '1.0', 'Dendritic cells': '5.9', 'Langerhans cells': '0.304', 'Erythroid cells': '0.036', 'Adipocytes (Subcutaneous)': '-0.081', 'Adipocytes (Visceral)': '-0.209', 'Breast glandular cells (progenitors)': '0.538', 'Adipocytes (Breast)': '-0.689', 'Colon enterocytes': '0.790', 'Colon enteroendocrine cells': '0.112', 'Enteric glia cells': '-0.048', 'Mitotic cells (Colon)': '0.299', 'Mitotic cells (Heart)': '0.120', 'Podocytes': '-0.118', 'Ascending Loop of Henle cells': '0.475', 'Intercalated cells': '0.212', 'Cholangiocyte': '0.090', 'NK-cells (Liver)': '-0.005', 'Respiratory ciliated cells': '-0.012', 'Mitotic cells (Lung)': '0.071', 'NK-cells (Lung)': '-0.266', 'B-cells (Lung)': '-0.296', 'Alpha cells': '0.270', 'Beta cells': '0.152', 'Prostate glandular cells': '0.764', 'Prostate basal glandular cells': '0.540', 'Urothelial cells': '0.205', 'Keratinocyte (other)': '0.510', 'Keratinocyte (granular)': '0.055', 'Hair cortex cells': '0.080', 'Inner root sheath cells': '0.131', 'Outer root sheath cells': '0.175', 'Sebaceous gland cells': '0.156', 'Eccrine sweat gland cells': '-0.207', 'Adipocytes (Skin)': '-0.244', 'Mitotic cells (Skin)': '0.442', 'Parietal cells': '0.654', 'Chief cells': '0.649', 'Gastric mucous cells': '0.781', 'Gastric enteroendocrine cells': '0.590', 'Mitotic cells (Stomach)': '0.445', 'Parafollicular cells': '0.173', 'Thyroid glandular cells': '0.865', 'Mitotic cells (Thyroid)': '-0.081', 'Adrenal cortex cells': '0.051', 'Adrenal medulla cells': '0.087', 'Mitotic cells (Adrenal gland)': '0.072', 'Minor salivary glandular cells': '0.371', 'Minor salivary gland ductal cells': '-0.142', 'Minor salivary gland basal cells': '0.582', 'Mitotic cells (Minor salivary gland)': '0.567', 'Adipocytes (Minor salivary gland)': '0.050', 'Somatotropes': '0.121', 'Lactotropes': '0.322', 'Gonadotropes': '0.330', 'Corticotropes': '0.180', 'Thyrotropes': '0.496', 'Undifferentiated cells (Pituitary gland)': '-0.108', 'Mitotic cells (Spleen)': '-0.228', 'Platelets': '-0.050', 'Erythrocytes': '-0.158', 'Hematopoietic stem cells': '-0.211', 'B-cells (Spleen)': '0.266', 'NK-cells (Spleen)': '0.309', 'Amygdala excitatory': '1.0', 'Cerebellar inhibitory': '0.9', 'Cge interneuron': '0.7', 'Deep-layer corticothalamic and 6b': '1.5', 'Deep-layer intratelencephalic': '0.7', 'Deep-layer near-projecting': '0.7', 'Eccentric medium spiny neuron': '0.6', 'Hippocampal ca1-3': '1.9', 'Hippocampal ca4': '1.2', 'Hippocampal dentate gyrus': '1.1', 'Lamp5-lhx6 and chandelier': '0.5', 'Lower rhombic lip': '0.8', 'Mammillary body': '0.6', 'Medium spiny neuron': '0.7', 'Mge interneuron': '1.7', 'Midbrain-derived inhibitory': '0.7', 'Miscellaneous': '0.9', 'Splatter': '3.8', 'Thalamic excitatory': '0.5', 'Upper rhombic lip': '0.8', 'Upper-layer intratelencephalic': '0.6', 'Astrocyte': '4.4', 'Bergmann glia': '0.2', 'Central nervous system macrophage': '0.6', 'Choroid plexus epithelial cell': '52.1', 'Committed oligodendrocyte precursor': '41.5', 'Ependymal cell': '4.8', 'Oligodendrocyte': '53.1', 'Oligodendrocyte precursor cell': '2.4', 'Endothelial cell': '0.7', 'Pericyte': '0.3', 'Vascular associated smooth muscle cell': '0.0', 'Fibroblast': '17.4', 'Leukocyte': '1.1', 'Basophil': '0.0', 'Eosinophil': '0.0', 'Neutrophil': '0.0', 'Classical monocyte': '0.0', 'Non-classical monocyte': '0.0', 'Intermediate monocyte': '0.0', 'T-reg': '2.3', 'GdT-cell': '0.0', 'MAIT T-cell': '0.0', 'Memory CD4 T-cell': '0.0', 'Naive CD4 T-cell': '0.1', 'Memory CD8 T-cell': '0.2', 'Naive CD8 T-cell': '0.3', 'Memory B-cell': '0.0', 'Naive B-cell': '0.1', 'Plasmacytoid DC': '46.6', 'Myeloid DC': '8.5', 'NK-cell': '0.1', 'Total PBMC': '0.7', 'Vd2 gdTCR': '0.0', 'Memory CD4 T-cell Th1\\/Th17': '0.1', 'Memory CD4 T-cell Th17': '0.2', 'Memory CD4 T-cell Th2': '2.9', 'Non-Vd2 gdTCR': '0.1', 'Memory CD4 T-cell Th1': '0.3', 'Memory CD4 T-cell TFH': '0.5', 'Terminal effector memory CD4 T-cell': '0.0', 'Central memory CD8 T-cell': '4.8', 'Effector memory CD8 T-cell': '0.0', 'Terminal effector memory CD8 T-cell': '0.6', 'Non-switched memory B-cell': '0.0', 'Plasmablast': '3.3', 'Switched memory B-cell': '0.0', 'Exhausted memory B-cell': '0.7', 'Progenitor cell': '2.3', 'Memory T-reg': '1.3', 'Naive CD4 T-cell activated': '0.3', 'Naive CD8 T-cell activated': '0.6', 'Naive T-reg': '0.1'} | 1O6S, 2O72, 2OMT, 2OMU, 2OMV, 2OMX, 2OMY, 2OMZ, 3FF7, 3FF8, 3L6X, 3L6Y, 4ZT1, 4ZTE, 6CXY, 6OLE, 6OLF, 6OLG, 6VEL, 7STZ, 8H62 | {'Adipose Tissue': 1.2125261088039867, 'Adrenal Gland': 0.1914223992248062, 'Bladder': 39.2033519047619, 'Blood': 1.340954264800861, 'Blood Vessel': 0.3121561692883895, 'Brain': 0.8550442199091597, 'Breast': 38.54918344226579, 'Cervix Uteri': 23.539115789473684, 'Colon': 43.41292142490372, 'Esophagus': 53.97513367404844, 'Fallopian Tube': 14.900277777777776, 'Heart': 0.119140469221835, 'Kidney': 25.040449438202245, 'Liver': 26.60802654867257, 'Lung': 35.447986366782004, 'Muscle': 0.1378936151930261, 'Nerve': 17.518468982229404, 'Ovary': 3.6515122222222223, 'Pancreas': 56.89676829268293, 'Pituitary': 24.68741660777385, 'Prostate': 61.279967346938776, 'Salivary Gland': 92.01685185185184, 'Skin': 79.77571720232172, 'Small Intestine': 71.7519320855615, 'Spleen': 10.061029045643156, 'Stomach': 58.07813805013927, 'Testis': 0.8144204986149585, 'Thyroid': 135.176797856049, 'Uterus': 1.442593943661972, 'Vagina': 86.52345512820513} | STIL | MEPIYPFARPQMNTRFPSSRMVPFHFPPSKCALWNPTPTGDFIYLHLSYYRNPKLVVTEKTIRLAYRHAKQNKKNSSCFLLGSLTADEDEEGVTLTVDRFDPGREVPECLEITPTASLPGDFLIPCKVHTQELCSREMIVHSVDDFSSALKALQCHICSKDSLDCGKLLSLRVHITSRESLDSVEFDLHWAAVTLANNFKCTPVKPIPIIPTALARNLSSNLNISQVQGTYKYGYLTMDETRKLLLLLESDPKVYSLPLVGIWLSGITHIYSPQVWACCLRYIFNSSVQERVFSESGNFIIVLYSMTHKEPEFYECFPCDGKIPDFRFQLLTSKETLHLFKNVEPPDKNPIRCELSAESQNAETEFFSKASKNFSIKRSSQKLSSGKMPIHDHDSGVEDEDFSPRPIPSPHPVSQKISKIQPSVPELSLVLDGNFIESNPLPTPLEMVNNENPPLINHLEHLKPLQPQLYDEKHSPEVEAGEPSLRGIPNQLNQDKPALLRHCKVRQPPAYKKGNPHTRNSIKPSSHNGPSHDIFEKLQTVSAGNVQNEEYPIRPSTLNSRQSSLAPQSQPHDFVFSPHNSGRPMELQIPTPPLPSYCSTNVCRCCQHHSHIQYSPLNSWQGANTVGSIQDVQSEALQKHSLFHPSGCPALYCNAFCSSSSPIALRPQGDMGSCSPHSNIEPSPVARPPSHMDLCNPQPCTVCMHTPKTESDNGMMGLSPDAYRFLTEQDRQLRLLQAQIQRLLEAQSLMPCSPKTTAVEDTVQAGRQMELVSVEAQSSPGLHMRKGVSIAVSTGASLFWNAAGEDQEPDSQMKQDDTKISSEDMNFSVDINNEVTSLPGSASSLKAVDIPSFEESNIAVEEEFNQPLSVSNSSSLVVRKEPDVPVFFPSGQLAESVSMCLQTGPTGGASNNSETSEEPKIEHVMQPLLHQPSDNQKIYQDLLGQVNHLLNSSSKETEQPSTKAVIISHECTRTQNVYHTKKKTHHSRLVDKDCVLNATLKQLRSLGVKIDSPTKVKKNAHNVDHASVLACISPEAVISGLNCMSFANVGMSGLSPNGVDLSMEANAIALKYLNENQLSQLSVTRSNQNNCDPFSLLHINTDRSTVGLSLISPNNMSFATKKYMKRYGLLQSSDNSEDEEEPPDNADSKSEYLLNQNLRSIPEQLGGQKEPSKNDHEIINCSNCESVGTNADTPVLRNITNEVLQTKAKQQLTEKPAFLVKNLKPSPAVNLRTGKAEFTQHPEKENEGDITIFPESLQPSETLKQMNSMNSVGTFLDVKRLRQLPKLF | Homo sapiens | null | Not found | {} | null | {'Adipose Tissue': 0.9901666943521594, 'Adrenal Gland': 0.7493770930232558, 'Bladder': 0.9425142857142856, 'Blood': 4.488175009687837, 'Blood Vessel': 0.5636820149812735, 'Brain': 0.7385426154428463, 'Breast': 1.2491721132897604, 'Cervix Uteri': 1.0014105263157895, 'Colon': 1.9123311553273428, 'Esophagus': 1.745949750865052, 'Fallopian Tube': 0.8377, 'Heart': 0.2820289326364692, 'Kidney': 0.7304966292134831, 'Liver': 0.5065336283185841, 'Lung': 1.49800830449827, 'Muscle': 0.2364307222914072, 'Nerve': 0.9094174474959612, 'Ovary': 1.0490244444444443, 'Pancreas': 0.4592714634146341, 'Pituitary': 0.7898918727915194, 'Prostate': 1.599735020408163, 'Salivary Gland': 2.6179135802469133, 'Skin': 4.266187396351576, 'Small Intestine': 3.0804090909090913, 'Spleen': 2.566144813278008, 'Stomach': 1.2696304456824512, 'Testis': 9.933952908587258, 'Thyroid': 1.0626485451761103, 'Uterus': 0.8795042253521127, 'Vagina': 2.0071641025641025} | [39.93, 46.46, 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0.53, 0.67, 0.5, 0.56, 0.14, 0.18, 0.47, 0.01, 0.47, 0.15, 0.61, 0.28, 0.2, 0.02, 0.76, 0.55, 0.31, 0.94, 0.22, 0.57, 0.17, 0.4, 0.07, 0.5, 0.31, 0.7, 0.2, 0.14, 0.3, 0.23, 0.58, 0.07, 0.06, 0.55, 0.15, 0.46, 0.43, 0.64, 0.53, 0.0, 0.18, 0.01, 0.23, 0.02, 0.63, 0.33, 0.79, 0.06, 0.38, 0.07, 0.14, 0.23, 0.68, 0.89, 0.29, 0.06, 0.72, 0.92, 0.24, 0.25, 0.0, 0.46, 0.02, 0.21, 0.01, 0.06, 0.0, 0.05, 0.07, 0.61, 0.17, 0.89, 0.72, 0.66, 0.14, 0.52, 0.07, 0.58, 0.01, 0.26, 0.0, 0.13, 0.0, 0.29, 0.04, 0.46, 0.27, 0.28, 0.23, 0.56, 0.32, 0.25, 0.0, 0.33, 0.05, 0.55, 0.5, 0.58, 0.53, 0.04, 0.27, 0.02, 0.04, 0.37, 0.67, 0.74, 0.35, 0.62, 0.54, 0.26, 0.46, 0.0, 0.47, 0.09, 0.45, 0.15, 0.39, 0.05, 0.44, 0.85, 0.56, 0.11, 0.11, 0.35, 0.42, 0.03, 0.32, 0.12, 0.49, 0.19, 0.25, 0.8, 0.6, 0.09, 0.49, 0.57, 0.36, 0.04, 0.35, 0.28, 0.52, 0.39, 0.5, 0.28, 0.93, 0.47, 0.3, 0.47, 0.08, 0.02, 0.18, 0.01, 0.34, 0.23, 0.55, 0.57, 0.91, 0.1, 0.78, 0.52, 0.34, 0.61, 0.24, 0.75, 0.0, 0.2, 0.02, 0.24, 0.0, 0.18, 0.04, 0.44, 0.59, 0.71, 0.29, 0.52, 0.37, 0.5, 0.11, 0.6, 0.02, 0.48, 0.01, 0.16, 0.04, 0.35, 0.66, 0.47, 0.74, 0.14, 0.62, 0.16, 0.77, 0.79, 0.27, 0.93, 0.69, 0.88, 0.88, 0.85, 0.87, 0.91, 0.92, 0.82, 0.63, 0.75, 0.7, 0.7, 0.38, 0.43, 0.64, 0.55, 0.54, 0.59, 0.45, 0.47, 0.5, 0.58, 0.52, 0.61, 0.57, 0.52, 0.68, 0.44, 0.6, 0.61, 0.58, 0.55, 0.5, 0.61, 0.61, 0.86, 0.86, 0.75, 0.91, 0.96, 0.93, 1.0, 0.87, 0.97, 0.91, 0.95, 0.86, 0.98, 0.93, 0.88, 0.59, 0.87, 0.7, 0.67, 0.85, 0.89, 0.88, 0.91, 0.93, 0.88, 0.99, 0.92, 1.0, 0.79, 0.9, 1.0, 0.94, 1.0, 0.97, 0.96, 0.9, 0.63, 0.68, 0.48, 0.54, 0.8, 0.7, 0.7, 0.95, 0.87, 0.77, 0.84, 0.79, 0.89, 0.95, 0.8, 0.77, 0.51, 0.87, 0.7, 0.52, 0.84, 0.91, 0.51, 0.96, 0.79, 0.92, 0.84, 0.21, 0.89, 0.53, 0.52, 0.89, 0.86, 0.26, 0.91, 0.45, 0.68, 0.84, 0.48, 0.44, 0.51, 0.62, 0.28, 0.59, 0.63, 0.57, 0.15, 0.55, 0.66, 0.1, 0.38, 0.74, 0.65, 0.17, 0.43, 0.66, 0.41, 0.8, 0.75, 0.9, 0.93, 0.52, 0.76, 0.89, 0.87, 0.76, 0.92, 0.91, 0.75, 0.61, 0.96, 0.89, 0.73, 0.97, 0.68, 0.87, 0.55, 0.85, 0.77, 0.69, 0.76, 0.98, 0.83, 0.68, 0.82, 0.74, 0.65, 0.96, 0.93, 0.54, 0.64, 0.28, 0.54, 0.52, 0.16, 0.51, 0.88, 0.6, 0.4, 0.88, 0.95, 0.33, 0.56, 0.73, 0.39, 0.06, 0.61, 0.75, 0.47, 0.19, 0.87, 0.7, 0.97, 0.94, 0.97] | null | null | null | Component of an E-cadherin/ catenin adhesion complex composed of at least E-cadherin/CDH1, beta-catenin/CTNNB1 or gamma-catenin/JUP, and potentially alpha-catenin/CTNNA1. Forms a ternary complex composed of ADAM10, CADH1 and EPHA4, | null | null | KLRG1, SPEF1, DLGAP5, AJAP1, RAPGEF2, RAB8B, PIP5K1C, PKP2, TRPV4, CTNNB1, CAV1, DDR1, TBC1D2, CTNNA1, JUP, CTNND1, PSEN1, LIMA1, CDH1, JUP, ADAM10, CADH1 , EPHA4, | null | null | null | null | Homodimer | null | 79.91949 | 0.474025 | null | null | 288 |
P12830 | Q15784 | null | degron_data | CDH1 | MGPWSRSLSALLLLLQVSSWLCQEPEPCHPGFDAESYTFTVPRRHLERGRVLGRVNFEDCTGRQRTAYFSLDTRFKVGTDGVITVKRPLRFHNPQIHFLVYAWDSTYRKFSTKVTLNTVGHHHRPPPHQASVSGIQAELLTFPNSSPGLRRQKRDWVIPPISCPENEKGPFPKNLVQIKSNKDKEGKVFYSITGQGADTPPVGVFIIERETGWLKVTEPLDRERIATYTLFSHAVSSNGNAVEDPMEILITVTDQNDNKPEFTQEVFKGSVMEGALPGTSVMEVTATDADDDVNTYNAAIAYTILSQDPELPDKNMFTINRNTGVISVVTTGLDRESFPTYTLVVQAADLQGEGLSTTATAVITVTDTNDNPPIFNPTTYKGQVPENEANVVITTLKVTDADAPNTPAWEAVYTILNDDGGQFVVTTNPVNNDGILKTAKGLDFEAKQQYILHVAVTNVVPFEVSLTTSTATVTVDVLDVNEAPIFVPPEKRVEVSEDFGVGQEITSYTAQEPDTFMEQKITYRIWRDTANWLEINPDTGAISTRAELDREDFEHVKNSTYTALIIATDNGSPVATGTGTLLLILSDVNDNAPIPEPRTIFFCERNPKPQVINIIDADLPPNTSPFTAELTHGASANWTIQYNDPTQESIILKPKMALEVGDYKINLKLMDNQNKDQVTTLEVSVCDCEGAAGVCRKAQPVEAGLQIPAILGILGGILALLILILLLLLFLRRRAVVKEPLLPPEDDTRDNVYYYDEEGGGEEDQDFDLSQLHRGLDARPEVTRNDVAPTLMSVPRYLPRPANPDEIGNFIDENLKAADTDPTAPPYDSLLVFDYEGSGSEAASLSSLNSSESDKDQDYDYLNEWGNRFKKLADMYGGGEDD | Homo sapiens | Cell junction, adherens junction, Cell membrane, Endosome, Golgi apparatus, trans-Golgi network, Cytoplasm, Cell junction, desmosome | Tissue enhanced (parathyroid) | {'Ciliated cells': '119.1', 'Basal respiratory cells': '71.1', 'Club cells': '97.3', 'Ionocytes': '81.0', 'Mucus glandular cells': '155.0', 'Serous glandular cells': '67.8', 'Gastric mucus-secreting cells': '133.2', 'Proximal enterocytes': '140.9', 'Paneth cells': '125.1', 'Distal enterocytes': '307.5', 'Intestinal goblet cells': '173.5', 'Exocrine glandular cells': '-0.605', 'Basal prostatic cells': '68.3', 'Prostatic glandular cells': '186.7', 'Breast glandular cells': '0.773', 'Breast myoepithelial cells': '0.700', 'Glandular and luminal cells': '313.0', 'Secretory cells': '82.3', 'Basal keratinocytes': '102.5', 'Suprabasal keratinocytes': '162.6', 'Basal squamous epithelial cells': '51.0', 'Squamous epithelial cells': '106.9', 'Alveolar cells type 1': '0.437', 'Alveolar cells type 2': '0.706', 'Salivary duct cells': '95.9', 'Ductal cells': '0.541', 'Hepatocytes': '0.600', 'Cholangiocytes': '129.7', 'Proximal tubular cells': '0.042', 'Distal tubular cells': '0.0', 'Collecting duct cells': '143.9', 'Mesothelial cells': '0.799', 'Sertoli cells': '0.252', 'Granulosa cells': '12.9', 'Enteroendocrine cells': '92.4', 'Pancreatic endocrine cells': '78.1', 'Leydig cells': '0.264', 'Excitatory neurons': '0.7', 'Inhibitory neurons': '1.3', 'Cone photoreceptor cells': '0.0', 'Rod photoreceptor cells': '0.0', 'Bipolar cells': '0.2', 'Horizontal cells': '0.6', 'Astrocytes': '0.6', 'Oligodendrocyte precursor cells': '0.5', 'Oligodendrocytes': '29.9', 'Microglial cells': '0.9', 'Muller glia cells': '0.1', 'Schwann cells': '0.131', 'Spermatogonia': '0.392', 'Spermatocytes': '0.193', 'Early spermatids': '-0.217', 'Late spermatids': '-0.290', 'Oocytes': '16.9', 'Cytotrophoblasts': '119.2', 'Syncytiotrophoblasts': '45.0', 'Extravillous trophoblasts': '24.9', 'Endothelial cells': '6.1', 'Lymphatic endothelial cells': '0.4', 'Cardiomyocytes': '0.135', 'Skeletal myocytes': '0.107', 'Smooth muscle cells': '5.8', 'Adipocytes': '2.1', 'Melanocytes': '0.335', 'Fibroblasts': '6.5', 'Peritubular cells': '0.210', 'Endometrial stromal cells': '27.7', 'Ovarian stromal cells': '0.7', 'Undifferentiated cells': '101.6', 'T-cells': '2.9', 'B-cells': '4.4', 'Plasma cells': '6.1', 'Nk-cells': '0.0', 'Granulocytes': '8.4', 'Monocytes': '0.0', 'Macrophages': '6.0', 'Hofbauer cells': '4.3', 'Kupffer cells': '1.0', 'Dendritic cells': '5.9', 'Langerhans cells': '0.304', 'Erythroid cells': '0.036', 'Adipocytes (Subcutaneous)': '-0.081', 'Adipocytes (Visceral)': '-0.209', 'Breast glandular cells (progenitors)': '0.538', 'Adipocytes (Breast)': '-0.689', 'Colon enterocytes': '0.790', 'Colon enteroendocrine cells': '0.112', 'Enteric glia cells': '-0.048', 'Mitotic cells (Colon)': '0.299', 'Mitotic cells (Heart)': '0.120', 'Podocytes': '-0.118', 'Ascending Loop of Henle cells': '0.475', 'Intercalated cells': '0.212', 'Cholangiocyte': '0.090', 'NK-cells (Liver)': '-0.005', 'Respiratory ciliated cells': '-0.012', 'Mitotic cells (Lung)': '0.071', 'NK-cells (Lung)': '-0.266', 'B-cells (Lung)': '-0.296', 'Alpha cells': '0.270', 'Beta cells': '0.152', 'Prostate glandular cells': '0.764', 'Prostate basal glandular cells': '0.540', 'Urothelial cells': '0.205', 'Keratinocyte (other)': '0.510', 'Keratinocyte (granular)': '0.055', 'Hair cortex cells': '0.080', 'Inner root sheath cells': '0.131', 'Outer root sheath cells': '0.175', 'Sebaceous gland cells': '0.156', 'Eccrine sweat gland cells': '-0.207', 'Adipocytes (Skin)': '-0.244', 'Mitotic cells (Skin)': '0.442', 'Parietal cells': '0.654', 'Chief cells': '0.649', 'Gastric mucous cells': '0.781', 'Gastric enteroendocrine cells': '0.590', 'Mitotic cells (Stomach)': '0.445', 'Parafollicular cells': '0.173', 'Thyroid glandular cells': '0.865', 'Mitotic cells (Thyroid)': '-0.081', 'Adrenal cortex cells': '0.051', 'Adrenal medulla cells': '0.087', 'Mitotic cells (Adrenal gland)': '0.072', 'Minor salivary glandular cells': '0.371', 'Minor salivary gland ductal cells': '-0.142', 'Minor salivary gland basal cells': '0.582', 'Mitotic cells (Minor salivary gland)': '0.567', 'Adipocytes (Minor salivary gland)': '0.050', 'Somatotropes': '0.121', 'Lactotropes': '0.322', 'Gonadotropes': '0.330', 'Corticotropes': '0.180', 'Thyrotropes': '0.496', 'Undifferentiated cells (Pituitary gland)': '-0.108', 'Mitotic cells (Spleen)': '-0.228', 'Platelets': '-0.050', 'Erythrocytes': '-0.158', 'Hematopoietic stem cells': '-0.211', 'B-cells (Spleen)': '0.266', 'NK-cells (Spleen)': '0.309', 'Amygdala excitatory': '1.0', 'Cerebellar inhibitory': '0.9', 'Cge interneuron': '0.7', 'Deep-layer corticothalamic and 6b': '1.5', 'Deep-layer intratelencephalic': '0.7', 'Deep-layer near-projecting': '0.7', 'Eccentric medium spiny neuron': '0.6', 'Hippocampal ca1-3': '1.9', 'Hippocampal ca4': '1.2', 'Hippocampal dentate gyrus': '1.1', 'Lamp5-lhx6 and chandelier': '0.5', 'Lower rhombic lip': '0.8', 'Mammillary body': '0.6', 'Medium spiny neuron': '0.7', 'Mge interneuron': '1.7', 'Midbrain-derived inhibitory': '0.7', 'Miscellaneous': '0.9', 'Splatter': '3.8', 'Thalamic excitatory': '0.5', 'Upper rhombic lip': '0.8', 'Upper-layer intratelencephalic': '0.6', 'Astrocyte': '4.4', 'Bergmann glia': '0.2', 'Central nervous system macrophage': '0.6', 'Choroid plexus epithelial cell': '52.1', 'Committed oligodendrocyte precursor': '41.5', 'Ependymal cell': '4.8', 'Oligodendrocyte': '53.1', 'Oligodendrocyte precursor cell': '2.4', 'Endothelial cell': '0.7', 'Pericyte': '0.3', 'Vascular associated smooth muscle cell': '0.0', 'Fibroblast': '17.4', 'Leukocyte': '1.1', 'Basophil': '0.0', 'Eosinophil': '0.0', 'Neutrophil': '0.0', 'Classical monocyte': '0.0', 'Non-classical monocyte': '0.0', 'Intermediate monocyte': '0.0', 'T-reg': '2.3', 'GdT-cell': '0.0', 'MAIT T-cell': '0.0', 'Memory CD4 T-cell': '0.0', 'Naive CD4 T-cell': '0.1', 'Memory CD8 T-cell': '0.2', 'Naive CD8 T-cell': '0.3', 'Memory B-cell': '0.0', 'Naive B-cell': '0.1', 'Plasmacytoid DC': '46.6', 'Myeloid DC': '8.5', 'NK-cell': '0.1', 'Total PBMC': '0.7', 'Vd2 gdTCR': '0.0', 'Memory CD4 T-cell Th1\\/Th17': '0.1', 'Memory CD4 T-cell Th17': '0.2', 'Memory CD4 T-cell Th2': '2.9', 'Non-Vd2 gdTCR': '0.1', 'Memory CD4 T-cell Th1': '0.3', 'Memory CD4 T-cell TFH': '0.5', 'Terminal effector memory CD4 T-cell': '0.0', 'Central memory CD8 T-cell': '4.8', 'Effector memory CD8 T-cell': '0.0', 'Terminal effector memory CD8 T-cell': '0.6', 'Non-switched memory B-cell': '0.0', 'Plasmablast': '3.3', 'Switched memory B-cell': '0.0', 'Exhausted memory B-cell': '0.7', 'Progenitor cell': '2.3', 'Memory T-reg': '1.3', 'Naive CD4 T-cell activated': '0.3', 'Naive CD8 T-cell activated': '0.6', 'Naive T-reg': '0.1'} | 1O6S, 2O72, 2OMT, 2OMU, 2OMV, 2OMX, 2OMY, 2OMZ, 3FF7, 3FF8, 3L6X, 3L6Y, 4ZT1, 4ZTE, 6CXY, 6OLE, 6OLF, 6OLG, 6VEL, 7STZ, 8H62 | {'Adipose Tissue': 1.2125261088039867, 'Adrenal Gland': 0.1914223992248062, 'Bladder': 39.2033519047619, 'Blood': 1.340954264800861, 'Blood Vessel': 0.3121561692883895, 'Brain': 0.8550442199091597, 'Breast': 38.54918344226579, 'Cervix Uteri': 23.539115789473684, 'Colon': 43.41292142490372, 'Esophagus': 53.97513367404844, 'Fallopian Tube': 14.900277777777776, 'Heart': 0.119140469221835, 'Kidney': 25.040449438202245, 'Liver': 26.60802654867257, 'Lung': 35.447986366782004, 'Muscle': 0.1378936151930261, 'Nerve': 17.518468982229404, 'Ovary': 3.6515122222222223, 'Pancreas': 56.89676829268293, 'Pituitary': 24.68741660777385, 'Prostate': 61.279967346938776, 'Salivary Gland': 92.01685185185184, 'Skin': 79.77571720232172, 'Small Intestine': 71.7519320855615, 'Spleen': 10.061029045643156, 'Stomach': 58.07813805013927, 'Testis': 0.8144204986149585, 'Thyroid': 135.176797856049, 'Uterus': 1.442593943661972, 'Vagina': 86.52345512820513} | NEUROD2 | MLTRLFSEPGLLSDVPKFASWGDGEDDEPRSDKGDAPPPPPPAPGPGAPGPARAAKPVPLRGEEGTEATLAEVKEEGELGGEEEEEEEEEEGLDEAEGERPKKRGPKKRKMTKARLERSKLRRQKANARERNRMHDLNAALDNLRKVVPCYSKTQKLSKIETLRLAKNYIWALSEILRSGKRPDLVSYVQTLCKGLSQPTTNLVAGCLQLNSRNFLTEQGADGAGRFHGSGGPFAMHPYPYPCSRLAGAQCQAAGGLGGGAAHALRTHGYCAAYETLYAAAGGGGASPDYNSSEYEGPLSPPLCLNGNFSLKQDSSPDHEKSYHYSMHYSALPGSRPTGHGLVFGSSAVRGGVHSENLLSYDMHLHHDRGPMYEELNAFFHN | Homo sapiens | Nucleus | Tissue enriched (brain) | {'Ciliated cells': '0.0', 'Basal respiratory cells': '0.1', 'Club cells': '0.1', 'Ionocytes': '0.0', 'Mucus glandular cells': '5.0', 'Serous glandular cells': '1.1', 'Gastric mucus-secreting cells': '0.0', 'Proximal enterocytes': '0.0', 'Paneth cells': '0.0', 'Distal enterocytes': '0.1', 'Intestinal goblet cells': '0.0', 'Exocrine glandular cells': '-0.007', 'Basal prostatic cells': '0.1', 'Prostatic glandular cells': '0.7', 'Breast glandular cells': '0.263', 'Breast myoepithelial cells': '0.359', 'Glandular and luminal cells': '0.2', 'Secretory cells': '0.0', 'Basal keratinocytes': '0.4', 'Suprabasal keratinocytes': '0.2', 'Basal squamous epithelial cells': '0.2', 'Squamous epithelial cells': '0.0', 'Alveolar cells type 1': '-0.025', 'Alveolar cells type 2': '-0.048', 'Salivary duct cells': '1.1', 'Ductal cells': '0.043', 'Hepatocytes': '0.008', 'Cholangiocytes': '0.0', 'Proximal tubular cells': '-0.001', 'Distal tubular cells': '0.0', 'Collecting duct cells': '0.0', 'Mesothelial cells': '0.027', 'Sertoli cells': '0.230', 'Granulosa cells': '0.0', 'Enteroendocrine cells': '5.0', 'Pancreatic endocrine cells': '0.0', 'Leydig cells': '0.062', 'Excitatory neurons': '14.4', 'Inhibitory neurons': '0.4', 'Cone photoreceptor cells': '0.0', 'Rod photoreceptor cells': '0.9', 'Bipolar cells': '7.7', 'Horizontal cells': '14.5', 'Astrocytes': '0.9', 'Oligodendrocyte precursor cells': '0.5', 'Oligodendrocytes': '0.9', 'Microglial cells': '1.8', 'Muller glia cells': '0.1', 'Schwann cells': '-0.057', 'Spermatogonia': '0.144', 'Spermatocytes': '0.044', 'Early spermatids': '-0.265', 'Late spermatids': '-0.136', 'Oocytes': '0.0', 'Cytotrophoblasts': '0.2', 'Syncytiotrophoblasts': '0.3', 'Extravillous trophoblasts': '0.2', 'Endothelial cells': '0.3', 'Lymphatic endothelial cells': '0.0', 'Cardiomyocytes': '0.153', 'Skeletal myocytes': '0.078', 'Smooth muscle cells': '0.1', 'Adipocytes': '0.1', 'Melanocytes': '0.203', 'Fibroblasts': '0.3', 'Peritubular cells': '0.062', 'Endometrial stromal cells': '0.2', 'Ovarian stromal cells': '0.2', 'Undifferentiated cells': '1.0', 'T-cells': '0.2', 'B-cells': '0.0', 'Plasma cells': '0.2', 'Nk-cells': '0.9', 'Granulocytes': '0.0', 'Monocytes': '0.0', 'Macrophages': '0.2', 'Hofbauer cells': '0.2', 'Kupffer cells': '0.3', 'Dendritic cells': '0.0', 'Langerhans cells': '0.435', 'Erythroid cells': '0.041', 'Adipocytes (Subcutaneous)': '-0.018', 'Adipocytes (Visceral)': '-0.052', 'Breast glandular cells (progenitors)': '0.171', 'Adipocytes (Breast)': '-0.267', 'Colon enterocytes': '-0.036', 'Colon 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0.93, 0.92, 0.86, 0.94, 0.59, 0.77, 0.94, 0.89, 0.86, 0.93, 0.85, 0.95, 0.85, 0.96, 0.95, 0.98, 1.0] | null | Component of an E-cadherin/ catenin adhesion complex composed of at least E-cadherin/CDH1, beta-catenin/CTNNB1 or gamma-catenin/JUP, and potentially alpha-catenin/CTNNA1. Forms a ternary complex composed of ADAM10, CADH1 and EPHA4, | null | null | KLRG1, SPEF1, DLGAP5, AJAP1, RAPGEF2, RAB8B, PIP5K1C, PKP2, TRPV4, CTNNB1, CAV1, DDR1, TBC1D2, CTNNA1, JUP, CTNND1, PSEN1, LIMA1, CDH1, JUP, ADAM10, CADH1 , EPHA4, | null | null | null | null | Homodimer | null | 79.91949 | 0.474025 | 59.993743 | 0.789136 | 2,038 |
P12830 | Q16875 | null | degron_data | CDH1 | MGPWSRSLSALLLLLQVSSWLCQEPEPCHPGFDAESYTFTVPRRHLERGRVLGRVNFEDCTGRQRTAYFSLDTRFKVGTDGVITVKRPLRFHNPQIHFLVYAWDSTYRKFSTKVTLNTVGHHHRPPPHQASVSGIQAELLTFPNSSPGLRRQKRDWVIPPISCPENEKGPFPKNLVQIKSNKDKEGKVFYSITGQGADTPPVGVFIIERETGWLKVTEPLDRERIATYTLFSHAVSSNGNAVEDPMEILITVTDQNDNKPEFTQEVFKGSVMEGALPGTSVMEVTATDADDDVNTYNAAIAYTILSQDPELPDKNMFTINRNTGVISVVTTGLDRESFPTYTLVVQAADLQGEGLSTTATAVITVTDTNDNPPIFNPTTYKGQVPENEANVVITTLKVTDADAPNTPAWEAVYTILNDDGGQFVVTTNPVNNDGILKTAKGLDFEAKQQYILHVAVTNVVPFEVSLTTSTATVTVDVLDVNEAPIFVPPEKRVEVSEDFGVGQEITSYTAQEPDTFMEQKITYRIWRDTANWLEINPDTGAISTRAELDREDFEHVKNSTYTALIIATDNGSPVATGTGTLLLILSDVNDNAPIPEPRTIFFCERNPKPQVINIIDADLPPNTSPFTAELTHGASANWTIQYNDPTQESIILKPKMALEVGDYKINLKLMDNQNKDQVTTLEVSVCDCEGAAGVCRKAQPVEAGLQIPAILGILGGILALLILILLLLLFLRRRAVVKEPLLPPEDDTRDNVYYYDEEGGGEEDQDFDLSQLHRGLDARPEVTRNDVAPTLMSVPRYLPRPANPDEIGNFIDENLKAADTDPTAPPYDSLLVFDYEGSGSEAASLSSLNSSESDKDQDYDYLNEWGNRFKKLADMYGGGEDD | Homo sapiens | Cell junction, adherens junction, Cell membrane, Endosome, Golgi apparatus, trans-Golgi network, Cytoplasm, Cell junction, desmosome | Tissue enhanced (parathyroid) | {'Ciliated cells': '119.1', 'Basal respiratory cells': '71.1', 'Club cells': '97.3', 'Ionocytes': '81.0', 'Mucus glandular cells': '155.0', 'Serous glandular cells': '67.8', 'Gastric mucus-secreting cells': '133.2', 'Proximal enterocytes': '140.9', 'Paneth cells': '125.1', 'Distal enterocytes': '307.5', 'Intestinal goblet cells': '173.5', 'Exocrine glandular cells': '-0.605', 'Basal prostatic cells': '68.3', 'Prostatic glandular cells': '186.7', 'Breast glandular cells': '0.773', 'Breast myoepithelial cells': '0.700', 'Glandular and luminal cells': '313.0', 'Secretory cells': '82.3', 'Basal keratinocytes': '102.5', 'Suprabasal keratinocytes': '162.6', 'Basal squamous epithelial cells': '51.0', 'Squamous epithelial cells': '106.9', 'Alveolar cells type 1': '0.437', 'Alveolar cells type 2': '0.706', 'Salivary duct cells': '95.9', 'Ductal cells': '0.541', 'Hepatocytes': '0.600', 'Cholangiocytes': '129.7', 'Proximal tubular cells': '0.042', 'Distal tubular cells': '0.0', 'Collecting duct cells': '143.9', 'Mesothelial cells': '0.799', 'Sertoli cells': '0.252', 'Granulosa cells': '12.9', 'Enteroendocrine cells': '92.4', 'Pancreatic endocrine cells': '78.1', 'Leydig cells': '0.264', 'Excitatory neurons': '0.7', 'Inhibitory neurons': '1.3', 'Cone photoreceptor cells': '0.0', 'Rod photoreceptor cells': '0.0', 'Bipolar cells': '0.2', 'Horizontal cells': '0.6', 'Astrocytes': '0.6', 'Oligodendrocyte precursor cells': '0.5', 'Oligodendrocytes': '29.9', 'Microglial cells': '0.9', 'Muller glia cells': '0.1', 'Schwann cells': '0.131', 'Spermatogonia': '0.392', 'Spermatocytes': '0.193', 'Early spermatids': '-0.217', 'Late spermatids': '-0.290', 'Oocytes': '16.9', 'Cytotrophoblasts': '119.2', 'Syncytiotrophoblasts': '45.0', 'Extravillous trophoblasts': '24.9', 'Endothelial cells': '6.1', 'Lymphatic endothelial cells': '0.4', 'Cardiomyocytes': '0.135', 'Skeletal myocytes': '0.107', 'Smooth muscle cells': '5.8', 'Adipocytes': '2.1', 'Melanocytes': '0.335', 'Fibroblasts': '6.5', 'Peritubular cells': '0.210', 'Endometrial stromal cells': '27.7', 'Ovarian stromal cells': '0.7', 'Undifferentiated cells': '101.6', 'T-cells': '2.9', 'B-cells': '4.4', 'Plasma cells': '6.1', 'Nk-cells': '0.0', 'Granulocytes': '8.4', 'Monocytes': '0.0', 'Macrophages': '6.0', 'Hofbauer cells': '4.3', 'Kupffer cells': '1.0', 'Dendritic cells': '5.9', 'Langerhans cells': '0.304', 'Erythroid cells': '0.036', 'Adipocytes (Subcutaneous)': '-0.081', 'Adipocytes (Visceral)': '-0.209', 'Breast glandular cells (progenitors)': '0.538', 'Adipocytes (Breast)': '-0.689', 'Colon enterocytes': '0.790', 'Colon enteroendocrine cells': '0.112', 'Enteric glia cells': '-0.048', 'Mitotic cells (Colon)': '0.299', 'Mitotic cells (Heart)': '0.120', 'Podocytes': '-0.118', 'Ascending Loop of Henle cells': '0.475', 'Intercalated cells': '0.212', 'Cholangiocyte': '0.090', 'NK-cells (Liver)': '-0.005', 'Respiratory ciliated cells': '-0.012', 'Mitotic cells (Lung)': '0.071', 'NK-cells (Lung)': '-0.266', 'B-cells (Lung)': '-0.296', 'Alpha cells': '0.270', 'Beta cells': '0.152', 'Prostate glandular cells': '0.764', 'Prostate basal glandular cells': '0.540', 'Urothelial cells': '0.205', 'Keratinocyte (other)': '0.510', 'Keratinocyte (granular)': '0.055', 'Hair cortex cells': '0.080', 'Inner root sheath cells': '0.131', 'Outer root sheath cells': '0.175', 'Sebaceous gland cells': '0.156', 'Eccrine sweat gland cells': '-0.207', 'Adipocytes (Skin)': '-0.244', 'Mitotic cells (Skin)': '0.442', 'Parietal cells': '0.654', 'Chief cells': '0.649', 'Gastric mucous cells': '0.781', 'Gastric enteroendocrine cells': '0.590', 'Mitotic cells (Stomach)': '0.445', 'Parafollicular cells': '0.173', 'Thyroid glandular cells': '0.865', 'Mitotic cells (Thyroid)': '-0.081', 'Adrenal cortex cells': '0.051', 'Adrenal medulla cells': '0.087', 'Mitotic cells (Adrenal gland)': '0.072', 'Minor salivary glandular cells': '0.371', 'Minor salivary gland ductal cells': '-0.142', 'Minor salivary gland basal cells': '0.582', 'Mitotic cells (Minor salivary gland)': '0.567', 'Adipocytes (Minor salivary gland)': '0.050', 'Somatotropes': '0.121', 'Lactotropes': '0.322', 'Gonadotropes': '0.330', 'Corticotropes': '0.180', 'Thyrotropes': '0.496', 'Undifferentiated cells (Pituitary gland)': '-0.108', 'Mitotic cells (Spleen)': '-0.228', 'Platelets': '-0.050', 'Erythrocytes': '-0.158', 'Hematopoietic stem cells': '-0.211', 'B-cells (Spleen)': '0.266', 'NK-cells (Spleen)': '0.309', 'Amygdala excitatory': '1.0', 'Cerebellar inhibitory': '0.9', 'Cge interneuron': '0.7', 'Deep-layer corticothalamic and 6b': '1.5', 'Deep-layer intratelencephalic': '0.7', 'Deep-layer near-projecting': '0.7', 'Eccentric medium spiny neuron': '0.6', 'Hippocampal ca1-3': '1.9', 'Hippocampal ca4': '1.2', 'Hippocampal dentate gyrus': '1.1', 'Lamp5-lhx6 and chandelier': '0.5', 'Lower rhombic lip': '0.8', 'Mammillary body': '0.6', 'Medium spiny neuron': '0.7', 'Mge interneuron': '1.7', 'Midbrain-derived inhibitory': '0.7', 'Miscellaneous': '0.9', 'Splatter': '3.8', 'Thalamic excitatory': '0.5', 'Upper rhombic lip': '0.8', 'Upper-layer intratelencephalic': '0.6', 'Astrocyte': '4.4', 'Bergmann glia': '0.2', 'Central nervous system macrophage': '0.6', 'Choroid plexus epithelial cell': '52.1', 'Committed oligodendrocyte precursor': '41.5', 'Ependymal cell': '4.8', 'Oligodendrocyte': '53.1', 'Oligodendrocyte precursor cell': '2.4', 'Endothelial cell': '0.7', 'Pericyte': '0.3', 'Vascular associated smooth muscle cell': '0.0', 'Fibroblast': '17.4', 'Leukocyte': '1.1', 'Basophil': '0.0', 'Eosinophil': '0.0', 'Neutrophil': '0.0', 'Classical monocyte': '0.0', 'Non-classical monocyte': '0.0', 'Intermediate monocyte': '0.0', 'T-reg': '2.3', 'GdT-cell': '0.0', 'MAIT T-cell': '0.0', 'Memory CD4 T-cell': '0.0', 'Naive CD4 T-cell': '0.1', 'Memory CD8 T-cell': '0.2', 'Naive CD8 T-cell': '0.3', 'Memory B-cell': '0.0', 'Naive B-cell': '0.1', 'Plasmacytoid DC': '46.6', 'Myeloid DC': '8.5', 'NK-cell': '0.1', 'Total PBMC': '0.7', 'Vd2 gdTCR': '0.0', 'Memory CD4 T-cell Th1\\/Th17': '0.1', 'Memory CD4 T-cell Th17': '0.2', 'Memory CD4 T-cell Th2': '2.9', 'Non-Vd2 gdTCR': '0.1', 'Memory CD4 T-cell Th1': '0.3', 'Memory CD4 T-cell TFH': '0.5', 'Terminal effector memory CD4 T-cell': '0.0', 'Central memory CD8 T-cell': '4.8', 'Effector memory CD8 T-cell': '0.0', 'Terminal effector memory CD8 T-cell': '0.6', 'Non-switched memory B-cell': '0.0', 'Plasmablast': '3.3', 'Switched memory B-cell': '0.0', 'Exhausted memory B-cell': '0.7', 'Progenitor cell': '2.3', 'Memory T-reg': '1.3', 'Naive CD4 T-cell activated': '0.3', 'Naive CD8 T-cell activated': '0.6', 'Naive T-reg': '0.1'} | 1O6S, 2O72, 2OMT, 2OMU, 2OMV, 2OMX, 2OMY, 2OMZ, 3FF7, 3FF8, 3L6X, 3L6Y, 4ZT1, 4ZTE, 6CXY, 6OLE, 6OLF, 6OLG, 6VEL, 7STZ, 8H62 | {'Adipose Tissue': 1.2125261088039867, 'Adrenal Gland': 0.1914223992248062, 'Bladder': 39.2033519047619, 'Blood': 1.340954264800861, 'Blood Vessel': 0.3121561692883895, 'Brain': 0.8550442199091597, 'Breast': 38.54918344226579, 'Cervix Uteri': 23.539115789473684, 'Colon': 43.41292142490372, 'Esophagus': 53.97513367404844, 'Fallopian Tube': 14.900277777777776, 'Heart': 0.119140469221835, 'Kidney': 25.040449438202245, 'Liver': 26.60802654867257, 'Lung': 35.447986366782004, 'Muscle': 0.1378936151930261, 'Nerve': 17.518468982229404, 'Ovary': 3.6515122222222223, 'Pancreas': 56.89676829268293, 'Pituitary': 24.68741660777385, 'Prostate': 61.279967346938776, 'Salivary Gland': 92.01685185185184, 'Skin': 79.77571720232172, 'Small Intestine': 71.7519320855615, 'Spleen': 10.061029045643156, 'Stomach': 58.07813805013927, 'Testis': 0.8144204986149585, 'Thyroid': 135.176797856049, 'Uterus': 1.442593943661972, 'Vagina': 86.52345512820513} | PFKFB3 | MPLELTQSRVQKIWVPVDHRPSLPRSCGPKLTNSPTVIVMVGLPARGKTYISKKLTRYLNWIGVPTKVFNVGEYRREAVKQYSSYNFFRPDNEEAMKVRKQCALAALRDVKSYLAKEGGQIAVFDATNTTRERRHMILHFAKENDFKAFFIESVCDDPTVVASNIMEVKISSPDYKDCNSAEAMDDFMKRISCYEASYQPLDPDKCDRDLSLIKVIDVGRRFLVNRVQDHIQSRIVYYLMNIHVQPRTIYLCRHGENEHNLQGRIGGDSGLSSRGKKFASALSKFVEEQNLKDLRVWTSQLKSTIQTAEALRLPYEQWKALNEIDAGVCEELTYEEIRDTYPEEYALREQDKYYYRYPTGESYQDLVQRLEPVIMELERQENVLVICHQAVLRCLLAYFLDKSAEEMPYLKCPLHTVLKLTPVAYGCRVESIYLNVESVCTHRERSEDAKKGPNPLMRRNSVTPLASPEPTKKPRINSFEEHVASTSAALPSCLPPEVPTQLPGQNMKGSRSSADSSRKH | Homo sapiens | null | Tissue enhanced (adipose tissue, skeletal muscle) | {'Ciliated cells': '28.1', 'Basal respiratory cells': '22.0', 'Club cells': '17.9', 'Ionocytes': '17.3', 'Mucus glandular cells': '23.4', 'Serous glandular cells': '10.3', 'Gastric mucus-secreting cells': '26.5', 'Proximal enterocytes': '6.5', 'Paneth cells': '5.2', 'Distal enterocytes': '5.6', 'Intestinal goblet cells': '6.1', 'Exocrine glandular cells': '-0.635', 'Basal prostatic cells': '63.9', 'Prostatic glandular cells': '3.9', 'Breast glandular cells': '-0.406', 'Breast myoepithelial cells': '-0.418', 'Glandular and luminal cells': '61.8', 'Secretory cells': '20.1', 'Basal keratinocytes': '69.6', 'Suprabasal keratinocytes': '45.0', 'Basal squamous epithelial cells': '28.4', 'Squamous epithelial cells': '18.9', 'Alveolar cells type 1': '0.120', 'Alveolar cells type 2': '-0.309', 'Salivary duct cells': '35.2', 'Ductal cells': '0.505', 'Hepatocytes': '0.088', 'Cholangiocytes': '22.9', 'Proximal tubular cells': '-0.192', 'Distal tubular cells': '0.0', 'Collecting duct cells': '184.8', 'Mesothelial cells': '-0.252', 'Sertoli cells': '0.525', 'Granulosa cells': '16.3', 'Enteroendocrine cells': '14.2', 'Pancreatic endocrine cells': '20.4', 'Leydig cells': '0.545', 'Excitatory neurons': '41.4', 'Inhibitory neurons': '18.6', 'Cone photoreceptor cells': '39.1', 'Rod photoreceptor cells': '3.6', 'Bipolar cells': '7.9', 'Horizontal cells': '10.7', 'Astrocytes': '145.8', 'Oligodendrocyte precursor cells': '13.2', 'Oligodendrocytes': '29.7', 'Microglial cells': '39.4', 'Muller glia cells': '6.1', 'Schwann cells': '-0.047', 'Spermatogonia': '0.299', 'Spermatocytes': '-0.074', 'Early spermatids': '-0.397', 'Late spermatids': '-0.512', 'Oocytes': '8.1', 'Cytotrophoblasts': '0.4', 'Syncytiotrophoblasts': '0.7', 'Extravillous trophoblasts': '7.7', 'Endothelial cells': '24.3', 'Lymphatic endothelial cells': '8.6', 'Cardiomyocytes': '0.234', 'Skeletal myocytes': '-0.148', 'Smooth muscle cells': '19.7', 'Adipocytes': '33.3', 'Melanocytes': '-0.165', 'Fibroblasts': '24.7', 'Peritubular cells': '0.444', 'Endometrial stromal cells': '18.1', 'Ovarian stromal cells': '5.6', 'Undifferentiated cells': '7.0', 'T-cells': '79.7', 'B-cells': '28.3', 'Plasma cells': '20.6', 'Nk-cells': '38.3', 'Granulocytes': '36.4', 'Monocytes': '329.1', 'Macrophages': '138.1', 'Hofbauer cells': '59.8', 'Kupffer cells': '83.9', 'Dendritic cells': '163.5', 'Langerhans cells': '-0.213', 'Erythroid cells': '0.034', 'Adipocytes (Subcutaneous)': '0.764', 'Adipocytes (Visceral)': '0.740', 'Breast glandular cells (progenitors)': '-0.264', 'Adipocytes (Breast)': '0.821', 'Colon enterocytes': '-0.113', 'Colon enteroendocrine cells': '0.250', 'Enteric glia cells': '0.226', 'Mitotic cells (Colon)': '0.019', 'Mitotic cells (Heart)': '0.321', 'Podocytes': '-0.371', 'Ascending Loop of Henle cells': '0.381', 'Intercalated cells': '-0.224', 'Cholangiocyte': '0.338', 'NK-cells (Liver)': '-0.310', 'Respiratory ciliated cells': '-0.008', 'Mitotic cells (Lung)': '-0.169', 'NK-cells (Lung)': '0.380', 'B-cells (Lung)': '0.260', 'Alpha cells': '0.303', 'Beta cells': '0.154', 'Prostate glandular cells': '-0.287', 'Prostate basal glandular cells': '0.122', 'Urothelial cells': '0.262', 'Keratinocyte (other)': '-0.314', 'Keratinocyte (granular)': '-0.339', 'Hair cortex cells': '0.310', 'Inner root sheath cells': '0.282', 'Outer root sheath cells': '0.366', 'Sebaceous gland cells': '-0.123', 'Eccrine sweat gland cells': '0.651', 'Adipocytes (Skin)': '0.303', 'Mitotic cells (Skin)': '0.056', 'Parietal cells': '-0.421', 'Chief cells': '-0.375', 'Gastric mucous cells': '-0.110', 'Gastric enteroendocrine cells': '-0.209', 'Mitotic cells (Stomach)': '0.051', 'Parafollicular cells': '0.002', 'Thyroid glandular cells': '-0.178', 'Mitotic cells (Thyroid)': '0.250', 'Adrenal cortex cells': '0.203', 'Adrenal medulla cells': '-0.126', 'Mitotic cells (Adrenal gland)': '-0.210', 'Minor salivary glandular cells': '0.207', 'Minor salivary gland ductal cells': '0.072', 'Minor salivary gland basal cells': '0.303', 'Mitotic cells (Minor salivary gland)': '0.243', 'Adipocytes (Minor salivary gland)': '0.240', 'Somatotropes': '-0.260', 'Lactotropes': '-0.067', 'Gonadotropes': '0.082', 'Corticotropes': '-0.002', 'Thyrotropes': '0.137', 'Undifferentiated cells (Pituitary gland)': '0.062', 'Mitotic cells (Spleen)': '-0.237', 'Platelets': '-0.120', 'Erythrocytes': '-0.216', 'Hematopoietic stem cells': '-0.062', 'B-cells (Spleen)': '0.091', 'NK-cells (Spleen)': '0.124', 'Amygdala excitatory': '72.2', 'Cerebellar inhibitory': '34.7', 'Cge interneuron': '12.1', 'Deep-layer corticothalamic and 6b': '44.0', 'Deep-layer intratelencephalic': '71.8', 'Deep-layer near-projecting': '49.5', 'Eccentric medium spiny neuron': '35.4', 'Hippocampal ca1-3': '46.5', 'Hippocampal ca4': '39.6', 'Hippocampal dentate gyrus': '62.1', 'Lamp5-lhx6 and chandelier': '28.2', 'Lower rhombic lip': '49.4', 'Mammillary body': '53.8', 'Medium spiny neuron': '32.5', 'Mge interneuron': '40.6', 'Midbrain-derived inhibitory': '7.8', 'Miscellaneous': '49.1', 'Splatter': '31.6', 'Thalamic excitatory': '34.3', 'Upper rhombic lip': '26.6', 'Upper-layer intratelencephalic': '83.2', 'Astrocyte': '401.0', 'Bergmann glia': '213.6', 'Central nervous system macrophage': '240.7', 'Choroid plexus epithelial cell': '15.8', 'Committed oligodendrocyte precursor': '35.9', 'Ependymal cell': '114.2', 'Oligodendrocyte': '46.8', 'Oligodendrocyte precursor cell': '33.4', 'Endothelial cell': '38.8', 'Pericyte': '52.8', 'Vascular associated smooth muscle cell': '38.1', 'Fibroblast': '72.3', 'Leukocyte': '79.2', 'Basophil': '49.2', 'Eosinophil': '7.8', 'Neutrophil': '351.4', 'Classical monocyte': '297.4', 'Non-classical monocyte': '141.6', 'Intermediate monocyte': '284.0', 'T-reg': '25.1', 'GdT-cell': '2.2', 'MAIT T-cell': '36.0', 'Memory CD4 T-cell': '4.2', 'Naive CD4 T-cell': '21.1', 'Memory CD8 T-cell': '2.9', 'Naive CD8 T-cell': '26.8', 'Memory B-cell': '1.8', 'Naive B-cell': '10.6', 'Plasmacytoid DC': '13.0', 'Myeloid DC': '51.9', 'NK-cell': '13.5', 'Total PBMC': '59.5', 'Vd2 gdTCR': '20.8', 'Memory CD4 T-cell Th1\\/Th17': '87.1', 'Memory CD4 T-cell Th17': '79.9', 'Memory CD4 T-cell Th2': '44.2', 'Non-Vd2 gdTCR': '12.3', 'Memory CD4 T-cell Th1': '69.5', 'Memory CD4 T-cell TFH': '64.8', 'Terminal effector memory CD4 T-cell': '14.0', 'Central memory CD8 T-cell': '32.2', 'Effector memory CD8 T-cell': '15.5', 'Terminal effector memory CD8 T-cell': '10.3', 'Non-switched memory B-cell': '19.5', 'Plasmablast': '13.6', 'Switched memory B-cell': '15.2', 'Exhausted memory B-cell': '20.0', 'Progenitor cell': '23.9', 'Memory T-reg': '55.6', 'Naive CD4 T-cell activated': '338.1', 'Naive CD8 T-cell activated': '206.6', 'Naive T-reg': '24.5'} | 2AXN, 2DWO, 2DWP, 2I1V, 3QPU, 3QPV, 3QPW, 4D4J, 4D4K, 4D4L, 4D4M, 4MA4, 5AJV, 5AJW, 5AJX, 5AJY, 5AJZ, 5AK0, 6ETJ, 6HVH, 6HVI, 6HVJ, 6IBX, 6IBY, 6IBZ, 6IC0 | {'Adipose Tissue': 264.88431063122925, 'Adrenal Gland': 20.997612403100774, 'Bladder': 38.70857142857143, 'Blood': 137.5398934337998, 'Blood Vessel': 95.86592359550562, 'Brain': 44.32595344436033, 'Breast': 191.20278867102397, 'Cervix Uteri': 35.99947368421053, 'Colon': 25.623186136071887, 'Esophagus': 39.86713494809689, 'Fallopian Tube': 51.22222222222222, 'Heart': 11.82161231126597, 'Kidney': 72.43587640449438, 'Liver': 18.221929203539823, 'Lung': 106.3375259515571, 'Muscle': 368.3814084682441, 'Nerve': 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29.32, 31.48, 34.34, 30.38, 31.7, 35.19, 35.38, 35.42, 36.67, 32.3, 39.72, 34.22, 35.85, 36.97, 46.38, 42.98, 37.02, 35.11, 43.5, 38.6, 38.1, 40.67, 44.85, 38.77, 39.2, 39.02, 39.24, 42.22, 40.05, 41.27, 40.65, 41.94, 41.91, 42.93, 43.44, 42.74, 42.51, 44.76, 49.14, 53.82] | [0.75, 0.99, 0.89, 0.36, 0.54, 0.46, 0.43, 0.36, 0.58, 0.29, 0.42, 0.12, 0.44, 0.63, 0.44, 0.74, 0.31, 0.6, 0.7, 0.66, 0.69, 0.94, 0.84, 0.6, 0.92, 0.91, 0.89, 0.66, 0.7, 0.88, 0.45, 0.94, 0.72, 0.47, 0.16, 0.02, 0.01, 0.0, 0.0, 0.0, 0.0, 0.0, 0.05, 0.12, 0.09, 0.09, 0.3, 0.08, 0.23, 0.25, 0.07, 0.0, 0.41, 0.09, 0.0, 0.11, 0.11, 0.0, 0.0, 0.23, 0.05, 0.21, 0.54, 0.15, 0.02, 0.0, 0.39, 0.31, 0.02, 0.15, 0.1, 0.26, 0.47, 0.19, 0.07, 0.35, 0.47, 0.47, 0.25, 0.9, 0.84, 0.21, 0.91, 0.29, 0.33, 0.44, 0.2, 0.07, 0.39, 0.47, 0.63, 0.33, 0.77, 0.49, 0.06, 0.41, 0.41, 0.2, 0.11, 0.44, 0.43, 0.07, 0.01, 0.46, 0.26, 0.0, 0.02, 0.69, 0.4, 0.0, 0.45, 0.28, 0.02, 0.07, 0.69, 0.7, 0.4, 0.23, 0.0, 0.3, 0.02, 0.0, 0.0, 0.0, 0.03, 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0.59, 0.85, 0.92, 0.92, 0.55, 0.85, 0.73, 0.84, 0.76, 0.68, 0.87, 0.97, 0.99, 0.99, 0.98, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 0.99, 0.99, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0] | null | Component of an E-cadherin/ catenin adhesion complex composed of at least E-cadherin/CDH1, beta-catenin/CTNNB1 or gamma-catenin/JUP, and potentially alpha-catenin/CTNNA1. Forms a ternary complex composed of ADAM10, CADH1 and EPHA4, | null | null | KLRG1, SPEF1, DLGAP5, AJAP1, RAPGEF2, RAB8B, PIP5K1C, PKP2, TRPV4, CTNNB1, CAV1, DDR1, TBC1D2, CTNNA1, JUP, CTNND1, PSEN1, LIMA1, CDH1, JUP, ADAM10, CADH1 , EPHA4, | null | null | null | null | Homodimer | null | 79.91949 | 0.474025 | 86.458327 | 0.376058 | 1,509 |
P12830 | Q5FBB7 | null | degron_data | CDH1 | MGPWSRSLSALLLLLQVSSWLCQEPEPCHPGFDAESYTFTVPRRHLERGRVLGRVNFEDCTGRQRTAYFSLDTRFKVGTDGVITVKRPLRFHNPQIHFLVYAWDSTYRKFSTKVTLNTVGHHHRPPPHQASVSGIQAELLTFPNSSPGLRRQKRDWVIPPISCPENEKGPFPKNLVQIKSNKDKEGKVFYSITGQGADTPPVGVFIIERETGWLKVTEPLDRERIATYTLFSHAVSSNGNAVEDPMEILITVTDQNDNKPEFTQEVFKGSVMEGALPGTSVMEVTATDADDDVNTYNAAIAYTILSQDPELPDKNMFTINRNTGVISVVTTGLDRESFPTYTLVVQAADLQGEGLSTTATAVITVTDTNDNPPIFNPTTYKGQVPENEANVVITTLKVTDADAPNTPAWEAVYTILNDDGGQFVVTTNPVNNDGILKTAKGLDFEAKQQYILHVAVTNVVPFEVSLTTSTATVTVDVLDVNEAPIFVPPEKRVEVSEDFGVGQEITSYTAQEPDTFMEQKITYRIWRDTANWLEINPDTGAISTRAELDREDFEHVKNSTYTALIIATDNGSPVATGTGTLLLILSDVNDNAPIPEPRTIFFCERNPKPQVINIIDADLPPNTSPFTAELTHGASANWTIQYNDPTQESIILKPKMALEVGDYKINLKLMDNQNKDQVTTLEVSVCDCEGAAGVCRKAQPVEAGLQIPAILGILGGILALLILILLLLLFLRRRAVVKEPLLPPEDDTRDNVYYYDEEGGGEEDQDFDLSQLHRGLDARPEVTRNDVAPTLMSVPRYLPRPANPDEIGNFIDENLKAADTDPTAPPYDSLLVFDYEGSGSEAASLSSLNSSESDKDQDYDYLNEWGNRFKKLADMYGGGEDD | Homo sapiens | Cell junction, adherens junction, Cell membrane, Endosome, Golgi apparatus, trans-Golgi network, Cytoplasm, Cell junction, desmosome | Tissue enhanced (parathyroid) | {'Ciliated cells': '119.1', 'Basal respiratory cells': '71.1', 'Club cells': '97.3', 'Ionocytes': '81.0', 'Mucus glandular cells': '155.0', 'Serous glandular cells': '67.8', 'Gastric mucus-secreting cells': '133.2', 'Proximal enterocytes': '140.9', 'Paneth cells': '125.1', 'Distal enterocytes': '307.5', 'Intestinal goblet cells': '173.5', 'Exocrine glandular cells': '-0.605', 'Basal prostatic cells': '68.3', 'Prostatic glandular cells': '186.7', 'Breast glandular cells': '0.773', 'Breast myoepithelial cells': '0.700', 'Glandular and luminal cells': '313.0', 'Secretory cells': '82.3', 'Basal keratinocytes': '102.5', 'Suprabasal keratinocytes': '162.6', 'Basal squamous epithelial cells': '51.0', 'Squamous epithelial cells': '106.9', 'Alveolar cells type 1': '0.437', 'Alveolar cells type 2': '0.706', 'Salivary duct cells': '95.9', 'Ductal cells': '0.541', 'Hepatocytes': '0.600', 'Cholangiocytes': '129.7', 'Proximal tubular cells': '0.042', 'Distal tubular cells': '0.0', 'Collecting duct cells': '143.9', 'Mesothelial cells': '0.799', 'Sertoli cells': '0.252', 'Granulosa cells': '12.9', 'Enteroendocrine cells': '92.4', 'Pancreatic endocrine cells': '78.1', 'Leydig cells': '0.264', 'Excitatory neurons': '0.7', 'Inhibitory neurons': '1.3', 'Cone photoreceptor cells': '0.0', 'Rod photoreceptor cells': '0.0', 'Bipolar cells': '0.2', 'Horizontal cells': '0.6', 'Astrocytes': '0.6', 'Oligodendrocyte precursor cells': '0.5', 'Oligodendrocytes': '29.9', 'Microglial cells': '0.9', 'Muller glia cells': '0.1', 'Schwann cells': '0.131', 'Spermatogonia': '0.392', 'Spermatocytes': '0.193', 'Early spermatids': '-0.217', 'Late spermatids': '-0.290', 'Oocytes': '16.9', 'Cytotrophoblasts': '119.2', 'Syncytiotrophoblasts': '45.0', 'Extravillous trophoblasts': '24.9', 'Endothelial cells': '6.1', 'Lymphatic endothelial cells': '0.4', 'Cardiomyocytes': '0.135', 'Skeletal myocytes': '0.107', 'Smooth muscle cells': '5.8', 'Adipocytes': '2.1', 'Melanocytes': '0.335', 'Fibroblasts': '6.5', 'Peritubular cells': '0.210', 'Endometrial stromal cells': '27.7', 'Ovarian stromal cells': '0.7', 'Undifferentiated cells': '101.6', 'T-cells': '2.9', 'B-cells': '4.4', 'Plasma cells': '6.1', 'Nk-cells': '0.0', 'Granulocytes': '8.4', 'Monocytes': '0.0', 'Macrophages': '6.0', 'Hofbauer cells': '4.3', 'Kupffer cells': '1.0', 'Dendritic cells': '5.9', 'Langerhans cells': '0.304', 'Erythroid cells': '0.036', 'Adipocytes (Subcutaneous)': '-0.081', 'Adipocytes (Visceral)': '-0.209', 'Breast glandular cells (progenitors)': '0.538', 'Adipocytes (Breast)': '-0.689', 'Colon enterocytes': '0.790', 'Colon enteroendocrine cells': '0.112', 'Enteric glia cells': '-0.048', 'Mitotic cells (Colon)': '0.299', 'Mitotic cells (Heart)': '0.120', 'Podocytes': '-0.118', 'Ascending Loop of Henle cells': '0.475', 'Intercalated cells': '0.212', 'Cholangiocyte': '0.090', 'NK-cells (Liver)': '-0.005', 'Respiratory ciliated cells': '-0.012', 'Mitotic cells (Lung)': '0.071', 'NK-cells (Lung)': '-0.266', 'B-cells (Lung)': '-0.296', 'Alpha cells': '0.270', 'Beta cells': '0.152', 'Prostate glandular cells': '0.764', 'Prostate basal glandular cells': '0.540', 'Urothelial cells': '0.205', 'Keratinocyte (other)': '0.510', 'Keratinocyte (granular)': '0.055', 'Hair cortex cells': '0.080', 'Inner root sheath cells': '0.131', 'Outer root sheath cells': '0.175', 'Sebaceous gland cells': '0.156', 'Eccrine sweat gland cells': '-0.207', 'Adipocytes (Skin)': '-0.244', 'Mitotic cells (Skin)': '0.442', 'Parietal cells': '0.654', 'Chief cells': '0.649', 'Gastric mucous cells': '0.781', 'Gastric enteroendocrine cells': '0.590', 'Mitotic cells (Stomach)': '0.445', 'Parafollicular cells': '0.173', 'Thyroid glandular cells': '0.865', 'Mitotic cells (Thyroid)': '-0.081', 'Adrenal cortex cells': '0.051', 'Adrenal medulla cells': '0.087', 'Mitotic cells (Adrenal gland)': '0.072', 'Minor salivary glandular cells': '0.371', 'Minor salivary gland ductal cells': '-0.142', 'Minor salivary gland basal cells': '0.582', 'Mitotic cells (Minor salivary gland)': '0.567', 'Adipocytes (Minor salivary gland)': '0.050', 'Somatotropes': '0.121', 'Lactotropes': '0.322', 'Gonadotropes': '0.330', 'Corticotropes': '0.180', 'Thyrotropes': '0.496', 'Undifferentiated cells (Pituitary gland)': '-0.108', 'Mitotic cells (Spleen)': '-0.228', 'Platelets': '-0.050', 'Erythrocytes': '-0.158', 'Hematopoietic stem cells': '-0.211', 'B-cells (Spleen)': '0.266', 'NK-cells (Spleen)': '0.309', 'Amygdala excitatory': '1.0', 'Cerebellar inhibitory': '0.9', 'Cge interneuron': '0.7', 'Deep-layer corticothalamic and 6b': '1.5', 'Deep-layer intratelencephalic': '0.7', 'Deep-layer near-projecting': '0.7', 'Eccentric medium spiny neuron': '0.6', 'Hippocampal ca1-3': '1.9', 'Hippocampal ca4': '1.2', 'Hippocampal dentate gyrus': '1.1', 'Lamp5-lhx6 and chandelier': '0.5', 'Lower rhombic lip': '0.8', 'Mammillary body': '0.6', 'Medium spiny neuron': '0.7', 'Mge interneuron': '1.7', 'Midbrain-derived inhibitory': '0.7', 'Miscellaneous': '0.9', 'Splatter': '3.8', 'Thalamic excitatory': '0.5', 'Upper rhombic lip': '0.8', 'Upper-layer intratelencephalic': '0.6', 'Astrocyte': '4.4', 'Bergmann glia': '0.2', 'Central nervous system macrophage': '0.6', 'Choroid plexus epithelial cell': '52.1', 'Committed oligodendrocyte precursor': '41.5', 'Ependymal cell': '4.8', 'Oligodendrocyte': '53.1', 'Oligodendrocyte precursor cell': '2.4', 'Endothelial cell': '0.7', 'Pericyte': '0.3', 'Vascular associated smooth muscle cell': '0.0', 'Fibroblast': '17.4', 'Leukocyte': '1.1', 'Basophil': '0.0', 'Eosinophil': '0.0', 'Neutrophil': '0.0', 'Classical monocyte': '0.0', 'Non-classical monocyte': '0.0', 'Intermediate monocyte': '0.0', 'T-reg': '2.3', 'GdT-cell': '0.0', 'MAIT T-cell': '0.0', 'Memory CD4 T-cell': '0.0', 'Naive CD4 T-cell': '0.1', 'Memory CD8 T-cell': '0.2', 'Naive CD8 T-cell': '0.3', 'Memory B-cell': '0.0', 'Naive B-cell': '0.1', 'Plasmacytoid DC': '46.6', 'Myeloid DC': '8.5', 'NK-cell': '0.1', 'Total PBMC': '0.7', 'Vd2 gdTCR': '0.0', 'Memory CD4 T-cell Th1\\/Th17': '0.1', 'Memory CD4 T-cell Th17': '0.2', 'Memory CD4 T-cell Th2': '2.9', 'Non-Vd2 gdTCR': '0.1', 'Memory CD4 T-cell Th1': '0.3', 'Memory CD4 T-cell TFH': '0.5', 'Terminal effector memory CD4 T-cell': '0.0', 'Central memory CD8 T-cell': '4.8', 'Effector memory CD8 T-cell': '0.0', 'Terminal effector memory CD8 T-cell': '0.6', 'Non-switched memory B-cell': '0.0', 'Plasmablast': '3.3', 'Switched memory B-cell': '0.0', 'Exhausted memory B-cell': '0.7', 'Progenitor cell': '2.3', 'Memory T-reg': '1.3', 'Naive CD4 T-cell activated': '0.3', 'Naive CD8 T-cell activated': '0.6', 'Naive T-reg': '0.1'} | 1O6S, 2O72, 2OMT, 2OMU, 2OMV, 2OMX, 2OMY, 2OMZ, 3FF7, 3FF8, 3L6X, 3L6Y, 4ZT1, 4ZTE, 6CXY, 6OLE, 6OLF, 6OLG, 6VEL, 7STZ, 8H62 | {'Adipose Tissue': 1.2125261088039867, 'Adrenal Gland': 0.1914223992248062, 'Bladder': 39.2033519047619, 'Blood': 1.340954264800861, 'Blood Vessel': 0.3121561692883895, 'Brain': 0.8550442199091597, 'Breast': 38.54918344226579, 'Cervix Uteri': 23.539115789473684, 'Colon': 43.41292142490372, 'Esophagus': 53.97513367404844, 'Fallopian Tube': 14.900277777777776, 'Heart': 0.119140469221835, 'Kidney': 25.040449438202245, 'Liver': 26.60802654867257, 'Lung': 35.447986366782004, 'Muscle': 0.1378936151930261, 'Nerve': 17.518468982229404, 'Ovary': 3.6515122222222223, 'Pancreas': 56.89676829268293, 'Pituitary': 24.68741660777385, 'Prostate': 61.279967346938776, 'Salivary Gland': 92.01685185185184, 'Skin': 79.77571720232172, 'Small Intestine': 71.7519320855615, 'Spleen': 10.061029045643156, 'Stomach': 58.07813805013927, 'Testis': 0.8144204986149585, 'Thyroid': 135.176797856049, 'Uterus': 1.442593943661972, 'Vagina': 86.52345512820513} | SGO1 | MAKERCLKKSFQDSLEDIKKRMKEKRNKNLAEIGKRRSFIAAPCQIITNTSTLLKNYQDNNKMLVLALENEKSKVKEAQDIILQLRKECYYLTCQLYALKGKLTSQQTVEPAQNQEICSSGMDPNSDDSSRNLFVKDLPQIPLEETELPGQGESFQIEDQIPTIPQDTLGVDFDSGEAKSTDNVLPRTVSVRSSLKKHCNSICQFDSLDDFETSHLAGKSFEFERVGFLDPLVNMHIPENVQHNACQWSKDQVNLSPKLIQPGTFTKTKEDILESKSEQTKSKQRDTQERKREEKRKANRRKSKRMSKYKENKSENKKTVPQKKMHKSVSSNDAYNFNLEEGVHLTPFRQKVSNDSNREENNESEVSLCESSGSGDDSDDLYLPTCKYIQNPTSNSDRPVTRPLAKRALKYTDEKETEGSKPTKTPTTTPPETQQSPHLSLKDITNVSLYPVVKIRRLSLSPKKNKASPAVALPKRRCTASVNYKEPTLASKLRRGDPFTDLCFLNSPIFKQKKDLRRSKKRALEVSPAKEAIFILYYVREFVSRFPDCRKCKLETHICLR | Homo sapiens | Nucleus, Chromosome, centromere, Chromosome, centromere, kinetochore, Cytoplasm, cytoskeleton, spindle pole, Cytoplasm, cytoskeleton, microtubule organizing center, centrosome | Tissue enhanced (bone marrow, lymphoid tissue, testis) | {'Ciliated cells': '1.3', 'Basal respiratory cells': '4.6', 'Club cells': '1.9', 'Ionocytes': '2.2', 'Mucus glandular cells': '1.3', 'Serous glandular cells': '0.1', 'Gastric mucus-secreting cells': '5.3', 'Proximal enterocytes': '2.2', 'Paneth cells': '0.5', 'Distal enterocytes': '1.2', 'Intestinal goblet cells': '5.9', 'Exocrine glandular cells': '-0.306', 'Basal prostatic cells': '0.0', 'Prostatic glandular cells': '0.0', 'Breast glandular cells': '0.181', 'Breast myoepithelial cells': '0.167', 'Glandular and luminal cells': '3.0', 'Secretory cells': '0.8', 'Basal keratinocytes': '6.4', 'Suprabasal keratinocytes': '2.5', 'Basal squamous epithelial cells': '2.4', 'Squamous epithelial cells': '8.6', 'Alveolar cells type 1': '-0.232', 'Alveolar cells type 2': '-0.026', 'Salivary duct cells': '1.6', 'Ductal cells': '0.397', 'Hepatocytes': '0.360', 'Cholangiocytes': '0.0', 'Proximal tubular cells': '0.276', 'Distal tubular cells': '0.0', 'Collecting duct cells': '1.9', 'Mesothelial cells': '0.054', 'Sertoli cells': '-0.084', 'Granulosa cells': '6.3', 'Enteroendocrine cells': '0.9', 'Pancreatic endocrine cells': '3.4', 'Leydig cells': '-0.082', 'Excitatory neurons': '0.1', 'Inhibitory neurons': '0.2', 'Cone photoreceptor cells': '0.0', 'Rod photoreceptor cells': '0.3', 'Bipolar cells': '0.2', 'Horizontal cells': '1.3', 'Astrocytes': '0.0', 'Oligodendrocyte precursor cells': '1.9', 'Oligodendrocytes': '1.0', 'Microglial cells': '0.0', 'Muller glia cells': '0.1', 'Schwann cells': '0.137', 'Spermatogonia': '0.335', 'Spermatocytes': '0.737', 'Early spermatids': '0.493', 'Late spermatids': '0.041', 'Oocytes': '148.5', 'Cytotrophoblasts': '18.2', 'Syncytiotrophoblasts': '6.3', 'Extravillous trophoblasts': '47.8', 'Endothelial cells': '1.1', 'Lymphatic endothelial cells': '0.2', 'Cardiomyocytes': '0.330', 'Skeletal myocytes': '0.015', 'Smooth muscle cells': '1.2', 'Adipocytes': '0.1', 'Melanocytes': '0.431', 'Fibroblasts': '1.9', 'Peritubular cells': '-0.057', 'Endometrial stromal cells': '1.1', 'Ovarian stromal cells': '1.3', 'Undifferentiated cells': '26.5', 'T-cells': '2.9', 'B-cells': '5.1', 'Plasma cells': '12.7', 'Nk-cells': '1.8', 'Granulocytes': '1.2', 'Monocytes': '0.0', 'Macrophages': '2.9', 'Hofbauer cells': '7.4', 'Kupffer cells': '2.1', 'Dendritic cells': '12.3', 'Langerhans cells': '0.180', 'Erythroid cells': '0.061', 'Adipocytes (Subcutaneous)': '-0.060', 'Adipocytes (Visceral)': '-0.121', 'Breast glandular cells (progenitors)': '0.165', 'Adipocytes (Breast)': '-0.132', 'Colon enterocytes': '0.378', 'Colon enteroendocrine cells': '-0.031', 'Enteric glia cells': '-0.137', 'Mitotic cells (Colon)': '0.576', 'Mitotic cells (Heart)': '0.541', 'Podocytes': '-0.126', 'Ascending Loop of Henle cells': '0.343', 'Intercalated cells': '0.053', 'Cholangiocyte': '0.220', 'NK-cells (Liver)': '-0.123', 'Respiratory ciliated cells': '-0.002', 'Mitotic cells (Lung)': '0.723', 'NK-cells (Lung)': '0.040', 'B-cells (Lung)': '0.154', 'Alpha cells': '0.214', 'Beta cells': '0.126', 'Prostate glandular cells': '-0.081', 'Prostate basal glandular cells': '0.249', 'Urothelial cells': '0.282', 'Keratinocyte (other)': '0.266', 'Keratinocyte (granular)': '-0.239', 'Hair cortex cells': '0.109', 'Inner root sheath cells': '0.248', 'Outer root sheath cells': '0.283', 'Sebaceous gland cells': '0.084', 'Eccrine sweat gland cells': '0.030', 'Adipocytes (Skin)': '-0.175', 'Mitotic cells (Skin)': '0.830', 'Parietal cells': '0.259', 'Chief cells': '0.275', 'Gastric mucous cells': '0.632', 'Gastric enteroendocrine cells': '0.343', 'Mitotic cells (Stomach)': '0.828', 'Parafollicular cells': '0.000', 'Thyroid glandular cells': '-0.067', 'Mitotic cells (Thyroid)': '0.532', 'Adrenal cortex cells': '0.271', 'Adrenal medulla cells': '0.147', 'Mitotic cells (Adrenal gland)': '0.766', 'Minor salivary glandular cells': '0.147', 'Minor salivary gland ductal cells': '-0.281', 'Minor salivary gland basal cells': '0.623', 'Mitotic cells (Minor salivary gland)': '0.905', 'Adipocytes (Minor salivary gland)': '0.111', 'Somatotropes': '-0.098', 'Lactotropes': '-0.190', 'Gonadotropes': '-0.026', 'Corticotropes': '-0.183', 'Thyrotropes': '-0.086', 'Undifferentiated cells (Pituitary gland)': '0.212', 'Mitotic cells (Spleen)': '0.810', 'Platelets': '0.058', 'Erythrocytes': '0.191', 'Hematopoietic stem cells': '0.232', 'B-cells (Spleen)': '0.143', 'NK-cells (Spleen)': '-0.048', 'Amygdala excitatory': '0.1', 'Cerebellar inhibitory': '0.6', 'Cge interneuron': '0.2', 'Deep-layer corticothalamic and 6b': '0.1', 'Deep-layer intratelencephalic': '0.1', 'Deep-layer near-projecting': '0.1', 'Eccentric medium spiny neuron': '0.1', 'Hippocampal ca1-3': '0.1', 'Hippocampal ca4': '0.0', 'Hippocampal dentate gyrus': '0.2', 'Lamp5-lhx6 and chandelier': '0.2', 'Lower rhombic lip': '0.3', 'Mammillary body': '0.4', 'Medium spiny neuron': '0.1', 'Mge interneuron': '0.2', 'Midbrain-derived inhibitory': '0.2', 'Miscellaneous': '0.1', 'Splatter': '0.2', 'Thalamic excitatory': '0.2', 'Upper rhombic lip': '0.4', 'Upper-layer intratelencephalic': '0.2', 'Astrocyte': '0.5', 'Bergmann glia': '1.2', 'Central nervous system macrophage': '0.8', 'Choroid plexus epithelial cell': '0.9', 'Committed oligodendrocyte precursor': '1.9', 'Ependymal cell': '0.2', 'Oligodendrocyte': '2.3', 'Oligodendrocyte precursor cell': '3.9', 'Endothelial cell': '0.1', 'Pericyte': '0.8', 'Vascular associated smooth muscle cell': '0.2', 'Fibroblast': '0.2', 'Leukocyte': '2.4', 'Basophil': '2.7', 'Eosinophil': '1.4', 'Neutrophil': '2.6', 'Classical monocyte': '0.5', 'Non-classical monocyte': '0.6', 'Intermediate monocyte': '0.6', 'T-reg': '4.2', 'GdT-cell': '0.2', 'MAIT T-cell': '0.8', 'Memory CD4 T-cell': '0.6', 'Naive CD4 T-cell': '1.4', 'Memory CD8 T-cell': '0.7', 'Naive CD8 T-cell': '1.3', 'Memory B-cell': '8.9', 'Naive B-cell': '6.4', 'Plasmacytoid DC': '9.0', 'Myeloid DC': '1.7', 'NK-cell': '3.0', 'Total PBMC': '2.8', 'Vd2 gdTCR': '2.1', 'Memory CD4 T-cell TFH': '1.8', 'Memory CD4 T-cell Th2': '2.7', 'Memory CD4 T-cell Th17': '3.1', 'Memory CD4 T-cell Th1\\/Th17': '3.8', 'Non-Vd2 gdTCR': '1.8', 'Memory CD4 T-cell Th1': '2.2', 'Terminal effector memory CD4 T-cell': '4.0', 'Central memory CD8 T-cell': '3.7', 'Effector memory CD8 T-cell': '4.0', 'Terminal effector memory CD8 T-cell': '1.8', 'Switched memory B-cell': '7.5', 'Plasmablast': '9.1', 'Non-switched memory B-cell': '9.8', 'Exhausted memory B-cell': '11.1', 'Progenitor cell': '1.8', 'Memory T-reg': '3.7', 'Naive CD4 T-cell activated': '0.9', 'Naive CD8 T-cell activated': '0.8', 'Naive T-reg': '1.6'} | 3FGA, 3Q6S, 4A0I, 7ZJS | {'Adipose Tissue': 0.1590088970099667, 'Adrenal Gland': 0.1418290310077519, 'Bladder': 0.1539180952380952, 'Blood': 2.4452151302475778, 'Blood Vessel': 0.1042752059925093, 'Brain': 0.0466814061317183, 'Breast': 0.1450223529411764, 'Cervix Uteri': 0.2226042105263157, 'Colon': 0.4398095571245186, 'Esophagus': 0.6844072588235294, 'Fallopian Tube': 0.0458188888888888, 'Heart': 0.0530769349593495, 'Kidney': 0.1279684269662921, 'Liver': 0.1789144292035398, 'Lung': 0.4154759515570934, 'Muscle': 0.0279542627646326, 'Nerve': 0.1321255735056543, 'Ovary': 0.1790431666666666, 'Pancreas': 0.0587302652439024, 'Pituitary': 0.0848520636042402, 'Prostate': 0.1763763265306122, 'Salivary Gland': 0.3865213456790123, 'Skin': 1.6242774184632394, 'Small Intestine': 1.2551138502673798, 'Spleen': 1.2569626556016598, 'Stomach': 0.4962633760445682, 'Testis': 5.466135180055401, 'Thyroid': 0.1662916018376722, 'Uterus': 0.1016457746478873, 'Vagina': 0.7459582051282051} | [39.93, 46.46, 52.9, 44.21, 41.4, 39.93, 35.91, 38.61, 36.44, 36.25, 34.86, 32.82, 32.01, 32.75, 31.69, 35.64, 36.35, 34.66, 33.32, 32.71, 35.01, 30.17, 37.05, 36.53, 48.19, 58.22, 64.94, 73.22, 78.33, 82.63, 85.79, 89.39, 87.89, 85.58, 83.93, 89.1, 89.27, 90.66, 87.86, 86.2, 82.97, 72.75, 73.3, 76.44, 82.38, 82.41, 79.49, 86.6, 76.32, 85.48, 88.69, 84.35, 87.75, 90.57, 88.72, 89.46, 87.48, 85.3, 81.72, 79.46, 77.26, 69.01, 67.1, 62.83, 67.71, 74.96, 82.95, 86.74, 86.35, 86.49, 84.6, 85.99, 85.64, 87.19, 89.23, 89.3, 90.62, 84.21, 85.42, 83.34, 84.28, 89.8, 89.78, 87.53, 87.64, 85.98, 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0.58, 0.42, 0.58, 0.62, 0.5, 0.49, 0.53, 0.5, 0.49, 0.66, 0.59, 0.43, 0.57, 0.71, 0.67, 0.55, 0.41, 0.42, 0.38, 0.64, 0.68, 0.49, 0.54, 0.62, 0.39, 0.61, 0.65, 0.47, 0.54, 0.72, 0.79, 0.81, 0.81, 0.69, 0.96, 0.92, 0.91, 0.86, 0.98, 1.0, 0.92, 0.97, 0.84, 0.94, 0.92, 1.0, 0.97, 1.0, 0.99, 0.99, 1.0, 0.97, 1.0, 0.98, 1.0, 0.83, 1.0, 0.89, 0.98, 1.0, 0.97, 0.85, 0.85, 0.82, 0.91, 0.85, 0.92, 0.87, 0.93, 0.87, 1.0, 0.97, 0.99, 0.98, 0.99, 1.0, 0.96, 0.94, 0.98, 0.97, 0.99, 0.96, 0.99, 0.96, 0.99, 0.96, 0.99, 0.97, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 0.99, 0.97, 1.0, 0.95, 1.0, 0.99, 0.97, 0.96, 0.95, 0.95, 0.93, 0.8, 0.97, 0.83, 0.89, 0.79, 0.85, 0.85, 0.77, 0.76, 0.83, 0.97, 0.82, 0.8, 0.81, 0.76, 0.82, 0.85, 0.81, 0.76, 0.89, 0.81, 0.86, 0.91, 0.72, 0.94, 0.75, 0.96, 0.76, 0.95, 0.89, 0.99, 1.0, 0.98, 0.87, 0.92, 0.91, 0.89, 0.91, 0.83, 0.97, 0.84, 0.85, 0.99, 0.9, 0.93, 0.91, 0.92, 0.96, 0.82, 0.95, 0.81, 0.87, 0.93, 0.94, 0.94, 0.99, 0.92, 0.96, 0.91, 0.85, 0.68, 0.9, 0.84, 0.86, 0.97, 0.94, 0.92, 0.98, 0.98, 0.9, 0.94, 0.93, 0.9, 0.81, 0.89, 0.71, 0.94, 0.63, 0.93, 0.92, 0.93, 0.98, 0.93, 1.0, 0.94, 1.0, 0.97, 0.98, 0.89, 0.96, 0.91, 0.95, 1.0, 1.0, 0.97, 1.0, 0.94, 1.0, 1.0, 1.0, 0.97, 0.99, 0.9, 0.86, 0.97, 0.94, 0.85, 0.82, 0.94, 0.91, 0.88, 0.92, 0.9, 0.93, 0.97, 0.99, 1.0, 1.0, 1.0, 1.0, 1.0, 0.97, 1.0, 0.99, 1.0, 0.75, 1.0, 0.83, 1.0, 1.0, 1.0, 1.0, 1.0, 0.98, 0.95, 0.97, 0.97, 1.0, 0.99, 1.0, 1.0, 0.9, 0.97, 0.72, 0.86, 0.92, 0.91, 0.75, 0.97, 0.69, 0.62, 0.77, 0.86, 0.81, 0.95, 0.88, 0.65, 0.73, 0.87, 0.84, 0.67, 0.88, 0.94, 0.82, 0.9, 0.85, 0.9, 0.9, 0.96, 0.99, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 0.94, 1.0, 1.0, 0.94, 0.85, 0.93, 0.85, 0.89, 0.86, 0.89, 0.68, 0.94, 1.0, 1.0, 0.95, 1.0, 0.92, 1.0, 0.99, 1.0, 1.0, 1.0, 1.0, 1.0, 0.95, 0.99, 0.96, 0.93, 0.98, 0.93, 1.0, 0.97, 0.99, 1.0, 0.93, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 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Forms a ternary complex composed of ADAM10, CADH1 and EPHA4, | null | null | KLRG1, SPEF1, DLGAP5, AJAP1, RAPGEF2, RAB8B, PIP5K1C, PKP2, TRPV4, CTNNB1, CAV1, DDR1, TBC1D2, CTNNA1, JUP, CTNND1, PSEN1, LIMA1, CDH1, JUP, ADAM10, CADH1 , EPHA4, | null | null | null | null | Homodimer | null | 79.91949 | 0.474025 | 54.806613 | 0.821729 | 1,381 |
P12830 | Q6UVJ0 | null | degron_data | CDH1 | MGPWSRSLSALLLLLQVSSWLCQEPEPCHPGFDAESYTFTVPRRHLERGRVLGRVNFEDCTGRQRTAYFSLDTRFKVGTDGVITVKRPLRFHNPQIHFLVYAWDSTYRKFSTKVTLNTVGHHHRPPPHQASVSGIQAELLTFPNSSPGLRRQKRDWVIPPISCPENEKGPFPKNLVQIKSNKDKEGKVFYSITGQGADTPPVGVFIIERETGWLKVTEPLDRERIATYTLFSHAVSSNGNAVEDPMEILITVTDQNDNKPEFTQEVFKGSVMEGALPGTSVMEVTATDADDDVNTYNAAIAYTILSQDPELPDKNMFTINRNTGVISVVTTGLDRESFPTYTLVVQAADLQGEGLSTTATAVITVTDTNDNPPIFNPTTYKGQVPENEANVVITTLKVTDADAPNTPAWEAVYTILNDDGGQFVVTTNPVNNDGILKTAKGLDFEAKQQYILHVAVTNVVPFEVSLTTSTATVTVDVLDVNEAPIFVPPEKRVEVSEDFGVGQEITSYTAQEPDTFMEQKITYRIWRDTANWLEINPDTGAISTRAELDREDFEHVKNSTYTALIIATDNGSPVATGTGTLLLILSDVNDNAPIPEPRTIFFCERNPKPQVINIIDADLPPNTSPFTAELTHGASANWTIQYNDPTQESIILKPKMALEVGDYKINLKLMDNQNKDQVTTLEVSVCDCEGAAGVCRKAQPVEAGLQIPAILGILGGILALLILILLLLLFLRRRAVVKEPLLPPEDDTRDNVYYYDEEGGGEEDQDFDLSQLHRGLDARPEVTRNDVAPTLMSVPRYLPRPANPDEIGNFIDENLKAADTDPTAPPYDSLLVFDYEGSGSEAASLSSLNSSESDKDQDYDYLNEWGNRFKKLADMYGGGEDD | Homo sapiens | Cell junction, adherens junction, Cell membrane, Endosome, Golgi apparatus, trans-Golgi network, Cytoplasm, Cell junction, desmosome | Tissue enhanced (parathyroid) | {'Ciliated cells': '119.1', 'Basal respiratory cells': '71.1', 'Club cells': '97.3', 'Ionocytes': '81.0', 'Mucus glandular cells': '155.0', 'Serous glandular cells': '67.8', 'Gastric mucus-secreting cells': '133.2', 'Proximal enterocytes': '140.9', 'Paneth cells': '125.1', 'Distal enterocytes': '307.5', 'Intestinal goblet cells': '173.5', 'Exocrine glandular cells': '-0.605', 'Basal prostatic cells': '68.3', 'Prostatic glandular cells': '186.7', 'Breast glandular cells': '0.773', 'Breast myoepithelial cells': '0.700', 'Glandular and luminal cells': '313.0', 'Secretory cells': '82.3', 'Basal keratinocytes': '102.5', 'Suprabasal keratinocytes': '162.6', 'Basal squamous epithelial cells': '51.0', 'Squamous epithelial cells': '106.9', 'Alveolar cells type 1': '0.437', 'Alveolar cells type 2': '0.706', 'Salivary duct cells': '95.9', 'Ductal cells': '0.541', 'Hepatocytes': '0.600', 'Cholangiocytes': '129.7', 'Proximal tubular cells': '0.042', 'Distal tubular cells': '0.0', 'Collecting duct cells': '143.9', 'Mesothelial cells': '0.799', 'Sertoli cells': '0.252', 'Granulosa cells': '12.9', 'Enteroendocrine cells': '92.4', 'Pancreatic endocrine cells': '78.1', 'Leydig cells': '0.264', 'Excitatory neurons': '0.7', 'Inhibitory neurons': '1.3', 'Cone photoreceptor cells': '0.0', 'Rod photoreceptor cells': '0.0', 'Bipolar cells': '0.2', 'Horizontal cells': '0.6', 'Astrocytes': '0.6', 'Oligodendrocyte precursor cells': '0.5', 'Oligodendrocytes': '29.9', 'Microglial cells': '0.9', 'Muller glia cells': '0.1', 'Schwann cells': '0.131', 'Spermatogonia': '0.392', 'Spermatocytes': '0.193', 'Early spermatids': '-0.217', 'Late spermatids': '-0.290', 'Oocytes': '16.9', 'Cytotrophoblasts': '119.2', 'Syncytiotrophoblasts': '45.0', 'Extravillous trophoblasts': '24.9', 'Endothelial cells': '6.1', 'Lymphatic endothelial cells': '0.4', 'Cardiomyocytes': '0.135', 'Skeletal myocytes': '0.107', 'Smooth muscle cells': '5.8', 'Adipocytes': '2.1', 'Melanocytes': '0.335', 'Fibroblasts': '6.5', 'Peritubular cells': '0.210', 'Endometrial stromal cells': '27.7', 'Ovarian stromal cells': '0.7', 'Undifferentiated cells': '101.6', 'T-cells': '2.9', 'B-cells': '4.4', 'Plasma cells': '6.1', 'Nk-cells': '0.0', 'Granulocytes': '8.4', 'Monocytes': '0.0', 'Macrophages': '6.0', 'Hofbauer cells': '4.3', 'Kupffer cells': '1.0', 'Dendritic cells': '5.9', 'Langerhans cells': '0.304', 'Erythroid cells': '0.036', 'Adipocytes (Subcutaneous)': '-0.081', 'Adipocytes (Visceral)': '-0.209', 'Breast glandular cells (progenitors)': '0.538', 'Adipocytes (Breast)': '-0.689', 'Colon enterocytes': '0.790', 'Colon enteroendocrine cells': '0.112', 'Enteric glia cells': '-0.048', 'Mitotic cells (Colon)': '0.299', 'Mitotic cells (Heart)': '0.120', 'Podocytes': '-0.118', 'Ascending Loop of Henle cells': '0.475', 'Intercalated cells': '0.212', 'Cholangiocyte': '0.090', 'NK-cells (Liver)': '-0.005', 'Respiratory ciliated cells': '-0.012', 'Mitotic cells (Lung)': '0.071', 'NK-cells (Lung)': '-0.266', 'B-cells (Lung)': '-0.296', 'Alpha cells': '0.270', 'Beta cells': '0.152', 'Prostate glandular cells': '0.764', 'Prostate basal glandular cells': '0.540', 'Urothelial cells': '0.205', 'Keratinocyte (other)': '0.510', 'Keratinocyte (granular)': '0.055', 'Hair cortex cells': '0.080', 'Inner root sheath cells': '0.131', 'Outer root sheath cells': '0.175', 'Sebaceous gland cells': '0.156', 'Eccrine sweat gland cells': '-0.207', 'Adipocytes (Skin)': '-0.244', 'Mitotic cells (Skin)': '0.442', 'Parietal cells': '0.654', 'Chief cells': '0.649', 'Gastric mucous cells': '0.781', 'Gastric enteroendocrine cells': '0.590', 'Mitotic cells (Stomach)': '0.445', 'Parafollicular cells': '0.173', 'Thyroid glandular cells': '0.865', 'Mitotic cells (Thyroid)': '-0.081', 'Adrenal cortex cells': '0.051', 'Adrenal medulla cells': '0.087', 'Mitotic cells (Adrenal gland)': '0.072', 'Minor salivary glandular cells': '0.371', 'Minor salivary gland ductal cells': '-0.142', 'Minor salivary gland basal cells': '0.582', 'Mitotic cells (Minor salivary gland)': '0.567', 'Adipocytes (Minor salivary gland)': '0.050', 'Somatotropes': '0.121', 'Lactotropes': '0.322', 'Gonadotropes': '0.330', 'Corticotropes': '0.180', 'Thyrotropes': '0.496', 'Undifferentiated cells (Pituitary gland)': '-0.108', 'Mitotic cells (Spleen)': '-0.228', 'Platelets': '-0.050', 'Erythrocytes': '-0.158', 'Hematopoietic stem cells': '-0.211', 'B-cells (Spleen)': '0.266', 'NK-cells (Spleen)': '0.309', 'Amygdala excitatory': '1.0', 'Cerebellar inhibitory': '0.9', 'Cge interneuron': '0.7', 'Deep-layer corticothalamic and 6b': '1.5', 'Deep-layer intratelencephalic': '0.7', 'Deep-layer near-projecting': '0.7', 'Eccentric medium spiny neuron': '0.6', 'Hippocampal ca1-3': '1.9', 'Hippocampal ca4': '1.2', 'Hippocampal dentate gyrus': '1.1', 'Lamp5-lhx6 and chandelier': '0.5', 'Lower rhombic lip': '0.8', 'Mammillary body': '0.6', 'Medium spiny neuron': '0.7', 'Mge interneuron': '1.7', 'Midbrain-derived inhibitory': '0.7', 'Miscellaneous': '0.9', 'Splatter': '3.8', 'Thalamic excitatory': '0.5', 'Upper rhombic lip': '0.8', 'Upper-layer intratelencephalic': '0.6', 'Astrocyte': '4.4', 'Bergmann glia': '0.2', 'Central nervous system macrophage': '0.6', 'Choroid plexus epithelial cell': '52.1', 'Committed oligodendrocyte precursor': '41.5', 'Ependymal cell': '4.8', 'Oligodendrocyte': '53.1', 'Oligodendrocyte precursor cell': '2.4', 'Endothelial cell': '0.7', 'Pericyte': '0.3', 'Vascular associated smooth muscle cell': '0.0', 'Fibroblast': '17.4', 'Leukocyte': '1.1', 'Basophil': '0.0', 'Eosinophil': '0.0', 'Neutrophil': '0.0', 'Classical monocyte': '0.0', 'Non-classical monocyte': '0.0', 'Intermediate monocyte': '0.0', 'T-reg': '2.3', 'GdT-cell': '0.0', 'MAIT T-cell': '0.0', 'Memory CD4 T-cell': '0.0', 'Naive CD4 T-cell': '0.1', 'Memory CD8 T-cell': '0.2', 'Naive CD8 T-cell': '0.3', 'Memory B-cell': '0.0', 'Naive B-cell': '0.1', 'Plasmacytoid DC': '46.6', 'Myeloid DC': '8.5', 'NK-cell': '0.1', 'Total PBMC': '0.7', 'Vd2 gdTCR': '0.0', 'Memory CD4 T-cell Th1\\/Th17': '0.1', 'Memory CD4 T-cell Th17': '0.2', 'Memory CD4 T-cell Th2': '2.9', 'Non-Vd2 gdTCR': '0.1', 'Memory CD4 T-cell Th1': '0.3', 'Memory CD4 T-cell TFH': '0.5', 'Terminal effector memory CD4 T-cell': '0.0', 'Central memory CD8 T-cell': '4.8', 'Effector memory CD8 T-cell': '0.0', 'Terminal effector memory CD8 T-cell': '0.6', 'Non-switched memory B-cell': '0.0', 'Plasmablast': '3.3', 'Switched memory B-cell': '0.0', 'Exhausted memory B-cell': '0.7', 'Progenitor cell': '2.3', 'Memory T-reg': '1.3', 'Naive CD4 T-cell activated': '0.3', 'Naive CD8 T-cell activated': '0.6', 'Naive T-reg': '0.1'} | 1O6S, 2O72, 2OMT, 2OMU, 2OMV, 2OMX, 2OMY, 2OMZ, 3FF7, 3FF8, 3L6X, 3L6Y, 4ZT1, 4ZTE, 6CXY, 6OLE, 6OLF, 6OLG, 6VEL, 7STZ, 8H62 | {'Adipose Tissue': 1.2125261088039867, 'Adrenal Gland': 0.1914223992248062, 'Bladder': 39.2033519047619, 'Blood': 1.340954264800861, 'Blood Vessel': 0.3121561692883895, 'Brain': 0.8550442199091597, 'Breast': 38.54918344226579, 'Cervix Uteri': 23.539115789473684, 'Colon': 43.41292142490372, 'Esophagus': 53.97513367404844, 'Fallopian Tube': 14.900277777777776, 'Heart': 0.119140469221835, 'Kidney': 25.040449438202245, 'Liver': 26.60802654867257, 'Lung': 35.447986366782004, 'Muscle': 0.1378936151930261, 'Nerve': 17.518468982229404, 'Ovary': 3.6515122222222223, 'Pancreas': 56.89676829268293, 'Pituitary': 24.68741660777385, 'Prostate': 61.279967346938776, 'Salivary Gland': 92.01685185185184, 'Skin': 79.77571720232172, 'Small Intestine': 71.7519320855615, 'Spleen': 10.061029045643156, 'Stomach': 58.07813805013927, 'Testis': 0.8144204986149585, 'Thyroid': 135.176797856049, 'Uterus': 1.442593943661972, 'Vagina': 86.52345512820513} | SASS6 | MSQVLFHQLVPLQVKCKDCEERRVSIRMSIELQSVSNPVHRKDLVIRLTDDTDPFFLYNLVISEEDFQSLKFQQGLLVDFLAFPQKFIDLLQQCTQEHAKEIPRFLLQLVSPAAILDNSPAFLNVVETNPFKHLTHLSLKLLPGNDVEIKKFLAGCLKCSKEEKLSLMQSLDDATKQLDFTRKTLAEKKQELDKLRNEWASHTAALTNKHSQELTNEKEKALQAQVQYQQQHEQQKKDLEILHQQNIHQLQNRLSELEAANKDLTERKYKGDSTIRELKAKLSGVEEELQRTKQEVLSLRRENSTLDVECHEKEKHVNQLQTKVAVLEQEIKDKDQLVLRTKEAFDTIQEQKVVLEENGEKNQVQLGKLEATIKSLSAELLKANEIIKKLQGDLKTLMGKLKLKNTVTIQQEKLLAEKEEKLQKEQKELQDVGQSLRIKEQEVCKLQEQLEATVKKLEESKQLLKNNEKLITWLNKELNENQLVRKQDVLGPSTTPPAHSSSNTIRSGISPNLNVVDGRLTYPTCGIGYPVSSAFAFQNTFPHSISAKNTSHPGSGTKVQFNLQFTKPNASLGDVQSGATISMPCSTDKENGENVGLESKYLKKREDSIPLRGLSQNLFSNSDHQRDGTLGALHTSSKPTALPSASSAYFPGQLPNS | Homo sapiens | Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriole | Low tissue specificity | {'Ciliated cells': '6.1', 'Basal respiratory cells': '6.5', 'Club cells': '5.8', 'Ionocytes': '4.0', 'Mucus glandular cells': '5.3', 'Serous glandular cells': '3.9', 'Gastric mucus-secreting cells': '7.1', 'Proximal enterocytes': '2.4', 'Paneth cells': '1.8', 'Distal enterocytes': '1.7', 'Intestinal goblet cells': '6.1', 'Exocrine glandular cells': '-0.518', 'Basal prostatic cells': '6.6', 'Prostatic glandular cells': '9.2', 'Breast glandular cells': '0.599', 'Breast myoepithelial cells': '0.567', 'Glandular and luminal cells': '5.6', 'Secretory cells': '6.7', 'Basal keratinocytes': '7.5', 'Suprabasal keratinocytes': '5.8', 'Basal squamous epithelial cells': '6.9', 'Squamous epithelial cells': '12.1', 'Alveolar cells type 1': '-0.095', 'Alveolar cells type 2': '-0.084', 'Salivary duct cells': '8.3', 'Ductal cells': '0.463', 'Hepatocytes': '0.168', 'Cholangiocytes': '9.5', 'Proximal tubular cells': '0.018', 'Distal tubular cells': '3.1', 'Collecting duct cells': '1.9', 'Mesothelial cells': '0.325', 'Sertoli cells': '0.112', 'Granulosa cells': '12.1', 'Enteroendocrine cells': '7.3', 'Pancreatic endocrine cells': '1.7', 'Leydig cells': '0.014', 'Excitatory neurons': '7.3', 'Inhibitory neurons': '9.2', 'Cone photoreceptor cells': '15.3', 'Rod photoreceptor cells': '19.9', 'Bipolar cells': '17.3', 'Horizontal cells': '7.6', 'Astrocytes': '8.1', 'Oligodendrocyte precursor cells': '4.7', 'Oligodendrocytes': '15.0', 'Microglial cells': '5.4', 'Muller glia cells': '10.8', 'Schwann cells': '0.091', 'Spermatogonia': '0.365', 'Spermatocytes': '0.704', 'Early spermatids': '0.421', 'Late spermatids': '-0.100', 'Oocytes': '171.3', 'Cytotrophoblasts': '14.6', 'Syncytiotrophoblasts': '6.1', 'Extravillous trophoblasts': '17.8', 'Endothelial cells': '6.5', 'Lymphatic endothelial cells': '5.2', 'Cardiomyocytes': '0.529', 'Skeletal myocytes': '-0.120', 'Smooth muscle cells': '5.7', 'Adipocytes': '6.5', 'Melanocytes': '0.062', 'Fibroblasts': '7.3', 'Peritubular cells': '0.055', 'Endometrial stromal cells': '5.5', 'Ovarian stromal cells': '10.0', 'Undifferentiated cells': '18.0', 'T-cells': '8.4', 'B-cells': '9.8', 'Plasma cells': '19.6', 'Nk-cells': '14.8', 'Granulocytes': '7.6', 'Monocytes': '3.9', 'Macrophages': '5.3', 'Hofbauer cells': '7.2', 'Kupffer cells': '5.6', 'Dendritic cells': '7.4', 'Langerhans cells': '0.128', 'Erythroid cells': '0.056', 'Adipocytes (Subcutaneous)': '-0.273', 'Adipocytes (Visceral)': '-0.352', 'Breast glandular cells (progenitors)': '0.429', 'Adipocytes (Breast)': '-0.603', 'Colon enterocytes': '-0.025', 'Colon enteroendocrine cells': '0.243', 'Enteric glia cells': '0.186', 'Mitotic cells (Colon)': '-0.066', 'Mitotic cells (Heart)': '0.472', 'Podocytes': '-0.071', 'Ascending Loop of Henle cells': '0.475', 'Intercalated cells': '-0.049', 'Cholangiocyte': '0.282', 'NK-cells (Liver)': '-0.160', 'Respiratory ciliated cells': '0.105', 'Mitotic cells (Lung)': '0.255', 'NK-cells (Lung)': '0.040', 'B-cells (Lung)': '-0.004', 'Alpha cells': '0.383', 'Beta cells': '0.236', 'Prostate glandular cells': '-0.089', 'Prostate basal glandular cells': '0.231', 'Urothelial cells': '0.158', 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0.67, 0.58, 0.66, 0.67, 0.65, 0.5, 0.73, 0.86, 0.64, 0.79, 0.92, 0.84, 0.96, 1.0, 1.0, 1.0, 1.0, 1.0, 0.87, 0.98, 0.77, 0.96, 1.0, 0.97, 1.0, 0.99, 1.0, 0.97, 0.98, 0.82, 0.98, 0.85, 0.99, 0.93, 1.0, 0.99, 0.98, 0.98, 0.97, 0.98, 0.92, 0.99, 0.88, 1.0, 0.89, 0.99, 0.82, 0.98, 0.99, 0.93, 0.92, 0.91, 0.81, 0.85, 0.99, 0.87, 0.98, 1.0, 0.99, 1.0, 1.0, 0.99, 0.99, 0.99, 0.99, 1.0, 0.95, 1.0, 0.94, 0.96, 1.0, 0.94, 0.87, 1.0, 0.85, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 0.93, 0.99, 0.98, 0.97, 0.98, 0.9, 0.97, 0.91, 0.99, 1.0, 1.0, 0.93, 1.0, 0.9, 1.0, 1.0, 0.9, 0.95, 0.86, 0.91, 0.99, 0.96, 1.0, 1.0, 1.0, 0.99, 0.98, 0.98, 0.98, 1.0, 0.89, 0.99, 0.84, 0.98, 0.99, 0.98, 0.92, 0.98, 0.96, 0.98, 1.0, 1.0, 0.99, 0.99, 1.0, 0.99, 0.96, 0.98, 0.69, 0.77, 0.76, 0.94, 0.85, 0.88, 0.86, 0.91, 0.85, 0.88, 0.91, 0.92, 0.94, 0.91, 0.97, 0.92, 1.0, 0.95, 0.99, 1.0, 0.92, 1.0, 0.88, 1.0, 1.0, 0.98, 1.0, 0.97, 0.99, 1.0, 0.98, 0.99, 1.0, 0.94, 0.9, 0.97, 0.94, 1.0, 1.0, 0.99, 0.95, 0.98, 0.93, 0.94, 0.98, 1.0, 1.0, 1.0, 1.0, 0.99, 0.93, 0.98, 0.98, 0.97, 0.96, 0.94, 0.93, 0.87, 0.92, 0.95] | null | Component of an E-cadherin/ catenin adhesion complex composed of at least E-cadherin/CDH1, beta-catenin/CTNNB1 or gamma-catenin/JUP, and potentially alpha-catenin/CTNNA1. Forms a ternary complex composed of ADAM10, CADH1 and EPHA4, | null | null | KLRG1, SPEF1, DLGAP5, AJAP1, RAPGEF2, RAB8B, PIP5K1C, PKP2, TRPV4, CTNNB1, CAV1, DDR1, TBC1D2, CTNNA1, JUP, CTNND1, PSEN1, LIMA1, CDH1, JUP, ADAM10, CADH1 , EPHA4, | null | null | null | null | Homodimer | null | 79.91949 | 0.474025 | 73.293166 | 0.627275 | 1,115 |
P12830 | Q86T82 | null | degron_data | CDH1 | MGPWSRSLSALLLLLQVSSWLCQEPEPCHPGFDAESYTFTVPRRHLERGRVLGRVNFEDCTGRQRTAYFSLDTRFKVGTDGVITVKRPLRFHNPQIHFLVYAWDSTYRKFSTKVTLNTVGHHHRPPPHQASVSGIQAELLTFPNSSPGLRRQKRDWVIPPISCPENEKGPFPKNLVQIKSNKDKEGKVFYSITGQGADTPPVGVFIIERETGWLKVTEPLDRERIATYTLFSHAVSSNGNAVEDPMEILITVTDQNDNKPEFTQEVFKGSVMEGALPGTSVMEVTATDADDDVNTYNAAIAYTILSQDPELPDKNMFTINRNTGVISVVTTGLDRESFPTYTLVVQAADLQGEGLSTTATAVITVTDTNDNPPIFNPTTYKGQVPENEANVVITTLKVTDADAPNTPAWEAVYTILNDDGGQFVVTTNPVNNDGILKTAKGLDFEAKQQYILHVAVTNVVPFEVSLTTSTATVTVDVLDVNEAPIFVPPEKRVEVSEDFGVGQEITSYTAQEPDTFMEQKITYRIWRDTANWLEINPDTGAISTRAELDREDFEHVKNSTYTALIIATDNGSPVATGTGTLLLILSDVNDNAPIPEPRTIFFCERNPKPQVINIIDADLPPNTSPFTAELTHGASANWTIQYNDPTQESIILKPKMALEVGDYKINLKLMDNQNKDQVTTLEVSVCDCEGAAGVCRKAQPVEAGLQIPAILGILGGILALLILILLLLLFLRRRAVVKEPLLPPEDDTRDNVYYYDEEGGGEEDQDFDLSQLHRGLDARPEVTRNDVAPTLMSVPRYLPRPANPDEIGNFIDENLKAADTDPTAPPYDSLLVFDYEGSGSEAASLSSLNSSESDKDQDYDYLNEWGNRFKKLADMYGGGEDD | Homo sapiens | Cell junction, adherens junction, Cell membrane, Endosome, Golgi apparatus, trans-Golgi network, Cytoplasm, Cell junction, desmosome | Tissue enhanced (parathyroid) | {'Ciliated cells': '119.1', 'Basal respiratory cells': '71.1', 'Club cells': '97.3', 'Ionocytes': '81.0', 'Mucus glandular cells': '155.0', 'Serous glandular cells': '67.8', 'Gastric mucus-secreting cells': '133.2', 'Proximal enterocytes': '140.9', 'Paneth cells': '125.1', 'Distal enterocytes': '307.5', 'Intestinal goblet cells': '173.5', 'Exocrine glandular cells': '-0.605', 'Basal prostatic cells': '68.3', 'Prostatic glandular cells': '186.7', 'Breast glandular cells': '0.773', 'Breast myoepithelial cells': '0.700', 'Glandular and luminal cells': '313.0', 'Secretory cells': '82.3', 'Basal keratinocytes': '102.5', 'Suprabasal keratinocytes': '162.6', 'Basal squamous epithelial cells': '51.0', 'Squamous epithelial cells': '106.9', 'Alveolar cells type 1': '0.437', 'Alveolar cells type 2': '0.706', 'Salivary duct cells': '95.9', 'Ductal cells': '0.541', 'Hepatocytes': '0.600', 'Cholangiocytes': '129.7', 'Proximal tubular cells': '0.042', 'Distal tubular cells': '0.0', 'Collecting duct cells': '143.9', 'Mesothelial cells': '0.799', 'Sertoli cells': '0.252', 'Granulosa cells': '12.9', 'Enteroendocrine cells': '92.4', 'Pancreatic endocrine cells': '78.1', 'Leydig cells': '0.264', 'Excitatory neurons': '0.7', 'Inhibitory neurons': '1.3', 'Cone photoreceptor cells': '0.0', 'Rod photoreceptor cells': '0.0', 'Bipolar cells': '0.2', 'Horizontal cells': '0.6', 'Astrocytes': '0.6', 'Oligodendrocyte precursor cells': '0.5', 'Oligodendrocytes': '29.9', 'Microglial cells': '0.9', 'Muller glia cells': '0.1', 'Schwann cells': '0.131', 'Spermatogonia': '0.392', 'Spermatocytes': '0.193', 'Early spermatids': '-0.217', 'Late spermatids': '-0.290', 'Oocytes': '16.9', 'Cytotrophoblasts': '119.2', 'Syncytiotrophoblasts': '45.0', 'Extravillous trophoblasts': '24.9', 'Endothelial cells': '6.1', 'Lymphatic endothelial cells': '0.4', 'Cardiomyocytes': '0.135', 'Skeletal myocytes': '0.107', 'Smooth muscle cells': '5.8', 'Adipocytes': '2.1', 'Melanocytes': '0.335', 'Fibroblasts': '6.5', 'Peritubular cells': '0.210', 'Endometrial stromal cells': '27.7', 'Ovarian stromal cells': '0.7', 'Undifferentiated cells': '101.6', 'T-cells': '2.9', 'B-cells': '4.4', 'Plasma cells': '6.1', 'Nk-cells': '0.0', 'Granulocytes': '8.4', 'Monocytes': '0.0', 'Macrophages': '6.0', 'Hofbauer cells': '4.3', 'Kupffer cells': '1.0', 'Dendritic cells': '5.9', 'Langerhans cells': '0.304', 'Erythroid cells': '0.036', 'Adipocytes (Subcutaneous)': '-0.081', 'Adipocytes (Visceral)': '-0.209', 'Breast glandular cells (progenitors)': '0.538', 'Adipocytes (Breast)': '-0.689', 'Colon enterocytes': '0.790', 'Colon enteroendocrine cells': '0.112', 'Enteric glia cells': '-0.048', 'Mitotic cells (Colon)': '0.299', 'Mitotic cells (Heart)': '0.120', 'Podocytes': '-0.118', 'Ascending Loop of Henle cells': '0.475', 'Intercalated cells': '0.212', 'Cholangiocyte': '0.090', 'NK-cells (Liver)': '-0.005', 'Respiratory ciliated cells': '-0.012', 'Mitotic cells (Lung)': '0.071', 'NK-cells (Lung)': '-0.266', 'B-cells (Lung)': '-0.296', 'Alpha cells': '0.270', 'Beta cells': '0.152', 'Prostate glandular cells': '0.764', 'Prostate basal glandular cells': '0.540', 'Urothelial cells': '0.205', 'Keratinocyte (other)': '0.510', 'Keratinocyte (granular)': '0.055', 'Hair cortex cells': '0.080', 'Inner root sheath cells': '0.131', 'Outer root sheath cells': '0.175', 'Sebaceous gland cells': '0.156', 'Eccrine sweat gland cells': '-0.207', 'Adipocytes (Skin)': '-0.244', 'Mitotic cells (Skin)': '0.442', 'Parietal cells': '0.654', 'Chief cells': '0.649', 'Gastric mucous cells': '0.781', 'Gastric enteroendocrine cells': '0.590', 'Mitotic cells (Stomach)': '0.445', 'Parafollicular cells': '0.173', 'Thyroid glandular cells': '0.865', 'Mitotic cells (Thyroid)': '-0.081', 'Adrenal cortex cells': '0.051', 'Adrenal medulla cells': '0.087', 'Mitotic cells (Adrenal gland)': '0.072', 'Minor salivary glandular cells': '0.371', 'Minor salivary gland ductal cells': '-0.142', 'Minor salivary gland basal cells': '0.582', 'Mitotic cells (Minor salivary gland)': '0.567', 'Adipocytes (Minor salivary gland)': '0.050', 'Somatotropes': '0.121', 'Lactotropes': '0.322', 'Gonadotropes': '0.330', 'Corticotropes': '0.180', 'Thyrotropes': '0.496', 'Undifferentiated cells (Pituitary gland)': '-0.108', 'Mitotic cells (Spleen)': '-0.228', 'Platelets': '-0.050', 'Erythrocytes': '-0.158', 'Hematopoietic stem cells': '-0.211', 'B-cells (Spleen)': '0.266', 'NK-cells (Spleen)': '0.309', 'Amygdala excitatory': '1.0', 'Cerebellar inhibitory': '0.9', 'Cge interneuron': '0.7', 'Deep-layer corticothalamic and 6b': '1.5', 'Deep-layer intratelencephalic': '0.7', 'Deep-layer near-projecting': '0.7', 'Eccentric medium spiny neuron': '0.6', 'Hippocampal ca1-3': '1.9', 'Hippocampal ca4': '1.2', 'Hippocampal dentate gyrus': '1.1', 'Lamp5-lhx6 and chandelier': '0.5', 'Lower rhombic lip': '0.8', 'Mammillary body': '0.6', 'Medium spiny neuron': '0.7', 'Mge interneuron': '1.7', 'Midbrain-derived inhibitory': '0.7', 'Miscellaneous': '0.9', 'Splatter': '3.8', 'Thalamic excitatory': '0.5', 'Upper rhombic lip': '0.8', 'Upper-layer intratelencephalic': '0.6', 'Astrocyte': '4.4', 'Bergmann glia': '0.2', 'Central nervous system macrophage': '0.6', 'Choroid plexus epithelial cell': '52.1', 'Committed oligodendrocyte precursor': '41.5', 'Ependymal cell': '4.8', 'Oligodendrocyte': '53.1', 'Oligodendrocyte precursor cell': '2.4', 'Endothelial cell': '0.7', 'Pericyte': '0.3', 'Vascular associated smooth muscle cell': '0.0', 'Fibroblast': '17.4', 'Leukocyte': '1.1', 'Basophil': '0.0', 'Eosinophil': '0.0', 'Neutrophil': '0.0', 'Classical monocyte': '0.0', 'Non-classical monocyte': '0.0', 'Intermediate monocyte': '0.0', 'T-reg': '2.3', 'GdT-cell': '0.0', 'MAIT T-cell': '0.0', 'Memory CD4 T-cell': '0.0', 'Naive CD4 T-cell': '0.1', 'Memory CD8 T-cell': '0.2', 'Naive CD8 T-cell': '0.3', 'Memory B-cell': '0.0', 'Naive B-cell': '0.1', 'Plasmacytoid DC': '46.6', 'Myeloid DC': '8.5', 'NK-cell': '0.1', 'Total PBMC': '0.7', 'Vd2 gdTCR': '0.0', 'Memory CD4 T-cell Th1\\/Th17': '0.1', 'Memory CD4 T-cell Th17': '0.2', 'Memory CD4 T-cell Th2': '2.9', 'Non-Vd2 gdTCR': '0.1', 'Memory CD4 T-cell Th1': '0.3', 'Memory CD4 T-cell TFH': '0.5', 'Terminal effector memory CD4 T-cell': '0.0', 'Central memory CD8 T-cell': '4.8', 'Effector memory CD8 T-cell': '0.0', 'Terminal effector memory CD8 T-cell': '0.6', 'Non-switched memory B-cell': '0.0', 'Plasmablast': '3.3', 'Switched memory B-cell': '0.0', 'Exhausted memory B-cell': '0.7', 'Progenitor cell': '2.3', 'Memory T-reg': '1.3', 'Naive CD4 T-cell activated': '0.3', 'Naive CD8 T-cell activated': '0.6', 'Naive T-reg': '0.1'} | 1O6S, 2O72, 2OMT, 2OMU, 2OMV, 2OMX, 2OMY, 2OMZ, 3FF7, 3FF8, 3L6X, 3L6Y, 4ZT1, 4ZTE, 6CXY, 6OLE, 6OLF, 6OLG, 6VEL, 7STZ, 8H62 | {'Adipose Tissue': 1.2125261088039867, 'Adrenal Gland': 0.1914223992248062, 'Bladder': 39.2033519047619, 'Blood': 1.340954264800861, 'Blood Vessel': 0.3121561692883895, 'Brain': 0.8550442199091597, 'Breast': 38.54918344226579, 'Cervix Uteri': 23.539115789473684, 'Colon': 43.41292142490372, 'Esophagus': 53.97513367404844, 'Fallopian Tube': 14.900277777777776, 'Heart': 0.119140469221835, 'Kidney': 25.040449438202245, 'Liver': 26.60802654867257, 'Lung': 35.447986366782004, 'Muscle': 0.1378936151930261, 'Nerve': 17.518468982229404, 'Ovary': 3.6515122222222223, 'Pancreas': 56.89676829268293, 'Pituitary': 24.68741660777385, 'Prostate': 61.279967346938776, 'Salivary Gland': 92.01685185185184, 'Skin': 79.77571720232172, 'Small Intestine': 71.7519320855615, 'Spleen': 10.061029045643156, 'Stomach': 58.07813805013927, 'Testis': 0.8144204986149585, 'Thyroid': 135.176797856049, 'Uterus': 1.442593943661972, 'Vagina': 86.52345512820513} | USP37 | MSPLKIHGPIRIRSMQTGITKWKEGSFEIVEKENKVSLVVHYNTGGIPRIFQLSHNIKNVVLRPSGAKQSRLMLTLQDNSFLSIDKVPSKDAEEMRLFLDAVHQNRLPAAMKPSQGSGSFGAILGSRTSQKETSRQLSYSDNQASAKRGSLETKDDIPFRKVLGNPGRGSIKTVAGSGIARTIPSLTSTSTPLRSGLLENRTEKRKRMISTGSELNEDYPKENDSSSNNKAMTDPSRKYLTSSREKQLSLKQSEENRTSGLLPLQSSSFYGSRAGSKEHSSGGTNLDRTNVSSQTPSAKRSLGFLPQPVPLSVKKLRCNQDYTGWNKPRVPLSSHQQQQLQGFSNLGNTCYMNAILQSLFSLQSFANDLLKQGIPWKKIPLNALIRRFAHLLVKKDICNSETKKDLLKKVKNAISATAERFSGYMQNDAHEFLSQCLDQLKEDMEKLNKTWKTEPVSGEENSPDISATRAYTCPVITNLEFEVQHSIICKACGEIIPKREQFNDLSIDLPRRKKPLPPRSIQDSLDLFFRAEELEYSCEKCGGKCALVRHKFNRLPRVLILHLKRYSFNVALSLNNKIGQQVIIPRYLTLSSHCTENTKPPFTLGWSAHMAISRPLKASQMVNSCITSPSTPSKKFTFKSKSSLALCLDSDSEDELKRSVALSQRLCEMLGNEQQQEDLEKDSKLCPIEPDKSELENSGFDRMSEEELLAAVLEISKRDASPSLSHEDDDKPTSSPDTGFAEDDIQEMPENPDTMETEKPKTITELDPASFTEITKDCDENKENKTPEGSQGEVDWLQQYDMEREREEQELQQALAQSLQEQEAWEQKEDDDLKRATELSLQEFNNSFVDALGSDEDSGNEDVFDMEYTEAEAEELKRNAETGNLPHSYRLISVVSHIGSTSSSGHYISDVYDIKKQAWFTYNDLEVSKIQEAAVQSDRDRSGYIFFYMHKEIFDELLETEKNSQSLSTEVGKTTRQAL | Homo sapiens | Nucleus, Chromosome | Low tissue specificity | {'Ciliated cells': '11.3', 'Basal respiratory cells': '7.5', 'Club cells': '9.7', 'Ionocytes': '9.2', 'Mucus glandular cells': '18.6', 'Serous glandular cells': '5.2', 'Gastric mucus-secreting cells': '7.1', 'Proximal enterocytes': '6.1', 'Paneth cells': '8.2', 'Distal enterocytes': '5.5', 'Intestinal goblet cells': '7.8', 'Exocrine glandular cells': '-0.559', 'Basal prostatic cells': '11.4', 'Prostatic glandular cells': '12.8', 'Breast glandular cells': '0.449', 'Breast myoepithelial cells': '0.553', 'Glandular and luminal cells': '15.8', 'Secretory cells': '9.3', 'Basal keratinocytes': '15.2', 'Suprabasal keratinocytes': '16.2', 'Basal squamous epithelial cells': '18.6', 'Squamous epithelial cells': '12.2', 'Alveolar cells type 1': '0.186', 'Alveolar cells type 2': '-0.079', 'Salivary duct cells': '15.6', 'Ductal cells': '0.560', 'Hepatocytes': '0.452', 'Cholangiocytes': '0.0', 'Proximal tubular cells': '0.210', 'Distal tubular cells': '0.0', 'Collecting duct cells': '5.8', 'Mesothelial cells': '0.253', 'Sertoli cells': '-0.228', 'Granulosa cells': '19.2', 'Enteroendocrine cells': '8.2', 'Pancreatic endocrine cells': '8.5', 'Leydig cells': '-0.300', 'Excitatory neurons': '45.8', 'Inhibitory neurons': '38.4', 'Cone photoreceptor cells': '6.8', 'Rod photoreceptor cells': '20.2', 'Bipolar cells': '8.9', 'Horizontal cells': '22.0', 'Astrocytes': '32.5', 'Oligodendrocyte precursor cells': '33.0', 'Oligodendrocytes': '56.3', 'Microglial cells': '25.9', 'Muller glia cells': '8.6', 'Schwann cells': '0.092', 'Spermatogonia': '0.113', 'Spermatocytes': '0.495', 'Early spermatids': '0.494', 'Late spermatids': '0.415', 'Oocytes': '33.1', 'Cytotrophoblasts': '8.5', 'Syncytiotrophoblasts': '7.1', 'Extravillous trophoblasts': '7.1', 'Endothelial cells': '12.2', 'Lymphatic endothelial cells': '9.2', 'Cardiomyocytes': '0.569', 'Skeletal myocytes': '0.036', 'Smooth muscle cells': '18.6', 'Adipocytes': '12.8', 'Melanocytes': '0.245', 'Fibroblasts': '11.0', 'Peritubular cells': '-0.203', 'Endometrial stromal cells': '11.2', 'Ovarian stromal cells': '12.3', 'Undifferentiated cells': '9.0', 'T-cells': '17.7', 'B-cells': '15.8', 'Plasma cells': '11.4', 'Nk-cells': '14.6', 'Granulocytes': '15.4', 'Monocytes': '13.0', 'Macrophages': '19.6', 'Hofbauer cells': '7.6', 'Kupffer cells': '7.5', 'Dendritic cells': '12.8', 'Langerhans cells': '0.254', 'Erythroid cells': '-0.066', 'Adipocytes (Subcutaneous)': '-0.404', 'Adipocytes (Visceral)': '-0.344', 'Breast glandular cells (progenitors)': '0.337', 'Adipocytes (Breast)': '-0.499', 'Colon enterocytes': '0.002', 'Colon enteroendocrine cells': '0.224', 'Enteric glia cells': '-0.191', 'Mitotic cells (Colon)': '0.123', 'Mitotic cells (Heart)': '0.471', 'Podocytes': '-0.048', 'Ascending Loop of Henle cells': '0.371', 'Intercalated cells': '0.049', 'Cholangiocyte': '0.287', 'NK-cells (Liver)': '-0.328', 'Respiratory ciliated cells': '0.055', 'Mitotic cells (Lung)': '-0.038', 'NK-cells (Lung)': '0.241', 'B-cells (Lung)': '0.102', 'Alpha cells': '0.312', 'Beta cells': '0.165', 'Prostate glandular cells': '-0.085', 'Prostate basal glandular cells': '0.223', 'Urothelial cells': '0.174', 'Keratinocyte (other)': '0.361', 'Keratinocyte (granular)': '-0.067', 'Hair cortex cells': '-0.038', 'Inner root sheath cells': '0.016', 'Outer root sheath cells': '0.142', 'Sebaceous gland cells': '0.057', 'Eccrine sweat gland cells': '0.023', 'Adipocytes (Skin)': '-0.175', 'Mitotic cells (Skin)': '0.388', 'Parietal cells': '-0.522', 'Chief cells': '-0.465', 'Gastric mucous cells': '-0.313', 'Gastric enteroendocrine cells': '-0.311', 'Mitotic cells (Stomach)': '0.043', 'Parafollicular cells': '0.052', 'Thyroid glandular cells': '0.288', 'Mitotic cells (Thyroid)': '0.053', 'Adrenal cortex cells': '0.348', 'Adrenal medulla cells': '0.047', 'Mitotic cells (Adrenal gland)': '0.160', 'Minor salivary glandular cells': '0.413', 'Minor salivary gland ductal cells': '0.247', 'Minor salivary gland basal cells': '0.291', 'Mitotic cells (Minor salivary gland)': '0.234', 'Adipocytes (Minor salivary gland)': '0.133', 'Somatotropes': '-0.052', 'Lactotropes': '0.043', 'Gonadotropes': '0.116', 'Corticotropes': '-0.121', 'Thyrotropes': '0.060', 'Undifferentiated cells (Pituitary gland)': '0.018', 'Mitotic cells (Spleen)': '0.074', 'Platelets': '-0.129', 'Erythrocytes': '-0.068', 'Hematopoietic stem cells': '-0.206', 'B-cells (Spleen)': '0.213', 'NK-cells (Spleen)': '0.198', 'Amygdala excitatory': '77.8', 'Cerebellar inhibitory': '58.2', 'Cge interneuron': '54.8', 'Deep-layer corticothalamic and 6b': '70.5', 'Deep-layer intratelencephalic': '68.9', 'Deep-layer near-projecting': '58.8', 'Eccentric medium spiny neuron': '79.1', 'Hippocampal ca1-3': '64.5', 'Hippocampal ca4': '61.1', 'Hippocampal dentate gyrus': '71.6', 'Lamp5-lhx6 and chandelier': '51.3', 'Lower rhombic lip': '49.4', 'Mammillary body': '61.2', 'Medium spiny neuron': '108.0', 'Mge interneuron': '54.2', 'Midbrain-derived inhibitory': '58.3', 'Miscellaneous': '62.9', 'Splatter': '56.4', 'Thalamic excitatory': '52.7', 'Upper rhombic lip': '79.8', 'Upper-layer intratelencephalic': '70.5', 'Astrocyte': '70.9', 'Bergmann glia': '67.0', 'Central nervous system macrophage': '101.1', 'Choroid plexus epithelial cell': '52.2', 'Committed oligodendrocyte precursor': '55.1', 'Ependymal cell': '59.8', 'Oligodendrocyte': '94.5', 'Oligodendrocyte precursor cell': '59.9', 'Endothelial cell': '79.6', 'Pericyte': '67.8', 'Vascular associated smooth muscle cell': '95.5', 'Fibroblast': '75.4', 'Leukocyte': '80.5', 'Basophil': '23.7', 'Eosinophil': '3.8', 'Neutrophil': '10.4', 'Classical monocyte': '4.6', 'Non-classical monocyte': '10.3', 'Intermediate monocyte': '14.1', 'T-reg': '24.3', 'GdT-cell': '3.1', 'MAIT T-cell': '27.5', 'Memory CD4 T-cell': '2.6', 'Naive CD4 T-cell': '18.7', 'Memory CD8 T-cell': '2.7', 'Naive CD8 T-cell': '14.6', 'Memory B-cell': '2.5', 'Naive B-cell': '19.4', 'Plasmacytoid DC': '11.0', 'Myeloid DC': '10.7', 'NK-cell': '14.1', 'Total PBMC': '12.2', 'Vd2 gdTCR': '22.4', 'Memory CD4 T-cell TFH': '13.0', 'Memory CD4 T-cell Th2': '15.9', 'Memory CD4 T-cell Th17': '13.9', 'Memory CD4 T-cell Th1\\/Th17': '15.0', 'Non-Vd2 gdTCR': '22.0', 'Memory CD4 T-cell Th1': '13.8', 'Terminal effector memory CD4 T-cell': '29.7', 'Central memory CD8 T-cell': '23.2', 'Effector memory CD8 T-cell': '20.2', 'Terminal effector memory CD8 T-cell': '21.2', 'Switched memory B-cell': '20.3', 'Plasmablast': '11.7', 'Non-switched memory B-cell': '20.7', 'Exhausted memory B-cell': '18.9', 'Progenitor cell': '16.9', 'Memory T-reg': '12.4', 'Naive CD4 T-cell activated': '33.4', 'Naive CD8 T-cell activated': '27.2', 'Naive T-reg': '17.6'} | 3U12 | {'Adipose Tissue': 3.21072084717608, 'Adrenal Gland': 2.0273151162790697, 'Bladder': 2.9935047619047617, 'Blood': 2.6654355543595263, 'Blood Vessel': 3.063154531835206, 'Brain': 1.175899799394398, 'Breast': 3.1753529411764707, 'Cervix Uteri': 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0.32, 0.16, 0.57, 0.53, 0.29, 0.16, 0.66, 0.11, 0.83, 0.19, 0.61, 0.25, 0.01, 0.24, 0.56, 0.2, 0.02, 0.18, 0.49, 0.06, 0.0, 0.02, 0.0, 0.01, 0.0, 0.0, 0.0, 0.03, 0.25, 0.69, 0.08, 0.07, 0.36, 0.28, 0.01, 0.12, 0.6, 0.34, 0.12, 0.45, 0.57, 0.45, 0.39, 0.47, 0.6, 0.66, 0.5, 0.67, 0.6, 0.47, 0.59, 0.59, 0.54, 0.84, 0.85, 0.82, 0.83] | null | Component of an E-cadherin/ catenin adhesion complex composed of at least E-cadherin/CDH1, beta-catenin/CTNNB1 or gamma-catenin/JUP, and potentially alpha-catenin/CTNNA1. Forms a ternary complex composed of ADAM10, CADH1 and EPHA4, | null | null | KLRG1, SPEF1, DLGAP5, AJAP1, RAPGEF2, RAB8B, PIP5K1C, PKP2, TRPV4, CTNNB1, CAV1, DDR1, TBC1D2, CTNNA1, JUP, CTNND1, PSEN1, LIMA1, CDH1, JUP, ADAM10, CADH1 , EPHA4, | null | null | null | null | Homodimer | null | 79.91949 | 0.474025 | 63.181614 | 0.5857 | 532 |
P12830 | Q86WB0 | null | degron_data | CDH1 | MGPWSRSLSALLLLLQVSSWLCQEPEPCHPGFDAESYTFTVPRRHLERGRVLGRVNFEDCTGRQRTAYFSLDTRFKVGTDGVITVKRPLRFHNPQIHFLVYAWDSTYRKFSTKVTLNTVGHHHRPPPHQASVSGIQAELLTFPNSSPGLRRQKRDWVIPPISCPENEKGPFPKNLVQIKSNKDKEGKVFYSITGQGADTPPVGVFIIERETGWLKVTEPLDRERIATYTLFSHAVSSNGNAVEDPMEILITVTDQNDNKPEFTQEVFKGSVMEGALPGTSVMEVTATDADDDVNTYNAAIAYTILSQDPELPDKNMFTINRNTGVISVVTTGLDRESFPTYTLVVQAADLQGEGLSTTATAVITVTDTNDNPPIFNPTTYKGQVPENEANVVITTLKVTDADAPNTPAWEAVYTILNDDGGQFVVTTNPVNNDGILKTAKGLDFEAKQQYILHVAVTNVVPFEVSLTTSTATVTVDVLDVNEAPIFVPPEKRVEVSEDFGVGQEITSYTAQEPDTFMEQKITYRIWRDTANWLEINPDTGAISTRAELDREDFEHVKNSTYTALIIATDNGSPVATGTGTLLLILSDVNDNAPIPEPRTIFFCERNPKPQVINIIDADLPPNTSPFTAELTHGASANWTIQYNDPTQESIILKPKMALEVGDYKINLKLMDNQNKDQVTTLEVSVCDCEGAAGVCRKAQPVEAGLQIPAILGILGGILALLILILLLLLFLRRRAVVKEPLLPPEDDTRDNVYYYDEEGGGEEDQDFDLSQLHRGLDARPEVTRNDVAPTLMSVPRYLPRPANPDEIGNFIDENLKAADTDPTAPPYDSLLVFDYEGSGSEAASLSSLNSSESDKDQDYDYLNEWGNRFKKLADMYGGGEDD | Homo sapiens | Cell junction, adherens junction, Cell membrane, Endosome, Golgi apparatus, trans-Golgi network, Cytoplasm, Cell junction, desmosome | Tissue enhanced (parathyroid) | {'Ciliated cells': '119.1', 'Basal respiratory cells': '71.1', 'Club cells': '97.3', 'Ionocytes': '81.0', 'Mucus glandular cells': '155.0', 'Serous glandular cells': '67.8', 'Gastric mucus-secreting cells': '133.2', 'Proximal enterocytes': '140.9', 'Paneth cells': '125.1', 'Distal enterocytes': '307.5', 'Intestinal goblet cells': '173.5', 'Exocrine glandular cells': '-0.605', 'Basal prostatic cells': '68.3', 'Prostatic glandular cells': '186.7', 'Breast glandular cells': '0.773', 'Breast myoepithelial cells': '0.700', 'Glandular and luminal cells': '313.0', 'Secretory cells': '82.3', 'Basal keratinocytes': '102.5', 'Suprabasal keratinocytes': '162.6', 'Basal squamous epithelial cells': '51.0', 'Squamous epithelial cells': '106.9', 'Alveolar cells type 1': '0.437', 'Alveolar cells type 2': '0.706', 'Salivary duct cells': '95.9', 'Ductal cells': '0.541', 'Hepatocytes': '0.600', 'Cholangiocytes': '129.7', 'Proximal tubular cells': '0.042', 'Distal tubular cells': '0.0', 'Collecting duct cells': '143.9', 'Mesothelial cells': '0.799', 'Sertoli cells': '0.252', 'Granulosa cells': '12.9', 'Enteroendocrine cells': '92.4', 'Pancreatic endocrine cells': '78.1', 'Leydig cells': '0.264', 'Excitatory neurons': '0.7', 'Inhibitory neurons': '1.3', 'Cone photoreceptor cells': '0.0', 'Rod photoreceptor cells': '0.0', 'Bipolar cells': '0.2', 'Horizontal cells': '0.6', 'Astrocytes': '0.6', 'Oligodendrocyte precursor cells': '0.5', 'Oligodendrocytes': '29.9', 'Microglial cells': '0.9', 'Muller glia cells': '0.1', 'Schwann cells': '0.131', 'Spermatogonia': '0.392', 'Spermatocytes': '0.193', 'Early spermatids': '-0.217', 'Late spermatids': '-0.290', 'Oocytes': '16.9', 'Cytotrophoblasts': '119.2', 'Syncytiotrophoblasts': '45.0', 'Extravillous trophoblasts': '24.9', 'Endothelial cells': '6.1', 'Lymphatic endothelial cells': '0.4', 'Cardiomyocytes': '0.135', 'Skeletal myocytes': '0.107', 'Smooth muscle cells': '5.8', 'Adipocytes': '2.1', 'Melanocytes': '0.335', 'Fibroblasts': '6.5', 'Peritubular cells': '0.210', 'Endometrial stromal cells': '27.7', 'Ovarian stromal cells': '0.7', 'Undifferentiated cells': '101.6', 'T-cells': '2.9', 'B-cells': '4.4', 'Plasma cells': '6.1', 'Nk-cells': '0.0', 'Granulocytes': '8.4', 'Monocytes': '0.0', 'Macrophages': '6.0', 'Hofbauer cells': '4.3', 'Kupffer cells': '1.0', 'Dendritic cells': '5.9', 'Langerhans cells': '0.304', 'Erythroid cells': '0.036', 'Adipocytes (Subcutaneous)': '-0.081', 'Adipocytes (Visceral)': '-0.209', 'Breast glandular cells (progenitors)': '0.538', 'Adipocytes (Breast)': '-0.689', 'Colon enterocytes': '0.790', 'Colon enteroendocrine cells': '0.112', 'Enteric glia cells': '-0.048', 'Mitotic cells (Colon)': '0.299', 'Mitotic cells (Heart)': '0.120', 'Podocytes': '-0.118', 'Ascending Loop of Henle cells': '0.475', 'Intercalated cells': '0.212', 'Cholangiocyte': '0.090', 'NK-cells (Liver)': '-0.005', 'Respiratory ciliated cells': '-0.012', 'Mitotic cells (Lung)': '0.071', 'NK-cells (Lung)': '-0.266', 'B-cells (Lung)': '-0.296', 'Alpha cells': '0.270', 'Beta cells': '0.152', 'Prostate glandular cells': '0.764', 'Prostate basal glandular cells': '0.540', 'Urothelial cells': '0.205', 'Keratinocyte (other)': '0.510', 'Keratinocyte (granular)': '0.055', 'Hair cortex cells': '0.080', 'Inner root sheath cells': '0.131', 'Outer root sheath cells': '0.175', 'Sebaceous gland cells': '0.156', 'Eccrine sweat gland cells': '-0.207', 'Adipocytes (Skin)': '-0.244', 'Mitotic cells (Skin)': '0.442', 'Parietal cells': '0.654', 'Chief cells': '0.649', 'Gastric mucous cells': '0.781', 'Gastric enteroendocrine cells': '0.590', 'Mitotic cells (Stomach)': '0.445', 'Parafollicular cells': '0.173', 'Thyroid glandular cells': '0.865', 'Mitotic cells (Thyroid)': '-0.081', 'Adrenal cortex cells': '0.051', 'Adrenal medulla cells': '0.087', 'Mitotic cells (Adrenal gland)': '0.072', 'Minor salivary glandular cells': '0.371', 'Minor salivary gland ductal cells': '-0.142', 'Minor salivary gland basal cells': '0.582', 'Mitotic cells (Minor salivary gland)': '0.567', 'Adipocytes (Minor salivary gland)': '0.050', 'Somatotropes': '0.121', 'Lactotropes': '0.322', 'Gonadotropes': '0.330', 'Corticotropes': '0.180', 'Thyrotropes': '0.496', 'Undifferentiated cells (Pituitary gland)': '-0.108', 'Mitotic cells (Spleen)': '-0.228', 'Platelets': '-0.050', 'Erythrocytes': '-0.158', 'Hematopoietic stem cells': '-0.211', 'B-cells (Spleen)': '0.266', 'NK-cells (Spleen)': '0.309', 'Amygdala excitatory': '1.0', 'Cerebellar inhibitory': '0.9', 'Cge interneuron': '0.7', 'Deep-layer corticothalamic and 6b': '1.5', 'Deep-layer intratelencephalic': '0.7', 'Deep-layer near-projecting': '0.7', 'Eccentric medium spiny neuron': '0.6', 'Hippocampal ca1-3': '1.9', 'Hippocampal ca4': '1.2', 'Hippocampal dentate gyrus': '1.1', 'Lamp5-lhx6 and chandelier': '0.5', 'Lower rhombic lip': '0.8', 'Mammillary body': '0.6', 'Medium spiny neuron': '0.7', 'Mge interneuron': '1.7', 'Midbrain-derived inhibitory': '0.7', 'Miscellaneous': '0.9', 'Splatter': '3.8', 'Thalamic excitatory': '0.5', 'Upper rhombic lip': '0.8', 'Upper-layer intratelencephalic': '0.6', 'Astrocyte': '4.4', 'Bergmann glia': '0.2', 'Central nervous system macrophage': '0.6', 'Choroid plexus epithelial cell': '52.1', 'Committed oligodendrocyte precursor': '41.5', 'Ependymal cell': '4.8', 'Oligodendrocyte': '53.1', 'Oligodendrocyte precursor cell': '2.4', 'Endothelial cell': '0.7', 'Pericyte': '0.3', 'Vascular associated smooth muscle cell': '0.0', 'Fibroblast': '17.4', 'Leukocyte': '1.1', 'Basophil': '0.0', 'Eosinophil': '0.0', 'Neutrophil': '0.0', 'Classical monocyte': '0.0', 'Non-classical monocyte': '0.0', 'Intermediate monocyte': '0.0', 'T-reg': '2.3', 'GdT-cell': '0.0', 'MAIT T-cell': '0.0', 'Memory CD4 T-cell': '0.0', 'Naive CD4 T-cell': '0.1', 'Memory CD8 T-cell': '0.2', 'Naive CD8 T-cell': '0.3', 'Memory B-cell': '0.0', 'Naive B-cell': '0.1', 'Plasmacytoid DC': '46.6', 'Myeloid DC': '8.5', 'NK-cell': '0.1', 'Total PBMC': '0.7', 'Vd2 gdTCR': '0.0', 'Memory CD4 T-cell Th1\\/Th17': '0.1', 'Memory CD4 T-cell Th17': '0.2', 'Memory CD4 T-cell Th2': '2.9', 'Non-Vd2 gdTCR': '0.1', 'Memory CD4 T-cell Th1': '0.3', 'Memory CD4 T-cell TFH': '0.5', 'Terminal effector memory CD4 T-cell': '0.0', 'Central memory CD8 T-cell': '4.8', 'Effector memory CD8 T-cell': '0.0', 'Terminal effector memory CD8 T-cell': '0.6', 'Non-switched memory B-cell': '0.0', 'Plasmablast': '3.3', 'Switched memory B-cell': '0.0', 'Exhausted memory B-cell': '0.7', 'Progenitor cell': '2.3', 'Memory T-reg': '1.3', 'Naive CD4 T-cell activated': '0.3', 'Naive CD8 T-cell activated': '0.6', 'Naive T-reg': '0.1'} | 1O6S, 2O72, 2OMT, 2OMU, 2OMV, 2OMX, 2OMY, 2OMZ, 3FF7, 3FF8, 3L6X, 3L6Y, 4ZT1, 4ZTE, 6CXY, 6OLE, 6OLF, 6OLG, 6VEL, 7STZ, 8H62 | {'Adipose Tissue': 1.2125261088039867, 'Adrenal Gland': 0.1914223992248062, 'Bladder': 39.2033519047619, 'Blood': 1.340954264800861, 'Blood Vessel': 0.3121561692883895, 'Brain': 0.8550442199091597, 'Breast': 38.54918344226579, 'Cervix Uteri': 23.539115789473684, 'Colon': 43.41292142490372, 'Esophagus': 53.97513367404844, 'Fallopian Tube': 14.900277777777776, 'Heart': 0.119140469221835, 'Kidney': 25.040449438202245, 'Liver': 26.60802654867257, 'Lung': 35.447986366782004, 'Muscle': 0.1378936151930261, 'Nerve': 17.518468982229404, 'Ovary': 3.6515122222222223, 'Pancreas': 56.89676829268293, 'Pituitary': 24.68741660777385, 'Prostate': 61.279967346938776, 'Salivary Gland': 92.01685185185184, 'Skin': 79.77571720232172, 'Small Intestine': 71.7519320855615, 'Spleen': 10.061029045643156, 'Stomach': 58.07813805013927, 'Testis': 0.8144204986149585, 'Thyroid': 135.176797856049, 'Uterus': 1.442593943661972, 'Vagina': 86.52345512820513} | ZC3HC1 | MAAPCEGQAFAVGVEKNWGAVVRSPEGTPQKIRQLIDEGIAPEEGGVDAKDTSATSQSVNGSPQAEQPSLESTSKEAFFSRVETFSSLKWAGKPFELSPLVCAKYGWVTVECDMLKCSSCQAFLCASLQPAFDFDRYKQRCAELKKALCTAHEKFCFWPDSPSPDRFGMLPLDEPAILVSEFLDRFQSLCHLDLQLPSLRPEDLKTMCLTEDKISLLLHLLEDELDHRTDERKTTIKLGSDIQVHVTACILSVCGWACSSSLESMQLSLITCSQCMRKVGLWGFQQIESSMTDLDASFGLTSSPIPGLEGRPERLPLVPESPRRMMTRSQDATFSPGSEQAEKSPGPIVSRTRSWDSSSPVDRPEPEAASPTTRTRPVTRSMGTGDTPGLEVPSSPLRKAKRARLCSSSSSDTSSRSFFDPTSQHRDWCPWVNITLGKESRENGGTEPDASAPAEPGWKAVLTILLAHKQSSQPAETDSMSLSEKSRKVFRIFRQWESLCSC | Homo sapiens | Nucleus, Nucleus envelope | Low tissue specificity | {'Ciliated cells': '4.7', 'Basal respiratory cells': '16.0', 'Club cells': '6.7', 'Ionocytes': '9.2', 'Mucus glandular cells': '3.7', 'Serous glandular cells': '6.9', 'Gastric mucus-secreting cells': '4.1', 'Proximal enterocytes': '2.5', 'Paneth cells': '3.8', 'Distal enterocytes': '3.2', 'Intestinal goblet cells': '3.6', 'Exocrine glandular cells': '-0.674', 'Basal prostatic cells': '5.4', 'Prostatic glandular cells': '4.9', 'Breast glandular cells': '0.229', 'Breast myoepithelial cells': '0.105', 'Glandular and luminal cells': '2.6', 'Secretory cells': '5.8', 'Basal keratinocytes': '3.7', 'Suprabasal keratinocytes': '2.9', 'Basal squamous epithelial cells': '8.2', 'Squamous epithelial cells': '4.4', 'Alveolar cells type 1': '-0.118', 'Alveolar cells type 2': '0.194', 'Salivary duct cells': '4.9', 'Ductal cells': '0.639', 'Hepatocytes': '0.212', 'Cholangiocytes': '0.0', 'Proximal tubular cells': '0.297', 'Distal tubular cells': '24.6', 'Collecting duct cells': '3.9', 'Mesothelial cells': '0.206', 'Sertoli cells': '0.049', 'Granulosa cells': '9.5', 'Enteroendocrine cells': '4.5', 'Pancreatic endocrine cells': '11.9', 'Leydig cells': '-0.044', 'Excitatory neurons': '13.3', 'Inhibitory neurons': '15.1', 'Cone photoreceptor cells': '0.0', 'Rod photoreceptor cells': '4.1', 'Bipolar cells': '7.6', 'Horizontal cells': '3.1', 'Astrocytes': '11.8', 'Oligodendrocyte precursor cells': '10.8', 'Oligodendrocytes': '11.6', 'Microglial cells': '8.9', 'Muller glia cells': '8.1', 'Schwann cells': '0.043', 'Spermatogonia': '0.216', 'Spermatocytes': '0.477', 'Early spermatids': '0.447', 'Late spermatids': '0.003', 'Oocytes': '22.1', 'Cytotrophoblasts': '20.2', 'Syncytiotrophoblasts': '7.2', 'Extravillous trophoblasts': '17.9', 'Endothelial cells': '7.9', 'Lymphatic endothelial cells': '3.1', 'Cardiomyocytes': '0.714', 'Skeletal myocytes': '-0.046', 'Smooth muscle cells': '6.5', 'Adipocytes': '4.7', 'Melanocytes': '0.151', 'Fibroblasts': '7.6', 'Peritubular cells': '-0.144', 'Endometrial stromal cells': '5.4', 'Ovarian stromal cells': '8.1', 'Undifferentiated cells': '6.7', 'T-cells': '6.3', 'B-cells': '7.0', 'Plasma cells': '8.6', 'Nk-cells': '5.2', 'Granulocytes': '8.3', 'Monocytes': '3.7', 'Macrophages': '4.1', 'Hofbauer cells': '8.0', 'Kupffer cells': '5.9', 'Dendritic cells': '4.0', 'Langerhans cells': '0.296', 'Erythroid cells': '0.027', 'Adipocytes (Subcutaneous)': '0.201', 'Adipocytes (Visceral)': '0.144', 'Breast glandular cells (progenitors)': '0.110', 'Adipocytes (Breast)': '0.095', 'Colon enterocytes': '-0.169', 'Colon enteroendocrine cells': '0.227', 'Enteric glia cells': '0.049', 'Mitotic cells (Colon)': '-0.208', 'Mitotic cells (Heart)': '0.489', 'Podocytes': '-0.211', 'Ascending Loop of Henle cells': '0.471', 'Intercalated cells': '-0.082', 'Cholangiocyte': '0.179', 'NK-cells (Liver)': '-0.077', 'Respiratory ciliated cells': '-0.063', 'Mitotic cells (Lung)': '0.227', 'NK-cells (Lung)': '-0.191', 'B-cells (Lung)': '-0.257', 'Alpha cells': '0.383', 'Beta cells': '0.259', 'Prostate glandular cells': '-0.079', 'Prostate basal glandular cells': '0.237', 'Urothelial cells': '0.049', 'Keratinocyte (other)': '0.006', 'Keratinocyte (granular)': '-0.236', 'Hair cortex cells': '0.088', 'Inner root sheath cells': '0.078', 'Outer root sheath cells': '0.286', 'Sebaceous gland cells': '0.270', 'Eccrine sweat gland cells': '0.153', 'Adipocytes (Skin)': '0.148', 'Mitotic cells (Skin)': '0.314', 'Parietal cells': '-0.573', 'Chief cells': '-0.504', 'Gastric mucous cells': '-0.352', 'Gastric enteroendocrine cells': '-0.381', 'Mitotic cells (Stomach)': '0.146', 'Parafollicular cells': '0.011', 'Thyroid glandular cells': '0.253', 'Mitotic cells (Thyroid)': '0.031', 'Adrenal cortex cells': '0.577', 'Adrenal medulla cells': '0.022', 'Mitotic cells (Adrenal gland)': '0.486', 'Minor salivary glandular cells': '0.421', 'Minor salivary gland ductal cells': '0.086', 'Minor salivary gland basal cells': '0.175', 'Mitotic cells (Minor salivary gland)': '0.351', 'Adipocytes (Minor salivary gland)': '0.198', 'Somatotropes': '-0.074', 'Lactotropes': '-0.090', 'Gonadotropes': '-0.006', 'Corticotropes': '-0.011', 'Thyrotropes': '0.087', 'Undifferentiated cells (Pituitary gland)': '0.288', 'Mitotic cells (Spleen)': '-0.205', 'Platelets': '-0.024', 'Erythrocytes': '-0.055', 'Hematopoietic stem cells': '-0.266', 'B-cells (Spleen)': '0.245', 'NK-cells (Spleen)': 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1.0, 0.99, 0.97, 1.0, 0.98, 0.98, 0.98, 0.99, 0.96, 0.88, 0.85, 0.84, 0.9, 0.89, 1.0, 0.91, 0.74, 0.48, 0.62, 0.71, 0.6, 0.54, 0.68, 0.49, 0.56, 0.63, 0.79, 0.66, 0.64, 0.84, 0.87, 0.93, 0.96, 0.97, 0.91, 0.97, 1.0, 0.99, 0.99, 0.99, 1.0, 1.0, 1.0, 0.99, 0.97, 0.98, 0.96, 0.96, 0.96, 0.98, 1.0, 0.96, 0.96, 0.93, 0.81, 0.9, 0.9, 0.85, 0.75, 0.59, 0.31, 0.01, 0.63, 0.17, 0.43, 0.75, 0.24, 0.03, 0.11, 0.57, 0.03, 0.02, 0.48, 0.34, 0.03, 0.34, 0.46, 0.85, 0.33, 0.09, 0.41, 0.79, 0.17, 0.21, 0.44, 0.51, 0.02, 0.05, 0.03, 0.1, 0.22, 0.01, 0.0, 0.2, 0.21, 0.0, 0.0, 0.2, 0.06, 0.35, 0.69, 0.7, 0.18, 0.28, 0.0, 0.27, 0.01, 0.29, 0.37, 0.24, 0.45, 0.08, 0.59, 0.12, 0.54, 0.04, 0.5, 0.18, 0.8, 0.87, 0.38, 0.91, 0.5, 0.68, 0.65, 0.63, 0.28, 0.62, 0.6, 0.53, 0.1, 0.54, 0.4, 0.14, 0.42, 0.67, 0.15, 0.02, 0.31, 0.65, 0.31, 0.12, 0.65, 0.98, 0.98, 0.09, 0.43, 0.0, 0.36, 0.87, 0.33, 0.35, 0.02, 0.25, 0.49, 0.75, 0.08, 0.18, 0.56, 0.14, 0.21, 0.39, 0.94, 0.52, 0.36, 0.7, 0.4, 0.01, 0.04, 0.24, 0.31, 0.0, 0.01, 0.43, 0.09, 0.02, 0.23, 0.21, 0.0, 0.13, 0.59, 0.06, 0.37, 0.16, 0.14, 0.0, 0.0, 0.15, 0.09, 0.43, 0.23, 0.59, 0.16, 0.08, 0.56, 0.75, 0.04, 0.52, 0.1, 0.44, 0.2, 0.63, 0.3, 0.0, 0.05, 0.39, 0.01, 0.0, 0.22, 0.05, 0.03, 0.24, 0.35, 0.3, 0.15, 0.66, 0.68, 0.36, 0.36, 0.88, 0.89, 0.76, 0.89, 0.55, 0.71, 0.38, 0.83, 0.28, 0.85, 0.32, 0.25, 0.2, 0.19, 0.0, 0.02, 0.02, 0.08, 0.0, 0.01, 0.03, 0.0, 0.0, 0.02, 0.03, 0.02, 0.0, 0.23, 0.2, 0.3, 0.87, 0.53, 0.94, 0.65, 0.96, 0.77, 0.66, 0.53, 0.11, 0.23, 0.0, 0.23, 0.03, 0.62, 0.08, 0.0, 0.24, 0.27, 0.64, 0.09, 0.2, 0.0, 0.53, 0.54, 0.1, 0.32, 0.19, 0.04, 0.58, 0.37, 0.69, 0.9, 0.77, 0.89, 0.84, 0.89, 0.81, 0.81, 0.88, 0.93, 1.0, 1.0, 0.99, 0.99, 0.96, 0.99, 0.96, 0.98, 1.0, 1.0, 0.98, 0.98, 1.0, 0.97, 0.98, 0.96, 0.96, 0.94, 0.92, 0.94, 0.91, 0.85, 0.96, 0.95, 0.74, 0.92, 0.87, 0.87, 0.8, 0.93, 0.76, 0.94, 0.73, 0.95, 0.87, 0.98, 0.95, 0.99, 0.99, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 0.98, 1.0, 0.97, 1.0, 0.98, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 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alpha-catenin/CTNNA1. Forms a ternary complex composed of ADAM10, CADH1 and EPHA4, | null | null | KLRG1, SPEF1, DLGAP5, AJAP1, RAPGEF2, RAB8B, PIP5K1C, PKP2, TRPV4, CTNNB1, CAV1, DDR1, TBC1D2, CTNNA1, JUP, CTNND1, PSEN1, LIMA1, CDH1, JUP, ADAM10, CADH1 , EPHA4, | null | null | null | null | Homodimer | null | 79.91949 | 0.474025 | 68.031414 | 0.581952 | 1,580 |
P12830 | Q86XJ1 | null | degron_data | CDH1 | MGPWSRSLSALLLLLQVSSWLCQEPEPCHPGFDAESYTFTVPRRHLERGRVLGRVNFEDCTGRQRTAYFSLDTRFKVGTDGVITVKRPLRFHNPQIHFLVYAWDSTYRKFSTKVTLNTVGHHHRPPPHQASVSGIQAELLTFPNSSPGLRRQKRDWVIPPISCPENEKGPFPKNLVQIKSNKDKEGKVFYSITGQGADTPPVGVFIIERETGWLKVTEPLDRERIATYTLFSHAVSSNGNAVEDPMEILITVTDQNDNKPEFTQEVFKGSVMEGALPGTSVMEVTATDADDDVNTYNAAIAYTILSQDPELPDKNMFTINRNTGVISVVTTGLDRESFPTYTLVVQAADLQGEGLSTTATAVITVTDTNDNPPIFNPTTYKGQVPENEANVVITTLKVTDADAPNTPAWEAVYTILNDDGGQFVVTTNPVNNDGILKTAKGLDFEAKQQYILHVAVTNVVPFEVSLTTSTATVTVDVLDVNEAPIFVPPEKRVEVSEDFGVGQEITSYTAQEPDTFMEQKITYRIWRDTANWLEINPDTGAISTRAELDREDFEHVKNSTYTALIIATDNGSPVATGTGTLLLILSDVNDNAPIPEPRTIFFCERNPKPQVINIIDADLPPNTSPFTAELTHGASANWTIQYNDPTQESIILKPKMALEVGDYKINLKLMDNQNKDQVTTLEVSVCDCEGAAGVCRKAQPVEAGLQIPAILGILGGILALLILILLLLLFLRRRAVVKEPLLPPEDDTRDNVYYYDEEGGGEEDQDFDLSQLHRGLDARPEVTRNDVAPTLMSVPRYLPRPANPDEIGNFIDENLKAADTDPTAPPYDSLLVFDYEGSGSEAASLSSLNSSESDKDQDYDYLNEWGNRFKKLADMYGGGEDD | Homo sapiens | Cell junction, adherens junction, Cell membrane, Endosome, Golgi apparatus, trans-Golgi network, Cytoplasm, Cell junction, desmosome | Tissue enhanced (parathyroid) | {'Ciliated cells': '119.1', 'Basal respiratory cells': '71.1', 'Club cells': '97.3', 'Ionocytes': '81.0', 'Mucus glandular cells': '155.0', 'Serous glandular cells': '67.8', 'Gastric mucus-secreting cells': '133.2', 'Proximal enterocytes': '140.9', 'Paneth cells': '125.1', 'Distal enterocytes': '307.5', 'Intestinal goblet cells': '173.5', 'Exocrine glandular cells': '-0.605', 'Basal prostatic cells': '68.3', 'Prostatic glandular cells': '186.7', 'Breast glandular cells': '0.773', 'Breast myoepithelial cells': '0.700', 'Glandular and luminal cells': '313.0', 'Secretory cells': '82.3', 'Basal keratinocytes': '102.5', 'Suprabasal keratinocytes': '162.6', 'Basal squamous epithelial cells': '51.0', 'Squamous epithelial cells': '106.9', 'Alveolar cells type 1': '0.437', 'Alveolar cells type 2': '0.706', 'Salivary duct cells': '95.9', 'Ductal cells': '0.541', 'Hepatocytes': '0.600', 'Cholangiocytes': '129.7', 'Proximal tubular cells': '0.042', 'Distal tubular cells': '0.0', 'Collecting duct cells': '143.9', 'Mesothelial cells': '0.799', 'Sertoli cells': '0.252', 'Granulosa cells': '12.9', 'Enteroendocrine cells': '92.4', 'Pancreatic endocrine cells': '78.1', 'Leydig cells': '0.264', 'Excitatory neurons': '0.7', 'Inhibitory neurons': '1.3', 'Cone photoreceptor cells': '0.0', 'Rod photoreceptor cells': '0.0', 'Bipolar cells': '0.2', 'Horizontal cells': '0.6', 'Astrocytes': '0.6', 'Oligodendrocyte precursor cells': '0.5', 'Oligodendrocytes': '29.9', 'Microglial cells': '0.9', 'Muller glia cells': '0.1', 'Schwann cells': '0.131', 'Spermatogonia': '0.392', 'Spermatocytes': '0.193', 'Early spermatids': '-0.217', 'Late spermatids': '-0.290', 'Oocytes': '16.9', 'Cytotrophoblasts': '119.2', 'Syncytiotrophoblasts': '45.0', 'Extravillous trophoblasts': '24.9', 'Endothelial cells': '6.1', 'Lymphatic endothelial cells': '0.4', 'Cardiomyocytes': '0.135', 'Skeletal myocytes': '0.107', 'Smooth muscle cells': '5.8', 'Adipocytes': '2.1', 'Melanocytes': '0.335', 'Fibroblasts': '6.5', 'Peritubular cells': '0.210', 'Endometrial stromal cells': '27.7', 'Ovarian stromal cells': '0.7', 'Undifferentiated cells': '101.6', 'T-cells': '2.9', 'B-cells': '4.4', 'Plasma cells': '6.1', 'Nk-cells': '0.0', 'Granulocytes': '8.4', 'Monocytes': '0.0', 'Macrophages': '6.0', 'Hofbauer cells': '4.3', 'Kupffer cells': '1.0', 'Dendritic cells': '5.9', 'Langerhans cells': '0.304', 'Erythroid cells': '0.036', 'Adipocytes (Subcutaneous)': '-0.081', 'Adipocytes (Visceral)': '-0.209', 'Breast glandular cells (progenitors)': '0.538', 'Adipocytes (Breast)': '-0.689', 'Colon enterocytes': '0.790', 'Colon enteroendocrine cells': '0.112', 'Enteric glia cells': '-0.048', 'Mitotic cells (Colon)': '0.299', 'Mitotic cells (Heart)': '0.120', 'Podocytes': '-0.118', 'Ascending Loop of Henle cells': '0.475', 'Intercalated cells': '0.212', 'Cholangiocyte': '0.090', 'NK-cells (Liver)': '-0.005', 'Respiratory ciliated cells': '-0.012', 'Mitotic cells (Lung)': '0.071', 'NK-cells (Lung)': '-0.266', 'B-cells (Lung)': '-0.296', 'Alpha cells': '0.270', 'Beta cells': '0.152', 'Prostate glandular cells': '0.764', 'Prostate basal glandular cells': '0.540', 'Urothelial cells': '0.205', 'Keratinocyte (other)': '0.510', 'Keratinocyte (granular)': '0.055', 'Hair cortex cells': '0.080', 'Inner root sheath cells': '0.131', 'Outer root sheath cells': '0.175', 'Sebaceous gland cells': '0.156', 'Eccrine sweat gland cells': '-0.207', 'Adipocytes (Skin)': '-0.244', 'Mitotic cells (Skin)': '0.442', 'Parietal cells': '0.654', 'Chief cells': '0.649', 'Gastric mucous cells': '0.781', 'Gastric enteroendocrine cells': '0.590', 'Mitotic cells (Stomach)': '0.445', 'Parafollicular cells': '0.173', 'Thyroid glandular cells': '0.865', 'Mitotic cells (Thyroid)': '-0.081', 'Adrenal cortex cells': '0.051', 'Adrenal medulla cells': '0.087', 'Mitotic cells (Adrenal gland)': '0.072', 'Minor salivary glandular cells': '0.371', 'Minor salivary gland ductal cells': '-0.142', 'Minor salivary gland basal cells': '0.582', 'Mitotic cells (Minor salivary gland)': '0.567', 'Adipocytes (Minor salivary gland)': '0.050', 'Somatotropes': '0.121', 'Lactotropes': '0.322', 'Gonadotropes': '0.330', 'Corticotropes': '0.180', 'Thyrotropes': '0.496', 'Undifferentiated cells (Pituitary gland)': '-0.108', 'Mitotic cells (Spleen)': '-0.228', 'Platelets': '-0.050', 'Erythrocytes': '-0.158', 'Hematopoietic stem cells': '-0.211', 'B-cells (Spleen)': '0.266', 'NK-cells (Spleen)': '0.309', 'Amygdala excitatory': '1.0', 'Cerebellar inhibitory': '0.9', 'Cge interneuron': '0.7', 'Deep-layer corticothalamic and 6b': '1.5', 'Deep-layer intratelencephalic': '0.7', 'Deep-layer near-projecting': '0.7', 'Eccentric medium spiny neuron': '0.6', 'Hippocampal ca1-3': '1.9', 'Hippocampal ca4': '1.2', 'Hippocampal dentate gyrus': '1.1', 'Lamp5-lhx6 and chandelier': '0.5', 'Lower rhombic lip': '0.8', 'Mammillary body': '0.6', 'Medium spiny neuron': '0.7', 'Mge interneuron': '1.7', 'Midbrain-derived inhibitory': '0.7', 'Miscellaneous': '0.9', 'Splatter': '3.8', 'Thalamic excitatory': '0.5', 'Upper rhombic lip': '0.8', 'Upper-layer intratelencephalic': '0.6', 'Astrocyte': '4.4', 'Bergmann glia': '0.2', 'Central nervous system macrophage': '0.6', 'Choroid plexus epithelial cell': '52.1', 'Committed oligodendrocyte precursor': '41.5', 'Ependymal cell': '4.8', 'Oligodendrocyte': '53.1', 'Oligodendrocyte precursor cell': '2.4', 'Endothelial cell': '0.7', 'Pericyte': '0.3', 'Vascular associated smooth muscle cell': '0.0', 'Fibroblast': '17.4', 'Leukocyte': '1.1', 'Basophil': '0.0', 'Eosinophil': '0.0', 'Neutrophil': '0.0', 'Classical monocyte': '0.0', 'Non-classical monocyte': '0.0', 'Intermediate monocyte': '0.0', 'T-reg': '2.3', 'GdT-cell': '0.0', 'MAIT T-cell': '0.0', 'Memory CD4 T-cell': '0.0', 'Naive CD4 T-cell': '0.1', 'Memory CD8 T-cell': '0.2', 'Naive CD8 T-cell': '0.3', 'Memory B-cell': '0.0', 'Naive B-cell': '0.1', 'Plasmacytoid DC': '46.6', 'Myeloid DC': '8.5', 'NK-cell': '0.1', 'Total PBMC': '0.7', 'Vd2 gdTCR': '0.0', 'Memory CD4 T-cell Th1\\/Th17': '0.1', 'Memory CD4 T-cell Th17': '0.2', 'Memory CD4 T-cell Th2': '2.9', 'Non-Vd2 gdTCR': '0.1', 'Memory CD4 T-cell Th1': '0.3', 'Memory CD4 T-cell TFH': '0.5', 'Terminal effector memory CD4 T-cell': '0.0', 'Central memory CD8 T-cell': '4.8', 'Effector memory CD8 T-cell': '0.0', 'Terminal effector memory CD8 T-cell': '0.6', 'Non-switched memory B-cell': '0.0', 'Plasmablast': '3.3', 'Switched memory B-cell': '0.0', 'Exhausted memory B-cell': '0.7', 'Progenitor cell': '2.3', 'Memory T-reg': '1.3', 'Naive CD4 T-cell activated': '0.3', 'Naive CD8 T-cell activated': '0.6', 'Naive T-reg': '0.1'} | 1O6S, 2O72, 2OMT, 2OMU, 2OMV, 2OMX, 2OMY, 2OMZ, 3FF7, 3FF8, 3L6X, 3L6Y, 4ZT1, 4ZTE, 6CXY, 6OLE, 6OLF, 6OLG, 6VEL, 7STZ, 8H62 | {'Adipose Tissue': 1.2125261088039867, 'Adrenal Gland': 0.1914223992248062, 'Bladder': 39.2033519047619, 'Blood': 1.340954264800861, 'Blood Vessel': 0.3121561692883895, 'Brain': 0.8550442199091597, 'Breast': 38.54918344226579, 'Cervix Uteri': 23.539115789473684, 'Colon': 43.41292142490372, 'Esophagus': 53.97513367404844, 'Fallopian Tube': 14.900277777777776, 'Heart': 0.119140469221835, 'Kidney': 25.040449438202245, 'Liver': 26.60802654867257, 'Lung': 35.447986366782004, 'Muscle': 0.1378936151930261, 'Nerve': 17.518468982229404, 'Ovary': 3.6515122222222223, 'Pancreas': 56.89676829268293, 'Pituitary': 24.68741660777385, 'Prostate': 61.279967346938776, 'Salivary Gland': 92.01685185185184, 'Skin': 79.77571720232172, 'Small Intestine': 71.7519320855615, 'Spleen': 10.061029045643156, 'Stomach': 58.07813805013927, 'Testis': 0.8144204986149585, 'Thyroid': 135.176797856049, 'Uterus': 1.442593943661972, 'Vagina': 86.52345512820513} | GAS2L3 | MQPAIQVWFGEDLPLSPRSPLTPRHGPGLANVCQYDEWIAVRHEATLLPMQEDLSIWLSGLLGIKVKAEKLLEELDNGVLLCQLIDVLQNMVKTCNSEESGNFPMRKVPCKKDAASGSFFARDNTANFLHWCRDIGVDETYLFESEGLVLHKDPRQVYLCLLEIGRIVSRYGVEPPVLVKLEKEIELEETLLNTSGPEDSISIPKSCCRHEELHEAVKHIAEDPPCSCSHRFSIEYLSEGRYRLGDKILFIRMLHGKHVMVRVGGGWDTLQGFLLKYDPCRILQFATLEQKILAFQKGVSNESVPDSPARTPQPPEMNPLSAVNMFQKQNSKPSVPVSIPKSKEKQGRPPGALVPASSLKGGNLGSMSVRSKLPNSPAASSHPKLKSSKGITKKPQAPSNNASSSLASLNPVGKNTSSPALPRTAPCISESPRKCISSPNTPKAKVIPAQNSADLPESTLLPNKCSGKTQPKYLKHNHISSRDNAVSHLAAHSNSSSKCPKLPKANIPVRPKPSFQSSAKMTKTSSKTIATGLGTQSQPSDGAPQAKPVPAQKLKSALNLNQPVSVSSVSPVKATQKSKDKNIVSATKKQPQNKSAFQKTGPSSLKSPGRTPLSIVSLPQSSTKTQTAPKSAQTVAKSQHSTKGPPRSGKTPASIRKPPSSVKDADSGDKKPTAKKKEDDDHYFVMTGSKKPRK | Homo sapiens | Cytoplasm, Cytoplasm, cytoskeleton | Low tissue specificity | {'Ciliated cells': '2.4', 'Basal respiratory cells': '0.5', 'Club cells': '2.7', 'Ionocytes': '0.0', 'Mucus glandular cells': '6.7', 'Serous glandular cells': '2.9', 'Gastric mucus-secreting cells': '11.2', 'Proximal enterocytes': '2.0', 'Paneth cells': '15.7', 'Distal enterocytes': '9.4', 'Intestinal goblet cells': '15.0', 'Exocrine glandular cells': '-0.443', 'Basal prostatic cells': '0.3', 'Prostatic glandular cells': '0.3', 'Breast glandular cells': '0.278', 'Breast myoepithelial cells': '0.318', 'Glandular and luminal cells': '6.3', 'Secretory cells': '0.5', 'Basal keratinocytes': '3.3', 'Suprabasal keratinocytes': '2.5', 'Basal squamous epithelial cells': '3.8', 'Squamous epithelial cells': '4.0', 'Alveolar cells type 1': '0.003', 'Alveolar cells type 2': '-0.132', 'Salivary duct cells': '3.2', 'Ductal cells': '0.613', 'Hepatocytes': '0.340', 'Cholangiocytes': '9.5', 'Proximal tubular cells': '0.600', 'Distal tubular cells': '0.0', 'Collecting duct cells': '0.0', 'Mesothelial cells': '0.077', 'Sertoli cells': '-0.152', 'Granulosa cells': '3.7', 'Enteroendocrine cells': '7.5', 'Pancreatic endocrine cells': '1.7', 'Leydig cells': '-0.166', 'Excitatory neurons': '2.4', 'Inhibitory neurons': 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0.65, 0.49, 0.09, 0.49, 0.27, 0.06, 0.35, 0.57, 0.41, 0.18, 0.29, 0.38, 0.17, 0.45, 0.64, 0.57, 0.06, 0.65, 0.62, 0.45, 0.53, 0.85, 0.64, 0.69, 0.84, 1.0, 1.0, 0.99, 0.99, 1.0, 1.0, 0.99, 1.0, 1.0, 0.95, 0.98, 0.89, 0.92, 0.93, 0.85, 0.8, 0.87, 0.66, 0.88, 0.93, 0.83, 0.94, 0.96, 0.94, 0.98, 0.99, 0.97, 1.0, 1.0, 1.0, 1.0, 1.0, 0.96, 1.0, 0.97, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 0.93, 1.0, 0.82, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 0.99, 0.98, 0.97, 0.96, 0.9, 1.0, 0.86, 0.86, 0.97, 0.86, 1.0, 0.99, 1.0, 0.98, 1.0, 0.98, 1.0, 1.0, 1.0, 1.0, 1.0, 0.99, 1.0, 0.99, 0.99, 1.0, 0.99, 1.0, 1.0, 1.0, 0.98, 1.0, 0.96, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 0.95, 1.0, 0.91, 1.0, 1.0, 1.0, 1.0, 0.96, 1.0, 0.99, 1.0, 1.0, 1.0, 1.0, 1.0, 0.98, 0.98, 0.98, 0.99, 1.0, 1.0, 1.0, 0.98, 1.0, 0.95, 0.89, 0.96, 0.93, 0.96, 0.98, 0.91, 0.94, 0.85, 0.91, 0.9, 0.88, 0.88, 0.94, 0.92, 0.95, 0.95, 0.95, 0.94, 0.99, 1.0, 0.98, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 0.99, 0.8, 0.99, 0.81, 0.99, 0.96, 0.99, 0.95, 1.0, 0.92, 1.0, 0.96, 1.0, 1.0, 0.99, 1.0, 0.99, 0.89, 0.97, 0.93, 0.98, 0.99, 0.97, 1.0, 0.97, 1.0, 0.95, 0.82, 0.93, 0.89, 0.9, 0.95, 0.97, 0.96, 0.96, 0.94, 0.95, 0.94, 1.0, 0.99, 0.99, 1.0, 0.96, 1.0, 0.98, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 0.99, 0.9, 1.0, 0.91, 1.0, 1.0, 1.0, 1.0, 0.96, 1.0, 0.92, 0.9, 1.0, 0.92, 1.0, 0.97, 1.0, 1.0, 0.91, 1.0, 0.72, 1.0, 0.99, 0.96, 0.97, 0.93, 0.89, 0.95, 0.93, 1.0, 0.88, 0.98, 0.9, 0.92, 0.97, 0.93, 1.0, 0.96, 1.0, 0.98, 1.0, 1.0, 0.92, 1.0, 0.68, 0.95, 0.82, 0.81, 0.95, 0.87, 0.83, 0.98, 0.89, 0.98, 0.98, 0.94, 0.98, 0.97, 0.97, 0.97, 1.0, 1.0, 1.0, 1.0, 0.99, 1.0, 1.0, 1.0, 1.0, 1.0, 0.86, 1.0, 0.87, 1.0, 0.98, 0.97, 1.0, 0.99, 1.0, 1.0, 1.0, 1.0, 1.0, 0.99, 0.96, 0.98, 0.96, 0.97, 0.93, 0.96, 0.96, 0.92, 0.94, 0.94, 0.85, 0.88, 0.8, 0.78, 0.86, 0.86, 0.93, 0.81, 0.93, 0.92, 0.98, 0.98, 1.0, 0.98, 0.98, 1.0, 1.0, 1.0, 0.99, 1.0, 0.99, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 0.99, 1.0, 0.99, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 0.97, 0.98, 0.97, 0.99, 0.99, 1.0, 0.99, 1.0, 1.0, 1.0, 1.0, 1.0, 0.98, 0.77, 0.93, 0.78, 0.86, 0.89, 0.66, 0.88, 0.72, 0.79, 0.79, 0.93, 0.94, 0.91, 0.99, 0.98] | null | Component of an E-cadherin/ catenin adhesion complex composed of at least E-cadherin/CDH1, beta-catenin/CTNNB1 or gamma-catenin/JUP, and potentially alpha-catenin/CTNNA1. Forms a ternary complex composed of ADAM10, CADH1 and EPHA4, | null | null | KLRG1, SPEF1, DLGAP5, AJAP1, RAPGEF2, RAB8B, PIP5K1C, PKP2, TRPV4, CTNNB1, CAV1, DDR1, TBC1D2, CTNNA1, JUP, CTNND1, PSEN1, LIMA1, CDH1, JUP, ADAM10, CADH1 , EPHA4, | null | null | null | null | Homodimer | null | 79.91949 | 0.474025 | 59.767997 | 0.715202 | 1,036 |
P12830 | Q8IWB6-3 | null | degron_data | CDH1 | MGPWSRSLSALLLLLQVSSWLCQEPEPCHPGFDAESYTFTVPRRHLERGRVLGRVNFEDCTGRQRTAYFSLDTRFKVGTDGVITVKRPLRFHNPQIHFLVYAWDSTYRKFSTKVTLNTVGHHHRPPPHQASVSGIQAELLTFPNSSPGLRRQKRDWVIPPISCPENEKGPFPKNLVQIKSNKDKEGKVFYSITGQGADTPPVGVFIIERETGWLKVTEPLDRERIATYTLFSHAVSSNGNAVEDPMEILITVTDQNDNKPEFTQEVFKGSVMEGALPGTSVMEVTATDADDDVNTYNAAIAYTILSQDPELPDKNMFTINRNTGVISVVTTGLDRESFPTYTLVVQAADLQGEGLSTTATAVITVTDTNDNPPIFNPTTYKGQVPENEANVVITTLKVTDADAPNTPAWEAVYTILNDDGGQFVVTTNPVNNDGILKTAKGLDFEAKQQYILHVAVTNVVPFEVSLTTSTATVTVDVLDVNEAPIFVPPEKRVEVSEDFGVGQEITSYTAQEPDTFMEQKITYRIWRDTANWLEINPDTGAISTRAELDREDFEHVKNSTYTALIIATDNGSPVATGTGTLLLILSDVNDNAPIPEPRTIFFCERNPKPQVINIIDADLPPNTSPFTAELTHGASANWTIQYNDPTQESIILKPKMALEVGDYKINLKLMDNQNKDQVTTLEVSVCDCEGAAGVCRKAQPVEAGLQIPAILGILGGILALLILILLLLLFLRRRAVVKEPLLPPEDDTRDNVYYYDEEGGGEEDQDFDLSQLHRGLDARPEVTRNDVAPTLMSVPRYLPRPANPDEIGNFIDENLKAADTDPTAPPYDSLLVFDYEGSGSEAASLSSLNSSESDKDQDYDYLNEWGNRFKKLADMYGGGEDD | Homo sapiens | Cell junction, adherens junction, Cell membrane, Endosome, Golgi apparatus, trans-Golgi network, Cytoplasm, Cell junction, desmosome | Tissue enhanced (parathyroid) | {'Ciliated cells': '119.1', 'Basal respiratory cells': '71.1', 'Club cells': '97.3', 'Ionocytes': '81.0', 'Mucus glandular cells': '155.0', 'Serous glandular cells': '67.8', 'Gastric mucus-secreting cells': '133.2', 'Proximal enterocytes': '140.9', 'Paneth cells': '125.1', 'Distal enterocytes': '307.5', 'Intestinal goblet cells': '173.5', 'Exocrine glandular cells': '-0.605', 'Basal prostatic cells': '68.3', 'Prostatic glandular cells': '186.7', 'Breast glandular cells': '0.773', 'Breast myoepithelial cells': '0.700', 'Glandular and luminal cells': '313.0', 'Secretory cells': '82.3', 'Basal keratinocytes': '102.5', 'Suprabasal keratinocytes': '162.6', 'Basal squamous epithelial cells': '51.0', 'Squamous epithelial cells': '106.9', 'Alveolar cells type 1': '0.437', 'Alveolar cells type 2': '0.706', 'Salivary duct cells': '95.9', 'Ductal cells': '0.541', 'Hepatocytes': '0.600', 'Cholangiocytes': '129.7', 'Proximal tubular cells': '0.042', 'Distal tubular cells': '0.0', 'Collecting duct cells': '143.9', 'Mesothelial cells': '0.799', 'Sertoli cells': '0.252', 'Granulosa cells': '12.9', 'Enteroendocrine cells': '92.4', 'Pancreatic endocrine cells': '78.1', 'Leydig cells': '0.264', 'Excitatory neurons': '0.7', 'Inhibitory neurons': '1.3', 'Cone photoreceptor cells': '0.0', 'Rod photoreceptor cells': '0.0', 'Bipolar cells': '0.2', 'Horizontal cells': '0.6', 'Astrocytes': '0.6', 'Oligodendrocyte precursor cells': '0.5', 'Oligodendrocytes': '29.9', 'Microglial cells': '0.9', 'Muller glia cells': '0.1', 'Schwann cells': '0.131', 'Spermatogonia': '0.392', 'Spermatocytes': '0.193', 'Early spermatids': '-0.217', 'Late spermatids': '-0.290', 'Oocytes': '16.9', 'Cytotrophoblasts': '119.2', 'Syncytiotrophoblasts': '45.0', 'Extravillous trophoblasts': '24.9', 'Endothelial cells': '6.1', 'Lymphatic endothelial cells': '0.4', 'Cardiomyocytes': '0.135', 'Skeletal myocytes': '0.107', 'Smooth muscle cells': '5.8', 'Adipocytes': '2.1', 'Melanocytes': '0.335', 'Fibroblasts': '6.5', 'Peritubular cells': '0.210', 'Endometrial stromal cells': '27.7', 'Ovarian stromal cells': '0.7', 'Undifferentiated cells': '101.6', 'T-cells': '2.9', 'B-cells': '4.4', 'Plasma cells': '6.1', 'Nk-cells': '0.0', 'Granulocytes': '8.4', 'Monocytes': '0.0', 'Macrophages': '6.0', 'Hofbauer cells': '4.3', 'Kupffer cells': '1.0', 'Dendritic cells': '5.9', 'Langerhans cells': '0.304', 'Erythroid cells': '0.036', 'Adipocytes (Subcutaneous)': '-0.081', 'Adipocytes (Visceral)': '-0.209', 'Breast glandular cells (progenitors)': '0.538', 'Adipocytes (Breast)': '-0.689', 'Colon enterocytes': '0.790', 'Colon enteroendocrine cells': '0.112', 'Enteric glia cells': '-0.048', 'Mitotic cells (Colon)': '0.299', 'Mitotic cells (Heart)': '0.120', 'Podocytes': '-0.118', 'Ascending Loop of Henle cells': '0.475', 'Intercalated cells': '0.212', 'Cholangiocyte': '0.090', 'NK-cells (Liver)': '-0.005', 'Respiratory ciliated cells': '-0.012', 'Mitotic cells (Lung)': '0.071', 'NK-cells (Lung)': '-0.266', 'B-cells (Lung)': '-0.296', 'Alpha cells': '0.270', 'Beta cells': '0.152', 'Prostate glandular cells': '0.764', 'Prostate basal glandular cells': '0.540', 'Urothelial cells': '0.205', 'Keratinocyte (other)': '0.510', 'Keratinocyte (granular)': '0.055', 'Hair cortex cells': '0.080', 'Inner root sheath cells': '0.131', 'Outer root sheath cells': '0.175', 'Sebaceous gland cells': '0.156', 'Eccrine sweat gland cells': '-0.207', 'Adipocytes (Skin)': '-0.244', 'Mitotic cells (Skin)': '0.442', 'Parietal cells': '0.654', 'Chief cells': '0.649', 'Gastric mucous cells': '0.781', 'Gastric enteroendocrine cells': '0.590', 'Mitotic cells (Stomach)': '0.445', 'Parafollicular cells': '0.173', 'Thyroid glandular cells': '0.865', 'Mitotic cells (Thyroid)': '-0.081', 'Adrenal cortex cells': '0.051', 'Adrenal medulla cells': '0.087', 'Mitotic cells (Adrenal gland)': '0.072', 'Minor salivary glandular cells': '0.371', 'Minor salivary gland ductal cells': '-0.142', 'Minor salivary gland basal cells': '0.582', 'Mitotic cells (Minor salivary gland)': '0.567', 'Adipocytes (Minor salivary gland)': '0.050', 'Somatotropes': '0.121', 'Lactotropes': '0.322', 'Gonadotropes': '0.330', 'Corticotropes': '0.180', 'Thyrotropes': '0.496', 'Undifferentiated cells (Pituitary gland)': '-0.108', 'Mitotic cells (Spleen)': '-0.228', 'Platelets': '-0.050', 'Erythrocytes': '-0.158', 'Hematopoietic stem cells': '-0.211', 'B-cells (Spleen)': '0.266', 'NK-cells (Spleen)': '0.309', 'Amygdala excitatory': '1.0', 'Cerebellar inhibitory': '0.9', 'Cge interneuron': '0.7', 'Deep-layer corticothalamic and 6b': '1.5', 'Deep-layer intratelencephalic': '0.7', 'Deep-layer near-projecting': '0.7', 'Eccentric medium spiny neuron': '0.6', 'Hippocampal ca1-3': '1.9', 'Hippocampal ca4': '1.2', 'Hippocampal dentate gyrus': '1.1', 'Lamp5-lhx6 and chandelier': '0.5', 'Lower rhombic lip': '0.8', 'Mammillary body': '0.6', 'Medium spiny neuron': '0.7', 'Mge interneuron': '1.7', 'Midbrain-derived inhibitory': '0.7', 'Miscellaneous': '0.9', 'Splatter': '3.8', 'Thalamic excitatory': '0.5', 'Upper rhombic lip': '0.8', 'Upper-layer intratelencephalic': '0.6', 'Astrocyte': '4.4', 'Bergmann glia': '0.2', 'Central nervous system macrophage': '0.6', 'Choroid plexus epithelial cell': '52.1', 'Committed oligodendrocyte precursor': '41.5', 'Ependymal cell': '4.8', 'Oligodendrocyte': '53.1', 'Oligodendrocyte precursor cell': '2.4', 'Endothelial cell': '0.7', 'Pericyte': '0.3', 'Vascular associated smooth muscle cell': '0.0', 'Fibroblast': '17.4', 'Leukocyte': '1.1', 'Basophil': '0.0', 'Eosinophil': '0.0', 'Neutrophil': '0.0', 'Classical monocyte': '0.0', 'Non-classical monocyte': '0.0', 'Intermediate monocyte': '0.0', 'T-reg': '2.3', 'GdT-cell': '0.0', 'MAIT T-cell': '0.0', 'Memory CD4 T-cell': '0.0', 'Naive CD4 T-cell': '0.1', 'Memory CD8 T-cell': '0.2', 'Naive CD8 T-cell': '0.3', 'Memory B-cell': '0.0', 'Naive B-cell': '0.1', 'Plasmacytoid DC': '46.6', 'Myeloid DC': '8.5', 'NK-cell': '0.1', 'Total PBMC': '0.7', 'Vd2 gdTCR': '0.0', 'Memory CD4 T-cell Th1\\/Th17': '0.1', 'Memory CD4 T-cell Th17': '0.2', 'Memory CD4 T-cell Th2': '2.9', 'Non-Vd2 gdTCR': '0.1', 'Memory CD4 T-cell Th1': '0.3', 'Memory CD4 T-cell TFH': '0.5', 'Terminal effector memory CD4 T-cell': '0.0', 'Central memory CD8 T-cell': '4.8', 'Effector memory CD8 T-cell': '0.0', 'Terminal effector memory CD8 T-cell': '0.6', 'Non-switched memory B-cell': '0.0', 'Plasmablast': '3.3', 'Switched memory B-cell': '0.0', 'Exhausted memory B-cell': '0.7', 'Progenitor cell': '2.3', 'Memory T-reg': '1.3', 'Naive CD4 T-cell activated': '0.3', 'Naive CD8 T-cell activated': '0.6', 'Naive T-reg': '0.1'} | 1O6S, 2O72, 2OMT, 2OMU, 2OMV, 2OMX, 2OMY, 2OMZ, 3FF7, 3FF8, 3L6X, 3L6Y, 4ZT1, 4ZTE, 6CXY, 6OLE, 6OLF, 6OLG, 6VEL, 7STZ, 8H62 | {'Adipose Tissue': 1.2125261088039867, 'Adrenal Gland': 0.1914223992248062, 'Bladder': 39.2033519047619, 'Blood': 1.340954264800861, 'Blood Vessel': 0.3121561692883895, 'Brain': 0.8550442199091597, 'Breast': 38.54918344226579, 'Cervix Uteri': 23.539115789473684, 'Colon': 43.41292142490372, 'Esophagus': 53.97513367404844, 'Fallopian Tube': 14.900277777777776, 'Heart': 0.119140469221835, 'Kidney': 25.040449438202245, 'Liver': 26.60802654867257, 'Lung': 35.447986366782004, 'Muscle': 0.1378936151930261, 'Nerve': 17.518468982229404, 'Ovary': 3.6515122222222223, 'Pancreas': 56.89676829268293, 'Pituitary': 24.68741660777385, 'Prostate': 61.279967346938776, 'Salivary Gland': 92.01685185185184, 'Skin': 79.77571720232172, 'Small Intestine': 71.7519320855615, 'Spleen': 10.061029045643156, 'Stomach': 58.07813805013927, 'Testis': 0.8144204986149585, 'Thyroid': 135.176797856049, 'Uterus': 1.442593943661972, 'Vagina': 86.52345512820513} | TEX14 | 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0.18, 0.04, 0.44, 0.59, 0.71, 0.29, 0.52, 0.37, 0.5, 0.11, 0.6, 0.02, 0.48, 0.01, 0.16, 0.04, 0.35, 0.66, 0.47, 0.74, 0.14, 0.62, 0.16, 0.77, 0.79, 0.27, 0.93, 0.69, 0.88, 0.88, 0.85, 0.87, 0.91, 0.92, 0.82, 0.63, 0.75, 0.7, 0.7, 0.38, 0.43, 0.64, 0.55, 0.54, 0.59, 0.45, 0.47, 0.5, 0.58, 0.52, 0.61, 0.57, 0.52, 0.68, 0.44, 0.6, 0.61, 0.58, 0.55, 0.5, 0.61, 0.61, 0.86, 0.86, 0.75, 0.91, 0.96, 0.93, 1.0, 0.87, 0.97, 0.91, 0.95, 0.86, 0.98, 0.93, 0.88, 0.59, 0.87, 0.7, 0.67, 0.85, 0.89, 0.88, 0.91, 0.93, 0.88, 0.99, 0.92, 1.0, 0.79, 0.9, 1.0, 0.94, 1.0, 0.97, 0.96, 0.9, 0.63, 0.68, 0.48, 0.54, 0.8, 0.7, 0.7, 0.95, 0.87, 0.77, 0.84, 0.79, 0.89, 0.95, 0.8, 0.77, 0.51, 0.87, 0.7, 0.52, 0.84, 0.91, 0.51, 0.96, 0.79, 0.92, 0.84, 0.21, 0.89, 0.53, 0.52, 0.89, 0.86, 0.26, 0.91, 0.45, 0.68, 0.84, 0.48, 0.44, 0.51, 0.62, 0.28, 0.59, 0.63, 0.57, 0.15, 0.55, 0.66, 0.1, 0.38, 0.74, 0.65, 0.17, 0.43, 0.66, 0.41, 0.8, 0.75, 0.9, 0.93, 0.52, 0.76, 0.89, 0.87, 0.76, 0.92, 0.91, 0.75, 0.61, 0.96, 0.89, 0.73, 0.97, 0.68, 0.87, 0.55, 0.85, 0.77, 0.69, 0.76, 0.98, 0.83, 0.68, 0.82, 0.74, 0.65, 0.96, 0.93, 0.54, 0.64, 0.28, 0.54, 0.52, 0.16, 0.51, 0.88, 0.6, 0.4, 0.88, 0.95, 0.33, 0.56, 0.73, 0.39, 0.06, 0.61, 0.75, 0.47, 0.19, 0.87, 0.7, 0.97, 0.94, 0.97] | null | null | null | Component of an E-cadherin/ catenin adhesion complex composed of at least E-cadherin/CDH1, beta-catenin/CTNNB1 or gamma-catenin/JUP, and potentially alpha-catenin/CTNNA1. Forms a ternary complex composed of ADAM10, CADH1 and EPHA4, | null | null | KLRG1, SPEF1, DLGAP5, AJAP1, RAPGEF2, RAB8B, PIP5K1C, PKP2, TRPV4, CTNNB1, CAV1, DDR1, TBC1D2, CTNNA1, JUP, CTNND1, PSEN1, LIMA1, CDH1, JUP, ADAM10, CADH1 , EPHA4, | null | null | null | null | Homodimer | null | 79.91949 | 0.474025 | null | null | 212 |
P12830 | Q8IWF2 | null | degron_data | CDH1 | MGPWSRSLSALLLLLQVSSWLCQEPEPCHPGFDAESYTFTVPRRHLERGRVLGRVNFEDCTGRQRTAYFSLDTRFKVGTDGVITVKRPLRFHNPQIHFLVYAWDSTYRKFSTKVTLNTVGHHHRPPPHQASVSGIQAELLTFPNSSPGLRRQKRDWVIPPISCPENEKGPFPKNLVQIKSNKDKEGKVFYSITGQGADTPPVGVFIIERETGWLKVTEPLDRERIATYTLFSHAVSSNGNAVEDPMEILITVTDQNDNKPEFTQEVFKGSVMEGALPGTSVMEVTATDADDDVNTYNAAIAYTILSQDPELPDKNMFTINRNTGVISVVTTGLDRESFPTYTLVVQAADLQGEGLSTTATAVITVTDTNDNPPIFNPTTYKGQVPENEANVVITTLKVTDADAPNTPAWEAVYTILNDDGGQFVVTTNPVNNDGILKTAKGLDFEAKQQYILHVAVTNVVPFEVSLTTSTATVTVDVLDVNEAPIFVPPEKRVEVSEDFGVGQEITSYTAQEPDTFMEQKITYRIWRDTANWLEINPDTGAISTRAELDREDFEHVKNSTYTALIIATDNGSPVATGTGTLLLILSDVNDNAPIPEPRTIFFCERNPKPQVINIIDADLPPNTSPFTAELTHGASANWTIQYNDPTQESIILKPKMALEVGDYKINLKLMDNQNKDQVTTLEVSVCDCEGAAGVCRKAQPVEAGLQIPAILGILGGILALLILILLLLLFLRRRAVVKEPLLPPEDDTRDNVYYYDEEGGGEEDQDFDLSQLHRGLDARPEVTRNDVAPTLMSVPRYLPRPANPDEIGNFIDENLKAADTDPTAPPYDSLLVFDYEGSGSEAASLSSLNSSESDKDQDYDYLNEWGNRFKKLADMYGGGEDD | Homo sapiens | Cell junction, adherens junction, Cell membrane, Endosome, Golgi apparatus, trans-Golgi network, Cytoplasm, Cell junction, desmosome | Tissue enhanced (parathyroid) | {'Ciliated cells': '119.1', 'Basal respiratory cells': '71.1', 'Club cells': '97.3', 'Ionocytes': '81.0', 'Mucus glandular cells': '155.0', 'Serous glandular cells': '67.8', 'Gastric mucus-secreting cells': '133.2', 'Proximal enterocytes': '140.9', 'Paneth cells': '125.1', 'Distal enterocytes': '307.5', 'Intestinal goblet cells': '173.5', 'Exocrine glandular cells': '-0.605', 'Basal prostatic cells': '68.3', 'Prostatic glandular cells': '186.7', 'Breast glandular cells': '0.773', 'Breast myoepithelial cells': '0.700', 'Glandular and luminal cells': '313.0', 'Secretory cells': '82.3', 'Basal keratinocytes': '102.5', 'Suprabasal keratinocytes': '162.6', 'Basal squamous epithelial cells': '51.0', 'Squamous epithelial cells': '106.9', 'Alveolar cells type 1': '0.437', 'Alveolar cells type 2': '0.706', 'Salivary duct cells': '95.9', 'Ductal cells': '0.541', 'Hepatocytes': '0.600', 'Cholangiocytes': '129.7', 'Proximal tubular cells': '0.042', 'Distal tubular cells': '0.0', 'Collecting duct cells': '143.9', 'Mesothelial cells': '0.799', 'Sertoli cells': '0.252', 'Granulosa cells': '12.9', 'Enteroendocrine cells': '92.4', 'Pancreatic endocrine cells': '78.1', 'Leydig cells': '0.264', 'Excitatory neurons': '0.7', 'Inhibitory neurons': '1.3', 'Cone photoreceptor cells': '0.0', 'Rod photoreceptor cells': '0.0', 'Bipolar cells': '0.2', 'Horizontal cells': '0.6', 'Astrocytes': '0.6', 'Oligodendrocyte precursor cells': '0.5', 'Oligodendrocytes': '29.9', 'Microglial cells': '0.9', 'Muller glia cells': '0.1', 'Schwann cells': '0.131', 'Spermatogonia': '0.392', 'Spermatocytes': '0.193', 'Early spermatids': '-0.217', 'Late spermatids': '-0.290', 'Oocytes': '16.9', 'Cytotrophoblasts': '119.2', 'Syncytiotrophoblasts': '45.0', 'Extravillous trophoblasts': '24.9', 'Endothelial cells': '6.1', 'Lymphatic endothelial cells': '0.4', 'Cardiomyocytes': '0.135', 'Skeletal myocytes': '0.107', 'Smooth muscle cells': '5.8', 'Adipocytes': '2.1', 'Melanocytes': '0.335', 'Fibroblasts': '6.5', 'Peritubular cells': '0.210', 'Endometrial stromal cells': '27.7', 'Ovarian stromal cells': '0.7', 'Undifferentiated cells': '101.6', 'T-cells': '2.9', 'B-cells': '4.4', 'Plasma cells': '6.1', 'Nk-cells': '0.0', 'Granulocytes': '8.4', 'Monocytes': '0.0', 'Macrophages': '6.0', 'Hofbauer cells': '4.3', 'Kupffer cells': '1.0', 'Dendritic cells': '5.9', 'Langerhans cells': '0.304', 'Erythroid cells': '0.036', 'Adipocytes (Subcutaneous)': '-0.081', 'Adipocytes (Visceral)': '-0.209', 'Breast glandular cells (progenitors)': '0.538', 'Adipocytes (Breast)': '-0.689', 'Colon enterocytes': '0.790', 'Colon enteroendocrine cells': '0.112', 'Enteric glia cells': '-0.048', 'Mitotic cells (Colon)': '0.299', 'Mitotic cells (Heart)': '0.120', 'Podocytes': '-0.118', 'Ascending Loop of Henle cells': '0.475', 'Intercalated cells': '0.212', 'Cholangiocyte': '0.090', 'NK-cells (Liver)': '-0.005', 'Respiratory ciliated cells': '-0.012', 'Mitotic cells (Lung)': '0.071', 'NK-cells (Lung)': '-0.266', 'B-cells (Lung)': '-0.296', 'Alpha cells': '0.270', 'Beta cells': '0.152', 'Prostate glandular cells': '0.764', 'Prostate basal glandular cells': '0.540', 'Urothelial cells': '0.205', 'Keratinocyte (other)': '0.510', 'Keratinocyte (granular)': '0.055', 'Hair cortex cells': '0.080', 'Inner root sheath cells': '0.131', 'Outer root sheath cells': '0.175', 'Sebaceous gland cells': '0.156', 'Eccrine sweat gland cells': '-0.207', 'Adipocytes (Skin)': '-0.244', 'Mitotic cells (Skin)': '0.442', 'Parietal cells': '0.654', 'Chief cells': '0.649', 'Gastric mucous cells': '0.781', 'Gastric enteroendocrine cells': '0.590', 'Mitotic cells (Stomach)': '0.445', 'Parafollicular cells': '0.173', 'Thyroid glandular cells': '0.865', 'Mitotic cells (Thyroid)': '-0.081', 'Adrenal cortex cells': '0.051', 'Adrenal medulla cells': '0.087', 'Mitotic cells (Adrenal gland)': '0.072', 'Minor salivary glandular cells': '0.371', 'Minor salivary gland ductal cells': '-0.142', 'Minor salivary gland basal cells': '0.582', 'Mitotic cells (Minor salivary gland)': '0.567', 'Adipocytes (Minor salivary gland)': '0.050', 'Somatotropes': '0.121', 'Lactotropes': '0.322', 'Gonadotropes': '0.330', 'Corticotropes': '0.180', 'Thyrotropes': '0.496', 'Undifferentiated cells (Pituitary gland)': '-0.108', 'Mitotic cells (Spleen)': '-0.228', 'Platelets': '-0.050', 'Erythrocytes': '-0.158', 'Hematopoietic stem cells': '-0.211', 'B-cells (Spleen)': '0.266', 'NK-cells (Spleen)': '0.309', 'Amygdala excitatory': '1.0', 'Cerebellar inhibitory': '0.9', 'Cge interneuron': '0.7', 'Deep-layer corticothalamic and 6b': '1.5', 'Deep-layer intratelencephalic': '0.7', 'Deep-layer near-projecting': '0.7', 'Eccentric medium spiny neuron': '0.6', 'Hippocampal ca1-3': '1.9', 'Hippocampal ca4': '1.2', 'Hippocampal dentate gyrus': '1.1', 'Lamp5-lhx6 and chandelier': '0.5', 'Lower rhombic lip': '0.8', 'Mammillary body': '0.6', 'Medium spiny neuron': '0.7', 'Mge interneuron': '1.7', 'Midbrain-derived inhibitory': '0.7', 'Miscellaneous': '0.9', 'Splatter': '3.8', 'Thalamic excitatory': '0.5', 'Upper rhombic lip': '0.8', 'Upper-layer intratelencephalic': '0.6', 'Astrocyte': '4.4', 'Bergmann glia': '0.2', 'Central nervous system macrophage': '0.6', 'Choroid plexus epithelial cell': '52.1', 'Committed oligodendrocyte precursor': '41.5', 'Ependymal cell': '4.8', 'Oligodendrocyte': '53.1', 'Oligodendrocyte precursor cell': '2.4', 'Endothelial cell': '0.7', 'Pericyte': '0.3', 'Vascular associated smooth muscle cell': '0.0', 'Fibroblast': '17.4', 'Leukocyte': '1.1', 'Basophil': '0.0', 'Eosinophil': '0.0', 'Neutrophil': '0.0', 'Classical monocyte': '0.0', 'Non-classical monocyte': '0.0', 'Intermediate monocyte': '0.0', 'T-reg': '2.3', 'GdT-cell': '0.0', 'MAIT T-cell': '0.0', 'Memory CD4 T-cell': '0.0', 'Naive CD4 T-cell': '0.1', 'Memory CD8 T-cell': '0.2', 'Naive CD8 T-cell': '0.3', 'Memory B-cell': '0.0', 'Naive B-cell': '0.1', 'Plasmacytoid DC': '46.6', 'Myeloid DC': '8.5', 'NK-cell': '0.1', 'Total PBMC': '0.7', 'Vd2 gdTCR': '0.0', 'Memory CD4 T-cell Th1\\/Th17': '0.1', 'Memory CD4 T-cell Th17': '0.2', 'Memory CD4 T-cell Th2': '2.9', 'Non-Vd2 gdTCR': '0.1', 'Memory CD4 T-cell Th1': '0.3', 'Memory CD4 T-cell TFH': '0.5', 'Terminal effector memory CD4 T-cell': '0.0', 'Central memory CD8 T-cell': '4.8', 'Effector memory CD8 T-cell': '0.0', 'Terminal effector memory CD8 T-cell': '0.6', 'Non-switched memory B-cell': '0.0', 'Plasmablast': '3.3', 'Switched memory B-cell': '0.0', 'Exhausted memory B-cell': '0.7', 'Progenitor cell': '2.3', 'Memory T-reg': '1.3', 'Naive CD4 T-cell activated': '0.3', 'Naive CD8 T-cell activated': '0.6', 'Naive T-reg': '0.1'} | 1O6S, 2O72, 2OMT, 2OMU, 2OMV, 2OMX, 2OMY, 2OMZ, 3FF7, 3FF8, 3L6X, 3L6Y, 4ZT1, 4ZTE, 6CXY, 6OLE, 6OLF, 6OLG, 6VEL, 7STZ, 8H62 | {'Adipose Tissue': 1.2125261088039867, 'Adrenal Gland': 0.1914223992248062, 'Bladder': 39.2033519047619, 'Blood': 1.340954264800861, 'Blood Vessel': 0.3121561692883895, 'Brain': 0.8550442199091597, 'Breast': 38.54918344226579, 'Cervix Uteri': 23.539115789473684, 'Colon': 43.41292142490372, 'Esophagus': 53.97513367404844, 'Fallopian Tube': 14.900277777777776, 'Heart': 0.119140469221835, 'Kidney': 25.040449438202245, 'Liver': 26.60802654867257, 'Lung': 35.447986366782004, 'Muscle': 0.1378936151930261, 'Nerve': 17.518468982229404, 'Ovary': 3.6515122222222223, 'Pancreas': 56.89676829268293, 'Pituitary': 24.68741660777385, 'Prostate': 61.279967346938776, 'Salivary Gland': 92.01685185185184, 'Skin': 79.77571720232172, 'Small Intestine': 71.7519320855615, 'Spleen': 10.061029045643156, 'Stomach': 58.07813805013927, 'Testis': 0.8144204986149585, 'Thyroid': 135.176797856049, 'Uterus': 1.442593943661972, 'Vagina': 86.52345512820513} | FOXRED2 | MGLSAAAPLWGPPGLLLAIALHPALSVPPRRDYCVLGAGPAGLQMAYFLQRAGRDYAVFERAPRPGSFFTRYPRHRKLISINKRYTGKANAEFNLRHDWNSLLSHDPRLLFRHYSRAYFPDARDMVRYLGDFADTLGLRVQYNTTIAHVTLDKDRQAWNGHYFILTDQKGQVHQCSVLFVATGLSVPNQVDFPGSEYAEGYESVSVDPEDFVGQNVLILGRGNSAFETAENILGVTNFIHMLSRSRVRLSWATHYVGDLRAINNGLLDTYQLKSLDGLLESDLTDLAILKDSKGKFHVTPKFFLEEANTNQSADSITLPQDDNDNFAMRVPYDRVIRCLGWNFDFSIFNKSLRLNSGNAFGKKYPLIRASYESKGSRGLFILGTASHSVDYRKSAGGFIHGFRYTVRAVHRLLEHRHHSVTWPATELPITQLTSSIVRRVNEASGLYQMFGVLADVILLKENSTAFEYLEEFPIQMLAQLETLTGRKAKHGLFVINMEYGRNFSGPDKDVFFDDRSVGHTEDAWQSNFLHPVIYYYRYLPTEQEVRFRPAHWPLPRPTAIHHIVEDFLTDWTAPIGHILPLRRFLENCLDTDLRSFYAESCFLFALTRQKLPPFCQQGYLRMQGLVSTESLWQHRVESRLLRDYAPTGRRLEDSSQQLGDQEPLGSPLAPGPLAQSVDSNKEEL | Homo sapiens | Endoplasmic reticulum lumen | Low tissue specificity | {'Ciliated cells': '1.2', 'Basal respiratory cells': '0.9', 'Club cells': '3.6', 'Ionocytes': '1.5', 'Mucus glandular cells': '7.0', 'Serous glandular cells': '5.9', 'Gastric mucus-secreting cells': '0.6', 'Proximal enterocytes': '0.3', 'Paneth cells': '1.4', 'Distal enterocytes': '0.3', 'Intestinal goblet cells': '1.3', 'Exocrine glandular cells': '-0.009', 'Basal prostatic cells': '3.1', 'Prostatic glandular cells': '11.4', 'Breast glandular cells': '0.439', 'Breast myoepithelial cells': '0.396', 'Glandular and luminal cells': '3.7', 'Secretory cells': '2.3', 'Basal keratinocytes': '4.8', 'Suprabasal keratinocytes': '3.7', 'Basal squamous epithelial cells': '4.2', 'Squamous epithelial cells': '4.5', 'Alveolar cells type 1': '-0.096', 'Alveolar cells type 2': '0.207', 'Salivary duct cells': '4.5', 'Ductal cells': '0.158', 'Hepatocytes': '0.572', 'Cholangiocytes': '3.8', 'Proximal tubular cells': '0.384', 'Distal tubular cells': '0.0', 'Collecting duct cells': '3.9', 'Mesothelial cells': '0.424', 'Sertoli cells': '0.518', 'Granulosa cells': '5.5', 'Enteroendocrine cells': '0.3', 'Pancreatic endocrine cells': '0.0', 'Leydig cells': '0.518', 'Excitatory neurons': '3.4', 'Inhibitory neurons': '8.7', 'Cone photoreceptor cells': '3.4', 'Rod photoreceptor cells': '3.8', 'Bipolar cells': '9.7', 'Horizontal cells': '9.4', 'Astrocytes': '6.5', 'Oligodendrocyte precursor cells': '5.7', 'Oligodendrocytes': '5.1', 'Microglial cells': '0.0', 'Muller glia cells': '6.7', 'Schwann cells': '0.124', 'Spermatogonia': '0.749', 'Spermatocytes': '0.520', 'Early spermatids': '-0.334', 'Late spermatids': '-0.561', 'Oocytes': '8.1', 'Cytotrophoblasts': '11.0', 'Syncytiotrophoblasts': '3.3', 'Extravillous trophoblasts': '4.4', 'Endothelial cells': '2.1', 'Lymphatic endothelial cells': '0.7', 'Cardiomyocytes': '0.738', 'Skeletal myocytes': '0.014', 'Smooth muscle cells': '3.6', 'Adipocytes': '0.9', 'Melanocytes': '0.379', 'Fibroblasts': '6.9', 'Peritubular cells': '0.429', 'Endometrial stromal cells': '5.6', 'Ovarian stromal cells': '9.7', 'Undifferentiated cells': '4.0', 'T-cells': '1.0', 'B-cells': '1.7', 'Plasma cells': '3.8', 'Nk-cells': '0.8', 'Granulocytes': '1.4', 'Monocytes': '0.9', 'Macrophages': '6.0', 'Hofbauer cells': '9.4', 'Kupffer cells': '11.0', 'Dendritic cells': '8.8', 'Langerhans cells': '0.301', 'Erythroid cells': '-0.177', 'Adipocytes (Subcutaneous)': '-0.126', 'Adipocytes (Visceral)': '-0.133', 'Breast glandular cells (progenitors)': '0.542', 'Adipocytes (Breast)': '-0.324', 'Colon enterocytes': '-0.100', 'Colon enteroendocrine cells': '0.395', 'Enteric glia cells': '0.184', 'Mitotic cells (Colon)': '-0.166', 'Mitotic cells (Heart)': '0.366', 'Podocytes': '-0.127', 'Ascending Loop of Henle cells': '0.446', 'Intercalated cells': '0.097', 'Cholangiocyte': '0.119', 'NK-cells (Liver)': '-0.080', 'Respiratory ciliated cells': '-0.056', 'Mitotic cells (Lung)': '0.230', 'NK-cells (Lung)': '-0.164', 'B-cells (Lung)': '-0.180', 'Alpha cells': '0.250', 'Beta cells': '0.080', 'Prostate glandular cells': '0.349', 'Prostate basal glandular cells': '0.251', 'Urothelial cells': '0.050', 'Keratinocyte (other)': '0.309', 'Keratinocyte (granular)': '0.068', 'Hair cortex cells': '0.097', 'Inner root sheath cells': '0.154', 'Outer root sheath cells': '0.045', 'Sebaceous gland cells': '0.132', 'Eccrine sweat gland cells': '-0.118', 'Adipocytes (Skin)': '-0.004', 'Mitotic cells (Skin)': '0.395', 'Parietal cells': '-0.434', 'Chief cells': '-0.159', 'Gastric mucous cells': '-0.354', 'Gastric enteroendocrine cells': '-0.182', 'Mitotic cells (Stomach)': '0.054', 'Parafollicular cells': '0.107', 'Thyroid glandular cells': '0.501', 'Mitotic cells (Thyroid)': '0.017', 'Adrenal cortex cells': '0.652', 'Adrenal medulla cells': '0.032', 'Mitotic cells (Adrenal gland)': '0.336', 'Minor salivary glandular cells': '0.437', 'Minor salivary gland ductal cells': '0.118', 'Minor salivary gland basal cells': '-0.018', 'Mitotic cells (Minor salivary gland)': '0.219', 'Adipocytes (Minor salivary gland)': '-0.005', 'Somatotropes': '-0.109', 'Lactotropes': '0.021', 'Gonadotropes': '0.198', 'Corticotropes': '-0.065', 'Thyrotropes': '0.138', 'Undifferentiated cells (Pituitary gland)': '0.396', 'Mitotic 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0.02, 0.47, 0.08, 0.01, 0.26, 0.37, 0.0, 0.26, 0.79, 0.14, 0.0, 0.38, 0.22, 0.55, 0.11, 0.76, 0.43, 0.0, 0.0, 0.0, 0.01, 0.0, 0.0, 0.02, 0.17, 0.3, 0.15, 0.69, 0.77, 0.04, 0.35, 0.14, 0.27, 0.87, 0.46, 0.57, 0.09, 0.69, 0.4, 0.96, 0.89, 0.31, 0.71, 0.16, 0.8, 0.62, 0.34, 0.8, 0.34, 0.04, 0.76, 0.55, 0.01, 0.15, 0.38, 0.07, 0.02, 0.0, 0.0, 0.0, 0.06, 0.11, 0.04, 0.64, 0.82, 0.25, 0.05, 0.51, 0.57, 0.7, 0.5, 0.09, 0.89, 0.8, 0.26, 0.45, 0.93, 0.73, 0.33, 0.19, 0.0, 0.05, 0.84, 0.22, 0.51, 0.25, 0.47, 0.15, 0.22, 0.03, 0.04, 0.12, 0.28, 0.98, 0.83, 0.19, 0.28, 0.01, 0.45, 0.4, 0.67, 0.77, 0.26, 0.06, 0.33, 0.41, 0.21, 0.0, 0.2, 0.54, 0.13, 0.0, 0.08, 0.79, 0.15, 0.12, 0.74, 0.19, 0.21, 0.09, 0.17, 0.29, 0.01, 0.22, 0.18, 0.53, 0.12, 0.01, 0.51, 0.57, 0.1, 0.43, 0.71, 0.7, 0.47, 0.98, 0.65, 0.17, 0.04, 0.08, 0.21, 0.0, 0.44, 0.24, 0.17, 0.29, 0.63, 0.7, 0.9, 0.61, 0.72, 0.37, 0.85, 0.33, 0.23, 0.7, 0.52, 0.26, 0.46, 0.52, 0.59, 0.42, 0.24, 0.74, 0.48, 0.86, 0.75, 0.44, 0.81, 0.55, 0.8, 0.64, 0.88, 0.85, 0.72, 0.9, 0.94, 0.92, 0.96, 0.96, 1.0, 1.0, 1.0, 1.0, 1.0, 0.99, 1.0, 1.0, 1.0, 1.0, 1.0, 0.88, 0.97, 0.92, 0.94, 0.93, 0.96, 0.87, 0.96, 0.91, 0.85, 0.89, 0.86, 0.79, 0.61, 0.7, 0.82, 0.63, 0.68, 0.45, 0.55] | null | Component of an E-cadherin/ catenin adhesion complex composed of at least E-cadherin/CDH1, beta-catenin/CTNNB1 or gamma-catenin/JUP, and potentially alpha-catenin/CTNNA1. Forms a ternary complex composed of ADAM10, CADH1 and EPHA4, | null | null | KLRG1, SPEF1, DLGAP5, AJAP1, RAPGEF2, RAB8B, PIP5K1C, PKP2, TRPV4, CTNNB1, CAV1, DDR1, TBC1D2, CTNNA1, JUP, CTNND1, PSEN1, LIMA1, CDH1, JUP, ADAM10, CADH1 , EPHA4, | null | null | null | null | Homodimer | null | 79.91949 | 0.474025 | 87.155921 | 0.351447 | 1,061 |
P12830 | Q8IWQ3-5 | null | degron_data | CDH1 | MGPWSRSLSALLLLLQVSSWLCQEPEPCHPGFDAESYTFTVPRRHLERGRVLGRVNFEDCTGRQRTAYFSLDTRFKVGTDGVITVKRPLRFHNPQIHFLVYAWDSTYRKFSTKVTLNTVGHHHRPPPHQASVSGIQAELLTFPNSSPGLRRQKRDWVIPPISCPENEKGPFPKNLVQIKSNKDKEGKVFYSITGQGADTPPVGVFIIERETGWLKVTEPLDRERIATYTLFSHAVSSNGNAVEDPMEILITVTDQNDNKPEFTQEVFKGSVMEGALPGTSVMEVTATDADDDVNTYNAAIAYTILSQDPELPDKNMFTINRNTGVISVVTTGLDRESFPTYTLVVQAADLQGEGLSTTATAVITVTDTNDNPPIFNPTTYKGQVPENEANVVITTLKVTDADAPNTPAWEAVYTILNDDGGQFVVTTNPVNNDGILKTAKGLDFEAKQQYILHVAVTNVVPFEVSLTTSTATVTVDVLDVNEAPIFVPPEKRVEVSEDFGVGQEITSYTAQEPDTFMEQKITYRIWRDTANWLEINPDTGAISTRAELDREDFEHVKNSTYTALIIATDNGSPVATGTGTLLLILSDVNDNAPIPEPRTIFFCERNPKPQVINIIDADLPPNTSPFTAELTHGASANWTIQYNDPTQESIILKPKMALEVGDYKINLKLMDNQNKDQVTTLEVSVCDCEGAAGVCRKAQPVEAGLQIPAILGILGGILALLILILLLLLFLRRRAVVKEPLLPPEDDTRDNVYYYDEEGGGEEDQDFDLSQLHRGLDARPEVTRNDVAPTLMSVPRYLPRPANPDEIGNFIDENLKAADTDPTAPPYDSLLVFDYEGSGSEAASLSSLNSSESDKDQDYDYLNEWGNRFKKLADMYGGGEDD | Homo sapiens | Cell junction, adherens junction, Cell membrane, Endosome, Golgi apparatus, trans-Golgi network, Cytoplasm, Cell junction, desmosome | Tissue enhanced (parathyroid) | {'Ciliated cells': '119.1', 'Basal respiratory cells': '71.1', 'Club cells': '97.3', 'Ionocytes': '81.0', 'Mucus glandular cells': '155.0', 'Serous glandular cells': '67.8', 'Gastric mucus-secreting cells': '133.2', 'Proximal enterocytes': '140.9', 'Paneth cells': '125.1', 'Distal enterocytes': '307.5', 'Intestinal goblet cells': '173.5', 'Exocrine glandular cells': '-0.605', 'Basal prostatic cells': '68.3', 'Prostatic glandular cells': '186.7', 'Breast glandular cells': '0.773', 'Breast myoepithelial cells': '0.700', 'Glandular and luminal cells': '313.0', 'Secretory cells': '82.3', 'Basal keratinocytes': '102.5', 'Suprabasal keratinocytes': '162.6', 'Basal squamous epithelial cells': '51.0', 'Squamous epithelial cells': '106.9', 'Alveolar cells type 1': '0.437', 'Alveolar cells type 2': '0.706', 'Salivary duct cells': '95.9', 'Ductal cells': '0.541', 'Hepatocytes': '0.600', 'Cholangiocytes': '129.7', 'Proximal tubular cells': '0.042', 'Distal tubular cells': '0.0', 'Collecting duct cells': '143.9', 'Mesothelial cells': '0.799', 'Sertoli cells': '0.252', 'Granulosa cells': '12.9', 'Enteroendocrine cells': '92.4', 'Pancreatic endocrine cells': '78.1', 'Leydig cells': '0.264', 'Excitatory neurons': '0.7', 'Inhibitory neurons': '1.3', 'Cone photoreceptor cells': '0.0', 'Rod photoreceptor cells': '0.0', 'Bipolar cells': '0.2', 'Horizontal cells': '0.6', 'Astrocytes': '0.6', 'Oligodendrocyte precursor cells': '0.5', 'Oligodendrocytes': '29.9', 'Microglial cells': '0.9', 'Muller glia cells': '0.1', 'Schwann cells': '0.131', 'Spermatogonia': '0.392', 'Spermatocytes': '0.193', 'Early spermatids': '-0.217', 'Late spermatids': '-0.290', 'Oocytes': '16.9', 'Cytotrophoblasts': '119.2', 'Syncytiotrophoblasts': '45.0', 'Extravillous trophoblasts': '24.9', 'Endothelial cells': '6.1', 'Lymphatic endothelial cells': '0.4', 'Cardiomyocytes': '0.135', 'Skeletal myocytes': '0.107', 'Smooth muscle cells': '5.8', 'Adipocytes': '2.1', 'Melanocytes': '0.335', 'Fibroblasts': '6.5', 'Peritubular cells': '0.210', 'Endometrial stromal cells': '27.7', 'Ovarian stromal cells': '0.7', 'Undifferentiated cells': '101.6', 'T-cells': '2.9', 'B-cells': '4.4', 'Plasma cells': '6.1', 'Nk-cells': '0.0', 'Granulocytes': '8.4', 'Monocytes': '0.0', 'Macrophages': '6.0', 'Hofbauer cells': '4.3', 'Kupffer cells': '1.0', 'Dendritic cells': '5.9', 'Langerhans cells': '0.304', 'Erythroid cells': '0.036', 'Adipocytes (Subcutaneous)': '-0.081', 'Adipocytes (Visceral)': '-0.209', 'Breast glandular cells (progenitors)': '0.538', 'Adipocytes (Breast)': '-0.689', 'Colon enterocytes': '0.790', 'Colon enteroendocrine cells': '0.112', 'Enteric glia cells': '-0.048', 'Mitotic cells (Colon)': '0.299', 'Mitotic cells (Heart)': '0.120', 'Podocytes': '-0.118', 'Ascending Loop of Henle cells': '0.475', 'Intercalated cells': '0.212', 'Cholangiocyte': '0.090', 'NK-cells (Liver)': '-0.005', 'Respiratory ciliated cells': '-0.012', 'Mitotic cells (Lung)': '0.071', 'NK-cells (Lung)': '-0.266', 'B-cells (Lung)': '-0.296', 'Alpha cells': '0.270', 'Beta cells': '0.152', 'Prostate glandular cells': '0.764', 'Prostate basal glandular cells': '0.540', 'Urothelial cells': '0.205', 'Keratinocyte (other)': '0.510', 'Keratinocyte (granular)': '0.055', 'Hair cortex cells': '0.080', 'Inner root sheath cells': '0.131', 'Outer root sheath cells': '0.175', 'Sebaceous gland cells': '0.156', 'Eccrine sweat gland cells': '-0.207', 'Adipocytes (Skin)': '-0.244', 'Mitotic cells (Skin)': '0.442', 'Parietal cells': '0.654', 'Chief cells': '0.649', 'Gastric mucous cells': '0.781', 'Gastric enteroendocrine cells': '0.590', 'Mitotic cells (Stomach)': '0.445', 'Parafollicular cells': '0.173', 'Thyroid glandular cells': '0.865', 'Mitotic cells (Thyroid)': '-0.081', 'Adrenal cortex cells': '0.051', 'Adrenal medulla cells': '0.087', 'Mitotic cells (Adrenal gland)': '0.072', 'Minor salivary glandular cells': '0.371', 'Minor salivary gland ductal cells': '-0.142', 'Minor salivary gland basal cells': '0.582', 'Mitotic cells (Minor salivary gland)': '0.567', 'Adipocytes (Minor salivary gland)': '0.050', 'Somatotropes': '0.121', 'Lactotropes': '0.322', 'Gonadotropes': '0.330', 'Corticotropes': '0.180', 'Thyrotropes': '0.496', 'Undifferentiated cells (Pituitary gland)': '-0.108', 'Mitotic cells (Spleen)': '-0.228', 'Platelets': '-0.050', 'Erythrocytes': '-0.158', 'Hematopoietic stem cells': '-0.211', 'B-cells (Spleen)': '0.266', 'NK-cells (Spleen)': '0.309', 'Amygdala excitatory': '1.0', 'Cerebellar inhibitory': '0.9', 'Cge interneuron': '0.7', 'Deep-layer corticothalamic and 6b': '1.5', 'Deep-layer intratelencephalic': '0.7', 'Deep-layer near-projecting': '0.7', 'Eccentric medium spiny neuron': '0.6', 'Hippocampal ca1-3': '1.9', 'Hippocampal ca4': '1.2', 'Hippocampal dentate gyrus': '1.1', 'Lamp5-lhx6 and chandelier': '0.5', 'Lower rhombic lip': '0.8', 'Mammillary body': '0.6', 'Medium spiny neuron': '0.7', 'Mge interneuron': '1.7', 'Midbrain-derived inhibitory': '0.7', 'Miscellaneous': '0.9', 'Splatter': '3.8', 'Thalamic excitatory': '0.5', 'Upper rhombic lip': '0.8', 'Upper-layer intratelencephalic': '0.6', 'Astrocyte': '4.4', 'Bergmann glia': '0.2', 'Central nervous system macrophage': '0.6', 'Choroid plexus epithelial cell': '52.1', 'Committed oligodendrocyte precursor': '41.5', 'Ependymal cell': '4.8', 'Oligodendrocyte': '53.1', 'Oligodendrocyte precursor cell': '2.4', 'Endothelial cell': '0.7', 'Pericyte': '0.3', 'Vascular associated smooth muscle cell': '0.0', 'Fibroblast': '17.4', 'Leukocyte': '1.1', 'Basophil': '0.0', 'Eosinophil': '0.0', 'Neutrophil': '0.0', 'Classical monocyte': '0.0', 'Non-classical monocyte': '0.0', 'Intermediate monocyte': '0.0', 'T-reg': '2.3', 'GdT-cell': '0.0', 'MAIT T-cell': '0.0', 'Memory CD4 T-cell': '0.0', 'Naive CD4 T-cell': '0.1', 'Memory CD8 T-cell': '0.2', 'Naive CD8 T-cell': '0.3', 'Memory B-cell': '0.0', 'Naive B-cell': '0.1', 'Plasmacytoid DC': '46.6', 'Myeloid DC': '8.5', 'NK-cell': '0.1', 'Total PBMC': '0.7', 'Vd2 gdTCR': '0.0', 'Memory CD4 T-cell Th1\\/Th17': '0.1', 'Memory CD4 T-cell Th17': '0.2', 'Memory CD4 T-cell Th2': '2.9', 'Non-Vd2 gdTCR': '0.1', 'Memory CD4 T-cell Th1': '0.3', 'Memory CD4 T-cell TFH': '0.5', 'Terminal effector memory CD4 T-cell': '0.0', 'Central memory CD8 T-cell': '4.8', 'Effector memory CD8 T-cell': '0.0', 'Terminal effector memory CD8 T-cell': '0.6', 'Non-switched memory B-cell': '0.0', 'Plasmablast': '3.3', 'Switched memory B-cell': '0.0', 'Exhausted memory B-cell': '0.7', 'Progenitor cell': '2.3', 'Memory T-reg': '1.3', 'Naive CD4 T-cell activated': '0.3', 'Naive CD8 T-cell activated': '0.6', 'Naive T-reg': '0.1'} | 1O6S, 2O72, 2OMT, 2OMU, 2OMV, 2OMX, 2OMY, 2OMZ, 3FF7, 3FF8, 3L6X, 3L6Y, 4ZT1, 4ZTE, 6CXY, 6OLE, 6OLF, 6OLG, 6VEL, 7STZ, 8H62 | {'Adipose Tissue': 1.2125261088039867, 'Adrenal Gland': 0.1914223992248062, 'Bladder': 39.2033519047619, 'Blood': 1.340954264800861, 'Blood Vessel': 0.3121561692883895, 'Brain': 0.8550442199091597, 'Breast': 38.54918344226579, 'Cervix Uteri': 23.539115789473684, 'Colon': 43.41292142490372, 'Esophagus': 53.97513367404844, 'Fallopian Tube': 14.900277777777776, 'Heart': 0.119140469221835, 'Kidney': 25.040449438202245, 'Liver': 26.60802654867257, 'Lung': 35.447986366782004, 'Muscle': 0.1378936151930261, 'Nerve': 17.518468982229404, 'Ovary': 3.6515122222222223, 'Pancreas': 56.89676829268293, 'Pituitary': 24.68741660777385, 'Prostate': 61.279967346938776, 'Salivary Gland': 92.01685185185184, 'Skin': 79.77571720232172, 'Small Intestine': 71.7519320855615, 'Spleen': 10.061029045643156, 'Stomach': 58.07813805013927, 'Testis': 0.8144204986149585, 'Thyroid': 135.176797856049, 'Uterus': 1.442593943661972, 'Vagina': 86.52345512820513} | BRSK2 | MSPEGHPSRWARPRRPCICPSSLCSPREPRSGPAVGRGGAAHHRVPAGHTPGPQLLQPHLHLPQGQTWLCLQPSPAGLVKLGVHCVTCQKVAIKIVNREKLSESVLMKVEREIAILKLIEHPHVLKLHDVYENKKYLYLVLEHVSGGELFDYLVKKGRLTPKEARKFFRQIISALDFCHSHSICHRDLKPENLLLDEKNNIRIADFGMASLQVGDSLLETSCGSPHYACPEVIRGEKYDGRKADVWSCGVILFALLVGALPFDDDNLRQLLEKVKRGVFHMPHFIPPDCQSLLRGMIEVDAARRLTLEHIQKHIWYIGGKNEPEPEQPIPRKVQIRSLPSLEDIDPDVLDSMHSLGCFRDRNKLLQDLLSEEENQEKMIYFLLLDRKERYPSQEDEDLPPRNEIDPPRKRVDSPMLNRHGKRRPERKSMEVLSVTDGGSPVPARRAIEMAQHGQRSRSISGASSGLSTSPLSSPRVTPHPSPRGSPLPTPKGTPVHTPKESPAGTPNPTPPSSPSVGGVPWRARLNSIKNSFLGSPRFHRRKLQVPTPEEMSNLTPESSPELAKKSWFGNFISLEKEEQIFVVIKDKPLSSIKADIVHAFLSIPSLSHSVISQTSFRAEYKATGGPAVFQKPVKFQVDITYTEGGEAQKENGIYSVTFTLLSGPSRRFKRVVETIQAQLLSTHDPPAAQHLSDTTNCMEMMTGRLSKCDEKNGQAAQAPSTPAKRSAHGPLGDSAAAGPGPGGDAEYPTGKDTAKMGPPTARREQP | Homo sapiens | null | Not found | {} | null | {'Adipose Tissue': 1.1078286794019934, 'Adrenal Gland': 1.590517054263566, 'Bladder': 1.5991380952380951, 'Blood': 0.0983902142088267, 'Blood Vessel': 5.812490861423221, 'Brain': 46.96560900832702, 'Breast': 0.9734030501089324, 'Cervix Uteri': 3.4886631578947367, 'Colon': 3.494755327342747, 'Esophagus': 2.367677446366782, 'Fallopian Tube': 4.2613666666666665, 'Heart': 0.5245389430894309, 'Kidney': 0.4644759550561798, 'Liver': 0.1069390265486725, 'Lung': 0.70915553633218, 'Muscle': 0.2100322166874221, 'Nerve': 10.807190630048463, 'Ovary': 1.8053116666666664, 'Pancreas': 31.466067073170738, 'Pituitary': 21.962957597173144, 'Prostate': 2.429728979591837, 'Salivary Gland': 0.4094632716049383, 'Skin': 0.3155113272526257, 'Small Intestine': 2.2693465240641713, 'Spleen': 0.7963746887966805, 'Stomach': 2.0036961002785514, 'Testis': 16.159296398891968, 'Thyroid': 2.084484839203675, 'Uterus': 2.7068943661971834, 'Vagina': 2.075147435897436} | [39.93, 46.46, 52.9, 44.21, 41.4, 39.93, 35.91, 38.61, 36.44, 36.25, 34.86, 32.82, 32.01, 32.75, 31.69, 35.64, 36.35, 34.66, 33.32, 32.71, 35.01, 30.17, 37.05, 36.53, 48.19, 58.22, 64.94, 73.22, 78.33, 82.63, 85.79, 89.39, 87.89, 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0.87, 0.7, 0.97, 0.94, 0.97] | null | null | null | Component of an E-cadherin/ catenin adhesion complex composed of at least E-cadherin/CDH1, beta-catenin/CTNNB1 or gamma-catenin/JUP, and potentially alpha-catenin/CTNNA1. Forms a ternary complex composed of ADAM10, CADH1 and EPHA4, | null | null | KLRG1, SPEF1, DLGAP5, AJAP1, RAPGEF2, RAB8B, PIP5K1C, PKP2, TRPV4, CTNNB1, CAV1, DDR1, TBC1D2, CTNNA1, JUP, CTNND1, PSEN1, LIMA1, CDH1, JUP, ADAM10, CADH1 , EPHA4, | null | null | null | null | Homodimer | null | 79.91949 | 0.474025 | null | null | 866 |
P12830 | Q8NI77 | null | degron_data | CDH1 | MGPWSRSLSALLLLLQVSSWLCQEPEPCHPGFDAESYTFTVPRRHLERGRVLGRVNFEDCTGRQRTAYFSLDTRFKVGTDGVITVKRPLRFHNPQIHFLVYAWDSTYRKFSTKVTLNTVGHHHRPPPHQASVSGIQAELLTFPNSSPGLRRQKRDWVIPPISCPENEKGPFPKNLVQIKSNKDKEGKVFYSITGQGADTPPVGVFIIERETGWLKVTEPLDRERIATYTLFSHAVSSNGNAVEDPMEILITVTDQNDNKPEFTQEVFKGSVMEGALPGTSVMEVTATDADDDVNTYNAAIAYTILSQDPELPDKNMFTINRNTGVISVVTTGLDRESFPTYTLVVQAADLQGEGLSTTATAVITVTDTNDNPPIFNPTTYKGQVPENEANVVITTLKVTDADAPNTPAWEAVYTILNDDGGQFVVTTNPVNNDGILKTAKGLDFEAKQQYILHVAVTNVVPFEVSLTTSTATVTVDVLDVNEAPIFVPPEKRVEVSEDFGVGQEITSYTAQEPDTFMEQKITYRIWRDTANWLEINPDTGAISTRAELDREDFEHVKNSTYTALIIATDNGSPVATGTGTLLLILSDVNDNAPIPEPRTIFFCERNPKPQVINIIDADLPPNTSPFTAELTHGASANWTIQYNDPTQESIILKPKMALEVGDYKINLKLMDNQNKDQVTTLEVSVCDCEGAAGVCRKAQPVEAGLQIPAILGILGGILALLILILLLLLFLRRRAVVKEPLLPPEDDTRDNVYYYDEEGGGEEDQDFDLSQLHRGLDARPEVTRNDVAPTLMSVPRYLPRPANPDEIGNFIDENLKAADTDPTAPPYDSLLVFDYEGSGSEAASLSSLNSSESDKDQDYDYLNEWGNRFKKLADMYGGGEDD | Homo sapiens | Cell junction, adherens junction, Cell membrane, Endosome, Golgi apparatus, trans-Golgi network, Cytoplasm, Cell junction, desmosome | Tissue enhanced (parathyroid) | {'Ciliated cells': '119.1', 'Basal respiratory cells': '71.1', 'Club cells': '97.3', 'Ionocytes': '81.0', 'Mucus glandular cells': '155.0', 'Serous glandular cells': '67.8', 'Gastric mucus-secreting cells': '133.2', 'Proximal enterocytes': '140.9', 'Paneth cells': '125.1', 'Distal enterocytes': '307.5', 'Intestinal goblet cells': '173.5', 'Exocrine glandular cells': '-0.605', 'Basal prostatic cells': '68.3', 'Prostatic glandular cells': '186.7', 'Breast glandular cells': '0.773', 'Breast myoepithelial cells': '0.700', 'Glandular and luminal cells': '313.0', 'Secretory cells': '82.3', 'Basal keratinocytes': '102.5', 'Suprabasal keratinocytes': '162.6', 'Basal squamous epithelial cells': '51.0', 'Squamous epithelial cells': '106.9', 'Alveolar cells type 1': '0.437', 'Alveolar cells type 2': '0.706', 'Salivary duct cells': '95.9', 'Ductal cells': '0.541', 'Hepatocytes': '0.600', 'Cholangiocytes': '129.7', 'Proximal tubular cells': '0.042', 'Distal tubular cells': '0.0', 'Collecting duct cells': '143.9', 'Mesothelial cells': '0.799', 'Sertoli cells': '0.252', 'Granulosa cells': '12.9', 'Enteroendocrine cells': '92.4', 'Pancreatic endocrine cells': '78.1', 'Leydig cells': '0.264', 'Excitatory neurons': '0.7', 'Inhibitory neurons': '1.3', 'Cone photoreceptor cells': '0.0', 'Rod photoreceptor cells': '0.0', 'Bipolar cells': '0.2', 'Horizontal cells': '0.6', 'Astrocytes': '0.6', 'Oligodendrocyte precursor cells': '0.5', 'Oligodendrocytes': '29.9', 'Microglial cells': '0.9', 'Muller glia cells': '0.1', 'Schwann cells': '0.131', 'Spermatogonia': '0.392', 'Spermatocytes': '0.193', 'Early spermatids': '-0.217', 'Late spermatids': '-0.290', 'Oocytes': '16.9', 'Cytotrophoblasts': '119.2', 'Syncytiotrophoblasts': '45.0', 'Extravillous trophoblasts': '24.9', 'Endothelial cells': '6.1', 'Lymphatic endothelial cells': '0.4', 'Cardiomyocytes': '0.135', 'Skeletal myocytes': '0.107', 'Smooth muscle cells': '5.8', 'Adipocytes': '2.1', 'Melanocytes': '0.335', 'Fibroblasts': '6.5', 'Peritubular cells': '0.210', 'Endometrial stromal cells': '27.7', 'Ovarian stromal cells': '0.7', 'Undifferentiated cells': '101.6', 'T-cells': '2.9', 'B-cells': '4.4', 'Plasma cells': '6.1', 'Nk-cells': '0.0', 'Granulocytes': '8.4', 'Monocytes': '0.0', 'Macrophages': '6.0', 'Hofbauer cells': '4.3', 'Kupffer cells': '1.0', 'Dendritic cells': '5.9', 'Langerhans cells': '0.304', 'Erythroid cells': '0.036', 'Adipocytes (Subcutaneous)': '-0.081', 'Adipocytes (Visceral)': '-0.209', 'Breast glandular cells (progenitors)': '0.538', 'Adipocytes (Breast)': '-0.689', 'Colon enterocytes': '0.790', 'Colon enteroendocrine cells': '0.112', 'Enteric glia cells': '-0.048', 'Mitotic cells (Colon)': '0.299', 'Mitotic cells (Heart)': '0.120', 'Podocytes': '-0.118', 'Ascending Loop of Henle cells': '0.475', 'Intercalated cells': '0.212', 'Cholangiocyte': '0.090', 'NK-cells (Liver)': '-0.005', 'Respiratory ciliated cells': '-0.012', 'Mitotic cells (Lung)': '0.071', 'NK-cells (Lung)': '-0.266', 'B-cells (Lung)': '-0.296', 'Alpha cells': '0.270', 'Beta cells': '0.152', 'Prostate glandular cells': '0.764', 'Prostate basal glandular cells': '0.540', 'Urothelial cells': '0.205', 'Keratinocyte (other)': '0.510', 'Keratinocyte (granular)': '0.055', 'Hair cortex cells': '0.080', 'Inner root sheath cells': '0.131', 'Outer root sheath cells': '0.175', 'Sebaceous gland cells': '0.156', 'Eccrine sweat gland cells': '-0.207', 'Adipocytes (Skin)': '-0.244', 'Mitotic cells (Skin)': '0.442', 'Parietal cells': '0.654', 'Chief cells': '0.649', 'Gastric mucous cells': '0.781', 'Gastric enteroendocrine cells': '0.590', 'Mitotic cells (Stomach)': '0.445', 'Parafollicular cells': '0.173', 'Thyroid glandular cells': '0.865', 'Mitotic cells (Thyroid)': '-0.081', 'Adrenal cortex cells': '0.051', 'Adrenal medulla cells': '0.087', 'Mitotic cells (Adrenal gland)': '0.072', 'Minor salivary glandular cells': '0.371', 'Minor salivary gland ductal cells': '-0.142', 'Minor salivary gland basal cells': '0.582', 'Mitotic cells (Minor salivary gland)': '0.567', 'Adipocytes (Minor salivary gland)': '0.050', 'Somatotropes': '0.121', 'Lactotropes': '0.322', 'Gonadotropes': '0.330', 'Corticotropes': '0.180', 'Thyrotropes': '0.496', 'Undifferentiated cells (Pituitary gland)': '-0.108', 'Mitotic cells (Spleen)': '-0.228', 'Platelets': '-0.050', 'Erythrocytes': '-0.158', 'Hematopoietic stem cells': '-0.211', 'B-cells (Spleen)': '0.266', 'NK-cells (Spleen)': '0.309', 'Amygdala excitatory': '1.0', 'Cerebellar inhibitory': '0.9', 'Cge interneuron': '0.7', 'Deep-layer corticothalamic and 6b': '1.5', 'Deep-layer intratelencephalic': '0.7', 'Deep-layer near-projecting': '0.7', 'Eccentric medium spiny neuron': '0.6', 'Hippocampal ca1-3': '1.9', 'Hippocampal ca4': '1.2', 'Hippocampal dentate gyrus': '1.1', 'Lamp5-lhx6 and chandelier': '0.5', 'Lower rhombic lip': '0.8', 'Mammillary body': '0.6', 'Medium spiny neuron': '0.7', 'Mge interneuron': '1.7', 'Midbrain-derived inhibitory': '0.7', 'Miscellaneous': '0.9', 'Splatter': '3.8', 'Thalamic excitatory': '0.5', 'Upper rhombic lip': '0.8', 'Upper-layer intratelencephalic': '0.6', 'Astrocyte': '4.4', 'Bergmann glia': '0.2', 'Central nervous system macrophage': '0.6', 'Choroid plexus epithelial cell': '52.1', 'Committed oligodendrocyte precursor': '41.5', 'Ependymal cell': '4.8', 'Oligodendrocyte': '53.1', 'Oligodendrocyte precursor cell': '2.4', 'Endothelial cell': '0.7', 'Pericyte': '0.3', 'Vascular associated smooth muscle cell': '0.0', 'Fibroblast': '17.4', 'Leukocyte': '1.1', 'Basophil': '0.0', 'Eosinophil': '0.0', 'Neutrophil': '0.0', 'Classical monocyte': '0.0', 'Non-classical monocyte': '0.0', 'Intermediate monocyte': '0.0', 'T-reg': '2.3', 'GdT-cell': '0.0', 'MAIT T-cell': '0.0', 'Memory CD4 T-cell': '0.0', 'Naive CD4 T-cell': '0.1', 'Memory CD8 T-cell': '0.2', 'Naive CD8 T-cell': '0.3', 'Memory B-cell': '0.0', 'Naive B-cell': '0.1', 'Plasmacytoid DC': '46.6', 'Myeloid DC': '8.5', 'NK-cell': '0.1', 'Total PBMC': '0.7', 'Vd2 gdTCR': '0.0', 'Memory CD4 T-cell Th1\\/Th17': '0.1', 'Memory CD4 T-cell Th17': '0.2', 'Memory CD4 T-cell Th2': '2.9', 'Non-Vd2 gdTCR': '0.1', 'Memory CD4 T-cell Th1': '0.3', 'Memory CD4 T-cell TFH': '0.5', 'Terminal effector memory CD4 T-cell': '0.0', 'Central memory CD8 T-cell': '4.8', 'Effector memory CD8 T-cell': '0.0', 'Terminal effector memory CD8 T-cell': '0.6', 'Non-switched memory B-cell': '0.0', 'Plasmablast': '3.3', 'Switched memory B-cell': '0.0', 'Exhausted memory B-cell': '0.7', 'Progenitor cell': '2.3', 'Memory T-reg': '1.3', 'Naive CD4 T-cell activated': '0.3', 'Naive CD8 T-cell activated': '0.6', 'Naive T-reg': '0.1'} | 1O6S, 2O72, 2OMT, 2OMU, 2OMV, 2OMX, 2OMY, 2OMZ, 3FF7, 3FF8, 3L6X, 3L6Y, 4ZT1, 4ZTE, 6CXY, 6OLE, 6OLF, 6OLG, 6VEL, 7STZ, 8H62 | {'Adipose Tissue': 1.2125261088039867, 'Adrenal Gland': 0.1914223992248062, 'Bladder': 39.2033519047619, 'Blood': 1.340954264800861, 'Blood Vessel': 0.3121561692883895, 'Brain': 0.8550442199091597, 'Breast': 38.54918344226579, 'Cervix Uteri': 23.539115789473684, 'Colon': 43.41292142490372, 'Esophagus': 53.97513367404844, 'Fallopian Tube': 14.900277777777776, 'Heart': 0.119140469221835, 'Kidney': 25.040449438202245, 'Liver': 26.60802654867257, 'Lung': 35.447986366782004, 'Muscle': 0.1378936151930261, 'Nerve': 17.518468982229404, 'Ovary': 3.6515122222222223, 'Pancreas': 56.89676829268293, 'Pituitary': 24.68741660777385, 'Prostate': 61.279967346938776, 'Salivary Gland': 92.01685185185184, 'Skin': 79.77571720232172, 'Small Intestine': 71.7519320855615, 'Spleen': 10.061029045643156, 'Stomach': 58.07813805013927, 'Testis': 0.8144204986149585, 'Thyroid': 135.176797856049, 'Uterus': 1.442593943661972, 'Vagina': 86.52345512820513} | KIF18A | MSVTEEDLCHHMKVVVRVRPENTKEKAAGFHKVVHVVDKHILVFDPKQEEVSFFHGKKTTNQNVIKKQNKDLKFVFDAVFDETSTQSEVFEHTTKPILRSFLNGYNCTVLAYGATGAGKTHTMLGSADEPGVMYLTMLHLYKCMDEIKEEKICSTAVSYLEVYNEQIRDLLVNSGPLAVREDTQKGVVVHGLTLHQPKSSEEILHLLDNGNKNRTQHPTDMNATSSRSHAVFQIYLRQQDKTASINQNVRIAKMSLIDLAGSERASTSGAKGTRFVEGTNINRSLLALGNVINALADSKRKNQHIPYRNSKLTRLLKDSLGGNCQTIMIAAVSPSSVFYDDTYNTLKYANRAKDIKSSLKSNVLNVNNHITQYVKICNEQKAEILLLKEKLKAYEEQKAFTNENDQAKLMISNPQEKEIERFQEILNCLFQNREEIRQEYLKLEMLLKENELKSFYQQQCHKQIEMMCSEDKVEKATGKRDHRLAMLKTRRSYLEKRREEELKQFDENTNWLHRVEKEMGLLSQNGHIPKELKKDLHCHHLHLQNKDLKAQIRHMMDLACLQEQQHRQTEAVLNALLPTLRKQYCTLKEAGLSNAAFESDFKEIEHLVERKKVVVWADQTAEQPKQNDLPGISVLMTFPQLGPVQPIPCCSSSGGTNLVKIPTEKRTRRKLMPSPLKGQHTLKSPPSQSVQLNDSLSKELQPIVYTPEDCRKAFQNPSTVTLMKPSSFTTSFQAISSNINSDNCLKMLCEVAIPHNRRKECGQEDLDSTFTICEDIKSSKCKLPEQESLPNDNKDILQRLDPSSFSTKHSMPVPSMVPSYMAMTTAAKRKRKLTSSTSNSSLTADVNSGFAKRVRQDNSSEKHLQENKPTMEHKRNICKINPSMVRKFGRNISKGNLR | Homo sapiens | Cell projection, ruffle, Cytoplasm, Nucleus, Cytoplasm, cytoskeleton, microtubule organizing center, centrosome | Group enriched (bone marrow, lymphoid tissue, testis) | {'Ciliated cells': '1.9', 'Basal respiratory cells': '1.5', 'Club cells': '0.7', 'Ionocytes': '1.1', 'Mucus glandular cells': '1.2', 'Serous glandular cells': '0.1', 'Gastric mucus-secreting cells': '1.2', 'Proximal enterocytes': '0.5', 'Paneth cells': '0.1', 'Distal enterocytes': '1.3', 'Intestinal goblet cells': '2.1', 'Exocrine glandular cells': '-0.401', 'Basal prostatic cells': '0.2', 'Prostatic glandular cells': '0.1', 'Breast glandular cells': '0.457', 'Breast myoepithelial cells': '0.532', 'Glandular and luminal cells': '3.1', 'Secretory cells': '1.7', 'Basal keratinocytes': '3.3', 'Suprabasal keratinocytes': '1.3', 'Basal squamous epithelial cells': '1.8', 'Squamous epithelial cells': '4.0', 'Alveolar cells type 1': '0.103', 'Alveolar cells type 2': '0.193', 'Salivary duct cells': '1.2', 'Ductal cells': '0.405', 'Hepatocytes': '0.238', 'Cholangiocytes': '0.0', 'Proximal tubular cells': '0.095', 'Distal tubular cells': '0.0', 'Collecting duct cells': '0.0', 'Mesothelial cells': '0.254', 'Sertoli cells': '-0.379', 'Granulosa cells': '4.0', 'Enteroendocrine cells': '1.9', 'Pancreatic endocrine cells': '0.0', 'Leydig cells': '-0.364', 'Excitatory neurons': '0.2', 'Inhibitory neurons': '0.1', 'Cone photoreceptor cells': '1.7', 'Rod photoreceptor cells': '1.2', 'Bipolar cells': '0.0', 'Horizontal cells': '0.0', 'Astrocytes': '0.0', 'Oligodendrocyte precursor cells': '0.5', 'Oligodendrocytes': '0.9', 'Microglial cells': '0.9', 'Muller glia cells': '0.4', 'Schwann cells': '0.020', 'Spermatogonia': '0.022', 'Spermatocytes': '0.558', 'Early spermatids': '0.792', 'Late spermatids': '0.413', 'Oocytes': '23.5', 'Cytotrophoblasts': '4.6', 'Syncytiotrophoblasts': '1.2', 'Extravillous trophoblasts': '6.6', 'Endothelial cells': '1.0', 'Lymphatic endothelial cells': '0.4', 'Cardiomyocytes': '0.295', 'Skeletal myocytes': '0.062', 'Smooth muscle cells': '1.0', 'Adipocytes': '1.1', 'Melanocytes': '0.430', 'Fibroblasts': '1.0', 'Peritubular cells': '-0.276', 'Endometrial stromal cells': '2.1', 'Ovarian stromal cells': '1.0', 'Undifferentiated cells': '6.7', 'T-cells': '3.1', 'B-cells': '2.8', 'Plasma cells': '5.6', 'Nk-cells': '3.0', 'Granulocytes': '1.7', 'Monocytes': '0.9', 'Macrophages': '1.8', 'Hofbauer cells': '1.4', 'Kupffer cells': '2.9', 'Dendritic cells': '1.2', 'Langerhans cells': '0.229', 'Erythroid cells': '0.138', 'Adipocytes (Subcutaneous)': '-0.347', 'Adipocytes (Visceral)': '-0.191', 'Breast glandular cells (progenitors)': '0.388', 'Adipocytes (Breast)': '-0.461', 'Colon enterocytes': '0.285', 'Colon enteroendocrine cells': '0.021', 'Enteric glia cells': '0.004', 'Mitotic cells (Colon)': '0.433', 'Mitotic cells (Heart)': '0.533', 'Podocytes': '-0.198', 'Ascending Loop of Henle cells': '0.370', 'Intercalated cells': '-0.198', 'Cholangiocyte': '0.289', 'NK-cells (Liver)': '-0.027', 'Respiratory ciliated cells': '0.065', 'Mitotic cells (Lung)': '0.451', 'NK-cells (Lung)': '0.085', 'B-cells (Lung)': '0.070', 'Alpha cells': '0.167', 'Beta cells': '0.084', 'Prostate glandular cells': '-0.200', 'Prostate basal glandular cells': '0.128', 'Urothelial cells': '0.174', 'Keratinocyte (other)': '0.279', 'Keratinocyte (granular)': '-0.111', 'Hair cortex cells': '-0.031', 'Inner root sheath cells': '0.109', 'Outer root sheath cells': '0.168', 'Sebaceous gland cells': '0.082', 'Eccrine sweat gland cells': '0.005', 'Adipocytes (Skin)': '-0.151', 'Mitotic cells (Skin)': '0.843', 'Parietal cells': '0.015', 'Chief cells': '0.006', 'Gastric mucous cells': '0.452', 'Gastric enteroendocrine cells': '0.112', 'Mitotic cells (Stomach)': '0.816', 'Parafollicular cells': '0.111', 'Thyroid glandular cells': '0.370', 'Mitotic cells (Thyroid)': '0.101', 'Adrenal cortex cells': '0.371', 'Adrenal medulla cells': '0.025', 'Mitotic cells (Adrenal gland)': '0.747', 'Minor salivary glandular cells': '0.163', 'Minor salivary gland ductal cells': '-0.264', 'Minor salivary gland basal cells': '0.689', 'Mitotic cells (Minor salivary gland)': '0.874', 'Adipocytes (Minor salivary gland)': '0.187', 'Somatotropes': '-0.276', 'Lactotropes': '-0.282', 'Gonadotropes': '-0.042', 'Corticotropes': '-0.260', 'Thyrotropes': '-0.131', 'Undifferentiated cells (Pituitary gland)': '0.551', 'Mitotic cells (Spleen)': '0.859', 'Platelets': '0.027', 'Erythrocytes': '0.286', 'Hematopoietic stem cells': '0.247', 'B-cells (Spleen)': '-0.037', 'NK-cells (Spleen)': '-0.056', 'Amygdala excitatory': '0.6', 'Cerebellar inhibitory': '0.1', 'Cge interneuron': '0.1', 'Deep-layer corticothalamic and 6b': '0.2', 'Deep-layer intratelencephalic': '0.6', 'Deep-layer near-projecting': '0.1', 'Eccentric medium spiny neuron': '0.3', 'Hippocampal ca1-3': '0.4', 'Hippocampal ca4': '0.7', 'Hippocampal dentate gyrus': '2.9', 'Lamp5-lhx6 and chandelier': '0.1', 'Lower rhombic lip': '0.9', 'Mammillary body': '4.0', 'Medium spiny neuron': '0.3', 'Mge interneuron': '0.1', 'Midbrain-derived inhibitory': '0.4', 'Miscellaneous': '0.3', 'Splatter': '0.4', 'Thalamic excitatory': '0.4', 'Upper rhombic lip': '0.3', 'Upper-layer intratelencephalic': '0.3', 'Astrocyte': '1.2', 'Bergmann glia': '1.8', 'Central nervous system macrophage': '2.5', 'Choroid plexus epithelial cell': '1.6', 'Committed oligodendrocyte precursor': '0.6', 'Ependymal cell': '4.7', 'Oligodendrocyte': '2.0', 'Oligodendrocyte precursor cell': '0.9', 'Endothelial cell': '0.5', 'Pericyte': '0.3', 'Vascular associated smooth muscle cell': '7.7', 'Fibroblast': '0.4', 'Leukocyte': '4.8', 'Basophil': '1.9', 'Eosinophil': '0.3', 'Neutrophil': '0.0', 'Classical monocyte': '1.1', 'Non-classical monocyte': '0.6', 'Intermediate monocyte': '0.0', 'T-reg': '1.4', 'GdT-cell': '0.1', 'MAIT T-cell': '1.3', 'Memory CD4 T-cell': '0.4', 'Naive CD4 T-cell': '0.9', 'Memory CD8 T-cell': '0.2', 'Naive CD8 T-cell': '0.6', 'Memory B-cell': '1.0', 'Naive B-cell': '2.5', 'Plasmacytoid DC': '0.5', 'Myeloid DC': '1.3', 'NK-cell': '1.8', 'Total PBMC': '0.5', 'Vd2 gdTCR': '0.8', 'Memory CD4 T-cell Th1\\/Th17': '1.1', 'Memory CD4 T-cell Th17': '1.4', 'Memory CD4 T-cell Th2': '1.5', 'Non-Vd2 gdTCR': '0.8', 'Memory CD4 T-cell Th1': '1.1', 'Memory CD4 T-cell TFH': '0.9', 'Terminal effector memory CD4 T-cell': '1.3', 'Central memory CD8 T-cell': '0.6', 'Effector memory CD8 T-cell': '3.0', 'Terminal effector memory CD8 T-cell': '1.2', 'Non-switched memory B-cell': '2.5', 'Plasmablast': '5.7', 'Switched memory B-cell': '2.4', 'Exhausted memory B-cell': '3.2', 'Progenitor cell': '1.7', 'Memory T-reg': '2.4', 'Naive CD4 T-cell activated': '1.0', 'Naive CD8 T-cell activated': '1.2', 'Naive T-reg': '1.2'} | 3LRE, 5OAM, 5OCU, 5OGC, 7RSI | {'Adipose Tissue': 0.4104360049833886, 'Adrenal Gland': 0.2470265116279069, 'Bladder': 0.37954, 'Blood': 4.028946421959096, 'Blood Vessel': 0.5657229138576779, 'Brain': 0.1335050071915215, 'Breast': 0.4532280392156863, 'Cervix Uteri': 0.5301626315789474, 'Colon': 0.6927017098844673, 'Esophagus': 1.0244078117647055, 'Fallopian Tube': 0.4102777777777777, 'Heart': 0.0943501010452961, 'Kidney': 0.2888380898876404, 'Liver': 0.1270377389380531, 'Lung': 1.380150034602076, 'Muscle': 0.1946960896637609, 'Nerve': 0.3874349596122778, 'Ovary': 0.5054153888888888, 'Pancreas': 0.1211120579268292, 'Pituitary': 0.3888806360424028, 'Prostate': 0.4077087346938775, 'Salivary Gland': 0.5695219753086419, 'Skin': 4.582113001658374, 'Small Intestine': 1.2864200534759358, 'Spleen': 1.3268427385892116, 'Stomach': 0.5775858217270194, 'Testis': 19.19371191135734, 'Thyroid': 1.6251788667687597, 'Uterus': 0.4364119014084507, 'Vagina': 1.2061108974358974} | [39.93, 46.46, 52.9, 44.21, 41.4, 39.93, 35.91, 38.61, 36.44, 36.25, 34.86, 32.82, 32.01, 32.75, 31.69, 35.64, 36.35, 34.66, 33.32, 32.71, 35.01, 30.17, 37.05, 36.53, 48.19, 58.22, 64.94, 73.22, 78.33, 82.63, 85.79, 89.39, 87.89, 85.58, 83.93, 89.1, 89.27, 90.66, 87.86, 86.2, 82.97, 72.75, 73.3, 76.44, 82.38, 82.41, 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0.88, 0.94, 0.99, 0.95, 0.95, 0.99, 0.94, 0.96, 0.99, 0.93, 0.98, 0.96, 0.93, 0.88, 0.96, 0.91, 0.98, 0.92, 1.0, 0.98, 1.0, 1.0, 1.0, 1.0, 0.99, 0.97, 0.99, 0.92, 0.97, 0.86, 0.93, 0.92, 0.86, 0.71, 0.79, 0.72, 0.77, 0.85, 0.91, 0.86, 0.9, 0.83, 0.92, 0.82, 0.82, 0.84, 0.69, 0.95, 0.92, 0.91, 0.97, 0.86, 0.97, 0.88, 0.94, 0.95, 0.92, 0.94, 0.89, 0.99, 0.88, 0.99, 0.96, 1.0, 0.97, 0.99, 1.0, 1.0, 1.0, 0.99, 1.0, 0.99, 1.0, 0.98, 0.99, 0.99, 0.97, 0.98, 0.98, 0.87, 0.88, 0.82, 0.82, 0.89, 0.85, 0.89, 0.89, 0.84, 0.8, 0.91, 0.77, 0.87, 0.89, 0.89, 0.95, 0.94, 0.93, 0.97, 0.97, 0.98, 0.99, 0.91, 0.95, 0.98, 0.92, 0.96, 0.83, 0.89, 0.73, 0.91, 0.76, 0.94, 0.88, 0.97, 0.96, 0.96, 0.97, 0.99, 1.0, 1.0, 1.0, 0.99, 0.83, 0.99, 0.87, 1.0, 1.0, 1.0, 0.98, 1.0, 0.97, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 0.49, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 0.97, 1.0, 0.99, 1.0, 0.98, 0.94, 0.97, 0.84, 0.99, 0.89, 0.97, 0.64, 0.62, 0.61, 0.72, 0.41, 0.55, 0.2, 0.51, 0.51, 0.6, 0.72, 0.85, 0.93, 0.92, 0.92, 1.0, 0.93, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 0.99, 1.0, 0.99, 0.99, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 0.99, 1.0, 0.97, 1.0, 1.0, 1.0, 1.0, 0.99, 1.0, 1.0, 1.0, 0.96, 1.0, 0.94, 1.0, 0.98, 0.96, 0.97, 0.84, 0.93, 0.83, 0.93, 0.91, 1.0, 1.0, 0.93, 0.94, 0.94, 0.96, 1.0, 1.0, 0.99, 1.0, 0.99, 1.0, 1.0, 1.0, 0.99, 0.98, 1.0, 0.98, 1.0, 1.0, 1.0, 1.0, 1.0, 0.99] | null | Component of an E-cadherin/ catenin adhesion complex composed of at least E-cadherin/CDH1, beta-catenin/CTNNB1 or gamma-catenin/JUP, and potentially alpha-catenin/CTNNA1. Forms a ternary complex composed of ADAM10, CADH1 and EPHA4, | null | null | KLRG1, SPEF1, DLGAP5, AJAP1, RAPGEF2, RAB8B, PIP5K1C, PKP2, TRPV4, CTNNB1, CAV1, DDR1, TBC1D2, CTNNA1, JUP, CTNND1, PSEN1, LIMA1, CDH1, JUP, ADAM10, CADH1 , EPHA4, | null | null | null | null | Homodimer | null | 79.91949 | 0.474025 | 67.126537 | 0.548218 | 650 |
P12830 | Q8WWK9 | null | degron_data | CDH1 | MGPWSRSLSALLLLLQVSSWLCQEPEPCHPGFDAESYTFTVPRRHLERGRVLGRVNFEDCTGRQRTAYFSLDTRFKVGTDGVITVKRPLRFHNPQIHFLVYAWDSTYRKFSTKVTLNTVGHHHRPPPHQASVSGIQAELLTFPNSSPGLRRQKRDWVIPPISCPENEKGPFPKNLVQIKSNKDKEGKVFYSITGQGADTPPVGVFIIERETGWLKVTEPLDRERIATYTLFSHAVSSNGNAVEDPMEILITVTDQNDNKPEFTQEVFKGSVMEGALPGTSVMEVTATDADDDVNTYNAAIAYTILSQDPELPDKNMFTINRNTGVISVVTTGLDRESFPTYTLVVQAADLQGEGLSTTATAVITVTDTNDNPPIFNPTTYKGQVPENEANVVITTLKVTDADAPNTPAWEAVYTILNDDGGQFVVTTNPVNNDGILKTAKGLDFEAKQQYILHVAVTNVVPFEVSLTTSTATVTVDVLDVNEAPIFVPPEKRVEVSEDFGVGQEITSYTAQEPDTFMEQKITYRIWRDTANWLEINPDTGAISTRAELDREDFEHVKNSTYTALIIATDNGSPVATGTGTLLLILSDVNDNAPIPEPRTIFFCERNPKPQVINIIDADLPPNTSPFTAELTHGASANWTIQYNDPTQESIILKPKMALEVGDYKINLKLMDNQNKDQVTTLEVSVCDCEGAAGVCRKAQPVEAGLQIPAILGILGGILALLILILLLLLFLRRRAVVKEPLLPPEDDTRDNVYYYDEEGGGEEDQDFDLSQLHRGLDARPEVTRNDVAPTLMSVPRYLPRPANPDEIGNFIDENLKAADTDPTAPPYDSLLVFDYEGSGSEAASLSSLNSSESDKDQDYDYLNEWGNRFKKLADMYGGGEDD | Homo sapiens | Cell junction, adherens junction, Cell membrane, Endosome, Golgi apparatus, trans-Golgi network, Cytoplasm, Cell junction, desmosome | Tissue enhanced (parathyroid) | {'Ciliated cells': '119.1', 'Basal respiratory cells': '71.1', 'Club cells': '97.3', 'Ionocytes': '81.0', 'Mucus glandular cells': '155.0', 'Serous glandular cells': '67.8', 'Gastric mucus-secreting cells': '133.2', 'Proximal enterocytes': '140.9', 'Paneth cells': '125.1', 'Distal enterocytes': '307.5', 'Intestinal goblet cells': '173.5', 'Exocrine glandular cells': '-0.605', 'Basal prostatic cells': '68.3', 'Prostatic glandular cells': '186.7', 'Breast glandular cells': '0.773', 'Breast myoepithelial cells': '0.700', 'Glandular and luminal cells': '313.0', 'Secretory cells': '82.3', 'Basal keratinocytes': '102.5', 'Suprabasal keratinocytes': '162.6', 'Basal squamous epithelial cells': '51.0', 'Squamous epithelial cells': '106.9', 'Alveolar cells type 1': '0.437', 'Alveolar cells type 2': '0.706', 'Salivary duct cells': '95.9', 'Ductal cells': '0.541', 'Hepatocytes': '0.600', 'Cholangiocytes': '129.7', 'Proximal tubular cells': '0.042', 'Distal tubular cells': '0.0', 'Collecting duct cells': '143.9', 'Mesothelial cells': '0.799', 'Sertoli cells': '0.252', 'Granulosa cells': '12.9', 'Enteroendocrine cells': '92.4', 'Pancreatic endocrine cells': '78.1', 'Leydig cells': '0.264', 'Excitatory neurons': '0.7', 'Inhibitory neurons': '1.3', 'Cone photoreceptor cells': '0.0', 'Rod photoreceptor cells': '0.0', 'Bipolar cells': '0.2', 'Horizontal cells': '0.6', 'Astrocytes': '0.6', 'Oligodendrocyte precursor cells': '0.5', 'Oligodendrocytes': '29.9', 'Microglial cells': '0.9', 'Muller glia cells': '0.1', 'Schwann cells': '0.131', 'Spermatogonia': '0.392', 'Spermatocytes': '0.193', 'Early spermatids': '-0.217', 'Late spermatids': '-0.290', 'Oocytes': '16.9', 'Cytotrophoblasts': '119.2', 'Syncytiotrophoblasts': '45.0', 'Extravillous trophoblasts': '24.9', 'Endothelial cells': '6.1', 'Lymphatic endothelial cells': '0.4', 'Cardiomyocytes': '0.135', 'Skeletal myocytes': '0.107', 'Smooth muscle cells': '5.8', 'Adipocytes': '2.1', 'Melanocytes': '0.335', 'Fibroblasts': '6.5', 'Peritubular cells': '0.210', 'Endometrial stromal cells': '27.7', 'Ovarian stromal cells': '0.7', 'Undifferentiated cells': '101.6', 'T-cells': '2.9', 'B-cells': '4.4', 'Plasma cells': '6.1', 'Nk-cells': '0.0', 'Granulocytes': '8.4', 'Monocytes': '0.0', 'Macrophages': '6.0', 'Hofbauer cells': '4.3', 'Kupffer cells': '1.0', 'Dendritic cells': '5.9', 'Langerhans cells': '0.304', 'Erythroid cells': '0.036', 'Adipocytes (Subcutaneous)': '-0.081', 'Adipocytes (Visceral)': '-0.209', 'Breast glandular cells (progenitors)': '0.538', 'Adipocytes (Breast)': '-0.689', 'Colon enterocytes': '0.790', 'Colon enteroendocrine cells': '0.112', 'Enteric glia cells': '-0.048', 'Mitotic cells (Colon)': '0.299', 'Mitotic cells (Heart)': '0.120', 'Podocytes': '-0.118', 'Ascending Loop of Henle cells': '0.475', 'Intercalated cells': '0.212', 'Cholangiocyte': '0.090', 'NK-cells (Liver)': '-0.005', 'Respiratory ciliated cells': '-0.012', 'Mitotic cells (Lung)': '0.071', 'NK-cells (Lung)': '-0.266', 'B-cells (Lung)': '-0.296', 'Alpha cells': '0.270', 'Beta cells': '0.152', 'Prostate glandular cells': '0.764', 'Prostate basal glandular cells': '0.540', 'Urothelial cells': '0.205', 'Keratinocyte (other)': '0.510', 'Keratinocyte (granular)': '0.055', 'Hair cortex cells': '0.080', 'Inner root sheath cells': '0.131', 'Outer root sheath cells': '0.175', 'Sebaceous gland cells': '0.156', 'Eccrine sweat gland cells': '-0.207', 'Adipocytes (Skin)': '-0.244', 'Mitotic cells (Skin)': '0.442', 'Parietal cells': '0.654', 'Chief cells': '0.649', 'Gastric mucous cells': '0.781', 'Gastric enteroendocrine cells': '0.590', 'Mitotic cells (Stomach)': '0.445', 'Parafollicular cells': '0.173', 'Thyroid glandular cells': '0.865', 'Mitotic cells (Thyroid)': '-0.081', 'Adrenal cortex cells': '0.051', 'Adrenal medulla cells': '0.087', 'Mitotic cells (Adrenal gland)': '0.072', 'Minor salivary glandular cells': '0.371', 'Minor salivary gland ductal cells': '-0.142', 'Minor salivary gland basal cells': '0.582', 'Mitotic cells (Minor salivary gland)': '0.567', 'Adipocytes (Minor salivary gland)': '0.050', 'Somatotropes': '0.121', 'Lactotropes': '0.322', 'Gonadotropes': '0.330', 'Corticotropes': '0.180', 'Thyrotropes': '0.496', 'Undifferentiated cells (Pituitary gland)': '-0.108', 'Mitotic cells (Spleen)': '-0.228', 'Platelets': '-0.050', 'Erythrocytes': '-0.158', 'Hematopoietic stem cells': '-0.211', 'B-cells (Spleen)': '0.266', 'NK-cells (Spleen)': '0.309', 'Amygdala excitatory': '1.0', 'Cerebellar inhibitory': '0.9', 'Cge interneuron': '0.7', 'Deep-layer corticothalamic and 6b': '1.5', 'Deep-layer intratelencephalic': '0.7', 'Deep-layer near-projecting': '0.7', 'Eccentric medium spiny neuron': '0.6', 'Hippocampal ca1-3': '1.9', 'Hippocampal ca4': '1.2', 'Hippocampal dentate gyrus': '1.1', 'Lamp5-lhx6 and chandelier': '0.5', 'Lower rhombic lip': '0.8', 'Mammillary body': '0.6', 'Medium spiny neuron': '0.7', 'Mge interneuron': '1.7', 'Midbrain-derived inhibitory': '0.7', 'Miscellaneous': '0.9', 'Splatter': '3.8', 'Thalamic excitatory': '0.5', 'Upper rhombic lip': '0.8', 'Upper-layer intratelencephalic': '0.6', 'Astrocyte': '4.4', 'Bergmann glia': '0.2', 'Central nervous system macrophage': '0.6', 'Choroid plexus epithelial cell': '52.1', 'Committed oligodendrocyte precursor': '41.5', 'Ependymal cell': '4.8', 'Oligodendrocyte': '53.1', 'Oligodendrocyte precursor cell': '2.4', 'Endothelial cell': '0.7', 'Pericyte': '0.3', 'Vascular associated smooth muscle cell': '0.0', 'Fibroblast': '17.4', 'Leukocyte': '1.1', 'Basophil': '0.0', 'Eosinophil': '0.0', 'Neutrophil': '0.0', 'Classical monocyte': '0.0', 'Non-classical monocyte': '0.0', 'Intermediate monocyte': '0.0', 'T-reg': '2.3', 'GdT-cell': '0.0', 'MAIT T-cell': '0.0', 'Memory CD4 T-cell': '0.0', 'Naive CD4 T-cell': '0.1', 'Memory CD8 T-cell': '0.2', 'Naive CD8 T-cell': '0.3', 'Memory B-cell': '0.0', 'Naive B-cell': '0.1', 'Plasmacytoid DC': '46.6', 'Myeloid DC': '8.5', 'NK-cell': '0.1', 'Total PBMC': '0.7', 'Vd2 gdTCR': '0.0', 'Memory CD4 T-cell Th1\\/Th17': '0.1', 'Memory CD4 T-cell Th17': '0.2', 'Memory CD4 T-cell Th2': '2.9', 'Non-Vd2 gdTCR': '0.1', 'Memory CD4 T-cell Th1': '0.3', 'Memory CD4 T-cell TFH': '0.5', 'Terminal effector memory CD4 T-cell': '0.0', 'Central memory CD8 T-cell': '4.8', 'Effector memory CD8 T-cell': '0.0', 'Terminal effector memory CD8 T-cell': '0.6', 'Non-switched memory B-cell': '0.0', 'Plasmablast': '3.3', 'Switched memory B-cell': '0.0', 'Exhausted memory B-cell': '0.7', 'Progenitor cell': '2.3', 'Memory T-reg': '1.3', 'Naive CD4 T-cell activated': '0.3', 'Naive CD8 T-cell activated': '0.6', 'Naive T-reg': '0.1'} | 1O6S, 2O72, 2OMT, 2OMU, 2OMV, 2OMX, 2OMY, 2OMZ, 3FF7, 3FF8, 3L6X, 3L6Y, 4ZT1, 4ZTE, 6CXY, 6OLE, 6OLF, 6OLG, 6VEL, 7STZ, 8H62 | {'Adipose Tissue': 1.2125261088039867, 'Adrenal Gland': 0.1914223992248062, 'Bladder': 39.2033519047619, 'Blood': 1.340954264800861, 'Blood Vessel': 0.3121561692883895, 'Brain': 0.8550442199091597, 'Breast': 38.54918344226579, 'Cervix Uteri': 23.539115789473684, 'Colon': 43.41292142490372, 'Esophagus': 53.97513367404844, 'Fallopian Tube': 14.900277777777776, 'Heart': 0.119140469221835, 'Kidney': 25.040449438202245, 'Liver': 26.60802654867257, 'Lung': 35.447986366782004, 'Muscle': 0.1378936151930261, 'Nerve': 17.518468982229404, 'Ovary': 3.6515122222222223, 'Pancreas': 56.89676829268293, 'Pituitary': 24.68741660777385, 'Prostate': 61.279967346938776, 'Salivary Gland': 92.01685185185184, 'Skin': 79.77571720232172, 'Small Intestine': 71.7519320855615, 'Spleen': 10.061029045643156, 'Stomach': 58.07813805013927, 'Testis': 0.8144204986149585, 'Thyroid': 135.176797856049, 'Uterus': 1.442593943661972, 'Vagina': 86.52345512820513} | CKAP2 | MSTPAVPQDLQLPPSQRAQSAFKEQRRQKLKEHLLRRKTLFAYKQENEMLSSSRDQRVVTSEDQVQEGTKVLKLKTKMADKENMKRPAESKNNTVVGKHCIPLKPSNELTNSTVVIDTHKPKDSNQTPHLLLTEDDPQSQHMTLSQAFHLKNNSKKKQMTTEKQKQDANMPKKPVLGSYRGQIVQSKINSFRKPLQVKDESSAATKKLSATIPKATKPQPVNTSSVTVKSNRSSNMTATTKFVSTTSQNTQLVRPPIRSHHSNTRDTVKQGISRTSANVTIRKGPHEKELLQSKTALSSVKTSSSQGIIRNKTLSRSIASEVIARPASLSNDKLMEKSEPVDQRRHTAGKAIVDSRSAQPKETSEERKARLSEWKAGKGRVLKRPPNSVVTQHEPAGQNEKPVGSFWTTMAEEDEQRLFTEKVNNTFSECLNLINEGCPKEDILVTLNDLIKNIPDAKKLVKYWICLALIEPITSPIENIIAIYEKAILAGAQPIEEMRHTIVDILTMKSQEKANLGENMEKSCASKEEVKEVSIEDTGVDVDPEKLEMESKLHRNLLFQDCEKEQDNKTKDPTHDVKTPNTETRTSCLIKYNVSTTPYLQSVKKKVQFDGTNSAFKELKFLTPVRRSRRLQEKTSKLPDMLKDHYPCVSSLEQLTELGRETDAFVCRPNAALCRVYYEADTT | Homo sapiens | Cytoplasm, cytoskeleton, Cytoplasm, cytoskeleton, spindle, Cytoplasm, cytoskeleton, spindle pole | Tissue enhanced (bone) | {'Ciliated cells': '7.3', 'Basal respiratory cells': '31.1', 'Club cells': '8.9', 'Ionocytes': '8.1', 'Mucus glandular cells': '7.4', 'Serous glandular cells': '11.9', 'Gastric mucus-secreting cells': '10.6', 'Proximal enterocytes': '5.4', 'Paneth cells': '5.5', 'Distal enterocytes': '4.5', 'Intestinal goblet cells': '10.9', 'Exocrine glandular cells': '-0.217', 'Basal prostatic cells': '3.2', 'Prostatic glandular cells': '4.9', 'Breast glandular cells': '0.050', 'Breast myoepithelial cells': '-0.043', 'Glandular and luminal cells': '10.8', 'Secretory cells': '5.5', 'Basal keratinocytes': '30.8', 'Suprabasal keratinocytes': '23.2', 'Basal squamous epithelial cells': '25.5', 'Squamous epithelial cells': '40.3', 'Alveolar cells type 1': '-0.048', 'Alveolar cells type 2': '0.144', 'Salivary duct cells': '14.8', 'Ductal cells': '0.389', 'Hepatocytes': '0.437', 'Cholangiocytes': '3.8', 'Proximal tubular cells': '0.325', 'Distal tubular cells': '9.2', 'Collecting duct cells': '1.9', 'Mesothelial cells': '0.078', 'Sertoli cells': '0.065', 'Granulosa cells': '39.1', 'Enteroendocrine cells': '6.9', 'Pancreatic endocrine cells': '6.8', 'Leydig cells': '0.064', 'Excitatory neurons': '10.0', 'Inhibitory neurons': '11.9', 'Cone photoreceptor cells': '8.5', 'Rod photoreceptor cells': '6.0', 'Bipolar cells': '13.3', 'Horizontal cells': '6.3', 'Astrocytes': '5.0', 'Oligodendrocyte precursor cells': '3.3', 'Oligodendrocytes': '1.9', 'Microglial cells': '6.3', 'Muller glia cells': '11.0', 'Schwann cells': '0.139', 'Spermatogonia': '0.504', 'Spermatocytes': '0.871', 'Early spermatids': '0.400', 'Late spermatids': '-0.047', 'Oocytes': '50.7', 'Cytotrophoblasts': '44.8', 'Syncytiotrophoblasts': '11.1', 'Extravillous trophoblasts': '38.2', 'Endothelial cells': '11.1', 'Lymphatic endothelial cells': '15.9', 'Cardiomyocytes': '0.620', 'Skeletal myocytes': '0.065', 'Smooth muscle cells': '7.7', 'Adipocytes': '7.5', 'Melanocytes': '0.527', 'Fibroblasts': '9.9', 'Peritubular cells': '-0.015', 'Endometrial stromal cells': '15.2', 'Ovarian stromal cells': '6.4', 'Undifferentiated cells': '33.2', 'T-cells': '27.9', 'B-cells': '32.6', 'Plasma cells': '32.5', 'Nk-cells': '16.9', 'Granulocytes': '12.8', 'Monocytes': '15.2', 'Macrophages': '19.3', 'Hofbauer cells': '25.5', 'Kupffer cells': '19.6', 'Dendritic cells': '31.5', 'Langerhans cells': '0.286', 'Erythroid cells': '0.006', 'Adipocytes (Subcutaneous)': '0.153', 'Adipocytes (Visceral)': '0.014', 'Breast glandular cells (progenitors)': '0.113', 'Adipocytes (Breast)': '0.151', 'Colon enterocytes': '0.150', 'Colon enteroendocrine cells': '0.052', 'Enteric glia cells': '-0.196', 'Mitotic cells (Colon)': '0.287', 'Mitotic cells (Heart)': '0.530', 'Podocytes': '-0.090', 'Ascending Loop of Henle cells': '0.414', 'Intercalated cells': '0.038', 'Cholangiocyte': '0.272', 'NK-cells (Liver)': '-0.079', 'Respiratory ciliated cells': '0.030', 'Mitotic cells (Lung)': '0.635', 'NK-cells (Lung)': '-0.042', 'B-cells (Lung)': '-0.028', 'Alpha cells': '0.293', 'Beta cells': '0.121', 'Prostate glandular cells': '0.036', 'Prostate basal glandular cells': '0.298', 'Urothelial cells': '0.203', 'Keratinocyte 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0.23, 0.72, 0.79, 0.18, 0.66, 0.56, 0.01, 0.44, 0.52, 0.36, 0.01, 0.27, 0.16, 0.05, 0.1, 0.0, 0.19, 0.01, 0.32, 0.12, 0.25, 0.45, 0.29, 0.75, 0.24, 0.55, 0.4, 0.68, 0.39, 0.03, 0.49, 0.26, 0.1, 0.18, 0.53, 0.52, 0.0, 0.52, 0.83, 0.27, 0.53, 0.03, 0.63, 0.42, 0.18, 0.59, 0.46, 0.0, 0.56, 0.64, 0.13, 0.16, 0.56, 0.55, 0.05, 0.4, 0.5, 0.47, 0.08, 0.57, 0.63, 0.34, 0.59, 0.61, 0.59, 0.65, 0.7, 0.91, 0.81, 0.91, 0.96, 0.99, 1.0, 0.9, 1.0, 0.87, 0.99, 0.99, 0.99, 1.0, 0.99, 0.93, 0.96, 0.78, 0.96, 0.93, 0.94, 0.97, 0.87, 0.96, 0.95, 0.97, 0.86, 0.98, 0.96, 0.9, 1.0, 0.88, 0.97, 0.75, 0.96, 0.74, 0.97, 0.79, 0.91, 0.74, 0.8, 0.9, 0.85, 0.9, 0.94, 0.88, 0.97, 0.96, 1.0, 0.99, 0.95, 0.99, 0.96, 0.96, 0.96, 0.81, 0.89, 0.72, 0.9, 0.7, 0.79, 0.85, 0.22, 0.3, 0.71, 0.79, 0.6, 0.68, 0.99, 0.31, 0.71, 0.23, 0.28, 0.31, 0.1, 0.23, 0.18, 0.08, 0.14, 0.3, 0.33, 0.69, 0.7, 0.04, 0.54, 0.49, 0.3, 0.18, 0.75, 0.8, 0.68, 0.45, 0.87, 0.83, 0.97, 0.95, 0.87, 0.52, 0.84, 0.27, 0.55, 0.34, 0.14, 0.1, 0.17, 0.09, 0.2, 0.12, 0.31, 0.71, 0.19, 0.4, 0.38, 0.76, 0.63, 0.35, 0.61, 0.57, 0.27, 0.79, 0.86, 0.4, 0.65, 0.65, 0.9, 0.66, 0.36, 0.57, 0.84, 0.48, 0.42, 0.24, 0.04, 0.24, 0.21, 0.74, 0.68, 0.35, 0.11, 0.52, 0.8, 0.4, 0.22, 0.66, 0.82, 0.46, 0.16, 0.22, 0.32, 0.36, 0.68, 0.6, 0.86, 0.28, 0.73, 0.85, 0.16, 0.68, 0.93, 0.81, 0.78, 0.97, 0.94, 0.85, 0.99, 0.97, 0.99] | null | Component of an E-cadherin/ catenin adhesion complex composed of at least E-cadherin/CDH1, beta-catenin/CTNNB1 or gamma-catenin/JUP, and potentially alpha-catenin/CTNNA1. Forms a ternary complex composed of ADAM10, CADH1 and EPHA4, | null | null | KLRG1, SPEF1, DLGAP5, AJAP1, RAPGEF2, RAB8B, PIP5K1C, PKP2, TRPV4, CTNNB1, CAV1, DDR1, TBC1D2, CTNNA1, JUP, CTNND1, PSEN1, LIMA1, CDH1, JUP, ADAM10, CADH1 , EPHA4, | null | null | null | null | Homodimer | null | 79.91949 | 0.474025 | 59.060937 | 0.738302 | 1,063 |
P12830 | Q8WWK9-4 | null | degron_data | CDH1 | MGPWSRSLSALLLLLQVSSWLCQEPEPCHPGFDAESYTFTVPRRHLERGRVLGRVNFEDCTGRQRTAYFSLDTRFKVGTDGVITVKRPLRFHNPQIHFLVYAWDSTYRKFSTKVTLNTVGHHHRPPPHQASVSGIQAELLTFPNSSPGLRRQKRDWVIPPISCPENEKGPFPKNLVQIKSNKDKEGKVFYSITGQGADTPPVGVFIIERETGWLKVTEPLDRERIATYTLFSHAVSSNGNAVEDPMEILITVTDQNDNKPEFTQEVFKGSVMEGALPGTSVMEVTATDADDDVNTYNAAIAYTILSQDPELPDKNMFTINRNTGVISVVTTGLDRESFPTYTLVVQAADLQGEGLSTTATAVITVTDTNDNPPIFNPTTYKGQVPENEANVVITTLKVTDADAPNTPAWEAVYTILNDDGGQFVVTTNPVNNDGILKTAKGLDFEAKQQYILHVAVTNVVPFEVSLTTSTATVTVDVLDVNEAPIFVPPEKRVEVSEDFGVGQEITSYTAQEPDTFMEQKITYRIWRDTANWLEINPDTGAISTRAELDREDFEHVKNSTYTALIIATDNGSPVATGTGTLLLILSDVNDNAPIPEPRTIFFCERNPKPQVINIIDADLPPNTSPFTAELTHGASANWTIQYNDPTQESIILKPKMALEVGDYKINLKLMDNQNKDQVTTLEVSVCDCEGAAGVCRKAQPVEAGLQIPAILGILGGILALLILILLLLLFLRRRAVVKEPLLPPEDDTRDNVYYYDEEGGGEEDQDFDLSQLHRGLDARPEVTRNDVAPTLMSVPRYLPRPANPDEIGNFIDENLKAADTDPTAPPYDSLLVFDYEGSGSEAASLSSLNSSESDKDQDYDYLNEWGNRFKKLADMYGGGEDD | Homo sapiens | Cell junction, adherens junction, Cell membrane, Endosome, Golgi apparatus, trans-Golgi network, Cytoplasm, Cell junction, desmosome | Tissue enhanced (parathyroid) | {'Ciliated cells': '119.1', 'Basal respiratory cells': '71.1', 'Club cells': '97.3', 'Ionocytes': '81.0', 'Mucus glandular cells': '155.0', 'Serous glandular cells': '67.8', 'Gastric mucus-secreting cells': '133.2', 'Proximal enterocytes': '140.9', 'Paneth cells': '125.1', 'Distal enterocytes': '307.5', 'Intestinal goblet cells': '173.5', 'Exocrine glandular cells': '-0.605', 'Basal prostatic cells': '68.3', 'Prostatic glandular cells': '186.7', 'Breast glandular cells': '0.773', 'Breast myoepithelial cells': '0.700', 'Glandular and luminal cells': '313.0', 'Secretory cells': '82.3', 'Basal keratinocytes': '102.5', 'Suprabasal keratinocytes': '162.6', 'Basal squamous epithelial cells': '51.0', 'Squamous epithelial cells': '106.9', 'Alveolar cells type 1': '0.437', 'Alveolar cells type 2': '0.706', 'Salivary duct cells': '95.9', 'Ductal cells': '0.541', 'Hepatocytes': '0.600', 'Cholangiocytes': '129.7', 'Proximal tubular cells': '0.042', 'Distal tubular cells': '0.0', 'Collecting duct cells': '143.9', 'Mesothelial cells': '0.799', 'Sertoli cells': '0.252', 'Granulosa cells': '12.9', 'Enteroendocrine cells': '92.4', 'Pancreatic endocrine cells': '78.1', 'Leydig cells': '0.264', 'Excitatory neurons': '0.7', 'Inhibitory neurons': '1.3', 'Cone photoreceptor cells': '0.0', 'Rod photoreceptor cells': '0.0', 'Bipolar cells': '0.2', 'Horizontal cells': '0.6', 'Astrocytes': '0.6', 'Oligodendrocyte precursor cells': '0.5', 'Oligodendrocytes': '29.9', 'Microglial cells': '0.9', 'Muller glia cells': '0.1', 'Schwann cells': '0.131', 'Spermatogonia': '0.392', 'Spermatocytes': '0.193', 'Early spermatids': '-0.217', 'Late spermatids': '-0.290', 'Oocytes': '16.9', 'Cytotrophoblasts': '119.2', 'Syncytiotrophoblasts': '45.0', 'Extravillous trophoblasts': '24.9', 'Endothelial cells': '6.1', 'Lymphatic endothelial cells': '0.4', 'Cardiomyocytes': '0.135', 'Skeletal myocytes': '0.107', 'Smooth muscle cells': '5.8', 'Adipocytes': '2.1', 'Melanocytes': '0.335', 'Fibroblasts': '6.5', 'Peritubular cells': '0.210', 'Endometrial stromal cells': '27.7', 'Ovarian stromal cells': '0.7', 'Undifferentiated cells': '101.6', 'T-cells': '2.9', 'B-cells': '4.4', 'Plasma cells': '6.1', 'Nk-cells': '0.0', 'Granulocytes': '8.4', 'Monocytes': '0.0', 'Macrophages': '6.0', 'Hofbauer cells': '4.3', 'Kupffer cells': '1.0', 'Dendritic cells': '5.9', 'Langerhans cells': '0.304', 'Erythroid cells': '0.036', 'Adipocytes (Subcutaneous)': '-0.081', 'Adipocytes (Visceral)': '-0.209', 'Breast glandular cells (progenitors)': '0.538', 'Adipocytes (Breast)': '-0.689', 'Colon enterocytes': '0.790', 'Colon enteroendocrine cells': '0.112', 'Enteric glia cells': '-0.048', 'Mitotic cells (Colon)': '0.299', 'Mitotic cells (Heart)': '0.120', 'Podocytes': '-0.118', 'Ascending Loop of Henle cells': '0.475', 'Intercalated cells': '0.212', 'Cholangiocyte': '0.090', 'NK-cells (Liver)': '-0.005', 'Respiratory ciliated cells': '-0.012', 'Mitotic cells (Lung)': '0.071', 'NK-cells (Lung)': '-0.266', 'B-cells (Lung)': '-0.296', 'Alpha cells': '0.270', 'Beta cells': '0.152', 'Prostate glandular cells': '0.764', 'Prostate basal glandular cells': '0.540', 'Urothelial cells': '0.205', 'Keratinocyte (other)': '0.510', 'Keratinocyte (granular)': '0.055', 'Hair cortex cells': '0.080', 'Inner root sheath cells': '0.131', 'Outer root sheath cells': '0.175', 'Sebaceous gland cells': '0.156', 'Eccrine sweat gland cells': '-0.207', 'Adipocytes (Skin)': '-0.244', 'Mitotic cells (Skin)': '0.442', 'Parietal cells': '0.654', 'Chief cells': '0.649', 'Gastric mucous cells': '0.781', 'Gastric enteroendocrine cells': '0.590', 'Mitotic cells (Stomach)': '0.445', 'Parafollicular cells': '0.173', 'Thyroid glandular cells': '0.865', 'Mitotic cells (Thyroid)': '-0.081', 'Adrenal cortex cells': '0.051', 'Adrenal medulla cells': '0.087', 'Mitotic cells (Adrenal gland)': '0.072', 'Minor salivary glandular cells': '0.371', 'Minor salivary gland ductal cells': '-0.142', 'Minor salivary gland basal cells': '0.582', 'Mitotic cells (Minor salivary gland)': '0.567', 'Adipocytes (Minor salivary gland)': '0.050', 'Somatotropes': '0.121', 'Lactotropes': '0.322', 'Gonadotropes': '0.330', 'Corticotropes': '0.180', 'Thyrotropes': '0.496', 'Undifferentiated cells (Pituitary gland)': '-0.108', 'Mitotic cells (Spleen)': '-0.228', 'Platelets': '-0.050', 'Erythrocytes': '-0.158', 'Hematopoietic stem cells': '-0.211', 'B-cells (Spleen)': '0.266', 'NK-cells (Spleen)': '0.309', 'Amygdala excitatory': '1.0', 'Cerebellar inhibitory': '0.9', 'Cge interneuron': '0.7', 'Deep-layer corticothalamic and 6b': '1.5', 'Deep-layer intratelencephalic': '0.7', 'Deep-layer near-projecting': '0.7', 'Eccentric medium spiny neuron': '0.6', 'Hippocampal ca1-3': '1.9', 'Hippocampal ca4': '1.2', 'Hippocampal dentate gyrus': '1.1', 'Lamp5-lhx6 and chandelier': '0.5', 'Lower rhombic lip': '0.8', 'Mammillary body': '0.6', 'Medium spiny neuron': '0.7', 'Mge interneuron': '1.7', 'Midbrain-derived inhibitory': '0.7', 'Miscellaneous': '0.9', 'Splatter': '3.8', 'Thalamic excitatory': '0.5', 'Upper rhombic lip': '0.8', 'Upper-layer intratelencephalic': '0.6', 'Astrocyte': '4.4', 'Bergmann glia': '0.2', 'Central nervous system macrophage': '0.6', 'Choroid plexus epithelial cell': '52.1', 'Committed oligodendrocyte precursor': '41.5', 'Ependymal cell': '4.8', 'Oligodendrocyte': '53.1', 'Oligodendrocyte precursor cell': '2.4', 'Endothelial cell': '0.7', 'Pericyte': '0.3', 'Vascular associated smooth muscle cell': '0.0', 'Fibroblast': '17.4', 'Leukocyte': '1.1', 'Basophil': '0.0', 'Eosinophil': '0.0', 'Neutrophil': '0.0', 'Classical monocyte': '0.0', 'Non-classical monocyte': '0.0', 'Intermediate monocyte': '0.0', 'T-reg': '2.3', 'GdT-cell': '0.0', 'MAIT T-cell': '0.0', 'Memory CD4 T-cell': '0.0', 'Naive CD4 T-cell': '0.1', 'Memory CD8 T-cell': '0.2', 'Naive CD8 T-cell': '0.3', 'Memory B-cell': '0.0', 'Naive B-cell': '0.1', 'Plasmacytoid DC': '46.6', 'Myeloid DC': '8.5', 'NK-cell': '0.1', 'Total PBMC': '0.7', 'Vd2 gdTCR': '0.0', 'Memory CD4 T-cell Th1\\/Th17': '0.1', 'Memory CD4 T-cell Th17': '0.2', 'Memory CD4 T-cell Th2': '2.9', 'Non-Vd2 gdTCR': '0.1', 'Memory CD4 T-cell Th1': '0.3', 'Memory CD4 T-cell TFH': '0.5', 'Terminal effector memory CD4 T-cell': '0.0', 'Central memory CD8 T-cell': '4.8', 'Effector memory CD8 T-cell': '0.0', 'Terminal effector memory CD8 T-cell': '0.6', 'Non-switched memory B-cell': '0.0', 'Plasmablast': '3.3', 'Switched memory B-cell': '0.0', 'Exhausted memory B-cell': '0.7', 'Progenitor cell': '2.3', 'Memory T-reg': '1.3', 'Naive CD4 T-cell activated': '0.3', 'Naive CD8 T-cell activated': '0.6', 'Naive T-reg': '0.1'} | 1O6S, 2O72, 2OMT, 2OMU, 2OMV, 2OMX, 2OMY, 2OMZ, 3FF7, 3FF8, 3L6X, 3L6Y, 4ZT1, 4ZTE, 6CXY, 6OLE, 6OLF, 6OLG, 6VEL, 7STZ, 8H62 | {'Adipose Tissue': 1.2125261088039867, 'Adrenal Gland': 0.1914223992248062, 'Bladder': 39.2033519047619, 'Blood': 1.340954264800861, 'Blood Vessel': 0.3121561692883895, 'Brain': 0.8550442199091597, 'Breast': 38.54918344226579, 'Cervix Uteri': 23.539115789473684, 'Colon': 43.41292142490372, 'Esophagus': 53.97513367404844, 'Fallopian Tube': 14.900277777777776, 'Heart': 0.119140469221835, 'Kidney': 25.040449438202245, 'Liver': 26.60802654867257, 'Lung': 35.447986366782004, 'Muscle': 0.1378936151930261, 'Nerve': 17.518468982229404, 'Ovary': 3.6515122222222223, 'Pancreas': 56.89676829268293, 'Pituitary': 24.68741660777385, 'Prostate': 61.279967346938776, 'Salivary Gland': 92.01685185185184, 'Skin': 79.77571720232172, 'Small Intestine': 71.7519320855615, 'Spleen': 10.061029045643156, 'Stomach': 58.07813805013927, 'Testis': 0.8144204986149585, 'Thyroid': 135.176797856049, 'Uterus': 1.442593943661972, 'Vagina': 86.52345512820513} | CKAP2 | MSTPAVPQDLQLPPSQRAQSAFKEQRRQKLKEHLLRRKTLFAYKQENEMLSSRDQRVVTSEDQVQEGTKVLKLKTKMADKENMKRPAESKNNTVVGKHCIPLKPSNELTNSTVVIDTHKPKDSNQTPHLLLTEDDPQSQHMTLSQAFHLKNNSKKKQMTTEKQKQDANMPKKPVLGSYRGQIVQSKINSFRKPLQVKDESSAATKKLSATIPKATKPQPVNTSSVTVKSNRSSNMTATTKFVSTTSQNTQLVRPPIRSHHSNTRDTVKQGISRTSANVTIRKGPHEKELLQSKTALSSVKTSSSQGIIRNKTLSRSIASEVIARPASLSNDKLMEKSEPVDQRRHTAGKAIVDSRSAQPKETSEERKARLSEWKAGKGRVLKRPPNSVVTQHEPAGQNEKPVGSFWTTMAEEDEQRLFTEKVNNTFSECLNLINEGCPKEDILVTLNDLIKNIPDAKKLVKYWICLALIEPITSPIENIIAIYEKAILAGAQVR | Homo sapiens | null | Not found | {} | null | {'Adipose Tissue': 4.280651976744187, 'Adrenal Gland': 7.484100387596899, 'Bladder': 5.046142857142857, 'Blood': 10.339545209903122, 'Blood Vessel': 3.654278951310862, 'Brain': 5.928422823618471, 'Breast': 3.9675289760348584, 'Cervix Uteri': 4.338315789473684, 'Colon': 4.377415789473684, 'Esophagus': 6.548149134948098, 'Fallopian Tube': 3.0292222222222223, 'Heart': 1.8164202787456445, 'Kidney': 2.3842370786516853, 'Liver': 1.4220862831858407, 'Lung': 5.353738062283737, 'Muscle': 2.016712391033624, 'Nerve': 4.852846526655896, 'Ovary': 3.9144055555555552, 'Pancreas': 0.919306493902439, 'Pituitary': 7.795000000000001, 'Prostate': 4.071029795918367, 'Salivary Gland': 5.9194506172839505, 'Skin': 20.163732448866774, 'Small Intestine': 6.9891016042780745, 'Spleen': 8.95429460580913, 'Stomach': 2.773699164345404, 'Testis': 27.759362880886425, 'Thyroid': 4.374940275650842, 'Uterus': 3.97512676056338, 'Vagina': 8.247121794871795} | [39.93, 46.46, 52.9, 44.21, 41.4, 39.93, 35.91, 38.61, 36.44, 36.25, 34.86, 32.82, 32.01, 32.75, 31.69, 35.64, 36.35, 34.66, 33.32, 32.71, 35.01, 30.17, 37.05, 36.53, 48.19, 58.22, 64.94, 73.22, 78.33, 82.63, 85.79, 89.39, 87.89, 85.58, 83.93, 89.1, 89.27, 90.66, 87.86, 86.2, 82.97, 72.75, 73.3, 76.44, 82.38, 82.41, 79.49, 86.6, 76.32, 85.48, 88.69, 84.35, 87.75, 90.57, 88.72, 89.46, 87.48, 85.3, 81.72, 79.46, 77.26, 69.01, 67.1, 62.83, 67.71, 74.96, 82.95, 86.74, 86.35, 86.49, 84.6, 85.99, 85.64, 87.19, 89.23, 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Forms a ternary complex composed of ADAM10, CADH1 and EPHA4, | null | null | KLRG1, SPEF1, DLGAP5, AJAP1, RAPGEF2, RAB8B, PIP5K1C, PKP2, TRPV4, CTNNB1, CAV1, DDR1, TBC1D2, CTNNA1, JUP, CTNND1, PSEN1, LIMA1, CDH1, JUP, ADAM10, CADH1 , EPHA4, | null | null | null | null | Homodimer | null | 79.91949 | 0.474025 | null | null | 1,063 |
P12830 | Q8WWK9-5 | null | degron_data | CDH1 | MGPWSRSLSALLLLLQVSSWLCQEPEPCHPGFDAESYTFTVPRRHLERGRVLGRVNFEDCTGRQRTAYFSLDTRFKVGTDGVITVKRPLRFHNPQIHFLVYAWDSTYRKFSTKVTLNTVGHHHRPPPHQASVSGIQAELLTFPNSSPGLRRQKRDWVIPPISCPENEKGPFPKNLVQIKSNKDKEGKVFYSITGQGADTPPVGVFIIERETGWLKVTEPLDRERIATYTLFSHAVSSNGNAVEDPMEILITVTDQNDNKPEFTQEVFKGSVMEGALPGTSVMEVTATDADDDVNTYNAAIAYTILSQDPELPDKNMFTINRNTGVISVVTTGLDRESFPTYTLVVQAADLQGEGLSTTATAVITVTDTNDNPPIFNPTTYKGQVPENEANVVITTLKVTDADAPNTPAWEAVYTILNDDGGQFVVTTNPVNNDGILKTAKGLDFEAKQQYILHVAVTNVVPFEVSLTTSTATVTVDVLDVNEAPIFVPPEKRVEVSEDFGVGQEITSYTAQEPDTFMEQKITYRIWRDTANWLEINPDTGAISTRAELDREDFEHVKNSTYTALIIATDNGSPVATGTGTLLLILSDVNDNAPIPEPRTIFFCERNPKPQVINIIDADLPPNTSPFTAELTHGASANWTIQYNDPTQESIILKPKMALEVGDYKINLKLMDNQNKDQVTTLEVSVCDCEGAAGVCRKAQPVEAGLQIPAILGILGGILALLILILLLLLFLRRRAVVKEPLLPPEDDTRDNVYYYDEEGGGEEDQDFDLSQLHRGLDARPEVTRNDVAPTLMSVPRYLPRPANPDEIGNFIDENLKAADTDPTAPPYDSLLVFDYEGSGSEAASLSSLNSSESDKDQDYDYLNEWGNRFKKLADMYGGGEDD | Homo sapiens | Cell junction, adherens junction, Cell membrane, Endosome, Golgi apparatus, trans-Golgi network, Cytoplasm, Cell junction, desmosome | Tissue enhanced (parathyroid) | {'Ciliated cells': '119.1', 'Basal respiratory cells': '71.1', 'Club cells': '97.3', 'Ionocytes': '81.0', 'Mucus glandular cells': '155.0', 'Serous glandular cells': '67.8', 'Gastric mucus-secreting cells': '133.2', 'Proximal enterocytes': '140.9', 'Paneth cells': '125.1', 'Distal enterocytes': '307.5', 'Intestinal goblet cells': '173.5', 'Exocrine glandular cells': '-0.605', 'Basal prostatic cells': '68.3', 'Prostatic glandular cells': '186.7', 'Breast glandular cells': '0.773', 'Breast myoepithelial cells': '0.700', 'Glandular and luminal cells': '313.0', 'Secretory cells': '82.3', 'Basal keratinocytes': '102.5', 'Suprabasal keratinocytes': '162.6', 'Basal squamous epithelial cells': '51.0', 'Squamous epithelial cells': '106.9', 'Alveolar cells type 1': '0.437', 'Alveolar cells type 2': '0.706', 'Salivary duct cells': '95.9', 'Ductal cells': '0.541', 'Hepatocytes': '0.600', 'Cholangiocytes': '129.7', 'Proximal tubular cells': '0.042', 'Distal tubular cells': '0.0', 'Collecting duct cells': '143.9', 'Mesothelial cells': '0.799', 'Sertoli cells': '0.252', 'Granulosa cells': '12.9', 'Enteroendocrine cells': '92.4', 'Pancreatic endocrine cells': '78.1', 'Leydig cells': '0.264', 'Excitatory neurons': '0.7', 'Inhibitory neurons': '1.3', 'Cone photoreceptor cells': '0.0', 'Rod photoreceptor cells': '0.0', 'Bipolar cells': '0.2', 'Horizontal cells': '0.6', 'Astrocytes': '0.6', 'Oligodendrocyte precursor cells': '0.5', 'Oligodendrocytes': '29.9', 'Microglial cells': '0.9', 'Muller glia cells': '0.1', 'Schwann cells': '0.131', 'Spermatogonia': '0.392', 'Spermatocytes': '0.193', 'Early spermatids': '-0.217', 'Late spermatids': '-0.290', 'Oocytes': '16.9', 'Cytotrophoblasts': '119.2', 'Syncytiotrophoblasts': '45.0', 'Extravillous trophoblasts': '24.9', 'Endothelial cells': '6.1', 'Lymphatic endothelial cells': '0.4', 'Cardiomyocytes': '0.135', 'Skeletal myocytes': '0.107', 'Smooth muscle cells': '5.8', 'Adipocytes': '2.1', 'Melanocytes': '0.335', 'Fibroblasts': '6.5', 'Peritubular cells': '0.210', 'Endometrial stromal cells': '27.7', 'Ovarian stromal cells': '0.7', 'Undifferentiated cells': '101.6', 'T-cells': '2.9', 'B-cells': '4.4', 'Plasma cells': '6.1', 'Nk-cells': '0.0', 'Granulocytes': '8.4', 'Monocytes': '0.0', 'Macrophages': '6.0', 'Hofbauer cells': '4.3', 'Kupffer cells': '1.0', 'Dendritic cells': '5.9', 'Langerhans cells': '0.304', 'Erythroid cells': '0.036', 'Adipocytes (Subcutaneous)': '-0.081', 'Adipocytes (Visceral)': '-0.209', 'Breast glandular cells (progenitors)': '0.538', 'Adipocytes (Breast)': '-0.689', 'Colon enterocytes': '0.790', 'Colon enteroendocrine cells': '0.112', 'Enteric glia cells': '-0.048', 'Mitotic cells (Colon)': '0.299', 'Mitotic cells (Heart)': '0.120', 'Podocytes': '-0.118', 'Ascending Loop of Henle cells': '0.475', 'Intercalated cells': '0.212', 'Cholangiocyte': '0.090', 'NK-cells (Liver)': '-0.005', 'Respiratory ciliated cells': '-0.012', 'Mitotic cells (Lung)': '0.071', 'NK-cells (Lung)': '-0.266', 'B-cells (Lung)': '-0.296', 'Alpha cells': '0.270', 'Beta cells': '0.152', 'Prostate glandular cells': '0.764', 'Prostate basal glandular cells': '0.540', 'Urothelial cells': '0.205', 'Keratinocyte (other)': '0.510', 'Keratinocyte (granular)': '0.055', 'Hair cortex cells': '0.080', 'Inner root sheath cells': '0.131', 'Outer root sheath cells': '0.175', 'Sebaceous gland cells': '0.156', 'Eccrine sweat gland cells': '-0.207', 'Adipocytes (Skin)': '-0.244', 'Mitotic cells (Skin)': '0.442', 'Parietal cells': '0.654', 'Chief cells': '0.649', 'Gastric mucous cells': '0.781', 'Gastric enteroendocrine cells': '0.590', 'Mitotic cells (Stomach)': '0.445', 'Parafollicular cells': '0.173', 'Thyroid glandular cells': '0.865', 'Mitotic cells (Thyroid)': '-0.081', 'Adrenal cortex cells': '0.051', 'Adrenal medulla cells': '0.087', 'Mitotic cells (Adrenal gland)': '0.072', 'Minor salivary glandular cells': '0.371', 'Minor salivary gland ductal cells': '-0.142', 'Minor salivary gland basal cells': '0.582', 'Mitotic cells (Minor salivary gland)': '0.567', 'Adipocytes (Minor salivary gland)': '0.050', 'Somatotropes': '0.121', 'Lactotropes': '0.322', 'Gonadotropes': '0.330', 'Corticotropes': '0.180', 'Thyrotropes': '0.496', 'Undifferentiated cells (Pituitary gland)': '-0.108', 'Mitotic cells (Spleen)': '-0.228', 'Platelets': '-0.050', 'Erythrocytes': '-0.158', 'Hematopoietic stem cells': '-0.211', 'B-cells (Spleen)': '0.266', 'NK-cells (Spleen)': '0.309', 'Amygdala excitatory': '1.0', 'Cerebellar inhibitory': '0.9', 'Cge interneuron': '0.7', 'Deep-layer corticothalamic and 6b': '1.5', 'Deep-layer intratelencephalic': '0.7', 'Deep-layer near-projecting': '0.7', 'Eccentric medium spiny neuron': '0.6', 'Hippocampal ca1-3': '1.9', 'Hippocampal ca4': '1.2', 'Hippocampal dentate gyrus': '1.1', 'Lamp5-lhx6 and chandelier': '0.5', 'Lower rhombic lip': '0.8', 'Mammillary body': '0.6', 'Medium spiny neuron': '0.7', 'Mge interneuron': '1.7', 'Midbrain-derived inhibitory': '0.7', 'Miscellaneous': '0.9', 'Splatter': '3.8', 'Thalamic excitatory': '0.5', 'Upper rhombic lip': '0.8', 'Upper-layer intratelencephalic': '0.6', 'Astrocyte': '4.4', 'Bergmann glia': '0.2', 'Central nervous system macrophage': '0.6', 'Choroid plexus epithelial cell': '52.1', 'Committed oligodendrocyte precursor': '41.5', 'Ependymal cell': '4.8', 'Oligodendrocyte': '53.1', 'Oligodendrocyte precursor cell': '2.4', 'Endothelial cell': '0.7', 'Pericyte': '0.3', 'Vascular associated smooth muscle cell': '0.0', 'Fibroblast': '17.4', 'Leukocyte': '1.1', 'Basophil': '0.0', 'Eosinophil': '0.0', 'Neutrophil': '0.0', 'Classical monocyte': '0.0', 'Non-classical monocyte': '0.0', 'Intermediate monocyte': '0.0', 'T-reg': '2.3', 'GdT-cell': '0.0', 'MAIT T-cell': '0.0', 'Memory CD4 T-cell': '0.0', 'Naive CD4 T-cell': '0.1', 'Memory CD8 T-cell': '0.2', 'Naive CD8 T-cell': '0.3', 'Memory B-cell': '0.0', 'Naive B-cell': '0.1', 'Plasmacytoid DC': '46.6', 'Myeloid DC': '8.5', 'NK-cell': '0.1', 'Total PBMC': '0.7', 'Vd2 gdTCR': '0.0', 'Memory CD4 T-cell Th1\\/Th17': '0.1', 'Memory CD4 T-cell Th17': '0.2', 'Memory CD4 T-cell Th2': '2.9', 'Non-Vd2 gdTCR': '0.1', 'Memory CD4 T-cell Th1': '0.3', 'Memory CD4 T-cell TFH': '0.5', 'Terminal effector memory CD4 T-cell': '0.0', 'Central memory CD8 T-cell': '4.8', 'Effector memory CD8 T-cell': '0.0', 'Terminal effector memory CD8 T-cell': '0.6', 'Non-switched memory B-cell': '0.0', 'Plasmablast': '3.3', 'Switched memory B-cell': '0.0', 'Exhausted memory B-cell': '0.7', 'Progenitor cell': '2.3', 'Memory T-reg': '1.3', 'Naive CD4 T-cell activated': '0.3', 'Naive CD8 T-cell activated': '0.6', 'Naive T-reg': '0.1'} | 1O6S, 2O72, 2OMT, 2OMU, 2OMV, 2OMX, 2OMY, 2OMZ, 3FF7, 3FF8, 3L6X, 3L6Y, 4ZT1, 4ZTE, 6CXY, 6OLE, 6OLF, 6OLG, 6VEL, 7STZ, 8H62 | {'Adipose Tissue': 1.2125261088039867, 'Adrenal Gland': 0.1914223992248062, 'Bladder': 39.2033519047619, 'Blood': 1.340954264800861, 'Blood Vessel': 0.3121561692883895, 'Brain': 0.8550442199091597, 'Breast': 38.54918344226579, 'Cervix Uteri': 23.539115789473684, 'Colon': 43.41292142490372, 'Esophagus': 53.97513367404844, 'Fallopian Tube': 14.900277777777776, 'Heart': 0.119140469221835, 'Kidney': 25.040449438202245, 'Liver': 26.60802654867257, 'Lung': 35.447986366782004, 'Muscle': 0.1378936151930261, 'Nerve': 17.518468982229404, 'Ovary': 3.6515122222222223, 'Pancreas': 56.89676829268293, 'Pituitary': 24.68741660777385, 'Prostate': 61.279967346938776, 'Salivary Gland': 92.01685185185184, 'Skin': 79.77571720232172, 'Small Intestine': 71.7519320855615, 'Spleen': 10.061029045643156, 'Stomach': 58.07813805013927, 'Testis': 0.8144204986149585, 'Thyroid': 135.176797856049, 'Uterus': 1.442593943661972, 'Vagina': 86.52345512820513} | CKAP2 | MSTPAVPQDLQLPPSQRAQSAFKEQRRQKLKEHLLRRKTLFAYKQENEMLSSRDQRVVTSEDQVQEGTKVLKLKTKMADKENMKRPAESKNNTVVGKHCIPLKPSNELTNSTVVIDTHKPKDSNQTPHLLLTEDDPQSQHMTLSQAFHLKNNSKKKQMTTEKQKQDANMPKKPVLGSYRGQIVQSKINSFRKPLQVKDESSAATKKLSATIPKATKPQPVNTSSVTVKSNRSSNMTATTKFVSTTSQNTQLVRPPIRSHHSNTRDTVKQGISRTSANVTIRKGPHEKELLQSKTALSSVKTSSSQGIIRNKTLSRSIASEVIARPASLSNDKLMEKSEPVDQRRHTAGKAIVDSRSAQPKETSEERKARLSEWKAGKGRVLKRPPNSVVTQHEPAGQNEKPVGSFWTTMAEEDEQRLFTEKVNNTFSECLNLINEGCPKEDILVTLNDLIKNIPDAKKLVKYWICLALIEPITSPIENIIAIYEKAILAGAQPIEEMRHTIVDILTMKSQEKANLGENMEKSCASKEEVKEVSIEDTGVDVDPEKLEMESKLHRNLLFQDCEKEQDNKTKDPTHDVKTPNTETRTSCLIKYNVSTTPYLQSVKKKVQFDGTNSAFKELKFLTPVRRSRRLQEKTSKLPDMLKDHYPCVSSLEQLTELGRETDAFVCRPNAALCRVYYEADTT | Homo sapiens | null | Not found | {} | null | {'Adipose Tissue': 4.280651976744187, 'Adrenal Gland': 7.484100387596899, 'Bladder': 5.046142857142857, 'Blood': 10.339545209903122, 'Blood Vessel': 3.654278951310862, 'Brain': 5.928422823618471, 'Breast': 3.9675289760348584, 'Cervix Uteri': 4.338315789473684, 'Colon': 4.377415789473684, 'Esophagus': 6.548149134948098, 'Fallopian Tube': 3.0292222222222223, 'Heart': 1.8164202787456445, 'Kidney': 2.3842370786516853, 'Liver': 1.4220862831858407, 'Lung': 5.353738062283737, 'Muscle': 2.016712391033624, 'Nerve': 4.852846526655896, 'Ovary': 3.9144055555555552, 'Pancreas': 0.919306493902439, 'Pituitary': 7.795000000000001, 'Prostate': 4.071029795918367, 'Salivary Gland': 5.9194506172839505, 'Skin': 20.163732448866774, 'Small Intestine': 6.9891016042780745, 'Spleen': 8.95429460580913, 'Stomach': 2.773699164345404, 'Testis': 27.759362880886425, 'Thyroid': 4.374940275650842, 'Uterus': 3.97512676056338, 'Vagina': 8.247121794871795} | [39.93, 46.46, 52.9, 44.21, 41.4, 39.93, 35.91, 38.61, 36.44, 36.25, 34.86, 32.82, 32.01, 32.75, 31.69, 35.64, 36.35, 34.66, 33.32, 32.71, 35.01, 30.17, 37.05, 36.53, 48.19, 58.22, 64.94, 73.22, 78.33, 82.63, 85.79, 89.39, 87.89, 85.58, 83.93, 89.1, 89.27, 90.66, 87.86, 86.2, 82.97, 72.75, 73.3, 76.44, 82.38, 82.41, 79.49, 86.6, 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composed of at least E-cadherin/CDH1, beta-catenin/CTNNB1 or gamma-catenin/JUP, and potentially alpha-catenin/CTNNA1. Forms a ternary complex composed of ADAM10, CADH1 and EPHA4, | null | null | KLRG1, SPEF1, DLGAP5, AJAP1, RAPGEF2, RAB8B, PIP5K1C, PKP2, TRPV4, CTNNB1, CAV1, DDR1, TBC1D2, CTNNA1, JUP, CTNND1, PSEN1, LIMA1, CDH1, JUP, ADAM10, CADH1 , EPHA4, | null | null | null | null | Homodimer | null | 79.91949 | 0.474025 | null | null | 1,063 |
P12830 | Q8WWL7 | null | degron_data | CDH1 | MGPWSRSLSALLLLLQVSSWLCQEPEPCHPGFDAESYTFTVPRRHLERGRVLGRVNFEDCTGRQRTAYFSLDTRFKVGTDGVITVKRPLRFHNPQIHFLVYAWDSTYRKFSTKVTLNTVGHHHRPPPHQASVSGIQAELLTFPNSSPGLRRQKRDWVIPPISCPENEKGPFPKNLVQIKSNKDKEGKVFYSITGQGADTPPVGVFIIERETGWLKVTEPLDRERIATYTLFSHAVSSNGNAVEDPMEILITVTDQNDNKPEFTQEVFKGSVMEGALPGTSVMEVTATDADDDVNTYNAAIAYTILSQDPELPDKNMFTINRNTGVISVVTTGLDRESFPTYTLVVQAADLQGEGLSTTATAVITVTDTNDNPPIFNPTTYKGQVPENEANVVITTLKVTDADAPNTPAWEAVYTILNDDGGQFVVTTNPVNNDGILKTAKGLDFEAKQQYILHVAVTNVVPFEVSLTTSTATVTVDVLDVNEAPIFVPPEKRVEVSEDFGVGQEITSYTAQEPDTFMEQKITYRIWRDTANWLEINPDTGAISTRAELDREDFEHVKNSTYTALIIATDNGSPVATGTGTLLLILSDVNDNAPIPEPRTIFFCERNPKPQVINIIDADLPPNTSPFTAELTHGASANWTIQYNDPTQESIILKPKMALEVGDYKINLKLMDNQNKDQVTTLEVSVCDCEGAAGVCRKAQPVEAGLQIPAILGILGGILALLILILLLLLFLRRRAVVKEPLLPPEDDTRDNVYYYDEEGGGEEDQDFDLSQLHRGLDARPEVTRNDVAPTLMSVPRYLPRPANPDEIGNFIDENLKAADTDPTAPPYDSLLVFDYEGSGSEAASLSSLNSSESDKDQDYDYLNEWGNRFKKLADMYGGGEDD | Homo sapiens | Cell junction, adherens junction, Cell membrane, Endosome, Golgi apparatus, trans-Golgi network, Cytoplasm, Cell junction, desmosome | Tissue enhanced (parathyroid) | {'Ciliated cells': '119.1', 'Basal respiratory cells': '71.1', 'Club cells': '97.3', 'Ionocytes': '81.0', 'Mucus glandular cells': '155.0', 'Serous glandular cells': '67.8', 'Gastric mucus-secreting cells': '133.2', 'Proximal enterocytes': '140.9', 'Paneth cells': '125.1', 'Distal enterocytes': '307.5', 'Intestinal goblet cells': '173.5', 'Exocrine glandular cells': '-0.605', 'Basal prostatic cells': '68.3', 'Prostatic glandular cells': '186.7', 'Breast glandular cells': '0.773', 'Breast myoepithelial cells': '0.700', 'Glandular and luminal cells': '313.0', 'Secretory cells': '82.3', 'Basal keratinocytes': '102.5', 'Suprabasal keratinocytes': '162.6', 'Basal squamous epithelial cells': '51.0', 'Squamous epithelial cells': '106.9', 'Alveolar cells type 1': '0.437', 'Alveolar cells type 2': '0.706', 'Salivary duct cells': '95.9', 'Ductal cells': '0.541', 'Hepatocytes': '0.600', 'Cholangiocytes': '129.7', 'Proximal tubular cells': '0.042', 'Distal tubular cells': '0.0', 'Collecting duct cells': '143.9', 'Mesothelial cells': '0.799', 'Sertoli cells': '0.252', 'Granulosa cells': '12.9', 'Enteroendocrine cells': '92.4', 'Pancreatic endocrine cells': '78.1', 'Leydig cells': '0.264', 'Excitatory neurons': '0.7', 'Inhibitory neurons': '1.3', 'Cone photoreceptor cells': '0.0', 'Rod photoreceptor cells': '0.0', 'Bipolar cells': '0.2', 'Horizontal cells': '0.6', 'Astrocytes': '0.6', 'Oligodendrocyte precursor cells': '0.5', 'Oligodendrocytes': '29.9', 'Microglial cells': '0.9', 'Muller glia cells': '0.1', 'Schwann cells': '0.131', 'Spermatogonia': '0.392', 'Spermatocytes': '0.193', 'Early spermatids': '-0.217', 'Late spermatids': '-0.290', 'Oocytes': '16.9', 'Cytotrophoblasts': '119.2', 'Syncytiotrophoblasts': '45.0', 'Extravillous trophoblasts': '24.9', 'Endothelial cells': '6.1', 'Lymphatic endothelial cells': '0.4', 'Cardiomyocytes': '0.135', 'Skeletal myocytes': '0.107', 'Smooth muscle cells': '5.8', 'Adipocytes': '2.1', 'Melanocytes': '0.335', 'Fibroblasts': '6.5', 'Peritubular cells': '0.210', 'Endometrial stromal cells': '27.7', 'Ovarian stromal cells': '0.7', 'Undifferentiated cells': '101.6', 'T-cells': '2.9', 'B-cells': '4.4', 'Plasma cells': '6.1', 'Nk-cells': '0.0', 'Granulocytes': '8.4', 'Monocytes': '0.0', 'Macrophages': '6.0', 'Hofbauer cells': '4.3', 'Kupffer cells': '1.0', 'Dendritic cells': '5.9', 'Langerhans cells': '0.304', 'Erythroid cells': '0.036', 'Adipocytes (Subcutaneous)': '-0.081', 'Adipocytes (Visceral)': '-0.209', 'Breast glandular cells (progenitors)': '0.538', 'Adipocytes (Breast)': '-0.689', 'Colon enterocytes': '0.790', 'Colon enteroendocrine cells': '0.112', 'Enteric glia cells': '-0.048', 'Mitotic cells (Colon)': '0.299', 'Mitotic cells (Heart)': '0.120', 'Podocytes': '-0.118', 'Ascending Loop of Henle cells': '0.475', 'Intercalated cells': '0.212', 'Cholangiocyte': '0.090', 'NK-cells (Liver)': '-0.005', 'Respiratory ciliated cells': '-0.012', 'Mitotic cells (Lung)': '0.071', 'NK-cells (Lung)': '-0.266', 'B-cells (Lung)': '-0.296', 'Alpha cells': '0.270', 'Beta cells': '0.152', 'Prostate glandular cells': '0.764', 'Prostate basal glandular cells': '0.540', 'Urothelial cells': '0.205', 'Keratinocyte (other)': '0.510', 'Keratinocyte (granular)': '0.055', 'Hair cortex cells': '0.080', 'Inner root sheath cells': '0.131', 'Outer root sheath cells': '0.175', 'Sebaceous gland cells': '0.156', 'Eccrine sweat gland cells': '-0.207', 'Adipocytes (Skin)': '-0.244', 'Mitotic cells (Skin)': '0.442', 'Parietal cells': '0.654', 'Chief cells': '0.649', 'Gastric mucous cells': '0.781', 'Gastric enteroendocrine cells': '0.590', 'Mitotic cells (Stomach)': '0.445', 'Parafollicular cells': '0.173', 'Thyroid glandular cells': '0.865', 'Mitotic cells (Thyroid)': '-0.081', 'Adrenal cortex cells': '0.051', 'Adrenal medulla cells': '0.087', 'Mitotic cells (Adrenal gland)': '0.072', 'Minor salivary glandular cells': '0.371', 'Minor salivary gland ductal cells': '-0.142', 'Minor salivary gland basal cells': '0.582', 'Mitotic cells (Minor salivary gland)': '0.567', 'Adipocytes (Minor salivary gland)': '0.050', 'Somatotropes': '0.121', 'Lactotropes': '0.322', 'Gonadotropes': '0.330', 'Corticotropes': '0.180', 'Thyrotropes': '0.496', 'Undifferentiated cells (Pituitary gland)': '-0.108', 'Mitotic cells (Spleen)': '-0.228', 'Platelets': '-0.050', 'Erythrocytes': '-0.158', 'Hematopoietic stem cells': '-0.211', 'B-cells (Spleen)': '0.266', 'NK-cells (Spleen)': '0.309', 'Amygdala excitatory': '1.0', 'Cerebellar inhibitory': '0.9', 'Cge interneuron': '0.7', 'Deep-layer corticothalamic and 6b': '1.5', 'Deep-layer intratelencephalic': '0.7', 'Deep-layer near-projecting': '0.7', 'Eccentric medium spiny neuron': '0.6', 'Hippocampal ca1-3': '1.9', 'Hippocampal ca4': '1.2', 'Hippocampal dentate gyrus': '1.1', 'Lamp5-lhx6 and chandelier': '0.5', 'Lower rhombic lip': '0.8', 'Mammillary body': '0.6', 'Medium spiny neuron': '0.7', 'Mge interneuron': '1.7', 'Midbrain-derived inhibitory': '0.7', 'Miscellaneous': '0.9', 'Splatter': '3.8', 'Thalamic excitatory': '0.5', 'Upper rhombic lip': '0.8', 'Upper-layer intratelencephalic': '0.6', 'Astrocyte': '4.4', 'Bergmann glia': '0.2', 'Central nervous system macrophage': '0.6', 'Choroid plexus epithelial cell': '52.1', 'Committed oligodendrocyte precursor': '41.5', 'Ependymal cell': '4.8', 'Oligodendrocyte': '53.1', 'Oligodendrocyte precursor cell': '2.4', 'Endothelial cell': '0.7', 'Pericyte': '0.3', 'Vascular associated smooth muscle cell': '0.0', 'Fibroblast': '17.4', 'Leukocyte': '1.1', 'Basophil': '0.0', 'Eosinophil': '0.0', 'Neutrophil': '0.0', 'Classical monocyte': '0.0', 'Non-classical monocyte': '0.0', 'Intermediate monocyte': '0.0', 'T-reg': '2.3', 'GdT-cell': '0.0', 'MAIT T-cell': '0.0', 'Memory CD4 T-cell': '0.0', 'Naive CD4 T-cell': '0.1', 'Memory CD8 T-cell': '0.2', 'Naive CD8 T-cell': '0.3', 'Memory B-cell': '0.0', 'Naive B-cell': '0.1', 'Plasmacytoid DC': '46.6', 'Myeloid DC': '8.5', 'NK-cell': '0.1', 'Total PBMC': '0.7', 'Vd2 gdTCR': '0.0', 'Memory CD4 T-cell Th1\\/Th17': '0.1', 'Memory CD4 T-cell Th17': '0.2', 'Memory CD4 T-cell Th2': '2.9', 'Non-Vd2 gdTCR': '0.1', 'Memory CD4 T-cell Th1': '0.3', 'Memory CD4 T-cell TFH': '0.5', 'Terminal effector memory CD4 T-cell': '0.0', 'Central memory CD8 T-cell': '4.8', 'Effector memory CD8 T-cell': '0.0', 'Terminal effector memory CD8 T-cell': '0.6', 'Non-switched memory B-cell': '0.0', 'Plasmablast': '3.3', 'Switched memory B-cell': '0.0', 'Exhausted memory B-cell': '0.7', 'Progenitor cell': '2.3', 'Memory T-reg': '1.3', 'Naive CD4 T-cell activated': '0.3', 'Naive CD8 T-cell activated': '0.6', 'Naive T-reg': '0.1'} | 1O6S, 2O72, 2OMT, 2OMU, 2OMV, 2OMX, 2OMY, 2OMZ, 3FF7, 3FF8, 3L6X, 3L6Y, 4ZT1, 4ZTE, 6CXY, 6OLE, 6OLF, 6OLG, 6VEL, 7STZ, 8H62 | {'Adipose Tissue': 1.2125261088039867, 'Adrenal Gland': 0.1914223992248062, 'Bladder': 39.2033519047619, 'Blood': 1.340954264800861, 'Blood Vessel': 0.3121561692883895, 'Brain': 0.8550442199091597, 'Breast': 38.54918344226579, 'Cervix Uteri': 23.539115789473684, 'Colon': 43.41292142490372, 'Esophagus': 53.97513367404844, 'Fallopian Tube': 14.900277777777776, 'Heart': 0.119140469221835, 'Kidney': 25.040449438202245, 'Liver': 26.60802654867257, 'Lung': 35.447986366782004, 'Muscle': 0.1378936151930261, 'Nerve': 17.518468982229404, 'Ovary': 3.6515122222222223, 'Pancreas': 56.89676829268293, 'Pituitary': 24.68741660777385, 'Prostate': 61.279967346938776, 'Salivary Gland': 92.01685185185184, 'Skin': 79.77571720232172, 'Small Intestine': 71.7519320855615, 'Spleen': 10.061029045643156, 'Stomach': 58.07813805013927, 'Testis': 0.8144204986149585, 'Thyroid': 135.176797856049, 'Uterus': 1.442593943661972, 'Vagina': 86.52345512820513} | CCNB3 | MLLPLPPQSSKPVPKKSQSSKIVPSHHDPSEKTGENCQTKISPSSLQESPSSLQGALKKRSAFEDLTNASQCQPVQPKKEANKEFVKVVSKKINRNTHALGLAKKNKRNLKWHKLEVTPVVASTTVVPNIMEKPLILDISTTSKTPNTEEASLFRKPLVLKEEPTIEDETLINKSLSLKKCSNHEEVSLLEKLQPLQEESDSDDAFVIEPMTFKKTHKTEEAAITKKTLSLKKKMCASQRKQSCQEESLAVQDVNMEEDSFFMESMSFKKKPKTEESIPTHKLSSLKKKCTIYGKICHFRKPPVLQTTICGAMSSIKKPTTEKETLFQELSVLQEKHTTEHEMSILKKSLALQKTNFKEDSLVKESLAFKKKPSTEEAIMMPVILKEQCMTEGKRSRLKPLVLQEITSGEKSLIMKPLSIKEKPSTEKESFSQEPSALQKKHTTQEEVSILKEPSSLLKSPTEESPFDEALAFTKKCTIEEAPPTKKPLILKRKHATQGTMSHLKKPLILQTTSGEKSLIKEPLPFKEEKVSLKKKCTTQEMMSICPELLDFQDMIGEDKNSFFMEPMSFRKNPTTEETVLTKTSLSLQEKKITQGKMSHLKKPLVLQKITSEEESFYKKLLPFKMKSTTEEKFLSQEPSALKEKHTTLQEVSLSKESLAIQEKATTEEEFSQELFSLHVKHTNKSGSLFQEALVLQEKTDAEEDSLKNLLALQEKSTMEEESLINKLLALKEELSAEAATNIQTQLSLKKKSTSHGKVFFLKKQLALNETINEEEFLNKQPLALEGYPSIAEGETLFKKLLAMQEEPSIEKEAVLKEPTIDTEAHFKEPLALQEEPSTEKEAVLKEPSVDTEAHFKETLALQEKPSIEQEALFKRHSALWEKPSTEKETIFKESLDLQEKPSIKKETLLKKPLALKMSTINEAVLFEDMIALNEKPTTGKELSFKEPLALQESPTYKEDTFLKTLLVPQVGTSPNVSSTAPESITSKSSIATMTSVGKSGTINEAFLFEDMITLNEKPTTGKELSFKEPLALQESPTCKEDTFLETFLIPQIGTSPYVFSTTPESITEKSSIATMTSVGKSRTTTESSACESASDKPVSPQAKGTPKEITPREDIDEDSSDPSFNPMYAKEIFSYMKEREEQFILTDYMNRQIEITSDMRAILVDWLVEVQVSFEMTHETLYLAVKLVDLYLMKAVCKKDKLQLLGATAFMIAAKFEEHNSPRVDDFVYICDDNYQRSEVLSMEINILNVLKCDINIPIAYHFLRRYARCIHTNMKTLTLSRYICEMTLQEYHYVQEKASKLAAASLLLALYMKKLGYWVPFLEHYSGYSISELHPLVRQLNKLLTFSSYDSLKAVYYKYSHPVFFEVAKIPALDMLKLEEILNCDCEAQGLVL | Homo sapiens | Nucleus | Group enriched (brain, epididymis, testis) | {'Ciliated cells': '0.9', 'Basal respiratory cells': '0.2', 'Club cells': '0.4', 'Ionocytes': '0.0', 'Mucus glandular cells': '0.5', 'Serous glandular cells': '0.1', 'Gastric mucus-secreting cells': '2.9', 'Proximal enterocytes': '0.0', 'Paneth cells': '0.1', 'Distal enterocytes': '0.0', 'Intestinal goblet cells': '0.4', 'Exocrine glandular cells': '-0.247', 'Basal prostatic cells': '0.2', 'Prostatic glandular cells': '0.0', 'Breast glandular cells': '0.201', 'Breast myoepithelial cells': '0.058', 'Glandular and luminal cells': '0.2', 'Secretory cells': '0.1', 'Basal keratinocytes': '0.2', 'Suprabasal keratinocytes': '0.1', 'Basal squamous epithelial cells': '0.2', 'Squamous epithelial cells': '0.4', 'Alveolar cells type 1': '0.270', 'Alveolar cells type 2': '0.293', 'Salivary duct cells': '0.2', 'Ductal cells': '0.277', 'Hepatocytes': '0.301', 'Cholangiocytes': '0.0', 'Proximal tubular cells': '0.065', 'Distal tubular cells': '0.0', 'Collecting duct cells': '0.0', 'Mesothelial cells': '-0.058', 'Sertoli cells': '0.229', 'Granulosa cells': '0.3', 'Enteroendocrine cells': '0.0', 'Pancreatic endocrine cells': '0.0', 'Leydig cells': '0.231', 'Excitatory neurons': '0.5', 'Inhibitory neurons': '0.4', 'Cone photoreceptor cells': '0.0', 'Rod photoreceptor cells': '0.7', 'Bipolar cells': '1.2', 'Horizontal cells': '0.6', 'Astrocytes': '1.5', 'Oligodendrocyte precursor cells': '0.0', 'Oligodendrocytes': '8.5', 'Microglial cells': '1.8', 'Muller glia cells': '0.3', 'Schwann cells': '0.077', 'Spermatogonia': '0.533', 'Spermatocytes': '0.778', 'Early spermatids': '-0.144', 'Late spermatids': '-0.237', 'Oocytes': '8.1', 'Cytotrophoblasts': '0.0', 'Syncytiotrophoblasts': '0.0', 'Extravillous trophoblasts': '0.0', 'Endothelial cells': '0.2', 'Lymphatic endothelial cells': '0.1', 'Cardiomyocytes': '0.526', 'Skeletal myocytes': '-0.196', 'Smooth muscle cells': '0.2', 'Adipocytes': '0.0', 'Melanocytes': '0.162', 'Fibroblasts': '0.0', 'Peritubular cells': '0.085', 'Endometrial stromal cells': '0.2', 'Ovarian stromal cells': '0.0', 'Undifferentiated cells': '0.1', 'T-cells': '0.3', 'B-cells': '0.2', 'Plasma cells': '0.2', 'Nk-cells': '2.3', 'Granulocytes': '0.0', 'Monocytes': '0.4', 'Macrophages': '0.6', 'Hofbauer cells': '0.1', 'Kupffer cells': '1.5', 'Dendritic cells': '0.0', 'Langerhans cells': '0.250', 'Erythroid cells': '0.000', 'Adipocytes (Subcutaneous)': '0.554', 'Adipocytes (Visceral)': '0.503', 'Breast glandular cells (progenitors)': '0.078', 'Adipocytes (Breast)': '0.072', 'Colon enterocytes': '0.084', 'Colon enteroendocrine cells': '0.103', 'Enteric glia cells': '-0.216', 'Mitotic cells (Colon)': '0.093', 'Mitotic cells (Heart)': '0.369', 'Podocytes': '-0.112', 'Ascending Loop of Henle cells': '0.590', 'Intercalated cells': '0.072', 'Cholangiocyte': '0.135', 'NK-cells (Liver)': '-0.139', 'Respiratory ciliated cells': '0.022', 'Mitotic cells (Lung)': '-0.010', 'NK-cells (Lung)': '0.011', 'B-cells (Lung)': '-0.202', 'Alpha cells': '0.248', 'Beta cells': '0.114', 'Prostate glandular cells': '0.230', 'Prostate basal glandular cells': '0.467', 'Urothelial cells': '0.284', 'Keratinocyte (other)': '0.301', 'Keratinocyte (granular)': '0.152', 'Hair cortex cells': '-0.150', 'Inner root sheath cells': '-0.155', 'Outer root sheath cells': '-0.105', 'Sebaceous gland cells': '0.089', 'Eccrine sweat gland cells': '-0.011', 'Adipocytes (Skin)': '-0.073', 'Mitotic cells (Skin)': '0.253', 'Parietal cells': '0.714', 'Chief cells': '0.612', 'Gastric mucous cells': '0.649', 'Gastric enteroendocrine cells': '0.526', 'Mitotic cells (Stomach)': '0.315', 'Parafollicular cells': '0.108', 'Thyroid glandular cells': '0.488', 'Mitotic cells (Thyroid)': '-0.031', 'Adrenal cortex cells': '0.631', 'Adrenal medulla cells': '0.069', 'Mitotic cells (Adrenal gland)': '0.468', 'Minor salivary glandular cells': '0.391', 'Minor salivary gland ductal cells': '0.082', 'Minor salivary gland basal cells': '0.190', 'Mitotic cells (Minor salivary gland)': '0.326', 'Adipocytes (Minor salivary gland)': '0.113', 'Somatotropes': '0.594', 'Lactotropes': '0.231', 'Gonadotropes': '0.061', 'Corticotropes': '0.159', 'Thyrotropes': '0.053', 'Undifferentiated cells (Pituitary gland)': '-0.347', 'Mitotic cells (Spleen)': '-0.069', 'Platelets': '0.181', 'Erythrocytes': '-0.174', 'Hematopoietic stem cells': '-0.001', 'B-cells (Spleen)': '0.120', 'NK-cells (Spleen)': '0.080', 'Amygdala excitatory': '1.4', 'Cerebellar inhibitory': '0.7', 'Cge interneuron': '0.7', 'Deep-layer corticothalamic and 6b': '1.6', 'Deep-layer intratelencephalic': '1.6', 'Deep-layer near-projecting': '3.1', 'Eccentric medium spiny neuron': '2.3', 'Hippocampal ca1-3': '0.8', 'Hippocampal ca4': '1.1', 'Hippocampal dentate gyrus': '0.7', 'Lamp5-lhx6 and chandelier': '0.3', 'Lower rhombic lip': '2.9', 'Mammillary body': '3.1', 'Medium spiny neuron': '0.7', 'Mge interneuron': '1.1', 'Midbrain-derived inhibitory': '5.4', 'Miscellaneous': '0.7', 'Splatter': '2.0', 'Thalamic excitatory': '3.0', 'Upper rhombic lip': '0.6', 'Upper-layer intratelencephalic': '0.9', 'Astrocyte': '3.2', 'Bergmann glia': '5.3', 'Central nervous system macrophage': '3.4', 'Choroid plexus epithelial cell': '1.2', 'Committed oligodendrocyte precursor': '5.3', 'Ependymal cell': '2.6', 'Oligodendrocyte': '17.7', 'Oligodendrocyte precursor cell': '2.5', 'Endothelial cell': '0.7', 'Pericyte': '0.5', 'Vascular associated smooth muscle cell': '0.0', 'Fibroblast': '0.6', 'Leukocyte': '1.6', 'Basophil': '0.0', 'Eosinophil': '0.0', 'Neutrophil': '0.0', 'Classical monocyte': '0.1', 'Non-classical monocyte': '0.6', 'Intermediate monocyte': '0.8', 'T-reg': '0.1', 'GdT-cell': '0.3', 'MAIT T-cell': '0.0', 'Memory CD4 T-cell': '0.0', 'Naive CD4 T-cell': '0.4', 'Memory CD8 T-cell': '0.0', 'Naive CD8 T-cell': '0.4', 'Memory B-cell': '0.0', 'Naive B-cell': '1.0', 'Plasmacytoid DC': '0.1', 'Myeloid DC': '0.7', 'NK-cell': '4.0', 'Total PBMC': '0.4', 'Vd2 gdTCR': '0.3', 'Memory CD4 T-cell Th1\\/Th17': '0.2', 'Memory CD4 T-cell Th17': '0.1', 'Memory CD4 T-cell Th2': '0.2', 'Non-Vd2 gdTCR': '1.7', 'Memory CD4 T-cell Th1': '0.2', 'Memory CD4 T-cell TFH': '0.2', 'Terminal effector memory CD4 T-cell': '0.0', 'Central memory CD8 T-cell': '0.2', 'Effector memory CD8 T-cell': '0.2', 'Terminal effector memory CD8 T-cell': '0.9', 'Non-switched memory B-cell': '0.0', 'Plasmablast': '0.0', 'Switched memory B-cell': '0.1', 'Exhausted memory B-cell': '0.0', 'Progenitor cell': '0.0', 'Memory T-reg': '0.0', 'Naive CD4 T-cell activated': '0.1', 'Naive CD8 T-cell activated': '0.1', 'Naive T-reg': '0.3'} | null | {'Adipose Tissue': 0.282478803986711, 'Adrenal Gland': 0.3962261240310077, 'Bladder': 0.2156395238095238, 'Blood': 0.0980808622174381, 'Blood Vessel': 0.1151695348314606, 'Brain': 0.4247745836487509, 'Breast': 0.3126401742919389, 'Cervix Uteri': 0.1514942105263158, 'Colon': 0.147873568677792, 'Esophagus': 0.1322234712802768, 'Fallopian 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0.29, 0.01, 0.0, 0.47, 0.12, 0.13, 0.59, 0.77, 0.21, 0.58, 0.29, 0.74, 0.82, 0.23, 0.29, 0.13, 0.0, 0.27, 0.61, 0.07, 0.0, 0.16, 0.55, 0.65, 0.6, 0.23, 0.36, 0.33, 0.0, 0.09, 0.52, 0.26, 0.83, 0.33, 0.18, 0.54, 0.29, 0.69, 0.56, 0.0, 0.29, 0.56, 0.3, 0.0, 0.51, 0.57, 0.23, 0.4, 0.65, 0.47, 0.34, 0.65, 0.85, 0.75, 0.87] | null | Component of an E-cadherin/ catenin adhesion complex composed of at least E-cadherin/CDH1, beta-catenin/CTNNB1 or gamma-catenin/JUP, and potentially alpha-catenin/CTNNA1. Forms a ternary complex composed of ADAM10, CADH1 and EPHA4, | null | null | KLRG1, SPEF1, DLGAP5, AJAP1, RAPGEF2, RAB8B, PIP5K1C, PKP2, TRPV4, CTNNB1, CAV1, DDR1, TBC1D2, CTNNA1, JUP, CTNND1, PSEN1, LIMA1, CDH1, JUP, ADAM10, CADH1 , EPHA4, | null | null | null | null | Homodimer | null | 79.91949 | 0.474025 | 41.688989 | 0.802093 | 235 |
P12830 | Q969U6 | null | degron_data | CDH1 | MGPWSRSLSALLLLLQVSSWLCQEPEPCHPGFDAESYTFTVPRRHLERGRVLGRVNFEDCTGRQRTAYFSLDTRFKVGTDGVITVKRPLRFHNPQIHFLVYAWDSTYRKFSTKVTLNTVGHHHRPPPHQASVSGIQAELLTFPNSSPGLRRQKRDWVIPPISCPENEKGPFPKNLVQIKSNKDKEGKVFYSITGQGADTPPVGVFIIERETGWLKVTEPLDRERIATYTLFSHAVSSNGNAVEDPMEILITVTDQNDNKPEFTQEVFKGSVMEGALPGTSVMEVTATDADDDVNTYNAAIAYTILSQDPELPDKNMFTINRNTGVISVVTTGLDRESFPTYTLVVQAADLQGEGLSTTATAVITVTDTNDNPPIFNPTTYKGQVPENEANVVITTLKVTDADAPNTPAWEAVYTILNDDGGQFVVTTNPVNNDGILKTAKGLDFEAKQQYILHVAVTNVVPFEVSLTTSTATVTVDVLDVNEAPIFVPPEKRVEVSEDFGVGQEITSYTAQEPDTFMEQKITYRIWRDTANWLEINPDTGAISTRAELDREDFEHVKNSTYTALIIATDNGSPVATGTGTLLLILSDVNDNAPIPEPRTIFFCERNPKPQVINIIDADLPPNTSPFTAELTHGASANWTIQYNDPTQESIILKPKMALEVGDYKINLKLMDNQNKDQVTTLEVSVCDCEGAAGVCRKAQPVEAGLQIPAILGILGGILALLILILLLLLFLRRRAVVKEPLLPPEDDTRDNVYYYDEEGGGEEDQDFDLSQLHRGLDARPEVTRNDVAPTLMSVPRYLPRPANPDEIGNFIDENLKAADTDPTAPPYDSLLVFDYEGSGSEAASLSSLNSSESDKDQDYDYLNEWGNRFKKLADMYGGGEDD | Homo sapiens | Cell junction, adherens junction, Cell membrane, Endosome, Golgi apparatus, trans-Golgi network, Cytoplasm, Cell junction, desmosome | Tissue enhanced (parathyroid) | {'Ciliated cells': '119.1', 'Basal respiratory cells': '71.1', 'Club cells': '97.3', 'Ionocytes': '81.0', 'Mucus glandular cells': '155.0', 'Serous glandular cells': '67.8', 'Gastric mucus-secreting cells': '133.2', 'Proximal enterocytes': '140.9', 'Paneth cells': '125.1', 'Distal enterocytes': '307.5', 'Intestinal goblet cells': '173.5', 'Exocrine glandular cells': '-0.605', 'Basal prostatic cells': '68.3', 'Prostatic glandular cells': '186.7', 'Breast glandular cells': '0.773', 'Breast myoepithelial cells': '0.700', 'Glandular and luminal cells': '313.0', 'Secretory cells': '82.3', 'Basal keratinocytes': '102.5', 'Suprabasal keratinocytes': '162.6', 'Basal squamous epithelial cells': '51.0', 'Squamous epithelial cells': '106.9', 'Alveolar cells type 1': '0.437', 'Alveolar cells type 2': '0.706', 'Salivary duct cells': '95.9', 'Ductal cells': '0.541', 'Hepatocytes': '0.600', 'Cholangiocytes': '129.7', 'Proximal tubular cells': '0.042', 'Distal tubular cells': '0.0', 'Collecting duct cells': '143.9', 'Mesothelial cells': '0.799', 'Sertoli cells': '0.252', 'Granulosa cells': '12.9', 'Enteroendocrine cells': '92.4', 'Pancreatic endocrine cells': '78.1', 'Leydig cells': '0.264', 'Excitatory neurons': '0.7', 'Inhibitory neurons': '1.3', 'Cone photoreceptor cells': '0.0', 'Rod photoreceptor cells': '0.0', 'Bipolar cells': '0.2', 'Horizontal cells': '0.6', 'Astrocytes': '0.6', 'Oligodendrocyte precursor cells': '0.5', 'Oligodendrocytes': '29.9', 'Microglial cells': '0.9', 'Muller glia cells': '0.1', 'Schwann cells': '0.131', 'Spermatogonia': '0.392', 'Spermatocytes': '0.193', 'Early spermatids': '-0.217', 'Late spermatids': '-0.290', 'Oocytes': '16.9', 'Cytotrophoblasts': '119.2', 'Syncytiotrophoblasts': '45.0', 'Extravillous trophoblasts': '24.9', 'Endothelial cells': '6.1', 'Lymphatic endothelial cells': '0.4', 'Cardiomyocytes': '0.135', 'Skeletal myocytes': '0.107', 'Smooth muscle cells': '5.8', 'Adipocytes': '2.1', 'Melanocytes': '0.335', 'Fibroblasts': '6.5', 'Peritubular cells': '0.210', 'Endometrial stromal cells': '27.7', 'Ovarian stromal cells': '0.7', 'Undifferentiated cells': '101.6', 'T-cells': '2.9', 'B-cells': '4.4', 'Plasma cells': '6.1', 'Nk-cells': '0.0', 'Granulocytes': '8.4', 'Monocytes': '0.0', 'Macrophages': '6.0', 'Hofbauer cells': '4.3', 'Kupffer cells': '1.0', 'Dendritic cells': '5.9', 'Langerhans cells': '0.304', 'Erythroid cells': '0.036', 'Adipocytes (Subcutaneous)': '-0.081', 'Adipocytes (Visceral)': '-0.209', 'Breast glandular cells (progenitors)': '0.538', 'Adipocytes (Breast)': '-0.689', 'Colon enterocytes': '0.790', 'Colon enteroendocrine cells': '0.112', 'Enteric glia cells': '-0.048', 'Mitotic cells (Colon)': '0.299', 'Mitotic cells (Heart)': '0.120', 'Podocytes': '-0.118', 'Ascending Loop of Henle cells': '0.475', 'Intercalated cells': '0.212', 'Cholangiocyte': '0.090', 'NK-cells (Liver)': '-0.005', 'Respiratory ciliated cells': '-0.012', 'Mitotic cells (Lung)': '0.071', 'NK-cells (Lung)': '-0.266', 'B-cells (Lung)': '-0.296', 'Alpha cells': '0.270', 'Beta cells': '0.152', 'Prostate glandular cells': '0.764', 'Prostate basal glandular cells': '0.540', 'Urothelial cells': '0.205', 'Keratinocyte (other)': '0.510', 'Keratinocyte (granular)': '0.055', 'Hair cortex cells': '0.080', 'Inner root sheath cells': '0.131', 'Outer root sheath cells': '0.175', 'Sebaceous gland cells': '0.156', 'Eccrine sweat gland cells': '-0.207', 'Adipocytes (Skin)': '-0.244', 'Mitotic cells (Skin)': '0.442', 'Parietal cells': '0.654', 'Chief cells': '0.649', 'Gastric mucous cells': '0.781', 'Gastric enteroendocrine cells': '0.590', 'Mitotic cells (Stomach)': '0.445', 'Parafollicular cells': '0.173', 'Thyroid glandular cells': '0.865', 'Mitotic cells (Thyroid)': '-0.081', 'Adrenal cortex cells': '0.051', 'Adrenal medulla cells': '0.087', 'Mitotic cells (Adrenal gland)': '0.072', 'Minor salivary glandular cells': '0.371', 'Minor salivary gland ductal cells': '-0.142', 'Minor salivary gland basal cells': '0.582', 'Mitotic cells (Minor salivary gland)': '0.567', 'Adipocytes (Minor salivary gland)': '0.050', 'Somatotropes': '0.121', 'Lactotropes': '0.322', 'Gonadotropes': '0.330', 'Corticotropes': '0.180', 'Thyrotropes': '0.496', 'Undifferentiated cells (Pituitary gland)': '-0.108', 'Mitotic cells (Spleen)': '-0.228', 'Platelets': '-0.050', 'Erythrocytes': '-0.158', 'Hematopoietic stem cells': '-0.211', 'B-cells (Spleen)': '0.266', 'NK-cells (Spleen)': '0.309', 'Amygdala excitatory': '1.0', 'Cerebellar inhibitory': '0.9', 'Cge interneuron': '0.7', 'Deep-layer corticothalamic and 6b': '1.5', 'Deep-layer intratelencephalic': '0.7', 'Deep-layer near-projecting': '0.7', 'Eccentric medium spiny neuron': '0.6', 'Hippocampal ca1-3': '1.9', 'Hippocampal ca4': '1.2', 'Hippocampal dentate gyrus': '1.1', 'Lamp5-lhx6 and chandelier': '0.5', 'Lower rhombic lip': '0.8', 'Mammillary body': '0.6', 'Medium spiny neuron': '0.7', 'Mge interneuron': '1.7', 'Midbrain-derived inhibitory': '0.7', 'Miscellaneous': '0.9', 'Splatter': '3.8', 'Thalamic excitatory': '0.5', 'Upper rhombic lip': '0.8', 'Upper-layer intratelencephalic': '0.6', 'Astrocyte': '4.4', 'Bergmann glia': '0.2', 'Central nervous system macrophage': '0.6', 'Choroid plexus epithelial cell': '52.1', 'Committed oligodendrocyte precursor': '41.5', 'Ependymal cell': '4.8', 'Oligodendrocyte': '53.1', 'Oligodendrocyte precursor cell': '2.4', 'Endothelial cell': '0.7', 'Pericyte': '0.3', 'Vascular associated smooth muscle cell': '0.0', 'Fibroblast': '17.4', 'Leukocyte': '1.1', 'Basophil': '0.0', 'Eosinophil': '0.0', 'Neutrophil': '0.0', 'Classical monocyte': '0.0', 'Non-classical monocyte': '0.0', 'Intermediate monocyte': '0.0', 'T-reg': '2.3', 'GdT-cell': '0.0', 'MAIT T-cell': '0.0', 'Memory CD4 T-cell': '0.0', 'Naive CD4 T-cell': '0.1', 'Memory CD8 T-cell': '0.2', 'Naive CD8 T-cell': '0.3', 'Memory B-cell': '0.0', 'Naive B-cell': '0.1', 'Plasmacytoid DC': '46.6', 'Myeloid DC': '8.5', 'NK-cell': '0.1', 'Total PBMC': '0.7', 'Vd2 gdTCR': '0.0', 'Memory CD4 T-cell Th1\\/Th17': '0.1', 'Memory CD4 T-cell Th17': '0.2', 'Memory CD4 T-cell Th2': '2.9', 'Non-Vd2 gdTCR': '0.1', 'Memory CD4 T-cell Th1': '0.3', 'Memory CD4 T-cell TFH': '0.5', 'Terminal effector memory CD4 T-cell': '0.0', 'Central memory CD8 T-cell': '4.8', 'Effector memory CD8 T-cell': '0.0', 'Terminal effector memory CD8 T-cell': '0.6', 'Non-switched memory B-cell': '0.0', 'Plasmablast': '3.3', 'Switched memory B-cell': '0.0', 'Exhausted memory B-cell': '0.7', 'Progenitor cell': '2.3', 'Memory T-reg': '1.3', 'Naive CD4 T-cell activated': '0.3', 'Naive CD8 T-cell activated': '0.6', 'Naive T-reg': '0.1'} | 1O6S, 2O72, 2OMT, 2OMU, 2OMV, 2OMX, 2OMY, 2OMZ, 3FF7, 3FF8, 3L6X, 3L6Y, 4ZT1, 4ZTE, 6CXY, 6OLE, 6OLF, 6OLG, 6VEL, 7STZ, 8H62 | {'Adipose Tissue': 1.2125261088039867, 'Adrenal Gland': 0.1914223992248062, 'Bladder': 39.2033519047619, 'Blood': 1.340954264800861, 'Blood Vessel': 0.3121561692883895, 'Brain': 0.8550442199091597, 'Breast': 38.54918344226579, 'Cervix Uteri': 23.539115789473684, 'Colon': 43.41292142490372, 'Esophagus': 53.97513367404844, 'Fallopian Tube': 14.900277777777776, 'Heart': 0.119140469221835, 'Kidney': 25.040449438202245, 'Liver': 26.60802654867257, 'Lung': 35.447986366782004, 'Muscle': 0.1378936151930261, 'Nerve': 17.518468982229404, 'Ovary': 3.6515122222222223, 'Pancreas': 56.89676829268293, 'Pituitary': 24.68741660777385, 'Prostate': 61.279967346938776, 'Salivary Gland': 92.01685185185184, 'Skin': 79.77571720232172, 'Small Intestine': 71.7519320855615, 'Spleen': 10.061029045643156, 'Stomach': 58.07813805013927, 'Testis': 0.8144204986149585, 'Thyroid': 135.176797856049, 'Uterus': 1.442593943661972, 'Vagina': 86.52345512820513} | FBXW5 | MDEGGTPLLPDSLVYQIFLSLGPADVLAAGLVCRQWQAVSRDEFLWREQFYRYYQVARDVPRHPAAMSWYEEFQRLYDTVPCVEVQTLREHTDQVLHLSFSHSGYQFASCSKDCTVKIWSNDLTISLLHSADMRPYNWSYTQFSQFNKDDSLLLASGVFLGPHNSSSGEIAVISLDSFALLSRVRNKPYDVFGCWLTETSLISGNLHRIGDITSCSVLWLNNAFQDVESENVNVVKRLFKIQNLNASTVRTVMVADCSRFDSPDLLLEAGDPATSPCRIFDLGSDNEEVVAGPAPAHAKEGLRHFLDRVLEGRAQPQLSERMLETKVAELLAQGHTKPPERSATGAKSKYLIFTTGCLTYSPHQIGIKQILPHQMTTAGPVLGEGRGSDAFFDALDHVIDIHGHIIGMGLSPDNRYLYVNSRAWPNGAVVADPMQPPPIAEEIDLLVFDLKTMREVRRALRAHRAYTPNDECFFIFLDVSRDFVASGAEDRHGYIWDRHYNICLARLRHEDVVNSVVFSPQEQELLLTASDDATIKAWRSPRTMRVLQAPRPRPRTFFSWLASQRR | Homo sapiens | Cytoplasm | Tissue enhanced (testis) | {'Ciliated cells': '44.0', 'Basal respiratory cells': '123.6', 'Club cells': '78.2', 'Ionocytes': '93.1', 'Mucus glandular cells': '87.3', 'Serous glandular cells': '126.5', 'Gastric mucus-secreting cells': '86.7', 'Proximal enterocytes': '428.3', 'Paneth cells': '161.9', 'Distal enterocytes': '300.2', 'Intestinal goblet cells': '119.7', 'Exocrine glandular cells': '-0.709', 'Basal prostatic cells': '30.1', 'Prostatic glandular cells': '48.0', 'Breast glandular cells': '-0.282', 'Breast myoepithelial cells': '-0.420', 'Glandular and luminal cells': '41.0', 'Secretory cells': '43.9', 'Basal keratinocytes': '50.5', 'Suprabasal keratinocytes': '96.8', 'Basal squamous epithelial cells': '28.8', 'Squamous epithelial cells': '50.4', 'Alveolar cells type 1': '-0.116', 'Alveolar cells type 2': '-0.146', 'Salivary duct cells': '55.7', 'Ductal cells': '0.482', 'Hepatocytes': '0.041', 'Cholangiocytes': '49.6', 'Proximal tubular cells': '0.224', 'Distal tubular cells': '61.5', 'Collecting duct cells': '23.3', 'Mesothelial cells': '-0.052', 'Sertoli cells': '-0.545', 'Granulosa cells': '31.7', 'Enteroendocrine cells': '78.9', 'Pancreatic endocrine cells': '83.2', 'Leydig cells': '-0.618', 'Excitatory neurons': '15.4', 'Inhibitory neurons': '14.7', 'Cone photoreceptor cells': '23.8', 'Rod photoreceptor cells': '30.7', 'Bipolar cells': '26.0', 'Horizontal cells': '49.1', 'Astrocytes': '12.4', 'Oligodendrocyte precursor cells': '10.4', 'Oligodendrocytes': '15.9', 'Microglial cells': '8.1', 'Muller glia cells': '53.7', 'Schwann cells': '-0.051', 'Spermatogonia': '-0.326', 'Spermatocytes': '0.015', 'Early spermatids': '0.655', 'Late spermatids': '0.755', 'Oocytes': '6.6', 'Cytotrophoblasts': '69.6', 'Syncytiotrophoblasts': '118.5', 'Extravillous trophoblasts': '145.8', 'Endothelial cells': '51.2', 'Lymphatic endothelial cells': '36.8', 'Cardiomyocytes': '0.636', 'Skeletal myocytes': '-0.181', 'Smooth muscle cells': '65.1', 'Adipocytes': '60.0', 'Melanocytes': '-0.067', 'Fibroblasts': '46.0', 'Peritubular cells': '-0.469', 'Endometrial stromal cells': '28.0', 'Ovarian stromal cells': '32.2', 'Undifferentiated cells': '75.3', 'T-cells': '60.1', 'B-cells': '35.8', 'Plasma cells': '64.2', 'Nk-cells': '78.3', 'Granulocytes': '39.8', 'Monocytes': '67.9', 'Macrophages': '65.5', 'Hofbauer cells': '86.3', 'Kupffer cells': '52.2', 'Dendritic cells': '107.0', 'Langerhans cells': '0.289', 'Erythroid cells': '0.022', 'Adipocytes (Subcutaneous)': '0.367', 'Adipocytes (Visceral)': '0.428', 'Breast glandular cells (progenitors)': '-0.215', 'Adipocytes (Breast)': '0.544', 'Colon enterocytes': '-0.227', 'Colon enteroendocrine cells': '0.049', 'Enteric glia cells': '0.280', 'Mitotic cells (Colon)': '-0.186', 'Mitotic cells (Heart)': '0.470', 'Podocytes': '-0.140', 'Ascending Loop of Henle cells': '0.434', 'Intercalated cells': '-0.119', 'Cholangiocyte': '0.254', 'NK-cells (Liver)': '-0.268', 'Respiratory ciliated cells': '0.010', 'Mitotic cells (Lung)': '0.133', 'NK-cells (Lung)': '-0.082', 'B-cells (Lung)': '-0.110', 'Alpha cells': '0.363', 'Beta cells': '0.195', 'Prostate glandular cells': '-0.030', 'Prostate basal glandular cells': '0.018', 'Urothelial cells': '0.051', 'Keratinocyte (other)': '0.115', 'Keratinocyte (granular)': '0.151', 'Hair cortex cells': '-0.185', 'Inner root sheath cells': '-0.227', 'Outer root sheath cells': '-0.103', 'Sebaceous gland cells': '0.016', 'Eccrine sweat gland cells': '-0.264', 'Adipocytes (Skin)': '-0.067', 'Mitotic cells (Skin)': '-0.030', 'Parietal cells': '-0.701', 'Chief cells': '-0.510', 'Gastric mucous cells': '-0.377', 'Gastric enteroendocrine cells': '-0.411', 'Mitotic cells (Stomach)': '0.041', 'Parafollicular cells': '0.002', 'Thyroid glandular cells': '0.097', 'Mitotic cells (Thyroid)': '0.017', 'Adrenal cortex cells': '0.552', 'Adrenal medulla cells': '-0.003', 'Mitotic cells (Adrenal gland)': '-0.180', 'Minor salivary glandular cells': '0.369', 'Minor salivary gland ductal cells': '-0.214', 'Minor salivary gland basal cells': '0.212', 'Mitotic cells (Minor salivary gland)': '0.341', 'Adipocytes (Minor salivary gland)': '0.102', 'Somatotropes': '0.250', 'Lactotropes': '0.141', 'Gonadotropes': '0.038', 'Corticotropes': '-0.007', 'Thyrotropes': '0.021', 'Undifferentiated cells (Pituitary gland)': '-0.125', 'Mitotic cells (Spleen)': '-0.398', 'Platelets': '-0.155', 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0.71, 0.56, 0.06, 0.78, 0.45, 0.26, 0.0, 0.14, 0.07, 0.04, 0.1, 0.1, 0.02, 0.45, 0.3, 0.06, 0.71, 0.28, 0.0, 0.0, 0.0, 0.0, 0.0, 0.37, 0.07, 0.09, 0.1, 0.02, 0.08, 0.01, 0.01, 0.12, 0.1, 0.58, 0.61, 0.72, 0.08, 0.46, 0.39, 0.44, 0.27, 0.47, 0.14, 0.42, 0.02, 0.55, 0.79, 0.37, 0.61, 0.04, 0.37, 0.25, 0.0, 0.07, 0.14, 0.01, 0.33, 0.03, 0.0, 0.65, 0.57, 0.18, 0.3, 0.03, 0.0, 0.0, 0.0, 0.01, 0.01, 0.06, 0.25, 0.71, 0.74, 0.68, 0.97, 0.85, 0.27, 0.28, 0.26, 0.03, 0.08, 0.0, 0.0, 0.01, 0.03, 0.12, 0.08, 0.83, 0.68, 0.28, 0.39, 0.33, 0.35, 0.04, 0.4, 0.06, 0.84, 0.01, 0.4, 0.06, 0.2, 0.02, 0.02, 0.03, 0.0, 0.03, 0.09, 0.04, 0.32, 0.4, 0.43, 0.1, 0.0, 0.0, 0.03, 0.03, 0.36, 0.24, 0.42, 0.83, 0.55, 0.35, 0.77, 0.05, 0.08, 0.07, 0.03, 0.05, 0.05, 0.01, 0.32, 0.0, 0.04, 0.3, 0.0, 0.47, 0.38, 0.71, 0.74, 0.97, 0.17, 0.65, 0.99, 0.73, 0.38, 0.38, 0.44, 0.07, 0.18, 0.03, 0.03, 0.12, 0.08, 0.23, 0.03, 0.21, 0.12, 0.28, 0.02, 0.08, 0.01, 0.17, 0.14, 0.04, 0.18, 0.2, 0.0, 0.34, 0.06, 0.51, 0.62, 0.12, 0.79, 0.62, 0.29, 0.47, 0.03, 0.67, 0.11, 0.57, 0.8, 0.51, 0.73, 0.79, 0.84, 0.84, 0.7, 0.89, 0.77, 0.83, 0.88, 0.83, 0.84, 0.92, 0.77, 0.83, 0.91, 0.92, 0.88, 0.92, 0.9, 0.85, 0.91, 0.82, 0.81, 0.81, 0.76, 0.68, 0.54, 0.21, 0.59, 0.58, 0.35, 0.18, 0.7, 0.61, 0.18, 0.43, 0.4, 0.46, 0.31, 0.82, 0.59, 0.56, 0.68, 0.31, 0.88, 0.84, 0.93, 0.43, 0.49, 0.76, 0.48, 0.56, 0.3, 0.21, 0.08, 0.39, 0.24, 0.08, 0.35, 0.13, 0.35, 0.22, 0.67, 0.38, 0.25, 0.35, 0.43, 0.89, 0.44, 0.37, 0.93, 0.36, 0.84, 0.98, 0.97, 0.43, 0.73, 0.16, 0.2, 0.18, 0.0, 0.0, 0.0, 0.01, 0.12, 0.0, 0.39, 0.43, 0.0, 0.26, 0.02, 0.12, 0.0, 0.13, 0.0, 0.0, 0.0, 0.08, 0.13, 0.01, 0.1, 0.59, 0.62, 0.1, 0.21, 0.41, 0.25, 0.6, 0.81, 0.71, 0.6, 0.23, 0.41, 0.78, 0.93, 0.31, 0.6, 0.89, 0.49, 0.39, 0.5, 0.09, 0.13, 0.2, 0.25, 0.29, 0.52, 0.54, 0.09, 0.62, 0.07, 0.42, 0.0, 0.08, 0.05, 0.02, 0.12, 0.12, 0.1, 0.19, 0.01, 0.49, 0.03, 0.18, 0.08, 0.01, 0.0, 0.01, 0.0, 0.0, 0.02, 0.03, 0.29, 0.08, 0.5, 0.92, 0.82, 0.29, 0.82, 0.2, 0.84, 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Forms a ternary complex composed of ADAM10, CADH1 and EPHA4, | null | null | KLRG1, SPEF1, DLGAP5, AJAP1, RAPGEF2, RAB8B, PIP5K1C, PKP2, TRPV4, CTNNB1, CAV1, DDR1, TBC1D2, CTNNA1, JUP, CTNND1, PSEN1, LIMA1, CDH1, JUP, ADAM10, CADH1 , EPHA4, | null | null | null | null | Homodimer | null | 79.91949 | 0.474025 | 85.715777 | 0.339576 | 1,370 |
P12830 | Q96FF9 | null | degron_data | CDH1 | MGPWSRSLSALLLLLQVSSWLCQEPEPCHPGFDAESYTFTVPRRHLERGRVLGRVNFEDCTGRQRTAYFSLDTRFKVGTDGVITVKRPLRFHNPQIHFLVYAWDSTYRKFSTKVTLNTVGHHHRPPPHQASVSGIQAELLTFPNSSPGLRRQKRDWVIPPISCPENEKGPFPKNLVQIKSNKDKEGKVFYSITGQGADTPPVGVFIIERETGWLKVTEPLDRERIATYTLFSHAVSSNGNAVEDPMEILITVTDQNDNKPEFTQEVFKGSVMEGALPGTSVMEVTATDADDDVNTYNAAIAYTILSQDPELPDKNMFTINRNTGVISVVTTGLDRESFPTYTLVVQAADLQGEGLSTTATAVITVTDTNDNPPIFNPTTYKGQVPENEANVVITTLKVTDADAPNTPAWEAVYTILNDDGGQFVVTTNPVNNDGILKTAKGLDFEAKQQYILHVAVTNVVPFEVSLTTSTATVTVDVLDVNEAPIFVPPEKRVEVSEDFGVGQEITSYTAQEPDTFMEQKITYRIWRDTANWLEINPDTGAISTRAELDREDFEHVKNSTYTALIIATDNGSPVATGTGTLLLILSDVNDNAPIPEPRTIFFCERNPKPQVINIIDADLPPNTSPFTAELTHGASANWTIQYNDPTQESIILKPKMALEVGDYKINLKLMDNQNKDQVTTLEVSVCDCEGAAGVCRKAQPVEAGLQIPAILGILGGILALLILILLLLLFLRRRAVVKEPLLPPEDDTRDNVYYYDEEGGGEEDQDFDLSQLHRGLDARPEVTRNDVAPTLMSVPRYLPRPANPDEIGNFIDENLKAADTDPTAPPYDSLLVFDYEGSGSEAASLSSLNSSESDKDQDYDYLNEWGNRFKKLADMYGGGEDD | Homo sapiens | Cell junction, adherens junction, Cell membrane, Endosome, Golgi apparatus, trans-Golgi network, Cytoplasm, Cell junction, desmosome | Tissue enhanced (parathyroid) | {'Ciliated cells': '119.1', 'Basal respiratory cells': '71.1', 'Club cells': '97.3', 'Ionocytes': '81.0', 'Mucus glandular cells': '155.0', 'Serous glandular cells': '67.8', 'Gastric mucus-secreting cells': '133.2', 'Proximal enterocytes': '140.9', 'Paneth cells': '125.1', 'Distal enterocytes': '307.5', 'Intestinal goblet cells': '173.5', 'Exocrine glandular cells': '-0.605', 'Basal prostatic cells': '68.3', 'Prostatic glandular cells': '186.7', 'Breast glandular cells': '0.773', 'Breast myoepithelial cells': '0.700', 'Glandular and luminal cells': '313.0', 'Secretory cells': '82.3', 'Basal keratinocytes': '102.5', 'Suprabasal keratinocytes': '162.6', 'Basal squamous epithelial cells': '51.0', 'Squamous epithelial cells': '106.9', 'Alveolar cells type 1': '0.437', 'Alveolar cells type 2': '0.706', 'Salivary duct cells': '95.9', 'Ductal cells': '0.541', 'Hepatocytes': '0.600', 'Cholangiocytes': '129.7', 'Proximal tubular cells': '0.042', 'Distal tubular cells': '0.0', 'Collecting duct cells': '143.9', 'Mesothelial cells': '0.799', 'Sertoli cells': '0.252', 'Granulosa cells': '12.9', 'Enteroendocrine cells': '92.4', 'Pancreatic endocrine cells': '78.1', 'Leydig cells': '0.264', 'Excitatory neurons': '0.7', 'Inhibitory neurons': '1.3', 'Cone photoreceptor cells': '0.0', 'Rod photoreceptor cells': '0.0', 'Bipolar cells': '0.2', 'Horizontal cells': '0.6', 'Astrocytes': '0.6', 'Oligodendrocyte precursor cells': '0.5', 'Oligodendrocytes': '29.9', 'Microglial cells': '0.9', 'Muller glia cells': '0.1', 'Schwann cells': '0.131', 'Spermatogonia': '0.392', 'Spermatocytes': '0.193', 'Early spermatids': '-0.217', 'Late spermatids': '-0.290', 'Oocytes': '16.9', 'Cytotrophoblasts': '119.2', 'Syncytiotrophoblasts': '45.0', 'Extravillous trophoblasts': '24.9', 'Endothelial cells': '6.1', 'Lymphatic endothelial cells': '0.4', 'Cardiomyocytes': '0.135', 'Skeletal myocytes': '0.107', 'Smooth muscle cells': '5.8', 'Adipocytes': '2.1', 'Melanocytes': '0.335', 'Fibroblasts': '6.5', 'Peritubular cells': '0.210', 'Endometrial stromal cells': '27.7', 'Ovarian stromal cells': '0.7', 'Undifferentiated cells': '101.6', 'T-cells': '2.9', 'B-cells': '4.4', 'Plasma cells': '6.1', 'Nk-cells': '0.0', 'Granulocytes': '8.4', 'Monocytes': '0.0', 'Macrophages': '6.0', 'Hofbauer cells': '4.3', 'Kupffer cells': '1.0', 'Dendritic cells': '5.9', 'Langerhans cells': '0.304', 'Erythroid cells': '0.036', 'Adipocytes (Subcutaneous)': '-0.081', 'Adipocytes (Visceral)': '-0.209', 'Breast glandular cells (progenitors)': '0.538', 'Adipocytes (Breast)': '-0.689', 'Colon enterocytes': '0.790', 'Colon enteroendocrine cells': '0.112', 'Enteric glia cells': '-0.048', 'Mitotic cells (Colon)': '0.299', 'Mitotic cells (Heart)': '0.120', 'Podocytes': '-0.118', 'Ascending Loop of Henle cells': '0.475', 'Intercalated cells': '0.212', 'Cholangiocyte': '0.090', 'NK-cells (Liver)': '-0.005', 'Respiratory ciliated cells': '-0.012', 'Mitotic cells (Lung)': '0.071', 'NK-cells (Lung)': '-0.266', 'B-cells (Lung)': '-0.296', 'Alpha cells': '0.270', 'Beta cells': '0.152', 'Prostate glandular cells': '0.764', 'Prostate basal glandular cells': '0.540', 'Urothelial cells': '0.205', 'Keratinocyte (other)': '0.510', 'Keratinocyte (granular)': '0.055', 'Hair cortex cells': '0.080', 'Inner root sheath cells': '0.131', 'Outer root sheath cells': '0.175', 'Sebaceous gland cells': '0.156', 'Eccrine sweat gland cells': '-0.207', 'Adipocytes (Skin)': '-0.244', 'Mitotic cells (Skin)': '0.442', 'Parietal cells': '0.654', 'Chief cells': '0.649', 'Gastric mucous cells': '0.781', 'Gastric enteroendocrine cells': '0.590', 'Mitotic cells (Stomach)': '0.445', 'Parafollicular cells': '0.173', 'Thyroid glandular cells': '0.865', 'Mitotic cells (Thyroid)': '-0.081', 'Adrenal cortex cells': '0.051', 'Adrenal medulla cells': '0.087', 'Mitotic cells (Adrenal gland)': '0.072', 'Minor salivary glandular cells': '0.371', 'Minor salivary gland ductal cells': '-0.142', 'Minor salivary gland basal cells': '0.582', 'Mitotic cells (Minor salivary gland)': '0.567', 'Adipocytes (Minor salivary gland)': '0.050', 'Somatotropes': '0.121', 'Lactotropes': '0.322', 'Gonadotropes': '0.330', 'Corticotropes': '0.180', 'Thyrotropes': '0.496', 'Undifferentiated cells (Pituitary gland)': '-0.108', 'Mitotic cells (Spleen)': '-0.228', 'Platelets': '-0.050', 'Erythrocytes': '-0.158', 'Hematopoietic stem cells': '-0.211', 'B-cells (Spleen)': '0.266', 'NK-cells (Spleen)': '0.309', 'Amygdala excitatory': '1.0', 'Cerebellar inhibitory': '0.9', 'Cge interneuron': '0.7', 'Deep-layer corticothalamic and 6b': '1.5', 'Deep-layer intratelencephalic': '0.7', 'Deep-layer near-projecting': '0.7', 'Eccentric medium spiny neuron': '0.6', 'Hippocampal ca1-3': '1.9', 'Hippocampal ca4': '1.2', 'Hippocampal dentate gyrus': '1.1', 'Lamp5-lhx6 and chandelier': '0.5', 'Lower rhombic lip': '0.8', 'Mammillary body': '0.6', 'Medium spiny neuron': '0.7', 'Mge interneuron': '1.7', 'Midbrain-derived inhibitory': '0.7', 'Miscellaneous': '0.9', 'Splatter': '3.8', 'Thalamic excitatory': '0.5', 'Upper rhombic lip': '0.8', 'Upper-layer intratelencephalic': '0.6', 'Astrocyte': '4.4', 'Bergmann glia': '0.2', 'Central nervous system macrophage': '0.6', 'Choroid plexus epithelial cell': '52.1', 'Committed oligodendrocyte precursor': '41.5', 'Ependymal cell': '4.8', 'Oligodendrocyte': '53.1', 'Oligodendrocyte precursor cell': '2.4', 'Endothelial cell': '0.7', 'Pericyte': '0.3', 'Vascular associated smooth muscle cell': '0.0', 'Fibroblast': '17.4', 'Leukocyte': '1.1', 'Basophil': '0.0', 'Eosinophil': '0.0', 'Neutrophil': '0.0', 'Classical monocyte': '0.0', 'Non-classical monocyte': '0.0', 'Intermediate monocyte': '0.0', 'T-reg': '2.3', 'GdT-cell': '0.0', 'MAIT T-cell': '0.0', 'Memory CD4 T-cell': '0.0', 'Naive CD4 T-cell': '0.1', 'Memory CD8 T-cell': '0.2', 'Naive CD8 T-cell': '0.3', 'Memory B-cell': '0.0', 'Naive B-cell': '0.1', 'Plasmacytoid DC': '46.6', 'Myeloid DC': '8.5', 'NK-cell': '0.1', 'Total PBMC': '0.7', 'Vd2 gdTCR': '0.0', 'Memory CD4 T-cell Th1\\/Th17': '0.1', 'Memory CD4 T-cell Th17': '0.2', 'Memory CD4 T-cell Th2': '2.9', 'Non-Vd2 gdTCR': '0.1', 'Memory CD4 T-cell Th1': '0.3', 'Memory CD4 T-cell TFH': '0.5', 'Terminal effector memory CD4 T-cell': '0.0', 'Central memory CD8 T-cell': '4.8', 'Effector memory CD8 T-cell': '0.0', 'Terminal effector memory CD8 T-cell': '0.6', 'Non-switched memory B-cell': '0.0', 'Plasmablast': '3.3', 'Switched memory B-cell': '0.0', 'Exhausted memory B-cell': '0.7', 'Progenitor cell': '2.3', 'Memory T-reg': '1.3', 'Naive CD4 T-cell activated': '0.3', 'Naive CD8 T-cell activated': '0.6', 'Naive T-reg': '0.1'} | 1O6S, 2O72, 2OMT, 2OMU, 2OMV, 2OMX, 2OMY, 2OMZ, 3FF7, 3FF8, 3L6X, 3L6Y, 4ZT1, 4ZTE, 6CXY, 6OLE, 6OLF, 6OLG, 6VEL, 7STZ, 8H62 | {'Adipose Tissue': 1.2125261088039867, 'Adrenal Gland': 0.1914223992248062, 'Bladder': 39.2033519047619, 'Blood': 1.340954264800861, 'Blood Vessel': 0.3121561692883895, 'Brain': 0.8550442199091597, 'Breast': 38.54918344226579, 'Cervix Uteri': 23.539115789473684, 'Colon': 43.41292142490372, 'Esophagus': 53.97513367404844, 'Fallopian Tube': 14.900277777777776, 'Heart': 0.119140469221835, 'Kidney': 25.040449438202245, 'Liver': 26.60802654867257, 'Lung': 35.447986366782004, 'Muscle': 0.1378936151930261, 'Nerve': 17.518468982229404, 'Ovary': 3.6515122222222223, 'Pancreas': 56.89676829268293, 'Pituitary': 24.68741660777385, 'Prostate': 61.279967346938776, 'Salivary Gland': 92.01685185185184, 'Skin': 79.77571720232172, 'Small Intestine': 71.7519320855615, 'Spleen': 10.061029045643156, 'Stomach': 58.07813805013927, 'Testis': 0.8144204986149585, 'Thyroid': 135.176797856049, 'Uterus': 1.442593943661972, 'Vagina': 86.52345512820513} | CDCA5 | MSGRRTRSGGAAQRSGPRAPSPTKPLRRSQRKSGSELPSILPEIWPKTPSAAAVRKPIVLKRIVAHAVEVPAVQSPRRSPRISFFLEKENEPPGRELTKEDLFKTHSVPATPTSTPVPNPEAESSSKEGELDARDLEMSKKVRRSYSRLETLGSASTSTPGRRSCFGFEGLLGAEDLSGVSPVVCSKLTEVPRVCAKPWAPDMTLPGISPPPEKQKRKKKKMPEILKTELDEWAAAMNAEFEAAEQFDLLVE | Homo sapiens | Nucleus, Chromosome, Cytoplasm | Group enriched (bone marrow, lymphoid tissue, testis) | {'Ciliated cells': '0.7', 'Basal respiratory cells': '1.3', 'Club cells': '0.9', 'Ionocytes': '0.4', 'Mucus glandular cells': '0.9', 'Serous glandular cells': '2.5', 'Gastric mucus-secreting cells': '1.2', 'Proximal enterocytes': '0.6', 'Paneth cells': '1.2', 'Distal enterocytes': '0.5', 'Intestinal goblet cells': '4.3', 'Exocrine glandular cells': '-0.397', 'Basal prostatic cells': '0.1', 'Prostatic glandular cells': '0.4', 'Breast glandular cells': '0.326', 'Breast myoepithelial cells': '0.296', 'Glandular and luminal cells': '1.5', 'Secretory cells': '0.5', 'Basal keratinocytes': '5.1', 'Suprabasal keratinocytes': '1.6', 'Basal squamous epithelial cells': '2.9', 'Squamous epithelial cells': '6.0', 'Alveolar cells type 1': '-0.268', 'Alveolar cells type 2': '0.184', 'Salivary duct cells': '1.1', 'Ductal cells': '0.530', 'Hepatocytes': '0.341', 'Cholangiocytes': '0.0', 'Proximal tubular cells': '0.178', 'Distal tubular cells': '0.0', 'Collecting duct cells': '0.0', 'Mesothelial cells': '-0.080', 'Sertoli cells': '-0.438', 'Granulosa cells': '1.7', 'Enteroendocrine cells': '1.0', 'Pancreatic endocrine cells': '3.4', 'Leydig cells': '-0.481', 'Excitatory neurons': '1.0', 'Inhibitory neurons': '0.6', 'Cone photoreceptor cells': '1.7', 'Rod photoreceptor cells': '0.1', 'Bipolar cells': '0.3', 'Horizontal cells': '3.1', 'Astrocytes': '0.0', 'Oligodendrocyte precursor cells': '0.0', 'Oligodendrocytes': '0.6', 'Microglial cells': '0.9', 'Muller glia cells': '0.3', 'Schwann cells': '0.117', 'Spermatogonia': '-0.116', 'Spermatocytes': '0.265', 'Early spermatids': '0.713', 'Late spermatids': '0.466', 'Oocytes': '10.3', 'Cytotrophoblasts': '21.3', 'Syncytiotrophoblasts': '5.9', 'Extravillous trophoblasts': '38.9', 'Endothelial cells': '1.7', 'Lymphatic endothelial cells': '0.3', 'Cardiomyocytes': '0.486', 'Skeletal myocytes': '-0.098', 'Smooth muscle cells': '1.0', 'Adipocytes': '1.1', 'Melanocytes': '0.509', 'Fibroblasts': '2.5', 'Peritubular cells': '-0.346', 'Endometrial stromal cells': '1.3', 'Ovarian stromal cells': '0.4', 'Undifferentiated cells': '22.5', 'T-cells': '2.8', 'B-cells': '1.8', 'Plasma cells': '21.1', 'Nk-cells': '2.4', 'Granulocytes': '0.5', 'Monocytes': '0.2', 'Macrophages': '2.4', 'Hofbauer cells': '8.4', 'Kupffer cells': '2.8', 'Dendritic cells': '0.4', 'Langerhans cells': '0.213', 'Erythroid cells': '0.056', 'Adipocytes (Subcutaneous)': '-0.100', 'Adipocytes (Visceral)': '0.035', 'Breast glandular cells (progenitors)': '0.294', 'Adipocytes (Breast)': '-0.282', 'Colon enterocytes': '0.306', 'Colon enteroendocrine cells': '-0.118', 'Enteric glia cells': '-0.330', 'Mitotic cells (Colon)': '0.659', 'Mitotic cells (Heart)': '0.763', 'Podocytes': '-0.264', 'Ascending Loop of Henle cells': '0.383', 'Intercalated cells': '-0.134', 'Cholangiocyte': '0.314', 'NK-cells (Liver)': '-0.197', 'Respiratory ciliated cells': '0.006', 'Mitotic cells (Lung)': '0.876', 'NK-cells (Lung)': '-0.173', 'B-cells (Lung)': '-0.029', 'Alpha cells': '0.235', 'Beta cells': '0.115', 'Prostate glandular cells': '-0.030', 'Prostate basal glandular cells': '0.267', 'Urothelial cells': '0.218', 'Keratinocyte (other)': '0.275', 'Keratinocyte (granular)': '-0.200', 'Hair cortex cells': '0.098', 'Inner root sheath cells': '0.214', 'Outer root sheath cells': '0.228', 'Sebaceous gland cells': '0.121', 'Eccrine sweat gland cells': '-0.077', 'Adipocytes (Skin)': '-0.195', 'Mitotic cells (Skin)': '0.840', 'Parietal cells': '-0.099', 'Chief cells': '-0.066', 'Gastric mucous cells': '0.379', 'Gastric enteroendocrine cells': '0.051', 'Mitotic cells (Stomach)': '0.911', 'Parafollicular cells': '-0.047', 'Thyroid glandular cells': '-0.023', 'Mitotic cells (Thyroid)': '0.598', 'Adrenal cortex cells': '0.393', 'Adrenal medulla cells': '0.112', 'Mitotic cells (Adrenal gland)': '0.915', 'Minor salivary glandular cells': '0.226', 'Minor salivary gland ductal cells': '-0.298', 'Minor salivary gland basal cells': '0.659', 'Mitotic cells (Minor salivary gland)': '0.928', 'Adipocytes (Minor salivary gland)': '0.186', 'Somatotropes': '-0.041', 'Lactotropes': '-0.226', 'Gonadotropes': '-0.050', 'Corticotropes': '-0.218', 'Thyrotropes': '-0.122', 'Undifferentiated cells (Pituitary gland)': '0.389', 'Mitotic cells (Spleen)': '0.911', 'Platelets': '0.190', 'Erythrocytes': '0.316', 'Hematopoietic stem cells': '0.372', 'B-cells (Spleen)': '-0.121', 'NK-cells (Spleen)': '-0.269', 'Amygdala excitatory': '0.5', 'Cerebellar inhibitory': '0.9', 'Cge interneuron': '0.4', 'Deep-layer corticothalamic and 6b': '0.9', 'Deep-layer intratelencephalic': '1.0', 'Deep-layer near-projecting': '0.8', 'Eccentric medium spiny neuron': '0.4', 'Hippocampal ca1-3': '1.0', 'Hippocampal ca4': '0.6', 'Hippocampal dentate gyrus': '0.5', 'Lamp5-lhx6 and chandelier': '0.4', 'Lower rhombic lip': '1.6', 'Mammillary body': '0.7', 'Medium spiny neuron': '0.4', 'Mge interneuron': '0.6', 'Midbrain-derived inhibitory': '0.7', 'Miscellaneous': '1.2', 'Splatter': '0.6', 'Thalamic excitatory': '0.9', 'Upper rhombic lip': '1.3', 'Upper-layer intratelencephalic': '1.0', 'Astrocyte': '0.3', 'Bergmann glia': '0.2', 'Central nervous system macrophage': '0.3', 'Choroid plexus epithelial cell': '0.3', 'Committed oligodendrocyte precursor': '0.6', 'Ependymal cell': '0.2', 'Oligodendrocyte': '0.5', 'Oligodendrocyte precursor cell': '0.3', 'Endothelial cell': '0.3', 'Pericyte': '0.0', 'Vascular associated smooth muscle cell': '0.2', 'Fibroblast': '0.5', 'Leukocyte': '0.1', 'Basophil': '0.8', 'Eosinophil': '0.2', 'Neutrophil': '0.8', 'Classical monocyte': '0.2', 'Non-classical monocyte': '0.5', 'Intermediate monocyte': '0.3', 'T-reg': '4.9', 'GdT-cell': '0.4', 'MAIT T-cell': '0.3', 'Memory CD4 T-cell': '0.5', 'Naive CD4 T-cell': '0.4', 'Memory CD8 T-cell': '0.3', 'Naive CD8 T-cell': '0.3', 'Memory B-cell': '0.3', 'Naive B-cell': '0.5', 'Plasmacytoid DC': '1.6', 'Myeloid DC': '0.9', 'NK-cell': '2.2', 'Total PBMC': '2.4', 'Vd2 gdTCR': '0.2', 'Memory CD4 T-cell Th1\\/Th17': '0.3', 'Memory CD4 T-cell Th17': '0.6', 'Memory CD4 T-cell Th2': '0.7', 'Non-Vd2 gdTCR': '1.0', 'Memory CD4 T-cell Th1': '1.3', 'Memory CD4 T-cell TFH': '0.4', 'Terminal effector memory CD4 T-cell': '0.0', 'Central memory CD8 T-cell': '0.5', 'Effector memory CD8 T-cell': '3.2', 'Terminal effector memory CD8 T-cell': '0.9', 'Non-switched memory B-cell': '0.6', 'Plasmablast': '37.6', 'Switched memory B-cell': '1.3', 'Exhausted memory B-cell': '9.5', 'Progenitor cell': '3.1', 'Memory T-reg': '4.7', 'Naive CD4 T-cell activated': '0.7', 'Naive CD8 T-cell activated': '0.7', 'Naive T-reg': '0.6'} | null | {'Adipose Tissue': 1.315615365448505, 'Adrenal Gland': 1.4035717054263566, 'Bladder': 1.4172333333333331, 'Blood': 14.750220139935411, 'Blood Vessel': 0.8903569288389513, 'Brain': 1.2125449394398182, 'Breast': 1.2887961220043571, 'Cervix Uteri': 1.886715789473684, 'Colon': 2.7703213093709884, 'Esophagus': 4.611380256055363, 'Fallopian Tube': 1.1682777777777775, 'Heart': 0.5252589547038328, 'Kidney': 0.937823595505618, 'Liver': 0.8826044247787611, 'Lung': 3.2854162629757786, 'Muscle': 0.4393217310087173, 'Nerve': 0.9960046849757672, 'Ovary': 1.2204616666666666, 'Pancreas': 0.3526619512195121, 'Pituitary': 0.8254855123674912, 'Prostate': 1.3771114285714283, 'Salivary Gland': 1.9042814814814817, 'Skin': 10.058297346600332, 'Small Intestine': 5.629671122994652, 'Spleen': 8.386151452282158, 'Stomach': 2.461782506963788, 'Testis': 53.67396121883656, 'Thyroid': 1.1105546248085758, 'Uterus': 1.2081598591549294, 'Vagina': 4.175232692307692} | [39.93, 46.46, 52.9, 44.21, 41.4, 39.93, 35.91, 38.61, 36.44, 36.25, 34.86, 32.82, 32.01, 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Forms a ternary complex composed of ADAM10, CADH1 and EPHA4, | null | null | KLRG1, SPEF1, DLGAP5, AJAP1, RAPGEF2, RAB8B, PIP5K1C, PKP2, TRPV4, CTNNB1, CAV1, DDR1, TBC1D2, CTNNA1, JUP, CTNND1, PSEN1, LIMA1, CDH1, JUP, ADAM10, CADH1 , EPHA4, | null | null | null | null | Homodimer | null | 79.91949 | 0.474025 | 63.132063 | 0.816071 | 2,553 |
P12830 | Q96GD4 | null | degron_data | CDH1 | MGPWSRSLSALLLLLQVSSWLCQEPEPCHPGFDAESYTFTVPRRHLERGRVLGRVNFEDCTGRQRTAYFSLDTRFKVGTDGVITVKRPLRFHNPQIHFLVYAWDSTYRKFSTKVTLNTVGHHHRPPPHQASVSGIQAELLTFPNSSPGLRRQKRDWVIPPISCPENEKGPFPKNLVQIKSNKDKEGKVFYSITGQGADTPPVGVFIIERETGWLKVTEPLDRERIATYTLFSHAVSSNGNAVEDPMEILITVTDQNDNKPEFTQEVFKGSVMEGALPGTSVMEVTATDADDDVNTYNAAIAYTILSQDPELPDKNMFTINRNTGVISVVTTGLDRESFPTYTLVVQAADLQGEGLSTTATAVITVTDTNDNPPIFNPTTYKGQVPENEANVVITTLKVTDADAPNTPAWEAVYTILNDDGGQFVVTTNPVNNDGILKTAKGLDFEAKQQYILHVAVTNVVPFEVSLTTSTATVTVDVLDVNEAPIFVPPEKRVEVSEDFGVGQEITSYTAQEPDTFMEQKITYRIWRDTANWLEINPDTGAISTRAELDREDFEHVKNSTYTALIIATDNGSPVATGTGTLLLILSDVNDNAPIPEPRTIFFCERNPKPQVINIIDADLPPNTSPFTAELTHGASANWTIQYNDPTQESIILKPKMALEVGDYKINLKLMDNQNKDQVTTLEVSVCDCEGAAGVCRKAQPVEAGLQIPAILGILGGILALLILILLLLLFLRRRAVVKEPLLPPEDDTRDNVYYYDEEGGGEEDQDFDLSQLHRGLDARPEVTRNDVAPTLMSVPRYLPRPANPDEIGNFIDENLKAADTDPTAPPYDSLLVFDYEGSGSEAASLSSLNSSESDKDQDYDYLNEWGNRFKKLADMYGGGEDD | Homo sapiens | Cell junction, adherens junction, Cell membrane, Endosome, Golgi apparatus, trans-Golgi network, Cytoplasm, Cell junction, desmosome | Tissue enhanced (parathyroid) | {'Ciliated cells': '119.1', 'Basal respiratory cells': '71.1', 'Club cells': '97.3', 'Ionocytes': '81.0', 'Mucus glandular cells': '155.0', 'Serous glandular cells': '67.8', 'Gastric mucus-secreting cells': '133.2', 'Proximal enterocytes': '140.9', 'Paneth cells': '125.1', 'Distal enterocytes': '307.5', 'Intestinal goblet cells': '173.5', 'Exocrine glandular cells': '-0.605', 'Basal prostatic cells': '68.3', 'Prostatic glandular cells': '186.7', 'Breast glandular cells': '0.773', 'Breast myoepithelial cells': '0.700', 'Glandular and luminal cells': '313.0', 'Secretory cells': '82.3', 'Basal keratinocytes': '102.5', 'Suprabasal keratinocytes': '162.6', 'Basal squamous epithelial cells': '51.0', 'Squamous epithelial cells': '106.9', 'Alveolar cells type 1': '0.437', 'Alveolar cells type 2': '0.706', 'Salivary duct cells': '95.9', 'Ductal cells': '0.541', 'Hepatocytes': '0.600', 'Cholangiocytes': '129.7', 'Proximal tubular cells': '0.042', 'Distal tubular cells': '0.0', 'Collecting duct cells': '143.9', 'Mesothelial cells': '0.799', 'Sertoli cells': '0.252', 'Granulosa cells': '12.9', 'Enteroendocrine cells': '92.4', 'Pancreatic endocrine cells': '78.1', 'Leydig cells': '0.264', 'Excitatory neurons': '0.7', 'Inhibitory neurons': '1.3', 'Cone photoreceptor cells': '0.0', 'Rod photoreceptor cells': '0.0', 'Bipolar cells': '0.2', 'Horizontal cells': '0.6', 'Astrocytes': '0.6', 'Oligodendrocyte precursor cells': '0.5', 'Oligodendrocytes': '29.9', 'Microglial cells': '0.9', 'Muller glia cells': '0.1', 'Schwann cells': '0.131', 'Spermatogonia': '0.392', 'Spermatocytes': '0.193', 'Early spermatids': '-0.217', 'Late spermatids': '-0.290', 'Oocytes': '16.9', 'Cytotrophoblasts': '119.2', 'Syncytiotrophoblasts': '45.0', 'Extravillous trophoblasts': '24.9', 'Endothelial cells': '6.1', 'Lymphatic endothelial cells': '0.4', 'Cardiomyocytes': '0.135', 'Skeletal myocytes': '0.107', 'Smooth muscle cells': '5.8', 'Adipocytes': '2.1', 'Melanocytes': '0.335', 'Fibroblasts': '6.5', 'Peritubular cells': '0.210', 'Endometrial stromal cells': '27.7', 'Ovarian stromal cells': '0.7', 'Undifferentiated cells': '101.6', 'T-cells': '2.9', 'B-cells': '4.4', 'Plasma cells': '6.1', 'Nk-cells': '0.0', 'Granulocytes': '8.4', 'Monocytes': '0.0', 'Macrophages': '6.0', 'Hofbauer cells': '4.3', 'Kupffer cells': '1.0', 'Dendritic cells': '5.9', 'Langerhans cells': '0.304', 'Erythroid cells': '0.036', 'Adipocytes (Subcutaneous)': '-0.081', 'Adipocytes (Visceral)': '-0.209', 'Breast glandular cells (progenitors)': '0.538', 'Adipocytes (Breast)': '-0.689', 'Colon enterocytes': '0.790', 'Colon enteroendocrine cells': '0.112', 'Enteric glia cells': '-0.048', 'Mitotic cells (Colon)': '0.299', 'Mitotic cells (Heart)': '0.120', 'Podocytes': '-0.118', 'Ascending Loop of Henle cells': '0.475', 'Intercalated cells': '0.212', 'Cholangiocyte': '0.090', 'NK-cells (Liver)': '-0.005', 'Respiratory ciliated cells': '-0.012', 'Mitotic cells (Lung)': '0.071', 'NK-cells (Lung)': '-0.266', 'B-cells (Lung)': '-0.296', 'Alpha cells': '0.270', 'Beta cells': '0.152', 'Prostate glandular cells': '0.764', 'Prostate basal glandular cells': '0.540', 'Urothelial cells': '0.205', 'Keratinocyte (other)': '0.510', 'Keratinocyte (granular)': '0.055', 'Hair cortex cells': '0.080', 'Inner root sheath cells': '0.131', 'Outer root sheath cells': '0.175', 'Sebaceous gland cells': '0.156', 'Eccrine sweat gland cells': '-0.207', 'Adipocytes (Skin)': '-0.244', 'Mitotic cells (Skin)': '0.442', 'Parietal cells': '0.654', 'Chief cells': '0.649', 'Gastric mucous cells': '0.781', 'Gastric enteroendocrine cells': '0.590', 'Mitotic cells (Stomach)': '0.445', 'Parafollicular cells': '0.173', 'Thyroid glandular cells': '0.865', 'Mitotic cells (Thyroid)': '-0.081', 'Adrenal cortex cells': '0.051', 'Adrenal medulla cells': '0.087', 'Mitotic cells (Adrenal gland)': '0.072', 'Minor salivary glandular cells': '0.371', 'Minor salivary gland ductal cells': '-0.142', 'Minor salivary gland basal cells': '0.582', 'Mitotic cells (Minor salivary gland)': '0.567', 'Adipocytes (Minor salivary gland)': '0.050', 'Somatotropes': '0.121', 'Lactotropes': '0.322', 'Gonadotropes': '0.330', 'Corticotropes': '0.180', 'Thyrotropes': '0.496', 'Undifferentiated cells (Pituitary gland)': '-0.108', 'Mitotic cells (Spleen)': '-0.228', 'Platelets': '-0.050', 'Erythrocytes': '-0.158', 'Hematopoietic stem cells': '-0.211', 'B-cells (Spleen)': '0.266', 'NK-cells (Spleen)': '0.309', 'Amygdala excitatory': '1.0', 'Cerebellar inhibitory': '0.9', 'Cge interneuron': '0.7', 'Deep-layer corticothalamic and 6b': '1.5', 'Deep-layer intratelencephalic': '0.7', 'Deep-layer near-projecting': '0.7', 'Eccentric medium spiny neuron': '0.6', 'Hippocampal ca1-3': '1.9', 'Hippocampal ca4': '1.2', 'Hippocampal dentate gyrus': '1.1', 'Lamp5-lhx6 and chandelier': '0.5', 'Lower rhombic lip': '0.8', 'Mammillary body': '0.6', 'Medium spiny neuron': '0.7', 'Mge interneuron': '1.7', 'Midbrain-derived inhibitory': '0.7', 'Miscellaneous': '0.9', 'Splatter': '3.8', 'Thalamic excitatory': '0.5', 'Upper rhombic lip': '0.8', 'Upper-layer intratelencephalic': '0.6', 'Astrocyte': '4.4', 'Bergmann glia': '0.2', 'Central nervous system macrophage': '0.6', 'Choroid plexus epithelial cell': '52.1', 'Committed oligodendrocyte precursor': '41.5', 'Ependymal cell': '4.8', 'Oligodendrocyte': '53.1', 'Oligodendrocyte precursor cell': '2.4', 'Endothelial cell': '0.7', 'Pericyte': '0.3', 'Vascular associated smooth muscle cell': '0.0', 'Fibroblast': '17.4', 'Leukocyte': '1.1', 'Basophil': '0.0', 'Eosinophil': '0.0', 'Neutrophil': '0.0', 'Classical monocyte': '0.0', 'Non-classical monocyte': '0.0', 'Intermediate monocyte': '0.0', 'T-reg': '2.3', 'GdT-cell': '0.0', 'MAIT T-cell': '0.0', 'Memory CD4 T-cell': '0.0', 'Naive CD4 T-cell': '0.1', 'Memory CD8 T-cell': '0.2', 'Naive CD8 T-cell': '0.3', 'Memory B-cell': '0.0', 'Naive B-cell': '0.1', 'Plasmacytoid DC': '46.6', 'Myeloid DC': '8.5', 'NK-cell': '0.1', 'Total PBMC': '0.7', 'Vd2 gdTCR': '0.0', 'Memory CD4 T-cell Th1\\/Th17': '0.1', 'Memory CD4 T-cell Th17': '0.2', 'Memory CD4 T-cell Th2': '2.9', 'Non-Vd2 gdTCR': '0.1', 'Memory CD4 T-cell Th1': '0.3', 'Memory CD4 T-cell TFH': '0.5', 'Terminal effector memory CD4 T-cell': '0.0', 'Central memory CD8 T-cell': '4.8', 'Effector memory CD8 T-cell': '0.0', 'Terminal effector memory CD8 T-cell': '0.6', 'Non-switched memory B-cell': '0.0', 'Plasmablast': '3.3', 'Switched memory B-cell': '0.0', 'Exhausted memory B-cell': '0.7', 'Progenitor cell': '2.3', 'Memory T-reg': '1.3', 'Naive CD4 T-cell activated': '0.3', 'Naive CD8 T-cell activated': '0.6', 'Naive T-reg': '0.1'} | 1O6S, 2O72, 2OMT, 2OMU, 2OMV, 2OMX, 2OMY, 2OMZ, 3FF7, 3FF8, 3L6X, 3L6Y, 4ZT1, 4ZTE, 6CXY, 6OLE, 6OLF, 6OLG, 6VEL, 7STZ, 8H62 | {'Adipose Tissue': 1.2125261088039867, 'Adrenal Gland': 0.1914223992248062, 'Bladder': 39.2033519047619, 'Blood': 1.340954264800861, 'Blood Vessel': 0.3121561692883895, 'Brain': 0.8550442199091597, 'Breast': 38.54918344226579, 'Cervix Uteri': 23.539115789473684, 'Colon': 43.41292142490372, 'Esophagus': 53.97513367404844, 'Fallopian Tube': 14.900277777777776, 'Heart': 0.119140469221835, 'Kidney': 25.040449438202245, 'Liver': 26.60802654867257, 'Lung': 35.447986366782004, 'Muscle': 0.1378936151930261, 'Nerve': 17.518468982229404, 'Ovary': 3.6515122222222223, 'Pancreas': 56.89676829268293, 'Pituitary': 24.68741660777385, 'Prostate': 61.279967346938776, 'Salivary Gland': 92.01685185185184, 'Skin': 79.77571720232172, 'Small Intestine': 71.7519320855615, 'Spleen': 10.061029045643156, 'Stomach': 58.07813805013927, 'Testis': 0.8144204986149585, 'Thyroid': 135.176797856049, 'Uterus': 1.442593943661972, 'Vagina': 86.52345512820513} | AURKB | MAQKENSYPWPYGRQTAPSGLSTLPQRVLRKEPVTPSALVLMSRSNVQPTAAPGQKVMENSSGTPDILTRHFTIDDFEIGRPLGKGKFGNVYLAREKKSHFIVALKVLFKSQIEKEGVEHQLRREIEIQAHLHHPNILRLYNYFYDRRRIYLILEYAPRGELYKELQKSCTFDEQRTATIMEELADALMYCHGKKVIHRDIKPENLLLGLKGELKIADFGWSVHAPSLRRKTMCGTLDYLPPEMIEGRMHNEKVDLWCIGVLCYELLVGNPPFESASHNETYRRIVKVDLKFPASVPMGAQDLISKLLRHNPSERLPLAQVSAHPWVRANSRRVLPPSALQSVA | Homo sapiens | Nucleus, Chromosome, Chromosome, centromere, Chromosome, centromere, kinetochore, Cytoplasm, cytoskeleton, spindle, Midbody | Tissue enhanced (bone marrow, lymphoid tissue) | {'Ciliated cells': '0.3', 'Basal respiratory cells': '6.1', 'Club cells': '0.9', 'Ionocytes': '1.1', 'Mucus glandular cells': '0.4', 'Serous glandular cells': '4.7', 'Gastric mucus-secreting cells': '6.5', 'Proximal enterocytes': '1.5', 'Paneth cells': '0.3', 'Distal enterocytes': '1.5', 'Intestinal goblet cells': '11.0', 'Exocrine glandular cells': '-0.317', 'Basal prostatic cells': '0.0', 'Prostatic glandular cells': '0.0', 'Breast glandular cells': '0.203', 'Breast myoepithelial cells': '0.234', 'Glandular and luminal cells': '2.0', 'Secretory cells': '0.3', 'Basal keratinocytes': '8.6', 'Suprabasal keratinocytes': '4.8', 'Basal squamous epithelial cells': '1.6', 'Squamous epithelial cells': '11.1', 'Alveolar cells type 1': '-0.225', 'Alveolar cells type 2': '0.255', 'Salivary duct cells': '0.8', 'Ductal cells': '0.446', 'Hepatocytes': '0.198', 'Cholangiocytes': '0.0', 'Proximal tubular cells': '0.094', 'Distal tubular cells': '0.0', 'Collecting duct cells': '0.0', 'Mesothelial cells': '-0.041', 'Sertoli cells': '0.001', 'Granulosa cells': '2.3', 'Enteroendocrine cells': '1.6', 'Pancreatic endocrine cells': '11.9', 'Leydig cells': '0.026', 'Excitatory neurons': '0.0', 'Inhibitory neurons': '0.0', 'Cone photoreceptor cells': '0.0', 'Rod photoreceptor cells': '0.2', 'Bipolar cells': '0.0', 'Horizontal cells': '0.0', 'Astrocytes': '0.0', 'Oligodendrocyte precursor cells': '0.0', 'Oligodendrocytes': '0.1', 'Microglial cells': '0.0', 'Muller glia cells': '0.0', 'Schwann cells': '0.117', 'Spermatogonia': '0.163', 'Spermatocytes': '0.333', 'Early spermatids': '0.234', 'Late spermatids': '0.007', 'Oocytes': '8.1', 'Cytotrophoblasts': '43.9', 'Syncytiotrophoblasts': '11.6', 'Extravillous trophoblasts': '91.8', 'Endothelial cells': '2.1', 'Lymphatic endothelial cells': '0.2', 'Cardiomyocytes': '0.235', 'Skeletal myocytes': '0.002', 'Smooth muscle cells': '2.2', 'Adipocytes': '0.3', 'Melanocytes': '0.474', 'Fibroblasts': '4.6', 'Peritubular cells': '-0.106', 'Endometrial stromal cells': '1.0', 'Ovarian stromal cells': '0.1', 'Undifferentiated cells': '41.4', 'T-cells': '4.1', 'B-cells': '2.8', 'Plasma cells': '25.9', 'Nk-cells': '2.6', 'Granulocytes': '0.3', 'Monocytes': '0.2', 'Macrophages': '4.8', 'Hofbauer cells': '24.0', 'Kupffer cells': '4.2', 'Dendritic cells': '0.0', 'Langerhans cells': '0.202', 'Erythroid cells': '0.097', 'Adipocytes (Subcutaneous)': '-0.200', 'Adipocytes (Visceral)': '-0.086', 'Breast glandular cells (progenitors)': '0.203', 'Adipocytes (Breast)': '-0.163', 'Colon enterocytes': '0.353', 'Colon enteroendocrine cells': '-0.138', 'Enteric glia cells': '-0.227', 'Mitotic cells (Colon)': '0.731', 'Mitotic cells (Heart)': '0.800', 'Podocytes': '-0.268', 'Ascending Loop of Henle cells': '0.250', 'Intercalated cells': '-0.208', 'Cholangiocyte': '0.204', 'NK-cells (Liver)': '-0.010', 'Respiratory ciliated cells': '-0.029', 'Mitotic cells (Lung)': '0.839', 'NK-cells (Lung)': '-0.099', 'B-cells (Lung)': '0.023', 'Alpha cells': '0.174', 'Beta cells': '0.038', 'Prostate glandular cells': '-0.097', 'Prostate basal glandular cells': '0.206', 'Urothelial cells': '0.307', 'Keratinocyte (other)': '0.306', 'Keratinocyte (granular)': '-0.208', 'Hair cortex cells': '0.058', 'Inner root sheath cells': '0.171', 'Outer root sheath cells': '0.210', 'Sebaceous gland cells': '0.035', 'Eccrine sweat gland cells': '-0.083', 'Adipocytes (Skin)': '-0.192', 'Mitotic cells (Skin)': '0.846', 'Parietal cells': '0.183', 'Chief cells': '0.170', 'Gastric mucous cells': '0.613', 'Gastric enteroendocrine cells': '0.255', 'Mitotic cells (Stomach)': '0.926', 'Parafollicular cells': '-0.103', 'Thyroid glandular cells': '-0.168', 'Mitotic cells (Thyroid)': '0.747', 'Adrenal cortex cells': '0.395', 'Adrenal medulla cells': '0.123', 'Mitotic cells (Adrenal gland)': '0.918', 'Minor salivary glandular cells': '0.097', 'Minor salivary gland ductal cells': '-0.326', 'Minor salivary gland basal cells': '0.652', 'Mitotic cells (Minor salivary gland)': '0.917', 'Adipocytes (Minor salivary gland)': '0.181', 'Somatotropes': '-0.294', 'Lactotropes': '-0.246', 'Gonadotropes': '-0.072', 'Corticotropes': '-0.147', 'Thyrotropes': '-0.116', 'Undifferentiated cells (Pituitary gland)': '0.348', 'Mitotic cells (Spleen)': '0.902', 'Platelets': '0.196', 'Erythrocytes': '0.277', 'Hematopoietic stem cells': '0.390', 'B-cells (Spleen)': '-0.085', 'NK-cells (Spleen)': '-0.256', 'Amygdala excitatory': '0.0', 'Cerebellar 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0.72, 0.88, 0.87, 0.88, 0.89, 0.89, 0.96, 0.95, 0.98, 0.95, 0.96, 1.0, 0.92, 0.98, 0.97, 0.91, 0.97, 0.83, 0.96, 0.89, 0.85, 0.81, 0.87, 0.83, 0.47, 0.34, 0.82, 0.05, 0.46, 0.36, 0.7, 0.22, 0.05, 0.4, 0.48, 0.59, 0.66, 0.72, 0.29, 0.34, 0.9, 0.54, 0.8, 0.24, 0.16, 0.29, 0.22, 0.29, 0.22, 0.04, 0.41, 0.02, 0.44, 0.75, 0.36, 0.57, 0.23, 0.48, 0.0, 0.06, 0.0, 0.21, 0.11, 0.04, 0.35, 0.24, 0.63, 0.43, 0.04, 0.69, 0.89, 0.53, 0.67, 0.17, 0.5, 0.72, 0.41, 0.11, 0.59, 0.51, 0.1, 0.12, 0.63, 0.1, 0.03, 0.29, 0.54, 0.03, 0.51, 0.18, 0.24, 0.03, 0.02, 0.06, 0.12, 0.03, 0.11, 0.07, 0.43, 0.07, 0.74, 0.37, 0.95, 0.79, 0.4, 0.19, 0.03, 0.01, 0.0, 0.07, 0.2, 0.26, 0.12, 0.37, 0.44, 0.27, 0.27, 0.0, 0.32, 0.55, 0.26, 0.04, 0.58, 0.8, 0.48, 0.62, 0.47, 0.1, 0.63, 0.34, 0.48, 0.23, 0.0, 0.0, 0.09, 0.0, 0.02, 0.24, 0.03, 0.01, 0.0, 0.3, 0.0, 0.0, 0.4, 0.26, 0.01, 0.16, 0.67, 0.39, 0.49, 0.05, 0.09, 0.01, 0.07, 0.08, 0.01, 0.14, 0.0, 0.45, 0.11, 0.0, 0.2, 0.0, 0.04, 0.75, 0.75, 0.02, 0.18, 0.0, 0.07, 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Forms a ternary complex composed of ADAM10, CADH1 and EPHA4, | null | null | KLRG1, SPEF1, DLGAP5, AJAP1, RAPGEF2, RAB8B, PIP5K1C, PKP2, TRPV4, CTNNB1, CAV1, DDR1, TBC1D2, CTNNA1, JUP, CTNND1, PSEN1, LIMA1, CDH1, JUP, ADAM10, CADH1 , EPHA4, | null | null | null | null | Homodimer | null | 79.91949 | 0.474025 | 78.962151 | 0.410058 | 1,950 |
P12830 | Q96GD4-2 | null | degron_data | CDH1 | MGPWSRSLSALLLLLQVSSWLCQEPEPCHPGFDAESYTFTVPRRHLERGRVLGRVNFEDCTGRQRTAYFSLDTRFKVGTDGVITVKRPLRFHNPQIHFLVYAWDSTYRKFSTKVTLNTVGHHHRPPPHQASVSGIQAELLTFPNSSPGLRRQKRDWVIPPISCPENEKGPFPKNLVQIKSNKDKEGKVFYSITGQGADTPPVGVFIIERETGWLKVTEPLDRERIATYTLFSHAVSSNGNAVEDPMEILITVTDQNDNKPEFTQEVFKGSVMEGALPGTSVMEVTATDADDDVNTYNAAIAYTILSQDPELPDKNMFTINRNTGVISVVTTGLDRESFPTYTLVVQAADLQGEGLSTTATAVITVTDTNDNPPIFNPTTYKGQVPENEANVVITTLKVTDADAPNTPAWEAVYTILNDDGGQFVVTTNPVNNDGILKTAKGLDFEAKQQYILHVAVTNVVPFEVSLTTSTATVTVDVLDVNEAPIFVPPEKRVEVSEDFGVGQEITSYTAQEPDTFMEQKITYRIWRDTANWLEINPDTGAISTRAELDREDFEHVKNSTYTALIIATDNGSPVATGTGTLLLILSDVNDNAPIPEPRTIFFCERNPKPQVINIIDADLPPNTSPFTAELTHGASANWTIQYNDPTQESIILKPKMALEVGDYKINLKLMDNQNKDQVTTLEVSVCDCEGAAGVCRKAQPVEAGLQIPAILGILGGILALLILILLLLLFLRRRAVVKEPLLPPEDDTRDNVYYYDEEGGGEEDQDFDLSQLHRGLDARPEVTRNDVAPTLMSVPRYLPRPANPDEIGNFIDENLKAADTDPTAPPYDSLLVFDYEGSGSEAASLSSLNSSESDKDQDYDYLNEWGNRFKKLADMYGGGEDD | Homo sapiens | Cell junction, adherens junction, Cell membrane, Endosome, Golgi apparatus, trans-Golgi network, Cytoplasm, Cell junction, desmosome | Tissue enhanced (parathyroid) | {'Ciliated cells': '119.1', 'Basal respiratory cells': '71.1', 'Club cells': '97.3', 'Ionocytes': '81.0', 'Mucus glandular cells': '155.0', 'Serous glandular cells': '67.8', 'Gastric mucus-secreting cells': '133.2', 'Proximal enterocytes': '140.9', 'Paneth cells': '125.1', 'Distal enterocytes': '307.5', 'Intestinal goblet cells': '173.5', 'Exocrine glandular cells': '-0.605', 'Basal prostatic cells': '68.3', 'Prostatic glandular cells': '186.7', 'Breast glandular cells': '0.773', 'Breast myoepithelial cells': '0.700', 'Glandular and luminal cells': '313.0', 'Secretory cells': '82.3', 'Basal keratinocytes': '102.5', 'Suprabasal keratinocytes': '162.6', 'Basal squamous epithelial cells': '51.0', 'Squamous epithelial cells': '106.9', 'Alveolar cells type 1': '0.437', 'Alveolar cells type 2': '0.706', 'Salivary duct cells': '95.9', 'Ductal cells': '0.541', 'Hepatocytes': '0.600', 'Cholangiocytes': '129.7', 'Proximal tubular cells': '0.042', 'Distal tubular cells': '0.0', 'Collecting duct cells': '143.9', 'Mesothelial cells': '0.799', 'Sertoli cells': '0.252', 'Granulosa cells': '12.9', 'Enteroendocrine cells': '92.4', 'Pancreatic endocrine cells': '78.1', 'Leydig cells': '0.264', 'Excitatory neurons': '0.7', 'Inhibitory neurons': '1.3', 'Cone photoreceptor cells': '0.0', 'Rod photoreceptor cells': '0.0', 'Bipolar cells': '0.2', 'Horizontal cells': '0.6', 'Astrocytes': '0.6', 'Oligodendrocyte precursor cells': '0.5', 'Oligodendrocytes': '29.9', 'Microglial cells': '0.9', 'Muller glia cells': '0.1', 'Schwann cells': '0.131', 'Spermatogonia': '0.392', 'Spermatocytes': '0.193', 'Early spermatids': '-0.217', 'Late spermatids': '-0.290', 'Oocytes': '16.9', 'Cytotrophoblasts': '119.2', 'Syncytiotrophoblasts': '45.0', 'Extravillous trophoblasts': '24.9', 'Endothelial cells': '6.1', 'Lymphatic endothelial cells': '0.4', 'Cardiomyocytes': '0.135', 'Skeletal myocytes': '0.107', 'Smooth muscle cells': '5.8', 'Adipocytes': '2.1', 'Melanocytes': '0.335', 'Fibroblasts': '6.5', 'Peritubular cells': '0.210', 'Endometrial stromal cells': '27.7', 'Ovarian stromal cells': '0.7', 'Undifferentiated cells': '101.6', 'T-cells': '2.9', 'B-cells': '4.4', 'Plasma cells': '6.1', 'Nk-cells': '0.0', 'Granulocytes': '8.4', 'Monocytes': '0.0', 'Macrophages': '6.0', 'Hofbauer cells': '4.3', 'Kupffer cells': '1.0', 'Dendritic cells': '5.9', 'Langerhans cells': '0.304', 'Erythroid cells': '0.036', 'Adipocytes (Subcutaneous)': '-0.081', 'Adipocytes (Visceral)': '-0.209', 'Breast glandular cells (progenitors)': '0.538', 'Adipocytes (Breast)': '-0.689', 'Colon enterocytes': '0.790', 'Colon enteroendocrine cells': '0.112', 'Enteric glia cells': '-0.048', 'Mitotic cells (Colon)': '0.299', 'Mitotic cells (Heart)': '0.120', 'Podocytes': '-0.118', 'Ascending Loop of Henle cells': '0.475', 'Intercalated cells': '0.212', 'Cholangiocyte': '0.090', 'NK-cells (Liver)': '-0.005', 'Respiratory ciliated cells': '-0.012', 'Mitotic cells (Lung)': '0.071', 'NK-cells (Lung)': '-0.266', 'B-cells (Lung)': '-0.296', 'Alpha cells': '0.270', 'Beta cells': '0.152', 'Prostate glandular cells': '0.764', 'Prostate basal glandular cells': '0.540', 'Urothelial cells': '0.205', 'Keratinocyte (other)': '0.510', 'Keratinocyte (granular)': '0.055', 'Hair cortex cells': '0.080', 'Inner root sheath cells': '0.131', 'Outer root sheath cells': '0.175', 'Sebaceous gland cells': '0.156', 'Eccrine sweat gland cells': '-0.207', 'Adipocytes (Skin)': '-0.244', 'Mitotic cells (Skin)': '0.442', 'Parietal cells': '0.654', 'Chief cells': '0.649', 'Gastric mucous cells': '0.781', 'Gastric enteroendocrine cells': '0.590', 'Mitotic cells (Stomach)': '0.445', 'Parafollicular cells': '0.173', 'Thyroid glandular cells': '0.865', 'Mitotic cells (Thyroid)': '-0.081', 'Adrenal cortex cells': '0.051', 'Adrenal medulla cells': '0.087', 'Mitotic cells (Adrenal gland)': '0.072', 'Minor salivary glandular cells': '0.371', 'Minor salivary gland ductal cells': '-0.142', 'Minor salivary gland basal cells': '0.582', 'Mitotic cells (Minor salivary gland)': '0.567', 'Adipocytes (Minor salivary gland)': '0.050', 'Somatotropes': '0.121', 'Lactotropes': '0.322', 'Gonadotropes': '0.330', 'Corticotropes': '0.180', 'Thyrotropes': '0.496', 'Undifferentiated cells (Pituitary gland)': '-0.108', 'Mitotic cells (Spleen)': '-0.228', 'Platelets': '-0.050', 'Erythrocytes': '-0.158', 'Hematopoietic stem cells': '-0.211', 'B-cells (Spleen)': '0.266', 'NK-cells (Spleen)': '0.309', 'Amygdala excitatory': '1.0', 'Cerebellar inhibitory': '0.9', 'Cge interneuron': '0.7', 'Deep-layer corticothalamic and 6b': '1.5', 'Deep-layer intratelencephalic': '0.7', 'Deep-layer near-projecting': '0.7', 'Eccentric medium spiny neuron': '0.6', 'Hippocampal ca1-3': '1.9', 'Hippocampal ca4': '1.2', 'Hippocampal dentate gyrus': '1.1', 'Lamp5-lhx6 and chandelier': '0.5', 'Lower rhombic lip': '0.8', 'Mammillary body': '0.6', 'Medium spiny neuron': '0.7', 'Mge interneuron': '1.7', 'Midbrain-derived inhibitory': '0.7', 'Miscellaneous': '0.9', 'Splatter': '3.8', 'Thalamic excitatory': '0.5', 'Upper rhombic lip': '0.8', 'Upper-layer intratelencephalic': '0.6', 'Astrocyte': '4.4', 'Bergmann glia': '0.2', 'Central nervous system macrophage': '0.6', 'Choroid plexus epithelial cell': '52.1', 'Committed oligodendrocyte precursor': '41.5', 'Ependymal cell': '4.8', 'Oligodendrocyte': '53.1', 'Oligodendrocyte precursor cell': '2.4', 'Endothelial cell': '0.7', 'Pericyte': '0.3', 'Vascular associated smooth muscle cell': '0.0', 'Fibroblast': '17.4', 'Leukocyte': '1.1', 'Basophil': '0.0', 'Eosinophil': '0.0', 'Neutrophil': '0.0', 'Classical monocyte': '0.0', 'Non-classical monocyte': '0.0', 'Intermediate monocyte': '0.0', 'T-reg': '2.3', 'GdT-cell': '0.0', 'MAIT T-cell': '0.0', 'Memory CD4 T-cell': '0.0', 'Naive CD4 T-cell': '0.1', 'Memory CD8 T-cell': '0.2', 'Naive CD8 T-cell': '0.3', 'Memory B-cell': '0.0', 'Naive B-cell': '0.1', 'Plasmacytoid DC': '46.6', 'Myeloid DC': '8.5', 'NK-cell': '0.1', 'Total PBMC': '0.7', 'Vd2 gdTCR': '0.0', 'Memory CD4 T-cell Th1\\/Th17': '0.1', 'Memory CD4 T-cell Th17': '0.2', 'Memory CD4 T-cell Th2': '2.9', 'Non-Vd2 gdTCR': '0.1', 'Memory CD4 T-cell Th1': '0.3', 'Memory CD4 T-cell TFH': '0.5', 'Terminal effector memory CD4 T-cell': '0.0', 'Central memory CD8 T-cell': '4.8', 'Effector memory CD8 T-cell': '0.0', 'Terminal effector memory CD8 T-cell': '0.6', 'Non-switched memory B-cell': '0.0', 'Plasmablast': '3.3', 'Switched memory B-cell': '0.0', 'Exhausted memory B-cell': '0.7', 'Progenitor cell': '2.3', 'Memory T-reg': '1.3', 'Naive CD4 T-cell activated': '0.3', 'Naive CD8 T-cell activated': '0.6', 'Naive T-reg': '0.1'} | 1O6S, 2O72, 2OMT, 2OMU, 2OMV, 2OMX, 2OMY, 2OMZ, 3FF7, 3FF8, 3L6X, 3L6Y, 4ZT1, 4ZTE, 6CXY, 6OLE, 6OLF, 6OLG, 6VEL, 7STZ, 8H62 | {'Adipose Tissue': 1.2125261088039867, 'Adrenal Gland': 0.1914223992248062, 'Bladder': 39.2033519047619, 'Blood': 1.340954264800861, 'Blood Vessel': 0.3121561692883895, 'Brain': 0.8550442199091597, 'Breast': 38.54918344226579, 'Cervix Uteri': 23.539115789473684, 'Colon': 43.41292142490372, 'Esophagus': 53.97513367404844, 'Fallopian Tube': 14.900277777777776, 'Heart': 0.119140469221835, 'Kidney': 25.040449438202245, 'Liver': 26.60802654867257, 'Lung': 35.447986366782004, 'Muscle': 0.1378936151930261, 'Nerve': 17.518468982229404, 'Ovary': 3.6515122222222223, 'Pancreas': 56.89676829268293, 'Pituitary': 24.68741660777385, 'Prostate': 61.279967346938776, 'Salivary Gland': 92.01685185185184, 'Skin': 79.77571720232172, 'Small Intestine': 71.7519320855615, 'Spleen': 10.061029045643156, 'Stomach': 58.07813805013927, 'Testis': 0.8144204986149585, 'Thyroid': 135.176797856049, 'Uterus': 1.442593943661972, 'Vagina': 86.52345512820513} | AURKB | MAQKENSYPWPYGRQTAPSGLSTLPQRVLRKEPVTPSALVLMSRSNVQPTAAPGQKVMENSSGTPDILTRHFTIDDFEIGRPLGKALLCLWPEASSVSSPSHPNILRLYNYFYDRRRIYLILEYAPRGELYKELQKSCTFDEQRTATIMEELADALMYCHGKKVIHRDIKPENLLLGLKGELKIADFGWSVHAPSLRRKTMCGTLDYLPPEMIEGRMHNEKVDLWCIGVLCYELLVGNPPFESASHNETYRRIVKVDLKFPASVPMGAQDLISKLLRHNPSERLPLAQVSAHPWVRANSRRVLPPSALQSVA | Homo sapiens | null | Not found | {} | null | {'Adipose Tissue': 1.4738776162790697, 'Adrenal Gland': 1.6113024031007752, 'Bladder': 1.5387504761904762, 'Blood': 32.23255343379979, 'Blood Vessel': 1.0121387715355803, 'Brain': 0.1394279114307343, 'Breast': 1.4640847494553375, 'Cervix Uteri': 2.2752526315789474, 'Colon': 5.039736046213094, 'Esophagus': 9.005606948096885, 'Fallopian Tube': 0.6781999999999999, 'Heart': 0.4651034030197444, 'Kidney': 1.0157044943820224, 'Liver': 1.304555442477876, 'Lung': 4.480531903114187, 'Muscle': 0.152341706102117, 'Nerve': 43.200933441033925, 'Ovary': 1.0221724444444444, 'Pancreas': 0.3695434451219512, 'Pituitary': 0.3656560424028268, 'Prostate': 1.416055224489796, 'Salivary Gland': 3.496744135802469, 'Skin': 17.819689662797124, 'Small Intestine': 12.2027256684492, 'Spleen': 16.24776763485477, 'Stomach': 4.78460852367688, 'Testis': 2.3102357340720223, 'Thyroid': 1.0494922817764163, 'Uterus': 0.8543154929577464, 'Vagina': 9.050123076923075} | [39.93, 46.46, 52.9, 44.21, 41.4, 39.93, 35.91, 38.61, 36.44, 36.25, 34.86, 32.82, 32.01, 32.75, 31.69, 35.64, 36.35, 34.66, 33.32, 32.71, 35.01, 30.17, 37.05, 36.53, 48.19, 58.22, 64.94, 73.22, 78.33, 82.63, 85.79, 89.39, 87.89, 85.58, 83.93, 89.1, 89.27, 90.66, 87.86, 86.2, 82.97, 72.75, 73.3, 76.44, 82.38, 82.41, 79.49, 86.6, 76.32, 85.48, 88.69, 84.35, 87.75, 90.57, 88.72, 89.46, 87.48, 85.3, 81.72, 79.46, 77.26, 69.01, 67.1, 62.83, 67.71, 74.96, 82.95, 86.74, 86.35, 86.49, 84.6, 85.99, 85.64, 87.19, 89.23, 89.3, 90.62, 84.21, 85.42, 83.34, 84.28, 89.8, 89.78, 87.53, 87.64, 85.98, 81.31, 80.85, 78.74, 80.15, 70.67, 69.91, 72.91, 77.13, 83.26, 84.67, 90.36, 89.7, 92.74, 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Forms a ternary complex composed of ADAM10, CADH1 and EPHA4, | null | null | KLRG1, SPEF1, DLGAP5, AJAP1, RAPGEF2, RAB8B, PIP5K1C, PKP2, TRPV4, CTNNB1, CAV1, DDR1, TBC1D2, CTNNA1, JUP, CTNND1, PSEN1, LIMA1, CDH1, JUP, ADAM10, CADH1 , EPHA4, | null | null | null | null | Homodimer | null | 79.91949 | 0.474025 | null | null | 1,950 |
P12830 | Q96GD4-5 | null | degron_data | CDH1 | MGPWSRSLSALLLLLQVSSWLCQEPEPCHPGFDAESYTFTVPRRHLERGRVLGRVNFEDCTGRQRTAYFSLDTRFKVGTDGVITVKRPLRFHNPQIHFLVYAWDSTYRKFSTKVTLNTVGHHHRPPPHQASVSGIQAELLTFPNSSPGLRRQKRDWVIPPISCPENEKGPFPKNLVQIKSNKDKEGKVFYSITGQGADTPPVGVFIIERETGWLKVTEPLDRERIATYTLFSHAVSSNGNAVEDPMEILITVTDQNDNKPEFTQEVFKGSVMEGALPGTSVMEVTATDADDDVNTYNAAIAYTILSQDPELPDKNMFTINRNTGVISVVTTGLDRESFPTYTLVVQAADLQGEGLSTTATAVITVTDTNDNPPIFNPTTYKGQVPENEANVVITTLKVTDADAPNTPAWEAVYTILNDDGGQFVVTTNPVNNDGILKTAKGLDFEAKQQYILHVAVTNVVPFEVSLTTSTATVTVDVLDVNEAPIFVPPEKRVEVSEDFGVGQEITSYTAQEPDTFMEQKITYRIWRDTANWLEINPDTGAISTRAELDREDFEHVKNSTYTALIIATDNGSPVATGTGTLLLILSDVNDNAPIPEPRTIFFCERNPKPQVINIIDADLPPNTSPFTAELTHGASANWTIQYNDPTQESIILKPKMALEVGDYKINLKLMDNQNKDQVTTLEVSVCDCEGAAGVCRKAQPVEAGLQIPAILGILGGILALLILILLLLLFLRRRAVVKEPLLPPEDDTRDNVYYYDEEGGGEEDQDFDLSQLHRGLDARPEVTRNDVAPTLMSVPRYLPRPANPDEIGNFIDENLKAADTDPTAPPYDSLLVFDYEGSGSEAASLSSLNSSESDKDQDYDYLNEWGNRFKKLADMYGGGEDD | Homo sapiens | Cell junction, adherens junction, Cell membrane, Endosome, Golgi apparatus, trans-Golgi network, Cytoplasm, Cell junction, desmosome | Tissue enhanced (parathyroid) | {'Ciliated cells': '119.1', 'Basal respiratory cells': '71.1', 'Club cells': '97.3', 'Ionocytes': '81.0', 'Mucus glandular cells': '155.0', 'Serous glandular cells': '67.8', 'Gastric mucus-secreting cells': '133.2', 'Proximal enterocytes': '140.9', 'Paneth cells': '125.1', 'Distal enterocytes': '307.5', 'Intestinal goblet cells': '173.5', 'Exocrine glandular cells': '-0.605', 'Basal prostatic cells': '68.3', 'Prostatic glandular cells': '186.7', 'Breast glandular cells': '0.773', 'Breast myoepithelial cells': '0.700', 'Glandular and luminal cells': '313.0', 'Secretory cells': '82.3', 'Basal keratinocytes': '102.5', 'Suprabasal keratinocytes': '162.6', 'Basal squamous epithelial cells': '51.0', 'Squamous epithelial cells': '106.9', 'Alveolar cells type 1': '0.437', 'Alveolar cells type 2': '0.706', 'Salivary duct cells': '95.9', 'Ductal cells': '0.541', 'Hepatocytes': '0.600', 'Cholangiocytes': '129.7', 'Proximal tubular cells': '0.042', 'Distal tubular cells': '0.0', 'Collecting duct cells': '143.9', 'Mesothelial cells': '0.799', 'Sertoli cells': '0.252', 'Granulosa cells': '12.9', 'Enteroendocrine cells': '92.4', 'Pancreatic endocrine cells': '78.1', 'Leydig cells': '0.264', 'Excitatory neurons': '0.7', 'Inhibitory neurons': '1.3', 'Cone photoreceptor cells': '0.0', 'Rod photoreceptor cells': '0.0', 'Bipolar cells': '0.2', 'Horizontal cells': '0.6', 'Astrocytes': '0.6', 'Oligodendrocyte precursor cells': '0.5', 'Oligodendrocytes': '29.9', 'Microglial cells': '0.9', 'Muller glia cells': '0.1', 'Schwann cells': '0.131', 'Spermatogonia': '0.392', 'Spermatocytes': '0.193', 'Early spermatids': '-0.217', 'Late spermatids': '-0.290', 'Oocytes': '16.9', 'Cytotrophoblasts': '119.2', 'Syncytiotrophoblasts': '45.0', 'Extravillous trophoblasts': '24.9', 'Endothelial cells': '6.1', 'Lymphatic endothelial cells': '0.4', 'Cardiomyocytes': '0.135', 'Skeletal myocytes': '0.107', 'Smooth muscle cells': '5.8', 'Adipocytes': '2.1', 'Melanocytes': '0.335', 'Fibroblasts': '6.5', 'Peritubular cells': '0.210', 'Endometrial stromal cells': '27.7', 'Ovarian stromal cells': '0.7', 'Undifferentiated cells': '101.6', 'T-cells': '2.9', 'B-cells': '4.4', 'Plasma cells': '6.1', 'Nk-cells': '0.0', 'Granulocytes': '8.4', 'Monocytes': '0.0', 'Macrophages': '6.0', 'Hofbauer cells': '4.3', 'Kupffer cells': '1.0', 'Dendritic cells': '5.9', 'Langerhans cells': '0.304', 'Erythroid cells': '0.036', 'Adipocytes (Subcutaneous)': '-0.081', 'Adipocytes (Visceral)': '-0.209', 'Breast glandular cells (progenitors)': '0.538', 'Adipocytes (Breast)': '-0.689', 'Colon enterocytes': '0.790', 'Colon enteroendocrine cells': '0.112', 'Enteric glia cells': '-0.048', 'Mitotic cells (Colon)': '0.299', 'Mitotic cells (Heart)': '0.120', 'Podocytes': '-0.118', 'Ascending Loop of Henle cells': '0.475', 'Intercalated cells': '0.212', 'Cholangiocyte': '0.090', 'NK-cells (Liver)': '-0.005', 'Respiratory ciliated cells': '-0.012', 'Mitotic cells (Lung)': '0.071', 'NK-cells (Lung)': '-0.266', 'B-cells (Lung)': '-0.296', 'Alpha cells': '0.270', 'Beta cells': '0.152', 'Prostate glandular cells': '0.764', 'Prostate basal glandular cells': '0.540', 'Urothelial cells': '0.205', 'Keratinocyte (other)': '0.510', 'Keratinocyte (granular)': '0.055', 'Hair cortex cells': '0.080', 'Inner root sheath cells': '0.131', 'Outer root sheath cells': '0.175', 'Sebaceous gland cells': '0.156', 'Eccrine sweat gland cells': '-0.207', 'Adipocytes (Skin)': '-0.244', 'Mitotic cells (Skin)': '0.442', 'Parietal cells': '0.654', 'Chief cells': '0.649', 'Gastric mucous cells': '0.781', 'Gastric enteroendocrine cells': '0.590', 'Mitotic cells (Stomach)': '0.445', 'Parafollicular cells': '0.173', 'Thyroid glandular cells': '0.865', 'Mitotic cells (Thyroid)': '-0.081', 'Adrenal cortex cells': '0.051', 'Adrenal medulla cells': '0.087', 'Mitotic cells (Adrenal gland)': '0.072', 'Minor salivary glandular cells': '0.371', 'Minor salivary gland ductal cells': '-0.142', 'Minor salivary gland basal cells': '0.582', 'Mitotic cells (Minor salivary gland)': '0.567', 'Adipocytes (Minor salivary gland)': '0.050', 'Somatotropes': '0.121', 'Lactotropes': '0.322', 'Gonadotropes': '0.330', 'Corticotropes': '0.180', 'Thyrotropes': '0.496', 'Undifferentiated cells (Pituitary gland)': '-0.108', 'Mitotic cells (Spleen)': '-0.228', 'Platelets': '-0.050', 'Erythrocytes': '-0.158', 'Hematopoietic stem cells': '-0.211', 'B-cells (Spleen)': '0.266', 'NK-cells (Spleen)': '0.309', 'Amygdala excitatory': '1.0', 'Cerebellar inhibitory': '0.9', 'Cge interneuron': '0.7', 'Deep-layer corticothalamic and 6b': '1.5', 'Deep-layer intratelencephalic': '0.7', 'Deep-layer near-projecting': '0.7', 'Eccentric medium spiny neuron': '0.6', 'Hippocampal ca1-3': '1.9', 'Hippocampal ca4': '1.2', 'Hippocampal dentate gyrus': '1.1', 'Lamp5-lhx6 and chandelier': '0.5', 'Lower rhombic lip': '0.8', 'Mammillary body': '0.6', 'Medium spiny neuron': '0.7', 'Mge interneuron': '1.7', 'Midbrain-derived inhibitory': '0.7', 'Miscellaneous': '0.9', 'Splatter': '3.8', 'Thalamic excitatory': '0.5', 'Upper rhombic lip': '0.8', 'Upper-layer intratelencephalic': '0.6', 'Astrocyte': '4.4', 'Bergmann glia': '0.2', 'Central nervous system macrophage': '0.6', 'Choroid plexus epithelial cell': '52.1', 'Committed oligodendrocyte precursor': '41.5', 'Ependymal cell': '4.8', 'Oligodendrocyte': '53.1', 'Oligodendrocyte precursor cell': '2.4', 'Endothelial cell': '0.7', 'Pericyte': '0.3', 'Vascular associated smooth muscle cell': '0.0', 'Fibroblast': '17.4', 'Leukocyte': '1.1', 'Basophil': '0.0', 'Eosinophil': '0.0', 'Neutrophil': '0.0', 'Classical monocyte': '0.0', 'Non-classical monocyte': '0.0', 'Intermediate monocyte': '0.0', 'T-reg': '2.3', 'GdT-cell': '0.0', 'MAIT T-cell': '0.0', 'Memory CD4 T-cell': '0.0', 'Naive CD4 T-cell': '0.1', 'Memory CD8 T-cell': '0.2', 'Naive CD8 T-cell': '0.3', 'Memory B-cell': '0.0', 'Naive B-cell': '0.1', 'Plasmacytoid DC': '46.6', 'Myeloid DC': '8.5', 'NK-cell': '0.1', 'Total PBMC': '0.7', 'Vd2 gdTCR': '0.0', 'Memory CD4 T-cell Th1\\/Th17': '0.1', 'Memory CD4 T-cell Th17': '0.2', 'Memory CD4 T-cell Th2': '2.9', 'Non-Vd2 gdTCR': '0.1', 'Memory CD4 T-cell Th1': '0.3', 'Memory CD4 T-cell TFH': '0.5', 'Terminal effector memory CD4 T-cell': '0.0', 'Central memory CD8 T-cell': '4.8', 'Effector memory CD8 T-cell': '0.0', 'Terminal effector memory CD8 T-cell': '0.6', 'Non-switched memory B-cell': '0.0', 'Plasmablast': '3.3', 'Switched memory B-cell': '0.0', 'Exhausted memory B-cell': '0.7', 'Progenitor cell': '2.3', 'Memory T-reg': '1.3', 'Naive CD4 T-cell activated': '0.3', 'Naive CD8 T-cell activated': '0.6', 'Naive T-reg': '0.1'} | 1O6S, 2O72, 2OMT, 2OMU, 2OMV, 2OMX, 2OMY, 2OMZ, 3FF7, 3FF8, 3L6X, 3L6Y, 4ZT1, 4ZTE, 6CXY, 6OLE, 6OLF, 6OLG, 6VEL, 7STZ, 8H62 | {'Adipose Tissue': 1.2125261088039867, 'Adrenal Gland': 0.1914223992248062, 'Bladder': 39.2033519047619, 'Blood': 1.340954264800861, 'Blood Vessel': 0.3121561692883895, 'Brain': 0.8550442199091597, 'Breast': 38.54918344226579, 'Cervix Uteri': 23.539115789473684, 'Colon': 43.41292142490372, 'Esophagus': 53.97513367404844, 'Fallopian Tube': 14.900277777777776, 'Heart': 0.119140469221835, 'Kidney': 25.040449438202245, 'Liver': 26.60802654867257, 'Lung': 35.447986366782004, 'Muscle': 0.1378936151930261, 'Nerve': 17.518468982229404, 'Ovary': 3.6515122222222223, 'Pancreas': 56.89676829268293, 'Pituitary': 24.68741660777385, 'Prostate': 61.279967346938776, 'Salivary Gland': 92.01685185185184, 'Skin': 79.77571720232172, 'Small Intestine': 71.7519320855615, 'Spleen': 10.061029045643156, 'Stomach': 58.07813805013927, 'Testis': 0.8144204986149585, 'Thyroid': 135.176797856049, 'Uterus': 1.442593943661972, 'Vagina': 86.52345512820513} | AURKB | MAQKENSYPWPYGRQTAPSGLSTLPQRVLRKEPVTPSALVLMSRSNVQPTAAPGQKVMENSSGTPDILTRRHFTIDDFEIGRPLGKGKFGNVYLAREKKSHFIVALKVLFKSQIEKEGVEHQLRREIEIQAHLHHPNILRLYNYFYDRRRIYLILEYAPRGELYKELQKSCTFDEQRTATIMEELADALMYCHGKKVIHRDIKPENLLLGLKGELKIADFGWSVHAPSLRRKTMCGTLDYLPPEMIEGRMHNEKVDLWCIGVLCYELLVGNPPFESASHNETYRRIVKVDLKFPASVPMGAQDLISKLLRHNPSERLPLAQVSAHPWVRANSRRVLPPSALQSVA | Homo sapiens | null | Not found | {} | null | {'Adipose Tissue': 1.4738776162790697, 'Adrenal Gland': 1.6113024031007752, 'Bladder': 1.5387504761904762, 'Blood': 32.23255343379979, 'Blood Vessel': 1.0121387715355803, 'Brain': 0.1394279114307343, 'Breast': 1.4640847494553375, 'Cervix Uteri': 2.2752526315789474, 'Colon': 5.039736046213094, 'Esophagus': 9.005606948096885, 'Fallopian Tube': 0.6781999999999999, 'Heart': 0.4651034030197444, 'Kidney': 1.0157044943820224, 'Liver': 1.304555442477876, 'Lung': 4.480531903114187, 'Muscle': 0.152341706102117, 'Nerve': 43.200933441033925, 'Ovary': 1.0221724444444444, 'Pancreas': 0.3695434451219512, 'Pituitary': 0.3656560424028268, 'Prostate': 1.416055224489796, 'Salivary Gland': 3.496744135802469, 'Skin': 17.819689662797124, 'Small Intestine': 12.2027256684492, 'Spleen': 16.24776763485477, 'Stomach': 4.78460852367688, 'Testis': 2.3102357340720223, 'Thyroid': 1.0494922817764163, 'Uterus': 0.8543154929577464, 'Vagina': 9.050123076923075} | [39.93, 46.46, 52.9, 44.21, 41.4, 39.93, 35.91, 38.61, 36.44, 36.25, 34.86, 32.82, 32.01, 32.75, 31.69, 35.64, 36.35, 34.66, 33.32, 32.71, 35.01, 30.17, 37.05, 36.53, 48.19, 58.22, 64.94, 73.22, 78.33, 82.63, 85.79, 89.39, 87.89, 85.58, 83.93, 89.1, 89.27, 90.66, 87.86, 86.2, 82.97, 72.75, 73.3, 76.44, 82.38, 82.41, 79.49, 86.6, 76.32, 85.48, 88.69, 84.35, 87.75, 90.57, 88.72, 89.46, 87.48, 85.3, 81.72, 79.46, 77.26, 69.01, 67.1, 62.83, 67.71, 74.96, 82.95, 86.74, 86.35, 86.49, 84.6, 85.99, 85.64, 87.19, 89.23, 89.3, 90.62, 84.21, 85.42, 83.34, 84.28, 89.8, 89.78, 87.53, 87.64, 85.98, 81.31, 80.85, 78.74, 80.15, 70.67, 69.91, 72.91, 77.13, 83.26, 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Forms a ternary complex composed of ADAM10, CADH1 and EPHA4, | null | null | KLRG1, SPEF1, DLGAP5, AJAP1, RAPGEF2, RAB8B, PIP5K1C, PKP2, TRPV4, CTNNB1, CAV1, DDR1, TBC1D2, CTNNA1, JUP, CTNND1, PSEN1, LIMA1, CDH1, JUP, ADAM10, CADH1 , EPHA4, | null | null | null | null | Homodimer | null | 79.91949 | 0.474025 | null | null | 1,950 |
P12830 | Q96RL1 | null | degron_data | CDH1 | MGPWSRSLSALLLLLQVSSWLCQEPEPCHPGFDAESYTFTVPRRHLERGRVLGRVNFEDCTGRQRTAYFSLDTRFKVGTDGVITVKRPLRFHNPQIHFLVYAWDSTYRKFSTKVTLNTVGHHHRPPPHQASVSGIQAELLTFPNSSPGLRRQKRDWVIPPISCPENEKGPFPKNLVQIKSNKDKEGKVFYSITGQGADTPPVGVFIIERETGWLKVTEPLDRERIATYTLFSHAVSSNGNAVEDPMEILITVTDQNDNKPEFTQEVFKGSVMEGALPGTSVMEVTATDADDDVNTYNAAIAYTILSQDPELPDKNMFTINRNTGVISVVTTGLDRESFPTYTLVVQAADLQGEGLSTTATAVITVTDTNDNPPIFNPTTYKGQVPENEANVVITTLKVTDADAPNTPAWEAVYTILNDDGGQFVVTTNPVNNDGILKTAKGLDFEAKQQYILHVAVTNVVPFEVSLTTSTATVTVDVLDVNEAPIFVPPEKRVEVSEDFGVGQEITSYTAQEPDTFMEQKITYRIWRDTANWLEINPDTGAISTRAELDREDFEHVKNSTYTALIIATDNGSPVATGTGTLLLILSDVNDNAPIPEPRTIFFCERNPKPQVINIIDADLPPNTSPFTAELTHGASANWTIQYNDPTQESIILKPKMALEVGDYKINLKLMDNQNKDQVTTLEVSVCDCEGAAGVCRKAQPVEAGLQIPAILGILGGILALLILILLLLLFLRRRAVVKEPLLPPEDDTRDNVYYYDEEGGGEEDQDFDLSQLHRGLDARPEVTRNDVAPTLMSVPRYLPRPANPDEIGNFIDENLKAADTDPTAPPYDSLLVFDYEGSGSEAASLSSLNSSESDKDQDYDYLNEWGNRFKKLADMYGGGEDD | Homo sapiens | Cell junction, adherens junction, Cell membrane, Endosome, Golgi apparatus, trans-Golgi network, Cytoplasm, Cell junction, desmosome | Tissue enhanced (parathyroid) | {'Ciliated cells': '119.1', 'Basal respiratory cells': '71.1', 'Club cells': '97.3', 'Ionocytes': '81.0', 'Mucus glandular cells': '155.0', 'Serous glandular cells': '67.8', 'Gastric mucus-secreting cells': '133.2', 'Proximal enterocytes': '140.9', 'Paneth cells': '125.1', 'Distal enterocytes': '307.5', 'Intestinal goblet cells': '173.5', 'Exocrine glandular cells': '-0.605', 'Basal prostatic cells': '68.3', 'Prostatic glandular cells': '186.7', 'Breast glandular cells': '0.773', 'Breast myoepithelial cells': '0.700', 'Glandular and luminal cells': '313.0', 'Secretory cells': '82.3', 'Basal keratinocytes': '102.5', 'Suprabasal keratinocytes': '162.6', 'Basal squamous epithelial cells': '51.0', 'Squamous epithelial cells': '106.9', 'Alveolar cells type 1': '0.437', 'Alveolar cells type 2': '0.706', 'Salivary duct cells': '95.9', 'Ductal cells': '0.541', 'Hepatocytes': '0.600', 'Cholangiocytes': '129.7', 'Proximal tubular cells': '0.042', 'Distal tubular cells': '0.0', 'Collecting duct cells': '143.9', 'Mesothelial cells': '0.799', 'Sertoli cells': '0.252', 'Granulosa cells': '12.9', 'Enteroendocrine cells': '92.4', 'Pancreatic endocrine cells': '78.1', 'Leydig cells': '0.264', 'Excitatory neurons': '0.7', 'Inhibitory neurons': '1.3', 'Cone photoreceptor cells': '0.0', 'Rod photoreceptor cells': '0.0', 'Bipolar cells': '0.2', 'Horizontal cells': '0.6', 'Astrocytes': '0.6', 'Oligodendrocyte precursor cells': '0.5', 'Oligodendrocytes': '29.9', 'Microglial cells': '0.9', 'Muller glia cells': '0.1', 'Schwann cells': '0.131', 'Spermatogonia': '0.392', 'Spermatocytes': '0.193', 'Early spermatids': '-0.217', 'Late spermatids': '-0.290', 'Oocytes': '16.9', 'Cytotrophoblasts': '119.2', 'Syncytiotrophoblasts': '45.0', 'Extravillous trophoblasts': '24.9', 'Endothelial cells': '6.1', 'Lymphatic endothelial cells': '0.4', 'Cardiomyocytes': '0.135', 'Skeletal myocytes': '0.107', 'Smooth muscle cells': '5.8', 'Adipocytes': '2.1', 'Melanocytes': '0.335', 'Fibroblasts': '6.5', 'Peritubular cells': '0.210', 'Endometrial stromal cells': '27.7', 'Ovarian stromal cells': '0.7', 'Undifferentiated cells': '101.6', 'T-cells': '2.9', 'B-cells': '4.4', 'Plasma cells': '6.1', 'Nk-cells': '0.0', 'Granulocytes': '8.4', 'Monocytes': '0.0', 'Macrophages': '6.0', 'Hofbauer cells': '4.3', 'Kupffer cells': '1.0', 'Dendritic cells': '5.9', 'Langerhans cells': '0.304', 'Erythroid cells': '0.036', 'Adipocytes (Subcutaneous)': '-0.081', 'Adipocytes (Visceral)': '-0.209', 'Breast glandular cells (progenitors)': '0.538', 'Adipocytes (Breast)': '-0.689', 'Colon enterocytes': '0.790', 'Colon enteroendocrine cells': '0.112', 'Enteric glia cells': '-0.048', 'Mitotic cells (Colon)': '0.299', 'Mitotic cells (Heart)': '0.120', 'Podocytes': '-0.118', 'Ascending Loop of Henle cells': '0.475', 'Intercalated cells': '0.212', 'Cholangiocyte': '0.090', 'NK-cells (Liver)': '-0.005', 'Respiratory ciliated cells': '-0.012', 'Mitotic cells (Lung)': '0.071', 'NK-cells (Lung)': '-0.266', 'B-cells (Lung)': '-0.296', 'Alpha cells': '0.270', 'Beta cells': '0.152', 'Prostate glandular cells': '0.764', 'Prostate basal glandular cells': '0.540', 'Urothelial cells': '0.205', 'Keratinocyte (other)': '0.510', 'Keratinocyte (granular)': '0.055', 'Hair cortex cells': '0.080', 'Inner root sheath cells': '0.131', 'Outer root sheath cells': '0.175', 'Sebaceous gland cells': '0.156', 'Eccrine sweat gland cells': '-0.207', 'Adipocytes (Skin)': '-0.244', 'Mitotic cells (Skin)': '0.442', 'Parietal cells': '0.654', 'Chief cells': '0.649', 'Gastric mucous cells': '0.781', 'Gastric enteroendocrine cells': '0.590', 'Mitotic cells (Stomach)': '0.445', 'Parafollicular cells': '0.173', 'Thyroid glandular cells': '0.865', 'Mitotic cells (Thyroid)': '-0.081', 'Adrenal cortex cells': '0.051', 'Adrenal medulla cells': '0.087', 'Mitotic cells (Adrenal gland)': '0.072', 'Minor salivary glandular cells': '0.371', 'Minor salivary gland ductal cells': '-0.142', 'Minor salivary gland basal cells': '0.582', 'Mitotic cells (Minor salivary gland)': '0.567', 'Adipocytes (Minor salivary gland)': '0.050', 'Somatotropes': '0.121', 'Lactotropes': '0.322', 'Gonadotropes': '0.330', 'Corticotropes': '0.180', 'Thyrotropes': '0.496', 'Undifferentiated cells (Pituitary gland)': '-0.108', 'Mitotic cells (Spleen)': '-0.228', 'Platelets': '-0.050', 'Erythrocytes': '-0.158', 'Hematopoietic stem cells': '-0.211', 'B-cells (Spleen)': '0.266', 'NK-cells (Spleen)': '0.309', 'Amygdala excitatory': '1.0', 'Cerebellar inhibitory': '0.9', 'Cge interneuron': '0.7', 'Deep-layer corticothalamic and 6b': '1.5', 'Deep-layer intratelencephalic': '0.7', 'Deep-layer near-projecting': '0.7', 'Eccentric medium spiny neuron': '0.6', 'Hippocampal ca1-3': '1.9', 'Hippocampal ca4': '1.2', 'Hippocampal dentate gyrus': '1.1', 'Lamp5-lhx6 and chandelier': '0.5', 'Lower rhombic lip': '0.8', 'Mammillary body': '0.6', 'Medium spiny neuron': '0.7', 'Mge interneuron': '1.7', 'Midbrain-derived inhibitory': '0.7', 'Miscellaneous': '0.9', 'Splatter': '3.8', 'Thalamic excitatory': '0.5', 'Upper rhombic lip': '0.8', 'Upper-layer intratelencephalic': '0.6', 'Astrocyte': '4.4', 'Bergmann glia': '0.2', 'Central nervous system macrophage': '0.6', 'Choroid plexus epithelial cell': '52.1', 'Committed oligodendrocyte precursor': '41.5', 'Ependymal cell': '4.8', 'Oligodendrocyte': '53.1', 'Oligodendrocyte precursor cell': '2.4', 'Endothelial cell': '0.7', 'Pericyte': '0.3', 'Vascular associated smooth muscle cell': '0.0', 'Fibroblast': '17.4', 'Leukocyte': '1.1', 'Basophil': '0.0', 'Eosinophil': '0.0', 'Neutrophil': '0.0', 'Classical monocyte': '0.0', 'Non-classical monocyte': '0.0', 'Intermediate monocyte': '0.0', 'T-reg': '2.3', 'GdT-cell': '0.0', 'MAIT T-cell': '0.0', 'Memory CD4 T-cell': '0.0', 'Naive CD4 T-cell': '0.1', 'Memory CD8 T-cell': '0.2', 'Naive CD8 T-cell': '0.3', 'Memory B-cell': '0.0', 'Naive B-cell': '0.1', 'Plasmacytoid DC': '46.6', 'Myeloid DC': '8.5', 'NK-cell': '0.1', 'Total PBMC': '0.7', 'Vd2 gdTCR': '0.0', 'Memory CD4 T-cell Th1\\/Th17': '0.1', 'Memory CD4 T-cell Th17': '0.2', 'Memory CD4 T-cell Th2': '2.9', 'Non-Vd2 gdTCR': '0.1', 'Memory CD4 T-cell Th1': '0.3', 'Memory CD4 T-cell TFH': '0.5', 'Terminal effector memory CD4 T-cell': '0.0', 'Central memory CD8 T-cell': '4.8', 'Effector memory CD8 T-cell': '0.0', 'Terminal effector memory CD8 T-cell': '0.6', 'Non-switched memory B-cell': '0.0', 'Plasmablast': '3.3', 'Switched memory B-cell': '0.0', 'Exhausted memory B-cell': '0.7', 'Progenitor cell': '2.3', 'Memory T-reg': '1.3', 'Naive CD4 T-cell activated': '0.3', 'Naive CD8 T-cell activated': '0.6', 'Naive T-reg': '0.1'} | 1O6S, 2O72, 2OMT, 2OMU, 2OMV, 2OMX, 2OMY, 2OMZ, 3FF7, 3FF8, 3L6X, 3L6Y, 4ZT1, 4ZTE, 6CXY, 6OLE, 6OLF, 6OLG, 6VEL, 7STZ, 8H62 | {'Adipose Tissue': 1.2125261088039867, 'Adrenal Gland': 0.1914223992248062, 'Bladder': 39.2033519047619, 'Blood': 1.340954264800861, 'Blood Vessel': 0.3121561692883895, 'Brain': 0.8550442199091597, 'Breast': 38.54918344226579, 'Cervix Uteri': 23.539115789473684, 'Colon': 43.41292142490372, 'Esophagus': 53.97513367404844, 'Fallopian Tube': 14.900277777777776, 'Heart': 0.119140469221835, 'Kidney': 25.040449438202245, 'Liver': 26.60802654867257, 'Lung': 35.447986366782004, 'Muscle': 0.1378936151930261, 'Nerve': 17.518468982229404, 'Ovary': 3.6515122222222223, 'Pancreas': 56.89676829268293, 'Pituitary': 24.68741660777385, 'Prostate': 61.279967346938776, 'Salivary Gland': 92.01685185185184, 'Skin': 79.77571720232172, 'Small Intestine': 71.7519320855615, 'Spleen': 10.061029045643156, 'Stomach': 58.07813805013927, 'Testis': 0.8144204986149585, 'Thyroid': 135.176797856049, 'Uterus': 1.442593943661972, 'Vagina': 86.52345512820513} | UIMC1 | MPRRKKKVKEVSESRNLEKKDVETTSSVSVKRKRRLEDAFIVISDSDGEEPKEENGLQKTKTKQSNRAKCLAKRKIAQMTEEEQFALALKMSEQEAREVNSQEEEEEELLRKAIAESLNSCRPSDASATRSRPLATGPSSQSHQEKTTDSGLTEGIWQLVPPSLFKGSHISQGNEAEEREEPWDHTEKTEEEPVSGSSGSWDQSSQPVFENVNVKSFDRCTGHSAEHTQCGKPQESTGRGSAFLKAVQGSGDTSRHCLPTLADAKGLQDTGGTVNYFWGIPFCPDGVDPNQYTKVILCQLEVYQKSLKMAQRQLLNKKGFGEPVLPRPPSLIQNECGQGEQASEKNECISEDMGDEDKEERQESRASDWHSKTKDFQESSIKSLKEKLLLEEEPTTSHGQSSQGIVEETSEEGNSVPASQSVAALTSKRSLVLMPESSAEEITVCPETQLSSSETFDLEREVSPGSRDILDGVRIIMADKEVGNKEDAEKEVAISTFSSSNQVSCPLCDQCFPPTKIERHAMYCNGLMEEDTVLTRRQKEAKTKSDSGTAAQTSLDIDKNEKCYLCKSLVPFREYQCHVDSCLQLAKADQGDGPEGSGRACSTVEGKWQQRLKNPKEKGHSEGRLLSFLEQSEHKTSDADIKSSETGAFRVPSPGMEEAGCSREMQSSFTRRDLNESPVKSFVSISEATDCLVDFKKQVTVQPGSRTRTKAGRGRRRKF | Homo sapiens | Nucleus | Low tissue specificity | {'Ciliated cells': '15.9', 'Basal respiratory cells': '11.4', 'Club cells': '12.8', 'Ionocytes': '10.7', 'Mucus glandular cells': '17.2', 'Serous glandular cells': '9.7', 'Gastric mucus-secreting cells': '15.9', 'Proximal enterocytes': '8.8', 'Paneth cells': '5.2', 'Distal enterocytes': '8.3', 'Intestinal goblet cells': '8.0', 'Exocrine glandular cells': '-0.764', 'Basal prostatic cells': '14.5', 'Prostatic glandular cells': '8.2', 'Breast glandular cells': '0.427', 'Breast myoepithelial cells': '0.475', 'Glandular and luminal cells': '25.6', 'Secretory cells': '17.7', 'Basal keratinocytes': '15.3', 'Suprabasal keratinocytes': '12.4', 'Basal squamous epithelial cells': '17.7', 'Squamous epithelial cells': '14.5', 'Alveolar cells type 1': '0.189', 'Alveolar cells type 2': '-0.625', 'Salivary duct cells': '14.7', 'Ductal cells': '0.532', 'Hepatocytes': '0.139', 'Cholangiocytes': '7.6', 'Proximal tubular cells': '0.136', 'Distal tubular cells': '3.1', 'Collecting duct cells': '13.6', 'Mesothelial cells': '0.409', 'Sertoli cells': '-0.102', 'Granulosa cells': '27.7', 'Enteroendocrine cells': '8.7', 'Pancreatic endocrine cells': '6.8', 'Leydig cells': '-0.115', 'Excitatory neurons': '57.5', 'Inhibitory neurons': '51.1', 'Cone photoreceptor cells': '22.1', 'Rod photoreceptor cells': '38.2', 'Bipolar cells': '20.9', 'Horizontal cells': '13.2', 'Astrocytes': '35.0', 'Oligodendrocyte precursor cells': '41.0', 'Oligodendrocytes': '47.6', 'Microglial cells': '42.0', 'Muller glia cells': '10.2', 'Schwann cells': '0.027', 'Spermatogonia': '0.265', 'Spermatocytes': '0.736', 'Early spermatids': '0.538', 'Late spermatids': '0.102', 'Oocytes': '46.3', 'Cytotrophoblasts': '13.9', 'Syncytiotrophoblasts': '6.0', 'Extravillous trophoblasts': '13.5', 'Endothelial cells': '20.2', 'Lymphatic endothelial cells': '34.0', 'Cardiomyocytes': '0.541', 'Skeletal myocytes': '-0.306', 'Smooth muscle cells': '19.9', 'Adipocytes': '24.4', 'Melanocytes': '0.090', 'Fibroblasts': '15.5', 'Peritubular cells': '-0.122', 'Endometrial stromal cells': '25.6', 'Ovarian stromal cells': '21.3', 'Undifferentiated cells': '9.2', 'T-cells': '24.8', 'B-cells': '33.2', 'Plasma cells': '24.7', 'Nk-cells': '28.3', 'Granulocytes': '15.4', 'Monocytes': '21.0', 'Macrophages': '17.2', 'Hofbauer cells': '11.1', 'Kupffer cells': '12.0', 'Dendritic cells': '13.7', 'Langerhans cells': '0.162', 'Erythroid cells': '0.064', 'Adipocytes (Subcutaneous)': '-0.562', 'Adipocytes (Visceral)': '-0.518', 'Breast glandular cells (progenitors)': '0.283', 'Adipocytes (Breast)': '-0.619', 'Colon enterocytes': '-0.249', 'Colon enteroendocrine cells': '0.200', 'Enteric glia cells': '0.272', 'Mitotic cells (Colon)': '-0.232', 'Mitotic cells (Heart)': '0.485', 'Podocytes': '-0.056', 'Ascending Loop of Henle cells': '0.387', 'Intercalated cells': '-0.022', 'Cholangiocyte': '0.360', 'NK-cells (Liver)': '-0.244', 'Respiratory ciliated cells': '0.093', 'Mitotic cells (Lung)': '-0.221', 'NK-cells (Lung)': '0.546', 'B-cells (Lung)': '0.245', 'Alpha cells': '0.334', 'Beta cells': '0.166', 'Prostate glandular cells': '-0.481', 'Prostate basal glandular cells': '0.006', 'Urothelial cells': '0.127', 'Keratinocyte (other)': '0.292', 'Keratinocyte (granular)': '-0.259', 'Hair cortex cells': '-0.177', 'Inner root sheath cells': '-0.094', 'Outer root sheath cells': '0.138', 'Sebaceous gland cells': '-0.161', 'Eccrine sweat gland cells': '-0.004', 'Adipocytes (Skin)': '-0.314', 'Mitotic cells (Skin)': '0.247', 'Parietal cells': '-0.739', 'Chief cells': '-0.595', 'Gastric mucous cells': '-0.450', 'Gastric enteroendocrine cells': '-0.442', 'Mitotic cells (Stomach)': '-0.027', 'Parafollicular cells': '0.073', 'Thyroid glandular cells': '0.157', 'Mitotic cells (Thyroid)': '-0.036', 'Adrenal cortex cells': '0.229', 'Adrenal medulla cells': '-0.188', 'Mitotic cells (Adrenal gland)': '-0.037', 'Minor salivary glandular cells': '0.554', 'Minor salivary gland ductal cells': '0.106', 'Minor salivary gland basal cells': '0.279', 'Mitotic cells (Minor salivary gland)': '0.348', 'Adipocytes (Minor salivary gland)': '0.193', 'Somatotropes': '0.003', 'Lactotropes': '-0.153', 'Gonadotropes': '-0.073', 'Corticotropes': '-0.072', 'Thyrotropes': '0.004', 'Undifferentiated cells (Pituitary gland)': '0.112', 'Mitotic cells (Spleen)': '-0.115', 'Platelets': '-0.164', 'Erythrocytes': '0.131', 'Hematopoietic stem cells': '-0.172', 'B-cells (Spleen)': '0.369', 'NK-cells (Spleen)': '0.315', 'Amygdala excitatory': '97.1', 'Cerebellar inhibitory': '66.4', 'Cge interneuron': '76.5', 'Deep-layer corticothalamic and 6b': '90.6', 'Deep-layer intratelencephalic': '97.8', 'Deep-layer near-projecting': '86.7', 'Eccentric medium spiny neuron': '92.1', 'Hippocampal ca1-3': '96.6', 'Hippocampal ca4': '91.3', 'Hippocampal dentate gyrus': '119.9', 'Lamp5-lhx6 and chandelier': '76.3', 'Lower rhombic lip': '77.5', 'Mammillary body': '91.4', 'Medium spiny neuron': '101.5', 'Mge interneuron': '81.0', 'Midbrain-derived inhibitory': '62.3', 'Miscellaneous': '88.8', 'Splatter': '77.7', 'Thalamic excitatory': '73.4', 'Upper rhombic lip': '105.6', 'Upper-layer intratelencephalic': '93.8', 'Astrocyte': '65.3', 'Bergmann glia': '87.3', 'Central nervous system macrophage': '117.6', 'Choroid plexus epithelial cell': '98.0', 'Committed oligodendrocyte precursor': '71.0', 'Ependymal cell': '87.3', 'Oligodendrocyte': '81.5', 'Oligodendrocyte precursor cell': '81.0', 'Endothelial cell': '119.5', 'Pericyte': '93.2', 'Vascular associated smooth muscle cell': '86.6', 'Fibroblast': '93.5', 'Leukocyte': '106.4', 'Basophil': '30.6', 'Eosinophil': '33.0', 'Neutrophil': '195.9', 'Classical monocyte': '49.1', 'Non-classical monocyte': '24.3', 'Intermediate monocyte': '31.1', 'T-reg': '49.4', 'GdT-cell': '9.1', 'MAIT T-cell': '51.0', 'Memory CD4 T-cell': '10.3', 'Naive CD4 T-cell': '55.7', 'Memory CD8 T-cell': '9.0', 'Naive CD8 T-cell': '47.0', 'Memory B-cell': '11.9', 'Naive B-cell': '63.1', 'Plasmacytoid DC': '41.2', 'Myeloid DC': '40.3', 'NK-cell': '48.9', 'Total PBMC': '42.8', 'Vd2 gdTCR': '40.5', 'Memory CD4 T-cell Th1\\/Th17': '55.8', 'Memory CD4 T-cell Th17': '57.5', 'Memory CD4 T-cell Th2': '54.8', 'Non-Vd2 gdTCR': '50.1', 'Memory CD4 T-cell Th1': '54.8', 'Memory CD4 T-cell TFH': '52.4', 'Terminal effector memory CD4 T-cell': '59.2', 'Central memory CD8 T-cell': '47.9', 'Effector memory CD8 T-cell': '56.2', 'Terminal effector memory CD8 T-cell': '45.4', 'Non-switched memory B-cell': '53.6', 'Plasmablast': '43.4', 'Switched memory B-cell': '64.2', 'Exhausted memory B-cell': '55.9', 'Progenitor cell': '38.8', 'Memory T-reg': '55.3', 'Naive CD4 T-cell activated': '67.8', 'Naive CD8 T-cell activated': '68.0', 'Naive T-reg': '47.1'} | 2MKF, 2MKG, 2N9E, 2RR9 | {'Adipose Tissue': 29.471669435215947, 'Adrenal Gland': 19.93047674418605, 'Bladder': 34.06761904761905, 'Blood': 38.04500107642626, 'Blood Vessel': 38.77668913857678, 'Brain': 11.215991294473884, 'Breast': 30.99220043572985, 'Cervix Uteri': 43.56263157894737, 'Colon': 28.37434017971759, 'Esophagus': 26.38815017301038, 'Fallopian Tube': 36.86666666666667, 'Heart': 11.78745993031359, 'Kidney': 13.648370786516852, 'Liver': 7.790026548672566, 'Lung': 34.13652249134948, 'Muscle': 15.959438356164384, 'Nerve': 37.4926817447496, 'Ovary': 47.37588888888889, 'Pancreas': 11.546228658536585, 'Pituitary': 23.14213780918728, 'Prostate': 28.76812244897959, 'Salivary Gland': 17.39922839506173, 'Skin': 25.01112769485904, 'Small Intestine': 26.423342245989303, 'Spleen': 35.413941908713696, 'Stomach': 18.903136490250695, 'Testis': 96.8357617728532, 'Thyroid': 35.04356049004594, 'Uterus': 47.847605633802814, 'Vagina': 31.31211538461538} | [39.93, 46.46, 52.9, 44.21, 41.4, 39.93, 35.91, 38.61, 36.44, 36.25, 34.86, 32.82, 32.01, 32.75, 31.69, 35.64, 36.35, 34.66, 33.32, 32.71, 35.01, 30.17, 37.05, 36.53, 48.19, 58.22, 64.94, 73.22, 78.33, 82.63, 85.79, 89.39, 87.89, 85.58, 83.93, 89.1, 89.27, 90.66, 87.86, 86.2, 82.97, 72.75, 73.3, 76.44, 82.38, 82.41, 79.49, 86.6, 76.32, 85.48, 88.69, 84.35, 87.75, 90.57, 88.72, 89.46, 87.48, 85.3, 81.72, 79.46, 77.26, 69.01, 67.1, 62.83, 67.71, 74.96, 82.95, 86.74, 86.35, 86.49, 84.6, 85.99, 85.64, 87.19, 89.23, 89.3, 90.62, 84.21, 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Forms a ternary complex composed of ADAM10, CADH1 and EPHA4, | null | null | KLRG1, SPEF1, DLGAP5, AJAP1, RAPGEF2, RAB8B, PIP5K1C, PKP2, TRPV4, CTNNB1, CAV1, DDR1, TBC1D2, CTNNA1, JUP, CTNND1, PSEN1, LIMA1, CDH1, JUP, ADAM10, CADH1 , EPHA4, | null | null | null | null | Homodimer | null | 79.91949 | 0.474025 | 55.347455 | 0.830278 | 975 |
P12830 | Q96RU7 | null | degron_data | CDH1 | MGPWSRSLSALLLLLQVSSWLCQEPEPCHPGFDAESYTFTVPRRHLERGRVLGRVNFEDCTGRQRTAYFSLDTRFKVGTDGVITVKRPLRFHNPQIHFLVYAWDSTYRKFSTKVTLNTVGHHHRPPPHQASVSGIQAELLTFPNSSPGLRRQKRDWVIPPISCPENEKGPFPKNLVQIKSNKDKEGKVFYSITGQGADTPPVGVFIIERETGWLKVTEPLDRERIATYTLFSHAVSSNGNAVEDPMEILITVTDQNDNKPEFTQEVFKGSVMEGALPGTSVMEVTATDADDDVNTYNAAIAYTILSQDPELPDKNMFTINRNTGVISVVTTGLDRESFPTYTLVVQAADLQGEGLSTTATAVITVTDTNDNPPIFNPTTYKGQVPENEANVVITTLKVTDADAPNTPAWEAVYTILNDDGGQFVVTTNPVNNDGILKTAKGLDFEAKQQYILHVAVTNVVPFEVSLTTSTATVTVDVLDVNEAPIFVPPEKRVEVSEDFGVGQEITSYTAQEPDTFMEQKITYRIWRDTANWLEINPDTGAISTRAELDREDFEHVKNSTYTALIIATDNGSPVATGTGTLLLILSDVNDNAPIPEPRTIFFCERNPKPQVINIIDADLPPNTSPFTAELTHGASANWTIQYNDPTQESIILKPKMALEVGDYKINLKLMDNQNKDQVTTLEVSVCDCEGAAGVCRKAQPVEAGLQIPAILGILGGILALLILILLLLLFLRRRAVVKEPLLPPEDDTRDNVYYYDEEGGGEEDQDFDLSQLHRGLDARPEVTRNDVAPTLMSVPRYLPRPANPDEIGNFIDENLKAADTDPTAPPYDSLLVFDYEGSGSEAASLSSLNSSESDKDQDYDYLNEWGNRFKKLADMYGGGEDD | Homo sapiens | Cell junction, adherens junction, Cell membrane, Endosome, Golgi apparatus, trans-Golgi network, Cytoplasm, Cell junction, desmosome | Tissue enhanced (parathyroid) | {'Ciliated cells': '119.1', 'Basal respiratory cells': '71.1', 'Club cells': '97.3', 'Ionocytes': '81.0', 'Mucus glandular cells': '155.0', 'Serous glandular cells': '67.8', 'Gastric mucus-secreting cells': '133.2', 'Proximal enterocytes': '140.9', 'Paneth cells': '125.1', 'Distal enterocytes': '307.5', 'Intestinal goblet cells': '173.5', 'Exocrine glandular cells': '-0.605', 'Basal prostatic cells': '68.3', 'Prostatic glandular cells': '186.7', 'Breast glandular cells': '0.773', 'Breast myoepithelial cells': '0.700', 'Glandular and luminal cells': '313.0', 'Secretory cells': '82.3', 'Basal keratinocytes': '102.5', 'Suprabasal keratinocytes': '162.6', 'Basal squamous epithelial cells': '51.0', 'Squamous epithelial cells': '106.9', 'Alveolar cells type 1': '0.437', 'Alveolar cells type 2': '0.706', 'Salivary duct cells': '95.9', 'Ductal cells': '0.541', 'Hepatocytes': '0.600', 'Cholangiocytes': '129.7', 'Proximal tubular cells': '0.042', 'Distal tubular cells': '0.0', 'Collecting duct cells': '143.9', 'Mesothelial cells': '0.799', 'Sertoli cells': '0.252', 'Granulosa cells': '12.9', 'Enteroendocrine cells': '92.4', 'Pancreatic endocrine cells': '78.1', 'Leydig cells': '0.264', 'Excitatory neurons': '0.7', 'Inhibitory neurons': '1.3', 'Cone photoreceptor cells': '0.0', 'Rod photoreceptor cells': '0.0', 'Bipolar cells': '0.2', 'Horizontal cells': '0.6', 'Astrocytes': '0.6', 'Oligodendrocyte precursor cells': '0.5', 'Oligodendrocytes': '29.9', 'Microglial cells': '0.9', 'Muller glia cells': '0.1', 'Schwann cells': '0.131', 'Spermatogonia': '0.392', 'Spermatocytes': '0.193', 'Early spermatids': '-0.217', 'Late spermatids': '-0.290', 'Oocytes': '16.9', 'Cytotrophoblasts': '119.2', 'Syncytiotrophoblasts': '45.0', 'Extravillous trophoblasts': '24.9', 'Endothelial cells': '6.1', 'Lymphatic endothelial cells': '0.4', 'Cardiomyocytes': '0.135', 'Skeletal myocytes': '0.107', 'Smooth muscle cells': '5.8', 'Adipocytes': '2.1', 'Melanocytes': '0.335', 'Fibroblasts': '6.5', 'Peritubular cells': '0.210', 'Endometrial stromal cells': '27.7', 'Ovarian stromal cells': '0.7', 'Undifferentiated cells': '101.6', 'T-cells': '2.9', 'B-cells': '4.4', 'Plasma cells': '6.1', 'Nk-cells': '0.0', 'Granulocytes': '8.4', 'Monocytes': '0.0', 'Macrophages': '6.0', 'Hofbauer cells': '4.3', 'Kupffer cells': '1.0', 'Dendritic cells': '5.9', 'Langerhans cells': '0.304', 'Erythroid cells': '0.036', 'Adipocytes (Subcutaneous)': '-0.081', 'Adipocytes (Visceral)': '-0.209', 'Breast glandular cells (progenitors)': '0.538', 'Adipocytes (Breast)': '-0.689', 'Colon enterocytes': '0.790', 'Colon enteroendocrine cells': '0.112', 'Enteric glia cells': '-0.048', 'Mitotic cells (Colon)': '0.299', 'Mitotic cells (Heart)': '0.120', 'Podocytes': '-0.118', 'Ascending Loop of Henle cells': '0.475', 'Intercalated cells': '0.212', 'Cholangiocyte': '0.090', 'NK-cells (Liver)': '-0.005', 'Respiratory ciliated cells': '-0.012', 'Mitotic cells (Lung)': '0.071', 'NK-cells (Lung)': '-0.266', 'B-cells (Lung)': '-0.296', 'Alpha cells': '0.270', 'Beta cells': '0.152', 'Prostate glandular cells': '0.764', 'Prostate basal glandular cells': '0.540', 'Urothelial cells': '0.205', 'Keratinocyte (other)': '0.510', 'Keratinocyte (granular)': '0.055', 'Hair cortex cells': '0.080', 'Inner root sheath cells': '0.131', 'Outer root sheath cells': '0.175', 'Sebaceous gland cells': '0.156', 'Eccrine sweat gland cells': '-0.207', 'Adipocytes (Skin)': '-0.244', 'Mitotic cells (Skin)': '0.442', 'Parietal cells': '0.654', 'Chief cells': '0.649', 'Gastric mucous cells': '0.781', 'Gastric enteroendocrine cells': '0.590', 'Mitotic cells (Stomach)': '0.445', 'Parafollicular cells': '0.173', 'Thyroid glandular cells': '0.865', 'Mitotic cells (Thyroid)': '-0.081', 'Adrenal cortex cells': '0.051', 'Adrenal medulla cells': '0.087', 'Mitotic cells (Adrenal gland)': '0.072', 'Minor salivary glandular cells': '0.371', 'Minor salivary gland ductal cells': '-0.142', 'Minor salivary gland basal cells': '0.582', 'Mitotic cells (Minor salivary gland)': '0.567', 'Adipocytes (Minor salivary gland)': '0.050', 'Somatotropes': '0.121', 'Lactotropes': '0.322', 'Gonadotropes': '0.330', 'Corticotropes': '0.180', 'Thyrotropes': '0.496', 'Undifferentiated cells (Pituitary gland)': '-0.108', 'Mitotic cells (Spleen)': '-0.228', 'Platelets': '-0.050', 'Erythrocytes': '-0.158', 'Hematopoietic stem cells': '-0.211', 'B-cells (Spleen)': '0.266', 'NK-cells (Spleen)': '0.309', 'Amygdala excitatory': '1.0', 'Cerebellar inhibitory': '0.9', 'Cge interneuron': '0.7', 'Deep-layer corticothalamic and 6b': '1.5', 'Deep-layer intratelencephalic': '0.7', 'Deep-layer near-projecting': '0.7', 'Eccentric medium spiny neuron': '0.6', 'Hippocampal ca1-3': '1.9', 'Hippocampal ca4': '1.2', 'Hippocampal dentate gyrus': '1.1', 'Lamp5-lhx6 and chandelier': '0.5', 'Lower rhombic lip': '0.8', 'Mammillary body': '0.6', 'Medium spiny neuron': '0.7', 'Mge interneuron': '1.7', 'Midbrain-derived inhibitory': '0.7', 'Miscellaneous': '0.9', 'Splatter': '3.8', 'Thalamic excitatory': '0.5', 'Upper rhombic lip': '0.8', 'Upper-layer intratelencephalic': '0.6', 'Astrocyte': '4.4', 'Bergmann glia': '0.2', 'Central nervous system macrophage': '0.6', 'Choroid plexus epithelial cell': '52.1', 'Committed oligodendrocyte precursor': '41.5', 'Ependymal cell': '4.8', 'Oligodendrocyte': '53.1', 'Oligodendrocyte precursor cell': '2.4', 'Endothelial cell': '0.7', 'Pericyte': '0.3', 'Vascular associated smooth muscle cell': '0.0', 'Fibroblast': '17.4', 'Leukocyte': '1.1', 'Basophil': '0.0', 'Eosinophil': '0.0', 'Neutrophil': '0.0', 'Classical monocyte': '0.0', 'Non-classical monocyte': '0.0', 'Intermediate monocyte': '0.0', 'T-reg': '2.3', 'GdT-cell': '0.0', 'MAIT T-cell': '0.0', 'Memory CD4 T-cell': '0.0', 'Naive CD4 T-cell': '0.1', 'Memory CD8 T-cell': '0.2', 'Naive CD8 T-cell': '0.3', 'Memory B-cell': '0.0', 'Naive B-cell': '0.1', 'Plasmacytoid DC': '46.6', 'Myeloid DC': '8.5', 'NK-cell': '0.1', 'Total PBMC': '0.7', 'Vd2 gdTCR': '0.0', 'Memory CD4 T-cell Th1\\/Th17': '0.1', 'Memory CD4 T-cell Th17': '0.2', 'Memory CD4 T-cell Th2': '2.9', 'Non-Vd2 gdTCR': '0.1', 'Memory CD4 T-cell Th1': '0.3', 'Memory CD4 T-cell TFH': '0.5', 'Terminal effector memory CD4 T-cell': '0.0', 'Central memory CD8 T-cell': '4.8', 'Effector memory CD8 T-cell': '0.0', 'Terminal effector memory CD8 T-cell': '0.6', 'Non-switched memory B-cell': '0.0', 'Plasmablast': '3.3', 'Switched memory B-cell': '0.0', 'Exhausted memory B-cell': '0.7', 'Progenitor cell': '2.3', 'Memory T-reg': '1.3', 'Naive CD4 T-cell activated': '0.3', 'Naive CD8 T-cell activated': '0.6', 'Naive T-reg': '0.1'} | 1O6S, 2O72, 2OMT, 2OMU, 2OMV, 2OMX, 2OMY, 2OMZ, 3FF7, 3FF8, 3L6X, 3L6Y, 4ZT1, 4ZTE, 6CXY, 6OLE, 6OLF, 6OLG, 6VEL, 7STZ, 8H62 | {'Adipose Tissue': 1.2125261088039867, 'Adrenal Gland': 0.1914223992248062, 'Bladder': 39.2033519047619, 'Blood': 1.340954264800861, 'Blood Vessel': 0.3121561692883895, 'Brain': 0.8550442199091597, 'Breast': 38.54918344226579, 'Cervix Uteri': 23.539115789473684, 'Colon': 43.41292142490372, 'Esophagus': 53.97513367404844, 'Fallopian Tube': 14.900277777777776, 'Heart': 0.119140469221835, 'Kidney': 25.040449438202245, 'Liver': 26.60802654867257, 'Lung': 35.447986366782004, 'Muscle': 0.1378936151930261, 'Nerve': 17.518468982229404, 'Ovary': 3.6515122222222223, 'Pancreas': 56.89676829268293, 'Pituitary': 24.68741660777385, 'Prostate': 61.279967346938776, 'Salivary Gland': 92.01685185185184, 'Skin': 79.77571720232172, 'Small Intestine': 71.7519320855615, 'Spleen': 10.061029045643156, 'Stomach': 58.07813805013927, 'Testis': 0.8144204986149585, 'Thyroid': 135.176797856049, 'Uterus': 1.442593943661972, 'Vagina': 86.52345512820513} | TRIB3 | MRATPLAAPAGSLSRKKRLELDDNLDTERPVQKRARSGPQPRLPPCLLPLSPPTAPDRATAVATASRLGPYVLLEPEEGGRAYQALHCPTGTEYTCKVYPVQEALAVLEPYARLPPHKHVARPTEVLAGTQLLYAFFTRTHGDMHSLVRSRHRIPEPEAAVLFRQMATALAHCHQHGLVLRDLKLCRFVFADRERKKLVLENLEDSCVLTGPDDSLWDKHACPAYVGPEILSSRASYSGKAADVWSLGVALFTMLAGHYPFQDSEPVLLFGKIRRGAYALPAGLSAPARCLVRCLLRREPAERLTATGILLHPWLRQDPMPLAPTRSHLWEAAQVVPDGLGLDEAREEEGDREVVLYG | Homo sapiens | Nucleus | Tissue enhanced (liver) | {'Ciliated cells': '1.8', 'Basal respiratory cells': '19.1', 'Club cells': '7.7', 'Ionocytes': '10.3', 'Mucus glandular cells': '3.2', 'Serous glandular cells': '3.1', 'Gastric mucus-secreting cells': '0.0', 'Proximal enterocytes': '0.0', 'Paneth cells': '4.5', 'Distal enterocytes': '3.1', 'Intestinal goblet cells': '7.9', 'Exocrine glandular cells': '-0.585', 'Basal prostatic cells': '6.8', 'Prostatic glandular cells': '7.6', 'Breast glandular cells': '0.516', 'Breast myoepithelial cells': '0.190', 'Glandular and luminal cells': '3.2', 'Secretory cells': '0.4', 'Basal keratinocytes': '4.5', 'Suprabasal keratinocytes': '6.3', 'Basal squamous epithelial cells': '2.9', 'Squamous epithelial cells': '3.7', 'Alveolar cells type 1': '-0.097', 'Alveolar cells type 2': '0.445', 'Salivary duct cells': '1.6', 'Ductal cells': '0.472', 'Hepatocytes': '-0.068', 'Cholangiocytes': '11.4', 'Proximal tubular cells': '0.017', 'Distal tubular cells': '0.0', 'Collecting duct cells': '3.9', 'Mesothelial cells': '-0.012', 'Sertoli cells': '0.384', 'Granulosa cells': '2.8', 'Enteroendocrine cells': '3.3', 'Pancreatic endocrine cells': '15.3', 'Leydig cells': '0.459', 'Excitatory neurons': '2.1', 'Inhibitory neurons': '2.9', 'Cone photoreceptor cells': '5.1', 'Rod photoreceptor cells': '5.7', 'Bipolar cells': '5.7', 'Horizontal cells': '2.5', 'Astrocytes': '0.3', 'Oligodendrocyte precursor cells': '0.9', 'Oligodendrocytes': '0.6', 'Microglial cells': '0.0', 'Muller glia cells': '1.0', 'Schwann cells': '0.017', 'Spermatogonia': '0.357', 'Spermatocytes': '0.047', 'Early spermatids': '-0.377', 'Late spermatids': '-0.472', 'Oocytes': '1.5', 'Cytotrophoblasts': '14.5', 'Syncytiotrophoblasts': '7.5', 'Extravillous trophoblasts': '4.8', 'Endothelial cells': '8.7', 'Lymphatic endothelial cells': '15.3', 'Cardiomyocytes': '-0.226', 'Skeletal myocytes': '0.021', 'Smooth muscle cells': '3.7', 'Adipocytes': '7.4', 'Melanocytes': '0.009', 'Fibroblasts': '5.1', 'Peritubular cells': '0.319', 'Endometrial stromal cells': '1.4', 'Ovarian stromal cells': '2.1', 'Undifferentiated cells': '4.9', 'T-cells': '5.5', 'B-cells': '6.5', 'Plasma cells': '7.8', 'Nk-cells': '8.3', 'Granulocytes': '7.1', 'Monocytes': '3.5', 'Macrophages': '3.4', 'Hofbauer cells': '6.3', 'Kupffer cells': '7.2', 'Dendritic cells': '0.0', 'Langerhans cells': '0.135', 'Erythroid cells': '-0.072', 'Adipocytes (Subcutaneous)': '-0.194', 'Adipocytes (Visceral)': '-0.106', 'Breast glandular cells (progenitors)': '0.133', 'Adipocytes (Breast)': '-0.396', 'Colon enterocytes': '0.181', 'Colon enteroendocrine cells': '0.036', 'Enteric glia cells': '0.097', 'Mitotic cells (Colon)': '0.342', 'Mitotic cells (Heart)': '0.264', 'Podocytes': '-0.149', 'Ascending Loop of Henle cells': '0.188', 'Intercalated cells': '-0.138', 'Cholangiocyte': '0.210', 'NK-cells (Liver)': '-0.261', 'Respiratory ciliated cells': '-0.159', 'Mitotic cells (Lung)': '0.251', 'NK-cells (Lung)': '-0.383', 'B-cells (Lung)': '-0.300', 'Alpha cells': '0.339', 'Beta cells': '0.136', 'Prostate glandular cells': '0.493', 'Prostate basal glandular cells': '0.392', 'Urothelial cells': '0.179', 'Keratinocyte (other)': '0.247', 'Keratinocyte (granular)': '0.624', 'Hair cortex cells': '-0.304', 'Inner root sheath cells': '-0.314', 'Outer root sheath cells': '-0.447', 'Sebaceous gland cells': '0.111', 'Eccrine sweat gland cells': '-0.420', 'Adipocytes (Skin)': '-0.159', 'Mitotic cells (Skin)': '-0.134', 'Parietal cells': '0.080', 'Chief cells': '0.330', 'Gastric mucous cells': '0.320', 'Gastric enteroendocrine cells': 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activated': '10.9', 'Memory T-reg': '8.8', 'Naive T-reg': '7.3'} | null | {'Adipose Tissue': 8.809264950166112, 'Adrenal Gland': 17.54763953488372, 'Bladder': 6.9800523809523805, 'Blood': 9.43186975242196, 'Blood Vessel': 4.216821797752809, 'Brain': 3.4900453065859196, 'Breast': 11.200418300653595, 'Cervix Uteri': 5.766473684210527, 'Colon': 3.77694351732991, 'Esophagus': 10.10880795847751, 'Fallopian Tube': 3.9268888888888887, 'Heart': 2.3147218350754937, 'Kidney': 5.262460674157303, 'Liver': 43.32687610619469, 'Lung': 24.430044982698963, 'Muscle': 1.1405036239103363, 'Nerve': 8.425048465266558, 'Ovary': 5.009766666666667, 'Pancreas': 9.007713414634146, 'Pituitary': 21.826416961130743, 'Prostate': 11.24681224489796, 'Salivary Gland': 12.413938271604938, 'Skin': 30.488616915422888, 'Small Intestine': 6.5698743315508015, 'Spleen': 16.02609958506224, 'Stomach': 9.364656824512537, 'Testis': 2.5564221606648196, 'Thyroid': 10.912295558958652, 'Uterus': 4.951273943661972, 'Vagina': 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potentially alpha-catenin/CTNNA1. Forms a ternary complex composed of ADAM10, CADH1 and EPHA4, | null | null | KLRG1, SPEF1, DLGAP5, AJAP1, RAPGEF2, RAB8B, PIP5K1C, PKP2, TRPV4, CTNNB1, CAV1, DDR1, TBC1D2, CTNNA1, JUP, CTNND1, PSEN1, LIMA1, CDH1, JUP, ADAM10, CADH1 , EPHA4, | null | null | null | null | Homodimer | null | 79.91949 | 0.474025 | 77.641788 | 0.46176 | 2,088 |
P12830 | Q99618 | null | degron_data | CDH1 | MGPWSRSLSALLLLLQVSSWLCQEPEPCHPGFDAESYTFTVPRRHLERGRVLGRVNFEDCTGRQRTAYFSLDTRFKVGTDGVITVKRPLRFHNPQIHFLVYAWDSTYRKFSTKVTLNTVGHHHRPPPHQASVSGIQAELLTFPNSSPGLRRQKRDWVIPPISCPENEKGPFPKNLVQIKSNKDKEGKVFYSITGQGADTPPVGVFIIERETGWLKVTEPLDRERIATYTLFSHAVSSNGNAVEDPMEILITVTDQNDNKPEFTQEVFKGSVMEGALPGTSVMEVTATDADDDVNTYNAAIAYTILSQDPELPDKNMFTINRNTGVISVVTTGLDRESFPTYTLVVQAADLQGEGLSTTATAVITVTDTNDNPPIFNPTTYKGQVPENEANVVITTLKVTDADAPNTPAWEAVYTILNDDGGQFVVTTNPVNNDGILKTAKGLDFEAKQQYILHVAVTNVVPFEVSLTTSTATVTVDVLDVNEAPIFVPPEKRVEVSEDFGVGQEITSYTAQEPDTFMEQKITYRIWRDTANWLEINPDTGAISTRAELDREDFEHVKNSTYTALIIATDNGSPVATGTGTLLLILSDVNDNAPIPEPRTIFFCERNPKPQVINIIDADLPPNTSPFTAELTHGASANWTIQYNDPTQESIILKPKMALEVGDYKINLKLMDNQNKDQVTTLEVSVCDCEGAAGVCRKAQPVEAGLQIPAILGILGGILALLILILLLLLFLRRRAVVKEPLLPPEDDTRDNVYYYDEEGGGEEDQDFDLSQLHRGLDARPEVTRNDVAPTLMSVPRYLPRPANPDEIGNFIDENLKAADTDPTAPPYDSLLVFDYEGSGSEAASLSSLNSSESDKDQDYDYLNEWGNRFKKLADMYGGGEDD | Homo sapiens | Cell junction, adherens junction, Cell membrane, Endosome, Golgi apparatus, trans-Golgi network, Cytoplasm, Cell junction, desmosome | Tissue enhanced (parathyroid) | {'Ciliated cells': '119.1', 'Basal respiratory cells': '71.1', 'Club cells': '97.3', 'Ionocytes': '81.0', 'Mucus glandular cells': '155.0', 'Serous glandular cells': '67.8', 'Gastric mucus-secreting cells': '133.2', 'Proximal enterocytes': '140.9', 'Paneth cells': '125.1', 'Distal enterocytes': '307.5', 'Intestinal goblet cells': '173.5', 'Exocrine glandular cells': '-0.605', 'Basal prostatic cells': '68.3', 'Prostatic glandular cells': '186.7', 'Breast glandular cells': '0.773', 'Breast myoepithelial cells': '0.700', 'Glandular and luminal cells': '313.0', 'Secretory cells': '82.3', 'Basal keratinocytes': '102.5', 'Suprabasal keratinocytes': '162.6', 'Basal squamous epithelial cells': '51.0', 'Squamous epithelial cells': '106.9', 'Alveolar cells type 1': '0.437', 'Alveolar cells type 2': '0.706', 'Salivary duct cells': '95.9', 'Ductal cells': '0.541', 'Hepatocytes': '0.600', 'Cholangiocytes': '129.7', 'Proximal tubular cells': '0.042', 'Distal tubular cells': '0.0', 'Collecting duct cells': '143.9', 'Mesothelial cells': '0.799', 'Sertoli cells': '0.252', 'Granulosa cells': '12.9', 'Enteroendocrine cells': '92.4', 'Pancreatic endocrine cells': '78.1', 'Leydig cells': '0.264', 'Excitatory neurons': '0.7', 'Inhibitory neurons': '1.3', 'Cone photoreceptor cells': '0.0', 'Rod photoreceptor cells': '0.0', 'Bipolar cells': '0.2', 'Horizontal cells': '0.6', 'Astrocytes': '0.6', 'Oligodendrocyte precursor cells': '0.5', 'Oligodendrocytes': '29.9', 'Microglial cells': '0.9', 'Muller glia cells': '0.1', 'Schwann cells': '0.131', 'Spermatogonia': '0.392', 'Spermatocytes': '0.193', 'Early spermatids': '-0.217', 'Late spermatids': '-0.290', 'Oocytes': '16.9', 'Cytotrophoblasts': '119.2', 'Syncytiotrophoblasts': '45.0', 'Extravillous trophoblasts': '24.9', 'Endothelial cells': '6.1', 'Lymphatic endothelial cells': '0.4', 'Cardiomyocytes': '0.135', 'Skeletal myocytes': '0.107', 'Smooth muscle cells': '5.8', 'Adipocytes': '2.1', 'Melanocytes': '0.335', 'Fibroblasts': '6.5', 'Peritubular cells': '0.210', 'Endometrial stromal cells': '27.7', 'Ovarian stromal cells': '0.7', 'Undifferentiated cells': '101.6', 'T-cells': '2.9', 'B-cells': '4.4', 'Plasma cells': '6.1', 'Nk-cells': '0.0', 'Granulocytes': '8.4', 'Monocytes': '0.0', 'Macrophages': '6.0', 'Hofbauer cells': '4.3', 'Kupffer cells': '1.0', 'Dendritic cells': '5.9', 'Langerhans cells': '0.304', 'Erythroid cells': '0.036', 'Adipocytes (Subcutaneous)': '-0.081', 'Adipocytes (Visceral)': '-0.209', 'Breast glandular cells (progenitors)': '0.538', 'Adipocytes (Breast)': '-0.689', 'Colon enterocytes': '0.790', 'Colon enteroendocrine cells': '0.112', 'Enteric glia cells': '-0.048', 'Mitotic cells (Colon)': '0.299', 'Mitotic cells (Heart)': '0.120', 'Podocytes': '-0.118', 'Ascending Loop of Henle cells': '0.475', 'Intercalated cells': '0.212', 'Cholangiocyte': '0.090', 'NK-cells (Liver)': '-0.005', 'Respiratory ciliated cells': '-0.012', 'Mitotic cells (Lung)': '0.071', 'NK-cells (Lung)': '-0.266', 'B-cells (Lung)': '-0.296', 'Alpha cells': '0.270', 'Beta cells': '0.152', 'Prostate glandular cells': '0.764', 'Prostate basal glandular cells': '0.540', 'Urothelial cells': '0.205', 'Keratinocyte (other)': '0.510', 'Keratinocyte (granular)': '0.055', 'Hair cortex cells': '0.080', 'Inner root sheath cells': '0.131', 'Outer root sheath cells': '0.175', 'Sebaceous gland cells': '0.156', 'Eccrine sweat gland cells': '-0.207', 'Adipocytes (Skin)': '-0.244', 'Mitotic cells (Skin)': '0.442', 'Parietal cells': '0.654', 'Chief cells': '0.649', 'Gastric mucous cells': '0.781', 'Gastric enteroendocrine cells': '0.590', 'Mitotic cells (Stomach)': '0.445', 'Parafollicular cells': '0.173', 'Thyroid glandular cells': '0.865', 'Mitotic cells (Thyroid)': '-0.081', 'Adrenal cortex cells': '0.051', 'Adrenal medulla cells': '0.087', 'Mitotic cells (Adrenal gland)': '0.072', 'Minor salivary glandular cells': '0.371', 'Minor salivary gland ductal cells': '-0.142', 'Minor salivary gland basal cells': '0.582', 'Mitotic cells (Minor salivary gland)': '0.567', 'Adipocytes (Minor salivary gland)': '0.050', 'Somatotropes': '0.121', 'Lactotropes': '0.322', 'Gonadotropes': '0.330', 'Corticotropes': '0.180', 'Thyrotropes': '0.496', 'Undifferentiated cells (Pituitary gland)': '-0.108', 'Mitotic cells (Spleen)': '-0.228', 'Platelets': '-0.050', 'Erythrocytes': '-0.158', 'Hematopoietic stem cells': '-0.211', 'B-cells (Spleen)': '0.266', 'NK-cells (Spleen)': '0.309', 'Amygdala excitatory': '1.0', 'Cerebellar inhibitory': '0.9', 'Cge interneuron': '0.7', 'Deep-layer corticothalamic and 6b': '1.5', 'Deep-layer intratelencephalic': '0.7', 'Deep-layer near-projecting': '0.7', 'Eccentric medium spiny neuron': '0.6', 'Hippocampal ca1-3': '1.9', 'Hippocampal ca4': '1.2', 'Hippocampal dentate gyrus': '1.1', 'Lamp5-lhx6 and chandelier': '0.5', 'Lower rhombic lip': '0.8', 'Mammillary body': '0.6', 'Medium spiny neuron': '0.7', 'Mge interneuron': '1.7', 'Midbrain-derived inhibitory': '0.7', 'Miscellaneous': '0.9', 'Splatter': '3.8', 'Thalamic excitatory': '0.5', 'Upper rhombic lip': '0.8', 'Upper-layer intratelencephalic': '0.6', 'Astrocyte': '4.4', 'Bergmann glia': '0.2', 'Central nervous system macrophage': '0.6', 'Choroid plexus epithelial cell': '52.1', 'Committed oligodendrocyte precursor': '41.5', 'Ependymal cell': '4.8', 'Oligodendrocyte': '53.1', 'Oligodendrocyte precursor cell': '2.4', 'Endothelial cell': '0.7', 'Pericyte': '0.3', 'Vascular associated smooth muscle cell': '0.0', 'Fibroblast': '17.4', 'Leukocyte': '1.1', 'Basophil': '0.0', 'Eosinophil': '0.0', 'Neutrophil': '0.0', 'Classical monocyte': '0.0', 'Non-classical monocyte': '0.0', 'Intermediate monocyte': '0.0', 'T-reg': '2.3', 'GdT-cell': '0.0', 'MAIT T-cell': '0.0', 'Memory CD4 T-cell': '0.0', 'Naive CD4 T-cell': '0.1', 'Memory CD8 T-cell': '0.2', 'Naive CD8 T-cell': '0.3', 'Memory B-cell': '0.0', 'Naive B-cell': '0.1', 'Plasmacytoid DC': '46.6', 'Myeloid DC': '8.5', 'NK-cell': '0.1', 'Total PBMC': '0.7', 'Vd2 gdTCR': '0.0', 'Memory CD4 T-cell Th1\\/Th17': '0.1', 'Memory CD4 T-cell Th17': '0.2', 'Memory CD4 T-cell Th2': '2.9', 'Non-Vd2 gdTCR': '0.1', 'Memory CD4 T-cell Th1': '0.3', 'Memory CD4 T-cell TFH': '0.5', 'Terminal effector memory CD4 T-cell': '0.0', 'Central memory CD8 T-cell': '4.8', 'Effector memory CD8 T-cell': '0.0', 'Terminal effector memory CD8 T-cell': '0.6', 'Non-switched memory B-cell': '0.0', 'Plasmablast': '3.3', 'Switched memory B-cell': '0.0', 'Exhausted memory B-cell': '0.7', 'Progenitor cell': '2.3', 'Memory T-reg': '1.3', 'Naive CD4 T-cell activated': '0.3', 'Naive CD8 T-cell activated': '0.6', 'Naive T-reg': '0.1'} | 1O6S, 2O72, 2OMT, 2OMU, 2OMV, 2OMX, 2OMY, 2OMZ, 3FF7, 3FF8, 3L6X, 3L6Y, 4ZT1, 4ZTE, 6CXY, 6OLE, 6OLF, 6OLG, 6VEL, 7STZ, 8H62 | {'Adipose Tissue': 1.2125261088039867, 'Adrenal Gland': 0.1914223992248062, 'Bladder': 39.2033519047619, 'Blood': 1.340954264800861, 'Blood Vessel': 0.3121561692883895, 'Brain': 0.8550442199091597, 'Breast': 38.54918344226579, 'Cervix Uteri': 23.539115789473684, 'Colon': 43.41292142490372, 'Esophagus': 53.97513367404844, 'Fallopian Tube': 14.900277777777776, 'Heart': 0.119140469221835, 'Kidney': 25.040449438202245, 'Liver': 26.60802654867257, 'Lung': 35.447986366782004, 'Muscle': 0.1378936151930261, 'Nerve': 17.518468982229404, 'Ovary': 3.6515122222222223, 'Pancreas': 56.89676829268293, 'Pituitary': 24.68741660777385, 'Prostate': 61.279967346938776, 'Salivary Gland': 92.01685185185184, 'Skin': 79.77571720232172, 'Small Intestine': 71.7519320855615, 'Spleen': 10.061029045643156, 'Stomach': 58.07813805013927, 'Testis': 0.8144204986149585, 'Thyroid': 135.176797856049, 'Uterus': 1.442593943661972, 'Vagina': 86.52345512820513} | CDCA3 | MGSAKSVPVTPARPPPHNKHLARVADPRSPSAGILRTPIQVESSPQPGLPAGEQLEGLKHAQDSDPRSPTLGIARTPMKTSSGDPPSPLVKQLSEVFETEDSKSNLPPEPVLPPEAPLSSELDLPLGTQLSVEEQMPPWNQTEFPSKQVFSKEEARQPTETPVASQSSDKPSRDPETPRSSGSMRNRWKPNSSKVLGRSPLTILQDDNSPGTLTLRQGKRPSPLSENVSELKEGAILGTGRLLKTGGRAWEQGQDHDKENQHFPLVES | Homo sapiens | Cytoplasm, cytosol | Tissue enhanced (lymphoid tissue, retina) | {'Ciliated cells': '1.1', 'Basal respiratory cells': '5.2', 'Club cells': '1.5', 'Ionocytes': '1.5', 'Mucus glandular cells': '0.7', 'Serous glandular cells': '4.6', 'Gastric mucus-secreting cells': '4.7', 'Proximal enterocytes': '67.7', 'Paneth cells': '2.5', 'Distal enterocytes': '3.7', 'Intestinal goblet cells': '10.6', 'Exocrine glandular cells': '-0.301', 'Basal prostatic cells': '0.3', 'Prostatic glandular cells': '0.5', 'Breast glandular cells': '0.567', 'Breast myoepithelial cells': '0.513', 'Glandular and luminal cells': '2.4', 'Secretory cells': '0.3', 'Basal keratinocytes': '6.7', 'Suprabasal keratinocytes': '2.9', 'Basal squamous epithelial cells': '2.9', 'Squamous epithelial cells': '11.5', 'Alveolar cells type 1': '-0.296', 'Alveolar cells type 2': '-0.321', 'Salivary duct cells': '1.4', 'Ductal cells': '0.347', 'Hepatocytes': '0.223', 'Cholangiocytes': '1.9', 'Proximal tubular cells': '0.071', 'Distal tubular cells': '0.0', 'Collecting duct cells': '0.0', 'Mesothelial cells': '0.298', 'Sertoli cells': '-0.391', 'Granulosa cells': '3.1', 'Enteroendocrine cells': '1.5', 'Pancreatic endocrine cells': '3.4', 'Leydig cells': '-0.491', 'Excitatory neurons': '0.5', 'Inhibitory neurons': '0.6', 'Cone photoreceptor cells': '28.9', 'Rod photoreceptor cells': '25.5', 'Bipolar cells': '16.8', 'Horizontal cells': '1.9', 'Astrocytes': '0.6', 'Oligodendrocyte precursor cells': '0.5', 'Oligodendrocytes': '0.5', 'Microglial cells': '0.9', 'Muller glia cells': '1.5', 'Schwann cells': '0.180', 'Spermatogonia': '-0.216', 'Spermatocytes': '0.315', 'Early spermatids': '0.723', 'Late spermatids': '0.468', 'Oocytes': '9.6', 'Cytotrophoblasts': '32.3', 'Syncytiotrophoblasts': '10.8', 'Extravillous trophoblasts': '80.4', 'Endothelial cells': '1.5', 'Lymphatic endothelial cells': '0.0', 'Cardiomyocytes': '0.401', 'Skeletal myocytes': '-0.027', 'Smooth muscle cells': '1.6', 'Adipocytes': '0.5', 'Melanocytes': '0.321', 'Fibroblasts': '3.6', 'Peritubular cells': '-0.324', 'Endometrial stromal cells': '1.4', 'Ovarian stromal cells': '0.4', 'Undifferentiated cells': '31.6', 'T-cells': '2.9', 'B-cells': '0.9', 'Plasma cells': '20.7', 'Nk-cells': '0.9', 'Granulocytes': '0.0', 'Monocytes': '0.0', 'Macrophages': '2.8', 'Hofbauer cells': '15.3', 'Kupffer cells': '2.4', 'Dendritic cells': '0.0', 'Langerhans cells': '0.167', 'Erythroid cells': '0.095', 'Adipocytes (Subcutaneous)': '-0.417', 'Adipocytes (Visceral)': '-0.398', 'Breast glandular cells (progenitors)': '0.440', 'Adipocytes (Breast)': '-0.525', 'Colon enterocytes': '-0.009', 'Colon enteroendocrine cells': '0.020', 'Enteric glia cells': '0.421', 'Mitotic cells (Colon)': '0.107', 'Mitotic cells (Heart)': '0.407', 'Podocytes': '-0.213', 'Ascending Loop of Henle cells': '0.436', 'Intercalated cells': '-0.126', 'Cholangiocyte': '0.223', 'NK-cells (Liver)': '0.012', 'Respiratory ciliated cells': '0.132', 'Mitotic cells (Lung)': '0.575', 'NK-cells (Lung)': '0.073', 'B-cells (Lung)': '0.182', 'Alpha cells': '0.315', 'Beta cells': '0.159', 'Prostate glandular cells': '-0.209', 'Prostate basal glandular cells': '0.064', 'Urothelial cells': '0.152', 'Keratinocyte (other)': '0.114', 'Keratinocyte (granular)': '-0.254', 'Hair cortex cells': '0.099', 'Inner root sheath cells': '0.194', 'Outer root sheath cells': '0.326', 'Sebaceous gland cells': '0.068', 'Eccrine sweat gland cells': '-0.019', 'Adipocytes (Skin)': '-0.109', 'Mitotic cells (Skin)': '0.729', 'Parietal cells': '-0.353', 'Chief cells': '-0.256', 'Gastric mucous cells': '0.134', 'Gastric enteroendocrine cells': '-0.048', 'Mitotic cells (Stomach)': '0.598', 'Parafollicular cells': '0.027', 'Thyroid glandular cells': '-0.096', 'Mitotic cells (Thyroid)': '0.184', 'Adrenal cortex cells': '0.131', 'Adrenal medulla cells': '0.159', 'Mitotic cells (Adrenal gland)': '0.397', 'Minor salivary glandular cells': '0.060', 'Minor salivary gland ductal cells': '-0.112', 'Minor salivary gland basal cells': '0.353', 'Mitotic cells (Minor salivary gland)': '0.486', 'Adipocytes (Minor salivary gland)': '-0.002', 'Somatotropes': '0.221', 'Lactotropes': '0.336', 'Gonadotropes': '0.147', 'Corticotropes': '0.148', 'Thyrotropes': '0.192', 'Undifferentiated cells (Pituitary gland)': '-0.215', 'Mitotic cells (Spleen)': '0.880', 'Platelets': '0.049', 'Erythrocytes': '0.381', 'Hematopoietic stem cells': '0.281', 'B-cells (Spleen)': '-0.107', 'NK-cells (Spleen)': '-0.166', 'Amygdala excitatory': '0.6', 'Cerebellar inhibitory': '1.5', 'Cge interneuron': '0.9', 'Deep-layer corticothalamic and 6b': '0.7', 'Deep-layer intratelencephalic': '0.9', 'Deep-layer near-projecting': '1.1', 'Eccentric medium spiny neuron': '0.8', 'Hippocampal ca1-3': '0.8', 'Hippocampal ca4': '0.5', 'Hippocampal dentate gyrus': '0.8', 'Lamp5-lhx6 and chandelier': '1.2', 'Lower rhombic lip': '1.1', 'Mammillary body': '1.2', 'Medium spiny neuron': '1.0', 'Mge interneuron': '1.0', 'Midbrain-derived inhibitory': '1.1', 'Miscellaneous': '0.6', 'Splatter': '0.9', 'Thalamic excitatory': '1.2', 'Upper rhombic lip': '1.5', 'Upper-layer intratelencephalic': '1.2', 'Astrocyte': '1.1', 'Bergmann glia': '1.3', 'Central nervous system macrophage': '0.4', 'Choroid plexus epithelial cell': '0.2', 'Committed oligodendrocyte precursor': '1.1', 'Ependymal cell': '0.6', 'Oligodendrocyte': '0.7', 'Oligodendrocyte precursor cell': '0.9', 'Endothelial cell': '0.1', 'Pericyte': '0.7', 'Vascular associated smooth muscle cell': '2.2', 'Fibroblast': '0.3', 'Leukocyte': '0.6', 'Basophil': '0.5', 'Eosinophil': '0.0', 'Neutrophil': '0.0', 'Classical monocyte': '0.4', 'Non-classical monocyte': '0.4', 'Intermediate monocyte': '0.8', 'T-reg': '1.6', 'GdT-cell': '0.1', 'MAIT T-cell': '1.1', 'Memory CD4 T-cell': '0.7', 'Naive CD4 T-cell': '1.4', 'Memory CD8 T-cell': '0.8', 'Naive CD8 T-cell': '1.5', 'Memory B-cell': '0.7', 'Naive B-cell': '0.5', 'Plasmacytoid DC': '5.0', 'Myeloid DC': '1.2', 'NK-cell': '1.3', 'Total PBMC': '1.9', 'Vd2 gdTCR': '0.4', 'Memory CD4 T-cell Th1\\/Th17': '0.9', 'Memory CD4 T-cell Th17': '0.7', 'Memory CD4 T-cell Th2': '0.8', 'Non-Vd2 gdTCR': '0.6', 'Memory CD4 T-cell Th1': '1.2', 'Memory CD4 T-cell TFH': '0.8', 'Terminal effector memory CD4 T-cell': '0.6', 'Central memory CD8 T-cell': '1.6', 'Effector memory CD8 T-cell': '3.1', 'Terminal effector memory CD8 T-cell': '0.9', 'Non-switched memory B-cell': '1.3', 'Plasmablast': '17.1', 'Switched memory B-cell': '2.1', 'Exhausted memory B-cell': '1.8', 'Progenitor cell': '0.6', 'Memory T-reg': '1.5', 'Naive CD4 T-cell activated': '0.6', 'Naive CD8 T-cell activated': '0.7', 'Naive T-reg': '1.6'} | null | {'Adipose Tissue': 1.697385880398671, 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48.76, 44.51, 52.23, 46.62, 48.92, 43.87, 49.74, 42.75, 50.43, 42.95, 52.65, 44.64, 41.15, 45.26, 44.3, 61.81, 40.8, 44.45, 50.89, 38.46, 46.09, 49.81, 44.21, 48.05, 46.93, 50.99, 48.8, 44.97, 48.25, 59.49, 52.02, 56.72, 42.77, 46.09, 46.18, 40.11, 45.39, 41.14, 48.11, 47.55, 52.59, 55.94, 48.67, 46.45, 55.02, 48.48, 51.64, 56.82, 55.28, 50.28, 56.05, 48.96, 46.3, 51.74, 56.19, 53.76, 55.49, 46.51, 46.04, 46.64, 46.17, 56.17, 55.94, 46.02, 55.17, 47.29, 52.63, 59.28, 56.66, 52.2, 49.55, 43.55, 54.42, 55.0, 60.58, 65.81, 71.48, 74.3, 75.11, 74.08, 67.23, 66.18, 71.01, 68.39, 67.31, 68.67, 68.7, 58.64, 59.04, 56.02, 52.65, 54.78, 57.51, 57.97, 56.9, 60.17, 56.23, 58.43, 59.56, 61.17, 57.68, 59.59, 62.55, 65.77, 67.76, 49.25, 62.01, 60.43, 48.29, 57.24, 57.12, 51.72, 46.87, 40.78, 54.92, 53.4, 49.96, 48.06, 44.03, 51.2, 46.16, 58.1, 47.96, 53.82, 38.75, 38.07, 48.9, 41.41, 51.94, 49.36, 43.24, 48.37, 48.91, 57.04, 58.66, 60.69, 71.4, 71.04, 61.9, 64.67, 65.82, 64.2, 70.36, 68.57, 62.2, 60.72, 52.16] | [1.0, 1.0, 0.89, 0.95, 0.91, 0.88, 0.82, 0.84, 0.86, 0.84, 0.86, 0.87, 0.94, 0.91, 0.87, 0.92, 0.75, 0.46, 0.77, 0.77, 0.61, 0.63, 0.9, 0.61, 0.84, 0.49, 0.89, 0.91, 0.52, 0.85, 0.48, 0.93, 0.88, 0.54, 0.94, 0.69, 0.88, 0.89, 0.8, 0.84, 0.64, 0.88, 0.83, 0.82, 0.9, 0.88, 0.89, 0.88, 0.92, 0.97, 0.98, 0.94, 0.99, 0.99, 0.99, 0.98, 1.0, 0.94, 1.0, 0.73, 0.98, 0.77, 0.87, 0.91, 0.5, 0.89, 0.91, 0.51, 0.86, 0.62, 0.9, 0.92, 0.64, 0.9, 0.89, 0.93, 0.89, 0.89, 0.96, 0.77, 0.73, 0.84, 0.92, 0.79, 0.92, 0.55, 0.48, 0.75, 0.64, 0.45, 0.57, 0.63, 0.45, 0.38, 0.64, 0.62, 0.63, 0.62, 0.7, 0.8, 0.76, 0.73, 0.84, 0.66, 0.89, 0.87, 0.92, 0.91, 0.87, 0.84, 0.9, 0.94, 0.93, 0.92, 0.99, 0.91, 0.87, 0.99, 0.82, 0.98, 0.98, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 0.98, 1.0, 0.98, 0.99, 1.0, 0.88, 0.99, 0.85, 0.98, 0.95, 0.87, 0.96, 0.89, 1.0, 0.92, 0.99, 0.98, 0.98, 0.96, 0.98, 0.85, 0.92, 0.86, 0.93, 0.91, 0.97, 0.87, 0.99, 0.97, 0.99, 0.99, 0.92, 1.0, 0.98, 1.0, 1.0, 0.99, 1.0, 0.99, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 0.99, 0.98, 0.98, 0.95, 0.96, 0.95, 0.98, 0.99, 0.93, 0.94, 0.92, 0.94, 0.85, 0.94, 0.8, 0.89, 0.99, 0.9, 0.99, 0.91, 0.93, 0.67, 0.52, 0.75, 0.7, 0.34, 0.52, 0.67, 0.71, 0.43, 0.77, 0.75, 0.68, 0.96, 0.83, 0.86, 0.96, 0.69, 0.87, 0.88, 0.91, 0.91, 0.96, 0.97, 0.9, 0.88, 0.9, 0.95, 0.79, 0.87, 0.91, 0.81, 0.94, 0.97, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 0.96, 1.0, 0.96, 0.95, 0.9, 0.87, 0.92, 0.89, 0.99, 1.0, 0.9, 0.98, 0.89, 0.96, 0.95, 0.76, 0.72, 0.9, 0.6, 0.72, 0.77, 0.86, 0.78, 0.86, 0.85, 0.93, 0.92, 0.77, 0.92, 0.81, 0.98] | null | Component of an E-cadherin/ catenin adhesion complex composed of at least E-cadherin/CDH1, beta-catenin/CTNNB1 or gamma-catenin/JUP, and potentially alpha-catenin/CTNNA1. Forms a ternary complex composed of ADAM10, CADH1 and EPHA4, | null | null | KLRG1, SPEF1, DLGAP5, AJAP1, RAPGEF2, RAB8B, PIP5K1C, PKP2, TRPV4, CTNNB1, CAV1, DDR1, TBC1D2, CTNNA1, JUP, CTNND1, PSEN1, LIMA1, CDH1, JUP, ADAM10, CADH1 , EPHA4, | null | null | null | null | Homodimer | null | 79.91949 | 0.474025 | 59.097799 | 0.865634 | 2,497 |
P12830 | Q99728 | null | degron_data | CDH1 | MGPWSRSLSALLLLLQVSSWLCQEPEPCHPGFDAESYTFTVPRRHLERGRVLGRVNFEDCTGRQRTAYFSLDTRFKVGTDGVITVKRPLRFHNPQIHFLVYAWDSTYRKFSTKVTLNTVGHHHRPPPHQASVSGIQAELLTFPNSSPGLRRQKRDWVIPPISCPENEKGPFPKNLVQIKSNKDKEGKVFYSITGQGADTPPVGVFIIERETGWLKVTEPLDRERIATYTLFSHAVSSNGNAVEDPMEILITVTDQNDNKPEFTQEVFKGSVMEGALPGTSVMEVTATDADDDVNTYNAAIAYTILSQDPELPDKNMFTINRNTGVISVVTTGLDRESFPTYTLVVQAADLQGEGLSTTATAVITVTDTNDNPPIFNPTTYKGQVPENEANVVITTLKVTDADAPNTPAWEAVYTILNDDGGQFVVTTNPVNNDGILKTAKGLDFEAKQQYILHVAVTNVVPFEVSLTTSTATVTVDVLDVNEAPIFVPPEKRVEVSEDFGVGQEITSYTAQEPDTFMEQKITYRIWRDTANWLEINPDTGAISTRAELDREDFEHVKNSTYTALIIATDNGSPVATGTGTLLLILSDVNDNAPIPEPRTIFFCERNPKPQVINIIDADLPPNTSPFTAELTHGASANWTIQYNDPTQESIILKPKMALEVGDYKINLKLMDNQNKDQVTTLEVSVCDCEGAAGVCRKAQPVEAGLQIPAILGILGGILALLILILLLLLFLRRRAVVKEPLLPPEDDTRDNVYYYDEEGGGEEDQDFDLSQLHRGLDARPEVTRNDVAPTLMSVPRYLPRPANPDEIGNFIDENLKAADTDPTAPPYDSLLVFDYEGSGSEAASLSSLNSSESDKDQDYDYLNEWGNRFKKLADMYGGGEDD | Homo sapiens | Cell junction, adherens junction, Cell membrane, Endosome, Golgi apparatus, trans-Golgi network, Cytoplasm, Cell junction, desmosome | Tissue enhanced (parathyroid) | {'Ciliated cells': '119.1', 'Basal respiratory cells': '71.1', 'Club cells': '97.3', 'Ionocytes': '81.0', 'Mucus glandular cells': '155.0', 'Serous glandular cells': '67.8', 'Gastric mucus-secreting cells': '133.2', 'Proximal enterocytes': '140.9', 'Paneth cells': '125.1', 'Distal enterocytes': '307.5', 'Intestinal goblet cells': '173.5', 'Exocrine glandular cells': '-0.605', 'Basal prostatic cells': '68.3', 'Prostatic glandular cells': '186.7', 'Breast glandular cells': '0.773', 'Breast myoepithelial cells': '0.700', 'Glandular and luminal cells': '313.0', 'Secretory cells': '82.3', 'Basal keratinocytes': '102.5', 'Suprabasal keratinocytes': '162.6', 'Basal squamous epithelial cells': '51.0', 'Squamous epithelial cells': '106.9', 'Alveolar cells type 1': '0.437', 'Alveolar cells type 2': '0.706', 'Salivary duct cells': '95.9', 'Ductal cells': '0.541', 'Hepatocytes': '0.600', 'Cholangiocytes': '129.7', 'Proximal tubular cells': '0.042', 'Distal tubular cells': '0.0', 'Collecting duct cells': '143.9', 'Mesothelial cells': '0.799', 'Sertoli cells': '0.252', 'Granulosa cells': '12.9', 'Enteroendocrine cells': '92.4', 'Pancreatic endocrine cells': '78.1', 'Leydig cells': '0.264', 'Excitatory neurons': '0.7', 'Inhibitory neurons': '1.3', 'Cone photoreceptor cells': '0.0', 'Rod photoreceptor cells': '0.0', 'Bipolar cells': '0.2', 'Horizontal cells': '0.6', 'Astrocytes': '0.6', 'Oligodendrocyte precursor cells': '0.5', 'Oligodendrocytes': '29.9', 'Microglial cells': '0.9', 'Muller glia cells': '0.1', 'Schwann cells': '0.131', 'Spermatogonia': '0.392', 'Spermatocytes': '0.193', 'Early spermatids': '-0.217', 'Late spermatids': '-0.290', 'Oocytes': '16.9', 'Cytotrophoblasts': '119.2', 'Syncytiotrophoblasts': '45.0', 'Extravillous trophoblasts': '24.9', 'Endothelial cells': '6.1', 'Lymphatic endothelial cells': '0.4', 'Cardiomyocytes': '0.135', 'Skeletal myocytes': '0.107', 'Smooth muscle cells': '5.8', 'Adipocytes': '2.1', 'Melanocytes': '0.335', 'Fibroblasts': '6.5', 'Peritubular cells': '0.210', 'Endometrial stromal cells': '27.7', 'Ovarian stromal cells': '0.7', 'Undifferentiated cells': '101.6', 'T-cells': '2.9', 'B-cells': '4.4', 'Plasma cells': '6.1', 'Nk-cells': '0.0', 'Granulocytes': '8.4', 'Monocytes': '0.0', 'Macrophages': '6.0', 'Hofbauer cells': '4.3', 'Kupffer cells': '1.0', 'Dendritic cells': '5.9', 'Langerhans cells': '0.304', 'Erythroid cells': '0.036', 'Adipocytes (Subcutaneous)': '-0.081', 'Adipocytes (Visceral)': '-0.209', 'Breast glandular cells (progenitors)': '0.538', 'Adipocytes (Breast)': '-0.689', 'Colon enterocytes': '0.790', 'Colon enteroendocrine cells': '0.112', 'Enteric glia cells': '-0.048', 'Mitotic cells (Colon)': '0.299', 'Mitotic cells (Heart)': '0.120', 'Podocytes': '-0.118', 'Ascending Loop of Henle cells': '0.475', 'Intercalated cells': '0.212', 'Cholangiocyte': '0.090', 'NK-cells (Liver)': '-0.005', 'Respiratory ciliated cells': '-0.012', 'Mitotic cells (Lung)': '0.071', 'NK-cells (Lung)': '-0.266', 'B-cells (Lung)': '-0.296', 'Alpha cells': '0.270', 'Beta cells': '0.152', 'Prostate glandular cells': '0.764', 'Prostate basal glandular cells': '0.540', 'Urothelial cells': '0.205', 'Keratinocyte (other)': '0.510', 'Keratinocyte (granular)': '0.055', 'Hair cortex cells': '0.080', 'Inner root sheath cells': '0.131', 'Outer root sheath cells': '0.175', 'Sebaceous gland cells': '0.156', 'Eccrine sweat gland cells': '-0.207', 'Adipocytes (Skin)': '-0.244', 'Mitotic cells (Skin)': '0.442', 'Parietal cells': '0.654', 'Chief cells': '0.649', 'Gastric mucous cells': '0.781', 'Gastric enteroendocrine cells': '0.590', 'Mitotic cells (Stomach)': '0.445', 'Parafollicular cells': '0.173', 'Thyroid glandular cells': '0.865', 'Mitotic cells (Thyroid)': '-0.081', 'Adrenal cortex cells': '0.051', 'Adrenal medulla cells': '0.087', 'Mitotic cells (Adrenal gland)': '0.072', 'Minor salivary glandular cells': '0.371', 'Minor salivary gland ductal cells': '-0.142', 'Minor salivary gland basal cells': '0.582', 'Mitotic cells (Minor salivary gland)': '0.567', 'Adipocytes (Minor salivary gland)': '0.050', 'Somatotropes': '0.121', 'Lactotropes': '0.322', 'Gonadotropes': '0.330', 'Corticotropes': '0.180', 'Thyrotropes': '0.496', 'Undifferentiated cells (Pituitary gland)': '-0.108', 'Mitotic cells (Spleen)': '-0.228', 'Platelets': '-0.050', 'Erythrocytes': '-0.158', 'Hematopoietic stem cells': '-0.211', 'B-cells (Spleen)': '0.266', 'NK-cells (Spleen)': '0.309', 'Amygdala excitatory': '1.0', 'Cerebellar inhibitory': '0.9', 'Cge interneuron': '0.7', 'Deep-layer corticothalamic and 6b': '1.5', 'Deep-layer intratelencephalic': '0.7', 'Deep-layer near-projecting': '0.7', 'Eccentric medium spiny neuron': '0.6', 'Hippocampal ca1-3': '1.9', 'Hippocampal ca4': '1.2', 'Hippocampal dentate gyrus': '1.1', 'Lamp5-lhx6 and chandelier': '0.5', 'Lower rhombic lip': '0.8', 'Mammillary body': '0.6', 'Medium spiny neuron': '0.7', 'Mge interneuron': '1.7', 'Midbrain-derived inhibitory': '0.7', 'Miscellaneous': '0.9', 'Splatter': '3.8', 'Thalamic excitatory': '0.5', 'Upper rhombic lip': '0.8', 'Upper-layer intratelencephalic': '0.6', 'Astrocyte': '4.4', 'Bergmann glia': '0.2', 'Central nervous system macrophage': '0.6', 'Choroid plexus epithelial cell': '52.1', 'Committed oligodendrocyte precursor': '41.5', 'Ependymal cell': '4.8', 'Oligodendrocyte': '53.1', 'Oligodendrocyte precursor cell': '2.4', 'Endothelial cell': '0.7', 'Pericyte': '0.3', 'Vascular associated smooth muscle cell': '0.0', 'Fibroblast': '17.4', 'Leukocyte': '1.1', 'Basophil': '0.0', 'Eosinophil': '0.0', 'Neutrophil': '0.0', 'Classical monocyte': '0.0', 'Non-classical monocyte': '0.0', 'Intermediate monocyte': '0.0', 'T-reg': '2.3', 'GdT-cell': '0.0', 'MAIT T-cell': '0.0', 'Memory CD4 T-cell': '0.0', 'Naive CD4 T-cell': '0.1', 'Memory CD8 T-cell': '0.2', 'Naive CD8 T-cell': '0.3', 'Memory B-cell': '0.0', 'Naive B-cell': '0.1', 'Plasmacytoid DC': '46.6', 'Myeloid DC': '8.5', 'NK-cell': '0.1', 'Total PBMC': '0.7', 'Vd2 gdTCR': '0.0', 'Memory CD4 T-cell Th1\\/Th17': '0.1', 'Memory CD4 T-cell Th17': '0.2', 'Memory CD4 T-cell Th2': '2.9', 'Non-Vd2 gdTCR': '0.1', 'Memory CD4 T-cell Th1': '0.3', 'Memory CD4 T-cell TFH': '0.5', 'Terminal effector memory CD4 T-cell': '0.0', 'Central memory CD8 T-cell': '4.8', 'Effector memory CD8 T-cell': '0.0', 'Terminal effector memory CD8 T-cell': '0.6', 'Non-switched memory B-cell': '0.0', 'Plasmablast': '3.3', 'Switched memory B-cell': '0.0', 'Exhausted memory B-cell': '0.7', 'Progenitor cell': '2.3', 'Memory T-reg': '1.3', 'Naive CD4 T-cell activated': '0.3', 'Naive CD8 T-cell activated': '0.6', 'Naive T-reg': '0.1'} | 1O6S, 2O72, 2OMT, 2OMU, 2OMV, 2OMX, 2OMY, 2OMZ, 3FF7, 3FF8, 3L6X, 3L6Y, 4ZT1, 4ZTE, 6CXY, 6OLE, 6OLF, 6OLG, 6VEL, 7STZ, 8H62 | {'Adipose Tissue': 1.2125261088039867, 'Adrenal Gland': 0.1914223992248062, 'Bladder': 39.2033519047619, 'Blood': 1.340954264800861, 'Blood Vessel': 0.3121561692883895, 'Brain': 0.8550442199091597, 'Breast': 38.54918344226579, 'Cervix Uteri': 23.539115789473684, 'Colon': 43.41292142490372, 'Esophagus': 53.97513367404844, 'Fallopian Tube': 14.900277777777776, 'Heart': 0.119140469221835, 'Kidney': 25.040449438202245, 'Liver': 26.60802654867257, 'Lung': 35.447986366782004, 'Muscle': 0.1378936151930261, 'Nerve': 17.518468982229404, 'Ovary': 3.6515122222222223, 'Pancreas': 56.89676829268293, 'Pituitary': 24.68741660777385, 'Prostate': 61.279967346938776, 'Salivary Gland': 92.01685185185184, 'Skin': 79.77571720232172, 'Small Intestine': 71.7519320855615, 'Spleen': 10.061029045643156, 'Stomach': 58.07813805013927, 'Testis': 0.8144204986149585, 'Thyroid': 135.176797856049, 'Uterus': 1.442593943661972, 'Vagina': 86.52345512820513} | BARD1 | MPDNRQPRNRQPRIRSGNEPRSAPAMEPDGRGAWAHSRAALDRLEKLLRCSRCTNILREPVCLGGCEHIFCSNCVSDCIGTGCPVCYTPAWIQDLKINRQLDSMIQLCSKLRNLLHDNELSDLKEDKPRKSLFNDAGNKKNSIKMWFSPRSKKVRYVVSKASVQTQPAIKKDASAQQDSYEFVSPSPPADVSERAKKASARSGKKQKKKTLAEINQKWNLEAEKEDGEFDSKEESKQKLVSFCSQPSVISSPQINGEIDLLASGSLTESECFGSLTEVSLPLAEQIESPDTKSRNEVVTPEKVCKNYLTSKKSLPLENNGKRGHHNRLSSPISKRCRTSILSTSGDFVKQTVPSENIPLPECSSPPSCKRKVGGTSGRKNSNMSDEFISLSPGTPPSTLSSSSYRRVMSSPSAMKLLPNMAVKRNHRGETLLHIASIKGDIPSVEYLLQNGSDPNVKDHAGWTPLHEACNHGHLKVVELLLQHKALVNTTGYQNDSPLHDAAKNGHVDIVKLLLSYGASRNAVNIFGLRPVDYTDDESMKSLLLLPEKNESSSASHCSVMNTGQRRDGPLVLIGSGLSSEQQKMLSELAVILKAKKYTEFDSTVTHVVVPGDAVQSTLKCMLGILNGCWILKFEWVKACLRRKVCEQEEKYEIPEGPRRSRLNREQLLPKLFDGCYFYLWGTFKHHPKDNLIKLVTAGGGQILSRKPKPDSDVTQTINTVAYHARPDSDQRFCTQYIIYEDLCNYHPERVRQGKVWKAPSSWFIDCVMSFELLPLDS | Homo sapiens | Nucleus | Low tissue specificity | {'Ciliated cells': '12.1', 'Basal respiratory cells': '12.3', 'Club cells': '17.4', 'Ionocytes': '14.0', 'Mucus glandular cells': '6.6', 'Serous glandular cells': '14.1', 'Gastric mucus-secreting cells': '9.4', 'Proximal enterocytes': '2.3', 'Paneth cells': '8.8', 'Distal enterocytes': '7.0', 'Intestinal goblet cells': '12.3', 'Exocrine glandular cells': '-0.572', 'Basal prostatic cells': '11.7', 'Prostatic glandular cells': '4.6', 'Breast glandular cells': '0.534', 'Breast myoepithelial cells': '0.671', 'Glandular and luminal cells': '17.1', 'Secretory cells': '20.8', 'Basal keratinocytes': '58.7', 'Suprabasal keratinocytes': '56.9', 'Basal squamous epithelial cells': '17.7', 'Squamous epithelial cells': '27.4', 'Alveolar cells type 1': '0.042', 'Alveolar cells type 2': '-0.188', 'Salivary duct cells': '13.1', 'Ductal cells': '0.690', 'Hepatocytes': '0.301', 'Cholangiocytes': '11.4', 'Proximal tubular cells': '-0.015', 'Distal tubular cells': '3.1', 'Collecting duct cells': '7.8', 'Mesothelial cells': '0.141', 'Sertoli cells': '0.284', 'Granulosa cells': '18.9', 'Enteroendocrine cells': '6.2', 'Pancreatic endocrine cells': '0.0', 'Leydig cells': '0.294', 'Excitatory neurons': '5.3', 'Inhibitory neurons': '14.8', 'Cone photoreceptor cells': '1.7', 'Rod photoreceptor cells': '6.8', 'Bipolar cells': '3.5', 'Horizontal cells': '4.4', 'Astrocytes': '13.9', 'Oligodendrocyte precursor cells': '18.4', 'Oligodendrocytes': '29.5', 'Microglial cells': '15.2', 'Muller glia cells': '3.7', 'Schwann cells': '0.180', 'Spermatogonia': '0.610', 'Spermatocytes': '0.647', 'Early spermatids': '0.148', 'Late spermatids': '-0.387', 'Oocytes': '43.4', 'Cytotrophoblasts': '19.4', 'Syncytiotrophoblasts': '6.1', 'Extravillous trophoblasts': '16.8', 'Endothelial cells': '12.0', 'Lymphatic endothelial cells': '10.0', 'Cardiomyocytes': '0.460', 'Skeletal myocytes': '0.225', 'Smooth muscle cells': '16.8', 'Adipocytes': '12.9', 'Melanocytes': '0.173', 'Fibroblasts': '8.3', 'Peritubular cells': '0.242', 'Endometrial stromal cells': '10.9', 'Ovarian stromal cells': '9.1', 'Undifferentiated cells': '24.9', 'T-cells': '14.4', 'B-cells': '14.2', 'Plasma cells': 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Forms a ternary complex composed of ADAM10, CADH1 and EPHA4, | null | null | KLRG1, SPEF1, DLGAP5, AJAP1, RAPGEF2, RAB8B, PIP5K1C, PKP2, TRPV4, CTNNB1, CAV1, DDR1, TBC1D2, CTNNA1, JUP, CTNND1, PSEN1, LIMA1, CDH1, JUP, ADAM10, CADH1 , EPHA4, | null | null | null | null | Homodimer | null | 79.91949 | 0.474025 | 65.133642 | 0.582561 | 847 |
P12830 | Q99741 | null | degron_data | CDH1 | MGPWSRSLSALLLLLQVSSWLCQEPEPCHPGFDAESYTFTVPRRHLERGRVLGRVNFEDCTGRQRTAYFSLDTRFKVGTDGVITVKRPLRFHNPQIHFLVYAWDSTYRKFSTKVTLNTVGHHHRPPPHQASVSGIQAELLTFPNSSPGLRRQKRDWVIPPISCPENEKGPFPKNLVQIKSNKDKEGKVFYSITGQGADTPPVGVFIIERETGWLKVTEPLDRERIATYTLFSHAVSSNGNAVEDPMEILITVTDQNDNKPEFTQEVFKGSVMEGALPGTSVMEVTATDADDDVNTYNAAIAYTILSQDPELPDKNMFTINRNTGVISVVTTGLDRESFPTYTLVVQAADLQGEGLSTTATAVITVTDTNDNPPIFNPTTYKGQVPENEANVVITTLKVTDADAPNTPAWEAVYTILNDDGGQFVVTTNPVNNDGILKTAKGLDFEAKQQYILHVAVTNVVPFEVSLTTSTATVTVDVLDVNEAPIFVPPEKRVEVSEDFGVGQEITSYTAQEPDTFMEQKITYRIWRDTANWLEINPDTGAISTRAELDREDFEHVKNSTYTALIIATDNGSPVATGTGTLLLILSDVNDNAPIPEPRTIFFCERNPKPQVINIIDADLPPNTSPFTAELTHGASANWTIQYNDPTQESIILKPKMALEVGDYKINLKLMDNQNKDQVTTLEVSVCDCEGAAGVCRKAQPVEAGLQIPAILGILGGILALLILILLLLLFLRRRAVVKEPLLPPEDDTRDNVYYYDEEGGGEEDQDFDLSQLHRGLDARPEVTRNDVAPTLMSVPRYLPRPANPDEIGNFIDENLKAADTDPTAPPYDSLLVFDYEGSGSEAASLSSLNSSESDKDQDYDYLNEWGNRFKKLADMYGGGEDD | Homo sapiens | Cell junction, adherens junction, Cell membrane, Endosome, Golgi apparatus, trans-Golgi network, Cytoplasm, Cell junction, desmosome | Tissue enhanced (parathyroid) | {'Ciliated cells': '119.1', 'Basal respiratory cells': '71.1', 'Club cells': '97.3', 'Ionocytes': '81.0', 'Mucus glandular cells': '155.0', 'Serous glandular cells': '67.8', 'Gastric mucus-secreting cells': '133.2', 'Proximal enterocytes': '140.9', 'Paneth cells': '125.1', 'Distal enterocytes': '307.5', 'Intestinal goblet cells': '173.5', 'Exocrine glandular cells': '-0.605', 'Basal prostatic cells': '68.3', 'Prostatic glandular cells': '186.7', 'Breast glandular cells': '0.773', 'Breast myoepithelial cells': '0.700', 'Glandular and luminal cells': '313.0', 'Secretory cells': '82.3', 'Basal keratinocytes': '102.5', 'Suprabasal keratinocytes': '162.6', 'Basal squamous epithelial cells': '51.0', 'Squamous epithelial cells': '106.9', 'Alveolar cells type 1': '0.437', 'Alveolar cells type 2': '0.706', 'Salivary duct cells': '95.9', 'Ductal cells': '0.541', 'Hepatocytes': '0.600', 'Cholangiocytes': '129.7', 'Proximal tubular cells': '0.042', 'Distal tubular cells': '0.0', 'Collecting duct cells': '143.9', 'Mesothelial cells': '0.799', 'Sertoli cells': '0.252', 'Granulosa cells': '12.9', 'Enteroendocrine cells': '92.4', 'Pancreatic endocrine cells': '78.1', 'Leydig cells': '0.264', 'Excitatory neurons': '0.7', 'Inhibitory neurons': '1.3', 'Cone photoreceptor cells': '0.0', 'Rod photoreceptor cells': '0.0', 'Bipolar cells': '0.2', 'Horizontal cells': '0.6', 'Astrocytes': '0.6', 'Oligodendrocyte precursor cells': '0.5', 'Oligodendrocytes': '29.9', 'Microglial cells': '0.9', 'Muller glia cells': '0.1', 'Schwann cells': '0.131', 'Spermatogonia': '0.392', 'Spermatocytes': '0.193', 'Early spermatids': '-0.217', 'Late spermatids': '-0.290', 'Oocytes': '16.9', 'Cytotrophoblasts': '119.2', 'Syncytiotrophoblasts': '45.0', 'Extravillous trophoblasts': '24.9', 'Endothelial cells': '6.1', 'Lymphatic endothelial cells': '0.4', 'Cardiomyocytes': '0.135', 'Skeletal myocytes': '0.107', 'Smooth muscle cells': '5.8', 'Adipocytes': '2.1', 'Melanocytes': '0.335', 'Fibroblasts': '6.5', 'Peritubular cells': '0.210', 'Endometrial stromal cells': '27.7', 'Ovarian stromal cells': '0.7', 'Undifferentiated cells': '101.6', 'T-cells': '2.9', 'B-cells': '4.4', 'Plasma cells': '6.1', 'Nk-cells': '0.0', 'Granulocytes': '8.4', 'Monocytes': '0.0', 'Macrophages': '6.0', 'Hofbauer cells': '4.3', 'Kupffer cells': '1.0', 'Dendritic cells': '5.9', 'Langerhans cells': '0.304', 'Erythroid cells': '0.036', 'Adipocytes (Subcutaneous)': '-0.081', 'Adipocytes (Visceral)': '-0.209', 'Breast glandular cells (progenitors)': '0.538', 'Adipocytes (Breast)': '-0.689', 'Colon enterocytes': '0.790', 'Colon enteroendocrine cells': '0.112', 'Enteric glia cells': '-0.048', 'Mitotic cells (Colon)': '0.299', 'Mitotic cells (Heart)': '0.120', 'Podocytes': '-0.118', 'Ascending Loop of Henle cells': '0.475', 'Intercalated cells': '0.212', 'Cholangiocyte': '0.090', 'NK-cells (Liver)': '-0.005', 'Respiratory ciliated cells': '-0.012', 'Mitotic cells (Lung)': '0.071', 'NK-cells (Lung)': '-0.266', 'B-cells (Lung)': '-0.296', 'Alpha cells': '0.270', 'Beta cells': '0.152', 'Prostate glandular cells': '0.764', 'Prostate basal glandular cells': '0.540', 'Urothelial cells': '0.205', 'Keratinocyte (other)': '0.510', 'Keratinocyte (granular)': '0.055', 'Hair cortex cells': '0.080', 'Inner root sheath cells': '0.131', 'Outer root sheath cells': '0.175', 'Sebaceous gland cells': '0.156', 'Eccrine sweat gland cells': '-0.207', 'Adipocytes (Skin)': '-0.244', 'Mitotic cells (Skin)': '0.442', 'Parietal cells': '0.654', 'Chief cells': '0.649', 'Gastric mucous cells': '0.781', 'Gastric enteroendocrine cells': '0.590', 'Mitotic cells (Stomach)': '0.445', 'Parafollicular cells': '0.173', 'Thyroid glandular cells': '0.865', 'Mitotic cells (Thyroid)': '-0.081', 'Adrenal cortex cells': '0.051', 'Adrenal medulla cells': '0.087', 'Mitotic cells (Adrenal gland)': '0.072', 'Minor salivary glandular cells': '0.371', 'Minor salivary gland ductal cells': '-0.142', 'Minor salivary gland basal cells': '0.582', 'Mitotic cells (Minor salivary gland)': '0.567', 'Adipocytes (Minor salivary gland)': '0.050', 'Somatotropes': '0.121', 'Lactotropes': '0.322', 'Gonadotropes': '0.330', 'Corticotropes': '0.180', 'Thyrotropes': '0.496', 'Undifferentiated cells (Pituitary gland)': '-0.108', 'Mitotic cells (Spleen)': '-0.228', 'Platelets': '-0.050', 'Erythrocytes': '-0.158', 'Hematopoietic stem cells': '-0.211', 'B-cells (Spleen)': '0.266', 'NK-cells (Spleen)': '0.309', 'Amygdala excitatory': '1.0', 'Cerebellar inhibitory': '0.9', 'Cge interneuron': '0.7', 'Deep-layer corticothalamic and 6b': '1.5', 'Deep-layer intratelencephalic': '0.7', 'Deep-layer near-projecting': '0.7', 'Eccentric medium spiny neuron': '0.6', 'Hippocampal ca1-3': '1.9', 'Hippocampal ca4': '1.2', 'Hippocampal dentate gyrus': '1.1', 'Lamp5-lhx6 and chandelier': '0.5', 'Lower rhombic lip': '0.8', 'Mammillary body': '0.6', 'Medium spiny neuron': '0.7', 'Mge interneuron': '1.7', 'Midbrain-derived inhibitory': '0.7', 'Miscellaneous': '0.9', 'Splatter': '3.8', 'Thalamic excitatory': '0.5', 'Upper rhombic lip': '0.8', 'Upper-layer intratelencephalic': '0.6', 'Astrocyte': '4.4', 'Bergmann glia': '0.2', 'Central nervous system macrophage': '0.6', 'Choroid plexus epithelial cell': '52.1', 'Committed oligodendrocyte precursor': '41.5', 'Ependymal cell': '4.8', 'Oligodendrocyte': '53.1', 'Oligodendrocyte precursor cell': '2.4', 'Endothelial cell': '0.7', 'Pericyte': '0.3', 'Vascular associated smooth muscle cell': '0.0', 'Fibroblast': '17.4', 'Leukocyte': '1.1', 'Basophil': '0.0', 'Eosinophil': '0.0', 'Neutrophil': '0.0', 'Classical monocyte': '0.0', 'Non-classical monocyte': '0.0', 'Intermediate monocyte': '0.0', 'T-reg': '2.3', 'GdT-cell': '0.0', 'MAIT T-cell': '0.0', 'Memory CD4 T-cell': '0.0', 'Naive CD4 T-cell': '0.1', 'Memory CD8 T-cell': '0.2', 'Naive CD8 T-cell': '0.3', 'Memory B-cell': '0.0', 'Naive B-cell': '0.1', 'Plasmacytoid DC': '46.6', 'Myeloid DC': '8.5', 'NK-cell': '0.1', 'Total PBMC': '0.7', 'Vd2 gdTCR': '0.0', 'Memory CD4 T-cell Th1\\/Th17': '0.1', 'Memory CD4 T-cell Th17': '0.2', 'Memory CD4 T-cell Th2': '2.9', 'Non-Vd2 gdTCR': '0.1', 'Memory CD4 T-cell Th1': '0.3', 'Memory CD4 T-cell TFH': '0.5', 'Terminal effector memory CD4 T-cell': '0.0', 'Central memory CD8 T-cell': '4.8', 'Effector memory CD8 T-cell': '0.0', 'Terminal effector memory CD8 T-cell': '0.6', 'Non-switched memory B-cell': '0.0', 'Plasmablast': '3.3', 'Switched memory B-cell': '0.0', 'Exhausted memory B-cell': '0.7', 'Progenitor cell': '2.3', 'Memory T-reg': '1.3', 'Naive CD4 T-cell activated': '0.3', 'Naive CD8 T-cell activated': '0.6', 'Naive T-reg': '0.1'} | 1O6S, 2O72, 2OMT, 2OMU, 2OMV, 2OMX, 2OMY, 2OMZ, 3FF7, 3FF8, 3L6X, 3L6Y, 4ZT1, 4ZTE, 6CXY, 6OLE, 6OLF, 6OLG, 6VEL, 7STZ, 8H62 | {'Adipose Tissue': 1.2125261088039867, 'Adrenal Gland': 0.1914223992248062, 'Bladder': 39.2033519047619, 'Blood': 1.340954264800861, 'Blood Vessel': 0.3121561692883895, 'Brain': 0.8550442199091597, 'Breast': 38.54918344226579, 'Cervix Uteri': 23.539115789473684, 'Colon': 43.41292142490372, 'Esophagus': 53.97513367404844, 'Fallopian Tube': 14.900277777777776, 'Heart': 0.119140469221835, 'Kidney': 25.040449438202245, 'Liver': 26.60802654867257, 'Lung': 35.447986366782004, 'Muscle': 0.1378936151930261, 'Nerve': 17.518468982229404, 'Ovary': 3.6515122222222223, 'Pancreas': 56.89676829268293, 'Pituitary': 24.68741660777385, 'Prostate': 61.279967346938776, 'Salivary Gland': 92.01685185185184, 'Skin': 79.77571720232172, 'Small Intestine': 71.7519320855615, 'Spleen': 10.061029045643156, 'Stomach': 58.07813805013927, 'Testis': 0.8144204986149585, 'Thyroid': 135.176797856049, 'Uterus': 1.442593943661972, 'Vagina': 86.52345512820513} | CDC6 | MPQTRSQAQATISFPKRKLSRALNKAKNSSDAKLEPTNVQTVTCSPRVKALPLSPRKRLGDDNLCNTPHLPPCSPPKQGKKENGPPHSHTLKGRRLVFDNQLTIKSPSKRELAKVHQNKILSSVRKSQEITTNSEQRCPLKKESACVRLFKQEGTCYQQAKLVLNTAVPDRLPAREREMDVIRNFLREHICGKKAGSLYLSGAPGTGKTACLSRILQDLKKELKGFKTIMLNCMSLRTAQAVFPAIAQEICQEEVSRPAGKDMMRKLEKHMTAEKGPMIVLVLDEMDQLDSKGQDVLYTLFEWPWLSNSHLVLIGIANTLDLTDRILPRLQAREKCKPQLLNFPPYTRNQIVTILQDRLNQVSRDQVLDNAAVQFCARKVSAVSGDVRKALDVCRRAIEIVESDVKSQTILKPLSECKSPSEPLIPKRVGLIHISQVISEVDGNRMTLSQEGAQDSFPLQQKILVCSLMLLIRQLKIKEVTLGKLYEAYSKVCRKQQVAAVDQSECLSLSGLLEARGILGLKRNKETRLTKVFFKIEEKEIEHALKDKALIGNILATGLP | Homo sapiens | Nucleus, Cytoplasm | Tissue enhanced (bone marrow, lymphoid tissue) | {'Ciliated cells': '0.4', 'Basal respiratory cells': '3.6', 'Club cells': '1.6', 'Ionocytes': '0.7', 'Mucus glandular cells': '1.3', 'Serous glandular cells': '0.7', 'Gastric mucus-secreting cells': '3.5', 'Proximal enterocytes': '0.5', 'Paneth cells': '1.8', 'Distal enterocytes': '3.6', 'Intestinal goblet cells': '6.2', 'Exocrine glandular cells': '-0.490', 'Basal prostatic cells': '0.7', 'Prostatic glandular cells': '0.0', 'Breast glandular cells': '0.231', 'Breast myoepithelial cells': '0.343', 'Glandular and luminal cells': '4.9', 'Secretory cells': '0.8', 'Basal keratinocytes': '5.8', 'Suprabasal keratinocytes': '2.4', 'Basal squamous epithelial cells': '4.4', 'Squamous epithelial cells': '8.6', 'Alveolar cells type 1': '-0.330', 'Alveolar cells type 2': '0.024', 'Salivary duct cells': '1.4', 'Ductal cells': '0.373', 'Hepatocytes': '0.272', 'Cholangiocytes': '0.0', 'Proximal tubular cells': '0.148', 'Distal tubular cells': '0.0', 'Collecting duct cells': '0.0', 'Mesothelial cells': '0.071', 'Sertoli cells': '0.170', 'Granulosa cells': '1.1', 'Enteroendocrine cells': '1.6', 'Pancreatic endocrine cells': '8.5', 'Leydig cells': '0.193', 'Excitatory neurons': '1.9', 'Inhibitory neurons': '0.6', 'Cone photoreceptor cells': '0.0', 'Rod photoreceptor cells': '0.3', 'Bipolar cells': '0.2', 'Horizontal cells': '0.6', 'Astrocytes': '0.6', 'Oligodendrocyte precursor cells': '0.0', 'Oligodendrocytes': '0.2', 'Microglial cells': '0.0', 'Muller glia cells': '0.5', 'Schwann cells': '-0.019', 'Spermatogonia': '0.432', 'Spermatocytes': '0.787', 'Early spermatids': '-0.067', 'Late spermatids': '-0.213', 'Oocytes': '53.7', 'Cytotrophoblasts': '25.2', 'Syncytiotrophoblasts': '18.4', 'Extravillous trophoblasts': '35.1', 'Endothelial cells': '1.6', 'Lymphatic endothelial cells': '1.1', 'Cardiomyocytes': '0.160', 'Skeletal myocytes': '-0.069', 'Smooth muscle cells': '1.8', 'Adipocytes': '1.9', 'Melanocytes': '0.441', 'Fibroblasts': '4.6', 'Peritubular cells': '0.039', 'Endometrial stromal cells': '2.4', 'Ovarian stromal cells': '1.2', 'Undifferentiated cells': '22.6', 'T-cells': '2.2', 'B-cells': '3.5', 'Plasma cells': '32.6', 'Nk-cells': '2.2', 'Granulocytes': '0.1', 'Monocytes': '0.2', 'Macrophages': '1.5', 'Hofbauer cells': '6.1', 'Kupffer cells': '1.1', 'Dendritic cells': '0.4', 'Langerhans cells': '0.193', 'Erythroid cells': '-0.127', 'Adipocytes (Subcutaneous)': '-0.364', 'Adipocytes (Visceral)': '-0.236', 'Breast glandular cells (progenitors)': '0.314', 'Adipocytes (Breast)': '-0.351', 'Colon enterocytes': '0.268', 'Colon enteroendocrine cells': '-0.009', 'Enteric glia cells': '-0.034', 'Mitotic cells (Colon)': '0.555', 'Mitotic cells (Heart)': '0.582', 'Podocytes': '-0.139', 'Ascending Loop of Henle cells': '0.218', 'Intercalated cells': '-0.153', 'Cholangiocyte': '0.258', 'NK-cells (Liver)': '-0.293', 'Respiratory ciliated cells': '-0.064', 'Mitotic cells (Lung)': '0.542', 'NK-cells (Lung)': '-0.154', 'B-cells (Lung)': '-0.043', 'Alpha cells': '0.191', 'Beta cells': '0.090', 'Prostate glandular cells': '0.072', 'Prostate basal glandular cells': '0.221', 'Urothelial cells': '0.248', 'Keratinocyte (other)': '0.219', 'Keratinocyte (granular)': '-0.260', 'Hair cortex cells': '0.240', 'Inner root sheath cells': '0.359', 'Outer root sheath cells': '0.406', 'Sebaceous gland cells': '0.171', 'Eccrine sweat gland cells': '0.051', 'Adipocytes (Skin)': '-0.140', 'Mitotic cells (Skin)': '0.766', 'Parietal cells': '-0.085', 'Chief cells': '0.049', 'Gastric mucous cells': '0.375', 'Gastric enteroendocrine cells': '0.150', 'Mitotic cells (Stomach)': '0.765', 'Parafollicular cells': '-0.057', 'Thyroid glandular cells': '-0.138', 'Mitotic cells (Thyroid)': '0.373', 'Adrenal cortex cells': '0.398', 'Adrenal medulla cells': '-0.021', 'Mitotic cells (Adrenal gland)': '0.431', 'Minor salivary glandular cells': '0.116', 'Minor salivary gland ductal cells': '-0.222', 'Minor salivary gland basal cells': '0.615', 'Mitotic cells (Minor salivary gland)': '0.784', 'Adipocytes (Minor salivary gland)': '0.160', 'Somatotropes': '-0.152', 'Lactotropes': '-0.176', 'Gonadotropes': '0.171', 'Corticotropes': '-0.194', 'Thyrotropes': '-0.146', 'Undifferentiated cells (Pituitary gland)': '0.330', 'Mitotic cells (Spleen)': '0.827', 'Platelets': '0.156', 'Erythrocytes': '0.285', 'Hematopoietic stem cells': '0.230', 'B-cells (Spleen)': '-0.206', 'NK-cells (Spleen)': '-0.219', 'Amygdala excitatory': '2.8', 'Cerebellar inhibitory': '0.6', 'Cge interneuron': '1.0', 'Deep-layer corticothalamic and 6b': '1.6', 'Deep-layer intratelencephalic': '2.9', 'Deep-layer near-projecting': '1.5', 'Eccentric medium spiny neuron': '1.2', 'Hippocampal ca1-3': '1.9', 'Hippocampal ca4': '1.5', 'Hippocampal dentate gyrus': '1.9', 'Lamp5-lhx6 and chandelier': '1.2', 'Lower rhombic lip': '1.1', 'Mammillary body': '1.2', 'Medium spiny neuron': '1.4', 'Mge interneuron': '1.1', 'Midbrain-derived inhibitory': '0.7', 'Miscellaneous': '2.4', 'Splatter': '1.3', 'Thalamic excitatory': '1.8', 'Upper rhombic lip': '1.4', 'Upper-layer intratelencephalic': '5.4', 'Astrocyte': '1.9', 'Bergmann glia': '1.0', 'Central nervous system macrophage': '0.5', 'Choroid plexus epithelial cell': '0.1', 'Committed oligodendrocyte precursor': '0.4', 'Ependymal cell': '1.1', 'Oligodendrocyte': '0.3', 'Oligodendrocyte precursor cell': '0.5', 'Endothelial cell': '0.4', 'Pericyte': '0.4', 'Vascular associated smooth muscle cell': '0.0', 'Fibroblast': '0.2', 'Leukocyte': '0.6', 'Basophil': '0.6', 'Eosinophil': '0.0', 'Neutrophil': '0.4', 'Classical monocyte': '0.2', 'Non-classical monocyte': '0.3', 'Intermediate monocyte': '1.5', 'T-reg': '4.1', 'GdT-cell': '0.8', 'MAIT T-cell': '3.0', 'Memory CD4 T-cell': '0.6', 'Naive CD4 T-cell': '0.4', 'Memory CD8 T-cell': '1.1', 'Naive CD8 T-cell': '0.4', 'Memory B-cell': '0.4', 'Naive B-cell': '0.5', 'Plasmacytoid DC': '7.4', 'Myeloid DC': '0.9', 'NK-cell': '1.9', 'Total PBMC': '5.3', 'Vd2 gdTCR': '0.2', 'Memory CD4 T-cell TFH': '0.4', 'Memory CD4 T-cell Th2': '0.8', 'Memory CD4 T-cell Th17': '0.7', 'Memory CD4 T-cell Th1\\/Th17': '0.7', 'Non-Vd2 gdTCR': '3.2', 'Memory CD4 T-cell Th1': '1.3', 'Terminal effector memory CD4 T-cell': '1.2', 'Central memory CD8 T-cell': '1.7', 'Effector memory CD8 T-cell': '8.7', 'Terminal effector memory CD8 T-cell': '1.5', 'Switched memory B-cell': '3.3', 'Plasmablast': '94.4', 'Non-switched memory B-cell': '0.6', 'Exhausted memory B-cell': '4.9', 'Progenitor cell': '4.1', 'Naive CD4 T-cell activated': '1.0', 'Naive CD8 T-cell activated': '1.2', 'Memory T-reg': '2.1', 'Naive T-reg': '0.5'} | 2CCH, 2CCI, 4I5L, 4I5N, 8HT7 | {'Adipose Tissue': 1.0135120598006646, 'Adrenal Gland': 1.476743023255814, 'Bladder': 1.1341238095238095, 'Blood': 5.327745414424112, 'Blood Vessel': 0.5764714232209738, 'Brain': 0.7258613058289175, 'Breast': 0.8094962745098039, 'Cervix Uteri': 1.461278947368421, 'Colon': 1.3525910141206676, 'Esophagus': 2.140787570934256, 'Fallopian Tube': 0.9588, 'Heart': 0.4529019512195122, 'Kidney': 0.4478088764044944, 'Liver': 1.4233409292035395, 'Lung': 2.030225605536332, 'Muscle': 0.2054580946450809, 'Nerve': 0.7501828756058159, 'Ovary': 0.9998522222222224, 'Pancreas': 0.8700864024390245, 'Pituitary': 0.6330436042402827, 'Prostate': 0.9005502857142856, 'Salivary Gland': 1.3956925925925927, 'Skin': 5.488745605306799, 'Small Intestine': 2.64122192513369, 'Spleen': 5.095452697095436, 'Stomach': 1.377367409470752, 'Testis': 10.918598337950138, 'Thyroid': 0.8930437212863707, 'Uterus': 0.754343661971831, 'Vagina': 2.244133333333333} | [39.93, 46.46, 52.9, 44.21, 41.4, 39.93, 35.91, 38.61, 36.44, 36.25, 34.86, 32.82, 32.01, 32.75, 31.69, 35.64, 36.35, 34.66, 33.32, 32.71, 35.01, 30.17, 37.05, 36.53, 48.19, 58.22, 64.94, 73.22, 78.33, 82.63, 85.79, 89.39, 87.89, 85.58, 83.93, 89.1, 89.27, 90.66, 87.86, 86.2, 82.97, 72.75, 73.3, 76.44, 82.38, 82.41, 79.49, 86.6, 76.32, 85.48, 88.69, 84.35, 87.75, 90.57, 88.72, 89.46, 87.48, 85.3, 81.72, 79.46, 77.26, 69.01, 67.1, 62.83, 67.71, 74.96, 82.95, 86.74, 86.35, 86.49, 84.6, 85.99, 85.64, 87.19, 89.23, 89.3, 90.62, 84.21, 85.42, 83.34, 84.28, 89.8, 89.78, 87.53, 87.64, 85.98, 81.31, 80.85, 78.74, 80.15, 70.67, 69.91, 72.91, 77.13, 83.26, 84.67, 90.36, 89.7, 92.74, 89.99, 92.55, 88.84, 87.15, 83.78, 78.78, 81.48, 78.75, 84.94, 88.04, 89.37, 92.07, 91.77, 92.31, 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0.38, 0.59, 0.99, 0.41, 0.14, 0.64, 0.09, 0.0, 0.14, 0.16, 0.01, 0.03, 0.48, 0.03, 0.03, 0.39, 0.32, 0.79, 0.58, 0.07, 0.19, 0.0, 0.01, 0.0, 0.0, 0.0, 0.03, 0.01, 0.32, 0.47, 0.46, 0.51, 0.03, 0.11, 0.67, 0.59, 0.03, 0.12, 0.57, 0.64, 0.09, 0.52, 0.76, 0.58, 0.86, 0.78, 0.09, 0.64, 0.1, 0.41, 0.58, 0.13, 0.5, 0.01, 0.5, 0.57, 0.05, 0.56, 0.35, 0.72, 0.25, 0.01, 0.14, 0.45, 0.1, 0.01, 0.36, 0.2, 0.14, 0.19, 0.72, 0.59, 0.3, 0.31, 0.96, 0.69, 0.54, 0.1, 0.07, 0.4, 0.43, 0.46, 0.0, 0.01, 0.34, 0.24, 0.0, 0.0, 0.51, 0.48, 0.09, 0.28, 0.79, 0.66, 0.36, 0.01, 0.1, 0.12, 0.52, 0.47, 0.0, 0.06, 0.28, 0.06, 0.01, 0.36, 0.36, 0.0, 0.0, 0.34, 0.22, 0.01, 0.05, 0.53, 0.38, 0.16, 0.49, 0.42, 0.51, 0.45, 0.78, 0.78, 0.8, 0.75, 0.94, 0.81, 0.93, 0.98, 0.94, 0.87, 1.0, 0.82, 0.94, 0.83, 0.72, 0.79, 0.41, 0.43, 0.6, 0.0, 0.28, 0.44, 0.79, 0.25, 0.0, 0.35, 0.45, 0.01, 0.1, 0.36, 0.52, 0.49, 0.58, 0.28, 0.46, 0.83, 0.24, 0.3, 0.47, 0.41, 0.72, 0.97, 0.88, 0.99, 0.95, 0.81, 0.7, 0.12, 0.47, 0.48, 0.24, 0.04, 0.12, 0.04, 0.02, 0.02, 0.02, 0.01, 0.0, 0.03, 0.04, 0.09, 0.23, 0.42, 0.5, 0.46, 0.85, 0.49, 0.8, 0.33, 0.03, 0.33, 0.0, 0.06, 0.54, 0.0, 0.25, 0.46, 0.05, 0.0, 0.14, 0.5, 0.05, 0.01, 0.75, 0.49, 0.33, 0.89, 0.26, 0.76, 0.51, 0.14, 0.63, 0.38, 0.65, 0.55, 0.0, 0.33, 0.56, 0.15, 0.0, 0.33, 0.5, 0.0, 0.28, 0.77, 0.41, 0.31, 0.04, 0.01, 0.02, 0.16, 0.47, 0.82, 0.57, 1.0, 0.62, 0.51, 0.54, 0.46, 0.05, 0.43, 0.0, 0.28, 0.2, 0.55, 0.26, 0.75, 0.41, 0.79, 0.34, 0.04, 0.34, 0.53, 0.14, 0.04, 0.56, 0.33, 0.76, 0.66, 0.36, 0.05, 0.39, 0.52, 0.04, 0.25, 0.79, 0.58, 0.28, 0.18, 0.76] | null | Component of an E-cadherin/ catenin adhesion complex composed of at least E-cadherin/CDH1, beta-catenin/CTNNB1 or gamma-catenin/JUP, and potentially alpha-catenin/CTNNA1. Forms a ternary complex composed of ADAM10, CADH1 and EPHA4, | null | null | KLRG1, SPEF1, DLGAP5, AJAP1, RAPGEF2, RAB8B, PIP5K1C, PKP2, TRPV4, CTNNB1, CAV1, DDR1, TBC1D2, CTNNA1, JUP, CTNND1, PSEN1, LIMA1, CDH1, JUP, ADAM10, CADH1 , EPHA4, | null | null | null | null | Homodimer | null | 79.91949 | 0.474025 | 69.693054 | 0.520054 | 1,384 |
P12830 | Q9BSJ6-2 | null | degron_data | CDH1 | MGPWSRSLSALLLLLQVSSWLCQEPEPCHPGFDAESYTFTVPRRHLERGRVLGRVNFEDCTGRQRTAYFSLDTRFKVGTDGVITVKRPLRFHNPQIHFLVYAWDSTYRKFSTKVTLNTVGHHHRPPPHQASVSGIQAELLTFPNSSPGLRRQKRDWVIPPISCPENEKGPFPKNLVQIKSNKDKEGKVFYSITGQGADTPPVGVFIIERETGWLKVTEPLDRERIATYTLFSHAVSSNGNAVEDPMEILITVTDQNDNKPEFTQEVFKGSVMEGALPGTSVMEVTATDADDDVNTYNAAIAYTILSQDPELPDKNMFTINRNTGVISVVTTGLDRESFPTYTLVVQAADLQGEGLSTTATAVITVTDTNDNPPIFNPTTYKGQVPENEANVVITTLKVTDADAPNTPAWEAVYTILNDDGGQFVVTTNPVNNDGILKTAKGLDFEAKQQYILHVAVTNVVPFEVSLTTSTATVTVDVLDVNEAPIFVPPEKRVEVSEDFGVGQEITSYTAQEPDTFMEQKITYRIWRDTANWLEINPDTGAISTRAELDREDFEHVKNSTYTALIIATDNGSPVATGTGTLLLILSDVNDNAPIPEPRTIFFCERNPKPQVINIIDADLPPNTSPFTAELTHGASANWTIQYNDPTQESIILKPKMALEVGDYKINLKLMDNQNKDQVTTLEVSVCDCEGAAGVCRKAQPVEAGLQIPAILGILGGILALLILILLLLLFLRRRAVVKEPLLPPEDDTRDNVYYYDEEGGGEEDQDFDLSQLHRGLDARPEVTRNDVAPTLMSVPRYLPRPANPDEIGNFIDENLKAADTDPTAPPYDSLLVFDYEGSGSEAASLSSLNSSESDKDQDYDYLNEWGNRFKKLADMYGGGEDD | Homo sapiens | Cell junction, adherens junction, Cell membrane, Endosome, Golgi apparatus, trans-Golgi network, Cytoplasm, Cell junction, desmosome | Tissue enhanced (parathyroid) | {'Ciliated cells': '119.1', 'Basal respiratory cells': '71.1', 'Club cells': '97.3', 'Ionocytes': '81.0', 'Mucus glandular cells': '155.0', 'Serous glandular cells': '67.8', 'Gastric mucus-secreting cells': '133.2', 'Proximal enterocytes': '140.9', 'Paneth cells': '125.1', 'Distal enterocytes': '307.5', 'Intestinal goblet cells': '173.5', 'Exocrine glandular cells': '-0.605', 'Basal prostatic cells': '68.3', 'Prostatic glandular cells': '186.7', 'Breast glandular cells': '0.773', 'Breast myoepithelial cells': '0.700', 'Glandular and luminal cells': '313.0', 'Secretory cells': '82.3', 'Basal keratinocytes': '102.5', 'Suprabasal keratinocytes': '162.6', 'Basal squamous epithelial cells': '51.0', 'Squamous epithelial cells': '106.9', 'Alveolar cells type 1': '0.437', 'Alveolar cells type 2': '0.706', 'Salivary duct cells': '95.9', 'Ductal cells': '0.541', 'Hepatocytes': '0.600', 'Cholangiocytes': '129.7', 'Proximal tubular cells': '0.042', 'Distal tubular cells': '0.0', 'Collecting duct cells': '143.9', 'Mesothelial cells': '0.799', 'Sertoli cells': '0.252', 'Granulosa cells': '12.9', 'Enteroendocrine cells': '92.4', 'Pancreatic endocrine cells': '78.1', 'Leydig cells': '0.264', 'Excitatory neurons': '0.7', 'Inhibitory neurons': '1.3', 'Cone photoreceptor cells': '0.0', 'Rod photoreceptor cells': '0.0', 'Bipolar cells': '0.2', 'Horizontal cells': '0.6', 'Astrocytes': '0.6', 'Oligodendrocyte precursor cells': '0.5', 'Oligodendrocytes': '29.9', 'Microglial cells': '0.9', 'Muller glia cells': '0.1', 'Schwann cells': '0.131', 'Spermatogonia': '0.392', 'Spermatocytes': '0.193', 'Early spermatids': '-0.217', 'Late spermatids': '-0.290', 'Oocytes': '16.9', 'Cytotrophoblasts': '119.2', 'Syncytiotrophoblasts': '45.0', 'Extravillous trophoblasts': '24.9', 'Endothelial cells': '6.1', 'Lymphatic endothelial cells': '0.4', 'Cardiomyocytes': '0.135', 'Skeletal myocytes': '0.107', 'Smooth muscle cells': '5.8', 'Adipocytes': '2.1', 'Melanocytes': '0.335', 'Fibroblasts': '6.5', 'Peritubular cells': '0.210', 'Endometrial stromal cells': '27.7', 'Ovarian stromal cells': '0.7', 'Undifferentiated cells': '101.6', 'T-cells': '2.9', 'B-cells': '4.4', 'Plasma cells': '6.1', 'Nk-cells': '0.0', 'Granulocytes': '8.4', 'Monocytes': '0.0', 'Macrophages': '6.0', 'Hofbauer cells': '4.3', 'Kupffer cells': '1.0', 'Dendritic cells': '5.9', 'Langerhans cells': '0.304', 'Erythroid cells': '0.036', 'Adipocytes (Subcutaneous)': '-0.081', 'Adipocytes (Visceral)': '-0.209', 'Breast glandular cells (progenitors)': '0.538', 'Adipocytes (Breast)': '-0.689', 'Colon enterocytes': '0.790', 'Colon enteroendocrine cells': '0.112', 'Enteric glia cells': '-0.048', 'Mitotic cells (Colon)': '0.299', 'Mitotic cells (Heart)': '0.120', 'Podocytes': '-0.118', 'Ascending Loop of Henle cells': '0.475', 'Intercalated cells': '0.212', 'Cholangiocyte': '0.090', 'NK-cells (Liver)': '-0.005', 'Respiratory ciliated cells': '-0.012', 'Mitotic cells (Lung)': '0.071', 'NK-cells (Lung)': '-0.266', 'B-cells (Lung)': '-0.296', 'Alpha cells': '0.270', 'Beta cells': '0.152', 'Prostate glandular cells': '0.764', 'Prostate basal glandular cells': '0.540', 'Urothelial cells': '0.205', 'Keratinocyte (other)': '0.510', 'Keratinocyte (granular)': '0.055', 'Hair cortex cells': '0.080', 'Inner root sheath cells': '0.131', 'Outer root sheath cells': '0.175', 'Sebaceous gland cells': '0.156', 'Eccrine sweat gland cells': '-0.207', 'Adipocytes (Skin)': '-0.244', 'Mitotic cells (Skin)': '0.442', 'Parietal cells': '0.654', 'Chief cells': '0.649', 'Gastric mucous cells': '0.781', 'Gastric enteroendocrine cells': '0.590', 'Mitotic cells (Stomach)': '0.445', 'Parafollicular cells': '0.173', 'Thyroid glandular cells': '0.865', 'Mitotic cells (Thyroid)': '-0.081', 'Adrenal cortex cells': '0.051', 'Adrenal medulla cells': '0.087', 'Mitotic cells (Adrenal gland)': '0.072', 'Minor salivary glandular cells': '0.371', 'Minor salivary gland ductal cells': '-0.142', 'Minor salivary gland basal cells': '0.582', 'Mitotic cells (Minor salivary gland)': '0.567', 'Adipocytes (Minor salivary gland)': '0.050', 'Somatotropes': '0.121', 'Lactotropes': '0.322', 'Gonadotropes': '0.330', 'Corticotropes': '0.180', 'Thyrotropes': '0.496', 'Undifferentiated cells (Pituitary gland)': '-0.108', 'Mitotic cells (Spleen)': '-0.228', 'Platelets': '-0.050', 'Erythrocytes': '-0.158', 'Hematopoietic stem cells': '-0.211', 'B-cells (Spleen)': '0.266', 'NK-cells (Spleen)': '0.309', 'Amygdala excitatory': '1.0', 'Cerebellar inhibitory': '0.9', 'Cge interneuron': '0.7', 'Deep-layer corticothalamic and 6b': '1.5', 'Deep-layer intratelencephalic': '0.7', 'Deep-layer near-projecting': '0.7', 'Eccentric medium spiny neuron': '0.6', 'Hippocampal ca1-3': '1.9', 'Hippocampal ca4': '1.2', 'Hippocampal dentate gyrus': '1.1', 'Lamp5-lhx6 and chandelier': '0.5', 'Lower rhombic lip': '0.8', 'Mammillary body': '0.6', 'Medium spiny neuron': '0.7', 'Mge interneuron': '1.7', 'Midbrain-derived inhibitory': '0.7', 'Miscellaneous': '0.9', 'Splatter': '3.8', 'Thalamic excitatory': '0.5', 'Upper rhombic lip': '0.8', 'Upper-layer intratelencephalic': '0.6', 'Astrocyte': '4.4', 'Bergmann glia': '0.2', 'Central nervous system macrophage': '0.6', 'Choroid plexus epithelial cell': '52.1', 'Committed oligodendrocyte precursor': '41.5', 'Ependymal cell': '4.8', 'Oligodendrocyte': '53.1', 'Oligodendrocyte precursor cell': '2.4', 'Endothelial cell': '0.7', 'Pericyte': '0.3', 'Vascular associated smooth muscle cell': '0.0', 'Fibroblast': '17.4', 'Leukocyte': '1.1', 'Basophil': '0.0', 'Eosinophil': '0.0', 'Neutrophil': '0.0', 'Classical monocyte': '0.0', 'Non-classical monocyte': '0.0', 'Intermediate monocyte': '0.0', 'T-reg': '2.3', 'GdT-cell': '0.0', 'MAIT T-cell': '0.0', 'Memory CD4 T-cell': '0.0', 'Naive CD4 T-cell': '0.1', 'Memory CD8 T-cell': '0.2', 'Naive CD8 T-cell': '0.3', 'Memory B-cell': '0.0', 'Naive B-cell': '0.1', 'Plasmacytoid DC': '46.6', 'Myeloid DC': '8.5', 'NK-cell': '0.1', 'Total PBMC': '0.7', 'Vd2 gdTCR': '0.0', 'Memory CD4 T-cell Th1\\/Th17': '0.1', 'Memory CD4 T-cell Th17': '0.2', 'Memory CD4 T-cell Th2': '2.9', 'Non-Vd2 gdTCR': '0.1', 'Memory CD4 T-cell Th1': '0.3', 'Memory CD4 T-cell TFH': '0.5', 'Terminal effector memory CD4 T-cell': '0.0', 'Central memory CD8 T-cell': '4.8', 'Effector memory CD8 T-cell': '0.0', 'Terminal effector memory CD8 T-cell': '0.6', 'Non-switched memory B-cell': '0.0', 'Plasmablast': '3.3', 'Switched memory B-cell': '0.0', 'Exhausted memory B-cell': '0.7', 'Progenitor cell': '2.3', 'Memory T-reg': '1.3', 'Naive CD4 T-cell activated': '0.3', 'Naive CD8 T-cell activated': '0.6', 'Naive T-reg': '0.1'} | 1O6S, 2O72, 2OMT, 2OMU, 2OMV, 2OMX, 2OMY, 2OMZ, 3FF7, 3FF8, 3L6X, 3L6Y, 4ZT1, 4ZTE, 6CXY, 6OLE, 6OLF, 6OLG, 6VEL, 7STZ, 8H62 | {'Adipose Tissue': 1.2125261088039867, 'Adrenal Gland': 0.1914223992248062, 'Bladder': 39.2033519047619, 'Blood': 1.340954264800861, 'Blood Vessel': 0.3121561692883895, 'Brain': 0.8550442199091597, 'Breast': 38.54918344226579, 'Cervix Uteri': 23.539115789473684, 'Colon': 43.41292142490372, 'Esophagus': 53.97513367404844, 'Fallopian Tube': 14.900277777777776, 'Heart': 0.119140469221835, 'Kidney': 25.040449438202245, 'Liver': 26.60802654867257, 'Lung': 35.447986366782004, 'Muscle': 0.1378936151930261, 'Nerve': 17.518468982229404, 'Ovary': 3.6515122222222223, 'Pancreas': 56.89676829268293, 'Pituitary': 24.68741660777385, 'Prostate': 61.279967346938776, 'Salivary Gland': 92.01685185185184, 'Skin': 79.77571720232172, 'Small Intestine': 71.7519320855615, 'Spleen': 10.061029045643156, 'Stomach': 58.07813805013927, 'Testis': 0.8144204986149585, 'Thyroid': 135.176797856049, 'Uterus': 1.442593943661972, 'Vagina': 86.52345512820513} | PIMREG | MASRWQNMGTSVRRRSLQHQEQLEDSKELQPVVSHQETSVGALGSLCRQFQRRLPLRAVNLNLRAGPSWKRLETPEPGQQGLQAAARSAKSALGAVSQRIQESCQSGTKWLVETQVKARRRKRGAQKGSGSPTHSLSQKSTRLSGAAPAHSAADPWEKEHHRLSVRMGSHAHPLRRSRREAAFRSPYSSTEPLCSPSESDSDLEPVGAGIQHLQKLSQELDEAIMAEESGDIVSLIHD | Homo sapiens | null | Not found | {} | null | {} | [39.93, 46.46, 52.9, 44.21, 41.4, 39.93, 35.91, 38.61, 36.44, 36.25, 34.86, 32.82, 32.01, 32.75, 31.69, 35.64, 36.35, 34.66, 33.32, 32.71, 35.01, 30.17, 37.05, 36.53, 48.19, 58.22, 64.94, 73.22, 78.33, 82.63, 85.79, 89.39, 87.89, 85.58, 83.93, 89.1, 89.27, 90.66, 87.86, 86.2, 82.97, 72.75, 73.3, 76.44, 82.38, 82.41, 79.49, 86.6, 76.32, 85.48, 88.69, 84.35, 87.75, 90.57, 88.72, 89.46, 87.48, 85.3, 81.72, 79.46, 77.26, 69.01, 67.1, 62.83, 67.71, 74.96, 82.95, 86.74, 86.35, 86.49, 84.6, 85.99, 85.64, 87.19, 89.23, 89.3, 90.62, 84.21, 85.42, 83.34, 84.28, 89.8, 89.78, 87.53, 87.64, 85.98, 81.31, 80.85, 78.74, 80.15, 70.67, 69.91, 72.91, 77.13, 83.26, 84.67, 90.36, 89.7, 92.74, 89.99, 92.55, 88.84, 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Forms a ternary complex composed of ADAM10, CADH1 and EPHA4, | null | null | KLRG1, SPEF1, DLGAP5, AJAP1, RAPGEF2, RAB8B, PIP5K1C, PKP2, TRPV4, CTNNB1, CAV1, DDR1, TBC1D2, CTNNA1, JUP, CTNND1, PSEN1, LIMA1, CDH1, JUP, ADAM10, CADH1 , EPHA4, | null | null | null | null | Homodimer | null | 79.91949 | 0.474025 | null | null | 2,603 |
P12830 | Q9BW19 | null | degron_data | CDH1 | MGPWSRSLSALLLLLQVSSWLCQEPEPCHPGFDAESYTFTVPRRHLERGRVLGRVNFEDCTGRQRTAYFSLDTRFKVGTDGVITVKRPLRFHNPQIHFLVYAWDSTYRKFSTKVTLNTVGHHHRPPPHQASVSGIQAELLTFPNSSPGLRRQKRDWVIPPISCPENEKGPFPKNLVQIKSNKDKEGKVFYSITGQGADTPPVGVFIIERETGWLKVTEPLDRERIATYTLFSHAVSSNGNAVEDPMEILITVTDQNDNKPEFTQEVFKGSVMEGALPGTSVMEVTATDADDDVNTYNAAIAYTILSQDPELPDKNMFTINRNTGVISVVTTGLDRESFPTYTLVVQAADLQGEGLSTTATAVITVTDTNDNPPIFNPTTYKGQVPENEANVVITTLKVTDADAPNTPAWEAVYTILNDDGGQFVVTTNPVNNDGILKTAKGLDFEAKQQYILHVAVTNVVPFEVSLTTSTATVTVDVLDVNEAPIFVPPEKRVEVSEDFGVGQEITSYTAQEPDTFMEQKITYRIWRDTANWLEINPDTGAISTRAELDREDFEHVKNSTYTALIIATDNGSPVATGTGTLLLILSDVNDNAPIPEPRTIFFCERNPKPQVINIIDADLPPNTSPFTAELTHGASANWTIQYNDPTQESIILKPKMALEVGDYKINLKLMDNQNKDQVTTLEVSVCDCEGAAGVCRKAQPVEAGLQIPAILGILGGILALLILILLLLLFLRRRAVVKEPLLPPEDDTRDNVYYYDEEGGGEEDQDFDLSQLHRGLDARPEVTRNDVAPTLMSVPRYLPRPANPDEIGNFIDENLKAADTDPTAPPYDSLLVFDYEGSGSEAASLSSLNSSESDKDQDYDYLNEWGNRFKKLADMYGGGEDD | Homo sapiens | Cell junction, adherens junction, Cell membrane, Endosome, Golgi apparatus, trans-Golgi network, Cytoplasm, Cell junction, desmosome | Tissue enhanced (parathyroid) | {'Ciliated cells': '119.1', 'Basal respiratory cells': '71.1', 'Club cells': '97.3', 'Ionocytes': '81.0', 'Mucus glandular cells': '155.0', 'Serous glandular cells': '67.8', 'Gastric mucus-secreting cells': '133.2', 'Proximal enterocytes': '140.9', 'Paneth cells': '125.1', 'Distal enterocytes': '307.5', 'Intestinal goblet cells': '173.5', 'Exocrine glandular cells': '-0.605', 'Basal prostatic cells': '68.3', 'Prostatic glandular cells': '186.7', 'Breast glandular cells': '0.773', 'Breast myoepithelial cells': '0.700', 'Glandular and luminal cells': '313.0', 'Secretory cells': '82.3', 'Basal keratinocytes': '102.5', 'Suprabasal keratinocytes': '162.6', 'Basal squamous epithelial cells': '51.0', 'Squamous epithelial cells': '106.9', 'Alveolar cells type 1': '0.437', 'Alveolar cells type 2': '0.706', 'Salivary duct cells': '95.9', 'Ductal cells': '0.541', 'Hepatocytes': '0.600', 'Cholangiocytes': '129.7', 'Proximal tubular cells': '0.042', 'Distal tubular cells': '0.0', 'Collecting duct cells': '143.9', 'Mesothelial cells': '0.799', 'Sertoli cells': '0.252', 'Granulosa cells': '12.9', 'Enteroendocrine cells': '92.4', 'Pancreatic endocrine cells': '78.1', 'Leydig cells': '0.264', 'Excitatory neurons': '0.7', 'Inhibitory neurons': '1.3', 'Cone photoreceptor cells': '0.0', 'Rod photoreceptor cells': '0.0', 'Bipolar cells': '0.2', 'Horizontal cells': '0.6', 'Astrocytes': '0.6', 'Oligodendrocyte precursor cells': '0.5', 'Oligodendrocytes': '29.9', 'Microglial cells': '0.9', 'Muller glia cells': '0.1', 'Schwann cells': '0.131', 'Spermatogonia': '0.392', 'Spermatocytes': '0.193', 'Early spermatids': '-0.217', 'Late spermatids': '-0.290', 'Oocytes': '16.9', 'Cytotrophoblasts': '119.2', 'Syncytiotrophoblasts': '45.0', 'Extravillous trophoblasts': '24.9', 'Endothelial cells': '6.1', 'Lymphatic endothelial cells': '0.4', 'Cardiomyocytes': '0.135', 'Skeletal myocytes': '0.107', 'Smooth muscle cells': '5.8', 'Adipocytes': '2.1', 'Melanocytes': '0.335', 'Fibroblasts': '6.5', 'Peritubular cells': '0.210', 'Endometrial stromal cells': '27.7', 'Ovarian stromal cells': '0.7', 'Undifferentiated cells': '101.6', 'T-cells': '2.9', 'B-cells': '4.4', 'Plasma cells': '6.1', 'Nk-cells': '0.0', 'Granulocytes': '8.4', 'Monocytes': '0.0', 'Macrophages': '6.0', 'Hofbauer cells': '4.3', 'Kupffer cells': '1.0', 'Dendritic cells': '5.9', 'Langerhans cells': '0.304', 'Erythroid cells': '0.036', 'Adipocytes (Subcutaneous)': '-0.081', 'Adipocytes (Visceral)': '-0.209', 'Breast glandular cells (progenitors)': '0.538', 'Adipocytes (Breast)': '-0.689', 'Colon enterocytes': '0.790', 'Colon enteroendocrine cells': '0.112', 'Enteric glia cells': '-0.048', 'Mitotic cells (Colon)': '0.299', 'Mitotic cells (Heart)': '0.120', 'Podocytes': '-0.118', 'Ascending Loop of Henle cells': '0.475', 'Intercalated cells': '0.212', 'Cholangiocyte': '0.090', 'NK-cells (Liver)': '-0.005', 'Respiratory ciliated cells': '-0.012', 'Mitotic cells (Lung)': '0.071', 'NK-cells (Lung)': '-0.266', 'B-cells (Lung)': '-0.296', 'Alpha cells': '0.270', 'Beta cells': '0.152', 'Prostate glandular cells': '0.764', 'Prostate basal glandular cells': '0.540', 'Urothelial cells': '0.205', 'Keratinocyte (other)': '0.510', 'Keratinocyte (granular)': '0.055', 'Hair cortex cells': '0.080', 'Inner root sheath cells': '0.131', 'Outer root sheath cells': '0.175', 'Sebaceous gland cells': '0.156', 'Eccrine sweat gland cells': '-0.207', 'Adipocytes (Skin)': '-0.244', 'Mitotic cells (Skin)': '0.442', 'Parietal cells': '0.654', 'Chief cells': '0.649', 'Gastric mucous cells': '0.781', 'Gastric enteroendocrine cells': '0.590', 'Mitotic cells (Stomach)': '0.445', 'Parafollicular cells': '0.173', 'Thyroid glandular cells': '0.865', 'Mitotic cells (Thyroid)': '-0.081', 'Adrenal cortex cells': '0.051', 'Adrenal medulla cells': '0.087', 'Mitotic cells (Adrenal gland)': '0.072', 'Minor salivary glandular cells': '0.371', 'Minor salivary gland ductal cells': '-0.142', 'Minor salivary gland basal cells': '0.582', 'Mitotic cells (Minor salivary gland)': '0.567', 'Adipocytes (Minor salivary gland)': '0.050', 'Somatotropes': '0.121', 'Lactotropes': '0.322', 'Gonadotropes': '0.330', 'Corticotropes': '0.180', 'Thyrotropes': '0.496', 'Undifferentiated cells (Pituitary gland)': '-0.108', 'Mitotic cells (Spleen)': '-0.228', 'Platelets': '-0.050', 'Erythrocytes': '-0.158', 'Hematopoietic stem cells': '-0.211', 'B-cells (Spleen)': '0.266', 'NK-cells (Spleen)': '0.309', 'Amygdala excitatory': '1.0', 'Cerebellar inhibitory': '0.9', 'Cge interneuron': '0.7', 'Deep-layer corticothalamic and 6b': '1.5', 'Deep-layer intratelencephalic': '0.7', 'Deep-layer near-projecting': '0.7', 'Eccentric medium spiny neuron': '0.6', 'Hippocampal ca1-3': '1.9', 'Hippocampal ca4': '1.2', 'Hippocampal dentate gyrus': '1.1', 'Lamp5-lhx6 and chandelier': '0.5', 'Lower rhombic lip': '0.8', 'Mammillary body': '0.6', 'Medium spiny neuron': '0.7', 'Mge interneuron': '1.7', 'Midbrain-derived inhibitory': '0.7', 'Miscellaneous': '0.9', 'Splatter': '3.8', 'Thalamic excitatory': '0.5', 'Upper rhombic lip': '0.8', 'Upper-layer intratelencephalic': '0.6', 'Astrocyte': '4.4', 'Bergmann glia': '0.2', 'Central nervous system macrophage': '0.6', 'Choroid plexus epithelial cell': '52.1', 'Committed oligodendrocyte precursor': '41.5', 'Ependymal cell': '4.8', 'Oligodendrocyte': '53.1', 'Oligodendrocyte precursor cell': '2.4', 'Endothelial cell': '0.7', 'Pericyte': '0.3', 'Vascular associated smooth muscle cell': '0.0', 'Fibroblast': '17.4', 'Leukocyte': '1.1', 'Basophil': '0.0', 'Eosinophil': '0.0', 'Neutrophil': '0.0', 'Classical monocyte': '0.0', 'Non-classical monocyte': '0.0', 'Intermediate monocyte': '0.0', 'T-reg': '2.3', 'GdT-cell': '0.0', 'MAIT T-cell': '0.0', 'Memory CD4 T-cell': '0.0', 'Naive CD4 T-cell': '0.1', 'Memory CD8 T-cell': '0.2', 'Naive CD8 T-cell': '0.3', 'Memory B-cell': '0.0', 'Naive B-cell': '0.1', 'Plasmacytoid DC': '46.6', 'Myeloid DC': '8.5', 'NK-cell': '0.1', 'Total PBMC': '0.7', 'Vd2 gdTCR': '0.0', 'Memory CD4 T-cell Th1\\/Th17': '0.1', 'Memory CD4 T-cell Th17': '0.2', 'Memory CD4 T-cell Th2': '2.9', 'Non-Vd2 gdTCR': '0.1', 'Memory CD4 T-cell Th1': '0.3', 'Memory CD4 T-cell TFH': '0.5', 'Terminal effector memory CD4 T-cell': '0.0', 'Central memory CD8 T-cell': '4.8', 'Effector memory CD8 T-cell': '0.0', 'Terminal effector memory CD8 T-cell': '0.6', 'Non-switched memory B-cell': '0.0', 'Plasmablast': '3.3', 'Switched memory B-cell': '0.0', 'Exhausted memory B-cell': '0.7', 'Progenitor cell': '2.3', 'Memory T-reg': '1.3', 'Naive CD4 T-cell activated': '0.3', 'Naive CD8 T-cell activated': '0.6', 'Naive T-reg': '0.1'} | 1O6S, 2O72, 2OMT, 2OMU, 2OMV, 2OMX, 2OMY, 2OMZ, 3FF7, 3FF8, 3L6X, 3L6Y, 4ZT1, 4ZTE, 6CXY, 6OLE, 6OLF, 6OLG, 6VEL, 7STZ, 8H62 | {'Adipose Tissue': 1.2125261088039867, 'Adrenal Gland': 0.1914223992248062, 'Bladder': 39.2033519047619, 'Blood': 1.340954264800861, 'Blood Vessel': 0.3121561692883895, 'Brain': 0.8550442199091597, 'Breast': 38.54918344226579, 'Cervix Uteri': 23.539115789473684, 'Colon': 43.41292142490372, 'Esophagus': 53.97513367404844, 'Fallopian Tube': 14.900277777777776, 'Heart': 0.119140469221835, 'Kidney': 25.040449438202245, 'Liver': 26.60802654867257, 'Lung': 35.447986366782004, 'Muscle': 0.1378936151930261, 'Nerve': 17.518468982229404, 'Ovary': 3.6515122222222223, 'Pancreas': 56.89676829268293, 'Pituitary': 24.68741660777385, 'Prostate': 61.279967346938776, 'Salivary Gland': 92.01685185185184, 'Skin': 79.77571720232172, 'Small Intestine': 71.7519320855615, 'Spleen': 10.061029045643156, 'Stomach': 58.07813805013927, 'Testis': 0.8144204986149585, 'Thyroid': 135.176797856049, 'Uterus': 1.442593943661972, 'Vagina': 86.52345512820513} | KIFC1 | MDPQRSPLLEVKGNIELKRPLIKAPSQLPLSGSRLKRRPDQMEDGLEPEKKRTRGLGATTKITTSHPRVPSLTTVPQTQGQTTAQKVSKKTGPRCSTAIATGLKNQKPVPAVPVQKSGTSGVPPMAGGKKPSKRPAWDLKGQLCDLNAELKRCRERTQTLDQENQQLQDQLRDAQQQVKALGTERTTLEGHLAKVQAQAEQGQQELKNLRACVLELEERLSTQEGLVQELQKKQVELQEERRGLMSQLEEKERRLQTSEAALSSSQAEVASLRQETVAQAALLTEREERLHGLEMERRRLHNQLQELKGNIRVFCRVRPVLPGEPTPPPGLLLFPSGPGGPSDPPTRLSLSRSDERRGTLSGAPAPPTRHDFSFDRVFPPGSGQDEVFEEIAMLVQSALDGYPVCIFAYGQTGSGKTFTMEGGPGGDPQLEGLIPRALRHLFSVAQELSGQGWTYSFVASYVEIYNETVRDLLATGTRKGQGGECEIRRAGPGSEELTVTNARYVPVSCEKEVDALLHLARQNRAVARTAQNERSSRSHSVFQLQISGEHSSRGLQCGAPLSLVDLAGSERLDPGLALGPGERERLRETQAINSSLSTLGLVIMALSNKESHVPYRNSKLTYLLQNSLGGSAKMLMFVNISPLEENVSESLNSLRFASKVNQCVIGTAQANRK | Homo sapiens | Nucleus, Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, Cytoplasm, cytoskeleton, spindle, Early endosome | Tissue enhanced (bone marrow, lymphoid tissue) | {'Ciliated cells': '1.4', 'Basal respiratory cells': '4.1', 'Club cells': '1.6', 'Ionocytes': '1.1', 'Mucus glandular cells': '1.2', 'Serous glandular cells': '2.4', 'Gastric mucus-secreting cells': '4.7', 'Proximal enterocytes': '0.4', 'Paneth cells': '1.6', 'Distal enterocytes': '1.8', 'Intestinal goblet cells': '5.2', 'Exocrine glandular cells': '-0.392', 'Basal prostatic cells': '0.2', 'Prostatic glandular cells': '0.1', 'Breast glandular cells': '0.654', 'Breast myoepithelial cells': '0.451', 'Glandular and luminal cells': '6.0', 'Secretory cells': '0.6', 'Basal keratinocytes': '7.7', 'Suprabasal keratinocytes': '2.9', 'Basal squamous epithelial cells': '5.1', 'Squamous epithelial cells': '12.9', 'Alveolar cells type 1': '-0.038', 'Alveolar cells type 2': '0.161', 'Salivary duct cells': '1.0', 'Ductal cells': '0.487', 'Hepatocytes': '0.340', 'Cholangiocytes': '0.0', 'Proximal tubular cells': '0.214', 'Distal tubular cells': '0.0', 'Collecting duct cells': '0.0', 'Mesothelial cells': '0.193', 'Sertoli cells': '-0.131', 'Granulosa cells': '3.7', 'Enteroendocrine cells': '1.8', 'Pancreatic endocrine cells': '1.7', 'Leydig cells': '-0.188', 'Excitatory neurons': '0.3', 'Inhibitory neurons': '0.3', 'Cone photoreceptor cells': '0.0', 'Rod photoreceptor cells': '0.4', 'Bipolar cells': '0.2', 'Horizontal cells': '0.0', 'Astrocytes': '0.9', 'Oligodendrocyte precursor cells': '0.9', 'Oligodendrocytes': '0.6', 'Microglial cells': '0.9', 'Muller glia cells': '0.5', 'Schwann cells': '0.104', 'Spermatogonia': '0.251', 'Spermatocytes': '0.674', 'Early spermatids': '0.303', 'Late spermatids': '0.214', 'Oocytes': '22.1', 'Cytotrophoblasts': '16.6', 'Syncytiotrophoblasts': '3.3', 'Extravillous trophoblasts': '37.6', 'Endothelial cells': '1.2', 'Lymphatic endothelial cells': '0.0', 'Cardiomyocytes': '0.332', 'Skeletal myocytes': '-0.017', 'Smooth muscle cells': '1.4', 'Adipocytes': '0.4', 'Melanocytes': '0.432', 'Fibroblasts': '2.8', 'Peritubular cells': '-0.230', 'Endometrial stromal cells': '1.3', 'Ovarian stromal cells': '1.8', 'Undifferentiated cells': '21.1', 'T-cells': '4.6', 'B-cells': '3.0', 'Plasma cells': '17.0', 'Nk-cells': '1.8', 'Granulocytes': '1.0', 'Monocytes': '4.1', 'Macrophages': '4.6', 'Hofbauer cells': '9.7', 'Kupffer cells': '1.8', 'Dendritic cells': '3.2', 'Langerhans cells': '0.202', 'Erythroid cells': '0.106', 'Adipocytes (Subcutaneous)': '-0.206', 'Adipocytes (Visceral)': '-0.112', 'Breast glandular cells (progenitors)': '0.385', 'Adipocytes (Breast)': '-0.441', 'Colon enterocytes': '0.333', 'Colon enteroendocrine cells': '-0.118', 'Enteric glia cells': '-0.195', 'Mitotic cells (Colon)': '0.651', 'Mitotic cells (Heart)': '0.890', 'Podocytes': '-0.166', 'Ascending Loop of Henle cells': '0.362', 'Intercalated cells': '-0.031', 'Cholangiocyte': '0.357', 'NK-cells (Liver)': '-0.092', 'Respiratory ciliated cells': '0.008', 'Mitotic cells (Lung)': '0.808', 'NK-cells (Lung)': '0.017', 'B-cells (Lung)': '0.060', 'Alpha cells': '0.209', 'Beta cells': '0.053', 'Prostate glandular cells': '0.296', 'Prostate basal glandular cells': '0.287', 'Urothelial cells': '0.164', 'Keratinocyte (other)': '0.228', 'Keratinocyte (granular)': '-0.190', 'Hair cortex cells': '0.103', 'Inner root sheath cells': '0.213', 'Outer root sheath cells': '0.266', 'Sebaceous gland cells': '0.124', 'Eccrine sweat gland cells': '0.078', 'Adipocytes (Skin)': '-0.096', 'Mitotic cells (Skin)': '0.927', 'Parietal cells': '0.105', 'Chief cells': '0.059', 'Gastric mucous cells': '0.548', 'Gastric enteroendocrine cells': '0.168', 'Mitotic cells (Stomach)': '0.958', 'Parafollicular cells': '0.061', 'Thyroid glandular cells': '0.142', 'Mitotic cells (Thyroid)': '0.634', 'Adrenal cortex cells': '0.411', 'Adrenal medulla cells': '0.112', 'Mitotic cells (Adrenal gland)': '0.896', 'Minor salivary glandular cells': '0.146', 'Minor salivary gland ductal cells': '-0.299', 'Minor salivary gland basal cells': '0.691', 'Mitotic cells (Minor salivary gland)': '0.959', 'Adipocytes (Minor salivary gland)': '0.168', 'Somatotropes': '-0.048', 'Lactotropes': '-0.123', 'Gonadotropes': '0.021', 'Corticotropes': '-0.117', 'Thyrotropes': '-0.025', 'Undifferentiated cells (Pituitary gland)': '0.213', 'Mitotic cells (Spleen)': '0.933', 'Platelets': '0.193', 'Erythrocytes': '0.300', 'Hematopoietic stem cells': '0.414', 'B-cells (Spleen)': '-0.134', 'NK-cells (Spleen)': '-0.243', 'Amygdala excitatory': '0.3', 'Cerebellar inhibitory': '0.2', 'Cge interneuron': '0.2', 'Deep-layer corticothalamic and 6b': '0.5', 'Deep-layer intratelencephalic': '0.3', 'Deep-layer near-projecting': '0.6', 'Eccentric medium spiny neuron': '0.3', 'Hippocampal ca1-3': '0.3', 'Hippocampal ca4': '0.7', 'Hippocampal dentate gyrus': '0.2', 'Lamp5-lhx6 and chandelier': '0.2', 'Lower rhombic lip': '0.8', 'Mammillary body': '0.2', 'Medium spiny neuron': '0.4', 'Mge interneuron': '0.3', 'Midbrain-derived inhibitory': '0.1', 'Miscellaneous': '0.3', 'Splatter': '0.3', 'Thalamic excitatory': '0.1', 'Upper rhombic lip': '0.1', 'Upper-layer intratelencephalic': '0.3', 'Astrocyte': '0.4', 'Bergmann glia': '0.8', 'Central nervous system macrophage': '1.0', 'Choroid plexus epithelial cell': '0.2', 'Committed oligodendrocyte precursor': '0.3', 'Ependymal cell': '0.3', 'Oligodendrocyte': '0.6', 'Oligodendrocyte precursor cell': '0.6', 'Endothelial cell': '0.7', 'Pericyte': '0.1', 'Vascular associated smooth muscle cell': '1.1', 'Fibroblast': '2.8', 'Leukocyte': '1.5', 'Basophil': '2.1', 'Eosinophil': '0.0', 'Neutrophil': '0.5', 'Classical monocyte': '0.7', 'Non-classical monocyte': '0.8', 'Intermediate monocyte': '1.5', 'T-reg': '7.8', 'GdT-cell': '0.1', 'MAIT T-cell': '0.1', 'Memory CD4 T-cell': '0.1', 'Naive CD4 T-cell': '0.4', 'Memory CD8 T-cell': '0.6', 'Naive CD8 T-cell': '0.4', 'Memory B-cell': '0.2', 'Naive B-cell': '0.2', 'Plasmacytoid DC': '0.1', 'Myeloid DC': '2.9', 'NK-cell': '2.1', 'Total PBMC': '4.4', 'Vd2 gdTCR': '1.2', 'Memory CD4 T-cell Th1\\/Th17': '0.4', 'Memory CD4 T-cell Th17': '1.1', 'Memory CD4 T-cell Th2': '1.3', 'Non-Vd2 gdTCR': '1.8', 'Memory CD4 T-cell Th1': '1.6', 'Memory CD4 T-cell TFH': '1.2', 'Terminal effector memory CD4 T-cell': '1.1', 'Central memory CD8 T-cell': '3.2', 'Effector memory CD8 T-cell': '7.3', 'Terminal effector memory CD8 T-cell': '2.5', 'Non-switched memory B-cell': '1.3', 'Plasmablast': '54.0', 'Switched memory B-cell': '3.1', 'Exhausted memory B-cell': '6.8', 'Progenitor cell': '0.7', 'Memory T-reg': '5.4', 'Naive CD4 T-cell activated': '0.7', 'Naive CD8 T-cell activated': '1.2', 'Naive T-reg': '0.7'} | 5WDH | {'Adipose Tissue': 1.382284941860465, 'Adrenal Gland': 1.4082185271317829, 'Bladder': 1.3421190476190477, 'Blood': 18.739540075349836, 'Blood Vessel': 0.8594463071161049, 'Brain': 0.2872865174110522, 'Breast': 4.053933877995643, 'Cervix Uteri': 2.545968421052631, 'Colon': 3.6692371245186135, 'Esophagus': 6.165866844290657, 'Fallopian Tube': 1.5988444444444443, 'Heart': 0.3875638722415795, 'Kidney': 0.8146791011235954, 'Liver': 0.7714212389380531, 'Lung': 4.1580712802768165, 'Muscle': 0.173771603985056, 'Nerve': 1.0527096930533115, 'Ovary': 3.627610555555556, 'Pancreas': 0.416666219512195, 'Pituitary': 1.0019238869257951, 'Prostate': 1.616406, 'Salivary Gland': 2.916056790123457, 'Skin': 16.427071752349367, 'Small Intestine': 7.408389304812834, 'Spleen': 7.606529460580913, 'Stomach': 3.543790445682451, 'Testis': 25.981939058171744, 'Thyroid': 1.4404921898928025, 'Uterus': 1.7768323943661972, 'Vagina': 6.082370512820512} | [39.93, 46.46, 52.9, 44.21, 41.4, 39.93, 35.91, 38.61, 36.44, 36.25, 34.86, 32.82, 32.01, 32.75, 31.69, 35.64, 36.35, 34.66, 33.32, 32.71, 35.01, 30.17, 37.05, 36.53, 48.19, 58.22, 64.94, 73.22, 78.33, 82.63, 85.79, 89.39, 87.89, 85.58, 83.93, 89.1, 89.27, 90.66, 87.86, 86.2, 82.97, 72.75, 73.3, 76.44, 82.38, 82.41, 79.49, 86.6, 76.32, 85.48, 88.69, 84.35, 87.75, 90.57, 88.72, 89.46, 87.48, 85.3, 81.72, 79.46, 77.26, 69.01, 67.1, 62.83, 67.71, 74.96, 82.95, 86.74, 86.35, 86.49, 84.6, 85.99, 85.64, 87.19, 89.23, 89.3, 90.62, 84.21, 85.42, 83.34, 84.28, 89.8, 89.78, 87.53, 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Forms a ternary complex composed of ADAM10, CADH1 and EPHA4, | null | null | KLRG1, SPEF1, DLGAP5, AJAP1, RAPGEF2, RAB8B, PIP5K1C, PKP2, TRPV4, CTNNB1, CAV1, DDR1, TBC1D2, CTNNA1, JUP, CTNND1, PSEN1, LIMA1, CDH1, JUP, ADAM10, CADH1 , EPHA4, | null | null | null | null | Homodimer | null | 79.91949 | 0.474025 | 77.361605 | 0.49159 | 1,075 |
P12830 | Q9BXS6 | null | degron_data | CDH1 | MGPWSRSLSALLLLLQVSSWLCQEPEPCHPGFDAESYTFTVPRRHLERGRVLGRVNFEDCTGRQRTAYFSLDTRFKVGTDGVITVKRPLRFHNPQIHFLVYAWDSTYRKFSTKVTLNTVGHHHRPPPHQASVSGIQAELLTFPNSSPGLRRQKRDWVIPPISCPENEKGPFPKNLVQIKSNKDKEGKVFYSITGQGADTPPVGVFIIERETGWLKVTEPLDRERIATYTLFSHAVSSNGNAVEDPMEILITVTDQNDNKPEFTQEVFKGSVMEGALPGTSVMEVTATDADDDVNTYNAAIAYTILSQDPELPDKNMFTINRNTGVISVVTTGLDRESFPTYTLVVQAADLQGEGLSTTATAVITVTDTNDNPPIFNPTTYKGQVPENEANVVITTLKVTDADAPNTPAWEAVYTILNDDGGQFVVTTNPVNNDGILKTAKGLDFEAKQQYILHVAVTNVVPFEVSLTTSTATVTVDVLDVNEAPIFVPPEKRVEVSEDFGVGQEITSYTAQEPDTFMEQKITYRIWRDTANWLEINPDTGAISTRAELDREDFEHVKNSTYTALIIATDNGSPVATGTGTLLLILSDVNDNAPIPEPRTIFFCERNPKPQVINIIDADLPPNTSPFTAELTHGASANWTIQYNDPTQESIILKPKMALEVGDYKINLKLMDNQNKDQVTTLEVSVCDCEGAAGVCRKAQPVEAGLQIPAILGILGGILALLILILLLLLFLRRRAVVKEPLLPPEDDTRDNVYYYDEEGGGEEDQDFDLSQLHRGLDARPEVTRNDVAPTLMSVPRYLPRPANPDEIGNFIDENLKAADTDPTAPPYDSLLVFDYEGSGSEAASLSSLNSSESDKDQDYDYLNEWGNRFKKLADMYGGGEDD | Homo sapiens | Cell junction, adherens junction, Cell membrane, Endosome, Golgi apparatus, trans-Golgi network, Cytoplasm, Cell junction, desmosome | Tissue enhanced (parathyroid) | {'Ciliated cells': '119.1', 'Basal respiratory cells': '71.1', 'Club cells': '97.3', 'Ionocytes': '81.0', 'Mucus glandular cells': '155.0', 'Serous glandular cells': '67.8', 'Gastric mucus-secreting cells': '133.2', 'Proximal enterocytes': '140.9', 'Paneth cells': '125.1', 'Distal enterocytes': '307.5', 'Intestinal goblet cells': '173.5', 'Exocrine glandular cells': '-0.605', 'Basal prostatic cells': '68.3', 'Prostatic glandular cells': '186.7', 'Breast glandular cells': '0.773', 'Breast myoepithelial cells': '0.700', 'Glandular and luminal cells': '313.0', 'Secretory cells': '82.3', 'Basal keratinocytes': '102.5', 'Suprabasal keratinocytes': '162.6', 'Basal squamous epithelial cells': '51.0', 'Squamous epithelial cells': '106.9', 'Alveolar cells type 1': '0.437', 'Alveolar cells type 2': '0.706', 'Salivary duct cells': '95.9', 'Ductal cells': '0.541', 'Hepatocytes': '0.600', 'Cholangiocytes': '129.7', 'Proximal tubular cells': '0.042', 'Distal tubular cells': '0.0', 'Collecting duct cells': '143.9', 'Mesothelial cells': '0.799', 'Sertoli cells': '0.252', 'Granulosa cells': '12.9', 'Enteroendocrine cells': '92.4', 'Pancreatic endocrine cells': '78.1', 'Leydig cells': '0.264', 'Excitatory neurons': '0.7', 'Inhibitory neurons': '1.3', 'Cone photoreceptor cells': '0.0', 'Rod photoreceptor cells': '0.0', 'Bipolar cells': '0.2', 'Horizontal cells': '0.6', 'Astrocytes': '0.6', 'Oligodendrocyte precursor cells': '0.5', 'Oligodendrocytes': '29.9', 'Microglial cells': '0.9', 'Muller glia cells': '0.1', 'Schwann cells': '0.131', 'Spermatogonia': '0.392', 'Spermatocytes': '0.193', 'Early spermatids': '-0.217', 'Late spermatids': '-0.290', 'Oocytes': '16.9', 'Cytotrophoblasts': '119.2', 'Syncytiotrophoblasts': '45.0', 'Extravillous trophoblasts': '24.9', 'Endothelial cells': '6.1', 'Lymphatic endothelial cells': '0.4', 'Cardiomyocytes': '0.135', 'Skeletal myocytes': '0.107', 'Smooth muscle cells': '5.8', 'Adipocytes': '2.1', 'Melanocytes': '0.335', 'Fibroblasts': '6.5', 'Peritubular cells': '0.210', 'Endometrial stromal cells': '27.7', 'Ovarian stromal cells': '0.7', 'Undifferentiated cells': '101.6', 'T-cells': '2.9', 'B-cells': '4.4', 'Plasma cells': '6.1', 'Nk-cells': '0.0', 'Granulocytes': '8.4', 'Monocytes': '0.0', 'Macrophages': '6.0', 'Hofbauer cells': '4.3', 'Kupffer cells': '1.0', 'Dendritic cells': '5.9', 'Langerhans cells': '0.304', 'Erythroid cells': '0.036', 'Adipocytes (Subcutaneous)': '-0.081', 'Adipocytes (Visceral)': '-0.209', 'Breast glandular cells (progenitors)': '0.538', 'Adipocytes (Breast)': '-0.689', 'Colon enterocytes': '0.790', 'Colon enteroendocrine cells': '0.112', 'Enteric glia cells': '-0.048', 'Mitotic cells (Colon)': '0.299', 'Mitotic cells (Heart)': '0.120', 'Podocytes': '-0.118', 'Ascending Loop of Henle cells': '0.475', 'Intercalated cells': '0.212', 'Cholangiocyte': '0.090', 'NK-cells (Liver)': '-0.005', 'Respiratory ciliated cells': '-0.012', 'Mitotic cells (Lung)': '0.071', 'NK-cells (Lung)': '-0.266', 'B-cells (Lung)': '-0.296', 'Alpha cells': '0.270', 'Beta cells': '0.152', 'Prostate glandular cells': '0.764', 'Prostate basal glandular cells': '0.540', 'Urothelial cells': '0.205', 'Keratinocyte (other)': '0.510', 'Keratinocyte (granular)': '0.055', 'Hair cortex cells': '0.080', 'Inner root sheath cells': '0.131', 'Outer root sheath cells': '0.175', 'Sebaceous gland cells': '0.156', 'Eccrine sweat gland cells': '-0.207', 'Adipocytes (Skin)': '-0.244', 'Mitotic cells (Skin)': '0.442', 'Parietal cells': '0.654', 'Chief cells': '0.649', 'Gastric mucous cells': '0.781', 'Gastric enteroendocrine cells': '0.590', 'Mitotic cells (Stomach)': '0.445', 'Parafollicular cells': '0.173', 'Thyroid glandular cells': '0.865', 'Mitotic cells (Thyroid)': '-0.081', 'Adrenal cortex cells': '0.051', 'Adrenal medulla cells': '0.087', 'Mitotic cells (Adrenal gland)': '0.072', 'Minor salivary glandular cells': '0.371', 'Minor salivary gland ductal cells': '-0.142', 'Minor salivary gland basal cells': '0.582', 'Mitotic cells (Minor salivary gland)': '0.567', 'Adipocytes (Minor salivary gland)': '0.050', 'Somatotropes': '0.121', 'Lactotropes': '0.322', 'Gonadotropes': '0.330', 'Corticotropes': '0.180', 'Thyrotropes': '0.496', 'Undifferentiated cells (Pituitary gland)': '-0.108', 'Mitotic cells (Spleen)': '-0.228', 'Platelets': '-0.050', 'Erythrocytes': '-0.158', 'Hematopoietic stem cells': '-0.211', 'B-cells (Spleen)': '0.266', 'NK-cells (Spleen)': '0.309', 'Amygdala excitatory': '1.0', 'Cerebellar inhibitory': '0.9', 'Cge interneuron': '0.7', 'Deep-layer corticothalamic and 6b': '1.5', 'Deep-layer intratelencephalic': '0.7', 'Deep-layer near-projecting': '0.7', 'Eccentric medium spiny neuron': '0.6', 'Hippocampal ca1-3': '1.9', 'Hippocampal ca4': '1.2', 'Hippocampal dentate gyrus': '1.1', 'Lamp5-lhx6 and chandelier': '0.5', 'Lower rhombic lip': '0.8', 'Mammillary body': '0.6', 'Medium spiny neuron': '0.7', 'Mge interneuron': '1.7', 'Midbrain-derived inhibitory': '0.7', 'Miscellaneous': '0.9', 'Splatter': '3.8', 'Thalamic excitatory': '0.5', 'Upper rhombic lip': '0.8', 'Upper-layer intratelencephalic': '0.6', 'Astrocyte': '4.4', 'Bergmann glia': '0.2', 'Central nervous system macrophage': '0.6', 'Choroid plexus epithelial cell': '52.1', 'Committed oligodendrocyte precursor': '41.5', 'Ependymal cell': '4.8', 'Oligodendrocyte': '53.1', 'Oligodendrocyte precursor cell': '2.4', 'Endothelial cell': '0.7', 'Pericyte': '0.3', 'Vascular associated smooth muscle cell': '0.0', 'Fibroblast': '17.4', 'Leukocyte': '1.1', 'Basophil': '0.0', 'Eosinophil': '0.0', 'Neutrophil': '0.0', 'Classical monocyte': '0.0', 'Non-classical monocyte': '0.0', 'Intermediate monocyte': '0.0', 'T-reg': '2.3', 'GdT-cell': '0.0', 'MAIT T-cell': '0.0', 'Memory CD4 T-cell': '0.0', 'Naive CD4 T-cell': '0.1', 'Memory CD8 T-cell': '0.2', 'Naive CD8 T-cell': '0.3', 'Memory B-cell': '0.0', 'Naive B-cell': '0.1', 'Plasmacytoid DC': '46.6', 'Myeloid DC': '8.5', 'NK-cell': '0.1', 'Total PBMC': '0.7', 'Vd2 gdTCR': '0.0', 'Memory CD4 T-cell Th1\\/Th17': '0.1', 'Memory CD4 T-cell Th17': '0.2', 'Memory CD4 T-cell Th2': '2.9', 'Non-Vd2 gdTCR': '0.1', 'Memory CD4 T-cell Th1': '0.3', 'Memory CD4 T-cell TFH': '0.5', 'Terminal effector memory CD4 T-cell': '0.0', 'Central memory CD8 T-cell': '4.8', 'Effector memory CD8 T-cell': '0.0', 'Terminal effector memory CD8 T-cell': '0.6', 'Non-switched memory B-cell': '0.0', 'Plasmablast': '3.3', 'Switched memory B-cell': '0.0', 'Exhausted memory B-cell': '0.7', 'Progenitor cell': '2.3', 'Memory T-reg': '1.3', 'Naive CD4 T-cell activated': '0.3', 'Naive CD8 T-cell activated': '0.6', 'Naive T-reg': '0.1'} | 1O6S, 2O72, 2OMT, 2OMU, 2OMV, 2OMX, 2OMY, 2OMZ, 3FF7, 3FF8, 3L6X, 3L6Y, 4ZT1, 4ZTE, 6CXY, 6OLE, 6OLF, 6OLG, 6VEL, 7STZ, 8H62 | {'Adipose Tissue': 1.2125261088039867, 'Adrenal Gland': 0.1914223992248062, 'Bladder': 39.2033519047619, 'Blood': 1.340954264800861, 'Blood Vessel': 0.3121561692883895, 'Brain': 0.8550442199091597, 'Breast': 38.54918344226579, 'Cervix Uteri': 23.539115789473684, 'Colon': 43.41292142490372, 'Esophagus': 53.97513367404844, 'Fallopian Tube': 14.900277777777776, 'Heart': 0.119140469221835, 'Kidney': 25.040449438202245, 'Liver': 26.60802654867257, 'Lung': 35.447986366782004, 'Muscle': 0.1378936151930261, 'Nerve': 17.518468982229404, 'Ovary': 3.6515122222222223, 'Pancreas': 56.89676829268293, 'Pituitary': 24.68741660777385, 'Prostate': 61.279967346938776, 'Salivary Gland': 92.01685185185184, 'Skin': 79.77571720232172, 'Small Intestine': 71.7519320855615, 'Spleen': 10.061029045643156, 'Stomach': 58.07813805013927, 'Testis': 0.8144204986149585, 'Thyroid': 135.176797856049, 'Uterus': 1.442593943661972, 'Vagina': 86.52345512820513} | NUSAP1 | MIIPSLEELDSLKYSDLQNLAKSLGLRANLRATKLLKALKGYIKHEARKGNENQDESQTSASSCDETEIQISNQEEAERQPLGHVTKTRRRCKTVRVDPDSQQNHSEIKISNPTEFQNHEKQESQDLRATAKVPSPPDEHQEAENAVSSGNRDSKVPSEGKKSLYTDESSKPGKNKRTAITTPNFKKLHEAHFKEMESIDQYIERKKKHFEEHNSMNELKQQPINKGGVRTPVPPRGRLSVASTPISQRRSQGRSCGPASQSTLGLKGSLKRSAISAAKTGVRFSAATKDNEHKRSLTKTPARKSAHVTVSGGTPKGEAVLGTHKLKTITGNSAAVITPFKLTTEATQTPVSNKKPVFDLKASLSRPLNYEPHKGKLKPWGQSKENNYLNQHVNRINFYKKTYKQPHLQTKEEQRKKREQERKEKKAKVLGMRRGLILAED | Homo sapiens | Cytoplasm, Nucleus, nucleolus, Cytoplasm, cytoskeleton, spindle, Chromosome | Group enriched (bone marrow, lymphoid tissue) | {'Ciliated cells': '0.5', 'Basal respiratory cells': '2.6', 'Club cells': '0.7', 'Ionocytes': '1.1', 'Mucus glandular cells': '0.2', 'Serous glandular cells': '4.4', 'Gastric mucus-secreting cells': '2.9', 'Proximal enterocytes': '0.6', 'Paneth cells': '0.1', 'Distal enterocytes': '0.2', 'Intestinal goblet cells': '2.9', 'Exocrine glandular cells': '-0.348', 'Basal prostatic cells': '1.2', 'Prostatic glandular cells': '0.0', 'Breast glandular cells': '0.280', 'Breast myoepithelial cells': '0.280', 'Glandular and luminal cells': '2.0', 'Secretory cells': '0.4', 'Basal keratinocytes': '6.5', 'Suprabasal keratinocytes': '3.0', 'Basal squamous epithelial cells': '4.4', 'Squamous epithelial cells': '5.5', 'Alveolar cells type 1': '-0.250', 'Alveolar cells type 2': '0.051', 'Salivary duct cells': '0.4', 'Ductal cells': '0.551', 'Hepatocytes': '0.495', 'Cholangiocytes': '1.9', 'Proximal tubular cells': '0.525', 'Distal tubular cells': '0.0', 'Collecting duct cells': '0.0', 'Mesothelial cells': '0.076', 'Sertoli cells': '-0.381', 'Granulosa cells': '1.2', 'Enteroendocrine cells': '1.0', 'Pancreatic endocrine cells': '10.2', 'Leydig cells': '-0.301', 'Excitatory neurons': '1.3', 'Inhibitory neurons': '1.4', 'Cone photoreceptor cells': '0.0', 'Rod photoreceptor cells': '0.0', 'Bipolar cells': '0.0', 'Horizontal cells': '0.0', 'Astrocytes': '1.2', 'Oligodendrocyte precursor cells': '0.9', 'Oligodendrocytes': '1.2', 'Microglial cells': '1.8', 'Muller glia cells': '0.0', 'Schwann cells': '0.022', 'Spermatogonia': '-0.069', 'Spermatocytes': '0.437', 'Early spermatids': '0.763', 'Late spermatids': '0.363', 'Oocytes': '2.2', 'Cytotrophoblasts': '11.3', 'Syncytiotrophoblasts': '3.8', 'Extravillous trophoblasts': '16.7', 'Endothelial cells': '0.6', 'Lymphatic endothelial cells': '0.0', 'Cardiomyocytes': '0.371', 'Skeletal myocytes': '0.429', 'Smooth muscle cells': '0.6', 'Adipocytes': '0.1', 'Melanocytes': '0.542', 'Fibroblasts': '1.9', 'Peritubular cells': '-0.237', 'Endometrial stromal cells': '0.6', 'Ovarian stromal cells': '1.4', 'Undifferentiated cells': '16.9', 'T-cells': '3.1', 'B-cells': '0.7', 'Plasma cells': '7.0', 'Nk-cells': '2.2', 'Granulocytes': '0.1', 'Monocytes': '0.7', 'Macrophages': '2.6', 'Hofbauer cells': '4.3', 'Kupffer cells': '1.4', 'Dendritic cells': '1.2', 'Langerhans cells': '0.238', 'Erythroid cells': '0.046', 'Adipocytes (Subcutaneous)': '-0.114', 'Adipocytes (Visceral)': '-0.172', 'Breast glandular cells (progenitors)': '0.308', 'Adipocytes (Breast)': '-0.244', 'Colon enterocytes': '0.262', 'Colon enteroendocrine cells': '-0.038', 'Enteric glia cells': '-0.185', 'Mitotic cells (Colon)': '0.734', 'Mitotic cells (Heart)': '0.792', 'Podocytes': '0.001', 'Ascending Loop of Henle cells': '0.060', 'Intercalated cells': '-0.105', 'Cholangiocyte': '0.281', 'NK-cells (Liver)': '-0.239', 'Respiratory ciliated cells': '-0.004', 'Mitotic cells (Lung)': '0.875', 'NK-cells (Lung)': '-0.051', 'B-cells (Lung)': '0.090', 'Alpha cells': '0.214', 'Beta cells': '0.089', 'Prostate glandular cells': '-0.270', 'Prostate basal glandular cells': '0.163', 'Urothelial cells': '0.292', 'Keratinocyte (other)': '0.316', 'Keratinocyte (granular)': '-0.213', 'Hair cortex cells': '0.085', 'Inner root sheath cells': '0.242', 'Outer root sheath cells': '0.264', 'Sebaceous gland cells': '0.092', 'Eccrine sweat gland cells': '-0.060', 'Adipocytes (Skin)': '-0.210', 'Mitotic cells (Skin)': '0.911', 'Parietal cells': '0.092', 'Chief cells': '0.037', 'Gastric mucous cells': '0.543', 'Gastric enteroendocrine cells': '0.168', 'Mitotic cells (Stomach)': '0.943', 'Parafollicular cells': '-0.058', 'Thyroid glandular cells': '-0.151', 'Mitotic cells (Thyroid)': '0.784', 'Adrenal cortex cells': '0.511', 'Adrenal medulla cells': '-0.079', 'Mitotic cells (Adrenal gland)': '0.372', 'Minor salivary glandular cells': '0.135', 'Minor salivary gland ductal cells': '-0.306', 'Minor salivary gland basal cells': '0.707', 'Mitotic cells (Minor salivary gland)': '0.960', 'Adipocytes (Minor salivary gland)': '0.178', 'Somatotropes': '-0.278', 'Lactotropes': '-0.266', 'Gonadotropes': '-0.121', 'Corticotropes': '-0.139', 'Thyrotropes': '0.016', 'Undifferentiated cells (Pituitary gland)': '0.401', 'Mitotic cells (Spleen)': '0.955', 'Platelets': '0.146', 'Erythrocytes': '0.343', 'Hematopoietic stem cells': '0.427', 'B-cells (Spleen)': '-0.137', 'NK-cells (Spleen)': '-0.204', 'Amygdala excitatory': '0.1', 'Cerebellar inhibitory': '0.0', 'Cge interneuron': '0.0', 'Deep-layer corticothalamic and 6b': '0.0', 'Deep-layer intratelencephalic': '0.0', 'Deep-layer near-projecting': '0.0', 'Eccentric medium spiny neuron': '0.1', 'Hippocampal ca1-3': '0.1', 'Hippocampal ca4': '0.0', 'Hippocampal dentate gyrus': '0.2', 'Lamp5-lhx6 and chandelier': '0.1', 'Lower rhombic lip': '0.0', 'Mammillary body': '0.0', 'Medium spiny neuron': '0.1', 'Mge interneuron': '0.0', 'Midbrain-derived inhibitory': '0.1', 'Miscellaneous': '0.0', 'Splatter': '0.1', 'Thalamic excitatory': '0.0', 'Upper rhombic lip': '0.0', 'Upper-layer intratelencephalic': '0.0', 'Astrocyte': '0.3', 'Bergmann glia': '0.5', 'Central nervous system macrophage': '0.3', 'Choroid plexus epithelial cell': '0.1', 'Committed oligodendrocyte precursor': '0.0', 'Ependymal cell': '0.2', 'Oligodendrocyte': '0.1', 'Oligodendrocyte precursor cell': '0.1', 'Endothelial cell': '0.3', 'Pericyte': '0.0', 'Vascular associated smooth muscle cell': '0.0', 'Fibroblast': '0.0', 'Leukocyte': '0.0', 'Basophil': '2.2', 'Eosinophil': '0.5', 'Neutrophil': '0.2', 'Classical monocyte': '4.8', 'Non-classical monocyte': '4.5', 'Intermediate monocyte': '1.7', 'T-reg': '7.8', 'GdT-cell': '0.1', 'MAIT T-cell': '0.4', 'Memory CD4 T-cell': '0.6', 'Naive CD4 T-cell': '2.1', 'Memory CD8 T-cell': '0.5', 'Naive CD8 T-cell': '1.8', 'Memory B-cell': '0.3', 'Naive B-cell': '7.3', 'Plasmacytoid DC': '2.9', 'Myeloid DC': '1.1', 'NK-cell': '6.1', 'Total PBMC': '4.8', 'Vd2 gdTCR': '0.6', 'Memory CD4 T-cell Th1\\/Th17': '2.9', 'Memory CD4 T-cell Th17': '8.3', 'Memory CD4 T-cell Th2': '9.8', 'Non-Vd2 gdTCR': '1.0', 'Memory CD4 T-cell Th1': '6.3', 'Memory CD4 T-cell TFH': '5.6', 'Terminal effector memory CD4 T-cell': '0.1', 'Central memory CD8 T-cell': '1.7', 'Effector memory CD8 T-cell': '8.4', 'Terminal effector memory CD8 T-cell': '1.2', 'Non-switched memory B-cell': '0.5', 'Plasmablast': '66.2', 'Switched memory 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91.22, 89.78, 85.98, 86.1, 84.65, 80.28, 77.38, 68.63, 68.39, 65.34, 59.2, 60.48, 53.12, 53.53, 54.01, 54.54, 56.89, 53.84, 59.23, 59.83, 60.83, 63.51, 63.62, 60.49, 62.1, 67.72, 65.62, 66.66, 72.16, 74.51, 73.66, 72.38, 69.59, 73.9, 80.05, 83.45, 88.14, 86.69, 88.69, 89.83, 92.71, 93.89, 92.98, 93.38, 95.03, 95.62, 94.77, 95.43, 95.27, 92.44, 93.56, 95.06, 91.95, 91.41, 91.33, 90.97, 91.19, 87.79, 89.59, 92.13, 85.98, 75.74, 71.07, 63.04, 52.59, 56.93, 37.14] | [0.79, 0.91, 0.53, 0.18, 0.44, 0.4, 0.8, 0.49, 0.0, 0.56, 0.81, 0.32, 0.73, 0.4, 0.53, 0.41, 0.02, 0.26, 0.54, 0.1, 0.0, 0.62, 0.42, 0.22, 0.81, 0.29, 0.66, 0.13, 0.73, 0.27, 0.81, 0.37, 0.74, 0.64, 0.0, 0.22, 0.78, 0.39, 0.01, 0.27, 0.44, 0.28, 0.19, 0.59, 0.56, 0.47, 0.57, 0.78, 0.55, 0.66, 0.82, 0.87, 0.74, 0.98, 0.96, 0.98, 1.0, 0.96, 1.0, 1.0, 1.0, 1.0, 0.99, 1.0, 0.93, 1.0, 0.76, 0.91, 0.74, 0.87, 0.83, 0.84, 0.9, 0.95, 1.0, 0.99, 1.0, 1.0, 0.93, 0.99, 0.84, 0.99, 0.97, 1.0, 0.95, 1.0, 0.95, 0.98, 0.91, 0.94, 0.99, 0.75, 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1.0, 0.98, 1.0, 0.95, 1.0, 0.93, 0.93, 0.78, 0.94, 0.8, 0.88, 0.77, 0.93, 0.82, 0.8, 0.61, 0.88, 0.86, 0.65, 0.96, 0.88, 0.68, 1.0, 0.81, 0.57, 0.77, 0.85, 0.76, 0.86, 0.88, 0.74, 0.85, 0.78, 0.83, 0.86, 0.84, 0.95, 0.95, 0.76, 0.88, 0.83, 0.8, 0.8, 0.84, 0.81, 0.97, 0.85, 0.98, 0.92, 0.98, 0.93, 0.94, 0.97, 0.9, 0.98, 0.86, 0.94, 0.86, 0.97, 0.83, 0.97, 0.86, 0.93, 0.9, 0.95, 1.0, 0.95, 0.99, 0.82, 0.82, 0.93, 0.49, 0.96, 0.95, 0.7, 0.9, 0.71, 0.86, 0.74, 0.85, 0.76, 0.91, 0.78, 0.81, 0.88, 0.59, 0.95, 0.82, 0.9, 0.94, 0.83, 0.74, 0.49, 0.54, 0.77, 0.45, 0.38, 0.7, 0.71, 0.76, 0.84, 0.62, 0.93, 0.69, 0.97, 0.58, 0.61, 0.91, 0.63, 0.95, 0.77, 0.95, 0.88, 0.93, 0.73, 0.94, 0.73, 0.86, 0.63, 0.6, 0.69, 0.65, 0.45, 0.63, 0.67, 0.47, 0.51, 0.53, 0.58, 0.38, 0.45, 0.63, 0.62, 0.7, 0.85, 0.42, 0.84, 0.98, 0.82, 0.79, 0.76, 0.82, 0.47, 0.6, 0.67, 0.56, 0.42, 0.48, 0.63, 0.59, 0.66, 0.62, 0.52, 0.61, 0.45, 0.69, 0.56, 0.68, 0.57, 0.67, 0.55, 0.7, 0.5, 0.42, 0.15, 0.65, 0.81, 0.73, 0.64, 0.63, 0.79, 0.83, 0.76, 0.86, 0.94] | null | Component of an E-cadherin/ catenin adhesion complex composed of at least E-cadherin/CDH1, beta-catenin/CTNNB1 or gamma-catenin/JUP, and potentially alpha-catenin/CTNNA1. Forms a ternary complex composed of ADAM10, CADH1 and EPHA4, | null | null | KLRG1, SPEF1, DLGAP5, AJAP1, RAPGEF2, RAB8B, PIP5K1C, PKP2, TRPV4, CTNNB1, CAV1, DDR1, TBC1D2, CTNNA1, JUP, CTNND1, PSEN1, LIMA1, CDH1, JUP, ADAM10, CADH1 , EPHA4, | null | null | null | null | Homodimer | null | 79.91949 | 0.474025 | 62.090499 | 0.79 | 1,804 |
P12830 | Q9BXS6-2 | null | degron_data | CDH1 | MGPWSRSLSALLLLLQVSSWLCQEPEPCHPGFDAESYTFTVPRRHLERGRVLGRVNFEDCTGRQRTAYFSLDTRFKVGTDGVITVKRPLRFHNPQIHFLVYAWDSTYRKFSTKVTLNTVGHHHRPPPHQASVSGIQAELLTFPNSSPGLRRQKRDWVIPPISCPENEKGPFPKNLVQIKSNKDKEGKVFYSITGQGADTPPVGVFIIERETGWLKVTEPLDRERIATYTLFSHAVSSNGNAVEDPMEILITVTDQNDNKPEFTQEVFKGSVMEGALPGTSVMEVTATDADDDVNTYNAAIAYTILSQDPELPDKNMFTINRNTGVISVVTTGLDRESFPTYTLVVQAADLQGEGLSTTATAVITVTDTNDNPPIFNPTTYKGQVPENEANVVITTLKVTDADAPNTPAWEAVYTILNDDGGQFVVTTNPVNNDGILKTAKGLDFEAKQQYILHVAVTNVVPFEVSLTTSTATVTVDVLDVNEAPIFVPPEKRVEVSEDFGVGQEITSYTAQEPDTFMEQKITYRIWRDTANWLEINPDTGAISTRAELDREDFEHVKNSTYTALIIATDNGSPVATGTGTLLLILSDVNDNAPIPEPRTIFFCERNPKPQVINIIDADLPPNTSPFTAELTHGASANWTIQYNDPTQESIILKPKMALEVGDYKINLKLMDNQNKDQVTTLEVSVCDCEGAAGVCRKAQPVEAGLQIPAILGILGGILALLILILLLLLFLRRRAVVKEPLLPPEDDTRDNVYYYDEEGGGEEDQDFDLSQLHRGLDARPEVTRNDVAPTLMSVPRYLPRPANPDEIGNFIDENLKAADTDPTAPPYDSLLVFDYEGSGSEAASLSSLNSSESDKDQDYDYLNEWGNRFKKLADMYGGGEDD | Homo sapiens | Cell junction, adherens junction, Cell membrane, Endosome, Golgi apparatus, trans-Golgi network, Cytoplasm, Cell junction, desmosome | Tissue enhanced (parathyroid) | {'Ciliated cells': '119.1', 'Basal respiratory cells': '71.1', 'Club cells': '97.3', 'Ionocytes': '81.0', 'Mucus glandular cells': '155.0', 'Serous glandular cells': '67.8', 'Gastric mucus-secreting cells': '133.2', 'Proximal enterocytes': '140.9', 'Paneth cells': '125.1', 'Distal enterocytes': '307.5', 'Intestinal goblet cells': '173.5', 'Exocrine glandular cells': '-0.605', 'Basal prostatic cells': '68.3', 'Prostatic glandular cells': '186.7', 'Breast glandular cells': '0.773', 'Breast myoepithelial cells': '0.700', 'Glandular and luminal cells': '313.0', 'Secretory cells': '82.3', 'Basal keratinocytes': '102.5', 'Suprabasal keratinocytes': '162.6', 'Basal squamous epithelial cells': '51.0', 'Squamous epithelial cells': '106.9', 'Alveolar cells type 1': '0.437', 'Alveolar cells type 2': '0.706', 'Salivary duct cells': '95.9', 'Ductal cells': '0.541', 'Hepatocytes': '0.600', 'Cholangiocytes': '129.7', 'Proximal tubular cells': '0.042', 'Distal tubular cells': '0.0', 'Collecting duct cells': '143.9', 'Mesothelial cells': '0.799', 'Sertoli cells': '0.252', 'Granulosa cells': '12.9', 'Enteroendocrine cells': '92.4', 'Pancreatic endocrine cells': '78.1', 'Leydig cells': '0.264', 'Excitatory neurons': '0.7', 'Inhibitory neurons': '1.3', 'Cone photoreceptor cells': '0.0', 'Rod photoreceptor cells': '0.0', 'Bipolar cells': '0.2', 'Horizontal cells': '0.6', 'Astrocytes': '0.6', 'Oligodendrocyte precursor cells': '0.5', 'Oligodendrocytes': '29.9', 'Microglial cells': '0.9', 'Muller glia cells': '0.1', 'Schwann cells': '0.131', 'Spermatogonia': '0.392', 'Spermatocytes': '0.193', 'Early spermatids': '-0.217', 'Late spermatids': '-0.290', 'Oocytes': '16.9', 'Cytotrophoblasts': '119.2', 'Syncytiotrophoblasts': '45.0', 'Extravillous trophoblasts': '24.9', 'Endothelial cells': '6.1', 'Lymphatic endothelial cells': '0.4', 'Cardiomyocytes': '0.135', 'Skeletal myocytes': '0.107', 'Smooth muscle cells': '5.8', 'Adipocytes': '2.1', 'Melanocytes': '0.335', 'Fibroblasts': '6.5', 'Peritubular cells': '0.210', 'Endometrial stromal cells': '27.7', 'Ovarian stromal cells': '0.7', 'Undifferentiated cells': '101.6', 'T-cells': '2.9', 'B-cells': '4.4', 'Plasma cells': '6.1', 'Nk-cells': '0.0', 'Granulocytes': '8.4', 'Monocytes': '0.0', 'Macrophages': '6.0', 'Hofbauer cells': '4.3', 'Kupffer cells': '1.0', 'Dendritic cells': '5.9', 'Langerhans cells': '0.304', 'Erythroid cells': '0.036', 'Adipocytes (Subcutaneous)': '-0.081', 'Adipocytes (Visceral)': '-0.209', 'Breast glandular cells (progenitors)': '0.538', 'Adipocytes (Breast)': '-0.689', 'Colon enterocytes': '0.790', 'Colon enteroendocrine cells': '0.112', 'Enteric glia cells': '-0.048', 'Mitotic cells (Colon)': '0.299', 'Mitotic cells (Heart)': '0.120', 'Podocytes': '-0.118', 'Ascending Loop of Henle cells': '0.475', 'Intercalated cells': '0.212', 'Cholangiocyte': '0.090', 'NK-cells (Liver)': '-0.005', 'Respiratory ciliated cells': '-0.012', 'Mitotic cells (Lung)': '0.071', 'NK-cells (Lung)': '-0.266', 'B-cells (Lung)': '-0.296', 'Alpha cells': '0.270', 'Beta cells': '0.152', 'Prostate glandular cells': '0.764', 'Prostate basal glandular cells': '0.540', 'Urothelial cells': '0.205', 'Keratinocyte (other)': '0.510', 'Keratinocyte (granular)': '0.055', 'Hair cortex cells': '0.080', 'Inner root sheath cells': '0.131', 'Outer root sheath cells': '0.175', 'Sebaceous gland cells': '0.156', 'Eccrine sweat gland cells': '-0.207', 'Adipocytes (Skin)': '-0.244', 'Mitotic cells (Skin)': '0.442', 'Parietal cells': '0.654', 'Chief cells': '0.649', 'Gastric mucous cells': '0.781', 'Gastric enteroendocrine cells': '0.590', 'Mitotic cells (Stomach)': '0.445', 'Parafollicular cells': '0.173', 'Thyroid glandular cells': '0.865', 'Mitotic cells (Thyroid)': '-0.081', 'Adrenal cortex cells': '0.051', 'Adrenal medulla cells': '0.087', 'Mitotic cells (Adrenal gland)': '0.072', 'Minor salivary glandular cells': '0.371', 'Minor salivary gland ductal cells': '-0.142', 'Minor salivary gland basal cells': '0.582', 'Mitotic cells (Minor salivary gland)': '0.567', 'Adipocytes (Minor salivary gland)': '0.050', 'Somatotropes': '0.121', 'Lactotropes': '0.322', 'Gonadotropes': '0.330', 'Corticotropes': '0.180', 'Thyrotropes': '0.496', 'Undifferentiated cells (Pituitary gland)': '-0.108', 'Mitotic cells (Spleen)': '-0.228', 'Platelets': '-0.050', 'Erythrocytes': '-0.158', 'Hematopoietic stem cells': '-0.211', 'B-cells (Spleen)': '0.266', 'NK-cells (Spleen)': '0.309', 'Amygdala excitatory': '1.0', 'Cerebellar inhibitory': '0.9', 'Cge interneuron': '0.7', 'Deep-layer corticothalamic and 6b': '1.5', 'Deep-layer intratelencephalic': '0.7', 'Deep-layer near-projecting': '0.7', 'Eccentric medium spiny neuron': '0.6', 'Hippocampal ca1-3': '1.9', 'Hippocampal ca4': '1.2', 'Hippocampal dentate gyrus': '1.1', 'Lamp5-lhx6 and chandelier': '0.5', 'Lower rhombic lip': '0.8', 'Mammillary body': '0.6', 'Medium spiny neuron': '0.7', 'Mge interneuron': '1.7', 'Midbrain-derived inhibitory': '0.7', 'Miscellaneous': '0.9', 'Splatter': '3.8', 'Thalamic excitatory': '0.5', 'Upper rhombic lip': '0.8', 'Upper-layer intratelencephalic': '0.6', 'Astrocyte': '4.4', 'Bergmann glia': '0.2', 'Central nervous system macrophage': '0.6', 'Choroid plexus epithelial cell': '52.1', 'Committed oligodendrocyte precursor': '41.5', 'Ependymal cell': '4.8', 'Oligodendrocyte': '53.1', 'Oligodendrocyte precursor cell': '2.4', 'Endothelial cell': '0.7', 'Pericyte': '0.3', 'Vascular associated smooth muscle cell': '0.0', 'Fibroblast': '17.4', 'Leukocyte': '1.1', 'Basophil': '0.0', 'Eosinophil': '0.0', 'Neutrophil': '0.0', 'Classical monocyte': '0.0', 'Non-classical monocyte': '0.0', 'Intermediate monocyte': '0.0', 'T-reg': '2.3', 'GdT-cell': '0.0', 'MAIT T-cell': '0.0', 'Memory CD4 T-cell': '0.0', 'Naive CD4 T-cell': '0.1', 'Memory CD8 T-cell': '0.2', 'Naive CD8 T-cell': '0.3', 'Memory B-cell': '0.0', 'Naive B-cell': '0.1', 'Plasmacytoid DC': '46.6', 'Myeloid DC': '8.5', 'NK-cell': '0.1', 'Total PBMC': '0.7', 'Vd2 gdTCR': '0.0', 'Memory CD4 T-cell Th1\\/Th17': '0.1', 'Memory CD4 T-cell Th17': '0.2', 'Memory CD4 T-cell Th2': '2.9', 'Non-Vd2 gdTCR': '0.1', 'Memory CD4 T-cell Th1': '0.3', 'Memory CD4 T-cell TFH': '0.5', 'Terminal effector memory CD4 T-cell': '0.0', 'Central memory CD8 T-cell': '4.8', 'Effector memory CD8 T-cell': '0.0', 'Terminal effector memory CD8 T-cell': '0.6', 'Non-switched memory B-cell': '0.0', 'Plasmablast': '3.3', 'Switched memory B-cell': '0.0', 'Exhausted memory B-cell': '0.7', 'Progenitor cell': '2.3', 'Memory T-reg': '1.3', 'Naive CD4 T-cell activated': '0.3', 'Naive CD8 T-cell activated': '0.6', 'Naive T-reg': '0.1'} | 1O6S, 2O72, 2OMT, 2OMU, 2OMV, 2OMX, 2OMY, 2OMZ, 3FF7, 3FF8, 3L6X, 3L6Y, 4ZT1, 4ZTE, 6CXY, 6OLE, 6OLF, 6OLG, 6VEL, 7STZ, 8H62 | {'Adipose Tissue': 1.2125261088039867, 'Adrenal Gland': 0.1914223992248062, 'Bladder': 39.2033519047619, 'Blood': 1.340954264800861, 'Blood Vessel': 0.3121561692883895, 'Brain': 0.8550442199091597, 'Breast': 38.54918344226579, 'Cervix Uteri': 23.539115789473684, 'Colon': 43.41292142490372, 'Esophagus': 53.97513367404844, 'Fallopian Tube': 14.900277777777776, 'Heart': 0.119140469221835, 'Kidney': 25.040449438202245, 'Liver': 26.60802654867257, 'Lung': 35.447986366782004, 'Muscle': 0.1378936151930261, 'Nerve': 17.518468982229404, 'Ovary': 3.6515122222222223, 'Pancreas': 56.89676829268293, 'Pituitary': 24.68741660777385, 'Prostate': 61.279967346938776, 'Salivary Gland': 92.01685185185184, 'Skin': 79.77571720232172, 'Small Intestine': 71.7519320855615, 'Spleen': 10.061029045643156, 'Stomach': 58.07813805013927, 'Testis': 0.8144204986149585, 'Thyroid': 135.176797856049, 'Uterus': 1.442593943661972, 'Vagina': 86.52345512820513} | NUSAP1 | MIIPSLEELDSLKYSDLQNLAKSLGLRANLRATKLLKALKGYIKHEARKGNENQDESQTSASSCDETEIQISNQEEAERQPLGHVTKTRRRCKTVRVDPDSQQNHSEIKISNPTEFQNHEKQESQDLRATAKVPSPPDEHQEAENAVSSGNRDSKVPSEGKKSLYTDESSKPGKNKRTAITTPNFKKLHEAHFKEMESIDQYIERKKKHFEEHNSMNELKQPINKGGVRTPVPPRGRLSVASTPISQRRSQGRSCGPASQSTLGLKGSLKRSAISAAKTGVRFSAATKDNEHKRSLTKTPARKSAHVTVSGGTPKGEAVLGTHKLKTITGNSAAVITPFKLTTEATQTPVSNKKPVFDLKASLSRPLNYEPHKGKLKPWGQSKENNYLNQHVNRINFYKKTYKQPHLQTKEEQRKKREQERKEKKAKVLGMRRGLILAED | Homo sapiens | null | Not found | {} | null | {'Adipose Tissue': 3.0626249169435216, 'Adrenal Gland': 20.066418604651165, 'Bladder': 2.5714285714285716, 'Blood': 38.67838557588806, 'Blood Vessel': 1.907438127340824, 'Brain': 0.921281385314156, 'Breast': 2.6828954248366013, 'Cervix Uteri': 4.126584210526316, 'Colon': 5.369006418485237, 'Esophagus': 10.88004830449827, 'Fallopian Tube': 2.6983444444444444, 'Heart': 0.9591686178861788, 'Kidney': 2.958684269662921, 'Liver': 3.8981778761061943, 'Lung': 8.120652249134949, 'Muscle': 4.355879825653798, 'Nerve': 2.3376048465266557, 'Ovary': 9.89653888888889, 'Pancreas': 1.0126895426829268, 'Pituitary': 1.4382194346289752, 'Prostate': 2.505309795918367, 'Salivary Gland': 5.667204320987654, 'Skin': 27.983096738529575, 'Small Intestine': 12.297466310160427, 'Spleen': 13.0189377593361, 'Stomach': 6.007349025069638, 'Testis': 25.17539335180055, 'Thyroid': 2.2111070444104137, 'Uterus': 2.285015492957746, 'Vagina': 12.095448076923075} | [39.93, 46.46, 52.9, 44.21, 41.4, 39.93, 35.91, 38.61, 36.44, 36.25, 34.86, 32.82, 32.01, 32.75, 31.69, 35.64, 36.35, 34.66, 33.32, 32.71, 35.01, 30.17, 37.05, 36.53, 48.19, 58.22, 64.94, 73.22, 78.33, 82.63, 85.79, 89.39, 87.89, 85.58, 83.93, 89.1, 89.27, 90.66, 87.86, 86.2, 82.97, 72.75, 73.3, 76.44, 82.38, 82.41, 79.49, 86.6, 76.32, 85.48, 88.69, 84.35, 87.75, 90.57, 88.72, 89.46, 87.48, 85.3, 81.72, 79.46, 77.26, 69.01, 67.1, 62.83, 67.71, 74.96, 82.95, 86.74, 86.35, 86.49, 84.6, 85.99, 85.64, 87.19, 89.23, 89.3, 90.62, 84.21, 85.42, 83.34, 84.28, 89.8, 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Forms a ternary complex composed of ADAM10, CADH1 and EPHA4, | null | null | KLRG1, SPEF1, DLGAP5, AJAP1, RAPGEF2, RAB8B, PIP5K1C, PKP2, TRPV4, CTNNB1, CAV1, DDR1, TBC1D2, CTNNA1, JUP, CTNND1, PSEN1, LIMA1, CDH1, JUP, ADAM10, CADH1 , EPHA4, | null | null | null | null | Homodimer | null | 79.91949 | 0.474025 | null | null | 1,804 |
P12830 | Q9BXS6-5 | null | degron_data | CDH1 | MGPWSRSLSALLLLLQVSSWLCQEPEPCHPGFDAESYTFTVPRRHLERGRVLGRVNFEDCTGRQRTAYFSLDTRFKVGTDGVITVKRPLRFHNPQIHFLVYAWDSTYRKFSTKVTLNTVGHHHRPPPHQASVSGIQAELLTFPNSSPGLRRQKRDWVIPPISCPENEKGPFPKNLVQIKSNKDKEGKVFYSITGQGADTPPVGVFIIERETGWLKVTEPLDRERIATYTLFSHAVSSNGNAVEDPMEILITVTDQNDNKPEFTQEVFKGSVMEGALPGTSVMEVTATDADDDVNTYNAAIAYTILSQDPELPDKNMFTINRNTGVISVVTTGLDRESFPTYTLVVQAADLQGEGLSTTATAVITVTDTNDNPPIFNPTTYKGQVPENEANVVITTLKVTDADAPNTPAWEAVYTILNDDGGQFVVTTNPVNNDGILKTAKGLDFEAKQQYILHVAVTNVVPFEVSLTTSTATVTVDVLDVNEAPIFVPPEKRVEVSEDFGVGQEITSYTAQEPDTFMEQKITYRIWRDTANWLEINPDTGAISTRAELDREDFEHVKNSTYTALIIATDNGSPVATGTGTLLLILSDVNDNAPIPEPRTIFFCERNPKPQVINIIDADLPPNTSPFTAELTHGASANWTIQYNDPTQESIILKPKMALEVGDYKINLKLMDNQNKDQVTTLEVSVCDCEGAAGVCRKAQPVEAGLQIPAILGILGGILALLILILLLLLFLRRRAVVKEPLLPPEDDTRDNVYYYDEEGGGEEDQDFDLSQLHRGLDARPEVTRNDVAPTLMSVPRYLPRPANPDEIGNFIDENLKAADTDPTAPPYDSLLVFDYEGSGSEAASLSSLNSSESDKDQDYDYLNEWGNRFKKLADMYGGGEDD | Homo sapiens | Cell junction, adherens junction, Cell membrane, Endosome, Golgi apparatus, trans-Golgi network, Cytoplasm, Cell junction, desmosome | Tissue enhanced (parathyroid) | {'Ciliated cells': '119.1', 'Basal respiratory cells': '71.1', 'Club cells': '97.3', 'Ionocytes': '81.0', 'Mucus glandular cells': '155.0', 'Serous glandular cells': '67.8', 'Gastric mucus-secreting cells': '133.2', 'Proximal enterocytes': '140.9', 'Paneth cells': '125.1', 'Distal enterocytes': '307.5', 'Intestinal goblet cells': '173.5', 'Exocrine glandular cells': '-0.605', 'Basal prostatic cells': '68.3', 'Prostatic glandular cells': '186.7', 'Breast glandular cells': '0.773', 'Breast myoepithelial cells': '0.700', 'Glandular and luminal cells': '313.0', 'Secretory cells': '82.3', 'Basal keratinocytes': '102.5', 'Suprabasal keratinocytes': '162.6', 'Basal squamous epithelial cells': '51.0', 'Squamous epithelial cells': '106.9', 'Alveolar cells type 1': '0.437', 'Alveolar cells type 2': '0.706', 'Salivary duct cells': '95.9', 'Ductal cells': '0.541', 'Hepatocytes': '0.600', 'Cholangiocytes': '129.7', 'Proximal tubular cells': '0.042', 'Distal tubular cells': '0.0', 'Collecting duct cells': '143.9', 'Mesothelial cells': '0.799', 'Sertoli cells': '0.252', 'Granulosa cells': '12.9', 'Enteroendocrine cells': '92.4', 'Pancreatic endocrine cells': '78.1', 'Leydig cells': '0.264', 'Excitatory neurons': '0.7', 'Inhibitory neurons': '1.3', 'Cone photoreceptor cells': '0.0', 'Rod photoreceptor cells': '0.0', 'Bipolar cells': '0.2', 'Horizontal cells': '0.6', 'Astrocytes': '0.6', 'Oligodendrocyte precursor cells': '0.5', 'Oligodendrocytes': '29.9', 'Microglial cells': '0.9', 'Muller glia cells': '0.1', 'Schwann cells': '0.131', 'Spermatogonia': '0.392', 'Spermatocytes': '0.193', 'Early spermatids': '-0.217', 'Late spermatids': '-0.290', 'Oocytes': '16.9', 'Cytotrophoblasts': '119.2', 'Syncytiotrophoblasts': '45.0', 'Extravillous trophoblasts': '24.9', 'Endothelial cells': '6.1', 'Lymphatic endothelial cells': '0.4', 'Cardiomyocytes': '0.135', 'Skeletal myocytes': '0.107', 'Smooth muscle cells': '5.8', 'Adipocytes': '2.1', 'Melanocytes': '0.335', 'Fibroblasts': '6.5', 'Peritubular cells': '0.210', 'Endometrial stromal cells': '27.7', 'Ovarian stromal cells': '0.7', 'Undifferentiated cells': '101.6', 'T-cells': '2.9', 'B-cells': '4.4', 'Plasma cells': '6.1', 'Nk-cells': '0.0', 'Granulocytes': '8.4', 'Monocytes': '0.0', 'Macrophages': '6.0', 'Hofbauer cells': '4.3', 'Kupffer cells': '1.0', 'Dendritic cells': '5.9', 'Langerhans cells': '0.304', 'Erythroid cells': '0.036', 'Adipocytes (Subcutaneous)': '-0.081', 'Adipocytes (Visceral)': '-0.209', 'Breast glandular cells (progenitors)': '0.538', 'Adipocytes (Breast)': '-0.689', 'Colon enterocytes': '0.790', 'Colon enteroendocrine cells': '0.112', 'Enteric glia cells': '-0.048', 'Mitotic cells (Colon)': '0.299', 'Mitotic cells (Heart)': '0.120', 'Podocytes': '-0.118', 'Ascending Loop of Henle cells': '0.475', 'Intercalated cells': '0.212', 'Cholangiocyte': '0.090', 'NK-cells (Liver)': '-0.005', 'Respiratory ciliated cells': '-0.012', 'Mitotic cells (Lung)': '0.071', 'NK-cells (Lung)': '-0.266', 'B-cells (Lung)': '-0.296', 'Alpha cells': '0.270', 'Beta cells': '0.152', 'Prostate glandular cells': '0.764', 'Prostate basal glandular cells': '0.540', 'Urothelial cells': '0.205', 'Keratinocyte (other)': '0.510', 'Keratinocyte (granular)': '0.055', 'Hair cortex cells': '0.080', 'Inner root sheath cells': '0.131', 'Outer root sheath cells': '0.175', 'Sebaceous gland cells': '0.156', 'Eccrine sweat gland cells': '-0.207', 'Adipocytes (Skin)': '-0.244', 'Mitotic cells (Skin)': '0.442', 'Parietal cells': '0.654', 'Chief cells': '0.649', 'Gastric mucous cells': '0.781', 'Gastric enteroendocrine cells': '0.590', 'Mitotic cells (Stomach)': '0.445', 'Parafollicular cells': '0.173', 'Thyroid glandular cells': '0.865', 'Mitotic cells (Thyroid)': '-0.081', 'Adrenal cortex cells': '0.051', 'Adrenal medulla cells': '0.087', 'Mitotic cells (Adrenal gland)': '0.072', 'Minor salivary glandular cells': '0.371', 'Minor salivary gland ductal cells': '-0.142', 'Minor salivary gland basal cells': '0.582', 'Mitotic cells (Minor salivary gland)': '0.567', 'Adipocytes (Minor salivary gland)': '0.050', 'Somatotropes': '0.121', 'Lactotropes': '0.322', 'Gonadotropes': '0.330', 'Corticotropes': '0.180', 'Thyrotropes': '0.496', 'Undifferentiated cells (Pituitary gland)': '-0.108', 'Mitotic cells (Spleen)': '-0.228', 'Platelets': '-0.050', 'Erythrocytes': '-0.158', 'Hematopoietic stem cells': '-0.211', 'B-cells (Spleen)': '0.266', 'NK-cells (Spleen)': '0.309', 'Amygdala excitatory': '1.0', 'Cerebellar inhibitory': '0.9', 'Cge interneuron': '0.7', 'Deep-layer corticothalamic and 6b': '1.5', 'Deep-layer intratelencephalic': '0.7', 'Deep-layer near-projecting': '0.7', 'Eccentric medium spiny neuron': '0.6', 'Hippocampal ca1-3': '1.9', 'Hippocampal ca4': '1.2', 'Hippocampal dentate gyrus': '1.1', 'Lamp5-lhx6 and chandelier': '0.5', 'Lower rhombic lip': '0.8', 'Mammillary body': '0.6', 'Medium spiny neuron': '0.7', 'Mge interneuron': '1.7', 'Midbrain-derived inhibitory': '0.7', 'Miscellaneous': '0.9', 'Splatter': '3.8', 'Thalamic excitatory': '0.5', 'Upper rhombic lip': '0.8', 'Upper-layer intratelencephalic': '0.6', 'Astrocyte': '4.4', 'Bergmann glia': '0.2', 'Central nervous system macrophage': '0.6', 'Choroid plexus epithelial cell': '52.1', 'Committed oligodendrocyte precursor': '41.5', 'Ependymal cell': '4.8', 'Oligodendrocyte': '53.1', 'Oligodendrocyte precursor cell': '2.4', 'Endothelial cell': '0.7', 'Pericyte': '0.3', 'Vascular associated smooth muscle cell': '0.0', 'Fibroblast': '17.4', 'Leukocyte': '1.1', 'Basophil': '0.0', 'Eosinophil': '0.0', 'Neutrophil': '0.0', 'Classical monocyte': '0.0', 'Non-classical monocyte': '0.0', 'Intermediate monocyte': '0.0', 'T-reg': '2.3', 'GdT-cell': '0.0', 'MAIT T-cell': '0.0', 'Memory CD4 T-cell': '0.0', 'Naive CD4 T-cell': '0.1', 'Memory CD8 T-cell': '0.2', 'Naive CD8 T-cell': '0.3', 'Memory B-cell': '0.0', 'Naive B-cell': '0.1', 'Plasmacytoid DC': '46.6', 'Myeloid DC': '8.5', 'NK-cell': '0.1', 'Total PBMC': '0.7', 'Vd2 gdTCR': '0.0', 'Memory CD4 T-cell Th1\\/Th17': '0.1', 'Memory CD4 T-cell Th17': '0.2', 'Memory CD4 T-cell Th2': '2.9', 'Non-Vd2 gdTCR': '0.1', 'Memory CD4 T-cell Th1': '0.3', 'Memory CD4 T-cell TFH': '0.5', 'Terminal effector memory CD4 T-cell': '0.0', 'Central memory CD8 T-cell': '4.8', 'Effector memory CD8 T-cell': '0.0', 'Terminal effector memory CD8 T-cell': '0.6', 'Non-switched memory B-cell': '0.0', 'Plasmablast': '3.3', 'Switched memory B-cell': '0.0', 'Exhausted memory B-cell': '0.7', 'Progenitor cell': '2.3', 'Memory T-reg': '1.3', 'Naive CD4 T-cell activated': '0.3', 'Naive CD8 T-cell activated': '0.6', 'Naive T-reg': '0.1'} | 1O6S, 2O72, 2OMT, 2OMU, 2OMV, 2OMX, 2OMY, 2OMZ, 3FF7, 3FF8, 3L6X, 3L6Y, 4ZT1, 4ZTE, 6CXY, 6OLE, 6OLF, 6OLG, 6VEL, 7STZ, 8H62 | {'Adipose Tissue': 1.2125261088039867, 'Adrenal Gland': 0.1914223992248062, 'Bladder': 39.2033519047619, 'Blood': 1.340954264800861, 'Blood Vessel': 0.3121561692883895, 'Brain': 0.8550442199091597, 'Breast': 38.54918344226579, 'Cervix Uteri': 23.539115789473684, 'Colon': 43.41292142490372, 'Esophagus': 53.97513367404844, 'Fallopian Tube': 14.900277777777776, 'Heart': 0.119140469221835, 'Kidney': 25.040449438202245, 'Liver': 26.60802654867257, 'Lung': 35.447986366782004, 'Muscle': 0.1378936151930261, 'Nerve': 17.518468982229404, 'Ovary': 3.6515122222222223, 'Pancreas': 56.89676829268293, 'Pituitary': 24.68741660777385, 'Prostate': 61.279967346938776, 'Salivary Gland': 92.01685185185184, 'Skin': 79.77571720232172, 'Small Intestine': 71.7519320855615, 'Spleen': 10.061029045643156, 'Stomach': 58.07813805013927, 'Testis': 0.8144204986149585, 'Thyroid': 135.176797856049, 'Uterus': 1.442593943661972, 'Vagina': 86.52345512820513} | NUSAP1 | MIIPSLEELDSLKYSDLQNLAKSLGLRANLRATKLLKALKGYIKHEARKGNENQDESQTSASSCDETEIQISNQEEAERQPLGHVTKTRRRCKTVRVDPDSQNHSEIKISNPTEFQNHEKQESQDLRATAKVPSPPDEHQEAENAVSSGNRDSKVPSEGKKSLYTDESSKPGKNKRTAITTPNFKKLHEAHFKEMESIDQYIERKKKHFEEHNSMNELKQQPINKGGVRTPVPPRGRLSVASTPISQRRSQGRSCGPASQSTLGLKGSLKRSAISAAKTGVRFSAATKDNEHKRSLTKTPARKSAHVTVSGGTPKGEAVLGTHKLKTITGNSAAVITPFKLTTEATQTPVSNKKPVFDLKASLSRPLNYEPHKGKLKPWGQSKENNYLNQHVNRINFYKKTYKQPHLQTKEEQRKKREQERKEKKAKVLGMRRGLILAED | Homo sapiens | null | Not found | {} | null | {'Adipose Tissue': 3.0626249169435216, 'Adrenal Gland': 20.066418604651165, 'Bladder': 2.5714285714285716, 'Blood': 38.67838557588806, 'Blood Vessel': 1.907438127340824, 'Brain': 0.921281385314156, 'Breast': 2.6828954248366013, 'Cervix Uteri': 4.126584210526316, 'Colon': 5.369006418485237, 'Esophagus': 10.88004830449827, 'Fallopian Tube': 2.6983444444444444, 'Heart': 0.9591686178861788, 'Kidney': 2.958684269662921, 'Liver': 3.8981778761061943, 'Lung': 8.120652249134949, 'Muscle': 4.355879825653798, 'Nerve': 2.3376048465266557, 'Ovary': 9.89653888888889, 'Pancreas': 1.0126895426829268, 'Pituitary': 1.4382194346289752, 'Prostate': 2.505309795918367, 'Salivary Gland': 5.667204320987654, 'Skin': 27.983096738529575, 'Small Intestine': 12.297466310160427, 'Spleen': 13.0189377593361, 'Stomach': 6.007349025069638, 'Testis': 25.17539335180055, 'Thyroid': 2.2111070444104137, 'Uterus': 2.285015492957746, 'Vagina': 12.095448076923075} | [39.93, 46.46, 52.9, 44.21, 41.4, 39.93, 35.91, 38.61, 36.44, 36.25, 34.86, 32.82, 32.01, 32.75, 31.69, 35.64, 36.35, 34.66, 33.32, 32.71, 35.01, 30.17, 37.05, 36.53, 48.19, 58.22, 64.94, 73.22, 78.33, 82.63, 85.79, 89.39, 87.89, 85.58, 83.93, 89.1, 89.27, 90.66, 87.86, 86.2, 82.97, 72.75, 73.3, 76.44, 82.38, 82.41, 79.49, 86.6, 76.32, 85.48, 88.69, 84.35, 87.75, 90.57, 88.72, 89.46, 87.48, 85.3, 81.72, 79.46, 77.26, 69.01, 67.1, 62.83, 67.71, 74.96, 82.95, 86.74, 86.35, 86.49, 84.6, 85.99, 85.64, 87.19, 89.23, 89.3, 90.62, 84.21, 85.42, 83.34, 84.28, 89.8, 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Forms a ternary complex composed of ADAM10, CADH1 and EPHA4, | null | null | KLRG1, SPEF1, DLGAP5, AJAP1, RAPGEF2, RAB8B, PIP5K1C, PKP2, TRPV4, CTNNB1, CAV1, DDR1, TBC1D2, CTNNA1, JUP, CTNND1, PSEN1, LIMA1, CDH1, JUP, ADAM10, CADH1 , EPHA4, | null | null | null | null | Homodimer | null | 79.91949 | 0.474025 | null | null | 1,804 |
P12830 | Q9H467 | null | degron_data | CDH1 | MGPWSRSLSALLLLLQVSSWLCQEPEPCHPGFDAESYTFTVPRRHLERGRVLGRVNFEDCTGRQRTAYFSLDTRFKVGTDGVITVKRPLRFHNPQIHFLVYAWDSTYRKFSTKVTLNTVGHHHRPPPHQASVSGIQAELLTFPNSSPGLRRQKRDWVIPPISCPENEKGPFPKNLVQIKSNKDKEGKVFYSITGQGADTPPVGVFIIERETGWLKVTEPLDRERIATYTLFSHAVSSNGNAVEDPMEILITVTDQNDNKPEFTQEVFKGSVMEGALPGTSVMEVTATDADDDVNTYNAAIAYTILSQDPELPDKNMFTINRNTGVISVVTTGLDRESFPTYTLVVQAADLQGEGLSTTATAVITVTDTNDNPPIFNPTTYKGQVPENEANVVITTLKVTDADAPNTPAWEAVYTILNDDGGQFVVTTNPVNNDGILKTAKGLDFEAKQQYILHVAVTNVVPFEVSLTTSTATVTVDVLDVNEAPIFVPPEKRVEVSEDFGVGQEITSYTAQEPDTFMEQKITYRIWRDTANWLEINPDTGAISTRAELDREDFEHVKNSTYTALIIATDNGSPVATGTGTLLLILSDVNDNAPIPEPRTIFFCERNPKPQVINIIDADLPPNTSPFTAELTHGASANWTIQYNDPTQESIILKPKMALEVGDYKINLKLMDNQNKDQVTTLEVSVCDCEGAAGVCRKAQPVEAGLQIPAILGILGGILALLILILLLLLFLRRRAVVKEPLLPPEDDTRDNVYYYDEEGGGEEDQDFDLSQLHRGLDARPEVTRNDVAPTLMSVPRYLPRPANPDEIGNFIDENLKAADTDPTAPPYDSLLVFDYEGSGSEAASLSSLNSSESDKDQDYDYLNEWGNRFKKLADMYGGGEDD | Homo sapiens | Cell junction, adherens junction, Cell membrane, Endosome, Golgi apparatus, trans-Golgi network, Cytoplasm, Cell junction, desmosome | Tissue enhanced (parathyroid) | {'Ciliated cells': '119.1', 'Basal respiratory cells': '71.1', 'Club cells': '97.3', 'Ionocytes': '81.0', 'Mucus glandular cells': '155.0', 'Serous glandular cells': '67.8', 'Gastric mucus-secreting cells': '133.2', 'Proximal enterocytes': '140.9', 'Paneth cells': '125.1', 'Distal enterocytes': '307.5', 'Intestinal goblet cells': '173.5', 'Exocrine glandular cells': '-0.605', 'Basal prostatic cells': '68.3', 'Prostatic glandular cells': '186.7', 'Breast glandular cells': '0.773', 'Breast myoepithelial cells': '0.700', 'Glandular and luminal cells': '313.0', 'Secretory cells': '82.3', 'Basal keratinocytes': '102.5', 'Suprabasal keratinocytes': '162.6', 'Basal squamous epithelial cells': '51.0', 'Squamous epithelial cells': '106.9', 'Alveolar cells type 1': '0.437', 'Alveolar cells type 2': '0.706', 'Salivary duct cells': '95.9', 'Ductal cells': '0.541', 'Hepatocytes': '0.600', 'Cholangiocytes': '129.7', 'Proximal tubular cells': '0.042', 'Distal tubular cells': '0.0', 'Collecting duct cells': '143.9', 'Mesothelial cells': '0.799', 'Sertoli cells': '0.252', 'Granulosa cells': '12.9', 'Enteroendocrine cells': '92.4', 'Pancreatic endocrine cells': '78.1', 'Leydig cells': '0.264', 'Excitatory neurons': '0.7', 'Inhibitory neurons': '1.3', 'Cone photoreceptor cells': '0.0', 'Rod photoreceptor cells': '0.0', 'Bipolar cells': '0.2', 'Horizontal cells': '0.6', 'Astrocytes': '0.6', 'Oligodendrocyte precursor cells': '0.5', 'Oligodendrocytes': '29.9', 'Microglial cells': '0.9', 'Muller glia cells': '0.1', 'Schwann cells': '0.131', 'Spermatogonia': '0.392', 'Spermatocytes': '0.193', 'Early spermatids': '-0.217', 'Late spermatids': '-0.290', 'Oocytes': '16.9', 'Cytotrophoblasts': '119.2', 'Syncytiotrophoblasts': '45.0', 'Extravillous trophoblasts': '24.9', 'Endothelial cells': '6.1', 'Lymphatic endothelial cells': '0.4', 'Cardiomyocytes': '0.135', 'Skeletal myocytes': '0.107', 'Smooth muscle cells': '5.8', 'Adipocytes': '2.1', 'Melanocytes': '0.335', 'Fibroblasts': '6.5', 'Peritubular cells': '0.210', 'Endometrial stromal cells': '27.7', 'Ovarian stromal cells': '0.7', 'Undifferentiated cells': '101.6', 'T-cells': '2.9', 'B-cells': '4.4', 'Plasma cells': '6.1', 'Nk-cells': '0.0', 'Granulocytes': '8.4', 'Monocytes': '0.0', 'Macrophages': '6.0', 'Hofbauer cells': '4.3', 'Kupffer cells': '1.0', 'Dendritic cells': '5.9', 'Langerhans cells': '0.304', 'Erythroid cells': '0.036', 'Adipocytes (Subcutaneous)': '-0.081', 'Adipocytes (Visceral)': '-0.209', 'Breast glandular cells (progenitors)': '0.538', 'Adipocytes (Breast)': '-0.689', 'Colon enterocytes': '0.790', 'Colon enteroendocrine cells': '0.112', 'Enteric glia cells': '-0.048', 'Mitotic cells (Colon)': '0.299', 'Mitotic cells (Heart)': '0.120', 'Podocytes': '-0.118', 'Ascending Loop of Henle cells': '0.475', 'Intercalated cells': '0.212', 'Cholangiocyte': '0.090', 'NK-cells (Liver)': '-0.005', 'Respiratory ciliated cells': '-0.012', 'Mitotic cells (Lung)': '0.071', 'NK-cells (Lung)': '-0.266', 'B-cells (Lung)': '-0.296', 'Alpha cells': '0.270', 'Beta cells': '0.152', 'Prostate glandular cells': '0.764', 'Prostate basal glandular cells': '0.540', 'Urothelial cells': '0.205', 'Keratinocyte (other)': '0.510', 'Keratinocyte (granular)': '0.055', 'Hair cortex cells': '0.080', 'Inner root sheath cells': '0.131', 'Outer root sheath cells': '0.175', 'Sebaceous gland cells': '0.156', 'Eccrine sweat gland cells': '-0.207', 'Adipocytes (Skin)': '-0.244', 'Mitotic cells (Skin)': '0.442', 'Parietal cells': '0.654', 'Chief cells': '0.649', 'Gastric mucous cells': '0.781', 'Gastric enteroendocrine cells': '0.590', 'Mitotic cells (Stomach)': '0.445', 'Parafollicular cells': '0.173', 'Thyroid glandular cells': '0.865', 'Mitotic cells (Thyroid)': '-0.081', 'Adrenal cortex cells': '0.051', 'Adrenal medulla cells': '0.087', 'Mitotic cells (Adrenal gland)': '0.072', 'Minor salivary glandular cells': '0.371', 'Minor salivary gland ductal cells': '-0.142', 'Minor salivary gland basal cells': '0.582', 'Mitotic cells (Minor salivary gland)': '0.567', 'Adipocytes (Minor salivary gland)': '0.050', 'Somatotropes': '0.121', 'Lactotropes': '0.322', 'Gonadotropes': '0.330', 'Corticotropes': '0.180', 'Thyrotropes': '0.496', 'Undifferentiated cells (Pituitary gland)': '-0.108', 'Mitotic cells (Spleen)': '-0.228', 'Platelets': '-0.050', 'Erythrocytes': '-0.158', 'Hematopoietic stem cells': '-0.211', 'B-cells (Spleen)': '0.266', 'NK-cells (Spleen)': '0.309', 'Amygdala excitatory': '1.0', 'Cerebellar inhibitory': '0.9', 'Cge interneuron': '0.7', 'Deep-layer corticothalamic and 6b': '1.5', 'Deep-layer intratelencephalic': '0.7', 'Deep-layer near-projecting': '0.7', 'Eccentric medium spiny neuron': '0.6', 'Hippocampal ca1-3': '1.9', 'Hippocampal ca4': '1.2', 'Hippocampal dentate gyrus': '1.1', 'Lamp5-lhx6 and chandelier': '0.5', 'Lower rhombic lip': '0.8', 'Mammillary body': '0.6', 'Medium spiny neuron': '0.7', 'Mge interneuron': '1.7', 'Midbrain-derived inhibitory': '0.7', 'Miscellaneous': '0.9', 'Splatter': '3.8', 'Thalamic excitatory': '0.5', 'Upper rhombic lip': '0.8', 'Upper-layer intratelencephalic': '0.6', 'Astrocyte': '4.4', 'Bergmann glia': '0.2', 'Central nervous system macrophage': '0.6', 'Choroid plexus epithelial cell': '52.1', 'Committed oligodendrocyte precursor': '41.5', 'Ependymal cell': '4.8', 'Oligodendrocyte': '53.1', 'Oligodendrocyte precursor cell': '2.4', 'Endothelial cell': '0.7', 'Pericyte': '0.3', 'Vascular associated smooth muscle cell': '0.0', 'Fibroblast': '17.4', 'Leukocyte': '1.1', 'Basophil': '0.0', 'Eosinophil': '0.0', 'Neutrophil': '0.0', 'Classical monocyte': '0.0', 'Non-classical monocyte': '0.0', 'Intermediate monocyte': '0.0', 'T-reg': '2.3', 'GdT-cell': '0.0', 'MAIT T-cell': '0.0', 'Memory CD4 T-cell': '0.0', 'Naive CD4 T-cell': '0.1', 'Memory CD8 T-cell': '0.2', 'Naive CD8 T-cell': '0.3', 'Memory B-cell': '0.0', 'Naive B-cell': '0.1', 'Plasmacytoid DC': '46.6', 'Myeloid DC': '8.5', 'NK-cell': '0.1', 'Total PBMC': '0.7', 'Vd2 gdTCR': '0.0', 'Memory CD4 T-cell Th1\\/Th17': '0.1', 'Memory CD4 T-cell Th17': '0.2', 'Memory CD4 T-cell Th2': '2.9', 'Non-Vd2 gdTCR': '0.1', 'Memory CD4 T-cell Th1': '0.3', 'Memory CD4 T-cell TFH': '0.5', 'Terminal effector memory CD4 T-cell': '0.0', 'Central memory CD8 T-cell': '4.8', 'Effector memory CD8 T-cell': '0.0', 'Terminal effector memory CD8 T-cell': '0.6', 'Non-switched memory B-cell': '0.0', 'Plasmablast': '3.3', 'Switched memory B-cell': '0.0', 'Exhausted memory B-cell': '0.7', 'Progenitor cell': '2.3', 'Memory T-reg': '1.3', 'Naive CD4 T-cell activated': '0.3', 'Naive CD8 T-cell activated': '0.6', 'Naive T-reg': '0.1'} | 1O6S, 2O72, 2OMT, 2OMU, 2OMV, 2OMX, 2OMY, 2OMZ, 3FF7, 3FF8, 3L6X, 3L6Y, 4ZT1, 4ZTE, 6CXY, 6OLE, 6OLF, 6OLG, 6VEL, 7STZ, 8H62 | {'Adipose Tissue': 1.2125261088039867, 'Adrenal Gland': 0.1914223992248062, 'Bladder': 39.2033519047619, 'Blood': 1.340954264800861, 'Blood Vessel': 0.3121561692883895, 'Brain': 0.8550442199091597, 'Breast': 38.54918344226579, 'Cervix Uteri': 23.539115789473684, 'Colon': 43.41292142490372, 'Esophagus': 53.97513367404844, 'Fallopian Tube': 14.900277777777776, 'Heart': 0.119140469221835, 'Kidney': 25.040449438202245, 'Liver': 26.60802654867257, 'Lung': 35.447986366782004, 'Muscle': 0.1378936151930261, 'Nerve': 17.518468982229404, 'Ovary': 3.6515122222222223, 'Pancreas': 56.89676829268293, 'Pituitary': 24.68741660777385, 'Prostate': 61.279967346938776, 'Salivary Gland': 92.01685185185184, 'Skin': 79.77571720232172, 'Small Intestine': 71.7519320855615, 'Spleen': 10.061029045643156, 'Stomach': 58.07813805013927, 'Testis': 0.8144204986149585, 'Thyroid': 135.176797856049, 'Uterus': 1.442593943661972, 'Vagina': 86.52345512820513} | CUEDC2 | MELERIVSAALLAFVQTHLPEADLSGLDEVIFSYVLGVLEDLGPSGPSEENFDMEAFTEMMEAYVPGFAHIPRGTIGDMMQKLSGQLSDARNKENLQPQSSGVQGQVPISPEPLQRPEMLKEETRSSAAAAADTQDEATGAEEELLPGVDVLLEVFPTCSVEQAQWVLAKARGDLEEAVQMLVEGKEEGPAAWEGPNQDLPRRLRGPQKDELKSFILQKYMMVDSAEDQKIHRPMAPKEAPKKLIRYIDNQVVSTKGERFKDVRNPEAEEMKATYINLKPARKYRFH | Homo sapiens | Cytoplasm, Nucleus | Low tissue specificity | {'Ciliated cells': '35.9', 'Basal respiratory cells': '69.2', 'Club cells': '41.5', 'Ionocytes': '43.1', 'Mucus glandular cells': '40.5', 'Serous glandular cells': '31.0', 'Gastric mucus-secreting cells': '29.5', 'Proximal enterocytes': '31.1', 'Paneth cells': '39.2', 'Distal enterocytes': '20.4', 'Intestinal goblet cells': '29.0', 'Exocrine glandular cells': '-0.712', 'Basal prostatic cells': '38.7', 'Prostatic glandular cells': '45.1', 'Breast glandular cells': '0.338', 'Breast myoepithelial cells': '0.230', 'Glandular and luminal cells': '29.6', 'Secretory cells': '68.3', 'Basal keratinocytes': '37.4', 'Suprabasal keratinocytes': '30.9', 'Basal squamous epithelial cells': '42.3', 'Squamous epithelial cells': '39.9', 'Alveolar cells type 1': '-0.148', 'Alveolar cells type 2': '-0.145', 'Salivary duct cells': '38.4', 'Ductal cells': '0.576', 'Hepatocytes': '0.508', 'Cholangiocytes': '32.4', 'Proximal tubular cells': '0.222', 'Distal tubular cells': '52.2', 'Collecting duct cells': '38.9', 'Mesothelial cells': '0.472', 'Sertoli cells': '0.066', 'Granulosa cells': '72.3', 'Enteroendocrine cells': '55.7', 'Pancreatic endocrine cells': '61.1', 'Leydig cells': '0.008', 'Excitatory neurons': '11.8', 'Inhibitory neurons': '15.4', 'Cone photoreceptor cells': '62.9', 'Rod photoreceptor cells': '32.6', 'Bipolar cells': '53.1', 'Horizontal cells': '49.7', 'Astrocytes': '10.2', 'Oligodendrocyte precursor cells': '12.7', 'Oligodendrocytes': '21.8', 'Microglial cells': '3.6', 'Muller glia cells': '85.1', 'Schwann cells': '0.088', 'Spermatogonia': '0.062', 'Spermatocytes': '0.027', 'Early spermatids': '0.117', 'Late spermatids': '-0.031', 'Oocytes': '33.1', 'Cytotrophoblasts': '68.3', 'Syncytiotrophoblasts': '39.1', 'Extravillous trophoblasts': '32.4', 'Endothelial cells': '45.2', 'Lymphatic endothelial cells': '65.0', 'Cardiomyocytes': '0.761', 'Skeletal myocytes': '0.174', 'Smooth muscle cells': '61.9', 'Adipocytes': '54.5', 'Melanocytes': '0.117', 'Fibroblasts': '56.8', 'Peritubular cells': '-0.008', 'Endometrial stromal cells': '53.2', 'Ovarian stromal cells': '87.9', 'Undifferentiated cells': '53.2', 'T-cells': '34.0', 'B-cells': '30.9', 'Plasma cells': '47.0', 'Nk-cells': '32.6', 'Granulocytes': '38.4', 'Monocytes': '29.3', 'Macrophages': '42.3', 'Hofbauer cells': '81.9', 'Kupffer cells': '40.7', 'Dendritic cells': '41.4', 'Langerhans cells': '0.149', 'Erythroid cells': '-0.011', 'Adipocytes (Subcutaneous)': '-0.069', 'Adipocytes (Visceral)': '-0.132', 'Breast glandular cells (progenitors)': '0.230', 'Adipocytes (Breast)': '-0.167', 'Colon enterocytes': '-0.333', 'Colon enteroendocrine cells': '0.193', 'Enteric glia cells': '0.315', 'Mitotic cells (Colon)': '-0.252', 'Mitotic cells (Heart)': '0.431', 'Podocytes': '-0.059', 'Ascending Loop of Henle cells': '0.485', 'Intercalated cells': '0.044', 'Cholangiocyte': '0.386', 'NK-cells (Liver)': '-0.303', 'Respiratory ciliated cells': '-0.025', 'Mitotic cells (Lung)': '0.205', 'NK-cells (Lung)': '-0.130', 'B-cells (Lung)': '-0.154', 'Alpha cells': '0.425', 'Beta cells': '0.248', 'Prostate glandular cells': '0.012', 'Prostate basal glandular cells': '0.049', 'Urothelial cells': '-0.058', 'Keratinocyte (other)': '-0.158', 'Keratinocyte (granular)': '-0.181', 'Hair cortex cells': '0.192', 'Inner root sheath cells': '0.130', 'Outer root sheath cells': '0.258', 'Sebaceous gland cells': '0.060', 'Eccrine sweat gland cells': '0.182', 'Adipocytes (Skin)': '0.220', 'Mitotic cells (Skin)': '0.100', 'Parietal cells': '-0.715', 'Chief cells': '-0.532', 'Gastric mucous cells': '-0.488', 'Gastric enteroendocrine cells': '-0.456', 'Mitotic cells (Stomach)': '-0.023', 'Parafollicular cells': '0.115', 'Thyroid glandular cells': '0.480', 'Mitotic cells (Thyroid)': '-0.012', 'Adrenal cortex cells': '0.426', 'Adrenal medulla cells': '0.042', 'Mitotic cells (Adrenal gland)': '0.406', 'Minor salivary glandular cells': '0.534', 'Minor salivary gland ductal cells': '0.074', 'Minor salivary gland basal cells': '0.019', 'Mitotic cells (Minor salivary gland)': '0.225', 'Adipocytes (Minor salivary gland)': '0.165', 'Somatotropes': '-0.146', 'Lactotropes': '-0.084', 'Gonadotropes': '0.004', 'Corticotropes': '-0.161', 'Thyrotropes': '0.142', 'Undifferentiated cells (Pituitary gland)': '0.469', 'Mitotic cells (Spleen)': '-0.384', 'Platelets': '-0.150', 'Erythrocytes': '-0.046', 'Hematopoietic stem cells': '-0.158', 'B-cells (Spleen)': '0.175', 'NK-cells (Spleen)': '0.150', 'Amygdala excitatory': '14.2', 'Cerebellar inhibitory': '31.1', 'Cge interneuron': '27.2', 'Deep-layer corticothalamic and 6b': '17.2', 'Deep-layer intratelencephalic': '18.0', 'Deep-layer near-projecting': '20.4', 'Eccentric medium spiny neuron': '15.6', 'Hippocampal ca1-3': '18.0', 'Hippocampal ca4': '23.0', 'Hippocampal dentate gyrus': '20.8', 'Lamp5-lhx6 and chandelier': '27.5', 'Lower rhombic lip': '30.2', 'Mammillary body': '18.4', 'Medium spiny neuron': '14.0', 'Mge interneuron': '22.4', 'Midbrain-derived inhibitory': '25.5', 'Miscellaneous': '20.1', 'Splatter': '21.6', 'Thalamic excitatory': '22.0', 'Upper rhombic lip': '31.3', 'Upper-layer intratelencephalic': '16.6', 'Astrocyte': '19.7', 'Bergmann glia': '29.8', 'Central nervous system macrophage': '15.3', 'Choroid plexus epithelial cell': '17.5', 'Committed oligodendrocyte precursor': '45.1', 'Ependymal cell': '22.4', 'Oligodendrocyte': '37.0', 'Oligodendrocyte precursor cell': '30.9', 'Endothelial cell': '21.4', 'Pericyte': '35.2', 'Vascular associated smooth muscle cell': '23.9', 'Fibroblast': '17.8', 'Leukocyte': '13.8', 'Basophil': '44.9', 'Eosinophil': '84.6', 'Neutrophil': '39.3', 'Classical monocyte': '70.0', 'Non-classical monocyte': '41.1', 'Intermediate monocyte': '70.6', 'T-reg': '53.0', 'GdT-cell': '69.3', 'MAIT T-cell': '57.1', 'Memory CD4 T-cell': '67.1', 'Naive CD4 T-cell': '47.4', 'Memory CD8 T-cell': '72.4', 'Naive CD8 T-cell': '66.4', 'Memory B-cell': '80.9', 'Naive B-cell': '37.9', 'Plasmacytoid DC': '83.0', 'Myeloid DC': '93.7', 'NK-cell': '66.2', 'Total PBMC': '86.0', 'Vd2 gdTCR': '65.5', 'Memory CD4 T-cell Th1\\/Th17': '54.0', 'Memory CD4 T-cell Th17': '64.9', 'Memory CD4 T-cell Th2': '63.2', 'Non-Vd2 gdTCR': '57.4', 'Memory CD4 T-cell Th1': '68.6', 'Memory CD4 T-cell TFH': '78.9', 'Terminal effector memory CD4 T-cell': '42.5', 'Central memory CD8 T-cell': '50.8', 'Effector memory CD8 T-cell': '49.0', 'Terminal effector memory CD8 T-cell': '58.4', 'Non-switched memory B-cell': '67.5', 'Plasmablast': '66.3', 'Switched memory B-cell': '54.6', 'Exhausted memory B-cell': '49.5', 'Progenitor cell': '69.2', 'Memory T-reg': '84.7', 'Naive CD4 T-cell activated': '22.9', 'Naive CD8 T-cell activated': '39.4', 'Naive T-reg': '52.0'} | null | {'Adipose Tissue': 70.20386212624584, 'Adrenal Gland': 83.49833333333333, 'Bladder': 83.17380952380952, 'Blood': 47.83628417653391, 'Blood Vessel': 86.22140823970038, 'Brain': 74.94496971990915, 'Breast': 71.57019607843138, 'Cervix Uteri': 99.97947368421052, 'Colon': 81.23830551989731, 'Esophagus': 73.35456747404845, 'Fallopian Tube': 100.01222222222222, 'Heart': 55.277292682926834, 'Kidney': 55.67651685393258, 'Liver': 29.18770353982301, 'Lung': 72.19313148788927, 'Muscle': 69.41124533001246, 'Nerve': 192.85720516962843, 'Ovary': 106.9572222222222, 'Pancreas': 25.875807926829268, 'Pituitary': 81.85802120141342, 'Prostate': 86.8814693877551, 'Salivary Gland': 52.31728395061728, 'Skin': 73.06685461580985, 'Small Intestine': 55.73283422459893, 'Spleen': 72.95228215767635, 'Stomach': 59.63924791086352, 'Testis': 80.23013850415514, 'Thyroid': 87.14828483920368, 'Uterus': 108.33161971830988, 'Vagina': 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1.0, 1.0, 1.0, 1.0, 1.0, 0.99, 0.89, 0.96, 0.86, 0.94, 0.91, 0.89, 0.9, 0.95, 0.76, 0.9, 0.73, 0.88, 0.37, 0.55, 0.86, 0.13, 0.0, 0.55, 0.42, 0.0, 0.28, 0.82, 0.64, 0.25, 0.77, 0.62, 0.08, 0.25, 0.41, 0.68, 0.18, 0.0, 0.31, 0.31, 0.07, 0.05, 0.63, 0.38, 0.14, 0.9, 0.59, 0.47, 0.34, 0.79, 0.59, 0.0, 0.32, 0.49, 0.24, 0.26, 0.65, 0.44, 0.55, 0.64, 0.75, 0.72, 0.35, 0.46, 0.75, 0.87, 0.32, 0.69, 0.6, 0.96, 0.8, 0.62, 0.84, 0.86, 0.9, 0.75, 0.9, 0.84, 0.88, 0.76, 0.34, 0.66, 0.87, 0.87, 0.59, 0.4, 0.74, 0.52, 0.47, 0.49, 0.51, 0.84, 0.75, 0.76, 0.58, 0.93, 0.62, 0.58, 0.63, 0.56, 0.5, 0.81, 0.78, 0.63, 0.77, 0.8, 0.87, 0.72, 0.84, 0.86, 0.91, 0.83, 0.77, 0.76, 0.88, 0.69, 0.9, 0.37, 0.54, 0.52, 0.64, 0.52, 0.91, 0.86, 0.69, 0.53, 0.21, 0.05, 0.54, 0.79, 0.34, 0.55, 0.89, 0.79, 0.49, 0.77, 0.52, 0.72, 0.63, 0.59, 0.68, 0.43, 0.49, 0.66, 0.65, 0.76, 0.79, 0.69, 0.72, 0.76, 0.72, 0.83, 0.93, 0.89, 0.83, 0.91, 0.91, 0.84, 0.95, 0.89, 0.98] | null | Component of an E-cadherin/ catenin adhesion complex composed of at least E-cadherin/CDH1, beta-catenin/CTNNB1 or gamma-catenin/JUP, and potentially alpha-catenin/CTNNA1. Forms a ternary complex composed of ADAM10, CADH1 and EPHA4, | null | null | KLRG1, SPEF1, DLGAP5, AJAP1, RAPGEF2, RAB8B, PIP5K1C, PKP2, TRPV4, CTNNB1, CAV1, DDR1, TBC1D2, CTNNA1, JUP, CTNND1, PSEN1, LIMA1, CDH1, JUP, ADAM10, CADH1 , EPHA4, | null | null | null | null | Homodimer | null | 79.91949 | 0.474025 | 72.817491 | 0.590627 | 2,439 |
P12830 | Q9NQW6 | null | degron_data | CDH1 | MGPWSRSLSALLLLLQVSSWLCQEPEPCHPGFDAESYTFTVPRRHLERGRVLGRVNFEDCTGRQRTAYFSLDTRFKVGTDGVITVKRPLRFHNPQIHFLVYAWDSTYRKFSTKVTLNTVGHHHRPPPHQASVSGIQAELLTFPNSSPGLRRQKRDWVIPPISCPENEKGPFPKNLVQIKSNKDKEGKVFYSITGQGADTPPVGVFIIERETGWLKVTEPLDRERIATYTLFSHAVSSNGNAVEDPMEILITVTDQNDNKPEFTQEVFKGSVMEGALPGTSVMEVTATDADDDVNTYNAAIAYTILSQDPELPDKNMFTINRNTGVISVVTTGLDRESFPTYTLVVQAADLQGEGLSTTATAVITVTDTNDNPPIFNPTTYKGQVPENEANVVITTLKVTDADAPNTPAWEAVYTILNDDGGQFVVTTNPVNNDGILKTAKGLDFEAKQQYILHVAVTNVVPFEVSLTTSTATVTVDVLDVNEAPIFVPPEKRVEVSEDFGVGQEITSYTAQEPDTFMEQKITYRIWRDTANWLEINPDTGAISTRAELDREDFEHVKNSTYTALIIATDNGSPVATGTGTLLLILSDVNDNAPIPEPRTIFFCERNPKPQVINIIDADLPPNTSPFTAELTHGASANWTIQYNDPTQESIILKPKMALEVGDYKINLKLMDNQNKDQVTTLEVSVCDCEGAAGVCRKAQPVEAGLQIPAILGILGGILALLILILLLLLFLRRRAVVKEPLLPPEDDTRDNVYYYDEEGGGEEDQDFDLSQLHRGLDARPEVTRNDVAPTLMSVPRYLPRPANPDEIGNFIDENLKAADTDPTAPPYDSLLVFDYEGSGSEAASLSSLNSSESDKDQDYDYLNEWGNRFKKLADMYGGGEDD | Homo sapiens | Cell junction, adherens junction, Cell membrane, Endosome, Golgi apparatus, trans-Golgi network, Cytoplasm, Cell junction, desmosome | Tissue enhanced (parathyroid) | {'Ciliated cells': '119.1', 'Basal respiratory cells': '71.1', 'Club cells': '97.3', 'Ionocytes': '81.0', 'Mucus glandular cells': '155.0', 'Serous glandular cells': '67.8', 'Gastric mucus-secreting cells': '133.2', 'Proximal enterocytes': '140.9', 'Paneth cells': '125.1', 'Distal enterocytes': '307.5', 'Intestinal goblet cells': '173.5', 'Exocrine glandular cells': '-0.605', 'Basal prostatic cells': '68.3', 'Prostatic glandular cells': '186.7', 'Breast glandular cells': '0.773', 'Breast myoepithelial cells': '0.700', 'Glandular and luminal cells': '313.0', 'Secretory cells': '82.3', 'Basal keratinocytes': '102.5', 'Suprabasal keratinocytes': '162.6', 'Basal squamous epithelial cells': '51.0', 'Squamous epithelial cells': '106.9', 'Alveolar cells type 1': '0.437', 'Alveolar cells type 2': '0.706', 'Salivary duct cells': '95.9', 'Ductal cells': '0.541', 'Hepatocytes': '0.600', 'Cholangiocytes': '129.7', 'Proximal tubular cells': '0.042', 'Distal tubular cells': '0.0', 'Collecting duct cells': '143.9', 'Mesothelial cells': '0.799', 'Sertoli cells': '0.252', 'Granulosa cells': '12.9', 'Enteroendocrine cells': '92.4', 'Pancreatic endocrine cells': '78.1', 'Leydig cells': '0.264', 'Excitatory neurons': '0.7', 'Inhibitory neurons': '1.3', 'Cone photoreceptor cells': '0.0', 'Rod photoreceptor cells': '0.0', 'Bipolar cells': '0.2', 'Horizontal cells': '0.6', 'Astrocytes': '0.6', 'Oligodendrocyte precursor cells': '0.5', 'Oligodendrocytes': '29.9', 'Microglial cells': '0.9', 'Muller glia cells': '0.1', 'Schwann cells': '0.131', 'Spermatogonia': '0.392', 'Spermatocytes': '0.193', 'Early spermatids': '-0.217', 'Late spermatids': '-0.290', 'Oocytes': '16.9', 'Cytotrophoblasts': '119.2', 'Syncytiotrophoblasts': '45.0', 'Extravillous trophoblasts': '24.9', 'Endothelial cells': '6.1', 'Lymphatic endothelial cells': '0.4', 'Cardiomyocytes': '0.135', 'Skeletal myocytes': '0.107', 'Smooth muscle cells': '5.8', 'Adipocytes': '2.1', 'Melanocytes': '0.335', 'Fibroblasts': '6.5', 'Peritubular cells': '0.210', 'Endometrial stromal cells': '27.7', 'Ovarian stromal cells': '0.7', 'Undifferentiated cells': '101.6', 'T-cells': '2.9', 'B-cells': '4.4', 'Plasma cells': '6.1', 'Nk-cells': '0.0', 'Granulocytes': '8.4', 'Monocytes': '0.0', 'Macrophages': '6.0', 'Hofbauer cells': '4.3', 'Kupffer cells': '1.0', 'Dendritic cells': '5.9', 'Langerhans cells': '0.304', 'Erythroid cells': '0.036', 'Adipocytes (Subcutaneous)': '-0.081', 'Adipocytes (Visceral)': '-0.209', 'Breast glandular cells (progenitors)': '0.538', 'Adipocytes (Breast)': '-0.689', 'Colon enterocytes': '0.790', 'Colon enteroendocrine cells': '0.112', 'Enteric glia cells': '-0.048', 'Mitotic cells (Colon)': '0.299', 'Mitotic cells (Heart)': '0.120', 'Podocytes': '-0.118', 'Ascending Loop of Henle cells': '0.475', 'Intercalated cells': '0.212', 'Cholangiocyte': '0.090', 'NK-cells (Liver)': '-0.005', 'Respiratory ciliated cells': '-0.012', 'Mitotic cells (Lung)': '0.071', 'NK-cells (Lung)': '-0.266', 'B-cells (Lung)': '-0.296', 'Alpha cells': '0.270', 'Beta cells': '0.152', 'Prostate glandular cells': '0.764', 'Prostate basal glandular cells': '0.540', 'Urothelial cells': '0.205', 'Keratinocyte (other)': '0.510', 'Keratinocyte (granular)': '0.055', 'Hair cortex cells': '0.080', 'Inner root sheath cells': '0.131', 'Outer root sheath cells': '0.175', 'Sebaceous gland cells': '0.156', 'Eccrine sweat gland cells': '-0.207', 'Adipocytes (Skin)': '-0.244', 'Mitotic cells (Skin)': '0.442', 'Parietal cells': '0.654', 'Chief cells': '0.649', 'Gastric mucous cells': '0.781', 'Gastric enteroendocrine cells': '0.590', 'Mitotic cells (Stomach)': '0.445', 'Parafollicular cells': '0.173', 'Thyroid glandular cells': '0.865', 'Mitotic cells (Thyroid)': '-0.081', 'Adrenal cortex cells': '0.051', 'Adrenal medulla cells': '0.087', 'Mitotic cells (Adrenal gland)': '0.072', 'Minor salivary glandular cells': '0.371', 'Minor salivary gland ductal cells': '-0.142', 'Minor salivary gland basal cells': '0.582', 'Mitotic cells (Minor salivary gland)': '0.567', 'Adipocytes (Minor salivary gland)': '0.050', 'Somatotropes': '0.121', 'Lactotropes': '0.322', 'Gonadotropes': '0.330', 'Corticotropes': '0.180', 'Thyrotropes': '0.496', 'Undifferentiated cells (Pituitary gland)': '-0.108', 'Mitotic cells (Spleen)': '-0.228', 'Platelets': '-0.050', 'Erythrocytes': '-0.158', 'Hematopoietic stem cells': '-0.211', 'B-cells (Spleen)': '0.266', 'NK-cells (Spleen)': '0.309', 'Amygdala excitatory': '1.0', 'Cerebellar inhibitory': '0.9', 'Cge interneuron': '0.7', 'Deep-layer corticothalamic and 6b': '1.5', 'Deep-layer intratelencephalic': '0.7', 'Deep-layer near-projecting': '0.7', 'Eccentric medium spiny neuron': '0.6', 'Hippocampal ca1-3': '1.9', 'Hippocampal ca4': '1.2', 'Hippocampal dentate gyrus': '1.1', 'Lamp5-lhx6 and chandelier': '0.5', 'Lower rhombic lip': '0.8', 'Mammillary body': '0.6', 'Medium spiny neuron': '0.7', 'Mge interneuron': '1.7', 'Midbrain-derived inhibitory': '0.7', 'Miscellaneous': '0.9', 'Splatter': '3.8', 'Thalamic excitatory': '0.5', 'Upper rhombic lip': '0.8', 'Upper-layer intratelencephalic': '0.6', 'Astrocyte': '4.4', 'Bergmann glia': '0.2', 'Central nervous system macrophage': '0.6', 'Choroid plexus epithelial cell': '52.1', 'Committed oligodendrocyte precursor': '41.5', 'Ependymal cell': '4.8', 'Oligodendrocyte': '53.1', 'Oligodendrocyte precursor cell': '2.4', 'Endothelial cell': '0.7', 'Pericyte': '0.3', 'Vascular associated smooth muscle cell': '0.0', 'Fibroblast': '17.4', 'Leukocyte': '1.1', 'Basophil': '0.0', 'Eosinophil': '0.0', 'Neutrophil': '0.0', 'Classical monocyte': '0.0', 'Non-classical monocyte': '0.0', 'Intermediate monocyte': '0.0', 'T-reg': '2.3', 'GdT-cell': '0.0', 'MAIT T-cell': '0.0', 'Memory CD4 T-cell': '0.0', 'Naive CD4 T-cell': '0.1', 'Memory CD8 T-cell': '0.2', 'Naive CD8 T-cell': '0.3', 'Memory B-cell': '0.0', 'Naive B-cell': '0.1', 'Plasmacytoid DC': '46.6', 'Myeloid DC': '8.5', 'NK-cell': '0.1', 'Total PBMC': '0.7', 'Vd2 gdTCR': '0.0', 'Memory CD4 T-cell Th1\\/Th17': '0.1', 'Memory CD4 T-cell Th17': '0.2', 'Memory CD4 T-cell Th2': '2.9', 'Non-Vd2 gdTCR': '0.1', 'Memory CD4 T-cell Th1': '0.3', 'Memory CD4 T-cell TFH': '0.5', 'Terminal effector memory CD4 T-cell': '0.0', 'Central memory CD8 T-cell': '4.8', 'Effector memory CD8 T-cell': '0.0', 'Terminal effector memory CD8 T-cell': '0.6', 'Non-switched memory B-cell': '0.0', 'Plasmablast': '3.3', 'Switched memory B-cell': '0.0', 'Exhausted memory B-cell': '0.7', 'Progenitor cell': '2.3', 'Memory T-reg': '1.3', 'Naive CD4 T-cell activated': '0.3', 'Naive CD8 T-cell activated': '0.6', 'Naive T-reg': '0.1'} | 1O6S, 2O72, 2OMT, 2OMU, 2OMV, 2OMX, 2OMY, 2OMZ, 3FF7, 3FF8, 3L6X, 3L6Y, 4ZT1, 4ZTE, 6CXY, 6OLE, 6OLF, 6OLG, 6VEL, 7STZ, 8H62 | {'Adipose Tissue': 1.2125261088039867, 'Adrenal Gland': 0.1914223992248062, 'Bladder': 39.2033519047619, 'Blood': 1.340954264800861, 'Blood Vessel': 0.3121561692883895, 'Brain': 0.8550442199091597, 'Breast': 38.54918344226579, 'Cervix Uteri': 23.539115789473684, 'Colon': 43.41292142490372, 'Esophagus': 53.97513367404844, 'Fallopian Tube': 14.900277777777776, 'Heart': 0.119140469221835, 'Kidney': 25.040449438202245, 'Liver': 26.60802654867257, 'Lung': 35.447986366782004, 'Muscle': 0.1378936151930261, 'Nerve': 17.518468982229404, 'Ovary': 3.6515122222222223, 'Pancreas': 56.89676829268293, 'Pituitary': 24.68741660777385, 'Prostate': 61.279967346938776, 'Salivary Gland': 92.01685185185184, 'Skin': 79.77571720232172, 'Small Intestine': 71.7519320855615, 'Spleen': 10.061029045643156, 'Stomach': 58.07813805013927, 'Testis': 0.8144204986149585, 'Thyroid': 135.176797856049, 'Uterus': 1.442593943661972, 'Vagina': 86.52345512820513} | ANLN | MDPFTEKLLERTRARRENLQRKMAERPTAAPRSMTHAKRARQPLSEASNQQPLSGGEEKSCTKPSPSKKRCSDNTEVEVSNLENKQPVESTSAKSCSPSPVSPQVQPQAADTISDSVAVPASLLGMRRGLNSRLEATAASSVKTRMQKLAEQRRRWDNDDMTDDIPESSLFSPMPSEEKAASPPRPLLSNASATPVGRRGRLANLAATICSWEDDVNHSFAKQNSVQEQPGTACLSKFSSASGASARINSSSVKQEATFCSQRDGDASLNKALSSSADDASLVNASISSSVKATSPVKSTTSITDAKSCEGQNPELLPKTPISPLKTGVSKPIVKSTLSQTVPSKGELSREICLQSQSKDKSTTPGGTGIKPFLERFGERCQEHSKESPARSTPHRTPIITPNTKAIQERLFKQDTSSSTTHLAQQLKQERQKELACLRGRFDKGNIWSAEKGGNSKSKQLETKQETHCQSTPLKKHQGVSKTQSLPVTEKVTENQIPAKNSSTEPKGFTECEMTKSSPLKITLFLEEDKSLKVTSDPKVEQKIEVIREIEMSVDDDDINSSKVINDLFSDVLEEGELDMEKSQEEMDQALAESSEEQEDALNISSMSLLAPLAQTVGVVSPESLVSTPRLELKDTSRSDESPKPGKFQRTRVPRAESGDSLGSEDRDLLYSIDAYRSQRFKETERPSIKQVIVRKEDVTSKLDEKNNAFPCQVNIKQKMQELNNEINMQQTVIYQASQALNCCVDEEHGKGSLEEAEAERLLLIATGKRTLLIDELNKLKNEGPQRKNKASPQSEFMPSKGSVTLSEIRLPLKADFVCSTVQKPDAANYYYLIILKAGAENMVATPLASTSNSLNGDALTFTTTFTLQDVSNDFEINIEVYSLVQKKDPSGLDKKKKTSKSKAITPKRLLTSITTKSNIHSSVMASPGGLSAVRTSNFALVGSYTLSLSSVGNTKFVLDKVPFLSSLEGHIYLKIKCQVNSSVEERGFLTIFEDVSGFGAWHRRWCVLSGNCISYWTYPDDEKRKNPIGRINLANCTSRQIEPANREFCARRNTFELITVRPQREDDRETLVSQCRDTLCVTKNWLSADTKEERDLWMQKLNQVLVDIRLWQPDACYKPIGKP | Homo sapiens | Nucleus, Cytoplasm, cytoskeleton, Cytoplasm, cell cortex, Cell projection, bleb | Tissue enriched (brain) | {'Ciliated cells': '11.2', 'Basal respiratory cells': '7.8', 'Club cells': '3.6', 'Ionocytes': '7.4', 'Mucus glandular cells': '3.2', 'Serous glandular cells': '0.2', 'Gastric mucus-secreting cells': '11.8', 'Proximal enterocytes': '0.1', 'Paneth cells': '1.4', 'Distal enterocytes': '0.6', 'Intestinal goblet cells': '3.0', 'Exocrine glandular cells': '-0.326', 'Basal prostatic cells': '0.2', 'Prostatic glandular cells': '0.0', 'Breast glandular cells': '0.155', 'Breast myoepithelial cells': '0.317', 'Glandular and luminal cells': '9.7', 'Secretory cells': '0.6', 'Basal keratinocytes': '15.9', 'Suprabasal keratinocytes': '9.3', 'Basal squamous epithelial cells': '12.4', 'Squamous epithelial cells': '24.5', 'Alveolar cells type 1': '-0.251', 'Alveolar cells type 2': '0.121', 'Salivary duct cells': '4.5', 'Ductal cells': '0.529', 'Hepatocytes': '0.257', 'Cholangiocytes': '0.0', 'Proximal tubular cells': '0.176', 'Distal tubular cells': '0.0', 'Collecting duct cells': '0.0', 'Mesothelial cells': '0.361', 'Sertoli cells': '-0.143', 'Granulosa cells': '5.2', 'Enteroendocrine cells': '0.3', 'Pancreatic endocrine cells': '6.8', 'Leydig cells': '-0.131', 'Excitatory neurons': '3.3', 'Inhibitory neurons': '5.4', 'Cone photoreceptor cells': '0.0', 'Rod photoreceptor cells': '0.0', 'Bipolar cells': '0.2', 'Horizontal cells': '0.0', 'Astrocytes': '2.2', 'Oligodendrocyte precursor cells': '1.4', 'Oligodendrocytes': '410.7', 'Microglial cells': '0.0', 'Muller glia cells': '0.0', 'Schwann cells': '0.126', 'Spermatogonia': '0.408', 'Spermatocytes': '0.800', 'Early spermatids': '0.518', 'Late spermatids': '0.182', 'Oocytes': '20.6', 'Cytotrophoblasts': '13.9', 'Syncytiotrophoblasts': '3.3', 'Extravillous trophoblasts': '23.4', 'Endothelial cells': '1.2', 'Lymphatic endothelial cells': '0.1', 'Cardiomyocytes': '0.422', 'Skeletal myocytes': '0.113', 'Smooth muscle cells': '2.6', 'Adipocytes': '0.3', 'Melanocytes': '0.473', 'Fibroblasts': '3.5', 'Peritubular cells': '-0.164', 'Endometrial stromal cells': '2.3', 'Ovarian stromal cells': '1.4', 'Undifferentiated cells': '13.6', 'T-cells': '1.3', 'B-cells': '0.7', 'Plasma cells': '9.2', 'Nk-cells': '1.2', 'Granulocytes': '0.0', 'Monocytes': '0.2', 'Macrophages': '3.8', 'Hofbauer cells': '7.6', 'Kupffer cells': '2.5', 'Dendritic cells': '0.8', 'Langerhans cells': '0.269', 'Erythroid cells': '0.139', 'Adipocytes (Subcutaneous)': '-0.188', 'Adipocytes (Visceral)': '-0.214', 'Breast glandular cells (progenitors)': '0.239', 'Adipocytes (Breast)': '-0.125', 'Colon enterocytes': '0.130', 'Colon enteroendocrine cells': '-0.010', 'Enteric glia cells': '-0.233', 'Mitotic cells (Colon)': '0.405', 'Mitotic cells (Heart)': '0.756', 'Podocytes': '-0.244', 'Ascending Loop of Henle cells': '0.393', 'Intercalated cells': '-0.232', 'Cholangiocyte': '0.295', 'NK-cells (Liver)': '-0.113', 'Respiratory ciliated cells': '0.021', 'Mitotic cells (Lung)': '0.938', 'NK-cells (Lung)': '-0.132', 'B-cells (Lung)': '-0.010', 'Alpha cells': '0.222', 'Beta cells': '0.058', 'Prostate glandular cells': '-0.209', 'Prostate basal glandular cells': '0.090', 'Urothelial cells': '0.113', 'Keratinocyte (other)': '0.528', 'Keratinocyte (granular)': '0.032', 'Hair cortex cells': '-0.104', 'Inner root sheath cells': '0.000', 'Outer root sheath cells': '0.017', 'Sebaceous gland cells': '-0.060', 'Eccrine sweat gland cells': '-0.113', 'Adipocytes (Skin)': '-0.278', 'Mitotic cells (Skin)': '0.821', 'Parietal cells': '-0.274', 'Chief cells': '-0.278', 'Gastric mucous cells': '0.198', 'Gastric enteroendocrine cells': '-0.145', 'Mitotic cells (Stomach)': '0.787', 'Parafollicular cells': '0.014', 'Thyroid glandular cells': '-0.067', 'Mitotic cells (Thyroid)': '0.731', 'Adrenal cortex cells': '0.476', 'Adrenal medulla cells': '0.115', 'Mitotic cells (Adrenal gland)': '0.930', 'Minor salivary glandular cells': 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0.28, 0.0, 0.09, 0.17, 0.05, 0.02, 0.23, 0.02, 0.1, 0.31, 0.32, 0.0, 0.4, 0.35, 0.71, 0.41, 0.22, 0.29, 0.64, 0.75, 0.85, 0.84, 0.97, 0.97] | null | Component of an E-cadherin/ catenin adhesion complex composed of at least E-cadherin/CDH1, beta-catenin/CTNNB1 or gamma-catenin/JUP, and potentially alpha-catenin/CTNNA1. Forms a ternary complex composed of ADAM10, CADH1 and EPHA4, | null | null | KLRG1, SPEF1, DLGAP5, AJAP1, RAPGEF2, RAB8B, PIP5K1C, PKP2, TRPV4, CTNNB1, CAV1, DDR1, TBC1D2, CTNNA1, JUP, CTNND1, PSEN1, LIMA1, CDH1, JUP, ADAM10, CADH1 , EPHA4, | null | null | null | null | Homodimer | null | 79.91949 | 0.474025 | 58.972367 | 0.710418 | 393 |
P12830 | Q9NYD6 | null | degron_data | CDH1 | MGPWSRSLSALLLLLQVSSWLCQEPEPCHPGFDAESYTFTVPRRHLERGRVLGRVNFEDCTGRQRTAYFSLDTRFKVGTDGVITVKRPLRFHNPQIHFLVYAWDSTYRKFSTKVTLNTVGHHHRPPPHQASVSGIQAELLTFPNSSPGLRRQKRDWVIPPISCPENEKGPFPKNLVQIKSNKDKEGKVFYSITGQGADTPPVGVFIIERETGWLKVTEPLDRERIATYTLFSHAVSSNGNAVEDPMEILITVTDQNDNKPEFTQEVFKGSVMEGALPGTSVMEVTATDADDDVNTYNAAIAYTILSQDPELPDKNMFTINRNTGVISVVTTGLDRESFPTYTLVVQAADLQGEGLSTTATAVITVTDTNDNPPIFNPTTYKGQVPENEANVVITTLKVTDADAPNTPAWEAVYTILNDDGGQFVVTTNPVNNDGILKTAKGLDFEAKQQYILHVAVTNVVPFEVSLTTSTATVTVDVLDVNEAPIFVPPEKRVEVSEDFGVGQEITSYTAQEPDTFMEQKITYRIWRDTANWLEINPDTGAISTRAELDREDFEHVKNSTYTALIIATDNGSPVATGTGTLLLILSDVNDNAPIPEPRTIFFCERNPKPQVINIIDADLPPNTSPFTAELTHGASANWTIQYNDPTQESIILKPKMALEVGDYKINLKLMDNQNKDQVTTLEVSVCDCEGAAGVCRKAQPVEAGLQIPAILGILGGILALLILILLLLLFLRRRAVVKEPLLPPEDDTRDNVYYYDEEGGGEEDQDFDLSQLHRGLDARPEVTRNDVAPTLMSVPRYLPRPANPDEIGNFIDENLKAADTDPTAPPYDSLLVFDYEGSGSEAASLSSLNSSESDKDQDYDYLNEWGNRFKKLADMYGGGEDD | Homo sapiens | Cell junction, adherens junction, Cell membrane, Endosome, Golgi apparatus, trans-Golgi network, Cytoplasm, Cell junction, desmosome | Tissue enhanced (parathyroid) | {'Ciliated cells': '119.1', 'Basal respiratory cells': '71.1', 'Club cells': '97.3', 'Ionocytes': '81.0', 'Mucus glandular cells': '155.0', 'Serous glandular cells': '67.8', 'Gastric mucus-secreting cells': '133.2', 'Proximal enterocytes': '140.9', 'Paneth cells': '125.1', 'Distal enterocytes': '307.5', 'Intestinal goblet cells': '173.5', 'Exocrine glandular cells': '-0.605', 'Basal prostatic cells': '68.3', 'Prostatic glandular cells': '186.7', 'Breast glandular cells': '0.773', 'Breast myoepithelial cells': '0.700', 'Glandular and luminal cells': '313.0', 'Secretory cells': '82.3', 'Basal keratinocytes': '102.5', 'Suprabasal keratinocytes': '162.6', 'Basal squamous epithelial cells': '51.0', 'Squamous epithelial cells': '106.9', 'Alveolar cells type 1': '0.437', 'Alveolar cells type 2': '0.706', 'Salivary duct cells': '95.9', 'Ductal cells': '0.541', 'Hepatocytes': '0.600', 'Cholangiocytes': '129.7', 'Proximal tubular cells': '0.042', 'Distal tubular cells': '0.0', 'Collecting duct cells': '143.9', 'Mesothelial cells': '0.799', 'Sertoli cells': '0.252', 'Granulosa cells': '12.9', 'Enteroendocrine cells': '92.4', 'Pancreatic endocrine cells': '78.1', 'Leydig cells': '0.264', 'Excitatory neurons': '0.7', 'Inhibitory neurons': '1.3', 'Cone photoreceptor cells': '0.0', 'Rod photoreceptor cells': '0.0', 'Bipolar cells': '0.2', 'Horizontal cells': '0.6', 'Astrocytes': '0.6', 'Oligodendrocyte precursor cells': '0.5', 'Oligodendrocytes': '29.9', 'Microglial cells': '0.9', 'Muller glia cells': '0.1', 'Schwann cells': '0.131', 'Spermatogonia': '0.392', 'Spermatocytes': '0.193', 'Early spermatids': '-0.217', 'Late spermatids': '-0.290', 'Oocytes': '16.9', 'Cytotrophoblasts': '119.2', 'Syncytiotrophoblasts': '45.0', 'Extravillous trophoblasts': '24.9', 'Endothelial cells': '6.1', 'Lymphatic endothelial cells': '0.4', 'Cardiomyocytes': '0.135', 'Skeletal myocytes': '0.107', 'Smooth muscle cells': '5.8', 'Adipocytes': '2.1', 'Melanocytes': '0.335', 'Fibroblasts': '6.5', 'Peritubular cells': '0.210', 'Endometrial stromal cells': '27.7', 'Ovarian stromal cells': '0.7', 'Undifferentiated cells': '101.6', 'T-cells': '2.9', 'B-cells': '4.4', 'Plasma cells': '6.1', 'Nk-cells': '0.0', 'Granulocytes': '8.4', 'Monocytes': '0.0', 'Macrophages': '6.0', 'Hofbauer cells': '4.3', 'Kupffer cells': '1.0', 'Dendritic cells': '5.9', 'Langerhans cells': '0.304', 'Erythroid cells': '0.036', 'Adipocytes (Subcutaneous)': '-0.081', 'Adipocytes (Visceral)': '-0.209', 'Breast glandular cells (progenitors)': '0.538', 'Adipocytes (Breast)': '-0.689', 'Colon enterocytes': '0.790', 'Colon enteroendocrine cells': '0.112', 'Enteric glia cells': '-0.048', 'Mitotic cells (Colon)': '0.299', 'Mitotic cells (Heart)': '0.120', 'Podocytes': '-0.118', 'Ascending Loop of Henle cells': '0.475', 'Intercalated cells': '0.212', 'Cholangiocyte': '0.090', 'NK-cells (Liver)': '-0.005', 'Respiratory ciliated cells': '-0.012', 'Mitotic cells (Lung)': '0.071', 'NK-cells (Lung)': '-0.266', 'B-cells (Lung)': '-0.296', 'Alpha cells': '0.270', 'Beta cells': '0.152', 'Prostate glandular cells': '0.764', 'Prostate basal glandular cells': '0.540', 'Urothelial cells': '0.205', 'Keratinocyte (other)': '0.510', 'Keratinocyte (granular)': '0.055', 'Hair cortex cells': '0.080', 'Inner root sheath cells': '0.131', 'Outer root sheath cells': '0.175', 'Sebaceous gland cells': '0.156', 'Eccrine sweat gland cells': '-0.207', 'Adipocytes (Skin)': '-0.244', 'Mitotic cells (Skin)': '0.442', 'Parietal cells': '0.654', 'Chief cells': '0.649', 'Gastric mucous cells': '0.781', 'Gastric enteroendocrine cells': '0.590', 'Mitotic cells (Stomach)': '0.445', 'Parafollicular cells': '0.173', 'Thyroid glandular cells': '0.865', 'Mitotic cells (Thyroid)': '-0.081', 'Adrenal cortex cells': '0.051', 'Adrenal medulla cells': '0.087', 'Mitotic cells (Adrenal gland)': '0.072', 'Minor salivary glandular cells': '0.371', 'Minor salivary gland ductal cells': '-0.142', 'Minor salivary gland basal cells': '0.582', 'Mitotic cells (Minor salivary gland)': '0.567', 'Adipocytes (Minor salivary gland)': '0.050', 'Somatotropes': '0.121', 'Lactotropes': '0.322', 'Gonadotropes': '0.330', 'Corticotropes': '0.180', 'Thyrotropes': '0.496', 'Undifferentiated cells (Pituitary gland)': '-0.108', 'Mitotic cells (Spleen)': '-0.228', 'Platelets': '-0.050', 'Erythrocytes': '-0.158', 'Hematopoietic stem cells': '-0.211', 'B-cells (Spleen)': '0.266', 'NK-cells (Spleen)': '0.309', 'Amygdala excitatory': '1.0', 'Cerebellar inhibitory': '0.9', 'Cge interneuron': '0.7', 'Deep-layer corticothalamic and 6b': '1.5', 'Deep-layer intratelencephalic': '0.7', 'Deep-layer near-projecting': '0.7', 'Eccentric medium spiny neuron': '0.6', 'Hippocampal ca1-3': '1.9', 'Hippocampal ca4': '1.2', 'Hippocampal dentate gyrus': '1.1', 'Lamp5-lhx6 and chandelier': '0.5', 'Lower rhombic lip': '0.8', 'Mammillary body': '0.6', 'Medium spiny neuron': '0.7', 'Mge interneuron': '1.7', 'Midbrain-derived inhibitory': '0.7', 'Miscellaneous': '0.9', 'Splatter': '3.8', 'Thalamic excitatory': '0.5', 'Upper rhombic lip': '0.8', 'Upper-layer intratelencephalic': '0.6', 'Astrocyte': '4.4', 'Bergmann glia': '0.2', 'Central nervous system macrophage': '0.6', 'Choroid plexus epithelial cell': '52.1', 'Committed oligodendrocyte precursor': '41.5', 'Ependymal cell': '4.8', 'Oligodendrocyte': '53.1', 'Oligodendrocyte precursor cell': '2.4', 'Endothelial cell': '0.7', 'Pericyte': '0.3', 'Vascular associated smooth muscle cell': '0.0', 'Fibroblast': '17.4', 'Leukocyte': '1.1', 'Basophil': '0.0', 'Eosinophil': '0.0', 'Neutrophil': '0.0', 'Classical monocyte': '0.0', 'Non-classical monocyte': '0.0', 'Intermediate monocyte': '0.0', 'T-reg': '2.3', 'GdT-cell': '0.0', 'MAIT T-cell': '0.0', 'Memory CD4 T-cell': '0.0', 'Naive CD4 T-cell': '0.1', 'Memory CD8 T-cell': '0.2', 'Naive CD8 T-cell': '0.3', 'Memory B-cell': '0.0', 'Naive B-cell': '0.1', 'Plasmacytoid DC': '46.6', 'Myeloid DC': '8.5', 'NK-cell': '0.1', 'Total PBMC': '0.7', 'Vd2 gdTCR': '0.0', 'Memory CD4 T-cell Th1\\/Th17': '0.1', 'Memory CD4 T-cell Th17': '0.2', 'Memory CD4 T-cell Th2': '2.9', 'Non-Vd2 gdTCR': '0.1', 'Memory CD4 T-cell Th1': '0.3', 'Memory CD4 T-cell TFH': '0.5', 'Terminal effector memory CD4 T-cell': '0.0', 'Central memory CD8 T-cell': '4.8', 'Effector memory CD8 T-cell': '0.0', 'Terminal effector memory CD8 T-cell': '0.6', 'Non-switched memory B-cell': '0.0', 'Plasmablast': '3.3', 'Switched memory B-cell': '0.0', 'Exhausted memory B-cell': '0.7', 'Progenitor cell': '2.3', 'Memory T-reg': '1.3', 'Naive CD4 T-cell activated': '0.3', 'Naive CD8 T-cell activated': '0.6', 'Naive T-reg': '0.1'} | 1O6S, 2O72, 2OMT, 2OMU, 2OMV, 2OMX, 2OMY, 2OMZ, 3FF7, 3FF8, 3L6X, 3L6Y, 4ZT1, 4ZTE, 6CXY, 6OLE, 6OLF, 6OLG, 6VEL, 7STZ, 8H62 | {'Adipose Tissue': 1.2125261088039867, 'Adrenal Gland': 0.1914223992248062, 'Bladder': 39.2033519047619, 'Blood': 1.340954264800861, 'Blood Vessel': 0.3121561692883895, 'Brain': 0.8550442199091597, 'Breast': 38.54918344226579, 'Cervix Uteri': 23.539115789473684, 'Colon': 43.41292142490372, 'Esophagus': 53.97513367404844, 'Fallopian Tube': 14.900277777777776, 'Heart': 0.119140469221835, 'Kidney': 25.040449438202245, 'Liver': 26.60802654867257, 'Lung': 35.447986366782004, 'Muscle': 0.1378936151930261, 'Nerve': 17.518468982229404, 'Ovary': 3.6515122222222223, 'Pancreas': 56.89676829268293, 'Pituitary': 24.68741660777385, 'Prostate': 61.279967346938776, 'Salivary Gland': 92.01685185185184, 'Skin': 79.77571720232172, 'Small Intestine': 71.7519320855615, 'Spleen': 10.061029045643156, 'Stomach': 58.07813805013927, 'Testis': 0.8144204986149585, 'Thyroid': 135.176797856049, 'Uterus': 1.442593943661972, 'Vagina': 86.52345512820513} | HOXC10 | MTCPRNVTPNSYAEPLAAPGGGERYSRSAGMYMQSGSDFNCGVMRGCGLAPSLSKRDEGSSPSLALNTYPSYLSQLDSWGDPKAAYRLEQPVGRPLSSCSYPPSVKEENVCCMYSAEKRAKSGPEAALYSHPLPESCLGEHEVPVPSYYRASPSYSALDKTPHCSGANDFEAPFEQRASLNPRAEHLESPQLGGKVSFPETPKSDSQTPSPNEIKTEQSLAGPKGSPSESEKERAKAADSSPDTSDNEAKEEIKAENTTGNWLTAKSGRKKRCPYTKHQTLELEKEFLFNMYLTRERRLEISKTINLTDRQVKIWFQNRRMKLKKMNRENRIRELTSNFNFT | Homo sapiens | Nucleus | Tissue enriched (skeletal) | {'Ciliated cells': '0.0', 'Basal respiratory cells': '0.0', 'Club cells': '0.0', 'Ionocytes': '0.0', 'Mucus glandular cells': '0.0', 'Serous glandular cells': '0.0', 'Gastric mucus-secreting cells': '0.0', 'Proximal enterocytes': '0.1', 'Paneth cells': '0.0', 'Distal enterocytes': '0.0', 'Intestinal goblet cells': '0.0', 'Exocrine glandular cells': '-0.234', 'Basal prostatic cells': '0.0', 'Prostatic glandular cells': '0.0', 'Breast glandular cells': '0.447', 'Breast myoepithelial cells': '0.463', 'Glandular and luminal cells': '0.0', 'Secretory cells': '0.0', 'Basal keratinocytes': '10.2', 'Suprabasal keratinocytes': '9.6', 'Basal squamous epithelial cells': '0.7', 'Squamous epithelial cells': '0.1', 'Alveolar cells type 1': '0.020', 'Alveolar cells type 2': '-0.098', 'Salivary duct cells': '0.0', 'Ductal cells': '0.099', 'Hepatocytes': '0.052', 'Cholangiocytes': '0.0', 'Proximal tubular cells': '0.159', 'Distal tubular cells': '27.7', 'Collecting duct cells': '17.5', 'Mesothelial cells': '0.021', 'Sertoli cells': '0.176', 'Granulosa cells': '2.8', 'Enteroendocrine cells': '0.0', 'Pancreatic endocrine cells': '0.0', 'Leydig cells': '0.167', 'Excitatory neurons': '0.0', 'Inhibitory neurons': '0.0', 'Cone photoreceptor cells': '0.0', 'Rod photoreceptor cells': '0.0', 'Bipolar cells': '0.0', 'Horizontal cells': '0.0', 'Astrocytes': '0.0', 'Oligodendrocyte precursor cells': '0.0', 'Oligodendrocytes': '0.0', 'Microglial cells': '0.0', 'Muller glia cells': '0.1', 'Schwann cells': '0.248', 'Spermatogonia': '0.225', 'Spermatocytes': '0.432', 'Early spermatids': '-0.086', 'Late spermatids': '-0.136', 'Oocytes': '0.0', 'Cytotrophoblasts': '0.0', 'Syncytiotrophoblasts': '0.0', 'Extravillous trophoblasts': '0.1', 'Endothelial cells': '0.4', 'Lymphatic endothelial cells': '0.0', 'Cardiomyocytes': '0.000', 'Skeletal myocytes': '-0.132', 'Smooth muscle cells': '5.6', 'Adipocytes': '0.6', 'Melanocytes': '0.050', 'Fibroblasts': '7.2', 'Peritubular cells': '0.016', 'Endometrial stromal cells': '0.9', 'Ovarian stromal cells': '4.6', 'Undifferentiated cells': '0.1', 'T-cells': '0.4', 'B-cells': '0.4', 'Plasma cells': '0.0', 'Nk-cells': '0.0', 'Granulocytes': '0.0', 'Monocytes': '0.0', 'Macrophages': '0.7', 'Hofbauer cells': '0.0', 'Kupffer cells': '0.0', 'Dendritic cells': '0.0', 'Langerhans cells': '0.088', 'Erythroid cells': '-0.045', 'Adipocytes (Subcutaneous)': '-0.210', 'Adipocytes (Visceral)': '-0.177', 'Breast glandular cells (progenitors)': '0.508', 'Adipocytes (Breast)': '-0.405', 'Colon enterocytes': '-0.007', 'Colon enteroendocrine cells': '0.026', 'Enteric glia cells': '0.173', 'Mitotic cells (Colon)': '0.011', 'Mitotic cells (Heart)': '0.045', 'Podocytes': '-0.014', 'Ascending Loop of Henle cells': '0.493', 'Intercalated cells': '0.010', 'Cholangiocyte': '0.043', 'NK-cells (Liver)': '0.036', 'Respiratory ciliated cells': '-0.014', 'Mitotic cells (Lung)': '-0.105', 'NK-cells (Lung)': '0.027', 'B-cells (Lung)': '0.058', 'Alpha cells': '0.063', 'Beta cells': '-0.016', 'Prostate glandular cells': '-0.254', 'Prostate basal glandular cells': '-0.323', 'Urothelial cells': '-0.254', 'Keratinocyte (other)': '-0.014', 'Keratinocyte (granular)': '-0.141', 'Hair cortex cells': '0.128', 'Inner root sheath cells': '0.150', 'Outer root sheath cells': '0.275', 'Sebaceous gland cells': '-0.005', 'Eccrine sweat gland cells': '0.418', 'Adipocytes (Skin)': '0.145', 'Mitotic cells (Skin)': '0.271', 'Parietal cells': '-0.030', 'Chief cells': '-0.033', 'Gastric mucous cells': '-0.069', 'Gastric enteroendocrine cells': '-0.030', 'Mitotic cells (Stomach)': 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monocyte': '0.0', 'Intermediate monocyte': '0.0', 'T-reg': '0.0', 'GdT-cell': '0.0', 'MAIT T-cell': '0.0', 'Memory CD4 T-cell': '0.0', 'Naive CD4 T-cell': '0.0', 'Memory CD8 T-cell': '0.0', 'Naive CD8 T-cell': '0.0', 'Memory B-cell': '0.0', 'Naive B-cell': '0.0', 'Plasmacytoid DC': '0.0', 'Myeloid DC': '0.0', 'NK-cell': '0.0', 'Total PBMC': '0.0', 'Vd2 gdTCR': '0.0', 'Memory CD4 T-cell Th1\\/Th17': '0.0', 'Memory CD4 T-cell Th17': '0.0', 'Memory CD4 T-cell Th2': '0.0', 'Non-Vd2 gdTCR': '0.0', 'Memory CD4 T-cell Th1': '0.0', 'Memory CD4 T-cell TFH': '0.0', 'Terminal effector memory CD4 T-cell': '0.0', 'Central memory CD8 T-cell': '0.0', 'Effector memory CD8 T-cell': '0.0', 'Terminal effector memory CD8 T-cell': '0.0', 'Non-switched memory B-cell': '0.0', 'Plasmablast': '0.0', 'Switched memory B-cell': '0.0', 'Exhausted memory B-cell': '0.0', 'Progenitor cell': '0.0', 'Memory T-reg': '0.0', 'Naive CD4 T-cell activated': '0.0', 'Naive CD8 T-cell activated': '0.0', 'Naive T-reg': '0.0'} | null | {'Adipose Tissue': 14.054818542358804, 'Adrenal Gland': 0.8364182558139535, 'Bladder': 1.4036333333333335, 'Blood': 0.1086186544671689, 'Blood Vessel': 24.98999456029963, 'Brain': 0.0454970022710068, 'Breast': 3.3948529411764703, 'Cervix Uteri': 1.6972157894736843, 'Colon': 0.4591807856225931, 'Esophagus': 0.1328764692041522, 'Fallopian Tube': 21.676717777777775, 'Heart': 0.0338635772357723, 'Kidney': 27.975876404494382, 'Liver': 0.0285249646017699, 'Lung': 0.1107369757785467, 'Muscle': 65.65803237858033, 'Nerve': 6.716636510500808, 'Ovary': 4.359101222222223, 'Pancreas': 0.0520476798780487, 'Pituitary': 0.0475809399293286, 'Prostate': 1.4719703673469389, 'Salivary Gland': 0.0354305555555555, 'Skin': 44.27386622443339, 'Small Intestine': 4.316685775401069, 'Spleen': 0.0417082572614107, 'Stomach': 0.0461333899721448, 'Testis': 2.776337950138504, 'Thyroid': 0.1062438376722817, 'Uterus': 5.149835985915493, 'Vagina': 2.6226684615384617} | [39.93, 46.46, 52.9, 44.21, 41.4, 39.93, 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Forms a ternary complex composed of ADAM10, CADH1 and EPHA4, | null | null | KLRG1, SPEF1, DLGAP5, AJAP1, RAPGEF2, RAB8B, PIP5K1C, PKP2, TRPV4, CTNNB1, CAV1, DDR1, TBC1D2, CTNNA1, JUP, CTNND1, PSEN1, LIMA1, CDH1, JUP, ADAM10, CADH1 , EPHA4, | null | null | null | null | Homodimer | null | 79.91949 | 0.474025 | 59.743538 | 0.826842 | 2,212 |
P12830 | Q9NZH5-2 | null | degron_data | CDH1 | MGPWSRSLSALLLLLQVSSWLCQEPEPCHPGFDAESYTFTVPRRHLERGRVLGRVNFEDCTGRQRTAYFSLDTRFKVGTDGVITVKRPLRFHNPQIHFLVYAWDSTYRKFSTKVTLNTVGHHHRPPPHQASVSGIQAELLTFPNSSPGLRRQKRDWVIPPISCPENEKGPFPKNLVQIKSNKDKEGKVFYSITGQGADTPPVGVFIIERETGWLKVTEPLDRERIATYTLFSHAVSSNGNAVEDPMEILITVTDQNDNKPEFTQEVFKGSVMEGALPGTSVMEVTATDADDDVNTYNAAIAYTILSQDPELPDKNMFTINRNTGVISVVTTGLDRESFPTYTLVVQAADLQGEGLSTTATAVITVTDTNDNPPIFNPTTYKGQVPENEANVVITTLKVTDADAPNTPAWEAVYTILNDDGGQFVVTTNPVNNDGILKTAKGLDFEAKQQYILHVAVTNVVPFEVSLTTSTATVTVDVLDVNEAPIFVPPEKRVEVSEDFGVGQEITSYTAQEPDTFMEQKITYRIWRDTANWLEINPDTGAISTRAELDREDFEHVKNSTYTALIIATDNGSPVATGTGTLLLILSDVNDNAPIPEPRTIFFCERNPKPQVINIIDADLPPNTSPFTAELTHGASANWTIQYNDPTQESIILKPKMALEVGDYKINLKLMDNQNKDQVTTLEVSVCDCEGAAGVCRKAQPVEAGLQIPAILGILGGILALLILILLLLLFLRRRAVVKEPLLPPEDDTRDNVYYYDEEGGGEEDQDFDLSQLHRGLDARPEVTRNDVAPTLMSVPRYLPRPANPDEIGNFIDENLKAADTDPTAPPYDSLLVFDYEGSGSEAASLSSLNSSESDKDQDYDYLNEWGNRFKKLADMYGGGEDD | Homo sapiens | Cell junction, adherens junction, Cell membrane, Endosome, Golgi apparatus, trans-Golgi network, Cytoplasm, Cell junction, desmosome | Tissue enhanced (parathyroid) | {'Ciliated cells': '119.1', 'Basal respiratory cells': '71.1', 'Club cells': '97.3', 'Ionocytes': '81.0', 'Mucus glandular cells': '155.0', 'Serous glandular cells': '67.8', 'Gastric mucus-secreting cells': '133.2', 'Proximal enterocytes': '140.9', 'Paneth cells': '125.1', 'Distal enterocytes': '307.5', 'Intestinal goblet cells': '173.5', 'Exocrine glandular cells': '-0.605', 'Basal prostatic cells': '68.3', 'Prostatic glandular cells': '186.7', 'Breast glandular cells': '0.773', 'Breast myoepithelial cells': '0.700', 'Glandular and luminal cells': '313.0', 'Secretory cells': '82.3', 'Basal keratinocytes': '102.5', 'Suprabasal keratinocytes': '162.6', 'Basal squamous epithelial cells': '51.0', 'Squamous epithelial cells': '106.9', 'Alveolar cells type 1': '0.437', 'Alveolar cells type 2': '0.706', 'Salivary duct cells': '95.9', 'Ductal cells': '0.541', 'Hepatocytes': '0.600', 'Cholangiocytes': '129.7', 'Proximal tubular cells': '0.042', 'Distal tubular cells': '0.0', 'Collecting duct cells': '143.9', 'Mesothelial cells': '0.799', 'Sertoli cells': '0.252', 'Granulosa cells': '12.9', 'Enteroendocrine cells': '92.4', 'Pancreatic endocrine cells': '78.1', 'Leydig cells': '0.264', 'Excitatory neurons': '0.7', 'Inhibitory neurons': '1.3', 'Cone photoreceptor cells': '0.0', 'Rod photoreceptor cells': '0.0', 'Bipolar cells': '0.2', 'Horizontal cells': '0.6', 'Astrocytes': '0.6', 'Oligodendrocyte precursor cells': '0.5', 'Oligodendrocytes': '29.9', 'Microglial cells': '0.9', 'Muller glia cells': '0.1', 'Schwann cells': '0.131', 'Spermatogonia': '0.392', 'Spermatocytes': '0.193', 'Early spermatids': '-0.217', 'Late spermatids': '-0.290', 'Oocytes': '16.9', 'Cytotrophoblasts': '119.2', 'Syncytiotrophoblasts': '45.0', 'Extravillous trophoblasts': '24.9', 'Endothelial cells': '6.1', 'Lymphatic endothelial cells': '0.4', 'Cardiomyocytes': '0.135', 'Skeletal myocytes': '0.107', 'Smooth muscle cells': '5.8', 'Adipocytes': '2.1', 'Melanocytes': '0.335', 'Fibroblasts': '6.5', 'Peritubular cells': '0.210', 'Endometrial stromal cells': '27.7', 'Ovarian stromal cells': '0.7', 'Undifferentiated cells': '101.6', 'T-cells': '2.9', 'B-cells': '4.4', 'Plasma cells': '6.1', 'Nk-cells': '0.0', 'Granulocytes': '8.4', 'Monocytes': '0.0', 'Macrophages': '6.0', 'Hofbauer cells': '4.3', 'Kupffer cells': '1.0', 'Dendritic cells': '5.9', 'Langerhans cells': '0.304', 'Erythroid cells': '0.036', 'Adipocytes (Subcutaneous)': '-0.081', 'Adipocytes (Visceral)': '-0.209', 'Breast glandular cells (progenitors)': '0.538', 'Adipocytes (Breast)': '-0.689', 'Colon enterocytes': '0.790', 'Colon enteroendocrine cells': '0.112', 'Enteric glia cells': '-0.048', 'Mitotic cells (Colon)': '0.299', 'Mitotic cells (Heart)': '0.120', 'Podocytes': '-0.118', 'Ascending Loop of Henle cells': '0.475', 'Intercalated cells': '0.212', 'Cholangiocyte': '0.090', 'NK-cells (Liver)': '-0.005', 'Respiratory ciliated cells': '-0.012', 'Mitotic cells (Lung)': '0.071', 'NK-cells (Lung)': '-0.266', 'B-cells (Lung)': '-0.296', 'Alpha cells': '0.270', 'Beta cells': '0.152', 'Prostate glandular cells': '0.764', 'Prostate basal glandular cells': '0.540', 'Urothelial cells': '0.205', 'Keratinocyte (other)': '0.510', 'Keratinocyte (granular)': '0.055', 'Hair cortex cells': '0.080', 'Inner root sheath cells': '0.131', 'Outer root sheath cells': '0.175', 'Sebaceous gland cells': '0.156', 'Eccrine sweat gland cells': '-0.207', 'Adipocytes (Skin)': '-0.244', 'Mitotic cells (Skin)': '0.442', 'Parietal cells': '0.654', 'Chief cells': '0.649', 'Gastric mucous cells': '0.781', 'Gastric enteroendocrine cells': '0.590', 'Mitotic cells (Stomach)': '0.445', 'Parafollicular cells': '0.173', 'Thyroid glandular cells': '0.865', 'Mitotic cells (Thyroid)': '-0.081', 'Adrenal cortex cells': '0.051', 'Adrenal medulla cells': '0.087', 'Mitotic cells (Adrenal gland)': '0.072', 'Minor salivary glandular cells': '0.371', 'Minor salivary gland ductal cells': '-0.142', 'Minor salivary gland basal cells': '0.582', 'Mitotic cells (Minor salivary gland)': '0.567', 'Adipocytes (Minor salivary gland)': '0.050', 'Somatotropes': '0.121', 'Lactotropes': '0.322', 'Gonadotropes': '0.330', 'Corticotropes': '0.180', 'Thyrotropes': '0.496', 'Undifferentiated cells (Pituitary gland)': '-0.108', 'Mitotic cells (Spleen)': '-0.228', 'Platelets': '-0.050', 'Erythrocytes': '-0.158', 'Hematopoietic stem cells': '-0.211', 'B-cells (Spleen)': '0.266', 'NK-cells (Spleen)': '0.309', 'Amygdala excitatory': '1.0', 'Cerebellar inhibitory': '0.9', 'Cge interneuron': '0.7', 'Deep-layer corticothalamic and 6b': '1.5', 'Deep-layer intratelencephalic': '0.7', 'Deep-layer near-projecting': '0.7', 'Eccentric medium spiny neuron': '0.6', 'Hippocampal ca1-3': '1.9', 'Hippocampal ca4': '1.2', 'Hippocampal dentate gyrus': '1.1', 'Lamp5-lhx6 and chandelier': '0.5', 'Lower rhombic lip': '0.8', 'Mammillary body': '0.6', 'Medium spiny neuron': '0.7', 'Mge interneuron': '1.7', 'Midbrain-derived inhibitory': '0.7', 'Miscellaneous': '0.9', 'Splatter': '3.8', 'Thalamic excitatory': '0.5', 'Upper rhombic lip': '0.8', 'Upper-layer intratelencephalic': '0.6', 'Astrocyte': '4.4', 'Bergmann glia': '0.2', 'Central nervous system macrophage': '0.6', 'Choroid plexus epithelial cell': '52.1', 'Committed oligodendrocyte precursor': '41.5', 'Ependymal cell': '4.8', 'Oligodendrocyte': '53.1', 'Oligodendrocyte precursor cell': '2.4', 'Endothelial cell': '0.7', 'Pericyte': '0.3', 'Vascular associated smooth muscle cell': '0.0', 'Fibroblast': '17.4', 'Leukocyte': '1.1', 'Basophil': '0.0', 'Eosinophil': '0.0', 'Neutrophil': '0.0', 'Classical monocyte': '0.0', 'Non-classical monocyte': '0.0', 'Intermediate monocyte': '0.0', 'T-reg': '2.3', 'GdT-cell': '0.0', 'MAIT T-cell': '0.0', 'Memory CD4 T-cell': '0.0', 'Naive CD4 T-cell': '0.1', 'Memory CD8 T-cell': '0.2', 'Naive CD8 T-cell': '0.3', 'Memory B-cell': '0.0', 'Naive B-cell': '0.1', 'Plasmacytoid DC': '46.6', 'Myeloid DC': '8.5', 'NK-cell': '0.1', 'Total PBMC': '0.7', 'Vd2 gdTCR': '0.0', 'Memory CD4 T-cell Th1\\/Th17': '0.1', 'Memory CD4 T-cell Th17': '0.2', 'Memory CD4 T-cell Th2': '2.9', 'Non-Vd2 gdTCR': '0.1', 'Memory CD4 T-cell Th1': '0.3', 'Memory CD4 T-cell TFH': '0.5', 'Terminal effector memory CD4 T-cell': '0.0', 'Central memory CD8 T-cell': '4.8', 'Effector memory CD8 T-cell': '0.0', 'Terminal effector memory CD8 T-cell': '0.6', 'Non-switched memory B-cell': '0.0', 'Plasmablast': '3.3', 'Switched memory B-cell': '0.0', 'Exhausted memory B-cell': '0.7', 'Progenitor cell': '2.3', 'Memory T-reg': '1.3', 'Naive CD4 T-cell activated': '0.3', 'Naive CD8 T-cell activated': '0.6', 'Naive T-reg': '0.1'} | 1O6S, 2O72, 2OMT, 2OMU, 2OMV, 2OMX, 2OMY, 2OMZ, 3FF7, 3FF8, 3L6X, 3L6Y, 4ZT1, 4ZTE, 6CXY, 6OLE, 6OLF, 6OLG, 6VEL, 7STZ, 8H62 | {'Adipose Tissue': 1.2125261088039867, 'Adrenal Gland': 0.1914223992248062, 'Bladder': 39.2033519047619, 'Blood': 1.340954264800861, 'Blood Vessel': 0.3121561692883895, 'Brain': 0.8550442199091597, 'Breast': 38.54918344226579, 'Cervix Uteri': 23.539115789473684, 'Colon': 43.41292142490372, 'Esophagus': 53.97513367404844, 'Fallopian Tube': 14.900277777777776, 'Heart': 0.119140469221835, 'Kidney': 25.040449438202245, 'Liver': 26.60802654867257, 'Lung': 35.447986366782004, 'Muscle': 0.1378936151930261, 'Nerve': 17.518468982229404, 'Ovary': 3.6515122222222223, 'Pancreas': 56.89676829268293, 'Pituitary': 24.68741660777385, 'Prostate': 61.279967346938776, 'Salivary Gland': 92.01685185185184, 'Skin': 79.77571720232172, 'Small Intestine': 71.7519320855615, 'Spleen': 10.061029045643156, 'Stomach': 58.07813805013927, 'Testis': 0.8144204986149585, 'Thyroid': 135.176797856049, 'Uterus': 1.442593943661972, 'Vagina': 86.52345512820513} | PTTG2 | MATLIYVDKEIGEPGTRVAAKDVLKLESRPSIKALDGISQVLTRRFGKTYDAPSALPKATRKALGTVNRATEKSVKTNGPRKQKQPSFSAKKMTEKTVKTKSSVPASDDAYPEIEKFFPFNLLDFESFDLPEERQIAHLPLSGVPLMILDEEGELEKLFQLGPPSPVKMPSPPWECNLFAVSFKHSVDPGC | Homo sapiens | null | Not found | {} | null | {'Adipose Tissue': 0.4639726328903655, 'Adrenal Gland': 0.0897329457364341, 'Bladder': 1.1418, 'Blood': 0.748422691065662, 'Blood Vessel': 1.9751588389513108, 'Brain': 0.4841600075700227, 'Breast': 0.3305101089324618, 'Cervix Uteri': 0.7931526315789474, 'Colon': 1.618507997432606, 'Esophagus': 0.8111101522491349, 'Fallopian Tube': 1.242748888888889, 'Heart': 0.6481920441347271, 'Kidney': 0.3338534831460674, 'Liver': 0.1867276548672566, 'Lung': 0.8233365051903114, 'Muscle': 0.5557330635118306, 'Nerve': 0.4343408885298869, 'Ovary': 0.4670455, 'Pancreas': 0.1599472865853658, 'Pituitary': 0.4033778798586572, 'Prostate': 0.6806202857142857, 'Salivary Gland': 0.1576929629629629, 'Skin': 0.1475455389718076, 'Small Intestine': 0.814641871657754, 'Spleen': 1.4785477178423236, 'Stomach': 0.547606991643454, 'Testis': 0.1705815789473684, 'Thyroid': 0.4332415467075038, 'Uterus': 1.848892253521127, 'Vagina': 0.5994922435897436} | [39.93, 46.46, 52.9, 44.21, 41.4, 39.93, 35.91, 38.61, 36.44, 36.25, 34.86, 32.82, 32.01, 32.75, 31.69, 35.64, 36.35, 34.66, 33.32, 32.71, 35.01, 30.17, 37.05, 36.53, 48.19, 58.22, 64.94, 73.22, 78.33, 82.63, 85.79, 89.39, 87.89, 85.58, 83.93, 89.1, 89.27, 90.66, 87.86, 86.2, 82.97, 72.75, 73.3, 76.44, 82.38, 82.41, 79.49, 86.6, 76.32, 85.48, 88.69, 84.35, 87.75, 90.57, 88.72, 89.46, 87.48, 85.3, 81.72, 79.46, 77.26, 69.01, 67.1, 62.83, 67.71, 74.96, 82.95, 86.74, 86.35, 86.49, 84.6, 85.99, 85.64, 87.19, 89.23, 89.3, 90.62, 84.21, 85.42, 83.34, 84.28, 89.8, 89.78, 87.53, 87.64, 85.98, 81.31, 80.85, 78.74, 80.15, 70.67, 69.91, 72.91, 77.13, 83.26, 84.67, 90.36, 89.7, 92.74, 89.99, 92.55, 88.84, 87.15, 83.78, 78.78, 81.48, 78.75, 84.94, 88.04, 89.37, 92.07, 91.77, 92.31, 91.07, 90.65, 87.61, 83.41, 78.8, 63.24, 54.89, 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0.63, 0.57, 0.15, 0.55, 0.66, 0.1, 0.38, 0.74, 0.65, 0.17, 0.43, 0.66, 0.41, 0.8, 0.75, 0.9, 0.93, 0.52, 0.76, 0.89, 0.87, 0.76, 0.92, 0.91, 0.75, 0.61, 0.96, 0.89, 0.73, 0.97, 0.68, 0.87, 0.55, 0.85, 0.77, 0.69, 0.76, 0.98, 0.83, 0.68, 0.82, 0.74, 0.65, 0.96, 0.93, 0.54, 0.64, 0.28, 0.54, 0.52, 0.16, 0.51, 0.88, 0.6, 0.4, 0.88, 0.95, 0.33, 0.56, 0.73, 0.39, 0.06, 0.61, 0.75, 0.47, 0.19, 0.87, 0.7, 0.97, 0.94, 0.97] | null | null | null | Component of an E-cadherin/ catenin adhesion complex composed of at least E-cadherin/CDH1, beta-catenin/CTNNB1 or gamma-catenin/JUP, and potentially alpha-catenin/CTNNA1. Forms a ternary complex composed of ADAM10, CADH1 and EPHA4, | null | null | KLRG1, SPEF1, DLGAP5, AJAP1, RAPGEF2, RAB8B, PIP5K1C, PKP2, TRPV4, CTNNB1, CAV1, DDR1, TBC1D2, CTNNA1, JUP, CTNND1, PSEN1, LIMA1, CDH1, JUP, ADAM10, CADH1 , EPHA4, | null | null | null | null | Homodimer | null | 79.91949 | 0.474025 | null | null | 2,730 |
P12830 | Q9P2P5 | null | degron_data | CDH1 | MGPWSRSLSALLLLLQVSSWLCQEPEPCHPGFDAESYTFTVPRRHLERGRVLGRVNFEDCTGRQRTAYFSLDTRFKVGTDGVITVKRPLRFHNPQIHFLVYAWDSTYRKFSTKVTLNTVGHHHRPPPHQASVSGIQAELLTFPNSSPGLRRQKRDWVIPPISCPENEKGPFPKNLVQIKSNKDKEGKVFYSITGQGADTPPVGVFIIERETGWLKVTEPLDRERIATYTLFSHAVSSNGNAVEDPMEILITVTDQNDNKPEFTQEVFKGSVMEGALPGTSVMEVTATDADDDVNTYNAAIAYTILSQDPELPDKNMFTINRNTGVISVVTTGLDRESFPTYTLVVQAADLQGEGLSTTATAVITVTDTNDNPPIFNPTTYKGQVPENEANVVITTLKVTDADAPNTPAWEAVYTILNDDGGQFVVTTNPVNNDGILKTAKGLDFEAKQQYILHVAVTNVVPFEVSLTTSTATVTVDVLDVNEAPIFVPPEKRVEVSEDFGVGQEITSYTAQEPDTFMEQKITYRIWRDTANWLEINPDTGAISTRAELDREDFEHVKNSTYTALIIATDNGSPVATGTGTLLLILSDVNDNAPIPEPRTIFFCERNPKPQVINIIDADLPPNTSPFTAELTHGASANWTIQYNDPTQESIILKPKMALEVGDYKINLKLMDNQNKDQVTTLEVSVCDCEGAAGVCRKAQPVEAGLQIPAILGILGGILALLILILLLLLFLRRRAVVKEPLLPPEDDTRDNVYYYDEEGGGEEDQDFDLSQLHRGLDARPEVTRNDVAPTLMSVPRYLPRPANPDEIGNFIDENLKAADTDPTAPPYDSLLVFDYEGSGSEAASLSSLNSSESDKDQDYDYLNEWGNRFKKLADMYGGGEDD | Homo sapiens | Cell junction, adherens junction, Cell membrane, Endosome, Golgi apparatus, trans-Golgi network, Cytoplasm, Cell junction, desmosome | Tissue enhanced (parathyroid) | {'Ciliated cells': '119.1', 'Basal respiratory cells': '71.1', 'Club cells': '97.3', 'Ionocytes': '81.0', 'Mucus glandular cells': '155.0', 'Serous glandular cells': '67.8', 'Gastric mucus-secreting cells': '133.2', 'Proximal enterocytes': '140.9', 'Paneth cells': '125.1', 'Distal enterocytes': '307.5', 'Intestinal goblet cells': '173.5', 'Exocrine glandular cells': '-0.605', 'Basal prostatic cells': '68.3', 'Prostatic glandular cells': '186.7', 'Breast glandular cells': '0.773', 'Breast myoepithelial cells': '0.700', 'Glandular and luminal cells': '313.0', 'Secretory cells': '82.3', 'Basal keratinocytes': '102.5', 'Suprabasal keratinocytes': '162.6', 'Basal squamous epithelial cells': '51.0', 'Squamous epithelial cells': '106.9', 'Alveolar cells type 1': '0.437', 'Alveolar cells type 2': '0.706', 'Salivary duct cells': '95.9', 'Ductal cells': '0.541', 'Hepatocytes': '0.600', 'Cholangiocytes': '129.7', 'Proximal tubular cells': '0.042', 'Distal tubular cells': '0.0', 'Collecting duct cells': '143.9', 'Mesothelial cells': '0.799', 'Sertoli cells': '0.252', 'Granulosa cells': '12.9', 'Enteroendocrine cells': '92.4', 'Pancreatic endocrine cells': '78.1', 'Leydig cells': '0.264', 'Excitatory neurons': '0.7', 'Inhibitory neurons': '1.3', 'Cone photoreceptor cells': '0.0', 'Rod photoreceptor cells': '0.0', 'Bipolar cells': '0.2', 'Horizontal cells': '0.6', 'Astrocytes': '0.6', 'Oligodendrocyte precursor cells': '0.5', 'Oligodendrocytes': '29.9', 'Microglial cells': '0.9', 'Muller glia cells': '0.1', 'Schwann cells': '0.131', 'Spermatogonia': '0.392', 'Spermatocytes': '0.193', 'Early spermatids': '-0.217', 'Late spermatids': '-0.290', 'Oocytes': '16.9', 'Cytotrophoblasts': '119.2', 'Syncytiotrophoblasts': '45.0', 'Extravillous trophoblasts': '24.9', 'Endothelial cells': '6.1', 'Lymphatic endothelial cells': '0.4', 'Cardiomyocytes': '0.135', 'Skeletal myocytes': '0.107', 'Smooth muscle cells': '5.8', 'Adipocytes': '2.1', 'Melanocytes': '0.335', 'Fibroblasts': '6.5', 'Peritubular cells': '0.210', 'Endometrial stromal cells': '27.7', 'Ovarian stromal cells': '0.7', 'Undifferentiated cells': '101.6', 'T-cells': '2.9', 'B-cells': '4.4', 'Plasma cells': '6.1', 'Nk-cells': '0.0', 'Granulocytes': '8.4', 'Monocytes': '0.0', 'Macrophages': '6.0', 'Hofbauer cells': '4.3', 'Kupffer cells': '1.0', 'Dendritic cells': '5.9', 'Langerhans cells': '0.304', 'Erythroid cells': '0.036', 'Adipocytes (Subcutaneous)': '-0.081', 'Adipocytes (Visceral)': '-0.209', 'Breast glandular cells (progenitors)': '0.538', 'Adipocytes (Breast)': '-0.689', 'Colon enterocytes': '0.790', 'Colon enteroendocrine cells': '0.112', 'Enteric glia cells': '-0.048', 'Mitotic cells (Colon)': '0.299', 'Mitotic cells (Heart)': '0.120', 'Podocytes': '-0.118', 'Ascending Loop of Henle cells': '0.475', 'Intercalated cells': '0.212', 'Cholangiocyte': '0.090', 'NK-cells (Liver)': '-0.005', 'Respiratory ciliated cells': '-0.012', 'Mitotic cells (Lung)': '0.071', 'NK-cells (Lung)': '-0.266', 'B-cells (Lung)': '-0.296', 'Alpha cells': '0.270', 'Beta cells': '0.152', 'Prostate glandular cells': '0.764', 'Prostate basal glandular cells': '0.540', 'Urothelial cells': '0.205', 'Keratinocyte (other)': '0.510', 'Keratinocyte (granular)': '0.055', 'Hair cortex cells': '0.080', 'Inner root sheath cells': '0.131', 'Outer root sheath cells': '0.175', 'Sebaceous gland cells': '0.156', 'Eccrine sweat gland cells': '-0.207', 'Adipocytes (Skin)': '-0.244', 'Mitotic cells (Skin)': '0.442', 'Parietal cells': '0.654', 'Chief cells': '0.649', 'Gastric mucous cells': '0.781', 'Gastric enteroendocrine cells': '0.590', 'Mitotic cells (Stomach)': '0.445', 'Parafollicular cells': '0.173', 'Thyroid glandular cells': '0.865', 'Mitotic cells (Thyroid)': '-0.081', 'Adrenal cortex cells': '0.051', 'Adrenal medulla cells': '0.087', 'Mitotic cells (Adrenal gland)': '0.072', 'Minor salivary glandular cells': '0.371', 'Minor salivary gland ductal cells': '-0.142', 'Minor salivary gland basal cells': '0.582', 'Mitotic cells (Minor salivary gland)': '0.567', 'Adipocytes (Minor salivary gland)': '0.050', 'Somatotropes': '0.121', 'Lactotropes': '0.322', 'Gonadotropes': '0.330', 'Corticotropes': '0.180', 'Thyrotropes': '0.496', 'Undifferentiated cells (Pituitary gland)': '-0.108', 'Mitotic cells (Spleen)': '-0.228', 'Platelets': '-0.050', 'Erythrocytes': '-0.158', 'Hematopoietic stem cells': '-0.211', 'B-cells (Spleen)': '0.266', 'NK-cells (Spleen)': '0.309', 'Amygdala excitatory': '1.0', 'Cerebellar inhibitory': '0.9', 'Cge interneuron': '0.7', 'Deep-layer corticothalamic and 6b': '1.5', 'Deep-layer intratelencephalic': '0.7', 'Deep-layer near-projecting': '0.7', 'Eccentric medium spiny neuron': '0.6', 'Hippocampal ca1-3': '1.9', 'Hippocampal ca4': '1.2', 'Hippocampal dentate gyrus': '1.1', 'Lamp5-lhx6 and chandelier': '0.5', 'Lower rhombic lip': '0.8', 'Mammillary body': '0.6', 'Medium spiny neuron': '0.7', 'Mge interneuron': '1.7', 'Midbrain-derived inhibitory': '0.7', 'Miscellaneous': '0.9', 'Splatter': '3.8', 'Thalamic excitatory': '0.5', 'Upper rhombic lip': '0.8', 'Upper-layer intratelencephalic': '0.6', 'Astrocyte': '4.4', 'Bergmann glia': '0.2', 'Central nervous system macrophage': '0.6', 'Choroid plexus epithelial cell': '52.1', 'Committed oligodendrocyte precursor': '41.5', 'Ependymal cell': '4.8', 'Oligodendrocyte': '53.1', 'Oligodendrocyte precursor cell': '2.4', 'Endothelial cell': '0.7', 'Pericyte': '0.3', 'Vascular associated smooth muscle cell': '0.0', 'Fibroblast': '17.4', 'Leukocyte': '1.1', 'Basophil': '0.0', 'Eosinophil': '0.0', 'Neutrophil': '0.0', 'Classical monocyte': '0.0', 'Non-classical monocyte': '0.0', 'Intermediate monocyte': '0.0', 'T-reg': '2.3', 'GdT-cell': '0.0', 'MAIT T-cell': '0.0', 'Memory CD4 T-cell': '0.0', 'Naive CD4 T-cell': '0.1', 'Memory CD8 T-cell': '0.2', 'Naive CD8 T-cell': '0.3', 'Memory B-cell': '0.0', 'Naive B-cell': '0.1', 'Plasmacytoid DC': '46.6', 'Myeloid DC': '8.5', 'NK-cell': '0.1', 'Total PBMC': '0.7', 'Vd2 gdTCR': '0.0', 'Memory CD4 T-cell Th1\\/Th17': '0.1', 'Memory CD4 T-cell Th17': '0.2', 'Memory CD4 T-cell Th2': '2.9', 'Non-Vd2 gdTCR': '0.1', 'Memory CD4 T-cell Th1': '0.3', 'Memory CD4 T-cell TFH': '0.5', 'Terminal effector memory CD4 T-cell': '0.0', 'Central memory CD8 T-cell': '4.8', 'Effector memory CD8 T-cell': '0.0', 'Terminal effector memory CD8 T-cell': '0.6', 'Non-switched memory B-cell': '0.0', 'Plasmablast': '3.3', 'Switched memory B-cell': '0.0', 'Exhausted memory B-cell': '0.7', 'Progenitor cell': '2.3', 'Memory T-reg': '1.3', 'Naive CD4 T-cell activated': '0.3', 'Naive CD8 T-cell activated': '0.6', 'Naive T-reg': '0.1'} | 1O6S, 2O72, 2OMT, 2OMU, 2OMV, 2OMX, 2OMY, 2OMZ, 3FF7, 3FF8, 3L6X, 3L6Y, 4ZT1, 4ZTE, 6CXY, 6OLE, 6OLF, 6OLG, 6VEL, 7STZ, 8H62 | {'Adipose Tissue': 1.2125261088039867, 'Adrenal Gland': 0.1914223992248062, 'Bladder': 39.2033519047619, 'Blood': 1.340954264800861, 'Blood Vessel': 0.3121561692883895, 'Brain': 0.8550442199091597, 'Breast': 38.54918344226579, 'Cervix Uteri': 23.539115789473684, 'Colon': 43.41292142490372, 'Esophagus': 53.97513367404844, 'Fallopian Tube': 14.900277777777776, 'Heart': 0.119140469221835, 'Kidney': 25.040449438202245, 'Liver': 26.60802654867257, 'Lung': 35.447986366782004, 'Muscle': 0.1378936151930261, 'Nerve': 17.518468982229404, 'Ovary': 3.6515122222222223, 'Pancreas': 56.89676829268293, 'Pituitary': 24.68741660777385, 'Prostate': 61.279967346938776, 'Salivary Gland': 92.01685185185184, 'Skin': 79.77571720232172, 'Small Intestine': 71.7519320855615, 'Spleen': 10.061029045643156, 'Stomach': 58.07813805013927, 'Testis': 0.8144204986149585, 'Thyroid': 135.176797856049, 'Uterus': 1.442593943661972, 'Vagina': 86.52345512820513} | HECW2 | MASSAREHLLFVRRRNPQMRYTLSPENLQSLAAQSSMPENMTLQRANSDTDLVTSESRSSLTASMYEYTLGQAQNLIIFWDIKEEVDPSDWIGLYHIDENSPANFWDSKNRGVTGTQKGQIVWRIEPGPYFMEPEIKICFKYYHGISGALRATTPCITVKNPAVMMGAEGMEGGASGNLHSRKLVSFTLSDLRAVGLKKGMFFNPDPYLKMSIQPGKKSSFPTCAHHGQERRSTIISNTTNPIWHREKYSFFALLTDVLEIEIKDKFAKSRPIIKRFLGKLTIPVQRLLERQAIGDQMLSYNLGRRLPADHVSGYLQFKVEVTSSVHEDASPEAVGTILGVNSVNGDLGSPSDDEDMPGSHHDSQVCSNGPVSEDSAADGTPKHSFRTSSTLEIDTEELTSTSSRTSPPRGRQDSLNDYLDAIEHNGHSRPGTATCSERSMGASPKLRSSFPTDTRLNAMLHIDSDEEDHEFQQDLGYPSSLEEEGGLIMFSRASRADDGSLTSQTKLEDNPVENEEASTHEAASFEDKPENLPELAESSLPAGPAPEEGEGGPEPQPSADQGSAELCGSQEVDQPTSGADTGTSDASGGSRRAVSETESLDQGSEPSQVSSETEPSDPARTESVSEASTRPEGESDLECADSSCNESVTTQLSSVDTRCSSLESARFPETPAFSSQEEEDGACAAEPTSSGPAEGSQESVCTAGSLPVVQVPSGEDEGPGAESATVPDQEELGEVWQRRGSLEGAAAAAESPPQEEGSAGEAQGTCEGATAQEEGATGGSQANGHQPLRSLPSVRQDVSRYQRVDEALPPNWEARIDSHGRIFYVDHVNRTTTWQRPTAPPAPQVLQRSNSIQQMEQLNRRYQSIRRTMTNERPEENTNAIDGAGEEADFHQASADFRRENILPHSTSRSRITLLLQSPPVKFLISPEFFTVLHSNPSAYRMFTNNTCLKHMITKVRRDTHHFERYQHNRDLVGFLNMFANKQLELPRGWEMKHDHQGKAFFVDHNSRTTTFIDPRLPLQSSRPTSALVHRQHLTRQRSHSAGEVGEDSRHAGPPVLPRPSSTFNTVSRPQYQDMVPVAYNDKIVAFLRQPNIFEILQERQPDLTRNHSLREKIQFIRTEGTPGLVRLSSDADLVMLLSLFEEEIMSYVPPHALLHPSYCQSPRGSPVSSPQNSPGTQRANARAPAPYKRDFEAKLRNFYRKLETKGYGQGPGKLKLIIRRDHLLEDAFNQIMGYSRKDLQRNKLYVTFVGEEGLDYSGPSREFFFLVSRELFNPYYGLFEYSANDTYTVQISPMSAFVDNHHEWFRFSGRILGLALIHQYLLDAFFTRPFYKALLRILCDLSDLEYLDEEFHQSLQWMKDNDIHDILDLTFTVNEEVFGQITERELKPGGANIPVTEKNKKEYIERMVKWRIERGVVQQTESLVRGFYEVVDARLVSVFDARELELVIAGTAEIDLSDWRNNTEYRGGYHDNHIVIRWFWAAVERFNNEQRLRLLQFVTGTSSIPYEGFASLRGSNGPRRFCVEKWGKITALPRAHTCFNRLDLPPYPSFSMLYEKLLTAVEETSTFGLE | Homo sapiens | Cytoplasm, Cytoplasm, cytoskeleton, spindle | Low tissue specificity | {'Ciliated cells': '2.5', 'Basal respiratory cells': '0.1', 'Club cells': '2.5', 'Ionocytes': '0.0', 'Mucus glandular cells': '0.5', 'Serous glandular cells': '3.2', 'Gastric mucus-secreting cells': '0.0', 'Proximal enterocytes': '0.1', 'Paneth cells': '0.0', 'Distal enterocytes': '0.5', 'Intestinal goblet cells': '0.0', 'Exocrine glandular cells': '-0.170', 'Basal prostatic cells': '0.3', 'Prostatic glandular cells': '0.1', 'Breast glandular cells': '-0.205', 'Breast myoepithelial cells': '-0.214', 'Glandular and luminal cells': '0.3', 'Secretory cells': '1.9', 'Basal keratinocytes': '2.4', 'Suprabasal keratinocytes': '5.0', 'Basal squamous epithelial cells': '5.8', 'Squamous epithelial cells': '11.4', 'Alveolar cells type 1': '0.380', 'Alveolar cells type 2': '-0.124', 'Salivary duct cells': '2.4', 'Ductal cells': '0.414', 'Hepatocytes': '0.488', 'Cholangiocytes': '0.0', 'Proximal tubular cells': '0.076', 'Distal tubular cells': '0.0', 'Collecting duct cells': '0.0', 'Mesothelial cells': '-0.093', 'Sertoli cells': '0.470', 'Granulosa cells': '7.5', 'Enteroendocrine cells': '9.2', 'Pancreatic endocrine cells': '1.7', 'Leydig cells': '0.427', 'Excitatory neurons': '320.2', 'Inhibitory neurons': '359.4', 'Cone photoreceptor cells': '0.0', 'Rod photoreceptor cells': '1.1', 'Bipolar cells': '13.3', 'Horizontal cells': '21.4', 'Astrocytes': '12.1', 'Oligodendrocyte precursor cells': '134.4', 'Oligodendrocytes': '428.7', 'Microglial cells': '13.4', 'Muller glia cells': '15.1', 'Schwann cells': '0.230', 'Spermatogonia': '0.697', 'Spermatocytes': '0.465', 'Early spermatids': '-0.177', 'Late spermatids': '-0.432', 'Oocytes': '1.5', 'Cytotrophoblasts': '0.2', 'Syncytiotrophoblasts': '0.3', 'Extravillous trophoblasts': '0.5', 'Endothelial cells': '43.1', 'Lymphatic endothelial cells': '42.2', 'Cardiomyocytes': '0.591', 'Skeletal myocytes': '0.125', 'Smooth muscle cells': '3.2', 'Adipocytes': '51.6', 'Melanocytes': '0.056', 'Fibroblasts': '29.7', 'Peritubular cells': '0.384', 'Endometrial stromal cells': '1.5', 'Ovarian stromal cells': '0.4', 'Undifferentiated cells': '0.0', 'T-cells': '2.0', 'B-cells': '3.7', 'Plasma cells': '3.0', 'Nk-cells': '0.4', 'Granulocytes': '0.7', 'Monocytes': '5.0', 'Macrophages': '1.8', 'Hofbauer cells': '0.3', 'Kupffer cells': '9.9', 'Dendritic cells': '0.0', 'Langerhans cells': '0.131', 'Erythroid cells': '-0.125', 'Adipocytes (Subcutaneous)': '0.159', 'Adipocytes (Visceral)': '0.084', 'Breast glandular cells (progenitors)': '-0.137', 'Adipocytes (Breast)': '0.354', 'Colon enterocytes': '0.109', 'Colon enteroendocrine cells': '0.387', 'Enteric glia cells': '0.304', 'Mitotic cells (Colon)': '0.174', 'Mitotic cells (Heart)': '0.414', 'Podocytes': '0.246', 'Ascending Loop of Henle cells': '0.179', 'Intercalated cells': '0.213', 'Cholangiocyte': '0.327', 'NK-cells (Liver)': '-0.117', 'Respiratory ciliated cells': '-0.035', 'Mitotic cells (Lung)': '-0.077', 'NK-cells (Lung)': '0.401', 'B-cells (Lung)': '-0.028', 'Alpha cells': '0.319', 'Beta cells': '0.193', 'Prostate glandular cells': '0.116', 'Prostate basal glandular cells': '0.290', 'Urothelial cells': '0.222', 'Keratinocyte (other)': '-0.291', 'Keratinocyte (granular)': '-0.284', 'Hair cortex cells': '0.404', 'Inner root sheath cells': '0.434', 'Outer root sheath cells': '0.593', 'Sebaceous gland cells': '0.272', 'Eccrine sweat gland cells': '0.520', 'Adipocytes (Skin)': '0.341', 'Mitotic cells (Skin)': '0.261', 'Parietal cells': '0.099', 'Chief cells': '0.075', 'Gastric mucous cells': '0.148', 'Gastric enteroendocrine cells': '0.246', 'Mitotic cells (Stomach)': '0.219', 'Parafollicular cells': '0.054', 'Thyroid glandular cells': '0.291', 'Mitotic cells (Thyroid)': '0.033', 'Adrenal cortex cells': '0.078', 'Adrenal medulla cells': '0.147', 'Mitotic cells (Adrenal gland)': '-0.009', 'Minor salivary glandular cells': '-0.264', 'Minor salivary gland ductal cells': '-0.195', 'Minor salivary gland basal cells': '0.551', 'Mitotic cells (Minor salivary gland)': '0.575', 'Adipocytes (Minor salivary gland)': '0.202', 'Somatotropes': '0.122', 'Lactotropes': '0.374', 'Gonadotropes': '0.224', 'Corticotropes': '-0.053', 'Thyrotropes': '0.364', 'Undifferentiated cells (Pituitary gland)': '0.159', 'Mitotic cells (Spleen)': '-0.157', 'Platelets': '0.132', 'Erythrocytes': '-0.006', 'Hematopoietic stem cells': '-0.129', 'B-cells (Spleen)': '0.035', 'NK-cells (Spleen)': '0.253', 'Amygdala excitatory': '398.7', 'Cerebellar inhibitory': '391.8', 'Cge interneuron': '436.8', 'Deep-layer corticothalamic and 6b': '682.5', 'Deep-layer intratelencephalic': '480.4', 'Deep-layer near-projecting': '497.4', 'Eccentric medium spiny neuron': '518.3', 'Hippocampal ca1-3': '342.6', 'Hippocampal ca4': '322.8', 'Hippocampal dentate gyrus': '552.0', 'Lamp5-lhx6 and chandelier': '710.9', 'Lower rhombic lip': '450.6', 'Mammillary body': '461.3', 'Medium spiny neuron': '388.6', 'Mge interneuron': '441.2', 'Midbrain-derived inhibitory': '27.6', 'Miscellaneous': '494.0', 'Splatter': '328.3', 'Thalamic excitatory': '351.7', 'Upper rhombic lip': '453.8', 'Upper-layer intratelencephalic': '603.4', 'Astrocyte': '17.3', 'Bergmann glia': '3.6', 'Central nervous system macrophage': '9.6', 'Choroid plexus epithelial cell': '30.9', 'Committed oligodendrocyte precursor': '251.8', 'Ependymal cell': '163.2', 'Oligodendrocyte': '727.3', 'Oligodendrocyte precursor cell': '243.5', 'Endothelial cell': '81.8', 'Pericyte': '8.1', 'Vascular associated smooth muscle cell': '36.9', 'Fibroblast': '42.3', 'Leukocyte': '15.5', 'Basophil': '0.8', 'Eosinophil': '0.8', 'Neutrophil': '21.3', 'Classical monocyte': '0.2', 'Non-classical monocyte': '2.0', 'Intermediate monocyte': '3.5', 'T-reg': '0.2', 'GdT-cell': '0.0', 'MAIT T-cell': '0.2', 'Memory CD4 T-cell': '0.0', 'Naive CD4 T-cell': '0.1', 'Memory CD8 T-cell': '0.0', 'Naive CD8 T-cell': '0.0', 'Memory B-cell': '0.4', 'Naive B-cell': '0.4', 'Plasmacytoid DC': '0.2', 'Myeloid DC': '1.0', 'NK-cell': '0.0', 'Total PBMC': '0.8', 'Vd2 gdTCR': '0.2', 'Memory CD4 T-cell Th1\\/Th17': '0.1', 'Memory CD4 T-cell Th17': '0.2', 'Memory CD4 T-cell Th2': '0.4', 'Non-Vd2 gdTCR': '0.3', 'Memory CD4 T-cell Th1': '0.1', 'Memory CD4 T-cell TFH': '0.3', 'Terminal effector memory CD4 T-cell': '0.1', 'Central memory CD8 T-cell': '0.2', 'Effector memory CD8 T-cell': '0.3', 'Terminal effector memory CD8 T-cell': '0.2', 'Non-switched memory B-cell': '0.2', 'Plasmablast': '0.3', 'Switched memory B-cell': '0.4', 'Exhausted memory B-cell': '0.3', 'Progenitor cell': '0.2', 'Memory T-reg': '0.8', 'Naive CD4 T-cell activated': '5.5', 'Naive CD8 T-cell activated': '1.8', 'Naive T-reg': '0.7'} | 2LFE | {'Adipose Tissue': 3.680218853820598, 'Adrenal Gland': 1.8355627906976744, 'Bladder': 0.8448619047619048, 'Blood': 1.4191076953713673, 'Blood Vessel': 2.275656059925094, 'Brain': 4.517491218773656, 'Breast': 3.451143790849674, 'Cervix Uteri': 1.9485526315789472, 'Colon': 0.6536988960205392, 'Esophagus': 1.4922570934256054, 'Fallopian Tube': 1.2434555555555555, 'Heart': 3.034834030197445, 'Kidney': 1.4114966292134832, 'Liver': 0.8818253097345132, 'Lung': 17.315515570934256, 'Muscle': 0.3550280946450809, 'Nerve': 2.1410294022617125, 'Ovary': 0.7675848888888889, 'Pancreas': 0.4490132317073171, 'Pituitary': 2.886590106007067, 'Prostate': 0.9256834693877553, 'Salivary Gland': 1.1903524691358025, 'Skin': 1.4106940298507462, 'Small Intestine': 1.2177085561497327, 'Spleen': 8.482506224066391, 'Stomach': 0.7660788300835654, 'Testis': 3.190506925207756, 'Thyroid': 7.12176110260337, 'Uterus': 1.627284718309859, 'Vagina': 1.831648076923077} | [39.93, 46.46, 52.9, 44.21, 41.4, 39.93, 35.91, 38.61, 36.44, 36.25, 34.86, 32.82, 32.01, 32.75, 31.69, 35.64, 36.35, 34.66, 33.32, 32.71, 35.01, 30.17, 37.05, 36.53, 48.19, 58.22, 64.94, 73.22, 78.33, 82.63, 85.79, 89.39, 87.89, 85.58, 83.93, 89.1, 89.27, 90.66, 87.86, 86.2, 82.97, 72.75, 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Forms a ternary complex composed of ADAM10, CADH1 and EPHA4, | null | null | KLRG1, SPEF1, DLGAP5, AJAP1, RAPGEF2, RAB8B, PIP5K1C, PKP2, TRPV4, CTNNB1, CAV1, DDR1, TBC1D2, CTNNA1, JUP, CTNND1, PSEN1, LIMA1, CDH1, JUP, ADAM10, CADH1 , EPHA4, | null | null | null | null | Homodimer | null | 79.91949 | 0.474025 | 60.550261 | 0.601737 | 177 |
P12830 | Q9UKT4 | null | degron_data | CDH1 | MGPWSRSLSALLLLLQVSSWLCQEPEPCHPGFDAESYTFTVPRRHLERGRVLGRVNFEDCTGRQRTAYFSLDTRFKVGTDGVITVKRPLRFHNPQIHFLVYAWDSTYRKFSTKVTLNTVGHHHRPPPHQASVSGIQAELLTFPNSSPGLRRQKRDWVIPPISCPENEKGPFPKNLVQIKSNKDKEGKVFYSITGQGADTPPVGVFIIERETGWLKVTEPLDRERIATYTLFSHAVSSNGNAVEDPMEILITVTDQNDNKPEFTQEVFKGSVMEGALPGTSVMEVTATDADDDVNTYNAAIAYTILSQDPELPDKNMFTINRNTGVISVVTTGLDRESFPTYTLVVQAADLQGEGLSTTATAVITVTDTNDNPPIFNPTTYKGQVPENEANVVITTLKVTDADAPNTPAWEAVYTILNDDGGQFVVTTNPVNNDGILKTAKGLDFEAKQQYILHVAVTNVVPFEVSLTTSTATVTVDVLDVNEAPIFVPPEKRVEVSEDFGVGQEITSYTAQEPDTFMEQKITYRIWRDTANWLEINPDTGAISTRAELDREDFEHVKNSTYTALIIATDNGSPVATGTGTLLLILSDVNDNAPIPEPRTIFFCERNPKPQVINIIDADLPPNTSPFTAELTHGASANWTIQYNDPTQESIILKPKMALEVGDYKINLKLMDNQNKDQVTTLEVSVCDCEGAAGVCRKAQPVEAGLQIPAILGILGGILALLILILLLLLFLRRRAVVKEPLLPPEDDTRDNVYYYDEEGGGEEDQDFDLSQLHRGLDARPEVTRNDVAPTLMSVPRYLPRPANPDEIGNFIDENLKAADTDPTAPPYDSLLVFDYEGSGSEAASLSSLNSSESDKDQDYDYLNEWGNRFKKLADMYGGGEDD | Homo sapiens | Cell junction, adherens junction, Cell membrane, Endosome, Golgi apparatus, trans-Golgi network, Cytoplasm, Cell junction, desmosome | Tissue enhanced (parathyroid) | {'Ciliated cells': '119.1', 'Basal respiratory cells': '71.1', 'Club cells': '97.3', 'Ionocytes': '81.0', 'Mucus glandular cells': '155.0', 'Serous glandular cells': '67.8', 'Gastric mucus-secreting cells': '133.2', 'Proximal enterocytes': '140.9', 'Paneth cells': '125.1', 'Distal enterocytes': '307.5', 'Intestinal goblet cells': '173.5', 'Exocrine glandular cells': '-0.605', 'Basal prostatic cells': '68.3', 'Prostatic glandular cells': '186.7', 'Breast glandular cells': '0.773', 'Breast myoepithelial cells': '0.700', 'Glandular and luminal cells': '313.0', 'Secretory cells': '82.3', 'Basal keratinocytes': '102.5', 'Suprabasal keratinocytes': '162.6', 'Basal squamous epithelial cells': '51.0', 'Squamous epithelial cells': '106.9', 'Alveolar cells type 1': '0.437', 'Alveolar cells type 2': '0.706', 'Salivary duct cells': '95.9', 'Ductal cells': '0.541', 'Hepatocytes': '0.600', 'Cholangiocytes': '129.7', 'Proximal tubular cells': '0.042', 'Distal tubular cells': '0.0', 'Collecting duct cells': '143.9', 'Mesothelial cells': '0.799', 'Sertoli cells': '0.252', 'Granulosa cells': '12.9', 'Enteroendocrine cells': '92.4', 'Pancreatic endocrine cells': '78.1', 'Leydig cells': '0.264', 'Excitatory neurons': '0.7', 'Inhibitory neurons': '1.3', 'Cone photoreceptor cells': '0.0', 'Rod photoreceptor cells': '0.0', 'Bipolar cells': '0.2', 'Horizontal cells': '0.6', 'Astrocytes': '0.6', 'Oligodendrocyte precursor cells': '0.5', 'Oligodendrocytes': '29.9', 'Microglial cells': '0.9', 'Muller glia cells': '0.1', 'Schwann cells': '0.131', 'Spermatogonia': '0.392', 'Spermatocytes': '0.193', 'Early spermatids': '-0.217', 'Late spermatids': '-0.290', 'Oocytes': '16.9', 'Cytotrophoblasts': '119.2', 'Syncytiotrophoblasts': '45.0', 'Extravillous trophoblasts': '24.9', 'Endothelial cells': '6.1', 'Lymphatic endothelial cells': '0.4', 'Cardiomyocytes': '0.135', 'Skeletal myocytes': '0.107', 'Smooth muscle cells': '5.8', 'Adipocytes': '2.1', 'Melanocytes': '0.335', 'Fibroblasts': '6.5', 'Peritubular cells': '0.210', 'Endometrial stromal cells': '27.7', 'Ovarian stromal cells': '0.7', 'Undifferentiated cells': '101.6', 'T-cells': '2.9', 'B-cells': '4.4', 'Plasma cells': '6.1', 'Nk-cells': '0.0', 'Granulocytes': '8.4', 'Monocytes': '0.0', 'Macrophages': '6.0', 'Hofbauer cells': '4.3', 'Kupffer cells': '1.0', 'Dendritic cells': '5.9', 'Langerhans cells': '0.304', 'Erythroid cells': '0.036', 'Adipocytes (Subcutaneous)': '-0.081', 'Adipocytes (Visceral)': '-0.209', 'Breast glandular cells (progenitors)': '0.538', 'Adipocytes (Breast)': '-0.689', 'Colon enterocytes': '0.790', 'Colon enteroendocrine cells': '0.112', 'Enteric glia cells': '-0.048', 'Mitotic cells (Colon)': '0.299', 'Mitotic cells (Heart)': '0.120', 'Podocytes': '-0.118', 'Ascending Loop of Henle cells': '0.475', 'Intercalated cells': '0.212', 'Cholangiocyte': '0.090', 'NK-cells (Liver)': '-0.005', 'Respiratory ciliated cells': '-0.012', 'Mitotic cells (Lung)': '0.071', 'NK-cells (Lung)': '-0.266', 'B-cells (Lung)': '-0.296', 'Alpha cells': '0.270', 'Beta cells': '0.152', 'Prostate glandular cells': '0.764', 'Prostate basal glandular cells': '0.540', 'Urothelial cells': '0.205', 'Keratinocyte (other)': '0.510', 'Keratinocyte (granular)': '0.055', 'Hair cortex cells': '0.080', 'Inner root sheath cells': '0.131', 'Outer root sheath cells': '0.175', 'Sebaceous gland cells': '0.156', 'Eccrine sweat gland cells': '-0.207', 'Adipocytes (Skin)': '-0.244', 'Mitotic cells (Skin)': '0.442', 'Parietal cells': '0.654', 'Chief cells': '0.649', 'Gastric mucous cells': '0.781', 'Gastric enteroendocrine cells': '0.590', 'Mitotic cells (Stomach)': '0.445', 'Parafollicular cells': '0.173', 'Thyroid glandular cells': '0.865', 'Mitotic cells (Thyroid)': '-0.081', 'Adrenal cortex cells': '0.051', 'Adrenal medulla cells': '0.087', 'Mitotic cells (Adrenal gland)': '0.072', 'Minor salivary glandular cells': '0.371', 'Minor salivary gland ductal cells': '-0.142', 'Minor salivary gland basal cells': '0.582', 'Mitotic cells (Minor salivary gland)': '0.567', 'Adipocytes (Minor salivary gland)': '0.050', 'Somatotropes': '0.121', 'Lactotropes': '0.322', 'Gonadotropes': '0.330', 'Corticotropes': '0.180', 'Thyrotropes': '0.496', 'Undifferentiated cells (Pituitary gland)': '-0.108', 'Mitotic cells (Spleen)': '-0.228', 'Platelets': '-0.050', 'Erythrocytes': '-0.158', 'Hematopoietic stem cells': '-0.211', 'B-cells (Spleen)': '0.266', 'NK-cells (Spleen)': '0.309', 'Amygdala excitatory': '1.0', 'Cerebellar inhibitory': '0.9', 'Cge interneuron': '0.7', 'Deep-layer corticothalamic and 6b': '1.5', 'Deep-layer intratelencephalic': '0.7', 'Deep-layer near-projecting': '0.7', 'Eccentric medium spiny neuron': '0.6', 'Hippocampal ca1-3': '1.9', 'Hippocampal ca4': '1.2', 'Hippocampal dentate gyrus': '1.1', 'Lamp5-lhx6 and chandelier': '0.5', 'Lower rhombic lip': '0.8', 'Mammillary body': '0.6', 'Medium spiny neuron': '0.7', 'Mge interneuron': '1.7', 'Midbrain-derived inhibitory': '0.7', 'Miscellaneous': '0.9', 'Splatter': '3.8', 'Thalamic excitatory': '0.5', 'Upper rhombic lip': '0.8', 'Upper-layer intratelencephalic': '0.6', 'Astrocyte': '4.4', 'Bergmann glia': '0.2', 'Central nervous system macrophage': '0.6', 'Choroid plexus epithelial cell': '52.1', 'Committed oligodendrocyte precursor': '41.5', 'Ependymal cell': '4.8', 'Oligodendrocyte': '53.1', 'Oligodendrocyte precursor cell': '2.4', 'Endothelial cell': '0.7', 'Pericyte': '0.3', 'Vascular associated smooth muscle cell': '0.0', 'Fibroblast': '17.4', 'Leukocyte': '1.1', 'Basophil': '0.0', 'Eosinophil': '0.0', 'Neutrophil': '0.0', 'Classical monocyte': '0.0', 'Non-classical monocyte': '0.0', 'Intermediate monocyte': '0.0', 'T-reg': '2.3', 'GdT-cell': '0.0', 'MAIT T-cell': '0.0', 'Memory CD4 T-cell': '0.0', 'Naive CD4 T-cell': '0.1', 'Memory CD8 T-cell': '0.2', 'Naive CD8 T-cell': '0.3', 'Memory B-cell': '0.0', 'Naive B-cell': '0.1', 'Plasmacytoid DC': '46.6', 'Myeloid DC': '8.5', 'NK-cell': '0.1', 'Total PBMC': '0.7', 'Vd2 gdTCR': '0.0', 'Memory CD4 T-cell Th1\\/Th17': '0.1', 'Memory CD4 T-cell Th17': '0.2', 'Memory CD4 T-cell Th2': '2.9', 'Non-Vd2 gdTCR': '0.1', 'Memory CD4 T-cell Th1': '0.3', 'Memory CD4 T-cell TFH': '0.5', 'Terminal effector memory CD4 T-cell': '0.0', 'Central memory CD8 T-cell': '4.8', 'Effector memory CD8 T-cell': '0.0', 'Terminal effector memory CD8 T-cell': '0.6', 'Non-switched memory B-cell': '0.0', 'Plasmablast': '3.3', 'Switched memory B-cell': '0.0', 'Exhausted memory B-cell': '0.7', 'Progenitor cell': '2.3', 'Memory T-reg': '1.3', 'Naive CD4 T-cell activated': '0.3', 'Naive CD8 T-cell activated': '0.6', 'Naive T-reg': '0.1'} | 1O6S, 2O72, 2OMT, 2OMU, 2OMV, 2OMX, 2OMY, 2OMZ, 3FF7, 3FF8, 3L6X, 3L6Y, 4ZT1, 4ZTE, 6CXY, 6OLE, 6OLF, 6OLG, 6VEL, 7STZ, 8H62 | {'Adipose Tissue': 1.2125261088039867, 'Adrenal Gland': 0.1914223992248062, 'Bladder': 39.2033519047619, 'Blood': 1.340954264800861, 'Blood Vessel': 0.3121561692883895, 'Brain': 0.8550442199091597, 'Breast': 38.54918344226579, 'Cervix Uteri': 23.539115789473684, 'Colon': 43.41292142490372, 'Esophagus': 53.97513367404844, 'Fallopian Tube': 14.900277777777776, 'Heart': 0.119140469221835, 'Kidney': 25.040449438202245, 'Liver': 26.60802654867257, 'Lung': 35.447986366782004, 'Muscle': 0.1378936151930261, 'Nerve': 17.518468982229404, 'Ovary': 3.6515122222222223, 'Pancreas': 56.89676829268293, 'Pituitary': 24.68741660777385, 'Prostate': 61.279967346938776, 'Salivary Gland': 92.01685185185184, 'Skin': 79.77571720232172, 'Small Intestine': 71.7519320855615, 'Spleen': 10.061029045643156, 'Stomach': 58.07813805013927, 'Testis': 0.8144204986149585, 'Thyroid': 135.176797856049, 'Uterus': 1.442593943661972, 'Vagina': 86.52345512820513} | FBXO5 | MSRRPCSCALRPPRCSCSASPSAVTAAGRPRPSDSCKEESSTLSVKMKCDFNCNHVHSGLKLVKPDDIGRLVSYTPAYLEGSCKDCIKDYERLSCIGSPIVSPRIVQLETESKRLHNKENQHVQQTLNSTNEIEALETSRLYEDSGYSSFSLQSGLSEHEEGSLLEENFGDSLQSCLLQIQSPDQYPNKNLLPVLHFEKVVCSTLKKNAKRNPKVDREMLKEIIARGNFRLQNIIGRKMGLECVDILSELFRRGLRHVLATILAQLSDMDLINVSKVSTTWKKILEDDKGAFQLYSKAIQRVTENNNKFSPHASTREYVMFRTPLASVQKSAAQTSLKKDAQTKLSNQGDQKGSTYSRHNEFSEVAKTLKKNESLKACIRCNSPAKYDCYLQRATCKREGCGFDYCTKCLCNYHTTKDCSDGKLLKASCKIGPLPGTKKSKKNLRRL | Homo sapiens | Nucleus, Cytoplasm, Cytoplasm, cytoskeleton, spindle | Group enriched (bone marrow, lymphoid tissue) | {'Ciliated cells': '1.9', 'Basal respiratory cells': '4.0', 'Club cells': '2.7', 'Ionocytes': '1.1', 'Mucus glandular cells': '5.0', 'Serous glandular cells': '2.1', 'Gastric mucus-secreting cells': '11.2', 'Proximal enterocytes': '1.0', 'Paneth cells': '0.6', 'Distal enterocytes': '1.4', 'Intestinal goblet cells': '4.4', 'Exocrine glandular cells': '-0.567', 'Basal prostatic cells': '4.4', 'Prostatic glandular cells': '6.0', 'Breast glandular cells': '0.446', 'Breast myoepithelial cells': '0.370', 'Glandular and luminal cells': '3.7', 'Secretory cells': '5.8', 'Basal keratinocytes': '10.4', 'Suprabasal keratinocytes': '5.2', 'Basal squamous epithelial cells': '6.6', 'Squamous epithelial cells': '9.2', 'Alveolar cells type 1': '-0.006', 'Alveolar cells type 2': '-0.175', 'Salivary duct cells': '6.9', 'Ductal cells': '0.643', 'Hepatocytes': '0.330', 'Cholangiocytes': '1.9', 'Proximal tubular cells': '0.165', 'Distal tubular cells': '0.0', 'Collecting duct cells': '1.9', 'Mesothelial cells': '0.352', 'Sertoli cells': '0.400', 'Granulosa cells': '10.8', 'Enteroendocrine cells': '2.1', 'Pancreatic endocrine cells': '17.0', 'Leydig cells': '0.489', 'Excitatory neurons': '1.0', 'Inhibitory neurons': '0.9', 'Cone photoreceptor cells': '3.4', 'Rod photoreceptor cells': '3.0', 'Bipolar cells': '2.6', 'Horizontal cells': '1.9', 'Astrocytes': '1.2', 'Oligodendrocyte precursor cells': '1.4', 'Oligodendrocytes': '1.9', 'Microglial cells': '1.8', 'Muller glia cells': '4.4', 'Schwann cells': '0.153', 'Spermatogonia': '0.641', 'Spermatocytes': '0.629', 'Early spermatids': '-0.164', 'Late spermatids': '-0.476', 'Oocytes': '26.5', 'Cytotrophoblasts': '16.5', 'Syncytiotrophoblasts': '5.3', 'Extravillous trophoblasts': '31.2', 'Endothelial cells': '6.2', 'Lymphatic endothelial cells': '6.2', 'Cardiomyocytes': '0.309', 'Skeletal myocytes': '-0.172', 'Smooth muscle cells': '6.6', 'Adipocytes': '6.0', 'Melanocytes': '0.213', 'Fibroblasts': '8.4', 'Peritubular cells': '0.325', 'Endometrial stromal cells': '10.1', 'Ovarian stromal cells': '5.3', 'Undifferentiated cells': '12.7', 'T-cells': '8.3', 'B-cells': '7.8', 'Plasma cells': '24.8', 'Nk-cells': '8.9', 'Granulocytes': '3.3', 'Monocytes': '8.9', 'Macrophages': '6.3', 'Hofbauer cells': '6.2', 'Kupffer cells': '2.1', 'Dendritic cells': '20.8', 'Langerhans cells': '0.227', 'Erythroid cells': '-0.031', 'Adipocytes (Subcutaneous)': '-0.111', 'Adipocytes (Visceral)': '-0.248', 'Breast glandular cells (progenitors)': '0.433', 'Adipocytes (Breast)': '-0.346', 'Colon enterocytes': '0.106', 'Colon enteroendocrine cells': '0.164', 'Enteric glia cells': '-0.141', 'Mitotic cells (Colon)': '0.145', 'Mitotic cells (Heart)': '0.476', 'Podocytes': '-0.092', 'Ascending Loop of Henle cells': '0.388', 'Intercalated cells': '-0.067', 'Cholangiocyte': '0.233', 'NK-cells (Liver)': '-0.103', 'Respiratory ciliated cells': '-0.048', 'Mitotic cells (Lung)': '0.204', 'NK-cells (Lung)': '0.145', 'B-cells (Lung)': '0.013', 'Alpha cells': '0.341', 'Beta cells': '0.231', 'Prostate glandular cells': '-0.098', 'Prostate basal glandular cells': '0.340', 'Urothelial cells': '0.323', 'Keratinocyte (other)': '0.237', 'Keratinocyte (granular)': '-0.213', 'Hair cortex cells': '0.006', 'Inner root sheath cells': '0.109', 'Outer root sheath cells': '0.246', 'Sebaceous gland cells': '0.052', 'Eccrine sweat gland cells': '0.067', 'Adipocytes (Skin)': '-0.163', 'Mitotic cells (Skin)': '0.566', 'Parietal cells': '-0.529', 'Chief cells': '-0.433', 'Gastric mucous cells': '-0.133', 'Gastric enteroendocrine cells': '-0.286', 'Mitotic cells (Stomach)': '0.396', 'Parafollicular cells': '0.040', 'Thyroid glandular cells': '0.243', 'Mitotic cells (Thyroid)': '0.048', 'Adrenal cortex cells': '0.354', 'Adrenal medulla cells': '0.029', 'Mitotic cells (Adrenal gland)': '0.484', 'Minor salivary glandular cells': '0.388', 'Minor salivary gland ductal cells': '-0.028', 'Minor salivary gland basal cells': '0.429', 'Mitotic cells (Minor salivary gland)': '0.573', 'Adipocytes (Minor salivary gland)': '0.163', 'Somatotropes': '0.180', 'Lactotropes': '0.144', 'Gonadotropes': '0.021', 'Corticotropes': '-0.155', 'Thyrotropes': '0.090', 'Undifferentiated cells (Pituitary gland)': '0.224', 'Mitotic cells (Spleen)': '0.611', 'Platelets': '0.046', 'Erythrocytes': '0.101', 'Hematopoietic stem cells': '0.046', 'B-cells (Spleen)': '0.151', 'NK-cells (Spleen)': '0.005', 'Amygdala excitatory': '1.5', 'Cerebellar inhibitory': '1.1', 'Cge interneuron': '1.4', 'Deep-layer corticothalamic and 6b': '1.3', 'Deep-layer intratelencephalic': '1.3', 'Deep-layer near-projecting': '1.5', 'Eccentric medium spiny neuron': '2.7', 'Hippocampal ca1-3': '1.8', 'Hippocampal ca4': '1.2', 'Hippocampal dentate gyrus': '1.1', 'Lamp5-lhx6 and chandelier': '1.7', 'Lower rhombic lip': '3.2', 'Mammillary body': '1.7', 'Medium spiny neuron': '2.0', 'Mge interneuron': '1.1', 'Midbrain-derived inhibitory': '2.1', 'Miscellaneous': '2.3', 'Splatter': '1.7', 'Thalamic excitatory': '1.9', 'Upper rhombic lip': '4.2', 'Upper-layer intratelencephalic': '1.0', 'Astrocyte': '1.3', 'Bergmann glia': '2.4', 'Central nervous system macrophage': '4.4', 'Choroid plexus epithelial cell': '5.3', 'Committed oligodendrocyte precursor': '2.3', 'Ependymal cell': '0.7', 'Oligodendrocyte': '2.5', 'Oligodendrocyte precursor cell': '2.6', 'Endothelial cell': '3.9', 'Pericyte': '3.5', 'Vascular associated smooth 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91.55, 92.21, 93.05, 91.33, 89.08, 90.13, 89.88, 91.44, 92.18, 93.0, 92.05, 92.66, 88.73, 86.97, 85.0, 86.0, 87.7, 91.16, 93.09, 93.6, 93.65, 88.86, 89.18, 87.53, 87.73, 91.27, 89.88, 92.85, 93.67, 93.47, 92.1, 89.65, 88.15, 88.27, 89.22, 86.86, 90.2, 90.86, 89.08, 83.37, 78.19, 78.08, 76.43, 80.67, 71.99, 58.34, 55.77, 48.84, 47.19, 49.81, 40.28, 44.55, 42.06, 40.21, 44.09, 48.92, 58.9, 57.77, 62.93, 55.64, 63.58, 69.35, 69.69, 67.79, 66.27, 67.76, 67.89, 60.38, 61.07, 62.67, 61.57, 49.49] | [1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 0.97, 1.0, 0.92, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 0.98, 0.85, 0.97, 0.84, 0.97, 0.97, 1.0, 0.98, 0.99, 0.86, 0.99, 0.8, 0.86, 0.81, 0.85, 0.82, 0.83, 0.74, 0.9, 0.8, 0.73, 0.7, 0.63, 0.84, 0.75, 0.83, 0.67, 0.75, 0.82, 0.73, 0.78, 0.87, 0.94, 0.91, 0.95, 0.84, 0.88, 0.94, 0.87, 0.99, 1.0, 0.92, 1.0, 1.0, 0.99, 1.0, 1.0, 0.98, 0.98, 0.81, 0.96, 0.88, 0.83, 0.82, 0.61, 0.79, 0.86, 0.87, 0.85, 1.0, 0.92, 0.96, 0.92, 0.96, 0.98, 0.98, 1.0, 0.99, 1.0, 1.0, 1.0, 1.0, 1.0, 0.93, 1.0, 0.92, 0.97, 0.96, 0.88, 0.78, 0.94, 0.81, 0.99, 0.76, 0.98, 0.75, 0.97, 0.9, 0.9, 0.66, 0.8, 0.85, 0.56, 0.6, 0.67, 0.62, 0.68, 0.64, 0.79, 0.82, 0.76, 0.86, 0.92, 0.85, 1.0, 0.87, 1.0, 0.94, 0.86, 0.9, 0.9, 0.84, 0.89, 0.96, 1.0, 1.0, 0.94, 0.74, 0.84, 0.77, 0.85, 0.97, 0.98, 0.92, 0.99, 1.0, 0.99, 0.99, 1.0, 0.99, 1.0, 1.0, 1.0, 1.0, 0.97, 1.0, 0.98, 1.0, 0.99, 0.82, 0.91, 0.84, 0.69, 0.97, 0.79, 0.89, 0.82, 0.7, 0.73, 0.83, 0.84, 0.7, 0.76, 0.76, 0.98, 0.96, 0.89, 0.83, 0.28, 0.82, 0.36, 0.83, 0.91, 0.31, 0.58, 0.39, 0.45, 0.43, 0.18, 0.24, 0.54, 0.57, 0.31, 0.17, 0.51, 0.45, 0.12, 0.37, 0.82, 0.86, 0.09, 0.69, 0.99, 0.61, 0.62, 0.7, 0.75, 0.43, 0.16, 0.7, 0.64, 0.35, 0.17, 0.57, 0.45, 0.2, 0.49, 0.77, 0.76, 0.28, 0.66, 0.07, 0.54, 0.25, 0.62, 0.76, 0.29, 0.88, 0.4, 0.6, 0.4, 0.8, 0.98, 0.52, 0.98, 0.91, 0.42, 0.38, 0.63, 0.09, 0.12, 0.17, 0.17, 0.34, 0.61, 0.58, 0.53, 0.26, 0.59, 0.6, 0.39, 0.05, 0.25, 0.6, 0.36, 0.0, 0.6, 0.84, 0.32, 0.49, 0.38, 0.29, 0.42, 0.01, 0.07, 0.38, 0.08, 0.19, 0.64, 0.6, 0.33, 0.66, 0.41, 0.22, 0.42, 0.56, 0.02, 0.0, 0.47, 0.37, 0.29, 0.77, 0.45, 0.05, 0.39, 0.53, 0.39, 0.14, 0.42, 0.53, 0.02, 0.39, 0.57, 0.46, 0.28, 0.48, 0.37, 0.51, 0.49, 0.79, 0.67, 0.56, 0.69, 0.96, 0.95, 0.83, 0.68, 0.9, 0.98, 0.84, 0.99, 0.54, 0.83, 0.49, 0.77, 0.74, 0.93, 0.76, 0.66, 0.75, 0.67, 0.81, 0.89, 0.67, 0.8, 0.81, 0.88, 0.75, 0.85, 0.84, 0.96, 0.96, 0.97, 0.98, 1.0, 0.98, 1.0, 1.0, 1.0, 1.0, 0.98, 0.97, 0.97, 0.95, 0.9, 0.88, 0.72, 0.82, 0.69, 0.44, 0.4, 0.73, 0.47, 0.15, 0.22, 0.4, 0.56, 0.27, 0.44, 0.64, 0.75, 0.29, 0.73, 0.97, 0.85, 0.32, 0.37, 0.26, 0.31, 0.49, 0.0, 0.42, 0.7, 0.3, 0.51, 0.0, 0.03, 0.0, 0.36, 0.18, 0.4, 0.48, 0.94, 0.51, 0.27, 0.35, 0.0, 0.34, 0.07, 0.6, 0.36, 0.92, 0.92, 0.28, 0.48, 0.1, 0.26, 0.03, 0.02, 0.15, 0.47, 0.1, 0.33, 0.45, 0.64, 0.3, 0.3, 0.86, 1.0, 0.78, 0.92, 0.24, 0.61, 0.56, 0.93, 0.83, 0.78, 0.57, 0.92, 0.67, 0.91, 0.81, 0.92, 0.89, 0.71, 0.55, 0.71, 0.93, 0.55, 0.35, 0.87, 0.77, 0.27, 0.62, 0.8, 0.79, 0.65, 0.88, 0.94, 0.87] | null | Component of an E-cadherin/ catenin adhesion complex composed of at least E-cadherin/CDH1, beta-catenin/CTNNB1 or gamma-catenin/JUP, and potentially alpha-catenin/CTNNA1. Forms a ternary complex composed of ADAM10, CADH1 and EPHA4, | null | null | KLRG1, SPEF1, DLGAP5, AJAP1, RAPGEF2, RAB8B, PIP5K1C, PKP2, TRPV4, CTNNB1, CAV1, DDR1, TBC1D2, CTNNA1, JUP, CTNND1, PSEN1, LIMA1, CDH1, JUP, ADAM10, CADH1 , EPHA4, | null | null | null | null | Homodimer | null | 79.91949 | 0.474025 | 59.797673 | 0.69217 | 1,776 |
P12830 | Q9ULW0 | null | degron_data | CDH1 | MGPWSRSLSALLLLLQVSSWLCQEPEPCHPGFDAESYTFTVPRRHLERGRVLGRVNFEDCTGRQRTAYFSLDTRFKVGTDGVITVKRPLRFHNPQIHFLVYAWDSTYRKFSTKVTLNTVGHHHRPPPHQASVSGIQAELLTFPNSSPGLRRQKRDWVIPPISCPENEKGPFPKNLVQIKSNKDKEGKVFYSITGQGADTPPVGVFIIERETGWLKVTEPLDRERIATYTLFSHAVSSNGNAVEDPMEILITVTDQNDNKPEFTQEVFKGSVMEGALPGTSVMEVTATDADDDVNTYNAAIAYTILSQDPELPDKNMFTINRNTGVISVVTTGLDRESFPTYTLVVQAADLQGEGLSTTATAVITVTDTNDNPPIFNPTTYKGQVPENEANVVITTLKVTDADAPNTPAWEAVYTILNDDGGQFVVTTNPVNNDGILKTAKGLDFEAKQQYILHVAVTNVVPFEVSLTTSTATVTVDVLDVNEAPIFVPPEKRVEVSEDFGVGQEITSYTAQEPDTFMEQKITYRIWRDTANWLEINPDTGAISTRAELDREDFEHVKNSTYTALIIATDNGSPVATGTGTLLLILSDVNDNAPIPEPRTIFFCERNPKPQVINIIDADLPPNTSPFTAELTHGASANWTIQYNDPTQESIILKPKMALEVGDYKINLKLMDNQNKDQVTTLEVSVCDCEGAAGVCRKAQPVEAGLQIPAILGILGGILALLILILLLLLFLRRRAVVKEPLLPPEDDTRDNVYYYDEEGGGEEDQDFDLSQLHRGLDARPEVTRNDVAPTLMSVPRYLPRPANPDEIGNFIDENLKAADTDPTAPPYDSLLVFDYEGSGSEAASLSSLNSSESDKDQDYDYLNEWGNRFKKLADMYGGGEDD | Homo sapiens | Cell junction, adherens junction, Cell membrane, Endosome, Golgi apparatus, trans-Golgi network, Cytoplasm, Cell junction, desmosome | Tissue enhanced (parathyroid) | {'Ciliated cells': '119.1', 'Basal respiratory cells': '71.1', 'Club cells': '97.3', 'Ionocytes': '81.0', 'Mucus glandular cells': '155.0', 'Serous glandular cells': '67.8', 'Gastric mucus-secreting cells': '133.2', 'Proximal enterocytes': '140.9', 'Paneth cells': '125.1', 'Distal enterocytes': '307.5', 'Intestinal goblet cells': '173.5', 'Exocrine glandular cells': '-0.605', 'Basal prostatic cells': '68.3', 'Prostatic glandular cells': '186.7', 'Breast glandular cells': '0.773', 'Breast myoepithelial cells': '0.700', 'Glandular and luminal cells': '313.0', 'Secretory cells': '82.3', 'Basal keratinocytes': '102.5', 'Suprabasal keratinocytes': '162.6', 'Basal squamous epithelial cells': '51.0', 'Squamous epithelial cells': '106.9', 'Alveolar cells type 1': '0.437', 'Alveolar cells type 2': '0.706', 'Salivary duct cells': '95.9', 'Ductal cells': '0.541', 'Hepatocytes': '0.600', 'Cholangiocytes': '129.7', 'Proximal tubular cells': '0.042', 'Distal tubular cells': '0.0', 'Collecting duct cells': '143.9', 'Mesothelial cells': '0.799', 'Sertoli cells': '0.252', 'Granulosa cells': '12.9', 'Enteroendocrine cells': '92.4', 'Pancreatic endocrine cells': '78.1', 'Leydig cells': '0.264', 'Excitatory neurons': '0.7', 'Inhibitory neurons': '1.3', 'Cone photoreceptor cells': '0.0', 'Rod photoreceptor cells': '0.0', 'Bipolar cells': '0.2', 'Horizontal cells': '0.6', 'Astrocytes': '0.6', 'Oligodendrocyte precursor cells': '0.5', 'Oligodendrocytes': '29.9', 'Microglial cells': '0.9', 'Muller glia cells': '0.1', 'Schwann cells': '0.131', 'Spermatogonia': '0.392', 'Spermatocytes': '0.193', 'Early spermatids': '-0.217', 'Late spermatids': '-0.290', 'Oocytes': '16.9', 'Cytotrophoblasts': '119.2', 'Syncytiotrophoblasts': '45.0', 'Extravillous trophoblasts': '24.9', 'Endothelial cells': '6.1', 'Lymphatic endothelial cells': '0.4', 'Cardiomyocytes': '0.135', 'Skeletal myocytes': '0.107', 'Smooth muscle cells': '5.8', 'Adipocytes': '2.1', 'Melanocytes': '0.335', 'Fibroblasts': '6.5', 'Peritubular cells': '0.210', 'Endometrial stromal cells': '27.7', 'Ovarian stromal cells': '0.7', 'Undifferentiated cells': '101.6', 'T-cells': '2.9', 'B-cells': '4.4', 'Plasma cells': '6.1', 'Nk-cells': '0.0', 'Granulocytes': '8.4', 'Monocytes': '0.0', 'Macrophages': '6.0', 'Hofbauer cells': '4.3', 'Kupffer cells': '1.0', 'Dendritic cells': '5.9', 'Langerhans cells': '0.304', 'Erythroid cells': '0.036', 'Adipocytes (Subcutaneous)': '-0.081', 'Adipocytes (Visceral)': '-0.209', 'Breast glandular cells (progenitors)': '0.538', 'Adipocytes (Breast)': '-0.689', 'Colon enterocytes': '0.790', 'Colon enteroendocrine cells': '0.112', 'Enteric glia cells': '-0.048', 'Mitotic cells (Colon)': '0.299', 'Mitotic cells (Heart)': '0.120', 'Podocytes': '-0.118', 'Ascending Loop of Henle cells': '0.475', 'Intercalated cells': '0.212', 'Cholangiocyte': '0.090', 'NK-cells (Liver)': '-0.005', 'Respiratory ciliated cells': '-0.012', 'Mitotic cells (Lung)': '0.071', 'NK-cells (Lung)': '-0.266', 'B-cells (Lung)': '-0.296', 'Alpha cells': '0.270', 'Beta cells': '0.152', 'Prostate glandular cells': '0.764', 'Prostate basal glandular cells': '0.540', 'Urothelial cells': '0.205', 'Keratinocyte (other)': '0.510', 'Keratinocyte (granular)': '0.055', 'Hair cortex cells': '0.080', 'Inner root sheath cells': '0.131', 'Outer root sheath cells': '0.175', 'Sebaceous gland cells': '0.156', 'Eccrine sweat gland cells': '-0.207', 'Adipocytes (Skin)': '-0.244', 'Mitotic cells (Skin)': '0.442', 'Parietal cells': '0.654', 'Chief cells': '0.649', 'Gastric mucous cells': '0.781', 'Gastric enteroendocrine cells': '0.590', 'Mitotic cells (Stomach)': '0.445', 'Parafollicular cells': '0.173', 'Thyroid glandular cells': '0.865', 'Mitotic cells (Thyroid)': '-0.081', 'Adrenal cortex cells': '0.051', 'Adrenal medulla cells': '0.087', 'Mitotic cells (Adrenal gland)': '0.072', 'Minor salivary glandular cells': '0.371', 'Minor salivary gland ductal cells': '-0.142', 'Minor salivary gland basal cells': '0.582', 'Mitotic cells (Minor salivary gland)': '0.567', 'Adipocytes (Minor salivary gland)': '0.050', 'Somatotropes': '0.121', 'Lactotropes': '0.322', 'Gonadotropes': '0.330', 'Corticotropes': '0.180', 'Thyrotropes': '0.496', 'Undifferentiated cells (Pituitary gland)': '-0.108', 'Mitotic cells (Spleen)': '-0.228', 'Platelets': '-0.050', 'Erythrocytes': '-0.158', 'Hematopoietic stem cells': '-0.211', 'B-cells (Spleen)': '0.266', 'NK-cells (Spleen)': '0.309', 'Amygdala excitatory': '1.0', 'Cerebellar inhibitory': '0.9', 'Cge interneuron': '0.7', 'Deep-layer corticothalamic and 6b': '1.5', 'Deep-layer intratelencephalic': '0.7', 'Deep-layer near-projecting': '0.7', 'Eccentric medium spiny neuron': '0.6', 'Hippocampal ca1-3': '1.9', 'Hippocampal ca4': '1.2', 'Hippocampal dentate gyrus': '1.1', 'Lamp5-lhx6 and chandelier': '0.5', 'Lower rhombic lip': '0.8', 'Mammillary body': '0.6', 'Medium spiny neuron': '0.7', 'Mge interneuron': '1.7', 'Midbrain-derived inhibitory': '0.7', 'Miscellaneous': '0.9', 'Splatter': '3.8', 'Thalamic excitatory': '0.5', 'Upper rhombic lip': '0.8', 'Upper-layer intratelencephalic': '0.6', 'Astrocyte': '4.4', 'Bergmann glia': '0.2', 'Central nervous system macrophage': '0.6', 'Choroid plexus epithelial cell': '52.1', 'Committed oligodendrocyte precursor': '41.5', 'Ependymal cell': '4.8', 'Oligodendrocyte': '53.1', 'Oligodendrocyte precursor cell': '2.4', 'Endothelial cell': '0.7', 'Pericyte': '0.3', 'Vascular associated smooth muscle cell': '0.0', 'Fibroblast': '17.4', 'Leukocyte': '1.1', 'Basophil': '0.0', 'Eosinophil': '0.0', 'Neutrophil': '0.0', 'Classical monocyte': '0.0', 'Non-classical monocyte': '0.0', 'Intermediate monocyte': '0.0', 'T-reg': '2.3', 'GdT-cell': '0.0', 'MAIT T-cell': '0.0', 'Memory CD4 T-cell': '0.0', 'Naive CD4 T-cell': '0.1', 'Memory CD8 T-cell': '0.2', 'Naive CD8 T-cell': '0.3', 'Memory B-cell': '0.0', 'Naive B-cell': '0.1', 'Plasmacytoid DC': '46.6', 'Myeloid DC': '8.5', 'NK-cell': '0.1', 'Total PBMC': '0.7', 'Vd2 gdTCR': '0.0', 'Memory CD4 T-cell Th1\\/Th17': '0.1', 'Memory CD4 T-cell Th17': '0.2', 'Memory CD4 T-cell Th2': '2.9', 'Non-Vd2 gdTCR': '0.1', 'Memory CD4 T-cell Th1': '0.3', 'Memory CD4 T-cell TFH': '0.5', 'Terminal effector memory CD4 T-cell': '0.0', 'Central memory CD8 T-cell': '4.8', 'Effector memory CD8 T-cell': '0.0', 'Terminal effector memory CD8 T-cell': '0.6', 'Non-switched memory B-cell': '0.0', 'Plasmablast': '3.3', 'Switched memory B-cell': '0.0', 'Exhausted memory B-cell': '0.7', 'Progenitor cell': '2.3', 'Memory T-reg': '1.3', 'Naive CD4 T-cell activated': '0.3', 'Naive CD8 T-cell activated': '0.6', 'Naive T-reg': '0.1'} | 1O6S, 2O72, 2OMT, 2OMU, 2OMV, 2OMX, 2OMY, 2OMZ, 3FF7, 3FF8, 3L6X, 3L6Y, 4ZT1, 4ZTE, 6CXY, 6OLE, 6OLF, 6OLG, 6VEL, 7STZ, 8H62 | {'Adipose Tissue': 1.2125261088039867, 'Adrenal Gland': 0.1914223992248062, 'Bladder': 39.2033519047619, 'Blood': 1.340954264800861, 'Blood Vessel': 0.3121561692883895, 'Brain': 0.8550442199091597, 'Breast': 38.54918344226579, 'Cervix Uteri': 23.539115789473684, 'Colon': 43.41292142490372, 'Esophagus': 53.97513367404844, 'Fallopian Tube': 14.900277777777776, 'Heart': 0.119140469221835, 'Kidney': 25.040449438202245, 'Liver': 26.60802654867257, 'Lung': 35.447986366782004, 'Muscle': 0.1378936151930261, 'Nerve': 17.518468982229404, 'Ovary': 3.6515122222222223, 'Pancreas': 56.89676829268293, 'Pituitary': 24.68741660777385, 'Prostate': 61.279967346938776, 'Salivary Gland': 92.01685185185184, 'Skin': 79.77571720232172, 'Small Intestine': 71.7519320855615, 'Spleen': 10.061029045643156, 'Stomach': 58.07813805013927, 'Testis': 0.8144204986149585, 'Thyroid': 135.176797856049, 'Uterus': 1.442593943661972, 'Vagina': 86.52345512820513} | TPX2 | MSQVKSSYSYDAPSDFINFSSLDDEGDTQNIDSWFEEKANLENKLLGKNGTGGLFQGKTPLRKANLQQAIVTPLKPVDNTYYKEAEKENLVEQSIPSNACSSLEVEAAISRKTPAQPQRRSLRLSAQKDLEQKEKHHVKMKAKRCATPVIIDEILPSKKMKVSNNKKKPEEEGSAHQDTAEKNASSPEKAKGRHTVPCMPPAKQKFLKSTEEQELEKSMKMQQEVVEMRKKNEEFKKLALAGIGQPVKKSVSQVTKSVDFHFRTDERIKQHPKNQEEYKEVNFTSELRKHPSSPARVTKGCTIVKPFNLSQGKKRTFDETVSTYVPLAQQVEDFHKRTPNRYHLRSKKDDINLLPSKSSVTKICRDPQTPVLQTKHRARAVTCKSTAELEAEELEKLQQYKFKARELDPRILEGGPILPKKPPVKPPTEPIGFDLEIEKRIQERESKKKTEDEHFEFHSRPCPTKILEDVVGVPEKKVLPITVPKSPAFALKNRIRMPTKEDEEEDEPVVIKAQPVPHYGVPFKPQIPEARTVEICPFSFDSRDKERQLQKEKKIKELQKGEVPKFKALPLPHFDTINLPEKKVKNVTQIEPFCLETDRRGALKAQTWKHQLEEELRQQKEAACFKARPNTVISQEPFVPKKEKKSVAEGLSGSLVQEPFQLATEKRAKERQELEKRMAEVEAQKAQQLEEARLQEEEQKKEELARLRRELVHKANPIRKYQGLEIKSSDQPLTVPVSPKFSTRFHC | Homo sapiens | Nucleus, Cytoplasm, cytoskeleton, spindle, Cytoplasm, cytoskeleton, spindle pole | Tissue enhanced (bone marrow, lymphoid tissue, testis) | {'Ciliated cells': '3.9', 'Basal respiratory cells': '4.3', 'Club cells': '3.1', 'Ionocytes': '1.5', 'Mucus glandular cells': '2.3', 'Serous glandular cells': '9.1', 'Gastric mucus-secreting cells': '17.7', 'Proximal enterocytes': '0.6', 'Paneth cells': '0.2', 'Distal enterocytes': '1.5', 'Intestinal goblet cells': '8.4', 'Exocrine glandular cells': '-0.291', 'Basal prostatic cells': '0.0', 'Prostatic glandular cells': '0.1', 'Breast glandular cells': '-0.001', 'Breast myoepithelial cells': '0.077', 'Glandular and luminal cells': '8.2', 'Secretory cells': '1.2', 'Basal keratinocytes': '23.4', 'Suprabasal keratinocytes': '10.1', 'Basal squamous epithelial cells': '9.5', 'Squamous epithelial cells': '29.3', 'Alveolar cells type 1': '-0.273', 'Alveolar cells type 2': '0.108', 'Salivary duct cells': '3.3', 'Ductal cells': '0.459', 'Hepatocytes': '0.399', 'Cholangiocytes': '0.0', 'Proximal tubular cells': '0.210', 'Distal tubular cells': '0.0', 'Collecting duct cells': '0.0', 'Mesothelial cells': '-0.020', 'Sertoli cells': '0.087', 'Granulosa cells': '5.8', 'Enteroendocrine cells': '3.0', 'Pancreatic endocrine cells': '10.2', 'Leydig cells': '-0.006', 'Excitatory neurons': '2.8', 'Inhibitory neurons': '0.8', 'Cone photoreceptor cells': '1.7', 'Rod photoreceptor cells': '0.3', 'Bipolar cells': '0.1', 'Horizontal cells': '1.3', 'Astrocytes': '0.0', 'Oligodendrocyte precursor cells': '0.5', 'Oligodendrocytes': '0.5', 'Microglial cells': '0.9', 'Muller glia cells': '0.5', 'Schwann cells': '0.110', 'Spermatogonia': '0.434', 'Spermatocytes': '0.758', 'Early spermatids': '0.474', 'Late spermatids': '0.036', 'Oocytes': '44.1', 'Cytotrophoblasts': '24.7', 'Syncytiotrophoblasts': '6.0', 'Extravillous trophoblasts': '72.9', 'Endothelial cells': '2.6', 'Lymphatic endothelial cells': '0.3', 'Cardiomyocytes': '0.356', 'Skeletal myocytes': '0.094', 'Smooth muscle cells': '5.7', 'Adipocytes': '0.9', 'Melanocytes': '0.546', 'Fibroblasts': '5.1', 'Peritubular cells': '-0.102', 'Endometrial stromal cells': '5.2', 'Ovarian stromal cells': '0.7', 'Undifferentiated cells': '37.3', 'T-cells': '7.0', 'B-cells': '2.9', 'Plasma cells': '38.0', 'Nk-cells': '4.3', 'Granulocytes': '0.3', 'Monocytes': '0.2', 'Macrophages': '7.8', 'Hofbauer cells': '13.9', 'Kupffer cells': '6.7', 'Dendritic cells': '4.1', 'Langerhans cells': '0.193', 'Erythroid cells': '0.031', 'Adipocytes (Subcutaneous)': '-0.118', 'Adipocytes (Visceral)': '-0.072', 'Breast glandular cells (progenitors)': '0.014', 'Adipocytes (Breast)': '0.035', 'Colon enterocytes': '0.357', 'Colon enteroendocrine cells': '-0.045', 'Enteric glia cells': '-0.084', 'Mitotic cells (Colon)': '0.760', 'Mitotic cells (Heart)': '0.815', 'Podocytes': '-0.198', 'Ascending Loop of Henle cells': '0.291', 'Intercalated cells': '-0.151', 'Cholangiocyte': '0.164', 'NK-cells (Liver)': '-0.119', 'Respiratory ciliated cells': '-0.005', 'Mitotic cells (Lung)': '0.940', 'NK-cells (Lung)': '-0.107', 'B-cells (Lung)': '0.042', 'Alpha cells': '0.157', 'Beta cells': '0.041', 'Prostate glandular cells': '-0.172', 'Prostate basal glandular cells': '0.126', 'Urothelial cells': '0.208', 'Keratinocyte (other)': '0.337', 'Keratinocyte (granular)': '-0.050', 'Hair cortex cells': '0.086', 'Inner root sheath cells': '0.224', 'Outer root sheath cells': '0.187', 'Sebaceous gland cells': '0.053', 'Eccrine sweat gland cells': '-0.090', 'Adipocytes (Skin)': '-0.159', 'Mitotic cells (Skin)': '0.880', 'Parietal cells': '0.162', 'Chief cells': '0.119', 'Gastric mucous cells': '0.574', 'Gastric enteroendocrine cells': '0.216', 'Mitotic cells (Stomach)': '0.935', 'Parafollicular cells': '-0.056', 'Thyroid glandular cells': '-0.024', 'Mitotic cells (Thyroid)': '0.725', 'Adrenal cortex cells': '0.462', 'Adrenal medulla cells': '0.057', 'Mitotic cells (Adrenal gland)': '0.873', 'Minor salivary glandular cells': '0.112', 'Minor salivary gland ductal cells': '-0.332', 'Minor salivary gland basal cells': '0.681', 'Mitotic cells (Minor salivary gland)': '0.971', 'Adipocytes (Minor salivary gland)': '0.171', 'Somatotropes': '-0.354', 'Lactotropes': '-0.286', 'Gonadotropes': '-0.045', 'Corticotropes': '-0.112', 'Thyrotropes': '-0.080', 'Undifferentiated cells (Pituitary gland)': '0.459', 'Mitotic cells (Spleen)': '0.957', 'Platelets': '0.186', 'Erythrocytes': '0.337', 'Hematopoietic stem cells': '0.420', 'B-cells (Spleen)': '-0.127', 'NK-cells (Spleen)': '-0.220', 'Amygdala excitatory': '3.2', 'Cerebellar inhibitory': '0.9', 'Cge interneuron': '1.5', 'Deep-layer corticothalamic and 6b': '5.1', 'Deep-layer intratelencephalic': '5.2', 'Deep-layer near-projecting': '3.3', 'Eccentric medium spiny neuron': '2.8', 'Hippocampal ca1-3': '2.7', 'Hippocampal ca4': '3.3', 'Hippocampal dentate gyrus': '1.8', 'Lamp5-lhx6 and chandelier': '0.6', 'Lower rhombic lip': '4.5', 'Mammillary body': '0.7', 'Medium spiny neuron': '3.6', 'Mge interneuron': '1.2', 'Midbrain-derived inhibitory': '0.7', 'Miscellaneous': '3.3', 'Splatter': '2.1', 'Thalamic excitatory': '2.7', 'Upper rhombic lip': '2.4', 'Upper-layer intratelencephalic': '3.8', 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0.33, 0.61, 0.59, 0.54, 0.57, 0.7, 0.66, 0.46, 0.28, 0.59, 0.5, 0.62, 0.66, 0.61, 0.6, 0.53, 0.87, 0.79, 0.91, 0.55, 0.57, 0.58, 0.45, 0.93, 0.71, 0.96, 0.88, 0.86, 0.82, 0.88, 0.86, 0.8, 0.82, 0.85, 0.87, 0.87, 0.93, 0.9, 0.82, 0.93, 0.89, 0.9, 0.64, 0.9, 0.85, 0.59, 0.76, 0.92, 0.92, 0.81, 0.96] | null | Component of an E-cadherin/ catenin adhesion complex composed of at least E-cadherin/CDH1, beta-catenin/CTNNB1 or gamma-catenin/JUP, and potentially alpha-catenin/CTNNA1. Forms a ternary complex composed of ADAM10, CADH1 and EPHA4, | null | null | KLRG1, SPEF1, DLGAP5, AJAP1, RAPGEF2, RAB8B, PIP5K1C, PKP2, TRPV4, CTNNB1, CAV1, DDR1, TBC1D2, CTNNA1, JUP, CTNND1, PSEN1, LIMA1, CDH1, JUP, ADAM10, CADH1 , EPHA4, | null | null | null | null | Homodimer | null | 79.91949 | 0.474025 | 63.652329 | 0.787992 | 904 |
P12830 | Q9UM11 | null | degron_data | CDH1 | MGPWSRSLSALLLLLQVSSWLCQEPEPCHPGFDAESYTFTVPRRHLERGRVLGRVNFEDCTGRQRTAYFSLDTRFKVGTDGVITVKRPLRFHNPQIHFLVYAWDSTYRKFSTKVTLNTVGHHHRPPPHQASVSGIQAELLTFPNSSPGLRRQKRDWVIPPISCPENEKGPFPKNLVQIKSNKDKEGKVFYSITGQGADTPPVGVFIIERETGWLKVTEPLDRERIATYTLFSHAVSSNGNAVEDPMEILITVTDQNDNKPEFTQEVFKGSVMEGALPGTSVMEVTATDADDDVNTYNAAIAYTILSQDPELPDKNMFTINRNTGVISVVTTGLDRESFPTYTLVVQAADLQGEGLSTTATAVITVTDTNDNPPIFNPTTYKGQVPENEANVVITTLKVTDADAPNTPAWEAVYTILNDDGGQFVVTTNPVNNDGILKTAKGLDFEAKQQYILHVAVTNVVPFEVSLTTSTATVTVDVLDVNEAPIFVPPEKRVEVSEDFGVGQEITSYTAQEPDTFMEQKITYRIWRDTANWLEINPDTGAISTRAELDREDFEHVKNSTYTALIIATDNGSPVATGTGTLLLILSDVNDNAPIPEPRTIFFCERNPKPQVINIIDADLPPNTSPFTAELTHGASANWTIQYNDPTQESIILKPKMALEVGDYKINLKLMDNQNKDQVTTLEVSVCDCEGAAGVCRKAQPVEAGLQIPAILGILGGILALLILILLLLLFLRRRAVVKEPLLPPEDDTRDNVYYYDEEGGGEEDQDFDLSQLHRGLDARPEVTRNDVAPTLMSVPRYLPRPANPDEIGNFIDENLKAADTDPTAPPYDSLLVFDYEGSGSEAASLSSLNSSESDKDQDYDYLNEWGNRFKKLADMYGGGEDD | Homo sapiens | Cell junction, adherens junction, Cell membrane, Endosome, Golgi apparatus, trans-Golgi network, Cytoplasm, Cell junction, desmosome | Tissue enhanced (parathyroid) | {'Ciliated cells': '119.1', 'Basal respiratory cells': '71.1', 'Club cells': '97.3', 'Ionocytes': '81.0', 'Mucus glandular cells': '155.0', 'Serous glandular cells': '67.8', 'Gastric mucus-secreting cells': '133.2', 'Proximal enterocytes': '140.9', 'Paneth cells': '125.1', 'Distal enterocytes': '307.5', 'Intestinal goblet cells': '173.5', 'Exocrine glandular cells': '-0.605', 'Basal prostatic cells': '68.3', 'Prostatic glandular cells': '186.7', 'Breast glandular cells': '0.773', 'Breast myoepithelial cells': '0.700', 'Glandular and luminal cells': '313.0', 'Secretory cells': '82.3', 'Basal keratinocytes': '102.5', 'Suprabasal keratinocytes': '162.6', 'Basal squamous epithelial cells': '51.0', 'Squamous epithelial cells': '106.9', 'Alveolar cells type 1': '0.437', 'Alveolar cells type 2': '0.706', 'Salivary duct cells': '95.9', 'Ductal cells': '0.541', 'Hepatocytes': '0.600', 'Cholangiocytes': '129.7', 'Proximal tubular cells': '0.042', 'Distal tubular cells': '0.0', 'Collecting duct cells': '143.9', 'Mesothelial cells': '0.799', 'Sertoli cells': '0.252', 'Granulosa cells': '12.9', 'Enteroendocrine cells': '92.4', 'Pancreatic endocrine cells': '78.1', 'Leydig cells': '0.264', 'Excitatory neurons': '0.7', 'Inhibitory neurons': '1.3', 'Cone photoreceptor cells': '0.0', 'Rod photoreceptor cells': '0.0', 'Bipolar cells': '0.2', 'Horizontal cells': '0.6', 'Astrocytes': '0.6', 'Oligodendrocyte precursor cells': '0.5', 'Oligodendrocytes': '29.9', 'Microglial cells': '0.9', 'Muller glia cells': '0.1', 'Schwann cells': '0.131', 'Spermatogonia': '0.392', 'Spermatocytes': '0.193', 'Early spermatids': '-0.217', 'Late spermatids': '-0.290', 'Oocytes': '16.9', 'Cytotrophoblasts': '119.2', 'Syncytiotrophoblasts': '45.0', 'Extravillous trophoblasts': '24.9', 'Endothelial cells': '6.1', 'Lymphatic endothelial cells': '0.4', 'Cardiomyocytes': '0.135', 'Skeletal myocytes': '0.107', 'Smooth muscle cells': '5.8', 'Adipocytes': '2.1', 'Melanocytes': '0.335', 'Fibroblasts': '6.5', 'Peritubular cells': '0.210', 'Endometrial stromal cells': '27.7', 'Ovarian stromal cells': '0.7', 'Undifferentiated cells': '101.6', 'T-cells': '2.9', 'B-cells': '4.4', 'Plasma cells': '6.1', 'Nk-cells': '0.0', 'Granulocytes': '8.4', 'Monocytes': '0.0', 'Macrophages': '6.0', 'Hofbauer cells': '4.3', 'Kupffer cells': '1.0', 'Dendritic cells': '5.9', 'Langerhans cells': '0.304', 'Erythroid cells': '0.036', 'Adipocytes (Subcutaneous)': '-0.081', 'Adipocytes (Visceral)': '-0.209', 'Breast glandular cells (progenitors)': '0.538', 'Adipocytes (Breast)': '-0.689', 'Colon enterocytes': '0.790', 'Colon enteroendocrine cells': '0.112', 'Enteric glia cells': '-0.048', 'Mitotic cells (Colon)': '0.299', 'Mitotic cells (Heart)': '0.120', 'Podocytes': '-0.118', 'Ascending Loop of Henle cells': '0.475', 'Intercalated cells': '0.212', 'Cholangiocyte': '0.090', 'NK-cells (Liver)': '-0.005', 'Respiratory ciliated cells': '-0.012', 'Mitotic cells (Lung)': '0.071', 'NK-cells (Lung)': '-0.266', 'B-cells (Lung)': '-0.296', 'Alpha cells': '0.270', 'Beta cells': '0.152', 'Prostate glandular cells': '0.764', 'Prostate basal glandular cells': '0.540', 'Urothelial cells': '0.205', 'Keratinocyte (other)': '0.510', 'Keratinocyte (granular)': '0.055', 'Hair cortex cells': '0.080', 'Inner root sheath cells': '0.131', 'Outer root sheath cells': '0.175', 'Sebaceous gland cells': '0.156', 'Eccrine sweat gland cells': '-0.207', 'Adipocytes (Skin)': '-0.244', 'Mitotic cells (Skin)': '0.442', 'Parietal cells': '0.654', 'Chief cells': '0.649', 'Gastric mucous cells': '0.781', 'Gastric enteroendocrine cells': '0.590', 'Mitotic cells (Stomach)': '0.445', 'Parafollicular cells': '0.173', 'Thyroid glandular cells': '0.865', 'Mitotic cells (Thyroid)': '-0.081', 'Adrenal cortex cells': '0.051', 'Adrenal medulla cells': '0.087', 'Mitotic cells (Adrenal gland)': '0.072', 'Minor salivary glandular cells': '0.371', 'Minor salivary gland ductal cells': '-0.142', 'Minor salivary gland basal cells': '0.582', 'Mitotic cells (Minor salivary gland)': '0.567', 'Adipocytes (Minor salivary gland)': '0.050', 'Somatotropes': '0.121', 'Lactotropes': '0.322', 'Gonadotropes': '0.330', 'Corticotropes': '0.180', 'Thyrotropes': '0.496', 'Undifferentiated cells (Pituitary gland)': '-0.108', 'Mitotic cells (Spleen)': '-0.228', 'Platelets': '-0.050', 'Erythrocytes': '-0.158', 'Hematopoietic stem cells': '-0.211', 'B-cells (Spleen)': '0.266', 'NK-cells (Spleen)': '0.309', 'Amygdala excitatory': '1.0', 'Cerebellar inhibitory': '0.9', 'Cge interneuron': '0.7', 'Deep-layer corticothalamic and 6b': '1.5', 'Deep-layer intratelencephalic': '0.7', 'Deep-layer near-projecting': '0.7', 'Eccentric medium spiny neuron': '0.6', 'Hippocampal ca1-3': '1.9', 'Hippocampal ca4': '1.2', 'Hippocampal dentate gyrus': '1.1', 'Lamp5-lhx6 and chandelier': '0.5', 'Lower rhombic lip': '0.8', 'Mammillary body': '0.6', 'Medium spiny neuron': '0.7', 'Mge interneuron': '1.7', 'Midbrain-derived inhibitory': '0.7', 'Miscellaneous': '0.9', 'Splatter': '3.8', 'Thalamic excitatory': '0.5', 'Upper rhombic lip': '0.8', 'Upper-layer intratelencephalic': '0.6', 'Astrocyte': '4.4', 'Bergmann glia': '0.2', 'Central nervous system macrophage': '0.6', 'Choroid plexus epithelial cell': '52.1', 'Committed oligodendrocyte precursor': '41.5', 'Ependymal cell': '4.8', 'Oligodendrocyte': '53.1', 'Oligodendrocyte precursor cell': '2.4', 'Endothelial cell': '0.7', 'Pericyte': '0.3', 'Vascular associated smooth muscle cell': '0.0', 'Fibroblast': '17.4', 'Leukocyte': '1.1', 'Basophil': '0.0', 'Eosinophil': '0.0', 'Neutrophil': '0.0', 'Classical monocyte': '0.0', 'Non-classical monocyte': '0.0', 'Intermediate monocyte': '0.0', 'T-reg': '2.3', 'GdT-cell': '0.0', 'MAIT T-cell': '0.0', 'Memory CD4 T-cell': '0.0', 'Naive CD4 T-cell': '0.1', 'Memory CD8 T-cell': '0.2', 'Naive CD8 T-cell': '0.3', 'Memory B-cell': '0.0', 'Naive B-cell': '0.1', 'Plasmacytoid DC': '46.6', 'Myeloid DC': '8.5', 'NK-cell': '0.1', 'Total PBMC': '0.7', 'Vd2 gdTCR': '0.0', 'Memory CD4 T-cell Th1\\/Th17': '0.1', 'Memory CD4 T-cell Th17': '0.2', 'Memory CD4 T-cell Th2': '2.9', 'Non-Vd2 gdTCR': '0.1', 'Memory CD4 T-cell Th1': '0.3', 'Memory CD4 T-cell TFH': '0.5', 'Terminal effector memory CD4 T-cell': '0.0', 'Central memory CD8 T-cell': '4.8', 'Effector memory CD8 T-cell': '0.0', 'Terminal effector memory CD8 T-cell': '0.6', 'Non-switched memory B-cell': '0.0', 'Plasmablast': '3.3', 'Switched memory B-cell': '0.0', 'Exhausted memory B-cell': '0.7', 'Progenitor cell': '2.3', 'Memory T-reg': '1.3', 'Naive CD4 T-cell activated': '0.3', 'Naive CD8 T-cell activated': '0.6', 'Naive T-reg': '0.1'} | 1O6S, 2O72, 2OMT, 2OMU, 2OMV, 2OMX, 2OMY, 2OMZ, 3FF7, 3FF8, 3L6X, 3L6Y, 4ZT1, 4ZTE, 6CXY, 6OLE, 6OLF, 6OLG, 6VEL, 7STZ, 8H62 | {'Adipose Tissue': 1.2125261088039867, 'Adrenal Gland': 0.1914223992248062, 'Bladder': 39.2033519047619, 'Blood': 1.340954264800861, 'Blood Vessel': 0.3121561692883895, 'Brain': 0.8550442199091597, 'Breast': 38.54918344226579, 'Cervix Uteri': 23.539115789473684, 'Colon': 43.41292142490372, 'Esophagus': 53.97513367404844, 'Fallopian Tube': 14.900277777777776, 'Heart': 0.119140469221835, 'Kidney': 25.040449438202245, 'Liver': 26.60802654867257, 'Lung': 35.447986366782004, 'Muscle': 0.1378936151930261, 'Nerve': 17.518468982229404, 'Ovary': 3.6515122222222223, 'Pancreas': 56.89676829268293, 'Pituitary': 24.68741660777385, 'Prostate': 61.279967346938776, 'Salivary Gland': 92.01685185185184, 'Skin': 79.77571720232172, 'Small Intestine': 71.7519320855615, 'Spleen': 10.061029045643156, 'Stomach': 58.07813805013927, 'Testis': 0.8144204986149585, 'Thyroid': 135.176797856049, 'Uterus': 1.442593943661972, 'Vagina': 86.52345512820513} | FZR1 | MDQDYERRLLRQIVIQNENTMPRVTEMRRTLTPASSPVSSPSKHGDRFIPSRAGANWSVNFHRINENEKSPSQNRKAKDATSDNGKDGLAYSALLKNELLGAGIEKVQDPQTEDRRLQPSTPEKKGLFTYSLSTKRSSPDDGNDVSPYSLSPVSNKSQKLLRSPRKPTRKISKIPFKVLDAPELQDDFYLNLVDWSSLNVLSVGLGTCVYLWSACTSQVTRLCDLSVEGDSVTSVGWSERGNLVAVGTHKGFVQIWDAAAGKKLSMLEGHTARVGALAWNAEQLSSGSRDRMILQRDIRTPPLQSERRLQGHRQEVCGLKWSTDHQLLASGGNDNKLLVWNHSSLSPVQQYTEHLAAVKAIAWSPHQHGLLASGGGTADRCIRFWNTLTGQPLQCIDTGSQVCNLAWSKHANELVSTHGYSQNQILVWKYPSLTQVAKLTGHSYRVLYLAMSPDGEAIVTGAGDETLRFWNVFSKTRSTKVKWESVSVLNLFTRIR | Homo sapiens | Nucleus, Cytoplasm | Low tissue specificity | {'Ciliated cells': '15.1', 'Basal respiratory cells': '10.3', 'Club cells': '12.4', 'Ionocytes': '13.6', 'Mucus glandular cells': '10.5', 'Serous glandular cells': '6.5', 'Gastric mucus-secreting cells': '25.4', 'Proximal enterocytes': '13.9', 'Paneth cells': '12.7', 'Distal enterocytes': '20.8', 'Intestinal goblet cells': '19.0', 'Exocrine glandular cells': '-0.645', 'Basal prostatic cells': '13.1', 'Prostatic glandular cells': '9.1', 'Breast glandular cells': '0.694', 'Breast myoepithelial cells': '0.693', 'Glandular and luminal cells': '12.1', 'Secretory cells': '10.2', 'Basal keratinocytes': '17.9', 'Suprabasal keratinocytes': '21.7', 'Basal squamous epithelial cells': '6.2', 'Squamous epithelial cells': '12.1', 'Alveolar cells type 1': '0.205', 'Alveolar cells type 2': '-0.334', 'Salivary duct cells': '14.5', 'Ductal cells': '0.539', 'Hepatocytes': '0.294', 'Cholangiocytes': '21.0', 'Proximal tubular cells': '0.143', 'Distal tubular cells': '0.0', 'Collecting duct cells': '5.8', 'Mesothelial cells': '0.468', 'Sertoli cells': '-0.373', 'Granulosa cells': '12.6', 'Enteroendocrine cells': '17.1', 'Pancreatic endocrine cells': '10.2', 'Leydig cells': '-0.471', 'Excitatory neurons': '6.1', 'Inhibitory neurons': '8.7', 'Cone photoreceptor cells': '17.0', 'Rod photoreceptor cells': '16.3', 'Bipolar cells': '20.5', 'Horizontal cells': '24.5', 'Astrocytes': '6.2', 'Oligodendrocyte precursor cells': '6.1', 'Oligodendrocytes': '9.6', 'Microglial cells': '3.6', 'Muller glia cells': '8.2', 'Schwann cells': '0.004', 'Spermatogonia': '-0.192', 'Spermatocytes': '0.127', 'Early spermatids': '0.572', 'Late spermatids': '0.513', 'Oocytes': '22.1', 'Cytotrophoblasts': '21.6', 'Syncytiotrophoblasts': '43.6', 'Extravillous trophoblasts': '13.0', 'Endothelial cells': '9.4', 'Lymphatic endothelial cells': '5.6', 'Cardiomyocytes': '0.536', 'Skeletal myocytes': '-0.121', 'Smooth muscle cells': '9.6', 'Adipocytes': '7.6', 'Melanocytes': '0.162', 'Fibroblasts': '8.9', 'Peritubular cells': '-0.334', 'Endometrial stromal cells': '7.5', 'Ovarian stromal cells': '13.2', 'Undifferentiated cells': '12.9', 'T-cells': '13.0', 'B-cells': '15.2', 'Plasma cells': '11.5', 'Nk-cells': '12.4', 'Granulocytes': '9.5', 'Monocytes': '17.3', 'Macrophages': '11.1', 'Hofbauer cells': '14.8', 'Kupffer cells': '8.7', 'Dendritic cells': '13.6', 'Langerhans cells': '0.203', 'Erythroid cells': '0.118', 'Adipocytes (Subcutaneous)': 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Forms a ternary complex composed of ADAM10, CADH1 and EPHA4, | null | null | KLRG1, SPEF1, DLGAP5, AJAP1, RAPGEF2, RAB8B, PIP5K1C, PKP2, TRPV4, CTNNB1, CAV1, DDR1, TBC1D2, CTNNA1, JUP, CTNND1, PSEN1, LIMA1, CDH1, JUP, ADAM10, CADH1 , EPHA4, | null | null | null | null | Homodimer | null | 79.91949 | 0.474025 | 82.2 | 0.402923 | 1,605 |
P12830 | Q9UM11-2 | null | degron_data | CDH1 | MGPWSRSLSALLLLLQVSSWLCQEPEPCHPGFDAESYTFTVPRRHLERGRVLGRVNFEDCTGRQRTAYFSLDTRFKVGTDGVITVKRPLRFHNPQIHFLVYAWDSTYRKFSTKVTLNTVGHHHRPPPHQASVSGIQAELLTFPNSSPGLRRQKRDWVIPPISCPENEKGPFPKNLVQIKSNKDKEGKVFYSITGQGADTPPVGVFIIERETGWLKVTEPLDRERIATYTLFSHAVSSNGNAVEDPMEILITVTDQNDNKPEFTQEVFKGSVMEGALPGTSVMEVTATDADDDVNTYNAAIAYTILSQDPELPDKNMFTINRNTGVISVVTTGLDRESFPTYTLVVQAADLQGEGLSTTATAVITVTDTNDNPPIFNPTTYKGQVPENEANVVITTLKVTDADAPNTPAWEAVYTILNDDGGQFVVTTNPVNNDGILKTAKGLDFEAKQQYILHVAVTNVVPFEVSLTTSTATVTVDVLDVNEAPIFVPPEKRVEVSEDFGVGQEITSYTAQEPDTFMEQKITYRIWRDTANWLEINPDTGAISTRAELDREDFEHVKNSTYTALIIATDNGSPVATGTGTLLLILSDVNDNAPIPEPRTIFFCERNPKPQVINIIDADLPPNTSPFTAELTHGASANWTIQYNDPTQESIILKPKMALEVGDYKINLKLMDNQNKDQVTTLEVSVCDCEGAAGVCRKAQPVEAGLQIPAILGILGGILALLILILLLLLFLRRRAVVKEPLLPPEDDTRDNVYYYDEEGGGEEDQDFDLSQLHRGLDARPEVTRNDVAPTLMSVPRYLPRPANPDEIGNFIDENLKAADTDPTAPPYDSLLVFDYEGSGSEAASLSSLNSSESDKDQDYDYLNEWGNRFKKLADMYGGGEDD | Homo sapiens | Cell junction, adherens junction, Cell membrane, Endosome, Golgi apparatus, trans-Golgi network, Cytoplasm, Cell junction, desmosome | Tissue enhanced (parathyroid) | {'Ciliated cells': '119.1', 'Basal respiratory cells': '71.1', 'Club cells': '97.3', 'Ionocytes': '81.0', 'Mucus glandular cells': '155.0', 'Serous glandular cells': '67.8', 'Gastric mucus-secreting cells': '133.2', 'Proximal enterocytes': '140.9', 'Paneth cells': '125.1', 'Distal enterocytes': '307.5', 'Intestinal goblet cells': '173.5', 'Exocrine glandular cells': '-0.605', 'Basal prostatic cells': '68.3', 'Prostatic glandular cells': '186.7', 'Breast glandular cells': '0.773', 'Breast myoepithelial cells': '0.700', 'Glandular and luminal cells': '313.0', 'Secretory cells': '82.3', 'Basal keratinocytes': '102.5', 'Suprabasal keratinocytes': '162.6', 'Basal squamous epithelial cells': '51.0', 'Squamous epithelial cells': '106.9', 'Alveolar cells type 1': '0.437', 'Alveolar cells type 2': '0.706', 'Salivary duct cells': '95.9', 'Ductal cells': '0.541', 'Hepatocytes': '0.600', 'Cholangiocytes': '129.7', 'Proximal tubular cells': '0.042', 'Distal tubular cells': '0.0', 'Collecting duct cells': '143.9', 'Mesothelial cells': '0.799', 'Sertoli cells': '0.252', 'Granulosa cells': '12.9', 'Enteroendocrine cells': '92.4', 'Pancreatic endocrine cells': '78.1', 'Leydig cells': '0.264', 'Excitatory neurons': '0.7', 'Inhibitory neurons': '1.3', 'Cone photoreceptor cells': '0.0', 'Rod photoreceptor cells': '0.0', 'Bipolar cells': '0.2', 'Horizontal cells': '0.6', 'Astrocytes': '0.6', 'Oligodendrocyte precursor cells': '0.5', 'Oligodendrocytes': '29.9', 'Microglial cells': '0.9', 'Muller glia cells': '0.1', 'Schwann cells': '0.131', 'Spermatogonia': '0.392', 'Spermatocytes': '0.193', 'Early spermatids': '-0.217', 'Late spermatids': '-0.290', 'Oocytes': '16.9', 'Cytotrophoblasts': '119.2', 'Syncytiotrophoblasts': '45.0', 'Extravillous trophoblasts': '24.9', 'Endothelial cells': '6.1', 'Lymphatic endothelial cells': '0.4', 'Cardiomyocytes': '0.135', 'Skeletal myocytes': '0.107', 'Smooth muscle cells': '5.8', 'Adipocytes': '2.1', 'Melanocytes': '0.335', 'Fibroblasts': '6.5', 'Peritubular cells': '0.210', 'Endometrial stromal cells': '27.7', 'Ovarian stromal cells': '0.7', 'Undifferentiated cells': '101.6', 'T-cells': '2.9', 'B-cells': '4.4', 'Plasma cells': '6.1', 'Nk-cells': '0.0', 'Granulocytes': '8.4', 'Monocytes': '0.0', 'Macrophages': '6.0', 'Hofbauer cells': '4.3', 'Kupffer cells': '1.0', 'Dendritic cells': '5.9', 'Langerhans cells': '0.304', 'Erythroid cells': '0.036', 'Adipocytes (Subcutaneous)': '-0.081', 'Adipocytes (Visceral)': '-0.209', 'Breast glandular cells (progenitors)': '0.538', 'Adipocytes (Breast)': '-0.689', 'Colon enterocytes': '0.790', 'Colon enteroendocrine cells': '0.112', 'Enteric glia cells': '-0.048', 'Mitotic cells (Colon)': '0.299', 'Mitotic cells (Heart)': '0.120', 'Podocytes': '-0.118', 'Ascending Loop of Henle cells': '0.475', 'Intercalated cells': '0.212', 'Cholangiocyte': '0.090', 'NK-cells (Liver)': '-0.005', 'Respiratory ciliated cells': '-0.012', 'Mitotic cells (Lung)': '0.071', 'NK-cells (Lung)': '-0.266', 'B-cells (Lung)': '-0.296', 'Alpha cells': '0.270', 'Beta cells': '0.152', 'Prostate glandular cells': '0.764', 'Prostate basal glandular cells': '0.540', 'Urothelial cells': '0.205', 'Keratinocyte (other)': '0.510', 'Keratinocyte (granular)': '0.055', 'Hair cortex cells': '0.080', 'Inner root sheath cells': '0.131', 'Outer root sheath cells': '0.175', 'Sebaceous gland cells': '0.156', 'Eccrine sweat gland cells': '-0.207', 'Adipocytes (Skin)': '-0.244', 'Mitotic cells (Skin)': '0.442', 'Parietal cells': '0.654', 'Chief cells': '0.649', 'Gastric mucous cells': '0.781', 'Gastric enteroendocrine cells': '0.590', 'Mitotic cells (Stomach)': '0.445', 'Parafollicular cells': '0.173', 'Thyroid glandular cells': '0.865', 'Mitotic cells (Thyroid)': '-0.081', 'Adrenal cortex cells': '0.051', 'Adrenal medulla cells': '0.087', 'Mitotic cells (Adrenal gland)': '0.072', 'Minor salivary glandular cells': '0.371', 'Minor salivary gland ductal cells': '-0.142', 'Minor salivary gland basal cells': '0.582', 'Mitotic cells (Minor salivary gland)': '0.567', 'Adipocytes (Minor salivary gland)': '0.050', 'Somatotropes': '0.121', 'Lactotropes': '0.322', 'Gonadotropes': '0.330', 'Corticotropes': '0.180', 'Thyrotropes': '0.496', 'Undifferentiated cells (Pituitary gland)': '-0.108', 'Mitotic cells (Spleen)': '-0.228', 'Platelets': '-0.050', 'Erythrocytes': '-0.158', 'Hematopoietic stem cells': '-0.211', 'B-cells (Spleen)': '0.266', 'NK-cells (Spleen)': '0.309', 'Amygdala excitatory': '1.0', 'Cerebellar inhibitory': '0.9', 'Cge interneuron': '0.7', 'Deep-layer corticothalamic and 6b': '1.5', 'Deep-layer intratelencephalic': '0.7', 'Deep-layer near-projecting': '0.7', 'Eccentric medium spiny neuron': '0.6', 'Hippocampal ca1-3': '1.9', 'Hippocampal ca4': '1.2', 'Hippocampal dentate gyrus': '1.1', 'Lamp5-lhx6 and chandelier': '0.5', 'Lower rhombic lip': '0.8', 'Mammillary body': '0.6', 'Medium spiny neuron': '0.7', 'Mge interneuron': '1.7', 'Midbrain-derived inhibitory': '0.7', 'Miscellaneous': '0.9', 'Splatter': '3.8', 'Thalamic excitatory': '0.5', 'Upper rhombic lip': '0.8', 'Upper-layer intratelencephalic': '0.6', 'Astrocyte': '4.4', 'Bergmann glia': '0.2', 'Central nervous system macrophage': '0.6', 'Choroid plexus epithelial cell': '52.1', 'Committed oligodendrocyte precursor': '41.5', 'Ependymal cell': '4.8', 'Oligodendrocyte': '53.1', 'Oligodendrocyte precursor cell': '2.4', 'Endothelial cell': '0.7', 'Pericyte': '0.3', 'Vascular associated smooth muscle cell': '0.0', 'Fibroblast': '17.4', 'Leukocyte': '1.1', 'Basophil': '0.0', 'Eosinophil': '0.0', 'Neutrophil': '0.0', 'Classical monocyte': '0.0', 'Non-classical monocyte': '0.0', 'Intermediate monocyte': '0.0', 'T-reg': '2.3', 'GdT-cell': '0.0', 'MAIT T-cell': '0.0', 'Memory CD4 T-cell': '0.0', 'Naive CD4 T-cell': '0.1', 'Memory CD8 T-cell': '0.2', 'Naive CD8 T-cell': '0.3', 'Memory B-cell': '0.0', 'Naive B-cell': '0.1', 'Plasmacytoid DC': '46.6', 'Myeloid DC': '8.5', 'NK-cell': '0.1', 'Total PBMC': '0.7', 'Vd2 gdTCR': '0.0', 'Memory CD4 T-cell Th1\\/Th17': '0.1', 'Memory CD4 T-cell Th17': '0.2', 'Memory CD4 T-cell Th2': '2.9', 'Non-Vd2 gdTCR': '0.1', 'Memory CD4 T-cell Th1': '0.3', 'Memory CD4 T-cell TFH': '0.5', 'Terminal effector memory CD4 T-cell': '0.0', 'Central memory CD8 T-cell': '4.8', 'Effector memory CD8 T-cell': '0.0', 'Terminal effector memory CD8 T-cell': '0.6', 'Non-switched memory B-cell': '0.0', 'Plasmablast': '3.3', 'Switched memory B-cell': '0.0', 'Exhausted memory B-cell': '0.7', 'Progenitor cell': '2.3', 'Memory T-reg': '1.3', 'Naive CD4 T-cell activated': '0.3', 'Naive CD8 T-cell activated': '0.6', 'Naive T-reg': '0.1'} | 1O6S, 2O72, 2OMT, 2OMU, 2OMV, 2OMX, 2OMY, 2OMZ, 3FF7, 3FF8, 3L6X, 3L6Y, 4ZT1, 4ZTE, 6CXY, 6OLE, 6OLF, 6OLG, 6VEL, 7STZ, 8H62 | {'Adipose Tissue': 1.2125261088039867, 'Adrenal Gland': 0.1914223992248062, 'Bladder': 39.2033519047619, 'Blood': 1.340954264800861, 'Blood Vessel': 0.3121561692883895, 'Brain': 0.8550442199091597, 'Breast': 38.54918344226579, 'Cervix Uteri': 23.539115789473684, 'Colon': 43.41292142490372, 'Esophagus': 53.97513367404844, 'Fallopian Tube': 14.900277777777776, 'Heart': 0.119140469221835, 'Kidney': 25.040449438202245, 'Liver': 26.60802654867257, 'Lung': 35.447986366782004, 'Muscle': 0.1378936151930261, 'Nerve': 17.518468982229404, 'Ovary': 3.6515122222222223, 'Pancreas': 56.89676829268293, 'Pituitary': 24.68741660777385, 'Prostate': 61.279967346938776, 'Salivary Gland': 92.01685185185184, 'Skin': 79.77571720232172, 'Small Intestine': 71.7519320855615, 'Spleen': 10.061029045643156, 'Stomach': 58.07813805013927, 'Testis': 0.8144204986149585, 'Thyroid': 135.176797856049, 'Uterus': 1.442593943661972, 'Vagina': 86.52345512820513} | FZR1 | MDQDYERRLLRQIVIQNENTMPRVTEMRRTLTPASSPVSSPSKHGDRFIPSRAGANWSVNFHRINENEKSPSQNRKAKDATSDNGKDGLAYSALLKNELLGAGIEKVQDPQTEDRRLQPSTPEKKGLFTYSLSTKRSSPDDGNDVSPYSLSPVSNKSQKLLRSPRKPTRKISKIPFKVLDAPELQDDFYLNLVDWSSLNVLSVGLGTCVYLWSACTSQVTRLCDLSVEGDSVTSVGWSERGNLVAVGTHKGFVQIWDAAAGKKLSMLEGHTARVGALAWNAEQLSSGSRDRMILQRDIRTPPLQSERRLQGHRQEVCGLKWSTDHQLLASGGNDNKLLVWNHSSLSPVQQYTEHLAAVKAIAWSPHQHGLLASGGGTADRCIRFWNTLTGQPLQCIDTGSQVCNLAWSKHANELVSTHGYSQNQILVWKYPSLTQVAKLTGHSYRVLYLAMSPDGEAIVTGAGDETLRFWNVFSKTRSTKESVSVLNLFTRIR | Homo sapiens | Nucleus | Not found | {} | null | {'Adipose Tissue': 19.46810880398671, 'Adrenal Gland': 29.2876007751938, 'Bladder': 27.38285714285714, 'Blood': 19.547019375672768, 'Blood Vessel': 27.599573033707863, 'Brain': 26.95018433005299, 'Breast': 26.63632897603486, 'Cervix Uteri': 40.770526315789475, 'Colon': 23.282314505776636, 'Esophagus': 23.994503806228373, 'Fallopian Tube': 34.57222222222222, 'Heart': 8.733104529616725, 'Kidney': 17.97647191011236, 'Liver': 14.69487168141593, 'Lung': 26.58581314878893, 'Muscle': 11.545407222914072, 'Nerve': 34.77274636510501, 'Ovary': 42.36077777777778, 'Pancreas': 10.27298475609756, 'Pituitary': 58.10975265017668, 'Prostate': 34.24644897959183, 'Salivary Gland': 25.609259259259257, 'Skin': 32.51415257048093, 'Small Intestine': 25.308288770053473, 'Spleen': 28.76311203319502, 'Stomach': 17.90639554317549, 'Testis': 69.12493074792243, 'Thyroid': 48.03656814701378, 'Uterus': 41.83204225352112, 'Vagina': 35.41961538461538} | [39.93, 46.46, 52.9, 44.21, 41.4, 39.93, 35.91, 38.61, 36.44, 36.25, 34.86, 32.82, 32.01, 32.75, 31.69, 35.64, 36.35, 34.66, 33.32, 32.71, 35.01, 30.17, 37.05, 36.53, 48.19, 58.22, 64.94, 73.22, 78.33, 82.63, 85.79, 89.39, 87.89, 85.58, 83.93, 89.1, 89.27, 90.66, 87.86, 86.2, 82.97, 72.75, 73.3, 76.44, 82.38, 82.41, 79.49, 86.6, 76.32, 85.48, 88.69, 84.35, 87.75, 90.57, 88.72, 89.46, 87.48, 85.3, 81.72, 79.46, 77.26, 69.01, 67.1, 62.83, 67.71, 74.96, 82.95, 86.74, 86.35, 86.49, 84.6, 85.99, 85.64, 87.19, 89.23, 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Forms a ternary complex composed of ADAM10, CADH1 and EPHA4, | null | null | KLRG1, SPEF1, DLGAP5, AJAP1, RAPGEF2, RAB8B, PIP5K1C, PKP2, TRPV4, CTNNB1, CAV1, DDR1, TBC1D2, CTNNA1, JUP, CTNND1, PSEN1, LIMA1, CDH1, JUP, ADAM10, CADH1 , EPHA4, | null | null | null | null | Homodimer | null | 79.91949 | 0.474025 | null | null | 1,605 |
P12830 | Q9UM13 | null | degron_data | CDH1 | MGPWSRSLSALLLLLQVSSWLCQEPEPCHPGFDAESYTFTVPRRHLERGRVLGRVNFEDCTGRQRTAYFSLDTRFKVGTDGVITVKRPLRFHNPQIHFLVYAWDSTYRKFSTKVTLNTVGHHHRPPPHQASVSGIQAELLTFPNSSPGLRRQKRDWVIPPISCPENEKGPFPKNLVQIKSNKDKEGKVFYSITGQGADTPPVGVFIIERETGWLKVTEPLDRERIATYTLFSHAVSSNGNAVEDPMEILITVTDQNDNKPEFTQEVFKGSVMEGALPGTSVMEVTATDADDDVNTYNAAIAYTILSQDPELPDKNMFTINRNTGVISVVTTGLDRESFPTYTLVVQAADLQGEGLSTTATAVITVTDTNDNPPIFNPTTYKGQVPENEANVVITTLKVTDADAPNTPAWEAVYTILNDDGGQFVVTTNPVNNDGILKTAKGLDFEAKQQYILHVAVTNVVPFEVSLTTSTATVTVDVLDVNEAPIFVPPEKRVEVSEDFGVGQEITSYTAQEPDTFMEQKITYRIWRDTANWLEINPDTGAISTRAELDREDFEHVKNSTYTALIIATDNGSPVATGTGTLLLILSDVNDNAPIPEPRTIFFCERNPKPQVINIIDADLPPNTSPFTAELTHGASANWTIQYNDPTQESIILKPKMALEVGDYKINLKLMDNQNKDQVTTLEVSVCDCEGAAGVCRKAQPVEAGLQIPAILGILGGILALLILILLLLLFLRRRAVVKEPLLPPEDDTRDNVYYYDEEGGGEEDQDFDLSQLHRGLDARPEVTRNDVAPTLMSVPRYLPRPANPDEIGNFIDENLKAADTDPTAPPYDSLLVFDYEGSGSEAASLSSLNSSESDKDQDYDYLNEWGNRFKKLADMYGGGEDD | Homo sapiens | Cell junction, adherens junction, Cell membrane, Endosome, Golgi apparatus, trans-Golgi network, Cytoplasm, Cell junction, desmosome | Tissue enhanced (parathyroid) | {'Ciliated cells': '119.1', 'Basal respiratory cells': '71.1', 'Club cells': '97.3', 'Ionocytes': '81.0', 'Mucus glandular cells': '155.0', 'Serous glandular cells': '67.8', 'Gastric mucus-secreting cells': '133.2', 'Proximal enterocytes': '140.9', 'Paneth cells': '125.1', 'Distal enterocytes': '307.5', 'Intestinal goblet cells': '173.5', 'Exocrine glandular cells': '-0.605', 'Basal prostatic cells': '68.3', 'Prostatic glandular cells': '186.7', 'Breast glandular cells': '0.773', 'Breast myoepithelial cells': '0.700', 'Glandular and luminal cells': '313.0', 'Secretory cells': '82.3', 'Basal keratinocytes': '102.5', 'Suprabasal keratinocytes': '162.6', 'Basal squamous epithelial cells': '51.0', 'Squamous epithelial cells': '106.9', 'Alveolar cells type 1': '0.437', 'Alveolar cells type 2': '0.706', 'Salivary duct cells': '95.9', 'Ductal cells': '0.541', 'Hepatocytes': '0.600', 'Cholangiocytes': '129.7', 'Proximal tubular cells': '0.042', 'Distal tubular cells': '0.0', 'Collecting duct cells': '143.9', 'Mesothelial cells': '0.799', 'Sertoli cells': '0.252', 'Granulosa cells': '12.9', 'Enteroendocrine cells': '92.4', 'Pancreatic endocrine cells': '78.1', 'Leydig cells': '0.264', 'Excitatory neurons': '0.7', 'Inhibitory neurons': '1.3', 'Cone photoreceptor cells': '0.0', 'Rod photoreceptor cells': '0.0', 'Bipolar cells': '0.2', 'Horizontal cells': '0.6', 'Astrocytes': '0.6', 'Oligodendrocyte precursor cells': '0.5', 'Oligodendrocytes': '29.9', 'Microglial cells': '0.9', 'Muller glia cells': '0.1', 'Schwann cells': '0.131', 'Spermatogonia': '0.392', 'Spermatocytes': '0.193', 'Early spermatids': '-0.217', 'Late spermatids': '-0.290', 'Oocytes': '16.9', 'Cytotrophoblasts': '119.2', 'Syncytiotrophoblasts': '45.0', 'Extravillous trophoblasts': '24.9', 'Endothelial cells': '6.1', 'Lymphatic endothelial cells': '0.4', 'Cardiomyocytes': '0.135', 'Skeletal myocytes': '0.107', 'Smooth muscle cells': '5.8', 'Adipocytes': '2.1', 'Melanocytes': '0.335', 'Fibroblasts': '6.5', 'Peritubular cells': '0.210', 'Endometrial stromal cells': '27.7', 'Ovarian stromal cells': '0.7', 'Undifferentiated cells': '101.6', 'T-cells': '2.9', 'B-cells': '4.4', 'Plasma cells': '6.1', 'Nk-cells': '0.0', 'Granulocytes': '8.4', 'Monocytes': '0.0', 'Macrophages': '6.0', 'Hofbauer cells': '4.3', 'Kupffer cells': '1.0', 'Dendritic cells': '5.9', 'Langerhans cells': '0.304', 'Erythroid cells': '0.036', 'Adipocytes (Subcutaneous)': '-0.081', 'Adipocytes (Visceral)': '-0.209', 'Breast glandular cells (progenitors)': '0.538', 'Adipocytes (Breast)': '-0.689', 'Colon enterocytes': '0.790', 'Colon enteroendocrine cells': '0.112', 'Enteric glia cells': '-0.048', 'Mitotic cells (Colon)': '0.299', 'Mitotic cells (Heart)': '0.120', 'Podocytes': '-0.118', 'Ascending Loop of Henle cells': '0.475', 'Intercalated cells': '0.212', 'Cholangiocyte': '0.090', 'NK-cells (Liver)': '-0.005', 'Respiratory ciliated cells': '-0.012', 'Mitotic cells (Lung)': '0.071', 'NK-cells (Lung)': '-0.266', 'B-cells (Lung)': '-0.296', 'Alpha cells': '0.270', 'Beta cells': '0.152', 'Prostate glandular cells': '0.764', 'Prostate basal glandular cells': '0.540', 'Urothelial cells': '0.205', 'Keratinocyte (other)': '0.510', 'Keratinocyte (granular)': '0.055', 'Hair cortex cells': '0.080', 'Inner root sheath cells': '0.131', 'Outer root sheath cells': '0.175', 'Sebaceous gland cells': '0.156', 'Eccrine sweat gland cells': '-0.207', 'Adipocytes (Skin)': '-0.244', 'Mitotic cells (Skin)': '0.442', 'Parietal cells': '0.654', 'Chief cells': '0.649', 'Gastric mucous cells': '0.781', 'Gastric enteroendocrine cells': '0.590', 'Mitotic cells (Stomach)': '0.445', 'Parafollicular cells': '0.173', 'Thyroid glandular cells': '0.865', 'Mitotic cells (Thyroid)': '-0.081', 'Adrenal cortex cells': '0.051', 'Adrenal medulla cells': '0.087', 'Mitotic cells (Adrenal gland)': '0.072', 'Minor salivary glandular cells': '0.371', 'Minor salivary gland ductal cells': '-0.142', 'Minor salivary gland basal cells': '0.582', 'Mitotic cells (Minor salivary gland)': '0.567', 'Adipocytes (Minor salivary gland)': '0.050', 'Somatotropes': '0.121', 'Lactotropes': '0.322', 'Gonadotropes': '0.330', 'Corticotropes': '0.180', 'Thyrotropes': '0.496', 'Undifferentiated cells (Pituitary gland)': '-0.108', 'Mitotic cells (Spleen)': '-0.228', 'Platelets': '-0.050', 'Erythrocytes': '-0.158', 'Hematopoietic stem cells': '-0.211', 'B-cells (Spleen)': '0.266', 'NK-cells (Spleen)': '0.309', 'Amygdala excitatory': '1.0', 'Cerebellar inhibitory': '0.9', 'Cge interneuron': '0.7', 'Deep-layer corticothalamic and 6b': '1.5', 'Deep-layer intratelencephalic': '0.7', 'Deep-layer near-projecting': '0.7', 'Eccentric medium spiny neuron': '0.6', 'Hippocampal ca1-3': '1.9', 'Hippocampal ca4': '1.2', 'Hippocampal dentate gyrus': '1.1', 'Lamp5-lhx6 and chandelier': '0.5', 'Lower rhombic lip': '0.8', 'Mammillary body': '0.6', 'Medium spiny neuron': '0.7', 'Mge interneuron': '1.7', 'Midbrain-derived inhibitory': '0.7', 'Miscellaneous': '0.9', 'Splatter': '3.8', 'Thalamic excitatory': '0.5', 'Upper rhombic lip': '0.8', 'Upper-layer intratelencephalic': '0.6', 'Astrocyte': '4.4', 'Bergmann glia': '0.2', 'Central nervous system macrophage': '0.6', 'Choroid plexus epithelial cell': '52.1', 'Committed oligodendrocyte precursor': '41.5', 'Ependymal cell': '4.8', 'Oligodendrocyte': '53.1', 'Oligodendrocyte precursor cell': '2.4', 'Endothelial cell': '0.7', 'Pericyte': '0.3', 'Vascular associated smooth muscle cell': '0.0', 'Fibroblast': '17.4', 'Leukocyte': '1.1', 'Basophil': '0.0', 'Eosinophil': '0.0', 'Neutrophil': '0.0', 'Classical monocyte': '0.0', 'Non-classical monocyte': '0.0', 'Intermediate monocyte': '0.0', 'T-reg': '2.3', 'GdT-cell': '0.0', 'MAIT T-cell': '0.0', 'Memory CD4 T-cell': '0.0', 'Naive CD4 T-cell': '0.1', 'Memory CD8 T-cell': '0.2', 'Naive CD8 T-cell': '0.3', 'Memory B-cell': '0.0', 'Naive B-cell': '0.1', 'Plasmacytoid DC': '46.6', 'Myeloid DC': '8.5', 'NK-cell': '0.1', 'Total PBMC': '0.7', 'Vd2 gdTCR': '0.0', 'Memory CD4 T-cell Th1\\/Th17': '0.1', 'Memory CD4 T-cell Th17': '0.2', 'Memory CD4 T-cell Th2': '2.9', 'Non-Vd2 gdTCR': '0.1', 'Memory CD4 T-cell Th1': '0.3', 'Memory CD4 T-cell TFH': '0.5', 'Terminal effector memory CD4 T-cell': '0.0', 'Central memory CD8 T-cell': '4.8', 'Effector memory CD8 T-cell': '0.0', 'Terminal effector memory CD8 T-cell': '0.6', 'Non-switched memory B-cell': '0.0', 'Plasmablast': '3.3', 'Switched memory B-cell': '0.0', 'Exhausted memory B-cell': '0.7', 'Progenitor cell': '2.3', 'Memory T-reg': '1.3', 'Naive CD4 T-cell activated': '0.3', 'Naive CD8 T-cell activated': '0.6', 'Naive T-reg': '0.1'} | 1O6S, 2O72, 2OMT, 2OMU, 2OMV, 2OMX, 2OMY, 2OMZ, 3FF7, 3FF8, 3L6X, 3L6Y, 4ZT1, 4ZTE, 6CXY, 6OLE, 6OLF, 6OLG, 6VEL, 7STZ, 8H62 | {'Adipose Tissue': 1.2125261088039867, 'Adrenal Gland': 0.1914223992248062, 'Bladder': 39.2033519047619, 'Blood': 1.340954264800861, 'Blood Vessel': 0.3121561692883895, 'Brain': 0.8550442199091597, 'Breast': 38.54918344226579, 'Cervix Uteri': 23.539115789473684, 'Colon': 43.41292142490372, 'Esophagus': 53.97513367404844, 'Fallopian Tube': 14.900277777777776, 'Heart': 0.119140469221835, 'Kidney': 25.040449438202245, 'Liver': 26.60802654867257, 'Lung': 35.447986366782004, 'Muscle': 0.1378936151930261, 'Nerve': 17.518468982229404, 'Ovary': 3.6515122222222223, 'Pancreas': 56.89676829268293, 'Pituitary': 24.68741660777385, 'Prostate': 61.279967346938776, 'Salivary Gland': 92.01685185185184, 'Skin': 79.77571720232172, 'Small Intestine': 71.7519320855615, 'Spleen': 10.061029045643156, 'Stomach': 58.07813805013927, 'Testis': 0.8144204986149585, 'Thyroid': 135.176797856049, 'Uterus': 1.442593943661972, 'Vagina': 86.52345512820513} | ANAPC10 | MTTPNKTPPGADPKQLERTGTVREIGSQAVWSLSSCKPGFGVDQLRDDNLETYWQSDGSQPHLVNIQFRRKTTVKTLCIYADYKSDESYTPSKISVRVGNNFHNLQEIRQLELVEPSGWIHVPLTDNHKKPTRTFMIQIAVLANHQNGRDTHMRQIKIYTPVEESSIGKFPRCTTIDFMMYRSIR | Homo sapiens | null | Low tissue specificity | {'Ciliated cells': '23.3', 'Basal respiratory cells': '63.6', 'Club cells': '24.6', 'Ionocytes': '41.6', 'Mucus glandular cells': '10.1', 'Serous glandular cells': '11.3', 'Gastric mucus-secreting cells': '6.5', 'Proximal enterocytes': '16.3', 'Paneth cells': '14.1', 'Distal enterocytes': '8.3', 'Intestinal goblet cells': '15.9', 'Exocrine glandular cells': '-0.641', 'Basal prostatic cells': '16.9', 'Prostatic glandular cells': '11.2', 'Breast glandular cells': '0.466', 'Breast myoepithelial cells': '0.578', 'Glandular and luminal cells': '16.0', 'Secretory cells': '24.1', 'Basal keratinocytes': '16.0', 'Suprabasal keratinocytes': '18.3', 'Basal squamous epithelial cells': '11.1', 'Squamous epithelial cells': '12.7', 'Alveolar cells type 1': '0.043', 'Alveolar cells type 2': '-0.010', 'Salivary duct cells': '10.3', 'Ductal cells': '0.576', 'Hepatocytes': '0.285', 'Cholangiocytes': '7.6', 'Proximal tubular cells': '0.090', 'Distal tubular cells': '36.9', 'Collecting duct cells': '13.6', 'Mesothelial cells': '0.410', 'Sertoli cells': '-0.264', 'Granulosa cells': '25.4', 'Enteroendocrine cells': '15.1', 'Pancreatic endocrine cells': '28.9', 'Leydig cells': '-0.200', 'Excitatory neurons': '59.1', 'Inhibitory neurons': '55.6', 'Cone photoreceptor cells': '10.2', 'Rod photoreceptor cells': '5.9', 'Bipolar cells': '8.1', 'Horizontal cells': '5.7', 'Astrocytes': '29.7', 'Oligodendrocyte precursor cells': '52.4', 'Oligodendrocytes': '58.0', 'Microglial cells': '34.9', 'Muller glia cells': '17.4', 'Schwann cells': '0.136', 'Spermatogonia': '-0.015', 'Spermatocytes': '0.382', 'Early spermatids': '0.747', 'Late spermatids': '0.236', 'Oocytes': '59.6', 'Cytotrophoblasts': '40.1', 'Syncytiotrophoblasts': '31.4', 'Extravillous trophoblasts': '38.1', 'Endothelial cells': '20.4', 'Lymphatic endothelial cells': '23.5', 'Cardiomyocytes': '0.615', 'Skeletal myocytes': '-0.133', 'Smooth muscle cells': '21.3', 'Adipocytes': '26.8', 'Melanocytes': '0.159', 'Fibroblasts': '19.2', 'Peritubular cells': '-0.100', 'Endometrial stromal cells': '20.1', 'Ovarian stromal cells': '25.8', 'Undifferentiated cells': '17.7', 'T-cells': '15.6', 'B-cells': '15.6', 'Plasma cells': '11.1', 'Nk-cells': '19.1', 'Granulocytes': '20.1', 'Monocytes': '12.4', 'Macrophages': '15.8', 'Hofbauer cells': '33.7', 'Kupffer cells': '9.6', 'Dendritic cells': '14.7', 'Langerhans cells': '0.328', 'Erythroid cells': '0.149', 'Adipocytes (Subcutaneous)': '-0.399', 'Adipocytes (Visceral)': '-0.364', 'Breast glandular cells (progenitors)': '0.293', 'Adipocytes (Breast)': '-0.575', 'Colon enterocytes': '-0.268', 'Colon enteroendocrine cells': '0.318', 'Enteric glia cells': '0.451', 'Mitotic cells (Colon)': '-0.152', 'Mitotic cells (Heart)': '0.495', 'Podocytes': '0.129', 'Ascending Loop of Henle cells': '0.383', 'Intercalated cells': '0.142', 'Cholangiocyte': '0.410', 'NK-cells (Liver)': '-0.159', 'Respiratory ciliated cells': '0.022', 'Mitotic cells (Lung)': '0.091', 'NK-cells (Lung)': '-0.029', 'B-cells (Lung)': '-0.161', 'Alpha cells': '0.387', 'Beta cells': '0.250', 'Prostate glandular cells': '-0.289', 'Prostate basal glandular cells': '-0.017', 'Urothelial cells': '0.068', 'Keratinocyte (other)': '0.318', 'Keratinocyte (granular)': '-0.292', 'Hair cortex cells': '-0.084', 'Inner root sheath cells': '0.030', 'Outer root sheath cells': '0.255', 'Sebaceous gland cells': '0.014', 'Eccrine sweat gland cells': '0.068', 'Adipocytes (Skin)': '-0.267', 'Mitotic cells (Skin)': '0.403', 'Parietal cells': '-0.664', 'Chief cells': '-0.510', 'Gastric mucous cells': '-0.495', 'Gastric enteroendocrine cells': '-0.382', 'Mitotic cells (Stomach)': '-0.051', 'Parafollicular cells': '0.113', 'Thyroid glandular cells': '0.493', 'Mitotic cells (Thyroid)': '0.003', 'Adrenal cortex cells': '0.309', 'Adrenal medulla cells': '0.051', 'Mitotic cells (Adrenal gland)': '0.244', 'Minor salivary glandular cells': '0.377', 'Minor salivary gland ductal cells': '0.186', 'Minor salivary gland basal cells': '0.306', 'Mitotic cells (Minor salivary gland)': '0.337', 'Adipocytes (Minor salivary gland)': '0.222', 'Somatotropes': '-0.166', 'Lactotropes': '-0.120', 'Gonadotropes': '-0.010', 'Corticotropes': '-0.047', 'Thyrotropes': '0.191', 'Undifferentiated cells (Pituitary gland)': '0.313', 'Mitotic cells (Spleen)': '-0.231', 'Platelets': '-0.219', 'Erythrocytes': '-0.081', 'Hematopoietic stem cells': '-0.232', 'B-cells (Spleen)': '0.217', 'NK-cells (Spleen)': '0.306', 'Amygdala excitatory': '1.4', 'Cerebellar inhibitory': '2.8', 'Cge interneuron': '1.5', 'Deep-layer corticothalamic and 6b': '1.3', 'Deep-layer intratelencephalic': '1.2', 'Deep-layer near-projecting': '1.6', 'Eccentric medium spiny neuron': '1.3', 'Hippocampal ca1-3': '1.6', 'Hippocampal ca4': '1.1', 'Hippocampal dentate gyrus': '1.5', 'Lamp5-lhx6 and chandelier': '1.9', 'Lower rhombic lip': '2.5', 'Mammillary body': '1.5', 'Medium spiny neuron': '1.5', 'Mge interneuron': '1.6', 'Midbrain-derived inhibitory': '1.8', 'Miscellaneous': '1.1', 'Splatter': '2.1', 'Thalamic excitatory': '1.7', 'Upper rhombic lip': '1.5', 'Upper-layer intratelencephalic': '0.8', 'Astrocyte': '1.1', 'Bergmann glia': '2.2', 'Central nervous system macrophage': '1.0', 'Choroid plexus epithelial cell': '1.0', 'Committed oligodendrocyte precursor': '1.4', 'Ependymal cell': '0.8', 'Oligodendrocyte': '1.3', 'Oligodendrocyte precursor cell': '1.9', 'Endothelial cell': '1.2', 'Pericyte': '0.9', 'Vascular associated smooth muscle cell': '0.7', 'Fibroblast': '1.3', 'Leukocyte': '0.9', 'Basophil': '20.7', 'Eosinophil': '9.7', 'Neutrophil': '4.1', 'Classical monocyte': '3.7', 'Non-classical monocyte': '7.0', 'Intermediate monocyte': '16.4', 'T-reg': '24.8', 'GdT-cell': '13.0', 'MAIT T-cell': '17.4', 'Memory CD4 T-cell': '13.6', 'Naive CD4 T-cell': '9.4', 'Memory CD8 T-cell': '13.2', 'Naive CD8 T-cell': '6.6', 'Memory B-cell': '15.2', 'Naive B-cell': '6.8', 'Plasmacytoid DC': '30.8', 'Myeloid DC': '16.6', 'NK-cell': '7.1', 'Total PBMC': '21.3', 'Vd2 gdTCR': '28.0', 'Memory CD4 T-cell Th1\\/Th17': '8.9', 'Memory CD4 T-cell Th17': '8.1', 'Memory CD4 T-cell Th2': '8.0', 'Non-Vd2 gdTCR': '26.5', 'Memory CD4 T-cell Th1': '7.5', 'Memory CD4 T-cell TFH': '7.2', 'Terminal effector memory CD4 T-cell': '15.0', 'Central memory CD8 T-cell': '20.8', 'Effector memory CD8 T-cell': '17.5', 'Terminal effector memory CD8 T-cell': '22.2', 'Non-switched memory B-cell': '16.2', 'Plasmablast': '20.1', 'Switched memory B-cell': '20.5', 'Exhausted memory B-cell': '20.6', 'Progenitor cell': '12.8', 'Memory T-reg': '6.6', 'Naive CD4 T-cell activated': '8.9', 'Naive CD8 T-cell activated': '10.6', 'Naive T-reg': '9.0'} | 1JHJ, 4UI9, 5A31, 5G04, 5G05, 5KHR, 5KHU, 5L9T, 5L9U, 5LCW, 6Q6G, 6Q6H, 6TLJ, 6TM5, 6TNT, 7QE7, 8PKP, 8S4G, 8TAR, 8TAU | {'Adipose Tissue': 7.821908803986711, 'Adrenal Gland': 5.184391472868217, 'Bladder': 6.837095238095238, 'Blood': 2.9018791173304628, 'Blood Vessel': 9.019724344569289, 'Brain': 4.850145987887964, 'Breast': 8.41018082788671, 'Cervix Uteri': 8.406526315789472, 'Colon': 5.393255455712452, 'Esophagus': 5.464483737024222, 'Fallopian Tube': 7.963666666666667, 'Heart': 3.065893728222997, 'Kidney': 4.418258426966292, 'Liver': 2.531196460176991, 'Lung': 7.070570934256056, 'Muscle': 4.44274097135741, 'Nerve': 10.554345718901455, 'Ovary': 8.169838888888888, 'Pancreas': 2.181659451219512, 'Pituitary': 6.581254416961131, 'Prostate': 6.259244897959184, 'Salivary Gland': 5.212895061728395, 'Skin': 6.34014096185738, 'Small Intestine': 4.493893048128342, 'Spleen': 5.567120331950207, 'Stomach': 4.225016713091922, 'Testis': 12.378772853185597, 'Thyroid': 8.47322358346095, 'Uterus': 8.830669014084506, 'Vagina': 7.367320512820513} | [39.93, 46.46, 52.9, 44.21, 41.4, 39.93, 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0.04, 0.56, 0.29, 0.35, 0.01, 0.01, 0.11, 0.33, 0.0, 0.0, 0.0, 0.24, 0.1, 0.11, 0.57, 0.46, 0.48, 0.93, 0.37, 0.22, 0.72, 0.52, 0.33, 0.48, 0.53, 0.22, 0.64, 0.04, 0.42, 0.17, 0.01, 0.44, 0.09, 0.09, 0.09, 0.34, 0.01, 0.52, 0.0, 0.28, 0.37, 0.97, 0.79, 0.83, 0.66, 0.33, 0.14, 0.64, 0.02, 0.32, 0.02, 0.0, 0.06, 0.0, 0.0, 0.01, 0.29, 0.33, 0.05, 0.14, 0.68, 0.91, 0.09, 0.73, 0.15, 0.0, 0.08, 0.0, 0.1, 0.01, 0.0, 0.08, 0.0, 0.0, 0.19, 0.33, 0.33, 0.84, 0.5, 0.51, 0.52, 0.33, 0.7, 0.98, 0.76, 0.85, 0.61, 0.18, 0.74, 0.58, 0.8, 0.68, 0.54, 0.4, 0.78, 0.86, 0.59, 0.75, 1.0, 0.95] | null | Component of an E-cadherin/ catenin adhesion complex composed of at least E-cadherin/CDH1, beta-catenin/CTNNB1 or gamma-catenin/JUP, and potentially alpha-catenin/CTNNA1. Forms a ternary complex composed of ADAM10, CADH1 and EPHA4, | null | null | KLRG1, SPEF1, DLGAP5, AJAP1, RAPGEF2, RAB8B, PIP5K1C, PKP2, TRPV4, CTNNB1, CAV1, DDR1, TBC1D2, CTNNA1, JUP, CTNND1, PSEN1, LIMA1, CDH1, JUP, ADAM10, CADH1 , EPHA4, | null | null | null | null | Homodimer | null | 79.91949 | 0.474025 | 90.246108 | 0.367784 | 2,792 |
P12830 | Q9Y2I6 | null | degron_data | CDH1 | MGPWSRSLSALLLLLQVSSWLCQEPEPCHPGFDAESYTFTVPRRHLERGRVLGRVNFEDCTGRQRTAYFSLDTRFKVGTDGVITVKRPLRFHNPQIHFLVYAWDSTYRKFSTKVTLNTVGHHHRPPPHQASVSGIQAELLTFPNSSPGLRRQKRDWVIPPISCPENEKGPFPKNLVQIKSNKDKEGKVFYSITGQGADTPPVGVFIIERETGWLKVTEPLDRERIATYTLFSHAVSSNGNAVEDPMEILITVTDQNDNKPEFTQEVFKGSVMEGALPGTSVMEVTATDADDDVNTYNAAIAYTILSQDPELPDKNMFTINRNTGVISVVTTGLDRESFPTYTLVVQAADLQGEGLSTTATAVITVTDTNDNPPIFNPTTYKGQVPENEANVVITTLKVTDADAPNTPAWEAVYTILNDDGGQFVVTTNPVNNDGILKTAKGLDFEAKQQYILHVAVTNVVPFEVSLTTSTATVTVDVLDVNEAPIFVPPEKRVEVSEDFGVGQEITSYTAQEPDTFMEQKITYRIWRDTANWLEINPDTGAISTRAELDREDFEHVKNSTYTALIIATDNGSPVATGTGTLLLILSDVNDNAPIPEPRTIFFCERNPKPQVINIIDADLPPNTSPFTAELTHGASANWTIQYNDPTQESIILKPKMALEVGDYKINLKLMDNQNKDQVTTLEVSVCDCEGAAGVCRKAQPVEAGLQIPAILGILGGILALLILILLLLLFLRRRAVVKEPLLPPEDDTRDNVYYYDEEGGGEEDQDFDLSQLHRGLDARPEVTRNDVAPTLMSVPRYLPRPANPDEIGNFIDENLKAADTDPTAPPYDSLLVFDYEGSGSEAASLSSLNSSESDKDQDYDYLNEWGNRFKKLADMYGGGEDD | Homo sapiens | Cell junction, adherens junction, Cell membrane, Endosome, Golgi apparatus, trans-Golgi network, Cytoplasm, Cell junction, desmosome | Tissue enhanced (parathyroid) | {'Ciliated cells': '119.1', 'Basal respiratory cells': '71.1', 'Club cells': '97.3', 'Ionocytes': '81.0', 'Mucus glandular cells': '155.0', 'Serous glandular cells': '67.8', 'Gastric mucus-secreting cells': '133.2', 'Proximal enterocytes': '140.9', 'Paneth cells': '125.1', 'Distal enterocytes': '307.5', 'Intestinal goblet cells': '173.5', 'Exocrine glandular cells': '-0.605', 'Basal prostatic cells': '68.3', 'Prostatic glandular cells': '186.7', 'Breast glandular cells': '0.773', 'Breast myoepithelial cells': '0.700', 'Glandular and luminal cells': '313.0', 'Secretory cells': '82.3', 'Basal keratinocytes': '102.5', 'Suprabasal keratinocytes': '162.6', 'Basal squamous epithelial cells': '51.0', 'Squamous epithelial cells': '106.9', 'Alveolar cells type 1': '0.437', 'Alveolar cells type 2': '0.706', 'Salivary duct cells': '95.9', 'Ductal cells': '0.541', 'Hepatocytes': '0.600', 'Cholangiocytes': '129.7', 'Proximal tubular cells': '0.042', 'Distal tubular cells': '0.0', 'Collecting duct cells': '143.9', 'Mesothelial cells': '0.799', 'Sertoli cells': '0.252', 'Granulosa cells': '12.9', 'Enteroendocrine cells': '92.4', 'Pancreatic endocrine cells': '78.1', 'Leydig cells': '0.264', 'Excitatory neurons': '0.7', 'Inhibitory neurons': '1.3', 'Cone photoreceptor cells': '0.0', 'Rod photoreceptor cells': '0.0', 'Bipolar cells': '0.2', 'Horizontal cells': '0.6', 'Astrocytes': '0.6', 'Oligodendrocyte precursor cells': '0.5', 'Oligodendrocytes': '29.9', 'Microglial cells': '0.9', 'Muller glia cells': '0.1', 'Schwann cells': '0.131', 'Spermatogonia': '0.392', 'Spermatocytes': '0.193', 'Early spermatids': '-0.217', 'Late spermatids': '-0.290', 'Oocytes': '16.9', 'Cytotrophoblasts': '119.2', 'Syncytiotrophoblasts': '45.0', 'Extravillous trophoblasts': '24.9', 'Endothelial cells': '6.1', 'Lymphatic endothelial cells': '0.4', 'Cardiomyocytes': '0.135', 'Skeletal myocytes': '0.107', 'Smooth muscle cells': '5.8', 'Adipocytes': '2.1', 'Melanocytes': '0.335', 'Fibroblasts': '6.5', 'Peritubular cells': '0.210', 'Endometrial stromal cells': '27.7', 'Ovarian stromal cells': '0.7', 'Undifferentiated cells': '101.6', 'T-cells': '2.9', 'B-cells': '4.4', 'Plasma cells': '6.1', 'Nk-cells': '0.0', 'Granulocytes': '8.4', 'Monocytes': '0.0', 'Macrophages': '6.0', 'Hofbauer cells': '4.3', 'Kupffer cells': '1.0', 'Dendritic cells': '5.9', 'Langerhans cells': '0.304', 'Erythroid cells': '0.036', 'Adipocytes (Subcutaneous)': '-0.081', 'Adipocytes (Visceral)': '-0.209', 'Breast glandular cells (progenitors)': '0.538', 'Adipocytes (Breast)': '-0.689', 'Colon enterocytes': '0.790', 'Colon enteroendocrine cells': '0.112', 'Enteric glia cells': '-0.048', 'Mitotic cells (Colon)': '0.299', 'Mitotic cells (Heart)': '0.120', 'Podocytes': '-0.118', 'Ascending Loop of Henle cells': '0.475', 'Intercalated cells': '0.212', 'Cholangiocyte': '0.090', 'NK-cells (Liver)': '-0.005', 'Respiratory ciliated cells': '-0.012', 'Mitotic cells (Lung)': '0.071', 'NK-cells (Lung)': '-0.266', 'B-cells (Lung)': '-0.296', 'Alpha cells': '0.270', 'Beta cells': '0.152', 'Prostate glandular cells': '0.764', 'Prostate basal glandular cells': '0.540', 'Urothelial cells': '0.205', 'Keratinocyte (other)': '0.510', 'Keratinocyte (granular)': '0.055', 'Hair cortex cells': '0.080', 'Inner root sheath cells': '0.131', 'Outer root sheath cells': '0.175', 'Sebaceous gland cells': '0.156', 'Eccrine sweat gland cells': '-0.207', 'Adipocytes (Skin)': '-0.244', 'Mitotic cells (Skin)': '0.442', 'Parietal cells': '0.654', 'Chief cells': '0.649', 'Gastric mucous cells': '0.781', 'Gastric enteroendocrine cells': '0.590', 'Mitotic cells (Stomach)': '0.445', 'Parafollicular cells': '0.173', 'Thyroid glandular cells': '0.865', 'Mitotic cells (Thyroid)': '-0.081', 'Adrenal cortex cells': '0.051', 'Adrenal medulla cells': '0.087', 'Mitotic cells (Adrenal gland)': '0.072', 'Minor salivary glandular cells': '0.371', 'Minor salivary gland ductal cells': '-0.142', 'Minor salivary gland basal cells': '0.582', 'Mitotic cells (Minor salivary gland)': '0.567', 'Adipocytes (Minor salivary gland)': '0.050', 'Somatotropes': '0.121', 'Lactotropes': '0.322', 'Gonadotropes': '0.330', 'Corticotropes': '0.180', 'Thyrotropes': '0.496', 'Undifferentiated cells (Pituitary gland)': '-0.108', 'Mitotic cells (Spleen)': '-0.228', 'Platelets': '-0.050', 'Erythrocytes': '-0.158', 'Hematopoietic stem cells': '-0.211', 'B-cells (Spleen)': '0.266', 'NK-cells (Spleen)': '0.309', 'Amygdala excitatory': '1.0', 'Cerebellar inhibitory': '0.9', 'Cge interneuron': '0.7', 'Deep-layer corticothalamic and 6b': '1.5', 'Deep-layer intratelencephalic': '0.7', 'Deep-layer near-projecting': '0.7', 'Eccentric medium spiny neuron': '0.6', 'Hippocampal ca1-3': '1.9', 'Hippocampal ca4': '1.2', 'Hippocampal dentate gyrus': '1.1', 'Lamp5-lhx6 and chandelier': '0.5', 'Lower rhombic lip': '0.8', 'Mammillary body': '0.6', 'Medium spiny neuron': '0.7', 'Mge interneuron': '1.7', 'Midbrain-derived inhibitory': '0.7', 'Miscellaneous': '0.9', 'Splatter': '3.8', 'Thalamic excitatory': '0.5', 'Upper rhombic lip': '0.8', 'Upper-layer intratelencephalic': '0.6', 'Astrocyte': '4.4', 'Bergmann glia': '0.2', 'Central nervous system macrophage': '0.6', 'Choroid plexus epithelial cell': '52.1', 'Committed oligodendrocyte precursor': '41.5', 'Ependymal cell': '4.8', 'Oligodendrocyte': '53.1', 'Oligodendrocyte precursor cell': '2.4', 'Endothelial cell': '0.7', 'Pericyte': '0.3', 'Vascular associated smooth muscle cell': '0.0', 'Fibroblast': '17.4', 'Leukocyte': '1.1', 'Basophil': '0.0', 'Eosinophil': '0.0', 'Neutrophil': '0.0', 'Classical monocyte': '0.0', 'Non-classical monocyte': '0.0', 'Intermediate monocyte': '0.0', 'T-reg': '2.3', 'GdT-cell': '0.0', 'MAIT T-cell': '0.0', 'Memory CD4 T-cell': '0.0', 'Naive CD4 T-cell': '0.1', 'Memory CD8 T-cell': '0.2', 'Naive CD8 T-cell': '0.3', 'Memory B-cell': '0.0', 'Naive B-cell': '0.1', 'Plasmacytoid DC': '46.6', 'Myeloid DC': '8.5', 'NK-cell': '0.1', 'Total PBMC': '0.7', 'Vd2 gdTCR': '0.0', 'Memory CD4 T-cell Th1\\/Th17': '0.1', 'Memory CD4 T-cell Th17': '0.2', 'Memory CD4 T-cell Th2': '2.9', 'Non-Vd2 gdTCR': '0.1', 'Memory CD4 T-cell Th1': '0.3', 'Memory CD4 T-cell TFH': '0.5', 'Terminal effector memory CD4 T-cell': '0.0', 'Central memory CD8 T-cell': '4.8', 'Effector memory CD8 T-cell': '0.0', 'Terminal effector memory CD8 T-cell': '0.6', 'Non-switched memory B-cell': '0.0', 'Plasmablast': '3.3', 'Switched memory B-cell': '0.0', 'Exhausted memory B-cell': '0.7', 'Progenitor cell': '2.3', 'Memory T-reg': '1.3', 'Naive CD4 T-cell activated': '0.3', 'Naive CD8 T-cell activated': '0.6', 'Naive T-reg': '0.1'} | 1O6S, 2O72, 2OMT, 2OMU, 2OMV, 2OMX, 2OMY, 2OMZ, 3FF7, 3FF8, 3L6X, 3L6Y, 4ZT1, 4ZTE, 6CXY, 6OLE, 6OLF, 6OLG, 6VEL, 7STZ, 8H62 | {'Adipose Tissue': 1.2125261088039867, 'Adrenal Gland': 0.1914223992248062, 'Bladder': 39.2033519047619, 'Blood': 1.340954264800861, 'Blood Vessel': 0.3121561692883895, 'Brain': 0.8550442199091597, 'Breast': 38.54918344226579, 'Cervix Uteri': 23.539115789473684, 'Colon': 43.41292142490372, 'Esophagus': 53.97513367404844, 'Fallopian Tube': 14.900277777777776, 'Heart': 0.119140469221835, 'Kidney': 25.040449438202245, 'Liver': 26.60802654867257, 'Lung': 35.447986366782004, 'Muscle': 0.1378936151930261, 'Nerve': 17.518468982229404, 'Ovary': 3.6515122222222223, 'Pancreas': 56.89676829268293, 'Pituitary': 24.68741660777385, 'Prostate': 61.279967346938776, 'Salivary Gland': 92.01685185185184, 'Skin': 79.77571720232172, 'Small Intestine': 71.7519320855615, 'Spleen': 10.061029045643156, 'Stomach': 58.07813805013927, 'Testis': 0.8144204986149585, 'Thyroid': 135.176797856049, 'Uterus': 1.442593943661972, 'Vagina': 86.52345512820513} | NINL | MDEEENHYVSQLREVYSSCDTTGTGFLDRQELTQLCLKLHLEQQLPVLLQTLLGNDHFARVNFEEFKEGFVAVLSSNAGVRPSDEDSSSLESAASSAIPPKYVNGSKWYGRRSRPELCDAATEARRVPEQQTQASLKSHLWRSASLESVESPKSDEEAESTKEAQNELFEAQGQLQTWDSEDFGSPQKSCSPSFDTPESQIRGVWEELGVGSSGHLSEQELAVVCQSVGLQGLEKEELEDLFNKLDQDGDGKVSLEEFQLGLFSHEPALLLESSTRVKPSKAWSHYQVPEESGCHTTTTSSLVSLCSSLRLFSSIDDGSGFAFPDQVLAMWTQEGIQNGREILQSLDFSVDEKVNLLELTWALDNELMTVDSAVQQAALACYHQELSYQQGQVEQLARERDKARQDLERAEKRNLEFVKEMDDCHSTLEQLTEKKIKHLEQGYRERLSLLRSEVEAERELFWEQAHRQRAALEWDVGRLQAEEAGLREKLTLALKENSRLQKEIVEVVEKLSDSERLALKLQKDLEFVLKDKLEPQSAELLAQEERFAAVLKEYELKCRDLQDRNDELQAELEGLWARLPKNRHSPSWSPDGRRRQLPGLGPAGISFLGNSAPVSIETELMMEQVKEHYQDLRTQLETKVNYYEREIAALKRNFEKERKDMEQARRREVSVLEGQKADLEELHEKSQEVIWGLQEQLQDTARGPEPEQMGLAPCCTQALCGLALRHHSHLQQIRREAEAELSGELSGLGALPARRDLTLELEEPPQGPLPRGSQRSEQLELERALKLQPCASEKRAQMCVSLALEEEELELARGKRVDGPSLEAEMQALPKDGLVAGSGQEGTRGLLPLRPGCGERPLAWLAPGDGRESEEAAGAGPRRRQAQDTEATQSPAPAPAPASHGPSERWSRMQPCGVDGDIVPKEPEPFGASAAGLEQPGARELPLLGTERDASQTQPRMWEPPLRPAASCRGQAERLQAIQEERARSWSRGTQEQASEQQARAEGALEPGCHKHSVEVARRGSLPSHLQLADPQGSWQEQLAAPEEGETKIALEREKDDMETKLLHLEDVVRALEKHVDLRENDRLEFHRLSEENTLLKNDLGRVRQELEAAESTHDAQRKEIEVLKKDKEKACSEMEVLNRQNQNYKDQLSQLNVRVLQLGQEASTHQAQNEEHRVTIQMLTQSLEEVVRSGQQQSDQIQKLRVELECLNQEHQSLQLPWSELTQTLEESQDQVQGAHLRLRQAQAQHLQEVRLVPQDRVAELHRLLSLQGEQARRRLDAQREEHEKQLKATEERVEEAEMILKNMEMLLQEKVDKLKEQFEKNTKSDLLLKELYVENAHLVRALQATEEKQRGAEKQSRLLEEKVRALNKLVSRIAPAALSV | Homo sapiens | Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, Cytoplasm | Low tissue specificity | {'Ciliated cells': '4.4', 'Basal respiratory cells': '2.8', 'Club cells': '3.5', 'Ionocytes': '3.3', 'Mucus glandular cells': '3.9', 'Serous glandular cells': '0.2', 'Gastric mucus-secreting cells': '4.1', 'Proximal enterocytes': '0.7', 'Paneth cells': '1.4', 'Distal enterocytes': '0.3', 'Intestinal goblet cells': '1.6', 'Exocrine glandular cells': '-0.424', 'Basal prostatic cells': '1.7', 'Prostatic glandular cells': '14.6', 'Breast glandular cells': '0.677', 'Breast myoepithelial cells': '0.568', 'Glandular and luminal cells': '2.7', 'Secretory cells': '1.2', 'Basal keratinocytes': '2.3', 'Suprabasal keratinocytes': '0.5', 'Basal squamous epithelial cells': '5.1', 'Squamous epithelial cells': '4.1', 'Alveolar cells type 1': '0.143', 'Alveolar cells type 2': '0.259', 'Salivary duct cells': '8.9', 'Ductal cells': '0.551', 'Hepatocytes': '0.596', 'Cholangiocytes': '17.2', 'Proximal tubular cells': '0.258', 'Distal tubular cells': '3.1', 'Collecting duct cells': '5.8', 'Mesothelial cells': '0.727', 'Sertoli cells': '0.719', 'Granulosa cells': '9.7', 'Enteroendocrine cells': '5.1', 'Pancreatic endocrine cells': '3.4', 'Leydig cells': '0.509', 'Excitatory neurons': '7.1', 'Inhibitory neurons': '31.2', 'Cone photoreceptor cells': '10.2', 'Rod photoreceptor cells': '1.9', 'Bipolar cells': '2.4', 'Horizontal cells': '7.6', 'Astrocytes': '40.3', 'Oligodendrocyte precursor cells': '44.3', 'Oligodendrocytes': '18.0', 'Microglial cells': '11.6', 'Muller glia cells': '2.1', 'Schwann cells': '0.016', 'Spermatogonia': '0.288', 'Spermatocytes': '-0.067', 'Early spermatids': '-0.566', 'Late spermatids': '-0.657', 'Oocytes': '0.7', 'Cytotrophoblasts': '2.8', 'Syncytiotrophoblasts': '1.3', 'Extravillous trophoblasts': '1.5', 'Endothelial cells': '2.9', 'Lymphatic endothelial cells': '16.0', 'Cardiomyocytes': '0.534', 'Skeletal myocytes': '0.587', 'Smooth muscle cells': '3.7', 'Adipocytes': '1.0', 'Melanocytes': '-0.017', 'Fibroblasts': '4.6', 'Peritubular cells': '0.553', 'Endometrial stromal cells': '6.3', 'Ovarian stromal cells': '13.1', 'Undifferentiated cells': '2.7', 'T-cells': '1.1', 'B-cells': '0.6', 'Plasma cells': '1.4', 'Nk-cells': '1.4', 'Granulocytes': '0.0', 'Monocytes': '0.0', 'Macrophages': '1.0', 'Hofbauer cells': '1.7', 'Kupffer cells': '2.8', 'Dendritic cells': '0.8', 'Langerhans cells': '0.095', 'Erythroid cells': '0.112', 'Adipocytes (Subcutaneous)': '-0.194', 'Adipocytes (Visceral)': '-0.270', 'Breast glandular cells (progenitors)': '0.466', 'Adipocytes (Breast)': '-0.492', 'Colon enterocytes': '-0.197', 'Colon enteroendocrine cells': '0.256', 'Enteric glia cells': '0.280', 'Mitotic cells (Colon)': '-0.217', 'Mitotic cells (Heart)': '0.202', 'Podocytes': '-0.126', 'Ascending Loop of Henle cells': '0.536', 'Intercalated cells': '0.050', 'Cholangiocyte': '-0.080', 'NK-cells (Liver)': '0.240', 'Respiratory ciliated cells': '0.070', 'Mitotic cells (Lung)': '0.074', 'NK-cells (Lung)': '-0.161', 'B-cells (Lung)': '-0.099', 'Alpha cells': '0.443', 'Beta cells': '0.374', 'Prostate glandular cells': '0.211', 'Prostate basal glandular cells': '0.274', 'Urothelial cells': '0.099', 'Keratinocyte (other)': '-0.387', 'Keratinocyte (granular)': '-0.459', 'Hair cortex cells': '0.314', 'Inner root sheath cells': '0.357', 'Outer root sheath cells': '0.650', 'Sebaceous gland cells': '0.290', 'Eccrine sweat gland cells': '0.408', 'Adipocytes (Skin)': '0.300', 'Mitotic cells (Skin)': '0.257', 'Parietal cells': '-0.475', 'Chief cells': '-0.550', 'Gastric mucous cells': '-0.337', 'Gastric enteroendocrine cells': '-0.388', 'Mitotic cells (Stomach)': '-0.073', 'Parafollicular cells': '0.102', 'Thyroid glandular cells': '0.286', 'Mitotic cells (Thyroid)': '-0.054', 'Adrenal cortex cells': '0.277', 'Adrenal medulla cells': '-0.051', 'Mitotic cells (Adrenal gland)': '0.198', 'Minor salivary glandular cells': '0.362', 'Minor 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Forms a ternary complex composed of ADAM10, CADH1 and EPHA4, | null | null | KLRG1, SPEF1, DLGAP5, AJAP1, RAPGEF2, RAB8B, PIP5K1C, PKP2, TRPV4, CTNNB1, CAV1, DDR1, TBC1D2, CTNNA1, JUP, CTNND1, PSEN1, LIMA1, CDH1, JUP, ADAM10, CADH1 , EPHA4, | null | null | null | null | Homodimer | null | 79.91949 | 0.474025 | 66.506013 | 0.644305 | 245 |
P12830 | Q9Y2M0 | null | degron_data | CDH1 | MGPWSRSLSALLLLLQVSSWLCQEPEPCHPGFDAESYTFTVPRRHLERGRVLGRVNFEDCTGRQRTAYFSLDTRFKVGTDGVITVKRPLRFHNPQIHFLVYAWDSTYRKFSTKVTLNTVGHHHRPPPHQASVSGIQAELLTFPNSSPGLRRQKRDWVIPPISCPENEKGPFPKNLVQIKSNKDKEGKVFYSITGQGADTPPVGVFIIERETGWLKVTEPLDRERIATYTLFSHAVSSNGNAVEDPMEILITVTDQNDNKPEFTQEVFKGSVMEGALPGTSVMEVTATDADDDVNTYNAAIAYTILSQDPELPDKNMFTINRNTGVISVVTTGLDRESFPTYTLVVQAADLQGEGLSTTATAVITVTDTNDNPPIFNPTTYKGQVPENEANVVITTLKVTDADAPNTPAWEAVYTILNDDGGQFVVTTNPVNNDGILKTAKGLDFEAKQQYILHVAVTNVVPFEVSLTTSTATVTVDVLDVNEAPIFVPPEKRVEVSEDFGVGQEITSYTAQEPDTFMEQKITYRIWRDTANWLEINPDTGAISTRAELDREDFEHVKNSTYTALIIATDNGSPVATGTGTLLLILSDVNDNAPIPEPRTIFFCERNPKPQVINIIDADLPPNTSPFTAELTHGASANWTIQYNDPTQESIILKPKMALEVGDYKINLKLMDNQNKDQVTTLEVSVCDCEGAAGVCRKAQPVEAGLQIPAILGILGGILALLILILLLLLFLRRRAVVKEPLLPPEDDTRDNVYYYDEEGGGEEDQDFDLSQLHRGLDARPEVTRNDVAPTLMSVPRYLPRPANPDEIGNFIDENLKAADTDPTAPPYDSLLVFDYEGSGSEAASLSSLNSSESDKDQDYDYLNEWGNRFKKLADMYGGGEDD | Homo sapiens | Cell junction, adherens junction, Cell membrane, Endosome, Golgi apparatus, trans-Golgi network, Cytoplasm, Cell junction, desmosome | Tissue enhanced (parathyroid) | {'Ciliated cells': '119.1', 'Basal respiratory cells': '71.1', 'Club cells': '97.3', 'Ionocytes': '81.0', 'Mucus glandular cells': '155.0', 'Serous glandular cells': '67.8', 'Gastric mucus-secreting cells': '133.2', 'Proximal enterocytes': '140.9', 'Paneth cells': '125.1', 'Distal enterocytes': '307.5', 'Intestinal goblet cells': '173.5', 'Exocrine glandular cells': '-0.605', 'Basal prostatic cells': '68.3', 'Prostatic glandular cells': '186.7', 'Breast glandular cells': '0.773', 'Breast myoepithelial cells': '0.700', 'Glandular and luminal cells': '313.0', 'Secretory cells': '82.3', 'Basal keratinocytes': '102.5', 'Suprabasal keratinocytes': '162.6', 'Basal squamous epithelial cells': '51.0', 'Squamous epithelial cells': '106.9', 'Alveolar cells type 1': '0.437', 'Alveolar cells type 2': '0.706', 'Salivary duct cells': '95.9', 'Ductal cells': '0.541', 'Hepatocytes': '0.600', 'Cholangiocytes': '129.7', 'Proximal tubular cells': '0.042', 'Distal tubular cells': '0.0', 'Collecting duct cells': '143.9', 'Mesothelial cells': '0.799', 'Sertoli cells': '0.252', 'Granulosa cells': '12.9', 'Enteroendocrine cells': '92.4', 'Pancreatic endocrine cells': '78.1', 'Leydig cells': '0.264', 'Excitatory neurons': '0.7', 'Inhibitory neurons': '1.3', 'Cone photoreceptor cells': '0.0', 'Rod photoreceptor cells': '0.0', 'Bipolar cells': '0.2', 'Horizontal cells': '0.6', 'Astrocytes': '0.6', 'Oligodendrocyte precursor cells': '0.5', 'Oligodendrocytes': '29.9', 'Microglial cells': '0.9', 'Muller glia cells': '0.1', 'Schwann cells': '0.131', 'Spermatogonia': '0.392', 'Spermatocytes': '0.193', 'Early spermatids': '-0.217', 'Late spermatids': '-0.290', 'Oocytes': '16.9', 'Cytotrophoblasts': '119.2', 'Syncytiotrophoblasts': '45.0', 'Extravillous trophoblasts': '24.9', 'Endothelial cells': '6.1', 'Lymphatic endothelial cells': '0.4', 'Cardiomyocytes': '0.135', 'Skeletal myocytes': '0.107', 'Smooth muscle cells': '5.8', 'Adipocytes': '2.1', 'Melanocytes': '0.335', 'Fibroblasts': '6.5', 'Peritubular cells': '0.210', 'Endometrial stromal cells': '27.7', 'Ovarian stromal cells': '0.7', 'Undifferentiated cells': '101.6', 'T-cells': '2.9', 'B-cells': '4.4', 'Plasma cells': '6.1', 'Nk-cells': '0.0', 'Granulocytes': '8.4', 'Monocytes': '0.0', 'Macrophages': '6.0', 'Hofbauer cells': '4.3', 'Kupffer cells': '1.0', 'Dendritic cells': '5.9', 'Langerhans cells': '0.304', 'Erythroid cells': '0.036', 'Adipocytes (Subcutaneous)': '-0.081', 'Adipocytes (Visceral)': '-0.209', 'Breast glandular cells (progenitors)': '0.538', 'Adipocytes (Breast)': '-0.689', 'Colon enterocytes': '0.790', 'Colon enteroendocrine cells': '0.112', 'Enteric glia cells': '-0.048', 'Mitotic cells (Colon)': '0.299', 'Mitotic cells (Heart)': '0.120', 'Podocytes': '-0.118', 'Ascending Loop of Henle cells': '0.475', 'Intercalated cells': '0.212', 'Cholangiocyte': '0.090', 'NK-cells (Liver)': '-0.005', 'Respiratory ciliated cells': '-0.012', 'Mitotic cells (Lung)': '0.071', 'NK-cells (Lung)': '-0.266', 'B-cells (Lung)': '-0.296', 'Alpha cells': '0.270', 'Beta cells': '0.152', 'Prostate glandular cells': '0.764', 'Prostate basal glandular cells': '0.540', 'Urothelial cells': '0.205', 'Keratinocyte (other)': '0.510', 'Keratinocyte (granular)': '0.055', 'Hair cortex cells': '0.080', 'Inner root sheath cells': '0.131', 'Outer root sheath cells': '0.175', 'Sebaceous gland cells': '0.156', 'Eccrine sweat gland cells': '-0.207', 'Adipocytes (Skin)': '-0.244', 'Mitotic cells (Skin)': '0.442', 'Parietal cells': '0.654', 'Chief cells': '0.649', 'Gastric mucous cells': '0.781', 'Gastric enteroendocrine cells': '0.590', 'Mitotic cells (Stomach)': '0.445', 'Parafollicular cells': '0.173', 'Thyroid glandular cells': '0.865', 'Mitotic cells (Thyroid)': '-0.081', 'Adrenal cortex cells': '0.051', 'Adrenal medulla cells': '0.087', 'Mitotic cells (Adrenal gland)': '0.072', 'Minor salivary glandular cells': '0.371', 'Minor salivary gland ductal cells': '-0.142', 'Minor salivary gland basal cells': '0.582', 'Mitotic cells (Minor salivary gland)': '0.567', 'Adipocytes (Minor salivary gland)': '0.050', 'Somatotropes': '0.121', 'Lactotropes': '0.322', 'Gonadotropes': '0.330', 'Corticotropes': '0.180', 'Thyrotropes': '0.496', 'Undifferentiated cells (Pituitary gland)': '-0.108', 'Mitotic cells (Spleen)': '-0.228', 'Platelets': '-0.050', 'Erythrocytes': '-0.158', 'Hematopoietic stem cells': '-0.211', 'B-cells (Spleen)': '0.266', 'NK-cells (Spleen)': '0.309', 'Amygdala excitatory': '1.0', 'Cerebellar inhibitory': '0.9', 'Cge interneuron': '0.7', 'Deep-layer corticothalamic and 6b': '1.5', 'Deep-layer intratelencephalic': '0.7', 'Deep-layer near-projecting': '0.7', 'Eccentric medium spiny neuron': '0.6', 'Hippocampal ca1-3': '1.9', 'Hippocampal ca4': '1.2', 'Hippocampal dentate gyrus': '1.1', 'Lamp5-lhx6 and chandelier': '0.5', 'Lower rhombic lip': '0.8', 'Mammillary body': '0.6', 'Medium spiny neuron': '0.7', 'Mge interneuron': '1.7', 'Midbrain-derived inhibitory': '0.7', 'Miscellaneous': '0.9', 'Splatter': '3.8', 'Thalamic excitatory': '0.5', 'Upper rhombic lip': '0.8', 'Upper-layer intratelencephalic': '0.6', 'Astrocyte': '4.4', 'Bergmann glia': '0.2', 'Central nervous system macrophage': '0.6', 'Choroid plexus epithelial cell': '52.1', 'Committed oligodendrocyte precursor': '41.5', 'Ependymal cell': '4.8', 'Oligodendrocyte': '53.1', 'Oligodendrocyte precursor cell': '2.4', 'Endothelial cell': '0.7', 'Pericyte': '0.3', 'Vascular associated smooth muscle cell': '0.0', 'Fibroblast': '17.4', 'Leukocyte': '1.1', 'Basophil': '0.0', 'Eosinophil': '0.0', 'Neutrophil': '0.0', 'Classical monocyte': '0.0', 'Non-classical monocyte': '0.0', 'Intermediate monocyte': '0.0', 'T-reg': '2.3', 'GdT-cell': '0.0', 'MAIT T-cell': '0.0', 'Memory CD4 T-cell': '0.0', 'Naive CD4 T-cell': '0.1', 'Memory CD8 T-cell': '0.2', 'Naive CD8 T-cell': '0.3', 'Memory B-cell': '0.0', 'Naive B-cell': '0.1', 'Plasmacytoid DC': '46.6', 'Myeloid DC': '8.5', 'NK-cell': '0.1', 'Total PBMC': '0.7', 'Vd2 gdTCR': '0.0', 'Memory CD4 T-cell Th1\\/Th17': '0.1', 'Memory CD4 T-cell Th17': '0.2', 'Memory CD4 T-cell Th2': '2.9', 'Non-Vd2 gdTCR': '0.1', 'Memory CD4 T-cell Th1': '0.3', 'Memory CD4 T-cell TFH': '0.5', 'Terminal effector memory CD4 T-cell': '0.0', 'Central memory CD8 T-cell': '4.8', 'Effector memory CD8 T-cell': '0.0', 'Terminal effector memory CD8 T-cell': '0.6', 'Non-switched memory B-cell': '0.0', 'Plasmablast': '3.3', 'Switched memory B-cell': '0.0', 'Exhausted memory B-cell': '0.7', 'Progenitor cell': '2.3', 'Memory T-reg': '1.3', 'Naive CD4 T-cell activated': '0.3', 'Naive CD8 T-cell activated': '0.6', 'Naive T-reg': '0.1'} | 1O6S, 2O72, 2OMT, 2OMU, 2OMV, 2OMX, 2OMY, 2OMZ, 3FF7, 3FF8, 3L6X, 3L6Y, 4ZT1, 4ZTE, 6CXY, 6OLE, 6OLF, 6OLG, 6VEL, 7STZ, 8H62 | {'Adipose Tissue': 1.2125261088039867, 'Adrenal Gland': 0.1914223992248062, 'Bladder': 39.2033519047619, 'Blood': 1.340954264800861, 'Blood Vessel': 0.3121561692883895, 'Brain': 0.8550442199091597, 'Breast': 38.54918344226579, 'Cervix Uteri': 23.539115789473684, 'Colon': 43.41292142490372, 'Esophagus': 53.97513367404844, 'Fallopian Tube': 14.900277777777776, 'Heart': 0.119140469221835, 'Kidney': 25.040449438202245, 'Liver': 26.60802654867257, 'Lung': 35.447986366782004, 'Muscle': 0.1378936151930261, 'Nerve': 17.518468982229404, 'Ovary': 3.6515122222222223, 'Pancreas': 56.89676829268293, 'Pituitary': 24.68741660777385, 'Prostate': 61.279967346938776, 'Salivary Gland': 92.01685185185184, 'Skin': 79.77571720232172, 'Small Intestine': 71.7519320855615, 'Spleen': 10.061029045643156, 'Stomach': 58.07813805013927, 'Testis': 0.8144204986149585, 'Thyroid': 135.176797856049, 'Uterus': 1.442593943661972, 'Vagina': 86.52345512820513} | FAN1 | MMSEGKPPDKKRPRRSLSISKNKKKASNSIISCFNNAPPAKLACPVCSKMVPRYDLNRHLDEMCANNDFVQVDPGQVGLINSNVSMVDLTSVTLEDVTPKKSPPPKTNLTPGQSDSAKREVKQKISPYFKSNDVVCKNQDELRNRSVKVICLGSLASKLSRKYVKAKKSIDKDEEFAGSSPQSSKSTVVKSLIDNSSEIEDEDQILENSSQKENVFKCDSLKEECIPEHMVRGSKIMEAESQKATRECEKSALTPGFSDNAIMLFSPDFTLRNTLKSTSEDSLVKQECIKEVVEKREACHCEEVKMTVASEAKIQLSDSEAKSHSSADDASAWSNIQEAPLQDDSCLNNDIPHSIPLEQGSSCNGPGQTTGHPYYLRSFLVVLKTVLENEDDMLLFDEQEKGIVTKFYQLSATGQKLYVRLFQRKLSWIKMTKLEYEEIALDLTPVIEELTNAGFLQTESELQELSEVLELLSAPELKSLAKTFHLVNPNGQKQQLVDAFLKLAKQRSVCTWGKNKPGIGAVILKRAKALAGQSVRICKGPRAVFSRILLLFSLTDSMEDEDAACGGQGQLSTVLLVNLGRMEFPSYTINRKTHIFQDRDDLIRYAAATHMLSDISSAMANGNWEEAKELAQCAKRDWNRLKNHPSLRCHEDLPLFLRCFTVGWIYTRILSRFVEILQRLHMYEEAVRELESLLSQRIYCPDSRGRWWDRLALNLHQHLKRLEPTIKCITEGLADPEVRTGHRLSLYQRAVRLRESPSCKKFKHLFQQLPEMAVQDVKHVTITGRLCPQRGMCKSVFVMEAGEAADPTTVLCSVEELALAHYRRSGFDQGIHGEGSTFSTLYGLLLWDIIFMDGIPDVFRNACQAFPLDLCTDSFFTSRRPALEARLQLIHDAPEESLRAWVAATWHEQEGRVASLVSWDRFTSLQQAQDLVSCLGGPVLSGVCRHLAADFRHCRGGLPDLVVWNSQSRHFKLVEVKGPNDRLSHKQMIWLAELQKLGAEVEVCHVVAVGAKSQSLS | Homo sapiens | Nucleus | Low tissue specificity | {'Ciliated cells': '10.7', 'Basal respiratory cells': '4.6', 'Club cells': '12.5', 'Ionocytes': '9.9', 'Mucus glandular cells': '16.3', 'Serous glandular cells': '13.8', 'Gastric mucus-secreting cells': '10.6', 'Proximal enterocytes': '4.5', 'Paneth cells': '8.0', 'Distal enterocytes': '7.2', 'Intestinal goblet cells': '13.8', 'Exocrine glandular cells': '-0.366', 'Basal prostatic cells': '12.1', 'Prostatic glandular cells': '33.1', 'Breast glandular cells': '0.517', 'Breast myoepithelial cells': '0.498', 'Glandular and luminal cells': '10.6', 'Secretory cells': '9.1', 'Basal keratinocytes': '7.9', 'Suprabasal keratinocytes': '5.6', 'Basal squamous epithelial cells': '10.4', 'Squamous epithelial cells': '6.7', 'Alveolar cells type 1': '0.036', 'Alveolar cells type 2': '-0.002', 'Salivary duct cells': '15.2', 'Ductal cells': '0.447', 'Hepatocytes': '0.528', 'Cholangiocytes': '1.9', 'Proximal tubular cells': '0.184', 'Distal tubular cells': '3.1', 'Collecting duct cells': '13.6', 'Mesothelial cells': '0.318', 'Sertoli cells': '-0.344', 'Granulosa cells': '15.1', 'Enteroendocrine cells': '13.1', 'Pancreatic endocrine cells': '1.7', 'Leydig cells': '-0.333', 'Excitatory neurons': '22.9', 'Inhibitory neurons': '24.4', 'Cone photoreceptor cells': '32.3', 'Rod photoreceptor cells': '34.3', 'Bipolar cells': '23.7', 'Horizontal cells': '30.2', 'Astrocytes': '20.1', 'Oligodendrocyte precursor cells': '12.7', 'Oligodendrocytes': '41.2', 'Microglial cells': '14.3', 'Muller glia cells': '13.6', 'Schwann cells': '0.087', 'Spermatogonia': '0.000', 'Spermatocytes': '0.364', 'Early spermatids': '0.528', 'Late spermatids': '0.335', 'Oocytes': '1.5', 'Cytotrophoblasts': '8.8', 'Syncytiotrophoblasts': '6.5', 'Extravillous trophoblasts': '2.6', 'Endothelial cells': '11.9', 'Lymphatic endothelial cells': '9.8', 'Cardiomyocytes': '0.690', 'Skeletal myocytes': '-0.268', 'Smooth muscle cells': '9.1', 'Adipocytes': '10.2', 'Melanocytes': '0.085', 'Fibroblasts': '10.3', 'Peritubular cells': '-0.083', 'Endometrial stromal cells': '13.8', 'Ovarian stromal cells': '13.8', 'Undifferentiated cells': '10.6', 'T-cells': '7.4', 'B-cells': '6.4', 'Plasma cells': '8.9', 'Nk-cells': '6.6', 'Granulocytes': '8.9', 'Monocytes': '3.3', 'Macrophages': '5.6', 'Hofbauer cells': '4.3', 'Kupffer cells': '6.0', 'Dendritic cells': '2.4', 'Langerhans cells': '0.215', 'Erythroid cells': '-0.132', 'Adipocytes (Subcutaneous)': '0.075', 'Adipocytes (Visceral)': '-0.089', 'Breast glandular cells (progenitors)': '0.478', 'Adipocytes (Breast)': '-0.423', 'Colon enterocytes': '-0.031', 'Colon enteroendocrine cells': '0.113', 'Enteric glia cells': '-0.279', 'Mitotic cells (Colon)': '-0.077', 'Mitotic cells (Heart)': '0.437', 'Podocytes': '-0.131', 'Ascending Loop of Henle cells': '0.592', 'Intercalated cells': '0.085', 'Cholangiocyte': '0.165', 'NK-cells (Liver)': '-0.234', 'Respiratory ciliated cells': '0.077', 'Mitotic cells (Lung)': '0.113', 'NK-cells (Lung)': '-0.025', 'B-cells (Lung)': '-0.100', 'Alpha cells': '0.379', 'Beta cells': '0.313', 'Prostate glandular cells': '0.279', 'Prostate basal glandular cells': '0.434', 'Urothelial cells': '0.175', 'Keratinocyte (other)': '0.203', 'Keratinocyte (granular)': '-0.079', 'Hair cortex cells': '-0.083', 'Inner root sheath cells': '-0.013', 'Outer root sheath cells': '0.094', 'Sebaceous gland cells': '0.089', 'Eccrine sweat gland cells': '0.005', 'Adipocytes (Skin)': '-0.091', 'Mitotic cells (Skin)': '0.361', 'Parietal cells': '-0.380', 'Chief cells': '-0.359', 'Gastric mucous cells': '-0.292', 'Gastric enteroendocrine cells': '-0.283', 'Mitotic cells (Stomach)': '0.068', 'Parafollicular cells': '0.089', 'Thyroid glandular cells': '0.371', 'Mitotic cells (Thyroid)': '-0.050', 'Adrenal cortex cells': '0.586', 'Adrenal medulla cells': '0.002', 'Mitotic cells (Adrenal gland)': '0.462', 'Minor salivary glandular cells': '0.296', 'Minor salivary gland ductal cells': '0.453', 'Minor salivary gland basal cells': '-0.150', 'Mitotic cells (Minor salivary gland)': '-0.225', 'Adipocytes (Minor salivary gland)': '-0.009', 'Somatotropes': '0.283', 'Lactotropes': '0.186', 'Gonadotropes': '0.102', 'Corticotropes': '-0.064', 'Thyrotropes': '0.135', 'Undifferentiated cells (Pituitary gland)': '0.027', 'Mitotic cells (Spleen)': '0.016', 'Platelets': '-0.181', 'Erythrocytes': '-0.065', 'Hematopoietic stem cells': '-0.255', 'B-cells (Spleen)': '0.241', 'NK-cells (Spleen)': '0.231', 'Amygdala excitatory': '37.0', 'Cerebellar inhibitory': '45.2', 'Cge interneuron': '50.5', 'Deep-layer corticothalamic and 6b': '36.3', 'Deep-layer intratelencephalic': '41.3', 'Deep-layer near-projecting': '32.6', 'Eccentric medium spiny neuron': '33.1', 'Hippocampal ca1-3': '41.1', 'Hippocampal ca4': '38.3', 'Hippocampal dentate gyrus': '41.4', 'Lamp5-lhx6 and chandelier': '38.3', 'Lower rhombic lip': '82.2', 'Mammillary body': '52.3', 'Medium spiny neuron': '32.8', 'Mge interneuron': '37.8', 'Midbrain-derived inhibitory': '38.0', 'Miscellaneous': '38.6', 'Splatter': '47.7', 'Thalamic excitatory': '48.7', 'Upper rhombic lip': '48.8', 'Upper-layer intratelencephalic': '37.4', 'Astrocyte': '49.9', 'Bergmann glia': '37.9', 'Central nervous system macrophage': '44.1', 'Choroid plexus epithelial cell': '51.2', 'Committed oligodendrocyte precursor': '51.4', 'Ependymal cell': '36.5', 'Oligodendrocyte': '83.9', 'Oligodendrocyte precursor cell': '52.8', 'Endothelial cell': '30.5', 'Pericyte': '23.8', 'Vascular associated smooth muscle cell': '16.9', 'Fibroblast': '39.0', 'Leukocyte': '25.3', 'Basophil': '0.7', 'Eosinophil': '0.0', 'Neutrophil': '0.2', 'Classical monocyte': '6.7', 'Non-classical monocyte': '10.1', 'Intermediate monocyte': '0.2', 'T-reg': '0.7', 'GdT-cell': '1.4', 'MAIT T-cell': '0.7', 'Memory CD4 T-cell': '1.2', 'Naive CD4 T-cell': '45.3', 'Memory CD8 T-cell': '0.7', 'Naive CD8 T-cell': '36.8', 'Memory B-cell': '1.2', 'Naive B-cell': '23.3', 'Plasmacytoid DC': '1.7', 'Myeloid DC': '1.0', 'NK-cell': '21.0', 'Total PBMC': '1.1', 'Vd2 gdTCR': '1.2', 'Memory CD4 T-cell TFH': '33.2', 'Memory CD4 T-cell Th2': '37.0', 'Memory CD4 T-cell Th17': '33.0', 'Memory CD4 T-cell Th1\\/Th17': '33.1', 'Non-Vd2 gdTCR': '0.8', 'Memory CD4 T-cell Th1': '32.2', 'Terminal effector memory CD4 T-cell': '1.6', 'Central memory CD8 T-cell': '1.1', 'Effector memory CD8 T-cell': '0.8', 'Terminal effector memory CD8 T-cell': '0.5', 'Switched memory B-cell': '0.5', 'Plasmablast': '1.4', 'Non-switched memory B-cell': '2.1', 'Exhausted memory B-cell': '0.4', 'Progenitor cell': '3.2', 'Memory T-reg': '23.1', 'Naive CD4 T-cell activated': '19.6', 'Naive CD8 T-cell activated': '19.6', 'Naive T-reg': '37.1'} | 4REA, 4REB, 4REC, 4RI8, 4RI9, 4RIA, 4RIB, 4RIC, 4RID, 4RY3 | {'Adipose Tissue': 8.615357142857142, 'Adrenal Gland': 8.992126744186047, 'Bladder': 12.963190476190476, 'Blood': 3.785463928955867, 'Blood Vessel': 9.719731835205993, 'Brain': 9.417120439061318, 'Breast': 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E-cadherin/CDH1, beta-catenin/CTNNB1 or gamma-catenin/JUP, and potentially alpha-catenin/CTNNA1. Forms a ternary complex composed of ADAM10, CADH1 and EPHA4, | null | null | KLRG1, SPEF1, DLGAP5, AJAP1, RAPGEF2, RAB8B, PIP5K1C, PKP2, TRPV4, CTNNB1, CAV1, DDR1, TBC1D2, CTNNA1, JUP, CTNND1, PSEN1, LIMA1, CDH1, JUP, ADAM10, CADH1 , EPHA4, | null | null | null | null | Homodimer | null | 79.91949 | 0.474025 | 69.866303 | 0.504985 | 501 |
P14373 | O00750 | 22128329 | UbiNet, UbiBrowser | TRIM27 | MASGSVAECLQQETTCPVCLQYFAEPMMLDCGHNICCACLARCWGTAETNVSCPQCRETFPQRHMRPNRHLANVTQLVKQLRTERPSGPGGEMGVCEKHREPLKLYCEEDQMPICVVCDRSREHRGHSVLPLEEAVEGFKEQIQNQLDHLKRVKDLKKRRRAQGEQARAELLSLTQMEREKIVWEFEQLYHSLKEHEYRLLARLEELDLAIYNSINGAITQFSCNISHLSSLIAQLEEKQQQPTRELLQDIGDTLSRAERIRIPEPWITPPDLQEKIHIFAQKCLFLTESLKQFTEKMQSDMEKIQELREAQLYSVDVTLDPDTAYPSLILSDNLRQVRYSYLQQDLPDNPERFNLFPCVLGSPCFIAGRHYWEVEVGDKAKWTIGVCEDSVCRKGGVTSAPQNGFWAVSLWYGKEYWALTSPMTALPLRTPLQRVGIFLDYDAGEVSFYNVTERCHTFTFSHATFCGPVRPYFSLSYSGGKSAAPLIICPMSGIDGFSGHVGNHGHSMETSP | Homo sapiens | Nucleus, Cytoplasm, Nucleus, PML body, Early endosome, Mitochondrion | Low tissue specificity | {'Ciliated cells': '25.1', 'Basal respiratory cells': '27.3', 'Club cells': '24.7', 'Ionocytes': '23.2', 'Mucus glandular cells': '21.7', 'Serous glandular cells': '33.5', 'Gastric mucus-secreting cells': '23.6', 'Proximal enterocytes': '20.1', 'Paneth cells': '20.0', 'Distal enterocytes': '15.1', 'Intestinal goblet cells': '37.0', 'Exocrine glandular cells': '-0.693', 'Basal prostatic cells': '43.6', 'Prostatic glandular cells': '43.5', 'Breast glandular cells': '0.696', 'Breast myoepithelial cells': '0.544', 'Glandular and luminal cells': '29.8', 'Secretory cells': '37.3', 'Basal keratinocytes': '26.5', 'Suprabasal keratinocytes': '15.7', 'Basal squamous epithelial cells': '34.1', 'Squamous epithelial cells': '21.9', 'Alveolar cells type 1': '-0.038', 'Alveolar cells type 2': '-0.408', 'Salivary duct cells': '18.1', 'Ductal cells': '0.480', 'Hepatocytes': '0.177', 'Cholangiocytes': '22.9', 'Proximal tubular cells': '0.232', 'Distal tubular cells': '18.4', 'Collecting duct cells': '27.2', 'Mesothelial cells': '0.392', 'Sertoli cells': '0.703', 'Granulosa cells': '19.2', 'Enteroendocrine cells': '31.0', 'Pancreatic endocrine cells': '18.7', 'Leydig cells': '0.636', 'Excitatory neurons': '13.0', 'Inhibitory neurons': '12.8', 'Cone photoreceptor cells': '13.6', 'Rod photoreceptor cells': '11.3', 'Bipolar cells': '10.1', 'Horizontal cells': '7.6', 'Astrocytes': '11.1', 'Oligodendrocyte precursor cells': '17.9', 'Oligodendrocytes': '18.4', 'Microglial cells': '16.1', 'Muller glia cells': '12.1', 'Schwann cells': '0.026', 'Spermatogonia': '0.420', 'Spermatocytes': '-0.042', 'Early spermatids': '-0.589', 'Late spermatids': '-0.706', 'Oocytes': '13.2', 'Cytotrophoblasts': '48.8', 'Syncytiotrophoblasts': '50.5', 'Extravillous trophoblasts': '58.8', 'Endothelial cells': '27.6', 'Lymphatic endothelial cells': '18.3', 'Cardiomyocytes': '0.444', 'Skeletal myocytes': '-0.371', 'Smooth muscle cells': '19.7', 'Adipocytes': '20.7', 'Melanocytes': '-0.177', 'Fibroblasts': '22.4', 'Peritubular cells': '0.559', 'Endometrial stromal cells': '27.3', 'Ovarian stromal cells': '24.5', 'Undifferentiated cells': '29.3', 'T-cells': '28.5', 'B-cells': '33.6', 'Plasma cells': '50.4', 'Nk-cells': '25.7', 'Granulocytes': '27.4', 'Monocytes': '32.5', 'Macrophages': '29.6', 'Hofbauer cells': '38.9', 'Kupffer cells': '31.1', 'Dendritic cells': '32.8', 'Langerhans cells': '0.075', 'Erythroid cells': '-0.057', 'Adipocytes (Subcutaneous)': '-0.199', 'Adipocytes (Visceral)': '-0.372', 'Breast glandular cells (progenitors)': '0.493', 'Adipocytes (Breast)': '-0.659', 'Colon enterocytes': '-0.039', 'Colon enteroendocrine cells': '0.155', 'Enteric glia cells': '0.411', 'Mitotic cells (Colon)': '0.069', 'Mitotic cells (Heart)': '0.481', 'Podocytes': '-0.080', 'Ascending Loop of Henle cells': '0.332', 'Intercalated cells': '-0.067', 'Cholangiocyte': '0.283', 'NK-cells (Liver)': '-0.293', 'Respiratory ciliated cells': '0.036', 'Mitotic cells (Lung)': '-0.109', 'NK-cells (Lung)': '0.295', 'B-cells (Lung)': '0.112', 'Alpha cells': '0.335', 'Beta cells': '0.170', 'Prostate glandular cells': '0.251', 'Prostate basal glandular cells': '0.383', 'Urothelial cells': '0.310', 'Keratinocyte (other)': '-0.109', 'Keratinocyte (granular)': '-0.354', 'Hair cortex cells': '0.029', 'Inner root sheath cells': '0.037', 'Outer root sheath cells': '0.284', 'Sebaceous gland cells': '0.136', 'Eccrine sweat gland cells': '0.208', 'Adipocytes (Skin)': '0.020', 'Mitotic cells (Skin)': '0.110', 'Parietal cells': '-0.236', 'Chief cells': '-0.025', 'Gastric mucous cells': '0.098', 'Gastric enteroendocrine cells': '0.091', 'Mitotic cells (Stomach)': '0.263', 'Parafollicular cells': '0.070', 'Thyroid glandular cells': '0.072', 'Mitotic cells (Thyroid)': '0.055', 'Adrenal cortex cells': '0.312', 'Adrenal medulla cells': '-0.104', 'Mitotic cells (Adrenal gland)': '-0.086', 'Minor salivary glandular cells': '0.517', 'Minor salivary gland ductal cells': '0.287', 'Minor salivary gland basal cells': '-0.017', 'Mitotic cells (Minor salivary gland)': '0.010', 'Adipocytes (Minor salivary gland)': '0.057', 'Somatotropes': '0.482', 'Lactotropes': '0.227', 'Gonadotropes': '0.066', 'Corticotropes': '0.019', 'Thyrotropes': '0.026', 'Undifferentiated cells (Pituitary gland)': '-0.250', 'Mitotic cells (Spleen)': '-0.238', 'Platelets': '-0.171', 'Erythrocytes': '-0.096', 'Hematopoietic stem cells': '-0.313', 'B-cells (Spleen)': '0.377', 'NK-cells (Spleen)': '0.278', 'Amygdala excitatory': '29.4', 'Cerebellar inhibitory': '15.3', 'Cge interneuron': '27.6', 'Deep-layer corticothalamic and 6b': '29.3', 'Deep-layer intratelencephalic': '31.8', 'Deep-layer near-projecting': '34.8', 'Eccentric medium spiny neuron': '27.3', 'Hippocampal ca1-3': '26.5', 'Hippocampal ca4': '28.4', 'Hippocampal dentate gyrus': '29.8', 'Lamp5-lhx6 and chandelier': '22.8', 'Lower rhombic lip': '32.2', 'Mammillary body': '18.8', 'Medium spiny neuron': '22.8', 'Mge interneuron': '26.6', 'Midbrain-derived inhibitory': '28.4', 'Miscellaneous': '30.0', 'Splatter': '27.8', 'Thalamic excitatory': '23.9', 'Upper rhombic lip': '24.1', 'Upper-layer intratelencephalic': '28.8', 'Astrocyte': '26.3', 'Bergmann glia': '25.2', 'Central nervous system macrophage': '78.3', 'Choroid plexus epithelial cell': '42.9', 'Committed oligodendrocyte precursor': '33.8', 'Ependymal cell': '20.3', 'Oligodendrocyte': '36.0', 'Oligodendrocyte precursor cell': '32.2', 'Endothelial cell': '58.5', 'Pericyte': '33.4', 'Vascular associated smooth muscle cell': '31.7', 'Fibroblast': '43.5', 'Leukocyte': '58.3', 'Basophil': '20.3', 'Eosinophil': '2.5', 'Neutrophil': '51.3', 'Classical monocyte': '17.4', 'Non-classical monocyte': '33.2', 'Intermediate monocyte': '36.3', 'T-reg': '19.6', 'GdT-cell': '7.2', 'MAIT T-cell': '29.7', 'Memory CD4 T-cell': '10.6', 'Naive CD4 T-cell': '29.7', 'Memory CD8 T-cell': '5.6', 'Naive CD8 T-cell': '28.3', 'Memory B-cell': '7.1', 'Naive B-cell': '18.7', 'Plasmacytoid DC': '27.3', 'Myeloid DC': '30.5', 'NK-cell': '26.2', 'Total PBMC': '23.0', 'Vd2 gdTCR': '19.2', 'Memory CD4 T-cell Th1\\/Th17': '22.6', 'Memory CD4 T-cell Th17': '23.3', 'Memory CD4 T-cell Th2': '23.3', 'Non-Vd2 gdTCR': '18.3', 'Memory CD4 T-cell Th1': '23.8', 'Memory CD4 T-cell TFH': '24.9', 'Terminal effector memory CD4 T-cell': '26.8', 'Central memory CD8 T-cell': '23.4', 'Effector memory CD8 T-cell': '21.7', 'Terminal effector memory CD8 T-cell': '14.3', 'Non-switched memory B-cell': '22.5', 'Plasmablast': '44.1', 'Switched memory B-cell': '25.7', 'Exhausted memory B-cell': '13.9', 'Progenitor cell': '20.6', 'Memory T-reg': '26.0', 'Naive CD4 T-cell activated': '55.5', 'Naive CD8 T-cell activated': '61.3', 'Naive T-reg': '32.5'} | null | {'Adipose Tissue': 30.51002491694352, 'Adrenal Gland': 28.42209302325581, 'Bladder': 42.15761904761904, 'Blood': 47.71387405812702, 'Blood Vessel': 35.17883895131086, 'Brain': 17.082769114307343, 'Breast': 35.04257080610022, 'Cervix Uteri': 56.090526315789475, 'Colon': 26.715078305519896, 'Esophagus': 25.588709342560552, 'Fallopian Tube': 54.83888888888889, 'Heart': 12.228174216027876, 'Kidney': 20.893404494382025, 'Liver': 28.784889380530977, 'Lung': 43.63569204152249, 'Muscle': 13.141891656288918, 'Nerve': 43.2170436187399, 'Ovary': 50.49094444444445, 'Pancreas': 26.43318292682927, 'Pituitary': 49.52038869257951, 'Prostate': 47.70363265306122, 'Salivary Gland': 32.1683950617284, 'Skin': 30.310514648977335, 'Small Intestine': 34.5279679144385, 'Spleen': 56.557759336099586, 'Stomach': 26.06833704735376, 'Testis': 26.19157894736842, 'Thyroid': 45.41816232771823, 'Uterus': 52.2319014084507, 'Vagina': 36.81769230769231} | PIK3C2B | MSSTQGNGEHWKSLESVGISRKELAMAEALQMEYDALSRLRHDKEENRAKQNADPSLISWDEPGVDFYSKPAGRRTDLKLLRGLSGSDPTLNYNSLSPQEGPPNHSTSQGPQPGSDPWPKGSLSGDYLYIFDGSDGGVSSSPGPGDIEGSCKKLSPPPLPPRASIWDTPPLPPRKGSPSSSKISQPSDINTFSLVEQLPGKLLEHRILEEEEVLGGGGQGRLLGSVDYDGINDAITRLNLKSTYDAEMLRDATRGWKEGRGPLDFSKDTSGKPVARSKTMPPQVPPRTYASRYGNRKNATPGKNRRISAAPVGSRPHTVANGHELFEVSEERDEEVAAFCHMLDILRSGSDIQDYFLTGYVWSAVTPSPEHLGDEVNLKVTVLCDRLQEALTFTCNCSSTVDLLIYQTLCYTHDDLRNVDVGDFVLKPCGLEEFLQNKHALGSHEYIQYCRKFDIDIRLQLMEQKVVRSDLARTVNDDQSPSTLNYLVHLQERPVKQTISRQALSLLFDTYHNEVDAFLLADGDFPLKADRVVQSVKAICNALAAVETPEITSALNQLPPCPSRMQPKIQKDPSVLAVRENREKVVEALTAAILDLVELYCNTFNADFQTAVPGSRKHDLVQEACHFARSLAFTVYATHRIPIIWATSYEDFYLSCSLSHGGKELCSPLQTRRAHFSKYLFHLIVWDQQICFPVQVNRLPRETLLCATLYALPIPPPGSSSEANKQRRVPEALGWVTTPLFNFRQVLTCGRKLLGLWPATQENPSARWSAPNFHQPDSVILQIDFPTSAFDIKFTSPPGDKFSPRYEFGSLREEDQRKLKDIMQKESLYWLTDADKKRLWEKRYYCHSEVSSLPLVLASAPSWEWACLPDIYVLLKQWTHMNHQDALGLLHATFPDQEVRRMAVQWIGSLSDAELLDYLPQLVQALKYECYLDSPLVRFLLKRAVSDLRVTHYFFWLLKDGLKDSQFSIRYQYLLAALLCCCGKGLREEFNRQCWLVNALAKLAQQVREAAPSARQGILRTGLEEVKQFFALNGSCRLPLSPSLLVKGIVPRDCSYFNSNAVPLKLSFQNVDPLGENIRVIFKCGDDLRQDMLTLQMIRIMSKIWVQEGLDMRMVIFRCFSTGRGRGMVEMIPNAETLRKIQVEHGVTGSFKDRPLADWLQKHNPGEDEYEKAVENFIYSCAGCCVATYVLGICDRHNDNIMLKTTGHMFHIDFGRFLGHAQMFGNIKRDRAPFVFTSDMAYVINGGDKPSSRFHDFVDLCCQAYNLIRKHTHLFLNLLGLMLSCGIPELSDLEDLKYVYDALRPQDTEANATTYFTRLIESSLGSVATKLNFFIHNLAQMKFTGSDDRLTLSFASRTHTLKSSGRISDVFLCRHEKIFHPNKGYIYVVKVMRENTHEATYIQRTFEEFQELHNKLRLLFPSSHLPSFPSRFVIGRSRGEAVAERRREELNGYIWHLIHAPPEVAECDLVYTFFHPLPRDEKAMGTSPAPKSSDGTWARPVGKVGGEVKLSISYKNNKLFIMVMHIRGLQLLQDGNDPDPYVKIYLLPDPQKTTKRKTKVARKTCNPTYNEMLVYDGIPKGDLQQRELQLSVLSEQGFWENVLLGEVNIRLRELDLAQEKTGWFALGSRSHGTL | Homo sapiens | Microsome, Cell membrane, Cytoplasm, cytosol, Nucleus, Endoplasmic reticulum | Low tissue specificity | {'Ciliated cells': '5.6', 'Basal respiratory cells': '7.8', 'Club cells': '11.9', 'Ionocytes': '10.7', 'Mucus glandular cells': '5.2', 'Serous glandular cells': '7.4', 'Gastric mucus-secreting cells': '24.2', 'Proximal enterocytes': '13.9', 'Paneth cells': '11.0', 'Distal enterocytes': '29.4', 'Intestinal goblet cells': '27.3', 'Exocrine glandular cells': '-0.374', 'Basal prostatic cells': '5.0', 'Prostatic glandular cells': '5.8', 'Breast glandular cells': '0.120', 'Breast myoepithelial cells': '0.199', 'Glandular and luminal cells': '2.3', 'Secretory cells': '1.6', 'Basal keratinocytes': '6.4', 'Suprabasal keratinocytes': '12.8', 'Basal squamous epithelial cells': '2.2', 'Squamous epithelial cells': '8.9', 'Alveolar cells type 1': '0.141', 'Alveolar cells type 2': '-0.347', 'Salivary duct cells': '3.4', 'Ductal cells': '0.439', 'Hepatocytes': '0.393', 'Cholangiocytes': '7.6', 'Proximal tubular cells': '-0.007', 'Distal tubular cells': '0.0', 'Collecting duct cells': '3.9', 'Mesothelial cells': '0.089', 'Sertoli cells': '0.338', 'Granulosa cells': '1.4', 'Enteroendocrine cells': '12.2', 'Pancreatic endocrine cells': '0.0', 'Leydig cells': '0.502', 'Excitatory neurons': '13.8', 'Inhibitory neurons': '21.8', 'Cone photoreceptor cells': '0.0', 'Rod photoreceptor cells': '0.7', 'Bipolar cells': '16.6', 'Horizontal cells': '15.1', 'Astrocytes': '15.2', 'Oligodendrocyte precursor cells': '22.2', 'Oligodendrocytes': '103.8', 'Microglial cells': '25.9', 'Muller glia cells': '2.8', 'Schwann cells': '0.267', 'Spermatogonia': '0.470', 'Spermatocytes': '-0.012', 'Early spermatids': '-0.469', 'Late spermatids': '-0.495', 'Oocytes': '5.9', 'Cytotrophoblasts': '4.3', 'Syncytiotrophoblasts': '2.5', 'Extravillous trophoblasts': '4.7', 'Endothelial cells': '24.5', 'Lymphatic endothelial cells': '10.0', 'Cardiomyocytes': '0.332', 'Skeletal myocytes': '0.594', 'Smooth muscle cells': '4.6', 'Adipocytes': '24.6', 'Melanocytes': '0.156', 'Fibroblasts': '5.0', 'Peritubular cells': '0.563', 'Endometrial stromal cells': '2.1', 'Ovarian stromal cells': '1.1', 'Undifferentiated cells': '11.5', 'T-cells': '5.6', 'B-cells': '14.2', 'Plasma cells': '3.8', 'Nk-cells': '3.0', 'Granulocytes': '28.5', 'Monocytes': '0.2', 'Macrophages': '3.1', 'Hofbauer cells': '3.8', 'Kupffer cells': '0.6', 'Dendritic cells': '0.4', 'Langerhans cells': '0.320', 'Erythroid cells': '-0.088', 'Adipocytes (Subcutaneous)': '-0.051', 'Adipocytes (Visceral)': '0.077', 'Breast glandular cells (progenitors)': '-0.004', 'Adipocytes (Breast)': '-0.098', 'Colon enterocytes': '0.174', 'Colon enteroendocrine cells': '0.058', 'Enteric glia cells': '0.256', 'Mitotic cells (Colon)': '0.261', 'Mitotic cells (Heart)': '0.388', 'Podocytes': '-0.180', 'Ascending Loop of Henle cells': '0.440', 'Intercalated cells': '-0.198', 'Cholangiocyte': '0.229', 'NK-cells (Liver)': '-0.157', 'Respiratory ciliated cells': '0.081', 'Mitotic cells (Lung)': '-0.135', 'NK-cells (Lung)': '0.541', 'B-cells (Lung)': '0.309', 'Alpha cells': '0.407', 'Beta cells': '0.237', 'Prostate glandular cells': '-0.291', 'Prostate basal glandular cells': '0.100', 'Urothelial cells': '0.296', 'Keratinocyte (other)': '0.642', 'Keratinocyte (granular)': '0.338', 'Hair cortex cells': '-0.410', 'Inner root sheath cells': '-0.355', 'Outer root sheath cells': '-0.300', 'Sebaceous gland cells': '-0.103', 'Eccrine sweat gland cells': '-0.510', 'Adipocytes (Skin)': '-0.465', 'Mitotic cells (Skin)': '0.135', 'Parietal cells': '-0.086', 'Chief cells': '-0.094', 'Gastric mucous cells': '0.430', 'Gastric enteroendocrine cells': '0.079', 'Mitotic cells (Stomach)': '0.463', 'Parafollicular cells': '0.059', 'Thyroid glandular cells': '0.072', 'Mitotic cells (Thyroid)': '0.134', 'Adrenal cortex cells': '0.224', 'Adrenal medulla cells': '0.058', 'Mitotic cells (Adrenal gland)': '0.216', 'Minor salivary glandular cells': '-0.055', 'Minor salivary gland ductal cells': '-0.206', 'Minor salivary gland basal cells': '0.479', 'Mitotic cells (Minor salivary gland)': '0.499', 'Adipocytes (Minor salivary gland)': '0.055', 'Somatotropes': '-0.380', 'Lactotropes': '-0.127', 'Gonadotropes': '0.199', 'Corticotropes': '-0.021', 'Thyrotropes': '0.282', 'Undifferentiated cells (Pituitary gland)': '0.361', 'Mitotic cells (Spleen)': '-0.105', 'Platelets': '-0.223', 'Erythrocytes': '-0.213', 'Hematopoietic stem cells': '-0.325', 'B-cells (Spleen)': '0.698', 'NK-cells (Spleen)': '0.315', 'Amygdala excitatory': '33.7', 'Cerebellar inhibitory': '25.5', 'Cge interneuron': '35.3', 'Deep-layer corticothalamic and 6b': '41.5', 'Deep-layer intratelencephalic': '27.0', 'Deep-layer near-projecting': '47.4', 'Eccentric medium spiny neuron': '36.8', 'Hippocampal ca1-3': '39.0', 'Hippocampal ca4': '26.4', 'Hippocampal dentate gyrus': '34.3', 'Lamp5-lhx6 and chandelier': '35.5', 'Lower rhombic lip': '10.9', 'Mammillary body': '38.2', 'Medium spiny neuron': '33.0', 'Mge interneuron': '33.8', 'Midbrain-derived inhibitory': '49.4', 'Miscellaneous': '34.3', 'Splatter': '28.3', 'Thalamic excitatory': '21.1', 'Upper rhombic lip': '17.8', 'Upper-layer intratelencephalic': '18.0', 'Astrocyte': '16.1', 'Bergmann glia': '97.5', 'Central nervous system macrophage': '61.6', 'Choroid plexus epithelial cell': '10.1', 'Committed oligodendrocyte precursor': '103.5', 'Ependymal cell': '17.9', 'Oligodendrocyte': '203.5', 'Oligodendrocyte precursor cell': '32.9', 'Endothelial cell': '118.2', 'Pericyte': '4.3', 'Vascular associated smooth muscle cell': '26.4', 'Fibroblast': '33.5', 'Leukocyte': '21.9', 'Basophil': '0.9', 'Eosinophil': '0.0', 'Neutrophil': '1.3', 'Classical monocyte': '1.5', 'Non-classical monocyte': '0.5', 'Intermediate monocyte': '0.3', 'T-reg': '5.0', 'GdT-cell': '0.2', 'MAIT T-cell': '7.3', 'Memory CD4 T-cell': '0.3', 'Naive CD4 T-cell': '22.0', 'Memory CD8 T-cell': '0.2', 'Naive CD8 T-cell': '20.4', 'Memory B-cell': '0.7', 'Naive B-cell': '146.3', 'Plasmacytoid DC': '2.7', 'Myeloid DC': '3.0', 'NK-cell': '14.0', 'Total PBMC': '3.6', 'Vd2 gdTCR': '6.2', 'Memory CD4 T-cell Th1\\/Th17': '33.6', 'Memory CD4 T-cell Th17': '34.8', 'Memory CD4 T-cell Th2': '36.4', 'Non-Vd2 gdTCR': '5.2', 'Memory CD4 T-cell Th1': '31.5', 'Memory CD4 T-cell TFH': '26.2', 'Terminal effector memory CD4 T-cell': '8.2', 'Central memory CD8 T-cell': '7.6', 'Effector memory CD8 T-cell': '4.5', 'Terminal effector memory CD8 T-cell': '3.7', 'Non-switched memory B-cell': '9.6', 'Plasmablast': '5.0', 'Switched memory B-cell': '12.0', 'Exhausted memory B-cell': '18.7', 'Progenitor cell': '6.5', 'Memory T-reg': '23.9', 'Naive CD4 T-cell activated': '13.5', 'Naive CD8 T-cell activated': '11.4', 'Naive T-reg': '13.8'} | null | {'Adipose Tissue': 13.92440531561462, 'Adrenal Gland': 4.136121317829458, 'Bladder': 15.531380952380951, 'Blood': 4.600168815931109, 'Blood Vessel': 10.632921348314609, 'Brain': 7.354622180166541, 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0.65, 0.06, 0.36, 0.66, 0.75, 0.73, 0.92, 0.93, 0.97, 1.0] | RING finger | Part of a complex consisting of TRIM27, USP7 and MAGEL2 | null | null | EID1, MAGED4, MAGEF1, SQSTM1, EPC1, CHD4, MAGEL2, PML, EIF3S6, PTPN11, USP7, | PIK3C2B, WASHC1, TBK1, NOD2,ULK1, STK38L | 48, 63 | null | null | Homomultimerizes | null | 88.603957 | 0.43115 | 74.343323 | 0.407644 | 153 |
P14373 | P38936 | 33251042 | UbiBrowser | TRIM27 | MASGSVAECLQQETTCPVCLQYFAEPMMLDCGHNICCACLARCWGTAETNVSCPQCRETFPQRHMRPNRHLANVTQLVKQLRTERPSGPGGEMGVCEKHREPLKLYCEEDQMPICVVCDRSREHRGHSVLPLEEAVEGFKEQIQNQLDHLKRVKDLKKRRRAQGEQARAELLSLTQMEREKIVWEFEQLYHSLKEHEYRLLARLEELDLAIYNSINGAITQFSCNISHLSSLIAQLEEKQQQPTRELLQDIGDTLSRAERIRIPEPWITPPDLQEKIHIFAQKCLFLTESLKQFTEKMQSDMEKIQELREAQLYSVDVTLDPDTAYPSLILSDNLRQVRYSYLQQDLPDNPERFNLFPCVLGSPCFIAGRHYWEVEVGDKAKWTIGVCEDSVCRKGGVTSAPQNGFWAVSLWYGKEYWALTSPMTALPLRTPLQRVGIFLDYDAGEVSFYNVTERCHTFTFSHATFCGPVRPYFSLSYSGGKSAAPLIICPMSGIDGFSGHVGNHGHSMETSP | Homo sapiens | Nucleus, Cytoplasm, Nucleus, PML body, Early endosome, Mitochondrion | Low tissue specificity | {'Ciliated cells': '25.1', 'Basal respiratory cells': '27.3', 'Club cells': '24.7', 'Ionocytes': '23.2', 'Mucus glandular cells': '21.7', 'Serous glandular cells': '33.5', 'Gastric mucus-secreting cells': '23.6', 'Proximal enterocytes': '20.1', 'Paneth cells': '20.0', 'Distal enterocytes': '15.1', 'Intestinal goblet cells': '37.0', 'Exocrine glandular cells': '-0.693', 'Basal prostatic cells': '43.6', 'Prostatic glandular cells': '43.5', 'Breast glandular cells': '0.696', 'Breast myoepithelial cells': '0.544', 'Glandular and luminal cells': '29.8', 'Secretory cells': '37.3', 'Basal keratinocytes': '26.5', 'Suprabasal keratinocytes': '15.7', 'Basal squamous epithelial cells': '34.1', 'Squamous epithelial cells': '21.9', 'Alveolar cells type 1': '-0.038', 'Alveolar cells type 2': '-0.408', 'Salivary duct cells': '18.1', 'Ductal cells': '0.480', 'Hepatocytes': '0.177', 'Cholangiocytes': '22.9', 'Proximal tubular cells': '0.232', 'Distal tubular cells': '18.4', 'Collecting duct cells': '27.2', 'Mesothelial cells': '0.392', 'Sertoli cells': '0.703', 'Granulosa cells': '19.2', 'Enteroendocrine cells': '31.0', 'Pancreatic endocrine cells': '18.7', 'Leydig cells': '0.636', 'Excitatory neurons': '13.0', 'Inhibitory neurons': '12.8', 'Cone photoreceptor cells': '13.6', 'Rod photoreceptor cells': '11.3', 'Bipolar cells': '10.1', 'Horizontal cells': '7.6', 'Astrocytes': '11.1', 'Oligodendrocyte precursor cells': '17.9', 'Oligodendrocytes': '18.4', 'Microglial cells': '16.1', 'Muller glia cells': '12.1', 'Schwann cells': '0.026', 'Spermatogonia': '0.420', 'Spermatocytes': '-0.042', 'Early spermatids': '-0.589', 'Late spermatids': '-0.706', 'Oocytes': '13.2', 'Cytotrophoblasts': '48.8', 'Syncytiotrophoblasts': '50.5', 'Extravillous trophoblasts': '58.8', 'Endothelial cells': '27.6', 'Lymphatic endothelial cells': '18.3', 'Cardiomyocytes': '0.444', 'Skeletal myocytes': '-0.371', 'Smooth muscle cells': '19.7', 'Adipocytes': '20.7', 'Melanocytes': '-0.177', 'Fibroblasts': '22.4', 'Peritubular cells': '0.559', 'Endometrial stromal cells': '27.3', 'Ovarian stromal cells': '24.5', 'Undifferentiated cells': '29.3', 'T-cells': '28.5', 'B-cells': '33.6', 'Plasma cells': '50.4', 'Nk-cells': '25.7', 'Granulocytes': '27.4', 'Monocytes': '32.5', 'Macrophages': '29.6', 'Hofbauer cells': '38.9', 'Kupffer cells': '31.1', 'Dendritic cells': '32.8', 'Langerhans cells': '0.075', 'Erythroid cells': '-0.057', 'Adipocytes (Subcutaneous)': '-0.199', 'Adipocytes (Visceral)': '-0.372', 'Breast glandular cells (progenitors)': '0.493', 'Adipocytes (Breast)': '-0.659', 'Colon enterocytes': '-0.039', 'Colon enteroendocrine cells': '0.155', 'Enteric glia cells': '0.411', 'Mitotic cells (Colon)': '0.069', 'Mitotic cells (Heart)': '0.481', 'Podocytes': '-0.080', 'Ascending Loop of Henle cells': '0.332', 'Intercalated cells': '-0.067', 'Cholangiocyte': '0.283', 'NK-cells (Liver)': '-0.293', 'Respiratory ciliated cells': '0.036', 'Mitotic cells (Lung)': '-0.109', 'NK-cells (Lung)': '0.295', 'B-cells (Lung)': '0.112', 'Alpha cells': '0.335', 'Beta cells': '0.170', 'Prostate glandular cells': '0.251', 'Prostate basal glandular cells': '0.383', 'Urothelial cells': '0.310', 'Keratinocyte (other)': '-0.109', 'Keratinocyte (granular)': '-0.354', 'Hair cortex cells': '0.029', 'Inner root sheath cells': '0.037', 'Outer root sheath cells': '0.284', 'Sebaceous gland cells': '0.136', 'Eccrine sweat gland cells': '0.208', 'Adipocytes (Skin)': '0.020', 'Mitotic cells (Skin)': '0.110', 'Parietal cells': '-0.236', 'Chief cells': '-0.025', 'Gastric mucous cells': '0.098', 'Gastric enteroendocrine cells': '0.091', 'Mitotic cells (Stomach)': '0.263', 'Parafollicular cells': '0.070', 'Thyroid glandular cells': '0.072', 'Mitotic cells (Thyroid)': '0.055', 'Adrenal cortex cells': '0.312', 'Adrenal medulla cells': '-0.104', 'Mitotic cells (Adrenal gland)': '-0.086', 'Minor salivary glandular cells': '0.517', 'Minor salivary gland ductal cells': '0.287', 'Minor salivary gland basal cells': '-0.017', 'Mitotic cells (Minor salivary gland)': '0.010', 'Adipocytes (Minor salivary gland)': '0.057', 'Somatotropes': '0.482', 'Lactotropes': '0.227', 'Gonadotropes': '0.066', 'Corticotropes': '0.019', 'Thyrotropes': '0.026', 'Undifferentiated cells (Pituitary gland)': '-0.250', 'Mitotic cells (Spleen)': '-0.238', 'Platelets': '-0.171', 'Erythrocytes': '-0.096', 'Hematopoietic stem cells': '-0.313', 'B-cells (Spleen)': '0.377', 'NK-cells (Spleen)': '0.278', 'Amygdala excitatory': '29.4', 'Cerebellar inhibitory': '15.3', 'Cge interneuron': '27.6', 'Deep-layer corticothalamic and 6b': '29.3', 'Deep-layer intratelencephalic': '31.8', 'Deep-layer near-projecting': '34.8', 'Eccentric medium spiny neuron': '27.3', 'Hippocampal ca1-3': '26.5', 'Hippocampal ca4': '28.4', 'Hippocampal dentate gyrus': '29.8', 'Lamp5-lhx6 and chandelier': '22.8', 'Lower rhombic lip': '32.2', 'Mammillary body': '18.8', 'Medium spiny neuron': '22.8', 'Mge interneuron': '26.6', 'Midbrain-derived inhibitory': '28.4', 'Miscellaneous': '30.0', 'Splatter': '27.8', 'Thalamic excitatory': '23.9', 'Upper rhombic lip': '24.1', 'Upper-layer intratelencephalic': '28.8', 'Astrocyte': '26.3', 'Bergmann glia': '25.2', 'Central nervous system macrophage': '78.3', 'Choroid plexus epithelial cell': '42.9', 'Committed oligodendrocyte precursor': '33.8', 'Ependymal cell': '20.3', 'Oligodendrocyte': '36.0', 'Oligodendrocyte precursor cell': '32.2', 'Endothelial cell': '58.5', 'Pericyte': '33.4', 'Vascular associated smooth muscle cell': '31.7', 'Fibroblast': '43.5', 'Leukocyte': '58.3', 'Basophil': '20.3', 'Eosinophil': '2.5', 'Neutrophil': '51.3', 'Classical monocyte': '17.4', 'Non-classical monocyte': '33.2', 'Intermediate monocyte': '36.3', 'T-reg': '19.6', 'GdT-cell': '7.2', 'MAIT T-cell': '29.7', 'Memory CD4 T-cell': '10.6', 'Naive CD4 T-cell': '29.7', 'Memory CD8 T-cell': '5.6', 'Naive CD8 T-cell': '28.3', 'Memory B-cell': '7.1', 'Naive B-cell': '18.7', 'Plasmacytoid DC': '27.3', 'Myeloid DC': '30.5', 'NK-cell': '26.2', 'Total PBMC': '23.0', 'Vd2 gdTCR': '19.2', 'Memory CD4 T-cell Th1\\/Th17': '22.6', 'Memory CD4 T-cell Th17': '23.3', 'Memory CD4 T-cell Th2': '23.3', 'Non-Vd2 gdTCR': '18.3', 'Memory CD4 T-cell Th1': '23.8', 'Memory CD4 T-cell TFH': '24.9', 'Terminal effector memory CD4 T-cell': '26.8', 'Central memory CD8 T-cell': '23.4', 'Effector memory CD8 T-cell': '21.7', 'Terminal effector memory CD8 T-cell': '14.3', 'Non-switched memory B-cell': '22.5', 'Plasmablast': '44.1', 'Switched memory B-cell': '25.7', 'Exhausted memory B-cell': '13.9', 'Progenitor cell': '20.6', 'Memory T-reg': '26.0', 'Naive CD4 T-cell activated': '55.5', 'Naive CD8 T-cell activated': '61.3', 'Naive T-reg': '32.5'} | null | {'Adipose Tissue': 30.51002491694352, 'Adrenal Gland': 28.42209302325581, 'Bladder': 42.15761904761904, 'Blood': 47.71387405812702, 'Blood Vessel': 35.17883895131086, 'Brain': 17.082769114307343, 'Breast': 35.04257080610022, 'Cervix Uteri': 56.090526315789475, 'Colon': 26.715078305519896, 'Esophagus': 25.588709342560552, 'Fallopian Tube': 54.83888888888889, 'Heart': 12.228174216027876, 'Kidney': 20.893404494382025, 'Liver': 28.784889380530977, 'Lung': 43.63569204152249, 'Muscle': 13.141891656288918, 'Nerve': 43.2170436187399, 'Ovary': 50.49094444444445, 'Pancreas': 26.43318292682927, 'Pituitary': 49.52038869257951, 'Prostate': 47.70363265306122, 'Salivary Gland': 32.1683950617284, 'Skin': 30.310514648977335, 'Small Intestine': 34.5279679144385, 'Spleen': 56.557759336099586, 'Stomach': 26.06833704735376, 'Testis': 26.19157894736842, 'Thyroid': 45.41816232771823, 'Uterus': 52.2319014084507, 'Vagina': 36.81769230769231} | CDKN1A | MSEPAGDVRQNPCGSKACRRLFGPVDSEQLSRDCDALMAGCIQEARERWNFDFVTETPLEGDFAWERVRGLGLPKLYLPTGPRRGRDELGGGRRPGTSPALLQGTAEEDHVDLSLSCTLVPRSGEQAEGSPGGPGDSQGRKRRQTSMTDFYHSKRRLIFSKRKP | Homo sapiens | Cytoplasm, Nucleus | Low tissue specificity | {'Ciliated cells': '219.2', 'Basal respiratory cells': '269.5', 'Club cells': '189.1', 'Ionocytes': '279.8', 'Mucus glandular cells': '202.6', 'Serous glandular cells': '151.8', 'Gastric mucus-secreting cells': '136.2', 'Proximal enterocytes': '345.5', 'Paneth cells': '170.9', 'Distal enterocytes': '374.3', 'Intestinal goblet cells': '199.6', 'Exocrine glandular cells': '-0.503', 'Basal prostatic cells': '263.3', 'Prostatic glandular cells': '36.9', 'Breast glandular cells': '-0.093', 'Breast myoepithelial cells': '0.013', 'Glandular and luminal cells': '205.8', 'Secretory cells': '211.3', 'Basal keratinocytes': '338.3', 'Suprabasal keratinocytes': '625.4', 'Basal squamous epithelial cells': '564.7', 'Squamous epithelial cells': '599.4', 'Alveolar cells type 1': '-0.006', 'Alveolar cells type 2': '-0.268', 'Salivary duct cells': '211.4', 'Ductal cells': '0.254', 'Hepatocytes': '-0.189', 'Cholangiocytes': '24.8', 'Proximal tubular cells': '0.179', 'Distal tubular cells': '43.0', 'Collecting duct cells': '77.8', 'Mesothelial cells': '-0.166', 'Sertoli cells': '0.547', 'Granulosa cells': '96.6', 'Enteroendocrine cells': '226.3', 'Pancreatic endocrine cells': '156.2', 'Leydig cells': '0.537', 'Excitatory neurons': '0.4', 'Inhibitory neurons': '0.4', 'Cone photoreceptor cells': '0.0', 'Rod photoreceptor cells': '0.8', 'Bipolar cells': '1.2', 'Horizontal cells': '1.3', 'Astrocytes': '0.9', 'Oligodendrocyte precursor cells': '0.0', 'Oligodendrocytes': '0.4', 'Microglial cells': '5.4', 'Muller glia cells': '67.7', 'Schwann cells': '-0.047', 'Spermatogonia': '0.312', 'Spermatocytes': '-0.173', 'Early spermatids': '-0.577', 'Late spermatids': '-0.573', 'Oocytes': '17.6', 'Cytotrophoblasts': '40.0', 'Syncytiotrophoblasts': '172.4', 'Extravillous trophoblasts': '57.7', 'Endothelial cells': '417.4', 'Lymphatic endothelial cells': '198.2', 'Cardiomyocytes': '0.152', 'Skeletal myocytes': '-0.199', 'Smooth muscle cells': '464.8', 'Adipocytes': '577.5', 'Melanocytes': '0.167', 'Fibroblasts': '258.4', 'Peritubular cells': '0.389', 'Endometrial stromal cells': '54.7', 'Ovarian stromal cells': '204.0', 'Undifferentiated cells': '43.2', 'T-cells': '98.5', 'B-cells': '134.5', 'Plasma cells': '326.2', 'Nk-cells': '26.2', 'Granulocytes': '246.5', 'Monocytes': '506.5', 'Macrophages': '288.1', 'Hofbauer cells': '139.3', 'Kupffer cells': '74.3', 'Dendritic cells': '95.0', 'Langerhans cells': '-0.032', 'Erythroid cells': '0.037', 'Adipocytes (Subcutaneous)': '-0.360', 'Adipocytes (Visceral)': '0.069', 'Breast glandular cells (progenitors)': '-0.168', 'Adipocytes (Breast)': '-0.071', 'Colon enterocytes': '-0.005', 'Colon enteroendocrine cells': '-0.041', 'Enteric glia cells': '-0.179', 'Mitotic cells (Colon)': '0.208', 'Mitotic cells (Heart)': '0.293', 'Podocytes': '0.152', 'Ascending Loop of Henle cells': '-0.065', 'Intercalated cells': '-0.145', 'Cholangiocyte': '0.343', 'NK-cells (Liver)': '-0.217', 'Respiratory ciliated cells': '-0.033', 'Mitotic cells (Lung)': '-0.190', 'NK-cells (Lung)': '0.157', 'B-cells (Lung)': '0.184', 'Alpha cells': '0.226', 'Beta cells': '0.160', 'Prostate glandular cells': '-0.244', 'Prostate basal glandular cells': '-0.132', 'Urothelial cells': '0.171', 'Keratinocyte (other)': '0.183', 'Keratinocyte (granular)': '-0.193', 'Hair cortex cells': '0.051', 'Inner root sheath cells': '0.111', 'Outer root sheath cells': '0.189', 'Sebaceous gland cells': '-0.160', 'Eccrine sweat gland cells': '-0.080', 'Adipocytes (Skin)': '-0.298', 'Mitotic cells (Skin)': '0.119', 'Parietal cells': '-0.445', 'Chief cells': '-0.447', 'Gastric mucous cells': '-0.250', 'Gastric enteroendocrine cells': '-0.355', 'Mitotic cells (Stomach)': '-0.063', 'Parafollicular cells': '-0.038', 'Thyroid glandular cells': '-0.105', 'Mitotic cells (Thyroid)': '0.052', 'Adrenal cortex cells': '0.188', 'Adrenal medulla cells': '0.047', 'Mitotic cells (Adrenal gland)': '-0.087', 'Minor salivary glandular cells': '0.239', 'Minor salivary gland ductal cells': '-0.263', 'Minor salivary gland basal cells': '0.564', 'Mitotic cells (Minor salivary gland)': '0.575', 'Adipocytes (Minor salivary gland)': '0.299', 'Somatotropes': '-0.188', 'Lactotropes': '-0.361', 'Gonadotropes': '-0.142', 'Corticotropes': '0.095', 'Thyrotropes': '-0.132', 'Undifferentiated cells (Pituitary gland)': '-0.032', 'Mitotic cells (Spleen)': '-0.164', 'Platelets': '-0.169', 'Erythrocytes': '-0.115', 'Hematopoietic stem cells': '-0.168', 'B-cells (Spleen)': '0.081', 'NK-cells (Spleen)': '-0.017', 'Amygdala excitatory': '0.8', 'Cerebellar inhibitory': '0.3', 'Cge interneuron': '0.4', 'Deep-layer corticothalamic and 6b': '1.0', 'Deep-layer intratelencephalic': '1.2', 'Deep-layer near-projecting': '0.2', 'Eccentric medium spiny neuron': '0.9', 'Hippocampal ca1-3': '0.4', 'Hippocampal ca4': '0.1', 'Hippocampal dentate gyrus': '0.3', 'Lamp5-lhx6 and chandelier': '0.1', 'Lower rhombic lip': '0.1', 'Mammillary body': '0.1', 'Medium spiny neuron': '0.8', 'Mge interneuron': '0.9', 'Midbrain-derived inhibitory': '0.1', 'Miscellaneous': '0.6', 'Splatter': '1.3', 'Thalamic excitatory': '0.3', 'Upper rhombic lip': '0.2', 'Upper-layer intratelencephalic': '1.0', 'Astrocyte': '3.7', 'Bergmann glia': '0.8', 'Central nervous system macrophage': '45.6', 'Choroid plexus epithelial cell': '57.6', 'Committed oligodendrocyte precursor': '1.5', 'Ependymal cell': '24.7', 'Oligodendrocyte': '0.2', 'Oligodendrocyte precursor cell': '0.7', 'Endothelial cell': '56.7', 'Pericyte': '8.8', 'Vascular associated smooth muscle cell': '46.9', 'Fibroblast': '10.3', 'Leukocyte': '8.0', 'Basophil': '2.2', 'Eosinophil': '0.5', 'Neutrophil': '7.6', 'Classical monocyte': '484.7', 'Non-classical monocyte': '172.5', 'Intermediate monocyte': '412.1', 'T-reg': '5.5', 'GdT-cell': '0.5', 'MAIT T-cell': '17.0', 'Memory CD4 T-cell': '1.1', 'Naive CD4 T-cell': '3.1', 'Memory CD8 T-cell': '0.6', 'Naive CD8 T-cell': '3.5', 'Memory B-cell': '20.8', 'Naive B-cell': '99.9', 'Plasmacytoid DC': '81.5', 'Myeloid DC': '344.0', 'NK-cell': '4.9', 'Total PBMC': '259.7', 'Vd2 gdTCR': '12.6', 'Memory CD4 T-cell Th1\\/Th17': '56.7', 'Memory CD4 T-cell Th17': '32.8', 'Memory CD4 T-cell Th2': '24.5', 'Non-Vd2 gdTCR': '14.0', 'Memory CD4 T-cell Th1': '42.0', 'Memory CD4 T-cell TFH': '12.6', 'Terminal effector memory CD4 T-cell': '5.2', 'Central memory CD8 T-cell': '4.1', 'Effector memory CD8 T-cell': '6.5', 'Terminal effector memory CD8 T-cell': '10.8', 'Non-switched memory B-cell': '126.9', 'Plasmablast': '79.6', 'Switched memory B-cell': '92.1', 'Exhausted memory B-cell': '109.4', 'Progenitor cell': '19.9', 'Memory T-reg': '14.0', 'Naive CD4 T-cell activated': '83.2', 'Naive CD8 T-cell activated': '40.7', 'Naive T-reg': '3.2'} | 1AXC, 2ZVV, 2ZVW, 4RJF, 5E0U, 6CBI, 6CEJ, 6CIV, 6CIX, 6P8H, 7KQ0, 7KQ1, 8GJF | {'Adipose Tissue': 298.2111129568106, 'Adrenal Gland': 93.4060465116279, 'Bladder': 197.83761904761903, 'Blood': 78.93353928955867, 'Blood Vessel': 448.1661423220974, 'Brain': 26.16142089326268, 'Breast': 190.7731372549019, 'Cervix Uteri': 154.54263157894738, 'Colon': 136.42021822849807, 'Esophagus': 163.55013148788927, 'Fallopian Tube': 361.2999999999999, 'Heart': 85.2329837398374, 'Kidney': 85.09125842696629, 'Liver': 87.66353539823008, 'Lung': 274.2942560553633, 'Muscle': 150.03065255292654, 'Nerve': 203.34387722132473, 'Ovary': 296.445, 'Pancreas': 57.98804878048781, 'Pituitary': 149.13120141342756, 'Prostate': 136.3737551020408, 'Salivary Gland': 92.8451172839506, 'Skin': 328.4404422332781, 'Small Intestine': 143.66491978609625, 'Spleen': 44.88352697095436, 'Stomach': 125.28008356545962, 'Testis': 83.37515235457064, 'Thyroid': 131.78820826952526, 'Uterus': 144.23007042253522, 'Vagina': 215.10339743589745} | [31.5, 48.3, 47.93, 54.46, 74.47, 78.85, 76.74, 76.48, 83.58, 84.99, 84.08, 86.19, 90.37, 91.51, 93.16, 94.46, 92.4, 92.37, 93.5, 90.87, 91.73, 91.32, 93.76, 91.13, 92.38, 94.72, 94.57, 95.42, 93.29, 91.17, 93.58, 92.64, 94.87, 95.5, 95.31, 95.76, 93.38, 92.94, 94.51, 91.84, 90.28, 90.83, 88.2, 90.02, 85.2, 83.0, 81.16, 78.84, 84.16, 85.85, 90.36, 91.7, 93.97, 91.39, 91.64, 93.8, 91.49, 92.75, 90.87, 87.99, 86.55, 85.4, 84.77, 85.3, 89.0, 93.28, 93.92, 95.14, 93.52, 93.54, 94.31, 92.24, 92.01, 92.08, 91.3, 87.38, 86.56, 86.67, 81.77, 74.78, 71.63, 63.07, 58.27, 39.95, 36.06, 36.86, 37.23, 30.59, 44.98, 38.69, 41.26, 46.45, 54.34, 72.04, 84.18, 86.24, 85.05, 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RING finger | Part of a complex consisting of TRIM27, USP7 and MAGEL2 | null | null | EID1, MAGED4, MAGEF1, SQSTM1, EPC1, CHD4, MAGEL2, PML, EIF3S6, PTPN11, USP7, | PIK3C2B, WASHC1, TBK1, NOD2,ULK1, STK38L | 48, 63 | null | null | Homomultimerizes | null | 88.603957 | 0.43115 | 68.75 | 0.766829 | 2,849 |
P14373 | P60484 | 31719796 | UbiBrowser | TRIM27 | MASGSVAECLQQETTCPVCLQYFAEPMMLDCGHNICCACLARCWGTAETNVSCPQCRETFPQRHMRPNRHLANVTQLVKQLRTERPSGPGGEMGVCEKHREPLKLYCEEDQMPICVVCDRSREHRGHSVLPLEEAVEGFKEQIQNQLDHLKRVKDLKKRRRAQGEQARAELLSLTQMEREKIVWEFEQLYHSLKEHEYRLLARLEELDLAIYNSINGAITQFSCNISHLSSLIAQLEEKQQQPTRELLQDIGDTLSRAERIRIPEPWITPPDLQEKIHIFAQKCLFLTESLKQFTEKMQSDMEKIQELREAQLYSVDVTLDPDTAYPSLILSDNLRQVRYSYLQQDLPDNPERFNLFPCVLGSPCFIAGRHYWEVEVGDKAKWTIGVCEDSVCRKGGVTSAPQNGFWAVSLWYGKEYWALTSPMTALPLRTPLQRVGIFLDYDAGEVSFYNVTERCHTFTFSHATFCGPVRPYFSLSYSGGKSAAPLIICPMSGIDGFSGHVGNHGHSMETSP | Homo sapiens | Nucleus, Cytoplasm, Nucleus, PML body, Early endosome, Mitochondrion | Low tissue specificity | {'Ciliated cells': '25.1', 'Basal respiratory cells': '27.3', 'Club cells': '24.7', 'Ionocytes': '23.2', 'Mucus glandular cells': '21.7', 'Serous glandular cells': '33.5', 'Gastric mucus-secreting cells': '23.6', 'Proximal enterocytes': '20.1', 'Paneth cells': '20.0', 'Distal enterocytes': '15.1', 'Intestinal goblet cells': '37.0', 'Exocrine glandular cells': '-0.693', 'Basal prostatic cells': '43.6', 'Prostatic glandular cells': '43.5', 'Breast glandular cells': '0.696', 'Breast myoepithelial cells': '0.544', 'Glandular and luminal cells': '29.8', 'Secretory cells': '37.3', 'Basal keratinocytes': '26.5', 'Suprabasal keratinocytes': '15.7', 'Basal squamous epithelial cells': '34.1', 'Squamous epithelial cells': '21.9', 'Alveolar cells type 1': '-0.038', 'Alveolar cells type 2': '-0.408', 'Salivary duct cells': '18.1', 'Ductal cells': '0.480', 'Hepatocytes': '0.177', 'Cholangiocytes': '22.9', 'Proximal tubular cells': '0.232', 'Distal tubular cells': '18.4', 'Collecting duct cells': '27.2', 'Mesothelial cells': '0.392', 'Sertoli cells': '0.703', 'Granulosa cells': '19.2', 'Enteroendocrine cells': '31.0', 'Pancreatic endocrine cells': '18.7', 'Leydig cells': '0.636', 'Excitatory neurons': '13.0', 'Inhibitory neurons': '12.8', 'Cone photoreceptor cells': '13.6', 'Rod photoreceptor cells': '11.3', 'Bipolar cells': '10.1', 'Horizontal cells': '7.6', 'Astrocytes': '11.1', 'Oligodendrocyte precursor cells': '17.9', 'Oligodendrocytes': '18.4', 'Microglial cells': '16.1', 'Muller glia cells': '12.1', 'Schwann cells': '0.026', 'Spermatogonia': '0.420', 'Spermatocytes': '-0.042', 'Early spermatids': '-0.589', 'Late spermatids': '-0.706', 'Oocytes': '13.2', 'Cytotrophoblasts': '48.8', 'Syncytiotrophoblasts': '50.5', 'Extravillous trophoblasts': '58.8', 'Endothelial cells': '27.6', 'Lymphatic endothelial cells': '18.3', 'Cardiomyocytes': '0.444', 'Skeletal myocytes': '-0.371', 'Smooth muscle cells': '19.7', 'Adipocytes': '20.7', 'Melanocytes': '-0.177', 'Fibroblasts': '22.4', 'Peritubular cells': '0.559', 'Endometrial stromal cells': '27.3', 'Ovarian stromal cells': '24.5', 'Undifferentiated cells': '29.3', 'T-cells': '28.5', 'B-cells': '33.6', 'Plasma cells': '50.4', 'Nk-cells': '25.7', 'Granulocytes': '27.4', 'Monocytes': '32.5', 'Macrophages': '29.6', 'Hofbauer cells': '38.9', 'Kupffer cells': '31.1', 'Dendritic cells': '32.8', 'Langerhans cells': '0.075', 'Erythroid cells': '-0.057', 'Adipocytes (Subcutaneous)': '-0.199', 'Adipocytes (Visceral)': '-0.372', 'Breast glandular cells (progenitors)': '0.493', 'Adipocytes (Breast)': '-0.659', 'Colon enterocytes': '-0.039', 'Colon enteroendocrine cells': '0.155', 'Enteric glia cells': '0.411', 'Mitotic cells (Colon)': '0.069', 'Mitotic cells (Heart)': '0.481', 'Podocytes': '-0.080', 'Ascending Loop of Henle cells': '0.332', 'Intercalated cells': '-0.067', 'Cholangiocyte': '0.283', 'NK-cells (Liver)': '-0.293', 'Respiratory ciliated cells': '0.036', 'Mitotic cells (Lung)': '-0.109', 'NK-cells (Lung)': '0.295', 'B-cells (Lung)': '0.112', 'Alpha cells': '0.335', 'Beta cells': '0.170', 'Prostate glandular cells': '0.251', 'Prostate basal glandular cells': '0.383', 'Urothelial cells': '0.310', 'Keratinocyte (other)': '-0.109', 'Keratinocyte (granular)': '-0.354', 'Hair cortex cells': '0.029', 'Inner root sheath cells': '0.037', 'Outer root sheath cells': '0.284', 'Sebaceous gland cells': '0.136', 'Eccrine sweat gland cells': '0.208', 'Adipocytes (Skin)': '0.020', 'Mitotic cells (Skin)': '0.110', 'Parietal cells': '-0.236', 'Chief cells': '-0.025', 'Gastric mucous cells': '0.098', 'Gastric enteroendocrine cells': '0.091', 'Mitotic cells (Stomach)': '0.263', 'Parafollicular cells': '0.070', 'Thyroid glandular cells': '0.072', 'Mitotic cells (Thyroid)': '0.055', 'Adrenal cortex cells': '0.312', 'Adrenal medulla cells': '-0.104', 'Mitotic cells (Adrenal gland)': '-0.086', 'Minor salivary glandular cells': '0.517', 'Minor salivary gland ductal cells': '0.287', 'Minor salivary gland basal cells': '-0.017', 'Mitotic cells (Minor salivary gland)': '0.010', 'Adipocytes (Minor salivary gland)': '0.057', 'Somatotropes': '0.482', 'Lactotropes': '0.227', 'Gonadotropes': '0.066', 'Corticotropes': '0.019', 'Thyrotropes': '0.026', 'Undifferentiated cells (Pituitary gland)': '-0.250', 'Mitotic cells (Spleen)': '-0.238', 'Platelets': '-0.171', 'Erythrocytes': '-0.096', 'Hematopoietic stem cells': '-0.313', 'B-cells (Spleen)': '0.377', 'NK-cells (Spleen)': '0.278', 'Amygdala excitatory': '29.4', 'Cerebellar inhibitory': '15.3', 'Cge interneuron': '27.6', 'Deep-layer corticothalamic and 6b': '29.3', 'Deep-layer intratelencephalic': '31.8', 'Deep-layer near-projecting': '34.8', 'Eccentric medium spiny neuron': '27.3', 'Hippocampal ca1-3': '26.5', 'Hippocampal ca4': '28.4', 'Hippocampal dentate gyrus': '29.8', 'Lamp5-lhx6 and chandelier': '22.8', 'Lower rhombic lip': '32.2', 'Mammillary body': '18.8', 'Medium spiny neuron': '22.8', 'Mge interneuron': '26.6', 'Midbrain-derived inhibitory': '28.4', 'Miscellaneous': '30.0', 'Splatter': '27.8', 'Thalamic excitatory': '23.9', 'Upper rhombic lip': '24.1', 'Upper-layer intratelencephalic': '28.8', 'Astrocyte': '26.3', 'Bergmann glia': '25.2', 'Central nervous system macrophage': '78.3', 'Choroid plexus epithelial cell': '42.9', 'Committed oligodendrocyte precursor': '33.8', 'Ependymal cell': '20.3', 'Oligodendrocyte': '36.0', 'Oligodendrocyte precursor cell': '32.2', 'Endothelial cell': '58.5', 'Pericyte': '33.4', 'Vascular associated smooth muscle cell': '31.7', 'Fibroblast': '43.5', 'Leukocyte': '58.3', 'Basophil': '20.3', 'Eosinophil': '2.5', 'Neutrophil': '51.3', 'Classical monocyte': '17.4', 'Non-classical monocyte': '33.2', 'Intermediate monocyte': '36.3', 'T-reg': '19.6', 'GdT-cell': '7.2', 'MAIT T-cell': '29.7', 'Memory CD4 T-cell': '10.6', 'Naive CD4 T-cell': '29.7', 'Memory CD8 T-cell': '5.6', 'Naive CD8 T-cell': '28.3', 'Memory B-cell': '7.1', 'Naive B-cell': '18.7', 'Plasmacytoid DC': '27.3', 'Myeloid DC': '30.5', 'NK-cell': '26.2', 'Total PBMC': '23.0', 'Vd2 gdTCR': '19.2', 'Memory CD4 T-cell Th1\\/Th17': '22.6', 'Memory CD4 T-cell Th17': '23.3', 'Memory CD4 T-cell Th2': '23.3', 'Non-Vd2 gdTCR': '18.3', 'Memory CD4 T-cell Th1': '23.8', 'Memory CD4 T-cell TFH': '24.9', 'Terminal effector memory CD4 T-cell': '26.8', 'Central memory CD8 T-cell': '23.4', 'Effector memory CD8 T-cell': '21.7', 'Terminal effector memory CD8 T-cell': '14.3', 'Non-switched memory B-cell': '22.5', 'Plasmablast': '44.1', 'Switched memory B-cell': '25.7', 'Exhausted memory B-cell': '13.9', 'Progenitor cell': '20.6', 'Memory T-reg': '26.0', 'Naive CD4 T-cell activated': '55.5', 'Naive CD8 T-cell activated': '61.3', 'Naive T-reg': '32.5'} | null | {'Adipose Tissue': 30.51002491694352, 'Adrenal Gland': 28.42209302325581, 'Bladder': 42.15761904761904, 'Blood': 47.71387405812702, 'Blood Vessel': 35.17883895131086, 'Brain': 17.082769114307343, 'Breast': 35.04257080610022, 'Cervix Uteri': 56.090526315789475, 'Colon': 26.715078305519896, 'Esophagus': 25.588709342560552, 'Fallopian Tube': 54.83888888888889, 'Heart': 12.228174216027876, 'Kidney': 20.893404494382025, 'Liver': 28.784889380530977, 'Lung': 43.63569204152249, 'Muscle': 13.141891656288918, 'Nerve': 43.2170436187399, 'Ovary': 50.49094444444445, 'Pancreas': 26.43318292682927, 'Pituitary': 49.52038869257951, 'Prostate': 47.70363265306122, 'Salivary Gland': 32.1683950617284, 'Skin': 30.310514648977335, 'Small Intestine': 34.5279679144385, 'Spleen': 56.557759336099586, 'Stomach': 26.06833704735376, 'Testis': 26.19157894736842, 'Thyroid': 45.41816232771823, 'Uterus': 52.2319014084507, 'Vagina': 36.81769230769231} | PTEN | MTAIIKEIVSRNKRRYQEDGFDLDLTYIYPNIIAMGFPAERLEGVYRNNIDDVVRFLDSKHKNHYKIYNLCAERHYDTAKFNCRVAQYPFEDHNPPQLELIKPFCEDLDQWLSEDDNHVAAIHCKAGKGRTGVMICAYLLHRGKFLKAQEALDFYGEVRTRDKKGVTIPSQRRYVYYYSYLLKNHLDYRPVALLFHKMMFETIPMFSGGTCNPQFVVCQLKVKIYSSNSGPTRREDKFMYFEFPQPLPVCGDIKVEFFHKQNKMLKKDKMFHFWVNTFFIPGPEETSEKVENGSLCDQEIDSICSIERADNDKEYLVLTLTKNDLDKANKDKANRYFSPNFKVKLYFTKTVEEPSNPEASSSTSVTPDVSDNEPDHYRYSDTTDSDPENEPFDEDQHTQITKV | Homo sapiens | Cytoplasm, Nucleus, Nucleus, PML body, Cell projection, dendritic spine, Postsynaptic density, Secreted | Low tissue specificity | {'Ciliated cells': '34.7', 'Basal respiratory cells': '24.4', 'Club cells': '41.2', 'Ionocytes': '19.5', 'Mucus glandular cells': '31.9', 'Serous glandular cells': '53.3', 'Gastric mucus-secreting cells': '39.5', 'Proximal enterocytes': '40.3', 'Paneth cells': '37.7', 'Distal enterocytes': '54.6', 'Intestinal goblet cells': '46.7', 'Exocrine glandular cells': '-0.548', 'Basal prostatic cells': '44.4', 'Prostatic glandular cells': '36.1', 'Breast glandular cells': '-0.229', 'Breast myoepithelial cells': '-0.337', 'Glandular and luminal cells': '27.5', 'Secretory cells': '50.5', 'Basal keratinocytes': '45.9', 'Suprabasal keratinocytes': '50.4', 'Basal squamous epithelial cells': '45.7', 'Squamous epithelial cells': '42.3', 'Alveolar cells type 1': '0.015', 'Alveolar cells type 2': '-0.333', 'Salivary duct cells': '32.9', 'Ductal cells': '0.522', 'Hepatocytes': '0.237', 'Cholangiocytes': '45.8', 'Proximal tubular cells': '0.169', 'Distal tubular cells': '15.4', 'Collecting duct cells': '27.2', 'Mesothelial cells': '-0.026', 'Sertoli cells': '-0.192', 'Granulosa cells': '22.8', 'Enteroendocrine cells': '28.0', 'Pancreatic endocrine cells': '11.9', 'Leydig cells': '-0.043', 'Excitatory neurons': '136.2', 'Inhibitory neurons': '126.7', 'Cone photoreceptor cells': '22.1', 'Rod photoreceptor cells': '54.9', 'Bipolar cells': '84.0', 'Horizontal cells': '47.8', 'Astrocytes': '79.3', 'Oligodendrocyte precursor cells': '130.6', 'Oligodendrocytes': '89.1', 'Microglial cells': '187.9', 'Muller glia cells': '55.2', 'Schwann cells': '0.259', 'Spermatogonia': '0.079', 'Spermatocytes': '0.281', 'Early spermatids': '0.555', 'Late spermatids': '0.136', 'Oocytes': '18.4', 'Cytotrophoblasts': '17.7', 'Syncytiotrophoblasts': '34.4', 'Extravillous trophoblasts': '35.3', 'Endothelial cells': '40.5', 'Lymphatic endothelial cells': '33.6', 'Cardiomyocytes': '0.544', 'Skeletal myocytes': '-0.216', 'Smooth muscle cells': '135.5', 'Adipocytes': '52.5', 'Melanocytes': '0.017', 'Fibroblasts': '90.5', 'Peritubular cells': '0.110', 'Endometrial stromal cells': '95.1', 'Ovarian stromal cells': '33.0', 'Undifferentiated cells': '38.2', 'T-cells': '42.8', 'B-cells': '52.5', 'Plasma cells': '34.4', 'Nk-cells': '44.4', 'Granulocytes': '40.8', 'Monocytes': '216.4', 'Macrophages': '97.1', 'Hofbauer cells': '35.4', 'Kupffer cells': '160.0', 'Dendritic cells': '62.0', 'Langerhans cells': '0.062', 'Erythroid cells': '0.155', 'Adipocytes (Subcutaneous)': '0.348', 'Adipocytes (Visceral)': '0.287', 'Breast glandular cells (progenitors)': '-0.197', 'Adipocytes (Breast)': '0.582', 'Colon enterocytes': '-0.162', 'Colon enteroendocrine cells': '0.365', 'Enteric glia cells': '0.405', 'Mitotic cells (Colon)': '-0.024', 'Mitotic cells (Heart)': '0.534', 'Podocytes': '0.017', 'Ascending Loop of Henle cells': '0.411', 'Intercalated cells': '-0.005', 'Cholangiocyte': '0.283', 'NK-cells (Liver)': '-0.021', 'Respiratory ciliated cells': '-0.001', 'Mitotic cells (Lung)': '-0.068', 'NK-cells (Lung)': '0.106', 'B-cells (Lung)': '0.077', 'Alpha cells': '0.447', 'Beta cells': '0.268', 'Prostate glandular cells': '-0.492', 'Prostate basal glandular cells': '-0.150', 'Urothelial cells': '0.050', 'Keratinocyte (other)': '-0.123', 'Keratinocyte (granular)': '-0.213', 'Hair cortex cells': '0.026', 'Inner root sheath cells': '0.141', 'Outer root sheath cells': '0.232', 'Sebaceous gland cells': '0.175', 'Eccrine sweat gland cells': '0.150', 'Adipocytes (Skin)': '0.226', 'Mitotic cells (Skin)': '0.233', 'Parietal cells': '-0.626', 'Chief cells': '-0.457', 'Gastric mucous cells': '-0.513', 'Gastric enteroendocrine cells': '-0.328', 'Mitotic cells (Stomach)': '-0.071', 'Parafollicular cells': '0.026', 'Thyroid glandular cells': '0.255', 'Mitotic cells (Thyroid)': '0.080', 'Adrenal cortex cells': '0.466', 'Adrenal medulla cells': '0.137', 'Mitotic cells (Adrenal gland)': '0.369', 'Minor salivary glandular cells': '0.369', 'Minor salivary gland ductal cells': '0.083', 'Minor salivary gland basal cells': '0.484', 'Mitotic cells (Minor salivary gland)': '0.482', 'Adipocytes (Minor salivary gland)': '0.435', 'Somatotropes': '-0.164', 'Lactotropes': '-0.103', 'Gonadotropes': '-0.079', 'Corticotropes': '-0.068', 'Thyrotropes': '0.126', 'Undifferentiated cells (Pituitary gland)': '0.285', 'Mitotic cells (Spleen)': '-0.350', 'Platelets': '0.006', 'Erythrocytes': '-0.209', 'Hematopoietic stem cells': '-0.101', 'B-cells (Spleen)': '0.186', 'NK-cells (Spleen)': '0.234', 'Amygdala excitatory': '205.9', 'Cerebellar inhibitory': '243.7', 'Cge interneuron': '187.7', 'Deep-layer corticothalamic and 6b': '208.3', 'Deep-layer intratelencephalic': '187.6', 'Deep-layer near-projecting': '204.7', 'Eccentric medium spiny neuron': '242.6', 'Hippocampal ca1-3': '187.3', 'Hippocampal ca4': '167.1', 'Hippocampal dentate gyrus': '185.4', 'Lamp5-lhx6 and chandelier': '218.8', 'Lower rhombic lip': '174.1', 'Mammillary body': '217.2', 'Medium spiny neuron': '189.9', 'Mge interneuron': '159.6', 'Midbrain-derived inhibitory': '240.2', 'Miscellaneous': '218.2', 'Splatter': 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P14373 | Q15561 | 33993634 | UbiBrowser | TRIM27 | MASGSVAECLQQETTCPVCLQYFAEPMMLDCGHNICCACLARCWGTAETNVSCPQCRETFPQRHMRPNRHLANVTQLVKQLRTERPSGPGGEMGVCEKHREPLKLYCEEDQMPICVVCDRSREHRGHSVLPLEEAVEGFKEQIQNQLDHLKRVKDLKKRRRAQGEQARAELLSLTQMEREKIVWEFEQLYHSLKEHEYRLLARLEELDLAIYNSINGAITQFSCNISHLSSLIAQLEEKQQQPTRELLQDIGDTLSRAERIRIPEPWITPPDLQEKIHIFAQKCLFLTESLKQFTEKMQSDMEKIQELREAQLYSVDVTLDPDTAYPSLILSDNLRQVRYSYLQQDLPDNPERFNLFPCVLGSPCFIAGRHYWEVEVGDKAKWTIGVCEDSVCRKGGVTSAPQNGFWAVSLWYGKEYWALTSPMTALPLRTPLQRVGIFLDYDAGEVSFYNVTERCHTFTFSHATFCGPVRPYFSLSYSGGKSAAPLIICPMSGIDGFSGHVGNHGHSMETSP | Homo sapiens | Nucleus, Cytoplasm, Nucleus, PML body, Early endosome, Mitochondrion | Low tissue specificity | {'Ciliated cells': '25.1', 'Basal respiratory cells': '27.3', 'Club cells': '24.7', 'Ionocytes': '23.2', 'Mucus glandular cells': '21.7', 'Serous glandular cells': '33.5', 'Gastric mucus-secreting cells': '23.6', 'Proximal enterocytes': '20.1', 'Paneth cells': '20.0', 'Distal enterocytes': '15.1', 'Intestinal goblet cells': '37.0', 'Exocrine glandular cells': '-0.693', 'Basal prostatic cells': '43.6', 'Prostatic glandular cells': '43.5', 'Breast glandular cells': '0.696', 'Breast myoepithelial cells': '0.544', 'Glandular and luminal cells': '29.8', 'Secretory cells': '37.3', 'Basal keratinocytes': '26.5', 'Suprabasal keratinocytes': '15.7', 'Basal squamous epithelial cells': '34.1', 'Squamous epithelial cells': '21.9', 'Alveolar cells type 1': '-0.038', 'Alveolar cells type 2': '-0.408', 'Salivary duct cells': '18.1', 'Ductal cells': '0.480', 'Hepatocytes': '0.177', 'Cholangiocytes': '22.9', 'Proximal tubular cells': '0.232', 'Distal tubular cells': '18.4', 'Collecting duct cells': '27.2', 'Mesothelial cells': '0.392', 'Sertoli cells': '0.703', 'Granulosa cells': '19.2', 'Enteroendocrine cells': '31.0', 'Pancreatic endocrine cells': '18.7', 'Leydig cells': '0.636', 'Excitatory neurons': '13.0', 'Inhibitory neurons': '12.8', 'Cone photoreceptor cells': '13.6', 'Rod photoreceptor cells': '11.3', 'Bipolar cells': '10.1', 'Horizontal cells': '7.6', 'Astrocytes': '11.1', 'Oligodendrocyte precursor cells': '17.9', 'Oligodendrocytes': '18.4', 'Microglial cells': '16.1', 'Muller glia cells': '12.1', 'Schwann cells': '0.026', 'Spermatogonia': '0.420', 'Spermatocytes': '-0.042', 'Early spermatids': '-0.589', 'Late spermatids': '-0.706', 'Oocytes': '13.2', 'Cytotrophoblasts': '48.8', 'Syncytiotrophoblasts': '50.5', 'Extravillous trophoblasts': '58.8', 'Endothelial cells': '27.6', 'Lymphatic endothelial cells': '18.3', 'Cardiomyocytes': '0.444', 'Skeletal myocytes': '-0.371', 'Smooth muscle cells': '19.7', 'Adipocytes': '20.7', 'Melanocytes': '-0.177', 'Fibroblasts': '22.4', 'Peritubular cells': '0.559', 'Endometrial stromal cells': '27.3', 'Ovarian stromal cells': '24.5', 'Undifferentiated cells': '29.3', 'T-cells': '28.5', 'B-cells': '33.6', 'Plasma cells': '50.4', 'Nk-cells': '25.7', 'Granulocytes': '27.4', 'Monocytes': '32.5', 'Macrophages': '29.6', 'Hofbauer cells': '38.9', 'Kupffer cells': '31.1', 'Dendritic cells': '32.8', 'Langerhans cells': '0.075', 'Erythroid cells': '-0.057', 'Adipocytes (Subcutaneous)': '-0.199', 'Adipocytes (Visceral)': '-0.372', 'Breast glandular cells (progenitors)': '0.493', 'Adipocytes (Breast)': '-0.659', 'Colon enterocytes': '-0.039', 'Colon enteroendocrine cells': '0.155', 'Enteric glia cells': '0.411', 'Mitotic cells (Colon)': '0.069', 'Mitotic cells (Heart)': '0.481', 'Podocytes': '-0.080', 'Ascending Loop of Henle cells': '0.332', 'Intercalated cells': '-0.067', 'Cholangiocyte': '0.283', 'NK-cells (Liver)': '-0.293', 'Respiratory ciliated cells': '0.036', 'Mitotic cells (Lung)': '-0.109', 'NK-cells (Lung)': '0.295', 'B-cells (Lung)': '0.112', 'Alpha cells': '0.335', 'Beta cells': '0.170', 'Prostate glandular cells': '0.251', 'Prostate basal glandular cells': '0.383', 'Urothelial cells': '0.310', 'Keratinocyte (other)': '-0.109', 'Keratinocyte (granular)': '-0.354', 'Hair cortex cells': '0.029', 'Inner root sheath cells': '0.037', 'Outer root sheath cells': '0.284', 'Sebaceous gland cells': '0.136', 'Eccrine sweat gland cells': '0.208', 'Adipocytes (Skin)': '0.020', 'Mitotic cells (Skin)': '0.110', 'Parietal cells': '-0.236', 'Chief cells': '-0.025', 'Gastric mucous cells': '0.098', 'Gastric enteroendocrine cells': '0.091', 'Mitotic cells (Stomach)': '0.263', 'Parafollicular cells': '0.070', 'Thyroid glandular cells': '0.072', 'Mitotic cells (Thyroid)': '0.055', 'Adrenal cortex cells': '0.312', 'Adrenal medulla cells': '-0.104', 'Mitotic cells (Adrenal gland)': '-0.086', 'Minor salivary glandular cells': '0.517', 'Minor salivary gland ductal cells': '0.287', 'Minor salivary gland basal cells': '-0.017', 'Mitotic cells (Minor salivary gland)': '0.010', 'Adipocytes (Minor salivary gland)': '0.057', 'Somatotropes': '0.482', 'Lactotropes': '0.227', 'Gonadotropes': '0.066', 'Corticotropes': '0.019', 'Thyrotropes': '0.026', 'Undifferentiated cells (Pituitary gland)': '-0.250', 'Mitotic cells (Spleen)': '-0.238', 'Platelets': '-0.171', 'Erythrocytes': '-0.096', 'Hematopoietic stem cells': '-0.313', 'B-cells (Spleen)': '0.377', 'NK-cells (Spleen)': '0.278', 'Amygdala excitatory': '29.4', 'Cerebellar inhibitory': '15.3', 'Cge interneuron': '27.6', 'Deep-layer corticothalamic and 6b': '29.3', 'Deep-layer intratelencephalic': '31.8', 'Deep-layer near-projecting': '34.8', 'Eccentric medium spiny neuron': '27.3', 'Hippocampal ca1-3': '26.5', 'Hippocampal ca4': '28.4', 'Hippocampal dentate gyrus': '29.8', 'Lamp5-lhx6 and chandelier': '22.8', 'Lower rhombic lip': '32.2', 'Mammillary body': '18.8', 'Medium spiny neuron': '22.8', 'Mge interneuron': '26.6', 'Midbrain-derived inhibitory': '28.4', 'Miscellaneous': '30.0', 'Splatter': '27.8', 'Thalamic excitatory': '23.9', 'Upper rhombic lip': '24.1', 'Upper-layer intratelencephalic': '28.8', 'Astrocyte': '26.3', 'Bergmann glia': '25.2', 'Central nervous system macrophage': '78.3', 'Choroid plexus epithelial cell': '42.9', 'Committed oligodendrocyte precursor': '33.8', 'Ependymal cell': '20.3', 'Oligodendrocyte': '36.0', 'Oligodendrocyte precursor cell': '32.2', 'Endothelial cell': '58.5', 'Pericyte': '33.4', 'Vascular associated smooth muscle cell': '31.7', 'Fibroblast': '43.5', 'Leukocyte': '58.3', 'Basophil': '20.3', 'Eosinophil': '2.5', 'Neutrophil': '51.3', 'Classical monocyte': '17.4', 'Non-classical monocyte': '33.2', 'Intermediate monocyte': '36.3', 'T-reg': '19.6', 'GdT-cell': '7.2', 'MAIT T-cell': '29.7', 'Memory CD4 T-cell': '10.6', 'Naive CD4 T-cell': '29.7', 'Memory CD8 T-cell': '5.6', 'Naive CD8 T-cell': '28.3', 'Memory B-cell': '7.1', 'Naive B-cell': '18.7', 'Plasmacytoid DC': '27.3', 'Myeloid DC': '30.5', 'NK-cell': '26.2', 'Total PBMC': '23.0', 'Vd2 gdTCR': '19.2', 'Memory CD4 T-cell Th1\\/Th17': '22.6', 'Memory CD4 T-cell Th17': '23.3', 'Memory CD4 T-cell Th2': '23.3', 'Non-Vd2 gdTCR': '18.3', 'Memory CD4 T-cell Th1': '23.8', 'Memory CD4 T-cell TFH': '24.9', 'Terminal effector memory CD4 T-cell': '26.8', 'Central memory CD8 T-cell': '23.4', 'Effector memory CD8 T-cell': '21.7', 'Terminal effector memory CD8 T-cell': '14.3', 'Non-switched memory B-cell': '22.5', 'Plasmablast': '44.1', 'Switched memory B-cell': '25.7', 'Exhausted memory B-cell': '13.9', 'Progenitor cell': '20.6', 'Memory T-reg': '26.0', 'Naive CD4 T-cell activated': '55.5', 'Naive CD8 T-cell activated': '61.3', 'Naive T-reg': '32.5'} | null | {'Adipose Tissue': 30.51002491694352, 'Adrenal Gland': 28.42209302325581, 'Bladder': 42.15761904761904, 'Blood': 47.71387405812702, 'Blood Vessel': 35.17883895131086, 'Brain': 17.082769114307343, 'Breast': 35.04257080610022, 'Cervix Uteri': 56.090526315789475, 'Colon': 26.715078305519896, 'Esophagus': 25.588709342560552, 'Fallopian Tube': 54.83888888888889, 'Heart': 12.228174216027876, 'Kidney': 20.893404494382025, 'Liver': 28.784889380530977, 'Lung': 43.63569204152249, 'Muscle': 13.141891656288918, 'Nerve': 43.2170436187399, 'Ovary': 50.49094444444445, 'Pancreas': 26.43318292682927, 'Pituitary': 49.52038869257951, 'Prostate': 47.70363265306122, 'Salivary Gland': 32.1683950617284, 'Skin': 30.310514648977335, 'Small Intestine': 34.5279679144385, 'Spleen': 56.557759336099586, 'Stomach': 26.06833704735376, 'Testis': 26.19157894736842, 'Thyroid': 45.41816232771823, 'Uterus': 52.2319014084507, 'Vagina': 36.81769230769231} | TEAD4 | MEGTAGTITSNEWSSPTSPEGSTASGGSQALDKPIDNDAEGVWSPDIEQSFQEALAIYPPCGRRKIILSDEGKMYGRNELIARYIKLRTGKTRTRKQVSSHIQVLARRKAREIQAKLKDQAAKDKALQSMAAMSSAQIISATAFHSSMALARGPGRPAVSGFWQGALPGQAGTSHDVKPFSQQTYAVQPPLPLPGFESPAGPAPSPSAPPAPPWQGRSVASSKLWMLEFSAFLEQQQDPDTYNKHLFVHIGQSSPSYSDPYLEAVDIRQIYDKFPEKKGGLKDLFERGPSNAFFLVKFWADLNTNIEDEGSSFYGVSSQYESPENMIITCSTKVCSFGKQVVEKVETEYARYENGHYSYRIHRSPLCEYMINFIHKLKHLPEKYMMNSVLENFTILQVVTNRDTQETLLCIAYVFEVSASEHGAQHHIYRLVKE | Homo sapiens | Nucleus | Tissue enhanced (skeletal) | {'Ciliated cells': '3.1', 'Basal respiratory cells': '5.8', 'Club cells': '3.3', 'Ionocytes': '1.8', 'Mucus glandular cells': '4.4', 'Serous glandular cells': '0.2', 'Gastric mucus-secreting cells': '4.1', 'Proximal enterocytes': '38.7', 'Paneth cells': '1.0', 'Distal enterocytes': '2.1', 'Intestinal goblet cells': '4.3', 'Exocrine glandular cells': '-0.769', 'Basal prostatic cells': '23.6', 'Prostatic glandular cells': '1.2', 'Breast glandular cells': '0.070', 'Breast myoepithelial cells': '0.031', 'Glandular and luminal cells': '4.5', 'Secretory cells': '15.8', 'Basal keratinocytes': '9.8', 'Suprabasal keratinocytes': '4.3', 'Basal squamous epithelial cells': '9.1', 'Squamous epithelial cells': '3.8', 'Alveolar cells type 1': '0.130', 'Alveolar cells type 2': '-0.267', 'Salivary duct cells': '6.4', 'Ductal cells': '0.450', 'Hepatocytes': '0.207', 'Cholangiocytes': '5.7', 'Proximal tubular cells': '0.135', 'Distal tubular cells': '9.2', 'Collecting duct cells': '5.8', 'Mesothelial cells': '0.144', 'Sertoli cells': '0.440', 'Granulosa cells': '1.5', 'Enteroendocrine cells': '3.5', 'Pancreatic endocrine cells': '10.2', 'Leydig cells': '0.448', 'Excitatory neurons': '1.5', 'Inhibitory neurons': '0.5', 'Cone photoreceptor cells': '0.0', 'Rod photoreceptor cells': '0.0', 'Bipolar cells': '0.0', 'Horizontal cells': '0.6', 'Astrocytes': '0.0', 'Oligodendrocyte precursor cells': '0.0', 'Oligodendrocytes': '0.4', 'Microglial cells': '3.6', 'Muller glia cells': '0.4', 'Schwann cells': '0.082', 'Spermatogonia': '0.691', 'Spermatocytes': '0.170', 'Early spermatids': '-0.416', 'Late spermatids': '-0.398', 'Oocytes': '12.5', 'Cytotrophoblasts': '53.0', 'Syncytiotrophoblasts': '27.9', 'Extravillous trophoblasts': '13.4', 'Endothelial cells': '26.9', 'Lymphatic endothelial cells': '12.5', 'Cardiomyocytes': '0.071', 'Skeletal myocytes': '0.042', 'Smooth muscle cells': '10.1', 'Adipocytes': '15.8', 'Melanocytes': '0.092', 'Fibroblasts': '7.8', 'Peritubular cells': '0.232', 'Endometrial stromal cells': '5.4', 'Ovarian stromal cells': '1.0', 'Undifferentiated cells': '9.0', 'T-cells': '0.5', 'B-cells': '0.1', 'Plasma cells': '0.7', 'Nk-cells': '0.0', 'Granulocytes': '0.9', 'Monocytes': '0.0', 'Macrophages': '0.7', 'Hofbauer cells': '1.9', 'Kupffer cells': '0.7', 'Dendritic cells': '0.0', 'Langerhans cells': '0.060', 'Erythroid cells': '-0.044', 'Adipocytes (Subcutaneous)': '-0.315', 'Adipocytes (Visceral)': '-0.276', 'Breast glandular cells (progenitors)': '-0.098', 'Adipocytes (Breast)': '-0.151', 'Colon enterocytes': '-0.091', 'Colon enteroendocrine cells': '-0.009', 'Enteric glia cells': '0.182', 'Mitotic cells (Colon)': '0.170', 'Mitotic cells (Heart)': '0.359', 'Podocytes': '-0.068', 'Ascending Loop of Henle cells': '0.124', 'Intercalated cells': '-0.239', 'Cholangiocyte': '0.447', 'NK-cells (Liver)': '-0.317', 'Respiratory ciliated cells': '-0.096', 'Mitotic cells (Lung)': '-0.149', 'NK-cells (Lung)': '0.255', 'B-cells (Lung)': '-0.006', 'Alpha cells': '0.174', 'Beta cells': '0.101', 'Prostate glandular cells': '-0.340', 'Prostate basal glandular cells': '0.017', 'Urothelial cells': '0.103', 'Keratinocyte (other)': '0.281', 'Keratinocyte (granular)': '0.628', 'Hair cortex cells': '-0.265', 'Inner root sheath cells': '-0.282', 'Outer root sheath cells': '-0.520', 'Sebaceous gland cells': '-0.290', 'Eccrine sweat gland cells': '-0.388', 'Adipocytes (Skin)': '-0.222', 'Mitotic cells (Skin)': '-0.185', 'Parietal cells': '-0.704', 'Chief cells': '-0.573', 'Gastric mucous cells': '-0.354', 'Gastric enteroendocrine cells': '-0.381', 'Mitotic cells (Stomach)': '0.118', 'Parafollicular cells': '0.021', 'Thyroid glandular cells': '0.217', 'Mitotic cells (Thyroid)': '-0.216', 'Adrenal cortex cells': '0.240', 'Adrenal medulla cells': '0.066', 'Mitotic cells (Adrenal gland)': '0.041', 'Minor salivary glandular cells': '0.477', 'Minor salivary gland ductal cells': '-0.179', 'Minor salivary gland basal cells': '0.294', 'Mitotic cells (Minor salivary gland)': '0.479', 'Adipocytes (Minor salivary gland)': '0.233', 'Somatotropes': '-0.052', 'Lactotropes': '-0.377', 'Gonadotropes': '-0.279', 'Corticotropes': '-0.170', 'Thyrotropes': '-0.259', 'Undifferentiated cells (Pituitary gland)': '0.140', 'Mitotic cells (Spleen)': '-0.347', 'Platelets': '-0.172', 'Erythrocytes': '-0.100', 'Hematopoietic stem cells': '-0.319', 'B-cells (Spleen)': '0.019', 'NK-cells (Spleen)': '0.156', 'Amygdala excitatory': '0.7', 'Cerebellar inhibitory': '0.4', 'Cge interneuron': '0.5', 'Deep-layer corticothalamic and 6b': '0.3', 'Deep-layer intratelencephalic': '0.8', 'Deep-layer near-projecting': '0.4', 'Eccentric medium spiny neuron': '0.4', 'Hippocampal ca1-3': '0.7', 'Hippocampal ca4': '0.5', 'Hippocampal dentate gyrus': '2.1', 'Lamp5-lhx6 and chandelier': '1.0', 'Lower rhombic lip': '0.4', 'Mammillary body': '0.4', 'Medium spiny neuron': '0.9', 'Mge interneuron': '1.0', 'Midbrain-derived inhibitory': '0.2', 'Miscellaneous': '0.5', 'Splatter': '0.4', 'Thalamic excitatory': '1.9', 'Upper rhombic lip': '3.0', 'Upper-layer intratelencephalic': '1.4', 'Astrocyte': '0.5', 'Bergmann glia': '0.6', 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P14373 | Q9UHD2 | 29688809 | UbiBrowser | TRIM27 | MASGSVAECLQQETTCPVCLQYFAEPMMLDCGHNICCACLARCWGTAETNVSCPQCRETFPQRHMRPNRHLANVTQLVKQLRTERPSGPGGEMGVCEKHREPLKLYCEEDQMPICVVCDRSREHRGHSVLPLEEAVEGFKEQIQNQLDHLKRVKDLKKRRRAQGEQARAELLSLTQMEREKIVWEFEQLYHSLKEHEYRLLARLEELDLAIYNSINGAITQFSCNISHLSSLIAQLEEKQQQPTRELLQDIGDTLSRAERIRIPEPWITPPDLQEKIHIFAQKCLFLTESLKQFTEKMQSDMEKIQELREAQLYSVDVTLDPDTAYPSLILSDNLRQVRYSYLQQDLPDNPERFNLFPCVLGSPCFIAGRHYWEVEVGDKAKWTIGVCEDSVCRKGGVTSAPQNGFWAVSLWYGKEYWALTSPMTALPLRTPLQRVGIFLDYDAGEVSFYNVTERCHTFTFSHATFCGPVRPYFSLSYSGGKSAAPLIICPMSGIDGFSGHVGNHGHSMETSP | Homo sapiens | Nucleus, Cytoplasm, Nucleus, PML body, Early endosome, Mitochondrion | Low tissue specificity | {'Ciliated cells': '25.1', 'Basal respiratory cells': '27.3', 'Club cells': '24.7', 'Ionocytes': '23.2', 'Mucus glandular cells': '21.7', 'Serous glandular cells': '33.5', 'Gastric mucus-secreting cells': '23.6', 'Proximal enterocytes': '20.1', 'Paneth cells': '20.0', 'Distal enterocytes': '15.1', 'Intestinal goblet cells': '37.0', 'Exocrine glandular cells': '-0.693', 'Basal prostatic cells': '43.6', 'Prostatic glandular cells': '43.5', 'Breast glandular cells': '0.696', 'Breast myoepithelial cells': '0.544', 'Glandular and luminal cells': '29.8', 'Secretory cells': '37.3', 'Basal keratinocytes': '26.5', 'Suprabasal keratinocytes': '15.7', 'Basal squamous epithelial cells': '34.1', 'Squamous epithelial cells': '21.9', 'Alveolar cells type 1': '-0.038', 'Alveolar cells type 2': '-0.408', 'Salivary duct cells': '18.1', 'Ductal cells': '0.480', 'Hepatocytes': '0.177', 'Cholangiocytes': '22.9', 'Proximal tubular cells': '0.232', 'Distal tubular cells': '18.4', 'Collecting duct cells': '27.2', 'Mesothelial cells': '0.392', 'Sertoli cells': '0.703', 'Granulosa cells': '19.2', 'Enteroendocrine cells': '31.0', 'Pancreatic endocrine cells': '18.7', 'Leydig cells': '0.636', 'Excitatory neurons': '13.0', 'Inhibitory neurons': '12.8', 'Cone photoreceptor cells': '13.6', 'Rod photoreceptor cells': '11.3', 'Bipolar cells': '10.1', 'Horizontal cells': '7.6', 'Astrocytes': '11.1', 'Oligodendrocyte precursor cells': '17.9', 'Oligodendrocytes': '18.4', 'Microglial cells': '16.1', 'Muller glia cells': '12.1', 'Schwann cells': '0.026', 'Spermatogonia': '0.420', 'Spermatocytes': '-0.042', 'Early spermatids': '-0.589', 'Late spermatids': '-0.706', 'Oocytes': '13.2', 'Cytotrophoblasts': '48.8', 'Syncytiotrophoblasts': '50.5', 'Extravillous trophoblasts': '58.8', 'Endothelial cells': '27.6', 'Lymphatic endothelial cells': '18.3', 'Cardiomyocytes': '0.444', 'Skeletal myocytes': '-0.371', 'Smooth muscle cells': '19.7', 'Adipocytes': '20.7', 'Melanocytes': '-0.177', 'Fibroblasts': '22.4', 'Peritubular cells': '0.559', 'Endometrial stromal cells': '27.3', 'Ovarian stromal cells': '24.5', 'Undifferentiated cells': '29.3', 'T-cells': '28.5', 'B-cells': '33.6', 'Plasma cells': '50.4', 'Nk-cells': '25.7', 'Granulocytes': '27.4', 'Monocytes': '32.5', 'Macrophages': '29.6', 'Hofbauer cells': '38.9', 'Kupffer cells': '31.1', 'Dendritic cells': '32.8', 'Langerhans cells': '0.075', 'Erythroid cells': '-0.057', 'Adipocytes (Subcutaneous)': '-0.199', 'Adipocytes (Visceral)': '-0.372', 'Breast glandular cells (progenitors)': '0.493', 'Adipocytes (Breast)': '-0.659', 'Colon enterocytes': '-0.039', 'Colon enteroendocrine cells': '0.155', 'Enteric glia cells': '0.411', 'Mitotic cells (Colon)': '0.069', 'Mitotic cells (Heart)': '0.481', 'Podocytes': '-0.080', 'Ascending Loop of Henle cells': '0.332', 'Intercalated cells': '-0.067', 'Cholangiocyte': '0.283', 'NK-cells (Liver)': '-0.293', 'Respiratory ciliated cells': '0.036', 'Mitotic cells (Lung)': '-0.109', 'NK-cells (Lung)': '0.295', 'B-cells (Lung)': '0.112', 'Alpha cells': '0.335', 'Beta cells': '0.170', 'Prostate glandular cells': '0.251', 'Prostate basal glandular cells': '0.383', 'Urothelial cells': '0.310', 'Keratinocyte (other)': '-0.109', 'Keratinocyte (granular)': '-0.354', 'Hair cortex cells': '0.029', 'Inner root sheath cells': '0.037', 'Outer root sheath cells': '0.284', 'Sebaceous gland cells': '0.136', 'Eccrine sweat gland cells': '0.208', 'Adipocytes (Skin)': '0.020', 'Mitotic cells (Skin)': '0.110', 'Parietal cells': '-0.236', 'Chief cells': '-0.025', 'Gastric mucous cells': '0.098', 'Gastric enteroendocrine cells': '0.091', 'Mitotic cells (Stomach)': '0.263', 'Parafollicular cells': '0.070', 'Thyroid glandular cells': '0.072', 'Mitotic cells (Thyroid)': '0.055', 'Adrenal cortex cells': '0.312', 'Adrenal medulla cells': '-0.104', 'Mitotic cells (Adrenal gland)': '-0.086', 'Minor salivary glandular cells': '0.517', 'Minor salivary gland ductal cells': '0.287', 'Minor salivary gland basal cells': '-0.017', 'Mitotic cells (Minor salivary gland)': '0.010', 'Adipocytes (Minor salivary gland)': '0.057', 'Somatotropes': '0.482', 'Lactotropes': '0.227', 'Gonadotropes': '0.066', 'Corticotropes': '0.019', 'Thyrotropes': '0.026', 'Undifferentiated cells (Pituitary gland)': '-0.250', 'Mitotic cells (Spleen)': '-0.238', 'Platelets': '-0.171', 'Erythrocytes': '-0.096', 'Hematopoietic stem cells': '-0.313', 'B-cells (Spleen)': '0.377', 'NK-cells (Spleen)': '0.278', 'Amygdala excitatory': '29.4', 'Cerebellar inhibitory': '15.3', 'Cge interneuron': '27.6', 'Deep-layer corticothalamic and 6b': '29.3', 'Deep-layer intratelencephalic': '31.8', 'Deep-layer near-projecting': '34.8', 'Eccentric medium spiny neuron': '27.3', 'Hippocampal ca1-3': '26.5', 'Hippocampal ca4': '28.4', 'Hippocampal dentate gyrus': '29.8', 'Lamp5-lhx6 and chandelier': '22.8', 'Lower rhombic lip': '32.2', 'Mammillary body': '18.8', 'Medium spiny neuron': '22.8', 'Mge interneuron': '26.6', 'Midbrain-derived inhibitory': '28.4', 'Miscellaneous': '30.0', 'Splatter': '27.8', 'Thalamic excitatory': '23.9', 'Upper rhombic lip': '24.1', 'Upper-layer intratelencephalic': '28.8', 'Astrocyte': '26.3', 'Bergmann glia': '25.2', 'Central nervous system macrophage': '78.3', 'Choroid plexus epithelial cell': '42.9', 'Committed oligodendrocyte precursor': '33.8', 'Ependymal cell': '20.3', 'Oligodendrocyte': '36.0', 'Oligodendrocyte precursor cell': '32.2', 'Endothelial cell': '58.5', 'Pericyte': '33.4', 'Vascular associated smooth muscle cell': '31.7', 'Fibroblast': '43.5', 'Leukocyte': '58.3', 'Basophil': '20.3', 'Eosinophil': '2.5', 'Neutrophil': '51.3', 'Classical monocyte': '17.4', 'Non-classical monocyte': '33.2', 'Intermediate monocyte': '36.3', 'T-reg': '19.6', 'GdT-cell': '7.2', 'MAIT T-cell': '29.7', 'Memory CD4 T-cell': '10.6', 'Naive CD4 T-cell': '29.7', 'Memory CD8 T-cell': '5.6', 'Naive CD8 T-cell': '28.3', 'Memory B-cell': '7.1', 'Naive B-cell': '18.7', 'Plasmacytoid DC': '27.3', 'Myeloid DC': '30.5', 'NK-cell': '26.2', 'Total PBMC': '23.0', 'Vd2 gdTCR': '19.2', 'Memory CD4 T-cell Th1\\/Th17': '22.6', 'Memory CD4 T-cell Th17': '23.3', 'Memory CD4 T-cell Th2': '23.3', 'Non-Vd2 gdTCR': '18.3', 'Memory CD4 T-cell Th1': '23.8', 'Memory CD4 T-cell TFH': '24.9', 'Terminal effector memory CD4 T-cell': '26.8', 'Central memory CD8 T-cell': '23.4', 'Effector memory CD8 T-cell': '21.7', 'Terminal effector memory CD8 T-cell': '14.3', 'Non-switched memory B-cell': '22.5', 'Plasmablast': '44.1', 'Switched memory B-cell': '25.7', 'Exhausted memory B-cell': '13.9', 'Progenitor cell': '20.6', 'Memory T-reg': '26.0', 'Naive CD4 T-cell activated': '55.5', 'Naive CD8 T-cell activated': '61.3', 'Naive T-reg': '32.5'} | null | {'Adipose Tissue': 30.51002491694352, 'Adrenal Gland': 28.42209302325581, 'Bladder': 42.15761904761904, 'Blood': 47.71387405812702, 'Blood Vessel': 35.17883895131086, 'Brain': 17.082769114307343, 'Breast': 35.04257080610022, 'Cervix Uteri': 56.090526315789475, 'Colon': 26.715078305519896, 'Esophagus': 25.588709342560552, 'Fallopian Tube': 54.83888888888889, 'Heart': 12.228174216027876, 'Kidney': 20.893404494382025, 'Liver': 28.784889380530977, 'Lung': 43.63569204152249, 'Muscle': 13.141891656288918, 'Nerve': 43.2170436187399, 'Ovary': 50.49094444444445, 'Pancreas': 26.43318292682927, 'Pituitary': 49.52038869257951, 'Prostate': 47.70363265306122, 'Salivary Gland': 32.1683950617284, 'Skin': 30.310514648977335, 'Small Intestine': 34.5279679144385, 'Spleen': 56.557759336099586, 'Stomach': 26.06833704735376, 'Testis': 26.19157894736842, 'Thyroid': 45.41816232771823, 'Uterus': 52.2319014084507, 'Vagina': 36.81769230769231} | TBK1 | MQSTSNHLWLLSDILGQGATANVFRGRHKKTGDLFAIKVFNNISFLRPVDVQMREFEVLKKLNHKNIVKLFAIEEETTTRHKVLIMEFCPCGSLYTVLEEPSNAYGLPESEFLIVLRDVVGGMNHLRENGIVHRDIKPGNIMRVIGEDGQSVYKLTDFGAARELEDDEQFVSLYGTEEYLHPDMYERAVLRKDHQKKYGATVDLWSIGVTFYHAATGSLPFRPFEGPRRNKEVMYKIITGKPSGAISGVQKAENGPIDWSGDMPVSCSLSRGLQVLLTPVLANILEADQEKCWGFDQFFAETSDILHRMVIHVFSLQQMTAHKIYIHSYNTATIFHELVYKQTKIISSNQELIYEGRRLVLEPGRLAQHFPKTTEENPIFVVSREPLNTIGLIYEKISLPKVHPRYDLDGDASMAKAITGVVCYACRIASTLLLYQELMRKGIRWLIELIKDDYNETVHKKTEVVITLDFCIRNIEKTVKVYEKLMKINLEAAELGEISDIHTKLLRLSSSQGTIETSLQDIDSRLSPGGSLADAWAHQEGTHPKDRNVEKLQVLLNCMTEIYYQFKKDKAERRLAYNEEQIHKFDKQKLYYHATKAMTHFTDECVKKYEAFLNKSEEWIRKMLHLRKQLLSLTNQCFDIEEEVSKYQEYTNELQETLPQKMFTASSGIKHTMTPIYPSSNTLVEMTLGMKKLKEEMEGVVKELAENNHILERFGSLTMDGGLRNVDCL | Homo sapiens | Cytoplasm | Low tissue specificity | {'Ciliated cells': '34.3', 'Basal respiratory cells': '48.3', 'Club cells': '39.6', 'Ionocytes': '82.8', 'Mucus glandular cells': '57.4', 'Serous glandular cells': '23.5', 'Gastric mucus-secreting cells': '18.9', 'Proximal enterocytes': '30.4', 'Paneth cells': '31.8', 'Distal enterocytes': '22.0', 'Intestinal goblet cells': '23.2', 'Exocrine glandular cells': '-0.684', 'Basal prostatic cells': '30.5', 'Prostatic glandular cells': '42.2', 'Breast glandular cells': '0.343', 'Breast myoepithelial cells': '0.354', 'Glandular and luminal cells': '54.0', 'Secretory cells': '31.8', 'Basal keratinocytes': '21.6', 'Suprabasal keratinocytes': '25.1', 'Basal squamous epithelial cells': '15.3', 'Squamous epithelial cells': '17.8', 'Alveolar cells type 1': '0.208', 'Alveolar cells type 2': '-0.095', 'Salivary duct cells': '33.6', 'Ductal cells': '0.630', 'Hepatocytes': '0.327', 'Cholangiocytes': '17.2', 'Proximal tubular cells': '0.176', 'Distal tubular cells': '9.2', 'Collecting duct cells': '35.0', 'Mesothelial cells': '0.267', 'Sertoli cells': '-0.066', 'Granulosa cells': '27.1', 'Enteroendocrine cells': '21.7', 'Pancreatic endocrine cells': '18.7', 'Leydig cells': '-0.120', 'Excitatory neurons': '48.8', 'Inhibitory neurons': '40.4', 'Cone photoreceptor cells': '32.3', 'Rod photoreceptor cells': '49.1', 'Bipolar cells': '42.6', 'Horizontal cells': '51.0', 'Astrocytes': '26.9', 'Oligodendrocyte precursor cells': '36.8', 'Oligodendrocytes': '48.7', 'Microglial cells': '44.7', 'Muller glia cells': '19.6', 'Schwann cells': '0.105', 'Spermatogonia': '0.177', 'Spermatocytes': '0.581', 'Early spermatids': '0.644', 'Late spermatids': '0.071', 'Oocytes': '14.0', 'Cytotrophoblasts': '49.3', 'Syncytiotrophoblasts': '168.8', 'Extravillous trophoblasts': '77.1', 'Endothelial cells': '37.9', 'Lymphatic endothelial cells': '52.9', 'Cardiomyocytes': '0.540', 'Skeletal myocytes': '-0.323', 'Smooth muscle cells': '30.0', 'Adipocytes': '43.6', 'Melanocytes': '0.001', 'Fibroblasts': '32.4', 'Peritubular cells': '-0.033', 'Endometrial stromal cells': '32.9', 'Ovarian stromal cells': '35.3', 'Undifferentiated cells': '17.7', 'T-cells': '40.1', 'B-cells': '39.1', 'Plasma cells': '29.5', 'Nk-cells': '80.7', 'Granulocytes': '74.0', 'Monocytes': '195.8', 'Macrophages': '58.7', 'Hofbauer cells': '37.4', 'Kupffer cells': '40.6', 'Dendritic cells': '20.4', 'Langerhans cells': '0.124', 'Erythroid cells': '-0.045', 'Adipocytes (Subcutaneous)': '-0.279', 'Adipocytes (Visceral)': '-0.332', 'Breast glandular cells (progenitors)': '0.203', 'Adipocytes (Breast)': '-0.318', 'Colon enterocytes': '-0.084', 'Colon enteroendocrine cells': '0.277', 'Enteric glia cells': '-0.056', 'Mitotic cells (Colon)': '0.037', 'Mitotic cells (Heart)': '0.503', 'Podocytes': '-0.027', 'Ascending Loop of Henle cells': '0.319', 'Intercalated cells': '-0.100', 'Cholangiocyte': '0.343', 'NK-cells (Liver)': '-0.315', 'Respiratory ciliated cells': '-0.020', 'Mitotic cells (Lung)': '-0.107', 'NK-cells (Lung)': '0.367', 'B-cells (Lung)': '0.135', 'Alpha cells': '0.406', 'Beta cells': '0.201', 'Prostate glandular cells': '-0.033', 'Prostate basal glandular cells': '0.278', 'Urothelial cells': '0.201', 'Keratinocyte (other)': '-0.023', 'Keratinocyte (granular)': '-0.127', 'Hair cortex cells': '-0.037', 'Inner root sheath cells': '0.019', 'Outer root sheath cells': '0.139', 'Sebaceous gland cells': '0.016', 'Eccrine sweat gland cells': '0.074', 'Adipocytes (Skin)': '0.028', 'Mitotic cells (Skin)': '0.156', 'Parietal cells': '-0.577', 'Chief cells': '-0.512', 'Gastric mucous cells': '-0.217', 'Gastric enteroendocrine cells': '-0.378', 'Mitotic cells (Stomach)': '0.185', 'Parafollicular cells': '0.042', 'Thyroid glandular cells': '0.275', 'Mitotic cells (Thyroid)': '0.059', 'Adrenal cortex cells': '0.656', 'Adrenal medulla cells': '0.065', 'Mitotic cells (Adrenal gland)': '0.476', 'Minor salivary glandular cells': '0.612', 'Minor salivary gland ductal cells': '0.021', 'Minor salivary gland basal cells': '0.402', 'Mitotic cells (Minor salivary gland)': '0.466', 'Adipocytes (Minor salivary gland)': '0.128', 'Somatotropes': '0.282', 'Lactotropes': '0.122', 'Gonadotropes': '-0.010', 'Corticotropes': '-0.165', 'Thyrotropes': '0.042', 'Undifferentiated cells (Pituitary gland)': '-0.088', 'Mitotic cells (Spleen)': '-0.131', 'Platelets': '-0.080', 'Erythrocytes': '-0.085', 'Hematopoietic stem cells': '-0.214', 'B-cells (Spleen)': '0.294', 'NK-cells (Spleen)': '0.290', 'Amygdala excitatory': '63.7', 'Cerebellar inhibitory': '64.5', 'Cge interneuron': '54.9', 'Deep-layer corticothalamic and 6b': '68.3', 'Deep-layer intratelencephalic': '66.3', 'Deep-layer near-projecting': '102.4', 'Eccentric medium spiny neuron': '64.9', 'Hippocampal ca1-3': '61.3', 'Hippocampal ca4': '68.9', 'Hippocampal dentate gyrus': '58.2', 'Lamp5-lhx6 and chandelier': '60.1', 'Lower rhombic lip': '85.9', 'Mammillary body': '67.6', 'Medium spiny neuron': '57.0', 'Mge interneuron': '65.7', 'Midbrain-derived inhibitory': '66.3', 'Miscellaneous': '56.3', 'Splatter': '67.4', 'Thalamic excitatory': '126.4', 'Upper rhombic lip': '63.5', 'Upper-layer intratelencephalic': '71.3', 'Astrocyte': '55.5', 'Bergmann glia': '56.0', 'Central nervous system macrophage': '114.1', 'Choroid plexus epithelial cell': '65.5', 'Committed oligodendrocyte precursor': '54.0', 'Ependymal cell': '37.9', 'Oligodendrocyte': '78.4', 'Oligodendrocyte precursor cell': '57.9', 'Endothelial cell': '102.5', 'Pericyte': '62.5', 'Vascular associated smooth muscle cell': '60.8', 'Fibroblast': '84.0', 'Leukocyte': '80.3', 'Basophil': '57.1', 'Eosinophil': '24.5', 'Neutrophil': '57.6', 'Classical monocyte': '36.6', 'Non-classical monocyte': '60.6', 'Intermediate monocyte': '46.0', 'T-reg': '23.6', 'GdT-cell': '14.0', 'MAIT T-cell': '25.0', 'Memory CD4 T-cell': '10.2', 'Naive CD4 T-cell': '11.8', 'Memory CD8 T-cell': '15.2', 'Naive CD8 T-cell': '12.9', 'Memory B-cell': '12.9', 'Naive B-cell': '35.2', 'Plasmacytoid DC': '11.7', 'Myeloid DC': '36.5', 'NK-cell': '66.8', 'Total PBMC': '28.1', 'Vd2 gdTCR': '47.3', 'Memory CD4 T-cell TFH': '26.7', 'Memory CD4 T-cell Th2': '37.5', 'Memory CD4 T-cell Th17': '35.6', 'Memory CD4 T-cell Th1\\/Th17': '47.7', 'Non-Vd2 gdTCR': '50.0', 'Memory CD4 T-cell Th1': '35.7', 'Terminal effector memory CD4 T-cell': '44.5', 'Central memory CD8 T-cell': '19.5', 'Effector memory CD8 T-cell': '44.2', 'Terminal effector memory CD8 T-cell': '46.4', 'Switched memory B-cell': '28.9', 'Plasmablast': '37.0', 'Non-switched memory B-cell': '20.5', 'Exhausted memory B-cell': '21.3', 'Progenitor cell': '9.8', 'Naive CD4 T-cell activated': '5.5', 'Naive CD8 T-cell activated': '6.9', 'Memory T-reg': '40.9', 'Naive T-reg': '20.4'} | 4EFO, 4EUT, 4EUU, 4IM0, 4IM2, 4IM3, 4IW0, 4IWO, 4IWP, 4IWQ, 5EOA, 5EOF, 5EP6, 5W5V, 6BNY, 6BOD, 6BOE, 6CQ0, 6CQ4, 6CQ5, 6NT9, 6O8B, 6RSR, 6RST, 6RSU | {'Adipose Tissue': 25.14706063122924, 'Adrenal Gland': 27.124589147286823, 'Bladder': 25.653333333333336, 'Blood': 17.975826695371367, 'Blood Vessel': 26.485053932584268, 'Brain': 13.811599545798638, 'Breast': 25.65735947712418, 'Cervix Uteri': 28.643684210526317, 'Colon': 21.12450706033376, 'Esophagus': 21.544210380622836, 'Fallopian Tube': 27.333333333333332, 'Heart': 8.100483507549361, 'Kidney': 11.153629213483146, 'Liver': 11.378650442477875, 'Lung': 33.63641868512111, 'Muscle': 18.001170610211705, 'Nerve': 27.994442649434575, 'Ovary': 25.219444444444445, 'Pancreas': 6.630317073170732, 'Pituitary': 23.795088339222616, 'Prostate': 24.6145306122449, 'Salivary Gland': 20.22978395061728, 'Skin': 23.38969485903814, 'Small Intestine': 23.96101604278075, 'Spleen': 29.430497925311204, 'Stomach': 17.541384401114207, 'Testis': 44.16016620498615, 'Thyroid': 24.114961715160796, 'Uterus': 30.87718309859155, 'Vagina': 26.03076923076923} | [31.5, 48.3, 47.93, 54.46, 74.47, 78.85, 76.74, 76.48, 83.58, 84.99, 84.08, 86.19, 90.37, 91.51, 93.16, 94.46, 92.4, 92.37, 93.5, 90.87, 91.73, 91.32, 93.76, 91.13, 92.38, 94.72, 94.57, 95.42, 93.29, 91.17, 93.58, 92.64, 94.87, 95.5, 95.31, 95.76, 93.38, 92.94, 94.51, 91.84, 90.28, 90.83, 88.2, 90.02, 85.2, 83.0, 81.16, 78.84, 84.16, 85.85, 90.36, 91.7, 93.97, 91.39, 91.64, 93.8, 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0.28, 0.03, 0.4, 0.53, 0.12, 0.4, 0.74, 0.39, 0.14, 0.52, 0.68, 0.37, 0.42, 0.8, 0.68, 0.59, 0.59, 0.83, 0.95, 0.76, 0.99, 0.79, 0.98, 0.89, 0.88, 0.71, 0.89, 0.82, 0.92, 0.52, 0.65, 0.64, 0.49, 0.72, 0.54, 0.66, 0.6, 0.59, 0.63, 0.46, 0.67, 0.66, 0.6, 0.53, 0.6, 0.6, 0.52, 0.61, 0.56, 0.39, 0.53, 0.64, 0.63, 0.61, 0.55, 0.56, 0.54, 0.51, 0.45, 0.58, 0.49, 0.64, 0.45, 0.68, 0.59, 0.36, 0.64, 0.73, 0.66, 0.89, 0.83, 0.74, 0.7, 0.88, 0.91, 0.82, 0.86, 0.9, 0.94, 0.98] | RING finger | Part of a complex consisting of TRIM27, USP7 and MAGEL2 | null | null | EID1, MAGED4, MAGEF1, SQSTM1, EPC1, CHD4, MAGEL2, PML, EIF3S6, PTPN11, USP7, | PIK3C2B, WASHC1, TBK1, NOD2,ULK1, STK38L | 48, 63 | null | null | Homomultimerizes | null | 88.603957 | 0.43115 | 89.656872 | 0.338313 | 950 |
P14373 | Q9Y6X2 | 31747314 | UbiBrowser | TRIM27 | MASGSVAECLQQETTCPVCLQYFAEPMMLDCGHNICCACLARCWGTAETNVSCPQCRETFPQRHMRPNRHLANVTQLVKQLRTERPSGPGGEMGVCEKHREPLKLYCEEDQMPICVVCDRSREHRGHSVLPLEEAVEGFKEQIQNQLDHLKRVKDLKKRRRAQGEQARAELLSLTQMEREKIVWEFEQLYHSLKEHEYRLLARLEELDLAIYNSINGAITQFSCNISHLSSLIAQLEEKQQQPTRELLQDIGDTLSRAERIRIPEPWITPPDLQEKIHIFAQKCLFLTESLKQFTEKMQSDMEKIQELREAQLYSVDVTLDPDTAYPSLILSDNLRQVRYSYLQQDLPDNPERFNLFPCVLGSPCFIAGRHYWEVEVGDKAKWTIGVCEDSVCRKGGVTSAPQNGFWAVSLWYGKEYWALTSPMTALPLRTPLQRVGIFLDYDAGEVSFYNVTERCHTFTFSHATFCGPVRPYFSLSYSGGKSAAPLIICPMSGIDGFSGHVGNHGHSMETSP | Homo sapiens | Nucleus, Cytoplasm, Nucleus, PML body, Early endosome, Mitochondrion | Low tissue specificity | {'Ciliated cells': '25.1', 'Basal respiratory cells': '27.3', 'Club cells': '24.7', 'Ionocytes': '23.2', 'Mucus glandular cells': '21.7', 'Serous glandular cells': '33.5', 'Gastric mucus-secreting cells': '23.6', 'Proximal enterocytes': '20.1', 'Paneth cells': '20.0', 'Distal enterocytes': '15.1', 'Intestinal goblet cells': '37.0', 'Exocrine glandular cells': '-0.693', 'Basal prostatic cells': '43.6', 'Prostatic glandular cells': '43.5', 'Breast glandular cells': '0.696', 'Breast myoepithelial cells': '0.544', 'Glandular and luminal cells': '29.8', 'Secretory cells': '37.3', 'Basal keratinocytes': '26.5', 'Suprabasal keratinocytes': '15.7', 'Basal squamous epithelial cells': '34.1', 'Squamous epithelial cells': '21.9', 'Alveolar cells type 1': '-0.038', 'Alveolar cells type 2': '-0.408', 'Salivary duct cells': '18.1', 'Ductal cells': '0.480', 'Hepatocytes': '0.177', 'Cholangiocytes': '22.9', 'Proximal tubular cells': '0.232', 'Distal tubular cells': '18.4', 'Collecting duct cells': '27.2', 'Mesothelial cells': '0.392', 'Sertoli cells': '0.703', 'Granulosa cells': '19.2', 'Enteroendocrine cells': '31.0', 'Pancreatic endocrine cells': '18.7', 'Leydig cells': '0.636', 'Excitatory neurons': '13.0', 'Inhibitory neurons': '12.8', 'Cone photoreceptor cells': '13.6', 'Rod photoreceptor cells': '11.3', 'Bipolar cells': '10.1', 'Horizontal cells': '7.6', 'Astrocytes': '11.1', 'Oligodendrocyte precursor cells': '17.9', 'Oligodendrocytes': '18.4', 'Microglial cells': '16.1', 'Muller glia cells': '12.1', 'Schwann cells': '0.026', 'Spermatogonia': '0.420', 'Spermatocytes': '-0.042', 'Early spermatids': '-0.589', 'Late spermatids': '-0.706', 'Oocytes': '13.2', 'Cytotrophoblasts': '48.8', 'Syncytiotrophoblasts': '50.5', 'Extravillous trophoblasts': '58.8', 'Endothelial cells': '27.6', 'Lymphatic endothelial cells': '18.3', 'Cardiomyocytes': '0.444', 'Skeletal myocytes': '-0.371', 'Smooth muscle cells': '19.7', 'Adipocytes': '20.7', 'Melanocytes': '-0.177', 'Fibroblasts': '22.4', 'Peritubular cells': '0.559', 'Endometrial stromal cells': '27.3', 'Ovarian stromal cells': '24.5', 'Undifferentiated cells': '29.3', 'T-cells': '28.5', 'B-cells': '33.6', 'Plasma cells': '50.4', 'Nk-cells': '25.7', 'Granulocytes': '27.4', 'Monocytes': '32.5', 'Macrophages': '29.6', 'Hofbauer cells': '38.9', 'Kupffer cells': '31.1', 'Dendritic cells': '32.8', 'Langerhans cells': '0.075', 'Erythroid cells': '-0.057', 'Adipocytes (Subcutaneous)': '-0.199', 'Adipocytes (Visceral)': '-0.372', 'Breast glandular cells (progenitors)': '0.493', 'Adipocytes (Breast)': '-0.659', 'Colon enterocytes': '-0.039', 'Colon enteroendocrine cells': '0.155', 'Enteric glia cells': '0.411', 'Mitotic cells (Colon)': '0.069', 'Mitotic cells (Heart)': '0.481', 'Podocytes': '-0.080', 'Ascending Loop of Henle cells': '0.332', 'Intercalated cells': '-0.067', 'Cholangiocyte': '0.283', 'NK-cells (Liver)': '-0.293', 'Respiratory ciliated cells': '0.036', 'Mitotic cells (Lung)': '-0.109', 'NK-cells (Lung)': '0.295', 'B-cells (Lung)': '0.112', 'Alpha cells': '0.335', 'Beta cells': '0.170', 'Prostate glandular cells': '0.251', 'Prostate basal glandular cells': '0.383', 'Urothelial cells': '0.310', 'Keratinocyte (other)': '-0.109', 'Keratinocyte (granular)': '-0.354', 'Hair cortex cells': '0.029', 'Inner root sheath cells': '0.037', 'Outer root sheath cells': '0.284', 'Sebaceous gland cells': '0.136', 'Eccrine sweat gland cells': '0.208', 'Adipocytes (Skin)': '0.020', 'Mitotic cells (Skin)': '0.110', 'Parietal cells': '-0.236', 'Chief cells': '-0.025', 'Gastric mucous cells': '0.098', 'Gastric enteroendocrine cells': '0.091', 'Mitotic cells (Stomach)': '0.263', 'Parafollicular cells': '0.070', 'Thyroid glandular cells': '0.072', 'Mitotic cells (Thyroid)': '0.055', 'Adrenal cortex cells': '0.312', 'Adrenal medulla cells': '-0.104', 'Mitotic cells (Adrenal gland)': '-0.086', 'Minor salivary glandular cells': '0.517', 'Minor salivary gland ductal cells': '0.287', 'Minor salivary gland basal cells': '-0.017', 'Mitotic cells (Minor salivary gland)': '0.010', 'Adipocytes (Minor salivary gland)': '0.057', 'Somatotropes': '0.482', 'Lactotropes': '0.227', 'Gonadotropes': '0.066', 'Corticotropes': '0.019', 'Thyrotropes': '0.026', 'Undifferentiated cells (Pituitary gland)': '-0.250', 'Mitotic cells (Spleen)': '-0.238', 'Platelets': '-0.171', 'Erythrocytes': '-0.096', 'Hematopoietic stem cells': '-0.313', 'B-cells (Spleen)': '0.377', 'NK-cells (Spleen)': '0.278', 'Amygdala excitatory': '29.4', 'Cerebellar inhibitory': '15.3', 'Cge interneuron': '27.6', 'Deep-layer corticothalamic and 6b': '29.3', 'Deep-layer intratelencephalic': '31.8', 'Deep-layer near-projecting': '34.8', 'Eccentric medium spiny neuron': '27.3', 'Hippocampal ca1-3': '26.5', 'Hippocampal ca4': '28.4', 'Hippocampal dentate gyrus': '29.8', 'Lamp5-lhx6 and chandelier': '22.8', 'Lower rhombic lip': '32.2', 'Mammillary body': '18.8', 'Medium spiny neuron': '22.8', 'Mge interneuron': '26.6', 'Midbrain-derived inhibitory': '28.4', 'Miscellaneous': '30.0', 'Splatter': '27.8', 'Thalamic excitatory': '23.9', 'Upper rhombic lip': '24.1', 'Upper-layer intratelencephalic': '28.8', 'Astrocyte': '26.3', 'Bergmann glia': '25.2', 'Central nervous system macrophage': '78.3', 'Choroid plexus epithelial cell': '42.9', 'Committed oligodendrocyte precursor': '33.8', 'Ependymal cell': '20.3', 'Oligodendrocyte': '36.0', 'Oligodendrocyte precursor cell': '32.2', 'Endothelial cell': '58.5', 'Pericyte': '33.4', 'Vascular associated smooth muscle cell': '31.7', 'Fibroblast': '43.5', 'Leukocyte': '58.3', 'Basophil': '20.3', 'Eosinophil': '2.5', 'Neutrophil': '51.3', 'Classical monocyte': '17.4', 'Non-classical monocyte': '33.2', 'Intermediate monocyte': '36.3', 'T-reg': '19.6', 'GdT-cell': '7.2', 'MAIT T-cell': '29.7', 'Memory CD4 T-cell': '10.6', 'Naive CD4 T-cell': '29.7', 'Memory CD8 T-cell': '5.6', 'Naive CD8 T-cell': '28.3', 'Memory B-cell': '7.1', 'Naive B-cell': '18.7', 'Plasmacytoid DC': '27.3', 'Myeloid DC': '30.5', 'NK-cell': '26.2', 'Total PBMC': '23.0', 'Vd2 gdTCR': '19.2', 'Memory CD4 T-cell Th1\\/Th17': '22.6', 'Memory CD4 T-cell Th17': '23.3', 'Memory CD4 T-cell Th2': '23.3', 'Non-Vd2 gdTCR': '18.3', 'Memory CD4 T-cell Th1': '23.8', 'Memory CD4 T-cell TFH': '24.9', 'Terminal effector memory CD4 T-cell': '26.8', 'Central memory CD8 T-cell': '23.4', 'Effector memory CD8 T-cell': '21.7', 'Terminal effector memory CD8 T-cell': '14.3', 'Non-switched memory B-cell': '22.5', 'Plasmablast': '44.1', 'Switched memory B-cell': '25.7', 'Exhausted memory B-cell': '13.9', 'Progenitor cell': '20.6', 'Memory T-reg': '26.0', 'Naive CD4 T-cell activated': '55.5', 'Naive CD8 T-cell activated': '61.3', 'Naive T-reg': '32.5'} | null | {'Adipose Tissue': 30.51002491694352, 'Adrenal Gland': 28.42209302325581, 'Bladder': 42.15761904761904, 'Blood': 47.71387405812702, 'Blood Vessel': 35.17883895131086, 'Brain': 17.082769114307343, 'Breast': 35.04257080610022, 'Cervix Uteri': 56.090526315789475, 'Colon': 26.715078305519896, 'Esophagus': 25.588709342560552, 'Fallopian Tube': 54.83888888888889, 'Heart': 12.228174216027876, 'Kidney': 20.893404494382025, 'Liver': 28.784889380530977, 'Lung': 43.63569204152249, 'Muscle': 13.141891656288918, 'Nerve': 43.2170436187399, 'Ovary': 50.49094444444445, 'Pancreas': 26.43318292682927, 'Pituitary': 49.52038869257951, 'Prostate': 47.70363265306122, 'Salivary Gland': 32.1683950617284, 'Skin': 30.310514648977335, 'Small Intestine': 34.5279679144385, 'Spleen': 56.557759336099586, 'Stomach': 26.06833704735376, 'Testis': 26.19157894736842, 'Thyroid': 45.41816232771823, 'Uterus': 52.2319014084507, 'Vagina': 36.81769230769231} | PIAS3 | MAELGELKHMVMSFRVSELQVLLGFAGRNKSGRKHELLAKALHLLKSSCAPSVQMKIKELYRRRFPRKTLGPSDLSLLSLPPGTSPVGSPGPLAPIPPTLLAPGTLLGPKREVDMHPPLPQPVHPDVTMKPLPFYEVYGELIRPTTLASTSSQRFEEAHFTFALTPQQVQQILTSREVLPGAKCDYTIQVQLRFCLCETSCPQEDYFPPNLFVKVNGKLCPLPGYLPPTKNGAEPKRPSRPINITPLARLSATVPNTIVVNWSSEFGRNYSLSVYLVRQLTAGTLLQKLRAKGIRNPDHSRALIKEKLTADPDSEVATTSLRVSLMCPLGKMRLTVPCRALTCAHLQSFDAALYLQMNEKKPTWTCPVCDKKAPYESLIIDGLFMEILSSCSDCDEIQFMEDGSWCPMKPKKEASEVCPPPGYGLDGLQYSPVQGGDPSENKKKVEVIDLTIESSSDEEDLPPTKKHCSVTSAAIPALPGSKGVLTSGHQPSSVLRSPAMGTLGGDFLSSLPLHEYPPAFPLGADIQGLDLFSFLQTESQHYGPSVITSLDEQDALGHFFQYRGTPSHFLGPLAPTLGSSHCSATPAPPPGRVSSIVAPGGALREGHGGPLPSGPSLTGCRSDIISLD | Homo sapiens | Cytoplasm, Nucleus, Nucleus speckle | Low tissue specificity | {'Ciliated cells': '28.2', 'Basal respiratory cells': '14.3', 'Club cells': '17.6', 'Ionocytes': '24.3', 'Mucus glandular cells': '6.5', 'Serous glandular cells': '10.8', 'Gastric mucus-secreting cells': '12.4', 'Proximal enterocytes': '1.6', 'Paneth cells': '2.0', 'Distal enterocytes': '1.8', 'Intestinal goblet cells': '6.4', 'Exocrine glandular cells': '-0.569', 'Basal prostatic cells': '17.7', 'Prostatic glandular cells': '10.1', 'Breast glandular cells': '0.705', 'Breast myoepithelial cells': '0.575', 'Glandular and luminal cells': '19.2', 'Secretory cells': '8.2', 'Basal keratinocytes': '12.2', 'Suprabasal keratinocytes': '19.5', 'Basal squamous epithelial cells': '15.5', 'Squamous epithelial cells': '20.7', 'Alveolar cells type 1': '-0.116', 'Alveolar cells type 2': '-0.181', 'Salivary duct cells': '10.9', 'Ductal cells': '0.521', 'Hepatocytes': '0.301', 'Cholangiocytes': '3.8', 'Proximal tubular cells': '0.033', 'Distal tubular cells': '6.1', 'Collecting duct cells': '13.6', 'Mesothelial cells': '0.352', 'Sertoli cells': '0.510', 'Granulosa cells': '7.5', 'Enteroendocrine cells': '3.6', 'Pancreatic endocrine cells': '10.2', 'Leydig cells': '0.629', 'Excitatory neurons': '4.1', 'Inhibitory neurons': '3.8', 'Cone photoreceptor cells': '8.5', 'Rod photoreceptor cells': '12.9', 'Bipolar cells': '9.5', 'Horizontal cells': '7.6', 'Astrocytes': '8.1', 'Oligodendrocyte precursor cells': '6.1', 'Oligodendrocytes': '6.9', 'Microglial cells': '7.2', 'Muller glia cells': '5.3', 'Schwann cells': '0.265', 'Spermatogonia': '0.561', 'Spermatocytes': '0.141', 'Early spermatids': '-0.484', 'Late spermatids': '-0.673', 'Oocytes': '8.8', 'Cytotrophoblasts': '3.6', 'Syncytiotrophoblasts': '3.8', 'Extravillous trophoblasts': '7.9', 'Endothelial cells': '13.3', 'Lymphatic endothelial cells': '21.4', 'Cardiomyocytes': '0.470', 'Skeletal myocytes': '-0.310', 'Smooth muscle cells': '14.3', 'Adipocytes': '15.4', 'Melanocytes': '0.148', 'Fibroblasts': '12.2', 'Peritubular cells': '0.636', 'Endometrial stromal cells': '14.5', 'Ovarian stromal cells': '11.5', 'Undifferentiated cells': '3.8', 'T-cells': '8.0', 'B-cells': '9.4', 'Plasma cells': '6.5', 'Nk-cells': '8.4', 'Granulocytes': '3.0', 'Monocytes': '6.5', 'Macrophages': '5.1', 'Hofbauer cells': '4.9', 'Kupffer cells': '5.3', 'Dendritic cells': '10.7', 'Langerhans cells': '0.310', 'Erythroid cells': '-0.011', 'Adipocytes (Subcutaneous)': '-0.494', 'Adipocytes (Visceral)': '-0.384', 'Breast glandular cells (progenitors)': '0.512', 'Adipocytes (Breast)': '-0.547', 'Colon enterocytes': '-0.173', 'Colon enteroendocrine cells': '0.261', 'Enteric glia cells': '0.376', 'Mitotic cells (Colon)': '-0.152', 'Mitotic cells (Heart)': '0.544', 'Podocytes': '-0.107', 'Ascending Loop of Henle cells': '0.445', 'Intercalated cells': '-0.071', 'Cholangiocyte': '0.386', 'NK-cells (Liver)': '-0.243', 'Respiratory ciliated cells': '0.303', 'Mitotic cells (Lung)': '0.072', 'NK-cells (Lung)': '0.070', 'B-cells (Lung)': '-0.014', 'Alpha cells': '0.468', 'Beta cells': '0.329', 'Prostate glandular cells': '-0.280', 'Prostate basal glandular cells': '0.290', 'Urothelial cells': '0.328', 'Keratinocyte (other)': '0.429', 'Keratinocyte (granular)': '-0.010', 'Hair cortex cells': '-0.153', 'Inner root sheath cells': '-0.099', 'Outer root sheath cells': '0.098', 'Sebaceous gland cells': '-0.052', 'Eccrine sweat gland cells': '-0.180', 'Adipocytes (Skin)': '-0.287', 'Mitotic cells (Skin)': '0.300', 'Parietal cells': '-0.590', 'Chief cells': '-0.506', 'Gastric mucous cells': '-0.327', 'Gastric enteroendocrine cells': '-0.333', 'Mitotic cells (Stomach)': '0.028', 'Parafollicular cells': '0.000', 'Thyroid glandular cells': '0.058', 'Mitotic cells (Thyroid)': '0.017', 'Adrenal cortex cells': '0.268', 'Adrenal medulla cells': '0.141', 'Mitotic cells (Adrenal gland)': '0.265', 'Minor salivary glandular cells': '0.109', 'Minor salivary 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P15731 | Q06224 | 32009536 | UbiBrowser | UBC4 | MSSSKRIAKELSDLERDPPTSCSAGPVGDDLYHWQASIMGPADSPYAGGVFFLSIHFPTDYPFKPPKISFTTKIYHPNINANGNICLDILKDQWSPALTLSKVLLSICSLLTDANPDDPLVPEIAHIYKTDRPKYEATAREWTKKYAV | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) | null | Not found | {} | 1QCQ, 5AIE, 8J1R | {} | YSH1 | MERTNTTTFKFFSLGGSNEVGRSCHILQYKGKTVMLDAGIHPAYQGLASLPFYDEFDLSKVDILLISHFHLDHAASLPYVMQRTNFQGRVFMTHPTKAIYRWLLRDFVRVTSIGSSSSSMGTKDEGLFSDEDLVDSFDKIETVDYHSTVDVNGIKFTAFHAGHVLGAAMFQIEIAGLRVLFTGDYSREVDRHLNSAEVPPLSSNVLIVESTFGTATHEPRLNRERKLTQLIHSTVMRGGRVLLPVFALGRAQEIMLILDEYWSQHADELGGGQVPIFYASNLAKKCMSVFQTYVNMMNDDIRKKFRDSQTNPFIFKNISYLRNLEDFQDFGPSVMLASPGMLQSGLSRDLLERWCPEDKNLVLITGYSIEGTMAKFIMLEPDTIPSINNPEITIPRRCQVEEISFAAHVDFQENLEFIEKISAPNIILVHGEANPMGRLKSALLSNFASLKGTDNEVHVFNPRNCVEVDLEFQGVKVAKAVGNIVNEIYKEENVEIKEEIAAKIEPIKEENEDNLDSQAEKGLVDEEEHKDIVVSGILVSDDKNFELDFLSLSDLREHHPDLSTTILRERQSVRVNCKKELIYWHILQMFGEAEVLQDDDRVTNQEPKVKEESKDNLTNTGKLILQIMGDIKLTIVNTLAVVEWTQDLMNDTVADSIIAILMNVDSAPASVKLSSHSCDDHDHNNVQSNAQGKIDEVERVKQISRLFKEQFGDCFTLFLNKDEYASNKEETITGVVTIGKSTAKIDFNNMKILECNSNPLKGRVESLLNIGGNLVTPLC | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) | Nucleus | Not found | {} | 6I1D | {} | [61.11, 85.51, 91.14, 93.22, 94.94, 96.2, 96.1, 94.44, 95.14, 95.11, 94.34, 93.91, 92.45, 90.9, 89.03, 90.68, 87.42, 81.19, 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P15918 | C9JYI4 | 19118899 | UbiBrowser | RAG1 | 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| Homo sapiens | Nucleus | Tissue enriched (lymphoid) | {'Ciliated cells': '0.4', 'Basal respiratory cells': '0.5', 'Club cells': '0.7', 'Ionocytes': '0.0', 'Mucus glandular cells': '1.2', 'Serous glandular cells': '0.2', 'Gastric mucus-secreting cells': '0.0', 'Proximal enterocytes': '3.1', 'Paneth cells': '1.6', 'Distal enterocytes': '1.3', 'Intestinal goblet cells': '0.9', 'Exocrine glandular cells': '-0.280', 'Basal prostatic cells': '0.5', 'Prostatic glandular cells': '0.7', 'Breast glandular cells': '0.213', 'Breast myoepithelial cells': '0.124', 'Glandular and luminal cells': '0.4', 'Secretory cells': '1.1', 'Basal keratinocytes': '0.2', 'Suprabasal keratinocytes': '0.2', 'Basal squamous epithelial cells': '0.2', 'Squamous epithelial cells': '0.1', 'Alveolar cells type 1': '0.237', 'Alveolar cells type 2': '-0.054', 'Salivary duct cells': '1.6', 'Ductal cells': '0.483', 'Hepatocytes': '0.459', 'Cholangiocytes': '0.0', 'Proximal tubular cells': '0.265', 'Distal tubular cells': '3.1', 'Collecting duct cells': '1.9', 'Mesothelial cells': '0.203', 'Sertoli cells': '0.384', 'Granulosa cells': '1.5', 'Enteroendocrine cells': '0.4', 'Pancreatic endocrine cells': '1.7', 'Leydig cells': '0.164', 'Excitatory neurons': '1.7', 'Inhibitory neurons': '1.7', 'Cone photoreceptor cells': '0.0', 'Rod photoreceptor cells': '1.0', 'Bipolar cells': '0.9', 'Horizontal cells': '0.6', 'Astrocytes': '0.0', 'Oligodendrocyte precursor cells': '0.9', 'Oligodendrocytes': '1.2', 'Microglial cells': '0.9', 'Muller glia cells': '0.3', 'Schwann cells': '0.108', 'Spermatogonia': '0.242', 'Spermatocytes': '0.124', 'Early spermatids': '-0.095', 'Late spermatids': '-0.269', 'Oocytes': '0.0', 'Cytotrophoblasts': '0.2', 'Syncytiotrophoblasts': '0.2', 'Extravillous trophoblasts': '0.2', 'Endothelial cells': '1.9', 'Lymphatic endothelial cells': '1.3', 'Cardiomyocytes': '0.472', 'Skeletal myocytes': '-0.156', 'Smooth muscle cells': '0.6', 'Adipocytes': '1.4', 'Melanocytes': '0.021', 'Fibroblasts': '1.2', 'Peritubular cells': '0.295', 'Endometrial stromal cells': '0.3', 'Ovarian stromal cells': '0.3', 'Undifferentiated cells': '0.6', 'T-cells': '0.4', 'B-cells': '0.1', 'Plasma cells': '0.1', 'Nk-cells': '1.2', 'Granulocytes': '0.0', 'Monocytes': '0.2', 'Macrophages': '0.3', 'Hofbauer cells': '0.4', 'Kupffer cells': '1.2', 'Dendritic cells': '1.6', 'Langerhans cells': '0.138', 'Erythroid cells': '0.028', 'Adipocytes (Subcutaneous)': '-0.012', 'Adipocytes (Visceral)': '-0.165', 'Breast glandular cells (progenitors)': '0.098', 'Adipocytes (Breast)': '-0.171', 'Colon enterocytes': '0.078', 'Colon enteroendocrine cells': '0.143', 'Enteric glia cells': '0.152', 'Mitotic cells (Colon)': '0.062', 'Mitotic cells (Heart)': '0.397', 'Podocytes': '-0.072', 'Ascending Loop of Henle cells': '0.493', 'Intercalated cells': '0.034', 'Cholangiocyte': '0.092', 'NK-cells (Liver)': '-0.014', 'Respiratory ciliated cells': '0.040', 'Mitotic cells (Lung)': '0.062', 'NK-cells (Lung)': '0.045', 'B-cells 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0.15, 0.29, 0.4, 0.0, 0.03, 0.11, 0.12, 0.0, 0.0, 0.33, 0.0, 0.0, 0.0, 0.22, 0.03, 0.02, 0.29, 0.48, 0.57, 0.36, 0.66, 0.16, 0.03, 0.5, 0.24, 0.01, 0.39, 0.68, 0.17, 0.56, 0.01, 0.33, 0.76, 0.22, 0.0, 0.55, 0.42, 0.02, 0.27, 0.85, 0.3, 0.9, 0.33, 0.74, 0.58, 0.0, 0.2, 0.5, 0.01, 0.0, 0.58, 0.38, 0.0, 0.2, 0.42, 0.16, 0.15, 0.73, 0.65, 0.34, 0.78, 1.0] | RING finger | Component of the RAG complex composed of core components RAG1 and RAG2, and associated component HMGB1 or HMGB2. | RAG | null | DCAF1,RAG1 , RAG2, HMGB1 or HMGB2, | H3 | mono | null | null | Homodimer | null | 81.264161 | 0.423183 | 84.346402 | 0.379055 | 1,451 |
P15918 | P04637 | 27249653 | DegPred | RAG1 | MAASFPPTLGLSSAPDEIQHPHIKFSEWKFKLFRVRSFEKTPEEAQKEKKDSFEGKPSLEQSPAVLDKADGQKPVPTQPLLKAHPKFSKKFHDNEKARGKAIHQANLRHLCRICGNSFRADEHNRRYPVHGPVDGKTLGLLRKKEKRATSWPDLIAKVFRIDVKADVDSIHPTEFCHNCWSIMHRKFSSAPCEVYFPRNVTMEWHPHTPSCDICNTARRGLKRKSLQPNLQLSKKLKTVLDQARQARQHKRRAQARISSKDVMKKIANCSKIHLSTKLLAVDFPEHFVKSISCQICEHILADPVETNCKHVFCRVCILRCLKVMGSYCPSCRYPCFPTDLESPVKSFLSVLNSLMVKCPAKECNEEVSLEKYNHHISSHKESKEIFVHINKGGRPRQHLLSLTRRAQKHRLRELKLQVKAFADKEEGGDVKSVCMTLFLLALRARNEHRQADELEAIMQGKGSGLQPAVCLAIRVNTFLSCSQYHKMYRTVKAITGRQIFQPLHALRNAEKVLLPGYHHFEWQPPLKNVSSSTDVGIIDGLSGLSSSVDDYPVDTIAKRFRYDSALVSALMDMEEDILEGMRSQDLDDYLNGPFTVVVKESCDGMGDVSEKHGSGPVVPEKAVRFSFTIMKITIAHSSQNVKVFEEAKPNSELCCKPLCLMLADESDHETLTAILSPLIAEREAMKSSELMLELGGILRTFKFIFRGTGYDEKLVREVEGLEASGSVYICTLCDATRLEASQNLVFHSITRSHAENLERYEVWRSNPYHESVEELRDRVKGVSAKPFIETVPSIDALHCDIGNAAEFYKIFQLEIGEVYKNPNASKEERKRWQATLDKHLRKKMNLKPIMRMNGNFARKLMTKETVDAVCELIPSEERHEALRELMDLYLKMKPVWRSSCPAKECPESLCQYSFNSQRFAELLSTKFKYRYEGKITNYFHKTLAHVPEIIERDGSIGAWASEGNESGNKLFRRFRKMNARQSKCYEMEDVLKHHWLYTSKYLQKFMNAHNALKTSGFTMNPQASLGDPLGIEDSLESQDSMEF | Homo sapiens | Nucleus | Tissue enriched (lymphoid) | {'Ciliated cells': '0.4', 'Basal respiratory cells': '0.5', 'Club cells': '0.7', 'Ionocytes': '0.0', 'Mucus glandular cells': '1.2', 'Serous glandular cells': '0.2', 'Gastric mucus-secreting cells': '0.0', 'Proximal enterocytes': '3.1', 'Paneth cells': '1.6', 'Distal enterocytes': '1.3', 'Intestinal goblet cells': '0.9', 'Exocrine glandular cells': '-0.280', 'Basal prostatic cells': '0.5', 'Prostatic glandular cells': '0.7', 'Breast glandular cells': '0.213', 'Breast myoepithelial cells': '0.124', 'Glandular and luminal cells': '0.4', 'Secretory cells': '1.1', 'Basal keratinocytes': '0.2', 'Suprabasal keratinocytes': '0.2', 'Basal squamous epithelial cells': '0.2', 'Squamous epithelial cells': '0.1', 'Alveolar cells type 1': '0.237', 'Alveolar cells type 2': '-0.054', 'Salivary duct cells': '1.6', 'Ductal cells': '0.483', 'Hepatocytes': '0.459', 'Cholangiocytes': '0.0', 'Proximal tubular cells': '0.265', 'Distal tubular cells': '3.1', 'Collecting duct cells': '1.9', 'Mesothelial cells': '0.203', 'Sertoli cells': '0.384', 'Granulosa cells': '1.5', 'Enteroendocrine cells': '0.4', 'Pancreatic endocrine cells': '1.7', 'Leydig cells': '0.164', 'Excitatory neurons': '1.7', 'Inhibitory neurons': '1.7', 'Cone photoreceptor cells': '0.0', 'Rod photoreceptor cells': '1.0', 'Bipolar cells': '0.9', 'Horizontal cells': '0.6', 'Astrocytes': '0.0', 'Oligodendrocyte precursor cells': '0.9', 'Oligodendrocytes': '1.2', 'Microglial cells': '0.9', 'Muller glia cells': '0.3', 'Schwann cells': '0.108', 'Spermatogonia': '0.242', 'Spermatocytes': '0.124', 'Early spermatids': '-0.095', 'Late spermatids': '-0.269', 'Oocytes': '0.0', 'Cytotrophoblasts': '0.2', 'Syncytiotrophoblasts': '0.2', 'Extravillous trophoblasts': '0.2', 'Endothelial cells': '1.9', 'Lymphatic endothelial cells': '1.3', 'Cardiomyocytes': '0.472', 'Skeletal myocytes': '-0.156', 'Smooth muscle cells': '0.6', 'Adipocytes': '1.4', 'Melanocytes': '0.021', 'Fibroblasts': '1.2', 'Peritubular cells': '0.295', 'Endometrial stromal cells': '0.3', 'Ovarian stromal cells': '0.3', 'Undifferentiated cells': '0.6', 'T-cells': '0.4', 'B-cells': '0.1', 'Plasma cells': '0.1', 'Nk-cells': '1.2', 'Granulocytes': '0.0', 'Monocytes': '0.2', 'Macrophages': '0.3', 'Hofbauer cells': '0.4', 'Kupffer cells': '1.2', 'Dendritic cells': '1.6', 'Langerhans cells': '0.138', 'Erythroid cells': '0.028', 'Adipocytes (Subcutaneous)': '-0.012', 'Adipocytes (Visceral)': '-0.165', 'Breast glandular cells (progenitors)': '0.098', 'Adipocytes (Breast)': '-0.171', 'Colon enterocytes': '0.078', 'Colon enteroendocrine cells': '0.143', 'Enteric glia cells': '0.152', 'Mitotic cells (Colon)': '0.062', 'Mitotic cells (Heart)': '0.397', 'Podocytes': '-0.072', 'Ascending Loop of Henle cells': '0.493', 'Intercalated cells': '0.034', 'Cholangiocyte': '0.092', 'NK-cells (Liver)': '-0.014', 'Respiratory ciliated cells': '0.040', 'Mitotic cells (Lung)': '0.062', 'NK-cells (Lung)': '0.045', 'B-cells (Lung)': '-0.132', 'Alpha cells': '0.314', 'Beta cells': '0.181', 'Prostate glandular cells': '-0.031', 'Prostate basal glandular cells': '0.313', 'Urothelial cells': '0.271', 'Keratinocyte (other)': '-0.231', 'Keratinocyte (granular)': '-0.135', 'Hair cortex cells': '0.246', 'Inner root sheath cells': '0.267', 'Outer root sheath cells': '0.338', 'Sebaceous gland cells': '0.259', 'Eccrine sweat gland cells': '0.376', 'Adipocytes (Skin)': '0.350', 'Mitotic cells (Skin)': '0.274', 'Parietal cells': '0.326', 'Chief cells': '0.192', 'Gastric mucous cells': '0.372', 'Gastric enteroendocrine cells': '0.286', 'Mitotic cells (Stomach)': '0.297', 'Parafollicular cells': '0.085', 'Thyroid glandular cells': '0.450', 'Mitotic cells (Thyroid)': '-0.059', 'Adrenal cortex cells': '0.592', 'Adrenal medulla cells': '-0.035', 'Mitotic cells (Adrenal gland)': '0.350', 'Minor salivary glandular cells': '0.608', 'Minor salivary gland ductal cells': '0.535', 'Minor salivary gland basal cells': '0.042', 'Mitotic cells (Minor salivary gland)': '0.035', 'Adipocytes (Minor salivary gland)': '0.177', 'Somatotropes': '0.024', 'Lactotropes': '-0.050', 'Gonadotropes': '0.102', 'Corticotropes': '-0.195', 'Thyrotropes': '0.165', 'Undifferentiated cells (Pituitary gland)': '0.287', 'Mitotic cells (Spleen)': '-0.234', 'Platelets': '-0.151', 'Erythrocytes': '-0.166', 'Hematopoietic stem cells': '-0.265', 'B-cells (Spleen)': '0.083', 'NK-cells (Spleen)': '0.264', 'Amygdala excitatory': '0.8', 'Cerebellar inhibitory': '0.6', 'Cge interneuron': '1.1', 'Deep-layer corticothalamic and 6b': '1.3', 'Deep-layer intratelencephalic': '1.5', 'Deep-layer near-projecting': '1.6', 'Eccentric medium spiny neuron': '0.5', 'Hippocampal ca1-3': '1.3', 'Hippocampal ca4': '0.3', 'Hippocampal dentate gyrus': '0.3', 'Lamp5-lhx6 and chandelier': '1.2', 'Lower rhombic lip': '2.9', 'Mammillary body': '2.6', 'Medium spiny neuron': '0.2', 'Mge interneuron': '1.8', 'Midbrain-derived inhibitory': '1.8', 'Miscellaneous': '1.1', 'Splatter': '2.1', 'Thalamic excitatory': '2.0', 'Upper rhombic lip': '0.4', 'Upper-layer intratelencephalic': '1.1', 'Astrocyte': '0.7', 'Bergmann glia': '1.4', 'Central nervous system macrophage': '1.5', 'Choroid plexus epithelial cell': '6.8', 'Committed oligodendrocyte precursor': '0.7', 'Ependymal cell': '0.5', 'Oligodendrocyte': '1.8', 'Oligodendrocyte precursor cell': '0.4', 'Endothelial cell': '6.8', 'Pericyte': '0.3', 'Vascular associated smooth muscle cell': '2.1', 'Fibroblast': '1.5', 'Leukocyte': '2.0', 'Basophil': '0.3', 'Eosinophil': '0.0', 'Neutrophil': '0.0', 'Classical monocyte': '0.0', 'Non-classical monocyte': '0.1', 'Intermediate monocyte': '0.0', 'T-reg': '0.1', 'GdT-cell': '0.0', 'MAIT T-cell': '0.3', 'Memory CD4 T-cell': '0.0', 'Naive CD4 T-cell': '0.4', 'Memory CD8 T-cell': '0.1', 'Naive CD8 T-cell': '0.3', 'Memory B-cell': '0.0', 'Naive B-cell': '0.4', 'Plasmacytoid DC': '0.0', 'Myeloid DC': '0.0', 'NK-cell': '2.3', 'Total PBMC': '0.1', 'Vd2 gdTCR': '0.0', 'Memory CD4 T-cell Th1\\/Th17': '0.8', 'Memory CD4 T-cell Th17': '0.4', 'Memory CD4 T-cell Th2': '0.4', 'Non-Vd2 gdTCR': '0.0', 'Memory CD4 T-cell Th1': '0.6', 'Memory CD4 T-cell TFH': '0.3', 'Terminal effector memory CD4 T-cell': '0.3', 'Central memory CD8 T-cell': '0.3', 'Effector memory CD8 T-cell': '0.2', 'Terminal effector memory CD8 T-cell': '0.1', 'Non-switched memory B-cell': '0.1', 'Plasmablast': '0.0', 'Switched memory B-cell': '0.0', 'Exhausted memory B-cell': '0.6', 'Progenitor cell': '0.5', 'Memory T-reg': '0.1', 'Naive CD4 T-cell activated': '0.1', 'Naive CD8 T-cell activated': '0.1', 'Naive T-reg': '0.6'} | null | {'Adipose Tissue': 0.4057857641196013, 'Adrenal Gland': 0.8675186046511627, 'Bladder': 0.3579738095238095, 'Blood': 0.2379831011840688, 'Blood Vessel': 0.2933549932584269, 'Brain': 0.1101639227857683, 'Breast': 0.4449297167755991, 'Cervix Uteri': 0.3465005263157895, 'Colon': 0.3597065468549422, 'Esophagus': 0.2373859999999999, 'Fallopian Tube': 0.4340344444444444, 'Heart': 0.1957524343786295, 'Kidney': 0.6407348314606741, 'Liver': 0.2803746017699115, 'Lung': 0.4784568079584775, 'Muscle': 0.0852849676214196, 'Nerve': 0.2672600161550889, 'Ovary': 0.3940442222222222, 'Pancreas': 0.2423982621951219, 'Pituitary': 0.2461227561837455, 'Prostate': 0.3530606122448979, 'Salivary Gland': 0.6816697530864197, 'Skin': 0.2567115765616362, 'Small Intestine': 0.5665286096256684, 'Spleen': 2.1116, 'Stomach': 0.3458365459610028, 'Testis': 0.8320800554016621, 'Thyroid': 1.571570045941807, 'Uterus': 0.4048269718309859, 'Vagina': 0.316294358974359} | TP53 | MEEPQSDPSVEPPLSQETFSDLWKLLPENNVLSPLPSQAMDDLMLSPDDIEQWFTEDPGPDEAPRMPEAAPPVAPAPAAPTPAAPAPAPSWPLSSSVPSQKTYQGSYGFRLGFLHSGTAKSVTCTYSPALNKMFCQLAKTCPVQLWVDSTPPPGTRVRAMAIYKQSQHMTEVVRRCPHHERCSDSDGLAPPQHLIRVEGNLRVEYLDDRNTFRHSVVVPYEPPEVGSDCTTIHYNYMCNSSCMGGMNRRPILTIITLEDSSGNLLGRNSFEVRVCACPGRDRRTEEENLRKKGEPHHELPPGSTKRALPNNTSSSPQPKKKPLDGEYFTLQIRGRERFEMFRELNEALELKDAQAGKEPGGSRAHSSHLKSKKGQSTSRHKKLMFKTEGPDSD | Homo sapiens | Cytoplasm, Nucleus, Nucleus, PML body, Endoplasmic reticulum, Mitochondrion matrix, Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, Nucleus, Cytoplasm, Nucleus, Cytoplasm, Nucleus, Cytoplasm, Nucleus, Cytoplasm, Nucleus, Cytoplasm, Nucleus, Cytoplasm, Cytoplasm | Low tissue specificity | {'Ciliated cells': '9.7', 'Basal respiratory cells': '24.5', 'Club cells': '17.3', 'Ionocytes': '15.5', 'Mucus glandular cells': '17.4', 'Serous glandular cells': '17.1', 'Gastric mucus-secreting cells': '11.2', 'Proximal enterocytes': '10.3', 'Paneth cells': '26.0', 'Distal enterocytes': '18.1', 'Intestinal goblet cells': '35.3', 'Exocrine glandular cells': '-0.708', 'Basal prostatic cells': '22.3', 'Prostatic glandular cells': '18.3', 'Breast glandular cells': '0.568', 'Breast myoepithelial cells': '0.559', 'Glandular and luminal cells': '21.5', 'Secretory cells': '38.8', 'Basal keratinocytes': '34.6', 'Suprabasal keratinocytes': '32.5', 'Basal squamous epithelial cells': '31.0', 'Squamous epithelial cells': '34.2', 'Alveolar cells type 1': '-0.172', 'Alveolar cells type 2': '0.210', 'Salivary duct cells': '19.8', 'Ductal cells': '0.627', 'Hepatocytes': '0.473', 'Cholangiocytes': '24.8', 'Proximal tubular cells': '0.199', 'Distal tubular cells': '15.4', 'Collecting duct cells': '21.4', 'Mesothelial cells': '0.355', 'Sertoli cells': '0.685', 'Granulosa cells': '20.0', 'Enteroendocrine cells': '29.3', 'Pancreatic endocrine cells': '20.4', 'Leydig cells': '0.655', 'Excitatory neurons': '2.0', 'Inhibitory neurons': '3.0', 'Cone photoreceptor cells': '5.1', 'Rod photoreceptor cells': '7.6', 'Bipolar cells': '5.3', 'Horizontal cells': '2.5', 'Astrocytes': '15.5', 'Oligodendrocyte precursor cells': '8.5', 'Oligodendrocytes': '7.4', 'Microglial cells': '7.2', 'Muller glia cells': '9.8', 'Schwann cells': '0.115', 'Spermatogonia': '0.447', 'Spermatocytes': '0.010', 'Early spermatids': '-0.537', 'Late spermatids': '-0.647', 'Oocytes': '4.4', 'Cytotrophoblasts': '39.7', 'Syncytiotrophoblasts': '20.4', 'Extravillous trophoblasts': '40.6', 'Endothelial cells': '26.1', 'Lymphatic endothelial cells': '20.1', 'Cardiomyocytes': '0.292', 'Skeletal myocytes': '-0.271', 'Smooth muscle cells': '18.8', 'Adipocytes': '22.1', 'Melanocytes': '0.378', 'Fibroblasts': '15.8', 'Peritubular cells': '0.544', 'Endometrial stromal cells': '28.3', 'Ovarian stromal cells': '20.5', 'Undifferentiated cells': '65.7', 'T-cells': '20.5', 'B-cells': '28.3', 'Plasma cells': '12.2', 'Nk-cells': '24.3', 'Granulocytes': '15.2', 'Monocytes': '23.2', 'Macrophages': '22.3', 'Hofbauer cells': '25.4', 'Kupffer cells': '28.1', 'Dendritic cells': '37.3', 'Langerhans cells': '0.416', 'Erythroid cells': '-0.142', 'Adipocytes (Subcutaneous)': '-0.285', 'Adipocytes (Visceral)': '-0.318', 'Breast glandular cells (progenitors)': '0.579', 'Adipocytes (Breast)': '-0.562', 'Colon enterocytes': '0.130', 'Colon enteroendocrine cells': '0.043', 'Enteric glia cells': '-0.338', 'Mitotic cells (Colon)': '0.199', 'Mitotic cells (Heart)': '0.516', 'Podocytes': '-0.175', 'Ascending Loop of Henle cells': '0.423', 'Intercalated cells': '-0.083', 'Cholangiocyte': '0.275', 'NK-cells (Liver)': '-0.251', 'Respiratory ciliated cells': '-0.071', 'Mitotic cells (Lung)': '0.244', 'NK-cells (Lung)': '-0.182', 'B-cells (Lung)': '-0.197', 'Alpha cells': '0.374', 'Beta cells': '0.172', 'Prostate glandular cells': '0.093', 'Prostate basal glandular cells': '0.400', 'Urothelial cells': '0.283', 'Keratinocyte (other)': '0.597', 'Keratinocyte (granular)': '-0.067', 'Hair cortex cells': '-0.039', 'Inner root sheath cells': '-0.007', 'Outer root sheath cells': '0.116', 'Sebaceous gland cells': '0.053', 'Eccrine sweat gland cells': '-0.248', 'Adipocytes (Skin)': '-0.383', 'Mitotic cells (Skin)': '0.447', 'Parietal cells': '-0.422', 'Chief cells': '-0.314', 'Gastric mucous cells': '-0.080', 'Gastric enteroendocrine cells': '-0.187', 'Mitotic cells (Stomach)': '0.363', 'Parafollicular cells': '0.045', 'Thyroid glandular cells': '0.117', 'Mitotic cells (Thyroid)': '0.058', 'Adrenal cortex cells': '0.509', 'Adrenal medulla cells': '-0.014', 'Mitotic cells (Adrenal gland)': '0.423', 'Minor salivary glandular cells': '0.553', 'Minor salivary gland ductal cells': '-0.053', 'Minor salivary gland basal cells': '0.505', 'Mitotic cells (Minor salivary gland)': '0.616', 'Adipocytes (Minor salivary gland)': '0.268', 'Somatotropes': '-0.284', 'Lactotropes': '-0.362', 'Gonadotropes': '0.004', 'Corticotropes': '-0.175', 'Thyrotropes': '-0.048', 'Undifferentiated cells (Pituitary gland)': '0.537', 'Mitotic cells (Spleen)': '-0.087', 'Platelets': '0.030', 'Erythrocytes': '-0.192', 'Hematopoietic stem cells': '-0.087', 'B-cells (Spleen)': '0.501', 'NK-cells (Spleen)': '0.140', 'Amygdala excitatory': '3.7', 'Cerebellar inhibitory': '6.2', 'Cge interneuron': '5.2', 'Deep-layer corticothalamic and 6b': '3.9', 'Deep-layer intratelencephalic': '4.3', 'Deep-layer near-projecting': '3.7', 'Eccentric medium spiny neuron': '3.7', 'Hippocampal ca1-3': '5.1', 'Hippocampal ca4': '5.7', 'Hippocampal dentate gyrus': '3.9', 'Lamp5-lhx6 and chandelier': '6.2', 'Lower rhombic lip': '4.4', 'Mammillary body': '4.7', 'Medium spiny neuron': '3.4', 'Mge interneuron': '5.6', 'Midbrain-derived inhibitory': '3.2', 'Miscellaneous': '4.1', 'Splatter': '4.9', 'Thalamic excitatory': '4.3', 'Upper rhombic lip': '3.5', 'Upper-layer intratelencephalic': '3.3', 'Astrocyte': '44.6', 'Bergmann glia': '33.2', 'Central nervous system macrophage': '29.3', 'Choroid plexus epithelial cell': '15.7', 'Committed oligodendrocyte precursor': '19.1', 'Ependymal cell': '8.2', 'Oligodendrocyte': '14.6', 'Oligodendrocyte precursor cell': '13.8', 'Endothelial cell': '19.0', 'Pericyte': '18.3', 'Vascular associated smooth muscle cell': '13.0', 'Fibroblast': '21.1', 'Leukocyte': '28.2', 'Basophil': '11.5', 'Eosinophil': '3.4', 'Neutrophil': '7.2', 'Classical monocyte': '18.8', 'Non-classical monocyte': '38.8', 'Intermediate monocyte': '57.9', 'T-reg': '41.2', 'GdT-cell': '13.0', 'MAIT T-cell': '47.7', 'Memory CD4 T-cell': '13.4', 'Naive CD4 T-cell': '35.3', 'Memory CD8 T-cell': '14.6', 'Naive CD8 T-cell': '33.9', 'Memory B-cell': '21.7', 'Naive B-cell': '39.1', 'Plasmacytoid DC': '77.7', 'Myeloid DC': '108.7', 'NK-cell': '34.9', 'Total PBMC': '42.1', 'Vd2 gdTCR': '50.5', 'Memory CD4 T-cell Th1\\/Th17': '29.2', 'Memory CD4 T-cell Th17': '31.4', 'Memory CD4 T-cell Th2': '32.4', 'Non-Vd2 gdTCR': '44.9', 'Memory CD4 T-cell Th1': '33.4', 'Memory CD4 T-cell TFH': '41.7', 'Terminal effector memory CD4 T-cell': '37.7', 'Central memory CD8 T-cell': '50.6', 'Effector memory CD8 T-cell': '44.8', 'Terminal effector memory CD8 T-cell': '36.8', 'Non-switched memory B-cell': '67.9', 'Plasmablast': '55.7', 'Switched memory B-cell': '69.3', 'Exhausted memory B-cell': '61.4', 'Progenitor cell': '66.7', 'Memory T-reg': '44.7', 'Naive CD4 T-cell activated': '50.4', 'Naive CD8 T-cell activated': '57.4', 'Naive T-reg': '53.9'} | 1A1U, 1AIE, 1C26, 1DT7, 1GZH, 1H26, 1HS5, 1JSP, 1KZY, 1MA3, 1OLG, 1OLH, 1PES, 1PET, 1SAE, 1SAF, 1SAK, 1SAL, 1TSR, 1TUP, 1UOL, 1XQH, 1YC5, 1YCQ, 1YCR, 1YCS, 2AC0, 2ADY, 2AHI, 2ATA, 2B3G, 2BIM, 2BIN, 2BIO, 2BIP, 2BIQ, 2F1X, 2FEJ, 2FOJ, 2FOO, 2GS0, 2H1L, 2H2D, 2H2F, 2H4F, 2H4H, 2H4J, 2H59, 2J0Z, 2J10, 2J11, 2J1W, 2J1X, 2J1Y, 2J1Z, 2J20, 2J21, 2K8F, 2L14, 2LY4, 2MEJ, 2MWO, 2MWP, 2MWY, 2MZD, 2OCJ, 2PCX, 2RUK, 2VUK, 2WGX, 2X0U, 2X0V, 2X0W, 2XWR, 2YBG, 2YDR, 2Z5S, 2Z5T, 3D05, 3D06, 3D07, 3D08, 3D09, 3D0A, 3DAB, 3DAC, 3IGK, 3IGL, 3KMD, 3KZ8, 3LW1, 3OQ5, 3PDH, 3Q01, 3Q05, 3Q06, 3SAK, 3TG5, 3TS8, 3ZME, 4AGL, 4AGM, 4AGN, 4AGO, 4AGP, 4AGQ, 4BUZ, 4BV2, 4HFZ, 4HJE, 4IBQ, 4IBS, 4IBT, 4IBU, 4IBV, 4IBW, 4IBY, 4IBZ, 4IJT, 4KVP, 4LO9, 4LOE, 4LOF, 4MZI, 4MZR, 4QO1, 4RP6, 4RP7, 4X34, 4XR8, 4ZZJ, 5A7B, 5AB9, 5ABA, 5AOI, 5AOJ, 5AOK, 5AOL, 5AOM, 5BUA, 5ECG, 5G4M, 5G4N, 5G4O, 5HOU, 5HP0, 5HPD, 5LAP, 5LGY, 5MCT, 5MCU, 5MCV, 5MCW, 5MF7, 5MG7, 5MHC, 5MOC, 5O1A, 5O1B, 5O1C, 5O1D, 5O1E, 5O1F, 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components RAG1 and RAG2, and associated component HMGB1 or HMGB2. | RAG | null | DCAF1,RAG1 , RAG2, HMGB1 or HMGB2, | H3 | mono | null | null | Homodimer | null | 81.264161 | 0.423183 | 74.332875 | 0.582494 | 1,067 |
P15918 | P15918 | 14671314, E3NethUbiquitome | UbiNet, UbiBrowser, 31181401 | RAG1 | MAASFPPTLGLSSAPDEIQHPHIKFSEWKFKLFRVRSFEKTPEEAQKEKKDSFEGKPSLEQSPAVLDKADGQKPVPTQPLLKAHPKFSKKFHDNEKARGKAIHQANLRHLCRICGNSFRADEHNRRYPVHGPVDGKTLGLLRKKEKRATSWPDLIAKVFRIDVKADVDSIHPTEFCHNCWSIMHRKFSSAPCEVYFPRNVTMEWHPHTPSCDICNTARRGLKRKSLQPNLQLSKKLKTVLDQARQARQHKRRAQARISSKDVMKKIANCSKIHLSTKLLAVDFPEHFVKSISCQICEHILADPVETNCKHVFCRVCILRCLKVMGSYCPSCRYPCFPTDLESPVKSFLSVLNSLMVKCPAKECNEEVSLEKYNHHISSHKESKEIFVHINKGGRPRQHLLSLTRRAQKHRLRELKLQVKAFADKEEGGDVKSVCMTLFLLALRARNEHRQADELEAIMQGKGSGLQPAVCLAIRVNTFLSCSQYHKMYRTVKAITGRQIFQPLHALRNAEKVLLPGYHHFEWQPPLKNVSSSTDVGIIDGLSGLSSSVDDYPVDTIAKRFRYDSALVSALMDMEEDILEGMRSQDLDDYLNGPFTVVVKESCDGMGDVSEKHGSGPVVPEKAVRFSFTIMKITIAHSSQNVKVFEEAKPNSELCCKPLCLMLADESDHETLTAILSPLIAEREAMKSSELMLELGGILRTFKFIFRGTGYDEKLVREVEGLEASGSVYICTLCDATRLEASQNLVFHSITRSHAENLERYEVWRSNPYHESVEELRDRVKGVSAKPFIETVPSIDALHCDIGNAAEFYKIFQLEIGEVYKNPNASKEERKRWQATLDKHLRKKMNLKPIMRMNGNFARKLMTKETVDAVCELIPSEERHEALRELMDLYLKMKPVWRSSCPAKECPESLCQYSFNSQRFAELLSTKFKYRYEGKITNYFHKTLAHVPEIIERDGSIGAWASEGNESGNKLFRRFRKMNARQSKCYEMEDVLKHHWLYTSKYLQKFMNAHNALKTSGFTMNPQASLGDPLGIEDSLESQDSMEF | Homo sapiens | Nucleus | Tissue enriched (lymphoid) | {'Ciliated cells': '0.4', 'Basal respiratory cells': '0.5', 'Club cells': '0.7', 'Ionocytes': '0.0', 'Mucus glandular cells': '1.2', 'Serous glandular cells': '0.2', 'Gastric mucus-secreting cells': '0.0', 'Proximal enterocytes': '3.1', 'Paneth cells': '1.6', 'Distal enterocytes': '1.3', 'Intestinal goblet cells': '0.9', 'Exocrine glandular cells': '-0.280', 'Basal prostatic cells': '0.5', 'Prostatic glandular cells': '0.7', 'Breast glandular cells': '0.213', 'Breast myoepithelial cells': '0.124', 'Glandular and luminal cells': '0.4', 'Secretory cells': '1.1', 'Basal keratinocytes': '0.2', 'Suprabasal keratinocytes': '0.2', 'Basal squamous epithelial cells': '0.2', 'Squamous epithelial cells': '0.1', 'Alveolar cells type 1': '0.237', 'Alveolar cells type 2': '-0.054', 'Salivary duct cells': '1.6', 'Ductal cells': '0.483', 'Hepatocytes': '0.459', 'Cholangiocytes': '0.0', 'Proximal tubular cells': '0.265', 'Distal tubular cells': '3.1', 'Collecting duct cells': '1.9', 'Mesothelial cells': '0.203', 'Sertoli cells': '0.384', 'Granulosa cells': '1.5', 'Enteroendocrine cells': '0.4', 'Pancreatic endocrine cells': '1.7', 'Leydig cells': '0.164', 'Excitatory neurons': '1.7', 'Inhibitory neurons': '1.7', 'Cone photoreceptor cells': '0.0', 'Rod photoreceptor cells': '1.0', 'Bipolar cells': '0.9', 'Horizontal cells': '0.6', 'Astrocytes': '0.0', 'Oligodendrocyte precursor cells': '0.9', 'Oligodendrocytes': '1.2', 'Microglial cells': '0.9', 'Muller glia cells': '0.3', 'Schwann cells': '0.108', 'Spermatogonia': '0.242', 'Spermatocytes': '0.124', 'Early spermatids': '-0.095', 'Late spermatids': '-0.269', 'Oocytes': '0.0', 'Cytotrophoblasts': '0.2', 'Syncytiotrophoblasts': '0.2', 'Extravillous trophoblasts': '0.2', 'Endothelial cells': '1.9', 'Lymphatic endothelial cells': '1.3', 'Cardiomyocytes': '0.472', 'Skeletal myocytes': '-0.156', 'Smooth muscle cells': '0.6', 'Adipocytes': '1.4', 'Melanocytes': '0.021', 'Fibroblasts': '1.2', 'Peritubular cells': '0.295', 'Endometrial stromal cells': '0.3', 'Ovarian stromal cells': '0.3', 'Undifferentiated cells': '0.6', 'T-cells': '0.4', 'B-cells': '0.1', 'Plasma cells': '0.1', 'Nk-cells': '1.2', 'Granulocytes': '0.0', 'Monocytes': '0.2', 'Macrophages': '0.3', 'Hofbauer cells': '0.4', 'Kupffer cells': '1.2', 'Dendritic cells': '1.6', 'Langerhans cells': '0.138', 'Erythroid cells': '0.028', 'Adipocytes (Subcutaneous)': '-0.012', 'Adipocytes (Visceral)': '-0.165', 'Breast glandular cells (progenitors)': '0.098', 'Adipocytes (Breast)': '-0.171', 'Colon enterocytes': '0.078', 'Colon enteroendocrine cells': '0.143', 'Enteric glia cells': '0.152', 'Mitotic cells (Colon)': '0.062', 'Mitotic cells (Heart)': '0.397', 'Podocytes': '-0.072', 'Ascending Loop of Henle cells': '0.493', 'Intercalated cells': '0.034', 'Cholangiocyte': '0.092', 'NK-cells (Liver)': '-0.014', 'Respiratory ciliated cells': '0.040', 'Mitotic cells (Lung)': '0.062', 'NK-cells (Lung)': '0.045', 'B-cells (Lung)': '-0.132', 'Alpha cells': '0.314', 'Beta cells': '0.181', 'Prostate glandular cells': '-0.031', 'Prostate basal glandular cells': '0.313', 'Urothelial cells': '0.271', 'Keratinocyte (other)': '-0.231', 'Keratinocyte (granular)': '-0.135', 'Hair cortex cells': '0.246', 'Inner root sheath cells': '0.267', 'Outer root sheath cells': '0.338', 'Sebaceous gland cells': '0.259', 'Eccrine sweat gland cells': '0.376', 'Adipocytes (Skin)': '0.350', 'Mitotic cells (Skin)': '0.274', 'Parietal cells': '0.326', 'Chief cells': '0.192', 'Gastric mucous cells': '0.372', 'Gastric enteroendocrine cells': '0.286', 'Mitotic cells (Stomach)': '0.297', 'Parafollicular cells': '0.085', 'Thyroid glandular cells': '0.450', 'Mitotic cells (Thyroid)': '-0.059', 'Adrenal cortex cells': '0.592', 'Adrenal medulla cells': '-0.035', 'Mitotic cells (Adrenal gland)': '0.350', 'Minor salivary glandular cells': '0.608', 'Minor salivary gland ductal cells': '0.535', 'Minor salivary gland basal cells': '0.042', 'Mitotic cells (Minor salivary gland)': '0.035', 'Adipocytes (Minor salivary gland)': '0.177', 'Somatotropes': '0.024', 'Lactotropes': '-0.050', 'Gonadotropes': '0.102', 'Corticotropes': '-0.195', 'Thyrotropes': '0.165', 'Undifferentiated cells (Pituitary gland)': '0.287', 'Mitotic cells (Spleen)': '-0.234', 'Platelets': '-0.151', 'Erythrocytes': '-0.166', 'Hematopoietic stem cells': '-0.265', 'B-cells (Spleen)': '0.083', 'NK-cells (Spleen)': '0.264', 'Amygdala excitatory': '0.8', 'Cerebellar inhibitory': '0.6', 'Cge interneuron': '1.1', 'Deep-layer corticothalamic and 6b': '1.3', 'Deep-layer intratelencephalic': '1.5', 'Deep-layer near-projecting': '1.6', 'Eccentric medium spiny neuron': '0.5', 'Hippocampal ca1-3': '1.3', 'Hippocampal ca4': '0.3', 'Hippocampal dentate gyrus': '0.3', 'Lamp5-lhx6 and chandelier': '1.2', 'Lower rhombic lip': '2.9', 'Mammillary body': '2.6', 'Medium spiny neuron': '0.2', 'Mge interneuron': '1.8', 'Midbrain-derived inhibitory': '1.8', 'Miscellaneous': '1.1', 'Splatter': '2.1', 'Thalamic excitatory': '2.0', 'Upper rhombic lip': '0.4', 'Upper-layer intratelencephalic': '1.1', 'Astrocyte': '0.7', 'Bergmann glia': '1.4', 'Central nervous system macrophage': '1.5', 'Choroid plexus epithelial cell': '6.8', 'Committed oligodendrocyte precursor': '0.7', 'Ependymal cell': '0.5', 'Oligodendrocyte': '1.8', 'Oligodendrocyte precursor cell': '0.4', 'Endothelial cell': '6.8', 'Pericyte': '0.3', 'Vascular associated smooth muscle cell': '2.1', 'Fibroblast': '1.5', 'Leukocyte': '2.0', 'Basophil': '0.3', 'Eosinophil': '0.0', 'Neutrophil': '0.0', 'Classical monocyte': '0.0', 'Non-classical monocyte': '0.1', 'Intermediate monocyte': '0.0', 'T-reg': '0.1', 'GdT-cell': '0.0', 'MAIT T-cell': '0.3', 'Memory CD4 T-cell': '0.0', 'Naive CD4 T-cell': '0.4', 'Memory CD8 T-cell': '0.1', 'Naive CD8 T-cell': '0.3', 'Memory B-cell': '0.0', 'Naive B-cell': '0.4', 'Plasmacytoid DC': '0.0', 'Myeloid DC': '0.0', 'NK-cell': '2.3', 'Total PBMC': '0.1', 'Vd2 gdTCR': '0.0', 'Memory CD4 T-cell Th1\\/Th17': '0.8', 'Memory CD4 T-cell Th17': '0.4', 'Memory CD4 T-cell Th2': '0.4', 'Non-Vd2 gdTCR': '0.0', 'Memory CD4 T-cell Th1': '0.6', 'Memory CD4 T-cell TFH': '0.3', 'Terminal effector memory CD4 T-cell': '0.3', 'Central memory CD8 T-cell': '0.3', 'Effector memory CD8 T-cell': '0.2', 'Terminal effector memory CD8 T-cell': '0.1', 'Non-switched memory B-cell': '0.1', 'Plasmablast': '0.0', 'Switched memory B-cell': '0.0', 'Exhausted memory B-cell': '0.6', 'Progenitor cell': '0.5', 'Memory T-reg': '0.1', 'Naive CD4 T-cell activated': '0.1', 'Naive CD8 T-cell activated': '0.1', 'Naive T-reg': '0.6'} | null | {'Adipose Tissue': 0.4057857641196013, 'Adrenal Gland': 0.8675186046511627, 'Bladder': 0.3579738095238095, 'Blood': 0.2379831011840688, 'Blood Vessel': 0.2933549932584269, 'Brain': 0.1101639227857683, 'Breast': 0.4449297167755991, 'Cervix Uteri': 0.3465005263157895, 'Colon': 0.3597065468549422, 'Esophagus': 0.2373859999999999, 'Fallopian Tube': 0.4340344444444444, 'Heart': 0.1957524343786295, 'Kidney': 0.6407348314606741, 'Liver': 0.2803746017699115, 'Lung': 0.4784568079584775, 'Muscle': 0.0852849676214196, 'Nerve': 0.2672600161550889, 'Ovary': 0.3940442222222222, 'Pancreas': 0.2423982621951219, 'Pituitary': 0.2461227561837455, 'Prostate': 0.3530606122448979, 'Salivary Gland': 0.6816697530864197, 'Skin': 0.2567115765616362, 'Small Intestine': 0.5665286096256684, 'Spleen': 2.1116, 'Stomach': 0.3458365459610028, 'Testis': 0.8320800554016621, 'Thyroid': 1.571570045941807, 'Uterus': 0.4048269718309859, 'Vagina': 0.316294358974359} | RAG1 | MAASFPPTLGLSSAPDEIQHPHIKFSEWKFKLFRVRSFEKTPEEAQKEKKDSFEGKPSLEQSPAVLDKADGQKPVPTQPLLKAHPKFSKKFHDNEKARGKAIHQANLRHLCRICGNSFRADEHNRRYPVHGPVDGKTLGLLRKKEKRATSWPDLIAKVFRIDVKADVDSIHPTEFCHNCWSIMHRKFSSAPCEVYFPRNVTMEWHPHTPSCDICNTARRGLKRKSLQPNLQLSKKLKTVLDQARQARQHKRRAQARISSKDVMKKIANCSKIHLSTKLLAVDFPEHFVKSISCQICEHILADPVETNCKHVFCRVCILRCLKVMGSYCPSCRYPCFPTDLESPVKSFLSVLNSLMVKCPAKECNEEVSLEKYNHHISSHKESKEIFVHINKGGRPRQHLLSLTRRAQKHRLRELKLQVKAFADKEEGGDVKSVCMTLFLLALRARNEHRQADELEAIMQGKGSGLQPAVCLAIRVNTFLSCSQYHKMYRTVKAITGRQIFQPLHALRNAEKVLLPGYHHFEWQPPLKNVSSSTDVGIIDGLSGLSSSVDDYPVDTIAKRFRYDSALVSALMDMEEDILEGMRSQDLDDYLNGPFTVVVKESCDGMGDVSEKHGSGPVVPEKAVRFSFTIMKITIAHSSQNVKVFEEAKPNSELCCKPLCLMLADESDHETLTAILSPLIAEREAMKSSELMLELGGILRTFKFIFRGTGYDEKLVREVEGLEASGSVYICTLCDATRLEASQNLVFHSITRSHAENLERYEVWRSNPYHESVEELRDRVKGVSAKPFIETVPSIDALHCDIGNAAEFYKIFQLEIGEVYKNPNASKEERKRWQATLDKHLRKKMNLKPIMRMNGNFARKLMTKETVDAVCELIPSEERHEALRELMDLYLKMKPVWRSSCPAKECPESLCQYSFNSQRFAELLSTKFKYRYEGKITNYFHKTLAHVPEIIERDGSIGAWASEGNESGNKLFRRFRKMNARQSKCYEMEDVLKHHWLYTSKYLQKFMNAHNALKTSGFTMNPQASLGDPLGIEDSLESQDSMEF | Homo sapiens | Nucleus | Tissue enriched (lymphoid) | {'Ciliated cells': '0.4', 'Basal respiratory cells': '0.5', 'Club cells': '0.7', 'Ionocytes': '0.0', 'Mucus glandular cells': '1.2', 'Serous glandular cells': '0.2', 'Gastric mucus-secreting cells': '0.0', 'Proximal enterocytes': '3.1', 'Paneth cells': '1.6', 'Distal enterocytes': '1.3', 'Intestinal goblet cells': '0.9', 'Exocrine glandular cells': '-0.280', 'Basal prostatic cells': '0.5', 'Prostatic glandular cells': '0.7', 'Breast glandular cells': '0.213', 'Breast myoepithelial cells': '0.124', 'Glandular and luminal cells': '0.4', 'Secretory cells': '1.1', 'Basal keratinocytes': '0.2', 'Suprabasal keratinocytes': '0.2', 'Basal squamous epithelial cells': '0.2', 'Squamous epithelial cells': '0.1', 'Alveolar cells type 1': '0.237', 'Alveolar cells type 2': '-0.054', 'Salivary duct cells': '1.6', 'Ductal cells': '0.483', 'Hepatocytes': '0.459', 'Cholangiocytes': '0.0', 'Proximal tubular cells': '0.265', 'Distal tubular cells': '3.1', 'Collecting duct cells': '1.9', 'Mesothelial cells': '0.203', 'Sertoli cells': '0.384', 'Granulosa cells': '1.5', 'Enteroendocrine cells': '0.4', 'Pancreatic endocrine cells': '1.7', 'Leydig cells': '0.164', 'Excitatory neurons': '1.7', 'Inhibitory neurons': '1.7', 'Cone photoreceptor cells': '0.0', 'Rod photoreceptor cells': '1.0', 'Bipolar cells': '0.9', 'Horizontal cells': '0.6', 'Astrocytes': '0.0', 'Oligodendrocyte precursor cells': '0.9', 'Oligodendrocytes': '1.2', 'Microglial cells': '0.9', 'Muller glia cells': '0.3', 'Schwann cells': '0.108', 'Spermatogonia': '0.242', 'Spermatocytes': '0.124', 'Early spermatids': '-0.095', 'Late spermatids': '-0.269', 'Oocytes': '0.0', 'Cytotrophoblasts': '0.2', 'Syncytiotrophoblasts': '0.2', 'Extravillous trophoblasts': '0.2', 'Endothelial cells': '1.9', 'Lymphatic endothelial cells': '1.3', 'Cardiomyocytes': '0.472', 'Skeletal myocytes': '-0.156', 'Smooth muscle cells': '0.6', 'Adipocytes': '1.4', 'Melanocytes': '0.021', 'Fibroblasts': '1.2', 'Peritubular cells': '0.295', 'Endometrial stromal cells': '0.3', 'Ovarian stromal cells': '0.3', 'Undifferentiated cells': '0.6', 'T-cells': '0.4', 'B-cells': '0.1', 'Plasma cells': '0.1', 'Nk-cells': '1.2', 'Granulocytes': '0.0', 'Monocytes': '0.2', 'Macrophages': '0.3', 'Hofbauer cells': '0.4', 'Kupffer cells': '1.2', 'Dendritic cells': '1.6', 'Langerhans cells': '0.138', 'Erythroid cells': '0.028', 'Adipocytes (Subcutaneous)': '-0.012', 'Adipocytes (Visceral)': '-0.165', 'Breast glandular cells (progenitors)': '0.098', 'Adipocytes (Breast)': '-0.171', 'Colon enterocytes': '0.078', 'Colon enteroendocrine cells': '0.143', 'Enteric glia cells': '0.152', 'Mitotic cells (Colon)': '0.062', 'Mitotic cells (Heart)': '0.397', 'Podocytes': '-0.072', 'Ascending Loop of Henle cells': '0.493', 'Intercalated cells': '0.034', 'Cholangiocyte': '0.092', 'NK-cells (Liver)': '-0.014', 'Respiratory ciliated cells': '0.040', 'Mitotic cells (Lung)': '0.062', 'NK-cells (Lung)': '0.045', 'B-cells (Lung)': '-0.132', 'Alpha cells': '0.314', 'Beta cells': '0.181', 'Prostate glandular cells': '-0.031', 'Prostate basal glandular cells': '0.313', 'Urothelial cells': '0.271', 'Keratinocyte (other)': '-0.231', 'Keratinocyte (granular)': '-0.135', 'Hair cortex cells': '0.246', 'Inner root sheath cells': '0.267', 'Outer root sheath cells': '0.338', 'Sebaceous gland cells': '0.259', 'Eccrine sweat gland cells': '0.376', 'Adipocytes (Skin)': '0.350', 'Mitotic cells (Skin)': '0.274', 'Parietal cells': '0.326', 'Chief cells': '0.192', 'Gastric mucous cells': '0.372', 'Gastric enteroendocrine cells': '0.286', 'Mitotic cells (Stomach)': '0.297', 'Parafollicular cells': '0.085', 'Thyroid glandular cells': '0.450', 'Mitotic cells (Thyroid)': '-0.059', 'Adrenal cortex cells': '0.592', 'Adrenal medulla cells': '-0.035', 'Mitotic cells (Adrenal gland)': '0.350', 'Minor salivary glandular cells': '0.608', 'Minor salivary gland ductal cells': '0.535', 'Minor salivary gland basal cells': '0.042', 'Mitotic cells (Minor salivary gland)': '0.035', 'Adipocytes (Minor salivary gland)': '0.177', 'Somatotropes': '0.024', 'Lactotropes': '-0.050', 'Gonadotropes': '0.102', 'Corticotropes': '-0.195', 'Thyrotropes': '0.165', 'Undifferentiated cells (Pituitary gland)': '0.287', 'Mitotic cells (Spleen)': '-0.234', 'Platelets': '-0.151', 'Erythrocytes': '-0.166', 'Hematopoietic stem cells': '-0.265', 'B-cells (Spleen)': '0.083', 'NK-cells (Spleen)': '0.264', 'Amygdala excitatory': '0.8', 'Cerebellar inhibitory': '0.6', 'Cge interneuron': '1.1', 'Deep-layer corticothalamic and 6b': '1.3', 'Deep-layer intratelencephalic': '1.5', 'Deep-layer near-projecting': '1.6', 'Eccentric medium spiny neuron': '0.5', 'Hippocampal ca1-3': '1.3', 'Hippocampal ca4': '0.3', 'Hippocampal dentate gyrus': '0.3', 'Lamp5-lhx6 and chandelier': '1.2', 'Lower rhombic lip': '2.9', 'Mammillary body': '2.6', 'Medium spiny neuron': '0.2', 'Mge interneuron': '1.8', 'Midbrain-derived inhibitory': '1.8', 'Miscellaneous': '1.1', 'Splatter': '2.1', 'Thalamic excitatory': '2.0', 'Upper rhombic lip': '0.4', 'Upper-layer intratelencephalic': '1.1', 'Astrocyte': '0.7', 'Bergmann glia': '1.4', 'Central nervous system macrophage': '1.5', 'Choroid plexus epithelial cell': '6.8', 'Committed oligodendrocyte precursor': '0.7', 'Ependymal cell': '0.5', 'Oligodendrocyte': '1.8', 'Oligodendrocyte precursor cell': '0.4', 'Endothelial cell': '6.8', 'Pericyte': '0.3', 'Vascular associated smooth muscle cell': '2.1', 'Fibroblast': '1.5', 'Leukocyte': '2.0', 'Basophil': '0.3', 'Eosinophil': '0.0', 'Neutrophil': '0.0', 'Classical monocyte': '0.0', 'Non-classical monocyte': '0.1', 'Intermediate monocyte': '0.0', 'T-reg': '0.1', 'GdT-cell': '0.0', 'MAIT T-cell': '0.3', 'Memory CD4 T-cell': '0.0', 'Naive CD4 T-cell': '0.4', 'Memory CD8 T-cell': '0.1', 'Naive CD8 T-cell': '0.3', 'Memory B-cell': '0.0', 'Naive B-cell': '0.4', 'Plasmacytoid DC': '0.0', 'Myeloid DC': '0.0', 'NK-cell': '2.3', 'Total PBMC': '0.1', 'Vd2 gdTCR': 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0.78, 0.82, 0.85, 0.67, 0.92, 0.9, 0.86, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 0.95, 1.0, 0.95, 0.95, 0.98, 0.9, 0.98, 0.83, 0.78, 0.79] | RING finger | Component of the RAG complex composed of core components RAG1 and RAG2, and associated component HMGB1 or HMGB2. | RAG | null | DCAF1,RAG1 , RAG2, HMGB1 or HMGB2, | H3 | mono | null | null | Homodimer | null | 81.264161 | 0.423183 | 81.264161 | 0.423183 | 472 |
P15918 | P52292 | 19118899 | UbiBrowser | RAG1 | MAASFPPTLGLSSAPDEIQHPHIKFSEWKFKLFRVRSFEKTPEEAQKEKKDSFEGKPSLEQSPAVLDKADGQKPVPTQPLLKAHPKFSKKFHDNEKARGKAIHQANLRHLCRICGNSFRADEHNRRYPVHGPVDGKTLGLLRKKEKRATSWPDLIAKVFRIDVKADVDSIHPTEFCHNCWSIMHRKFSSAPCEVYFPRNVTMEWHPHTPSCDICNTARRGLKRKSLQPNLQLSKKLKTVLDQARQARQHKRRAQARISSKDVMKKIANCSKIHLSTKLLAVDFPEHFVKSISCQICEHILADPVETNCKHVFCRVCILRCLKVMGSYCPSCRYPCFPTDLESPVKSFLSVLNSLMVKCPAKECNEEVSLEKYNHHISSHKESKEIFVHINKGGRPRQHLLSLTRRAQKHRLRELKLQVKAFADKEEGGDVKSVCMTLFLLALRARNEHRQADELEAIMQGKGSGLQPAVCLAIRVNTFLSCSQYHKMYRTVKAITGRQIFQPLHALRNAEKVLLPGYHHFEWQPPLKNVSSSTDVGIIDGLSGLSSSVDDYPVDTIAKRFRYDSALVSALMDMEEDILEGMRSQDLDDYLNGPFTVVVKESCDGMGDVSEKHGSGPVVPEKAVRFSFTIMKITIAHSSQNVKVFEEAKPNSELCCKPLCLMLADESDHETLTAILSPLIAEREAMKSSELMLELGGILRTFKFIFRGTGYDEKLVREVEGLEASGSVYICTLCDATRLEASQNLVFHSITRSHAENLERYEVWRSNPYHESVEELRDRVKGVSAKPFIETVPSIDALHCDIGNAAEFYKIFQLEIGEVYKNPNASKEERKRWQATLDKHLRKKMNLKPIMRMNGNFARKLMTKETVDAVCELIPSEERHEALRELMDLYLKMKPVWRSSCPAKECPESLCQYSFNSQRFAELLSTKFKYRYEGKITNYFHKTLAHVPEIIERDGSIGAWASEGNESGNKLFRRFRKMNARQSKCYEMEDVLKHHWLYTSKYLQKFMNAHNALKTSGFTMNPQASLGDPLGIEDSLESQDSMEF | Homo sapiens | Nucleus | Tissue enriched (lymphoid) | {'Ciliated cells': '0.4', 'Basal respiratory cells': '0.5', 'Club cells': '0.7', 'Ionocytes': '0.0', 'Mucus glandular cells': '1.2', 'Serous glandular cells': '0.2', 'Gastric mucus-secreting cells': '0.0', 'Proximal enterocytes': '3.1', 'Paneth cells': '1.6', 'Distal enterocytes': '1.3', 'Intestinal goblet cells': '0.9', 'Exocrine glandular cells': '-0.280', 'Basal prostatic cells': '0.5', 'Prostatic glandular cells': '0.7', 'Breast glandular cells': '0.213', 'Breast myoepithelial cells': '0.124', 'Glandular and luminal cells': '0.4', 'Secretory cells': '1.1', 'Basal keratinocytes': '0.2', 'Suprabasal keratinocytes': '0.2', 'Basal squamous epithelial cells': '0.2', 'Squamous epithelial cells': '0.1', 'Alveolar cells type 1': '0.237', 'Alveolar cells type 2': '-0.054', 'Salivary duct cells': '1.6', 'Ductal cells': '0.483', 'Hepatocytes': '0.459', 'Cholangiocytes': '0.0', 'Proximal tubular cells': '0.265', 'Distal tubular cells': '3.1', 'Collecting duct cells': '1.9', 'Mesothelial cells': '0.203', 'Sertoli cells': '0.384', 'Granulosa cells': '1.5', 'Enteroendocrine cells': '0.4', 'Pancreatic endocrine cells': '1.7', 'Leydig cells': '0.164', 'Excitatory neurons': '1.7', 'Inhibitory neurons': '1.7', 'Cone photoreceptor cells': '0.0', 'Rod photoreceptor cells': '1.0', 'Bipolar cells': '0.9', 'Horizontal cells': '0.6', 'Astrocytes': '0.0', 'Oligodendrocyte precursor cells': '0.9', 'Oligodendrocytes': '1.2', 'Microglial cells': '0.9', 'Muller glia cells': '0.3', 'Schwann cells': '0.108', 'Spermatogonia': '0.242', 'Spermatocytes': '0.124', 'Early spermatids': '-0.095', 'Late spermatids': '-0.269', 'Oocytes': '0.0', 'Cytotrophoblasts': '0.2', 'Syncytiotrophoblasts': '0.2', 'Extravillous trophoblasts': '0.2', 'Endothelial cells': '1.9', 'Lymphatic endothelial cells': '1.3', 'Cardiomyocytes': '0.472', 'Skeletal myocytes': '-0.156', 'Smooth muscle cells': '0.6', 'Adipocytes': '1.4', 'Melanocytes': '0.021', 'Fibroblasts': '1.2', 'Peritubular cells': '0.295', 'Endometrial stromal cells': '0.3', 'Ovarian stromal cells': '0.3', 'Undifferentiated cells': '0.6', 'T-cells': '0.4', 'B-cells': '0.1', 'Plasma cells': '0.1', 'Nk-cells': '1.2', 'Granulocytes': '0.0', 'Monocytes': '0.2', 'Macrophages': '0.3', 'Hofbauer cells': '0.4', 'Kupffer cells': '1.2', 'Dendritic cells': '1.6', 'Langerhans cells': '0.138', 'Erythroid cells': '0.028', 'Adipocytes (Subcutaneous)': '-0.012', 'Adipocytes (Visceral)': '-0.165', 'Breast glandular cells (progenitors)': '0.098', 'Adipocytes (Breast)': '-0.171', 'Colon enterocytes': '0.078', 'Colon enteroendocrine cells': '0.143', 'Enteric glia cells': '0.152', 'Mitotic cells (Colon)': '0.062', 'Mitotic cells (Heart)': '0.397', 'Podocytes': '-0.072', 'Ascending Loop of Henle cells': '0.493', 'Intercalated cells': '0.034', 'Cholangiocyte': '0.092', 'NK-cells (Liver)': '-0.014', 'Respiratory ciliated cells': '0.040', 'Mitotic cells (Lung)': '0.062', 'NK-cells (Lung)': '0.045', 'B-cells (Lung)': '-0.132', 'Alpha cells': '0.314', 'Beta cells': '0.181', 'Prostate glandular cells': '-0.031', 'Prostate basal glandular cells': '0.313', 'Urothelial cells': '0.271', 'Keratinocyte (other)': '-0.231', 'Keratinocyte (granular)': '-0.135', 'Hair cortex cells': '0.246', 'Inner root sheath cells': '0.267', 'Outer root sheath cells': '0.338', 'Sebaceous gland cells': '0.259', 'Eccrine sweat gland cells': '0.376', 'Adipocytes (Skin)': '0.350', 'Mitotic cells (Skin)': '0.274', 'Parietal cells': '0.326', 'Chief cells': '0.192', 'Gastric mucous cells': '0.372', 'Gastric enteroendocrine cells': '0.286', 'Mitotic cells (Stomach)': '0.297', 'Parafollicular cells': '0.085', 'Thyroid glandular cells': '0.450', 'Mitotic cells (Thyroid)': '-0.059', 'Adrenal cortex cells': '0.592', 'Adrenal medulla cells': '-0.035', 'Mitotic cells (Adrenal gland)': '0.350', 'Minor salivary glandular cells': '0.608', 'Minor salivary gland ductal cells': '0.535', 'Minor salivary gland basal cells': '0.042', 'Mitotic cells (Minor salivary gland)': '0.035', 'Adipocytes (Minor salivary gland)': '0.177', 'Somatotropes': '0.024', 'Lactotropes': '-0.050', 'Gonadotropes': '0.102', 'Corticotropes': '-0.195', 'Thyrotropes': '0.165', 'Undifferentiated cells (Pituitary gland)': '0.287', 'Mitotic cells (Spleen)': '-0.234', 'Platelets': '-0.151', 'Erythrocytes': '-0.166', 'Hematopoietic stem cells': '-0.265', 'B-cells (Spleen)': '0.083', 'NK-cells (Spleen)': '0.264', 'Amygdala excitatory': '0.8', 'Cerebellar inhibitory': '0.6', 'Cge interneuron': '1.1', 'Deep-layer corticothalamic and 6b': '1.3', 'Deep-layer intratelencephalic': '1.5', 'Deep-layer near-projecting': '1.6', 'Eccentric medium spiny neuron': '0.5', 'Hippocampal ca1-3': '1.3', 'Hippocampal ca4': '0.3', 'Hippocampal dentate gyrus': '0.3', 'Lamp5-lhx6 and chandelier': '1.2', 'Lower rhombic lip': '2.9', 'Mammillary body': '2.6', 'Medium spiny neuron': '0.2', 'Mge interneuron': '1.8', 'Midbrain-derived inhibitory': '1.8', 'Miscellaneous': '1.1', 'Splatter': '2.1', 'Thalamic excitatory': '2.0', 'Upper rhombic lip': '0.4', 'Upper-layer intratelencephalic': '1.1', 'Astrocyte': '0.7', 'Bergmann glia': '1.4', 'Central nervous system macrophage': '1.5', 'Choroid plexus epithelial cell': '6.8', 'Committed oligodendrocyte precursor': '0.7', 'Ependymal cell': '0.5', 'Oligodendrocyte': '1.8', 'Oligodendrocyte precursor cell': '0.4', 'Endothelial cell': '6.8', 'Pericyte': '0.3', 'Vascular associated smooth muscle cell': '2.1', 'Fibroblast': '1.5', 'Leukocyte': '2.0', 'Basophil': '0.3', 'Eosinophil': '0.0', 'Neutrophil': '0.0', 'Classical monocyte': '0.0', 'Non-classical monocyte': '0.1', 'Intermediate monocyte': '0.0', 'T-reg': '0.1', 'GdT-cell': '0.0', 'MAIT T-cell': '0.3', 'Memory CD4 T-cell': '0.0', 'Naive CD4 T-cell': '0.4', 'Memory CD8 T-cell': '0.1', 'Naive CD8 T-cell': '0.3', 'Memory B-cell': '0.0', 'Naive B-cell': '0.4', 'Plasmacytoid DC': '0.0', 'Myeloid DC': '0.0', 'NK-cell': '2.3', 'Total PBMC': '0.1', 'Vd2 gdTCR': '0.0', 'Memory CD4 T-cell Th1\\/Th17': '0.8', 'Memory CD4 T-cell Th17': '0.4', 'Memory CD4 T-cell Th2': '0.4', 'Non-Vd2 gdTCR': '0.0', 'Memory CD4 T-cell Th1': '0.6', 'Memory CD4 T-cell TFH': '0.3', 'Terminal effector memory CD4 T-cell': '0.3', 'Central memory CD8 T-cell': '0.3', 'Effector memory CD8 T-cell': '0.2', 'Terminal effector memory CD8 T-cell': '0.1', 'Non-switched memory B-cell': '0.1', 'Plasmablast': '0.0', 'Switched memory B-cell': '0.0', 'Exhausted memory B-cell': '0.6', 'Progenitor cell': '0.5', 'Memory T-reg': '0.1', 'Naive CD4 T-cell activated': '0.1', 'Naive CD8 T-cell activated': '0.1', 'Naive T-reg': '0.6'} | null | {'Adipose Tissue': 0.4057857641196013, 'Adrenal Gland': 0.8675186046511627, 'Bladder': 0.3579738095238095, 'Blood': 0.2379831011840688, 'Blood Vessel': 0.2933549932584269, 'Brain': 0.1101639227857683, 'Breast': 0.4449297167755991, 'Cervix Uteri': 0.3465005263157895, 'Colon': 0.3597065468549422, 'Esophagus': 0.2373859999999999, 'Fallopian Tube': 0.4340344444444444, 'Heart': 0.1957524343786295, 'Kidney': 0.6407348314606741, 'Liver': 0.2803746017699115, 'Lung': 0.4784568079584775, 'Muscle': 0.0852849676214196, 'Nerve': 0.2672600161550889, 'Ovary': 0.3940442222222222, 'Pancreas': 0.2423982621951219, 'Pituitary': 0.2461227561837455, 'Prostate': 0.3530606122448979, 'Salivary Gland': 0.6816697530864197, 'Skin': 0.2567115765616362, 'Small Intestine': 0.5665286096256684, 'Spleen': 2.1116, 'Stomach': 0.3458365459610028, 'Testis': 0.8320800554016621, 'Thyroid': 1.571570045941807, 'Uterus': 0.4048269718309859, 'Vagina': 0.316294358974359} | KPNA2 | MSTNENANTPAARLHRFKNKGKDSTEMRRRRIEVNVELRKAKKDDQMLKRRNVSSFPDDATSPLQENRNNQGTVNWSVDDIVKGINSSNVENQLQATQAARKLLSREKQPPIDNIIRAGLIPKFVSFLGRTDCSPIQFESAWALTNIASGTSEQTKAVVDGGAIPAFISLLASPHAHISEQAVWALGNIAGDGSVFRDLVIKYGAVDPLLALLAVPDMSSLACGYLRNLTWTLSNLCRNKNPAPPIDAVEQILPTLVRLLHHDDPEVLADTCWAISYLTDGPNERIGMVVKTGVVPQLVKLLGASELPIVTPALRAIGNIVTGTDEQTQVVIDAGALAVFPSLLTNPKTNIQKEATWTMSNITAGRQDQIQQVVNHGLVPFLVSVLSKADFKTQKEAVWAVTNYTSGGTVEQIVYLVHCGIIEPLMNLLTAKDTKIILVILDAISNIFQAAEKLGETEKLSIMIEECGGLDKIEALQNHENESVYKASLSLIEKYFSVEEEEDQNVVPETTSEGYTFQVQDGAPGTFNF | Homo sapiens | Cytoplasm, Nucleus, Endoplasmic reticulum membrane, Golgi apparatus membrane | Tissue enhanced (testis) | {'Ciliated cells': '35.0', 'Basal respiratory cells': '76.6', 'Club cells': '31.0', 'Ionocytes': '47.9', 'Mucus glandular cells': '23.7', 'Serous glandular cells': '20.1', 'Gastric mucus-secreting cells': '31.8', 'Proximal enterocytes': '14.7', 'Paneth cells': '16.2', 'Distal enterocytes': '27.1', 'Intestinal goblet cells': '31.0', 'Exocrine glandular cells': '-0.494', 'Basal prostatic cells': '8.2', 'Prostatic glandular cells': '6.2', 'Breast glandular cells': '-0.125', 'Breast myoepithelial cells': '-0.213', 'Glandular and luminal cells': '72.8', 'Secretory cells': '24.0', 'Basal keratinocytes': '92.7', 'Suprabasal keratinocytes': '69.0', 'Basal squamous epithelial cells': '50.1', 'Squamous epithelial cells': '58.5', 'Alveolar cells type 1': '-0.149', 'Alveolar cells type 2': '0.170', 'Salivary duct cells': '31.9', 'Ductal cells': '0.600', 'Hepatocytes': '0.405', 'Cholangiocytes': '5.7', 'Proximal tubular cells': '0.314', 'Distal tubular cells': '15.4', 'Collecting duct cells': '15.6', 'Mesothelial cells': '-0.268', 'Sertoli cells': '-0.376', 'Granulosa cells': '39.7', 'Enteroendocrine cells': '28.7', 'Pancreatic endocrine cells': '50.9', 'Leydig cells': '-0.378', 'Excitatory neurons': '8.2', 'Inhibitory neurons': '6.9', 'Cone photoreceptor cells': '45.9', 'Rod photoreceptor cells': '26.3', 'Bipolar cells': '25.2', 'Horizontal cells': '23.3', 'Astrocytes': '5.9', 'Oligodendrocyte precursor cells': '6.1', 'Oligodendrocytes': '5.6', 'Microglial cells': '3.6', 'Muller glia cells': '34.7', 'Schwann cells': '0.092', 'Spermatogonia': '-0.001', 'Spermatocytes': '0.393', 'Early spermatids': '0.874', 'Late spermatids': '0.507', 'Oocytes': '430.1', 'Cytotrophoblasts': '145.6', 'Syncytiotrophoblasts': '128.0', 'Extravillous trophoblasts': '315.9', 'Endothelial cells': '38.8', 'Lymphatic endothelial cells': '28.2', 'Cardiomyocytes': '0.380', 'Skeletal myocytes': '-0.257', 'Smooth muscle cells': '39.7', 'Adipocytes': '42.3', 'Melanocytes': '0.278', 'Fibroblasts': '44.3', 'Peritubular cells': '-0.312', 'Endometrial stromal cells': '66.7', 'Ovarian stromal cells': '8.4', 'Undifferentiated cells': '93.1', 'T-cells': '81.5', 'B-cells': '41.0', 'Plasma cells': '80.3', 'Nk-cells': '58.4', 'Granulocytes': '41.8', 'Monocytes': '87.6', 'Macrophages': '63.3', 'Hofbauer cells': '107.6', 'Kupffer cells': '32.5', 'Dendritic cells': '147.8', 'Langerhans cells': '0.008', 'Erythroid cells': '-0.088', 'Adipocytes (Subcutaneous)': '0.081', 'Adipocytes (Visceral)': '0.214', 'Breast glandular cells (progenitors)': '-0.183', 'Adipocytes (Breast)': '0.305', 'Colon enterocytes': '0.201', 'Colon enteroendocrine cells': '0.127', 'Enteric glia cells': '-0.318', 'Mitotic cells (Colon)': '0.217', 'Mitotic cells (Heart)': '0.455', 'Podocytes': '-0.150', 'Ascending Loop of Henle cells': '0.301', 'Intercalated cells': '-0.108', 'Cholangiocyte': '0.373', 'NK-cells (Liver)': '-0.354', 'Respiratory ciliated cells': '-0.148', 'Mitotic cells (Lung)': '0.372', 'NK-cells (Lung)': '-0.023', 'B-cells (Lung)': '-0.014', 'Alpha cells': '0.272', 'Beta cells': '0.156', 'Prostate glandular cells': '-0.177', 'Prostate basal glandular cells': '-0.022', 'Urothelial cells': '-0.036', 'Keratinocyte (other)': '-0.099', 'Keratinocyte (granular)': '-0.191', 'Hair cortex cells': '0.375', 'Inner root sheath cells': '0.473', 'Outer root sheath cells': '0.387', 'Sebaceous gland cells': '0.223', 'Eccrine sweat gland cells': '0.106', 'Adipocytes (Skin)': '0.083', 'Mitotic cells (Skin)': '0.469', 'Parietal cells': '-0.333', 'Chief cells': '-0.281', 'Gastric mucous cells': '0.131', 'Gastric enteroendocrine cells': '-0.205', 'Mitotic cells (Stomach)': '0.618', 'Parafollicular cells': '0.036', 'Thyroid glandular cells': '0.207', 'Mitotic cells (Thyroid)': '0.122', 'Adrenal cortex cells': '0.408', 'Adrenal medulla cells': '0.190', 'Mitotic cells (Adrenal gland)': '0.452', 'Minor salivary glandular cells': '0.313', 'Minor salivary gland ductal cells': '-0.314', 'Minor salivary gland basal cells': '0.642', 'Mitotic cells (Minor salivary gland)': '0.708', 'Adipocytes (Minor salivary gland)': '0.174', 'Somatotropes': '-0.149', 'Lactotropes': '-0.020', 'Gonadotropes': '0.128', 'Corticotropes': '0.123', 'Thyrotropes': '0.088', 'Undifferentiated cells (Pituitary gland)': '0.099', 'Mitotic cells (Spleen)': '0.697', 'Platelets': 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95.21, 95.47, 95.21, 95.63, 93.43, 95.98, 95.42, 96.2, 95.14, 95.32, 95.48, 95.25, 94.4, 94.14, 94.65, 92.97, 80.66, 60.11, 50.14, 39.98, 39.74, 36.65, 39.85, 47.94, 51.38, 53.09, 53.89, 53.58, 56.42, 54.57, 65.57, 65.81, 67.23, 63.49, 59.15, 56.06, 56.83, 58.31, 48.7, 51.9, 42.75, 46.46, 44.47, 42.45, 46.97, 43.46, 51.61, 54.56, 60.02] | [1.0, 0.99, 0.87, 0.89, 0.88, 0.77, 0.85, 0.75, 0.49, 0.71, 0.63, 0.46, 0.66, 0.76, 0.88, 0.87, 0.85, 0.92, 0.94, 0.96, 0.82, 0.53, 0.56, 0.32, 0.59, 0.33, 0.24, 0.17, 0.5, 0.61, 0.07, 0.58, 0.58, 0.26, 0.17, 0.38, 0.59, 0.57, 0.37, 0.73, 0.79, 0.7, 0.58, 0.83, 0.61, 0.71, 0.4, 0.34, 0.17, 0.32, 0.31, 0.35, 0.49, 0.18, 0.91, 0.68, 0.67, 0.76, 0.66, 0.18, 0.59, 0.07, 0.56, 0.35, 0.88, 0.32, 0.78, 0.87, 0.75, 0.91, 0.87, 0.71, 0.69, 0.68, 0.75, 0.29, 0.47, 0.2, 0.66, 0.38, 0.0, 0.24, 0.67, 0.09, 0.01, 0.57, 0.24, 0.92, 0.5, 0.34, 0.53, 0.39, 0.12, 0.17, 0.39, 0.0, 0.0, 0.24, 0.15, 0.0, 0.01, 0.3, 0.16, 0.0, 0.02, 0.37, 0.5, 0.88, 0.89, 0.14, 0.22, 0.05, 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0.19, 0.02, 0.18, 0.85, 0.35, 0.58, 0.01, 0.01, 0.57, 0.14, 0.0, 0.08, 0.72, 0.08, 0.02, 0.64, 0.28, 0.97, 0.48, 0.35, 0.64, 0.04, 0.05, 0.38, 0.01, 0.0, 0.0, 0.35, 0.0, 0.0, 0.0, 0.03, 0.0, 0.01, 0.33, 0.06, 0.3, 0.17, 0.64, 0.12, 0.0, 0.21, 0.36, 0.01, 0.08, 0.7, 0.25, 0.37, 0.01, 0.02, 0.63, 0.18, 0.0, 0.26, 0.56, 0.03, 0.02, 0.59, 0.26, 0.91, 0.57, 0.53, 0.68, 0.04, 0.16, 0.28, 0.16, 0.0, 0.0, 0.04, 0.01, 0.0, 0.0, 0.09, 0.01, 0.0, 0.12, 0.16, 0.33, 0.46, 0.47, 0.0, 0.0, 0.37, 0.34, 0.0, 0.17, 0.65, 0.37, 0.31, 0.0, 0.02, 0.45, 0.29, 0.05, 0.09, 0.44, 0.02, 0.01, 0.52, 0.88, 0.2, 0.38, 0.39, 0.58, 0.0, 0.13, 0.23, 0.12, 0.0, 0.0, 0.19, 0.0, 0.01, 0.06, 0.08, 0.01, 0.05, 0.28, 0.26, 0.22, 0.31, 0.23, 0.79, 0.04, 0.05, 0.32, 0.35, 0.04, 0.22, 0.72, 0.23, 0.41, 0.0, 0.09, 0.59, 0.08, 0.0, 0.0, 0.44, 0.1, 0.04, 0.67, 0.18, 0.94, 0.23, 0.28, 0.54, 0.05, 0.01, 0.34, 0.11, 0.0, 0.03, 0.36, 0.0, 0.02, 0.28, 0.09, 0.03, 0.01, 0.38, 0.05, 0.1, 0.4, 0.74, 0.52, 0.71, 0.45, 0.28, 0.75, 0.51, 0.07, 0.08, 0.44, 0.32, 0.01, 0.58, 0.75, 0.24, 0.15, 0.0, 0.15, 0.66, 0.23, 0.0, 0.44, 0.55, 0.06, 0.31, 0.83, 0.27, 0.97, 0.37, 0.6, 0.53, 0.0, 0.4, 0.58, 0.3, 0.0, 0.24, 0.5, 0.05, 0.12, 0.62, 0.72, 0.21, 0.19, 0.53, 0.83, 0.89, 0.83, 0.89, 0.76, 0.58, 0.77, 0.84, 0.74, 0.82, 0.24, 0.71, 0.7, 0.57, 1.0, 0.96, 0.43, 0.71, 0.51, 0.73, 0.85, 0.85, 0.92, 0.9, 0.9, 0.95, 0.97, 0.82, 0.96, 0.95, 0.99, 0.99] | RING finger | Component of the RAG complex composed of core components RAG1 and RAG2, and associated component HMGB1 or HMGB2. | RAG | null | DCAF1,RAG1 , RAG2, HMGB1 or HMGB2, | H3 | mono | null | null | Homodimer | null | 81.264161 | 0.423183 | 86.511493 | 0.33828 | 1,451 |
P15918 | P52294 | 19118899, E3NethUbiquitome | UbiNet, UbiBrowser, 31181401 | RAG1 | MAASFPPTLGLSSAPDEIQHPHIKFSEWKFKLFRVRSFEKTPEEAQKEKKDSFEGKPSLEQSPAVLDKADGQKPVPTQPLLKAHPKFSKKFHDNEKARGKAIHQANLRHLCRICGNSFRADEHNRRYPVHGPVDGKTLGLLRKKEKRATSWPDLIAKVFRIDVKADVDSIHPTEFCHNCWSIMHRKFSSAPCEVYFPRNVTMEWHPHTPSCDICNTARRGLKRKSLQPNLQLSKKLKTVLDQARQARQHKRRAQARISSKDVMKKIANCSKIHLSTKLLAVDFPEHFVKSISCQICEHILADPVETNCKHVFCRVCILRCLKVMGSYCPSCRYPCFPTDLESPVKSFLSVLNSLMVKCPAKECNEEVSLEKYNHHISSHKESKEIFVHINKGGRPRQHLLSLTRRAQKHRLRELKLQVKAFADKEEGGDVKSVCMTLFLLALRARNEHRQADELEAIMQGKGSGLQPAVCLAIRVNTFLSCSQYHKMYRTVKAITGRQIFQPLHALRNAEKVLLPGYHHFEWQPPLKNVSSSTDVGIIDGLSGLSSSVDDYPVDTIAKRFRYDSALVSALMDMEEDILEGMRSQDLDDYLNGPFTVVVKESCDGMGDVSEKHGSGPVVPEKAVRFSFTIMKITIAHSSQNVKVFEEAKPNSELCCKPLCLMLADESDHETLTAILSPLIAEREAMKSSELMLELGGILRTFKFIFRGTGYDEKLVREVEGLEASGSVYICTLCDATRLEASQNLVFHSITRSHAENLERYEVWRSNPYHESVEELRDRVKGVSAKPFIETVPSIDALHCDIGNAAEFYKIFQLEIGEVYKNPNASKEERKRWQATLDKHLRKKMNLKPIMRMNGNFARKLMTKETVDAVCELIPSEERHEALRELMDLYLKMKPVWRSSCPAKECPESLCQYSFNSQRFAELLSTKFKYRYEGKITNYFHKTLAHVPEIIERDGSIGAWASEGNESGNKLFRRFRKMNARQSKCYEMEDVLKHHWLYTSKYLQKFMNAHNALKTSGFTMNPQASLGDPLGIEDSLESQDSMEF | Homo sapiens | Nucleus | Tissue enriched (lymphoid) | {'Ciliated cells': '0.4', 'Basal respiratory cells': '0.5', 'Club cells': '0.7', 'Ionocytes': '0.0', 'Mucus glandular cells': '1.2', 'Serous glandular cells': '0.2', 'Gastric mucus-secreting cells': '0.0', 'Proximal enterocytes': '3.1', 'Paneth cells': '1.6', 'Distal enterocytes': '1.3', 'Intestinal goblet cells': '0.9', 'Exocrine glandular cells': '-0.280', 'Basal prostatic cells': '0.5', 'Prostatic glandular cells': '0.7', 'Breast glandular cells': '0.213', 'Breast myoepithelial cells': '0.124', 'Glandular and luminal cells': '0.4', 'Secretory cells': '1.1', 'Basal keratinocytes': '0.2', 'Suprabasal keratinocytes': '0.2', 'Basal squamous epithelial cells': '0.2', 'Squamous epithelial cells': '0.1', 'Alveolar cells type 1': '0.237', 'Alveolar cells type 2': '-0.054', 'Salivary duct cells': '1.6', 'Ductal cells': '0.483', 'Hepatocytes': '0.459', 'Cholangiocytes': '0.0', 'Proximal tubular cells': '0.265', 'Distal tubular cells': '3.1', 'Collecting duct cells': '1.9', 'Mesothelial cells': '0.203', 'Sertoli cells': '0.384', 'Granulosa cells': '1.5', 'Enteroendocrine cells': '0.4', 'Pancreatic endocrine cells': '1.7', 'Leydig cells': '0.164', 'Excitatory neurons': '1.7', 'Inhibitory neurons': '1.7', 'Cone photoreceptor cells': '0.0', 'Rod photoreceptor cells': '1.0', 'Bipolar cells': '0.9', 'Horizontal cells': '0.6', 'Astrocytes': '0.0', 'Oligodendrocyte precursor cells': '0.9', 'Oligodendrocytes': '1.2', 'Microglial cells': '0.9', 'Muller glia cells': '0.3', 'Schwann cells': '0.108', 'Spermatogonia': '0.242', 'Spermatocytes': '0.124', 'Early spermatids': '-0.095', 'Late spermatids': '-0.269', 'Oocytes': '0.0', 'Cytotrophoblasts': '0.2', 'Syncytiotrophoblasts': '0.2', 'Extravillous trophoblasts': '0.2', 'Endothelial cells': '1.9', 'Lymphatic endothelial cells': '1.3', 'Cardiomyocytes': '0.472', 'Skeletal myocytes': '-0.156', 'Smooth muscle cells': '0.6', 'Adipocytes': '1.4', 'Melanocytes': '0.021', 'Fibroblasts': '1.2', 'Peritubular cells': '0.295', 'Endometrial stromal cells': '0.3', 'Ovarian stromal cells': '0.3', 'Undifferentiated cells': '0.6', 'T-cells': '0.4', 'B-cells': '0.1', 'Plasma cells': '0.1', 'Nk-cells': '1.2', 'Granulocytes': '0.0', 'Monocytes': '0.2', 'Macrophages': '0.3', 'Hofbauer cells': '0.4', 'Kupffer cells': '1.2', 'Dendritic cells': '1.6', 'Langerhans cells': '0.138', 'Erythroid cells': '0.028', 'Adipocytes (Subcutaneous)': '-0.012', 'Adipocytes (Visceral)': '-0.165', 'Breast glandular cells (progenitors)': '0.098', 'Adipocytes (Breast)': '-0.171', 'Colon enterocytes': '0.078', 'Colon enteroendocrine cells': '0.143', 'Enteric glia cells': '0.152', 'Mitotic cells (Colon)': '0.062', 'Mitotic cells (Heart)': '0.397', 'Podocytes': '-0.072', 'Ascending Loop of Henle cells': '0.493', 'Intercalated cells': '0.034', 'Cholangiocyte': '0.092', 'NK-cells (Liver)': '-0.014', 'Respiratory ciliated cells': '0.040', 'Mitotic cells (Lung)': '0.062', 'NK-cells (Lung)': '0.045', 'B-cells (Lung)': '-0.132', 'Alpha cells': '0.314', 'Beta cells': '0.181', 'Prostate glandular cells': '-0.031', 'Prostate basal glandular cells': '0.313', 'Urothelial cells': '0.271', 'Keratinocyte (other)': '-0.231', 'Keratinocyte (granular)': '-0.135', 'Hair cortex cells': '0.246', 'Inner root sheath cells': '0.267', 'Outer root sheath cells': '0.338', 'Sebaceous gland cells': '0.259', 'Eccrine sweat gland cells': '0.376', 'Adipocytes (Skin)': '0.350', 'Mitotic cells (Skin)': '0.274', 'Parietal cells': '0.326', 'Chief cells': '0.192', 'Gastric mucous cells': '0.372', 'Gastric enteroendocrine cells': '0.286', 'Mitotic cells (Stomach)': '0.297', 'Parafollicular cells': '0.085', 'Thyroid glandular cells': '0.450', 'Mitotic cells (Thyroid)': '-0.059', 'Adrenal cortex cells': '0.592', 'Adrenal medulla cells': '-0.035', 'Mitotic cells (Adrenal gland)': '0.350', 'Minor salivary glandular cells': '0.608', 'Minor salivary gland ductal cells': '0.535', 'Minor salivary gland basal cells': '0.042', 'Mitotic cells (Minor salivary gland)': '0.035', 'Adipocytes (Minor salivary gland)': '0.177', 'Somatotropes': '0.024', 'Lactotropes': '-0.050', 'Gonadotropes': '0.102', 'Corticotropes': '-0.195', 'Thyrotropes': '0.165', 'Undifferentiated cells (Pituitary gland)': '0.287', 'Mitotic cells (Spleen)': '-0.234', 'Platelets': '-0.151', 'Erythrocytes': '-0.166', 'Hematopoietic stem cells': '-0.265', 'B-cells (Spleen)': '0.083', 'NK-cells (Spleen)': '0.264', 'Amygdala excitatory': '0.8', 'Cerebellar inhibitory': '0.6', 'Cge interneuron': '1.1', 'Deep-layer corticothalamic and 6b': '1.3', 'Deep-layer intratelencephalic': '1.5', 'Deep-layer near-projecting': '1.6', 'Eccentric medium spiny neuron': '0.5', 'Hippocampal ca1-3': '1.3', 'Hippocampal ca4': '0.3', 'Hippocampal dentate gyrus': '0.3', 'Lamp5-lhx6 and chandelier': '1.2', 'Lower rhombic lip': '2.9', 'Mammillary body': '2.6', 'Medium spiny neuron': '0.2', 'Mge interneuron': '1.8', 'Midbrain-derived inhibitory': '1.8', 'Miscellaneous': '1.1', 'Splatter': '2.1', 'Thalamic excitatory': '2.0', 'Upper rhombic lip': '0.4', 'Upper-layer intratelencephalic': '1.1', 'Astrocyte': '0.7', 'Bergmann glia': '1.4', 'Central nervous system macrophage': '1.5', 'Choroid plexus epithelial cell': '6.8', 'Committed oligodendrocyte precursor': '0.7', 'Ependymal cell': '0.5', 'Oligodendrocyte': '1.8', 'Oligodendrocyte precursor cell': '0.4', 'Endothelial cell': '6.8', 'Pericyte': '0.3', 'Vascular associated smooth muscle cell': '2.1', 'Fibroblast': '1.5', 'Leukocyte': '2.0', 'Basophil': '0.3', 'Eosinophil': '0.0', 'Neutrophil': '0.0', 'Classical monocyte': '0.0', 'Non-classical monocyte': '0.1', 'Intermediate monocyte': '0.0', 'T-reg': '0.1', 'GdT-cell': '0.0', 'MAIT T-cell': '0.3', 'Memory CD4 T-cell': '0.0', 'Naive CD4 T-cell': '0.4', 'Memory CD8 T-cell': '0.1', 'Naive CD8 T-cell': '0.3', 'Memory B-cell': '0.0', 'Naive B-cell': '0.4', 'Plasmacytoid DC': '0.0', 'Myeloid DC': '0.0', 'NK-cell': '2.3', 'Total PBMC': '0.1', 'Vd2 gdTCR': '0.0', 'Memory CD4 T-cell Th1\\/Th17': '0.8', 'Memory CD4 T-cell Th17': '0.4', 'Memory CD4 T-cell Th2': '0.4', 'Non-Vd2 gdTCR': '0.0', 'Memory CD4 T-cell Th1': '0.6', 'Memory CD4 T-cell TFH': '0.3', 'Terminal effector memory CD4 T-cell': '0.3', 'Central memory CD8 T-cell': '0.3', 'Effector memory CD8 T-cell': '0.2', 'Terminal effector memory CD8 T-cell': '0.1', 'Non-switched memory B-cell': '0.1', 'Plasmablast': '0.0', 'Switched memory B-cell': '0.0', 'Exhausted memory B-cell': '0.6', 'Progenitor cell': '0.5', 'Memory T-reg': '0.1', 'Naive CD4 T-cell activated': '0.1', 'Naive CD8 T-cell activated': '0.1', 'Naive T-reg': '0.6'} | null | {'Adipose Tissue': 0.4057857641196013, 'Adrenal Gland': 0.8675186046511627, 'Bladder': 0.3579738095238095, 'Blood': 0.2379831011840688, 'Blood Vessel': 0.2933549932584269, 'Brain': 0.1101639227857683, 'Breast': 0.4449297167755991, 'Cervix Uteri': 0.3465005263157895, 'Colon': 0.3597065468549422, 'Esophagus': 0.2373859999999999, 'Fallopian Tube': 0.4340344444444444, 'Heart': 0.1957524343786295, 'Kidney': 0.6407348314606741, 'Liver': 0.2803746017699115, 'Lung': 0.4784568079584775, 'Muscle': 0.0852849676214196, 'Nerve': 0.2672600161550889, 'Ovary': 0.3940442222222222, 'Pancreas': 0.2423982621951219, 'Pituitary': 0.2461227561837455, 'Prostate': 0.3530606122448979, 'Salivary Gland': 0.6816697530864197, 'Skin': 0.2567115765616362, 'Small Intestine': 0.5665286096256684, 'Spleen': 2.1116, 'Stomach': 0.3458365459610028, 'Testis': 0.8320800554016621, 'Thyroid': 1.571570045941807, 'Uterus': 0.4048269718309859, 'Vagina': 0.316294358974359} | KPNA1 | MTTPGKENFRLKSYKNKSLNPDEMRRRREEEGLQLRKQKREEQLFKRRNVATAEEETEEEVMSDGGFHEAQISNMEMAPGGVITSDMIEMIFSKSPEQQLSATQKFRKLLSKEPNPPIDEVISTPGVVARFVEFLKRKENCTLQFESAWVLTNIASGNSLQTRIVIQAGAVPIFIELLSSEFEDVQEQAVWALGNIAGDSTMCRDYVLDCNILPPLLQLFSKQNRLTMTRNAVWALSNLCRGKSPPPEFAKVSPCLNVLSWLLFVSDTDVLADACWALSYLSDGPNDKIQAVIDAGVCRRLVELLMHNDYKVVSPALRAVGNIVTGDDIQTQVILNCSALQSLLHLLSSPKESIKKEACWTISNITAGNRAQIQTVIDANIFPALISILQTAEFRTRKEAAWAITNATSGGSAEQIKYLVELGCIKPLCDLLTVMDSKIVQVALNGLENILRLGEQEAKRNGTGINPYCALIEEAYGLDKIEFLQSHENQEIYQKAFDLIEHYFGTEDEDSSIAPQVDLNQQQYIFQQCEAPMEGFQL | Homo sapiens | Cytoplasm, Nucleus | Low tissue specificity | {'Ciliated cells': '28.9', 'Basal respiratory cells': '15.0', 'Club cells': '17.9', 'Ionocytes': '17.3', 'Mucus glandular cells': '20.1', 'Serous glandular cells': '14.7', 'Gastric mucus-secreting cells': '19.5', 'Proximal enterocytes': '17.4', 'Paneth cells': '17.2', 'Distal enterocytes': '14.6', 'Intestinal goblet cells': '19.5', 'Exocrine glandular cells': '-0.621', 'Basal prostatic cells': '24.3', 'Prostatic glandular cells': '28.8', 'Breast glandular cells': '0.173', 'Breast myoepithelial cells': '0.107', 'Glandular and luminal cells': '24.1', 'Secretory cells': '18.9', 'Basal keratinocytes': '33.9', 'Suprabasal keratinocytes': '38.9', 'Basal squamous epithelial cells': '23.9', 'Squamous epithelial cells': '26.8', 'Alveolar cells type 1': '0.214', 'Alveolar cells type 2': '-0.264', 'Salivary duct cells': '18.8', 'Ductal cells': '0.604', 'Hepatocytes': '0.488', 'Cholangiocytes': '13.4', 'Proximal tubular cells': '0.158', 'Distal tubular cells': '24.6', 'Collecting duct cells': '19.4', 'Mesothelial cells': '0.048', 'Sertoli cells': '0.437', 'Granulosa cells': '8.0', 'Enteroendocrine cells': '19.4', 'Pancreatic endocrine cells': '22.1', 'Leydig cells': '0.428', 'Excitatory neurons': '103.6', 'Inhibitory neurons': '78.3', 'Cone photoreceptor cells': '32.3', 'Rod photoreceptor cells': '47.6', 'Bipolar cells': '30.1', 'Horizontal cells': '12.6', 'Astrocytes': '50.8', 'Oligodendrocyte precursor cells': '56.1', 'Oligodendrocytes': '85.4', 'Microglial cells': '59.0', 'Muller glia cells': '20.0', 'Schwann cells': '0.082', 'Spermatogonia': '0.458', 'Spermatocytes': '0.447', 'Early spermatids': '0.041', 'Late spermatids': '-0.431', 'Oocytes': '4.4', 'Cytotrophoblasts': '20.9', 'Syncytiotrophoblasts': '29.5', 'Extravillous trophoblasts': '26.6', 'Endothelial cells': '25.0', 'Lymphatic endothelial cells': '21.1', 'Cardiomyocytes': '0.631', 'Skeletal myocytes': '-0.224', 'Smooth muscle cells': '24.4', 'Adipocytes': '26.5', 'Melanocytes': '0.107', 'Fibroblasts': '23.5', 'Peritubular cells': '0.406', 'Endometrial stromal cells': '23.9', 'Ovarian stromal cells': '9.9', 'Undifferentiated cells': '11.0', 'T-cells': '30.3', 'B-cells': '30.7', 'Plasma cells': '27.8', 'Nk-cells': '33.7', 'Granulocytes': '32.9', 'Monocytes': '43.6', 'Macrophages': '29.2', 'Hofbauer cells': '21.3', 'Kupffer cells': '26.0', 'Dendritic cells': '28.9', 'Langerhans cells': '0.128', 'Erythroid cells': '-0.137', 'Adipocytes (Subcutaneous)': '0.179', 'Adipocytes (Visceral)': '-0.031', 'Breast glandular cells (progenitors)': '-0.002', 'Adipocytes (Breast)': '-0.030', 'Colon enterocytes': '-0.139', 'Colon enteroendocrine cells': '0.155', 'Enteric glia cells': '-0.224', 'Mitotic cells (Colon)': '-0.121', 'Mitotic cells (Heart)': '0.503', 'Podocytes': '-0.113', 'Ascending Loop of Henle cells': '0.382', 'Intercalated cells': '-0.084', 'Cholangiocyte': '0.233', 'NK-cells (Liver)': '-0.269', 'Respiratory ciliated cells': '0.030', 'Mitotic cells (Lung)': '-0.174', 'NK-cells (Lung)': '0.436', 'B-cells (Lung)': '0.181', 'Alpha cells': '0.414', 'Beta cells': '0.262', 'Prostate glandular cells': '-0.101', 'Prostate basal glandular cells': '0.162', 'Urothelial cells': '0.020', 'Keratinocyte (other)': '0.244', 'Keratinocyte (granular)': '-0.110', 'Hair cortex cells': '-0.067', 'Inner root sheath cells': '0.024', 'Outer root sheath cells': '0.063', 'Sebaceous gland cells': '0.043', 'Eccrine sweat gland cells': '-0.122', 'Adipocytes (Skin)': '-0.171', 'Mitotic cells (Skin)': '0.150', 'Parietal cells': '-0.631', 'Chief cells': '-0.554', 'Gastric mucous cells': '-0.416', 'Gastric enteroendocrine cells': '-0.432', 'Mitotic cells (Stomach)': '-0.012', 'Parafollicular cells': '0.096', 'Thyroid glandular cells': '0.232', 'Mitotic cells (Thyroid)': '-0.024', 'Adrenal cortex cells': '0.560', 'Adrenal medulla cells': '0.064', 'Mitotic cells (Adrenal gland)': '0.341', 'Minor salivary glandular cells': '0.393', 'Minor salivary gland ductal cells': '-0.048', 'Minor salivary gland basal cells': '0.465', 'Mitotic cells (Minor salivary gland)': '0.470', 'Adipocytes (Minor salivary gland)': '0.201', 'Somatotropes': '-0.081', 'Lactotropes': '-0.074', 'Gonadotropes': '0.024', 'Corticotropes': '-0.086', 'Thyrotropes': '-0.003', 'Undifferentiated cells (Pituitary gland)': '0.208', 'Mitotic cells (Spleen)': '-0.185', 'Platelets': '-0.099', 'Erythrocytes': '-0.063', 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0.78, 0.79, 0.93, 0.3, 0.18, 0.07, 0.54, 0.32, 0.0, 0.2, 0.74, 0.16, 0.81, 0.45, 0.0, 0.07, 0.46, 0.18, 0.0, 0.04, 0.49, 0.0, 0.01, 0.62, 0.21, 0.69, 0.84, 0.25, 0.17, 0.31, 0.0, 0.02, 0.18, 0.09, 0.0, 0.0, 0.12, 0.0, 0.0, 0.01, 0.05, 0.0, 0.0, 0.16, 0.24, 0.47, 0.35, 0.53, 0.06, 0.0, 0.37, 0.3, 0.0, 0.17, 0.76, 0.32, 0.35, 0.0, 0.0, 0.41, 0.1, 0.0, 0.09, 0.63, 0.06, 0.04, 0.64, 0.17, 0.95, 0.37, 0.35, 0.23, 0.01, 0.09, 0.17, 0.04, 0.0, 0.01, 0.07, 0.01, 0.02, 0.0, 0.0, 0.0, 0.04, 0.08, 0.09, 0.39, 0.26, 0.68, 0.0, 0.01, 0.28, 0.37, 0.0, 0.08, 0.61, 0.28, 0.61, 0.02, 0.07, 0.57, 0.16, 0.02, 0.17, 0.43, 0.04, 0.1, 0.8, 0.69, 0.14, 0.95, 0.39, 0.42, 0.3, 0.02, 0.16, 0.31, 0.11, 0.01, 0.0, 0.0, 0.02, 0.01, 0.0, 0.02, 0.01, 0.03, 0.09, 0.3, 0.33, 0.66, 0.58, 0.6, 0.08, 0.57, 0.21, 0.74, 0.3, 0.02, 0.3, 0.47, 0.0, 0.06, 0.72, 0.17, 0.0, 0.18, 0.59, 0.0, 0.0, 0.66, 0.22, 0.85, 0.16, 0.28, 0.28, 0.0, 0.02, 0.06, 0.0, 0.0, 0.0, 0.31, 0.0, 0.0, 0.02, 0.26, 0.02, 0.01, 0.37, 0.51, 0.52, 0.31, 0.69, 0.22, 0.0, 0.36, 0.25, 0.0, 0.13, 0.7, 0.18, 0.61, 0.01, 0.06, 0.67, 0.24, 0.0, 0.04, 0.42, 0.02, 0.01, 0.48, 0.3, 0.9, 0.33, 0.26, 0.55, 0.0, 0.01, 0.38, 0.0, 0.0, 0.01, 0.24, 0.01, 0.0, 0.0, 0.05, 0.0, 0.0, 0.28, 0.0, 0.31, 0.13, 0.72, 0.02, 0.0, 0.36, 0.32, 0.0, 0.12, 0.67, 0.27, 0.6, 0.0, 0.09, 0.59, 0.1, 0.0, 0.23, 0.58, 0.03, 0.04, 0.76, 0.07, 0.79, 0.45, 0.23, 0.6, 0.02, 0.19, 0.32, 0.18, 0.0, 0.0, 0.12, 0.0, 0.0, 0.07, 0.15, 0.0, 0.0, 0.37, 0.03, 0.19, 0.5, 0.58, 0.01, 0.01, 0.37, 0.31, 0.0, 0.12, 0.69, 0.08, 0.53, 0.0, 0.01, 0.35, 0.24, 0.0, 0.05, 0.44, 0.08, 0.01, 0.58, 0.78, 0.23, 0.62, 0.37, 0.72, 0.0, 0.19, 0.26, 0.13, 0.0, 0.0, 0.18, 0.0, 0.0, 0.05, 0.18, 0.01, 0.03, 0.61, 0.21, 0.14, 0.21, 0.37, 0.72, 0.06, 0.08, 0.4, 0.28, 0.01, 0.11, 0.66, 0.31, 0.42, 0.0, 0.05, 0.42, 0.01, 0.0, 0.0, 0.3, 0.0, 0.03, 0.7, 0.19, 0.91, 0.3, 0.25, 0.25, 0.03, 0.0, 0.16, 0.04, 0.01, 0.0, 0.37, 0.0, 0.0, 0.2, 0.13, 0.0, 0.0, 0.4, 0.05, 0.0, 0.28, 0.56, 0.15, 0.04, 0.67, 0.75, 0.7, 0.75, 0.53, 0.72, 0.72, 0.15, 0.47, 0.06, 0.1, 0.43, 0.37, 0.0, 0.49, 0.69, 0.05, 0.62, 0.0, 0.18, 0.52, 0.16, 0.0, 0.48, 0.73, 0.02, 0.32, 0.72, 0.25, 0.94, 0.31, 0.75, 0.62, 0.0, 0.39, 0.52, 0.26, 0.0, 0.4, 0.44, 0.03, 0.17, 0.65, 0.74, 0.2, 0.18, 0.48, 0.92, 0.92, 0.93, 0.83, 0.5, 0.79, 0.82, 0.76, 0.4, 0.32, 0.58, 0.54, 0.3, 0.84, 0.92, 0.68, 0.84, 0.62, 0.65, 0.45, 0.75, 0.79, 0.92, 0.86, 0.91, 0.76, 0.85, 0.93, 0.89, 0.79, 0.92, 0.94, 0.95] | RING finger | Component of the RAG complex composed of core components RAG1 and RAG2, and associated component HMGB1 or HMGB2. | RAG | null | DCAF1,RAG1 , RAG2, HMGB1 or HMGB2, | H3 | mono | null | null | Homodimer | null | 81.264161 | 0.423183 | 86.439201 | 0.334907 | 1,451 |
P15918 | Q16695 | 20122409 | UbiNet, UbiBrowser, 31181401 | RAG1 | MAASFPPTLGLSSAPDEIQHPHIKFSEWKFKLFRVRSFEKTPEEAQKEKKDSFEGKPSLEQSPAVLDKADGQKPVPTQPLLKAHPKFSKKFHDNEKARGKAIHQANLRHLCRICGNSFRADEHNRRYPVHGPVDGKTLGLLRKKEKRATSWPDLIAKVFRIDVKADVDSIHPTEFCHNCWSIMHRKFSSAPCEVYFPRNVTMEWHPHTPSCDICNTARRGLKRKSLQPNLQLSKKLKTVLDQARQARQHKRRAQARISSKDVMKKIANCSKIHLSTKLLAVDFPEHFVKSISCQICEHILADPVETNCKHVFCRVCILRCLKVMGSYCPSCRYPCFPTDLESPVKSFLSVLNSLMVKCPAKECNEEVSLEKYNHHISSHKESKEIFVHINKGGRPRQHLLSLTRRAQKHRLRELKLQVKAFADKEEGGDVKSVCMTLFLLALRARNEHRQADELEAIMQGKGSGLQPAVCLAIRVNTFLSCSQYHKMYRTVKAITGRQIFQPLHALRNAEKVLLPGYHHFEWQPPLKNVSSSTDVGIIDGLSGLSSSVDDYPVDTIAKRFRYDSALVSALMDMEEDILEGMRSQDLDDYLNGPFTVVVKESCDGMGDVSEKHGSGPVVPEKAVRFSFTIMKITIAHSSQNVKVFEEAKPNSELCCKPLCLMLADESDHETLTAILSPLIAEREAMKSSELMLELGGILRTFKFIFRGTGYDEKLVREVEGLEASGSVYICTLCDATRLEASQNLVFHSITRSHAENLERYEVWRSNPYHESVEELRDRVKGVSAKPFIETVPSIDALHCDIGNAAEFYKIFQLEIGEVYKNPNASKEERKRWQATLDKHLRKKMNLKPIMRMNGNFARKLMTKETVDAVCELIPSEERHEALRELMDLYLKMKPVWRSSCPAKECPESLCQYSFNSQRFAELLSTKFKYRYEGKITNYFHKTLAHVPEIIERDGSIGAWASEGNESGNKLFRRFRKMNARQSKCYEMEDVLKHHWLYTSKYLQKFMNAHNALKTSGFTMNPQASLGDPLGIEDSLESQDSMEF | Homo sapiens | Nucleus | Tissue enriched (lymphoid) | {'Ciliated cells': '0.4', 'Basal respiratory cells': '0.5', 'Club cells': '0.7', 'Ionocytes': '0.0', 'Mucus glandular cells': '1.2', 'Serous glandular cells': '0.2', 'Gastric mucus-secreting cells': '0.0', 'Proximal enterocytes': '3.1', 'Paneth cells': '1.6', 'Distal enterocytes': '1.3', 'Intestinal goblet cells': '0.9', 'Exocrine glandular cells': '-0.280', 'Basal prostatic cells': '0.5', 'Prostatic glandular cells': '0.7', 'Breast glandular cells': '0.213', 'Breast myoepithelial cells': '0.124', 'Glandular and luminal cells': '0.4', 'Secretory cells': '1.1', 'Basal keratinocytes': '0.2', 'Suprabasal keratinocytes': '0.2', 'Basal squamous epithelial cells': '0.2', 'Squamous epithelial cells': '0.1', 'Alveolar cells type 1': '0.237', 'Alveolar cells type 2': '-0.054', 'Salivary duct cells': '1.6', 'Ductal cells': '0.483', 'Hepatocytes': '0.459', 'Cholangiocytes': '0.0', 'Proximal tubular cells': '0.265', 'Distal tubular cells': '3.1', 'Collecting duct cells': '1.9', 'Mesothelial cells': '0.203', 'Sertoli cells': '0.384', 'Granulosa cells': '1.5', 'Enteroendocrine cells': '0.4', 'Pancreatic endocrine cells': '1.7', 'Leydig cells': '0.164', 'Excitatory neurons': '1.7', 'Inhibitory neurons': '1.7', 'Cone photoreceptor cells': '0.0', 'Rod photoreceptor cells': '1.0', 'Bipolar cells': '0.9', 'Horizontal cells': '0.6', 'Astrocytes': '0.0', 'Oligodendrocyte precursor cells': '0.9', 'Oligodendrocytes': '1.2', 'Microglial cells': '0.9', 'Muller glia cells': '0.3', 'Schwann cells': '0.108', 'Spermatogonia': '0.242', 'Spermatocytes': '0.124', 'Early spermatids': '-0.095', 'Late spermatids': '-0.269', 'Oocytes': '0.0', 'Cytotrophoblasts': '0.2', 'Syncytiotrophoblasts': '0.2', 'Extravillous trophoblasts': '0.2', 'Endothelial cells': '1.9', 'Lymphatic endothelial cells': '1.3', 'Cardiomyocytes': '0.472', 'Skeletal myocytes': '-0.156', 'Smooth muscle cells': '0.6', 'Adipocytes': '1.4', 'Melanocytes': '0.021', 'Fibroblasts': '1.2', 'Peritubular cells': '0.295', 'Endometrial stromal cells': '0.3', 'Ovarian stromal cells': '0.3', 'Undifferentiated cells': '0.6', 'T-cells': '0.4', 'B-cells': '0.1', 'Plasma cells': '0.1', 'Nk-cells': '1.2', 'Granulocytes': '0.0', 'Monocytes': '0.2', 'Macrophages': '0.3', 'Hofbauer cells': '0.4', 'Kupffer cells': '1.2', 'Dendritic cells': '1.6', 'Langerhans cells': '0.138', 'Erythroid cells': '0.028', 'Adipocytes (Subcutaneous)': '-0.012', 'Adipocytes (Visceral)': '-0.165', 'Breast glandular cells (progenitors)': '0.098', 'Adipocytes (Breast)': '-0.171', 'Colon enterocytes': '0.078', 'Colon enteroendocrine cells': '0.143', 'Enteric glia cells': '0.152', 'Mitotic cells (Colon)': '0.062', 'Mitotic cells (Heart)': '0.397', 'Podocytes': '-0.072', 'Ascending Loop of Henle cells': '0.493', 'Intercalated cells': '0.034', 'Cholangiocyte': '0.092', 'NK-cells (Liver)': '-0.014', 'Respiratory ciliated cells': '0.040', 'Mitotic cells (Lung)': '0.062', 'NK-cells (Lung)': '0.045', 'B-cells (Lung)': '-0.132', 'Alpha cells': '0.314', 'Beta cells': '0.181', 'Prostate glandular cells': '-0.031', 'Prostate basal glandular cells': '0.313', 'Urothelial cells': '0.271', 'Keratinocyte (other)': '-0.231', 'Keratinocyte (granular)': '-0.135', 'Hair cortex cells': '0.246', 'Inner root sheath cells': '0.267', 'Outer root sheath cells': '0.338', 'Sebaceous gland cells': '0.259', 'Eccrine sweat gland cells': '0.376', 'Adipocytes (Skin)': '0.350', 'Mitotic cells (Skin)': '0.274', 'Parietal cells': '0.326', 'Chief cells': '0.192', 'Gastric mucous cells': '0.372', 'Gastric enteroendocrine cells': '0.286', 'Mitotic cells (Stomach)': '0.297', 'Parafollicular cells': '0.085', 'Thyroid glandular cells': '0.450', 'Mitotic cells (Thyroid)': '-0.059', 'Adrenal cortex cells': '0.592', 'Adrenal medulla cells': '-0.035', 'Mitotic cells (Adrenal gland)': '0.350', 'Minor salivary glandular cells': '0.608', 'Minor salivary gland ductal cells': '0.535', 'Minor salivary gland basal cells': '0.042', 'Mitotic cells (Minor salivary gland)': '0.035', 'Adipocytes (Minor salivary gland)': '0.177', 'Somatotropes': '0.024', 'Lactotropes': '-0.050', 'Gonadotropes': '0.102', 'Corticotropes': '-0.195', 'Thyrotropes': '0.165', 'Undifferentiated cells (Pituitary gland)': '0.287', 'Mitotic cells (Spleen)': '-0.234', 'Platelets': '-0.151', 'Erythrocytes': '-0.166', 'Hematopoietic stem cells': '-0.265', 'B-cells (Spleen)': '0.083', 'NK-cells (Spleen)': '0.264', 'Amygdala excitatory': '0.8', 'Cerebellar inhibitory': '0.6', 'Cge interneuron': '1.1', 'Deep-layer corticothalamic and 6b': '1.3', 'Deep-layer intratelencephalic': '1.5', 'Deep-layer near-projecting': '1.6', 'Eccentric medium spiny neuron': '0.5', 'Hippocampal ca1-3': '1.3', 'Hippocampal ca4': '0.3', 'Hippocampal dentate gyrus': '0.3', 'Lamp5-lhx6 and chandelier': '1.2', 'Lower rhombic lip': '2.9', 'Mammillary body': '2.6', 'Medium spiny neuron': '0.2', 'Mge interneuron': '1.8', 'Midbrain-derived inhibitory': '1.8', 'Miscellaneous': '1.1', 'Splatter': '2.1', 'Thalamic excitatory': '2.0', 'Upper rhombic lip': '0.4', 'Upper-layer intratelencephalic': '1.1', 'Astrocyte': '0.7', 'Bergmann glia': '1.4', 'Central nervous system macrophage': '1.5', 'Choroid plexus epithelial cell': '6.8', 'Committed oligodendrocyte precursor': '0.7', 'Ependymal cell': '0.5', 'Oligodendrocyte': '1.8', 'Oligodendrocyte precursor cell': '0.4', 'Endothelial cell': '6.8', 'Pericyte': '0.3', 'Vascular associated smooth muscle cell': '2.1', 'Fibroblast': '1.5', 'Leukocyte': '2.0', 'Basophil': '0.3', 'Eosinophil': '0.0', 'Neutrophil': '0.0', 'Classical monocyte': '0.0', 'Non-classical monocyte': '0.1', 'Intermediate monocyte': '0.0', 'T-reg': '0.1', 'GdT-cell': '0.0', 'MAIT T-cell': '0.3', 'Memory CD4 T-cell': '0.0', 'Naive CD4 T-cell': '0.4', 'Memory CD8 T-cell': '0.1', 'Naive CD8 T-cell': '0.3', 'Memory B-cell': '0.0', 'Naive B-cell': '0.4', 'Plasmacytoid DC': '0.0', 'Myeloid DC': '0.0', 'NK-cell': '2.3', 'Total PBMC': '0.1', 'Vd2 gdTCR': '0.0', 'Memory CD4 T-cell Th1\\/Th17': '0.8', 'Memory CD4 T-cell Th17': '0.4', 'Memory CD4 T-cell Th2': '0.4', 'Non-Vd2 gdTCR': '0.0', 'Memory CD4 T-cell Th1': '0.6', 'Memory CD4 T-cell TFH': '0.3', 'Terminal effector memory CD4 T-cell': '0.3', 'Central memory CD8 T-cell': '0.3', 'Effector memory CD8 T-cell': '0.2', 'Terminal effector memory CD8 T-cell': '0.1', 'Non-switched memory B-cell': '0.1', 'Plasmablast': '0.0', 'Switched memory B-cell': '0.0', 'Exhausted memory B-cell': '0.6', 'Progenitor cell': '0.5', 'Memory T-reg': '0.1', 'Naive CD4 T-cell activated': '0.1', 'Naive CD8 T-cell activated': '0.1', 'Naive T-reg': '0.6'} | null | {'Adipose Tissue': 0.4057857641196013, 'Adrenal Gland': 0.8675186046511627, 'Bladder': 0.3579738095238095, 'Blood': 0.2379831011840688, 'Blood Vessel': 0.2933549932584269, 'Brain': 0.1101639227857683, 'Breast': 0.4449297167755991, 'Cervix Uteri': 0.3465005263157895, 'Colon': 0.3597065468549422, 'Esophagus': 0.2373859999999999, 'Fallopian Tube': 0.4340344444444444, 'Heart': 0.1957524343786295, 'Kidney': 0.6407348314606741, 'Liver': 0.2803746017699115, 'Lung': 0.4784568079584775, 'Muscle': 0.0852849676214196, 'Nerve': 0.2672600161550889, 'Ovary': 0.3940442222222222, 'Pancreas': 0.2423982621951219, 'Pituitary': 0.2461227561837455, 'Prostate': 0.3530606122448979, 'Salivary Gland': 0.6816697530864197, 'Skin': 0.2567115765616362, 'Small Intestine': 0.5665286096256684, 'Spleen': 2.1116, 'Stomach': 0.3458365459610028, 'Testis': 0.8320800554016621, 'Thyroid': 1.571570045941807, 'Uterus': 0.4048269718309859, 'Vagina': 0.316294358974359} | H3-4 | MARTKQTARKSTGGKAPRKQLATKVARKSAPATGGVKKPHRYRPGTVALREIRRYQKSTELLIRKLPFQRLMREIAQDFKTDLRFQSSAVMALQEACESYLVGLFEDTNLCVIHAKRVTIMPKDIQLARRIRGERA | Homo sapiens | Nucleus, Chromosome | Tissue enriched (testis) | {'Ciliated cells': '0.0', 'Basal respiratory cells': '0.0', 'Club cells': '0.0', 'Ionocytes': '0.0', 'Mucus glandular cells': '0.0', 'Serous glandular cells': '0.0', 'Gastric mucus-secreting cells': '0.0', 'Proximal enterocytes': '0.0', 'Paneth cells': '0.0', 'Distal enterocytes': '0.0', 'Intestinal goblet cells': '0.0', 'Exocrine glandular cells': '0.001', 'Basal prostatic cells': '0.0', 'Prostatic glandular cells': '0.0', 'Breast glandular cells': '0.203', 'Breast myoepithelial cells': '0.182', 'Glandular and luminal cells': '0.0', 'Secretory cells': '0.0', 'Basal keratinocytes': '0.0', 'Suprabasal keratinocytes': '0.0', 'Basal squamous epithelial cells': '0.0', 'Squamous epithelial cells': '0.0', 'Alveolar cells type 1': '0.086', 'Alveolar cells type 2': '0.103', 'Salivary duct cells': '0.0', 'Ductal cells': '0.088', 'Hepatocytes': '0.060', 'Cholangiocytes': '0.0', 'Proximal tubular cells': '-0.053', 'Distal tubular cells': '0.0', 'Collecting duct cells': '0.0', 'Mesothelial cells': '0.105', 'Sertoli cells': '-0.024', 'Granulosa cells': '0.0', 'Enteroendocrine cells': '0.0', 'Pancreatic endocrine cells': '0.0', 'Leydig cells': '-0.101', 'Excitatory neurons': '0.0', 'Inhibitory neurons': '0.0', 'Cone photoreceptor cells': '0.0', 'Rod photoreceptor cells': '0.0', 'Bipolar cells': '0.0', 'Horizontal cells': '0.0', 'Astrocytes': '0.0', 'Oligodendrocyte precursor cells': '0.0', 'Oligodendrocytes': '0.0', 'Microglial cells': '0.0', 'Muller glia cells': '0.0', 'Schwann cells': '0.119', 'Spermatogonia': '-0.086', 'Spermatocytes': '0.045', 'Early spermatids': '-0.038', 'Late spermatids': '0.096', 'Oocytes': '0.0', 'Cytotrophoblasts': '0.0', 'Syncytiotrophoblasts': '0.0', 'Extravillous trophoblasts': '0.0', 'Endothelial cells': '0.0', 'Lymphatic endothelial cells': '0.0', 'Cardiomyocytes': '0.119', 'Skeletal myocytes': '0.048', 'Smooth muscle cells': '0.0', 'Adipocytes': '0.0', 'Melanocytes': '0.057', 'Fibroblasts': '0.0', 'Peritubular cells': '-0.103', 'Endometrial stromal cells': '0.0', 'Ovarian stromal cells': '0.0', 'Undifferentiated cells': '0.0', 'T-cells': '0.0', 'B-cells': '0.0', 'Plasma cells': '0.0', 'Nk-cells': '0.0', 'Granulocytes': '0.0', 'Monocytes': '0.0', 'Macrophages': '0.0', 'Hofbauer cells': '0.0', 'Kupffer cells': '0.0', 'Dendritic cells': '0.0', 'Langerhans cells': '0.039', 'Erythroid cells': '-0.040', 'Adipocytes (Subcutaneous)': '-0.123', 'Adipocytes (Visceral)': '-0.056', 'Breast glandular cells (progenitors)': '0.205', 'Adipocytes (Breast)': '-0.083', 'Colon enterocytes': '0.051', 'Colon enteroendocrine cells': '-0.014', 'Enteric glia cells': '-0.001', 'Mitotic cells (Colon)': '0.031', 'Mitotic cells (Heart)': '0.103', 'Podocytes': '-0.034', 'Ascending Loop of Henle cells': '0.113', 'Intercalated cells': '-0.042', 'Cholangiocyte': '0.055', 'NK-cells (Liver)': '0.027', 'Respiratory ciliated cells': '0.037', 'Mitotic cells (Lung)': '0.039', 'NK-cells (Lung)': '-0.050', 'B-cells (Lung)': '-0.024', 'Alpha cells': '0.037', 'Beta cells': '0.034', 'Prostate glandular cells': '-0.062', 'Prostate basal glandular cells': '0.147', 'Urothelial cells': '0.162', 'Keratinocyte (other)': '0.009', 'Keratinocyte (granular)': 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72.25, 79.41, 84.92, 88.28, 91.72, 93.76, 95.26, 96.33, 96.0, 97.51, 97.34, 97.21, 97.64, 97.93, 97.72, 97.61, 97.82, 98.07, 97.69, 97.2, 97.91, 96.56, 96.41, 96.11, 96.64, 97.31, 97.27, 97.73, 95.35, 96.6, 97.88, 97.93, 96.55, 97.17, 97.52, 95.93, 95.96, 96.25, 96.67, 96.36, 95.75, 96.49, 95.85, 95.44, 94.05, 92.48, 94.36, 95.26, 95.45, 97.0, 95.01, 97.09, 96.75, 95.96, 96.32, 97.56, 97.47, 97.69, 97.65, 97.85, 97.75, 97.93, 97.32, 97.13, 97.34, 97.44, 96.69, 97.08, 97.83, 97.26, 97.31, 97.94, 97.54, 97.47, 97.16, 97.69, 97.65, 97.12, 97.35, 97.75, 97.67, 96.26, 97.73, 97.26, 97.84, 97.3, 96.22, 97.27, 96.37, 95.82, 95.62, 95.8, 95.96, 95.31, 94.33, 94.17, 93.29, 86.23, 67.22, 48.99] | [0.99, 0.91, 0.97, 0.87, 0.91, 0.93, 0.87, 0.9, 0.96, 0.89, 0.95, 0.85, 0.9, 0.84, 0.96, 0.92, 0.95, 0.96, 0.99, 0.97, 1.0, 0.88, 1.0, 0.87, 0.86, 0.81, 0.82, 0.98, 0.88, 0.73, 0.65, 0.96, 0.91, 0.66, 0.9, 0.73, 0.93, 0.94, 0.83, 0.78, 0.94, 0.55, 0.85, 0.96, 0.44, 0.4, 0.34, 0.45, 0.53, 0.47, 0.47, 0.5, 0.65, 0.69, 0.47, 0.74, 0.86, 0.38, 0.95, 0.57, 0.3, 0.56, 0.38, 0.8, 0.52, 0.57, 0.54, 0.12, 0.36, 0.66, 0.5, 0.11, 0.38, 0.63, 0.49, 0.13, 0.52, 0.84, 0.83, 0.67, 0.73, 0.89, 0.4, 0.96, 0.32, 0.71, 0.72, 0.59, 0.33, 0.12, 0.33, 0.52, 0.43, 0.01, 0.55, 0.56, 0.39, 0.11, 0.62, 0.46, 0.43, 0.52, 0.2, 0.1, 0.47, 0.6, 0.31, 0.0, 0.42, 0.62, 0.14, 0.0, 0.59, 0.81, 0.48, 0.9, 0.23, 0.89, 0.67, 0.51, 0.39, 0.66, 0.62, 0.04, 0.31, 0.44, 0.43, 0.04, 0.32, 0.75, 0.71, 0.37, 0.66, 0.34, 0.49, 0.98] | RING finger | Component of the RAG complex composed of core components RAG1 and RAG2, and associated component HMGB1 or HMGB2. | RAG | null | DCAF1,RAG1 , RAG2, HMGB1 or HMGB2, | H3 | mono | null | null | Homodimer | null | 81.264161 | 0.423183 | 85.880074 | 0.617059 | 2,630 |
P15919 | P15919 | 22199232 | UbiNet, UbiBrowser | Rag1 | MAASLPSTLSFSSAPDEIQHPQIKFSEWKFKLFRVRSFEKAPEEAQKEKDSSEGKPYLEQSPVVPEKPGGQNSILTQRALKLHPKFSKKFHADGKSSDKAVHQARLRHFCRICGNRFKSDGHSRRYPVHGPVDAKTQSLFRKKEKRVTSWPDLIARIFRIDVKADVDSIHPTEFCHDCWSIMHRKFSSSHSQVYFPRKVTVEWHPHTPSCDICFTAHRGLKRKRHQPNVQLSKKLKTVLNHARRDRRKRTQARVSSKEVLKKISNCSKIHLSTKLLAVDFPAHFVKSISCQICEHILADPVETSCKHLFCRICILRCLKVMGSYCPSCRYPCFPTDLESPVKSFLNILNSLMVKCPAQDCNEEVSLEKYNHHVSSHKESKETLVHINKGGRPRQHLLSLTRRAQKHRLRELKIQVKEFADKEEGGDVKAVCLTLFLLALRARNEHRQADELEAIMQGRGSGLQPAVCLAIRVNTFLSCSQYHKMYRTVKAITGRQIFQPLHALRNAEKVLLPGYHPFEWQPPLKNVSSRTDVGIIDGLSGLASSVDEYPVDTIAKRFRYDSALVSALMDMEEDILEGMRSQDLDDYLNGPFTVVVKESCDGMGDVSEKHGSGPAVPEKAVRFSFTVMRITIEHGSQNVKVFEEPKPNSELCCKPLCLMLADESDHETLTAILSPLIAEREAMKSSELTLEMGGIPRTFKFIFRGTGYDEKLVREVEGLEASGSVYICTLCDTTRLEASQNLVFHSITRSHAENLQRYEVWRSNPYHESVEELRDRVKGVSAKPFIETVPSIDALHCDIGNAAEFYKIFQLEIGEVYKHPNASKEERKRWQATLDKHLRKRMNLKPIMRMNGNFARKLMTQETVDAVCELIPSEERHEALRELMDLYLKMKPVWRSSCPAKECPESLCQYSFNSQRFAELLSTKFKYRYEGKITNYFHKTLAHVPEIIERDGSIGAWASEGNESGNKLFRRFRKMNARQSKCYEMEDVLKHHWLYTSKYLQKFMNAHNALKSSGFTMNSKETLGDPLGIEDSLESQDSMEF | Mus musculus | Nucleus | Not found | {} | 1RMD, 3GNA, 3GNB, 4WWX, 5ZDZ, 5ZE0, 5ZE1, 5ZE2, 6CG0, 6CIJ, 6CIK, 6CIL, 6CIM, 6OEM, 6OEN, 6OEO, 6OEP, 6OEQ, 6OER, 6OES, 6OET, 6V0V, 6XNX, 6XNY, 6XNZ | {} | Rag1 | MAASLPSTLSFSSAPDEIQHPQIKFSEWKFKLFRVRSFEKAPEEAQKEKDSSEGKPYLEQSPVVPEKPGGQNSILTQRALKLHPKFSKKFHADGKSSDKAVHQARLRHFCRICGNRFKSDGHSRRYPVHGPVDAKTQSLFRKKEKRVTSWPDLIARIFRIDVKADVDSIHPTEFCHDCWSIMHRKFSSSHSQVYFPRKVTVEWHPHTPSCDICFTAHRGLKRKRHQPNVQLSKKLKTVLNHARRDRRKRTQARVSSKEVLKKISNCSKIHLSTKLLAVDFPAHFVKSISCQICEHILADPVETSCKHLFCRICILRCLKVMGSYCPSCRYPCFPTDLESPVKSFLNILNSLMVKCPAQDCNEEVSLEKYNHHVSSHKESKETLVHINKGGRPRQHLLSLTRRAQKHRLRELKIQVKEFADKEEGGDVKAVCLTLFLLALRARNEHRQADELEAIMQGRGSGLQPAVCLAIRVNTFLSCSQYHKMYRTVKAITGRQIFQPLHALRNAEKVLLPGYHPFEWQPPLKNVSSRTDVGIIDGLSGLASSVDEYPVDTIAKRFRYDSALVSALMDMEEDILEGMRSQDLDDYLNGPFTVVVKESCDGMGDVSEKHGSGPAVPEKAVRFSFTVMRITIEHGSQNVKVFEEPKPNSELCCKPLCLMLADESDHETLTAILSPLIAEREAMKSSELTLEMGGIPRTFKFIFRGTGYDEKLVREVEGLEASGSVYICTLCDTTRLEASQNLVFHSITRSHAENLQRYEVWRSNPYHESVEELRDRVKGVSAKPFIETVPSIDALHCDIGNAAEFYKIFQLEIGEVYKHPNASKEERKRWQATLDKHLRKRMNLKPIMRMNGNFARKLMTQETVDAVCELIPSEERHEALRELMDLYLKMKPVWRSSCPAKECPESLCQYSFNSQRFAELLSTKFKYRYEGKITNYFHKTLAHVPEIIERDGSIGAWASEGNESGNKLFRRFRKMNARQSKCYEMEDVLKHHWLYTSKYLQKFMNAHNALKSSGFTMNSKETLGDPLGIEDSLESQDSMEF | Mus musculus | Nucleus | Not found | {} | 1RMD, 3GNA, 3GNB, 4WWX, 5ZDZ, 5ZE0, 5ZE1, 5ZE2, 6CG0, 6CIJ, 6CIK, 6CIL, 6CIM, 6OEM, 6OEN, 6OEO, 6OEP, 6OEQ, 6OER, 6OES, 6OET, 6V0V, 6XNX, 6XNY, 6XNZ | {} | [36.5, 27.04, 37.18, 30.53, 35.79, 34.36, 33.33, 34.84, 34.23, 27.69, 31.8, 31.99, 29.35, 32.42, 35.03, 29.59, 33.98, 36.75, 30.96, 39.96, 36.49, 42.36, 38.53, 39.82, 40.59, 36.99, 37.26, 34.02, 36.8, 34.76, 37.83, 37.17, 35.35, 29.75, 29.03, 27.77, 27.57, 27.35, 28.84, 28.63, 26.71, 31.27, 29.72, 29.82, 29.8, 31.82, 30.8, 28.4, 30.59, 29.36, 31.38, 35.52, 32.75, 29.61, 32.79, 33.08, 31.85, 30.93, 36.78, 35.01, 27.36, 37.3, 30.74, 37.56, 36.62, 29.53, 30.13, 37.65, 29.09, 30.15, 30.76, 27.85, 26.74, 30.47, 26.14, 28.61, 26.56, 27.86, 26.3, 30.1, 26.06, 28.34, 27.62, 33.19, 31.29, 32.28, 28.95, 30.12, 27.68, 29.35, 31.09, 28.28, 32.67, 39.61, 45.29, 51.24, 62.31, 70.32, 76.66, 81.08, 83.05, 86.69, 85.93, 85.43, 85.54, 87.56, 84.86, 86.83, 89.01, 90.25, 89.83, 87.5, 86.73, 86.08, 85.77, 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P15919 | Q60960 | 22199232 | UbiNet, UbiBrowser | Rag1 | 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1,451 |
P17221 | P34708 | 22199232 | UbiNet, UbiBrowser | fem-1 | MTPNGHHFRTVIYNAAAVGNLQRIKVFTINSRNDRQWIIDCFNSDQDGRYPLVIAARNGHANVVEYLLEIGADPSVRGVVEFDNENIQGTPPLWAASAAGHIEIVKLLIEKANADVNQATNTRSTPLRGACYDGHLDIVKYLLEKGADPHIPNRHGHTCLMIASYRNKVGIVEELLKTGIDVNKKTERGNTALHDAAESGNVEVVKILLKHGSVLMKDIQGVDPLMGAALSGFLDVLNVLADQMPSGIHKRDALKLLGSTLLDKKMDAMSAMNCWKQSMEVPLHADDLRLVREMETFFEPQEVYEYQREAQNIAQVELLDGNIEAQRMQALVIRERILGGAHTDVHYYLRFRGAVYCDMGQMNRCYDLWKHALELQQKHFAPLYYGTITTLQSFHETFSMSLNDFVNNHHANRNLRVRSSWVKYVFNGVCLELERAAAWTGAPLLEDTECCGKERCQHATEESEYKKLVYVAVHLVNVLERLSLPSAHIDDSDEEKEPKADVRRLMIVCHELHIPLLHHTLEERIPDSNSAELGLPKAAVLEQLLELDLDVNATDKNNDTPMHILLRAREFRKSLVRALLVRGTWLFARNRHGDVVLNVMKRMKALNHANFDDLPLGRHITLAGLVANAMRVKYPKKFVGVEEQMPLELRRFYLAH | Caenorhabditis elegans | Cytoplasm | Not found | {} | null | {} | tra-1 | MMAPSTEDPDTVVEAQRRGSFSKKKNANGWNKVELVDQCAKQMGSEDKQPGGGDVKTENDPSKNGLGSATSNFIQSSVPPSHQTLSNPLQLSPPAEASVAQQSGASQVFPTFQAALGASSDELLQPNATSSSTSSSASTSSIVPVVKFTNQTAPNGSTVATSVGQNVRLTINGKRVGRPPGTFKRPQNNAANSSNSGNDSDMMGDHDLTCRWKSCNSSFQTLKALVDHVQESHVQSTEQEHHAWRCEWEGCDRNETFKALYMLIVHVRRHTGEKPNKCEYPGCGKEYSRLENLKTHRRTHTGEKPYKCEFADCEKAFSNASDRAKHQNRTHSNLKPYSCQIPQCTKSYTDPSSLRKHIKAVHGDDEYEKAKKSRPANYSNRRRPDHRLAPPTGAMSHPYLATPNSGASVVAHSSVHQQNFINMALAQHHHNAQRAQQLMAATGNVMPMMDPASAAAAAQAQAHHQAQAQMLQTHMMQQAQIQAAAQMQAQVQHQAAMQAHAMQQAQMVLQNNLLGAQSLLSPFSPLLPPSRAPNVMAMLQTPPTPTSVAPMFDIMTSRAPMAPVVSAPTAPAPLVPAPVPASPVFDELREQMREVEPLQQQQQQEPMDQDLQDIRVDGDSDDEDEEEPRTPSGALLLPRGGNNGDGGFGGSGSSRASSGSGTMELSAAPISQNGSRASGSGERGMRSFLIADILQLAADFQNERLLSDVLDLAIFDTRDVRSLHNIYQVYIRAHKAIPITRRPLDWNETHQLHNLYHDPRFNRAEHQDSPAIRDRDTRFWRTIAEANTMRQRQIEPVPLDDDDEGYFDEMVHRVQNGRLNEQFMEGFESDDDDGFEDEDDVPGLGIAVYRGRRRVRREALKQANLDIQEAETAGRNVGGFGDEEDRNNRGHDQDRSFLDHYYPPMVVVVETESPQIVRDQEMMRQFEEAKKNVETDEIKKRAEAMQFGTSSSHHHTKTLLIQRALFDKTSSVRRSLLQFITISVDQEELRQSCHATSAPQGAHVVHNVVDEFDSIMRAQEDSNNRILLSLDIPAPSAVTGVSGSITHADNSALQLQQEQPTSSFSSWFPEDDPIYALPPPPPPPAPPRRRRSADNKDDSENIPKKPRHQF 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P19474 | O14920 | 19675099, BioGrid E3Net | UbiNet, UbiBrowser, 31181401 | TRIM21 | MASAARLTMMWEEVTCPICLDPFVEPVSIECGHSFCQECISQVGKGGGSVCPVCRQRFLLKNLRPNRQLANMVNNLKEISQEAREGTQGERCAVHGERLHLFCEKDGKALCWVCAQSRKHRDHAMVPLEEAAQEYQEKLQVALGELRRKQELAEKLEVEIAIKRADWKKTVETQKSRIHAEFVQQKNFLVEEEQRQLQELEKDEREQLRILGEKEAKLAQQSQALQELISELDRRCHSSALELLQEVIIVLERSESWNLKDLDITSPELRSVCHVPGLKKMLRTCAVHITLDPDTANPWLILSEDRRQVRLGDTQQSIPGNEERFDSYPMVLGAQHFHSGKHYWEVDVTGKEAWDLGVCRDSVRRKGHFLLSSKSGFWTIWLWNKQKYEAGTYPQTPLHLQVPPCQVGIFLDYEAGMVSFYNITDHGSLIYSFSECAFTGPLRPFFSPGFNDGGKNTAPLTLCPLNIGSQGSTDY | Homo sapiens | Cytoplasm, Cytoplasmic vesicle, autophagosome, Nucleus, Cytoplasm, P-body, Cytoplasm, Stress granule | Low tissue specificity | {'Ciliated cells': '3.8', 'Basal respiratory cells': '6.8', 'Club cells': '5.8', 'Ionocytes': '3.7', 'Mucus glandular cells': '4.8', 'Serous glandular cells': '2.3', 'Gastric mucus-secreting cells': '8.8', 'Proximal enterocytes': '8.9', 'Paneth cells': '3.9', 'Distal enterocytes': '8.5', 'Intestinal goblet cells': '8.4', 'Exocrine glandular cells': '-0.716', 'Basal prostatic cells': '5.4', 'Prostatic glandular cells': '5.0', 'Breast glandular cells': '0.298', 'Breast myoepithelial cells': '0.351', 'Glandular and luminal cells': '5.9', 'Secretory cells': '8.4', 'Basal keratinocytes': '3.2', 'Suprabasal keratinocytes': '2.7', 'Basal squamous epithelial cells': '6.4', 'Squamous epithelial cells': '4.3', 'Alveolar cells type 1': '0.116', 'Alveolar cells type 2': '0.115', 'Salivary duct cells': '3.0', 'Ductal cells': '0.700', 'Hepatocytes': '0.503', 'Cholangiocytes': '11.4', 'Proximal tubular cells': '0.175', 'Distal tubular cells': '0.0', 'Collecting duct cells': '5.8', 'Mesothelial cells': '0.451', 'Sertoli cells': '0.479', 'Granulosa cells': '4.8', 'Enteroendocrine cells': '3.7', 'Pancreatic endocrine cells': '3.4', 'Leydig cells': '0.632', 'Excitatory neurons': '0.2', 'Inhibitory neurons': '0.1', 'Cone photoreceptor cells': '0.0', 'Rod photoreceptor cells': '0.0', 'Bipolar cells': '0.7', 'Horizontal cells': '0.6', 'Astrocytes': '0.0', 'Oligodendrocyte precursor cells': '0.9', 'Oligodendrocytes': '0.1', 'Microglial cells': '1.8', 'Muller glia cells': '2.4', 'Schwann cells': '0.099', 'Spermatogonia': '0.401', 'Spermatocytes': '-0.062', 'Early spermatids': '-0.578', 'Late spermatids': '-0.618', 'Oocytes': '1.5', 'Cytotrophoblasts': '6.6', 'Syncytiotrophoblasts': '9.8', 'Extravillous trophoblasts': '10.0', 'Endothelial cells': '7.8', 'Lymphatic endothelial cells': '6.9', 'Cardiomyocytes': '0.335', 'Skeletal myocytes': '-0.080', 'Smooth muscle cells': '6.3', 'Adipocytes': '8.3', 'Melanocytes': '0.101', 'Fibroblasts': '6.5', 'Peritubular cells': '0.579', 'Endometrial stromal cells': '4.5', 'Ovarian stromal cells': '6.7', 'Undifferentiated cells': '5.9', 'T-cells': '9.9', 'B-cells': '8.8', 'Plasma cells': '5.0', 'Nk-cells': '15.1', 'Granulocytes': '6.2', 'Monocytes': '7.8', 'Macrophages': '8.5', 'Hofbauer cells': '9.9', 'Kupffer cells': '10.3', 'Dendritic cells': '8.0', 'Langerhans cells': '0.466', 'Erythroid cells': '-0.084', 'Adipocytes (Subcutaneous)': '-0.368', 'Adipocytes (Visceral)': '-0.167', 'Breast glandular cells (progenitors)': '0.190', 'Adipocytes (Breast)': '-0.382', 'Colon enterocytes': '0.004', 'Colon enteroendocrine cells': '0.196', 'Enteric glia cells': '-0.129', 'Mitotic cells (Colon)': '0.005', 'Mitotic cells (Heart)': '0.486', 'Podocytes': '-0.114', 'Ascending Loop of Henle cells': '0.371', 'Intercalated cells': '-0.097', 'Cholangiocyte': '0.375', 'NK-cells (Liver)': '-0.278', 'Respiratory ciliated cells': '-0.022', 'Mitotic cells (Lung)': '0.157', 'NK-cells (Lung)': '0.110', 'B-cells (Lung)': '-0.155', 'Alpha cells': '0.333', 'Beta cells': '0.161', 'Prostate glandular cells': '-0.162', 'Prostate basal glandular cells': '0.286', 'Urothelial cells': '0.283', 'Keratinocyte (other)': '0.121', 'Keratinocyte (granular)': '-0.008', 'Hair cortex cells': '-0.113', 'Inner root sheath cells': '-0.069', 'Outer root sheath cells': '0.125', 'Sebaceous gland cells': '0.110', 'Eccrine sweat gland cells': '0.070', 'Adipocytes (Skin)': '0.019', 'Mitotic cells (Skin)': '0.236', 'Parietal cells': '-0.609', 'Chief cells': '-0.599', 'Gastric mucous cells': '-0.193', 'Gastric enteroendocrine cells': '-0.441', 'Mitotic cells (Stomach)': '0.261', 'Parafollicular cells': '-0.028', 'Thyroid glandular cells': '0.094', 'Mitotic cells (Thyroid)': '0.242', 'Adrenal cortex cells': '0.619', 'Adrenal medulla cells': '0.063', 'Mitotic cells (Adrenal gland)': '0.483', 'Minor salivary glandular cells': '0.582', 'Minor salivary gland ductal cells': '0.072', 'Minor salivary gland basal cells': '0.229', 'Mitotic cells (Minor salivary gland)': '0.376', 'Adipocytes (Minor salivary gland)': '0.211', 'Somatotropes': '-0.121', 'Lactotropes': '-0.287', 'Gonadotropes': '0.004', 'Corticotropes': '-0.352', 'Thyrotropes': '-0.054', 'Undifferentiated cells (Pituitary gland)': '0.486', 'Mitotic cells (Spleen)': '-0.016', 'Platelets': '0.115', 'Erythrocytes': '0.098', 'Hematopoietic stem cells': '0.042', 'B-cells (Spleen)': '0.028', 'NK-cells (Spleen)': '0.157', 'Amygdala excitatory': '0.1', 'Cerebellar inhibitory': '0.2', 'Cge interneuron': '0.3', 'Deep-layer corticothalamic and 6b': '0.3', 'Deep-layer intratelencephalic': '0.1', 'Deep-layer near-projecting': '0.1', 'Eccentric medium spiny neuron': '0.4', 'Hippocampal ca1-3': '0.5', 'Hippocampal ca4': '0.1', 'Hippocampal dentate gyrus': '0.3', 'Lamp5-lhx6 and chandelier': '0.3', 'Lower rhombic lip': '0.2', 'Mammillary body': '0.4', 'Medium spiny neuron': '0.6', 'Mge interneuron': '0.1', 'Midbrain-derived inhibitory': '0.6', 'Miscellaneous': '0.6', 'Splatter': '0.5', 'Thalamic excitatory': '1.3', 'Upper rhombic lip': '0.1', 'Upper-layer intratelencephalic': '0.1', 'Astrocyte': '1.5', 'Bergmann glia': '1.5', 'Central nervous system macrophage': '6.0', 'Choroid plexus epithelial cell': '2.9', 'Committed oligodendrocyte precursor': '1.0', 'Ependymal cell': '1.3', 'Oligodendrocyte': '0.1', 'Oligodendrocyte precursor cell': '2.3', 'Endothelial cell': '6.4', 'Pericyte': '5.3', 'Vascular associated smooth muscle cell': '3.1', 'Fibroblast': '5.3', 'Leukocyte': '7.4', 'Basophil': '107.0', 'Eosinophil': '312.5', 'Neutrophil': '496.9', 'Classical monocyte': '25.8', 'Non-classical monocyte': '66.1', 'Intermediate monocyte': '117.0', 'T-reg': '72.1', 'GdT-cell': '89.5', 'MAIT T-cell': '61.2', 'Memory CD4 T-cell': '76.8', 'Naive CD4 T-cell': '47.0', 'Memory CD8 T-cell': '81.1', 'Naive CD8 T-cell': '43.5', 'Memory B-cell': '50.4', 'Naive B-cell': '38.5', 'Plasmacytoid DC': '47.5', 'Myeloid DC': '92.2', 'NK-cell': '88.9', 'Total PBMC': '83.8', 'Vd2 gdTCR': '67.8', 'Memory CD4 T-cell Th1\\/Th17': '48.0', 'Memory CD4 T-cell Th17': '54.6', 'Memory CD4 T-cell Th2': '54.8', 'Non-Vd2 gdTCR': '73.7', 'Memory CD4 T-cell Th1': '58.8', 'Memory CD4 T-cell TFH': '61.9', 'Terminal effector memory CD4 T-cell': '72.8', 'Central memory CD8 T-cell': '59.9', 'Effector memory CD8 T-cell': '90.7', 'Terminal effector memory CD8 T-cell': '75.8', 'Non-switched memory B-cell': '52.6', 'Plasmablast': '62.3', 'Switched memory B-cell': '55.8', 'Exhausted memory B-cell': '52.1', 'Progenitor cell': '44.7', 'Memory T-reg': '82.4', 'Naive CD4 T-cell activated': '133.9', 'Naive CD8 T-cell activated': '163.4', 'Naive T-reg': '54.7'} | 2IWG, 5JPX, 5OLM, 6FGA, 6S53, 7BBD, 8A58 | {'Adipose Tissue': 21.42795099667774, 'Adrenal Gland': 16.707763565891472, 'Bladder': 21.861904761904764, 'Blood': 61.11958557588805, 'Blood Vessel': 22.62928389513109, 'Brain': 4.305000416351249, 'Breast': 20.001740740740743, 'Cervix Uteri': 26.420526315789473, 'Colon': 23.40817458279846, 'Esophagus': 21.74157577854671, 'Fallopian Tube': 25.39, 'Heart': 6.66628106852497, 'Kidney': 13.61479775280899, 'Liver': 10.388, 'Lung': 32.00464878892734, 'Muscle': 3.944284806973848, 'Nerve': 25.39305008077545, 'Ovary': 30.51811111111111, 'Pancreas': 6.808080182926829, 'Pituitary': 12.995699646643107, 'Prostate': 21.00597551020408, 'Salivary Gland': 16.434148148148147, 'Skin': 17.851811498065228, 'Small Intestine': 28.907085561497325, 'Spleen': 50.16024896265561, 'Stomach': 19.072721448467966, 'Testis': 6.377013850415512, 'Thyroid': 21.553307810107196, 'Uterus': 29.83549295774648, 'Vagina': 21.551141025641027} | IKBKB | MSWSPSLTTQTCGAWEMKERLGTGGFGNVIRWHNQETGEQIAIKQCRQELSPRNRERWCLEIQIMRRLTHPNVVAARDVPEGMQNLAPNDLPLLAMEYCQGGDLRKYLNQFENCCGLREGAILTLLSDIASALRYLHENRIIHRDLKPENIVLQQGEQRLIHKIIDLGYAKELDQGSLCTSFVGTLQYLAPELLEQQKYTVTVDYWSFGTLAFECITGFRPFLPNWQPVQWHSKVRQKSEVDIVVSEDLNGTVKFSSSLPYPNNLNSVLAERLEKWLQLMLMWHPRQRGTDPTYGPNGCFKALDDILNLKLVHILNMVTGTIHTYPVTEDESLQSLKARIQQDTGIPEEDQELLQEAGLALIPDKPATQCISDGKLNEGHTLDMDLVFLFDNSKITYETQISPRPQPESVSCILQEPKRNLAFFQLRKVWGQVWHSIQTLKEDCNRLQQGQRAAMMNLLRNNSCLSKMKNSMASMSQQLKAKLDFFKTSIQIDLEKYSEQTEFGITSDKLLLAWREMEQAVELCGRENEVKLLVERMMALQTDIVDLQRSPMGRKQGGTLDDLEEQARELYRRLREKPRDQRTEGDSQEMVRLLLQAIQSFEKKVRVIYTQLSKTVVCKQKALELLPKVEEVVSLMNEDEKTVVRLQEKRQKELWNLLKIACSKVRGPVSGSPDSMNASRLSQPGQLMSQPSTASNSLPEPAKKSEELVAEAHNLCTLLENAIQDTVREQDQSFTALDWSWLQTEEEEHSCLEQAS | Homo sapiens | Cytoplasm, Nucleus, Membrane raft | Low tissue specificity | {'Ciliated cells': '19.2', 'Basal respiratory cells': '13.3', 'Club cells': '23.6', 'Ionocytes': '15.5', 'Mucus glandular cells': '27.4', 'Serous glandular cells': '20.9', 'Gastric mucus-secreting cells': '21.2', 'Proximal enterocytes': '10.9', 'Paneth cells': '9.1', 'Distal enterocytes': '13.1', 'Intestinal goblet cells': '18.9', 'Exocrine glandular cells': '-0.695', 'Basal prostatic cells': '20.7', 'Prostatic glandular cells': '20.1', 'Breast glandular cells': '0.701', 'Breast myoepithelial cells': '0.591', 'Glandular and luminal cells': '12.6', 'Secretory cells': '13.1', 'Basal keratinocytes': '23.4', 'Suprabasal keratinocytes': '22.9', 'Basal squamous epithelial cells': '23.9', 'Squamous epithelial cells': '16.1', 'Alveolar cells type 1': '0.076', 'Alveolar cells type 2': '-0.303', 'Salivary duct cells': '22.7', 'Ductal cells': '0.635', 'Hepatocytes': '0.287', 'Cholangiocytes': '13.4', 'Proximal tubular cells': '0.116', 'Distal tubular cells': '6.1', 'Collecting duct cells': '5.8', 'Mesothelial cells': '0.421', 'Sertoli cells': '0.595', 'Granulosa cells': '7.2', 'Enteroendocrine cells': '6.8', 'Pancreatic endocrine cells': '6.8', 'Leydig cells': '0.547', 'Excitatory neurons': '19.1', 'Inhibitory neurons': '19.7', 'Cone photoreceptor cells': '49.3', 'Rod photoreceptor cells': '53.7', 'Bipolar cells': '10.2', 'Horizontal cells': '12.6', 'Astrocytes': '18.3', 'Oligodendrocyte precursor cells': '16.0', 'Oligodendrocytes': '28.1', 'Microglial cells': '55.5', 'Muller glia cells': '9.7', 'Schwann cells': '0.159', 'Spermatogonia': '0.337', 'Spermatocytes': '0.000', 'Early spermatids': '-0.596', 'Late spermatids': '-0.680', 'Oocytes': '2.2', 'Cytotrophoblasts': '10.0', 'Syncytiotrophoblasts': '13.4', 'Extravillous trophoblasts': '4.7', 'Endothelial cells': '30.9', 'Lymphatic endothelial cells': '13.9', 'Cardiomyocytes': '0.362', 'Skeletal myocytes': '0.148', 'Smooth muscle cells': '11.7', 'Adipocytes': '29.6', 'Melanocytes': '-0.059', 'Fibroblasts': '11.6', 'Peritubular cells': '0.519', 'Endometrial stromal cells': '14.0', 'Ovarian stromal cells': '10.7', 'Undifferentiated cells': '11.6', 'T-cells': '24.5', 'B-cells': '26.2', 'Plasma cells': '9.7', 'Nk-cells': '40.4', 'Granulocytes': '25.0', 'Monocytes': '20.2', 'Macrophages': '26.6', 'Hofbauer cells': '19.0', 'Kupffer cells': '25.4', 'Dendritic cells': '41.3', 'Langerhans cells': '0.234', 'Erythroid cells': '0.046', 'Adipocytes (Subcutaneous)': '-0.322', 'Adipocytes (Visceral)': '-0.456', 'Breast glandular cells (progenitors)': '0.413', 'Adipocytes (Breast)': '-0.613', 'Colon enterocytes': '-0.097', 'Colon enteroendocrine cells': '0.158', 'Enteric glia cells': '0.210', 'Mitotic cells (Colon)': '0.091', 'Mitotic cells (Heart)': '0.512', 'Podocytes': '-0.140', 'Ascending Loop of Henle cells': '0.443', 'Intercalated cells': '-0.102', 'Cholangiocyte': '0.369', 'NK-cells (Liver)': '-0.220', 'Respiratory ciliated cells': '0.059', 'Mitotic cells (Lung)': '-0.040', 'NK-cells (Lung)': '0.350', 'B-cells (Lung)': '0.163', 'Alpha cells': '0.425', 'Beta cells': '0.318', 'Prostate glandular cells': '-0.015', 'Prostate basal glandular cells': '0.529', 'Urothelial cells': '0.571', 'Keratinocyte (other)': '0.208', 'Keratinocyte (granular)': '-0.132', 'Hair cortex cells': '-0.182', 'Inner root sheath cells': '-0.170', 'Outer root sheath cells': '0.089', 'Sebaceous gland cells': '-0.039', 'Eccrine sweat gland cells': '-0.149', 'Adipocytes (Skin)': '-0.209', 'Mitotic cells (Skin)': '0.172', 'Parietal cells': '-0.629', 'Chief cells': '-0.633', 'Gastric mucous cells': '-0.249', 'Gastric enteroendocrine cells': '-0.377', 'Mitotic cells (Stomach)': '0.133', 'Parafollicular cells': '-0.021', 'Thyroid glandular cells': '-0.035', 'Mitotic cells (Thyroid)': '0.098', 'Adrenal cortex cells': '0.378', 'Adrenal medulla cells': '-0.061', 'Mitotic cells (Adrenal gland)': '0.212', 'Minor salivary glandular cells': '0.604', 'Minor salivary gland ductal cells': '0.092', 'Minor salivary gland basal cells': '0.308', 'Mitotic cells (Minor salivary gland)': '0.409', 'Adipocytes (Minor salivary gland)': '0.204', 'Somatotropes': '0.018', 'Lactotropes': '-0.068', 'Gonadotropes': '0.050', 'Corticotropes': '-0.175', 'Thyrotropes': '0.012', 'Undifferentiated cells (Pituitary gland)': '0.283', 'Mitotic cells (Spleen)': '-0.331', 'Platelets': '-0.093', 'Erythrocytes': '-0.139', 'Hematopoietic stem cells': '-0.325', 'B-cells (Spleen)': '0.457', 'NK-cells (Spleen)': '0.454', 'Amygdala excitatory': '26.8', 'Cerebellar inhibitory': '34.9', 'Cge interneuron': '34.2', 'Deep-layer corticothalamic and 6b': '25.4', 'Deep-layer intratelencephalic': '26.0', 'Deep-layer near-projecting': '22.7', 'Eccentric medium spiny neuron': '26.2', 'Hippocampal ca1-3': '32.1', 'Hippocampal ca4': '39.4', 'Hippocampal dentate gyrus': '35.2', 'Lamp5-lhx6 and chandelier': '28.8', 'Lower rhombic lip': '29.7', 'Mammillary body': '29.3', 'Medium spiny neuron': '30.2', 'Mge interneuron': '27.3', 'Midbrain-derived inhibitory': '22.0', 'Miscellaneous': '25.7', 'Splatter': '24.5', 'Thalamic excitatory': '28.9', 'Upper rhombic lip': '41.6', 'Upper-layer intratelencephalic': '24.4', 'Astrocyte': '44.3', 'Bergmann glia': '31.4', 'Central nervous system macrophage': '177.2', 'Choroid plexus epithelial cell': '51.2', 'Committed oligodendrocyte precursor': '45.9', 'Ependymal cell': '87.0', 'Oligodendrocyte': '55.9', 'Oligodendrocyte precursor cell': '32.1', 'Endothelial cell': '229.2', 'Pericyte': '29.7', 'Vascular associated smooth muscle cell': '57.0', 'Fibroblast': '43.7', 'Leukocyte': '100.4', 'Basophil': '37.7', 'Eosinophil': '5.7', 'Neutrophil': '39.8', 'Classical monocyte': '41.2', 'Non-classical monocyte': '44.0', 'Intermediate monocyte': '33.2', 'T-reg': '36.3', 'GdT-cell': '4.6', 'MAIT T-cell': '26.1', 'Memory CD4 T-cell': '5.1', 'Naive CD4 T-cell': '68.9', 'Memory CD8 T-cell': '5.5', 'Naive CD8 T-cell': '67.5', 'Memory B-cell': '4.5', 'Naive B-cell': '79.2', 'Plasmacytoid DC': '53.7', 'Myeloid DC': '46.5', 'NK-cell': '79.9', 'Total PBMC': '26.5', 'Vd2 gdTCR': '32.3', 'Memory CD4 T-cell TFH': '83.9', 'Memory CD4 T-cell Th2': '94.2', 'Memory CD4 T-cell Th17': '79.6', 'Memory CD4 T-cell Th1\\/Th17': '64.9', 'Non-Vd2 gdTCR': '27.6', 'Memory CD4 T-cell Th1': '77.4', 'Terminal effector memory CD4 T-cell': '28.7', 'Central memory CD8 T-cell': '22.0', 'Effector memory CD8 T-cell': '30.9', 'Terminal effector memory CD8 T-cell': '26.4', 'Switched memory B-cell': '25.7', 'Plasmablast': '9.7', 'Non-switched memory B-cell': '33.0', 'Exhausted memory B-cell': '26.0', 'Progenitor cell': '32.5', 'Naive CD4 T-cell activated': '63.9', 'Naive CD8 T-cell activated': '59.8', 'Memory T-reg': '94.4', 'Naive T-reg': '75.9'} | 3BRT, 3BRV, 4E3C, 4KIK, 8OMV | {'Adipose Tissue': 34.76504983388705, 'Adrenal Gland': 28.13613953488372, 'Bladder': 41.54142857142857, 'Blood': 23.982386437029064, 'Blood Vessel': 30.419380524344568, 'Brain': 13.10757721423164, 'Breast': 44.40143790849673, 'Cervix Uteri': 45.844210526315784, 'Colon': 29.14707317073171, 'Esophagus': 33.743130795847755, 'Fallopian Tube': 48.4388888888889, 'Heart': 8.868621370499419, 'Kidney': 19.585955056179778, 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0.55, 0.5, 0.46, 0.51, 0.65, 0.74, 0.46, 0.59, 0.81, 0.56, 0.41, 0.78, 0.89, 0.59, 0.7, 0.37, 0.59, 0.73, 0.77, 0.78, 0.83, 0.96, 0.96, 0.75, 0.84, 0.94, 0.8, 0.84, 0.86, 0.95, 0.96, 0.95, 1.0] | RING finger | Component of a SCF(SKP2)-like complex containing CUL1, SKP1, TRIM21 and SKP2. | SCF | null | IRF8, CALR, CUL1, FBXW11, HSPA5, IKBKB, IRF3, SKP1 , VCP,SKP2, DCP2 ,ULK1, BECN1,GABARAP, GABARAPL1, GABARAPL2 , MAP1LC3C,SQSTM1,IRF3 , NMI, IFI35 , CUL1, TRIM21 | USP4, IKBKB, TRIM21, CDKN1B, IRF3, IRF8, MNI | mono, 63 | null | UBE2D2, UBE2D1, UBE2E1, UBE2E2 | Homotrimer | null | 90.718042 | 0.406716 | 85.899193 | 0.372328 | 888 |
P19474 | O95863 | 30502437 | UbiBrowser | TRIM21 | MASAARLTMMWEEVTCPICLDPFVEPVSIECGHSFCQECISQVGKGGGSVCPVCRQRFLLKNLRPNRQLANMVNNLKEISQEAREGTQGERCAVHGERLHLFCEKDGKALCWVCAQSRKHRDHAMVPLEEAAQEYQEKLQVALGELRRKQELAEKLEVEIAIKRADWKKTVETQKSRIHAEFVQQKNFLVEEEQRQLQELEKDEREQLRILGEKEAKLAQQSQALQELISELDRRCHSSALELLQEVIIVLERSESWNLKDLDITSPELRSVCHVPGLKKMLRTCAVHITLDPDTANPWLILSEDRRQVRLGDTQQSIPGNEERFDSYPMVLGAQHFHSGKHYWEVDVTGKEAWDLGVCRDSVRRKGHFLLSSKSGFWTIWLWNKQKYEAGTYPQTPLHLQVPPCQVGIFLDYEAGMVSFYNITDHGSLIYSFSECAFTGPLRPFFSPGFNDGGKNTAPLTLCPLNIGSQGSTDY | Homo sapiens | Cytoplasm, Cytoplasmic vesicle, autophagosome, Nucleus, Cytoplasm, P-body, Cytoplasm, Stress granule | Low tissue specificity | {'Ciliated cells': '3.8', 'Basal respiratory cells': '6.8', 'Club cells': '5.8', 'Ionocytes': '3.7', 'Mucus glandular cells': '4.8', 'Serous glandular cells': '2.3', 'Gastric mucus-secreting cells': '8.8', 'Proximal enterocytes': '8.9', 'Paneth cells': '3.9', 'Distal enterocytes': '8.5', 'Intestinal goblet cells': '8.4', 'Exocrine glandular cells': '-0.716', 'Basal prostatic cells': '5.4', 'Prostatic glandular cells': '5.0', 'Breast glandular cells': '0.298', 'Breast myoepithelial cells': '0.351', 'Glandular and luminal cells': '5.9', 'Secretory cells': '8.4', 'Basal keratinocytes': '3.2', 'Suprabasal keratinocytes': '2.7', 'Basal squamous epithelial cells': '6.4', 'Squamous epithelial cells': '4.3', 'Alveolar cells type 1': '0.116', 'Alveolar cells type 2': '0.115', 'Salivary duct cells': '3.0', 'Ductal cells': '0.700', 'Hepatocytes': '0.503', 'Cholangiocytes': '11.4', 'Proximal tubular cells': '0.175', 'Distal tubular cells': '0.0', 'Collecting duct cells': '5.8', 'Mesothelial cells': '0.451', 'Sertoli cells': '0.479', 'Granulosa cells': '4.8', 'Enteroendocrine cells': '3.7', 'Pancreatic endocrine cells': '3.4', 'Leydig cells': '0.632', 'Excitatory neurons': '0.2', 'Inhibitory neurons': '0.1', 'Cone photoreceptor cells': '0.0', 'Rod photoreceptor cells': '0.0', 'Bipolar cells': '0.7', 'Horizontal cells': '0.6', 'Astrocytes': '0.0', 'Oligodendrocyte precursor cells': '0.9', 'Oligodendrocytes': '0.1', 'Microglial cells': '1.8', 'Muller glia cells': '2.4', 'Schwann cells': '0.099', 'Spermatogonia': '0.401', 'Spermatocytes': '-0.062', 'Early spermatids': '-0.578', 'Late spermatids': '-0.618', 'Oocytes': '1.5', 'Cytotrophoblasts': '6.6', 'Syncytiotrophoblasts': '9.8', 'Extravillous trophoblasts': '10.0', 'Endothelial cells': '7.8', 'Lymphatic endothelial cells': '6.9', 'Cardiomyocytes': '0.335', 'Skeletal myocytes': '-0.080', 'Smooth muscle cells': '6.3', 'Adipocytes': '8.3', 'Melanocytes': '0.101', 'Fibroblasts': '6.5', 'Peritubular cells': '0.579', 'Endometrial stromal cells': '4.5', 'Ovarian stromal cells': '6.7', 'Undifferentiated cells': '5.9', 'T-cells': '9.9', 'B-cells': '8.8', 'Plasma cells': '5.0', 'Nk-cells': '15.1', 'Granulocytes': '6.2', 'Monocytes': '7.8', 'Macrophages': '8.5', 'Hofbauer cells': '9.9', 'Kupffer cells': '10.3', 'Dendritic cells': '8.0', 'Langerhans cells': '0.466', 'Erythroid cells': '-0.084', 'Adipocytes (Subcutaneous)': '-0.368', 'Adipocytes (Visceral)': '-0.167', 'Breast glandular cells (progenitors)': '0.190', 'Adipocytes (Breast)': '-0.382', 'Colon enterocytes': '0.004', 'Colon enteroendocrine cells': '0.196', 'Enteric glia cells': '-0.129', 'Mitotic cells (Colon)': '0.005', 'Mitotic cells (Heart)': '0.486', 'Podocytes': '-0.114', 'Ascending Loop of Henle cells': '0.371', 'Intercalated cells': '-0.097', 'Cholangiocyte': '0.375', 'NK-cells (Liver)': '-0.278', 'Respiratory ciliated cells': '-0.022', 'Mitotic cells (Lung)': '0.157', 'NK-cells (Lung)': '0.110', 'B-cells (Lung)': '-0.155', 'Alpha cells': '0.333', 'Beta cells': '0.161', 'Prostate glandular cells': '-0.162', 'Prostate basal glandular cells': '0.286', 'Urothelial cells': '0.283', 'Keratinocyte (other)': '0.121', 'Keratinocyte (granular)': '-0.008', 'Hair cortex cells': '-0.113', 'Inner root sheath cells': '-0.069', 'Outer root sheath cells': '0.125', 'Sebaceous gland cells': '0.110', 'Eccrine sweat gland cells': '0.070', 'Adipocytes (Skin)': '0.019', 'Mitotic cells (Skin)': '0.236', 'Parietal cells': '-0.609', 'Chief cells': '-0.599', 'Gastric mucous cells': '-0.193', 'Gastric enteroendocrine cells': '-0.441', 'Mitotic cells (Stomach)': '0.261', 'Parafollicular cells': '-0.028', 'Thyroid glandular cells': '0.094', 'Mitotic cells (Thyroid)': '0.242', 'Adrenal cortex cells': '0.619', 'Adrenal medulla cells': '0.063', 'Mitotic cells (Adrenal gland)': '0.483', 'Minor salivary glandular cells': '0.582', 'Minor salivary gland ductal cells': '0.072', 'Minor salivary gland basal cells': '0.229', 'Mitotic cells (Minor salivary gland)': '0.376', 'Adipocytes (Minor salivary gland)': '0.211', 'Somatotropes': '-0.121', 'Lactotropes': '-0.287', 'Gonadotropes': '0.004', 'Corticotropes': '-0.352', 'Thyrotropes': '-0.054', 'Undifferentiated cells (Pituitary gland)': '0.486', 'Mitotic cells (Spleen)': '-0.016', 'Platelets': '0.115', 'Erythrocytes': '0.098', 'Hematopoietic stem cells': '0.042', 'B-cells (Spleen)': '0.028', 'NK-cells (Spleen)': '0.157', 'Amygdala excitatory': '0.1', 'Cerebellar inhibitory': '0.2', 'Cge interneuron': '0.3', 'Deep-layer corticothalamic and 6b': '0.3', 'Deep-layer intratelencephalic': '0.1', 'Deep-layer near-projecting': '0.1', 'Eccentric medium spiny neuron': '0.4', 'Hippocampal ca1-3': '0.5', 'Hippocampal ca4': '0.1', 'Hippocampal dentate gyrus': '0.3', 'Lamp5-lhx6 and chandelier': '0.3', 'Lower rhombic lip': '0.2', 'Mammillary body': '0.4', 'Medium spiny neuron': '0.6', 'Mge interneuron': '0.1', 'Midbrain-derived inhibitory': '0.6', 'Miscellaneous': '0.6', 'Splatter': '0.5', 'Thalamic excitatory': '1.3', 'Upper rhombic lip': '0.1', 'Upper-layer intratelencephalic': '0.1', 'Astrocyte': '1.5', 'Bergmann glia': '1.5', 'Central nervous system macrophage': '6.0', 'Choroid plexus epithelial cell': '2.9', 'Committed oligodendrocyte precursor': '1.0', 'Ependymal cell': '1.3', 'Oligodendrocyte': '0.1', 'Oligodendrocyte precursor cell': '2.3', 'Endothelial cell': '6.4', 'Pericyte': '5.3', 'Vascular associated smooth muscle cell': '3.1', 'Fibroblast': '5.3', 'Leukocyte': '7.4', 'Basophil': '107.0', 'Eosinophil': '312.5', 'Neutrophil': '496.9', 'Classical monocyte': '25.8', 'Non-classical monocyte': '66.1', 'Intermediate monocyte': '117.0', 'T-reg': '72.1', 'GdT-cell': '89.5', 'MAIT T-cell': '61.2', 'Memory CD4 T-cell': '76.8', 'Naive CD4 T-cell': '47.0', 'Memory CD8 T-cell': '81.1', 'Naive CD8 T-cell': '43.5', 'Memory B-cell': '50.4', 'Naive B-cell': '38.5', 'Plasmacytoid DC': '47.5', 'Myeloid DC': '92.2', 'NK-cell': '88.9', 'Total PBMC': '83.8', 'Vd2 gdTCR': '67.8', 'Memory CD4 T-cell Th1\\/Th17': '48.0', 'Memory CD4 T-cell Th17': '54.6', 'Memory CD4 T-cell Th2': '54.8', 'Non-Vd2 gdTCR': '73.7', 'Memory CD4 T-cell Th1': '58.8', 'Memory CD4 T-cell TFH': '61.9', 'Terminal effector memory CD4 T-cell': '72.8', 'Central memory CD8 T-cell': '59.9', 'Effector memory CD8 T-cell': '90.7', 'Terminal effector memory CD8 T-cell': '75.8', 'Non-switched memory B-cell': '52.6', 'Plasmablast': '62.3', 'Switched memory B-cell': '55.8', 'Exhausted memory B-cell': '52.1', 'Progenitor cell': '44.7', 'Memory T-reg': '82.4', 'Naive CD4 T-cell activated': '133.9', 'Naive CD8 T-cell activated': '163.4', 'Naive T-reg': '54.7'} | 2IWG, 5JPX, 5OLM, 6FGA, 6S53, 7BBD, 8A58 | {'Adipose Tissue': 21.42795099667774, 'Adrenal Gland': 16.707763565891472, 'Bladder': 21.861904761904764, 'Blood': 61.11958557588805, 'Blood Vessel': 22.62928389513109, 'Brain': 4.305000416351249, 'Breast': 20.001740740740743, 'Cervix Uteri': 26.420526315789473, 'Colon': 23.40817458279846, 'Esophagus': 21.74157577854671, 'Fallopian Tube': 25.39, 'Heart': 6.66628106852497, 'Kidney': 13.61479775280899, 'Liver': 10.388, 'Lung': 32.00464878892734, 'Muscle': 3.944284806973848, 'Nerve': 25.39305008077545, 'Ovary': 30.51811111111111, 'Pancreas': 6.808080182926829, 'Pituitary': 12.995699646643107, 'Prostate': 21.00597551020408, 'Salivary Gland': 16.434148148148147, 'Skin': 17.851811498065228, 'Small Intestine': 28.907085561497325, 'Spleen': 50.16024896265561, 'Stomach': 19.072721448467966, 'Testis': 6.377013850415512, 'Thyroid': 21.553307810107196, 'Uterus': 29.83549295774648, 'Vagina': 21.551141025641027} | SNAI1 | MPRSFLVRKPSDPNRKPNYSELQDSNPEFTFQQPYDQAHLLAAIPPPEILNPTASLPMLIWDSVLAPQAQPIAWASLRLQESPRVAELTSLSDEDSGKGSQPPSPPSPAPSSFSSTSVSSLEAEAYAAFPGLGQVPKQLAQLSEAKDLQARKAFNCKYCNKEYLSLGALKMHIRSHTLPCVCGTCGKAFSRPWLLQGHVRTHTGEKPFSCPHCSRAFADRSNLRAHLQTHSDVKKYQCQACARTFSRMSLLHKHQESGCSGCPR | Homo sapiens | Nucleus, Cytoplasm | Tissue enhanced (adipose) | {'Ciliated cells': '3.0', 'Basal respiratory cells': '0.5', 'Club cells': '1.4', 'Ionocytes': '0.0', 'Mucus glandular cells': '3.4', 'Serous glandular cells': '1.3', 'Gastric mucus-secreting cells': '13.0', 'Proximal enterocytes': '1.8', 'Paneth cells': '1.7', 'Distal enterocytes': '3.0', 'Intestinal goblet cells': '4.6', 'Exocrine glandular cells': '-0.438', 'Basal prostatic cells': '0.8', 'Prostatic glandular cells': '0.5', 'Breast glandular cells': '-0.454', 'Breast myoepithelial cells': '-0.449', 'Glandular and luminal cells': '8.1', 'Secretory cells': '1.2', 'Basal keratinocytes': '1.4', 'Suprabasal keratinocytes': '1.3', 'Basal squamous epithelial cells': '2.4', 'Squamous epithelial cells': '7.0', 'Alveolar cells type 1': '0.107', 'Alveolar cells type 2': '-0.021', 'Salivary duct cells': '1.7', 'Ductal cells': '0.546', 'Hepatocytes': '0.050', 'Cholangiocytes': '3.8', 'Proximal tubular cells': '-0.020', 'Distal tubular cells': '0.0', 'Collecting duct cells': '0.0', 'Mesothelial cells': '-0.194', 'Sertoli cells': '0.277', 'Granulosa cells': '3.1', 'Enteroendocrine cells': '1.4', 'Pancreatic endocrine cells': '6.8', 'Leydig cells': '0.349', 'Excitatory neurons': '0.5', 'Inhibitory neurons': '0.4', 'Cone photoreceptor cells': '0.0', 'Rod photoreceptor cells': '0.4', 'Bipolar cells': '0.2', 'Horizontal cells': '1.3', 'Astrocytes': '0.3', 'Oligodendrocyte precursor cells': '0.0', 'Oligodendrocytes': '0.7', 'Microglial cells': '0.0', 'Muller glia cells': '1.5', 'Schwann cells': '0.083', 'Spermatogonia': '0.405', 'Spermatocytes': '0.168', 'Early spermatids': '-0.392', 'Late spermatids': '-0.387', 'Oocytes': '6.6', 'Cytotrophoblasts': '10.3', 'Syncytiotrophoblasts': '13.7', 'Extravillous trophoblasts': '91.2', 'Endothelial cells': '51.2', 'Lymphatic endothelial cells': '5.2', 'Cardiomyocytes': '-0.215', 'Skeletal myocytes': '-0.042', 'Smooth muscle cells': '13.9', 'Adipocytes': '160.3', 'Melanocytes': '-0.179', 'Fibroblasts': '24.6', 'Peritubular cells': '0.312', 'Endometrial stromal cells': '17.5', 'Ovarian stromal cells': '3.2', 'Undifferentiated cells': '4.8', 'T-cells': '9.3', 'B-cells': '7.6', 'Plasma cells': '2.4', 'Nk-cells': '2.8', 'Granulocytes': '0.4', 'Monocytes': '7.4', 'Macrophages': '28.7', 'Hofbauer cells': '15.4', 'Kupffer cells': '5.1', 'Dendritic cells': '5.3', 'Langerhans cells': '-0.145', 'Erythroid cells': '0.131', 'Adipocytes (Subcutaneous)': '0.058', 'Adipocytes (Visceral)': '0.161', 'Breast glandular cells (progenitors)': '-0.288', 'Adipocytes (Breast)': '0.628', 'Colon enterocytes': '-0.066', 'Colon enteroendocrine cells': '0.219', 'Enteric glia cells': '0.019', 'Mitotic cells (Colon)': '0.057', 'Mitotic cells (Heart)': '0.130', 'Podocytes': '0.135', 'Ascending Loop of Henle cells': '0.161', 'Intercalated cells': '0.039', 'Cholangiocyte': '0.486', 'NK-cells (Liver)': '-0.114', 'Respiratory ciliated cells': '-0.047', 'Mitotic cells (Lung)': '-0.124', 'NK-cells (Lung)': '0.163', 'B-cells (Lung)': '0.040', 'Alpha cells': '0.311', 'Beta cells': '0.197', 'Prostate glandular cells': '-0.199', 'Prostate basal glandular cells': '0.094', 'Urothelial cells': '0.216', 'Keratinocyte (other)': '-0.391', 'Keratinocyte (granular)': '-0.074', 'Hair cortex cells': '0.177', 'Inner root sheath cells': '0.166', 'Outer root sheath cells': '0.075', 'Sebaceous gland cells': '-0.016', 'Eccrine sweat gland cells': '0.300', 'Adipocytes (Skin)': '0.328', 'Mitotic cells (Skin)': '-0.180', 'Parietal cells': '-0.642', 'Chief cells': '-0.565', 'Gastric mucous cells': '-0.481', 'Gastric enteroendocrine cells': '-0.450', 'Mitotic cells (Stomach)': '-0.142', 'Parafollicular cells': '-0.012', 'Thyroid glandular cells': '0.192', 'Mitotic cells (Thyroid)': '-0.094', 'Adrenal cortex cells': '0.162', 'Adrenal medulla cells': '0.031', 'Mitotic cells (Adrenal gland)': '-0.001', 'Minor salivary glandular cells': '0.387', 'Minor salivary gland ductal cells': '0.039', 'Minor salivary gland basal cells': '0.081', 'Mitotic cells (Minor salivary gland)': '0.182', 'Adipocytes (Minor salivary gland)': '0.191', 'Somatotropes': '-0.152', 'Lactotropes': '-0.312', 'Gonadotropes': '-0.068', 'Corticotropes': '-0.105', 'Thyrotropes': '-0.112', 'Undifferentiated cells (Pituitary gland)': '0.126', 'Mitotic cells (Spleen)': '-0.360', 'Platelets': '-0.087', 'Erythrocytes': '-0.019', 'Hematopoietic stem cells': '-0.235', 'B-cells (Spleen)': '0.032', 'NK-cells (Spleen)': '0.100', 'Amygdala excitatory': '0.9', 'Cerebellar inhibitory': '1.0', 'Cge interneuron': '0.5', 'Deep-layer corticothalamic and 6b': '0.5', 'Deep-layer intratelencephalic': '0.6', 'Deep-layer near-projecting': '0.7', 'Eccentric medium spiny neuron': '0.8', 'Hippocampal ca1-3': '0.7', 'Hippocampal ca4': '0.2', 'Hippocampal dentate gyrus': '0.2', 'Lamp5-lhx6 and chandelier': '0.5', 'Lower rhombic lip': '0.5', 'Mammillary body': '0.6', 'Medium spiny neuron': '1.3', 'Mge interneuron': '0.5', 'Midbrain-derived inhibitory': '0.4', 'Miscellaneous': '0.8', 'Splatter': '0.7', 'Thalamic excitatory': '0.6', 'Upper rhombic lip': '0.9', 'Upper-layer intratelencephalic': '1.0', 'Astrocyte': '0.8', 'Bergmann glia': '0.1', 'Central nervous system macrophage': '0.2', 'Choroid plexus epithelial cell': '0.0', 'Committed oligodendrocyte precursor': '0.5', 'Ependymal cell': '0.1', 'Oligodendrocyte': '0.7', 'Oligodendrocyte precursor cell': '1.1', 'Endothelial cell': '1.4', 'Pericyte': '0.9', 'Vascular associated smooth muscle cell': '0.6', 'Fibroblast': '3.6', 'Leukocyte': '0.4', 'Basophil': '5.0', 'Eosinophil': '0.0', 'Neutrophil': '0.8', 'Classical monocyte': '85.9', 'Non-classical monocyte': '0.7', 'Intermediate monocyte': '2.3', 'T-reg': '0.8', 'GdT-cell': '0.0', 'MAIT T-cell': '0.9', 'Memory CD4 T-cell': '0.0', 'Naive CD4 T-cell': '12.8', 'Memory CD8 T-cell': '0.0', 'Naive CD8 T-cell': '21.0', 'Memory B-cell': '0.0', 'Naive B-cell': '3.4', 'Plasmacytoid DC': '7.4', 'Myeloid DC': '31.8', 'NK-cell': '4.1', 'Total PBMC': '10.9', 'Vd2 gdTCR': '2.5', 'Memory CD4 T-cell Th1\\/Th17': '7.5', 'Memory CD4 T-cell Th17': '8.6', 'Memory CD4 T-cell Th2': '12.3', 'Non-Vd2 gdTCR': '3.3', 'Memory CD4 T-cell Th1': '14.8', 'Memory CD4 T-cell TFH': '5.9', 'Terminal effector memory CD4 T-cell': '1.2', 'Central memory CD8 T-cell': '1.4', 'Effector memory CD8 T-cell': '1.3', 'Terminal effector memory CD8 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6.574512345679012, 'Skin': 9.561411221669433, 'Small Intestine': 5.927605347593582, 'Spleen': 17.578145228215767, 'Stomach': 9.012349860724234, 'Testis': 9.602681440443211, 'Thyroid': 34.892254211332315, 'Uterus': 12.107514084507043, 'Vagina': 9.61338782051282} | [37.42, 45.2, 56.71, 57.57, 65.92, 71.8, 70.72, 70.19, 75.03, 81.06, 81.95, 82.13, 85.0, 89.84, 89.65, 93.29, 90.82, 89.33, 90.46, 84.59, 85.8, 87.81, 91.19, 89.54, 92.34, 94.82, 95.66, 94.94, 93.26, 90.29, 93.55, 91.65, 95.23, 95.54, 95.57, 95.25, 94.22, 93.77, 94.59, 93.99, 92.38, 92.01, 90.02, 87.48, 84.99, 84.15, 85.0, 86.86, 92.88, 92.09, 93.98, 92.61, 92.26, 94.16, 91.11, 93.0, 91.84, 92.37, 91.85, 87.92, 88.9, 90.86, 91.4, 93.27, 94.09, 93.72, 91.24, 89.47, 90.87, 89.3, 89.1, 89.45, 87.1, 86.17, 84.68, 82.73, 79.4, 75.43, 73.11, 66.81, 58.79, 56.4, 57.14, 50.0, 41.66, 49.45, 46.98, 52.48, 63.42, 77.27, 83.26, 88.11, 83.9, 82.85, 82.24, 80.46, 83.44, 86.75, 90.36, 90.91, 92.35, 94.22, 93.97, 92.59, 91.88, 91.55, 92.54, 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0.69, 0.53, 0.79, 0.82, 0.63, 0.79, 0.69, 0.41, 0.25, 0.61, 0.0, 0.9, 0.67, 0.35, 0.73, 0.46, 0.77, 0.21, 0.79, 0.5, 0.45, 0.45, 0.38, 0.09, 0.6, 0.66, 0.11, 0.33, 0.62, 0.4, 0.39, 0.53, 0.27, 0.82, 0.1, 0.57, 0.03, 0.93, 0.72, 0.41, 0.6, 0.56, 0.75, 0.23, 0.54, 0.53, 0.57, 0.57, 0.45, 0.16, 0.58, 0.2, 0.13, 0.41, 0.3, 0.62, 0.44, 0.58, 0.4, 0.6, 0.59, 0.67, 0.27, 0.64, 0.17, 0.82, 0.75, 0.45, 0.96, 0.64, 0.29, 0.2, 0.18, 0.3, 0.67, 0.55, 0.52, 0.14, 0.67, 0.23, 0.07, 0.34, 0.44, 0.44, 0.38, 0.54, 0.69, 0.49, 0.51, 0.8, 0.38, 0.52, 0.02, 0.89, 0.46, 0.5, 0.53, 0.59, 0.45, 0.18, 0.21, 0.35, 0.64, 0.57, 0.45, 0.11, 0.58, 0.64, 0.12, 0.52, 0.73, 0.75, 0.65, 0.16, 0.98, 0.56, 0.41, 0.95, 0.99] | RING finger | Component of a SCF(SKP2)-like complex containing CUL1, SKP1, TRIM21 and SKP2. | SCF | null | IRF8, CALR, CUL1, FBXW11, HSPA5, IKBKB, IRF3, SKP1 , VCP,SKP2, DCP2 ,ULK1, BECN1,GABARAP, GABARAPL1, GABARAPL2 , MAP1LC3C,SQSTM1,IRF3 , NMI, IFI35 , CUL1, TRIM21 | USP4, IKBKB, TRIM21, CDKN1B, IRF3, IRF8, MNI | mono, 63 | null | UBE2D2, UBE2D1, UBE2E1, UBE2E2 | Homotrimer | null | 90.718042 | 0.406716 | 55.993182 | 0.692045 | 2,496 |
P19474 | P01857 | 18641315 | UbiBrowser | TRIM21 | MASAARLTMMWEEVTCPICLDPFVEPVSIECGHSFCQECISQVGKGGGSVCPVCRQRFLLKNLRPNRQLANMVNNLKEISQEAREGTQGERCAVHGERLHLFCEKDGKALCWVCAQSRKHRDHAMVPLEEAAQEYQEKLQVALGELRRKQELAEKLEVEIAIKRADWKKTVETQKSRIHAEFVQQKNFLVEEEQRQLQELEKDEREQLRILGEKEAKLAQQSQALQELISELDRRCHSSALELLQEVIIVLERSESWNLKDLDITSPELRSVCHVPGLKKMLRTCAVHITLDPDTANPWLILSEDRRQVRLGDTQQSIPGNEERFDSYPMVLGAQHFHSGKHYWEVDVTGKEAWDLGVCRDSVRRKGHFLLSSKSGFWTIWLWNKQKYEAGTYPQTPLHLQVPPCQVGIFLDYEAGMVSFYNITDHGSLIYSFSECAFTGPLRPFFSPGFNDGGKNTAPLTLCPLNIGSQGSTDY | Homo sapiens | Cytoplasm, Cytoplasmic vesicle, autophagosome, Nucleus, Cytoplasm, P-body, Cytoplasm, Stress granule | Low tissue specificity | {'Ciliated cells': '3.8', 'Basal respiratory cells': '6.8', 'Club cells': '5.8', 'Ionocytes': '3.7', 'Mucus glandular cells': '4.8', 'Serous glandular cells': '2.3', 'Gastric mucus-secreting cells': '8.8', 'Proximal enterocytes': '8.9', 'Paneth cells': '3.9', 'Distal enterocytes': '8.5', 'Intestinal goblet cells': '8.4', 'Exocrine glandular cells': '-0.716', 'Basal prostatic cells': '5.4', 'Prostatic glandular cells': '5.0', 'Breast glandular cells': '0.298', 'Breast myoepithelial cells': '0.351', 'Glandular and luminal cells': '5.9', 'Secretory cells': '8.4', 'Basal keratinocytes': '3.2', 'Suprabasal keratinocytes': '2.7', 'Basal squamous epithelial cells': '6.4', 'Squamous epithelial cells': '4.3', 'Alveolar cells type 1': '0.116', 'Alveolar cells type 2': '0.115', 'Salivary duct cells': '3.0', 'Ductal cells': '0.700', 'Hepatocytes': '0.503', 'Cholangiocytes': '11.4', 'Proximal tubular cells': '0.175', 'Distal tubular cells': '0.0', 'Collecting duct cells': '5.8', 'Mesothelial cells': '0.451', 'Sertoli cells': '0.479', 'Granulosa cells': '4.8', 'Enteroendocrine cells': '3.7', 'Pancreatic endocrine cells': '3.4', 'Leydig cells': '0.632', 'Excitatory neurons': '0.2', 'Inhibitory neurons': '0.1', 'Cone photoreceptor cells': '0.0', 'Rod photoreceptor cells': '0.0', 'Bipolar cells': '0.7', 'Horizontal cells': '0.6', 'Astrocytes': '0.0', 'Oligodendrocyte precursor cells': '0.9', 'Oligodendrocytes': '0.1', 'Microglial cells': '1.8', 'Muller glia cells': '2.4', 'Schwann cells': '0.099', 'Spermatogonia': '0.401', 'Spermatocytes': '-0.062', 'Early spermatids': '-0.578', 'Late spermatids': '-0.618', 'Oocytes': '1.5', 'Cytotrophoblasts': '6.6', 'Syncytiotrophoblasts': '9.8', 'Extravillous trophoblasts': '10.0', 'Endothelial cells': '7.8', 'Lymphatic endothelial cells': '6.9', 'Cardiomyocytes': '0.335', 'Skeletal myocytes': '-0.080', 'Smooth muscle cells': '6.3', 'Adipocytes': '8.3', 'Melanocytes': '0.101', 'Fibroblasts': '6.5', 'Peritubular cells': '0.579', 'Endometrial stromal cells': '4.5', 'Ovarian stromal cells': '6.7', 'Undifferentiated cells': '5.9', 'T-cells': '9.9', 'B-cells': '8.8', 'Plasma cells': '5.0', 'Nk-cells': '15.1', 'Granulocytes': '6.2', 'Monocytes': '7.8', 'Macrophages': '8.5', 'Hofbauer cells': '9.9', 'Kupffer cells': '10.3', 'Dendritic cells': '8.0', 'Langerhans cells': '0.466', 'Erythroid cells': '-0.084', 'Adipocytes (Subcutaneous)': '-0.368', 'Adipocytes (Visceral)': '-0.167', 'Breast glandular cells (progenitors)': '0.190', 'Adipocytes (Breast)': '-0.382', 'Colon enterocytes': '0.004', 'Colon enteroendocrine cells': '0.196', 'Enteric glia cells': '-0.129', 'Mitotic cells (Colon)': '0.005', 'Mitotic cells (Heart)': '0.486', 'Podocytes': '-0.114', 'Ascending Loop of Henle cells': '0.371', 'Intercalated cells': '-0.097', 'Cholangiocyte': '0.375', 'NK-cells (Liver)': '-0.278', 'Respiratory ciliated cells': '-0.022', 'Mitotic cells (Lung)': '0.157', 'NK-cells (Lung)': '0.110', 'B-cells (Lung)': '-0.155', 'Alpha cells': '0.333', 'Beta cells': '0.161', 'Prostate glandular cells': '-0.162', 'Prostate basal glandular cells': '0.286', 'Urothelial cells': '0.283', 'Keratinocyte (other)': '0.121', 'Keratinocyte (granular)': '-0.008', 'Hair cortex cells': '-0.113', 'Inner root sheath cells': '-0.069', 'Outer root sheath cells': '0.125', 'Sebaceous gland cells': '0.110', 'Eccrine sweat gland cells': '0.070', 'Adipocytes (Skin)': '0.019', 'Mitotic cells (Skin)': '0.236', 'Parietal cells': '-0.609', 'Chief cells': '-0.599', 'Gastric mucous cells': '-0.193', 'Gastric enteroendocrine cells': '-0.441', 'Mitotic cells (Stomach)': '0.261', 'Parafollicular cells': '-0.028', 'Thyroid glandular cells': '0.094', 'Mitotic cells (Thyroid)': '0.242', 'Adrenal cortex cells': '0.619', 'Adrenal medulla cells': '0.063', 'Mitotic cells (Adrenal gland)': '0.483', 'Minor salivary glandular cells': '0.582', 'Minor salivary gland ductal cells': '0.072', 'Minor salivary gland basal cells': '0.229', 'Mitotic cells (Minor salivary gland)': '0.376', 'Adipocytes (Minor salivary gland)': '0.211', 'Somatotropes': '-0.121', 'Lactotropes': '-0.287', 'Gonadotropes': '0.004', 'Corticotropes': '-0.352', 'Thyrotropes': '-0.054', 'Undifferentiated cells (Pituitary gland)': '0.486', 'Mitotic cells (Spleen)': '-0.016', 'Platelets': '0.115', 'Erythrocytes': '0.098', 'Hematopoietic stem cells': '0.042', 'B-cells (Spleen)': '0.028', 'NK-cells (Spleen)': '0.157', 'Amygdala excitatory': '0.1', 'Cerebellar inhibitory': '0.2', 'Cge interneuron': '0.3', 'Deep-layer corticothalamic and 6b': '0.3', 'Deep-layer intratelencephalic': '0.1', 'Deep-layer near-projecting': '0.1', 'Eccentric medium spiny neuron': '0.4', 'Hippocampal ca1-3': '0.5', 'Hippocampal ca4': '0.1', 'Hippocampal dentate gyrus': '0.3', 'Lamp5-lhx6 and chandelier': '0.3', 'Lower rhombic lip': '0.2', 'Mammillary body': '0.4', 'Medium spiny neuron': '0.6', 'Mge interneuron': '0.1', 'Midbrain-derived inhibitory': '0.6', 'Miscellaneous': '0.6', 'Splatter': '0.5', 'Thalamic excitatory': '1.3', 'Upper rhombic lip': '0.1', 'Upper-layer intratelencephalic': '0.1', 'Astrocyte': '1.5', 'Bergmann glia': '1.5', 'Central nervous system macrophage': '6.0', 'Choroid plexus epithelial cell': '2.9', 'Committed oligodendrocyte precursor': '1.0', 'Ependymal cell': '1.3', 'Oligodendrocyte': '0.1', 'Oligodendrocyte precursor cell': '2.3', 'Endothelial cell': '6.4', 'Pericyte': '5.3', 'Vascular associated smooth muscle cell': '3.1', 'Fibroblast': '5.3', 'Leukocyte': '7.4', 'Basophil': '107.0', 'Eosinophil': '312.5', 'Neutrophil': '496.9', 'Classical monocyte': '25.8', 'Non-classical monocyte': '66.1', 'Intermediate monocyte': '117.0', 'T-reg': '72.1', 'GdT-cell': '89.5', 'MAIT T-cell': '61.2', 'Memory CD4 T-cell': '76.8', 'Naive CD4 T-cell': '47.0', 'Memory CD8 T-cell': '81.1', 'Naive CD8 T-cell': '43.5', 'Memory B-cell': '50.4', 'Naive B-cell': '38.5', 'Plasmacytoid DC': '47.5', 'Myeloid DC': '92.2', 'NK-cell': '88.9', 'Total PBMC': '83.8', 'Vd2 gdTCR': '67.8', 'Memory CD4 T-cell Th1\\/Th17': '48.0', 'Memory CD4 T-cell Th17': '54.6', 'Memory CD4 T-cell Th2': '54.8', 'Non-Vd2 gdTCR': '73.7', 'Memory CD4 T-cell Th1': '58.8', 'Memory CD4 T-cell TFH': '61.9', 'Terminal effector memory CD4 T-cell': '72.8', 'Central memory CD8 T-cell': '59.9', 'Effector memory CD8 T-cell': '90.7', 'Terminal effector memory CD8 T-cell': '75.8', 'Non-switched memory B-cell': '52.6', 'Plasmablast': '62.3', 'Switched memory B-cell': '55.8', 'Exhausted memory B-cell': '52.1', 'Progenitor cell': '44.7', 'Memory T-reg': '82.4', 'Naive CD4 T-cell activated': '133.9', 'Naive CD8 T-cell activated': '163.4', 'Naive T-reg': '54.7'} | 2IWG, 5JPX, 5OLM, 6FGA, 6S53, 7BBD, 8A58 | {'Adipose Tissue': 21.42795099667774, 'Adrenal Gland': 16.707763565891472, 'Bladder': 21.861904761904764, 'Blood': 61.11958557588805, 'Blood Vessel': 22.62928389513109, 'Brain': 4.305000416351249, 'Breast': 20.001740740740743, 'Cervix Uteri': 26.420526315789473, 'Colon': 23.40817458279846, 'Esophagus': 21.74157577854671, 'Fallopian Tube': 25.39, 'Heart': 6.66628106852497, 'Kidney': 13.61479775280899, 'Liver': 10.388, 'Lung': 32.00464878892734, 'Muscle': 3.944284806973848, 'Nerve': 25.39305008077545, 'Ovary': 30.51811111111111, 'Pancreas': 6.808080182926829, 'Pituitary': 12.995699646643107, 'Prostate': 21.00597551020408, 'Salivary Gland': 16.434148148148147, 'Skin': 17.851811498065228, 'Small Intestine': 28.907085561497325, 'Spleen': 50.16024896265561, 'Stomach': 19.072721448467966, 'Testis': 6.377013850415512, 'Thyroid': 21.553307810107196, 'Uterus': 29.83549295774648, 'Vagina': 21.551141025641027} | IGHG1 | ASTKGPSVFPLAPSSKSTSGGTAALGCLVKDYFPEPVTVSWNSGALTSGVHTFPAVLQSSGLYSLSSVVTVPSSSLGTQTYICNVNHKPSNTKVDKKVEPKSCDKTHTCPPCPAPELLGGPSVFLFPPKPKDTLMISRTPEVTCVVVDVSHEDPEVKFNWYVDGVEVHNAKTKPREEQYNSTYRVVSVLTVLHQDWLNGKEYKCKVSNKALPAPIEKTISKAKGQPREPQVYTLPPSRDELTKNQVSLTCLVKGFYPSDIAVEWESNGQPENNYKTTPPVLDSDGSFFLYSKLTVDKSRWQQGNVFSCSVMHEALHNHYTQKSLSLSPELQLEESCAEAQDGELDGLWTTITIFITLFLLSVCYSATVTFFKVKWIFSSVVDLKQTIIPDYRNMIGQGA | Homo sapiens | Secreted, Cell membrane | Group enriched (lymphoid tissue, urinary bladder) | {'Ciliated cells': '1.3', 'Basal respiratory cells': '0.0', 'Club cells': '1.0', 'Ionocytes': '0.0', 'Mucus glandular cells': '41.2', 'Serous glandular cells': '17.9', 'Gastric mucus-secreting cells': '8.8', 'Proximal enterocytes': '0.0', 'Paneth cells': '1.9', 'Distal enterocytes': '1.1', 'Intestinal goblet cells': '1.2', 'Exocrine glandular cells': '-0.084', 'Basal prostatic cells': '31.9', 'Prostatic glandular cells': '0.1', 'Breast glandular cells': '0.309', 'Breast myoepithelial cells': '0.221', 'Glandular and luminal cells': '0.0', 'Secretory cells': '2.5', 'Basal keratinocytes': '138.7', 'Suprabasal keratinocytes': '1.3', 'Basal squamous epithelial cells': '0.0', 'Squamous epithelial cells': '0.0', 'Alveolar cells type 1': '-0.078', 'Alveolar cells type 2': '0.130', 'Salivary duct cells': '0.8', 'Ductal cells': '0.263', 'Hepatocytes': '0.360', 'Cholangiocytes': '5.7', 'Proximal tubular cells': '0.293', 'Distal tubular cells': '0.0', 'Collecting duct cells': '0.0', 'Mesothelial cells': '0.260', 'Sertoli cells': '0.026', 'Granulosa cells': '0.0', 'Enteroendocrine cells': '2.2', 'Pancreatic endocrine cells': '0.0', 'Leydig cells': '0.209', 'Excitatory neurons': '0.0', 'Inhibitory neurons': '0.0', 'Cone photoreceptor cells': '0.0', 'Rod photoreceptor cells': '0.0', 'Bipolar cells': '0.0', 'Horizontal cells': '0.0', 'Astrocytes': '0.0', 'Oligodendrocyte precursor cells': '0.0', 'Oligodendrocytes': '0.0', 'Microglial cells': '0.0', 'Muller glia cells': '0.2', 'Schwann cells': '0.087', 'Spermatogonia': '0.209', 'Spermatocytes': '0.019', 'Early spermatids': '-0.164', 'Late spermatids': '-0.143', 'Oocytes': '0.0', 'Cytotrophoblasts': '0.0', 'Syncytiotrophoblasts': '0.1', 'Extravillous trophoblasts': '0.0', 'Endothelial cells': '12.9', 'Lymphatic endothelial cells': '56.3', 'Cardiomyocytes': '0.451', 'Skeletal myocytes': '0.041', 'Smooth muscle cells': '7.5', 'Adipocytes': '2.2', 'Melanocytes': '-0.049', 'Fibroblasts': '18.4', 'Peritubular cells': '0.230', 'Endometrial stromal cells': '0.1', 'Ovarian stromal cells': '0.0', 'Undifferentiated cells': '0.8', 'T-cells': '51.3', 'B-cells': '2014.2', 'Plasma cells': '12047.8', 'Nk-cells': '0.4', 'Granulocytes': '7.1', 'Monocytes': '0.9', 'Macrophages': '27.3', 'Hofbauer cells': '0.0', 'Kupffer cells': '59.2', 'Dendritic cells': '0.4', 'Langerhans cells': '0.084', 'Erythroid cells': '0.056', 'Adipocytes (Subcutaneous)': '-0.054', 'Adipocytes (Visceral)': '-0.192', 'Breast glandular cells (progenitors)': '0.159', 'Adipocytes (Breast)': '-0.259', 'Colon enterocytes': '0.280', 'Colon enteroendocrine cells': '0.066', 'Enteric glia cells': '-0.249', 'Mitotic cells (Colon)': '0.291', 'Mitotic cells (Heart)': '0.328', 'Podocytes': '-0.019', 'Ascending Loop of Henle cells': '-0.003', 'Intercalated cells': '0.046', 'Cholangiocyte': '0.382', 'NK-cells (Liver)': '-0.094', 'Respiratory ciliated cells': '0.002', 'Mitotic cells (Lung)': '0.058', 'NK-cells (Lung)': '-0.030', 'B-cells (Lung)': '0.320', 'Alpha cells': '0.280', 'Beta cells': '0.067', 'Prostate glandular cells': '-0.123', 'Prostate basal glandular cells': '0.083', 'Urothelial cells': '0.219', 'Keratinocyte (other)': '-0.243', 'Keratinocyte (granular)': '-0.195', 'Hair cortex cells': '0.041', 'Inner root sheath cells': '0.120', 'Outer root sheath cells': '0.218', 'Sebaceous gland cells': '0.283', 'Eccrine sweat gland cells': '0.137', 'Adipocytes (Skin)': '0.262', 'Mitotic cells (Skin)': '0.008', 'Parietal cells': '0.515', 'Chief cells': '0.529', 'Gastric mucous cells': '0.593', 'Gastric enteroendocrine cells': '0.528', 'Mitotic cells (Stomach)': '0.294', 'Parafollicular cells': '-0.097', 'Thyroid glandular cells': '-0.141', 'Mitotic cells (Thyroid)': '0.257', 'Adrenal cortex cells': '0.318', 'Adrenal medulla cells': '0.222', 'Mitotic cells (Adrenal gland)': '0.302', 'Minor salivary glandular cells': '0.249', 'Minor salivary gland ductal cells': '0.252', 'Minor salivary gland basal cells': '-0.289', 'Mitotic cells (Minor salivary gland)': '-0.161', 'Adipocytes (Minor salivary gland)': '0.105', 'Somatotropes': '-0.020', 'Lactotropes': '-0.042', 'Gonadotropes': '-0.026', 'Corticotropes': '-0.183', 'Thyrotropes': '-0.140', 'Undifferentiated cells (Pituitary gland)': '0.180', 'Mitotic cells (Spleen)': '0.426', 'Platelets': '0.102', 'Erythrocytes': '0.118', 'Hematopoietic stem cells': '0.212', 'B-cells (Spleen)': '-0.344', 'NK-cells (Spleen)': '-0.317', 'Amygdala excitatory': '0.0', 'Cerebellar inhibitory': '0.3', 'Cge interneuron': '0.0', 'Deep-layer corticothalamic and 6b': '0.0', 'Deep-layer intratelencephalic': '0.0', 'Deep-layer near-projecting': '0.0', 'Eccentric medium spiny neuron': '0.0', 'Hippocampal ca1-3': '0.0', 'Hippocampal ca4': '0.0', 'Hippocampal dentate gyrus': '0.0', 'Lamp5-lhx6 and chandelier': '0.0', 'Lower rhombic lip': '0.0', 'Mammillary body': '0.0', 'Medium spiny neuron': '0.0', 'Mge interneuron': '0.1', 'Midbrain-derived inhibitory': '0.0', 'Miscellaneous': '0.0', 'Splatter': '0.0', 'Thalamic excitatory': '0.0', 'Upper rhombic lip': '0.0', 'Upper-layer intratelencephalic': '0.0', 'Astrocyte': '1.1', 'Bergmann glia': '0.0', 'Central nervous system macrophage': '0.0', 'Choroid plexus epithelial cell': '0.0', 'Committed oligodendrocyte precursor': '0.0', 'Ependymal cell': '0.0', 'Oligodendrocyte': '0.0', 'Oligodendrocyte precursor cell': '0.0', 'Endothelial cell': '0.1', 'Pericyte': '0.1', 'Vascular associated smooth muscle cell': '0.0', 'Fibroblast': '0.0', 'Leukocyte': '12.0', 'Basophil': '7.5', 'Eosinophil': '0.1', 'Neutrophil': '15.6', 'Classical monocyte': '0.1', 'Non-classical monocyte': '0.1', 'Intermediate monocyte': '1.4', 'T-reg': '6.1', 'GdT-cell': '0.3', 'MAIT T-cell': '2.4', 'Memory CD4 T-cell': '0.6', 'Naive CD4 T-cell': '0.6', 'Memory CD8 T-cell': '0.3', 'Naive CD8 T-cell': '0.6', 'Memory B-cell': '768.6', 'Naive B-cell': '4.8', 'Plasmacytoid DC': '5.1', 'Myeloid DC': '1.8', 'NK-cell': '0.2', 'Total PBMC': '550.1', 'Vd2 gdTCR': '0.5', 'Memory CD4 T-cell Th1\\/Th17': '0.0', 'Memory CD4 T-cell Th17': '0.0', 'Memory CD4 T-cell Th2': '0.0', 'Non-Vd2 gdTCR': '0.3', 'Memory CD4 T-cell Th1': '0.0', 'Memory CD4 T-cell TFH': '0.5', 'Terminal effector memory CD4 T-cell': '0.1', 'Central memory CD8 T-cell': '0.4', 'Effector memory CD8 T-cell': '0.9', 'Terminal effector memory CD8 T-cell': '1.1', 'Non-switched memory B-cell': '667.8', 'Plasmablast': '59770.2', 'Switched memory B-cell': '1700.1', 'Exhausted memory B-cell': '3133.6', 'Progenitor cell': '330.4', 'Memory T-reg': '0.7', 'Naive CD4 T-cell activated': '0.0', 'Naive CD8 T-cell activated': '0.1', 'Naive T-reg': '0.5'} | 1AJ7, 1AQK, 1AXS, 1BEY, 1D5B, 1D5I, 1D6V, 1DFB, 1DN2, 1E4K, 1FC1, 1FC2, 1FCC, 1GAF, 1H3T, 1H3U, 1H3V, 1H3W, 1H3X, 1H3Y, 1HKL, 1HZH, 1I7Z, 1L6X, 1N7M, 1OQO, 1OQX, 1PG7, 1T83, 1T89, 1VGE, 2DTS, 2GJ7, 2I5Y, 2IWG, 2J6E, 2JB5, 2JB6, 2O5X, 2O5Y, 2O5Z, 2OSL, 2QAD, 2QL1, 2QQK, 2QQL, 2QQN, 2QR0, 2R56, 2RCS, 2VXQ, 2WAH, 3AGV, 3AVE, 3AY4, 3B2U, 3B2V, 3BDY, 3BE1, 3BKY, 3BN9, 3BQU, 3C08, 3C09, 3C2S, 3CFJ, 3CFK, 3CSY, 3D0L, 3D0V, 3D6G, 3D85, 3DJ9, 3DNK, 3DO3, 3DRO, 3DRQ, 3DVG, 3DVN, 3EYF, 3EYO, 3EYQ, 3FJT, 3MCL, 3O11, 3RY6, 3S7G, 3SGJ, 3SGK, 3TV3, 3TWC, 3TYG, 3U0W, 3U7W, 3U7Y, 3V7M, 3V8C, 3V95, 3WJJ, 3WJL, 3WKN, 3WN5, 4ACP, 4B7I, 4BM7, 4BSV, 4BSW, 4BYH, 4CDH, 4D9Q, 4D9R, 4DAG, 4DZ8, 4EOW, 4HIX, 4J12, 4KU1, 4LLD, 4LLM, 4LLQ, 4N0U, 4NQS, 4NQT, 4NQU, 4NWT, 4NWU, 4O4Y, 4O51, 4Q6Y, 4Q74, 4Q7D, 4W4N, 4W4O, 4WI2, 4WI3, 4WI4, 4WI5, 4WI6, 4WI7, 4WI8, 4WI9, 4X4M, 4X98, 4X99, 4XMP, 4XNY, 4XNZ, 4XXD, 4ZNE, 5BW7, 5C7K, 5D4Q, 5D6D, 5DI8, 5DJ0, 5DJ2, 5DJ6, 5DJ8, 5DJA, 5DJC, 5DJD, 5DJX, 5DJY, 5DJZ, 5DK0, 5DK2, 5DVK, 5DVL, 5DVM, 5DVN, 5DVO, 5GSQ, 5HSF, 5HY9, 5HYE, 5HYF, 5HYI, 5IQ7, 5IQ9, 5IW3, 5IW6, 5JIH, 5JII, 5JIK, 5K33, 5K64, 5K65, 5K8D, 5KWG, 5M3V, 5TPS, 5U4Y, 5U52, 5U66, 5V43, 5V4E, 6DCV, 6DCW, 6DE7, 6F2Z, 6G1E, 6N35, 6YT7, 7KWO, 7LUR, 7Q15, 7Q3P, 7WSO, 8DIN, 8DIR, 8DJ7 | {'Adipose Tissue': 134.2874100830565, 'Adrenal Gland': 63.992507015503875, 'Bladder': 299.7919523809524, 'Blood': 400.4973345532831, 'Blood Vessel': 113.45827017228464, 'Brain': 1.983178770628312, 'Breast': 101.45040047930284, 'Cervix Uteri': 312.4572105263158, 'Colon': 84.98622890885751, 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0.74, 0.57, 0.62, 0.85, 0.57, 0.44, 0.7, 0.39, 0.98, 0.49, 0.33, 0.02, 0.16, 0.37, 0.07, 0.07, 0.01, 0.11, 0.02, 0.42, 0.07, 0.68, 0.22, 0.75, 0.2, 0.04, 0.23, 0.75, 0.37, 0.3, 0.47, 0.02, 0.29, 0.0, 0.24, 0.0, 0.3, 0.11, 0.75, 0.34, 0.12, 0.92, 0.67, 0.52, 0.25, 0.48, 0.42, 0.55, 0.17, 0.38, 0.13, 0.47, 0.8, 0.56, 0.84, 0.43, 0.4, 0.65, 0.07, 0.45, 0.1, 0.47, 0.23, 0.44, 0.66, 0.14, 0.54, 0.85, 0.73, 0.27, 0.36, 0.79, 0.66, 0.79, 0.49, 0.01, 0.18, 0.0, 0.23, 0.0, 0.17, 0.0, 0.35, 0.16, 0.0, 0.24, 0.02, 0.38, 0.29, 0.14, 0.12, 0.11, 0.35, 0.03, 0.32, 0.07, 0.75, 0.77, 0.69, 0.74, 0.13, 0.8, 0.51, 0.29, 0.79, 0.44, 0.51, 0.83, 0.37, 0.45, 0.66, 0.3, 0.99, 0.56, 0.38, 0.01, 0.19, 0.28, 0.02, 0.41, 0.0, 0.48, 0.0, 0.2, 0.02, 0.47, 0.2, 0.5, 0.26, 0.04, 0.6, 0.68, 0.45, 0.22, 0.44, 0.0, 0.07, 0.0, 0.04, 0.0, 0.05, 0.0, 0.19, 0.25, 0.08, 0.86, 0.91, 0.27, 0.45, 0.28, 0.42, 0.45, 0.55, 0.09, 0.49, 0.45, 0.88, 0.92, 0.9, 0.98] | RING finger | Component of a SCF(SKP2)-like complex containing CUL1, SKP1, TRIM21 and SKP2. | SCF | null | IRF8, CALR, CUL1, FBXW11, HSPA5, IKBKB, IRF3, SKP1 , VCP,SKP2, DCP2 ,ULK1, BECN1,GABARAP, GABARAPL1, GABARAPL2 , MAP1LC3C,SQSTM1,IRF3 , NMI, IFI35 , CUL1, TRIM21 | USP4, IKBKB, TRIM21, CDKN1B, IRF3, IRF8, MNI | mono, 63 | null | UBE2D2, UBE2D1, UBE2E1, UBE2E2 | Homotrimer | null | 90.718042 | 0.406716 | 91.473121 | 0.395909 | 1,984 |
P19474 | P19474 | 16472766, E3Net | UbiNet, UbiBrowser, 31181401 | TRIM21 | MASAARLTMMWEEVTCPICLDPFVEPVSIECGHSFCQECISQVGKGGGSVCPVCRQRFLLKNLRPNRQLANMVNNLKEISQEAREGTQGERCAVHGERLHLFCEKDGKALCWVCAQSRKHRDHAMVPLEEAAQEYQEKLQVALGELRRKQELAEKLEVEIAIKRADWKKTVETQKSRIHAEFVQQKNFLVEEEQRQLQELEKDEREQLRILGEKEAKLAQQSQALQELISELDRRCHSSALELLQEVIIVLERSESWNLKDLDITSPELRSVCHVPGLKKMLRTCAVHITLDPDTANPWLILSEDRRQVRLGDTQQSIPGNEERFDSYPMVLGAQHFHSGKHYWEVDVTGKEAWDLGVCRDSVRRKGHFLLSSKSGFWTIWLWNKQKYEAGTYPQTPLHLQVPPCQVGIFLDYEAGMVSFYNITDHGSLIYSFSECAFTGPLRPFFSPGFNDGGKNTAPLTLCPLNIGSQGSTDY | Homo sapiens | Cytoplasm, Cytoplasmic vesicle, autophagosome, Nucleus, Cytoplasm, P-body, Cytoplasm, Stress granule | Low tissue specificity | {'Ciliated cells': '3.8', 'Basal respiratory cells': '6.8', 'Club cells': '5.8', 'Ionocytes': '3.7', 'Mucus glandular cells': '4.8', 'Serous glandular cells': '2.3', 'Gastric mucus-secreting cells': '8.8', 'Proximal enterocytes': '8.9', 'Paneth cells': '3.9', 'Distal enterocytes': '8.5', 'Intestinal goblet cells': '8.4', 'Exocrine glandular cells': '-0.716', 'Basal prostatic cells': '5.4', 'Prostatic glandular cells': '5.0', 'Breast glandular cells': '0.298', 'Breast myoepithelial cells': '0.351', 'Glandular and luminal cells': '5.9', 'Secretory cells': '8.4', 'Basal keratinocytes': '3.2', 'Suprabasal keratinocytes': '2.7', 'Basal squamous epithelial cells': '6.4', 'Squamous epithelial cells': '4.3', 'Alveolar cells type 1': '0.116', 'Alveolar cells type 2': '0.115', 'Salivary duct cells': '3.0', 'Ductal cells': '0.700', 'Hepatocytes': '0.503', 'Cholangiocytes': '11.4', 'Proximal tubular cells': '0.175', 'Distal tubular cells': '0.0', 'Collecting duct cells': '5.8', 'Mesothelial cells': '0.451', 'Sertoli cells': '0.479', 'Granulosa cells': '4.8', 'Enteroendocrine cells': '3.7', 'Pancreatic endocrine cells': '3.4', 'Leydig cells': '0.632', 'Excitatory neurons': '0.2', 'Inhibitory neurons': '0.1', 'Cone photoreceptor cells': '0.0', 'Rod photoreceptor cells': '0.0', 'Bipolar cells': '0.7', 'Horizontal cells': '0.6', 'Astrocytes': '0.0', 'Oligodendrocyte precursor cells': '0.9', 'Oligodendrocytes': '0.1', 'Microglial cells': '1.8', 'Muller glia cells': '2.4', 'Schwann cells': '0.099', 'Spermatogonia': '0.401', 'Spermatocytes': '-0.062', 'Early spermatids': '-0.578', 'Late spermatids': '-0.618', 'Oocytes': '1.5', 'Cytotrophoblasts': '6.6', 'Syncytiotrophoblasts': '9.8', 'Extravillous trophoblasts': '10.0', 'Endothelial cells': '7.8', 'Lymphatic endothelial cells': '6.9', 'Cardiomyocytes': '0.335', 'Skeletal myocytes': '-0.080', 'Smooth muscle cells': '6.3', 'Adipocytes': '8.3', 'Melanocytes': '0.101', 'Fibroblasts': '6.5', 'Peritubular cells': '0.579', 'Endometrial stromal cells': '4.5', 'Ovarian stromal cells': '6.7', 'Undifferentiated cells': '5.9', 'T-cells': '9.9', 'B-cells': '8.8', 'Plasma cells': '5.0', 'Nk-cells': '15.1', 'Granulocytes': '6.2', 'Monocytes': '7.8', 'Macrophages': '8.5', 'Hofbauer cells': '9.9', 'Kupffer cells': '10.3', 'Dendritic cells': '8.0', 'Langerhans cells': '0.466', 'Erythroid cells': '-0.084', 'Adipocytes (Subcutaneous)': '-0.368', 'Adipocytes (Visceral)': '-0.167', 'Breast glandular cells (progenitors)': '0.190', 'Adipocytes (Breast)': '-0.382', 'Colon enterocytes': '0.004', 'Colon enteroendocrine cells': '0.196', 'Enteric glia cells': '-0.129', 'Mitotic cells (Colon)': '0.005', 'Mitotic cells (Heart)': '0.486', 'Podocytes': '-0.114', 'Ascending Loop of Henle cells': '0.371', 'Intercalated cells': '-0.097', 'Cholangiocyte': '0.375', 'NK-cells (Liver)': '-0.278', 'Respiratory ciliated cells': '-0.022', 'Mitotic cells (Lung)': '0.157', 'NK-cells (Lung)': '0.110', 'B-cells (Lung)': '-0.155', 'Alpha cells': '0.333', 'Beta cells': '0.161', 'Prostate glandular cells': '-0.162', 'Prostate basal glandular cells': '0.286', 'Urothelial cells': '0.283', 'Keratinocyte (other)': '0.121', 'Keratinocyte (granular)': '-0.008', 'Hair cortex cells': '-0.113', 'Inner root sheath cells': '-0.069', 'Outer root sheath cells': '0.125', 'Sebaceous gland cells': '0.110', 'Eccrine sweat gland cells': '0.070', 'Adipocytes (Skin)': '0.019', 'Mitotic cells (Skin)': '0.236', 'Parietal cells': '-0.609', 'Chief cells': '-0.599', 'Gastric mucous cells': '-0.193', 'Gastric enteroendocrine cells': '-0.441', 'Mitotic cells (Stomach)': '0.261', 'Parafollicular cells': '-0.028', 'Thyroid glandular cells': '0.094', 'Mitotic cells (Thyroid)': '0.242', 'Adrenal cortex cells': '0.619', 'Adrenal medulla cells': '0.063', 'Mitotic cells (Adrenal gland)': '0.483', 'Minor salivary glandular cells': '0.582', 'Minor salivary gland ductal cells': '0.072', 'Minor salivary gland basal cells': '0.229', 'Mitotic cells (Minor salivary gland)': '0.376', 'Adipocytes (Minor salivary gland)': '0.211', 'Somatotropes': '-0.121', 'Lactotropes': '-0.287', 'Gonadotropes': '0.004', 'Corticotropes': '-0.352', 'Thyrotropes': '-0.054', 'Undifferentiated cells (Pituitary gland)': '0.486', 'Mitotic cells (Spleen)': '-0.016', 'Platelets': '0.115', 'Erythrocytes': '0.098', 'Hematopoietic stem cells': '0.042', 'B-cells (Spleen)': '0.028', 'NK-cells (Spleen)': '0.157', 'Amygdala excitatory': '0.1', 'Cerebellar inhibitory': '0.2', 'Cge interneuron': '0.3', 'Deep-layer corticothalamic and 6b': '0.3', 'Deep-layer intratelencephalic': '0.1', 'Deep-layer near-projecting': '0.1', 'Eccentric medium spiny neuron': '0.4', 'Hippocampal ca1-3': '0.5', 'Hippocampal ca4': '0.1', 'Hippocampal dentate gyrus': '0.3', 'Lamp5-lhx6 and chandelier': '0.3', 'Lower rhombic lip': '0.2', 'Mammillary body': '0.4', 'Medium spiny neuron': '0.6', 'Mge interneuron': '0.1', 'Midbrain-derived inhibitory': '0.6', 'Miscellaneous': '0.6', 'Splatter': '0.5', 'Thalamic excitatory': '1.3', 'Upper rhombic lip': '0.1', 'Upper-layer intratelencephalic': '0.1', 'Astrocyte': '1.5', 'Bergmann glia': '1.5', 'Central nervous system macrophage': '6.0', 'Choroid plexus epithelial cell': '2.9', 'Committed oligodendrocyte precursor': '1.0', 'Ependymal cell': '1.3', 'Oligodendrocyte': '0.1', 'Oligodendrocyte precursor cell': '2.3', 'Endothelial cell': '6.4', 'Pericyte': '5.3', 'Vascular associated smooth muscle cell': '3.1', 'Fibroblast': '5.3', 'Leukocyte': '7.4', 'Basophil': '107.0', 'Eosinophil': '312.5', 'Neutrophil': '496.9', 'Classical monocyte': '25.8', 'Non-classical monocyte': '66.1', 'Intermediate monocyte': '117.0', 'T-reg': '72.1', 'GdT-cell': '89.5', 'MAIT T-cell': '61.2', 'Memory CD4 T-cell': '76.8', 'Naive CD4 T-cell': '47.0', 'Memory CD8 T-cell': '81.1', 'Naive CD8 T-cell': '43.5', 'Memory B-cell': '50.4', 'Naive B-cell': '38.5', 'Plasmacytoid DC': '47.5', 'Myeloid DC': '92.2', 'NK-cell': '88.9', 'Total PBMC': '83.8', 'Vd2 gdTCR': '67.8', 'Memory CD4 T-cell Th1\\/Th17': '48.0', 'Memory CD4 T-cell Th17': '54.6', 'Memory CD4 T-cell Th2': '54.8', 'Non-Vd2 gdTCR': '73.7', 'Memory CD4 T-cell Th1': '58.8', 'Memory CD4 T-cell TFH': '61.9', 'Terminal effector memory CD4 T-cell': '72.8', 'Central memory CD8 T-cell': '59.9', 'Effector memory CD8 T-cell': '90.7', 'Terminal effector memory CD8 T-cell': '75.8', 'Non-switched memory B-cell': '52.6', 'Plasmablast': '62.3', 'Switched memory B-cell': '55.8', 'Exhausted memory B-cell': '52.1', 'Progenitor cell': '44.7', 'Memory T-reg': '82.4', 'Naive CD4 T-cell activated': '133.9', 'Naive CD8 T-cell activated': '163.4', 'Naive T-reg': '54.7'} | 2IWG, 5JPX, 5OLM, 6FGA, 6S53, 7BBD, 8A58 | {'Adipose Tissue': 21.42795099667774, 'Adrenal Gland': 16.707763565891472, 'Bladder': 21.861904761904764, 'Blood': 61.11958557588805, 'Blood Vessel': 22.62928389513109, 'Brain': 4.305000416351249, 'Breast': 20.001740740740743, 'Cervix Uteri': 26.420526315789473, 'Colon': 23.40817458279846, 'Esophagus': 21.74157577854671, 'Fallopian Tube': 25.39, 'Heart': 6.66628106852497, 'Kidney': 13.61479775280899, 'Liver': 10.388, 'Lung': 32.00464878892734, 'Muscle': 3.944284806973848, 'Nerve': 25.39305008077545, 'Ovary': 30.51811111111111, 'Pancreas': 6.808080182926829, 'Pituitary': 12.995699646643107, 'Prostate': 21.00597551020408, 'Salivary Gland': 16.434148148148147, 'Skin': 17.851811498065228, 'Small Intestine': 28.907085561497325, 'Spleen': 50.16024896265561, 'Stomach': 19.072721448467966, 'Testis': 6.377013850415512, 'Thyroid': 21.553307810107196, 'Uterus': 29.83549295774648, 'Vagina': 21.551141025641027} | TRIM21 | MASAARLTMMWEEVTCPICLDPFVEPVSIECGHSFCQECISQVGKGGGSVCPVCRQRFLLKNLRPNRQLANMVNNLKEISQEAREGTQGERCAVHGERLHLFCEKDGKALCWVCAQSRKHRDHAMVPLEEAAQEYQEKLQVALGELRRKQELAEKLEVEIAIKRADWKKTVETQKSRIHAEFVQQKNFLVEEEQRQLQELEKDEREQLRILGEKEAKLAQQSQALQELISELDRRCHSSALELLQEVIIVLERSESWNLKDLDITSPELRSVCHVPGLKKMLRTCAVHITLDPDTANPWLILSEDRRQVRLGDTQQSIPGNEERFDSYPMVLGAQHFHSGKHYWEVDVTGKEAWDLGVCRDSVRRKGHFLLSSKSGFWTIWLWNKQKYEAGTYPQTPLHLQVPPCQVGIFLDYEAGMVSFYNITDHGSLIYSFSECAFTGPLRPFFSPGFNDGGKNTAPLTLCPLNIGSQGSTDY | Homo sapiens | Cytoplasm, Cytoplasmic vesicle, autophagosome, Nucleus, Cytoplasm, P-body, Cytoplasm, Stress granule | Low tissue specificity | {'Ciliated cells': '3.8', 'Basal respiratory cells': '6.8', 'Club cells': '5.8', 'Ionocytes': '3.7', 'Mucus glandular cells': '4.8', 'Serous glandular cells': '2.3', 'Gastric mucus-secreting cells': '8.8', 'Proximal enterocytes': '8.9', 'Paneth cells': '3.9', 'Distal enterocytes': '8.5', 'Intestinal goblet cells': '8.4', 'Exocrine glandular cells': '-0.716', 'Basal prostatic cells': '5.4', 'Prostatic glandular cells': '5.0', 'Breast glandular cells': '0.298', 'Breast myoepithelial cells': '0.351', 'Glandular and luminal cells': '5.9', 'Secretory cells': '8.4', 'Basal keratinocytes': '3.2', 'Suprabasal keratinocytes': '2.7', 'Basal squamous epithelial cells': '6.4', 'Squamous epithelial cells': '4.3', 'Alveolar cells type 1': '0.116', 'Alveolar cells type 2': '0.115', 'Salivary duct cells': '3.0', 'Ductal cells': '0.700', 'Hepatocytes': '0.503', 'Cholangiocytes': '11.4', 'Proximal tubular cells': '0.175', 'Distal tubular cells': '0.0', 'Collecting duct cells': '5.8', 'Mesothelial cells': '0.451', 'Sertoli cells': '0.479', 'Granulosa cells': '4.8', 'Enteroendocrine cells': '3.7', 'Pancreatic endocrine cells': '3.4', 'Leydig cells': '0.632', 'Excitatory neurons': '0.2', 'Inhibitory neurons': '0.1', 'Cone photoreceptor cells': '0.0', 'Rod photoreceptor cells': '0.0', 'Bipolar cells': '0.7', 'Horizontal cells': '0.6', 'Astrocytes': '0.0', 'Oligodendrocyte precursor cells': '0.9', 'Oligodendrocytes': '0.1', 'Microglial cells': '1.8', 'Muller glia cells': '2.4', 'Schwann cells': '0.099', 'Spermatogonia': '0.401', 'Spermatocytes': '-0.062', 'Early spermatids': '-0.578', 'Late spermatids': '-0.618', 'Oocytes': '1.5', 'Cytotrophoblasts': '6.6', 'Syncytiotrophoblasts': '9.8', 'Extravillous trophoblasts': '10.0', 'Endothelial cells': '7.8', 'Lymphatic endothelial cells': '6.9', 'Cardiomyocytes': '0.335', 'Skeletal myocytes': '-0.080', 'Smooth muscle cells': '6.3', 'Adipocytes': '8.3', 'Melanocytes': '0.101', 'Fibroblasts': '6.5', 'Peritubular cells': '0.579', 'Endometrial stromal cells': '4.5', 'Ovarian stromal cells': '6.7', 'Undifferentiated cells': '5.9', 'T-cells': '9.9', 'B-cells': '8.8', 'Plasma cells': '5.0', 'Nk-cells': '15.1', 'Granulocytes': '6.2', 'Monocytes': '7.8', 'Macrophages': '8.5', 'Hofbauer cells': '9.9', 'Kupffer cells': '10.3', 'Dendritic cells': '8.0', 'Langerhans cells': '0.466', 'Erythroid cells': '-0.084', 'Adipocytes (Subcutaneous)': '-0.368', 'Adipocytes (Visceral)': '-0.167', 'Breast glandular cells (progenitors)': '0.190', 'Adipocytes (Breast)': '-0.382', 'Colon enterocytes': '0.004', 'Colon enteroendocrine cells': '0.196', 'Enteric glia cells': '-0.129', 'Mitotic cells (Colon)': '0.005', 'Mitotic cells (Heart)': '0.486', 'Podocytes': '-0.114', 'Ascending Loop of Henle cells': '0.371', 'Intercalated cells': '-0.097', 'Cholangiocyte': '0.375', 'NK-cells (Liver)': '-0.278', 'Respiratory ciliated cells': '-0.022', 'Mitotic cells (Lung)': '0.157', 'NK-cells (Lung)': '0.110', 'B-cells (Lung)': '-0.155', 'Alpha cells': '0.333', 'Beta cells': '0.161', 'Prostate glandular cells': '-0.162', 'Prostate basal glandular cells': '0.286', 'Urothelial cells': '0.283', 'Keratinocyte (other)': '0.121', 'Keratinocyte (granular)': '-0.008', 'Hair cortex cells': '-0.113', 'Inner root sheath cells': '-0.069', 'Outer root sheath cells': '0.125', 'Sebaceous gland cells': '0.110', 'Eccrine sweat gland cells': '0.070', 'Adipocytes (Skin)': '0.019', 'Mitotic cells (Skin)': '0.236', 'Parietal cells': '-0.609', 'Chief cells': '-0.599', 'Gastric mucous cells': '-0.193', 'Gastric enteroendocrine cells': '-0.441', 'Mitotic cells (Stomach)': '0.261', 'Parafollicular cells': '-0.028', 'Thyroid glandular cells': '0.094', 'Mitotic cells (Thyroid)': '0.242', 'Adrenal cortex cells': '0.619', 'Adrenal medulla cells': '0.063', 'Mitotic cells (Adrenal gland)': '0.483', 'Minor salivary glandular cells': '0.582', 'Minor salivary gland ductal cells': '0.072', 'Minor salivary gland basal cells': '0.229', 'Mitotic cells (Minor salivary gland)': '0.376', 'Adipocytes (Minor salivary gland)': '0.211', 'Somatotropes': '-0.121', 'Lactotropes': '-0.287', 'Gonadotropes': '0.004', 'Corticotropes': '-0.352', 'Thyrotropes': '-0.054', 'Undifferentiated cells (Pituitary gland)': '0.486', 'Mitotic cells (Spleen)': '-0.016', 'Platelets': '0.115', 'Erythrocytes': '0.098', 'Hematopoietic stem cells': '0.042', 'B-cells (Spleen)': '0.028', 'NK-cells (Spleen)': '0.157', 'Amygdala excitatory': '0.1', 'Cerebellar inhibitory': '0.2', 'Cge interneuron': '0.3', 'Deep-layer corticothalamic and 6b': '0.3', 'Deep-layer intratelencephalic': '0.1', 'Deep-layer near-projecting': '0.1', 'Eccentric medium spiny neuron': '0.4', 'Hippocampal ca1-3': '0.5', 'Hippocampal ca4': '0.1', 'Hippocampal dentate gyrus': '0.3', 'Lamp5-lhx6 and chandelier': '0.3', 'Lower rhombic lip': '0.2', 'Mammillary body': '0.4', 'Medium spiny neuron': '0.6', 'Mge interneuron': '0.1', 'Midbrain-derived inhibitory': '0.6', 'Miscellaneous': '0.6', 'Splatter': '0.5', 'Thalamic excitatory': '1.3', 'Upper rhombic lip': '0.1', 'Upper-layer intratelencephalic': '0.1', 'Astrocyte': '1.5', 'Bergmann glia': '1.5', 'Central nervous system macrophage': '6.0', 'Choroid plexus epithelial cell': '2.9', 'Committed oligodendrocyte precursor': '1.0', 'Ependymal cell': '1.3', 'Oligodendrocyte': '0.1', 'Oligodendrocyte precursor cell': '2.3', 'Endothelial cell': '6.4', 'Pericyte': '5.3', 'Vascular associated smooth muscle cell': '3.1', 'Fibroblast': '5.3', 'Leukocyte': '7.4', 'Basophil': '107.0', 'Eosinophil': '312.5', 'Neutrophil': '496.9', 'Classical monocyte': '25.8', 'Non-classical monocyte': '66.1', 'Intermediate monocyte': '117.0', 'T-reg': '72.1', 'GdT-cell': '89.5', 'MAIT T-cell': '61.2', 'Memory CD4 T-cell': '76.8', 'Naive CD4 T-cell': '47.0', 'Memory CD8 T-cell': '81.1', 'Naive CD8 T-cell': '43.5', 'Memory B-cell': '50.4', 'Naive B-cell': '38.5', 'Plasmacytoid DC': '47.5', 'Myeloid DC': '92.2', 'NK-cell': '88.9', 'Total PBMC': '83.8', 'Vd2 gdTCR': '67.8', 'Memory CD4 T-cell Th1\\/Th17': '48.0', 'Memory CD4 T-cell Th17': '54.6', 'Memory CD4 T-cell Th2': '54.8', 'Non-Vd2 gdTCR': '73.7', 'Memory CD4 T-cell Th1': '58.8', 'Memory CD4 T-cell TFH': '61.9', 'Terminal effector memory CD4 T-cell': '72.8', 'Central memory CD8 T-cell': '59.9', 'Effector memory CD8 T-cell': '90.7', 'Terminal effector memory CD8 T-cell': '75.8', 'Non-switched memory B-cell': '52.6', 'Plasmablast': '62.3', 'Switched memory B-cell': '55.8', 'Exhausted memory B-cell': '52.1', 'Progenitor cell': '44.7', 'Memory T-reg': '82.4', 'Naive CD4 T-cell activated': '133.9', 'Naive CD8 T-cell activated': '163.4', 'Naive T-reg': '54.7'} | 2IWG, 5JPX, 5OLM, 6FGA, 6S53, 7BBD, 8A58 | {'Adipose Tissue': 21.42795099667774, 'Adrenal Gland': 16.707763565891472, 'Bladder': 21.861904761904764, 'Blood': 61.11958557588805, 'Blood Vessel': 22.62928389513109, 'Brain': 4.305000416351249, 'Breast': 20.001740740740743, 'Cervix Uteri': 26.420526315789473, 'Colon': 23.40817458279846, 'Esophagus': 21.74157577854671, 'Fallopian Tube': 25.39, 'Heart': 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CDKN1B, IRF3, IRF8, MNI | mono, 63 | null | UBE2D2, UBE2D1, UBE2E1, UBE2E2 | Homotrimer | null | 90.718042 | 0.406716 | 90.718042 | 0.406716 | 1,674 |
P19474 | P34897 | 30367038 | UbiBrowser | TRIM21 | MASAARLTMMWEEVTCPICLDPFVEPVSIECGHSFCQECISQVGKGGGSVCPVCRQRFLLKNLRPNRQLANMVNNLKEISQEAREGTQGERCAVHGERLHLFCEKDGKALCWVCAQSRKHRDHAMVPLEEAAQEYQEKLQVALGELRRKQELAEKLEVEIAIKRADWKKTVETQKSRIHAEFVQQKNFLVEEEQRQLQELEKDEREQLRILGEKEAKLAQQSQALQELISELDRRCHSSALELLQEVIIVLERSESWNLKDLDITSPELRSVCHVPGLKKMLRTCAVHITLDPDTANPWLILSEDRRQVRLGDTQQSIPGNEERFDSYPMVLGAQHFHSGKHYWEVDVTGKEAWDLGVCRDSVRRKGHFLLSSKSGFWTIWLWNKQKYEAGTYPQTPLHLQVPPCQVGIFLDYEAGMVSFYNITDHGSLIYSFSECAFTGPLRPFFSPGFNDGGKNTAPLTLCPLNIGSQGSTDY | Homo sapiens | Cytoplasm, Cytoplasmic vesicle, autophagosome, Nucleus, Cytoplasm, P-body, Cytoplasm, Stress granule | Low tissue specificity | {'Ciliated cells': '3.8', 'Basal respiratory cells': '6.8', 'Club cells': '5.8', 'Ionocytes': '3.7', 'Mucus glandular cells': '4.8', 'Serous glandular cells': '2.3', 'Gastric mucus-secreting cells': '8.8', 'Proximal enterocytes': '8.9', 'Paneth cells': '3.9', 'Distal enterocytes': '8.5', 'Intestinal goblet cells': '8.4', 'Exocrine glandular cells': '-0.716', 'Basal prostatic cells': '5.4', 'Prostatic glandular cells': '5.0', 'Breast glandular cells': '0.298', 'Breast myoepithelial cells': '0.351', 'Glandular and luminal cells': '5.9', 'Secretory cells': '8.4', 'Basal keratinocytes': '3.2', 'Suprabasal keratinocytes': '2.7', 'Basal squamous epithelial cells': '6.4', 'Squamous epithelial cells': '4.3', 'Alveolar cells type 1': '0.116', 'Alveolar cells type 2': '0.115', 'Salivary duct cells': '3.0', 'Ductal cells': '0.700', 'Hepatocytes': '0.503', 'Cholangiocytes': '11.4', 'Proximal tubular cells': '0.175', 'Distal tubular cells': '0.0', 'Collecting duct cells': '5.8', 'Mesothelial cells': '0.451', 'Sertoli cells': '0.479', 'Granulosa cells': '4.8', 'Enteroendocrine cells': '3.7', 'Pancreatic endocrine cells': '3.4', 'Leydig cells': '0.632', 'Excitatory neurons': '0.2', 'Inhibitory neurons': '0.1', 'Cone photoreceptor cells': '0.0', 'Rod photoreceptor cells': '0.0', 'Bipolar cells': '0.7', 'Horizontal cells': '0.6', 'Astrocytes': '0.0', 'Oligodendrocyte precursor cells': '0.9', 'Oligodendrocytes': '0.1', 'Microglial cells': '1.8', 'Muller glia cells': '2.4', 'Schwann cells': '0.099', 'Spermatogonia': '0.401', 'Spermatocytes': '-0.062', 'Early spermatids': '-0.578', 'Late spermatids': '-0.618', 'Oocytes': '1.5', 'Cytotrophoblasts': '6.6', 'Syncytiotrophoblasts': '9.8', 'Extravillous trophoblasts': '10.0', 'Endothelial cells': '7.8', 'Lymphatic endothelial cells': '6.9', 'Cardiomyocytes': '0.335', 'Skeletal myocytes': '-0.080', 'Smooth muscle cells': '6.3', 'Adipocytes': '8.3', 'Melanocytes': '0.101', 'Fibroblasts': '6.5', 'Peritubular cells': '0.579', 'Endometrial stromal cells': '4.5', 'Ovarian stromal cells': '6.7', 'Undifferentiated cells': '5.9', 'T-cells': '9.9', 'B-cells': '8.8', 'Plasma cells': '5.0', 'Nk-cells': '15.1', 'Granulocytes': '6.2', 'Monocytes': '7.8', 'Macrophages': '8.5', 'Hofbauer cells': '9.9', 'Kupffer cells': '10.3', 'Dendritic cells': '8.0', 'Langerhans cells': '0.466', 'Erythroid cells': '-0.084', 'Adipocytes (Subcutaneous)': '-0.368', 'Adipocytes (Visceral)': '-0.167', 'Breast glandular cells (progenitors)': '0.190', 'Adipocytes (Breast)': '-0.382', 'Colon enterocytes': '0.004', 'Colon enteroendocrine cells': '0.196', 'Enteric glia cells': '-0.129', 'Mitotic cells (Colon)': '0.005', 'Mitotic cells (Heart)': '0.486', 'Podocytes': '-0.114', 'Ascending Loop of Henle cells': '0.371', 'Intercalated cells': '-0.097', 'Cholangiocyte': '0.375', 'NK-cells (Liver)': '-0.278', 'Respiratory ciliated cells': '-0.022', 'Mitotic cells (Lung)': '0.157', 'NK-cells (Lung)': '0.110', 'B-cells (Lung)': '-0.155', 'Alpha cells': '0.333', 'Beta cells': '0.161', 'Prostate glandular cells': '-0.162', 'Prostate basal glandular cells': '0.286', 'Urothelial cells': '0.283', 'Keratinocyte (other)': '0.121', 'Keratinocyte (granular)': '-0.008', 'Hair cortex cells': '-0.113', 'Inner root sheath cells': '-0.069', 'Outer root sheath cells': '0.125', 'Sebaceous gland cells': '0.110', 'Eccrine sweat gland cells': '0.070', 'Adipocytes (Skin)': '0.019', 'Mitotic cells (Skin)': '0.236', 'Parietal cells': '-0.609', 'Chief cells': '-0.599', 'Gastric mucous cells': '-0.193', 'Gastric enteroendocrine cells': '-0.441', 'Mitotic cells (Stomach)': '0.261', 'Parafollicular cells': '-0.028', 'Thyroid glandular cells': '0.094', 'Mitotic cells (Thyroid)': '0.242', 'Adrenal cortex cells': '0.619', 'Adrenal medulla cells': '0.063', 'Mitotic cells (Adrenal gland)': '0.483', 'Minor salivary glandular cells': '0.582', 'Minor salivary gland ductal cells': '0.072', 'Minor salivary gland basal cells': '0.229', 'Mitotic cells (Minor salivary gland)': '0.376', 'Adipocytes (Minor salivary gland)': '0.211', 'Somatotropes': '-0.121', 'Lactotropes': '-0.287', 'Gonadotropes': '0.004', 'Corticotropes': '-0.352', 'Thyrotropes': '-0.054', 'Undifferentiated cells (Pituitary gland)': '0.486', 'Mitotic cells (Spleen)': '-0.016', 'Platelets': '0.115', 'Erythrocytes': '0.098', 'Hematopoietic stem cells': '0.042', 'B-cells (Spleen)': '0.028', 'NK-cells (Spleen)': '0.157', 'Amygdala excitatory': '0.1', 'Cerebellar inhibitory': '0.2', 'Cge interneuron': '0.3', 'Deep-layer corticothalamic and 6b': '0.3', 'Deep-layer intratelencephalic': '0.1', 'Deep-layer near-projecting': '0.1', 'Eccentric medium spiny neuron': '0.4', 'Hippocampal ca1-3': '0.5', 'Hippocampal ca4': '0.1', 'Hippocampal dentate gyrus': '0.3', 'Lamp5-lhx6 and chandelier': '0.3', 'Lower rhombic lip': '0.2', 'Mammillary body': '0.4', 'Medium spiny neuron': '0.6', 'Mge interneuron': '0.1', 'Midbrain-derived inhibitory': '0.6', 'Miscellaneous': '0.6', 'Splatter': '0.5', 'Thalamic excitatory': '1.3', 'Upper rhombic lip': '0.1', 'Upper-layer intratelencephalic': '0.1', 'Astrocyte': '1.5', 'Bergmann glia': '1.5', 'Central nervous system macrophage': '6.0', 'Choroid plexus epithelial cell': '2.9', 'Committed oligodendrocyte precursor': '1.0', 'Ependymal cell': '1.3', 'Oligodendrocyte': '0.1', 'Oligodendrocyte precursor cell': '2.3', 'Endothelial cell': '6.4', 'Pericyte': '5.3', 'Vascular associated smooth muscle cell': '3.1', 'Fibroblast': '5.3', 'Leukocyte': '7.4', 'Basophil': '107.0', 'Eosinophil': '312.5', 'Neutrophil': '496.9', 'Classical monocyte': '25.8', 'Non-classical monocyte': '66.1', 'Intermediate monocyte': '117.0', 'T-reg': '72.1', 'GdT-cell': '89.5', 'MAIT T-cell': '61.2', 'Memory CD4 T-cell': '76.8', 'Naive CD4 T-cell': '47.0', 'Memory CD8 T-cell': '81.1', 'Naive CD8 T-cell': '43.5', 'Memory B-cell': '50.4', 'Naive B-cell': '38.5', 'Plasmacytoid DC': '47.5', 'Myeloid DC': '92.2', 'NK-cell': '88.9', 'Total PBMC': '83.8', 'Vd2 gdTCR': '67.8', 'Memory CD4 T-cell Th1\\/Th17': '48.0', 'Memory CD4 T-cell Th17': '54.6', 'Memory CD4 T-cell Th2': '54.8', 'Non-Vd2 gdTCR': '73.7', 'Memory CD4 T-cell Th1': '58.8', 'Memory CD4 T-cell TFH': '61.9', 'Terminal effector memory CD4 T-cell': '72.8', 'Central memory CD8 T-cell': '59.9', 'Effector memory CD8 T-cell': '90.7', 'Terminal effector memory CD8 T-cell': '75.8', 'Non-switched memory B-cell': '52.6', 'Plasmablast': '62.3', 'Switched memory B-cell': '55.8', 'Exhausted memory B-cell': '52.1', 'Progenitor cell': '44.7', 'Memory T-reg': '82.4', 'Naive CD4 T-cell activated': '133.9', 'Naive CD8 T-cell activated': '163.4', 'Naive T-reg': '54.7'} | 2IWG, 5JPX, 5OLM, 6FGA, 6S53, 7BBD, 8A58 | {'Adipose Tissue': 21.42795099667774, 'Adrenal Gland': 16.707763565891472, 'Bladder': 21.861904761904764, 'Blood': 61.11958557588805, 'Blood Vessel': 22.62928389513109, 'Brain': 4.305000416351249, 'Breast': 20.001740740740743, 'Cervix Uteri': 26.420526315789473, 'Colon': 23.40817458279846, 'Esophagus': 21.74157577854671, 'Fallopian Tube': 25.39, 'Heart': 6.66628106852497, 'Kidney': 13.61479775280899, 'Liver': 10.388, 'Lung': 32.00464878892734, 'Muscle': 3.944284806973848, 'Nerve': 25.39305008077545, 'Ovary': 30.51811111111111, 'Pancreas': 6.808080182926829, 'Pituitary': 12.995699646643107, 'Prostate': 21.00597551020408, 'Salivary Gland': 16.434148148148147, 'Skin': 17.851811498065228, 'Small Intestine': 28.907085561497325, 'Spleen': 50.16024896265561, 'Stomach': 19.072721448467966, 'Testis': 6.377013850415512, 'Thyroid': 21.553307810107196, 'Uterus': 29.83549295774648, 'Vagina': 21.551141025641027} | SHMT2 | MLYFSLFWAARPLQRCGQLVRMAIRAQHSNAAQTQTGEANRGWTGQESLSDSDPEMWELLQREKDRQCRGLELIASENFCSRAALEALGSCLNNKYSEGYPGKRYYGGAEVVDEIELLCQRRALEAFDLDPAQWGVNVQPYSGSPANLAVYTALLQPHDRIMGLDLPDGGHLTHGYMSDVKRISATSIFFESMPYKLNPKTGLIDYNQLALTARLFRPRLIIAGTSAYARLIDYARMREVCDEVKAHLLADMAHISGLVAAKVIPSPFKHADIVTTTTHKTLRGARSGLIFYRKGVKAVDPKTGREIPYTFEDRINFAVFPSLQGGPHNHAIAAVAVALKQACTPMFREYSLQVLKNARAMADALLERGYSLVSGGTDNHLVLVDLRPKGLDGARAERVLELVSITANKNTCPGDRSAITPGGLRLGAPALTSRQFREDDFRRVVDFIDEGVNIGLEVKSKTAKLQDFKSFLLKDSETSQRLANLRQRVEQFARAFPMPGFDEH | Homo sapiens | Mitochondrion, Mitochondrion matrix, mitochondrion nucleoid, Mitochondrion inner membrane, Cytoplasm, Nucleus | Tissue enhanced (liver) | {'Ciliated cells': '10.1', 'Basal respiratory cells': '42.5', 'Club cells': '21.1', 'Ionocytes': '21.7', 'Mucus glandular cells': '15.7', 'Serous glandular cells': '24.8', 'Gastric mucus-secreting cells': '24.2', 'Proximal enterocytes': '14.5', 'Paneth cells': '21.0', 'Distal enterocytes': '11.0', 'Intestinal goblet cells': '18.8', 'Exocrine glandular cells': '-0.671', 'Basal prostatic cells': '9.8', 'Prostatic glandular cells': '12.7', 'Breast glandular cells': '0.330', 'Breast myoepithelial cells': '0.012', 'Glandular and luminal cells': '11.6', 'Secretory cells': '27.0', 'Basal keratinocytes': '38.1', 'Suprabasal keratinocytes': '33.1', 'Basal squamous epithelial cells': '54.5', 'Squamous epithelial cells': '46.2', 'Alveolar cells type 1': '-0.337', 'Alveolar cells type 2': '0.171', 'Salivary duct cells': '20.5', 'Ductal cells': '0.366', 'Hepatocytes': '0.421', 'Cholangiocytes': '21.0', 'Proximal tubular cells': '0.363', 'Distal tubular cells': '3.1', 'Collecting duct cells': '5.8', 'Mesothelial cells': '0.272', 'Sertoli cells': '0.597', 'Granulosa cells': '20.8', 'Enteroendocrine cells': '17.5', 'Pancreatic endocrine cells': '49.2', 'Leydig cells': '0.688', 'Excitatory neurons': '3.6', 'Inhibitory neurons': '3.1', 'Cone photoreceptor cells': '5.1', 'Rod photoreceptor cells': '2.2', 'Bipolar cells': '7.1', 'Horizontal cells': '7.6', 'Astrocytes': '4.0', 'Oligodendrocyte precursor cells': '3.8', 'Oligodendrocytes': '2.2', 'Microglial cells': '3.6', 'Muller glia cells': '46.0', 'Schwann cells': '0.006', 'Spermatogonia': '0.447', 'Spermatocytes': '-0.011', 'Early spermatids': '-0.618', 'Late spermatids': '-0.692', 'Oocytes': '21.3', 'Cytotrophoblasts': '57.1', 'Syncytiotrophoblasts': '34.1', 'Extravillous trophoblasts': '49.6', 'Endothelial cells': '16.3', 'Lymphatic endothelial cells': '8.4', 'Cardiomyocytes': '0.461', 'Skeletal myocytes': '-0.339', 'Smooth muscle cells': '23.2', 'Adipocytes': '9.2', 'Melanocytes': '0.183', 'Fibroblasts': '31.0', 'Peritubular cells': '0.535', 'Endometrial stromal cells': '23.0', 'Ovarian stromal cells': '17.8', 'Undifferentiated cells': '58.5', 'T-cells': '20.0', 'B-cells': '49.8', 'Plasma cells': '90.5', 'Nk-cells': '16.8', 'Granulocytes': '23.6', 'Monocytes': '21.5', 'Macrophages': '22.5', 'Hofbauer cells': '44.2', 'Kupffer cells': '34.9', 'Dendritic cells': '11.1', 'Langerhans cells': '0.031', 'Erythroid cells': '-0.026', 'Adipocytes (Subcutaneous)': '-0.158', 'Adipocytes (Visceral)': '-0.204', 'Breast glandular cells (progenitors)': '0.213', 'Adipocytes (Breast)': '-0.182', 'Colon enterocytes': '0.117', 'Colon enteroendocrine cells': '-0.013', 'Enteric glia cells': '-0.295', 'Mitotic cells (Colon)': '0.293', 'Mitotic cells (Heart)': '0.505', 'Podocytes': '0.054', 'Ascending Loop of Henle cells': '0.232', 'Intercalated cells': '0.012', 'Cholangiocyte': '0.237', 'NK-cells (Liver)': '-0.401', 'Respiratory ciliated cells': '-0.135', 'Mitotic cells (Lung)': '0.341', 'NK-cells (Lung)': '-0.365', 'B-cells (Lung)': '-0.223', 'Alpha cells': '0.252', 'Beta cells': '0.097', 'Prostate glandular cells': '0.043', 'Prostate basal glandular cells': '0.380', 'Urothelial cells': '0.265', 'Keratinocyte (other)': '0.163', 'Keratinocyte (granular)': '-0.231', 'Hair cortex cells': '0.110', 'Inner root sheath cells': '0.176', 'Outer root sheath cells': '0.197', 'Sebaceous gland cells': '-0.025', 'Eccrine sweat gland cells': '-0.068', 'Adipocytes (Skin)': '-0.155', 'Mitotic cells (Skin)': '0.415', 'Parietal cells': '0.200', 'Chief cells': '0.535', 'Gastric mucous cells': '0.430', 'Gastric enteroendocrine cells': '0.443', 'Mitotic cells (Stomach)': '0.415', 'Parafollicular cells': '-0.051', 'Thyroid glandular cells': '0.022', 'Mitotic cells (Thyroid)': '0.199', 'Adrenal cortex cells': '0.451', 'Adrenal medulla cells': '-0.008', 'Mitotic cells (Adrenal gland)': '0.487', 'Minor salivary glandular cells': '0.287', 'Minor salivary gland ductal cells': '-0.043', 'Minor salivary gland basal cells': '0.168', 'Mitotic cells (Minor 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P19474 | P35232 | 30886235 | UbiBrowser | TRIM21 | MASAARLTMMWEEVTCPICLDPFVEPVSIECGHSFCQECISQVGKGGGSVCPVCRQRFLLKNLRPNRQLANMVNNLKEISQEAREGTQGERCAVHGERLHLFCEKDGKALCWVCAQSRKHRDHAMVPLEEAAQEYQEKLQVALGELRRKQELAEKLEVEIAIKRADWKKTVETQKSRIHAEFVQQKNFLVEEEQRQLQELEKDEREQLRILGEKEAKLAQQSQALQELISELDRRCHSSALELLQEVIIVLERSESWNLKDLDITSPELRSVCHVPGLKKMLRTCAVHITLDPDTANPWLILSEDRRQVRLGDTQQSIPGNEERFDSYPMVLGAQHFHSGKHYWEVDVTGKEAWDLGVCRDSVRRKGHFLLSSKSGFWTIWLWNKQKYEAGTYPQTPLHLQVPPCQVGIFLDYEAGMVSFYNITDHGSLIYSFSECAFTGPLRPFFSPGFNDGGKNTAPLTLCPLNIGSQGSTDY | Homo sapiens | Cytoplasm, Cytoplasmic vesicle, autophagosome, Nucleus, Cytoplasm, P-body, Cytoplasm, Stress granule | Low tissue specificity | {'Ciliated cells': '3.8', 'Basal respiratory cells': '6.8', 'Club cells': '5.8', 'Ionocytes': '3.7', 'Mucus glandular cells': '4.8', 'Serous glandular cells': '2.3', 'Gastric mucus-secreting cells': '8.8', 'Proximal enterocytes': '8.9', 'Paneth cells': '3.9', 'Distal enterocytes': '8.5', 'Intestinal goblet cells': '8.4', 'Exocrine glandular cells': '-0.716', 'Basal prostatic cells': '5.4', 'Prostatic glandular cells': '5.0', 'Breast glandular cells': '0.298', 'Breast myoepithelial cells': '0.351', 'Glandular and luminal cells': '5.9', 'Secretory cells': '8.4', 'Basal keratinocytes': '3.2', 'Suprabasal keratinocytes': '2.7', 'Basal squamous epithelial cells': '6.4', 'Squamous epithelial cells': '4.3', 'Alveolar cells type 1': '0.116', 'Alveolar cells type 2': '0.115', 'Salivary duct cells': '3.0', 'Ductal cells': '0.700', 'Hepatocytes': '0.503', 'Cholangiocytes': '11.4', 'Proximal tubular cells': '0.175', 'Distal tubular cells': '0.0', 'Collecting duct cells': '5.8', 'Mesothelial cells': '0.451', 'Sertoli cells': '0.479', 'Granulosa cells': '4.8', 'Enteroendocrine cells': '3.7', 'Pancreatic endocrine cells': '3.4', 'Leydig cells': '0.632', 'Excitatory neurons': '0.2', 'Inhibitory neurons': '0.1', 'Cone photoreceptor cells': '0.0', 'Rod photoreceptor cells': '0.0', 'Bipolar cells': '0.7', 'Horizontal cells': '0.6', 'Astrocytes': '0.0', 'Oligodendrocyte precursor cells': '0.9', 'Oligodendrocytes': '0.1', 'Microglial cells': '1.8', 'Muller glia cells': '2.4', 'Schwann cells': '0.099', 'Spermatogonia': '0.401', 'Spermatocytes': '-0.062', 'Early spermatids': '-0.578', 'Late spermatids': '-0.618', 'Oocytes': '1.5', 'Cytotrophoblasts': '6.6', 'Syncytiotrophoblasts': '9.8', 'Extravillous trophoblasts': '10.0', 'Endothelial cells': '7.8', 'Lymphatic endothelial cells': '6.9', 'Cardiomyocytes': '0.335', 'Skeletal myocytes': '-0.080', 'Smooth muscle cells': '6.3', 'Adipocytes': '8.3', 'Melanocytes': '0.101', 'Fibroblasts': '6.5', 'Peritubular cells': '0.579', 'Endometrial stromal cells': '4.5', 'Ovarian stromal cells': '6.7', 'Undifferentiated cells': '5.9', 'T-cells': '9.9', 'B-cells': '8.8', 'Plasma cells': '5.0', 'Nk-cells': '15.1', 'Granulocytes': '6.2', 'Monocytes': '7.8', 'Macrophages': '8.5', 'Hofbauer cells': '9.9', 'Kupffer cells': '10.3', 'Dendritic cells': '8.0', 'Langerhans cells': '0.466', 'Erythroid cells': '-0.084', 'Adipocytes (Subcutaneous)': '-0.368', 'Adipocytes (Visceral)': '-0.167', 'Breast glandular cells (progenitors)': '0.190', 'Adipocytes (Breast)': '-0.382', 'Colon enterocytes': '0.004', 'Colon enteroendocrine cells': '0.196', 'Enteric glia cells': '-0.129', 'Mitotic cells (Colon)': '0.005', 'Mitotic cells (Heart)': '0.486', 'Podocytes': '-0.114', 'Ascending Loop of Henle cells': '0.371', 'Intercalated cells': '-0.097', 'Cholangiocyte': '0.375', 'NK-cells (Liver)': '-0.278', 'Respiratory ciliated cells': '-0.022', 'Mitotic cells (Lung)': '0.157', 'NK-cells (Lung)': '0.110', 'B-cells (Lung)': '-0.155', 'Alpha cells': '0.333', 'Beta cells': '0.161', 'Prostate glandular cells': '-0.162', 'Prostate basal glandular cells': '0.286', 'Urothelial cells': '0.283', 'Keratinocyte (other)': '0.121', 'Keratinocyte (granular)': '-0.008', 'Hair cortex cells': '-0.113', 'Inner root sheath cells': '-0.069', 'Outer root sheath cells': '0.125', 'Sebaceous gland cells': '0.110', 'Eccrine sweat gland cells': '0.070', 'Adipocytes (Skin)': '0.019', 'Mitotic cells (Skin)': '0.236', 'Parietal cells': '-0.609', 'Chief cells': '-0.599', 'Gastric mucous cells': '-0.193', 'Gastric enteroendocrine cells': '-0.441', 'Mitotic cells (Stomach)': '0.261', 'Parafollicular cells': '-0.028', 'Thyroid glandular cells': '0.094', 'Mitotic cells (Thyroid)': '0.242', 'Adrenal cortex cells': '0.619', 'Adrenal medulla cells': '0.063', 'Mitotic cells (Adrenal gland)': '0.483', 'Minor salivary glandular cells': '0.582', 'Minor salivary gland ductal cells': '0.072', 'Minor salivary gland basal cells': '0.229', 'Mitotic cells (Minor salivary gland)': '0.376', 'Adipocytes (Minor salivary gland)': '0.211', 'Somatotropes': '-0.121', 'Lactotropes': '-0.287', 'Gonadotropes': '0.004', 'Corticotropes': '-0.352', 'Thyrotropes': '-0.054', 'Undifferentiated cells (Pituitary gland)': '0.486', 'Mitotic cells (Spleen)': '-0.016', 'Platelets': '0.115', 'Erythrocytes': '0.098', 'Hematopoietic stem cells': '0.042', 'B-cells (Spleen)': '0.028', 'NK-cells (Spleen)': '0.157', 'Amygdala excitatory': '0.1', 'Cerebellar inhibitory': '0.2', 'Cge interneuron': '0.3', 'Deep-layer corticothalamic and 6b': '0.3', 'Deep-layer intratelencephalic': '0.1', 'Deep-layer near-projecting': '0.1', 'Eccentric medium spiny neuron': '0.4', 'Hippocampal ca1-3': '0.5', 'Hippocampal ca4': '0.1', 'Hippocampal dentate gyrus': '0.3', 'Lamp5-lhx6 and chandelier': '0.3', 'Lower rhombic lip': '0.2', 'Mammillary body': '0.4', 'Medium spiny neuron': '0.6', 'Mge interneuron': '0.1', 'Midbrain-derived inhibitory': '0.6', 'Miscellaneous': '0.6', 'Splatter': '0.5', 'Thalamic excitatory': '1.3', 'Upper rhombic lip': '0.1', 'Upper-layer intratelencephalic': '0.1', 'Astrocyte': '1.5', 'Bergmann glia': '1.5', 'Central nervous system macrophage': '6.0', 'Choroid plexus epithelial cell': '2.9', 'Committed oligodendrocyte precursor': '1.0', 'Ependymal cell': '1.3', 'Oligodendrocyte': '0.1', 'Oligodendrocyte precursor cell': '2.3', 'Endothelial cell': '6.4', 'Pericyte': '5.3', 'Vascular associated smooth muscle cell': '3.1', 'Fibroblast': '5.3', 'Leukocyte': '7.4', 'Basophil': '107.0', 'Eosinophil': '312.5', 'Neutrophil': '496.9', 'Classical monocyte': '25.8', 'Non-classical monocyte': '66.1', 'Intermediate monocyte': '117.0', 'T-reg': '72.1', 'GdT-cell': '89.5', 'MAIT T-cell': '61.2', 'Memory CD4 T-cell': '76.8', 'Naive CD4 T-cell': '47.0', 'Memory CD8 T-cell': '81.1', 'Naive CD8 T-cell': '43.5', 'Memory B-cell': '50.4', 'Naive B-cell': '38.5', 'Plasmacytoid DC': '47.5', 'Myeloid DC': '92.2', 'NK-cell': '88.9', 'Total PBMC': '83.8', 'Vd2 gdTCR': '67.8', 'Memory CD4 T-cell Th1\\/Th17': '48.0', 'Memory CD4 T-cell Th17': '54.6', 'Memory CD4 T-cell Th2': '54.8', 'Non-Vd2 gdTCR': '73.7', 'Memory CD4 T-cell Th1': '58.8', 'Memory CD4 T-cell TFH': '61.9', 'Terminal effector memory CD4 T-cell': '72.8', 'Central memory CD8 T-cell': '59.9', 'Effector memory CD8 T-cell': '90.7', 'Terminal effector memory CD8 T-cell': '75.8', 'Non-switched memory B-cell': '52.6', 'Plasmablast': '62.3', 'Switched memory B-cell': '55.8', 'Exhausted memory B-cell': '52.1', 'Progenitor cell': '44.7', 'Memory T-reg': '82.4', 'Naive CD4 T-cell activated': '133.9', 'Naive CD8 T-cell activated': '163.4', 'Naive T-reg': '54.7'} | 2IWG, 5JPX, 5OLM, 6FGA, 6S53, 7BBD, 8A58 | {'Adipose Tissue': 21.42795099667774, 'Adrenal Gland': 16.707763565891472, 'Bladder': 21.861904761904764, 'Blood': 61.11958557588805, 'Blood Vessel': 22.62928389513109, 'Brain': 4.305000416351249, 'Breast': 20.001740740740743, 'Cervix Uteri': 26.420526315789473, 'Colon': 23.40817458279846, 'Esophagus': 21.74157577854671, 'Fallopian Tube': 25.39, 'Heart': 6.66628106852497, 'Kidney': 13.61479775280899, 'Liver': 10.388, 'Lung': 32.00464878892734, 'Muscle': 3.944284806973848, 'Nerve': 25.39305008077545, 'Ovary': 30.51811111111111, 'Pancreas': 6.808080182926829, 'Pituitary': 12.995699646643107, 'Prostate': 21.00597551020408, 'Salivary Gland': 16.434148148148147, 'Skin': 17.851811498065228, 'Small Intestine': 28.907085561497325, 'Spleen': 50.16024896265561, 'Stomach': 19.072721448467966, 'Testis': 6.377013850415512, 'Thyroid': 21.553307810107196, 'Uterus': 29.83549295774648, 'Vagina': 21.551141025641027} | PHB1 | MAAKVFESIGKFGLALAVAGGVVNSALYNVDAGHRAVIFDRFRGVQDIVVGEGTHFLIPWVQKPIIFDCRSRPRNVPVITGSKDLQNVNITLRILFRPVASQLPRIFTSIGEDYDERVLPSITTEILKSVVARFDAGELITQRELVSRQVSDDLTERAATFGLILDDVSLTHLTFGKEFTEAVEAKQVAQQEAERARFVVEKAEQQKKAAIISAEGDSKAAELIANSLATAGDGLIELRKLEAAEDIAYQLSRSRNITYLPAGQSVLLQLPQ | Homo sapiens | Mitochondrion inner membrane, Nucleus, Cytoplasm, Cell membrane | Low tissue specificity | {'Ciliated cells': '79.5', 'Basal respiratory cells': '177.9', 'Club cells': '124.0', 'Ionocytes': '130.0', 'Mucus glandular cells': '136.4', 'Serous glandular cells': '218.9', 'Gastric mucus-secreting cells': '71.9', 'Proximal enterocytes': '149.9', 'Paneth cells': '170.8', 'Distal enterocytes': '240.4', 'Intestinal goblet cells': '208.4', 'Exocrine glandular cells': '-0.673', 'Basal prostatic cells': '103.6', 'Prostatic glandular cells': '110.3', 'Breast glandular cells': '0.168', 'Breast myoepithelial cells': '-0.135', 'Glandular and luminal cells': '141.1', 'Secretory cells': '148.3', 'Basal keratinocytes': '129.9', 'Suprabasal keratinocytes': '139.4', 'Basal squamous epithelial cells': '77.6', 'Squamous epithelial cells': '109.2', 'Alveolar cells type 1': '-0.095', 'Alveolar cells type 2': '0.314', 'Salivary duct cells': '97.3', 'Ductal cells': '0.603', 'Hepatocytes': '0.580', 'Cholangiocytes': '95.4', 'Proximal tubular cells': '0.444', 'Distal tubular cells': '341.2', 'Collecting duct cells': '89.5', 'Mesothelial cells': '0.019', 'Sertoli cells': '0.746', 'Granulosa cells': '94.9', 'Enteroendocrine cells': '215.7', 'Pancreatic endocrine cells': '205.5', 'Leydig cells': '0.699', 'Excitatory neurons': '7.6', 'Inhibitory neurons': '9.6', 'Cone photoreceptor cells': '61.2', 'Rod photoreceptor cells': '30.9', 'Bipolar cells': '39.8', 'Horizontal cells': '29.6', 'Astrocytes': '8.4', 'Oligodendrocyte precursor cells': '10.4', 'Oligodendrocytes': '14.3', 'Microglial cells': '1.8', 'Muller glia cells': '77.0', 'Schwann cells': '-0.009', 'Spermatogonia': '0.633', 'Spermatocytes': '0.169', 'Early spermatids': '-0.570', 'Late spermatids': '-0.644', 'Oocytes': '186.0', 'Cytotrophoblasts': '252.6', 'Syncytiotrophoblasts': '143.4', 'Extravillous trophoblasts': '288.6', 'Endothelial cells': '94.5', 'Lymphatic endothelial cells': '97.9', 'Cardiomyocytes': '0.741', 'Skeletal myocytes': '-0.042', 'Smooth muscle cells': '95.9', 'Adipocytes': '85.0', 'Melanocytes': '-0.009', 'Fibroblasts': '102.2', 'Peritubular cells': '0.509', 'Endometrial stromal cells': '90.3', 'Ovarian stromal cells': '114.2', 'Undifferentiated cells': '307.8', 'T-cells': '71.9', 'B-cells': '75.4', 'Plasma cells': '119.7', 'Nk-cells': '75.8', 'Granulocytes': '87.0', 'Monocytes': '44.7', 'Macrophages': 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0.17, 0.72, 0.36, 0.0, 0.08, 0.67, 0.02, 0.22, 0.65, 0.77, 0.18, 0.21, 0.57, 0.65, 0.1, 0.35, 0.72, 0.71, 0.1, 0.01, 0.28, 0.58, 0.04, 0.01, 0.26, 0.62, 0.11, 0.0, 0.45, 0.42, 0.01, 0.0, 0.46, 0.65, 0.12, 0.3, 0.0, 0.44, 0.32, 0.02, 0.55, 0.82, 0.44, 0.39, 0.66, 0.42, 0.01, 0.11, 0.62, 0.37, 0.01, 0.26, 0.67, 0.37, 0.0, 0.39, 0.73, 0.45, 0.01, 0.54, 0.68, 0.29, 0.0, 0.05, 0.37, 0.13, 0.41, 0.44, 0.08, 0.28, 0.05, 0.26, 0.76, 0.24, 0.54, 0.19, 0.41, 0.71, 0.81, 0.22, 0.37, 0.51, 0.45, 0.4, 0.58, 0.53, 0.72, 0.54, 0.49, 0.49, 0.53, 0.41, 0.59, 0.46, 0.54, 0.66, 0.51, 0.75, 0.63, 0.67, 0.56, 0.54, 0.52, 0.49, 0.51, 0.53, 0.58, 0.65, 0.51, 0.52, 0.56, 0.46, 0.66, 0.49, 0.52, 0.51, 0.39, 0.6, 0.46, 0.57, 0.39, 0.54, 0.57, 0.68, 0.54, 0.52, 0.6, 0.48, 0.33, 0.74, 0.84, 0.62, 0.36, 0.58, 0.57, 0.49, 0.37, 0.57, 0.54, 0.66, 0.63, 0.67, 0.39, 0.4, 0.5, 0.72, 0.61, 0.54, 0.49, 0.56, 0.75, 0.45, 0.6, 0.72, 0.47, 0.97, 0.95, 0.33, 0.81, 0.76, 0.79, 0.79, 0.98, 0.92, 0.76, 0.88, 0.68, 0.88, 0.81, 0.9, 0.85, 0.93, 0.99] | RING finger | Component of a SCF(SKP2)-like complex containing CUL1, SKP1, TRIM21 and SKP2. | SCF | null | IRF8, CALR, CUL1, FBXW11, HSPA5, IKBKB, IRF3, SKP1 , VCP,SKP2, DCP2 ,ULK1, BECN1,GABARAP, GABARAPL1, GABARAPL2 , MAP1LC3C,SQSTM1,IRF3 , NMI, IFI35 , CUL1, TRIM21 | USP4, IKBKB, TRIM21, CDKN1B, IRF3, IRF8, MNI | mono, 63 | null | UBE2D2, UBE2D1, UBE2E1, UBE2E2 | Homotrimer | null | 90.718042 | 0.406716 | 88.015919 | 0.456801 | 2,388 |
P19474 | P37198 | 34257278 | UbiBrowser | TRIM21 | MASAARLTMMWEEVTCPICLDPFVEPVSIECGHSFCQECISQVGKGGGSVCPVCRQRFLLKNLRPNRQLANMVNNLKEISQEAREGTQGERCAVHGERLHLFCEKDGKALCWVCAQSRKHRDHAMVPLEEAAQEYQEKLQVALGELRRKQELAEKLEVEIAIKRADWKKTVETQKSRIHAEFVQQKNFLVEEEQRQLQELEKDEREQLRILGEKEAKLAQQSQALQELISELDRRCHSSALELLQEVIIVLERSESWNLKDLDITSPELRSVCHVPGLKKMLRTCAVHITLDPDTANPWLILSEDRRQVRLGDTQQSIPGNEERFDSYPMVLGAQHFHSGKHYWEVDVTGKEAWDLGVCRDSVRRKGHFLLSSKSGFWTIWLWNKQKYEAGTYPQTPLHLQVPPCQVGIFLDYEAGMVSFYNITDHGSLIYSFSECAFTGPLRPFFSPGFNDGGKNTAPLTLCPLNIGSQGSTDY | Homo sapiens | Cytoplasm, Cytoplasmic vesicle, autophagosome, Nucleus, Cytoplasm, P-body, Cytoplasm, Stress granule | Low tissue specificity | {'Ciliated cells': '3.8', 'Basal respiratory cells': '6.8', 'Club cells': '5.8', 'Ionocytes': '3.7', 'Mucus glandular cells': '4.8', 'Serous glandular cells': '2.3', 'Gastric mucus-secreting cells': '8.8', 'Proximal enterocytes': '8.9', 'Paneth cells': '3.9', 'Distal enterocytes': '8.5', 'Intestinal goblet cells': '8.4', 'Exocrine glandular cells': '-0.716', 'Basal prostatic cells': '5.4', 'Prostatic glandular cells': '5.0', 'Breast glandular cells': '0.298', 'Breast myoepithelial cells': '0.351', 'Glandular and luminal cells': '5.9', 'Secretory cells': '8.4', 'Basal keratinocytes': '3.2', 'Suprabasal keratinocytes': '2.7', 'Basal squamous epithelial cells': '6.4', 'Squamous epithelial cells': '4.3', 'Alveolar cells type 1': '0.116', 'Alveolar cells type 2': '0.115', 'Salivary duct cells': '3.0', 'Ductal cells': '0.700', 'Hepatocytes': '0.503', 'Cholangiocytes': '11.4', 'Proximal tubular cells': '0.175', 'Distal tubular cells': '0.0', 'Collecting duct cells': '5.8', 'Mesothelial cells': '0.451', 'Sertoli cells': '0.479', 'Granulosa cells': '4.8', 'Enteroendocrine cells': '3.7', 'Pancreatic endocrine cells': '3.4', 'Leydig cells': '0.632', 'Excitatory neurons': '0.2', 'Inhibitory neurons': '0.1', 'Cone photoreceptor cells': '0.0', 'Rod photoreceptor cells': '0.0', 'Bipolar cells': '0.7', 'Horizontal cells': '0.6', 'Astrocytes': '0.0', 'Oligodendrocyte precursor cells': '0.9', 'Oligodendrocytes': '0.1', 'Microglial cells': '1.8', 'Muller glia cells': '2.4', 'Schwann cells': '0.099', 'Spermatogonia': '0.401', 'Spermatocytes': '-0.062', 'Early spermatids': '-0.578', 'Late spermatids': '-0.618', 'Oocytes': '1.5', 'Cytotrophoblasts': '6.6', 'Syncytiotrophoblasts': '9.8', 'Extravillous trophoblasts': '10.0', 'Endothelial cells': '7.8', 'Lymphatic endothelial cells': '6.9', 'Cardiomyocytes': '0.335', 'Skeletal myocytes': '-0.080', 'Smooth muscle cells': '6.3', 'Adipocytes': '8.3', 'Melanocytes': '0.101', 'Fibroblasts': '6.5', 'Peritubular cells': '0.579', 'Endometrial stromal cells': '4.5', 'Ovarian stromal cells': '6.7', 'Undifferentiated cells': '5.9', 'T-cells': '9.9', 'B-cells': '8.8', 'Plasma cells': '5.0', 'Nk-cells': '15.1', 'Granulocytes': '6.2', 'Monocytes': '7.8', 'Macrophages': '8.5', 'Hofbauer cells': '9.9', 'Kupffer cells': '10.3', 'Dendritic cells': '8.0', 'Langerhans cells': '0.466', 'Erythroid cells': '-0.084', 'Adipocytes (Subcutaneous)': '-0.368', 'Adipocytes (Visceral)': '-0.167', 'Breast glandular cells (progenitors)': '0.190', 'Adipocytes (Breast)': '-0.382', 'Colon enterocytes': '0.004', 'Colon enteroendocrine cells': '0.196', 'Enteric glia cells': '-0.129', 'Mitotic cells (Colon)': '0.005', 'Mitotic cells (Heart)': '0.486', 'Podocytes': '-0.114', 'Ascending Loop of Henle cells': '0.371', 'Intercalated cells': '-0.097', 'Cholangiocyte': '0.375', 'NK-cells (Liver)': '-0.278', 'Respiratory ciliated cells': '-0.022', 'Mitotic cells (Lung)': '0.157', 'NK-cells (Lung)': '0.110', 'B-cells (Lung)': '-0.155', 'Alpha cells': '0.333', 'Beta cells': '0.161', 'Prostate glandular cells': '-0.162', 'Prostate basal glandular cells': '0.286', 'Urothelial cells': '0.283', 'Keratinocyte (other)': '0.121', 'Keratinocyte (granular)': '-0.008', 'Hair cortex cells': '-0.113', 'Inner root sheath cells': '-0.069', 'Outer root sheath cells': '0.125', 'Sebaceous gland cells': '0.110', 'Eccrine sweat gland cells': '0.070', 'Adipocytes (Skin)': '0.019', 'Mitotic cells (Skin)': '0.236', 'Parietal cells': '-0.609', 'Chief cells': '-0.599', 'Gastric mucous cells': '-0.193', 'Gastric enteroendocrine cells': '-0.441', 'Mitotic cells (Stomach)': '0.261', 'Parafollicular cells': '-0.028', 'Thyroid glandular cells': '0.094', 'Mitotic cells (Thyroid)': '0.242', 'Adrenal cortex cells': '0.619', 'Adrenal medulla cells': '0.063', 'Mitotic cells (Adrenal gland)': '0.483', 'Minor salivary glandular cells': '0.582', 'Minor salivary gland ductal cells': '0.072', 'Minor salivary gland basal cells': '0.229', 'Mitotic cells (Minor salivary gland)': '0.376', 'Adipocytes (Minor salivary gland)': '0.211', 'Somatotropes': '-0.121', 'Lactotropes': '-0.287', 'Gonadotropes': '0.004', 'Corticotropes': '-0.352', 'Thyrotropes': '-0.054', 'Undifferentiated cells (Pituitary gland)': '0.486', 'Mitotic cells (Spleen)': '-0.016', 'Platelets': '0.115', 'Erythrocytes': '0.098', 'Hematopoietic stem cells': '0.042', 'B-cells (Spleen)': '0.028', 'NK-cells (Spleen)': '0.157', 'Amygdala excitatory': '0.1', 'Cerebellar inhibitory': '0.2', 'Cge interneuron': '0.3', 'Deep-layer corticothalamic and 6b': '0.3', 'Deep-layer intratelencephalic': '0.1', 'Deep-layer near-projecting': '0.1', 'Eccentric medium spiny neuron': '0.4', 'Hippocampal ca1-3': '0.5', 'Hippocampal ca4': '0.1', 'Hippocampal dentate gyrus': '0.3', 'Lamp5-lhx6 and chandelier': '0.3', 'Lower rhombic lip': '0.2', 'Mammillary body': '0.4', 'Medium spiny neuron': '0.6', 'Mge interneuron': '0.1', 'Midbrain-derived inhibitory': '0.6', 'Miscellaneous': '0.6', 'Splatter': '0.5', 'Thalamic excitatory': '1.3', 'Upper rhombic lip': '0.1', 'Upper-layer intratelencephalic': '0.1', 'Astrocyte': '1.5', 'Bergmann glia': '1.5', 'Central nervous system macrophage': '6.0', 'Choroid plexus epithelial cell': '2.9', 'Committed oligodendrocyte precursor': '1.0', 'Ependymal cell': '1.3', 'Oligodendrocyte': '0.1', 'Oligodendrocyte precursor cell': '2.3', 'Endothelial cell': '6.4', 'Pericyte': '5.3', 'Vascular associated smooth muscle cell': '3.1', 'Fibroblast': '5.3', 'Leukocyte': '7.4', 'Basophil': '107.0', 'Eosinophil': '312.5', 'Neutrophil': '496.9', 'Classical monocyte': '25.8', 'Non-classical monocyte': '66.1', 'Intermediate monocyte': '117.0', 'T-reg': '72.1', 'GdT-cell': '89.5', 'MAIT T-cell': '61.2', 'Memory CD4 T-cell': '76.8', 'Naive CD4 T-cell': '47.0', 'Memory CD8 T-cell': '81.1', 'Naive CD8 T-cell': '43.5', 'Memory B-cell': '50.4', 'Naive B-cell': '38.5', 'Plasmacytoid DC': '47.5', 'Myeloid DC': '92.2', 'NK-cell': '88.9', 'Total PBMC': '83.8', 'Vd2 gdTCR': '67.8', 'Memory CD4 T-cell Th1\\/Th17': '48.0', 'Memory CD4 T-cell Th17': '54.6', 'Memory CD4 T-cell Th2': '54.8', 'Non-Vd2 gdTCR': '73.7', 'Memory CD4 T-cell Th1': '58.8', 'Memory CD4 T-cell TFH': '61.9', 'Terminal effector memory CD4 T-cell': '72.8', 'Central memory CD8 T-cell': '59.9', 'Effector memory CD8 T-cell': '90.7', 'Terminal effector memory CD8 T-cell': '75.8', 'Non-switched memory B-cell': '52.6', 'Plasmablast': '62.3', 'Switched memory B-cell': '55.8', 'Exhausted memory B-cell': '52.1', 'Progenitor cell': '44.7', 'Memory T-reg': '82.4', 'Naive CD4 T-cell activated': '133.9', 'Naive CD8 T-cell activated': '163.4', 'Naive T-reg': '54.7'} | 2IWG, 5JPX, 5OLM, 6FGA, 6S53, 7BBD, 8A58 | {'Adipose Tissue': 21.42795099667774, 'Adrenal Gland': 16.707763565891472, 'Bladder': 21.861904761904764, 'Blood': 61.11958557588805, 'Blood Vessel': 22.62928389513109, 'Brain': 4.305000416351249, 'Breast': 20.001740740740743, 'Cervix Uteri': 26.420526315789473, 'Colon': 23.40817458279846, 'Esophagus': 21.74157577854671, 'Fallopian Tube': 25.39, 'Heart': 6.66628106852497, 'Kidney': 13.61479775280899, 'Liver': 10.388, 'Lung': 32.00464878892734, 'Muscle': 3.944284806973848, 'Nerve': 25.39305008077545, 'Ovary': 30.51811111111111, 'Pancreas': 6.808080182926829, 'Pituitary': 12.995699646643107, 'Prostate': 21.00597551020408, 'Salivary Gland': 16.434148148148147, 'Skin': 17.851811498065228, 'Small Intestine': 28.907085561497325, 'Spleen': 50.16024896265561, 'Stomach': 19.072721448467966, 'Testis': 6.377013850415512, 'Thyroid': 21.553307810107196, 'Uterus': 29.83549295774648, 'Vagina': 21.551141025641027} | NUP62 | MSGFNFGGTGAPTGGFTFGTAKTATTTPATGFSFSTSGTGGFNFGAPFQPATSTPSTGLFSLATQTPATQTTGFTFGTATLASGGTGFSLGIGASKLNLSNTAATPAMANPSGFGLGSSNLTNAISSTVTSSQGTAPTGFVFGPSTTSVAPATTSGGFSFTGGSTAQPSGFNIGSAGNSAQPTAPATLPFTPATPAATTAGATQPAAPTPTATITSTGPSLFASIATAPTSSATTGLSLCTPVTTAGAPTAGTQGFSLKAPGAASGTSTTTSTAATATATTTSSSSTTGFALNLKPLAPAGIPSNTAAAVTAPPGPGAAAGAAASSAMTYAQLESLINKWSLELEDQERHFLQQATQVNAWDRTLIENGEKITSLHREVEKVKLDQKRLDQELDFILSQQKELEDLLSPLEELVKEQSGTIYLQHADEEREKTYKLAENIDAQLKRMAQDLKDIIEHLNTSGAPADTSDPLQQICKILNAHMDSLQWIDQNSALLQRKVEEVTKVCEGRRKEQERSFRITFD | Homo sapiens | Nucleus, nuclear pore complex, Cytoplasm, cytoskeleton, spindle pole, Nucleus envelope, Cytoplasm, cytoskeleton, microtubule organizing center, centrosome | Low tissue specificity | {'Ciliated cells': '15.8', 'Basal respiratory cells': '15.2', 'Club cells': '20.1', 'Ionocytes': '12.5', 'Mucus glandular cells': '19.0', 'Serous glandular cells': '11.9', 'Gastric mucus-secreting cells': '19.5', 'Proximal enterocytes': '18.9', 'Paneth cells': '24.3', 'Distal enterocytes': '21.5', 'Intestinal goblet cells': '22.2', 'Exocrine glandular cells': '-0.772', 'Basal prostatic cells': '19.0', 'Prostatic glandular cells': '19.8', 'Breast glandular cells': '0.526', 'Breast myoepithelial cells': '0.468', 'Glandular and luminal cells': '24.8', 'Secretory cells': '30.0', 'Basal keratinocytes': '32.3', 'Suprabasal keratinocytes': '27.8', 'Basal squamous epithelial cells': '21.5', 'Squamous epithelial cells': '18.9', 'Alveolar cells type 1': '-0.122', 'Alveolar cells type 2': '0.047', 'Salivary duct cells': '17.4', 'Ductal cells': '0.664', 'Hepatocytes': '0.234', 'Cholangiocytes': '21.0', 'Proximal tubular cells': '0.258', 'Distal tubular cells': '0.0', 'Collecting duct cells': '9.7', 'Mesothelial cells': '0.407', 'Sertoli cells': '-0.452', 'Granulosa cells': '20.8', 'Enteroendocrine cells': '19.9', 'Pancreatic endocrine cells': '17.0', 'Leydig cells': '-0.497', 'Excitatory neurons': '0.0', 'Inhibitory neurons': '0.0', 'Cone photoreceptor cells': '17.0', 'Rod photoreceptor cells': '13.9', 'Bipolar cells': '13.0', 'Horizontal cells': '18.3', 'Astrocytes': '0.0', 'Oligodendrocyte precursor cells': '0.0', 'Oligodendrocytes': '0.0', 'Microglial cells': '0.0', 'Muller glia cells': '19.0', 'Schwann cells': '-0.080', 'Spermatogonia': '-0.108', 'Spermatocytes': '0.250', 'Early spermatids': '0.660', 'Late spermatids': '0.636', 'Oocytes': '54.4', 'Cytotrophoblasts': '39.9', 'Syncytiotrophoblasts': '22.1', 'Extravillous trophoblasts': '46.2', 'Endothelial cells': '23.3', 'Lymphatic endothelial cells': '14.7', 'Cardiomyocytes': '0.606', 'Skeletal myocytes': '-0.214', 'Smooth muscle cells': '16.7', 'Adipocytes': '15.9', 'Melanocytes': '0.288', 'Fibroblasts': '18.1', 'Peritubular cells': '-0.350', 'Endometrial stromal cells': '23.0', 'Ovarian stromal cells': '20.3', 'Undifferentiated cells': '35.1', 'T-cells': '23.4', 'B-cells': '28.9', 'Plasma cells': '28.3', 'Nk-cells': '20.1', 'Granulocytes': '26.9', 'Monocytes': '18.2', 'Macrophages': '45.9', 'Hofbauer cells': '52.1', 'Kupffer cells': '38.8', 'Dendritic cells': '52.8', 'Langerhans cells': '0.422', 'Erythroid cells': '0.071', 'Adipocytes (Subcutaneous)': '-0.288', 'Adipocytes (Visceral)': '-0.273', 'Breast glandular cells (progenitors)': '0.489', 'Adipocytes (Breast)': '-0.447', 'Colon enterocytes': '-0.111', 'Colon enteroendocrine cells': '0.250', 'Enteric glia cells': '0.000', 'Mitotic cells (Colon)': '-0.126', 'Mitotic cells (Heart)': '0.536', 'Podocytes': '-0.152', 'Ascending Loop of Henle cells': '0.357', 'Intercalated cells': '-0.158', 'Cholangiocyte': '0.215', 'NK-cells (Liver)': '-0.259', 'Respiratory ciliated cells': '-0.043', 'Mitotic cells (Lung)': '0.274', 'NK-cells (Lung)': '-0.012', 'B-cells (Lung)': '-0.098', 'Alpha cells': '0.432', 'Beta cells': '0.264', 'Prostate glandular cells': '-0.009', 'Prostate basal glandular cells': '0.363', 'Urothelial cells': '0.399', 'Keratinocyte (other)': '0.365', 'Keratinocyte (granular)': '0.082', 'Hair cortex cells': '-0.054', 'Inner root sheath cells': '-0.017', 'Outer root sheath cells': '0.074', 'Sebaceous gland cells': '0.114', 'Eccrine sweat gland cells': '-0.158', 'Adipocytes (Skin)': '-0.130', 'Mitotic cells (Skin)': '0.348', 'Parietal cells': '-0.620', 'Chief cells': '-0.522', 'Gastric mucous cells': '-0.243', 'Gastric enteroendocrine cells': '-0.340', 'Mitotic cells (Stomach)': '0.242', 'Parafollicular cells': '0.051', 'Thyroid glandular cells': '0.264', 'Mitotic cells (Thyroid)': '0.151', 'Adrenal cortex cells': '0.433', 'Adrenal medulla cells': '-0.112', 'Mitotic cells (Adrenal gland)': '0.235', 'Minor salivary glandular cells': '0.550', 'Minor salivary gland ductal cells': '0.035', 'Minor salivary gland basal cells': '0.297', 'Mitotic cells (Minor salivary gland)': '0.426', 'Adipocytes (Minor salivary gland)': '0.119', 'Somatotropes': '0.236', 'Lactotropes': '0.261', 'Gonadotropes': '0.141', 'Corticotropes': '0.077', 'Thyrotropes': '0.209', 'Undifferentiated cells (Pituitary gland)': '0.095', 'Mitotic cells (Spleen)': '0.074', 'Platelets': '-0.085', 'Erythrocytes': '-0.106', 'Hematopoietic stem cells': '-0.216', 'B-cells (Spleen)': '0.353', 'NK-cells (Spleen)': '0.152', 'Amygdala excitatory': '0.0', 'Cerebellar inhibitory': '0.1', 'Cge interneuron': '0.1', 'Deep-layer corticothalamic and 6b': '0.0', 'Deep-layer intratelencephalic': '0.0', 'Deep-layer near-projecting': '0.0', 'Eccentric medium spiny neuron': '0.0', 'Hippocampal ca1-3': '0.0', 'Hippocampal ca4': '0.0', 'Hippocampal dentate gyrus': '0.1', 'Lamp5-lhx6 and chandelier': '0.0', 'Lower rhombic lip': '0.0', 'Mammillary body': '0.1', 'Medium spiny neuron': '0.0', 'Mge interneuron': '0.0', 'Midbrain-derived inhibitory': '0.0', 'Miscellaneous': '0.0', 'Splatter': '0.1', 'Thalamic excitatory': '0.0', 'Upper rhombic lip': '0.1', 'Upper-layer intratelencephalic': '0.2', 'Astrocyte': '0.1', 'Bergmann glia': '0.0', 'Central nervous system macrophage': '0.1', 'Choroid plexus epithelial cell': '0.0', 'Committed oligodendrocyte precursor': '0.0', 'Ependymal cell': '0.1', 'Oligodendrocyte': '0.1', 'Oligodendrocyte precursor cell': '0.1', 'Endothelial cell': '0.3', 'Pericyte': '0.1', 'Vascular associated smooth muscle cell': '0.0', 'Fibroblast': '0.2', 'Leukocyte': '0.0', 'Basophil': '31.7', 'Eosinophil': '7.2', 'Neutrophil': '20.8', 'Classical monocyte': '29.7', 'Non-classical monocyte': '20.6', 'Intermediate monocyte': '106.5', 'T-reg': '50.9', 'GdT-cell': '17.9', 'MAIT T-cell': '85.8', 'Memory CD4 T-cell': '17.9', 'Naive CD4 T-cell': '16.0', 'Memory CD8 T-cell': '20.0', 'Naive CD8 T-cell': '16.7', 'Memory B-cell': '15.5', 'Naive B-cell': '11.5', 'Plasmacytoid DC': '128.9', 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0.52, 0.8, 0.39, 0.59, 0.63, 0.12, 0.58, 0.52, 0.34, 0.2, 0.44, 0.61, 0.44, 0.54, 0.55, 0.57, 0.61, 0.44, 0.56, 0.46, 0.68, 0.54, 0.68, 0.63, 0.37, 0.5, 0.5, 0.54, 0.64, 0.59, 0.72, 0.51, 0.55, 0.41, 0.47, 0.59, 0.49, 0.63, 0.55, 0.51, 0.39, 0.37, 0.63, 0.44, 0.19, 0.44, 0.64, 0.37, 0.37, 0.5, 0.59, 0.71, 0.76, 0.77, 0.73, 0.85] | RING finger | Component of a SCF(SKP2)-like complex containing CUL1, SKP1, TRIM21 and SKP2. | SCF | null | IRF8, CALR, CUL1, FBXW11, HSPA5, IKBKB, IRF3, SKP1 , VCP,SKP2, DCP2 ,ULK1, BECN1,GABARAP, GABARAPL1, GABARAPL2 , MAP1LC3C,SQSTM1,IRF3 , NMI, IFI35 , CUL1, TRIM21 | USP4, IKBKB, TRIM21, CDKN1B, IRF3, IRF8, MNI | mono, 63 | null | UBE2D2, UBE2D1, UBE2E1, UBE2E2 | Homotrimer | null | 90.718042 | 0.406716 | 57.621475 | 0.799023 | 1,492 |
P19474 | P38936 | 33900537 | UbiBrowser | TRIM21 | MASAARLTMMWEEVTCPICLDPFVEPVSIECGHSFCQECISQVGKGGGSVCPVCRQRFLLKNLRPNRQLANMVNNLKEISQEAREGTQGERCAVHGERLHLFCEKDGKALCWVCAQSRKHRDHAMVPLEEAAQEYQEKLQVALGELRRKQELAEKLEVEIAIKRADWKKTVETQKSRIHAEFVQQKNFLVEEEQRQLQELEKDEREQLRILGEKEAKLAQQSQALQELISELDRRCHSSALELLQEVIIVLERSESWNLKDLDITSPELRSVCHVPGLKKMLRTCAVHITLDPDTANPWLILSEDRRQVRLGDTQQSIPGNEERFDSYPMVLGAQHFHSGKHYWEVDVTGKEAWDLGVCRDSVRRKGHFLLSSKSGFWTIWLWNKQKYEAGTYPQTPLHLQVPPCQVGIFLDYEAGMVSFYNITDHGSLIYSFSECAFTGPLRPFFSPGFNDGGKNTAPLTLCPLNIGSQGSTDY | Homo sapiens | Cytoplasm, Cytoplasmic vesicle, autophagosome, Nucleus, Cytoplasm, P-body, Cytoplasm, Stress granule | Low tissue specificity | {'Ciliated cells': '3.8', 'Basal respiratory cells': '6.8', 'Club cells': '5.8', 'Ionocytes': '3.7', 'Mucus glandular cells': '4.8', 'Serous glandular cells': '2.3', 'Gastric mucus-secreting cells': '8.8', 'Proximal enterocytes': '8.9', 'Paneth cells': '3.9', 'Distal enterocytes': '8.5', 'Intestinal goblet cells': '8.4', 'Exocrine glandular cells': '-0.716', 'Basal prostatic cells': '5.4', 'Prostatic glandular cells': '5.0', 'Breast glandular cells': '0.298', 'Breast myoepithelial cells': '0.351', 'Glandular and luminal cells': '5.9', 'Secretory cells': '8.4', 'Basal keratinocytes': '3.2', 'Suprabasal keratinocytes': '2.7', 'Basal squamous epithelial cells': '6.4', 'Squamous epithelial cells': '4.3', 'Alveolar cells type 1': '0.116', 'Alveolar cells type 2': '0.115', 'Salivary duct cells': '3.0', 'Ductal cells': '0.700', 'Hepatocytes': '0.503', 'Cholangiocytes': '11.4', 'Proximal tubular cells': '0.175', 'Distal tubular cells': '0.0', 'Collecting duct cells': '5.8', 'Mesothelial cells': '0.451', 'Sertoli cells': '0.479', 'Granulosa cells': '4.8', 'Enteroendocrine cells': '3.7', 'Pancreatic endocrine cells': '3.4', 'Leydig cells': '0.632', 'Excitatory neurons': '0.2', 'Inhibitory neurons': '0.1', 'Cone photoreceptor cells': '0.0', 'Rod photoreceptor cells': '0.0', 'Bipolar cells': '0.7', 'Horizontal cells': '0.6', 'Astrocytes': '0.0', 'Oligodendrocyte precursor cells': '0.9', 'Oligodendrocytes': '0.1', 'Microglial cells': '1.8', 'Muller glia cells': '2.4', 'Schwann cells': '0.099', 'Spermatogonia': '0.401', 'Spermatocytes': '-0.062', 'Early spermatids': '-0.578', 'Late spermatids': '-0.618', 'Oocytes': '1.5', 'Cytotrophoblasts': '6.6', 'Syncytiotrophoblasts': '9.8', 'Extravillous trophoblasts': '10.0', 'Endothelial cells': '7.8', 'Lymphatic endothelial cells': '6.9', 'Cardiomyocytes': '0.335', 'Skeletal myocytes': '-0.080', 'Smooth muscle cells': '6.3', 'Adipocytes': '8.3', 'Melanocytes': '0.101', 'Fibroblasts': '6.5', 'Peritubular cells': '0.579', 'Endometrial stromal cells': '4.5', 'Ovarian stromal cells': '6.7', 'Undifferentiated cells': '5.9', 'T-cells': '9.9', 'B-cells': '8.8', 'Plasma cells': '5.0', 'Nk-cells': '15.1', 'Granulocytes': '6.2', 'Monocytes': '7.8', 'Macrophages': '8.5', 'Hofbauer cells': '9.9', 'Kupffer cells': '10.3', 'Dendritic cells': '8.0', 'Langerhans cells': '0.466', 'Erythroid cells': '-0.084', 'Adipocytes (Subcutaneous)': '-0.368', 'Adipocytes (Visceral)': '-0.167', 'Breast glandular cells (progenitors)': '0.190', 'Adipocytes (Breast)': '-0.382', 'Colon enterocytes': '0.004', 'Colon enteroendocrine cells': '0.196', 'Enteric glia cells': '-0.129', 'Mitotic cells (Colon)': '0.005', 'Mitotic cells (Heart)': '0.486', 'Podocytes': '-0.114', 'Ascending Loop of Henle cells': '0.371', 'Intercalated cells': '-0.097', 'Cholangiocyte': '0.375', 'NK-cells (Liver)': '-0.278', 'Respiratory ciliated cells': '-0.022', 'Mitotic cells (Lung)': '0.157', 'NK-cells (Lung)': '0.110', 'B-cells (Lung)': '-0.155', 'Alpha cells': '0.333', 'Beta cells': '0.161', 'Prostate glandular cells': '-0.162', 'Prostate basal glandular cells': '0.286', 'Urothelial cells': '0.283', 'Keratinocyte (other)': '0.121', 'Keratinocyte (granular)': '-0.008', 'Hair cortex cells': '-0.113', 'Inner root sheath cells': '-0.069', 'Outer root sheath cells': '0.125', 'Sebaceous gland cells': '0.110', 'Eccrine sweat gland cells': '0.070', 'Adipocytes (Skin)': '0.019', 'Mitotic cells (Skin)': '0.236', 'Parietal cells': '-0.609', 'Chief cells': '-0.599', 'Gastric mucous cells': '-0.193', 'Gastric enteroendocrine cells': '-0.441', 'Mitotic cells (Stomach)': '0.261', 'Parafollicular cells': '-0.028', 'Thyroid glandular cells': '0.094', 'Mitotic cells (Thyroid)': '0.242', 'Adrenal cortex cells': '0.619', 'Adrenal medulla cells': '0.063', 'Mitotic cells (Adrenal gland)': '0.483', 'Minor salivary glandular cells': '0.582', 'Minor salivary gland ductal cells': '0.072', 'Minor salivary gland basal cells': '0.229', 'Mitotic cells (Minor salivary gland)': '0.376', 'Adipocytes (Minor salivary gland)': '0.211', 'Somatotropes': '-0.121', 'Lactotropes': '-0.287', 'Gonadotropes': '0.004', 'Corticotropes': '-0.352', 'Thyrotropes': '-0.054', 'Undifferentiated cells (Pituitary gland)': '0.486', 'Mitotic cells (Spleen)': '-0.016', 'Platelets': '0.115', 'Erythrocytes': '0.098', 'Hematopoietic stem cells': '0.042', 'B-cells (Spleen)': '0.028', 'NK-cells (Spleen)': '0.157', 'Amygdala excitatory': '0.1', 'Cerebellar inhibitory': '0.2', 'Cge interneuron': '0.3', 'Deep-layer corticothalamic and 6b': '0.3', 'Deep-layer intratelencephalic': '0.1', 'Deep-layer near-projecting': '0.1', 'Eccentric medium spiny neuron': '0.4', 'Hippocampal ca1-3': '0.5', 'Hippocampal ca4': '0.1', 'Hippocampal dentate gyrus': '0.3', 'Lamp5-lhx6 and chandelier': '0.3', 'Lower rhombic lip': '0.2', 'Mammillary body': '0.4', 'Medium spiny neuron': '0.6', 'Mge interneuron': '0.1', 'Midbrain-derived inhibitory': '0.6', 'Miscellaneous': '0.6', 'Splatter': '0.5', 'Thalamic excitatory': '1.3', 'Upper rhombic lip': '0.1', 'Upper-layer intratelencephalic': '0.1', 'Astrocyte': '1.5', 'Bergmann glia': '1.5', 'Central nervous system macrophage': '6.0', 'Choroid plexus epithelial cell': '2.9', 'Committed oligodendrocyte precursor': '1.0', 'Ependymal cell': '1.3', 'Oligodendrocyte': '0.1', 'Oligodendrocyte precursor cell': '2.3', 'Endothelial cell': '6.4', 'Pericyte': '5.3', 'Vascular associated smooth muscle cell': '3.1', 'Fibroblast': '5.3', 'Leukocyte': '7.4', 'Basophil': '107.0', 'Eosinophil': '312.5', 'Neutrophil': '496.9', 'Classical monocyte': '25.8', 'Non-classical monocyte': '66.1', 'Intermediate monocyte': '117.0', 'T-reg': '72.1', 'GdT-cell': '89.5', 'MAIT T-cell': '61.2', 'Memory CD4 T-cell': '76.8', 'Naive CD4 T-cell': '47.0', 'Memory CD8 T-cell': '81.1', 'Naive CD8 T-cell': '43.5', 'Memory B-cell': '50.4', 'Naive B-cell': '38.5', 'Plasmacytoid DC': '47.5', 'Myeloid DC': '92.2', 'NK-cell': '88.9', 'Total PBMC': '83.8', 'Vd2 gdTCR': '67.8', 'Memory CD4 T-cell Th1\\/Th17': '48.0', 'Memory CD4 T-cell Th17': '54.6', 'Memory CD4 T-cell Th2': '54.8', 'Non-Vd2 gdTCR': '73.7', 'Memory CD4 T-cell Th1': '58.8', 'Memory CD4 T-cell TFH': '61.9', 'Terminal effector memory CD4 T-cell': '72.8', 'Central memory CD8 T-cell': '59.9', 'Effector memory CD8 T-cell': '90.7', 'Terminal effector memory CD8 T-cell': '75.8', 'Non-switched memory B-cell': '52.6', 'Plasmablast': '62.3', 'Switched memory B-cell': '55.8', 'Exhausted memory B-cell': '52.1', 'Progenitor cell': '44.7', 'Memory T-reg': '82.4', 'Naive CD4 T-cell activated': '133.9', 'Naive CD8 T-cell activated': '163.4', 'Naive T-reg': '54.7'} | 2IWG, 5JPX, 5OLM, 6FGA, 6S53, 7BBD, 8A58 | {'Adipose Tissue': 21.42795099667774, 'Adrenal Gland': 16.707763565891472, 'Bladder': 21.861904761904764, 'Blood': 61.11958557588805, 'Blood Vessel': 22.62928389513109, 'Brain': 4.305000416351249, 'Breast': 20.001740740740743, 'Cervix Uteri': 26.420526315789473, 'Colon': 23.40817458279846, 'Esophagus': 21.74157577854671, 'Fallopian Tube': 25.39, 'Heart': 6.66628106852497, 'Kidney': 13.61479775280899, 'Liver': 10.388, 'Lung': 32.00464878892734, 'Muscle': 3.944284806973848, 'Nerve': 25.39305008077545, 'Ovary': 30.51811111111111, 'Pancreas': 6.808080182926829, 'Pituitary': 12.995699646643107, 'Prostate': 21.00597551020408, 'Salivary Gland': 16.434148148148147, 'Skin': 17.851811498065228, 'Small Intestine': 28.907085561497325, 'Spleen': 50.16024896265561, 'Stomach': 19.072721448467966, 'Testis': 6.377013850415512, 'Thyroid': 21.553307810107196, 'Uterus': 29.83549295774648, 'Vagina': 21.551141025641027} | CDKN1A | MSEPAGDVRQNPCGSKACRRLFGPVDSEQLSRDCDALMAGCIQEARERWNFDFVTETPLEGDFAWERVRGLGLPKLYLPTGPRRGRDELGGGRRPGTSPALLQGTAEEDHVDLSLSCTLVPRSGEQAEGSPGGPGDSQGRKRRQTSMTDFYHSKRRLIFSKRKP | Homo sapiens | Cytoplasm, Nucleus | Low tissue specificity | {'Ciliated cells': '219.2', 'Basal respiratory cells': '269.5', 'Club cells': '189.1', 'Ionocytes': '279.8', 'Mucus glandular cells': '202.6', 'Serous glandular cells': '151.8', 'Gastric mucus-secreting cells': '136.2', 'Proximal enterocytes': '345.5', 'Paneth cells': '170.9', 'Distal enterocytes': '374.3', 'Intestinal goblet cells': '199.6', 'Exocrine glandular cells': '-0.503', 'Basal prostatic cells': '263.3', 'Prostatic glandular cells': '36.9', 'Breast glandular cells': '-0.093', 'Breast myoepithelial cells': '0.013', 'Glandular and luminal cells': '205.8', 'Secretory cells': '211.3', 'Basal keratinocytes': '338.3', 'Suprabasal keratinocytes': '625.4', 'Basal squamous epithelial cells': '564.7', 'Squamous epithelial cells': '599.4', 'Alveolar cells type 1': '-0.006', 'Alveolar cells type 2': '-0.268', 'Salivary duct cells': '211.4', 'Ductal cells': '0.254', 'Hepatocytes': '-0.189', 'Cholangiocytes': '24.8', 'Proximal tubular cells': '0.179', 'Distal tubular cells': '43.0', 'Collecting duct cells': '77.8', 'Mesothelial cells': '-0.166', 'Sertoli cells': '0.547', 'Granulosa cells': '96.6', 'Enteroendocrine cells': '226.3', 'Pancreatic endocrine cells': '156.2', 'Leydig cells': '0.537', 'Excitatory neurons': '0.4', 'Inhibitory neurons': '0.4', 'Cone photoreceptor cells': '0.0', 'Rod photoreceptor cells': '0.8', 'Bipolar cells': '1.2', 'Horizontal cells': '1.3', 'Astrocytes': '0.9', 'Oligodendrocyte precursor cells': '0.0', 'Oligodendrocytes': '0.4', 'Microglial cells': '5.4', 'Muller glia cells': '67.7', 'Schwann cells': '-0.047', 'Spermatogonia': '0.312', 'Spermatocytes': '-0.173', 'Early spermatids': '-0.577', 'Late spermatids': '-0.573', 'Oocytes': '17.6', 'Cytotrophoblasts': '40.0', 'Syncytiotrophoblasts': '172.4', 'Extravillous trophoblasts': '57.7', 'Endothelial cells': '417.4', 'Lymphatic endothelial cells': '198.2', 'Cardiomyocytes': '0.152', 'Skeletal myocytes': '-0.199', 'Smooth muscle cells': '464.8', 'Adipocytes': '577.5', 'Melanocytes': '0.167', 'Fibroblasts': '258.4', 'Peritubular cells': '0.389', 'Endometrial stromal cells': '54.7', 'Ovarian stromal cells': '204.0', 'Undifferentiated cells': '43.2', 'T-cells': '98.5', 'B-cells': '134.5', 'Plasma cells': '326.2', 'Nk-cells': '26.2', 'Granulocytes': '246.5', 'Monocytes': '506.5', 'Macrophages': '288.1', 'Hofbauer cells': '139.3', 'Kupffer cells': '74.3', 'Dendritic cells': '95.0', 'Langerhans cells': '-0.032', 'Erythroid cells': '0.037', 'Adipocytes (Subcutaneous)': '-0.360', 'Adipocytes (Visceral)': '0.069', 'Breast glandular cells (progenitors)': '-0.168', 'Adipocytes (Breast)': '-0.071', 'Colon enterocytes': '-0.005', 'Colon enteroendocrine cells': '-0.041', 'Enteric glia cells': '-0.179', 'Mitotic cells (Colon)': '0.208', 'Mitotic cells (Heart)': '0.293', 'Podocytes': '0.152', 'Ascending Loop of Henle cells': '-0.065', 'Intercalated cells': '-0.145', 'Cholangiocyte': '0.343', 'NK-cells (Liver)': '-0.217', 'Respiratory ciliated cells': '-0.033', 'Mitotic cells (Lung)': '-0.190', 'NK-cells (Lung)': '0.157', 'B-cells (Lung)': '0.184', 'Alpha cells': '0.226', 'Beta cells': '0.160', 'Prostate glandular cells': '-0.244', 'Prostate basal glandular cells': '-0.132', 'Urothelial cells': '0.171', 'Keratinocyte (other)': '0.183', 'Keratinocyte (granular)': '-0.193', 'Hair cortex cells': '0.051', 'Inner root sheath cells': '0.111', 'Outer root sheath cells': '0.189', 'Sebaceous gland cells': '-0.160', 'Eccrine sweat gland cells': '-0.080', 'Adipocytes (Skin)': '-0.298', 'Mitotic cells (Skin)': '0.119', 'Parietal cells': '-0.445', 'Chief cells': '-0.447', 'Gastric mucous cells': '-0.250', 'Gastric enteroendocrine cells': '-0.355', 'Mitotic cells (Stomach)': '-0.063', 'Parafollicular cells': '-0.038', 'Thyroid glandular cells': '-0.105', 'Mitotic cells (Thyroid)': '0.052', 'Adrenal cortex cells': '0.188', 'Adrenal medulla cells': '0.047', 'Mitotic cells (Adrenal gland)': '-0.087', 'Minor salivary glandular cells': '0.239', 'Minor salivary gland ductal cells': '-0.263', 'Minor salivary gland basal cells': '0.564', 'Mitotic cells (Minor salivary gland)': '0.575', 'Adipocytes (Minor salivary gland)': '0.299', 'Somatotropes': '-0.188', 'Lactotropes': '-0.361', 'Gonadotropes': '-0.142', 'Corticotropes': '0.095', 'Thyrotropes': '-0.132', 'Undifferentiated cells (Pituitary gland)': '-0.032', 'Mitotic cells (Spleen)': '-0.164', 'Platelets': '-0.169', 'Erythrocytes': '-0.115', 'Hematopoietic stem cells': '-0.168', 'B-cells (Spleen)': '0.081', 'NK-cells (Spleen)': '-0.017', 'Amygdala excitatory': '0.8', 'Cerebellar inhibitory': '0.3', 'Cge interneuron': '0.4', 'Deep-layer corticothalamic and 6b': '1.0', 'Deep-layer intratelencephalic': '1.2', 'Deep-layer near-projecting': '0.2', 'Eccentric medium spiny neuron': '0.9', 'Hippocampal ca1-3': '0.4', 'Hippocampal ca4': '0.1', 'Hippocampal dentate gyrus': '0.3', 'Lamp5-lhx6 and chandelier': '0.1', 'Lower rhombic lip': '0.1', 'Mammillary body': '0.1', 'Medium spiny neuron': '0.8', 'Mge interneuron': '0.9', 'Midbrain-derived inhibitory': '0.1', 'Miscellaneous': '0.6', 'Splatter': '1.3', 'Thalamic excitatory': '0.3', 'Upper rhombic lip': '0.2', 'Upper-layer intratelencephalic': '1.0', 'Astrocyte': '3.7', 'Bergmann glia': '0.8', 'Central nervous system macrophage': '45.6', 'Choroid plexus epithelial cell': '57.6', 'Committed oligodendrocyte precursor': '1.5', 'Ependymal cell': '24.7', 'Oligodendrocyte': '0.2', 'Oligodendrocyte precursor cell': '0.7', 'Endothelial cell': '56.7', 'Pericyte': '8.8', 'Vascular associated smooth muscle cell': '46.9', 'Fibroblast': '10.3', 'Leukocyte': '8.0', 'Basophil': '2.2', 'Eosinophil': '0.5', 'Neutrophil': '7.6', 'Classical monocyte': '484.7', 'Non-classical monocyte': '172.5', 'Intermediate monocyte': '412.1', 'T-reg': '5.5', 'GdT-cell': '0.5', 'MAIT T-cell': '17.0', 'Memory CD4 T-cell': '1.1', 'Naive CD4 T-cell': '3.1', 'Memory CD8 T-cell': '0.6', 'Naive CD8 T-cell': '3.5', 'Memory B-cell': '20.8', 'Naive B-cell': '99.9', 'Plasmacytoid DC': '81.5', 'Myeloid DC': '344.0', 'NK-cell': '4.9', 'Total PBMC': '259.7', 'Vd2 gdTCR': '12.6', 'Memory CD4 T-cell Th1\\/Th17': '56.7', 'Memory CD4 T-cell Th17': '32.8', 'Memory CD4 T-cell Th2': '24.5', 'Non-Vd2 gdTCR': '14.0', 'Memory CD4 T-cell Th1': '42.0', 'Memory CD4 T-cell TFH': '12.6', 'Terminal effector memory CD4 T-cell': '5.2', 'Central memory CD8 T-cell': '4.1', 'Effector memory CD8 T-cell': '6.5', 'Terminal effector memory CD8 T-cell': '10.8', 'Non-switched memory B-cell': '126.9', 'Plasmablast': '79.6', 'Switched memory B-cell': '92.1', 'Exhausted memory B-cell': '109.4', 'Progenitor cell': '19.9', 'Memory T-reg': '14.0', 'Naive CD4 T-cell activated': '83.2', 'Naive CD8 T-cell activated': '40.7', 'Naive T-reg': '3.2'} | 1AXC, 2ZVV, 2ZVW, 4RJF, 5E0U, 6CBI, 6CEJ, 6CIV, 6CIX, 6P8H, 7KQ0, 7KQ1, 8GJF | {'Adipose Tissue': 298.2111129568106, 'Adrenal Gland': 93.4060465116279, 'Bladder': 197.83761904761903, 'Blood': 78.93353928955867, 'Blood Vessel': 448.1661423220974, 'Brain': 26.16142089326268, 'Breast': 190.7731372549019, 'Cervix Uteri': 154.54263157894738, 'Colon': 136.42021822849807, 'Esophagus': 163.55013148788927, 'Fallopian Tube': 361.2999999999999, 'Heart': 85.2329837398374, 'Kidney': 85.09125842696629, 'Liver': 87.66353539823008, 'Lung': 274.2942560553633, 'Muscle': 150.03065255292654, 'Nerve': 203.34387722132473, 'Ovary': 296.445, 'Pancreas': 57.98804878048781, 'Pituitary': 149.13120141342756, 'Prostate': 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42.1, 41.96, 49.04, 54.49, 40.1, 41.62, 44.88, 39.83, 48.69, 39.11, 40.6, 45.92, 33.81, 36.52, 35.52, 41.52, 42.69, 51.4, 44.01, 54.81, 55.66, 49.71, 55.25, 47.45, 51.51, 47.75, 43.71, 46.45, 60.31, 63.94, 55.05, 51.38, 42.11, 43.98, 44.68, 41.84, 41.46, 49.37, 49.4, 49.36, 46.84, 45.02, 57.78, 46.67, 46.47, 51.42, 62.97, 62.03, 45.33, 62.65, 68.04, 72.15, 74.86, 77.44, 74.32, 74.89, 75.34, 71.44, 62.9, 62.6, 60.64, 60.73, 60.71, 62.32, 62.22, 63.79, 58.88, 59.41, 57.55, 57.62, 60.05, 50.89, 58.14, 66.56] | [0.97, 0.93, 0.96, 0.92, 0.91, 0.77, 0.69, 0.78, 0.8, 0.86, 0.4, 0.89, 0.43, 0.95, 0.47, 0.87, 0.77, 0.39, 0.71, 0.71, 0.78, 0.98, 0.42, 0.89, 0.71, 0.59, 0.67, 0.71, 0.39, 0.53, 0.43, 0.54, 0.46, 0.41, 0.53, 0.59, 0.68, 0.54, 0.51, 0.47, 0.59, 0.41, 0.45, 0.63, 0.21, 0.39, 0.69, 0.77, 0.49, 0.09, 0.18, 0.17, 0.45, 0.72, 0.6, 0.57, 0.46, 0.53, 0.33, 0.98, 0.68, 0.95, 0.42, 0.94, 0.45, 0.87, 0.87, 0.55, 0.89, 0.43, 0.94, 0.81, 0.38, 0.56, 0.79, 0.82, 0.73, 0.38, 0.68, 0.92, 0.66, 0.9, 0.78, 0.91, 0.72, 0.97, 0.93, 0.93, 1.0, 0.85, 1.0, 1.0, 1.0, 0.98, 0.94, 0.9, 0.94, 0.91, 0.95, 0.87, 0.97, 1.0, 0.99, 0.93, 0.99, 0.88, 1.0, 0.98, 0.83, 0.97, 0.65, 0.84, 0.61, 0.66, 0.82, 0.71, 0.8, 0.82, 0.84, 0.83, 0.86, 0.95, 0.94, 0.93, 1.0, 0.99, 1.0, 0.99, 1.0, 1.0, 1.0, 1.0, 0.99, 0.98, 0.94, 0.98, 0.95, 0.95, 0.94, 0.93, 0.93, 0.94, 0.92, 0.95, 0.89, 0.68, 0.87, 0.59, 0.83, 0.83, 0.82, 0.84, 0.79, 0.83, 0.87, 0.87, 0.7, 0.82, 0.76, 0.78, 0.93, 0.98, 0.98, 1.0] | RING finger | Component of a SCF(SKP2)-like complex containing CUL1, SKP1, TRIM21 and SKP2. | SCF | null | IRF8, CALR, CUL1, FBXW11, HSPA5, IKBKB, IRF3, SKP1 , VCP,SKP2, DCP2 ,ULK1, BECN1,GABARAP, GABARAPL1, GABARAPL2 , MAP1LC3C,SQSTM1,IRF3 , NMI, IFI35 , CUL1, TRIM21 | USP4, IKBKB, TRIM21, CDKN1B, IRF3, IRF8, MNI | mono, 63 | null | UBE2D2, UBE2D1, UBE2E1, UBE2E2 | Homotrimer | null | 90.718042 | 0.406716 | 68.75 | 0.766829 | 2,849 |
P19474 | P46527 | 10323868, RO52_HUMAN, E3Net | UbiNet, UbiBrowser, 31181401 | TRIM21 | MASAARLTMMWEEVTCPICLDPFVEPVSIECGHSFCQECISQVGKGGGSVCPVCRQRFLLKNLRPNRQLANMVNNLKEISQEAREGTQGERCAVHGERLHLFCEKDGKALCWVCAQSRKHRDHAMVPLEEAAQEYQEKLQVALGELRRKQELAEKLEVEIAIKRADWKKTVETQKSRIHAEFVQQKNFLVEEEQRQLQELEKDEREQLRILGEKEAKLAQQSQALQELISELDRRCHSSALELLQEVIIVLERSESWNLKDLDITSPELRSVCHVPGLKKMLRTCAVHITLDPDTANPWLILSEDRRQVRLGDTQQSIPGNEERFDSYPMVLGAQHFHSGKHYWEVDVTGKEAWDLGVCRDSVRRKGHFLLSSKSGFWTIWLWNKQKYEAGTYPQTPLHLQVPPCQVGIFLDYEAGMVSFYNITDHGSLIYSFSECAFTGPLRPFFSPGFNDGGKNTAPLTLCPLNIGSQGSTDY | Homo sapiens | Cytoplasm, Cytoplasmic vesicle, autophagosome, Nucleus, Cytoplasm, P-body, Cytoplasm, Stress granule | Low tissue specificity | {'Ciliated cells': '3.8', 'Basal respiratory cells': '6.8', 'Club cells': '5.8', 'Ionocytes': '3.7', 'Mucus glandular cells': '4.8', 'Serous glandular cells': '2.3', 'Gastric mucus-secreting cells': '8.8', 'Proximal enterocytes': '8.9', 'Paneth cells': '3.9', 'Distal enterocytes': '8.5', 'Intestinal goblet cells': '8.4', 'Exocrine glandular cells': '-0.716', 'Basal prostatic cells': '5.4', 'Prostatic glandular cells': '5.0', 'Breast glandular cells': '0.298', 'Breast myoepithelial cells': '0.351', 'Glandular and luminal cells': '5.9', 'Secretory cells': '8.4', 'Basal keratinocytes': '3.2', 'Suprabasal keratinocytes': '2.7', 'Basal squamous epithelial cells': '6.4', 'Squamous epithelial cells': '4.3', 'Alveolar cells type 1': '0.116', 'Alveolar cells type 2': '0.115', 'Salivary duct cells': '3.0', 'Ductal cells': '0.700', 'Hepatocytes': '0.503', 'Cholangiocytes': '11.4', 'Proximal tubular cells': '0.175', 'Distal tubular cells': '0.0', 'Collecting duct cells': '5.8', 'Mesothelial cells': '0.451', 'Sertoli cells': '0.479', 'Granulosa cells': '4.8', 'Enteroendocrine cells': '3.7', 'Pancreatic endocrine cells': '3.4', 'Leydig cells': '0.632', 'Excitatory neurons': '0.2', 'Inhibitory neurons': '0.1', 'Cone photoreceptor cells': '0.0', 'Rod photoreceptor cells': '0.0', 'Bipolar cells': '0.7', 'Horizontal cells': '0.6', 'Astrocytes': '0.0', 'Oligodendrocyte precursor cells': '0.9', 'Oligodendrocytes': '0.1', 'Microglial cells': '1.8', 'Muller glia cells': '2.4', 'Schwann cells': '0.099', 'Spermatogonia': '0.401', 'Spermatocytes': '-0.062', 'Early spermatids': '-0.578', 'Late spermatids': '-0.618', 'Oocytes': '1.5', 'Cytotrophoblasts': '6.6', 'Syncytiotrophoblasts': '9.8', 'Extravillous trophoblasts': '10.0', 'Endothelial cells': '7.8', 'Lymphatic endothelial cells': '6.9', 'Cardiomyocytes': '0.335', 'Skeletal myocytes': '-0.080', 'Smooth muscle cells': '6.3', 'Adipocytes': '8.3', 'Melanocytes': '0.101', 'Fibroblasts': '6.5', 'Peritubular cells': '0.579', 'Endometrial stromal cells': '4.5', 'Ovarian stromal cells': '6.7', 'Undifferentiated cells': '5.9', 'T-cells': '9.9', 'B-cells': '8.8', 'Plasma cells': '5.0', 'Nk-cells': '15.1', 'Granulocytes': '6.2', 'Monocytes': '7.8', 'Macrophages': '8.5', 'Hofbauer cells': '9.9', 'Kupffer cells': '10.3', 'Dendritic cells': '8.0', 'Langerhans cells': '0.466', 'Erythroid cells': '-0.084', 'Adipocytes (Subcutaneous)': '-0.368', 'Adipocytes (Visceral)': '-0.167', 'Breast glandular cells (progenitors)': '0.190', 'Adipocytes (Breast)': '-0.382', 'Colon enterocytes': '0.004', 'Colon enteroendocrine cells': '0.196', 'Enteric glia cells': '-0.129', 'Mitotic cells (Colon)': '0.005', 'Mitotic cells (Heart)': '0.486', 'Podocytes': '-0.114', 'Ascending Loop of Henle cells': '0.371', 'Intercalated cells': '-0.097', 'Cholangiocyte': '0.375', 'NK-cells (Liver)': '-0.278', 'Respiratory ciliated cells': '-0.022', 'Mitotic cells (Lung)': '0.157', 'NK-cells (Lung)': '0.110', 'B-cells (Lung)': '-0.155', 'Alpha cells': '0.333', 'Beta cells': '0.161', 'Prostate glandular cells': '-0.162', 'Prostate basal glandular cells': '0.286', 'Urothelial cells': '0.283', 'Keratinocyte (other)': '0.121', 'Keratinocyte (granular)': '-0.008', 'Hair cortex cells': '-0.113', 'Inner root sheath cells': '-0.069', 'Outer root sheath cells': '0.125', 'Sebaceous gland cells': '0.110', 'Eccrine sweat gland cells': '0.070', 'Adipocytes (Skin)': '0.019', 'Mitotic cells (Skin)': '0.236', 'Parietal cells': '-0.609', 'Chief cells': '-0.599', 'Gastric mucous cells': '-0.193', 'Gastric enteroendocrine cells': '-0.441', 'Mitotic cells (Stomach)': '0.261', 'Parafollicular cells': '-0.028', 'Thyroid glandular cells': '0.094', 'Mitotic cells (Thyroid)': '0.242', 'Adrenal cortex cells': '0.619', 'Adrenal medulla cells': '0.063', 'Mitotic cells (Adrenal gland)': '0.483', 'Minor salivary glandular cells': '0.582', 'Minor salivary gland ductal cells': '0.072', 'Minor salivary gland basal cells': '0.229', 'Mitotic cells (Minor salivary gland)': '0.376', 'Adipocytes (Minor salivary gland)': '0.211', 'Somatotropes': '-0.121', 'Lactotropes': '-0.287', 'Gonadotropes': '0.004', 'Corticotropes': '-0.352', 'Thyrotropes': '-0.054', 'Undifferentiated cells (Pituitary gland)': '0.486', 'Mitotic cells (Spleen)': '-0.016', 'Platelets': '0.115', 'Erythrocytes': '0.098', 'Hematopoietic stem cells': '0.042', 'B-cells (Spleen)': '0.028', 'NK-cells (Spleen)': '0.157', 'Amygdala excitatory': '0.1', 'Cerebellar inhibitory': '0.2', 'Cge interneuron': '0.3', 'Deep-layer corticothalamic and 6b': '0.3', 'Deep-layer intratelencephalic': '0.1', 'Deep-layer near-projecting': '0.1', 'Eccentric medium spiny neuron': '0.4', 'Hippocampal ca1-3': '0.5', 'Hippocampal ca4': '0.1', 'Hippocampal dentate gyrus': '0.3', 'Lamp5-lhx6 and chandelier': '0.3', 'Lower rhombic lip': '0.2', 'Mammillary body': '0.4', 'Medium spiny neuron': '0.6', 'Mge interneuron': '0.1', 'Midbrain-derived inhibitory': '0.6', 'Miscellaneous': '0.6', 'Splatter': '0.5', 'Thalamic excitatory': '1.3', 'Upper rhombic lip': '0.1', 'Upper-layer intratelencephalic': '0.1', 'Astrocyte': '1.5', 'Bergmann glia': '1.5', 'Central nervous system macrophage': '6.0', 'Choroid plexus epithelial cell': '2.9', 'Committed oligodendrocyte precursor': '1.0', 'Ependymal cell': '1.3', 'Oligodendrocyte': '0.1', 'Oligodendrocyte precursor cell': '2.3', 'Endothelial cell': '6.4', 'Pericyte': '5.3', 'Vascular associated smooth muscle cell': '3.1', 'Fibroblast': '5.3', 'Leukocyte': '7.4', 'Basophil': '107.0', 'Eosinophil': '312.5', 'Neutrophil': '496.9', 'Classical monocyte': '25.8', 'Non-classical monocyte': '66.1', 'Intermediate monocyte': '117.0', 'T-reg': '72.1', 'GdT-cell': '89.5', 'MAIT T-cell': '61.2', 'Memory CD4 T-cell': '76.8', 'Naive CD4 T-cell': '47.0', 'Memory CD8 T-cell': '81.1', 'Naive CD8 T-cell': '43.5', 'Memory B-cell': '50.4', 'Naive B-cell': '38.5', 'Plasmacytoid DC': '47.5', 'Myeloid DC': '92.2', 'NK-cell': '88.9', 'Total PBMC': '83.8', 'Vd2 gdTCR': '67.8', 'Memory CD4 T-cell Th1\\/Th17': '48.0', 'Memory CD4 T-cell Th17': '54.6', 'Memory CD4 T-cell Th2': '54.8', 'Non-Vd2 gdTCR': '73.7', 'Memory CD4 T-cell Th1': '58.8', 'Memory CD4 T-cell TFH': '61.9', 'Terminal effector memory CD4 T-cell': '72.8', 'Central memory CD8 T-cell': '59.9', 'Effector memory CD8 T-cell': '90.7', 'Terminal effector memory CD8 T-cell': '75.8', 'Non-switched memory B-cell': '52.6', 'Plasmablast': '62.3', 'Switched memory B-cell': '55.8', 'Exhausted memory B-cell': '52.1', 'Progenitor cell': '44.7', 'Memory T-reg': '82.4', 'Naive CD4 T-cell activated': '133.9', 'Naive CD8 T-cell activated': '163.4', 'Naive T-reg': '54.7'} | 2IWG, 5JPX, 5OLM, 6FGA, 6S53, 7BBD, 8A58 | {'Adipose Tissue': 21.42795099667774, 'Adrenal Gland': 16.707763565891472, 'Bladder': 21.861904761904764, 'Blood': 61.11958557588805, 'Blood Vessel': 22.62928389513109, 'Brain': 4.305000416351249, 'Breast': 20.001740740740743, 'Cervix Uteri': 26.420526315789473, 'Colon': 23.40817458279846, 'Esophagus': 21.74157577854671, 'Fallopian Tube': 25.39, 'Heart': 6.66628106852497, 'Kidney': 13.61479775280899, 'Liver': 10.388, 'Lung': 32.00464878892734, 'Muscle': 3.944284806973848, 'Nerve': 25.39305008077545, 'Ovary': 30.51811111111111, 'Pancreas': 6.808080182926829, 'Pituitary': 12.995699646643107, 'Prostate': 21.00597551020408, 'Salivary Gland': 16.434148148148147, 'Skin': 17.851811498065228, 'Small Intestine': 28.907085561497325, 'Spleen': 50.16024896265561, 'Stomach': 19.072721448467966, 'Testis': 6.377013850415512, 'Thyroid': 21.553307810107196, 'Uterus': 29.83549295774648, 'Vagina': 21.551141025641027} | CDKN1B | MSNVRVSNGSPSLERMDARQAEHPKPSACRNLFGPVDHEELTRDLEKHCRDMEEASQRKWNFDFQNHKPLEGKYEWQEVEKGSLPEFYYRPPRPPKGACKVPAQESQDVSGSRPAAPLIGAPANSEDTHLVDPKTDPSDSQTGLAEQCAGIRKRPATDDSSTQNKRANRTEENVSDGSPNAGSVEQTPKKPGLRRRQT | Homo sapiens | Nucleus, Cytoplasm, Endosome | Low tissue specificity | {'Ciliated cells': '25.5', 'Basal respiratory cells': '19.8', 'Club cells': '33.9', 'Ionocytes': '17.3', 'Mucus glandular cells': '26.7', 'Serous glandular cells': '25.5', 'Gastric mucus-secreting cells': '21.2', 'Proximal enterocytes': '32.3', 'Paneth cells': '26.7', 'Distal enterocytes': '26.4', 'Intestinal goblet cells': '43.2', 'Exocrine glandular cells': '-0.402', 'Basal prostatic cells': '53.1', 'Prostatic glandular cells': '52.2', 'Breast glandular cells': '0.569', 'Breast myoepithelial cells': '0.552', 'Glandular and luminal cells': '35.5', 'Secretory cells': '17.9', 'Basal keratinocytes': '48.9', 'Suprabasal keratinocytes': '45.4', 'Basal squamous epithelial cells': '108.4', 'Squamous epithelial cells': '94.2', 'Alveolar cells type 1': '0.268', 'Alveolar cells type 2': '-0.454', 'Salivary duct cells': '18.6', 'Ductal cells': '0.390', 'Hepatocytes': '0.427', 'Cholangiocytes': '24.8', 'Proximal tubular cells': '0.182', 'Distal tubular cells': '12.3', 'Collecting duct cells': '7.8', 'Mesothelial cells': '0.360', 'Sertoli cells': '0.710', 'Granulosa cells': '34.9', 'Enteroendocrine cells': '46.9', 'Pancreatic endocrine cells': '10.2', 'Leydig cells': '0.570', 'Excitatory neurons': '7.8', 'Inhibitory neurons': '12.8', 'Cone photoreceptor cells': '37.4', 'Rod photoreceptor cells': '22.9', 'Bipolar cells': '40.5', 'Horizontal cells': '33.4', 'Astrocytes': '5.9', 'Oligodendrocyte precursor cells': '5.7', 'Oligodendrocytes': '27.4', 'Microglial cells': '22.4', 'Muller glia cells': '161.0', 'Schwann cells': '0.203', 'Spermatogonia': '0.605', 'Spermatocytes': '0.208', 'Early spermatids': '-0.390', 'Late spermatids': '-0.600', 'Oocytes': '34.6', 'Cytotrophoblasts': '42.9', 'Syncytiotrophoblasts': '39.3', 'Extravillous trophoblasts': '47.9', 'Endothelial cells': '48.3', 'Lymphatic endothelial cells': '35.6', 'Cardiomyocytes': '0.591', 'Skeletal myocytes': '0.056', 'Smooth muscle cells': '59.7', 'Adipocytes': '59.8', 'Melanocytes': '0.231', 'Fibroblasts': '42.7', 'Peritubular cells': '0.470', 'Endometrial stromal cells': '35.7', 'Ovarian stromal cells': '41.7', 'Undifferentiated cells': '47.6', 'T-cells': '190.6', 'B-cells': '126.4', 'Plasma cells': '104.9', 'Nk-cells': '112.4', 'Granulocytes': '60.0', 'Monocytes': '214.6', 'Macrophages': '64.1', 'Hofbauer cells': '29.4', 'Kupffer cells': '45.2', 'Dendritic cells': '34.0', 'Langerhans cells': '0.223', 'Erythroid cells': '0.094', 'Adipocytes (Subcutaneous)': '-0.517', 'Adipocytes (Visceral)': '-0.477', 'Breast glandular cells (progenitors)': '0.368', 'Adipocytes (Breast)': '-0.627', 'Colon enterocytes': '-0.181', 'Colon enteroendocrine cells': '0.273', 'Enteric glia cells': '0.274', 'Mitotic cells (Colon)': '-0.154', 'Mitotic cells (Heart)': '0.432', 'Podocytes': '0.231', 'Ascending Loop of Henle cells': '0.387', 'Intercalated cells': '0.157', 'Cholangiocyte': '0.289', 'NK-cells (Liver)': '-0.151', 'Respiratory ciliated cells': '0.124', 'Mitotic cells (Lung)': '-0.198', 'NK-cells (Lung)': '0.460', 'B-cells (Lung)': '0.301', 'Alpha cells': '0.322', 'Beta cells': '0.167', 'Prostate glandular cells': '-0.143', 'Prostate basal glandular cells': '-0.077', 'Urothelial cells': '-0.007', 'Keratinocyte (other)': '0.422', 'Keratinocyte (granular)': '-0.212', 'Hair cortex cells': '-0.070', 'Inner root sheath cells': '0.013', 'Outer root sheath cells': '0.228', 'Sebaceous gland cells': '-0.068', 'Eccrine sweat gland cells': '0.016', 'Adipocytes (Skin)': '-0.310', 'Mitotic cells (Skin)': '0.433', 'Parietal cells': '-0.533', 'Chief cells': '-0.430', 'Gastric mucous cells': '-0.374', 'Gastric enteroendocrine cells': '-0.297', 'Mitotic cells (Stomach)': '-0.041', 'Parafollicular cells': '0.037', 'Thyroid glandular cells': '0.270', 'Mitotic cells (Thyroid)': '0.117', 'Adrenal cortex cells': '0.464', 'Adrenal medulla cells': '0.086', 'Mitotic cells (Adrenal gland)': '0.262', 'Minor salivary glandular cells': '0.329', 'Minor salivary gland ductal cells': '0.195', 'Minor salivary gland basal cells': '0.233', 'Mitotic cells (Minor salivary gland)': '0.325', 'Adipocytes (Minor salivary gland)': '0.264', 'Somatotropes': '-0.125', 'Lactotropes': '-0.147', 'Gonadotropes': '0.003', 'Corticotropes': '-0.198', 'Thyrotropes': '0.077', 'Undifferentiated cells (Pituitary gland)': '0.405', 'Mitotic cells (Spleen)': '-0.100', 'Platelets': '-0.172', 'Erythrocytes': '-0.125', 'Hematopoietic stem cells': '-0.154', 'B-cells (Spleen)': '0.316', 'NK-cells (Spleen)': '0.264', 'Amygdala excitatory': '7.2', 'Cerebellar inhibitory': '17.8', 'Cge interneuron': '24.8', 'Deep-layer corticothalamic and 6b': '7.4', 'Deep-layer intratelencephalic': '8.1', 'Deep-layer near-projecting': '6.0', 'Eccentric medium spiny neuron': '7.2', 'Hippocampal ca1-3': '6.8', 'Hippocampal ca4': '7.4', 'Hippocampal dentate gyrus': '7.4', 'Lamp5-lhx6 and chandelier': '21.3', 'Lower rhombic lip': '16.1', 'Mammillary body': '17.5', 'Medium spiny neuron': '7.2', 'Mge interneuron': '18.5', 'Midbrain-derived inhibitory': '21.4', 'Miscellaneous': '8.8', 'Splatter': '14.0', 'Thalamic excitatory': '13.8', 'Upper rhombic lip': '38.3', 'Upper-layer intratelencephalic': '7.4', 'Astrocyte': '10.5', 'Bergmann glia': '20.7', 'Central nervous system macrophage': '22.7', 'Choroid plexus epithelial cell': '13.8', 'Committed oligodendrocyte precursor': '20.0', 'Ependymal cell': '19.3', 'Oligodendrocyte': '39.1', 'Oligodendrocyte precursor cell': '18.7', 'Endothelial cell': '55.0', 'Pericyte': '61.5', 'Vascular associated smooth muscle cell': '58.1', 'Fibroblast': '28.4', 'Leukocyte': '63.4', 'Basophil': '146.3', 'Eosinophil': '8.2', 'Neutrophil': '108.3', 'Classical monocyte': '115.3', 'Non-classical monocyte': '165.4', 'Intermediate monocyte': '55.0', 'T-reg': '96.6', 'GdT-cell': '5.8', 'MAIT T-cell': '112.3', 'Memory CD4 T-cell': '7.5', 'Naive CD4 T-cell': '437.3', 'Memory CD8 T-cell': '6.9', 'Naive CD8 T-cell': '336.0', 'Memory B-cell': '6.7', 'Naive B-cell': '180.8', 'Plasmacytoid DC': '17.6', 'Myeloid DC': '69.7', 'NK-cell': '141.8', 'Total PBMC': '64.5', 'Vd2 gdTCR': '53.3', 'Memory CD4 T-cell Th1\\/Th17': '454.5', 'Memory CD4 T-cell Th17': '375.9', 'Memory CD4 T-cell Th2': '438.1', 'Non-Vd2 gdTCR': '73.3', 'Memory CD4 T-cell Th1': '377.8', 'Memory CD4 T-cell TFH': '436.6', 'Terminal effector memory CD4 T-cell': '50.5', 'Central memory CD8 T-cell': '100.1', 'Effector memory CD8 T-cell': '58.9', 'Terminal effector memory CD8 T-cell': '54.5', 'Non-switched memory B-cell': '46.9', 'Plasmablast': '53.8', 'Switched memory B-cell': '50.0', 'Exhausted memory B-cell': '46.7', 'Progenitor cell': '20.4', 'Memory T-reg': '447.2', 'Naive CD4 T-cell activated': '97.4', 'Naive CD8 T-cell activated': '93.6', 'Naive T-reg': '713.8'} | 1H27, 1JSU, 2AST, 5UQ3, 6ATH, 6P8E, 6P8F, 6P8G, 7B5L, 7B5M, 7B5R, 7OR8, 7ORG, 7ORH, 7ORS, 7ORT, 8BYA, 8BYL, 8BZO | {'Adipose Tissue': 89.28307308970099, 'Adrenal Gland': 49.201007751937986, 'Bladder': 63.78047619047619, 'Blood': 68.55482454251884, 'Blood Vessel': 122.23632958801498, 'Brain': 69.23933762301286, 'Breast': 97.70257080610024, 'Cervix Uteri': 117.59052631578946, 'Colon': 69.30115532734274, 'Esophagus': 56.005737024221446, 'Fallopian Tube': 110.25333333333332, 'Heart': 23.158851335656216, 'Kidney': 27.414337078651688, 'Liver': 24.55152654867257, 'Lung': 82.52216262975779, 'Muscle': 43.84146575342466, 'Nerve': 139.4383198707593, 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0.87, 0.99] | RING finger | Component of a SCF(SKP2)-like complex containing CUL1, SKP1, TRIM21 and SKP2. | SCF | null | IRF8, CALR, CUL1, FBXW11, HSPA5, IKBKB, IRF3, SKP1 , VCP,SKP2, DCP2 ,ULK1, BECN1,GABARAP, GABARAPL1, GABARAPL2 , MAP1LC3C,SQSTM1,IRF3 , NMI, IFI35 , CUL1, TRIM21 | USP4, IKBKB, TRIM21, CDKN1B, IRF3, IRF8, MNI | mono, 63 | null | UBE2D2, UBE2D1, UBE2E1, UBE2E2 | Homotrimer | null | 90.718042 | 0.406716 | 69.051313 | 0.809899 | 2,742 |
P19474 | P49915 | 33742136 | UbiBrowser | TRIM21 | MASAARLTMMWEEVTCPICLDPFVEPVSIECGHSFCQECISQVGKGGGSVCPVCRQRFLLKNLRPNRQLANMVNNLKEISQEAREGTQGERCAVHGERLHLFCEKDGKALCWVCAQSRKHRDHAMVPLEEAAQEYQEKLQVALGELRRKQELAEKLEVEIAIKRADWKKTVETQKSRIHAEFVQQKNFLVEEEQRQLQELEKDEREQLRILGEKEAKLAQQSQALQELISELDRRCHSSALELLQEVIIVLERSESWNLKDLDITSPELRSVCHVPGLKKMLRTCAVHITLDPDTANPWLILSEDRRQVRLGDTQQSIPGNEERFDSYPMVLGAQHFHSGKHYWEVDVTGKEAWDLGVCRDSVRRKGHFLLSSKSGFWTIWLWNKQKYEAGTYPQTPLHLQVPPCQVGIFLDYEAGMVSFYNITDHGSLIYSFSECAFTGPLRPFFSPGFNDGGKNTAPLTLCPLNIGSQGSTDY | Homo sapiens | Cytoplasm, Cytoplasmic vesicle, autophagosome, Nucleus, Cytoplasm, P-body, Cytoplasm, Stress granule | Low tissue specificity | {'Ciliated cells': '3.8', 'Basal respiratory cells': '6.8', 'Club cells': '5.8', 'Ionocytes': '3.7', 'Mucus glandular cells': '4.8', 'Serous glandular cells': '2.3', 'Gastric mucus-secreting cells': '8.8', 'Proximal enterocytes': '8.9', 'Paneth cells': '3.9', 'Distal enterocytes': '8.5', 'Intestinal goblet cells': '8.4', 'Exocrine glandular cells': '-0.716', 'Basal prostatic cells': '5.4', 'Prostatic glandular cells': '5.0', 'Breast glandular cells': '0.298', 'Breast myoepithelial cells': '0.351', 'Glandular and luminal cells': '5.9', 'Secretory cells': '8.4', 'Basal keratinocytes': '3.2', 'Suprabasal keratinocytes': '2.7', 'Basal squamous epithelial cells': '6.4', 'Squamous epithelial cells': '4.3', 'Alveolar cells type 1': '0.116', 'Alveolar cells type 2': '0.115', 'Salivary duct cells': '3.0', 'Ductal cells': '0.700', 'Hepatocytes': '0.503', 'Cholangiocytes': '11.4', 'Proximal tubular cells': '0.175', 'Distal tubular cells': '0.0', 'Collecting duct cells': '5.8', 'Mesothelial cells': '0.451', 'Sertoli cells': '0.479', 'Granulosa cells': '4.8', 'Enteroendocrine cells': '3.7', 'Pancreatic endocrine cells': '3.4', 'Leydig cells': '0.632', 'Excitatory neurons': '0.2', 'Inhibitory neurons': '0.1', 'Cone photoreceptor cells': '0.0', 'Rod photoreceptor cells': '0.0', 'Bipolar cells': '0.7', 'Horizontal cells': '0.6', 'Astrocytes': '0.0', 'Oligodendrocyte precursor cells': '0.9', 'Oligodendrocytes': '0.1', 'Microglial cells': '1.8', 'Muller glia cells': '2.4', 'Schwann cells': '0.099', 'Spermatogonia': '0.401', 'Spermatocytes': '-0.062', 'Early spermatids': '-0.578', 'Late spermatids': '-0.618', 'Oocytes': '1.5', 'Cytotrophoblasts': '6.6', 'Syncytiotrophoblasts': '9.8', 'Extravillous trophoblasts': '10.0', 'Endothelial cells': '7.8', 'Lymphatic endothelial cells': '6.9', 'Cardiomyocytes': '0.335', 'Skeletal myocytes': '-0.080', 'Smooth muscle cells': '6.3', 'Adipocytes': '8.3', 'Melanocytes': '0.101', 'Fibroblasts': '6.5', 'Peritubular cells': '0.579', 'Endometrial stromal cells': '4.5', 'Ovarian stromal cells': '6.7', 'Undifferentiated cells': '5.9', 'T-cells': '9.9', 'B-cells': '8.8', 'Plasma cells': '5.0', 'Nk-cells': '15.1', 'Granulocytes': '6.2', 'Monocytes': '7.8', 'Macrophages': '8.5', 'Hofbauer cells': '9.9', 'Kupffer cells': '10.3', 'Dendritic cells': '8.0', 'Langerhans cells': '0.466', 'Erythroid cells': '-0.084', 'Adipocytes (Subcutaneous)': '-0.368', 'Adipocytes (Visceral)': '-0.167', 'Breast glandular cells (progenitors)': '0.190', 'Adipocytes (Breast)': '-0.382', 'Colon enterocytes': '0.004', 'Colon enteroendocrine cells': '0.196', 'Enteric glia cells': '-0.129', 'Mitotic cells (Colon)': '0.005', 'Mitotic cells (Heart)': '0.486', 'Podocytes': '-0.114', 'Ascending Loop of Henle cells': '0.371', 'Intercalated cells': '-0.097', 'Cholangiocyte': '0.375', 'NK-cells (Liver)': '-0.278', 'Respiratory ciliated cells': '-0.022', 'Mitotic cells (Lung)': '0.157', 'NK-cells (Lung)': '0.110', 'B-cells (Lung)': '-0.155', 'Alpha cells': '0.333', 'Beta cells': '0.161', 'Prostate glandular cells': '-0.162', 'Prostate basal glandular cells': '0.286', 'Urothelial cells': '0.283', 'Keratinocyte (other)': '0.121', 'Keratinocyte (granular)': '-0.008', 'Hair cortex cells': '-0.113', 'Inner root sheath cells': '-0.069', 'Outer root sheath cells': '0.125', 'Sebaceous gland cells': '0.110', 'Eccrine sweat gland cells': '0.070', 'Adipocytes (Skin)': '0.019', 'Mitotic cells (Skin)': '0.236', 'Parietal cells': '-0.609', 'Chief cells': '-0.599', 'Gastric mucous cells': '-0.193', 'Gastric enteroendocrine cells': '-0.441', 'Mitotic cells (Stomach)': '0.261', 'Parafollicular cells': '-0.028', 'Thyroid glandular cells': '0.094', 'Mitotic cells (Thyroid)': '0.242', 'Adrenal cortex cells': '0.619', 'Adrenal medulla cells': '0.063', 'Mitotic cells (Adrenal gland)': '0.483', 'Minor salivary glandular cells': '0.582', 'Minor salivary gland ductal cells': '0.072', 'Minor salivary gland basal cells': '0.229', 'Mitotic cells (Minor salivary gland)': '0.376', 'Adipocytes (Minor salivary gland)': '0.211', 'Somatotropes': '-0.121', 'Lactotropes': '-0.287', 'Gonadotropes': '0.004', 'Corticotropes': '-0.352', 'Thyrotropes': '-0.054', 'Undifferentiated cells (Pituitary gland)': '0.486', 'Mitotic cells (Spleen)': '-0.016', 'Platelets': '0.115', 'Erythrocytes': '0.098', 'Hematopoietic stem cells': '0.042', 'B-cells (Spleen)': '0.028', 'NK-cells (Spleen)': '0.157', 'Amygdala excitatory': '0.1', 'Cerebellar inhibitory': '0.2', 'Cge interneuron': '0.3', 'Deep-layer corticothalamic and 6b': '0.3', 'Deep-layer intratelencephalic': '0.1', 'Deep-layer near-projecting': '0.1', 'Eccentric medium spiny neuron': '0.4', 'Hippocampal ca1-3': '0.5', 'Hippocampal ca4': '0.1', 'Hippocampal dentate gyrus': '0.3', 'Lamp5-lhx6 and chandelier': '0.3', 'Lower rhombic lip': '0.2', 'Mammillary body': '0.4', 'Medium spiny neuron': '0.6', 'Mge interneuron': '0.1', 'Midbrain-derived inhibitory': '0.6', 'Miscellaneous': '0.6', 'Splatter': '0.5', 'Thalamic excitatory': '1.3', 'Upper rhombic lip': '0.1', 'Upper-layer intratelencephalic': '0.1', 'Astrocyte': '1.5', 'Bergmann glia': '1.5', 'Central nervous system macrophage': '6.0', 'Choroid plexus epithelial cell': '2.9', 'Committed oligodendrocyte precursor': '1.0', 'Ependymal cell': '1.3', 'Oligodendrocyte': '0.1', 'Oligodendrocyte precursor cell': '2.3', 'Endothelial cell': '6.4', 'Pericyte': '5.3', 'Vascular associated smooth muscle cell': '3.1', 'Fibroblast': '5.3', 'Leukocyte': '7.4', 'Basophil': '107.0', 'Eosinophil': '312.5', 'Neutrophil': '496.9', 'Classical monocyte': '25.8', 'Non-classical monocyte': '66.1', 'Intermediate monocyte': '117.0', 'T-reg': '72.1', 'GdT-cell': '89.5', 'MAIT T-cell': '61.2', 'Memory CD4 T-cell': '76.8', 'Naive CD4 T-cell': '47.0', 'Memory CD8 T-cell': '81.1', 'Naive CD8 T-cell': '43.5', 'Memory B-cell': '50.4', 'Naive B-cell': '38.5', 'Plasmacytoid DC': '47.5', 'Myeloid DC': '92.2', 'NK-cell': '88.9', 'Total PBMC': '83.8', 'Vd2 gdTCR': '67.8', 'Memory CD4 T-cell Th1\\/Th17': '48.0', 'Memory CD4 T-cell Th17': '54.6', 'Memory CD4 T-cell Th2': '54.8', 'Non-Vd2 gdTCR': '73.7', 'Memory CD4 T-cell Th1': '58.8', 'Memory CD4 T-cell TFH': '61.9', 'Terminal effector memory CD4 T-cell': '72.8', 'Central memory CD8 T-cell': '59.9', 'Effector memory CD8 T-cell': '90.7', 'Terminal effector memory CD8 T-cell': '75.8', 'Non-switched memory B-cell': '52.6', 'Plasmablast': '62.3', 'Switched memory B-cell': '55.8', 'Exhausted memory B-cell': '52.1', 'Progenitor cell': '44.7', 'Memory T-reg': '82.4', 'Naive CD4 T-cell activated': '133.9', 'Naive CD8 T-cell activated': '163.4', 'Naive T-reg': '54.7'} | 2IWG, 5JPX, 5OLM, 6FGA, 6S53, 7BBD, 8A58 | {'Adipose Tissue': 21.42795099667774, 'Adrenal Gland': 16.707763565891472, 'Bladder': 21.861904761904764, 'Blood': 61.11958557588805, 'Blood Vessel': 22.62928389513109, 'Brain': 4.305000416351249, 'Breast': 20.001740740740743, 'Cervix Uteri': 26.420526315789473, 'Colon': 23.40817458279846, 'Esophagus': 21.74157577854671, 'Fallopian Tube': 25.39, 'Heart': 6.66628106852497, 'Kidney': 13.61479775280899, 'Liver': 10.388, 'Lung': 32.00464878892734, 'Muscle': 3.944284806973848, 'Nerve': 25.39305008077545, 'Ovary': 30.51811111111111, 'Pancreas': 6.808080182926829, 'Pituitary': 12.995699646643107, 'Prostate': 21.00597551020408, 'Salivary Gland': 16.434148148148147, 'Skin': 17.851811498065228, 'Small Intestine': 28.907085561497325, 'Spleen': 50.16024896265561, 'Stomach': 19.072721448467966, 'Testis': 6.377013850415512, 'Thyroid': 21.553307810107196, 'Uterus': 29.83549295774648, 'Vagina': 21.551141025641027} | GMPS | MALCNGDSKLENAGGDLKDGHHHYEGAVVILDAGAQYGKVIDRRVRELFVQSEIFPLETPAFAIKEQGFRAIIISGGPNSVYAEDAPWFDPAIFTIGKPVLGICYGMQMMNKVFGGTVHKKSVREDGVFNISVDNTCSLFRGLQKEEVVLLTHGDSVDKVADGFKVVARSGNIVAGIANESKKLYGAQFHPEVGLTENGKVILKNFLYDIAGCSGTFTVQNRELECIREIKERVGTSKVLVLLSGGVDSTVCTALLNRALNQEQVIAVHIDNGFMRKRESQSVEEALKKLGIQVKVINAAHSFYNGTTTLPISDEDRTPRKRISKTLNMTTSPEEKRKIIGDTFVKIANEVIGEMNLKPEEVFLAQGTLRPDLIESASLVASGKAELIKTHHNDTELIRKLREEGKVIEPLKDFHKDEVRILGRELGLPEELVSRHPFPGPGLAIRVICAEEPYICKDFPETNNILKIVADFSASVKKPHTLLQRVKACTTEEDQEKLMQITSLHSLNAFLLPIKTVGVQGDCRSYSYVCGISSKDEPDWESLIFLARLIPRMCHNVNRVVYIFGPPVKEPPTDVTPTFLTTGVLSTLRQADFEAHNILRESGYAGKISQMPVILTPLHFDRDPLQKQPSCQRSVVIRTFITSDFMTGIPATPGNEIPVEVVLKMVTEIKKIPGISRIMYDLTSKPPGTTEWE | Homo sapiens | Cytoplasm, cytosol | Tissue enhanced (testis) | {'Ciliated cells': '14.9', 'Basal respiratory cells': '36.4', 'Club cells': '25.1', 'Ionocytes': '18.4', 'Mucus glandular cells': '23.6', 'Serous glandular cells': '41.2', 'Gastric mucus-secreting cells': '22.4', 'Proximal enterocytes': '17.6', 'Paneth cells': '9.1', 'Distal enterocytes': '11.4', 'Intestinal goblet cells': '21.8', 'Exocrine glandular cells': '-0.617', 'Basal prostatic cells': '30.8', 'Prostatic glandular cells': '31.6', 'Breast glandular cells': '0.501', 'Breast myoepithelial cells': '0.571', 'Glandular and luminal cells': '17.6', 'Secretory cells': '36.7', 'Basal keratinocytes': '38.2', 'Suprabasal keratinocytes': '37.3', 'Basal squamous epithelial cells': '31.2', 'Squamous epithelial cells': '25.2', 'Alveolar cells type 1': '0.072', 'Alveolar cells type 2': '-0.155', 'Salivary duct cells': '31.4', 'Ductal cells': '0.462', 'Hepatocytes': '0.551', 'Cholangiocytes': '11.4', 'Proximal tubular cells': '0.158', 'Distal tubular cells': '15.4', 'Collecting duct cells': '9.7', 'Mesothelial cells': '0.457', 'Sertoli cells': '-0.258', 'Granulosa cells': '22.4', 'Enteroendocrine cells': '15.3', 'Pancreatic endocrine cells': '35.7', 'Leydig cells': '-0.340', 'Excitatory neurons': '39.5', 'Inhibitory neurons': '39.9', 'Cone photoreceptor cells': '10.2', 'Rod photoreceptor cells': '5.0', 'Bipolar cells': '16.6', 'Horizontal cells': '20.1', 'Astrocytes': '18.6', 'Oligodendrocyte precursor cells': '28.3', 'Oligodendrocytes': '29.4', 'Microglial cells': '21.5', 'Muller glia cells': '16.5', 'Schwann cells': '0.137', 'Spermatogonia': '0.002', 'Spermatocytes': '0.380', 'Early spermatids': '0.866', 'Late spermatids': '0.438', 'Oocytes': '63.2', 'Cytotrophoblasts': '44.1', 'Syncytiotrophoblasts': '29.3', 'Extravillous trophoblasts': '50.3', 'Endothelial cells': '27.0', 'Lymphatic endothelial cells': '27.1', 'Cardiomyocytes': '0.591', 'Skeletal myocytes': '-0.284', 'Smooth muscle cells': '29.0', 'Adipocytes': '21.0', 'Melanocytes': '0.247', 'Fibroblasts': '29.1', 'Peritubular cells': '-0.225', 'Endometrial stromal cells': '35.6', 'Ovarian stromal cells': '20.7', 'Undifferentiated cells': '40.6', 'T-cells': '31.8', 'B-cells': '23.0', 'Plasma cells': '22.3', 'Nk-cells': '23.8', 'Granulocytes': '30.8', 'Monocytes': '25.4', 'Macrophages': '24.2', 'Hofbauer cells': '25.4', 'Kupffer cells': '12.8', 'Dendritic cells': '20.6', 'Langerhans cells': '0.270', 'Erythroid cells': '-0.067', 'Adipocytes (Subcutaneous)': '-0.392', 'Adipocytes (Visceral)': '-0.416', 'Breast glandular cells (progenitors)': '0.393', 'Adipocytes (Breast)': '-0.562', 'Colon enterocytes': '-0.150', 'Colon enteroendocrine cells': '0.256', 'Enteric glia cells': '0.046', 'Mitotic cells (Colon)': '-0.039', 'Mitotic cells (Heart)': '0.518', 'Podocytes': '-0.063', 'Ascending Loop of Henle cells': '0.435', 'Intercalated cells': '0.027', 'Cholangiocyte': '0.339', 'NK-cells (Liver)': '-0.311', 'Respiratory ciliated cells': '-0.100', 'Mitotic cells (Lung)': '0.054', 'NK-cells (Lung)': '0.176', 'B-cells (Lung)': '0.016', 'Alpha cells': '0.328', 'Beta cells': '0.155', 'Prostate glandular cells': '-0.242', 'Prostate basal glandular cells': '0.119', 'Urothelial cells': '0.161', 'Keratinocyte (other)': '0.485', 'Keratinocyte (granular)': '-0.126', 'Hair cortex cells': '-0.137', 'Inner root sheath cells': '-0.035', 'Outer root sheath cells': '0.032', 'Sebaceous gland cells': '0.042', 'Eccrine sweat gland cells': '-0.117', 'Adipocytes (Skin)': '-0.279', 'Mitotic cells (Skin)': '0.374', 'Parietal cells': '-0.590', 'Chief cells': '-0.395', 'Gastric mucous cells': '-0.340', 'Gastric enteroendocrine cells': '-0.328', 'Mitotic cells (Stomach)': '0.094', 'Parafollicular cells': '0.110', 'Thyroid glandular cells': '0.361', 'Mitotic cells (Thyroid)': '0.009', 'Adrenal cortex cells': '0.626', 'Adrenal medulla cells': '0.055', 'Mitotic cells (Adrenal gland)': '0.373', 'Minor salivary glandular cells': '0.403', 'Minor salivary gland ductal cells': '0.193', 'Minor salivary gland basal cells': '0.415', 'Mitotic cells (Minor salivary gland)': '0.310', 'Adipocytes (Minor salivary gland)': '0.087', 'Somatotropes': '0.052', 'Lactotropes': '0.119', 'Gonadotropes': '0.023', 'Corticotropes': '-0.115', 'Thyrotropes': '0.172', 'Undifferentiated cells (Pituitary gland)': '0.125', 'Mitotic cells (Spleen)': '-0.103', 'Platelets': '-0.182', 'Erythrocytes': '-0.065', 'Hematopoietic stem cells': '-0.199', 'B-cells (Spleen)': '0.251', 'NK-cells (Spleen)': '0.256', 'Amygdala excitatory': '46.8', 'Cerebellar inhibitory': '74.7', 'Cge interneuron': '62.5', 'Deep-layer corticothalamic and 6b': '52.3', 'Deep-layer intratelencephalic': '44.8', 'Deep-layer near-projecting': '51.4', 'Eccentric medium spiny neuron': '65.8', 'Hippocampal ca1-3': '51.9', 'Hippocampal ca4': '38.7', 'Hippocampal dentate gyrus': '54.8', 'Lamp5-lhx6 and chandelier': '60.0', 'Lower rhombic lip': '70.0', 'Mammillary body': '81.7', 'Medium spiny neuron': '61.6', 'Mge interneuron': '58.5', 'Midbrain-derived inhibitory': '47.8', 'Miscellaneous': '56.4', 'Splatter': '59.9', 'Thalamic excitatory': '64.8', 'Upper rhombic lip': '106.2', 'Upper-layer intratelencephalic': '48.4', 'Astrocyte': '54.5', 'Bergmann glia': '62.8', 'Central nervous system macrophage': '68.4', 'Choroid plexus epithelial cell': '134.2', 'Committed oligodendrocyte precursor': '44.0', 'Ependymal cell': '53.6', 'Oligodendrocyte': '52.1', 'Oligodendrocyte precursor cell': '59.9', 'Endothelial cell': '58.3', 'Pericyte': '68.6', 'Vascular associated smooth muscle cell': '59.6', 'Fibroblast': '61.5', 'Leukocyte': '65.1', 'Basophil': '41.5', 'Eosinophil': '11.5', 'Neutrophil': '4.3', 'Classical monocyte': '12.0', 'Non-classical monocyte': '24.8', 'Intermediate monocyte': '69.5', 'T-reg': '68.6', 'GdT-cell': '24.7', 'MAIT T-cell': '80.7', 'Memory CD4 T-cell': '23.6', 'Naive CD4 T-cell': '31.0', 'Memory CD8 T-cell': '22.3', 'Naive CD8 T-cell': '24.1', 'Memory B-cell': '16.0', 'Naive B-cell': '17.0', 'Plasmacytoid DC': '76.5', 'Myeloid DC': '67.9', 'NK-cell': '27.1', 'Total PBMC': '55.1', 'Vd2 gdTCR': '72.8', 'Memory CD4 T-cell TFH': '25.1', 'Memory CD4 T-cell Th2': '31.8', 'Memory CD4 T-cell Th17': '30.8', 'Memory CD4 T-cell Th1\\/Th17': '32.6', 'Non-Vd2 gdTCR': '73.6', 'Memory CD4 T-cell Th1': '27.4', 'Terminal effector memory CD4 T-cell': '75.5', 'Central memory CD8 T-cell': '71.2', 'Effector memory CD8 T-cell': '77.9', 'Terminal effector memory CD8 T-cell': '66.8', 'Switched memory B-cell': '51.5', 'Plasmablast': '42.8', 'Non-switched memory B-cell': '46.7', 'Exhausted memory B-cell': '50.8', 'Progenitor cell': '64.3', 'Naive CD4 T-cell activated': '33.3', 'Naive CD8 T-cell activated': '34.2', 'Memory T-reg': '24.9', 'Naive T-reg': '29.4'} | 2VPI, 2VXO | {'Adipose Tissue': 12.93343438538206, 'Adrenal Gland': 12.16782945736434, 'Bladder': 14.530666666666669, 'Blood': 9.262314854682456, 'Blood Vessel': 17.065539325842696, 'Brain': 8.396625738077214, 'Breast': 13.67073202614379, 'Cervix Uteri': 20.30421052631579, 'Colon': 11.627983311938385, 'Esophagus': 12.070811764705883, 'Fallopian Tube': 17.040000000000003, 'Heart': 5.010834262485482, 'Kidney': 5.67808988764045, 'Liver': 3.8461734513274335, 'Lung': 13.950162629757786, 'Muscle': 5.950008717310087, 'Nerve': 20.056009693053312, 'Ovary': 17.43597777777778, 'Pancreas': 6.603685975609756, 'Pituitary': 11.949074204946998, 'Prostate': 12.952408163265307, 'Salivary Gland': 12.453222222222225, 'Skin': 18.792415699281374, 'Small Intestine': 10.038604278074867, 'Spleen': 10.509095435684648, 'Stomach': 9.599855153203343, 'Testis': 51.16567867036011, 'Thyroid': 14.286551301684533, 'Uterus': 19.476690140845072, 'Vagina': 17.100416666666668} | [37.42, 45.2, 56.71, 57.57, 65.92, 71.8, 70.72, 70.19, 75.03, 81.06, 81.95, 82.13, 85.0, 89.84, 89.65, 93.29, 90.82, 89.33, 90.46, 84.59, 85.8, 87.81, 91.19, 89.54, 92.34, 94.82, 95.66, 94.94, 93.26, 90.29, 93.55, 91.65, 95.23, 95.54, 95.57, 95.25, 94.22, 93.77, 94.59, 93.99, 92.38, 92.01, 90.02, 87.48, 84.99, 84.15, 85.0, 86.86, 92.88, 92.09, 93.98, 92.61, 92.26, 94.16, 91.11, 93.0, 91.84, 92.37, 91.85, 87.92, 88.9, 90.86, 91.4, 93.27, 94.09, 93.72, 91.24, 89.47, 90.87, 89.3, 89.1, 89.45, 87.1, 86.17, 84.68, 82.73, 79.4, 75.43, 73.11, 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0.14, 0.42, 0.06, 0.0, 0.58, 0.09, 0.03, 0.07, 0.48, 0.01, 0.18, 0.38, 0.17, 0.36, 0.81, 0.77, 0.93, 0.55, 0.82, 0.16, 0.05, 0.65, 0.49, 0.01, 0.32, 0.78, 0.43, 0.12, 0.56, 0.78, 0.76, 0.12, 0.21, 0.69, 0.43, 0.0, 0.35, 0.6, 0.05, 0.08, 0.7, 0.75, 0.27, 0.52, 0.14, 0.39, 0.09, 0.05, 0.02, 0.0, 0.0, 0.02, 0.44, 0.0, 0.04, 0.01, 0.33, 0.7, 0.78, 0.91, 0.68, 0.58, 0.21, 0.3, 0.16, 0.02, 0.0, 0.0, 0.0, 0.01, 0.0, 0.06, 0.78, 0.6, 0.93, 0.24, 0.37, 0.08, 0.61, 0.11, 0.02, 0.06, 0.14, 0.03, 0.03, 0.58, 0.01, 0.02, 0.12, 0.51, 0.1, 0.06, 0.74, 0.21, 0.02, 0.04, 0.0, 0.0, 0.0, 0.04, 0.0, 0.11, 0.64, 0.75, 0.32, 0.03, 0.89, 0.64, 0.38, 0.03, 0.66, 0.4, 0.08, 0.03, 0.51, 0.0, 0.15, 0.01, 0.34, 0.67, 0.54, 0.06, 0.04, 0.54, 0.22, 0.0, 0.24, 0.29, 0.0, 0.03, 0.26, 0.25, 0.0, 0.19, 0.22, 0.05, 0.01, 0.48, 0.63, 0.3, 0.67, 0.24, 0.27, 0.89, 0.6, 0.03, 0.24, 0.1, 0.01, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.08, 0.03, 0.6, 0.18, 0.39, 0.61, 0.87, 0.61, 0.84, 0.47, 0.74, 0.15, 0.64, 0.34, 0.2, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.22, 0.19, 0.8, 0.43, 0.37, 0.61, 0.51, 0.1, 0.43, 0.03, 0.0, 0.1, 0.06, 0.66, 0.76, 0.28, 0.01, 0.15, 0.33, 0.71, 0.11, 0.0, 0.44, 0.45, 0.0, 0.12, 0.57, 0.34, 0.0, 0.45, 0.61, 0.1, 0.83, 0.38, 0.04, 0.07, 0.04, 0.03, 0.0, 0.0, 0.0, 0.02, 0.0, 0.24, 0.2, 0.65, 0.25, 0.0, 0.16, 0.14, 0.13, 0.01, 0.03] | RING finger | Component of a SCF(SKP2)-like complex containing CUL1, SKP1, TRIM21 and SKP2. | SCF | null | IRF8, CALR, CUL1, FBXW11, HSPA5, IKBKB, IRF3, SKP1 , VCP,SKP2, DCP2 ,ULK1, BECN1,GABARAP, GABARAPL1, GABARAPL2 , MAP1LC3C,SQSTM1,IRF3 , NMI, IFI35 , CUL1, TRIM21 | USP4, IKBKB, TRIM21, CDKN1B, IRF3, IRF8, MNI | mono, 63 | null | UBE2D2, UBE2D1, UBE2E1, UBE2E2 | Homotrimer | null | 90.718042 | 0.406716 | 86.651674 | 0.301227 | 1,039 |
P19474 | Q02556 | 17579016, 19494276, BioGrid E3Net | UbiNet, UbiBrowser, 31181401 | TRIM21 | MASAARLTMMWEEVTCPICLDPFVEPVSIECGHSFCQECISQVGKGGGSVCPVCRQRFLLKNLRPNRQLANMVNNLKEISQEAREGTQGERCAVHGERLHLFCEKDGKALCWVCAQSRKHRDHAMVPLEEAAQEYQEKLQVALGELRRKQELAEKLEVEIAIKRADWKKTVETQKSRIHAEFVQQKNFLVEEEQRQLQELEKDEREQLRILGEKEAKLAQQSQALQELISELDRRCHSSALELLQEVIIVLERSESWNLKDLDITSPELRSVCHVPGLKKMLRTCAVHITLDPDTANPWLILSEDRRQVRLGDTQQSIPGNEERFDSYPMVLGAQHFHSGKHYWEVDVTGKEAWDLGVCRDSVRRKGHFLLSSKSGFWTIWLWNKQKYEAGTYPQTPLHLQVPPCQVGIFLDYEAGMVSFYNITDHGSLIYSFSECAFTGPLRPFFSPGFNDGGKNTAPLTLCPLNIGSQGSTDY | Homo sapiens | Cytoplasm, Cytoplasmic vesicle, autophagosome, Nucleus, Cytoplasm, P-body, Cytoplasm, Stress granule | Low tissue specificity | {'Ciliated cells': '3.8', 'Basal respiratory cells': '6.8', 'Club cells': '5.8', 'Ionocytes': '3.7', 'Mucus glandular cells': '4.8', 'Serous glandular cells': '2.3', 'Gastric mucus-secreting cells': '8.8', 'Proximal enterocytes': '8.9', 'Paneth cells': '3.9', 'Distal enterocytes': '8.5', 'Intestinal goblet cells': '8.4', 'Exocrine glandular cells': '-0.716', 'Basal prostatic cells': '5.4', 'Prostatic glandular cells': '5.0', 'Breast glandular cells': '0.298', 'Breast myoepithelial cells': '0.351', 'Glandular and luminal cells': '5.9', 'Secretory cells': '8.4', 'Basal keratinocytes': '3.2', 'Suprabasal keratinocytes': '2.7', 'Basal squamous epithelial cells': '6.4', 'Squamous epithelial cells': '4.3', 'Alveolar cells type 1': '0.116', 'Alveolar cells type 2': '0.115', 'Salivary duct cells': '3.0', 'Ductal cells': '0.700', 'Hepatocytes': '0.503', 'Cholangiocytes': '11.4', 'Proximal tubular cells': '0.175', 'Distal tubular cells': '0.0', 'Collecting duct cells': '5.8', 'Mesothelial cells': '0.451', 'Sertoli cells': '0.479', 'Granulosa cells': '4.8', 'Enteroendocrine cells': '3.7', 'Pancreatic endocrine cells': '3.4', 'Leydig cells': '0.632', 'Excitatory neurons': '0.2', 'Inhibitory neurons': '0.1', 'Cone photoreceptor cells': '0.0', 'Rod photoreceptor cells': '0.0', 'Bipolar cells': '0.7', 'Horizontal cells': '0.6', 'Astrocytes': '0.0', 'Oligodendrocyte precursor cells': '0.9', 'Oligodendrocytes': '0.1', 'Microglial cells': '1.8', 'Muller glia cells': '2.4', 'Schwann cells': '0.099', 'Spermatogonia': '0.401', 'Spermatocytes': '-0.062', 'Early spermatids': '-0.578', 'Late spermatids': '-0.618', 'Oocytes': '1.5', 'Cytotrophoblasts': '6.6', 'Syncytiotrophoblasts': '9.8', 'Extravillous trophoblasts': '10.0', 'Endothelial cells': '7.8', 'Lymphatic endothelial cells': '6.9', 'Cardiomyocytes': '0.335', 'Skeletal myocytes': '-0.080', 'Smooth muscle cells': '6.3', 'Adipocytes': '8.3', 'Melanocytes': '0.101', 'Fibroblasts': '6.5', 'Peritubular cells': '0.579', 'Endometrial stromal cells': '4.5', 'Ovarian stromal cells': '6.7', 'Undifferentiated cells': '5.9', 'T-cells': '9.9', 'B-cells': '8.8', 'Plasma cells': '5.0', 'Nk-cells': '15.1', 'Granulocytes': '6.2', 'Monocytes': '7.8', 'Macrophages': '8.5', 'Hofbauer cells': '9.9', 'Kupffer cells': '10.3', 'Dendritic cells': '8.0', 'Langerhans cells': '0.466', 'Erythroid cells': '-0.084', 'Adipocytes (Subcutaneous)': '-0.368', 'Adipocytes (Visceral)': '-0.167', 'Breast glandular cells (progenitors)': '0.190', 'Adipocytes (Breast)': '-0.382', 'Colon enterocytes': '0.004', 'Colon enteroendocrine cells': '0.196', 'Enteric glia cells': '-0.129', 'Mitotic cells (Colon)': '0.005', 'Mitotic cells (Heart)': '0.486', 'Podocytes': '-0.114', 'Ascending Loop of Henle cells': '0.371', 'Intercalated cells': '-0.097', 'Cholangiocyte': '0.375', 'NK-cells (Liver)': '-0.278', 'Respiratory ciliated cells': '-0.022', 'Mitotic cells (Lung)': '0.157', 'NK-cells (Lung)': '0.110', 'B-cells (Lung)': '-0.155', 'Alpha cells': '0.333', 'Beta cells': '0.161', 'Prostate glandular cells': '-0.162', 'Prostate basal glandular cells': '0.286', 'Urothelial cells': '0.283', 'Keratinocyte (other)': '0.121', 'Keratinocyte (granular)': '-0.008', 'Hair cortex cells': '-0.113', 'Inner root sheath cells': '-0.069', 'Outer root sheath cells': '0.125', 'Sebaceous gland cells': '0.110', 'Eccrine sweat gland cells': '0.070', 'Adipocytes (Skin)': '0.019', 'Mitotic cells (Skin)': '0.236', 'Parietal cells': '-0.609', 'Chief cells': '-0.599', 'Gastric mucous cells': '-0.193', 'Gastric enteroendocrine cells': '-0.441', 'Mitotic cells (Stomach)': '0.261', 'Parafollicular cells': '-0.028', 'Thyroid glandular cells': '0.094', 'Mitotic cells (Thyroid)': '0.242', 'Adrenal cortex cells': '0.619', 'Adrenal medulla cells': '0.063', 'Mitotic cells (Adrenal gland)': '0.483', 'Minor salivary glandular cells': '0.582', 'Minor salivary gland ductal cells': '0.072', 'Minor salivary gland basal cells': '0.229', 'Mitotic cells (Minor salivary gland)': '0.376', 'Adipocytes (Minor salivary gland)': '0.211', 'Somatotropes': '-0.121', 'Lactotropes': '-0.287', 'Gonadotropes': '0.004', 'Corticotropes': '-0.352', 'Thyrotropes': '-0.054', 'Undifferentiated cells (Pituitary gland)': '0.486', 'Mitotic cells (Spleen)': '-0.016', 'Platelets': '0.115', 'Erythrocytes': '0.098', 'Hematopoietic stem cells': '0.042', 'B-cells (Spleen)': '0.028', 'NK-cells (Spleen)': '0.157', 'Amygdala excitatory': '0.1', 'Cerebellar inhibitory': '0.2', 'Cge interneuron': '0.3', 'Deep-layer corticothalamic and 6b': '0.3', 'Deep-layer intratelencephalic': '0.1', 'Deep-layer near-projecting': '0.1', 'Eccentric medium spiny neuron': '0.4', 'Hippocampal ca1-3': '0.5', 'Hippocampal ca4': '0.1', 'Hippocampal dentate gyrus': '0.3', 'Lamp5-lhx6 and chandelier': '0.3', 'Lower rhombic lip': '0.2', 'Mammillary body': '0.4', 'Medium spiny neuron': '0.6', 'Mge interneuron': '0.1', 'Midbrain-derived inhibitory': '0.6', 'Miscellaneous': '0.6', 'Splatter': '0.5', 'Thalamic excitatory': '1.3', 'Upper rhombic lip': '0.1', 'Upper-layer intratelencephalic': '0.1', 'Astrocyte': '1.5', 'Bergmann glia': '1.5', 'Central nervous system macrophage': '6.0', 'Choroid plexus epithelial cell': '2.9', 'Committed oligodendrocyte precursor': '1.0', 'Ependymal cell': '1.3', 'Oligodendrocyte': '0.1', 'Oligodendrocyte precursor cell': '2.3', 'Endothelial cell': '6.4', 'Pericyte': '5.3', 'Vascular associated smooth muscle cell': '3.1', 'Fibroblast': '5.3', 'Leukocyte': '7.4', 'Basophil': '107.0', 'Eosinophil': '312.5', 'Neutrophil': '496.9', 'Classical monocyte': '25.8', 'Non-classical monocyte': '66.1', 'Intermediate monocyte': '117.0', 'T-reg': '72.1', 'GdT-cell': '89.5', 'MAIT T-cell': '61.2', 'Memory CD4 T-cell': '76.8', 'Naive CD4 T-cell': '47.0', 'Memory CD8 T-cell': '81.1', 'Naive CD8 T-cell': '43.5', 'Memory B-cell': '50.4', 'Naive B-cell': '38.5', 'Plasmacytoid DC': '47.5', 'Myeloid DC': '92.2', 'NK-cell': '88.9', 'Total PBMC': '83.8', 'Vd2 gdTCR': '67.8', 'Memory CD4 T-cell Th1\\/Th17': '48.0', 'Memory CD4 T-cell Th17': '54.6', 'Memory CD4 T-cell Th2': '54.8', 'Non-Vd2 gdTCR': '73.7', 'Memory CD4 T-cell Th1': '58.8', 'Memory CD4 T-cell TFH': '61.9', 'Terminal effector memory CD4 T-cell': '72.8', 'Central memory CD8 T-cell': '59.9', 'Effector memory CD8 T-cell': '90.7', 'Terminal effector memory CD8 T-cell': '75.8', 'Non-switched memory B-cell': '52.6', 'Plasmablast': '62.3', 'Switched memory B-cell': '55.8', 'Exhausted memory B-cell': '52.1', 'Progenitor cell': '44.7', 'Memory T-reg': '82.4', 'Naive CD4 T-cell activated': '133.9', 'Naive CD8 T-cell activated': '163.4', 'Naive T-reg': '54.7'} | 2IWG, 5JPX, 5OLM, 6FGA, 6S53, 7BBD, 8A58 | {'Adipose Tissue': 21.42795099667774, 'Adrenal Gland': 16.707763565891472, 'Bladder': 21.861904761904764, 'Blood': 61.11958557588805, 'Blood Vessel': 22.62928389513109, 'Brain': 4.305000416351249, 'Breast': 20.001740740740743, 'Cervix Uteri': 26.420526315789473, 'Colon': 23.40817458279846, 'Esophagus': 21.74157577854671, 'Fallopian Tube': 25.39, 'Heart': 6.66628106852497, 'Kidney': 13.61479775280899, 'Liver': 10.388, 'Lung': 32.00464878892734, 'Muscle': 3.944284806973848, 'Nerve': 25.39305008077545, 'Ovary': 30.51811111111111, 'Pancreas': 6.808080182926829, 'Pituitary': 12.995699646643107, 'Prostate': 21.00597551020408, 'Salivary Gland': 16.434148148148147, 'Skin': 17.851811498065228, 'Small Intestine': 28.907085561497325, 'Spleen': 50.16024896265561, 'Stomach': 19.072721448467966, 'Testis': 6.377013850415512, 'Thyroid': 21.553307810107196, 'Uterus': 29.83549295774648, 'Vagina': 21.551141025641027} | IRF8 | MCDRNGGRRLRQWLIEQIDSSMYPGLIWENEEKSMFRIPWKHAGKQDYNQEVDASIFKAWAVFKGKFKEGDKAEPATWKTRLRCALNKSPDFEEVTDRSQLDISEPYKVYRIVPEEEQKCKLGVATAGCVNEVTEMECGRSEIDELIKEPSVDDYMGMIKRSPSPPEACRSQLLPDWWAQQPSTGVPLVTGYTTYDAHHSAFSQMVISFYYGGKLVGQATTTCPEGCRLSLSQPGLPGTKLYGPEGLELVRFPPADAIPSERQRQVTRKLFGHLERGVLLHSSRQGVFVKRLCQGRVFCSGNAVVCKGRPNKLERDEVVQVFDTSQFFRELQQFYNSQGRLPDGRVVLCFGEEFPDMAPLRSKLILVQIEQLYVRQLAEEAGKSCGAGSVMQAPEEPPPDQVFRMFPDICASHQRSFFRENQQITV | Homo sapiens | Nucleus, Cytoplasm | Tissue enhanced (lymphoid) | {'Ciliated cells': '3.8', 'Basal respiratory cells': '0.0', 'Club cells': '3.9', 'Ionocytes': '0.0', 'Mucus glandular cells': '5.9', 'Serous glandular cells': '11.0', 'Gastric mucus-secreting cells': '14.7', 'Proximal enterocytes': '32.2', 'Paneth cells': '13.2', 'Distal enterocytes': '14.1', 'Intestinal goblet cells': '9.4', 'Exocrine glandular cells': '-0.393', 'Basal prostatic cells': '18.3', 'Prostatic glandular cells': '1.2', 'Breast glandular cells': '-0.342', 'Breast myoepithelial cells': '-0.383', 'Glandular and luminal cells': '11.1', 'Secretory cells': '13.0', 'Basal keratinocytes': '3.6', 'Suprabasal keratinocytes': '2.0', 'Basal squamous epithelial cells': '0.7', 'Squamous epithelial cells': '0.3', 'Alveolar cells type 1': '-0.051', 'Alveolar cells type 2': '0.335', 'Salivary duct cells': '0.6', 'Ductal cells': '0.414', 'Hepatocytes': '0.192', 'Cholangiocytes': '3.8', 'Proximal tubular cells': '0.245', 'Distal tubular cells': '3.1', 'Collecting duct cells': '0.0', 'Mesothelial cells': '-0.305', 'Sertoli cells': '0.290', 'Granulosa cells': '2.2', 'Enteroendocrine cells': '19.6', 'Pancreatic endocrine cells': '0.0', 'Leydig cells': '0.438', 'Excitatory neurons': '0.5', 'Inhibitory neurons': '0.2', 'Cone photoreceptor cells': '0.0', 'Rod photoreceptor cells': '0.3', 'Bipolar cells': '0.0', 'Horizontal cells': '0.0', 'Astrocytes': '0.0', 'Oligodendrocyte precursor cells': '0.9', 'Oligodendrocytes': '0.4', 'Microglial cells': '32.2', 'Muller glia cells': '2.6', 'Schwann cells': '0.082', 'Spermatogonia': '0.755', 'Spermatocytes': '0.354', 'Early spermatids': '-0.275', 'Late spermatids': '-0.373', 'Oocytes': '9.6', 'Cytotrophoblasts': '0.6', 'Syncytiotrophoblasts': '0.8', 'Extravillous trophoblasts': '6.1', 'Endothelial cells': '5.4', 'Lymphatic endothelial cells': '37.4', 'Cardiomyocytes': '0.355', 'Skeletal myocytes': '-0.031', 'Smooth muscle cells': '6.0', 'Adipocytes': '3.3', 'Melanocytes': '0.108', 'Fibroblasts': '6.3', 'Peritubular cells': '0.291', 'Endometrial stromal cells': '6.6', 'Ovarian stromal cells': '0.9', 'Undifferentiated cells': '26.9', 'T-cells': '17.8', 'B-cells': '339.6', 'Plasma cells': '10.1', 'Nk-cells': '55.9', 'Granulocytes': '1.9', 'Monocytes': '203.4', 'Macrophages': '128.7', 'Hofbauer cells': '86.3', 'Kupffer cells': '90.7', 'Dendritic cells': '1116.2', 'Langerhans cells': '0.376', 'Erythroid cells': '-0.063', 'Adipocytes (Subcutaneous)': '0.544', 'Adipocytes (Visceral)': '0.659', 'Breast glandular cells (progenitors)': '-0.402', 'Adipocytes (Breast)': '0.735', 'Colon enterocytes': '0.346', 'Colon enteroendocrine cells': '0.115', 'Enteric glia cells': '-0.025', 'Mitotic cells (Colon)': '0.550', 'Mitotic cells (Heart)': '0.593', 'Podocytes': '-0.190', 'Ascending Loop of Henle cells': '0.212', 'Intercalated cells': '-0.212', 'Cholangiocyte': '0.287', 'NK-cells (Liver)': '-0.096', 'Respiratory ciliated cells': '-0.084', 'Mitotic cells (Lung)': '0.168', 'NK-cells (Lung)': '-0.130', 'B-cells (Lung)': '0.099', 'Alpha cells': '0.270', 'Beta cells': '0.108', 'Prostate glandular cells': '-0.086', 'Prostate basal glandular cells': '0.226', 'Urothelial cells': '0.178', 'Keratinocyte (other)': '-0.230', 'Keratinocyte (granular)': '-0.049', 'Hair cortex cells': '0.032', 'Inner root sheath cells': '0.064', 'Outer root sheath cells': '0.124', 'Sebaceous gland cells': '0.135', 'Eccrine sweat gland cells': '0.122', 'Adipocytes (Skin)': '0.275', 'Mitotic cells (Skin)': '-0.004', 'Parietal cells': '0.477', 'Chief cells': '0.392', 'Gastric mucous cells': '0.722', 'Gastric enteroendocrine cells': '0.483', 'Mitotic cells (Stomach)': '0.530', 'Parafollicular cells': '-0.028', 'Thyroid glandular cells': '-0.234', 'Mitotic cells (Thyroid)': '0.438', 'Adrenal cortex cells': '0.437', 'Adrenal medulla cells': '0.069', 'Mitotic cells (Adrenal gland)': '0.352', 'Minor salivary glandular cells': '0.459', 'Minor salivary gland ductal cells': '0.090', 'Minor salivary gland basal cells': '0.208', 'Mitotic cells (Minor salivary gland)': '0.433', 'Adipocytes (Minor salivary gland)': '0.261', 'Somatotropes': '-0.375', 'Lactotropes': '-0.391', 'Gonadotropes': '-0.082', 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0.34, 0.36, 0.11, 0.63, 0.75, 0.52, 0.19, 0.11, 0.55, 0.33, 0.24, 0.52, 0.58, 0.1, 0.18, 0.16, 0.0, 0.02, 0.3, 0.12, 0.01, 0.48, 0.52, 0.82, 0.43, 0.17, 0.78, 0.75, 0.66, 0.81, 0.73, 0.95, 0.93, 0.98, 1.0, 0.99, 1.0, 1.0, 1.0, 0.98, 0.96, 0.94, 0.96, 0.94, 1.0, 0.94, 0.84, 1.0, 0.75, 0.88, 0.86, 0.7, 0.88, 0.82, 0.74, 0.89, 0.95, 0.9, 0.71, 0.92, 0.81, 0.83, 0.8, 0.9, 0.69, 0.95, 0.98, 0.93, 0.94, 0.95, 0.85, 0.9, 0.91, 0.9, 0.96, 0.88, 0.97, 0.92, 0.99, 0.91, 0.96, 0.9, 0.5, 0.66, 0.6, 0.34, 0.6, 0.84, 0.64, 0.87, 0.71, 0.85, 0.84, 0.85, 0.95, 0.83, 0.78, 1.0, 0.94, 0.82, 0.71, 0.98, 0.6, 0.81, 1.0, 0.9, 0.52, 0.57, 0.22, 0.1, 0.1, 0.31, 0.0, 0.05, 0.0, 0.06, 0.01, 0.14, 0.04, 0.23, 0.33, 0.59, 0.53, 0.27, 0.27, 0.62, 0.29, 0.51, 0.0, 0.46, 0.09, 0.59, 0.52, 0.0, 0.0, 0.22, 0.0, 0.01, 0.32, 0.46, 0.9, 0.97, 0.42, 0.79, 0.94, 0.95, 0.59, 0.44, 0.32, 0.61, 0.36, 0.92, 0.54, 0.35, 0.09, 0.08, 0.2, 0.04, 0.35, 0.08, 0.16, 0.63, 0.06, 0.58, 0.54, 0.04, 0.8, 0.44, 0.44, 0.45, 0.12, 0.27, 0.55, 0.22, 0.0, 0.44, 0.59, 0.03, 0.11, 0.47, 0.19, 0.01, 0.71, 0.48, 0.02, 0.01, 0.08, 0.01, 0.12, 0.04, 0.23, 0.75, 0.34, 0.0, 0.01, 0.11, 0.0, 0.09, 0.05, 0.09, 0.0, 0.49, 0.03, 0.04, 0.0, 0.01, 0.04, 0.25, 0.16, 0.08, 0.32, 0.1, 0.92, 0.48, 0.59, 0.91, 0.58, 0.42, 0.15, 0.23, 0.03, 0.3, 0.5, 0.51, 0.53, 0.38, 0.26, 0.34, 0.0, 0.01, 0.27, 0.0, 0.53, 0.2, 0.01, 0.35, 0.59, 0.27, 0.08, 0.47, 0.51, 0.19, 0.6, 0.6, 0.82, 0.77, 0.53, 0.69, 0.4, 0.09, 0.45, 0.14, 0.38, 0.01, 0.17, 0.0, 0.0, 0.01, 0.05, 0.08, 0.15, 0.1, 0.23, 0.47, 0.97, 0.33, 0.53, 0.45, 0.76, 0.19, 0.02, 0.06, 0.0, 0.07, 0.0, 0.14, 0.0, 0.16, 0.02, 0.22, 0.36, 0.02, 0.33, 0.44, 0.19, 0.2, 0.43, 0.58, 0.0, 0.46, 0.67, 0.66, 0.64, 0.59, 0.68, 0.84, 0.82, 0.9, 0.95, 1.0, 1.0, 1.0, 0.96, 1.0, 0.92, 0.92, 0.97, 0.93, 0.96, 0.98, 0.66, 0.87, 0.74, 0.87, 0.93, 0.74, 0.95, 0.96, 1.0, 1.0, 0.94, 1.0, 0.84, 0.93, 0.76, 0.33, 0.81, 0.8, 0.71, 0.49, 0.66, 0.23, 0.32, 0.46] | RING finger | Component of a SCF(SKP2)-like complex containing CUL1, SKP1, TRIM21 and SKP2. | SCF | null | IRF8, CALR, CUL1, FBXW11, HSPA5, IKBKB, IRF3, SKP1 , VCP,SKP2, DCP2 ,ULK1, BECN1,GABARAP, GABARAPL1, GABARAPL2 , MAP1LC3C,SQSTM1,IRF3 , NMI, IFI35 , CUL1, TRIM21 | USP4, IKBKB, TRIM21, CDKN1B, IRF3, IRF8, MNI | mono, 63 | null | UBE2D2, UBE2D1, UBE2E1, UBE2E2 | Homotrimer | null | 90.718042 | 0.406716 | 74.384413 | 0.477042 | 1,865 |
P19474 | Q04206 | 32232831 | UbiNet, UbiBrowser | TRIM21 | MASAARLTMMWEEVTCPICLDPFVEPVSIECGHSFCQECISQVGKGGGSVCPVCRQRFLLKNLRPNRQLANMVNNLKEISQEAREGTQGERCAVHGERLHLFCEKDGKALCWVCAQSRKHRDHAMVPLEEAAQEYQEKLQVALGELRRKQELAEKLEVEIAIKRADWKKTVETQKSRIHAEFVQQKNFLVEEEQRQLQELEKDEREQLRILGEKEAKLAQQSQALQELISELDRRCHSSALELLQEVIIVLERSESWNLKDLDITSPELRSVCHVPGLKKMLRTCAVHITLDPDTANPWLILSEDRRQVRLGDTQQSIPGNEERFDSYPMVLGAQHFHSGKHYWEVDVTGKEAWDLGVCRDSVRRKGHFLLSSKSGFWTIWLWNKQKYEAGTYPQTPLHLQVPPCQVGIFLDYEAGMVSFYNITDHGSLIYSFSECAFTGPLRPFFSPGFNDGGKNTAPLTLCPLNIGSQGSTDY | Homo sapiens | Cytoplasm, Cytoplasmic vesicle, autophagosome, Nucleus, Cytoplasm, P-body, Cytoplasm, Stress granule | Low tissue specificity | {'Ciliated cells': '3.8', 'Basal respiratory cells': '6.8', 'Club cells': '5.8', 'Ionocytes': '3.7', 'Mucus glandular cells': '4.8', 'Serous glandular cells': '2.3', 'Gastric mucus-secreting cells': '8.8', 'Proximal enterocytes': '8.9', 'Paneth cells': '3.9', 'Distal enterocytes': '8.5', 'Intestinal goblet cells': '8.4', 'Exocrine glandular cells': '-0.716', 'Basal prostatic cells': '5.4', 'Prostatic glandular cells': '5.0', 'Breast glandular cells': '0.298', 'Breast myoepithelial cells': '0.351', 'Glandular and luminal cells': '5.9', 'Secretory cells': '8.4', 'Basal keratinocytes': '3.2', 'Suprabasal keratinocytes': '2.7', 'Basal squamous epithelial cells': '6.4', 'Squamous epithelial cells': '4.3', 'Alveolar cells type 1': '0.116', 'Alveolar cells type 2': '0.115', 'Salivary duct cells': '3.0', 'Ductal cells': '0.700', 'Hepatocytes': '0.503', 'Cholangiocytes': '11.4', 'Proximal tubular cells': '0.175', 'Distal tubular cells': '0.0', 'Collecting duct cells': '5.8', 'Mesothelial cells': '0.451', 'Sertoli cells': '0.479', 'Granulosa cells': '4.8', 'Enteroendocrine cells': '3.7', 'Pancreatic endocrine cells': '3.4', 'Leydig cells': '0.632', 'Excitatory neurons': '0.2', 'Inhibitory neurons': '0.1', 'Cone photoreceptor cells': '0.0', 'Rod photoreceptor cells': '0.0', 'Bipolar cells': '0.7', 'Horizontal cells': '0.6', 'Astrocytes': '0.0', 'Oligodendrocyte precursor cells': '0.9', 'Oligodendrocytes': '0.1', 'Microglial cells': '1.8', 'Muller glia cells': '2.4', 'Schwann cells': '0.099', 'Spermatogonia': '0.401', 'Spermatocytes': '-0.062', 'Early spermatids': '-0.578', 'Late spermatids': '-0.618', 'Oocytes': '1.5', 'Cytotrophoblasts': '6.6', 'Syncytiotrophoblasts': '9.8', 'Extravillous trophoblasts': '10.0', 'Endothelial cells': '7.8', 'Lymphatic endothelial cells': '6.9', 'Cardiomyocytes': '0.335', 'Skeletal myocytes': '-0.080', 'Smooth muscle cells': '6.3', 'Adipocytes': '8.3', 'Melanocytes': '0.101', 'Fibroblasts': '6.5', 'Peritubular cells': '0.579', 'Endometrial stromal cells': '4.5', 'Ovarian stromal cells': '6.7', 'Undifferentiated cells': '5.9', 'T-cells': '9.9', 'B-cells': '8.8', 'Plasma cells': '5.0', 'Nk-cells': '15.1', 'Granulocytes': '6.2', 'Monocytes': '7.8', 'Macrophages': '8.5', 'Hofbauer cells': '9.9', 'Kupffer cells': '10.3', 'Dendritic cells': '8.0', 'Langerhans cells': '0.466', 'Erythroid cells': '-0.084', 'Adipocytes (Subcutaneous)': '-0.368', 'Adipocytes (Visceral)': '-0.167', 'Breast glandular cells (progenitors)': '0.190', 'Adipocytes (Breast)': '-0.382', 'Colon enterocytes': '0.004', 'Colon enteroendocrine cells': '0.196', 'Enteric glia cells': '-0.129', 'Mitotic cells (Colon)': '0.005', 'Mitotic cells (Heart)': '0.486', 'Podocytes': '-0.114', 'Ascending Loop of Henle cells': '0.371', 'Intercalated cells': '-0.097', 'Cholangiocyte': '0.375', 'NK-cells (Liver)': '-0.278', 'Respiratory ciliated cells': '-0.022', 'Mitotic cells (Lung)': '0.157', 'NK-cells (Lung)': '0.110', 'B-cells (Lung)': '-0.155', 'Alpha cells': '0.333', 'Beta cells': '0.161', 'Prostate glandular cells': '-0.162', 'Prostate basal glandular cells': '0.286', 'Urothelial cells': '0.283', 'Keratinocyte (other)': '0.121', 'Keratinocyte (granular)': '-0.008', 'Hair cortex cells': '-0.113', 'Inner root sheath cells': '-0.069', 'Outer root sheath cells': '0.125', 'Sebaceous gland cells': '0.110', 'Eccrine sweat gland cells': '0.070', 'Adipocytes (Skin)': '0.019', 'Mitotic cells (Skin)': '0.236', 'Parietal cells': '-0.609', 'Chief cells': '-0.599', 'Gastric mucous cells': '-0.193', 'Gastric enteroendocrine cells': '-0.441', 'Mitotic cells (Stomach)': '0.261', 'Parafollicular cells': '-0.028', 'Thyroid glandular cells': '0.094', 'Mitotic cells (Thyroid)': '0.242', 'Adrenal cortex cells': '0.619', 'Adrenal medulla cells': '0.063', 'Mitotic cells (Adrenal gland)': '0.483', 'Minor salivary glandular cells': '0.582', 'Minor salivary gland ductal cells': '0.072', 'Minor salivary gland basal cells': '0.229', 'Mitotic cells (Minor salivary gland)': '0.376', 'Adipocytes (Minor salivary gland)': '0.211', 'Somatotropes': '-0.121', 'Lactotropes': '-0.287', 'Gonadotropes': '0.004', 'Corticotropes': '-0.352', 'Thyrotropes': '-0.054', 'Undifferentiated cells (Pituitary gland)': '0.486', 'Mitotic cells (Spleen)': '-0.016', 'Platelets': '0.115', 'Erythrocytes': '0.098', 'Hematopoietic stem cells': '0.042', 'B-cells (Spleen)': '0.028', 'NK-cells (Spleen)': '0.157', 'Amygdala excitatory': '0.1', 'Cerebellar inhibitory': '0.2', 'Cge interneuron': '0.3', 'Deep-layer corticothalamic and 6b': '0.3', 'Deep-layer intratelencephalic': '0.1', 'Deep-layer near-projecting': '0.1', 'Eccentric medium spiny neuron': '0.4', 'Hippocampal ca1-3': '0.5', 'Hippocampal ca4': '0.1', 'Hippocampal dentate gyrus': '0.3', 'Lamp5-lhx6 and chandelier': '0.3', 'Lower rhombic lip': '0.2', 'Mammillary body': '0.4', 'Medium spiny neuron': '0.6', 'Mge interneuron': '0.1', 'Midbrain-derived inhibitory': '0.6', 'Miscellaneous': '0.6', 'Splatter': '0.5', 'Thalamic excitatory': '1.3', 'Upper rhombic lip': '0.1', 'Upper-layer intratelencephalic': '0.1', 'Astrocyte': '1.5', 'Bergmann glia': '1.5', 'Central nervous system macrophage': '6.0', 'Choroid plexus epithelial cell': '2.9', 'Committed oligodendrocyte precursor': '1.0', 'Ependymal cell': '1.3', 'Oligodendrocyte': '0.1', 'Oligodendrocyte precursor cell': '2.3', 'Endothelial cell': '6.4', 'Pericyte': '5.3', 'Vascular associated smooth muscle cell': '3.1', 'Fibroblast': '5.3', 'Leukocyte': '7.4', 'Basophil': '107.0', 'Eosinophil': '312.5', 'Neutrophil': '496.9', 'Classical monocyte': '25.8', 'Non-classical monocyte': '66.1', 'Intermediate monocyte': '117.0', 'T-reg': '72.1', 'GdT-cell': '89.5', 'MAIT T-cell': '61.2', 'Memory CD4 T-cell': '76.8', 'Naive CD4 T-cell': '47.0', 'Memory CD8 T-cell': '81.1', 'Naive CD8 T-cell': '43.5', 'Memory B-cell': '50.4', 'Naive B-cell': '38.5', 'Plasmacytoid DC': '47.5', 'Myeloid DC': '92.2', 'NK-cell': '88.9', 'Total PBMC': '83.8', 'Vd2 gdTCR': '67.8', 'Memory CD4 T-cell Th1\\/Th17': '48.0', 'Memory CD4 T-cell Th17': '54.6', 'Memory CD4 T-cell Th2': '54.8', 'Non-Vd2 gdTCR': '73.7', 'Memory CD4 T-cell Th1': '58.8', 'Memory CD4 T-cell TFH': '61.9', 'Terminal effector memory CD4 T-cell': '72.8', 'Central memory CD8 T-cell': '59.9', 'Effector memory CD8 T-cell': '90.7', 'Terminal effector memory CD8 T-cell': '75.8', 'Non-switched memory B-cell': '52.6', 'Plasmablast': '62.3', 'Switched memory B-cell': '55.8', 'Exhausted memory B-cell': '52.1', 'Progenitor cell': '44.7', 'Memory T-reg': '82.4', 'Naive CD4 T-cell activated': '133.9', 'Naive CD8 T-cell activated': '163.4', 'Naive T-reg': '54.7'} | 2IWG, 5JPX, 5OLM, 6FGA, 6S53, 7BBD, 8A58 | {'Adipose Tissue': 21.42795099667774, 'Adrenal Gland': 16.707763565891472, 'Bladder': 21.861904761904764, 'Blood': 61.11958557588805, 'Blood Vessel': 22.62928389513109, 'Brain': 4.305000416351249, 'Breast': 20.001740740740743, 'Cervix Uteri': 26.420526315789473, 'Colon': 23.40817458279846, 'Esophagus': 21.74157577854671, 'Fallopian Tube': 25.39, 'Heart': 6.66628106852497, 'Kidney': 13.61479775280899, 'Liver': 10.388, 'Lung': 32.00464878892734, 'Muscle': 3.944284806973848, 'Nerve': 25.39305008077545, 'Ovary': 30.51811111111111, 'Pancreas': 6.808080182926829, 'Pituitary': 12.995699646643107, 'Prostate': 21.00597551020408, 'Salivary Gland': 16.434148148148147, 'Skin': 17.851811498065228, 'Small Intestine': 28.907085561497325, 'Spleen': 50.16024896265561, 'Stomach': 19.072721448467966, 'Testis': 6.377013850415512, 'Thyroid': 21.553307810107196, 'Uterus': 29.83549295774648, 'Vagina': 21.551141025641027} | RELA | MDELFPLIFPAEPAQASGPYVEIIEQPKQRGMRFRYKCEGRSAGSIPGERSTDTTKTHPTIKINGYTGPGTVRISLVTKDPPHRPHPHELVGKDCRDGFYEAELCPDRCIHSFQNLGIQCVKKRDLEQAISQRIQTNNNPFQVPIEEQRGDYDLNAVRLCFQVTVRDPSGRPLRLPPVLSHPIFDNRAPNTAELKICRVNRNSGSCLGGDEIFLLCDKVQKEDIEVYFTGPGWEARGSFSQADVHRQVAIVFRTPPYADPSLQAPVRVSMQLRRPSDRELSEPMEFQYLPDTDDRHRIEEKRKRTYETFKSIMKKSPFSGPTDPRPPPRRIAVPSRSSASVPKPAPQPYPFTSSLSTINYDEFPTMVFPSGQISQASALAPAPPQVLPQAPAPAPAPAMVSALAQAPAPVPVLAPGPPQAVAPPAPKPTQAGEGTLSEALLQLQFDDEDLGALLGNSTDPAVFTDLASVDNSEFQQLLNQGIPVAPHTTEPMLMEYPEAITRLVTGAQRPPDPAPAPLGAPGLPNGLLSGDEDFSSIADMDFSALLSQISS | Homo sapiens | Nucleus, Cytoplasm | Low tissue specificity | {'Ciliated cells': '27.8', 'Basal respiratory cells': '36.3', 'Club cells': '30.6', 'Ionocytes': '35.0', 'Mucus glandular cells': '30.0', 'Serous glandular cells': '18.6', 'Gastric mucus-secreting cells': '27.7', 'Proximal enterocytes': '21.6', 'Paneth cells': '22.1', 'Distal enterocytes': '25.2', 'Intestinal goblet cells': '28.0', 'Exocrine glandular cells': '-0.781', 'Basal prostatic cells': '32.0', 'Prostatic glandular cells': '21.8', 'Breast glandular cells': '0.480', 'Breast myoepithelial cells': '0.511', 'Glandular and luminal cells': '48.1', 'Secretory cells': '56.4', 'Basal keratinocytes': '41.7', 'Suprabasal keratinocytes': '42.7', 'Basal squamous epithelial cells': '27.5', 'Squamous epithelial cells': '28.7', 'Alveolar cells type 1': '0.274', 'Alveolar cells type 2': '-0.452', 'Salivary duct cells': '26.7', 'Ductal cells': '0.612', 'Hepatocytes': '0.191', 'Cholangiocytes': '15.3', 'Proximal tubular cells': '0.114', 'Distal tubular cells': '27.7', 'Collecting duct cells': '13.6', 'Mesothelial cells': '0.281', 'Sertoli cells': '0.582', 'Granulosa cells': '26.4', 'Enteroendocrine cells': '19.9', 'Pancreatic endocrine cells': '34.0', 'Leydig cells': '0.608', 'Excitatory neurons': '5.3', 'Inhibitory neurons': '5.7', 'Cone photoreceptor cells': '3.4', 'Rod photoreceptor cells': '8.0', 'Bipolar cells': '7.7', 'Horizontal cells': '7.6', 'Astrocytes': '8.7', 'Oligodendrocyte precursor cells': '7.1', 'Oligodendrocytes': '12.8', 'Microglial cells': '9.8', 'Muller glia cells': '16.3', 'Schwann cells': '0.049', 'Spermatogonia': '0.500', 'Spermatocytes': '0.061', 'Early spermatids': '-0.521', 'Late spermatids': '-0.641', 'Oocytes': '19.9', 'Cytotrophoblasts': '23.0', 'Syncytiotrophoblasts': '47.7', 'Extravillous trophoblasts': '27.7', 'Endothelial cells': '45.2', 'Lymphatic endothelial cells': '33.2', 'Cardiomyocytes': '0.352', 'Skeletal myocytes': '-0.285', 'Smooth muscle cells': '35.1', 'Adipocytes': '41.0', 'Melanocytes': '0.007', 'Fibroblasts': '29.1', 'Peritubular cells': '0.494', 'Endometrial stromal cells': '24.8', 'Ovarian stromal cells': '26.5', 'Undifferentiated cells': '22.1', 'T-cells': '38.6', 'B-cells': '31.6', 'Plasma cells': '31.3', 'Nk-cells': '37.6', 'Granulocytes': '50.3', 'Monocytes': '61.6', 'Macrophages': '31.1', 'Hofbauer cells': '29.0', 'Kupffer cells': '32.0', 'Dendritic cells': '33.9', 'Langerhans cells': '0.058', 'Erythroid cells': '0.030', 'Adipocytes (Subcutaneous)': '-0.433', 'Adipocytes (Visceral)': '-0.372', 'Breast glandular cells (progenitors)': '0.381', 'Adipocytes (Breast)': '-0.610', 'Colon enterocytes': '-0.207', 'Colon enteroendocrine cells': '0.122', 'Enteric glia cells': '-0.070', 'Mitotic cells (Colon)': '-0.100', 'Mitotic cells (Heart)': '0.438', 'Podocytes': '-0.076', 'Ascending Loop of Henle cells': '0.300', 'Intercalated cells': '-0.112', 'Cholangiocyte': '0.350', 'NK-cells (Liver)': '-0.205', 'Respiratory ciliated cells': '0.037', 'Mitotic cells (Lung)': '-0.355', 'NK-cells (Lung)': '0.499', 'B-cells (Lung)': '0.230', 'Alpha cells': '0.329', 'Beta cells': '0.166', 'Prostate glandular cells': '-0.250', 'Prostate basal glandular cells': '0.085', 'Urothelial cells': '0.227', 'Keratinocyte (other)': '0.166', 'Keratinocyte (granular)': '0.146', 'Hair cortex cells': '-0.085', 'Inner root sheath cells': '-0.061', 'Outer root sheath cells': '-0.109', 'Sebaceous gland cells': '-0.251', 'Eccrine sweat gland cells': '-0.128', 'Adipocytes (Skin)': '-0.097', 'Mitotic cells (Skin)': '-0.171', 'Parietal cells': '-0.714', 'Chief cells': '-0.564', 'Gastric mucous cells': '-0.402', 'Gastric enteroendocrine cells': '-0.424', 'Mitotic cells (Stomach)': '-0.035', 'Parafollicular cells': '0.023', 'Thyroid glandular cells': '-0.011', 'Mitotic cells (Thyroid)': '0.012', 'Adrenal cortex cells': '0.387', 'Adrenal medulla cells': '0.016', 'Mitotic cells (Adrenal gland)': '0.000', 'Minor salivary glandular cells': '0.624', 'Minor salivary gland ductal cells': '-0.001', 'Minor salivary gland basal cells': '0.331', 'Mitotic cells (Minor salivary gland)': '0.331', 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0.98, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 0.92, 1.0, 0.91, 0.99, 1.0, 1.0, 0.95, 0.99, 0.91, 0.85, 0.92, 0.85, 0.73, 0.9, 0.96, 0.78, 0.85, 0.93, 0.91, 0.85] | RING finger | Component of a SCF(SKP2)-like complex containing CUL1, SKP1, TRIM21 and SKP2. | SCF | null | IRF8, CALR, CUL1, FBXW11, HSPA5, IKBKB, IRF3, SKP1 , VCP,SKP2, DCP2 ,ULK1, BECN1,GABARAP, GABARAPL1, GABARAPL2 , MAP1LC3C,SQSTM1,IRF3 , NMI, IFI35 , CUL1, TRIM21 | USP4, IKBKB, TRIM21, CDKN1B, IRF3, IRF8, MNI | mono, 63 | null | UBE2D2, UBE2D1, UBE2E1, UBE2E2 | Homotrimer | null | 90.718042 | 0.406716 | 72.121615 | 0.605844 | 1,208 |
P19474 | Q13107 | 16472766, BioGrid E3Net | UbiNet, UbiBrowser, 31181401 | TRIM21 | MASAARLTMMWEEVTCPICLDPFVEPVSIECGHSFCQECISQVGKGGGSVCPVCRQRFLLKNLRPNRQLANMVNNLKEISQEAREGTQGERCAVHGERLHLFCEKDGKALCWVCAQSRKHRDHAMVPLEEAAQEYQEKLQVALGELRRKQELAEKLEVEIAIKRADWKKTVETQKSRIHAEFVQQKNFLVEEEQRQLQELEKDEREQLRILGEKEAKLAQQSQALQELISELDRRCHSSALELLQEVIIVLERSESWNLKDLDITSPELRSVCHVPGLKKMLRTCAVHITLDPDTANPWLILSEDRRQVRLGDTQQSIPGNEERFDSYPMVLGAQHFHSGKHYWEVDVTGKEAWDLGVCRDSVRRKGHFLLSSKSGFWTIWLWNKQKYEAGTYPQTPLHLQVPPCQVGIFLDYEAGMVSFYNITDHGSLIYSFSECAFTGPLRPFFSPGFNDGGKNTAPLTLCPLNIGSQGSTDY | Homo sapiens | Cytoplasm, Cytoplasmic vesicle, autophagosome, Nucleus, Cytoplasm, P-body, Cytoplasm, Stress granule | Low tissue specificity | {'Ciliated cells': '3.8', 'Basal respiratory cells': '6.8', 'Club cells': '5.8', 'Ionocytes': '3.7', 'Mucus glandular cells': '4.8', 'Serous glandular cells': '2.3', 'Gastric mucus-secreting cells': '8.8', 'Proximal enterocytes': '8.9', 'Paneth cells': '3.9', 'Distal enterocytes': '8.5', 'Intestinal goblet cells': '8.4', 'Exocrine glandular cells': '-0.716', 'Basal prostatic cells': '5.4', 'Prostatic glandular cells': '5.0', 'Breast glandular cells': '0.298', 'Breast myoepithelial cells': '0.351', 'Glandular and luminal cells': '5.9', 'Secretory cells': '8.4', 'Basal keratinocytes': '3.2', 'Suprabasal keratinocytes': '2.7', 'Basal squamous epithelial cells': '6.4', 'Squamous epithelial cells': '4.3', 'Alveolar cells type 1': '0.116', 'Alveolar cells type 2': '0.115', 'Salivary duct cells': '3.0', 'Ductal cells': '0.700', 'Hepatocytes': '0.503', 'Cholangiocytes': '11.4', 'Proximal tubular cells': '0.175', 'Distal tubular cells': '0.0', 'Collecting duct cells': '5.8', 'Mesothelial cells': '0.451', 'Sertoli cells': '0.479', 'Granulosa cells': '4.8', 'Enteroendocrine cells': '3.7', 'Pancreatic endocrine cells': '3.4', 'Leydig cells': '0.632', 'Excitatory neurons': '0.2', 'Inhibitory neurons': '0.1', 'Cone photoreceptor cells': '0.0', 'Rod photoreceptor cells': '0.0', 'Bipolar cells': '0.7', 'Horizontal cells': '0.6', 'Astrocytes': '0.0', 'Oligodendrocyte precursor cells': '0.9', 'Oligodendrocytes': '0.1', 'Microglial cells': '1.8', 'Muller glia cells': '2.4', 'Schwann cells': '0.099', 'Spermatogonia': '0.401', 'Spermatocytes': '-0.062', 'Early spermatids': '-0.578', 'Late spermatids': '-0.618', 'Oocytes': '1.5', 'Cytotrophoblasts': '6.6', 'Syncytiotrophoblasts': '9.8', 'Extravillous trophoblasts': '10.0', 'Endothelial cells': '7.8', 'Lymphatic endothelial cells': '6.9', 'Cardiomyocytes': '0.335', 'Skeletal myocytes': '-0.080', 'Smooth muscle cells': '6.3', 'Adipocytes': '8.3', 'Melanocytes': '0.101', 'Fibroblasts': '6.5', 'Peritubular cells': '0.579', 'Endometrial stromal cells': '4.5', 'Ovarian stromal cells': '6.7', 'Undifferentiated cells': '5.9', 'T-cells': '9.9', 'B-cells': '8.8', 'Plasma cells': '5.0', 'Nk-cells': '15.1', 'Granulocytes': '6.2', 'Monocytes': '7.8', 'Macrophages': '8.5', 'Hofbauer cells': '9.9', 'Kupffer cells': '10.3', 'Dendritic cells': '8.0', 'Langerhans cells': '0.466', 'Erythroid cells': '-0.084', 'Adipocytes (Subcutaneous)': '-0.368', 'Adipocytes (Visceral)': '-0.167', 'Breast glandular cells (progenitors)': '0.190', 'Adipocytes (Breast)': '-0.382', 'Colon enterocytes': '0.004', 'Colon enteroendocrine cells': '0.196', 'Enteric glia cells': '-0.129', 'Mitotic cells (Colon)': '0.005', 'Mitotic cells (Heart)': '0.486', 'Podocytes': '-0.114', 'Ascending Loop of Henle cells': '0.371', 'Intercalated cells': '-0.097', 'Cholangiocyte': '0.375', 'NK-cells (Liver)': '-0.278', 'Respiratory ciliated cells': '-0.022', 'Mitotic cells (Lung)': '0.157', 'NK-cells (Lung)': '0.110', 'B-cells (Lung)': '-0.155', 'Alpha cells': '0.333', 'Beta cells': '0.161', 'Prostate glandular cells': '-0.162', 'Prostate basal glandular cells': '0.286', 'Urothelial cells': '0.283', 'Keratinocyte (other)': '0.121', 'Keratinocyte (granular)': '-0.008', 'Hair cortex cells': '-0.113', 'Inner root sheath cells': '-0.069', 'Outer root sheath cells': '0.125', 'Sebaceous gland cells': '0.110', 'Eccrine sweat gland cells': '0.070', 'Adipocytes (Skin)': '0.019', 'Mitotic cells (Skin)': '0.236', 'Parietal cells': '-0.609', 'Chief cells': '-0.599', 'Gastric mucous cells': '-0.193', 'Gastric enteroendocrine cells': '-0.441', 'Mitotic cells (Stomach)': '0.261', 'Parafollicular cells': '-0.028', 'Thyroid glandular cells': '0.094', 'Mitotic cells (Thyroid)': '0.242', 'Adrenal cortex cells': '0.619', 'Adrenal medulla cells': '0.063', 'Mitotic cells (Adrenal gland)': '0.483', 'Minor salivary glandular cells': '0.582', 'Minor salivary gland ductal cells': '0.072', 'Minor salivary gland basal cells': '0.229', 'Mitotic cells (Minor salivary gland)': '0.376', 'Adipocytes (Minor salivary gland)': '0.211', 'Somatotropes': '-0.121', 'Lactotropes': '-0.287', 'Gonadotropes': '0.004', 'Corticotropes': '-0.352', 'Thyrotropes': '-0.054', 'Undifferentiated cells (Pituitary gland)': '0.486', 'Mitotic cells (Spleen)': '-0.016', 'Platelets': '0.115', 'Erythrocytes': '0.098', 'Hematopoietic stem cells': '0.042', 'B-cells (Spleen)': '0.028', 'NK-cells (Spleen)': '0.157', 'Amygdala excitatory': '0.1', 'Cerebellar inhibitory': '0.2', 'Cge interneuron': '0.3', 'Deep-layer corticothalamic and 6b': '0.3', 'Deep-layer intratelencephalic': '0.1', 'Deep-layer near-projecting': '0.1', 'Eccentric medium spiny neuron': '0.4', 'Hippocampal ca1-3': '0.5', 'Hippocampal ca4': '0.1', 'Hippocampal dentate gyrus': '0.3', 'Lamp5-lhx6 and chandelier': '0.3', 'Lower rhombic lip': '0.2', 'Mammillary body': '0.4', 'Medium spiny neuron': '0.6', 'Mge interneuron': '0.1', 'Midbrain-derived inhibitory': '0.6', 'Miscellaneous': '0.6', 'Splatter': '0.5', 'Thalamic excitatory': '1.3', 'Upper rhombic lip': '0.1', 'Upper-layer intratelencephalic': '0.1', 'Astrocyte': '1.5', 'Bergmann glia': '1.5', 'Central nervous system macrophage': '6.0', 'Choroid plexus epithelial cell': '2.9', 'Committed oligodendrocyte precursor': '1.0', 'Ependymal cell': '1.3', 'Oligodendrocyte': '0.1', 'Oligodendrocyte precursor cell': '2.3', 'Endothelial cell': '6.4', 'Pericyte': '5.3', 'Vascular associated smooth muscle cell': '3.1', 'Fibroblast': '5.3', 'Leukocyte': '7.4', 'Basophil': '107.0', 'Eosinophil': '312.5', 'Neutrophil': '496.9', 'Classical monocyte': '25.8', 'Non-classical monocyte': '66.1', 'Intermediate monocyte': '117.0', 'T-reg': '72.1', 'GdT-cell': '89.5', 'MAIT T-cell': '61.2', 'Memory CD4 T-cell': '76.8', 'Naive CD4 T-cell': '47.0', 'Memory CD8 T-cell': '81.1', 'Naive CD8 T-cell': '43.5', 'Memory B-cell': '50.4', 'Naive B-cell': '38.5', 'Plasmacytoid DC': '47.5', 'Myeloid DC': '92.2', 'NK-cell': '88.9', 'Total PBMC': '83.8', 'Vd2 gdTCR': '67.8', 'Memory CD4 T-cell Th1\\/Th17': '48.0', 'Memory CD4 T-cell Th17': '54.6', 'Memory CD4 T-cell Th2': '54.8', 'Non-Vd2 gdTCR': '73.7', 'Memory CD4 T-cell Th1': '58.8', 'Memory CD4 T-cell TFH': '61.9', 'Terminal effector memory CD4 T-cell': '72.8', 'Central memory CD8 T-cell': '59.9', 'Effector memory CD8 T-cell': '90.7', 'Terminal effector memory CD8 T-cell': '75.8', 'Non-switched memory B-cell': '52.6', 'Plasmablast': '62.3', 'Switched memory B-cell': '55.8', 'Exhausted memory B-cell': '52.1', 'Progenitor cell': '44.7', 'Memory T-reg': '82.4', 'Naive CD4 T-cell activated': '133.9', 'Naive CD8 T-cell activated': '163.4', 'Naive T-reg': '54.7'} | 2IWG, 5JPX, 5OLM, 6FGA, 6S53, 7BBD, 8A58 | {'Adipose Tissue': 21.42795099667774, 'Adrenal Gland': 16.707763565891472, 'Bladder': 21.861904761904764, 'Blood': 61.11958557588805, 'Blood Vessel': 22.62928389513109, 'Brain': 4.305000416351249, 'Breast': 20.001740740740743, 'Cervix Uteri': 26.420526315789473, 'Colon': 23.40817458279846, 'Esophagus': 21.74157577854671, 'Fallopian Tube': 25.39, 'Heart': 6.66628106852497, 'Kidney': 13.61479775280899, 'Liver': 10.388, 'Lung': 32.00464878892734, 'Muscle': 3.944284806973848, 'Nerve': 25.39305008077545, 'Ovary': 30.51811111111111, 'Pancreas': 6.808080182926829, 'Pituitary': 12.995699646643107, 'Prostate': 21.00597551020408, 'Salivary Gland': 16.434148148148147, 'Skin': 17.851811498065228, 'Small Intestine': 28.907085561497325, 'Spleen': 50.16024896265561, 'Stomach': 19.072721448467966, 'Testis': 6.377013850415512, 'Thyroid': 21.553307810107196, 'Uterus': 29.83549295774648, 'Vagina': 21.551141025641027} | USP4 | MAEGGGCRERPDAETQKSELGPLMRTTLQRGAQWYLIDSRWFKQWKKYVGFDSWDMYNVGEHNLFPGPIDNSGLFSDPESQTLKEHLIDELDYVLVPTEAWNKLLNWYGCVEGQQPIVRKVVEHGLFVKHCKVEVYLLELKLCENSDPTNVLSCHFSKADTIATIEKEMRKLFNIPAERETRLWNKYMSNTYEQLSKLDNTVQDAGLYQGQVLVIEPQNEDGTWPRQTLQSKSSTAPSRNFTTSPKSSASPYSSVSASLIANGDSTSTCGMHSSGVSRGGSGFSASYNCQEPPSSHIQPGLCGLGNLGNTCFMNSALQCLSNTAPLTDYFLKDEYEAEINRDNPLGMKGEIAEAYAELIKQMWSGRDAHVAPRMFKTQVGRFAPQFSGYQQQDSQELLAFLLDGLHEDLNRVKKKPYLELKDANGRPDAVVAKEAWENHRLRNDSVIVDTFHGLFKSTLVCPECAKVSVTFDPFCYLTLPLPLKKDRVMEVFLVPADPHCRPTQYRVTVPLMGAVSDLCEALSRLSGIAAENMVVADVYNHRFHKIFQMDEGLNHIMPRDDIFVYEVCSTSVDGSECVTLPVYFRERKSRPSSTSSASALYGQPLLLSVPKHKLTLESLYQAVCDRISRYVKQPLPDEFGSSPLEPGACNGSRNSCEGEDEEEMEHQEEGKEQLSETEGSGEDEPGNDPSETTQKKIKGQPCPKRLFTFSLVNSYGTADINSLAADGKLLKLNSRSTLAMDWDSETRRLYYDEQESEAYEKHVSMLQPQKKKKTTVALRDCIELFTTMETLGEHDPWYCPNCKKHQQATKKFDLWSLPKILVVHLKRFSYNRYWRDKLDTVVEFPIRGLNMSEFVCNLSARPYVYDLIAVSNHYGAMGVGHYTAYAKNKLNGKWYYFDDSNVSLASEDQIVTKAAYVLFYQRRDDEFYKTPSLSSSGSSDGGTRPSSSQQGFGDDEACSMDTN | Homo sapiens | Cytoplasm, Nucleus | Low tissue specificity | {'Ciliated cells': '22.2', 'Basal respiratory cells': '19.0', 'Club cells': '21.5', 'Ionocytes': '15.5', 'Mucus glandular cells': '27.7', 'Serous glandular cells': '24.1', 'Gastric mucus-secreting cells': '21.8', 'Proximal enterocytes': '15.5', 'Paneth cells': '16.5', 'Distal enterocytes': '14.6', 'Intestinal goblet cells': '19.6', 'Exocrine glandular cells': '-0.777', 'Basal prostatic cells': '20.3', 'Prostatic glandular cells': '19.7', 'Breast glandular cells': '0.445', 'Breast myoepithelial cells': '0.386', 'Glandular and luminal cells': '21.9', 'Secretory cells': '13.1', 'Basal keratinocytes': '22.0', 'Suprabasal keratinocytes': '30.9', 'Basal squamous epithelial cells': '18.6', 'Squamous epithelial cells': '17.3', 'Alveolar cells type 1': '0.079', 'Alveolar cells type 2': '-0.458', 'Salivary duct cells': '23.5', 'Ductal cells': '0.680', 'Hepatocytes': '0.413', 'Cholangiocytes': '13.4', 'Proximal tubular cells': '0.166', 'Distal tubular cells': '18.4', 'Collecting duct cells': '33.1', 'Mesothelial cells': '0.316', 'Sertoli cells': '0.003', 'Granulosa cells': '23.2', 'Enteroendocrine cells': '12.4', 'Pancreatic endocrine cells': '18.7', 'Leydig cells': '-0.141', 'Excitatory neurons': '29.8', 'Inhibitory neurons': '25.3', 'Cone photoreceptor cells': '23.8', 'Rod photoreceptor cells': '22.6', 'Bipolar cells': '20.0', 'Horizontal cells': '17.0', 'Astrocytes': '26.6', 'Oligodendrocyte precursor cells': '24.1', 'Oligodendrocytes': '18.8', 'Microglial cells': '16.1', 'Muller glia cells': '15.7', 'Schwann cells': '0.135', 'Spermatogonia': '0.068', 'Spermatocytes': '0.276', 'Early spermatids': '0.579', 'Late spermatids': '0.283', 'Oocytes': '27.2', 'Cytotrophoblasts': '25.4', 'Syncytiotrophoblasts': '29.0', 'Extravillous trophoblasts': '16.5', 'Endothelial cells': '24.1', 'Lymphatic endothelial cells': '17.0', 'Cardiomyocytes': '0.611', 'Skeletal myocytes': '-0.041', 'Smooth muscle cells': '20.3', 'Adipocytes': '25.7', 'Melanocytes': '0.240', 'Fibroblasts': '18.6', 'Peritubular cells': '0.020', 'Endometrial stromal cells': '18.4', 'Ovarian stromal cells': '16.9', 'Undifferentiated cells': '14.1', 'T-cells': '30.4', 'B-cells': '27.8', 'Plasma cells': '27.3', 'Nk-cells': '31.1', 'Granulocytes': '22.7', 'Monocytes': '46.6', 'Macrophages': '41.3', 'Hofbauer cells': '30.9', 'Kupffer cells': '42.5', 'Dendritic cells': '45.8', 'Langerhans cells': '0.386', 'Erythroid cells': '0.034', 'Adipocytes (Subcutaneous)': '-0.030', 'Adipocytes (Visceral)': '-0.320', 'Breast glandular cells (progenitors)': '0.274', 'Adipocytes (Breast)': '-0.321', 'Colon enterocytes': '-0.277', 'Colon enteroendocrine cells': '0.297', 'Enteric glia cells': '0.468', 'Mitotic cells (Colon)': '-0.153', 'Mitotic cells (Heart)': '0.501', 'Podocytes': '-0.032', 'Ascending Loop of Henle cells': '0.438', 'Intercalated cells': '0.031', 'Cholangiocyte': '0.370', 'NK-cells (Liver)': '-0.239', 'Respiratory ciliated cells': '0.152', 'Mitotic cells (Lung)': '-0.098', 'NK-cells (Lung)': '0.479', 'B-cells (Lung)': '0.181', 'Alpha cells': '0.401', 'Beta cells': '0.232', 'Prostate glandular cells': '-0.120', 'Prostate basal glandular cells': '0.176', 'Urothelial cells': '0.127', 'Keratinocyte (other)': '0.529', 'Keratinocyte (granular)': '0.081', 'Hair cortex cells': '-0.151', 'Inner root sheath cells': '-0.079', 'Outer root sheath cells': '0.041', 'Sebaceous gland cells': '-0.034', 'Eccrine sweat gland cells': '-0.244', 'Adipocytes (Skin)': '-0.328', 'Mitotic cells (Skin)': '0.377', 'Parietal cells': '-0.683', 'Chief cells': '-0.632', 'Gastric mucous cells': '-0.391', 'Gastric enteroendocrine cells': '-0.445', 'Mitotic cells (Stomach)': '0.021', 'Parafollicular cells': '0.060', 'Thyroid glandular cells': '0.223', 'Mitotic cells (Thyroid)': '0.143', 'Adrenal cortex cells': '0.277', 'Adrenal medulla cells': '-0.011', 'Mitotic cells (Adrenal gland)': '0.178', 'Minor salivary glandular cells': '0.453', 'Minor salivary gland ductal cells': '-0.021', 'Minor salivary gland basal cells': '0.579', 'Mitotic cells (Minor salivary gland)': '0.632', 'Adipocytes (Minor salivary gland)': '0.231', 'Somatotropes': '-0.157', 'Lactotropes': '-0.262', 'Gonadotropes': '0.090', 'Corticotropes': '-0.337', 'Thyrotropes': '-0.124', 'Undifferentiated cells (Pituitary gland)': '0.477', 'Mitotic cells (Spleen)': '-0.292', 'Platelets': '-0.165', 'Erythrocytes': '-0.030', 'Hematopoietic stem cells': '-0.322', 'B-cells (Spleen)': '0.388', 'NK-cells (Spleen)': '0.456', 'Amygdala excitatory': '57.3', 'Cerebellar inhibitory': '47.5', 'Cge interneuron': '49.6', 'Deep-layer corticothalamic and 6b': '47.2', 'Deep-layer intratelencephalic': '56.9', 'Deep-layer near-projecting': '55.3', 'Eccentric medium spiny neuron': '61.9', 'Hippocampal ca1-3': '48.3', 'Hippocampal ca4': '44.6', 'Hippocampal dentate gyrus': '69.2', 'Lamp5-lhx6 and chandelier': '50.8', 'Lower rhombic lip': '53.2', 'Mammillary body': '45.3', 'Medium spiny neuron': '80.2', 'Mge interneuron': '55.2', 'Midbrain-derived inhibitory': '44.1', 'Miscellaneous': '55.1', 'Splatter': '44.2', 'Thalamic excitatory': '45.5', 'Upper rhombic lip': '44.6', 'Upper-layer intratelencephalic': '63.9', 'Astrocyte': '57.4', 'Bergmann glia': '32.4', 'Central nervous system macrophage': '136.5', 'Choroid plexus epithelial cell': '67.9', 'Committed oligodendrocyte precursor': '50.4', 'Ependymal cell': '53.2', 'Oligodendrocyte': '44.5', 'Oligodendrocyte precursor cell': '46.5', 'Endothelial cell': '65.6', 'Pericyte': '59.9', 'Vascular associated smooth muscle cell': '50.8', 'Fibroblast': '50.6', 'Leukocyte': '83.9', 'Basophil': '169.6', 'Eosinophil': '95.1', 'Neutrophil': '463.2', 'Classical monocyte': '114.8', 'Non-classical monocyte': '127.0', 'Intermediate monocyte': '150.5', 'T-reg': '107.0', 'GdT-cell': '48.3', 'MAIT T-cell': '118.4', 'Memory CD4 T-cell': '50.4', 'Naive CD4 T-cell': '100.4', 'Memory CD8 T-cell': '49.0', 'Naive CD8 T-cell': '84.8', 'Memory B-cell': '51.2', 'Naive B-cell': '86.6', 'Plasmacytoid DC': '117.7', 'Myeloid DC': '134.5', 'NK-cell': '95.4', 'Total PBMC': '119.8', 'Vd2 gdTCR': '118.2', 'Memory CD4 T-cell Th1\\/Th17': '89.9', 'Memory CD4 T-cell Th17': '99.6', 'Memory CD4 T-cell Th2': '100.4', 'Non-Vd2 gdTCR': '114.7', 'Memory CD4 T-cell Th1': '92.0', 'Memory CD4 T-cell TFH': '98.9', 'Terminal effector memory CD4 T-cell': '102.1', 'Central memory CD8 T-cell': '104.3', 'Effector memory CD8 T-cell': '123.0', 'Terminal effector memory CD8 T-cell': '109.1', 'Non-switched memory B-cell': '109.2', 'Plasmablast': '92.4', 'Switched memory B-cell': '87.4', 'Exhausted memory B-cell': '100.4', 'Progenitor cell': '88.5', 'Memory T-reg': '96.0', 'Naive CD4 T-cell activated': '94.5', 'Naive CD8 T-cell activated': '91.1', 'Naive T-reg': '80.6'} | 2Y6E, 5CTR | {'Adipose Tissue': 27.898247508305648, 'Adrenal Gland': 17.445631782945735, 'Bladder': 31.25142857142857, 'Blood': 39.43077502691066, 'Blood Vessel': 33.27881647940075, 'Brain': 18.700019682059047, 'Breast': 28.6102614379085, 'Cervix Uteri': 37.11157894736842, 'Colon': 24.936695763799744, 'Esophagus': 27.178320415224917, 'Fallopian Tube': 32.291111111111114, 'Heart': 12.57390824622532, 'Kidney': 15.054606741573032, 'Liver': 8.924190265486725, 'Lung': 39.091418685121106, 'Muscle': 12.801387297633871, 'Nerve': 39.231147011308565, 'Ovary': 32.358111111111114, 'Pancreas': 8.251408536585366, 'Pituitary': 20.74756183745583, 'Prostate': 30.07522448979592, 'Salivary Gland': 20.357469135802468, 'Skin': 32.37302929795467, 'Small Intestine': 24.402032085561498, 'Spleen': 37.54157676348548, 'Stomach': 17.181211699164347, 'Testis': 34.808448753462606, 'Thyroid': 33.271163859111795, 'Uterus': 38.25401408450704, 'Vagina': 31.537884615384616} | [37.42, 45.2, 56.71, 57.57, 65.92, 71.8, 70.72, 70.19, 75.03, 81.06, 81.95, 82.13, 85.0, 89.84, 89.65, 93.29, 90.82, 89.33, 90.46, 84.59, 85.8, 87.81, 91.19, 89.54, 92.34, 94.82, 95.66, 94.94, 93.26, 90.29, 93.55, 91.65, 95.23, 95.54, 95.57, 95.25, 94.22, 93.77, 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1.0, 0.99, 1.0, 0.98, 0.99, 0.98, 0.97, 1.0, 0.99] | RING finger | Component of a SCF(SKP2)-like complex containing CUL1, SKP1, TRIM21 and SKP2. | SCF | null | IRF8, CALR, CUL1, FBXW11, HSPA5, IKBKB, IRF3, SKP1 , VCP,SKP2, DCP2 ,ULK1, BECN1,GABARAP, GABARAPL1, GABARAPL2 , MAP1LC3C,SQSTM1,IRF3 , NMI, IFI35 , CUL1, TRIM21 | USP4, IKBKB, TRIM21, CDKN1B, IRF3, IRF8, MNI | mono, 63 | null | UBE2D2, UBE2D1, UBE2E1, UBE2E2 | Homotrimer | null | 90.718042 | 0.406716 | 76.389834 | 0.438598 | 528 |
P19474 | Q13501 | 39172027 | Manual | TRIM21 | MASAARLTMMWEEVTCPICLDPFVEPVSIECGHSFCQECISQVGKGGGSVCPVCRQRFLLKNLRPNRQLANMVNNLKEISQEAREGTQGERCAVHGERLHLFCEKDGKALCWVCAQSRKHRDHAMVPLEEAAQEYQEKLQVALGELRRKQELAEKLEVEIAIKRADWKKTVETQKSRIHAEFVQQKNFLVEEEQRQLQELEKDEREQLRILGEKEAKLAQQSQALQELISELDRRCHSSALELLQEVIIVLERSESWNLKDLDITSPELRSVCHVPGLKKMLRTCAVHITLDPDTANPWLILSEDRRQVRLGDTQQSIPGNEERFDSYPMVLGAQHFHSGKHYWEVDVTGKEAWDLGVCRDSVRRKGHFLLSSKSGFWTIWLWNKQKYEAGTYPQTPLHLQVPPCQVGIFLDYEAGMVSFYNITDHGSLIYSFSECAFTGPLRPFFSPGFNDGGKNTAPLTLCPLNIGSQGSTDY | Homo sapiens | Cytoplasm, Cytoplasmic vesicle, autophagosome, Nucleus, Cytoplasm, P-body, Cytoplasm, Stress granule | Low tissue specificity | {'Ciliated cells': '3.8', 'Basal respiratory cells': '6.8', 'Club cells': '5.8', 'Ionocytes': '3.7', 'Mucus glandular cells': '4.8', 'Serous glandular cells': '2.3', 'Gastric mucus-secreting cells': '8.8', 'Proximal enterocytes': '8.9', 'Paneth cells': '3.9', 'Distal enterocytes': '8.5', 'Intestinal goblet cells': '8.4', 'Exocrine glandular cells': '-0.716', 'Basal prostatic cells': '5.4', 'Prostatic glandular cells': '5.0', 'Breast glandular cells': '0.298', 'Breast myoepithelial cells': '0.351', 'Glandular and luminal cells': '5.9', 'Secretory cells': '8.4', 'Basal keratinocytes': '3.2', 'Suprabasal keratinocytes': '2.7', 'Basal squamous epithelial cells': '6.4', 'Squamous epithelial cells': '4.3', 'Alveolar cells type 1': '0.116', 'Alveolar cells type 2': '0.115', 'Salivary duct cells': '3.0', 'Ductal cells': '0.700', 'Hepatocytes': '0.503', 'Cholangiocytes': '11.4', 'Proximal tubular cells': '0.175', 'Distal tubular cells': '0.0', 'Collecting duct cells': '5.8', 'Mesothelial cells': '0.451', 'Sertoli cells': '0.479', 'Granulosa cells': '4.8', 'Enteroendocrine cells': '3.7', 'Pancreatic endocrine cells': '3.4', 'Leydig cells': '0.632', 'Excitatory neurons': '0.2', 'Inhibitory neurons': '0.1', 'Cone photoreceptor cells': '0.0', 'Rod photoreceptor cells': '0.0', 'Bipolar cells': '0.7', 'Horizontal cells': '0.6', 'Astrocytes': '0.0', 'Oligodendrocyte precursor cells': '0.9', 'Oligodendrocytes': '0.1', 'Microglial cells': '1.8', 'Muller glia cells': '2.4', 'Schwann cells': '0.099', 'Spermatogonia': '0.401', 'Spermatocytes': '-0.062', 'Early spermatids': '-0.578', 'Late spermatids': '-0.618', 'Oocytes': '1.5', 'Cytotrophoblasts': '6.6', 'Syncytiotrophoblasts': '9.8', 'Extravillous trophoblasts': '10.0', 'Endothelial cells': '7.8', 'Lymphatic endothelial cells': '6.9', 'Cardiomyocytes': '0.335', 'Skeletal myocytes': '-0.080', 'Smooth muscle cells': '6.3', 'Adipocytes': '8.3', 'Melanocytes': '0.101', 'Fibroblasts': '6.5', 'Peritubular cells': '0.579', 'Endometrial stromal cells': '4.5', 'Ovarian stromal cells': '6.7', 'Undifferentiated cells': '5.9', 'T-cells': '9.9', 'B-cells': '8.8', 'Plasma cells': '5.0', 'Nk-cells': '15.1', 'Granulocytes': '6.2', 'Monocytes': '7.8', 'Macrophages': '8.5', 'Hofbauer cells': '9.9', 'Kupffer cells': '10.3', 'Dendritic cells': '8.0', 'Langerhans cells': '0.466', 'Erythroid cells': '-0.084', 'Adipocytes (Subcutaneous)': '-0.368', 'Adipocytes (Visceral)': '-0.167', 'Breast glandular cells (progenitors)': '0.190', 'Adipocytes (Breast)': '-0.382', 'Colon enterocytes': '0.004', 'Colon enteroendocrine cells': '0.196', 'Enteric glia cells': '-0.129', 'Mitotic cells (Colon)': '0.005', 'Mitotic cells (Heart)': '0.486', 'Podocytes': '-0.114', 'Ascending Loop of Henle cells': '0.371', 'Intercalated cells': '-0.097', 'Cholangiocyte': '0.375', 'NK-cells (Liver)': '-0.278', 'Respiratory ciliated cells': '-0.022', 'Mitotic cells (Lung)': '0.157', 'NK-cells (Lung)': '0.110', 'B-cells (Lung)': '-0.155', 'Alpha cells': '0.333', 'Beta cells': '0.161', 'Prostate glandular cells': '-0.162', 'Prostate basal glandular cells': '0.286', 'Urothelial cells': '0.283', 'Keratinocyte (other)': '0.121', 'Keratinocyte (granular)': '-0.008', 'Hair cortex cells': '-0.113', 'Inner root sheath cells': '-0.069', 'Outer root sheath cells': '0.125', 'Sebaceous gland cells': '0.110', 'Eccrine sweat gland cells': '0.070', 'Adipocytes (Skin)': '0.019', 'Mitotic cells (Skin)': '0.236', 'Parietal cells': '-0.609', 'Chief cells': '-0.599', 'Gastric mucous cells': '-0.193', 'Gastric enteroendocrine cells': '-0.441', 'Mitotic cells (Stomach)': '0.261', 'Parafollicular cells': '-0.028', 'Thyroid glandular cells': '0.094', 'Mitotic cells (Thyroid)': '0.242', 'Adrenal cortex cells': '0.619', 'Adrenal medulla cells': '0.063', 'Mitotic cells (Adrenal gland)': '0.483', 'Minor salivary glandular cells': '0.582', 'Minor salivary gland ductal cells': '0.072', 'Minor salivary gland basal cells': '0.229', 'Mitotic cells (Minor salivary gland)': '0.376', 'Adipocytes (Minor salivary gland)': '0.211', 'Somatotropes': '-0.121', 'Lactotropes': '-0.287', 'Gonadotropes': '0.004', 'Corticotropes': '-0.352', 'Thyrotropes': '-0.054', 'Undifferentiated cells (Pituitary gland)': '0.486', 'Mitotic cells (Spleen)': '-0.016', 'Platelets': '0.115', 'Erythrocytes': '0.098', 'Hematopoietic stem cells': '0.042', 'B-cells (Spleen)': '0.028', 'NK-cells (Spleen)': '0.157', 'Amygdala excitatory': '0.1', 'Cerebellar inhibitory': '0.2', 'Cge interneuron': '0.3', 'Deep-layer corticothalamic and 6b': '0.3', 'Deep-layer intratelencephalic': '0.1', 'Deep-layer near-projecting': '0.1', 'Eccentric medium spiny neuron': '0.4', 'Hippocampal ca1-3': '0.5', 'Hippocampal ca4': '0.1', 'Hippocampal dentate gyrus': '0.3', 'Lamp5-lhx6 and chandelier': '0.3', 'Lower rhombic lip': '0.2', 'Mammillary body': '0.4', 'Medium spiny neuron': '0.6', 'Mge interneuron': '0.1', 'Midbrain-derived inhibitory': '0.6', 'Miscellaneous': '0.6', 'Splatter': '0.5', 'Thalamic excitatory': '1.3', 'Upper rhombic lip': '0.1', 'Upper-layer intratelencephalic': '0.1', 'Astrocyte': '1.5', 'Bergmann glia': '1.5', 'Central nervous system macrophage': '6.0', 'Choroid plexus epithelial cell': '2.9', 'Committed oligodendrocyte precursor': '1.0', 'Ependymal cell': '1.3', 'Oligodendrocyte': '0.1', 'Oligodendrocyte precursor cell': '2.3', 'Endothelial cell': '6.4', 'Pericyte': '5.3', 'Vascular associated smooth muscle cell': '3.1', 'Fibroblast': '5.3', 'Leukocyte': '7.4', 'Basophil': '107.0', 'Eosinophil': '312.5', 'Neutrophil': '496.9', 'Classical monocyte': '25.8', 'Non-classical monocyte': '66.1', 'Intermediate monocyte': '117.0', 'T-reg': '72.1', 'GdT-cell': '89.5', 'MAIT T-cell': '61.2', 'Memory CD4 T-cell': '76.8', 'Naive CD4 T-cell': '47.0', 'Memory CD8 T-cell': '81.1', 'Naive CD8 T-cell': '43.5', 'Memory B-cell': '50.4', 'Naive B-cell': '38.5', 'Plasmacytoid DC': '47.5', 'Myeloid DC': '92.2', 'NK-cell': '88.9', 'Total PBMC': '83.8', 'Vd2 gdTCR': '67.8', 'Memory CD4 T-cell Th1\\/Th17': '48.0', 'Memory CD4 T-cell Th17': '54.6', 'Memory CD4 T-cell Th2': '54.8', 'Non-Vd2 gdTCR': '73.7', 'Memory CD4 T-cell Th1': '58.8', 'Memory CD4 T-cell TFH': '61.9', 'Terminal effector memory CD4 T-cell': '72.8', 'Central memory CD8 T-cell': '59.9', 'Effector memory CD8 T-cell': '90.7', 'Terminal effector memory CD8 T-cell': '75.8', 'Non-switched memory B-cell': '52.6', 'Plasmablast': '62.3', 'Switched memory B-cell': '55.8', 'Exhausted memory B-cell': '52.1', 'Progenitor cell': '44.7', 'Memory T-reg': '82.4', 'Naive CD4 T-cell activated': '133.9', 'Naive CD8 T-cell activated': '163.4', 'Naive T-reg': '54.7'} | 2IWG, 5JPX, 5OLM, 6FGA, 6S53, 7BBD, 8A58 | {'Adipose Tissue': 21.42795099667774, 'Adrenal Gland': 16.707763565891472, 'Bladder': 21.861904761904764, 'Blood': 61.11958557588805, 'Blood Vessel': 22.62928389513109, 'Brain': 4.305000416351249, 'Breast': 20.001740740740743, 'Cervix Uteri': 26.420526315789473, 'Colon': 23.40817458279846, 'Esophagus': 21.74157577854671, 'Fallopian Tube': 25.39, 'Heart': 6.66628106852497, 'Kidney': 13.61479775280899, 'Liver': 10.388, 'Lung': 32.00464878892734, 'Muscle': 3.944284806973848, 'Nerve': 25.39305008077545, 'Ovary': 30.51811111111111, 'Pancreas': 6.808080182926829, 'Pituitary': 12.995699646643107, 'Prostate': 21.00597551020408, 'Salivary Gland': 16.434148148148147, 'Skin': 17.851811498065228, 'Small Intestine': 28.907085561497325, 'Spleen': 50.16024896265561, 'Stomach': 19.072721448467966, 'Testis': 6.377013850415512, 'Thyroid': 21.553307810107196, 'Uterus': 29.83549295774648, 'Vagina': 21.551141025641027} | SQSTM1 | MASLTVKAYLLGKEDAAREIRRFSFCCSPEPEAEAEAAAGPGPCERLLSRVAALFPALRPGGFQAHYRDEDGDLVAFSSDEELTMAMSYVKDDIFRIYIKEKKECRRDHRPPCAQEAPRNMVHPNVICDGCNGPVVGTRYKCSVCPDYDLCSVCEGKGLHRGHTKLAFPSPFGHLSEGFSHSRWLRKVKHGHFGWPGWEMGPPGNWSPRPPRAGEARPGPTAESASGPSEDPSVNFLKNVGESVAAALSPLGIEVDIDVEHGGKRSRLTPVSPESSSTEEKSSSQPSSCCSDPSKPGGNVEGATQSLAEQMRKIALESEGRPEEQMESDNCSGGDDDWTHLSSKEVDPSTGELQSLQMPESEGPSSLDPSQEGPTGLKEAALYPHLPPEADPRLIESLSQMLSMGFSDEGGWLTRLLQTKNYDIGAALDTIQYSKHPPPL | Homo sapiens | Cytoplasmic vesicle, autophagosome, Preautophagosomal structure, Cytoplasm, cytosol, Nucleus, PML body, Late endosome, Lysosome, Nucleus, Endoplasmic reticulum, Cytoplasm, myofibril, sarcomere | Tissue enhanced (skeletal) | {'Ciliated cells': '254.9', 'Basal respiratory cells': '303.5', 'Club cells': '412.8', 'Ionocytes': '327.7', 'Mucus glandular cells': '545.4', 'Serous glandular cells': '241.1', 'Gastric mucus-secreting cells': '1156.1', 'Proximal enterocytes': '298.5', 'Paneth cells': '389.6', 'Distal enterocytes': '395.5', 'Intestinal goblet cells': '288.5', 'Exocrine glandular cells': '-0.553', 'Basal prostatic cells': '429.7', 'Prostatic glandular cells': '228.8', 'Breast glandular cells': '0.084', 'Breast myoepithelial cells': '0.100', 'Glandular and luminal cells': '559.1', 'Secretory cells': '266.7', 'Basal keratinocytes': '312.1', 'Suprabasal keratinocytes': '293.1', 'Basal squamous epithelial cells': '667.0', 'Squamous epithelial cells': '548.4', 'Alveolar cells type 1': '0.049', 'Alveolar cells type 2': '0.349', 'Salivary duct cells': '492.8', 'Ductal cells': '0.475', 'Hepatocytes': '0.458', 'Cholangiocytes': '299.5', 'Proximal tubular cells': '0.363', 'Distal tubular cells': '199.8', 'Collecting duct cells': '149.8', 'Mesothelial cells': '0.235', 'Sertoli cells': '0.501', 'Granulosa cells': '206.8', 'Enteroendocrine cells': '276.7', 'Pancreatic endocrine cells': '708.1', 'Leydig cells': '0.615', 'Excitatory neurons': '34.0', 'Inhibitory neurons': '35.6', 'Cone photoreceptor cells': '52.7', 'Rod photoreceptor cells': '66.0', 'Bipolar cells': '75.2', 'Horizontal cells': '66.1', 'Astrocytes': '35.0', 'Oligodendrocyte precursor cells': '15.6', 'Oligodendrocytes': '57.9', 'Microglial cells': '26.8', 'Muller glia cells': '140.9', 'Schwann cells': '0.000', 'Spermatogonia': '0.572', 'Spermatocytes': '0.178', 'Early spermatids': '-0.467', 'Late spermatids': '-0.596', 'Oocytes': '155.1', 'Cytotrophoblasts': '251.1', 'Syncytiotrophoblasts': '2518.9', 'Extravillous trophoblasts': '140.8', 'Endothelial cells': '266.9', 'Lymphatic endothelial cells': '277.6', 'Cardiomyocytes': '0.690', 'Skeletal myocytes': '-0.315', 'Smooth muscle cells': '271.4', 'Adipocytes': '375.3', 'Melanocytes': '-0.136', 'Fibroblasts': '407.1', 'Peritubular cells': '0.482', 'Endometrial stromal cells': '232.0', 'Ovarian stromal cells': '281.7', 'Undifferentiated cells': '142.4', 'T-cells': '238.5', 'B-cells': '255.1', 'Plasma cells': '481.3', 'Nk-cells': '241.5', 'Granulocytes': '709.7', 'Monocytes': '347.3', 'Macrophages': '391.1', 'Hofbauer cells': '276.8', 'Kupffer cells': '137.8', 'Dendritic cells': '178.7', 'Langerhans cells': '0.070', 'Erythroid cells': '-0.027', 'Adipocytes (Subcutaneous)': '0.147', 'Adipocytes (Visceral)': '-0.005', 'Breast glandular cells (progenitors)': '0.135', 'Adipocytes (Breast)': '-0.051', 'Colon enterocytes': '-0.073', 'Colon enteroendocrine cells': '0.157', 'Enteric glia cells': '-0.333', 'Mitotic cells (Colon)': '-0.049', 'Mitotic cells (Heart)': '0.414', 'Podocytes': '-0.044', 'Ascending Loop of Henle cells': '0.216', 'Intercalated cells': '-0.050', 'Cholangiocyte': '0.428', 'NK-cells (Liver)': '-0.358', 'Respiratory ciliated cells': 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36.33, 43.45, 41.19, 42.12, 41.03, 32.65, 35.92, 38.55, 44.08, 35.96, 34.17, 41.67, 42.61, 42.37, 49.83, 48.76, 47.15, 51.21, 51.96, 52.95, 55.42, 47.53, 45.08, 38.43, 37.42, 41.69, 42.05, 34.48, 39.04, 32.26, 38.29, 31.09, 35.92, 30.08, 35.67, 34.91, 33.18, 39.63, 35.75, 39.77, 37.98, 42.68, 36.62, 42.68, 41.23, 47.59, 59.33, 59.76, 46.36, 43.04, 43.31, 47.19, 47.02, 50.65, 53.67, 44.51, 48.8, 49.79, 56.16, 51.13, 57.36, 46.89, 41.88, 44.66, 41.32, 38.77, 40.81, 46.89, 36.67, 42.97, 42.32, 38.14, 41.13, 33.88, 34.86, 39.21, 30.23, 38.4, 36.53, 43.71, 36.85, 36.72, 45.42, 48.9, 52.62, 52.13, 53.41, 52.84, 50.5, 53.1, 59.17, 56.87, 61.37, 59.24, 58.97, 59.19, 59.12, 61.52, 66.39, 80.22, 84.78, 87.49, 90.43, 88.22, 90.4, 92.93, 92.73, 90.87, 92.24, 92.1, 91.46, 91.02, 88.89, 89.99, 90.61, 88.81, 88.82, 83.27, 85.85, 87.96, 90.29, 91.36, 91.17, 90.32, 92.12, 93.48, 91.8, 91.39, 92.23, 89.51, 90.41, 92.71, 91.36, 92.49, 91.39, 92.41, 92.35, 90.15, 88.67, 86.25, 78.79, 65.51, 60.25, 59.21, 54.33, 51.18, 56.34, 63.88, 49.86] | [0.84, 0.73, 0.66, 0.12, 0.4, 0.0, 0.15, 0.0, 0.16, 0.02, 0.08, 0.33, 0.91, 0.97, 0.48, 0.51, 0.52, 0.62, 0.35, 0.52, 0.25, 0.65, 0.1, 0.77, 0.07, 0.62, 0.26, 0.71, 0.8, 0.67, 0.83, 0.77, 0.89, 0.96, 0.73, 1.0, 0.81, 0.96, 0.97, 0.85, 0.58, 0.25, 0.27, 0.02, 0.57, 0.27, 0.01, 0.25, 0.51, 0.56, 0.0, 0.17, 0.78, 0.3, 0.0, 0.75, 0.61, 0.07, 0.84, 0.8, 0.71, 0.33, 0.13, 0.38, 0.01, 0.1, 0.09, 0.48, 0.25, 0.85, 0.8, 0.35, 0.59, 0.27, 0.28, 0.48, 0.01, 0.66, 0.32, 0.32, 0.72, 0.33, 0.0, 0.65, 0.57, 0.0, 0.25, 0.8, 0.39, 0.29, 0.72, 0.82, 0.61, 0.22, 0.02, 0.37, 0.0, 0.14, 0.0, 0.3, 0.38, 0.69, 0.82, 0.87, 0.73, 0.73, 0.77, 0.82, 0.74, 0.57, 0.64, 0.92, 0.8, 0.63, 0.87, 0.54, 0.26, 0.53, 0.67, 0.87, 0.31, 0.5, 0.05, 0.72, 0.97, 0.12, 0.65, 0.01, 0.41, 0.37, 0.54, 0.73, 0.23, 0.63, 0.0, 0.35, 0.1, 0.18, 0.23, 0.19, 0.33, 0.02, 0.57, 0.65, 0.28, 0.92, 0.77, 0.21, 0.08, 0.0, 0.09, 0.42, 0.61, 0.02, 0.32, 0.67, 0.67, 0.23, 0.32, 0.23, 0.72, 0.98, 0.34, 0.63, 0.28, 0.5, 0.57, 0.24, 0.49, 0.5, 0.31, 0.62, 0.83, 0.78, 0.86, 0.63, 1.0, 0.88, 0.87, 0.86, 0.82, 0.88, 0.99, 1.0, 1.0, 0.99, 1.0, 1.0, 0.98, 1.0, 0.95, 0.99, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 0.96, 1.0, 0.98, 1.0, 0.99, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 0.99, 1.0, 1.0, 1.0, 1.0, 0.98, 0.99, 0.99, 0.98, 1.0, 0.99, 1.0, 0.99, 0.99, 0.99, 0.92, 0.9, 0.91, 0.63, 0.51, 0.74, 0.44, 0.17, 0.44, 0.68, 0.44, 0.17, 0.55, 0.4, 0.15, 0.52, 0.54, 0.47, 0.07, 0.57, 0.62, 0.3, 0.63, 0.81, 0.69, 0.76, 0.47, 0.96, 0.26, 0.57, 0.07, 0.44, 0.05, 0.64, 0.4, 0.92, 0.94, 0.77, 0.67, 0.34, 0.63, 0.28, 0.69, 0.56, 0.88, 0.77, 0.91, 0.89, 0.91, 0.91, 0.92, 0.99, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 0.99, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 0.99, 1.0, 0.97, 0.98, 0.91, 0.98, 0.9, 0.99, 0.99, 0.97, 0.82, 0.79, 0.8, 0.68, 0.79, 0.72, 0.85, 0.84, 0.92, 0.91, 0.87, 0.99, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 0.99, 0.99, 1.0, 0.95, 0.95, 0.97, 0.91, 0.95, 0.78, 0.8, 0.85, 0.46, 0.85, 0.89, 0.79, 0.81, 0.67, 0.92, 0.87, 0.71, 0.98, 0.88, 0.88, 0.88, 0.82, 0.89, 0.88, 0.92, 0.99, 0.85, 0.98, 0.98, 1.0, 1.0, 0.99, 1.0, 1.0, 0.87, 0.91, 0.83, 0.9, 1.0, 0.9, 0.86, 0.84, 0.4, 0.87, 0.87, 0.41, 0.37, 0.83, 0.79, 0.29, 0.93, 0.69, 0.19, 0.58, 0.97, 0.93, 0.23, 0.46, 0.72, 0.59, 0.04, 0.16, 0.59, 0.07, 0.01, 0.23, 0.45, 0.0, 0.22, 0.77, 0.56, 0.83, 0.27, 0.52, 0.18, 0.79, 0.82, 0.19, 0.45, 0.0, 0.1, 0.68, 0.15, 0.0, 0.38, 0.69, 0.35, 0.77, 0.26, 0.5, 0.17, 0.43, 0.26, 0.0, 0.2, 0.54, 0.35, 0.15, 0.61, 0.7, 0.73, 0.82, 0.77, 0.84, 0.77, 0.96, 0.95] | RING finger | Component of a SCF(SKP2)-like complex containing CUL1, SKP1, TRIM21 and SKP2. | SCF | null | IRF8, CALR, CUL1, FBXW11, HSPA5, IKBKB, IRF3, SKP1 , VCP,SKP2, DCP2 ,ULK1, BECN1,GABARAP, GABARAPL1, GABARAPL2 , MAP1LC3C,SQSTM1,IRF3 , NMI, IFI35 , CUL1, TRIM21 | USP4, IKBKB, TRIM21, CDKN1B, IRF3, IRF8, MNI | mono, 63 | null | UBE2D2, UBE2D1, UBE2E1, UBE2E2 | Homotrimer | null | 90.718042 | 0.406716 | 67.094841 | 0.643591 | 1,803 |
P19474 | Q14653 | 18641315, 19494276, E3NethUbiquitome | UbiNet, UbiBrowser, 31181401 | TRIM21 | MASAARLTMMWEEVTCPICLDPFVEPVSIECGHSFCQECISQVGKGGGSVCPVCRQRFLLKNLRPNRQLANMVNNLKEISQEAREGTQGERCAVHGERLHLFCEKDGKALCWVCAQSRKHRDHAMVPLEEAAQEYQEKLQVALGELRRKQELAEKLEVEIAIKRADWKKTVETQKSRIHAEFVQQKNFLVEEEQRQLQELEKDEREQLRILGEKEAKLAQQSQALQELISELDRRCHSSALELLQEVIIVLERSESWNLKDLDITSPELRSVCHVPGLKKMLRTCAVHITLDPDTANPWLILSEDRRQVRLGDTQQSIPGNEERFDSYPMVLGAQHFHSGKHYWEVDVTGKEAWDLGVCRDSVRRKGHFLLSSKSGFWTIWLWNKQKYEAGTYPQTPLHLQVPPCQVGIFLDYEAGMVSFYNITDHGSLIYSFSECAFTGPLRPFFSPGFNDGGKNTAPLTLCPLNIGSQGSTDY | Homo sapiens | Cytoplasm, Cytoplasmic vesicle, autophagosome, Nucleus, Cytoplasm, P-body, Cytoplasm, Stress granule | Low tissue specificity | {'Ciliated cells': '3.8', 'Basal respiratory cells': '6.8', 'Club cells': '5.8', 'Ionocytes': '3.7', 'Mucus glandular cells': '4.8', 'Serous glandular cells': '2.3', 'Gastric mucus-secreting cells': '8.8', 'Proximal enterocytes': '8.9', 'Paneth cells': '3.9', 'Distal enterocytes': '8.5', 'Intestinal goblet cells': '8.4', 'Exocrine glandular cells': '-0.716', 'Basal prostatic cells': '5.4', 'Prostatic glandular cells': '5.0', 'Breast glandular cells': '0.298', 'Breast myoepithelial cells': '0.351', 'Glandular and luminal cells': '5.9', 'Secretory cells': '8.4', 'Basal keratinocytes': '3.2', 'Suprabasal keratinocytes': '2.7', 'Basal squamous epithelial cells': '6.4', 'Squamous epithelial cells': '4.3', 'Alveolar cells type 1': '0.116', 'Alveolar cells type 2': '0.115', 'Salivary duct cells': '3.0', 'Ductal cells': '0.700', 'Hepatocytes': '0.503', 'Cholangiocytes': '11.4', 'Proximal tubular cells': '0.175', 'Distal tubular cells': '0.0', 'Collecting duct cells': '5.8', 'Mesothelial cells': '0.451', 'Sertoli cells': '0.479', 'Granulosa cells': '4.8', 'Enteroendocrine cells': '3.7', 'Pancreatic endocrine cells': '3.4', 'Leydig cells': '0.632', 'Excitatory neurons': '0.2', 'Inhibitory neurons': '0.1', 'Cone photoreceptor cells': '0.0', 'Rod photoreceptor cells': '0.0', 'Bipolar cells': '0.7', 'Horizontal cells': '0.6', 'Astrocytes': '0.0', 'Oligodendrocyte precursor cells': '0.9', 'Oligodendrocytes': '0.1', 'Microglial cells': '1.8', 'Muller glia cells': '2.4', 'Schwann cells': '0.099', 'Spermatogonia': '0.401', 'Spermatocytes': '-0.062', 'Early spermatids': '-0.578', 'Late spermatids': '-0.618', 'Oocytes': '1.5', 'Cytotrophoblasts': '6.6', 'Syncytiotrophoblasts': '9.8', 'Extravillous trophoblasts': '10.0', 'Endothelial cells': '7.8', 'Lymphatic endothelial cells': '6.9', 'Cardiomyocytes': '0.335', 'Skeletal myocytes': '-0.080', 'Smooth muscle cells': '6.3', 'Adipocytes': '8.3', 'Melanocytes': '0.101', 'Fibroblasts': '6.5', 'Peritubular cells': '0.579', 'Endometrial stromal cells': '4.5', 'Ovarian stromal cells': '6.7', 'Undifferentiated cells': '5.9', 'T-cells': '9.9', 'B-cells': '8.8', 'Plasma cells': '5.0', 'Nk-cells': '15.1', 'Granulocytes': '6.2', 'Monocytes': '7.8', 'Macrophages': '8.5', 'Hofbauer cells': '9.9', 'Kupffer cells': '10.3', 'Dendritic cells': '8.0', 'Langerhans cells': '0.466', 'Erythroid cells': '-0.084', 'Adipocytes (Subcutaneous)': '-0.368', 'Adipocytes (Visceral)': '-0.167', 'Breast glandular cells (progenitors)': '0.190', 'Adipocytes (Breast)': '-0.382', 'Colon enterocytes': '0.004', 'Colon enteroendocrine cells': '0.196', 'Enteric glia cells': '-0.129', 'Mitotic cells (Colon)': '0.005', 'Mitotic cells (Heart)': '0.486', 'Podocytes': '-0.114', 'Ascending Loop of Henle cells': '0.371', 'Intercalated cells': '-0.097', 'Cholangiocyte': '0.375', 'NK-cells (Liver)': '-0.278', 'Respiratory ciliated cells': '-0.022', 'Mitotic cells (Lung)': '0.157', 'NK-cells (Lung)': '0.110', 'B-cells (Lung)': '-0.155', 'Alpha cells': '0.333', 'Beta cells': '0.161', 'Prostate glandular cells': '-0.162', 'Prostate basal glandular cells': '0.286', 'Urothelial cells': '0.283', 'Keratinocyte (other)': '0.121', 'Keratinocyte (granular)': '-0.008', 'Hair cortex cells': '-0.113', 'Inner root sheath cells': '-0.069', 'Outer root sheath cells': '0.125', 'Sebaceous gland cells': '0.110', 'Eccrine sweat gland cells': '0.070', 'Adipocytes (Skin)': '0.019', 'Mitotic cells (Skin)': '0.236', 'Parietal cells': '-0.609', 'Chief cells': '-0.599', 'Gastric mucous cells': '-0.193', 'Gastric enteroendocrine cells': '-0.441', 'Mitotic cells (Stomach)': '0.261', 'Parafollicular cells': '-0.028', 'Thyroid glandular cells': '0.094', 'Mitotic cells (Thyroid)': '0.242', 'Adrenal cortex cells': '0.619', 'Adrenal medulla cells': '0.063', 'Mitotic cells (Adrenal gland)': '0.483', 'Minor salivary glandular cells': '0.582', 'Minor salivary gland ductal cells': '0.072', 'Minor salivary gland basal cells': '0.229', 'Mitotic cells (Minor salivary gland)': '0.376', 'Adipocytes (Minor salivary gland)': '0.211', 'Somatotropes': '-0.121', 'Lactotropes': '-0.287', 'Gonadotropes': '0.004', 'Corticotropes': '-0.352', 'Thyrotropes': '-0.054', 'Undifferentiated cells (Pituitary gland)': '0.486', 'Mitotic cells (Spleen)': '-0.016', 'Platelets': '0.115', 'Erythrocytes': '0.098', 'Hematopoietic stem cells': '0.042', 'B-cells (Spleen)': '0.028', 'NK-cells (Spleen)': '0.157', 'Amygdala excitatory': '0.1', 'Cerebellar inhibitory': '0.2', 'Cge interneuron': '0.3', 'Deep-layer corticothalamic and 6b': '0.3', 'Deep-layer intratelencephalic': '0.1', 'Deep-layer near-projecting': '0.1', 'Eccentric medium spiny neuron': '0.4', 'Hippocampal ca1-3': '0.5', 'Hippocampal ca4': '0.1', 'Hippocampal dentate gyrus': '0.3', 'Lamp5-lhx6 and chandelier': '0.3', 'Lower rhombic lip': '0.2', 'Mammillary body': '0.4', 'Medium spiny neuron': '0.6', 'Mge interneuron': '0.1', 'Midbrain-derived inhibitory': '0.6', 'Miscellaneous': '0.6', 'Splatter': '0.5', 'Thalamic excitatory': '1.3', 'Upper rhombic lip': '0.1', 'Upper-layer intratelencephalic': '0.1', 'Astrocyte': '1.5', 'Bergmann glia': '1.5', 'Central nervous system macrophage': '6.0', 'Choroid plexus epithelial cell': '2.9', 'Committed oligodendrocyte precursor': '1.0', 'Ependymal cell': '1.3', 'Oligodendrocyte': '0.1', 'Oligodendrocyte precursor cell': '2.3', 'Endothelial cell': '6.4', 'Pericyte': '5.3', 'Vascular associated smooth muscle cell': '3.1', 'Fibroblast': '5.3', 'Leukocyte': '7.4', 'Basophil': '107.0', 'Eosinophil': '312.5', 'Neutrophil': '496.9', 'Classical monocyte': '25.8', 'Non-classical monocyte': '66.1', 'Intermediate monocyte': '117.0', 'T-reg': '72.1', 'GdT-cell': '89.5', 'MAIT T-cell': '61.2', 'Memory CD4 T-cell': '76.8', 'Naive CD4 T-cell': '47.0', 'Memory CD8 T-cell': '81.1', 'Naive CD8 T-cell': '43.5', 'Memory B-cell': '50.4', 'Naive B-cell': '38.5', 'Plasmacytoid DC': '47.5', 'Myeloid DC': '92.2', 'NK-cell': '88.9', 'Total PBMC': '83.8', 'Vd2 gdTCR': '67.8', 'Memory CD4 T-cell Th1\\/Th17': '48.0', 'Memory CD4 T-cell Th17': '54.6', 'Memory CD4 T-cell Th2': '54.8', 'Non-Vd2 gdTCR': '73.7', 'Memory CD4 T-cell Th1': '58.8', 'Memory CD4 T-cell TFH': '61.9', 'Terminal effector memory CD4 T-cell': '72.8', 'Central memory CD8 T-cell': '59.9', 'Effector memory CD8 T-cell': '90.7', 'Terminal effector memory CD8 T-cell': '75.8', 'Non-switched memory B-cell': '52.6', 'Plasmablast': '62.3', 'Switched memory B-cell': '55.8', 'Exhausted memory B-cell': '52.1', 'Progenitor cell': '44.7', 'Memory T-reg': '82.4', 'Naive CD4 T-cell activated': '133.9', 'Naive CD8 T-cell activated': '163.4', 'Naive T-reg': '54.7'} | 2IWG, 5JPX, 5OLM, 6FGA, 6S53, 7BBD, 8A58 | {'Adipose Tissue': 21.42795099667774, 'Adrenal Gland': 16.707763565891472, 'Bladder': 21.861904761904764, 'Blood': 61.11958557588805, 'Blood Vessel': 22.62928389513109, 'Brain': 4.305000416351249, 'Breast': 20.001740740740743, 'Cervix Uteri': 26.420526315789473, 'Colon': 23.40817458279846, 'Esophagus': 21.74157577854671, 'Fallopian Tube': 25.39, 'Heart': 6.66628106852497, 'Kidney': 13.61479775280899, 'Liver': 10.388, 'Lung': 32.00464878892734, 'Muscle': 3.944284806973848, 'Nerve': 25.39305008077545, 'Ovary': 30.51811111111111, 'Pancreas': 6.808080182926829, 'Pituitary': 12.995699646643107, 'Prostate': 21.00597551020408, 'Salivary Gland': 16.434148148148147, 'Skin': 17.851811498065228, 'Small Intestine': 28.907085561497325, 'Spleen': 50.16024896265561, 'Stomach': 19.072721448467966, 'Testis': 6.377013850415512, 'Thyroid': 21.553307810107196, 'Uterus': 29.83549295774648, 'Vagina': 21.551141025641027} | IRF3 | MGTPKPRILPWLVSQLDLGQLEGVAWVNKSRTRFRIPWKHGLRQDAQQEDFGIFQAWAEATGAYVPGRDKPDLPTWKRNFRSALNRKEGLRLAEDRSKDPHDPHKIYEFVNSGVGDFSQPDTSPDTNGGGSTSDTQEDILDELLGNMVLAPLPDPGPPSLAVAPEPCPQPLRSPSLDNPTPFPNLGPSENPLKRLLVPGEEWEFEVTAFYRGRQVFQQTISCPEGLRLVGSEVGDRTLPGWPVTLPDPGMSLTDRGVMSYVRHVLSCLGGGLALWRAGQWLWAQRLGHCHTYWAVSEELLPNSGHGPDGEVPKDKEGGVFDLGPFIVDLITFTEGSGRSPRYALWFCVGESWPQDQPWTKRLVMVKVVPTCLRALVEMARVGGASSLENTVDLHISNSHPLSLTSDQYKAYLQDLVEGMDFQGPGES | Homo sapiens | Cytoplasm, Nucleus, Mitochondrion | Low tissue specificity | {'Ciliated cells': '43.9', 'Basal respiratory cells': '55.3', 'Club cells': '46.8', 'Ionocytes': '62.2', 'Mucus glandular cells': '34.1', 'Serous glandular cells': '40.7', 'Gastric mucus-secreting cells': '65.4', 'Proximal enterocytes': '65.5', 'Paneth cells': '52.7', 'Distal enterocytes': '66.8', 'Intestinal goblet cells': '63.5', 'Exocrine glandular cells': '-0.649', 'Basal prostatic cells': '54.1', 'Prostatic glandular cells': '40.6', 'Breast glandular cells': '0.683', 'Breast myoepithelial cells': '0.619', 'Glandular and luminal cells': '35.6', 'Secretory cells': '40.5', 'Basal keratinocytes': '45.8', 'Suprabasal keratinocytes': '41.4', 'Basal squamous epithelial cells': '24.4', 'Squamous epithelial cells': '21.5', 'Alveolar cells type 1': '0.023', 'Alveolar cells type 2': '-0.529', 'Salivary duct cells': '43.2', 'Ductal cells': '0.497', 'Hepatocytes': '0.088', 'Cholangiocytes': '36.2', 'Proximal tubular cells': '0.161', 'Distal tubular cells': '27.7', 'Collecting duct cells': '35.0', 'Mesothelial cells': '0.454', 'Sertoli cells': '0.250', 'Granulosa cells': '34.9', 'Enteroendocrine cells': '43.5', 'Pancreatic endocrine cells': '40.8', 'Leydig cells': '0.343', 'Excitatory neurons': '3.8', 'Inhibitory neurons': '5.4', 'Cone photoreceptor cells': '22.1', 'Rod photoreceptor cells': '43.1', 'Bipolar cells': '30.2', 'Horizontal cells': '22.7', 'Astrocytes': '15.2', 'Oligodendrocyte precursor cells': '6.6', 'Oligodendrocytes': '10.0', 'Microglial cells': '9.8', 'Muller glia cells': '31.8', 'Schwann cells': '0.062', 'Spermatogonia': '0.105', 'Spermatocytes': '-0.098', 'Early spermatids': '-0.434', 'Late spermatids': '-0.414', 'Oocytes': '17.6', 'Cytotrophoblasts': '80.3', 'Syncytiotrophoblasts': '49.9', 'Extravillous trophoblasts': '100.9', 'Endothelial cells': '36.2', 'Lymphatic endothelial cells': '55.3', 'Cardiomyocytes': '0.279', 'Skeletal myocytes': '0.005', 'Smooth muscle cells': '32.2', 'Adipocytes': '40.9', 'Melanocytes': '-0.153', 'Fibroblasts': '31.8', 'Peritubular cells': '0.352', 'Endometrial stromal cells': '29.0', 'Ovarian stromal cells': '57.8', 'Undifferentiated cells': '46.1', 'T-cells': '66.3', 'B-cells': '46.6', 'Plasma cells': '65.3', 'Nk-cells': '86.5', 'Granulocytes': '46.1', 'Monocytes': '26.7', 'Macrophages': '36.6', 'Hofbauer cells': '44.4', 'Kupffer cells': '28.2', 'Dendritic cells': '31.5', 'Langerhans cells': '0.146', 'Erythroid cells': '0.064', 'Adipocytes (Subcutaneous)': '-0.472', 'Adipocytes (Visceral)': '-0.455', 'Breast glandular cells (progenitors)': '0.478', 'Adipocytes (Breast)': '-0.644', 'Colon enterocytes': '0.005', 'Colon enteroendocrine cells': '0.078', 'Enteric glia cells': '0.448', 'Mitotic cells (Colon)': '0.065', 'Mitotic cells (Heart)': '0.363', 'Podocytes': '-0.059', 'Ascending Loop of Henle cells': '0.364', 'Intercalated cells': '-0.054', 'Cholangiocyte': '0.276', 'NK-cells (Liver)': '-0.053', 'Respiratory ciliated cells': '0.184', 'Mitotic cells (Lung)': '-0.143', 'NK-cells (Lung)': '0.379', 'B-cells (Lung)': '0.295', 'Alpha cells': '0.388', 'Beta cells': '0.274', 'Prostate glandular cells': '0.129', 'Prostate basal glandular cells': '0.442', 'Urothelial 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94.0, 93.88, 92.58, 93.65, 93.92, 92.02, 89.32, 88.19, 89.59, 92.82, 96.43, 96.83, 97.8, 97.89, 98.3, 98.15, 97.6, 95.93, 95.26, 91.33, 90.45, 90.53, 94.29, 94.66, 95.94, 97.18, 95.39, 95.72, 94.54, 93.72, 92.93, 92.02, 93.2, 95.36, 96.92, 96.57, 96.83, 95.56, 91.7, 74.91, 66.87, 59.92, 66.17, 79.69, 80.75, 88.1, 89.97, 90.47, 91.96, 93.84, 94.83, 95.61, 95.7, 95.65, 93.67, 91.39, 86.67, 80.5, 63.31, 59.45, 49.67, 59.63, 67.24, 71.82, 78.32, 81.79, 85.53, 87.28, 90.81, 92.67, 92.19, 92.23, 94.07, 94.75, 92.43, 93.6, 94.05, 91.77, 92.71, 95.08, 97.09, 97.55, 98.31, 97.6, 96.71, 94.89, 93.89, 95.46, 97.28, 98.03, 98.28, 98.41, 98.03, 96.84, 94.82, 92.15, 93.22, 95.86, 97.84, 98.34, 98.15, 98.25, 97.63, 97.33, 94.26, 91.38, 89.13, 89.23, 89.74, 82.33, 75.07, 70.56, 71.19, 83.07, 90.69, 95.77, 96.1, 96.77, 98.09, 98.35, 97.89, 96.11, 90.35, 94.26, 95.28, 96.76, 97.35, 97.94, 98.16, 97.22, 97.29, 96.81, 95.95, 97.68, 97.47, 97.03, 96.77, 97.11, 96.27, 96.24, 95.68, 93.12, 92.49, 90.78, 91.08, 88.36, 91.94, 93.21, 95.96, 96.24, 97.57, 97.82, 98.43, 98.41, 98.47, 97.85, 97.86, 96.0, 95.7, 95.65, 96.34, 92.6, 91.72, 88.59, 88.35, 91.07, 93.64, 92.18, 91.16, 94.46, 95.03, 96.83, 97.97, 98.35, 98.34, 98.54, 98.32, 97.94, 96.08, 96.72, 97.79, 96.46, 94.35, 96.24, 95.54, 92.22, 92.03, 92.82, 90.44, 87.91, 81.22, 78.03, 77.6, 77.27, 78.13, 79.04, 81.54, 84.04, 85.55, 86.38, 89.67, 85.98, 83.82, 79.66, 78.14, 81.9, 82.01, 84.93, 89.72, 89.3, 90.55, 90.38, 91.21, 91.21, 91.28, 93.18, 93.89, 93.71, 94.91, 95.99, 96.17, 96.04, 95.55, 94.58, 94.09, 92.83, 88.27, 91.82, 86.89, 81.57, 71.52, 55.77, 50.42, 50.86, 38.84, 34.74] | [0.98, 0.94, 0.92, 0.89, 0.82, 0.32, 0.56, 0.04, 0.14, 0.5, 0.14, 0.0, 0.3, 0.46, 0.18, 0.05, 0.51, 0.5, 0.59, 0.74, 0.21, 0.4, 0.23, 0.04, 0.38, 0.21, 0.44, 0.31, 0.96, 0.64, 0.54, 0.25, 0.37, 0.0, 0.27, 0.0, 0.12, 0.03, 0.1, 0.27, 0.44, 0.58, 0.23, 0.5, 0.18, 0.25, 0.24, 0.46, 0.59, 0.22, 0.08, 0.21, 0.03, 0.02, 0.22, 0.21, 0.09, 0.04, 0.41, 0.32, 0.25, 0.59, 0.55, 0.12, 0.45, 0.59, 0.91, 0.86, 0.4, 0.93, 0.63, 0.39, 0.31, 0.25, 0.28, 0.04, 0.1, 0.51, 0.46, 0.0, 0.15, 0.38, 0.2, 0.02, 0.63, 0.79, 0.33, 0.83, 0.3, 0.14, 0.56, 0.49, 0.44, 0.33, 0.52, 0.45, 0.15, 0.94, 0.35, 0.72, 0.6, 0.4, 0.07, 0.08, 0.06, 0.1, 0.04, 0.13, 0.17, 0.42, 0.83, 0.74, 0.92, 0.92, 1.0, 0.72, 0.73, 0.6, 0.81, 0.81, 0.88, 0.79, 0.96, 0.89, 1.0, 0.99, 1.0, 1.0, 1.0, 1.0, 0.93, 0.97, 0.73, 0.48, 0.67, 0.71, 0.28, 0.32, 0.56, 0.34, 0.21, 0.66, 0.58, 0.31, 0.6, 0.8, 0.82, 0.88, 0.92, 0.95, 0.96, 0.98, 0.98, 0.96, 0.97, 0.87, 1.0, 0.99, 1.0, 0.99, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 0.97, 1.0, 0.95, 0.9, 0.91, 0.84, 0.95, 0.75, 0.97, 0.75, 0.89, 0.1, 0.2, 0.0, 0.39, 0.27, 0.0, 0.26, 0.45, 0.93, 0.8, 0.16, 0.24, 0.02, 0.3, 0.03, 0.15, 0.0, 0.02, 0.0, 0.11, 0.03, 0.28, 0.13, 0.54, 0.43, 0.37, 0.18, 0.59, 0.41, 0.55, 0.05, 0.44, 0.23, 0.68, 0.57, 0.03, 0.02, 0.06, 0.03, 0.08, 0.06, 0.61, 0.61, 0.82, 0.51, 0.52, 0.85, 0.81, 0.31, 0.57, 0.14, 0.52, 0.59, 0.0, 0.49, 0.02, 0.32, 0.5, 0.21, 0.4, 0.76, 0.47, 0.86, 0.57, 0.42, 0.65, 0.55, 0.35, 0.15, 0.48, 0.62, 0.0, 0.31, 0.57, 0.08, 0.06, 0.41, 0.32, 0.05, 0.47, 0.13, 0.04, 0.03, 0.07, 0.02, 0.25, 0.19, 0.47, 0.44, 0.1, 0.24, 0.0, 0.19, 0.0, 0.2, 0.11, 0.28, 0.06, 0.69, 0.1, 0.47, 0.03, 0.27, 0.13, 0.03, 0.2, 0.05, 0.55, 0.25, 0.72, 0.41, 0.01, 0.2, 0.4, 0.53, 0.84, 0.19, 0.36, 0.53, 0.23, 0.44, 0.02, 0.25, 0.45, 0.95, 0.74, 0.58, 0.18, 0.33, 0.04, 0.07, 0.19, 0.0, 0.0, 0.44, 0.03, 0.0, 0.41, 0.5, 0.0, 0.13, 0.3, 0.23, 0.16, 0.65, 0.73, 0.69, 0.45, 0.75, 0.35, 0.09, 0.26, 0.11, 0.0, 0.0, 0.01, 0.01, 0.0, 0.03, 0.45, 0.26, 0.65, 0.07, 0.0, 0.51, 0.89, 0.51, 0.49, 0.07, 0.03, 0.53, 0.06, 0.12, 0.0, 0.0, 0.0, 0.08, 0.01, 0.0, 0.0, 0.09, 0.0, 0.0, 0.27, 0.18, 0.0, 0.02, 0.49, 0.04, 0.09, 0.52, 0.37, 0.08, 0.77, 0.82, 0.34, 0.75, 0.73, 0.63, 0.18, 0.71, 0.02, 0.36, 0.03, 0.35, 0.07, 0.27, 0.77, 0.29, 0.68, 0.6, 0.1, 0.52, 0.06, 0.25, 0.13, 0.72, 0.4, 0.02, 0.36, 0.54, 0.19, 0.0, 0.45, 0.34, 0.02, 0.1, 0.71, 0.7, 0.08, 0.68, 0.57, 0.73, 0.48, 0.51, 0.83, 0.7, 0.94] | RING finger | Component of a SCF(SKP2)-like complex containing CUL1, SKP1, TRIM21 and SKP2. | SCF | null | IRF8, CALR, CUL1, FBXW11, HSPA5, IKBKB, IRF3, SKP1 , VCP,SKP2, DCP2 ,ULK1, BECN1,GABARAP, GABARAPL1, GABARAPL2 , MAP1LC3C,SQSTM1,IRF3 , NMI, IFI35 , CUL1, TRIM21 | USP4, IKBKB, TRIM21, CDKN1B, IRF3, IRF8, MNI | mono, 63 | null | UBE2D2, UBE2D1, UBE2E1, UBE2E2 | Homotrimer | null | 90.718042 | 0.406716 | 79.871358 | 0.426393 | 1,856 |
P19474 | Q16666 | 33061806 | UbiBrowser | TRIM21 | MASAARLTMMWEEVTCPICLDPFVEPVSIECGHSFCQECISQVGKGGGSVCPVCRQRFLLKNLRPNRQLANMVNNLKEISQEAREGTQGERCAVHGERLHLFCEKDGKALCWVCAQSRKHRDHAMVPLEEAAQEYQEKLQVALGELRRKQELAEKLEVEIAIKRADWKKTVETQKSRIHAEFVQQKNFLVEEEQRQLQELEKDEREQLRILGEKEAKLAQQSQALQELISELDRRCHSSALELLQEVIIVLERSESWNLKDLDITSPELRSVCHVPGLKKMLRTCAVHITLDPDTANPWLILSEDRRQVRLGDTQQSIPGNEERFDSYPMVLGAQHFHSGKHYWEVDVTGKEAWDLGVCRDSVRRKGHFLLSSKSGFWTIWLWNKQKYEAGTYPQTPLHLQVPPCQVGIFLDYEAGMVSFYNITDHGSLIYSFSECAFTGPLRPFFSPGFNDGGKNTAPLTLCPLNIGSQGSTDY | Homo sapiens | Cytoplasm, Cytoplasmic vesicle, autophagosome, Nucleus, Cytoplasm, P-body, Cytoplasm, Stress granule | Low tissue specificity | {'Ciliated cells': '3.8', 'Basal respiratory cells': '6.8', 'Club cells': '5.8', 'Ionocytes': '3.7', 'Mucus glandular cells': '4.8', 'Serous glandular cells': '2.3', 'Gastric mucus-secreting cells': '8.8', 'Proximal enterocytes': '8.9', 'Paneth cells': '3.9', 'Distal enterocytes': '8.5', 'Intestinal goblet cells': '8.4', 'Exocrine glandular cells': '-0.716', 'Basal prostatic cells': '5.4', 'Prostatic glandular cells': '5.0', 'Breast glandular cells': '0.298', 'Breast myoepithelial cells': '0.351', 'Glandular and luminal cells': '5.9', 'Secretory cells': '8.4', 'Basal keratinocytes': '3.2', 'Suprabasal keratinocytes': '2.7', 'Basal squamous epithelial cells': '6.4', 'Squamous epithelial cells': '4.3', 'Alveolar cells type 1': '0.116', 'Alveolar cells type 2': '0.115', 'Salivary duct cells': '3.0', 'Ductal cells': '0.700', 'Hepatocytes': '0.503', 'Cholangiocytes': '11.4', 'Proximal tubular cells': '0.175', 'Distal tubular cells': '0.0', 'Collecting duct cells': '5.8', 'Mesothelial cells': '0.451', 'Sertoli cells': '0.479', 'Granulosa cells': '4.8', 'Enteroendocrine cells': '3.7', 'Pancreatic endocrine cells': '3.4', 'Leydig cells': '0.632', 'Excitatory neurons': '0.2', 'Inhibitory neurons': '0.1', 'Cone photoreceptor cells': '0.0', 'Rod photoreceptor cells': '0.0', 'Bipolar cells': '0.7', 'Horizontal cells': '0.6', 'Astrocytes': '0.0', 'Oligodendrocyte precursor cells': '0.9', 'Oligodendrocytes': '0.1', 'Microglial cells': '1.8', 'Muller glia cells': '2.4', 'Schwann cells': '0.099', 'Spermatogonia': '0.401', 'Spermatocytes': '-0.062', 'Early spermatids': '-0.578', 'Late spermatids': '-0.618', 'Oocytes': '1.5', 'Cytotrophoblasts': '6.6', 'Syncytiotrophoblasts': '9.8', 'Extravillous trophoblasts': '10.0', 'Endothelial cells': '7.8', 'Lymphatic endothelial cells': '6.9', 'Cardiomyocytes': '0.335', 'Skeletal myocytes': '-0.080', 'Smooth muscle cells': '6.3', 'Adipocytes': '8.3', 'Melanocytes': '0.101', 'Fibroblasts': '6.5', 'Peritubular cells': '0.579', 'Endometrial stromal cells': '4.5', 'Ovarian stromal cells': '6.7', 'Undifferentiated cells': '5.9', 'T-cells': '9.9', 'B-cells': '8.8', 'Plasma cells': '5.0', 'Nk-cells': '15.1', 'Granulocytes': '6.2', 'Monocytes': '7.8', 'Macrophages': '8.5', 'Hofbauer cells': '9.9', 'Kupffer cells': '10.3', 'Dendritic cells': '8.0', 'Langerhans cells': '0.466', 'Erythroid cells': '-0.084', 'Adipocytes (Subcutaneous)': '-0.368', 'Adipocytes (Visceral)': '-0.167', 'Breast glandular cells (progenitors)': '0.190', 'Adipocytes (Breast)': '-0.382', 'Colon enterocytes': '0.004', 'Colon enteroendocrine cells': '0.196', 'Enteric glia cells': '-0.129', 'Mitotic cells (Colon)': '0.005', 'Mitotic cells (Heart)': '0.486', 'Podocytes': '-0.114', 'Ascending Loop of Henle cells': '0.371', 'Intercalated cells': '-0.097', 'Cholangiocyte': '0.375', 'NK-cells (Liver)': '-0.278', 'Respiratory ciliated cells': '-0.022', 'Mitotic cells (Lung)': '0.157', 'NK-cells (Lung)': '0.110', 'B-cells (Lung)': '-0.155', 'Alpha cells': '0.333', 'Beta cells': '0.161', 'Prostate glandular cells': '-0.162', 'Prostate basal glandular cells': '0.286', 'Urothelial cells': '0.283', 'Keratinocyte (other)': '0.121', 'Keratinocyte (granular)': '-0.008', 'Hair cortex cells': '-0.113', 'Inner root sheath cells': '-0.069', 'Outer root sheath cells': '0.125', 'Sebaceous gland cells': '0.110', 'Eccrine sweat gland cells': '0.070', 'Adipocytes (Skin)': '0.019', 'Mitotic cells (Skin)': '0.236', 'Parietal cells': '-0.609', 'Chief cells': '-0.599', 'Gastric mucous cells': '-0.193', 'Gastric enteroendocrine cells': '-0.441', 'Mitotic cells (Stomach)': '0.261', 'Parafollicular cells': '-0.028', 'Thyroid glandular cells': '0.094', 'Mitotic cells (Thyroid)': '0.242', 'Adrenal cortex cells': '0.619', 'Adrenal medulla cells': '0.063', 'Mitotic cells (Adrenal gland)': '0.483', 'Minor salivary glandular cells': '0.582', 'Minor salivary gland ductal cells': '0.072', 'Minor salivary gland basal cells': '0.229', 'Mitotic cells (Minor salivary gland)': '0.376', 'Adipocytes (Minor salivary gland)': '0.211', 'Somatotropes': '-0.121', 'Lactotropes': '-0.287', 'Gonadotropes': '0.004', 'Corticotropes': '-0.352', 'Thyrotropes': '-0.054', 'Undifferentiated cells (Pituitary gland)': '0.486', 'Mitotic cells (Spleen)': '-0.016', 'Platelets': '0.115', 'Erythrocytes': '0.098', 'Hematopoietic stem cells': '0.042', 'B-cells (Spleen)': '0.028', 'NK-cells (Spleen)': '0.157', 'Amygdala excitatory': '0.1', 'Cerebellar inhibitory': '0.2', 'Cge interneuron': '0.3', 'Deep-layer corticothalamic and 6b': '0.3', 'Deep-layer intratelencephalic': '0.1', 'Deep-layer near-projecting': '0.1', 'Eccentric medium spiny neuron': '0.4', 'Hippocampal ca1-3': '0.5', 'Hippocampal ca4': '0.1', 'Hippocampal dentate gyrus': '0.3', 'Lamp5-lhx6 and chandelier': '0.3', 'Lower rhombic lip': '0.2', 'Mammillary body': '0.4', 'Medium spiny neuron': '0.6', 'Mge interneuron': '0.1', 'Midbrain-derived inhibitory': '0.6', 'Miscellaneous': '0.6', 'Splatter': '0.5', 'Thalamic excitatory': '1.3', 'Upper rhombic lip': '0.1', 'Upper-layer intratelencephalic': '0.1', 'Astrocyte': '1.5', 'Bergmann glia': '1.5', 'Central nervous system macrophage': '6.0', 'Choroid plexus epithelial cell': '2.9', 'Committed oligodendrocyte precursor': '1.0', 'Ependymal cell': '1.3', 'Oligodendrocyte': '0.1', 'Oligodendrocyte precursor cell': '2.3', 'Endothelial cell': '6.4', 'Pericyte': '5.3', 'Vascular associated smooth muscle cell': '3.1', 'Fibroblast': '5.3', 'Leukocyte': '7.4', 'Basophil': '107.0', 'Eosinophil': '312.5', 'Neutrophil': '496.9', 'Classical monocyte': '25.8', 'Non-classical monocyte': '66.1', 'Intermediate monocyte': '117.0', 'T-reg': '72.1', 'GdT-cell': '89.5', 'MAIT T-cell': '61.2', 'Memory CD4 T-cell': '76.8', 'Naive CD4 T-cell': '47.0', 'Memory CD8 T-cell': '81.1', 'Naive CD8 T-cell': '43.5', 'Memory B-cell': '50.4', 'Naive B-cell': '38.5', 'Plasmacytoid DC': '47.5', 'Myeloid DC': '92.2', 'NK-cell': '88.9', 'Total PBMC': '83.8', 'Vd2 gdTCR': '67.8', 'Memory CD4 T-cell Th1\\/Th17': '48.0', 'Memory CD4 T-cell Th17': '54.6', 'Memory CD4 T-cell Th2': '54.8', 'Non-Vd2 gdTCR': '73.7', 'Memory CD4 T-cell Th1': '58.8', 'Memory CD4 T-cell TFH': '61.9', 'Terminal effector memory CD4 T-cell': '72.8', 'Central memory CD8 T-cell': '59.9', 'Effector memory CD8 T-cell': '90.7', 'Terminal effector memory CD8 T-cell': '75.8', 'Non-switched memory B-cell': '52.6', 'Plasmablast': '62.3', 'Switched memory B-cell': '55.8', 'Exhausted memory B-cell': '52.1', 'Progenitor cell': '44.7', 'Memory T-reg': '82.4', 'Naive CD4 T-cell activated': '133.9', 'Naive CD8 T-cell activated': '163.4', 'Naive T-reg': '54.7'} | 2IWG, 5JPX, 5OLM, 6FGA, 6S53, 7BBD, 8A58 | {'Adipose Tissue': 21.42795099667774, 'Adrenal Gland': 16.707763565891472, 'Bladder': 21.861904761904764, 'Blood': 61.11958557588805, 'Blood Vessel': 22.62928389513109, 'Brain': 4.305000416351249, 'Breast': 20.001740740740743, 'Cervix Uteri': 26.420526315789473, 'Colon': 23.40817458279846, 'Esophagus': 21.74157577854671, 'Fallopian Tube': 25.39, 'Heart': 6.66628106852497, 'Kidney': 13.61479775280899, 'Liver': 10.388, 'Lung': 32.00464878892734, 'Muscle': 3.944284806973848, 'Nerve': 25.39305008077545, 'Ovary': 30.51811111111111, 'Pancreas': 6.808080182926829, 'Pituitary': 12.995699646643107, 'Prostate': 21.00597551020408, 'Salivary Gland': 16.434148148148147, 'Skin': 17.851811498065228, 'Small Intestine': 28.907085561497325, 'Spleen': 50.16024896265561, 'Stomach': 19.072721448467966, 'Testis': 6.377013850415512, 'Thyroid': 21.553307810107196, 'Uterus': 29.83549295774648, 'Vagina': 21.551141025641027} | IFI16 | MGKKYKNIVLLKGLEVINDYHFRMVKSLLSNDLKLNLKMREEYDKIQIADLMEEKFRGDAGLGKLIKIFEDIPTLEDLAETLKKEKLKVKGPALSRKRKKEVDATSPAPSTSSTVKTEGAEATPGAQKRKKSTKEKAGPKGSKVSEEQTQPPSPAGAGMSTAMGRSPSPKTSLSAPPNSSSTENPKTVAKCQVTPRRNVLQKRPVIVKVLSTTKPFEYETPEMEKKIMFHATVATQTQFFHVKVLNTSLKEKFNGKKIIIISDYLEYDSLLEVNEESTVSEAGPNQTFEVPNKIINRAKETLKIDILHKQASGNIVYGVFMLHKKTVNQKTTIYEIQDDRGKMDVVGTGQCHNIPCEEGDKLQLFCFRLRKKNQMSKLISEMHSFIQIKKKTNPRNNDPKSMKLPQEQRQLPYPSEASTTFPESHLRTPQMPPTTPSSSFFTKKSEDTISKMNDFMRMQILKEGSHFPGPFMTSIGPAESHPHTPQMPPSTPSSSFLTTKSEDTISKMNDFMRMQILKEGSHFPGPFMTSIGPAESHPHTPQMPPSTPSSSFLTTLKPRLKTEPEEVSIEDSAQSDLKEVMVLNATESFVYEPKEQKKMFHATVATENEVFRVKVFNIDLKEKFTPKKIIAIANYVCRNGFLEVYPFTLVADVNADRNMEIPKGLIRSASVTPKINQLCSQTKGSFVNGVFEVHKKNVRGEFTYYEIQDNTGKMEVVVHGRLTTINCEEGDKLKLTCFELAPKSGNTGELRSVIHSHIKVIKTRKNKKDILNPDSSMETSPDFFF | Homo sapiens | Nucleus, Cytoplasm, Cytoplasm | Low tissue specificity | {'Ciliated cells': '62.3', 'Basal respiratory cells': '190.0', 'Club cells': '105.3', 'Ionocytes': '97.9', 'Mucus glandular cells': '109.7', 'Serous glandular cells': '43.7', 'Gastric mucus-secreting cells': '6.5', 'Proximal enterocytes': '8.0', 'Paneth cells': '17.2', 'Distal enterocytes': '5.5', 'Intestinal goblet cells': '19.5', 'Exocrine glandular cells': '-0.567', 'Basal prostatic cells': '38.6', 'Prostatic glandular cells': '4.9', 'Breast glandular cells': '0.150', 'Breast myoepithelial cells': '0.244', 'Glandular and luminal cells': '69.6', 'Secretory cells': '180.9', 'Basal keratinocytes': '118.1', 'Suprabasal keratinocytes': '51.4', 'Basal squamous epithelial cells': '150.7', 'Squamous epithelial cells': '74.0', 'Alveolar cells type 1': '-0.040', 'Alveolar cells type 2': '-0.465', 'Salivary duct cells': '178.3', 'Ductal cells': '0.688', 'Hepatocytes': '0.174', 'Cholangiocytes': '43.9', 'Proximal tubular cells': '0.010', 'Distal tubular cells': '0.0', 'Collecting duct cells': '48.6', 'Mesothelial cells': '0.131', 'Sertoli cells': '0.501', 'Granulosa cells': '205.1', 'Enteroendocrine cells': '18.9', 'Pancreatic endocrine cells': '57.7', 'Leydig cells': '0.644', 'Excitatory neurons': '1.2', 'Inhibitory neurons': '2.1', 'Cone photoreceptor cells': '6.8', 'Rod photoreceptor cells': '0.4', 'Bipolar cells': '0.5', 'Horizontal cells': '0.0', 'Astrocytes': '4.0', 'Oligodendrocyte precursor cells': '34.9', 'Oligodendrocytes': '19.3', 'Microglial cells': '110.9', 'Muller glia cells': '36.1', 'Schwann cells': '0.137', 'Spermatogonia': '0.442', 'Spermatocytes': '0.022', 'Early spermatids': '-0.589', 'Late spermatids': '-0.668', 'Oocytes': '12.5', 'Cytotrophoblasts': '2.8', 'Syncytiotrophoblasts': '2.5', 'Extravillous trophoblasts': '2.3', 'Endothelial cells': '293.8', 'Lymphatic endothelial cells': '179.8', 'Cardiomyocytes': '0.103', 'Skeletal myocytes': '-0.068', 'Smooth muscle cells': '140.2', 'Adipocytes': '366.4', 'Melanocytes': '0.168', 'Fibroblasts': '180.1', 'Peritubular cells': '0.458', 'Endometrial stromal cells': '222.3', 'Ovarian stromal cells': '153.0', 'Undifferentiated cells': '27.8', 'T-cells': '206.9', 'B-cells': '237.2', 'Plasma cells': '115.9', 'Nk-cells': '393.4', 'Granulocytes': '155.9', 'Monocytes': '142.7', 'Macrophages': '196.4', 'Hofbauer cells': '227.2', 'Kupffer cells': '144.9', 'Dendritic cells': '139.1', 'Langerhans cells': '0.273', 'Erythroid cells': '0.060', 'Adipocytes (Subcutaneous)': '-0.530', 'Adipocytes (Visceral)': '-0.409', 'Breast glandular cells (progenitors)': '-0.027', 'Adipocytes (Breast)': '-0.374', 'Colon enterocytes': '-0.122', 'Colon enteroendocrine cells': '0.231', 'Enteric glia cells': '0.278', 'Mitotic cells (Colon)': '0.159', 'Mitotic cells (Heart)': '0.379', 'Podocytes': '-0.048', 'Ascending Loop of Henle cells': '0.201', 'Intercalated cells': '-0.174', 'Cholangiocyte': '0.546', 'NK-cells (Liver)': '-0.092', 'Respiratory ciliated cells': '-0.061', 'Mitotic cells (Lung)': '-0.044', 'NK-cells (Lung)': '0.444', 'B-cells (Lung)': '0.264', 'Alpha cells': '0.339', 'Beta cells': '0.156', 'Prostate glandular cells': '-0.523', 'Prostate basal glandular cells': '0.118', 'Urothelial cells': '0.421', 'Keratinocyte (other)': '0.123', 'Keratinocyte (granular)': '-0.187', 'Hair cortex cells': '-0.057', 'Inner root sheath cells': '-0.003', 'Outer root sheath cells': '0.105', 'Sebaceous gland cells': '-0.041', 'Eccrine sweat gland cells': '0.035', 'Adipocytes (Skin)': '0.024', 'Mitotic cells (Skin)': '0.243', 'Parietal cells': '-0.751', 'Chief cells': '-0.642', 'Gastric mucous cells': '-0.477', 'Gastric enteroendocrine cells': '-0.420', 'Mitotic cells (Stomach)': '-0.035', 'Parafollicular cells': '-0.087', 'Thyroid glandular cells': '-0.148', 'Mitotic cells (Thyroid)': '0.311', 'Adrenal cortex cells': '0.371', 'Adrenal medulla cells': '0.065', 'Mitotic cells (Adrenal gland)': '0.334', 'Minor salivary glandular cells': '0.655', 'Minor salivary gland ductal cells': '0.003', 'Minor salivary gland basal cells': '0.344', 'Mitotic cells (Minor salivary gland)': '0.478', 'Adipocytes (Minor salivary gland)': '0.251', 'Somatotropes': '-0.259', 'Lactotropes': '-0.440', 'Gonadotropes': '-0.140', 'Corticotropes': '-0.276', 'Thyrotropes': '-0.166', 'Undifferentiated cells (Pituitary gland)': '0.394', 'Mitotic cells (Spleen)': '-0.163', 'Platelets': '-0.180', 'Erythrocytes': '-0.152', 'Hematopoietic stem cells': '-0.246', 'B-cells (Spleen)': '0.423', 'NK-cells (Spleen)': '0.283', 'Amygdala excitatory': '5.5', 'Cerebellar inhibitory': '3.0', 'Cge interneuron': '9.5', 'Deep-layer corticothalamic and 6b': '2.5', 'Deep-layer intratelencephalic': '7.2', 'Deep-layer near-projecting': '6.6', 'Eccentric medium spiny neuron': '2.4', 'Hippocampal ca1-3': '10.6', 'Hippocampal ca4': '18.5', 'Hippocampal dentate gyrus': '15.1', 'Lamp5-lhx6 and chandelier': '1.3', 'Lower rhombic lip': '0.6', 'Mammillary body': '0.3', 'Medium spiny neuron': '0.7', 'Mge interneuron': '2.7', 'Midbrain-derived inhibitory': '3.3', 'Miscellaneous': '4.9', 'Splatter': '2.3', 'Thalamic excitatory': '0.5', 'Upper rhombic lip': '0.4', 'Upper-layer intratelencephalic': '3.1', 'Astrocyte': '37.2', 'Bergmann glia': '108.6', 'Central nervous system macrophage': '504.5', 'Choroid plexus epithelial cell': '5.6', 'Committed oligodendrocyte precursor': '16.0', 'Ependymal cell': '3.6', 'Oligodendrocyte': '31.0', 'Oligodendrocyte precursor cell': '61.4', 'Endothelial cell': '198.1', 'Pericyte': '74.7', 'Vascular associated smooth muscle cell': '71.2', 'Fibroblast': '84.9', 'Leukocyte': '347.8', 'Basophil': '35.3', 'Eosinophil': '0.4', 'Neutrophil': '1177.0', 'Classical monocyte': '101.9', 'Non-classical monocyte': '124.4', 'Intermediate monocyte': '301.7', 'T-reg': '228.2', 'GdT-cell': '57.5', 'MAIT T-cell': '172.9', 'Memory CD4 T-cell': '54.4', 'Naive CD4 T-cell': '100.4', 'Memory CD8 T-cell': '59.2', 'Naive CD8 T-cell': '67.6', 'Memory B-cell': '88.7', 'Naive B-cell': '210.3', 'Plasmacytoid DC': '349.7', 'Myeloid DC': '346.0', 'NK-cell': '265.6', 'Total PBMC': '247.0', 'Vd2 gdTCR': '206.8', 'Memory CD4 T-cell TFH': '145.4', 'Memory CD4 T-cell Th2': '145.8', 'Memory CD4 T-cell Th17': '138.0', 'Memory CD4 T-cell Th1\\/Th17': '152.0', 'Non-Vd2 gdTCR': '232.8', 'Memory CD4 T-cell Th1': '153.8', 'Terminal effector memory CD4 T-cell': '245.0', 'Central memory CD8 T-cell': '172.0', 'Effector memory CD8 T-cell': '286.1', 'Terminal effector memory CD8 T-cell': '241.4', 'Switched memory B-cell': '288.2', 'Plasmablast': '304.0', 'Non-switched memory B-cell': '275.4', 'Exhausted memory B-cell': '255.0', 'Progenitor cell': '172.3', 'Naive CD4 T-cell activated': '228.9', 'Naive CD8 T-cell activated': '189.7', 'Memory T-reg': '162.3', 'Naive T-reg': '162.9'} | 2OQ0, 3B6Y, 3RLN, 3RLO, 3RNU, 4QGU, 8X70 | {'Adipose Tissue': 125.56371262458472, 'Adrenal Gland': 45.70423255813953, 'Bladder': 63.83904761904761, 'Blood': 127.25510226049516, 'Blood Vessel': 71.97602996254682, 'Brain': 9.985799394398184, 'Breast': 99.8920697167756, 'Cervix Uteri': 91.98, 'Colon': 46.42050577663672, 'Esophagus': 58.1218615916955, 'Fallopian Tube': 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0.580115 | 824 |
P19474 | Q2F514 | 34097931 | UbiBrowser | TRIM21 | MASAARLTMMWEEVTCPICLDPFVEPVSIECGHSFCQECISQVGKGGGSVCPVCRQRFLLKNLRPNRQLANMVNNLKEISQEAREGTQGERCAVHGERLHLFCEKDGKALCWVCAQSRKHRDHAMVPLEEAAQEYQEKLQVALGELRRKQELAEKLEVEIAIKRADWKKTVETQKSRIHAEFVQQKNFLVEEEQRQLQELEKDEREQLRILGEKEAKLAQQSQALQELISELDRRCHSSALELLQEVIIVLERSESWNLKDLDITSPELRSVCHVPGLKKMLRTCAVHITLDPDTANPWLILSEDRRQVRLGDTQQSIPGNEERFDSYPMVLGAQHFHSGKHYWEVDVTGKEAWDLGVCRDSVRRKGHFLLSSKSGFWTIWLWNKQKYEAGTYPQTPLHLQVPPCQVGIFLDYEAGMVSFYNITDHGSLIYSFSECAFTGPLRPFFSPGFNDGGKNTAPLTLCPLNIGSQGSTDY | Homo sapiens | Cytoplasm, Cytoplasmic vesicle, autophagosome, Nucleus, Cytoplasm, P-body, Cytoplasm, Stress granule | Low tissue specificity | {'Ciliated cells': '3.8', 'Basal respiratory cells': '6.8', 'Club cells': '5.8', 'Ionocytes': '3.7', 'Mucus glandular cells': '4.8', 'Serous glandular cells': '2.3', 'Gastric mucus-secreting cells': '8.8', 'Proximal enterocytes': '8.9', 'Paneth cells': '3.9', 'Distal enterocytes': '8.5', 'Intestinal goblet cells': '8.4', 'Exocrine glandular cells': '-0.716', 'Basal prostatic cells': '5.4', 'Prostatic glandular cells': '5.0', 'Breast glandular cells': '0.298', 'Breast myoepithelial cells': '0.351', 'Glandular and luminal cells': '5.9', 'Secretory cells': '8.4', 'Basal keratinocytes': '3.2', 'Suprabasal keratinocytes': '2.7', 'Basal squamous epithelial cells': '6.4', 'Squamous epithelial cells': '4.3', 'Alveolar cells type 1': '0.116', 'Alveolar cells type 2': '0.115', 'Salivary duct cells': '3.0', 'Ductal cells': '0.700', 'Hepatocytes': '0.503', 'Cholangiocytes': '11.4', 'Proximal tubular cells': '0.175', 'Distal tubular cells': '0.0', 'Collecting duct cells': '5.8', 'Mesothelial cells': '0.451', 'Sertoli cells': '0.479', 'Granulosa cells': '4.8', 'Enteroendocrine cells': '3.7', 'Pancreatic endocrine cells': '3.4', 'Leydig cells': '0.632', 'Excitatory neurons': '0.2', 'Inhibitory neurons': '0.1', 'Cone photoreceptor cells': '0.0', 'Rod photoreceptor cells': '0.0', 'Bipolar cells': '0.7', 'Horizontal cells': '0.6', 'Astrocytes': '0.0', 'Oligodendrocyte precursor cells': '0.9', 'Oligodendrocytes': '0.1', 'Microglial cells': '1.8', 'Muller glia cells': '2.4', 'Schwann cells': '0.099', 'Spermatogonia': '0.401', 'Spermatocytes': '-0.062', 'Early spermatids': '-0.578', 'Late spermatids': '-0.618', 'Oocytes': '1.5', 'Cytotrophoblasts': '6.6', 'Syncytiotrophoblasts': '9.8', 'Extravillous trophoblasts': '10.0', 'Endothelial cells': '7.8', 'Lymphatic endothelial cells': '6.9', 'Cardiomyocytes': '0.335', 'Skeletal myocytes': '-0.080', 'Smooth muscle cells': '6.3', 'Adipocytes': '8.3', 'Melanocytes': '0.101', 'Fibroblasts': '6.5', 'Peritubular cells': '0.579', 'Endometrial stromal cells': '4.5', 'Ovarian stromal cells': '6.7', 'Undifferentiated cells': '5.9', 'T-cells': '9.9', 'B-cells': '8.8', 'Plasma cells': '5.0', 'Nk-cells': '15.1', 'Granulocytes': '6.2', 'Monocytes': '7.8', 'Macrophages': '8.5', 'Hofbauer cells': '9.9', 'Kupffer cells': '10.3', 'Dendritic cells': '8.0', 'Langerhans cells': '0.466', 'Erythroid cells': '-0.084', 'Adipocytes (Subcutaneous)': '-0.368', 'Adipocytes (Visceral)': '-0.167', 'Breast glandular cells (progenitors)': '0.190', 'Adipocytes (Breast)': '-0.382', 'Colon enterocytes': '0.004', 'Colon enteroendocrine cells': '0.196', 'Enteric glia cells': '-0.129', 'Mitotic cells (Colon)': '0.005', 'Mitotic cells (Heart)': '0.486', 'Podocytes': '-0.114', 'Ascending Loop of Henle cells': '0.371', 'Intercalated cells': '-0.097', 'Cholangiocyte': '0.375', 'NK-cells (Liver)': '-0.278', 'Respiratory ciliated cells': '-0.022', 'Mitotic cells (Lung)': '0.157', 'NK-cells (Lung)': '0.110', 'B-cells (Lung)': '-0.155', 'Alpha cells': '0.333', 'Beta cells': '0.161', 'Prostate glandular cells': '-0.162', 'Prostate basal glandular cells': '0.286', 'Urothelial cells': '0.283', 'Keratinocyte (other)': '0.121', 'Keratinocyte (granular)': '-0.008', 'Hair cortex cells': '-0.113', 'Inner root sheath cells': '-0.069', 'Outer root sheath cells': '0.125', 'Sebaceous gland cells': '0.110', 'Eccrine sweat gland cells': '0.070', 'Adipocytes (Skin)': '0.019', 'Mitotic cells (Skin)': '0.236', 'Parietal cells': '-0.609', 'Chief cells': '-0.599', 'Gastric mucous cells': '-0.193', 'Gastric enteroendocrine cells': '-0.441', 'Mitotic cells (Stomach)': '0.261', 'Parafollicular cells': '-0.028', 'Thyroid glandular cells': '0.094', 'Mitotic cells (Thyroid)': '0.242', 'Adrenal cortex cells': '0.619', 'Adrenal medulla cells': '0.063', 'Mitotic cells (Adrenal gland)': '0.483', 'Minor salivary glandular cells': '0.582', 'Minor salivary gland ductal cells': '0.072', 'Minor salivary gland basal cells': '0.229', 'Mitotic cells (Minor salivary gland)': '0.376', 'Adipocytes (Minor salivary gland)': '0.211', 'Somatotropes': '-0.121', 'Lactotropes': '-0.287', 'Gonadotropes': '0.004', 'Corticotropes': '-0.352', 'Thyrotropes': '-0.054', 'Undifferentiated cells (Pituitary gland)': '0.486', 'Mitotic cells (Spleen)': '-0.016', 'Platelets': '0.115', 'Erythrocytes': '0.098', 'Hematopoietic stem cells': '0.042', 'B-cells (Spleen)': '0.028', 'NK-cells (Spleen)': '0.157', 'Amygdala excitatory': '0.1', 'Cerebellar inhibitory': '0.2', 'Cge interneuron': '0.3', 'Deep-layer corticothalamic and 6b': '0.3', 'Deep-layer intratelencephalic': '0.1', 'Deep-layer near-projecting': '0.1', 'Eccentric medium spiny neuron': '0.4', 'Hippocampal ca1-3': '0.5', 'Hippocampal ca4': '0.1', 'Hippocampal dentate gyrus': '0.3', 'Lamp5-lhx6 and chandelier': '0.3', 'Lower rhombic lip': '0.2', 'Mammillary body': '0.4', 'Medium spiny neuron': '0.6', 'Mge interneuron': '0.1', 'Midbrain-derived inhibitory': '0.6', 'Miscellaneous': '0.6', 'Splatter': '0.5', 'Thalamic excitatory': '1.3', 'Upper rhombic lip': '0.1', 'Upper-layer intratelencephalic': '0.1', 'Astrocyte': '1.5', 'Bergmann glia': '1.5', 'Central nervous system macrophage': '6.0', 'Choroid plexus epithelial cell': '2.9', 'Committed oligodendrocyte precursor': '1.0', 'Ependymal cell': '1.3', 'Oligodendrocyte': '0.1', 'Oligodendrocyte precursor cell': '2.3', 'Endothelial cell': '6.4', 'Pericyte': '5.3', 'Vascular associated smooth muscle cell': '3.1', 'Fibroblast': '5.3', 'Leukocyte': '7.4', 'Basophil': '107.0', 'Eosinophil': '312.5', 'Neutrophil': '496.9', 'Classical monocyte': '25.8', 'Non-classical monocyte': '66.1', 'Intermediate monocyte': '117.0', 'T-reg': '72.1', 'GdT-cell': '89.5', 'MAIT T-cell': '61.2', 'Memory CD4 T-cell': '76.8', 'Naive CD4 T-cell': '47.0', 'Memory CD8 T-cell': '81.1', 'Naive CD8 T-cell': '43.5', 'Memory B-cell': '50.4', 'Naive B-cell': '38.5', 'Plasmacytoid DC': '47.5', 'Myeloid DC': '92.2', 'NK-cell': '88.9', 'Total PBMC': '83.8', 'Vd2 gdTCR': '67.8', 'Memory CD4 T-cell Th1\\/Th17': '48.0', 'Memory CD4 T-cell Th17': '54.6', 'Memory CD4 T-cell Th2': '54.8', 'Non-Vd2 gdTCR': '73.7', 'Memory CD4 T-cell Th1': '58.8', 'Memory CD4 T-cell TFH': '61.9', 'Terminal effector memory CD4 T-cell': '72.8', 'Central memory CD8 T-cell': '59.9', 'Effector memory CD8 T-cell': '90.7', 'Terminal effector memory CD8 T-cell': '75.8', 'Non-switched memory B-cell': '52.6', 'Plasmablast': '62.3', 'Switched memory B-cell': '55.8', 'Exhausted memory B-cell': '52.1', 'Progenitor cell': '44.7', 'Memory T-reg': '82.4', 'Naive CD4 T-cell activated': '133.9', 'Naive CD8 T-cell activated': '163.4', 'Naive T-reg': '54.7'} | 2IWG, 5JPX, 5OLM, 6FGA, 6S53, 7BBD, 8A58 | {'Adipose Tissue': 21.42795099667774, 'Adrenal Gland': 16.707763565891472, 'Bladder': 21.861904761904764, 'Blood': 61.11958557588805, 'Blood Vessel': 22.62928389513109, 'Brain': 4.305000416351249, 'Breast': 20.001740740740743, 'Cervix Uteri': 26.420526315789473, 'Colon': 23.40817458279846, 'Esophagus': 21.74157577854671, 'Fallopian Tube': 25.39, 'Heart': 6.66628106852497, 'Kidney': 13.61479775280899, 'Liver': 10.388, 'Lung': 32.00464878892734, 'Muscle': 3.944284806973848, 'Nerve': 25.39305008077545, 'Ovary': 30.51811111111111, 'Pancreas': 6.808080182926829, 'Pituitary': 12.995699646643107, 'Prostate': 21.00597551020408, 'Salivary Gland': 16.434148148148147, 'Skin': 17.851811498065228, 'Small Intestine': 28.907085561497325, 'Spleen': 50.16024896265561, 'Stomach': 19.072721448467966, 'Testis': 6.377013850415512, 'Thyroid': 21.553307810107196, 'Uterus': 29.83549295774648, 'Vagina': 21.551141025641027} | X | MAARLCCQLDPARDVLCLRPVGAESCGRPFSGSLGTLSSPSPSAVPTDHGAHLSLRGLPVCAFSSAGPCALRFTSARRMETTVNAHQILPKVLHKRTLGLSAMSTTDLEAYFKDCLFKDWEELGEEIRLKVFVLGGCRHKLVCAPAPCNFFTSA | Hepatitis B virus | Host cytoplasm, Host nucleus, Host mitochondrion | Not found | {} | null | {} | [37.42, 45.2, 56.71, 57.57, 65.92, 71.8, 70.72, 70.19, 75.03, 81.06, 81.95, 82.13, 85.0, 89.84, 89.65, 93.29, 90.82, 89.33, 90.46, 84.59, 85.8, 87.81, 91.19, 89.54, 92.34, 94.82, 95.66, 94.94, 93.26, 90.29, 93.55, 91.65, 95.23, 95.54, 95.57, 95.25, 94.22, 93.77, 94.59, 93.99, 92.38, 92.01, 90.02, 87.48, 84.99, 84.15, 85.0, 86.86, 92.88, 92.09, 93.98, 92.61, 92.26, 94.16, 91.11, 93.0, 91.84, 92.37, 91.85, 87.92, 88.9, 90.86, 91.4, 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UBE2E1, UBE2E2 | Homotrimer | null | 90.718042 | 0.406716 | null | null | 2,875 |
P19474 | Q92985 | 21183682 | UbiNet, UbiBrowser | TRIM21 | MASAARLTMMWEEVTCPICLDPFVEPVSIECGHSFCQECISQVGKGGGSVCPVCRQRFLLKNLRPNRQLANMVNNLKEISQEAREGTQGERCAVHGERLHLFCEKDGKALCWVCAQSRKHRDHAMVPLEEAAQEYQEKLQVALGELRRKQELAEKLEVEIAIKRADWKKTVETQKSRIHAEFVQQKNFLVEEEQRQLQELEKDEREQLRILGEKEAKLAQQSQALQELISELDRRCHSSALELLQEVIIVLERSESWNLKDLDITSPELRSVCHVPGLKKMLRTCAVHITLDPDTANPWLILSEDRRQVRLGDTQQSIPGNEERFDSYPMVLGAQHFHSGKHYWEVDVTGKEAWDLGVCRDSVRRKGHFLLSSKSGFWTIWLWNKQKYEAGTYPQTPLHLQVPPCQVGIFLDYEAGMVSFYNITDHGSLIYSFSECAFTGPLRPFFSPGFNDGGKNTAPLTLCPLNIGSQGSTDY | Homo sapiens | Cytoplasm, Cytoplasmic vesicle, autophagosome, Nucleus, Cytoplasm, P-body, Cytoplasm, Stress granule | Low tissue specificity | {'Ciliated cells': '3.8', 'Basal respiratory cells': '6.8', 'Club cells': '5.8', 'Ionocytes': '3.7', 'Mucus glandular cells': '4.8', 'Serous glandular cells': '2.3', 'Gastric mucus-secreting cells': '8.8', 'Proximal enterocytes': '8.9', 'Paneth cells': '3.9', 'Distal enterocytes': '8.5', 'Intestinal goblet cells': '8.4', 'Exocrine glandular cells': '-0.716', 'Basal prostatic cells': '5.4', 'Prostatic glandular cells': '5.0', 'Breast glandular cells': '0.298', 'Breast myoepithelial cells': '0.351', 'Glandular and luminal cells': '5.9', 'Secretory cells': '8.4', 'Basal keratinocytes': '3.2', 'Suprabasal keratinocytes': '2.7', 'Basal squamous epithelial cells': '6.4', 'Squamous epithelial cells': '4.3', 'Alveolar cells type 1': '0.116', 'Alveolar cells type 2': '0.115', 'Salivary duct cells': '3.0', 'Ductal cells': '0.700', 'Hepatocytes': '0.503', 'Cholangiocytes': '11.4', 'Proximal tubular cells': '0.175', 'Distal tubular cells': '0.0', 'Collecting duct cells': '5.8', 'Mesothelial cells': '0.451', 'Sertoli cells': '0.479', 'Granulosa cells': '4.8', 'Enteroendocrine cells': '3.7', 'Pancreatic endocrine cells': '3.4', 'Leydig cells': '0.632', 'Excitatory neurons': '0.2', 'Inhibitory neurons': '0.1', 'Cone photoreceptor cells': '0.0', 'Rod photoreceptor cells': '0.0', 'Bipolar cells': '0.7', 'Horizontal cells': '0.6', 'Astrocytes': '0.0', 'Oligodendrocyte precursor cells': '0.9', 'Oligodendrocytes': '0.1', 'Microglial cells': '1.8', 'Muller glia cells': '2.4', 'Schwann cells': '0.099', 'Spermatogonia': '0.401', 'Spermatocytes': '-0.062', 'Early spermatids': '-0.578', 'Late spermatids': '-0.618', 'Oocytes': '1.5', 'Cytotrophoblasts': '6.6', 'Syncytiotrophoblasts': '9.8', 'Extravillous trophoblasts': '10.0', 'Endothelial cells': '7.8', 'Lymphatic endothelial cells': '6.9', 'Cardiomyocytes': '0.335', 'Skeletal myocytes': '-0.080', 'Smooth muscle cells': '6.3', 'Adipocytes': '8.3', 'Melanocytes': '0.101', 'Fibroblasts': '6.5', 'Peritubular cells': '0.579', 'Endometrial stromal cells': '4.5', 'Ovarian stromal cells': '6.7', 'Undifferentiated cells': '5.9', 'T-cells': '9.9', 'B-cells': '8.8', 'Plasma cells': '5.0', 'Nk-cells': '15.1', 'Granulocytes': '6.2', 'Monocytes': '7.8', 'Macrophages': '8.5', 'Hofbauer cells': '9.9', 'Kupffer cells': '10.3', 'Dendritic cells': '8.0', 'Langerhans cells': '0.466', 'Erythroid cells': '-0.084', 'Adipocytes (Subcutaneous)': '-0.368', 'Adipocytes (Visceral)': '-0.167', 'Breast glandular cells (progenitors)': '0.190', 'Adipocytes (Breast)': '-0.382', 'Colon enterocytes': '0.004', 'Colon enteroendocrine cells': '0.196', 'Enteric glia cells': '-0.129', 'Mitotic cells (Colon)': '0.005', 'Mitotic cells (Heart)': '0.486', 'Podocytes': '-0.114', 'Ascending Loop of Henle cells': '0.371', 'Intercalated cells': '-0.097', 'Cholangiocyte': '0.375', 'NK-cells (Liver)': '-0.278', 'Respiratory ciliated cells': '-0.022', 'Mitotic cells (Lung)': '0.157', 'NK-cells (Lung)': '0.110', 'B-cells (Lung)': '-0.155', 'Alpha cells': '0.333', 'Beta cells': '0.161', 'Prostate glandular cells': '-0.162', 'Prostate basal glandular cells': '0.286', 'Urothelial cells': '0.283', 'Keratinocyte (other)': '0.121', 'Keratinocyte (granular)': '-0.008', 'Hair cortex cells': '-0.113', 'Inner root sheath cells': '-0.069', 'Outer root sheath cells': '0.125', 'Sebaceous gland cells': '0.110', 'Eccrine sweat gland cells': '0.070', 'Adipocytes (Skin)': '0.019', 'Mitotic cells (Skin)': '0.236', 'Parietal cells': '-0.609', 'Chief cells': '-0.599', 'Gastric mucous cells': '-0.193', 'Gastric enteroendocrine cells': '-0.441', 'Mitotic cells (Stomach)': '0.261', 'Parafollicular cells': '-0.028', 'Thyroid glandular cells': '0.094', 'Mitotic cells (Thyroid)': '0.242', 'Adrenal cortex cells': '0.619', 'Adrenal medulla cells': '0.063', 'Mitotic cells (Adrenal gland)': '0.483', 'Minor salivary glandular cells': '0.582', 'Minor salivary gland ductal cells': '0.072', 'Minor salivary gland basal cells': '0.229', 'Mitotic cells (Minor salivary gland)': '0.376', 'Adipocytes (Minor salivary gland)': '0.211', 'Somatotropes': '-0.121', 'Lactotropes': '-0.287', 'Gonadotropes': '0.004', 'Corticotropes': '-0.352', 'Thyrotropes': '-0.054', 'Undifferentiated cells (Pituitary gland)': '0.486', 'Mitotic cells (Spleen)': '-0.016', 'Platelets': '0.115', 'Erythrocytes': '0.098', 'Hematopoietic stem cells': '0.042', 'B-cells (Spleen)': '0.028', 'NK-cells (Spleen)': '0.157', 'Amygdala excitatory': '0.1', 'Cerebellar inhibitory': '0.2', 'Cge interneuron': '0.3', 'Deep-layer corticothalamic and 6b': '0.3', 'Deep-layer intratelencephalic': '0.1', 'Deep-layer near-projecting': '0.1', 'Eccentric medium spiny neuron': '0.4', 'Hippocampal ca1-3': '0.5', 'Hippocampal ca4': '0.1', 'Hippocampal dentate gyrus': '0.3', 'Lamp5-lhx6 and chandelier': '0.3', 'Lower rhombic lip': '0.2', 'Mammillary body': '0.4', 'Medium spiny neuron': '0.6', 'Mge interneuron': '0.1', 'Midbrain-derived inhibitory': '0.6', 'Miscellaneous': '0.6', 'Splatter': '0.5', 'Thalamic excitatory': '1.3', 'Upper rhombic lip': '0.1', 'Upper-layer intratelencephalic': '0.1', 'Astrocyte': '1.5', 'Bergmann glia': '1.5', 'Central nervous system macrophage': '6.0', 'Choroid plexus epithelial cell': '2.9', 'Committed oligodendrocyte precursor': '1.0', 'Ependymal cell': '1.3', 'Oligodendrocyte': '0.1', 'Oligodendrocyte precursor cell': '2.3', 'Endothelial cell': '6.4', 'Pericyte': '5.3', 'Vascular associated smooth muscle cell': '3.1', 'Fibroblast': '5.3', 'Leukocyte': '7.4', 'Basophil': '107.0', 'Eosinophil': '312.5', 'Neutrophil': '496.9', 'Classical monocyte': '25.8', 'Non-classical monocyte': '66.1', 'Intermediate monocyte': '117.0', 'T-reg': '72.1', 'GdT-cell': '89.5', 'MAIT T-cell': '61.2', 'Memory CD4 T-cell': '76.8', 'Naive CD4 T-cell': '47.0', 'Memory CD8 T-cell': '81.1', 'Naive CD8 T-cell': '43.5', 'Memory B-cell': '50.4', 'Naive B-cell': '38.5', 'Plasmacytoid DC': '47.5', 'Myeloid DC': '92.2', 'NK-cell': '88.9', 'Total PBMC': '83.8', 'Vd2 gdTCR': '67.8', 'Memory CD4 T-cell Th1\\/Th17': '48.0', 'Memory CD4 T-cell Th17': '54.6', 'Memory CD4 T-cell Th2': '54.8', 'Non-Vd2 gdTCR': '73.7', 'Memory CD4 T-cell Th1': '58.8', 'Memory CD4 T-cell TFH': '61.9', 'Terminal effector memory CD4 T-cell': '72.8', 'Central memory CD8 T-cell': '59.9', 'Effector memory CD8 T-cell': '90.7', 'Terminal effector memory CD8 T-cell': '75.8', 'Non-switched memory B-cell': '52.6', 'Plasmablast': '62.3', 'Switched memory B-cell': '55.8', 'Exhausted memory B-cell': '52.1', 'Progenitor cell': '44.7', 'Memory T-reg': '82.4', 'Naive CD4 T-cell activated': '133.9', 'Naive CD8 T-cell activated': '163.4', 'Naive T-reg': '54.7'} | 2IWG, 5JPX, 5OLM, 6FGA, 6S53, 7BBD, 8A58 | {'Adipose Tissue': 21.42795099667774, 'Adrenal Gland': 16.707763565891472, 'Bladder': 21.861904761904764, 'Blood': 61.11958557588805, 'Blood Vessel': 22.62928389513109, 'Brain': 4.305000416351249, 'Breast': 20.001740740740743, 'Cervix Uteri': 26.420526315789473, 'Colon': 23.40817458279846, 'Esophagus': 21.74157577854671, 'Fallopian Tube': 25.39, 'Heart': 6.66628106852497, 'Kidney': 13.61479775280899, 'Liver': 10.388, 'Lung': 32.00464878892734, 'Muscle': 3.944284806973848, 'Nerve': 25.39305008077545, 'Ovary': 30.51811111111111, 'Pancreas': 6.808080182926829, 'Pituitary': 12.995699646643107, 'Prostate': 21.00597551020408, 'Salivary Gland': 16.434148148148147, 'Skin': 17.851811498065228, 'Small Intestine': 28.907085561497325, 'Spleen': 50.16024896265561, 'Stomach': 19.072721448467966, 'Testis': 6.377013850415512, 'Thyroid': 21.553307810107196, 'Uterus': 29.83549295774648, 'Vagina': 21.551141025641027} | IRF7 | MALAPERAAPRVLFGEWLLGEISSGCYEGLQWLDEARTCFRVPWKHFARKDLSEADARIFKAWAVARGRWPPSSRGGGPPPEAETAERAGWKTNFRCALRSTRRFVMLRDNSGDPADPHKVYALSRELCWREGPGTDQTEAEAPAAVPPPQGGPPGPFLAHTHAGLQAPGPLPAPAGDKGDLLLQAVQQSCLADHLLTASWGADPVPTKAPGEGQEGLPLTGACAGGPGLPAGELYGWAVETTPSPGPQPAALTTGEAAAPESPHQAEPYLSPSPSACTAVQEPSPGALDVTIMYKGRTVLQKVVGHPSCTFLYGPPDPAVRATDPQQVAFPSPAELPDQKQLRYTEELLRHVAPGLHLELRGPQLWARRMGKCKVYWEVGGPPGSASPSTPACLLPRNCDTPIFDFRVFFQELVEFRARQRRGSPRYTIYLGFGQDLSAGRPKEKSLVLVKLEPWLCRVHLEGTQREGVSSLDSSSLSLCLSSANSLYDDIECFLMELEQPA | Homo sapiens | Nucleus, Cytoplasm | Tissue enhanced (liver, lymphoid tissue) | {'Ciliated cells': '21.5', 'Basal respiratory cells': '19.5', 'Club cells': '21.0', 'Ionocytes': '22.1', 'Mucus glandular cells': '12.1', 'Serous glandular cells': '9.7', 'Gastric mucus-secreting cells': '40.1', 'Proximal enterocytes': '34.2', 'Paneth cells': '32.9', 'Distal enterocytes': '46.7', 'Intestinal goblet cells': '40.4', 'Exocrine glandular cells': '-0.643', 'Basal prostatic cells': '13.7', 'Prostatic glandular cells': '7.9', 'Breast glandular cells': '0.425', 'Breast myoepithelial cells': '0.420', 'Glandular and luminal cells': '20.7', 'Secretory cells': '10.2', 'Basal keratinocytes': '21.7', 'Suprabasal keratinocytes': '19.1', 'Basal squamous epithelial cells': '15.1', 'Squamous epithelial cells': '6.1', 'Alveolar cells type 1': '0.068', 'Alveolar cells type 2': '-0.492', 'Salivary duct cells': '13.3', 'Ductal cells': '0.625', 'Hepatocytes': '0.084', 'Cholangiocytes': '11.4', 'Proximal tubular cells': '0.130', 'Distal tubular cells': '9.2', 'Collecting duct cells': '21.4', 'Mesothelial cells': '0.398', 'Sertoli cells': '0.331', 'Granulosa cells': '10.1', 'Enteroendocrine cells': '20.0', 'Pancreatic endocrine cells': '30.6', 'Leydig cells': '0.431', 'Excitatory neurons': '0.0', 'Inhibitory neurons': '0.0', 'Cone photoreceptor cells': '1.7', 'Rod photoreceptor cells': '2.8', 'Bipolar cells': '0.7', 'Horizontal cells': '0.0', 'Astrocytes': '2.8', 'Oligodendrocyte precursor cells': '0.9', 'Oligodendrocytes': '1.2', 'Microglial cells': '3.6', 'Muller glia cells': '3.2', 'Schwann cells': '0.217', 'Spermatogonia': '0.210', 'Spermatocytes': '-0.275', 'Early spermatids': '-0.561', 'Late spermatids': '-0.436', 'Oocytes': '14.0', 'Cytotrophoblasts': '5.8', 'Syncytiotrophoblasts': '22.2', 'Extravillous trophoblasts': '45.4', 'Endothelial cells': '27.9', 'Lymphatic endothelial cells': '47.7', 'Cardiomyocytes': '-0.193', 'Skeletal myocytes': '-0.160', 'Smooth muscle cells': '14.7', 'Adipocytes': '57.0', 'Melanocytes': '0.066', 'Fibroblasts': '12.8', 'Peritubular cells': '0.382', 'Endometrial stromal cells': '6.1', 'Ovarian stromal cells': '10.7', 'Undifferentiated cells': '12.1', 'T-cells': '35.3', 'B-cells': '63.6', 'Plasma cells': '57.6', 'Nk-cells': '35.6', 'Granulocytes': '11.9', 'Monocytes': '136.2', 'Macrophages': '58.5', 'Hofbauer cells': '61.8', 'Kupffer cells': '21.0', 'Dendritic cells': '1058.5', 'Langerhans cells': '0.183', 'Erythroid cells': '0.086', 'Adipocytes (Subcutaneous)': '-0.467', 'Adipocytes (Visceral)': '-0.410', 'Breast glandular cells (progenitors)': '0.227', 'Adipocytes (Breast)': '-0.639', 'Colon enterocytes': '0.006', 'Colon enteroendocrine cells': '0.122', 'Enteric glia cells': '0.435', 'Mitotic cells (Colon)': '0.171', 'Mitotic cells (Heart)': '0.104', 'Podocytes': '-0.041', 'Ascending Loop of Henle cells': '0.154', 'Intercalated cells': '-0.161', 'Cholangiocyte': '0.221', 'NK-cells (Liver)': '-0.068', 'Respiratory ciliated cells': '0.072', 'Mitotic cells (Lung)': '-0.166', 'NK-cells (Lung)': '0.480', 'B-cells (Lung)': '0.226', 'Alpha cells': '0.290', 'Beta cells': '0.164', 'Prostate glandular cells': '0.210', 'Prostate basal glandular cells': '0.426', 'Urothelial cells': '0.467', 'Keratinocyte (other)': '0.295', 'Keratinocyte (granular)': '-0.066', 'Hair cortex cells': '-0.113', 'Inner root sheath cells': '-0.093', 'Outer root sheath cells': '0.103', 'Sebaceous gland cells': '-0.243', 'Eccrine sweat gland cells': '-0.108', 'Adipocytes (Skin)': '-0.337', 'Mitotic cells (Skin)': '0.140', 'Parietal cells': '-0.263', 'Chief cells': '-0.144', 'Gastric mucous cells': '0.142', 'Gastric enteroendocrine cells': '0.065', 'Mitotic cells (Stomach)': '0.150', 'Parafollicular cells': '0.004', 'Thyroid glandular cells': '-0.071', 'Mitotic cells (Thyroid)': '0.026', 'Adrenal cortex cells': '0.041', 'Adrenal medulla cells': '0.094', 'Mitotic cells (Adrenal gland)': '-0.144', 'Minor salivary glandular cells': '0.499', 'Minor salivary gland ductal cells': '0.055', 'Minor salivary gland basal cells': '0.108', 'Mitotic cells (Minor salivary gland)': '0.197', 'Adipocytes (Minor salivary gland)': '0.147', 'Somatotropes': '-0.298', 'Lactotropes': '-0.306', 'Gonadotropes': '-0.144', 'Corticotropes': '0.083', 'Thyrotropes': '-0.012', 'Undifferentiated cells (Pituitary gland)': '0.199', 'Mitotic cells (Spleen)': '-0.001', 'Platelets': '-0.107', 'Erythrocytes': '0.102', 'Hematopoietic stem cells': '-0.199', 'B-cells (Spleen)': '0.125', 'NK-cells (Spleen)': '0.195', 'Amygdala excitatory': '0.1', 'Cerebellar inhibitory': '0.3', 'Cge interneuron': '0.3', 'Deep-layer corticothalamic and 6b': '0.1', 'Deep-layer intratelencephalic': '0.1', 'Deep-layer near-projecting': '0.1', 'Eccentric medium spiny neuron': '0.1', 'Hippocampal ca1-3': '0.1', 'Hippocampal ca4': '0.8', 'Hippocampal dentate gyrus': '0.2', 'Lamp5-lhx6 and chandelier': '0.2', 'Lower rhombic lip': '0.0', 'Mammillary body': '0.1', 'Medium spiny neuron': '0.0', 'Mge interneuron': '0.1', 'Midbrain-derived inhibitory': '0.0', 'Miscellaneous': '0.0', 'Splatter': '0.4', 'Thalamic excitatory': '0.1', 'Upper rhombic lip': '2.2', 'Upper-layer intratelencephalic': '0.0', 'Astrocyte': '7.3', 'Bergmann glia': '5.0', 'Central nervous system macrophage': '19.1', 'Choroid plexus epithelial cell': '11.7', 'Committed oligodendrocyte precursor': '2.2', 'Ependymal cell': '6.0', 'Oligodendrocyte': '1.8', 'Oligodendrocyte precursor cell': '2.3', 'Endothelial cell': '34.4', 'Pericyte': '8.2', 'Vascular associated smooth muscle cell': '6.8', 'Fibroblast': '7.3', 'Leukocyte': '19.4', 'Basophil': '46.1', 'Eosinophil': '30.7', 'Neutrophil': '129.5', 'Classical monocyte': '50.9', 'Non-classical monocyte': '36.9', 'Intermediate monocyte': '87.7', 'T-reg': '23.7', 'GdT-cell': '8.1', 'MAIT T-cell': '26.5', 'Memory CD4 T-cell': '6.7', 'Naive CD4 T-cell': '11.8', 'Memory CD8 T-cell': '7.0', 'Naive CD8 T-cell': '18.1', 'Memory B-cell': '16.6', 'Naive B-cell': '13.0', 'Plasmacytoid DC': '1371.7', 'Myeloid DC': '87.9', 'NK-cell': '23.4', 'Total PBMC': '21.3', 'Vd2 gdTCR': '22.4', 'Memory CD4 T-cell TFH': '47.4', 'Memory CD4 T-cell Th2': '23.5', 'Memory CD4 T-cell Th17': '21.6', 'Memory CD4 T-cell Th1\\/Th17': '11.3', 'Non-Vd2 gdTCR': '15.6', 'Memory CD4 T-cell Th1': '25.9', 'Terminal effector memory CD4 T-cell': '1.3', 'Central memory CD8 T-cell': '19.2', 'Effector memory CD8 T-cell': '18.2', 'Terminal effector memory CD8 T-cell': '14.0', 'Switched memory B-cell': '59.3', 'Plasmablast': '124.8', 'Non-switched memory B-cell': '42.2', 'Exhausted memory B-cell': '76.1', 'Progenitor cell': '21.1', 'Naive CD4 T-cell activated': '14.9', 'Naive CD8 T-cell activated': '18.6', 'Memory T-reg': '41.0', 'Naive T-reg': '22.2'} | 2O61 | {'Adipose Tissue': 27.812443521594684, 'Adrenal Gland': 7.714255813953488, 'Bladder': 18.238095238095237, 'Blood': 116.96281270182992, 'Blood Vessel': 17.866871910112362, 'Brain': 9.179954769114309, 'Breast': 28.970784313725492, 'Cervix Uteri': 33.107894736842105, 'Colon': 20.529478818998715, 'Esophagus': 22.21950588235294, 'Fallopian Tube': 25.66311111111111, 'Heart': 10.348394889663185, 'Kidney': 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0.64, 0.94, 0.98] | RING finger | Component of a SCF(SKP2)-like complex containing CUL1, SKP1, TRIM21 and SKP2. | SCF | null | IRF8, CALR, CUL1, FBXW11, HSPA5, IKBKB, IRF3, SKP1 , VCP,SKP2, DCP2 ,ULK1, BECN1,GABARAP, GABARAPL1, GABARAPL2 , MAP1LC3C,SQSTM1,IRF3 , NMI, IFI35 , CUL1, TRIM21 | USP4, IKBKB, TRIM21, CDKN1B, IRF3, IRF8, MNI | mono, 63 | null | UBE2D2, UBE2D1, UBE2E1, UBE2E2 | Homotrimer | null | 90.718042 | 0.406716 | 68.180537 | 0.537396 | 1,575 |
P19474 | Q9C035 | 18312418, E3Net | UbiNet, UbiBrowser, 31181401 | TRIM21 | MASAARLTMMWEEVTCPICLDPFVEPVSIECGHSFCQECISQVGKGGGSVCPVCRQRFLLKNLRPNRQLANMVNNLKEISQEAREGTQGERCAVHGERLHLFCEKDGKALCWVCAQSRKHRDHAMVPLEEAAQEYQEKLQVALGELRRKQELAEKLEVEIAIKRADWKKTVETQKSRIHAEFVQQKNFLVEEEQRQLQELEKDEREQLRILGEKEAKLAQQSQALQELISELDRRCHSSALELLQEVIIVLERSESWNLKDLDITSPELRSVCHVPGLKKMLRTCAVHITLDPDTANPWLILSEDRRQVRLGDTQQSIPGNEERFDSYPMVLGAQHFHSGKHYWEVDVTGKEAWDLGVCRDSVRRKGHFLLSSKSGFWTIWLWNKQKYEAGTYPQTPLHLQVPPCQVGIFLDYEAGMVSFYNITDHGSLIYSFSECAFTGPLRPFFSPGFNDGGKNTAPLTLCPLNIGSQGSTDY | Homo sapiens | Cytoplasm, Cytoplasmic vesicle, autophagosome, Nucleus, Cytoplasm, P-body, Cytoplasm, Stress granule | Low tissue specificity | {'Ciliated cells': '3.8', 'Basal respiratory cells': '6.8', 'Club cells': '5.8', 'Ionocytes': '3.7', 'Mucus glandular cells': '4.8', 'Serous glandular cells': '2.3', 'Gastric mucus-secreting cells': '8.8', 'Proximal enterocytes': '8.9', 'Paneth cells': '3.9', 'Distal enterocytes': '8.5', 'Intestinal goblet cells': '8.4', 'Exocrine glandular cells': '-0.716', 'Basal prostatic cells': '5.4', 'Prostatic glandular cells': '5.0', 'Breast glandular cells': '0.298', 'Breast myoepithelial cells': '0.351', 'Glandular and luminal cells': '5.9', 'Secretory cells': '8.4', 'Basal keratinocytes': '3.2', 'Suprabasal keratinocytes': '2.7', 'Basal squamous epithelial cells': '6.4', 'Squamous epithelial cells': '4.3', 'Alveolar cells type 1': '0.116', 'Alveolar cells type 2': '0.115', 'Salivary duct cells': '3.0', 'Ductal cells': '0.700', 'Hepatocytes': '0.503', 'Cholangiocytes': '11.4', 'Proximal tubular cells': '0.175', 'Distal tubular cells': '0.0', 'Collecting duct cells': '5.8', 'Mesothelial cells': '0.451', 'Sertoli cells': '0.479', 'Granulosa cells': '4.8', 'Enteroendocrine cells': '3.7', 'Pancreatic endocrine cells': '3.4', 'Leydig cells': '0.632', 'Excitatory neurons': '0.2', 'Inhibitory neurons': '0.1', 'Cone photoreceptor cells': '0.0', 'Rod photoreceptor cells': '0.0', 'Bipolar cells': '0.7', 'Horizontal cells': '0.6', 'Astrocytes': '0.0', 'Oligodendrocyte precursor cells': '0.9', 'Oligodendrocytes': '0.1', 'Microglial cells': '1.8', 'Muller glia cells': '2.4', 'Schwann cells': '0.099', 'Spermatogonia': '0.401', 'Spermatocytes': '-0.062', 'Early spermatids': '-0.578', 'Late spermatids': '-0.618', 'Oocytes': '1.5', 'Cytotrophoblasts': '6.6', 'Syncytiotrophoblasts': '9.8', 'Extravillous trophoblasts': '10.0', 'Endothelial cells': '7.8', 'Lymphatic endothelial cells': '6.9', 'Cardiomyocytes': '0.335', 'Skeletal myocytes': '-0.080', 'Smooth muscle cells': '6.3', 'Adipocytes': '8.3', 'Melanocytes': '0.101', 'Fibroblasts': '6.5', 'Peritubular cells': '0.579', 'Endometrial stromal cells': '4.5', 'Ovarian stromal cells': '6.7', 'Undifferentiated cells': '5.9', 'T-cells': '9.9', 'B-cells': '8.8', 'Plasma cells': '5.0', 'Nk-cells': '15.1', 'Granulocytes': '6.2', 'Monocytes': '7.8', 'Macrophages': '8.5', 'Hofbauer cells': '9.9', 'Kupffer cells': '10.3', 'Dendritic cells': '8.0', 'Langerhans cells': '0.466', 'Erythroid cells': '-0.084', 'Adipocytes (Subcutaneous)': '-0.368', 'Adipocytes (Visceral)': '-0.167', 'Breast glandular cells (progenitors)': '0.190', 'Adipocytes (Breast)': '-0.382', 'Colon enterocytes': '0.004', 'Colon enteroendocrine cells': '0.196', 'Enteric glia cells': '-0.129', 'Mitotic cells (Colon)': '0.005', 'Mitotic cells (Heart)': '0.486', 'Podocytes': '-0.114', 'Ascending Loop of Henle cells': '0.371', 'Intercalated cells': '-0.097', 'Cholangiocyte': '0.375', 'NK-cells (Liver)': '-0.278', 'Respiratory ciliated cells': '-0.022', 'Mitotic cells (Lung)': '0.157', 'NK-cells (Lung)': '0.110', 'B-cells (Lung)': '-0.155', 'Alpha cells': '0.333', 'Beta cells': '0.161', 'Prostate glandular cells': '-0.162', 'Prostate basal glandular cells': '0.286', 'Urothelial cells': '0.283', 'Keratinocyte (other)': '0.121', 'Keratinocyte (granular)': '-0.008', 'Hair cortex cells': '-0.113', 'Inner root sheath cells': '-0.069', 'Outer root sheath cells': '0.125', 'Sebaceous gland cells': '0.110', 'Eccrine sweat gland cells': '0.070', 'Adipocytes (Skin)': '0.019', 'Mitotic cells (Skin)': '0.236', 'Parietal cells': '-0.609', 'Chief cells': '-0.599', 'Gastric mucous cells': '-0.193', 'Gastric enteroendocrine cells': '-0.441', 'Mitotic cells (Stomach)': '0.261', 'Parafollicular cells': '-0.028', 'Thyroid glandular cells': '0.094', 'Mitotic cells (Thyroid)': '0.242', 'Adrenal cortex cells': '0.619', 'Adrenal medulla cells': '0.063', 'Mitotic cells (Adrenal gland)': '0.483', 'Minor salivary glandular cells': '0.582', 'Minor salivary gland ductal cells': '0.072', 'Minor salivary gland basal cells': '0.229', 'Mitotic cells (Minor salivary gland)': '0.376', 'Adipocytes (Minor salivary gland)': '0.211', 'Somatotropes': '-0.121', 'Lactotropes': '-0.287', 'Gonadotropes': '0.004', 'Corticotropes': '-0.352', 'Thyrotropes': '-0.054', 'Undifferentiated cells (Pituitary gland)': '0.486', 'Mitotic cells (Spleen)': '-0.016', 'Platelets': '0.115', 'Erythrocytes': '0.098', 'Hematopoietic stem cells': '0.042', 'B-cells (Spleen)': '0.028', 'NK-cells (Spleen)': '0.157', 'Amygdala excitatory': '0.1', 'Cerebellar inhibitory': '0.2', 'Cge interneuron': '0.3', 'Deep-layer corticothalamic and 6b': '0.3', 'Deep-layer intratelencephalic': '0.1', 'Deep-layer near-projecting': '0.1', 'Eccentric medium spiny neuron': '0.4', 'Hippocampal ca1-3': '0.5', 'Hippocampal ca4': '0.1', 'Hippocampal dentate gyrus': '0.3', 'Lamp5-lhx6 and chandelier': '0.3', 'Lower rhombic lip': '0.2', 'Mammillary body': '0.4', 'Medium spiny neuron': '0.6', 'Mge interneuron': '0.1', 'Midbrain-derived inhibitory': '0.6', 'Miscellaneous': '0.6', 'Splatter': '0.5', 'Thalamic excitatory': '1.3', 'Upper rhombic lip': '0.1', 'Upper-layer intratelencephalic': '0.1', 'Astrocyte': '1.5', 'Bergmann glia': '1.5', 'Central nervous system macrophage': '6.0', 'Choroid plexus epithelial cell': '2.9', 'Committed oligodendrocyte precursor': '1.0', 'Ependymal cell': '1.3', 'Oligodendrocyte': '0.1', 'Oligodendrocyte precursor cell': '2.3', 'Endothelial cell': '6.4', 'Pericyte': '5.3', 'Vascular associated smooth muscle cell': '3.1', 'Fibroblast': '5.3', 'Leukocyte': '7.4', 'Basophil': '107.0', 'Eosinophil': '312.5', 'Neutrophil': '496.9', 'Classical monocyte': '25.8', 'Non-classical monocyte': '66.1', 'Intermediate monocyte': '117.0', 'T-reg': '72.1', 'GdT-cell': '89.5', 'MAIT T-cell': '61.2', 'Memory CD4 T-cell': '76.8', 'Naive CD4 T-cell': '47.0', 'Memory CD8 T-cell': '81.1', 'Naive CD8 T-cell': '43.5', 'Memory B-cell': '50.4', 'Naive B-cell': '38.5', 'Plasmacytoid DC': '47.5', 'Myeloid DC': '92.2', 'NK-cell': '88.9', 'Total PBMC': '83.8', 'Vd2 gdTCR': '67.8', 'Memory CD4 T-cell Th1\\/Th17': '48.0', 'Memory CD4 T-cell Th17': '54.6', 'Memory CD4 T-cell Th2': '54.8', 'Non-Vd2 gdTCR': '73.7', 'Memory CD4 T-cell Th1': '58.8', 'Memory CD4 T-cell TFH': '61.9', 'Terminal effector memory CD4 T-cell': '72.8', 'Central memory CD8 T-cell': '59.9', 'Effector memory CD8 T-cell': '90.7', 'Terminal effector memory CD8 T-cell': '75.8', 'Non-switched memory B-cell': '52.6', 'Plasmablast': '62.3', 'Switched memory B-cell': '55.8', 'Exhausted memory B-cell': '52.1', 'Progenitor cell': '44.7', 'Memory T-reg': '82.4', 'Naive CD4 T-cell activated': '133.9', 'Naive CD8 T-cell activated': '163.4', 'Naive T-reg': '54.7'} | 2IWG, 5JPX, 5OLM, 6FGA, 6S53, 7BBD, 8A58 | {'Adipose Tissue': 21.42795099667774, 'Adrenal Gland': 16.707763565891472, 'Bladder': 21.861904761904764, 'Blood': 61.11958557588805, 'Blood Vessel': 22.62928389513109, 'Brain': 4.305000416351249, 'Breast': 20.001740740740743, 'Cervix Uteri': 26.420526315789473, 'Colon': 23.40817458279846, 'Esophagus': 21.74157577854671, 'Fallopian Tube': 25.39, 'Heart': 6.66628106852497, 'Kidney': 13.61479775280899, 'Liver': 10.388, 'Lung': 32.00464878892734, 'Muscle': 3.944284806973848, 'Nerve': 25.39305008077545, 'Ovary': 30.51811111111111, 'Pancreas': 6.808080182926829, 'Pituitary': 12.995699646643107, 'Prostate': 21.00597551020408, 'Salivary Gland': 16.434148148148147, 'Skin': 17.851811498065228, 'Small Intestine': 28.907085561497325, 'Spleen': 50.16024896265561, 'Stomach': 19.072721448467966, 'Testis': 6.377013850415512, 'Thyroid': 21.553307810107196, 'Uterus': 29.83549295774648, 'Vagina': 21.551141025641027} | TRIM5 | MASGILVNVKEEVTCPICLELLTQPLSLDCGHSFCQACLTANHKKSMLDKGESSCPVCRISYQPENIRPNRHVANIVEKLREVKLSPEGQKVDHCARHGEKLLLFCQEDGKVICWLCERSQEHRGHHTFLTEEVAREYQVKLQAALEMLRQKQQEAEELEADIREEKASWKTQIQYDKTNVLADFEQLRDILDWEESNELQNLEKEEEDILKSLTNSETEMVQQTQSLRELISDLEHRLQGSVMELLQGVDGVIKRTENVTLKKPETFPKNQRRVFRAPDLKGMLEVFRELTDVRRYWVDVTVAPNNISCAVISEDKRQVSSPKPQIIYGARGTRYQTFVNFNYCTGILGSQSITSGKHYWEVDVSKKTAWILGVCAGFQPDAMCNIEKNENYQPKYGYWVIGLEEGVKCSAFQDSSFHTPSVPFIVPLSVIICPDRVGVFLDYEACTVSFFNITNHGFLIYKFSHCSFSQPVFPYLNPRKCGVPMTLCSPSS | Homo sapiens | Cytoplasm, Nucleus | Low tissue specificity | {'Ciliated cells': '6.4', 'Basal respiratory cells': '8.3', 'Club cells': '14.2', 'Ionocytes': '7.0', 'Mucus glandular cells': '9.8', 'Serous glandular cells': '14.2', 'Gastric mucus-secreting cells': '7.7', 'Proximal enterocytes': '6.4', 'Paneth cells': '5.5', 'Distal enterocytes': '5.2', 'Intestinal goblet cells': '11.5', 'Exocrine glandular cells': '-0.438', 'Basal prostatic cells': '17.1', 'Prostatic glandular cells': '13.8', 'Breast glandular cells': '0.491', 'Breast myoepithelial cells': '0.595', 'Glandular and luminal cells': '13.2', 'Secretory cells': '14.1', 'Basal keratinocytes': '7.3', 'Suprabasal keratinocytes': '10.3', 'Basal squamous epithelial cells': '9.3', 'Squamous epithelial cells': '6.9', 'Alveolar cells type 1': '0.133', 'Alveolar cells type 2': '-0.113', 'Salivary duct cells': '8.6', 'Ductal cells': '0.490', 'Hepatocytes': '0.447', 'Cholangiocytes': '1.9', 'Proximal tubular cells': '0.175', 'Distal tubular cells': '3.1', 'Collecting duct cells': '9.7', 'Mesothelial cells': '0.470', 'Sertoli cells': '0.457', 'Granulosa cells': '8.8', 'Enteroendocrine cells': '4.6', 'Pancreatic endocrine cells': '1.7', 'Leydig cells': '0.594', 'Excitatory neurons': '2.9', 'Inhibitory neurons': '1.4', 'Cone photoreceptor cells': '0.0', 'Rod photoreceptor cells': '0.0', 'Bipolar cells': '1.1', 'Horizontal cells': '0.6', 'Astrocytes': '4.6', 'Oligodendrocyte precursor cells': '2.8', 'Oligodendrocytes': '1.0', 'Microglial cells': '18.8', 'Muller glia cells': '7.4', 'Schwann cells': '0.043', 'Spermatogonia': '0.455', 'Spermatocytes': '0.041', 'Early spermatids': '-0.459', 'Late spermatids': '-0.645', 'Oocytes': '8.1', 'Cytotrophoblasts': '7.7', 'Syncytiotrophoblasts': '7.4', 'Extravillous trophoblasts': '11.1', 'Endothelial cells': '16.2', 'Lymphatic endothelial cells': '17.8', 'Cardiomyocytes': '0.387', 'Skeletal myocytes': '-0.014', 'Smooth muscle cells': '12.0', 'Adipocytes': '13.0', 'Melanocytes': '0.095', 'Fibroblasts': '12.4', 'Peritubular cells': '0.587', 'Endometrial stromal cells': '12.3', 'Ovarian stromal cells': '12.2', 'Undifferentiated cells': '6.5', 'T-cells': '9.3', 'B-cells': '9.4', 'Plasma cells': '7.4', 'Nk-cells': '12.3', 'Granulocytes': '6.0', 'Monocytes': '10.8', 'Macrophages': '12.1', 'Hofbauer cells': '6.7', 'Kupffer cells': '19.0', 'Dendritic cells': '22.9', 'Langerhans cells': '0.264', 'Erythroid cells': '-0.110', 'Adipocytes (Subcutaneous)': '-0.439', 'Adipocytes (Visceral)': '-0.420', 'Breast glandular cells (progenitors)': '0.327', 'Adipocytes (Breast)': '-0.548', 'Colon enterocytes': '-0.079', 'Colon enteroendocrine cells': '0.297', 'Enteric glia cells': '0.432', 'Mitotic cells (Colon)': '0.050', 'Mitotic cells (Heart)': '0.574', 'Podocytes': '-0.131', 'Ascending Loop of Henle cells': '0.466', 'Intercalated cells': '-0.099', 'Cholangiocyte': '0.261', 'NK-cells (Liver)': '-0.246', 'Respiratory ciliated cells': '-0.081', 'Mitotic cells (Lung)': '0.138', 'NK-cells (Lung)': '0.316', 'B-cells (Lung)': '0.079', 'Alpha cells': '0.331', 'Beta cells': '0.208', 'Prostate glandular cells': '0.215', 'Prostate basal glandular cells': '0.350', 'Urothelial cells': '0.233', 'Keratinocyte (other)': '0.228', 'Keratinocyte (granular)': '-0.204', 'Hair cortex cells': '-0.042', 'Inner root sheath cells': '-0.002', 'Outer root sheath cells': '0.278', 'Sebaceous gland cells': '0.086', 'Eccrine sweat gland cells': '0.149', 'Adipocytes (Skin)': '-0.068', 'Mitotic cells (Skin)': '0.453', 'Parietal cells': '-0.415', 'Chief cells': '-0.210', 'Gastric mucous cells': '-0.145', 'Gastric enteroendocrine cells': '-0.137', 'Mitotic cells (Stomach)': '0.228', 'Parafollicular cells': '0.037', 'Thyroid glandular cells': '0.277', 'Mitotic cells (Thyroid)': '0.064', 'Adrenal cortex cells': '0.476', 'Adrenal medulla cells': '-0.056', 'Mitotic cells (Adrenal gland)': '0.364', 'Minor salivary glandular cells': '0.160', 'Minor salivary gland ductal cells': '0.304', 'Minor salivary gland basal cells': '0.178', 'Mitotic cells (Minor salivary gland)': '0.229', 'Adipocytes (Minor salivary gland)': '0.048', 'Somatotropes': '-0.144', 'Lactotropes': '-0.410', 'Gonadotropes': '0.035', 'Corticotropes': '-0.378', 'Thyrotropes': '-0.210', 'Undifferentiated cells (Pituitary gland)': '0.475', 'Mitotic cells (Spleen)': '-0.122', 'Platelets': '-0.076', 'Erythrocytes': '-0.068', 'Hematopoietic stem cells': '-0.180', 'B-cells (Spleen)': '0.213', 'NK-cells (Spleen)': '0.354', 'Amygdala excitatory': '11.9', 'Cerebellar inhibitory': '4.8', 'Cge interneuron': '4.0', 'Deep-layer corticothalamic and 6b': '32.8', 'Deep-layer intratelencephalic': '16.5', 'Deep-layer near-projecting': '56.0', 'Eccentric medium spiny neuron': '8.6', 'Hippocampal ca1-3': '30.6', 'Hippocampal ca4': '7.2', 'Hippocampal dentate gyrus': '6.0', 'Lamp5-lhx6 and chandelier': '4.0', 'Lower rhombic lip': '23.7', 'Mammillary body': '9.1', 'Medium spiny neuron': '7.2', 'Mge interneuron': '4.0', 'Midbrain-derived inhibitory': '5.3', 'Miscellaneous': '25.8', 'Splatter': '11.1', 'Thalamic excitatory': '12.0', 'Upper rhombic lip': '1.6', 'Upper-layer intratelencephalic': '6.1', 'Astrocyte': '12.0', 'Bergmann glia': '2.8', 'Central nervous system macrophage': '74.2', 'Choroid plexus epithelial cell': '42.4', 'Committed oligodendrocyte precursor': '5.6', 'Ependymal cell': '29.0', 'Oligodendrocyte': '1.1', 'Oligodendrocyte precursor cell': '1.6', 'Endothelial cell': '30.7', 'Pericyte': '18.6', 'Vascular associated smooth muscle cell': '12.6', 'Fibroblast': '31.2', 'Leukocyte': '42.1', 'Basophil': '43.5', 'Eosinophil': '9.6', 'Neutrophil': '110.7', 'Classical monocyte': '12.4', 'Non-classical monocyte': '18.5', 'Intermediate monocyte': '44.7', 'T-reg': '16.2', 'GdT-cell': '4.7', 'MAIT T-cell': '30.0', 'Memory CD4 T-cell': '3.9', 'Naive CD4 T-cell': '23.2', 'Memory CD8 T-cell': '4.1', 'Naive CD8 T-cell': '19.7', 'Memory B-cell': '3.6', 'Naive B-cell': '14.7', 'Plasmacytoid DC': '62.1', 'Myeloid DC': '41.6', 'NK-cell': '25.7', 'Total PBMC': '31.3', 'Vd2 gdTCR': '17.1', 'Memory CD4 T-cell Th1\\/Th17': '14.8', 'Memory CD4 T-cell Th17': '12.8', 'Memory CD4 T-cell Th2': '14.3', 'Non-Vd2 gdTCR': '28.1', 'Memory CD4 T-cell Th1': '15.0', 'Memory CD4 T-cell TFH': '16.1', 'Terminal effector memory CD4 T-cell': '33.9', 'Central memory CD8 T-cell': '22.7', 'Effector memory CD8 T-cell': '26.1', 'Terminal effector memory CD8 T-cell': '28.9', 'Non-switched memory B-cell': '27.5', 'Plasmablast': '38.8', 'Switched memory B-cell': '27.4', 'Exhausted memory B-cell': '29.0', 'Progenitor cell': '46.7', 'Memory T-reg': '12.8', 'Naive CD4 T-cell activated': '45.1', 'Naive CD8 T-cell activated': '39.3', 'Naive T-reg': '21.6'} | 2ECV, 2YRG | {'Adipose Tissue': 10.969098837209302, 'Adrenal Gland': 13.147356589147288, 'Bladder': 12.744380952380952, 'Blood': 13.579995801937567, 'Blood Vessel': 16.373662172284643, 'Brain': 1.5696437925813775, 'Breast': 10.99218954248366, 'Cervix Uteri': 20.141052631578948, 'Colon': 9.455770218228498, 'Esophagus': 9.55905051903114, 'Fallopian Tube': 17.538888888888888, 'Heart': 3.8654873403019745, 'Kidney': 7.739887640449439, 'Liver': 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0.51, 0.58, 0.58, 0.7, 0.67, 0.48, 0.48, 0.52, 0.63, 0.39, 0.5, 0.62, 0.33, 0.53, 0.65, 0.39, 0.53, 0.5, 0.55, 0.55, 0.46, 0.51, 0.58, 0.6, 0.51, 0.58, 0.69, 0.46, 0.62, 0.54, 0.3, 0.15, 0.53, 0.64, 0.39, 0.4, 0.63, 0.63, 0.18, 0.57, 0.69, 0.52, 0.25, 0.5, 0.63, 0.34, 0.43, 0.53, 0.55, 0.13, 0.65, 0.49, 0.53, 0.37, 0.59, 0.61, 0.18, 0.38, 0.43, 0.54, 0.29, 0.54, 0.58, 0.11, 0.51, 0.54, 0.24, 0.36, 0.53, 0.62, 0.22, 0.73, 0.84, 0.42, 0.47, 0.66, 0.72, 0.42, 0.43, 0.61, 0.62, 0.58, 0.3, 0.65, 0.44, 0.05, 0.46, 0.6, 0.48, 0.43, 0.71, 0.71, 0.42, 0.77, 0.64, 0.71, 0.92, 0.32, 0.79, 0.69, 0.34, 0.42, 0.83, 0.9, 0.7, 0.65, 0.6, 0.71, 0.56, 0.9, 0.81, 0.57, 0.61, 0.39, 0.69, 0.25, 0.39, 0.54, 0.38, 0.23, 0.42, 0.57, 0.52, 0.08, 0.59, 0.36, 0.09, 0.4, 0.76, 0.39, 0.21, 0.32, 0.46, 0.11, 0.29, 0.02, 0.4, 0.74, 0.28, 1.0, 0.34, 0.21, 0.3, 0.18, 0.46, 0.29, 0.28, 0.93, 0.57, 0.5, 0.17, 0.39, 0.0, 0.21, 0.07, 0.34, 0.91, 0.57, 0.64, 0.53, 0.45, 0.64, 0.29, 0.99, 0.93, 0.71, 0.39, 0.76, 0.52, 0.69, 0.39, 0.62, 0.56, 0.58, 0.25, 0.79, 0.61, 0.02, 0.02, 0.0, 0.0, 0.13, 0.1, 0.45, 0.69, 0.53, 0.07, 0.52, 0.6, 0.33, 0.42, 0.21, 0.0, 0.01, 0.0, 0.0, 0.34, 0.02, 0.36, 0.81, 0.07, 0.48, 0.23, 0.0, 0.01, 0.0, 0.01, 0.0, 0.0, 0.18, 0.13, 0.24, 0.5, 0.73, 0.88, 0.34, 0.63, 0.93, 0.48, 0.2, 0.29, 0.49, 0.25, 0.24, 0.21, 0.03, 0.0, 0.18, 0.53, 0.39, 0.08, 0.08, 0.03, 0.0, 0.0, 0.01, 0.04, 0.42, 0.66, 0.25, 0.68, 0.53, 0.04, 0.15, 0.0, 0.01, 0.37, 0.43, 0.2, 0.9, 0.75, 0.92, 0.68, 0.56, 0.51, 0.64, 0.08, 0.57, 0.45, 0.22, 0.8, 0.14, 0.92, 0.26, 0.89, 0.49, 0.42, 0.05, 0.42, 0.2, 0.0, 0.0, 0.01, 0.09, 0.0, 0.09, 0.18, 0.66, 0.53, 0.29, 0.12, 0.0, 0.06, 0.0, 0.03, 0.01, 0.17, 0.38, 0.13, 0.58, 0.0, 0.39, 0.47, 0.12, 0.2, 0.55, 0.06, 0.67, 0.86, 0.05, 0.71, 0.14, 0.89, 0.54, 0.42, 0.0, 0.23, 0.05, 0.02, 0.04, 0.03, 0.0, 0.17, 0.68, 0.09, 0.59, 0.39, 0.38, 0.0, 0.26, 0.03, 0.11, 0.34, 0.51, 0.92, 0.5] | RING finger | Component of a SCF(SKP2)-like complex containing CUL1, SKP1, TRIM21 and SKP2. | SCF | null | IRF8, CALR, CUL1, FBXW11, HSPA5, IKBKB, IRF3, SKP1 , VCP,SKP2, DCP2 ,ULK1, BECN1,GABARAP, GABARAPL1, GABARAPL2 , MAP1LC3C,SQSTM1,IRF3 , NMI, IFI35 , CUL1, TRIM21 | USP4, IKBKB, TRIM21, CDKN1B, IRF3, IRF8, MNI | mono, 63 | null | UBE2D2, UBE2D1, UBE2E1, UBE2E2 | Homotrimer | null | 90.718042 | 0.406716 | 86.277748 | 0.430751 | 1,596 |
P19474 | Q9H211 | 16407252 | UbiNet, UbiBrowser | TRIM21 | MASAARLTMMWEEVTCPICLDPFVEPVSIECGHSFCQECISQVGKGGGSVCPVCRQRFLLKNLRPNRQLANMVNNLKEISQEAREGTQGERCAVHGERLHLFCEKDGKALCWVCAQSRKHRDHAMVPLEEAAQEYQEKLQVALGELRRKQELAEKLEVEIAIKRADWKKTVETQKSRIHAEFVQQKNFLVEEEQRQLQELEKDEREQLRILGEKEAKLAQQSQALQELISELDRRCHSSALELLQEVIIVLERSESWNLKDLDITSPELRSVCHVPGLKKMLRTCAVHITLDPDTANPWLILSEDRRQVRLGDTQQSIPGNEERFDSYPMVLGAQHFHSGKHYWEVDVTGKEAWDLGVCRDSVRRKGHFLLSSKSGFWTIWLWNKQKYEAGTYPQTPLHLQVPPCQVGIFLDYEAGMVSFYNITDHGSLIYSFSECAFTGPLRPFFSPGFNDGGKNTAPLTLCPLNIGSQGSTDY | Homo sapiens | Cytoplasm, Cytoplasmic vesicle, autophagosome, Nucleus, Cytoplasm, P-body, Cytoplasm, Stress granule | Low tissue specificity | {'Ciliated cells': '3.8', 'Basal respiratory cells': '6.8', 'Club cells': '5.8', 'Ionocytes': '3.7', 'Mucus glandular cells': '4.8', 'Serous glandular cells': '2.3', 'Gastric mucus-secreting cells': '8.8', 'Proximal enterocytes': '8.9', 'Paneth cells': '3.9', 'Distal enterocytes': '8.5', 'Intestinal goblet cells': '8.4', 'Exocrine glandular cells': '-0.716', 'Basal prostatic cells': '5.4', 'Prostatic glandular cells': '5.0', 'Breast glandular cells': '0.298', 'Breast myoepithelial cells': '0.351', 'Glandular and luminal cells': '5.9', 'Secretory cells': '8.4', 'Basal keratinocytes': '3.2', 'Suprabasal keratinocytes': '2.7', 'Basal squamous epithelial cells': '6.4', 'Squamous epithelial cells': '4.3', 'Alveolar cells type 1': '0.116', 'Alveolar cells type 2': '0.115', 'Salivary duct cells': '3.0', 'Ductal cells': '0.700', 'Hepatocytes': '0.503', 'Cholangiocytes': '11.4', 'Proximal tubular cells': '0.175', 'Distal tubular cells': '0.0', 'Collecting duct cells': '5.8', 'Mesothelial cells': '0.451', 'Sertoli cells': '0.479', 'Granulosa cells': '4.8', 'Enteroendocrine cells': '3.7', 'Pancreatic endocrine cells': '3.4', 'Leydig cells': '0.632', 'Excitatory neurons': '0.2', 'Inhibitory neurons': '0.1', 'Cone photoreceptor cells': '0.0', 'Rod photoreceptor cells': '0.0', 'Bipolar cells': '0.7', 'Horizontal cells': '0.6', 'Astrocytes': '0.0', 'Oligodendrocyte precursor cells': '0.9', 'Oligodendrocytes': '0.1', 'Microglial cells': '1.8', 'Muller glia cells': '2.4', 'Schwann cells': '0.099', 'Spermatogonia': '0.401', 'Spermatocytes': '-0.062', 'Early spermatids': '-0.578', 'Late spermatids': '-0.618', 'Oocytes': '1.5', 'Cytotrophoblasts': '6.6', 'Syncytiotrophoblasts': '9.8', 'Extravillous trophoblasts': '10.0', 'Endothelial cells': '7.8', 'Lymphatic endothelial cells': '6.9', 'Cardiomyocytes': '0.335', 'Skeletal myocytes': '-0.080', 'Smooth muscle cells': '6.3', 'Adipocytes': '8.3', 'Melanocytes': '0.101', 'Fibroblasts': '6.5', 'Peritubular cells': '0.579', 'Endometrial stromal cells': '4.5', 'Ovarian stromal cells': '6.7', 'Undifferentiated cells': '5.9', 'T-cells': '9.9', 'B-cells': '8.8', 'Plasma cells': '5.0', 'Nk-cells': '15.1', 'Granulocytes': '6.2', 'Monocytes': '7.8', 'Macrophages': '8.5', 'Hofbauer cells': '9.9', 'Kupffer cells': '10.3', 'Dendritic cells': '8.0', 'Langerhans cells': '0.466', 'Erythroid cells': '-0.084', 'Adipocytes (Subcutaneous)': '-0.368', 'Adipocytes (Visceral)': '-0.167', 'Breast glandular cells (progenitors)': '0.190', 'Adipocytes (Breast)': '-0.382', 'Colon enterocytes': '0.004', 'Colon enteroendocrine cells': '0.196', 'Enteric glia cells': '-0.129', 'Mitotic cells (Colon)': '0.005', 'Mitotic cells (Heart)': '0.486', 'Podocytes': '-0.114', 'Ascending Loop of Henle cells': '0.371', 'Intercalated cells': '-0.097', 'Cholangiocyte': '0.375', 'NK-cells (Liver)': '-0.278', 'Respiratory ciliated cells': '-0.022', 'Mitotic cells (Lung)': '0.157', 'NK-cells (Lung)': '0.110', 'B-cells (Lung)': '-0.155', 'Alpha cells': '0.333', 'Beta cells': '0.161', 'Prostate glandular cells': '-0.162', 'Prostate basal glandular cells': '0.286', 'Urothelial cells': '0.283', 'Keratinocyte (other)': '0.121', 'Keratinocyte (granular)': '-0.008', 'Hair cortex cells': '-0.113', 'Inner root sheath cells': '-0.069', 'Outer root sheath cells': '0.125', 'Sebaceous gland cells': '0.110', 'Eccrine sweat gland cells': '0.070', 'Adipocytes (Skin)': '0.019', 'Mitotic cells (Skin)': '0.236', 'Parietal cells': '-0.609', 'Chief cells': '-0.599', 'Gastric mucous cells': '-0.193', 'Gastric enteroendocrine cells': '-0.441', 'Mitotic cells (Stomach)': '0.261', 'Parafollicular cells': '-0.028', 'Thyroid glandular cells': '0.094', 'Mitotic cells (Thyroid)': '0.242', 'Adrenal cortex cells': '0.619', 'Adrenal medulla cells': '0.063', 'Mitotic cells (Adrenal gland)': '0.483', 'Minor salivary glandular cells': '0.582', 'Minor salivary gland ductal cells': '0.072', 'Minor salivary gland basal cells': '0.229', 'Mitotic cells (Minor salivary gland)': '0.376', 'Adipocytes (Minor salivary gland)': '0.211', 'Somatotropes': '-0.121', 'Lactotropes': '-0.287', 'Gonadotropes': '0.004', 'Corticotropes': '-0.352', 'Thyrotropes': '-0.054', 'Undifferentiated cells (Pituitary gland)': '0.486', 'Mitotic cells (Spleen)': '-0.016', 'Platelets': '0.115', 'Erythrocytes': '0.098', 'Hematopoietic stem cells': '0.042', 'B-cells (Spleen)': '0.028', 'NK-cells (Spleen)': '0.157', 'Amygdala excitatory': '0.1', 'Cerebellar inhibitory': '0.2', 'Cge interneuron': '0.3', 'Deep-layer corticothalamic and 6b': '0.3', 'Deep-layer intratelencephalic': '0.1', 'Deep-layer near-projecting': '0.1', 'Eccentric medium spiny neuron': '0.4', 'Hippocampal ca1-3': '0.5', 'Hippocampal ca4': '0.1', 'Hippocampal dentate gyrus': '0.3', 'Lamp5-lhx6 and chandelier': '0.3', 'Lower rhombic lip': '0.2', 'Mammillary body': '0.4', 'Medium spiny neuron': '0.6', 'Mge interneuron': '0.1', 'Midbrain-derived inhibitory': '0.6', 'Miscellaneous': '0.6', 'Splatter': '0.5', 'Thalamic excitatory': '1.3', 'Upper rhombic lip': '0.1', 'Upper-layer intratelencephalic': '0.1', 'Astrocyte': '1.5', 'Bergmann glia': '1.5', 'Central nervous system macrophage': '6.0', 'Choroid plexus epithelial cell': '2.9', 'Committed oligodendrocyte precursor': '1.0', 'Ependymal cell': '1.3', 'Oligodendrocyte': '0.1', 'Oligodendrocyte precursor cell': '2.3', 'Endothelial cell': '6.4', 'Pericyte': '5.3', 'Vascular associated smooth muscle cell': '3.1', 'Fibroblast': '5.3', 'Leukocyte': '7.4', 'Basophil': '107.0', 'Eosinophil': '312.5', 'Neutrophil': '496.9', 'Classical monocyte': '25.8', 'Non-classical monocyte': '66.1', 'Intermediate monocyte': '117.0', 'T-reg': '72.1', 'GdT-cell': '89.5', 'MAIT T-cell': '61.2', 'Memory CD4 T-cell': '76.8', 'Naive CD4 T-cell': '47.0', 'Memory CD8 T-cell': '81.1', 'Naive CD8 T-cell': '43.5', 'Memory B-cell': '50.4', 'Naive B-cell': '38.5', 'Plasmacytoid DC': '47.5', 'Myeloid DC': '92.2', 'NK-cell': '88.9', 'Total PBMC': '83.8', 'Vd2 gdTCR': '67.8', 'Memory CD4 T-cell Th1\\/Th17': '48.0', 'Memory CD4 T-cell Th17': '54.6', 'Memory CD4 T-cell Th2': '54.8', 'Non-Vd2 gdTCR': '73.7', 'Memory CD4 T-cell Th1': '58.8', 'Memory CD4 T-cell TFH': '61.9', 'Terminal effector memory CD4 T-cell': '72.8', 'Central memory CD8 T-cell': '59.9', 'Effector memory CD8 T-cell': '90.7', 'Terminal effector memory CD8 T-cell': '75.8', 'Non-switched memory B-cell': '52.6', 'Plasmablast': '62.3', 'Switched memory B-cell': '55.8', 'Exhausted memory B-cell': '52.1', 'Progenitor cell': '44.7', 'Memory T-reg': '82.4', 'Naive CD4 T-cell activated': '133.9', 'Naive CD8 T-cell activated': '163.4', 'Naive T-reg': '54.7'} | 2IWG, 5JPX, 5OLM, 6FGA, 6S53, 7BBD, 8A58 | {'Adipose Tissue': 21.42795099667774, 'Adrenal Gland': 16.707763565891472, 'Bladder': 21.861904761904764, 'Blood': 61.11958557588805, 'Blood Vessel': 22.62928389513109, 'Brain': 4.305000416351249, 'Breast': 20.001740740740743, 'Cervix Uteri': 26.420526315789473, 'Colon': 23.40817458279846, 'Esophagus': 21.74157577854671, 'Fallopian Tube': 25.39, 'Heart': 6.66628106852497, 'Kidney': 13.61479775280899, 'Liver': 10.388, 'Lung': 32.00464878892734, 'Muscle': 3.944284806973848, 'Nerve': 25.39305008077545, 'Ovary': 30.51811111111111, 'Pancreas': 6.808080182926829, 'Pituitary': 12.995699646643107, 'Prostate': 21.00597551020408, 'Salivary Gland': 16.434148148148147, 'Skin': 17.851811498065228, 'Small Intestine': 28.907085561497325, 'Spleen': 50.16024896265561, 'Stomach': 19.072721448467966, 'Testis': 6.377013850415512, 'Thyroid': 21.553307810107196, 'Uterus': 29.83549295774648, 'Vagina': 21.551141025641027} | CDT1 | MEQRRVTDFFARRRPGPPRIAPPKLACRTPSPARPALRAPASATSGSRKRARPPAAPGRDQARPPARRRLRLSVDEVSSPSTPEAPDIPACPSPGQKIKKSTPAAGQPPHLTSAQDQDTISELASCLQRARELGARVRALKASAQDAGESCTPEAEGRPEEPCGEKAPAYQRFHALAQPGLPGLVLPYKYQVLAEMFRSMDTIVGMLHNRSETPTFAKVQRGVQDMMRRRFEECNVGQIKTVYPASYRFRQERSVPTFKDGTRRSDYQLTIEPLLEQEADGAAPQLTASRLLQRRQIFSQKLVEHVKEHHKAFLASLSPAMVVPEDQLTRWHPRFNVDEVPDIEPAALPQPPATEKLTTAQEVLARARNLISPRMEKALSQLALRSAAPSSPGSPRPALPATPPATPPAASPSALKGVSQDLLERIRAKEAQKQLAQMTRCPEQEQRLQRLERLPELARVLRSVFVSERKPALSMEVACARMVGSCCTIMSPGEMEKHLLLLSELLPDWLSLHRIRTDTYVKLDKAADLAHITARLAHQTRAEEGL | Homo sapiens | Nucleus, Chromosome, centromere, kinetochore | Tissue enriched (bone) | {'Ciliated cells': '2.8', 'Basal respiratory cells': '1.1', 'Club cells': '4.6', 'Ionocytes': '0.0', 'Mucus glandular cells': '0.8', 'Serous glandular cells': '2.4', 'Gastric mucus-secreting cells': '9.4', 'Proximal enterocytes': '1.1', 'Paneth cells': '3.3', 'Distal enterocytes': '1.5', 'Intestinal goblet cells': '11.5', 'Exocrine glandular cells': '-0.394', 'Basal prostatic cells': '0.3', 'Prostatic glandular cells': '0.3', 'Breast glandular cells': '0.428', 'Breast myoepithelial cells': '0.477', 'Glandular and luminal cells': '2.2', 'Secretory cells': '2.9', 'Basal keratinocytes': '13.4', 'Suprabasal keratinocytes': '6.5', 'Basal squamous epithelial cells': '7.3', 'Squamous epithelial cells': '10.0', 'Alveolar cells type 1': '-0.274', 'Alveolar cells type 2': '0.144', 'Salivary duct cells': '2.6', 'Ductal cells': '0.455', 'Hepatocytes': '0.170', 'Cholangiocytes': '1.9', 'Proximal tubular cells': '0.339', 'Distal tubular cells': '0.0', 'Collecting duct cells': '1.9', 'Mesothelial cells': '0.064', 'Sertoli cells': '0.174', 'Granulosa cells': '6.5', 'Enteroendocrine cells': '4.9', 'Pancreatic endocrine cells': '5.1', 'Leydig cells': '0.177', 'Excitatory neurons': '0.2', 'Inhibitory neurons': '0.8', 'Cone photoreceptor cells': '1.7', 'Rod photoreceptor cells': '2.2', 'Bipolar cells': '1.0', 'Horizontal cells': '0.0', 'Astrocytes': '0.6', 'Oligodendrocyte precursor cells': '0.0', 'Oligodendrocytes': '0.6', 'Microglial cells': '0.0', 'Muller glia cells': '0.1', 'Schwann cells': '0.069', 'Spermatogonia': '0.456', 'Spermatocytes': '0.403', 'Early spermatids': '-0.010', 'Late spermatids': '-0.195', 'Oocytes': '27.2', 'Cytotrophoblasts': '55.2', 'Syncytiotrophoblasts': '27.1', 'Extravillous trophoblasts': '94.5', 'Endothelial cells': '1.9', 'Lymphatic endothelial cells': '0.1', 'Cardiomyocytes': '0.310', 'Skeletal myocytes': '-0.106', 'Smooth muscle cells': '1.6', 'Adipocytes': '0.6', 'Melanocytes': '0.433', 'Fibroblasts': '3.2', 'Peritubular cells': '0.080', 'Endometrial stromal cells': '1.2', 'Ovarian stromal cells': '0.9', 'Undifferentiated cells': '58.8', 'T-cells': '4.4', 'B-cells': '2.1', 'Plasma cells': '24.1', 'Nk-cells': '3.4', 'Granulocytes': '0.5', 'Monocytes': '0.7', 'Macrophages': '2.5', 'Hofbauer cells': '13.4', 'Kupffer cells': '3.7', 'Dendritic cells': '1.6', 'Langerhans cells': '0.256', 'Erythroid cells': '0.073', 'Adipocytes (Subcutaneous)': '-0.161', 'Adipocytes (Visceral)': '-0.136', 'Breast glandular cells (progenitors)': '0.478', 'Adipocytes (Breast)': '-0.403', 'Colon enterocytes': '0.351', 'Colon enteroendocrine cells': '0.008', 'Enteric glia cells': '-0.108', 'Mitotic cells (Colon)': '0.643', 'Mitotic cells (Heart)': '0.718', 'Podocytes': '-0.021', 'Ascending Loop of Henle cells': '0.255', 'Intercalated cells': '0.023', 'Cholangiocyte': '0.194', 'NK-cells (Liver)': '0.016', 'Respiratory ciliated cells': '0.126', 'Mitotic cells (Lung)': '0.831', 'NK-cells (Lung)': '-0.136', 'B-cells (Lung)': '0.014', 'Alpha cells': '0.273', 'Beta cells': '0.122', 'Prostate glandular cells': '0.031', 'Prostate basal glandular cells': '0.365', 'Urothelial cells': '0.442', 'Keratinocyte (other)': '0.426', 'Keratinocyte (granular)': '-0.160', 'Hair cortex cells': '-0.079', 'Inner root sheath cells': '0.050', 'Outer root sheath cells': '0.102', 'Sebaceous gland cells': '0.138', 'Eccrine sweat gland cells': '-0.219', 'Adipocytes (Skin)': '-0.303', 'Mitotic cells (Skin)': '0.657', 'Parietal cells': '0.123', 'Chief cells': '0.150', 'Gastric mucous cells': '0.566', 'Gastric enteroendocrine cells': '0.275', 'Mitotic cells (Stomach)': '0.882', 'Parafollicular cells': '0.040', 'Thyroid glandular cells': '0.217', 'Mitotic cells (Thyroid)': '0.447', 'Adrenal cortex cells': '0.388', 'Adrenal medulla cells': '0.120', 'Mitotic cells (Adrenal gland)': '0.426', 'Minor salivary glandular cells': '0.152', 'Minor salivary gland ductal cells': '-0.307', 'Minor salivary gland basal cells': '0.713', 'Mitotic cells (Minor salivary gland)': '0.902', 'Adipocytes (Minor salivary gland)': '0.230', 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0.576026 | 1,214 |
P19812 | P16658 | 32118579 | UbiNet, UbiBrowser | UBR1 | MSVADDDLGSLQGHIRRTLRSIHNLPYFRYTRGPTERADMSRALKEFIYRYLYFVISNSGENLPTLFNAHPKQKLSNPELTVFPDSLEDAVDIDKITSQQTIPFYKIDESRIGDVHKHTGRNCGRKFKIGEPLYRCHECGCDDTCVLCIHCFNPKDHVNHHVCTDICTEFTSGICDCGDEEAWNSPLHCKAEEQENDISEDPATNADIKEEDVWNDSVNIALVELVLAEVFDYFIDVFNQNIEPLPTIQKDITIKLREMTQQGKMYERAQFLNDLKYENDYMFDGTTTAKTSPSNSPEASPSLAKIDPENYTVIIYNDEYHNYSQATTALRQGVPDNVHIDLLTSRIDGEGRAMLKCSQDLSSVLGGFFAVQTNGLSATLTSWSEYLHQETCKYIILWITHCLNIPNSSFQTTFRNMMGKTLCSEYLNATECRDMTPVVEKYFSNKFDKNDPYRYIDLSILADGNQIPLGHHKILPESSTHSLSPLINDVETPTSRTYSNTRLQHILYFDNRYWKRLRKDIQNVIIPTLASSNLYKPIFCQQVVEIFNHITRSVAYMDREPQLTAIRECVVQLFTCPTNAKNIFENQSFLDIVWSIIDIFKEFCKVEGGVLIWQRVQKSNLTKSYSISFKQGLYTVETLLSKVHDPNIPLRPKEIISLLTLCKLFNGAWKIKRKEGEHVLHEDQNFISYLEYTTSIYSIIQTAEKVSEKSKDSIDSKLFLNAIRIISSFLGNRSLTYKLIYDSHEVIKFSVSHERVAFMNPLQTMLSFLIEKVSLKDAYEALEDCSDFLKISDFSLRSVVLCSQIDVGFWVRNGMSVLHQASYYKNNPELGSYSRDIHLNQLAILWERDDIPRIIYNILDRWELLDWFTGEVDYQHTVYEDKISFIIQQFIAFIYQILTERQYFKTFSSLKDRRMDQIKNSIIYNLYMKPLSYSKLLRSVPDYLTEDTTEFDEALEEVSVFVEPKGLADNGVFKLKASLYAKVDPLKLLNLENEFESSATIIKSHLAKDKDEIAKVVLIPQVSIKQLDKDALNLGAFTRNTVFAKVVYKLLQVCLDMEDSTFLNELLHLVHGIFRDDELINGKDSIPEAYLSKPICNLLLSIANAKSDVFSESIVRKADYLLEKMIMKKPNELFESLIASFGNQYVNDYKDKKLRQGVNLQETEKERKRRLAKKHQARLLAKFNNQQTKFMKEHESEFDEQDNDVDMVGEKVYESEDFTCALCQDSSSTDFFVIPAYHDHSPIFRPGNIFNPNEFMPMWDGFYNDDEKQAYIDDDVLEALKENGSCGSRKVFVSCNHHIHHNCFKRYVQKKRFSSNAFICPLCQTFSNCTLPLCQTSKANTGLSLDMFLESELSLDTLSRLFKPFTEENYRTINSIFSLMISQCQGFDKAVRKRANFSHKDVSLILSVHWANTISMLEIASRLEKPYSISFFRSREQKYKTLKNILVCIMLFTFVIGKPSMEFEPYPQQPDTVWNQNQLFQYIVRSALFSPVSLRQTVTEALTTFSRQFLRDFLQGLSDAEQVTKLYAKASKIGDVLKVSEQMLFALRTISDVRMEGLDSESIIYDLAYTFLLKSLLPTIRRCLVFIKVLHELVKDSENETLVINGHEVEEELEFEDTAEFVNKALKMITEKESLVDLLTTQESIVSHPYLENIPYEYCGIIKLIDLSKYLNTYVTQSKEIKLREERSQHMKNADNRLDFKICLTCGVKVHLRADRHEMTKHLNKNCFKPFGAFLMPNSSEVCLHLTQPPSNIFISAPYLNSHGEVGRNAMRRGDLTTLNLKRYEHLNRLWINNEIPGYISRVMGDEFRVTILSNGFLFAFNREPRPRRIPPTDEDDEDMEEGEDGFFTEGNDEMDVDDETGQAANLFGVGAEGIAGGGVRDFFQFFENFRNTLQPQGNGDDDAPQNPPPILQFLGPQFDGATIIRNTNPRNLDEDDSDDNDDSDEREIW | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) | null | Not found | {} | 3NIH, 3NII, 3NIJ, 3NIK, 3NIL, 3NIM, 3NIN, 3NIS, 3NIT, 6KGI, 7MEX, 7MEY | {} | SEN2 | MSKGRVNQKRYKYPLPIHPVDDLPELILHNPLSWLYWAYRYYKSTNALNDKVHVDFIGDTTLHITVQDDKQMLYLWNNGFFGTGQFSRSEPTWKARTEARLGLNDTPLHNRGGTKSNTETEMTLEKVTQQRRLQRLEFKKERAKLERELLELRKKGGHIDEENILLEKQRESLRKFKLKQTEDVGIVAQQQDISESNLRDEDNNLLDENGDLLPLESLELMPVEAMFLTFALPVLDISPACLAGKLFQFDAKYKDIHSFVRSYVIYHHYRSHGWCVRSGIKFGCDYLLYKRGPPFQHAEFCVMGLDHDVSKDYTWYSSIARVVGGAKKTFVLCYVERLISEQEAIALWKSNNFTKLFNSFQVGEVLYKRWVPGRNRD | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) | Nucleus, Endomembrane system, Mitochondrion outer membrane | Not found | {} | null | {} | [33.3, 39.69, 36.02, 42.83, 46.5, 56.88, 66.67, 74.53, 75.96, 81.03, 85.25, 87.04, 85.82, 90.1, 91.73, 90.88, 90.56, 92.49, 93.64, 92.67, 92.7, 91.33, 89.63, 88.22, 88.41, 83.32, 86.52, 89.61, 83.77, 81.23, 83.32, 79.81, 78.84, 76.02, 77.95, 81.95, 83.85, 80.53, 84.56, 89.02, 86.43, 86.67, 89.78, 92.82, 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P19812 | P38147 | nan, 28515311, nan | degron_data, Degronopedia, degron_data | UBR1 | MSVADDDLGSLQGHIRRTLRSIHNLPYFRYTRGPTERADMSRALKEFIYRYLYFVISNSGENLPTLFNAHPKQKLSNPELTVFPDSLEDAVDIDKITSQQTIPFYKIDESRIGDVHKHTGRNCGRKFKIGEPLYRCHECGCDDTCVLCIHCFNPKDHVNHHVCTDICTEFTSGICDCGDEEAWNSPLHCKAEEQENDISEDPATNADIKEEDVWNDSVNIALVELVLAEVFDYFIDVFNQNIEPLPTIQKDITIKLREMTQQGKMYERAQFLNDLKYENDYMFDGTTTAKTSPSNSPEASPSLAKIDPENYTVIIYNDEYHNYSQATTALRQGVPDNVHIDLLTSRIDGEGRAMLKCSQDLSSVLGGFFAVQTNGLSATLTSWSEYLHQETCKYIILWITHCLNIPNSSFQTTFRNMMGKTLCSEYLNATECRDMTPVVEKYFSNKFDKNDPYRYIDLSILADGNQIPLGHHKILPESSTHSLSPLINDVETPTSRTYSNTRLQHILYFDNRYWKRLRKDIQNVIIPTLASSNLYKPIFCQQVVEIFNHITRSVAYMDREPQLTAIRECVVQLFTCPTNAKNIFENQSFLDIVWSIIDIFKEFCKVEGGVLIWQRVQKSNLTKSYSISFKQGLYTVETLLSKVHDPNIPLRPKEIISLLTLCKLFNGAWKIKRKEGEHVLHEDQNFISYLEYTTSIYSIIQTAEKVSEKSKDSIDSKLFLNAIRIISSFLGNRSLTYKLIYDSHEVIKFSVSHERVAFMNPLQTMLSFLIEKVSLKDAYEALEDCSDFLKISDFSLRSVVLCSQIDVGFWVRNGMSVLHQASYYKNNPELGSYSRDIHLNQLAILWERDDIPRIIYNILDRWELLDWFTGEVDYQHTVYEDKISFIIQQFIAFIYQILTERQYFKTFSSLKDRRMDQIKNSIIYNLYMKPLSYSKLLRSVPDYLTEDTTEFDEALEEVSVFVEPKGLADNGVFKLKASLYAKVDPLKLLNLENEFESSATIIKSHLAKDKDEIAKVVLIPQVSIKQLDKDALNLGAFTRNTVFAKVVYKLLQVCLDMEDSTFLNELLHLVHGIFRDDELINGKDSIPEAYLSKPICNLLLSIANAKSDVFSESIVRKADYLLEKMIMKKPNELFESLIASFGNQYVNDYKDKKLRQGVNLQETEKERKRRLAKKHQARLLAKFNNQQTKFMKEHESEFDEQDNDVDMVGEKVYESEDFTCALCQDSSSTDFFVIPAYHDHSPIFRPGNIFNPNEFMPMWDGFYNDDEKQAYIDDDVLEALKENGSCGSRKVFVSCNHHIHHNCFKRYVQKKRFSSNAFICPLCQTFSNCTLPLCQTSKANTGLSLDMFLESELSLDTLSRLFKPFTEENYRTINSIFSLMISQCQGFDKAVRKRANFSHKDVSLILSVHWANTISMLEIASRLEKPYSISFFRSREQKYKTLKNILVCIMLFTFVIGKPSMEFEPYPQQPDTVWNQNQLFQYIVRSALFSPVSLRQTVTEALTTFSRQFLRDFLQGLSDAEQVTKLYAKASKIGDVLKVSEQMLFALRTISDVRMEGLDSESIIYDLAYTFLLKSLLPTIRRCLVFIKVLHELVKDSENETLVINGHEVEEELEFEDTAEFVNKALKMITEKESLVDLLTTQESIVSHPYLENIPYEYCGIIKLIDLSKYLNTYVTQSKEIKLREERSQHMKNADNRLDFKICLTCGVKVHLRADRHEMTKHLNKNCFKPFGAFLMPNSSEVCLHLTQPPSNIFISAPYLNSHGEVGRNAMRRGDLTTLNLKRYEHLNRLWINNEIPGYISRVMGDEFRVTILSNGFLFAFNREPRPRRIPPTDEDDEDMEEGEDGFFTEGNDEMDVDDETGQAANLFGVGAEGIAGGGVRDFFQFFENFRNTLQPQGNGDDDAPQNPPPILQFLGPQFDGATIIRNTNPRNLDEDDSDDNDDSDEREIW 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P19812 | P41817 | 22199232 | UbiNet, UbiBrowser | UBR1 | 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P19812 | Q12158 | null | degron_data | UBR1 | MSVADDDLGSLQGHIRRTLRSIHNLPYFRYTRGPTERADMSRALKEFIYRYLYFVISNSGENLPTLFNAHPKQKLSNPELTVFPDSLEDAVDIDKITSQQTIPFYKIDESRIGDVHKHTGRNCGRKFKIGEPLYRCHECGCDDTCVLCIHCFNPKDHVNHHVCTDICTEFTSGICDCGDEEAWNSPLHCKAEEQENDISEDPATNADIKEEDVWNDSVNIALVELVLAEVFDYFIDVFNQNIEPLPTIQKDITIKLREMTQQGKMYERAQFLNDLKYENDYMFDGTTTAKTSPSNSPEASPSLAKIDPENYTVIIYNDEYHNYSQATTALRQGVPDNVHIDLLTSRIDGEGRAMLKCSQDLSSVLGGFFAVQTNGLSATLTSWSEYLHQETCKYIILWITHCLNIPNSSFQTTFRNMMGKTLCSEYLNATECRDMTPVVEKYFSNKFDKNDPYRYIDLSILADGNQIPLGHHKILPESSTHSLSPLINDVETPTSRTYSNTRLQHILYFDNRYWKRLRKDIQNVIIPTLASSNLYKPIFCQQVVEIFNHITRSVAYMDREPQLTAIRECVVQLFTCPTNAKNIFENQSFLDIVWSIIDIFKEFCKVEGGVLIWQRVQKSNLTKSYSISFKQGLYTVETLLSKVHDPNIPLRPKEIISLLTLCKLFNGAWKIKRKEGEHVLHEDQNFISYLEYTTSIYSIIQTAEKVSEKSKDSIDSKLFLNAIRIISSFLGNRSLTYKLIYDSHEVIKFSVSHERVAFMNPLQTMLSFLIEKVSLKDAYEALEDCSDFLKISDFSLRSVVLCSQIDVGFWVRNGMSVLHQASYYKNNPELGSYSRDIHLNQLAILWERDDIPRIIYNILDRWELLDWFTGEVDYQHTVYEDKISFIIQQFIAFIYQILTERQYFKTFSSLKDRRMDQIKNSIIYNLYMKPLSYSKLLRSVPDYLTEDTTEFDEALEEVSVFVEPKGLADNGVFKLKASLYAKVDPLKLLNLENEFESSATIIKSHLAKDKDEIAKVVLIPQVSIKQLDKDALNLGAFTRNTVFAKVVYKLLQVCLDMEDSTFLNELLHLVHGIFRDDELINGKDSIPEAYLSKPICNLLLSIANAKSDVFSESIVRKADYLLEKMIMKKPNELFESLIASFGNQYVNDYKDKKLRQGVNLQETEKERKRRLAKKHQARLLAKFNNQQTKFMKEHESEFDEQDNDVDMVGEKVYESEDFTCALCQDSSSTDFFVIPAYHDHSPIFRPGNIFNPNEFMPMWDGFYNDDEKQAYIDDDVLEALKENGSCGSRKVFVSCNHHIHHNCFKRYVQKKRFSSNAFICPLCQTFSNCTLPLCQTSKANTGLSLDMFLESELSLDTLSRLFKPFTEENYRTINSIFSLMISQCQGFDKAVRKRANFSHKDVSLILSVHWANTISMLEIASRLEKPYSISFFRSREQKYKTLKNILVCIMLFTFVIGKPSMEFEPYPQQPDTVWNQNQLFQYIVRSALFSPVSLRQTVTEALTTFSRQFLRDFLQGLSDAEQVTKLYAKASKIGDVLKVSEQMLFALRTISDVRMEGLDSESIIYDLAYTFLLKSLLPTIRRCLVFIKVLHELVKDSENETLVINGHEVEEELEFEDTAEFVNKALKMITEKESLVDLLTTQESIVSHPYLENIPYEYCGIIKLIDLSKYLNTYVTQSKEIKLREERSQHMKNADNRLDFKICLTCGVKVHLRADRHEMTKHLNKNCFKPFGAFLMPNSSEVCLHLTQPPSNIFISAPYLNSHGEVGRNAMRRGDLTTLNLKRYEHLNRLWINNEIPGYISRVMGDEFRVTILSNGFLFAFNREPRPRRIPPTDEDDEDMEEGEDGFFTEGNDEMDVDDETGQAANLFGVGAEGIAGGGVRDFFQFFENFRNTLQPQGNGDDDAPQNPPPILQFLGPQFDGATIIRNTNPRNLDEDDSDDNDDSDEREIW | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) | null | Not found | {} | 3NIH, 3NII, 3NIJ, 3NIK, 3NIL, 3NIM, 3NIN, 3NIS, 3NIT, 6KGI, 7MEX, 7MEY | {} | MCD1 | MVTENPQRLTVLRLATNKGPLAQIWLASNMSNIPRGSVIQTHIAESAKEIAKASGCDDESGDNEYITLRTSGELLQGIVRVYSKQATFLLTDIKDTLTKISMLFKTSQKMTSTVNRLNTVTRVHQLMLEDAVTEREVLVTPGLEFLDDTTIPVGLMAQENSMERKVQGAAPWDTSLEVGRRFSPDEDFEHNNLSSMNLDFDIEEGPITSKSWEEGTRQSSRNFDTHENYIQDDDFPLDDAGTIGWDLGITEKNDQNNDDDDNSVEQGRRLGESIMSEEPTDFGFDLDIEKEAPAGNIDTITDAMTESQPKQTGTRRNSKLLNTKSIQIDEETENSESIASSNTYKEERSNNLLTPQPTNFTTKRLWSEITESMSYLPDPILKNFLSYESLKKRKIHNGREGSIEEPELNVSLNLTDDVISNAGTNDNSFNELTDNMSDFVPIDAGLNEAPFPEENIIDAKTRNEQTTIQTEKVRPTPGEVASKAIVQMAKILRKELSEEKEVIFTDVLKSQANTEPENITKREASRGFFDILSLATEGCIGLSQTEAFGNIKIDAKPALFERFINA | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) | Nucleus, Chromosome, Chromosome, centromere | Not found | {} | 1W1W, 4UX3, 5FRP, 5FRS, 6H8Q, 6QPQ, 6QPW, 6ZZ6 | {} | [33.3, 39.69, 36.02, 42.83, 46.5, 56.88, 66.67, 74.53, 75.96, 81.03, 85.25, 87.04, 85.82, 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null | null | 80.206826 | 0.307764 | 57.434382 | 0.727049 | 1,371 |
P21461 | P42282 | 22199232 | UbiNet, UbiBrowser | sina | MSNKINPKRREPTAAAAGAGATGVATNTSTSTGSSSAGNTSSANTSSSSSSSLSSAGGGDAGMSADLTSLFECPVCFDYVLPPILQCSSGHLVCVSCRSKLTCCPTCRGPLANIRNLAMEKVASNVKFPCKHSGYGCTASLVYTEKTEHEETCECRPYLCPCPGASCKWQGPLDLVMQHLMMSHKSITTLQGEDIVFLATDINLPGAVDWVMMQSCFGHHFMLVLEKQEKYDGHQQFFAIVQLIGSRKEAENFVYRLELNGNRRRLTWEAMPRSIHEGVASAIHNSDCLVFDTSIAQLFADNGNLGINVTISLV | Drosophila melanogaster | Cytoplasm, Nucleus | Not found | {} | null | {} | ttk | MKMASQRFCLRWNNHQSNLLSVFDQLLHAETFTDVTLAVEGQHLKAHKMVLSACSPYFNTLFVSHPEKHPIVILKDVPYSDMKSLLDFMYRGEVSVDQERLTAFLRVAESLRIKGLTEVNDDKPSPAAAAAGAGATGSESTATTPQLQRIQPYLVPQRNRSQAGGLLASAANAGNTPTLPVQPSLLSSALMPKRKRGRPRKLSGSSNGTGNDYDDFDRENMMNDSSDLGNGKMCNESYSGNDDGSDDNQPNAGHTDDLNESRDSLPSKRSKNSKDHRVVSHHEDNSTSVTPTKATPELSQRLFGSSSTTISATAPGGSSTGPSETISLLEISDERESAPVHLPTILGLKIRAINTTTPAQQGSPQTPTKSKPKIRQATGSNNSNSLLKQQLRGGAKDPEVPPATRITGAVTPNAALNAEEQSKEMPKKNQDEVNACIGLHSLANAAEQQAAQVASTGNLHHQLLLHMAANNSMLNTTDYYQQQQQESPSSAGQFMDDDLELLSLNDQQDKSDEPDHEMVTLADENAGLPGYQGNEAEATPAQEDSPAAETATAPPPAPRSGKKGAKRPIQRRRVRRKAQSTLDDQAEHLTEMSVRGLDLFRYASVVEGVYRCTECAKENMQKTFKNKYSFQRHAFLYHEGKHRKVFPCPVCSKEFSRPDKMKNHLKMTHENFTPPKDIGAFSPLKYLISAAAAGDMHATIYQQQQDHYHRQLAEQLEQQNASFDSRDSSLILPDVKMEHAEDQDAEQEAELSDGGYDASNPAAAAAAMLSLQQDVIIKDEIQISPSPSPTPPASCAVAEGKSLALASTAQTAT | Drosophila melanogaster | Nucleus | Not found | {} | null | {} | [34.0, 32.32, 23.41, 29.75, 28.3, 26.29, 29.3, 28.91, 31.63, 30.32, 29.62, 35.47, 36.27, 39.63, 43.24, 40.22, 39.66, 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P21580 | P21580 | 21095585, E3Net | UbiNet, UbiBrowser, 31181401 | TNFAIP3 | MAEQVLPQALYLSNMRKAVKIRERTPEDIFKPTNGIIHHFKTMHRYTLEMFRTCQFCPQFREIIHKALIDRNIQATLESQKKLNWCREVRKLVALKTNGDGNCLMHATSQYMWGVQDTDLVLRKALFSTLKETDTRNFKFRWQLESLKSQEFVETGLCYDTRNWNDEWDNLIKMASTDTPMARSGLQYNSLEEIHIFVLCNILRRPIIVISDKMLRSLESGSNFAPLKVGGIYLPLHWPAQECYRYPIVLGYDSHHFVPLVTLKDSGPEIRAVPLVNRDRGRFEDLKVHFLTDPENEMKEKLLKEYLMVIEIPVQGWDHGTTHLINAAKLDEANLPKEINLVDDYFELVQHEYKKWQENSEQGRREGHAQNPMEPSVPQLSLMDVKCETPNCPFFMSVNTQPLCHECSERRQKNQNKLPKLNSKPGPEGLPGMALGASRGEAYEPLAWNPEESTGGPHSAPPTAPSPFLFSETTAMKCRSPGCPFTLNVQHNGFCERCHNARQLHASHAPDHTRHLDPGKCQACLQDVTRTFNGICSTCFKRTTAEASSSLSTSLPPSCHQRSKSDPSRLVRSPSPHSCHRAGNDAPAGCLSQAARTPGDRTGTSKCRKAGCVYFGTPENKGFCTLCFIEYRENKHFAAASGKVSPTASRFQNTIPCLGRECGTLGSTMFEGYCQKCFIEAQNQRFHEAKRTEEQLRSSQRRDVPRTTQSTSRPKCARASCKNILACRSEELCMECQHPNQRMGPGAHRGEPAPEDPPKQRCRAPACDHFGNAKCNGYCNECFQFKQMYG | Homo sapiens | Cytoplasm, Nucleus, Lysosome, Cytoplasm | Tissue enhanced (bone marrow, urinary bladder) | {'Ciliated cells': '222.0', 'Basal respiratory cells': '102.4', 'Club cells': '102.0', 'Ionocytes': '151.3', 'Mucus glandular cells': '266.5', 'Serous glandular cells': '115.3', 'Gastric mucus-secreting cells': '78.4', 'Proximal enterocytes': '42.9', 'Paneth cells': '17.5', 'Distal enterocytes': '30.6', 'Intestinal goblet cells': '32.1', 'Exocrine glandular cells': '-0.645', 'Basal prostatic cells': '87.8', 'Prostatic glandular cells': '11.6', 'Breast glandular cells': '0.196', 'Breast myoepithelial cells': '0.372', 'Glandular and luminal cells': '1464.3', 'Secretory cells': '239.6', 'Basal keratinocytes': '563.3', 'Suprabasal keratinocytes': '566.8', 'Basal squamous epithelial cells': '378.1', 'Squamous epithelial cells': '345.1', 'Alveolar cells type 1': '-0.009', 'Alveolar cells type 2': '-0.143', 'Salivary duct cells': '291.9', 'Ductal cells': '0.789', 'Hepatocytes': '0.134', 'Cholangiocytes': '21.0', 'Proximal tubular cells': '0.197', 'Distal tubular cells': '3.1', 'Collecting duct cells': '1.9', 'Mesothelial cells': '0.018', 'Sertoli cells': '0.075', 'Granulosa cells': '40.0', 'Enteroendocrine cells': '18.1', 'Pancreatic endocrine cells': '8.5', 'Leydig cells': '0.370', 'Excitatory neurons': '0.1', 'Inhibitory neurons': '0.3', 'Cone photoreceptor cells': '27.2', 'Rod photoreceptor cells': '15.7', 'Bipolar cells': '0.7', 'Horizontal cells': '1.9', 'Astrocytes': '1.9', 'Oligodendrocyte precursor cells': '1.9', 'Oligodendrocytes': '0.3', 'Microglial cells': '8.1', 'Muller glia cells': '5.5', 'Schwann cells': '0.011', 'Spermatogonia': '0.126', 'Spermatocytes': '-0.024', 'Early spermatids': '-0.035', 'Late spermatids': '-0.353', 'Oocytes': '5.1', 'Cytotrophoblasts': '8.5', 'Syncytiotrophoblasts': '19.6', 'Extravillous trophoblasts': '115.1', 'Endothelial cells': '144.9', 'Lymphatic endothelial cells': '37.6', 'Cardiomyocytes': '0.076', 'Skeletal myocytes': '0.359', 'Smooth muscle cells': '98.4', 'Adipocytes': '63.2', 'Melanocytes': '0.090', 'Fibroblasts': '83.8', 'Peritubular cells': '0.371', 'Endometrial stromal cells': '359.1', 'Ovarian stromal cells': '34.9', 'Undifferentiated cells': '12.6', 'T-cells': '778.2', 'B-cells': '95.4', 'Plasma cells': '280.9', 'Nk-cells': '411.5', 'Granulocytes': '1749.7', 'Monocytes': '1731.0', 'Macrophages': '777.5', 'Hofbauer cells': '176.5', 'Kupffer cells': '128.4', 'Dendritic cells': '129.5', 'Langerhans cells': '0.173', 'Erythroid cells': '0.154', 'Adipocytes (Subcutaneous)': '-0.425', 'Adipocytes (Visceral)': '-0.220', 'Breast glandular cells (progenitors)': '0.080', 'Adipocytes (Breast)': '-0.482', 'Colon enterocytes': '0.003', 'Colon enteroendocrine cells': '0.117', 'Enteric glia cells': '-0.193', 'Mitotic cells (Colon)': '0.097', 'Mitotic cells (Heart)': '0.354', 'Podocytes': '0.203', 'Ascending Loop of Henle cells': '0.015', 'Intercalated cells': '0.035', 'Cholangiocyte': '0.460', 'NK-cells (Liver)': '-0.192', 'Respiratory ciliated cells': '0.038', 'Mitotic cells (Lung)': '-0.111', 'NK-cells (Lung)': '0.178', 'B-cells (Lung)': '0.275', 'Alpha cells': '0.355', 'Beta cells': '0.236', 'Prostate glandular cells': '-0.177', 'Prostate basal glandular cells': '0.085', 'Urothelial cells': '0.154', 'Keratinocyte (other)': '0.355', 'Keratinocyte (granular)': '0.073', 'Hair cortex cells': '-0.229', 'Inner root sheath cells': '-0.173', 'Outer root sheath cells': '-0.203', 'Sebaceous gland cells': '-0.246', 'Eccrine sweat gland cells': '-0.219', 'Adipocytes (Skin)': '-0.360', 'Mitotic cells (Skin)': '0.009', 'Parietal cells': '-0.352', 'Chief cells': '-0.303', 'Gastric mucous cells': '-0.072', 'Gastric enteroendocrine cells': '-0.148', 'Mitotic cells (Stomach)': '0.111', 'Parafollicular cells': '0.005', 'Thyroid glandular cells': '-0.055', 'Mitotic cells (Thyroid)': '0.346', 'Adrenal cortex cells': '0.171', 'Adrenal medulla cells': '-0.001', 'Mitotic cells (Adrenal gland)': '-0.127', 'Minor salivary glandular cells': '0.610', 'Minor salivary gland ductal cells': '0.258', 'Minor salivary gland basal cells': '0.129', 'Mitotic cells (Minor salivary gland)': '0.169', 'Adipocytes (Minor salivary gland)': '0.167', 'Somatotropes': '-0.211', 'Lactotropes': '-0.389', 'Gonadotropes': '0.036', 'Corticotropes': '-0.232', 'Thyrotropes': '-0.083', 'Undifferentiated cells (Pituitary gland)': '0.183', 'Mitotic cells (Spleen)': '-0.149', 'Platelets': '-0.130', 'Erythrocytes': '-0.171', 'Hematopoietic stem cells': '-0.172', 'B-cells (Spleen)': '0.435', 'NK-cells (Spleen)': '0.215', 'Amygdala excitatory': '0.7', 'Cerebellar inhibitory': '2.7', 'Cge interneuron': '0.4', 'Deep-layer corticothalamic and 6b': '0.4', 'Deep-layer intratelencephalic': '0.5', 'Deep-layer near-projecting': '0.1', 'Eccentric medium spiny neuron': '0.5', 'Hippocampal ca1-3': '0.5', 'Hippocampal ca4': '1.3', 'Hippocampal dentate gyrus': '0.5', 'Lamp5-lhx6 and chandelier': '0.9', 'Lower rhombic lip': '1.3', 'Mammillary body': '0.2', 'Medium spiny neuron': '0.4', 'Mge interneuron': '0.1', 'Midbrain-derived inhibitory': '0.0', 'Miscellaneous': '0.2', 'Splatter': '1.2', 'Thalamic excitatory': '2.3', 'Upper rhombic lip': '0.1', 'Upper-layer intratelencephalic': '0.6', 'Astrocyte': '3.0', 'Bergmann glia': '2.5', 'Central nervous system macrophage': '24.4', 'Choroid plexus epithelial cell': '0.7', 'Committed oligodendrocyte precursor': '1.6', 'Ependymal cell': '2.1', 'Oligodendrocyte': '0.7', 'Oligodendrocyte precursor cell': '2.0', 'Endothelial cell': '51.5', 'Pericyte': '15.8', 'Vascular associated smooth muscle cell': '12.1', 'Fibroblast': '17.8', 'Leukocyte': '94.2', 'Basophil': '92.3', 'Eosinophil': '5.6', 'Neutrophil': '3039.7', 'Classical monocyte': '535.9', 'Non-classical monocyte': '75.6', 'Intermediate monocyte': '1330.1', 'T-reg': '572.8', 'GdT-cell': '11.5', 'MAIT T-cell': '1817.4', 'Memory CD4 T-cell': '11.1', 'Naive CD4 T-cell': '1624.2', 'Memory CD8 T-cell': '10.9', 'Naive CD8 T-cell': '1289.0', 'Memory B-cell': '4.6', 'Naive B-cell': '193.4', 'Plasmacytoid DC': '146.7', 'Myeloid DC': '771.0', 'NK-cell': '630.7', 'Total PBMC': '438.1', 'Vd2 gdTCR': '1321.8', 'Memory CD4 T-cell Th1\\/Th17': '4758.2', 'Memory CD4 T-cell Th17': '2777.6', 'Memory CD4 T-cell Th2': '2696.4', 'Non-Vd2 gdTCR': '697.3', 'Memory CD4 T-cell Th1': '3101.6', 'Memory CD4 T-cell TFH': '1767.2', 'Terminal effector memory CD4 T-cell': '586.0', 'Central memory CD8 T-cell': '1346.2', 'Effector memory CD8 T-cell': '1030.8', 'Terminal effector memory CD8 T-cell': '643.9', 'Non-switched memory B-cell': '183.3', 'Plasmablast': '108.3', 'Switched memory B-cell': '133.9', 'Exhausted memory B-cell': '184.7', 'Progenitor cell': '61.7', 'Memory T-reg': '1316.7', 'Naive CD4 T-cell activated': '1454.6', 'Naive CD8 T-cell activated': '1341.5', 'Naive T-reg': '813.0'} | 2EQE, 2EQF, 2EQG, 2VFJ, 3DKB, 3OJ3, 3OJ4, 3VUW, 3VUX, 3VUY, 3ZJD, 3ZJE, 3ZJF, 3ZJG, 5LRX, 5V3B, 5V3P | {'Adipose Tissue': 71.89422425249168, 'Adrenal Gland': 18.808178294573644, 'Bladder': 27.82095238095238, 'Blood': 90.27551883745964, 'Blood Vessel': 22.304372284644195, 'Brain': 2.4634945495836487, 'Breast': 38.57104575163399, 'Cervix Uteri': 22.62152631578947, 'Colon': 29.911654685494224, 'Esophagus': 23.34145743944637, 'Fallopian Tube': 47.24111111111111, 'Heart': 12.724618118466898, 'Kidney': 16.023370786516853, 'Liver': 11.73166814159292, 'Lung': 103.90608996539792, 'Muscle': 5.374799252801993, 'Nerve': 35.55016155088853, 'Ovary': 131.08455555555557, 'Pancreas': 9.580134146341464, 'Pituitary': 13.757773851590104, 'Prostate': 30.354032653061225, 'Salivary Gland': 23.303753086419754, 'Skin': 55.29272028745163, 'Small Intestine': 50.19026737967914, 'Spleen': 57.31813278008299, 'Stomach': 21.495189415041786, 'Testis': 14.136614958448757, 'Thyroid': 23.792597243491574, 'Uterus': 30.784436619718313, 'Vagina': 27.45127564102564} | TNFAIP3 | MAEQVLPQALYLSNMRKAVKIRERTPEDIFKPTNGIIHHFKTMHRYTLEMFRTCQFCPQFREIIHKALIDRNIQATLESQKKLNWCREVRKLVALKTNGDGNCLMHATSQYMWGVQDTDLVLRKALFSTLKETDTRNFKFRWQLESLKSQEFVETGLCYDTRNWNDEWDNLIKMASTDTPMARSGLQYNSLEEIHIFVLCNILRRPIIVISDKMLRSLESGSNFAPLKVGGIYLPLHWPAQECYRYPIVLGYDSHHFVPLVTLKDSGPEIRAVPLVNRDRGRFEDLKVHFLTDPENEMKEKLLKEYLMVIEIPVQGWDHGTTHLINAAKLDEANLPKEINLVDDYFELVQHEYKKWQENSEQGRREGHAQNPMEPSVPQLSLMDVKCETPNCPFFMSVNTQPLCHECSERRQKNQNKLPKLNSKPGPEGLPGMALGASRGEAYEPLAWNPEESTGGPHSAPPTAPSPFLFSETTAMKCRSPGCPFTLNVQHNGFCERCHNARQLHASHAPDHTRHLDPGKCQACLQDVTRTFNGICSTCFKRTTAEASSSLSTSLPPSCHQRSKSDPSRLVRSPSPHSCHRAGNDAPAGCLSQAARTPGDRTGTSKCRKAGCVYFGTPENKGFCTLCFIEYRENKHFAAASGKVSPTASRFQNTIPCLGRECGTLGSTMFEGYCQKCFIEAQNQRFHEAKRTEEQLRSSQRRDVPRTTQSTSRPKCARASCKNILACRSEELCMECQHPNQRMGPGAHRGEPAPEDPPKQRCRAPACDHFGNAKCNGYCNECFQFKQMYG | Homo sapiens | Cytoplasm, Nucleus, Lysosome, Cytoplasm | Tissue enhanced (bone marrow, urinary bladder) | {'Ciliated cells': '222.0', 'Basal respiratory cells': '102.4', 'Club cells': '102.0', 'Ionocytes': '151.3', 'Mucus glandular cells': '266.5', 'Serous glandular cells': '115.3', 'Gastric mucus-secreting cells': '78.4', 'Proximal enterocytes': '42.9', 'Paneth cells': '17.5', 'Distal enterocytes': '30.6', 'Intestinal goblet cells': '32.1', 'Exocrine glandular cells': '-0.645', 'Basal prostatic cells': '87.8', 'Prostatic glandular cells': '11.6', 'Breast glandular cells': '0.196', 'Breast myoepithelial cells': '0.372', 'Glandular and luminal cells': '1464.3', 'Secretory cells': '239.6', 'Basal keratinocytes': '563.3', 'Suprabasal keratinocytes': '566.8', 'Basal squamous epithelial cells': '378.1', 'Squamous epithelial cells': '345.1', 'Alveolar cells type 1': '-0.009', 'Alveolar cells type 2': '-0.143', 'Salivary duct cells': '291.9', 'Ductal cells': '0.789', 'Hepatocytes': '0.134', 'Cholangiocytes': '21.0', 'Proximal tubular cells': '0.197', 'Distal tubular cells': '3.1', 'Collecting duct cells': '1.9', 'Mesothelial cells': '0.018', 'Sertoli cells': '0.075', 'Granulosa cells': '40.0', 'Enteroendocrine cells': '18.1', 'Pancreatic endocrine cells': '8.5', 'Leydig cells': '0.370', 'Excitatory neurons': '0.1', 'Inhibitory neurons': '0.3', 'Cone photoreceptor cells': '27.2', 'Rod photoreceptor cells': '15.7', 'Bipolar cells': '0.7', 'Horizontal cells': '1.9', 'Astrocytes': '1.9', 'Oligodendrocyte precursor cells': '1.9', 'Oligodendrocytes': '0.3', 'Microglial cells': '8.1', 'Muller glia cells': '5.5', 'Schwann cells': '0.011', 'Spermatogonia': '0.126', 'Spermatocytes': '-0.024', 'Early spermatids': '-0.035', 'Late spermatids': '-0.353', 'Oocytes': '5.1', 'Cytotrophoblasts': '8.5', 'Syncytiotrophoblasts': '19.6', 'Extravillous trophoblasts': '115.1', 'Endothelial cells': '144.9', 'Lymphatic endothelial cells': '37.6', 'Cardiomyocytes': '0.076', 'Skeletal myocytes': '0.359', 'Smooth muscle cells': '98.4', 'Adipocytes': '63.2', 'Melanocytes': '0.090', 'Fibroblasts': '83.8', 'Peritubular cells': '0.371', 'Endometrial stromal cells': '359.1', 'Ovarian stromal cells': '34.9', 'Undifferentiated cells': '12.6', 'T-cells': '778.2', 'B-cells': '95.4', 'Plasma cells': '280.9', 'Nk-cells': '411.5', 'Granulocytes': '1749.7', 'Monocytes': '1731.0', 'Macrophages': '777.5', 'Hofbauer cells': '176.5', 'Kupffer cells': '128.4', 'Dendritic cells': '129.5', 'Langerhans cells': '0.173', 'Erythroid cells': '0.154', 'Adipocytes (Subcutaneous)': '-0.425', 'Adipocytes (Visceral)': '-0.220', 'Breast glandular cells (progenitors)': '0.080', 'Adipocytes (Breast)': '-0.482', 'Colon enterocytes': '0.003', 'Colon enteroendocrine cells': '0.117', 'Enteric glia cells': '-0.193', 'Mitotic cells (Colon)': '0.097', 'Mitotic cells (Heart)': '0.354', 'Podocytes': '0.203', 'Ascending Loop of Henle cells': '0.015', 'Intercalated cells': '0.035', 'Cholangiocyte': '0.460', 'NK-cells (Liver)': '-0.192', 'Respiratory ciliated cells': '0.038', 'Mitotic cells (Lung)': '-0.111', 'NK-cells (Lung)': '0.178', 'B-cells (Lung)': '0.275', 'Alpha cells': '0.355', 'Beta cells': '0.236', 'Prostate glandular cells': '-0.177', 'Prostate basal glandular cells': '0.085', 'Urothelial cells': '0.154', 'Keratinocyte (other)': '0.355', 'Keratinocyte (granular)': '0.073', 'Hair cortex cells': '-0.229', 'Inner root sheath cells': '-0.173', 'Outer root sheath cells': '-0.203', 'Sebaceous gland cells': '-0.246', 'Eccrine sweat gland cells': '-0.219', 'Adipocytes (Skin)': '-0.360', 'Mitotic cells (Skin)': '0.009', 'Parietal cells': '-0.352', 'Chief cells': '-0.303', 'Gastric mucous cells': '-0.072', 'Gastric enteroendocrine cells': '-0.148', 'Mitotic cells (Stomach)': '0.111', 'Parafollicular cells': '0.005', 'Thyroid glandular cells': '-0.055', 'Mitotic cells (Thyroid)': '0.346', 'Adrenal cortex cells': '0.171', 'Adrenal medulla cells': '-0.001', 'Mitotic cells (Adrenal gland)': '-0.127', 'Minor salivary glandular cells': '0.610', 'Minor salivary gland ductal cells': '0.258', 'Minor salivary gland basal cells': '0.129', 'Mitotic cells (Minor salivary gland)': '0.169', 'Adipocytes (Minor 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| null | UBE2N, UBE2D3 | Homodimer | null | 74.507911 | 0.508165 | 74.507911 | 0.508165 | 818 |
P21580 | Q13546 | 15258597, TNAP3_HUMAN, BioGrid E3Net | UbiNet, UbiBrowser, 31181401 | TNFAIP3 | MAEQVLPQALYLSNMRKAVKIRERTPEDIFKPTNGIIHHFKTMHRYTLEMFRTCQFCPQFREIIHKALIDRNIQATLESQKKLNWCREVRKLVALKTNGDGNCLMHATSQYMWGVQDTDLVLRKALFSTLKETDTRNFKFRWQLESLKSQEFVETGLCYDTRNWNDEWDNLIKMASTDTPMARSGLQYNSLEEIHIFVLCNILRRPIIVISDKMLRSLESGSNFAPLKVGGIYLPLHWPAQECYRYPIVLGYDSHHFVPLVTLKDSGPEIRAVPLVNRDRGRFEDLKVHFLTDPENEMKEKLLKEYLMVIEIPVQGWDHGTTHLINAAKLDEANLPKEINLVDDYFELVQHEYKKWQENSEQGRREGHAQNPMEPSVPQLSLMDVKCETPNCPFFMSVNTQPLCHECSERRQKNQNKLPKLNSKPGPEGLPGMALGASRGEAYEPLAWNPEESTGGPHSAPPTAPSPFLFSETTAMKCRSPGCPFTLNVQHNGFCERCHNARQLHASHAPDHTRHLDPGKCQACLQDVTRTFNGICSTCFKRTTAEASSSLSTSLPPSCHQRSKSDPSRLVRSPSPHSCHRAGNDAPAGCLSQAARTPGDRTGTSKCRKAGCVYFGTPENKGFCTLCFIEYRENKHFAAASGKVSPTASRFQNTIPCLGRECGTLGSTMFEGYCQKCFIEAQNQRFHEAKRTEEQLRSSQRRDVPRTTQSTSRPKCARASCKNILACRSEELCMECQHPNQRMGPGAHRGEPAPEDPPKQRCRAPACDHFGNAKCNGYCNECFQFKQMYG | Homo sapiens | Cytoplasm, Nucleus, Lysosome, Cytoplasm | Tissue enhanced (bone marrow, urinary bladder) | {'Ciliated cells': '222.0', 'Basal respiratory cells': '102.4', 'Club cells': '102.0', 'Ionocytes': '151.3', 'Mucus glandular cells': '266.5', 'Serous glandular cells': '115.3', 'Gastric mucus-secreting cells': '78.4', 'Proximal enterocytes': '42.9', 'Paneth cells': '17.5', 'Distal enterocytes': '30.6', 'Intestinal goblet cells': '32.1', 'Exocrine glandular cells': '-0.645', 'Basal prostatic cells': '87.8', 'Prostatic glandular cells': '11.6', 'Breast glandular cells': '0.196', 'Breast myoepithelial cells': '0.372', 'Glandular and luminal cells': '1464.3', 'Secretory cells': '239.6', 'Basal keratinocytes': '563.3', 'Suprabasal keratinocytes': '566.8', 'Basal squamous epithelial cells': '378.1', 'Squamous epithelial cells': '345.1', 'Alveolar cells type 1': '-0.009', 'Alveolar cells type 2': '-0.143', 'Salivary duct cells': '291.9', 'Ductal cells': '0.789', 'Hepatocytes': '0.134', 'Cholangiocytes': '21.0', 'Proximal tubular cells': '0.197', 'Distal tubular cells': '3.1', 'Collecting duct cells': '1.9', 'Mesothelial cells': '0.018', 'Sertoli cells': '0.075', 'Granulosa cells': '40.0', 'Enteroendocrine cells': '18.1', 'Pancreatic endocrine cells': '8.5', 'Leydig cells': '0.370', 'Excitatory neurons': '0.1', 'Inhibitory neurons': '0.3', 'Cone photoreceptor cells': '27.2', 'Rod photoreceptor cells': '15.7', 'Bipolar cells': '0.7', 'Horizontal cells': '1.9', 'Astrocytes': '1.9', 'Oligodendrocyte precursor cells': '1.9', 'Oligodendrocytes': '0.3', 'Microglial cells': '8.1', 'Muller glia cells': '5.5', 'Schwann cells': '0.011', 'Spermatogonia': '0.126', 'Spermatocytes': '-0.024', 'Early spermatids': '-0.035', 'Late spermatids': '-0.353', 'Oocytes': '5.1', 'Cytotrophoblasts': '8.5', 'Syncytiotrophoblasts': '19.6', 'Extravillous trophoblasts': '115.1', 'Endothelial cells': '144.9', 'Lymphatic endothelial cells': '37.6', 'Cardiomyocytes': '0.076', 'Skeletal myocytes': '0.359', 'Smooth muscle cells': '98.4', 'Adipocytes': '63.2', 'Melanocytes': '0.090', 'Fibroblasts': '83.8', 'Peritubular cells': '0.371', 'Endometrial stromal cells': '359.1', 'Ovarian stromal cells': '34.9', 'Undifferentiated cells': '12.6', 'T-cells': '778.2', 'B-cells': '95.4', 'Plasma cells': '280.9', 'Nk-cells': '411.5', 'Granulocytes': '1749.7', 'Monocytes': '1731.0', 'Macrophages': '777.5', 'Hofbauer cells': '176.5', 'Kupffer cells': '128.4', 'Dendritic cells': '129.5', 'Langerhans cells': '0.173', 'Erythroid cells': '0.154', 'Adipocytes (Subcutaneous)': '-0.425', 'Adipocytes (Visceral)': '-0.220', 'Breast glandular cells (progenitors)': '0.080', 'Adipocytes (Breast)': '-0.482', 'Colon enterocytes': '0.003', 'Colon enteroendocrine cells': '0.117', 'Enteric glia cells': '-0.193', 'Mitotic cells (Colon)': '0.097', 'Mitotic cells (Heart)': '0.354', 'Podocytes': '0.203', 'Ascending Loop of Henle cells': '0.015', 'Intercalated cells': '0.035', 'Cholangiocyte': '0.460', 'NK-cells (Liver)': '-0.192', 'Respiratory ciliated cells': '0.038', 'Mitotic cells (Lung)': '-0.111', 'NK-cells (Lung)': '0.178', 'B-cells (Lung)': '0.275', 'Alpha cells': '0.355', 'Beta cells': '0.236', 'Prostate glandular cells': '-0.177', 'Prostate basal glandular cells': '0.085', 'Urothelial cells': '0.154', 'Keratinocyte (other)': '0.355', 'Keratinocyte (granular)': '0.073', 'Hair cortex cells': '-0.229', 'Inner root sheath cells': '-0.173', 'Outer root sheath cells': '-0.203', 'Sebaceous gland cells': '-0.246', 'Eccrine sweat gland cells': '-0.219', 'Adipocytes (Skin)': '-0.360', 'Mitotic cells (Skin)': '0.009', 'Parietal cells': '-0.352', 'Chief cells': '-0.303', 'Gastric mucous cells': '-0.072', 'Gastric enteroendocrine cells': '-0.148', 'Mitotic cells (Stomach)': '0.111', 'Parafollicular cells': '0.005', 'Thyroid glandular cells': '-0.055', 'Mitotic cells (Thyroid)': '0.346', 'Adrenal cortex cells': '0.171', 'Adrenal medulla cells': '-0.001', 'Mitotic cells (Adrenal gland)': '-0.127', 'Minor salivary glandular cells': '0.610', 'Minor salivary gland ductal cells': '0.258', 'Minor salivary gland basal cells': '0.129', 'Mitotic cells (Minor salivary gland)': '0.169', 'Adipocytes (Minor salivary gland)': '0.167', 'Somatotropes': '-0.211', 'Lactotropes': '-0.389', 'Gonadotropes': '0.036', 'Corticotropes': '-0.232', 'Thyrotropes': '-0.083', 'Undifferentiated cells (Pituitary gland)': '0.183', 'Mitotic cells (Spleen)': '-0.149', 'Platelets': '-0.130', 'Erythrocytes': '-0.171', 'Hematopoietic stem cells': '-0.172', 'B-cells (Spleen)': '0.435', 'NK-cells (Spleen)': '0.215', 'Amygdala excitatory': '0.7', 'Cerebellar inhibitory': '2.7', 'Cge interneuron': '0.4', 'Deep-layer corticothalamic and 6b': '0.4', 'Deep-layer intratelencephalic': '0.5', 'Deep-layer near-projecting': '0.1', 'Eccentric medium spiny neuron': '0.5', 'Hippocampal ca1-3': '0.5', 'Hippocampal ca4': '1.3', 'Hippocampal dentate gyrus': '0.5', 'Lamp5-lhx6 and chandelier': '0.9', 'Lower rhombic lip': '1.3', 'Mammillary body': '0.2', 'Medium spiny neuron': '0.4', 'Mge interneuron': '0.1', 'Midbrain-derived inhibitory': '0.0', 'Miscellaneous': '0.2', 'Splatter': '1.2', 'Thalamic excitatory': '2.3', 'Upper rhombic lip': '0.1', 'Upper-layer intratelencephalic': '0.6', 'Astrocyte': '3.0', 'Bergmann glia': '2.5', 'Central nervous system macrophage': '24.4', 'Choroid plexus epithelial cell': '0.7', 'Committed oligodendrocyte precursor': '1.6', 'Ependymal cell': '2.1', 'Oligodendrocyte': '0.7', 'Oligodendrocyte precursor cell': '2.0', 'Endothelial cell': '51.5', 'Pericyte': '15.8', 'Vascular associated smooth muscle cell': '12.1', 'Fibroblast': '17.8', 'Leukocyte': '94.2', 'Basophil': '92.3', 'Eosinophil': '5.6', 'Neutrophil': '3039.7', 'Classical monocyte': '535.9', 'Non-classical monocyte': '75.6', 'Intermediate monocyte': '1330.1', 'T-reg': '572.8', 'GdT-cell': '11.5', 'MAIT T-cell': '1817.4', 'Memory CD4 T-cell': '11.1', 'Naive CD4 T-cell': '1624.2', 'Memory CD8 T-cell': '10.9', 'Naive CD8 T-cell': '1289.0', 'Memory B-cell': '4.6', 'Naive B-cell': '193.4', 'Plasmacytoid DC': '146.7', 'Myeloid DC': '771.0', 'NK-cell': '630.7', 'Total PBMC': '438.1', 'Vd2 gdTCR': '1321.8', 'Memory CD4 T-cell Th1\\/Th17': '4758.2', 'Memory CD4 T-cell Th17': '2777.6', 'Memory CD4 T-cell Th2': '2696.4', 'Non-Vd2 gdTCR': '697.3', 'Memory CD4 T-cell Th1': '3101.6', 'Memory CD4 T-cell TFH': '1767.2', 'Terminal effector memory CD4 T-cell': '586.0', 'Central memory CD8 T-cell': '1346.2', 'Effector memory CD8 T-cell': '1030.8', 'Terminal effector memory CD8 T-cell': '643.9', 'Non-switched memory B-cell': '183.3', 'Plasmablast': '108.3', 'Switched memory B-cell': '133.9', 'Exhausted memory B-cell': '184.7', 'Progenitor cell': '61.7', 'Memory T-reg': '1316.7', 'Naive CD4 T-cell activated': '1454.6', 'Naive CD8 T-cell activated': '1341.5', 'Naive T-reg': '813.0'} | 2EQE, 2EQF, 2EQG, 2VFJ, 3DKB, 3OJ3, 3OJ4, 3VUW, 3VUX, 3VUY, 3ZJD, 3ZJE, 3ZJF, 3ZJG, 5LRX, 5V3B, 5V3P | {'Adipose Tissue': 71.89422425249168, 'Adrenal Gland': 18.808178294573644, 'Bladder': 27.82095238095238, 'Blood': 90.27551883745964, 'Blood Vessel': 22.304372284644195, 'Brain': 2.4634945495836487, 'Breast': 38.57104575163399, 'Cervix Uteri': 22.62152631578947, 'Colon': 29.911654685494224, 'Esophagus': 23.34145743944637, 'Fallopian Tube': 47.24111111111111, 'Heart': 12.724618118466898, 'Kidney': 16.023370786516853, 'Liver': 11.73166814159292, 'Lung': 103.90608996539792, 'Muscle': 5.374799252801993, 'Nerve': 35.55016155088853, 'Ovary': 131.08455555555557, 'Pancreas': 9.580134146341464, 'Pituitary': 13.757773851590104, 'Prostate': 30.354032653061225, 'Salivary Gland': 23.303753086419754, 'Skin': 55.29272028745163, 'Small Intestine': 50.19026737967914, 'Spleen': 57.31813278008299, 'Stomach': 21.495189415041786, 'Testis': 14.136614958448757, 'Thyroid': 23.792597243491574, 'Uterus': 30.784436619718313, 'Vagina': 27.45127564102564} | RIPK1 | MQPDMSLNVIKMKSSDFLESAELDSGGFGKVSLCFHRTQGLMIMKTVYKGPNCIEHNEALLEEAKMMNRLRHSRVVKLLGVIIEEGKYSLVMEYMEKGNLMHVLKAEMSTPLSVKGRIILEIIEGMCYLHGKGVIHKDLKPENILVDNDFHIKIADLGLASFKMWSKLNNEEHNELREVDGTAKKNGGTLYYMAPEHLNDVNAKPTEKSDVYSFAVVLWAIFANKEPYENAICEQQLIMCIKSGNRPDVDDITEYCPREIISLMKLCWEANPEARPTFPGIEEKFRPFYLSQLEESVEEDVKSLKKEYSNENAVVKRMQSLQLDCVAVPSSRSNSATEQPGSLHSSQGLGMGPVEESWFAPSLEHPQEENEPSLQSKLQDEANYHLYGSRMDRQTKQQPRQNVAYNREEERRRRVSHDPFAQQRPYENFQNTEGKGTAYSSAASHGNAVHQPSGLTSQPQVLYQNNGLYSSHGFGTRPLDPGTAGPRVWYRPIPSHMPSLHNIPVPETNYLGNTPTMPFSSLPPTDESIKYTIYNSTGIQIGAYNYMEIGGTSSSLLDSTNTNFKEEPAAKYQAIFDNTTSLTDKHLDPIRENLGKHWKNCARKLGFTQSQIDEIDHDYERDGLKEKVYQMLQKWVMREGIKGATVGKLAQALHQCSRIDLLSSLIYVSQN | Homo sapiens | Cytoplasm, Cell membrane | Low tissue specificity | {'Ciliated cells': '15.7', 'Basal respiratory cells': '10.3', 'Club cells': '17.3', 'Ionocytes': '18.4', 'Mucus glandular cells': '27.3', 'Serous glandular cells': '21.2', 'Gastric mucus-secreting cells': '42.4', 'Proximal enterocytes': '28.4', 'Paneth cells': '17.2', 'Distal enterocytes': '27.0', 'Intestinal goblet cells': '24.0', 'Exocrine glandular cells': '-0.692', 'Basal prostatic cells': '24.2', 'Prostatic glandular cells': '18.7', 'Breast glandular cells': '0.125', 'Breast myoepithelial cells': '-0.063', 'Glandular and luminal cells': '19.3', 'Secretory cells': '23.0', 'Basal keratinocytes': '18.6', 'Suprabasal keratinocytes': '19.4', 'Basal squamous epithelial cells': '23.3', 'Squamous epithelial cells': '32.1', 'Alveolar cells type 1': '0.124', 'Alveolar cells type 2': '0.272', 'Salivary duct cells': '31.2', 'Ductal cells': '0.588', 'Hepatocytes': '0.304', 'Cholangiocytes': '15.3', 'Proximal tubular cells': '0.217', 'Distal tubular cells': '6.1', 'Collecting duct cells': '15.6', 'Mesothelial cells': '-0.059', 'Sertoli cells': '0.537', 'Granulosa cells': '17.4', 'Enteroendocrine cells': '14.5', 'Pancreatic endocrine cells': '11.9', 'Leydig cells': '0.668', 'Excitatory neurons': '22.3', 'Inhibitory neurons': '25.6', 'Cone photoreceptor cells': '10.2', 'Rod photoreceptor cells': '35.7', 'Bipolar cells': '7.3', 'Horizontal cells': '7.6', 'Astrocytes': '16.4', 'Oligodendrocyte precursor cells': '13.7', 'Oligodendrocytes': '15.1', 'Microglial cells': '10.7', 'Muller glia cells': '11.1', 'Schwann cells': '0.170', 'Spermatogonia': '0.404', 'Spermatocytes': '0.061', 'Early spermatids': '-0.525', 'Late spermatids': '-0.695', 'Oocytes': '2.2', 'Cytotrophoblasts': '10.6', 'Syncytiotrophoblasts': '14.6', 'Extravillous trophoblasts': '9.3', 'Endothelial cells': '25.7', 'Lymphatic endothelial cells': '28.0', 'Cardiomyocytes': '0.368', 'Skeletal myocytes': '-0.331', 'Smooth muscle cells': '26.3', 'Adipocytes': '39.9', 'Melanocytes': '0.001', 'Fibroblasts': '22.3', 'Peritubular cells': '0.544', 'Endometrial stromal cells': '19.4', 'Ovarian stromal cells': '6.2', 'Undifferentiated cells': '11.9', 'T-cells': '29.5', 'B-cells': '19.4', 'Plasma cells': '26.1', 'Nk-cells': '32.1', 'Granulocytes': '23.0', 'Monocytes': '39.9', 'Macrophages': '28.5', 'Hofbauer cells': '14.8', 'Kupffer cells': '10.3', 'Dendritic cells': '37.8', 'Langerhans cells': '0.240', 'Erythroid cells': '-0.128', 'Adipocytes (Subcutaneous)': '0.241', 'Adipocytes (Visceral)': '0.313', 'Breast glandular cells (progenitors)': '0.025', 'Adipocytes (Breast)': '0.172', 'Colon enterocytes': '0.036', 'Colon enteroendocrine cells': '0.103', 'Enteric glia cells': '-0.286', 'Mitotic cells (Colon)': '0.070', 'Mitotic cells (Heart)': '0.464', 'Podocytes': '-0.198', 'Ascending Loop of Henle cells': '0.303', 'Intercalated cells': '-0.119', 'Cholangiocyte': '0.211', 'NK-cells (Liver)': '-0.222', 'Respiratory ciliated cells': '-0.078', 'Mitotic cells (Lung)': '0.046', 'NK-cells (Lung)': '-0.097', 'B-cells (Lung)': '-0.216', 'Alpha cells': '0.304', 'Beta cells': '0.195', 'Prostate glandular cells': '-0.100', 'Prostate basal glandular cells': '0.318', 'Urothelial cells': '0.252', 'Keratinocyte (other)': '0.244', 'Keratinocyte (granular)': '0.292', 'Hair cortex cells': '-0.248', 'Inner root sheath cells': '-0.269', 'Outer root sheath cells': '-0.289', 'Sebaceous gland cells': '0.026', 'Eccrine sweat gland cells': '-0.246', 'Adipocytes (Skin)': '-0.149', 'Mitotic cells (Skin)': '-0.226', 'Parietal cells': '-0.446', 'Chief cells': '-0.419', 'Gastric mucous cells': '-0.130', 'Gastric enteroendocrine cells': '-0.296', 'Mitotic cells (Stomach)': '0.183', 'Parafollicular cells': '-0.018', 'Thyroid glandular cells': '0.350', 'Mitotic cells (Thyroid)': '-0.021', 'Adrenal cortex cells': '0.496', 'Adrenal medulla cells': '0.137', 'Mitotic cells (Adrenal gland)': '0.311', 'Minor salivary glandular cells': '0.542', 'Minor salivary gland ductal cells': '0.199', 'Minor salivary gland basal cells': '0.307', 'Mitotic cells (Minor salivary gland)': '0.248', 'Adipocytes (Minor salivary gland)': '0.156', 'Somatotropes': '-0.031', 'Lactotropes': '-0.046', 'Gonadotropes': '0.007', 'Corticotropes': '-0.042', 'Thyrotropes': '-0.011', 'Undifferentiated 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P21580 | Q9H4P4 | 34023381 | UbiBrowser | TNFAIP3 | MAEQVLPQALYLSNMRKAVKIRERTPEDIFKPTNGIIHHFKTMHRYTLEMFRTCQFCPQFREIIHKALIDRNIQATLESQKKLNWCREVRKLVALKTNGDGNCLMHATSQYMWGVQDTDLVLRKALFSTLKETDTRNFKFRWQLESLKSQEFVETGLCYDTRNWNDEWDNLIKMASTDTPMARSGLQYNSLEEIHIFVLCNILRRPIIVISDKMLRSLESGSNFAPLKVGGIYLPLHWPAQECYRYPIVLGYDSHHFVPLVTLKDSGPEIRAVPLVNRDRGRFEDLKVHFLTDPENEMKEKLLKEYLMVIEIPVQGWDHGTTHLINAAKLDEANLPKEINLVDDYFELVQHEYKKWQENSEQGRREGHAQNPMEPSVPQLSLMDVKCETPNCPFFMSVNTQPLCHECSERRQKNQNKLPKLNSKPGPEGLPGMALGASRGEAYEPLAWNPEESTGGPHSAPPTAPSPFLFSETTAMKCRSPGCPFTLNVQHNGFCERCHNARQLHASHAPDHTRHLDPGKCQACLQDVTRTFNGICSTCFKRTTAEASSSLSTSLPPSCHQRSKSDPSRLVRSPSPHSCHRAGNDAPAGCLSQAARTPGDRTGTSKCRKAGCVYFGTPENKGFCTLCFIEYRENKHFAAASGKVSPTASRFQNTIPCLGRECGTLGSTMFEGYCQKCFIEAQNQRFHEAKRTEEQLRSSQRRDVPRTTQSTSRPKCARASCKNILACRSEELCMECQHPNQRMGPGAHRGEPAPEDPPKQRCRAPACDHFGNAKCNGYCNECFQFKQMYG | Homo sapiens | Cytoplasm, Nucleus, Lysosome, Cytoplasm | Tissue enhanced (bone marrow, urinary bladder) | {'Ciliated cells': '222.0', 'Basal respiratory cells': '102.4', 'Club cells': '102.0', 'Ionocytes': '151.3', 'Mucus glandular cells': '266.5', 'Serous glandular cells': '115.3', 'Gastric mucus-secreting cells': '78.4', 'Proximal enterocytes': '42.9', 'Paneth cells': '17.5', 'Distal enterocytes': '30.6', 'Intestinal goblet cells': '32.1', 'Exocrine glandular cells': '-0.645', 'Basal prostatic cells': '87.8', 'Prostatic glandular cells': '11.6', 'Breast glandular cells': '0.196', 'Breast myoepithelial cells': '0.372', 'Glandular and luminal cells': '1464.3', 'Secretory cells': '239.6', 'Basal keratinocytes': '563.3', 'Suprabasal keratinocytes': '566.8', 'Basal squamous epithelial cells': '378.1', 'Squamous epithelial cells': '345.1', 'Alveolar cells type 1': '-0.009', 'Alveolar cells type 2': '-0.143', 'Salivary duct cells': '291.9', 'Ductal cells': '0.789', 'Hepatocytes': '0.134', 'Cholangiocytes': '21.0', 'Proximal tubular cells': '0.197', 'Distal tubular cells': '3.1', 'Collecting duct cells': '1.9', 'Mesothelial cells': '0.018', 'Sertoli cells': '0.075', 'Granulosa cells': '40.0', 'Enteroendocrine cells': '18.1', 'Pancreatic endocrine cells': '8.5', 'Leydig cells': '0.370', 'Excitatory neurons': '0.1', 'Inhibitory neurons': '0.3', 'Cone photoreceptor cells': '27.2', 'Rod photoreceptor cells': '15.7', 'Bipolar cells': '0.7', 'Horizontal cells': '1.9', 'Astrocytes': '1.9', 'Oligodendrocyte precursor cells': '1.9', 'Oligodendrocytes': '0.3', 'Microglial cells': '8.1', 'Muller glia cells': '5.5', 'Schwann cells': '0.011', 'Spermatogonia': '0.126', 'Spermatocytes': '-0.024', 'Early spermatids': '-0.035', 'Late spermatids': '-0.353', 'Oocytes': '5.1', 'Cytotrophoblasts': '8.5', 'Syncytiotrophoblasts': '19.6', 'Extravillous trophoblasts': '115.1', 'Endothelial cells': '144.9', 'Lymphatic endothelial cells': '37.6', 'Cardiomyocytes': '0.076', 'Skeletal myocytes': '0.359', 'Smooth muscle cells': '98.4', 'Adipocytes': '63.2', 'Melanocytes': '0.090', 'Fibroblasts': '83.8', 'Peritubular cells': '0.371', 'Endometrial stromal cells': '359.1', 'Ovarian stromal cells': '34.9', 'Undifferentiated cells': '12.6', 'T-cells': '778.2', 'B-cells': '95.4', 'Plasma cells': '280.9', 'Nk-cells': '411.5', 'Granulocytes': '1749.7', 'Monocytes': '1731.0', 'Macrophages': '777.5', 'Hofbauer cells': '176.5', 'Kupffer cells': '128.4', 'Dendritic cells': '129.5', 'Langerhans cells': '0.173', 'Erythroid cells': '0.154', 'Adipocytes (Subcutaneous)': '-0.425', 'Adipocytes (Visceral)': '-0.220', 'Breast glandular cells (progenitors)': '0.080', 'Adipocytes (Breast)': '-0.482', 'Colon enterocytes': '0.003', 'Colon enteroendocrine cells': '0.117', 'Enteric glia cells': '-0.193', 'Mitotic cells (Colon)': '0.097', 'Mitotic cells (Heart)': '0.354', 'Podocytes': '0.203', 'Ascending Loop of Henle cells': '0.015', 'Intercalated cells': '0.035', 'Cholangiocyte': '0.460', 'NK-cells (Liver)': '-0.192', 'Respiratory ciliated cells': '0.038', 'Mitotic cells (Lung)': '-0.111', 'NK-cells (Lung)': '0.178', 'B-cells (Lung)': '0.275', 'Alpha cells': '0.355', 'Beta cells': '0.236', 'Prostate glandular cells': '-0.177', 'Prostate basal glandular cells': '0.085', 'Urothelial cells': '0.154', 'Keratinocyte (other)': '0.355', 'Keratinocyte (granular)': '0.073', 'Hair cortex cells': '-0.229', 'Inner root sheath cells': '-0.173', 'Outer root sheath cells': '-0.203', 'Sebaceous gland cells': '-0.246', 'Eccrine sweat gland cells': '-0.219', 'Adipocytes (Skin)': '-0.360', 'Mitotic cells (Skin)': '0.009', 'Parietal cells': '-0.352', 'Chief cells': '-0.303', 'Gastric mucous cells': '-0.072', 'Gastric enteroendocrine cells': '-0.148', 'Mitotic cells (Stomach)': '0.111', 'Parafollicular cells': '0.005', 'Thyroid glandular cells': '-0.055', 'Mitotic cells (Thyroid)': '0.346', 'Adrenal cortex cells': '0.171', 'Adrenal medulla cells': '-0.001', 'Mitotic cells (Adrenal gland)': '-0.127', 'Minor salivary glandular cells': '0.610', 'Minor salivary gland ductal cells': '0.258', 'Minor salivary gland basal cells': '0.129', 'Mitotic cells (Minor salivary gland)': '0.169', 'Adipocytes (Minor salivary gland)': '0.167', 'Somatotropes': '-0.211', 'Lactotropes': '-0.389', 'Gonadotropes': '0.036', 'Corticotropes': '-0.232', 'Thyrotropes': '-0.083', 'Undifferentiated cells (Pituitary gland)': '0.183', 'Mitotic cells (Spleen)': '-0.149', 'Platelets': '-0.130', 'Erythrocytes': '-0.171', 'Hematopoietic stem cells': '-0.172', 'B-cells (Spleen)': '0.435', 'NK-cells (Spleen)': '0.215', 'Amygdala excitatory': '0.7', 'Cerebellar inhibitory': '2.7', 'Cge interneuron': '0.4', 'Deep-layer corticothalamic and 6b': '0.4', 'Deep-layer intratelencephalic': '0.5', 'Deep-layer near-projecting': '0.1', 'Eccentric medium spiny neuron': '0.5', 'Hippocampal ca1-3': '0.5', 'Hippocampal ca4': '1.3', 'Hippocampal dentate gyrus': '0.5', 'Lamp5-lhx6 and chandelier': '0.9', 'Lower rhombic lip': '1.3', 'Mammillary body': '0.2', 'Medium spiny neuron': '0.4', 'Mge interneuron': '0.1', 'Midbrain-derived inhibitory': '0.0', 'Miscellaneous': '0.2', 'Splatter': '1.2', 'Thalamic excitatory': '2.3', 'Upper rhombic lip': '0.1', 'Upper-layer intratelencephalic': '0.6', 'Astrocyte': '3.0', 'Bergmann glia': '2.5', 'Central nervous system macrophage': '24.4', 'Choroid plexus epithelial cell': '0.7', 'Committed oligodendrocyte precursor': '1.6', 'Ependymal cell': '2.1', 'Oligodendrocyte': '0.7', 'Oligodendrocyte precursor cell': '2.0', 'Endothelial cell': '51.5', 'Pericyte': '15.8', 'Vascular associated smooth muscle cell': '12.1', 'Fibroblast': '17.8', 'Leukocyte': '94.2', 'Basophil': '92.3', 'Eosinophil': '5.6', 'Neutrophil': '3039.7', 'Classical monocyte': '535.9', 'Non-classical monocyte': '75.6', 'Intermediate monocyte': '1330.1', 'T-reg': '572.8', 'GdT-cell': '11.5', 'MAIT T-cell': '1817.4', 'Memory CD4 T-cell': '11.1', 'Naive CD4 T-cell': '1624.2', 'Memory CD8 T-cell': '10.9', 'Naive CD8 T-cell': '1289.0', 'Memory B-cell': '4.6', 'Naive B-cell': '193.4', 'Plasmacytoid DC': '146.7', 'Myeloid DC': '771.0', 'NK-cell': '630.7', 'Total PBMC': '438.1', 'Vd2 gdTCR': '1321.8', 'Memory CD4 T-cell Th1\\/Th17': '4758.2', 'Memory CD4 T-cell Th17': '2777.6', 'Memory CD4 T-cell Th2': '2696.4', 'Non-Vd2 gdTCR': '697.3', 'Memory CD4 T-cell Th1': '3101.6', 'Memory CD4 T-cell TFH': '1767.2', 'Terminal effector memory CD4 T-cell': '586.0', 'Central memory CD8 T-cell': '1346.2', 'Effector memory CD8 T-cell': '1030.8', 'Terminal effector memory CD8 T-cell': '643.9', 'Non-switched memory B-cell': '183.3', 'Plasmablast': '108.3', 'Switched memory B-cell': '133.9', 'Exhausted memory B-cell': '184.7', 'Progenitor cell': '61.7', 'Memory T-reg': '1316.7', 'Naive CD4 T-cell activated': '1454.6', 'Naive CD8 T-cell activated': '1341.5', 'Naive T-reg': '813.0'} | 2EQE, 2EQF, 2EQG, 2VFJ, 3DKB, 3OJ3, 3OJ4, 3VUW, 3VUX, 3VUY, 3ZJD, 3ZJE, 3ZJF, 3ZJG, 5LRX, 5V3B, 5V3P | {'Adipose Tissue': 71.89422425249168, 'Adrenal Gland': 18.808178294573644, 'Bladder': 27.82095238095238, 'Blood': 90.27551883745964, 'Blood Vessel': 22.304372284644195, 'Brain': 2.4634945495836487, 'Breast': 38.57104575163399, 'Cervix Uteri': 22.62152631578947, 'Colon': 29.911654685494224, 'Esophagus': 23.34145743944637, 'Fallopian Tube': 47.24111111111111, 'Heart': 12.724618118466898, 'Kidney': 16.023370786516853, 'Liver': 11.73166814159292, 'Lung': 103.90608996539792, 'Muscle': 5.374799252801993, 'Nerve': 35.55016155088853, 'Ovary': 131.08455555555557, 'Pancreas': 9.580134146341464, 'Pituitary': 13.757773851590104, 'Prostate': 30.354032653061225, 'Salivary Gland': 23.303753086419754, 'Skin': 55.29272028745163, 'Small Intestine': 50.19026737967914, 'Spleen': 57.31813278008299, 'Stomach': 21.495189415041786, 'Testis': 14.136614958448757, 'Thyroid': 23.792597243491574, 'Uterus': 30.784436619718313, 'Vagina': 27.45127564102564} | RNF41 | MGYDVTRFQGDVDEDLICPICSGVLEEPVQAPHCEHAFCNACITQWFSQQQTCPVDRSVVTVAHLRPVPRIMRNMLSKLQIACDNAVFGCSAVVRLDNLMSHLSDCEHNPKRPVTCEQGCGLEMPKDELPNHNCIKHLRSVVQQQQTRIAELEKTSAEHKHQLAEQKRDIQLLKAYMRAIRSVNPNLQNLEETIEYNEILEWVNSLQPARVTRWGGMISTPDAVLQAVIKRSLVESGCPASIVNELIENAHERSWPQGLATLETRQMNRRYYENYVAKRIPGKQAVVVMACENQHMGDDMVQEPGLVMIFAHGVEEI | Homo sapiens | null | Low tissue specificity | {'Ciliated cells': '14.6', 'Basal respiratory cells': '12.6', 'Club cells': '15.6', 'Ionocytes': '10.3', 'Mucus glandular cells': '12.9', 'Serous glandular cells': '8.7', 'Gastric mucus-secreting cells': '9.4', 'Proximal enterocytes': '11.7', 'Paneth cells': '17.7', 'Distal enterocytes': '11.7', 'Intestinal goblet cells': '9.9', 'Exocrine glandular cells': '-0.742', 'Basal prostatic cells': '21.1', 'Prostatic glandular cells': '36.5', 'Breast glandular cells': '-0.132', 'Breast myoepithelial cells': '-0.183', 'Glandular and luminal cells': '14.8', 'Secretory cells': '20.6', 'Basal keratinocytes': '17.8', 'Suprabasal keratinocytes': '18.2', 'Basal squamous epithelial cells': '16.0', 'Squamous epithelial cells': '13.4', 'Alveolar cells type 1': '0.173', 'Alveolar cells type 2': '0.099', 'Salivary duct cells': '15.5', 'Ductal cells': '0.668', 'Hepatocytes': '0.309', 'Cholangiocytes': '24.8', 'Proximal tubular cells': '0.205', 'Distal tubular cells': '12.3', 'Collecting duct cells': '15.6', 'Mesothelial cells': '0.188', 'Sertoli cells': '-0.257', 'Granulosa cells': '15.4', 'Enteroendocrine cells': '21.2', 'Pancreatic endocrine cells': '17.0', 'Leydig cells': '-0.237', 'Excitatory neurons': '14.5', 'Inhibitory neurons': '15.0', 'Cone photoreceptor cells': '27.2', 'Rod photoreceptor cells': '16.2', 'Bipolar cells': '27.2', 'Horizontal cells': '16.4', 'Astrocytes': '10.5', 'Oligodendrocyte precursor cells': '13.7', 'Oligodendrocytes': '11.4', 'Microglial cells': '8.9', 'Muller glia cells': '24.1', 'Schwann cells': '0.094', 'Spermatogonia': '0.009', 'Spermatocytes': '0.185', 'Early spermatids': '0.461', 'Late spermatids': '0.344', 'Oocytes': '8.1', 'Cytotrophoblasts': '15.7', 'Syncytiotrophoblasts': '16.8', 'Extravillous trophoblasts': '18.7', 'Endothelial cells': '19.0', 'Lymphatic endothelial cells': '19.2', 'Cardiomyocytes': '0.629', 'Skeletal myocytes': '-0.061', 'Smooth muscle cells': '23.9', 'Adipocytes': '18.9', 'Melanocytes': '0.058', 'Fibroblasts': '18.5', 'Peritubular cells': '-0.112', 'Endometrial stromal cells': '13.9', 'Ovarian stromal cells': '16.0', 'Undifferentiated cells': '15.9', 'T-cells': '17.9', 'B-cells': '41.7', 'Plasma cells': '13.8', 'Nk-cells': '18.2', 'Granulocytes': '16.2', 'Monocytes': '33.0', 'Macrophages': '25.1', 'Hofbauer cells': '21.6', 'Kupffer cells': '25.2', 'Dendritic cells': '24.1', 'Langerhans cells': '0.179', 'Erythroid cells': '-0.009', 'Adipocytes (Subcutaneous)': '0.529', 'Adipocytes (Visceral)': '0.412', 'Breast glandular cells (progenitors)': '-0.102', 'Adipocytes (Breast)': '0.500', 'Colon enterocytes': '-0.148', 'Colon enteroendocrine cells': '0.209', 'Enteric glia cells': '-0.035', 'Mitotic cells (Colon)': '-0.183', 'Mitotic cells (Heart)': '0.469', 'Podocytes': '-0.011', 'Ascending Loop of Henle cells': '0.408', 'Intercalated cells': '0.001', 'Cholangiocyte': '0.315', 'NK-cells (Liver)': '-0.302', 'Respiratory ciliated cells': '-0.086', 'Mitotic cells (Lung)': '-0.007', 'NK-cells (Lung)': '-0.080', 'B-cells (Lung)': '-0.195', 'Alpha cells': '0.421', 'Beta cells': '0.238', 'Prostate glandular cells': '0.530', 'Prostate basal glandular cells': '0.075', 'Urothelial cells': '-0.162', 'Keratinocyte (other)': '-0.027', 'Keratinocyte (granular)': '-0.060', 'Hair cortex cells': '0.129', 'Inner root sheath cells': '0.160', 'Outer root sheath cells': '0.220', 'Sebaceous gland cells': '0.212', 'Eccrine sweat gland cells': '0.059', 'Adipocytes (Skin)': '0.176', 'Mitotic cells (Skin)': '0.205', 'Parietal cells': '-0.716', 'Chief cells': '-0.576', 'Gastric mucous cells': '-0.481', 'Gastric enteroendocrine cells': '-0.456', 'Mitotic cells (Stomach)': '-0.040', 'Parafollicular cells': '0.087', 'Thyroid glandular cells': '0.441', 'Mitotic cells (Thyroid)': '-0.103', 'Adrenal cortex cells': '0.402', 'Adrenal medulla cells': '-0.037', 'Mitotic cells (Adrenal gland)': '0.184', 'Minor salivary glandular cells': '0.599', 'Minor salivary gland ductal cells': '0.113', 'Minor salivary gland basal cells': '0.255', 'Mitotic cells (Minor salivary gland)': '0.261', 'Adipocytes (Minor salivary gland)': '0.251', 'Somatotropes': '-0.020', 'Lactotropes': '0.135', 'Gonadotropes': '-0.156', 'Corticotropes': '0.081', 'Thyrotropes': '0.211', 'Undifferentiated cells (Pituitary gland)': '0.081', 'Mitotic cells (Spleen)': '-0.246', 'Platelets': '-0.144', 'Erythrocytes': '-0.115', 'Hematopoietic stem cells': '-0.258', 'B-cells (Spleen)': '0.520', 'NK-cells (Spleen)': '0.303', 'Amygdala excitatory': '20.7', 'Cerebellar inhibitory': '17.3', 'Cge interneuron': '28.1', 'Deep-layer corticothalamic and 6b': '21.1', 'Deep-layer 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P21580 | Q9NR96 | 30277474 | UbiBrowser | TNFAIP3 | MAEQVLPQALYLSNMRKAVKIRERTPEDIFKPTNGIIHHFKTMHRYTLEMFRTCQFCPQFREIIHKALIDRNIQATLESQKKLNWCREVRKLVALKTNGDGNCLMHATSQYMWGVQDTDLVLRKALFSTLKETDTRNFKFRWQLESLKSQEFVETGLCYDTRNWNDEWDNLIKMASTDTPMARSGLQYNSLEEIHIFVLCNILRRPIIVISDKMLRSLESGSNFAPLKVGGIYLPLHWPAQECYRYPIVLGYDSHHFVPLVTLKDSGPEIRAVPLVNRDRGRFEDLKVHFLTDPENEMKEKLLKEYLMVIEIPVQGWDHGTTHLINAAKLDEANLPKEINLVDDYFELVQHEYKKWQENSEQGRREGHAQNPMEPSVPQLSLMDVKCETPNCPFFMSVNTQPLCHECSERRQKNQNKLPKLNSKPGPEGLPGMALGASRGEAYEPLAWNPEESTGGPHSAPPTAPSPFLFSETTAMKCRSPGCPFTLNVQHNGFCERCHNARQLHASHAPDHTRHLDPGKCQACLQDVTRTFNGICSTCFKRTTAEASSSLSTSLPPSCHQRSKSDPSRLVRSPSPHSCHRAGNDAPAGCLSQAARTPGDRTGTSKCRKAGCVYFGTPENKGFCTLCFIEYRENKHFAAASGKVSPTASRFQNTIPCLGRECGTLGSTMFEGYCQKCFIEAQNQRFHEAKRTEEQLRSSQRRDVPRTTQSTSRPKCARASCKNILACRSEELCMECQHPNQRMGPGAHRGEPAPEDPPKQRCRAPACDHFGNAKCNGYCNECFQFKQMYG | Homo sapiens | Cytoplasm, Nucleus, Lysosome, Cytoplasm | Tissue enhanced (bone marrow, urinary bladder) | {'Ciliated cells': '222.0', 'Basal respiratory cells': '102.4', 'Club cells': '102.0', 'Ionocytes': '151.3', 'Mucus glandular cells': '266.5', 'Serous glandular cells': '115.3', 'Gastric mucus-secreting cells': '78.4', 'Proximal enterocytes': '42.9', 'Paneth cells': '17.5', 'Distal enterocytes': '30.6', 'Intestinal goblet cells': '32.1', 'Exocrine glandular cells': '-0.645', 'Basal prostatic cells': '87.8', 'Prostatic glandular cells': '11.6', 'Breast glandular cells': '0.196', 'Breast myoepithelial cells': '0.372', 'Glandular and luminal cells': '1464.3', 'Secretory cells': '239.6', 'Basal keratinocytes': '563.3', 'Suprabasal keratinocytes': '566.8', 'Basal squamous epithelial cells': '378.1', 'Squamous epithelial cells': '345.1', 'Alveolar cells type 1': '-0.009', 'Alveolar cells type 2': '-0.143', 'Salivary duct cells': '291.9', 'Ductal cells': '0.789', 'Hepatocytes': '0.134', 'Cholangiocytes': '21.0', 'Proximal tubular cells': '0.197', 'Distal tubular cells': '3.1', 'Collecting duct cells': '1.9', 'Mesothelial cells': '0.018', 'Sertoli cells': '0.075', 'Granulosa cells': '40.0', 'Enteroendocrine cells': '18.1', 'Pancreatic endocrine cells': '8.5', 'Leydig cells': '0.370', 'Excitatory neurons': '0.1', 'Inhibitory neurons': '0.3', 'Cone photoreceptor cells': '27.2', 'Rod photoreceptor cells': '15.7', 'Bipolar cells': '0.7', 'Horizontal cells': '1.9', 'Astrocytes': '1.9', 'Oligodendrocyte precursor cells': '1.9', 'Oligodendrocytes': '0.3', 'Microglial cells': '8.1', 'Muller glia cells': '5.5', 'Schwann cells': '0.011', 'Spermatogonia': '0.126', 'Spermatocytes': '-0.024', 'Early spermatids': '-0.035', 'Late spermatids': '-0.353', 'Oocytes': '5.1', 'Cytotrophoblasts': '8.5', 'Syncytiotrophoblasts': '19.6', 'Extravillous trophoblasts': '115.1', 'Endothelial cells': '144.9', 'Lymphatic endothelial cells': '37.6', 'Cardiomyocytes': '0.076', 'Skeletal myocytes': '0.359', 'Smooth muscle cells': '98.4', 'Adipocytes': '63.2', 'Melanocytes': '0.090', 'Fibroblasts': '83.8', 'Peritubular cells': '0.371', 'Endometrial stromal cells': '359.1', 'Ovarian stromal cells': '34.9', 'Undifferentiated cells': '12.6', 'T-cells': '778.2', 'B-cells': '95.4', 'Plasma cells': '280.9', 'Nk-cells': '411.5', 'Granulocytes': '1749.7', 'Monocytes': '1731.0', 'Macrophages': '777.5', 'Hofbauer cells': '176.5', 'Kupffer cells': '128.4', 'Dendritic cells': '129.5', 'Langerhans cells': '0.173', 'Erythroid cells': '0.154', 'Adipocytes (Subcutaneous)': '-0.425', 'Adipocytes (Visceral)': '-0.220', 'Breast glandular cells (progenitors)': '0.080', 'Adipocytes (Breast)': '-0.482', 'Colon enterocytes': '0.003', 'Colon enteroendocrine cells': '0.117', 'Enteric glia cells': '-0.193', 'Mitotic cells (Colon)': '0.097', 'Mitotic cells (Heart)': '0.354', 'Podocytes': '0.203', 'Ascending Loop of Henle cells': '0.015', 'Intercalated cells': '0.035', 'Cholangiocyte': '0.460', 'NK-cells (Liver)': '-0.192', 'Respiratory ciliated cells': '0.038', 'Mitotic cells (Lung)': '-0.111', 'NK-cells (Lung)': '0.178', 'B-cells (Lung)': '0.275', 'Alpha cells': '0.355', 'Beta cells': '0.236', 'Prostate glandular cells': '-0.177', 'Prostate basal glandular cells': '0.085', 'Urothelial cells': '0.154', 'Keratinocyte (other)': '0.355', 'Keratinocyte (granular)': '0.073', 'Hair cortex cells': '-0.229', 'Inner root sheath cells': '-0.173', 'Outer root sheath cells': '-0.203', 'Sebaceous gland cells': '-0.246', 'Eccrine sweat gland cells': '-0.219', 'Adipocytes (Skin)': '-0.360', 'Mitotic cells (Skin)': '0.009', 'Parietal cells': '-0.352', 'Chief cells': '-0.303', 'Gastric mucous cells': '-0.072', 'Gastric enteroendocrine cells': '-0.148', 'Mitotic cells (Stomach)': '0.111', 'Parafollicular cells': '0.005', 'Thyroid glandular cells': '-0.055', 'Mitotic cells (Thyroid)': '0.346', 'Adrenal cortex cells': '0.171', 'Adrenal medulla cells': '-0.001', 'Mitotic cells (Adrenal gland)': '-0.127', 'Minor salivary glandular cells': '0.610', 'Minor salivary gland ductal cells': '0.258', 'Minor salivary gland basal cells': '0.129', 'Mitotic cells (Minor salivary gland)': '0.169', 'Adipocytes (Minor salivary gland)': '0.167', 'Somatotropes': '-0.211', 'Lactotropes': '-0.389', 'Gonadotropes': '0.036', 'Corticotropes': '-0.232', 'Thyrotropes': '-0.083', 'Undifferentiated cells (Pituitary gland)': '0.183', 'Mitotic cells (Spleen)': '-0.149', 'Platelets': '-0.130', 'Erythrocytes': '-0.171', 'Hematopoietic stem cells': '-0.172', 'B-cells (Spleen)': '0.435', 'NK-cells (Spleen)': '0.215', 'Amygdala excitatory': '0.7', 'Cerebellar inhibitory': '2.7', 'Cge interneuron': '0.4', 'Deep-layer corticothalamic and 6b': '0.4', 'Deep-layer intratelencephalic': '0.5', 'Deep-layer near-projecting': '0.1', 'Eccentric medium spiny neuron': '0.5', 'Hippocampal ca1-3': '0.5', 'Hippocampal ca4': '1.3', 'Hippocampal dentate gyrus': '0.5', 'Lamp5-lhx6 and chandelier': '0.9', 'Lower rhombic lip': '1.3', 'Mammillary body': '0.2', 'Medium spiny neuron': '0.4', 'Mge interneuron': '0.1', 'Midbrain-derived inhibitory': '0.0', 'Miscellaneous': '0.2', 'Splatter': '1.2', 'Thalamic excitatory': '2.3', 'Upper rhombic lip': '0.1', 'Upper-layer intratelencephalic': '0.6', 'Astrocyte': '3.0', 'Bergmann glia': '2.5', 'Central nervous system macrophage': '24.4', 'Choroid plexus epithelial cell': '0.7', 'Committed oligodendrocyte precursor': '1.6', 'Ependymal cell': '2.1', 'Oligodendrocyte': '0.7', 'Oligodendrocyte precursor cell': '2.0', 'Endothelial cell': '51.5', 'Pericyte': '15.8', 'Vascular associated smooth muscle cell': '12.1', 'Fibroblast': '17.8', 'Leukocyte': '94.2', 'Basophil': '92.3', 'Eosinophil': '5.6', 'Neutrophil': '3039.7', 'Classical monocyte': '535.9', 'Non-classical monocyte': '75.6', 'Intermediate monocyte': '1330.1', 'T-reg': '572.8', 'GdT-cell': '11.5', 'MAIT T-cell': '1817.4', 'Memory CD4 T-cell': '11.1', 'Naive CD4 T-cell': '1624.2', 'Memory CD8 T-cell': '10.9', 'Naive CD8 T-cell': '1289.0', 'Memory B-cell': '4.6', 'Naive B-cell': '193.4', 'Plasmacytoid DC': '146.7', 'Myeloid DC': '771.0', 'NK-cell': '630.7', 'Total PBMC': '438.1', 'Vd2 gdTCR': '1321.8', 'Memory CD4 T-cell Th1\\/Th17': '4758.2', 'Memory CD4 T-cell Th17': '2777.6', 'Memory CD4 T-cell Th2': '2696.4', 'Non-Vd2 gdTCR': '697.3', 'Memory CD4 T-cell Th1': '3101.6', 'Memory CD4 T-cell TFH': '1767.2', 'Terminal effector memory CD4 T-cell': '586.0', 'Central memory CD8 T-cell': '1346.2', 'Effector memory CD8 T-cell': '1030.8', 'Terminal effector memory CD8 T-cell': '643.9', 'Non-switched memory B-cell': '183.3', 'Plasmablast': '108.3', 'Switched memory B-cell': '133.9', 'Exhausted memory B-cell': '184.7', 'Progenitor cell': '61.7', 'Memory T-reg': '1316.7', 'Naive CD4 T-cell activated': '1454.6', 'Naive CD8 T-cell activated': '1341.5', 'Naive T-reg': '813.0'} | 2EQE, 2EQF, 2EQG, 2VFJ, 3DKB, 3OJ3, 3OJ4, 3VUW, 3VUX, 3VUY, 3ZJD, 3ZJE, 3ZJF, 3ZJG, 5LRX, 5V3B, 5V3P | {'Adipose Tissue': 71.89422425249168, 'Adrenal Gland': 18.808178294573644, 'Bladder': 27.82095238095238, 'Blood': 90.27551883745964, 'Blood Vessel': 22.304372284644195, 'Brain': 2.4634945495836487, 'Breast': 38.57104575163399, 'Cervix Uteri': 22.62152631578947, 'Colon': 29.911654685494224, 'Esophagus': 23.34145743944637, 'Fallopian Tube': 47.24111111111111, 'Heart': 12.724618118466898, 'Kidney': 16.023370786516853, 'Liver': 11.73166814159292, 'Lung': 103.90608996539792, 'Muscle': 5.374799252801993, 'Nerve': 35.55016155088853, 'Ovary': 131.08455555555557, 'Pancreas': 9.580134146341464, 'Pituitary': 13.757773851590104, 'Prostate': 30.354032653061225, 'Salivary Gland': 23.303753086419754, 'Skin': 55.29272028745163, 'Small Intestine': 50.19026737967914, 'Spleen': 57.31813278008299, 'Stomach': 21.495189415041786, 'Testis': 14.136614958448757, 'Thyroid': 23.792597243491574, 'Uterus': 30.784436619718313, 'Vagina': 27.45127564102564} | TLR9 | MGFCRSALHPLSLLVQAIMLAMTLALGTLPAFLPCELQPHGLVNCNWLFLKSVPHFSMAAPRGNVTSLSLSSNRIHHLHDSDFAHLPSLRHLNLKWNCPPVGLSPMHFPCHMTIEPSTFLAVPTLEELNLSYNNIMTVPALPKSLISLSLSHTNILMLDSASLAGLHALRFLFMDGNCYYKNPCRQALEVAPGALLGLGNLTHLSLKYNNLTVVPRNLPSSLEYLLLSYNRIVKLAPEDLANLTALRVLDVGGNCRRCDHAPNPCMECPRHFPQLHPDTFSHLSRLEGLVLKDSSLSWLNASWFRGLGNLRVLDLSENFLYKCITKTKAFQGLTQLRKLNLSFNYQKRVSFAHLSLAPSFGSLVALKELDMHGIFFRSLDETTLRPLARLPMLQTLRLQMNFINQAQLGIFRAFPGLRYVDLSDNRISGASELTATMGEADGGEKVWLQPGDLAPAPVDTPSSEDFRPNCSTLNFTLDLSRNNLVTVQPEMFAQLSHLQCLRLSHNCISQAVNGSQFLPLTGLQVLDLSHNKLDLYHEHSFTELPRLEALDLSYNSQPFGMQGVGHNFSFVAHLRTLRHLSLAHNNIHSQVSQQLCSTSLRALDFSGNALGHMWAEGDLYLHFFQGLSGLIWLDLSQNRLHTLLPQTLRNLPKSLQVLRLRDNYLAFFKWWSLHFLPKLEVLDLAGNQLKALTNGSLPAGTRLRRLDVSCNSISFVAPGFFSKAKELRELNLSANALKTVDHSWFGPLASALQILDVSANPLHCACGAAFMDFLLEVQAAVPGLPSRVKCGSPGQLQGLSIFAQDLRLCLDEALSWDCFALSLLAVALGLGVPMLHHLCGWDLWYCFHLCLAWLPWRGRQSGRDEDALPYDAFVVFDKTQSAVADWVYNELRGQLEECRGRWALRLCLEERDWLPGKTLFENLWASVYGSRKTLFVLAHTDRVSGLLRASFLLAQQRLLEDRKDVVVLVILSPDGRRSRYVRLRQRLCRQSVLLWPHQPSGQRSFWAQLGMALTRDNHHFYNRNFCQGPTAE | Homo sapiens | Endoplasmic reticulum membrane, Early endosome membrane, Lysosome, Cytoplasmic vesicle, phagosome, Golgi apparatus membrane | Tissue enhanced (lymphoid) | {'Ciliated cells': '0.0', 'Basal respiratory cells': '0.0', 'Club cells': '0.0', 'Ionocytes': '0.0', 'Mucus glandular cells': '0.0', 'Serous glandular cells': '0.0', 'Gastric mucus-secreting cells': '0.0', 'Proximal enterocytes': '0.0', 'Paneth cells': '0.0', 'Distal enterocytes': '0.0', 'Intestinal goblet cells': '0.0', 'Exocrine glandular cells': '-0.269', 'Basal prostatic cells': '0.0', 'Prostatic glandular cells': '0.0', 'Breast glandular cells': '0.372', 'Breast myoepithelial cells': '0.347', 'Glandular and luminal cells': '0.0', 'Secretory cells': '0.0', 'Basal keratinocytes': '0.0', 'Suprabasal keratinocytes': '0.0', 'Basal squamous epithelial cells': '0.0', 'Squamous epithelial cells': '0.0', 'Alveolar cells type 1': '0.004', 'Alveolar cells type 2': '-0.335', 'Salivary duct cells': '0.0', 'Ductal cells': '0.397', 'Hepatocytes': '0.084', 'Cholangiocytes': '0.0', 'Proximal tubular cells': '0.067', 'Distal tubular cells': '0.0', 'Collecting duct cells': '0.0', 'Mesothelial cells': '0.389', 'Sertoli cells': '0.518', 'Granulosa cells': '0.0', 'Enteroendocrine cells': '0.0', 'Pancreatic endocrine cells': '0.0', 'Leydig cells': '0.328', 'Excitatory neurons': '0.3', 'Inhibitory neurons': '0.3', 'Cone photoreceptor cells': '0.0', 'Rod photoreceptor cells': '0.0', 'Bipolar cells': '0.0', 'Horizontal cells': '0.0', 'Astrocytes': '0.0', 'Oligodendrocyte precursor cells': '0.0', 'Oligodendrocytes': '0.2', 'Microglial cells': '0.9', 'Muller glia cells': '0.0', 'Schwann cells': '0.125', 'Spermatogonia': '0.125', 'Spermatocytes': '-0.234', 'Early spermatids': '-0.564', 'Late spermatids': '-0.460', 'Oocytes': '0.0', 'Cytotrophoblasts': '0.0', 'Syncytiotrophoblasts': '0.0', 'Extravillous trophoblasts': '0.0', 'Endothelial cells': '0.0', 'Lymphatic endothelial cells': '0.0', 'Cardiomyocytes': '0.203', 'Skeletal myocytes': '0.118', 'Smooth muscle cells': '0.0', 'Adipocytes': '0.0', 'Melanocytes': '-0.294', 'Fibroblasts': '0.0', 'Peritubular cells': '0.368', 'Endometrial stromal cells': '0.0', 'Ovarian stromal cells': '0.0', 'Undifferentiated cells': '0.1', 'T-cells': '0.0', 'B-cells': '3.4', 'Plasma cells': '3.2', 'Nk-cells': '0.0', 'Granulocytes': '0.0', 'Monocytes': '0.0', 'Macrophages': '0.0', 'Hofbauer cells': '0.0', 'Kupffer cells': '0.0', 'Dendritic cells': '0.0', 'Langerhans cells': '-0.122', 'Erythroid cells': '0.033', 'Adipocytes (Subcutaneous)': '-0.075', 'Adipocytes (Visceral)': '-0.233', 'Breast glandular cells (progenitors)': '0.327', 'Adipocytes (Breast)': '-0.371', 'Colon enterocytes': '-0.152', 'Colon enteroendocrine cells': '0.141', 'Enteric glia cells': '0.568', 'Mitotic cells (Colon)': '-0.197', 'Mitotic cells (Heart)': '0.067', 'Podocytes': '-0.014', 'Ascending Loop of Henle cells': '0.256', 'Intercalated cells': '0.011', 'Cholangiocyte': '0.206', 'NK-cells (Liver)': '-0.004', 'Respiratory ciliated cells': '0.004', 'Mitotic cells (Lung)': '-0.169', 'NK-cells (Lung)': '0.184', 'B-cells (Lung)': '0.188', 'Alpha cells': '0.277', 'Beta cells': '0.157', 'Prostate glandular cells': '-0.265', 'Prostate basal glandular cells': '-0.054', 'Urothelial cells': '0.151', 'Keratinocyte (other)': '-0.279', 'Keratinocyte (granular)': '-0.132', 'Hair cortex cells': '0.020', 'Inner root sheath cells': '0.046', 'Outer root sheath cells': '0.118', 'Sebaceous gland cells': '-0.031', 'Eccrine sweat gland cells': '0.271', 'Adipocytes (Skin)': '0.245', 'Mitotic cells (Skin)': '-0.157', 'Parietal cells': '-0.559', 'Chief cells': '-0.512', 'Gastric mucous cells': '-0.309', 'Gastric enteroendocrine cells': '-0.338', 'Mitotic cells (Stomach)': '-0.086', 'Parafollicular cells': '0.016', 'Thyroid glandular cells': '-0.049', 'Mitotic cells (Thyroid)': '0.164', 'Adrenal cortex cells': '0.209', 'Adrenal medulla cells': '-0.002', 'Mitotic cells (Adrenal gland)': '-0.056', 'Minor salivary glandular cells': '0.357', 'Minor salivary gland ductal cells': '0.193', 'Minor salivary gland basal cells': '-0.194', 'Mitotic cells (Minor salivary gland)': '-0.062', 'Adipocytes (Minor salivary gland)': '0.154', 'Somatotropes': '-0.173', 'Lactotropes': '-0.241', 'Gonadotropes': '-0.071', 'Corticotropes': '-0.216', 'Thyrotropes': '-0.096', 'Undifferentiated cells (Pituitary gland)': '0.391', 'Mitotic cells (Spleen)': '0.059', 'Platelets': '0.144', 'Erythrocytes': '-0.117', 'Hematopoietic stem cells': '0.039', 'B-cells (Spleen)': '0.510', 'NK-cells (Spleen)': '-0.017', 'Amygdala excitatory': '0.3', 'Cerebellar inhibitory': '0.1', 'Cge interneuron': '0.4', 'Deep-layer corticothalamic and 6b': '0.1', 'Deep-layer intratelencephalic': '0.2', 'Deep-layer near-projecting': '0.3', 'Eccentric medium spiny neuron': '0.4', 'Hippocampal ca1-3': '0.5', 'Hippocampal ca4': '0.1', 'Hippocampal dentate gyrus': '0.1', 'Lamp5-lhx6 and chandelier': '0.6', 'Lower rhombic lip': '0.1', 'Mammillary body': '0.2', 'Medium spiny neuron': '0.4', 'Mge interneuron': '0.3', 'Midbrain-derived inhibitory': '0.2', 'Miscellaneous': '0.2', 'Splatter': '0.3', 'Thalamic excitatory': '0.3', 'Upper rhombic lip': '0.9', 'Upper-layer intratelencephalic': '0.3', 'Astrocyte': '0.7', 'Bergmann glia': '0.4', 'Central nervous system macrophage': '0.9', 'Choroid plexus epithelial cell': '0.0', 'Committed oligodendrocyte precursor': '0.2', 'Ependymal cell': '0.1', 'Oligodendrocyte': '0.3', 'Oligodendrocyte precursor cell': '0.3', 'Endothelial cell': '0.1', 'Pericyte': '0.6', 'Vascular associated smooth muscle cell': '0.4', 'Fibroblast': '0.3', 'Leukocyte': '0.4', 'Basophil': '4.3', 'Eosinophil': '0.0', 'Neutrophil': '12.4', 'Classical monocyte': '0.2', 'Non-classical monocyte': '0.1', 'Intermediate monocyte': '0.7', 'T-reg': '0.6', 'GdT-cell': '0.2', 'MAIT T-cell': '1.9', 'Memory CD4 T-cell': '0.9', 'Naive CD4 T-cell': '0.3', 'Memory CD8 T-cell': '0.6', 'Naive CD8 T-cell': '0.4', 'Memory B-cell': '23.6', 'Naive B-cell': '0.1', 'Plasmacytoid DC': '456.0', 'Myeloid DC': '1.1', 'NK-cell': '0.1', 'Total PBMC': '5.5', 'Vd2 gdTCR': '0.6', 'Memory CD4 T-cell Th1\\/Th17': '0.2', 'Memory CD4 T-cell Th17': '0.2', 'Memory CD4 T-cell Th2': '0.3', 'Non-Vd2 gdTCR': '0.5', 'Memory CD4 T-cell Th1': '0.3', 'Memory CD4 T-cell TFH': '0.3', 'Terminal effector memory CD4 T-cell': '1.9', 'Central memory CD8 T-cell': '1.1', 'Effector memory CD8 T-cell': '0.1', 'Terminal effector memory CD8 T-cell': '0.1', 'Non-switched memory B-cell': '68.6', 'Plasmablast': '23.6', 'Switched memory B-cell': '45.3', 'Exhausted memory B-cell': '46.5', 'Progenitor cell': '3.4', 'Memory T-reg': '0.3', 'Naive CD4 T-cell activated': '0.1', 'Naive CD8 T-cell activated': '0.1', 'Naive T-reg': '0.3'} | 8AR3 | {'Adipose Tissue': 1.4036666528239203, 'Adrenal Gland': 0.5379480620155039, 'Bladder': 2.0188523809523806, 'Blood': 11.078379773950484, 'Blood Vessel': 2.045118501872659, 'Brain': 1.6826528425435276, 'Breast': 1.1921779956427014, 'Cervix Uteri': 3.774784210526316, 'Colon': 1.9339365853658537, 'Esophagus': 1.4013961660899654, 'Fallopian Tube': 2.7071555555555555, 'Heart': 0.46085, 'Kidney': 0.6571056179775281, 'Liver': 0.3677314159292035, 'Lung': 1.7192410034602077, 'Muscle': 1.6459444707347448, 'Nerve': 2.427732633279483, 'Ovary': 4.217165, 'Pancreas': 0.1862323780487804, 'Pituitary': 1.0853265017667846, 'Prostate': 2.0451526530612245, 'Salivary Gland': 1.022793209876543, 'Skin': 0.6458710497512438, 'Small Intestine': 6.100227272727273, 'Spleen': 8.518240663900416, 'Stomach': 0.8774933147632312, 'Testis': 1.5356736842105263, 'Thyroid': 1.930964318529862, 'Uterus': 3.011875352112676, 'Vagina': 2.4533397435897437} | [38.31, 42.03, 49.95, 61.2, 82.7, 89.84, 88.57, 90.92, 87.37, 88.64, 84.74, 88.68, 88.81, 90.09, 87.25, 88.0, 91.06, 89.29, 90.79, 94.26, 96.39, 96.34, 95.4, 97.09, 97.09, 97.34, 96.94, 98.01, 97.38, 96.68, 94.0, 92.19, 90.04, 89.07, 84.43, 89.02, 93.2, 92.45, 97.46, 98.35, 98.0, 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| null | null | IKBKG, ITCH, YWHAH, TRAF6, RIPK1, TRAF2, TNIP1, TAX1BP1, RNF11, YWHAZ | UBE2N, UBE2D3, RIPK1 | 11, 48, 63 | null | UBE2N, UBE2D3 | Homodimer | null | 74.507911 | 0.508165 | 87.039147 | 0.338808 | 486 |
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