title stringlengths 0 901 | abstract stringlengths 3 9.89k | PMID int64 22 25.3M | embedding listlengths 768 768 |
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Endocrinological changes in patients with sexual dysfunction under long-term neuroleptic treatment. | Endocrine changes induced by dopaminergic inhibition may play a part in the development of sexual dysfunction (reduced libido/potency) in schizophrenic patients on long-term neuroleptic treatment. Prolactin, testosterone, LH and FSH serum level determinations by radioimmunoassays were performed in 24 schizophrenic male... | 538,087 | [
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Comparison of temperature effect on the guanidine hydrochloride and urea denaturations of lysozyme. | Guanidine hydrochloride (GdnHCl) and urea denaturations of lysozyme have been observed at various temperatures by measuring changes in fluorescence. Both transitions appear to be two state, with GdnHCl almost twice as effecitve a denaturant as urea for this protein. By plotting the denaturant concentrations at midpoint... | 538,098 | [
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Plasma volume contraction: a significant factor in both pregnancy-associated hypertension (pre-eclampsia) and chronic hypertension in pregnancy. | The role of plasma volume in hypertension in pregnancy (pre-eclampsia) was investigated. Significant volume expansion from non-pregnant levels (16.5 +/- 1.60 ml/cm height) was present throughout pregnancy in 189 normal women, reaching 23.1 +/- 1.21 ml/cm at 33-36 weeks amenorrhoea. In another 40 initially normotensive ... | 538,221 | [
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[Freedom in disorders of the mind and spirit]. | The much used and popular word "freedom" is being examined as to its significance and in that context the peculiar expression "freedom of will" is also brought into the discussion. In the course of this clarification, philosophy, jurisprudence, poetic-literary and our everyday language all had to lend a hand. In its ap... | 538,273 | [
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A mathematical model for the 1973 cholera epidemic in the European Mediterranean region. | For the cholera epidemic that occurred in the European Mediterranean region in the summer of 1973, a simple deterministic mathematic model is proposed; it consists of a system of two ordinary differential equations which concern the evolution of the human infective population in a town community and of bacteria populat... | 538,301 | [
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[Who needs more psychosocial oriented rehabilitation -- women after breast cancer or women after genital cancer? -- A sociopsychological study of 308 women (author's transl)]. | A standardised questionnaire and personality test were used to study whether women after breast cancer treatment, or women treated for genital cancer need psychosocial counselling more frequently. The interview was given to 308 women during the author's tumor after-care consultations. 1. Repercussion on their marital l... | 538,330 | [
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[On the therapy and rebabilitation of juvenile drug addits in a special hospital (author's transl)]. | A successful therapy of drug-dependents can only be carried out in special facilities providing intensive inter-disciplinary care. In the Hochstadt district hospital (Bezirksklinik Hochstadt) treatment encompasses detoxication, weaning and after-care. The goal of the therapy is the permanent abstinence of the patient, ... | 538,332 | [
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Calcium hypersensitivity in airways smooth muscle. Isometric tension responses following anaphylaxis. | The isometric tension of anaphylactic guinea pig trachealis muscle preparation was examined at subphysiologic extracellular calcium concentrations, in vitro. Paired observations of control to passively sensitized (egg albumin antiserum) and antigen-challenged muscles (anaphylaxis) were made to exposure to trace Ca++ fo... | 538,335 | [
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Condylomatous changes in neoplastic bronchial epithelium. Report of a case. | The present communication is a report of a case where histological changes, identical to those described recently to be of condylomatous nature in the genital tract, were found in the bronchial epithelium adjacent to an invasive squamous cell carcinoma. The significance of this finding in the light of squamous cell car... | 538,337 | [
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[Lumbar phelbography without catheterization. Technic, indications and results in the diagnosis of intervertebral disk herniation]. | The authors present a new method of lumbar phlebology without catheterism by direct venous puncture of the femoral veins. An analysis of 300 contrast tests maked it possible to identify different types of pathological images characterized by disappearance and displacement of epidural veins corresponding as a rule to di... | 538,402 | [
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[Massive and sudden bone resorption in rapid destructive coxarthrosis. Radiologic and anatomic study]. | Twenty hips with rapid destructive coxarthrosis (early form, 3; delayed form, 17) showed, during their development, a massive and sudden bone resorption. Preexisting problems of the bone structure of the hips were dispersed and constantly changing; they were different from those of common arthrosis and primary necrosis... | 538,404 | [
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Acquired, transient factor X (Stuart factor) deficiency in patient with mycoplasma pneumonial infection. | A case of severe haemorrhagic diathesis due to acquired deficiency of factor X (both immunologically and in procoagulant activity) is presented. The clinical and serological features of this case indicated mycoplasma pneumonial infection. Factor X in the peripheral blood did not appear to be influenced by administratio... | 538,412 | [
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Immunoprofile studies in patients with pulmonary tuberculosis. IV. Tuberculin skin reaction and test of inhibition of blood leukcoyte migration. | Study of the relationship existing between in vivo and in vitro correlates of cell immunity has revealed that there is no marked correlation between the magnitude of skin induration of the tuberculin skin test and the degree of inhibition of migration of blood leukocytes stimulated by PPD in patients with newly detecte... | 538,419 | [
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Increased frequency of chromosome aberrations in workers exposed to styrene. | Chromosomal aberrations in lymphocytes from peripheral blood were significantly more frequent in six workers from a plant manufacturing polyester resin boats (average 10.8 per 100 cells) than in six age-and sex-matched referents (5.2 per 100 cells). The contamination of the workroom air with styrene, as measured on thr... | 538,423 | [
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Blood flow in the contralateral hand during vibration and hand grip contractions of lumberjacks. | Pulse wave changes were examined among 63 professional lumberjacks. The tests were carried out in connection with an annual health examination. A photoelectric plethysmographic method was used to measure pulse wave changes during contralateral muscle work and vibration exposure from a dynamic shaker with a strain-gauge... | 538,428 | [
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[Retinoid in the treatment of psoriatic arthropathy: a pilot study]. | Four patients with active seronegative psoriatic arthropathy were treated with retinoid (Ro 10-9359) in a daily dose of 30 mg for at least four months. Within the first 4--6 weeks of treatment all patients showed marked improvement of arthritis as measured by the number of swollen joints, the Ritchie joint index, morni... | 538,432 | [
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[Pharmacokinetics of a new cephalosporin, cefoperazone]. | Cefoperazone is a semi-synthetic cephalosporin for parenteral use with an extended antibacterial spectrum covering Pseudomonas aeruginosa, Enterobacter cloacae and Serratia marcescens. Its pharmacokinetic properties were studied in 8 healthy subjects after 2 intravenous infusions of 2 g of the drug at a 12-hour interva... | 538,442 | [
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The rate of urinary excretion of phosalone residues in occupationally exposed persons. | The absorption of malathion and phosalone was followed in occupationally exposed workers by determination of residues excreted in the urine. Because of the high concentrations found in the morning urine samples, the rates of excretion of phosalone metabolites in the urine of a volunteer experimentally exposed to phosal... | 538,451 | [
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Simultaneous determination of biliary cile acids in rat: electron impact and ammonia chemical ionization mass spectrometric analyses of bile acids. | Bile acids in the rat bile were fractionated into unconjugated, glycine- and taurine-conjugated fractions by employing piperidino-hydroxypropyl Sephadex LH-20 ion-exchange chromatography. Subsequently, these fractions were analyzed by gas-liquid chromatography (GLC) and GLC-mass spectrometry using a Silicone AN-600 col... | 538,777 | [
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Ponasterone A: a new ecdysteroid from the embryos and serum of brachyuran crustaceans. | The apolar ecdysteroid present in the developing embryo of the blue crab, Callinectes sapidus Rathbun, is tentatively identified as ponasterone A (2 beta, 14 alpha, 20,22-pentahydroxy-5, beta-cholest-7-en-6-one) on the basis of chromatographic, immunological, and mass spectral evidence. The apolar ecdysteroid present i... | 538,780 | [
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Prediction of the protein requirements of farm ruminants and implications of these predictions for diet formulation. | Methods of determining protein requirements are reviewed and recent proposals of the Agricultural Research Council working party on nutrient requirements of ruminants outlined. Needs of the rumen microorganisms for degradable nitrogen to achieve optimum rumen digestion of feed are predicted. The extent to which milk pr... | 538,878 | [
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Epidemiological investigations on viral hepatitis in preschool and school communities. Note III. Sources of infection for HBsAg carriers and former viral hepatitis patients. | HBsAg carriers and viral hepatitis B patients detected in preschool and school communities as well as members of their families were subjected to thorough epidemiological investigations. The source of infection was represented by the community in 33.3% of the preschool children and in 26.5% of the schoolchildren and by... | 538,882 | [
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Substructural studies on sporulation of Saccharomycopsis lipolytica. | During sporulation of diploids from crosses between different strains of the yeast Saccharomycopsis (Candida) lipolytica irregular numbers of ascospores per ascus have been observed. Using the serial section method it could be shown now by means of electron microscopy that in one-, two-, and three-spored asci unenclose... | 538,958 | [
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[On cyclic rejuvenation of life in change of generations (author's transl)]. | Various cellular processes are discussed which might be able to reduce in protozoa as well as in higher organisms the accumulation of "errors" in protein synthesis by the interplay of error accumulation and cell division frequency or by katabolic effects after a generative process of one kind or another. Some of these ... | 538,965 | [
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[The formation of lipofuscin (author's transl)]. | The article deals with the present knowledge of the lipofuscin-formation. Lipofuscin is regarded as a lysosomal residue body and as a product of peroxidation and polymerisation of unsaturated fatty acids. Starting from this aspects conditions are derived, which favour the lipofuscin-formation. These factors are divided... | 538,968 | [
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[Hepatologic dispensaire for blood donors]. | By means of hepatological examinations of 119 blood donors who became conspicuous by liver screenings in 57 cases we could prove an adipose degeneration without, in 16 cases a fatty degeneration of the liver without, in 9 cases an adipose degeneration with and in 15 cases a fatty degeneration of the liver with mesenchy... | 538,987 | [
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[Serology of toxoplasmosis in patients with lymphogranulomatosis]. | The technical progress in the development of the fiber coloscopy gives the possibility to inspect the whole large intestine including the terminal ileum. The essential contribution of the coloscopy consists in the early diagnosis of the carcinoma of the large intestine. The malignant change of the polyp may be proved o... | 539,006 | [
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Characterization of Eimeria species. I. Isolation and study of pathogenicity of a pure strain of Eimeria perforans (Leuckart, 1879; Sluiter and Swellengrebel, 1912). | Eimeria perforans was isolated in pure strain by utilizing specific biological characters and specific-pathogen free rabbits. The purity of this strain was demonstrated by measurements of oocysts, derived from a line, started by infection from a single oocyst. The parasite, when inoculated in large numbers, causes a mi... | 539,069 | [
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0.47596... |
[An overview of health education in Switzerland]. | The present research is an attempt to give an overall view of health education programmes in Switzerland. Three phases are planned: 1. Inventory of health education programmes, 2. evaluation of these programmes, 3. recommendations for the improvement of the present situation. The present paper gives the underlying conc... | 539,142 | [
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[Irtitation by smell in the neighborhood of a garbage burning plant]. | Dilution threshold values were measured using sensory methods for an evaluation of odorous emissions of an incineration plant. The dispersion of odours was estimated based on recording of the local wind. The level of public annoyance in the neighbouring residential areas will be assessed by special questionnaires. | 539,159 | [
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Leiomyomas of the larynx. | In a now 65 years old male patient a monochorditis of the left vocal cord was clinically observed over several years. Multiple exploratory excisions finally demonstrated a leiomyoma with atypically growing histological structures. The complaints of the patient permanently increased, and a hazel-nut-sized leiomyoma with... | 539,173 | [
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Renal vein thrombosis in the newborn. | Abdominal masses localized to the region of the kidney in the newborn require different diagnostic procedures. Taking advantage of cystourethrography, retrograde and intravenous pyelography and angiography, it should be possible to make the right diagnosis as in our two cases demonstrating renal vein thrombosis. | 539,334 | [
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Bilateral renal artery stenosis/occlusion and renovascular hypertension. Correlation of angiographic findings with blood pressure response after surgery. | In a previous study of unilateral renal artery stenosis the angiograms of patients with a favourable blood pressure response after surgery were found to be characterized by a reduction of renal arterial lumen greater than or equal to 90% and/or renal collateral circulation. Ancillary features were post-stenotic dilatat... | 539,339 | [
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Appendicectomy during pregnancy. | Twenty-four appendicectomies were performed during intra-uterine pregnancy at the Department of Surgery of the University Central Hospital, Turku, in the period 1963--77. Six out of 14 cases of appendicitis occurred in the third trimester. The incidence of appendicitis during pregnancy was 1 : 1 445. In 9 cases the app... | 539,341 | [
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Colonoscopic appendectomy. Report of two cases. | Colonoscopic appendectomy has been performed in two patients, who had had their appendices inverted into the caecum as an incidental procedure at earlier abdominal surgery. | 539,345 | [
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Neuropharmacological activity of newly-synthethized derivatives of 3,3-diethyl-2,4-pyridinedione. III. N-Acyl derivatives of 3,3-diethyl-2,4-pyridinedione. | Neuropharmacological screening of five newly-synthesized derivatives of 3,3-diethyl-2,4-pyridinedione was carried out on albino mice. It was found that the N-acyl derivatives have a central depressive effect which is different in character compared with the effect of diethylpyridinedione. The compounds possess no hypno... | 539,450 | [
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Tachycardia during egg-hypothermia in incubating ptarmigan (Lagopus lagopus). | Incubating birds regulate the egg temperature by varying their posture and the distance between eggs and brood patch. In the present study, we show that this homeostatic process is further assisted by varying the brood patch blood flow according to the temperature of the eggs. When female ptarmigan resume incubation of... | 539,457 | [
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Histological and histochemical studies on the innervation of the respiratory organs of Calotes versicolor Daud. (Agamidae, Lacertilia). | A study on the innervation of the respiratory organs of Calotes versicolor has been made using cholinesterase and silver reduction techniques. The tracheal and bronchial plexuses have been described. A number of nerve terminations along with synapses are reported. ChE activity has been observed on the periphery of the ... | 539,471 | [
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Auditory frequency generalization in normal and prefrontal dogs trained in varieties of active avoidance reflexes. | Twelve dogs were trained to avoid shock with response contingent termination of a 1000 Hz tonal CS on all trials, whereas 12 additional dogs received the same training except that on 50 percent trials there was a fixed CS duration and no shock. Initial acquisition revealed that CS prolongation resulted in longer respon... | 539,475 | [
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[Neuropediatric follow-up studies of preterm born babies with birth weight below 1600 g (author's transl)]. | Neuropediatric follow-up studies during 18 months of preterm born babies with birth weight below 1600 g show a normal development in 70%. Better perinatological and neuropediatric long-term care are taken as causes of the improved developmental prognosis of children at risk in recent years. | 539,497 | [
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[Effects of levamisole in the treatment of a group of patients with atopic asthma and depression cellular immunity]. | We investigated the possibility of decreased cellular immunity (C.I.) in a substantial group of atopic asthmatic patients with respiratory tract infections during autumn and winter. Two-hundred and ten atopic asthmatic patients were selected, and the following tests for cellular immunity were performed. Skin tests with... | 539,520 | [
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Total elemental content passive personal monitors. | The development of specific passive personal monitors for each volatile form of an element should ultimately lead to a common monitor which can detect any or all forms of that element. Such a device is presented here as a total elemental content passive personal monitor and depends upon diffusion to bring gaseous pollu... | 539,545 | [
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Testing a causal model of environmental influences on the early drug involvement of inner city junior high school youths. | The present study examines a causal model explaining inner city youths' drug involvement using environmental variables which previously have been investigated singly or in various combinations and shown to influence drug use: the availability of drugs in the neighborhood and at school, a view of the neighborhood as tou... | 539,574 | [
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The effect of BCNU and adriamycin on normal and G6PD deficient erythrocytes. | In cell free systems Adriamycin induces oxygen radicals. We have shown previously that Adriamycin generates peroxide in human erythrocytes. BCNU, by inhibiting glutathione reductase, interferes with the major erythrocyte pathway to degrade peroxide. In this investigation we looked at interactions of these drugs with no... | 539,595 | [
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[Total atrophy of the villi during primary agammaglobulinemia in adults. Therapeutic problems (author's transl)]. | A 21-year-old man presented with a 10-year history of a malabsorption syndrome of moderate severity, splenomegaly, and recurrent respiratory infections. Investigations revealed total atrophy of the villi and primary agammaglobulinemia. A gluten-free diet was ineffective. In spite of the absence of lambliasis, treatment... | 539,685 | [
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[Myocardiopathy from a new anthracyclic derivative (author's transl)]. | A 58-year-old man with subcutaneous metastases from a naevocarcinoma was prescribed 1 138 mg/m2 of a new anthracylic derivative, dietoxy-acetoxy-daunorubicine, at doses of 180 mg every three weeks. Irreversible cardiac failure occurred nine months after starting treatment, and was considered to be due to the toxic effe... | 539,690 | [
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... |
[Tinea capitis: 73 cases observed in Bordeaux (author's transl)]. | 73 cases of tinea capitis were observed in the "Hôpital des Enfants" in Bordeaux during these last five year. 71 children under 14 years of age and only 2 adults have seen. The dermatophytic spectrum transformation noticed in other parts of Western Europe is also encountered in Bordeaux. 83 p. 100 are affected by zoo-a... | 539,698 | [
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[Lipids and lipopolysaccharides of "Micrococcus radiodurans" (author's transl)]. | Studies were carried out on lipid composition of Micrococcus radiodurans. The polar lipid components were found to be 4 glycolipids, 3 phospholipids and 2 phosphoglycolipids. The major fraction belongs to the last group. Correlation between these components and lipoteichoic acid was not observed. A lipid-polysaccharidi... | 539,693 | [
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[Knowledge of Solomon's epidermal nevus syndrome (author's transl)]. | Solomon's epidermal nevus syndrome is a questionable entity, because of its clinical heterogeneity. Four cases are presented in this paper, with emphasis on the complex relationship between variable types of epidermal nevi and diverse kinds of associated nervous, ocular and bone abnormalities. Nevertheless, it is of pr... | 539,707 | [
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[Occurence of Onchocerca tarsicola Bain and Schulz-Key, 1974, in reindeer (author's transl)]. | Onchocerca tarsicola is recorded from reindeer (Rangifer tarandus L.). This parasite is originally described from red deer (Cervus elaphus L.). There are indications that reindeer may not be the primary host of O. tarsicola: 1. Reindeer is parasitized only by O, tarsicola whereas red deer, due to speciations, is carryi... | 539,724 | [
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A follow-up investigation of patients who have had parotid duct transplantation surgery to control drooling. | Reports concerning surgical techniques to help combat the problem of drooling not only are new and limited, but few contain postsurgical follow-up information. In this study, the parents of parotid duct transplant patients rated or described particular aspects of their child's drooling or conditions associated with the... | 539,748 | [
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Dynamic correction of intractable vaginal prolapse. | Recurrent vaginal prolapse can be very difficult to correct by simple methods. This is especially true when adequate muscle support is lacking. Scar tissues will simply not support the vagina under constant pressure, and the prolapse recurs. A new technique of diminishing vaginal size, correcting the prolapse, and then... | 539,753 | [
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Small holes, small bones, and mandibular stability. | A technique is described for drilling and wiring small bone fragments in awkward positions. It has had excellent results, especially in combination with the transfixion wiring technique. | 539,755 | [
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Restoration of frontal contour with methyl methacrylate. | Of the various materials currently available for reconstruction of bony frontal deformities, bone cement (methyl methacrylate) has been judged to be superior in its simplicity, reliability, and aesthetic potential. It is uniquely suited to reconstruction of irregular defects of the forehead. Its biological characterist... | 539,759 | [
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0.2232168,
0.3132534,
0.147589,
0.00320489... |
Furunculosis of salmonids: vaccination attempts in rainbow trout (Salmo gairdneri) by formalin-killed germs. | Two immunization trials were performed in rainbow trout, using a formalin killed Aeromonas salmonicida suspension. In the first experiment, 200 g fish were administered orally or intraperitoneally. Circulating antibodies were elicited in injected animals only, but no protection was found when they were challenged with ... | 539,775 | [
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Changes in serum succinyltrialanine p-nitroanilide hydrolysing activity in hepatobiliary diseases. | Serum succinyltrialanine p-nitroanilide hydrolysing activity was elevated in patients with hepatobiliary diseases. The highest activities were seen in acute cholangitis and intrahepatic cholestasis. The change in succinyltrialanine p-nitroanilide hydrolysing activity was closely associated with those in gamma-glutamylt... | 539,792 | [
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0.09140899,
0.1178551,
0.1404045,
-0.1561293,
-0.2616643,
-0.05417819... |
Latissimus dorsi flap-a practical approach. | The value of the latissimus dorsi flap in its various modalities is illustrated. The practical aspects of planning, raising, transferring and monitoring the flap are discussed. | 539,810 | [
-0.1384501,
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... |
Occurrence of Naegleria and Acanthamoeba in aquaria. | Samples from 24 aquaria were incubated at 28, 37, and 45 degrees C for the isolation of Naegleria and Acanthamoeba. Naegleria was the predominant genus (60.9%), whereas Acanthamoeba represented 15.5% of the isolates. No pathogenic N. fowleri was identified, although a high number of strains were closely related to this... | 539,818 | [
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... |
Enzyme recruitment allows the biodegradation of recalcitrant branched hydrocarbons by Pseudomonas citronellolis. | Experiments were carried out to construct pseudomonad strains capable of the biodegradation of certain recalcitrant branched hydrocarbons via a combination of alkane and citronellol degradative pathways. To promote the metabolism of the recalcitrant hydrocarbon 2,6-dimethyl-2-octene we transferred the OCT plasmid to Ps... | 539,823 | [
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0.124396,
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0... |
Translocation, distribution, and environmental degradation of hexachlorophene in tomatoes. | The translocation, distribution, metabolism and environmental degradation of hexachlorophene were investigated in tomato plants (Lycopersicon esculentum Mill cv. beefsteak). All plants were grown under standardized conditions and treated with leaf-applied 14C-ring-labeled hexachlorophene (HCP). Treatment time ranged fr... | 539,832 | [
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The development of Onchocerca volvulus in two temperate blackfly species, Simulium ornatum Meigen and Simulium lineatum Meigen. | In view of the promise shown by temperate simuliids for laboratory colonization, the ability of Simulium ornatum and S. lineatum to support the development of Onchocerca volvulus was investigated. An injection technique is described for the introduction of O. volvulus microfilariae from a chimpanzee into female simulii... | 539,857 | [
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... |
Polyacrilamide gel electrophoretic pattern of umbilical cord and maternal sera. | A comparative study was performed of the polyacrylamide gel electrophoretic patterns of proteins in 100 sera from the umbilical cord and maternal sera after normal pregnancies and deliveries. To simplify this analysis, the electrophoretic pattern was arbitrarily divided into nine regions that were studied according to ... | 539,861 | [
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0.1898239,
0.4128541,
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[Eradication of Candida from a premature infant unit]. | To eradicate Candida from a neonatal unit the authors used increasingly strigent protocols of prophylaxis and treatment. Finally all carriers were identified and treated with nystatin. A strict routine for washing hands was introduced. As a result of these measures the cross infection rate within the hospital was very ... | 539,869 | [
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0.1643916,
... |
[Neonatal purulent pericarditis. Value of echocardiography and surgical drainage]. | Five neonates are described who developed purulent pericarditis during a septicaemia which suggest that this is not a rare complication. The diagnosis is difficult as classical clinical, ECG and radiological signs are usually absent. Rapid enlargement of the cardiac silhouette or just cardiomegaly in the presence of a ... | 539,870 | [
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0.05208949,
... |
[Normal values of total serum IgE in children from birth to 16 years of age]. | Total serum IgE values were measured by solid phase radio-immunoassay in 250 normal children, 129 females and 121 males, whose ages ranged from birth to 16 years. IgE is not present in cord blood in contrast to the high maternal values but thereafter levels increase in a linear manner (y = 2.28 + 5.43 x, n = 250, r = 0... | 539,872 | [
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Fine structural localization of endogeneous peroxidase in the endostyle of ascidians, Ciona intestinalis. A part of phylogenetic studies of the thyroid gland. | The fine structural localization of peroxidase activity in the endostyle of Ciona intestinalis was studied by cytochemistry at electron microscopic level. Only zone 7 cells in this organ are positive for this enzyme activity. The reaction product is recognized in the external surface of the apical plasma membrane, and ... | 539,887 | [
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0.3668742,
0.4013806,
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... |
A comparison of fatty acid patterns of arterial plasma, pericardial fluid and cardiac lymph in dog. | The fatty acid composition of cardiac lymph and pericardial fluid in anesthetized open-chest dogs, was analysed and compared with that of arterial plasma. The fatty acid content of triglyceride (TG) and total fatty acid fractions of pericardial fluid and cardiac lymph was significantly lower than that of plasma. On the... | 539,915 | [
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0.02717588,
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0.1480335,
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Interaction of alpha-thalassemia genes with each other and with HbC in an American black family. | The relative rates of in vitro synthesis of hemoglobin chains have been studied in an American black family in which the mother is doubly heterozygous for alpha-thalassemia and HbC and the father is heterozygous for alpha-thalassemia. The alpha/non-alpha synthetic ratio was equally unbalanced in both the bone marrow an... | 539,999 | [
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0.2490522,
0.1684842,
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Human salivary proline-rich (Pr) proteins: a posttranslational derivation of the phenotypes. | The acidic proline-rich proteins (Pr) showing genetic polymorphism were purified from human parotid salivas by gel filtration and ion exchange chromatography. Molecular weight determinations, amino acid composition analyses, and polypeptide mapping experiments indicate that the Pr 3 protein is a fragment of the Pr 1 pr... | 540,000 | [
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Evaluation of biotin responsiveness in cultured fibroblasts from patients with propionic acidemia: absence of response by structurally altered carboxylases. | We have demonstrated that, although propionyl CoA carboxylase (PCC) activity is deficient in fibroblast extracts from PCC-deficient patients belonging to the two major and two minor genetic complementation groups, the activity of another biotin-dependent carboxylase, beta-methylcrotonyl CoA carboxylase (betaMCC), is no... | 540,014 | [
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Developmental expression of murine HPRT. I. Activities, heat stabilities, and electrophoretic mobilities in adult tissues. | Total and specific activity of the enzyme hypoxanthine phosphoribosyltransferase (HPRT) varied widely among six tissues from C3H/f mice; the highest levels of activity were in brain. More striking were thermostability differences in tissue enzymes. Although brain, spleen, and kidney HPRT retained 65% basal activity aft... | 540,017 | [
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The purification and characterization of subcomponent C1s of the first component of bovine complement. | Bovine C1s, a subcomponent of the first component of complement, was purified in good yield by a combination of euglobulin precipitation and ion-exchange and molecular-sieve chromatography. Approx. 10 mg can be obtained from 3 litres of serum, representing a yield of 11%. The C1s is obtained in zymogen form, with a mol... | 540,032 | [
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A new series of long-chain dicarboxylic acids with vicinal dimethyl branching found as major components of the lipids of Butyrivibrio spp. | 1. Some members of the genus Butyrivibrio, including a general fatty acid auxotroph (strain S2), contain as a major part of their complex lipids a high-molecular-weight component that is probably formed by the union of two fatty acid chains [Hazlewood & Dawson (1979) J. Gen. Microbiol. 112, 15--27]. 2. Proton and 1... | 540,040 | [
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... |
[Nicergoline and platelet aggregation. A review of experimental and clinical studies (author's transl)]. | 10-Methoxy-1,6-dimethyl-ergoline-8 beta-methanol-(5-bromonicotinate) (nicergoline, Sermion), an ergoline derivative in clinical use for syndromes related to cerebral and peripheral vascular insufficiency, displays a platelet antiaggregating effect which may be important for its therapeutic effect. This paper reviews th... | 540,070 | [
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Resorption of insoluble, heterologous, fluorescein-collagen sponges in sensitized and non-sensitized rats. | Sponges of insoluble bovine collagen were slowly resorbed over a 35-day period when implanted under the back skin of rats. The cellular picture was typical of a mild foreign-body reaction. The reaction to fluorescein-labelled collagen sponges was similar but there was evidence also of a weak immunological response. An ... | 540,096 | [
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0.2168604,
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The histopathology and ultrastructure of pleural mesotheliomas produced in the rat by injections of crocidolite asbestos. | Primary tumours of the pleural cavity were produced in rats by the intrapleural injection of crocidolite asbestos. Their histological structure as seen with both light and electron microscopy was very variable and tumours frequently contained elements of both connective-tissue and epithelial type. In some instances the... | 540,105 | [
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0.4318903,
0.3815362,
-0.02124419... |
[Basophil "degranulation" as an index of the body stress state]. | A regular "degranulation" development of basophilic leucocytes in the blood has been established not only in cases of the joint and skin allergic reactions but in acute and chronic experimental hemorrhage, skin burns and acute radiation disease. Basophilic "degranulation" denotes the stress state of the organism as a r... | 540,155 | [
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0.3615647,
0.3251934,
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0.0472689... |
[Mechanical device for morphological and orientation analysis of biological structures]. | A simple mechanical device for different kinds of morphological analysis is suggested. It consists of a binocular microscope, a luminiscent illuminator, a coordination table with a disc-chuck (0-360 degrees) and a nest for disposing the test systems and the light or electronmicroscopic negatives (6 x 9 and 9 x 12). The... | 540,159 | [
0.1034948,
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0.3422063,
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0.03873989,
0.08... |
2,3-butanedione as a photosensitizing agent: application to alpha-amino acids and alpha-chymotrypsin. | 2,3-Butanedione sensitized the rapid photodestruction of free alpha-amino acids, and the photoinactivation of alpha-chymotrypsin, in the presence of ultraviolet light and oxygen. These reactions showed "pseudo-first-order" kinetics at 2,3-butanedione concentrations approximating those employed for the chemical modifica... | 540,238 | [
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0.1545802,
0.2204422,
0.373032,
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0.23648... |
Investigations on the photosynthetic sulfur bacterium Chlorobium phaeobacteroides causing seasonal blooms in Lake Kinneret. | Between May and December, the annual stratification period in Lake Kinneret, sulfide is formed and accumulates in the hypolimnion. In July-August a large population (up to 10(6) cells/mL) of green, photosynthetic, sulfur bacteria develops at the boundary of the oxidative and reductive zones of the water column lasting ... | 540,269 | [
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0.5196464,
0.1634474,
0.5367925,
0.4413631,
-0.01022884... |
[Validity of retrograde peripheral phlebography (author's transl)]. | The Authors present and discuss the results obtained in phlebographic exploration by a particular method, namely retrograde peripheral phlebography. After describing the technicalities of this procedure, they evaluated its advantages and disadvantages, and conclude by recommending a more widespread use of this examinat... | 540,365 | [
0.1029267,
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0.08922431,
0.01251336,
0.1350807,
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0.012529... |
[Primary closure of the perineum after Miles's abdominoperineal amputation for carcinoma of the rectum (author's transl)]. | In view of the results obtained in 32 cases of primary closure of the perineum after amputation of the rectum for cancer, the authors believe that this policy is best after removal of the malignancy by the abdominoperineal approach. Unquestionable advantages are shortening of the patient's hospital stay and a more rapi... | 540,371 | [
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0.1886792,
-0.1040887,
0.1454... |
[Coloportal fistula in ulcerative colitis (massive penetration, through the splenic vein, of barium and air into the portal system during barium enema)]. | The authors describe one case of massive penetration of barium and air through the splenic vein into the portal system during administration of a radiopaque enema to a woman suffering from hemorrhagic proctitis in the florid phase. They provide a detailed description of this rare clinical case and discuss the possible ... | 540,383 | [
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0.05516817,
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0.4534907,
0.0863554,
0.1127166,
0.0... |
The ratio between thickness of media and internal radius in cerebral, mesenteric and renal arterial vessels in spontaneously hypertensive rats. | 1. Larger arterial vessels of 15-day-old spontaneously hypertensive (SH) rats showed significantly greater media/internal radius ratio than those of Wistar-Kyoto rats in the brain, kidney and mesentery. 2. Since larger cerebral and renal arteries of adult SH rats did not differ from controls the above results indicate ... | 540,441 | [
-0.2959699,
0.1435861,
0.09589893,
-0.04236371,
0.4683084,
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0.06023968,
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0.09151895,
0.2647677,
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0.07946195,
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0.2019897,
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-0.08694091,
0.1041151,
0.1062462,
0.1856472,
... |
Biochemical alterations of connective tissue metabolism in the arterial walls of stroke-prone spontaneously hypertensive rats. | 1. The chemical characteristics of the vascular connective tissue components were determined in stroke-prone (SP), stroke-resistant (SR) spontaneously hypertensive (SH) rats and normotensive Wistar-Kyoto (WK) rats. 2. The ratio of hydroxylysine to hydroxylsine plus lysine in the vascular collagen was increased in 6-mon... | 540,454 | [
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0.04421059,
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0.2820244,
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0.02947891,
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0.2262152,
-0.008604134,
0.3488442,
0.2953705,
0.2434076,
-0.1649653,
0.... |
Protein synthesis and composition of cardiac and vascular tissue in spontaneously hypertensive rats and the effects of beta-adrenergic antagonist treatment. | 1. Propranolol and metoprolol were given in the diet of spontaneously hypertensive (SH) rats during the development of hypertension. 2. At the early established phase of hypertension, protein synthesis and protein composition of the left ventricle, aorta, mesenteric artery and vena cava were measured. 3. The left ventr... | 540,458 | [
0.02337194,
0.1494262,
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0.2544808,
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0.005206074,
0.2751299,
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0.1668102,
0.1003094,
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-0.3099256,
0.09931131,
0.03878511,
0.3098967,
0.1517918,
0.1372164,
-0.2841681,
... |
Action of clonidine on centrally evoked salivation in anaesthetized cats. | 1. Clonidine (4 microgram/kg) given intracisternally to anaesthetized cats inhibited brain stem-evoked parasympathetic submaxillary or parotid salivation by 62% at 5 Hz and 44% at 15 Hz. 2. The inhibitory action of clonidine on salivation was equally prevented by pretreatment with either intracisternal yohimbine (175 m... | 540,464 | [
0.004254773,
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0.02694809,
-0.1539081,
0.07442591,
0.2381802,
0.11064... |
Lateralized psychological impairment associated with CT lesions in head injured patients. | Twenty-six adult patients with CT scans were given the Wechsler Adult Intelligence Scale (WAIS) during recovery from an acute head injury. Focal lesions were observed on the initial CT scans of 24 patients. These included 13 in the right hemisphere, 8 in the left hemisphere and 3 in both hemispheres. Diffuse cerebral s... | 540,511 | [
-0.2193266,
0.05355529,
0.2287523,
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0.2758613,
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-0.3394067,
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0.06279171,
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-0.06485502,
0.1343121,
-0.2022778,
0.04042291,
-0.06650471,
0.2512943,
-0.0534807... |
Articulatory and phonological aspects of consonant substitutions in apraxia of speech. | The articulatory and distinctive features in 825 consonant substitutions produced by nine subjects with apraxia of speech were analyzed. The articulatory and distinctive features of the target consonants were retained beyond chance levels. The substitution patterns observed were very systematic in that more substitutio... | 540,515 | [
-0.3220461,
0.2242478,
0.1633587,
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0.278902,
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0.1179974,
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0.09785649,
-0.2660166,
0.044855,
-0.004018253,
-0.2199047,
0.3710398,
0.02769009,
-0.05958127,... |
Xanthinol nicotinate in the management of leg ulcers associated with haemoglobinopathies. | The therapeutic role of xanthinol nicotinate, with its potent action on the peripheral circulation, in promoting healing of leg ulcers when added to conservative measures of ulcer treatment in adult beta-thalassaemia major and sickle cell thalassaemia, was evaluated in a double-blind crossover trial in 16 patients suff... | 540,521 | [
-0.08861917,
0.3443989,
-0.1133081,
-0.241722,
-0.03788038,
-0.3671568,
0.004585996,
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0.08655061,
-0.2602487,
0.1437131,
0.1624718,
-0.09645699,
0.1580781,
-0.2990953,
-0.1633158,
0.01210952,
-0.2487618,
-0.3165682,
0.01369423,
-0.0261496,
0.2876453,
-0.1587382... |
Clobetasone butyrate compared with betamethasone valerate in the treatment of atopic and contact dermatitis. | In a double-blind, randomized study, 0.05% clobetasone butyrate cream was found to be as effective as 0.1% betamethasone valerate in the treatment of 48 patients with atopic or contact dermatitis, after 2 weeks as well as after 4 weeks of treatment. Side-effects with both drugs were rare and mild. | 540,522 | [
-0.03137467,
0.1116668,
-0.006241558,
0.08562602,
0.009249655,
-0.2610588,
-0.3773518,
-0.1177907,
-0.07836547,
-0.02964357,
-0.07400557,
0.2106511,
0.1089732,
0.04405884,
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-0.2827379,
-0.2649124,
0.4294011,
-0.1983096,
0.2310425,
0.004226353,
0.4023065,
-0.064... |
A fixed combination of metoprolol and hydrochlorothiazide for hypertension: a multi-centre study. | A multi-centre, open study was carried out in 140 hypertensive patients to investigate the hypotensive effect of 2 tablets of a fixed combination of 100 mg metoprolol plus 12.5 mg hydrochlorothiazide when taken either once-daily or twice-daily, each for 4 weeks. Blood pressure and pulse rate measurements were taken at ... | 540,527 | [
-0.4021868,
0.3976837,
-0.21749,
0.1292564,
0.1860187,
-0.3238963,
-0.5741516,
-0.07114276,
0.03103651,
-0.1972049,
0.0211107,
0.2478373,
-0.0246094,
0.08482198,
-0.29492,
-0.07390356,
-0.225175,
0.2525782,
-0.2272172,
0.170464,
-0.1836389,
0.1152597,
-0.1410395,
0.0387... |
Differential effects of prostaglandin F2 alpha on oxytocinergic and non-oxytocinergic neurones in the paraventricular nucleus of the lactating rat. | The effects of the prostaglandin F2 alpha (PGF2 alpha) given into the third cerebral ventricle on the unit activity of neurosecretory neurones in the paraventricular nucleus (PVN) were studied in urethane-anesthetized rats. The firing activity of PVN neurones was recorded extracellularly and 50 neurones were antidromic... | 540,572 | [
-0.1125029,
-0.08858269,
-0.05693879,
-0.4212644,
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-0.2405161,
0.06994878,
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0.104204,
0.1486074,
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-0.05128779,
0.2942926,
-0.01002178,
-0.05227425,
0.04459822,
0.1830469,
0.18635... |
Discussion of Tanaka's paper. | The theory of quantification is a method of statistical data analysis of categorical data. In other words, this is a kind of data theory and is closely related to optimum scaling method. This method has been mainly developed by Guttman in Israel and Hayashi in Japan. The multidimensional scaling method, which has been ... | 540,586 | [
0.03233334,
0.07338595,
-0.1068536,
-0.1814231,
0.1661307,
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0.08303221,
0.1731155,
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-0.7170745,
0.1652924,
0.06831416,
0.2686182,
-0.3925399,
0.06226236,
0.1331652,
0.2692761,
0.255536,
0.2... |
Normal and abnormal intestinal absorption by humans. | Adults eating a Western diet digest and absorb ingested food containing approximately 100 g fat, 350 g carbohydrate, and 75 g protein daily. Normal fat absorption requires adequate gastric, pancreatic, liver-biliary, mucosal, and lymphatic function. Carbohydrate and protein absorption is much less dependent on liver-bi... | 540,610 | [
0.1263215,
-0.4329614,
0.009157815,
0.1757443,
0.319416,
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-0.04317899,
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-0.03915325,
0.1097626,
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0.2518896,
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-0.4414728,
0.07951533,
-0.06155701,
0.2170062,
0.1061553,
0.4251792,
0.00755205... |
Health effects of coal mining and combustion: carcinogens and cofactors. | Some polynuclear aromatics (PNA) have been found to be potent carcinogens for all tissues and organs of experimental animals that have been exposed to them, but different dose levels are needed for these effects. They have been known for decades to cause cancer at the site of application but also at certain sites dista... | 540,618 | [
-0.1934859,
-0.1869343,
0.01509037,
0.1191072,
0.1724074,
-0.02542364,
0.1519697,
0.3193977,
0.07038998,
0.1402051,
-0.3721519,
-0.3484333,
0.3233642,
-0.6227787,
-0.865548,
-0.06647435,
-0.1538934,
-0.1079257,
0.2846311,
0.1813933,
-0.08623236,
0.2482263,
-0.2774607,
-... |
Economic importance of breastfeeding. | While an increasing body of research has documented the importance of breastfeeding for infant health, very little research has been done on its economic implications. From an economic perspective, breast milk can in many respects be regarded like any other food commodity. For example, it could be stored in milk banks,... | 540,668 | [
0.05381949,
0.1317577,
0.007372472,
0.2467441,
0.04719527,
0.1154186,
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-0.1479314,
-0.01043392,
-0.02867747,
0.1109466,
-0.3292227,
-0.183317,
-0.1446923,
-0.1703616,
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-0.3364426,
0.1394139,
-0.239567,
-0.2446693,
0.361787,
0.3151499,
0.02955768,
... |
Clonidine and carotid baroreflex in essential hypertension. | Clonidine is believed to reduce blood pressure by a neural action and animal experiments suggest that this consists in potentiation of baroreflexes. In 16 patients with essential hypertension we studied the effects of alterations in carotid sinus baroreceptor activity (neck chamber technique) on arterial blood pressure... | 541,039 | [
0.01700091,
-0.01541968,
-0.6929253,
-0.1154441,
0.2026543,
-0.4284611,
-0.169069,
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0.02634726,
-0.006370358,
0.09803139,
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0.1661965,
0.009402793,
-0.1857148,
-0.1498675,
-0.5375451,
0.09657823,
-0.2157619,
0.2300382,
0.1983957,
-0.1337837,
0.1661918... |
Blood pressure in childhood. The National Health Examination Survey. | Data were analyzed from the U.S. Health Examination Survey (Cycle II) to determine relationships between blood pressure and other characteristics. This survey examined a national probability sample of children aged 6-11 years. Significant relationships were found for blood pressure and the following variables: chronolo... | 541,048 | [
-0.2782943,
-0.1892425,
-0.2867746,
-0.1876469,
0.1290417,
-0.05584111,
-0.359592,
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0.2731484,
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0.2662024,
-0.3472349,
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0.120502,
0.07503974,
0.002558471,
0.01543312,
0.3225213,
-0.04497218,
-0.2573052,
... |
[The behavior of the facial nerve in vitamin A and thalidomide induced atresia auris congenita. A microsurgical and histological animal study (author's transl)]. | Atresia auris congenita may include either a complete or incomplete paralysis of the facial nerve as well as a possible abnormal course of its tympanic segment. Pregnant Wistar rats were given high doses (50,000, 80,000 or 100,000 USP units) of vitamin A and (10,15 or 20 mg) Thalidomide on the 8th, 9th, 10th and 11th d... | 541,231 | [
0.01626315,
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0.06656339,
0.1955232,
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0.3637922,
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0.02553486,
-0.1134215,
-0.1717325,
0.5680281,
-0.04411851,
0.004668592,
... |
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