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9394 | 0 | Title: Hypericum perforatum and Its Ingredients Hypericin and Pseudohypericin Demonstrate an Antiviral Activity against SARS-CoV-2. Abstract: For almost two years, the COVID-19 pandemic has constituted a major challenge to human health, particularly due to the lack of efficient antivirals to be used against the virus d... |
898 | 0 | Title: Political Secularism and Muslim Integration in the West: Assessing the Effects of the French Headscarf Ban. Abstract: In response to rising immigration flows and the fear of Islamic radicalization, several Western countries have enacted policies to restrict religious expression and emphasize secularism and Weste... |
2398 | 0 | Title: Case fatality risk of the SARS-CoV-2 variant of concern B.1.1.7 in England, 16 November to 5 February. Abstract: The SARS-CoV-2 B.1.1.7 variant of concern (VOC) is increasing in prevalence across Europe. Accurate estimation of disease severity associated with this VOC is critical for pandemic planning. We found ... |
5906 | 0 | Title: Realized Volatility Forecasting with Neural Networks. Abstract: Abstract In the last few decades, a broad strand of literature in finance has implemented artificial neural networks as a forecasting method. The major advantage of this approach is the possibility to approximate any linear and nonlinear behaviors w... |
2343 | 1 | Title: Evidence-based prevention of Alzheimer's disease: systematic review and meta-analysis of 243 observational prospective studies and 153 randomised controlled trials. Abstract: Evidence on preventing Alzheimer's disease (AD) is challenging to interpret due to varying study designs with heterogeneous endpoints and ... |
2343 | 2 | Twenty-one suggestions are proposed based on the consolidated evidence, with Class I suggestions targeting 19 factors: 10 with Level A strong evidence (education, cognitive activity, high body mass index in latelife, hyperhomocysteinaemia, depression, stress, diabetes, head trauma, hypertension in midlife and orthostat... |
8225 | 0 | Title: Collaboration, Co-Optation or Navigation? The Role of Civil Society in Disaster Governance in India. Abstract: Abstract Existing research on civil society organizations (CSOs) facing restricted civic space largely focuses on the crackdown on freedoms and CSOs’ strategies to handle these restrictions, often empha... |
5506 | 0 | Title: Implication of backward contact tracing in the presence of overdispersed transmission in COVID-19 outbreak. Abstract: Abstract Unlike forward contact tracing, backward contact tracing identifies the source of newly detected cases. This approach is particularly valuable when there is high individual-level variati... |
6451 | 1 | Title: Army ants dynamically adjust living bridges in response to a cost–benefit trade-off. Abstract: The ability of individual animals to create functional structures by joining together is rare and confined to the social insects. Army ants (Eciton) form collective assemblages out of their own bodies to perform a vari... |
6451 | 2 | We then constructed a model to determine the bridge location that maximized foraging rate, which qualitatively matched the observed movement of bridges. Our results highlight how animal self-assemblages can be dynamically modified in response to a group-level cost-benefit trade-off, without any individual unit's having... |
2670 | 0 | Title: Words without meaning. Abstract: Many of the words used by scientists when reviewing manuscripts, job candidates and grant applications – words such as incremental, novelty, mechanism, descriptive and impact – have lost their meaning.. |
3497 | 1 | Title: Does Stretching Training Influence Muscular Strength? A Systematic Review With Meta-Analysis and Meta-Regression. Abstract: Abstract Thomas, E, Ficarra, S, Nunes, JP, Paoli, A, Bellafiore, M, Palma, A, and Bianco, A. Does stretching training influence muscular strength? A systematic review with meta-analysis and... |
3497 | 2 | The interventions lasted for a mean period of 8 weeks (range, 4–24 weeks), 3–4 days per week, applying approximately 4 sets of stretching of approximately 1-minute duration. The meta-analysis for the stretching vs. nontraining control group showed a significant small effect on improving dynamic (k = 14; ES = 0.33; p = ... |
3497 | 3 | Chronic static stretching programs increase dynamic muscular strength to a small magnitude. Performing stretching before RT and for a prolonged time (>8 weeks) can blunt the strength gains to a small-to-moderate magnitude. Performing stretching in sessions distant from RT sessions might be a strategy to not hinder stre... |
1087 | 1 | Title: The structure, function and evolution of a complete human chromosome 8. Abstract: Abstract The complete assembly of each human chromosome is essential for understanding human biology and evolution 1,2 . Here we use complementary long-read sequencing technologies to complete the linear assembly of human chromosom... |
1087 | 2 | Using a dual long-read sequencing approach, we complete high-quality draft assemblies of the orthologous centromere from chromosome 8 in chimpanzee, orangutan and macaque to reconstruct its evolutionary history. Comparative and phylogenetic analyses show that the higher-order α-satellite structure evolved in the great ... |
1819 | 1 | Title: Treatment Emergent Violence To Self And Others; A Literature Review of Neuropsychiatric Adverse Reactions For Antidepressant And Neuroleptic Psychiatric Drugs And General Medications.. Abstract: This paper reviews the literature linking physical violence, directed towards self or others, to serotonergic and dopa... |
1819 | 2 | Phase 1 metabolism takes place via the cytochrome P450 enzymes with 57 human genes identified that are genetically variable i.e. polymorphic. The population are coded as poor, extensive (known as normal), intermediate or ultra rapid metabolisers. Variations in the serotonin transporter gene (5-HTTLPR) and serotonin rec... |
1819 | 3 | These issues indicate a need for greater pharmaceutical transparency and further research into the role of CYP450, 5-HTTLPR and 5-HT polymorphism associated neuropsychiatric ADRs for all psychiatric drugs and serotonergic general medications.Safer prescribing is important and could be achieved by individual genotype te... |
2308 | 1 | Title: SARS-CoV-2 vaccination and myocarditis or myopericarditis: population based cohort study. Abstract: AbstractObjective To investigate the association between SARS-CoV-2 vaccination and myocarditis or myopericarditis. Design Population based cohort study. Setting Denmark. Participants 4 931 775 individuals aged 12... |
2308 | 2 | Results During follow-up, 269 participants developed myocarditis or myopericarditis, of whom 108 (40%) were 12-39 years old and 196 (73%) were male. Of 3 482 295 individuals vaccinated with BNT162b2 (Pfizer-BioNTech), 48 developed myocarditis or myopericarditis within 28 days from the vaccination date compared with unv... |
2308 | 3 | Adjusted hazard ratios among female participants only and male participants only were 3.73 (1.82 to 7.65) and 0.82 (0.50 to 1.34), respectively, with corresponding absolute rates of 1.3 (0.8 to 1.9) and 1.5 (1.0 to 2.2) per 100 000 vaccinated individuals within 28 days of vaccination, respectively. The adjusted hazard ... |
2308 | 4 | Among 498 814 individuals vaccinated with mRNA-1273 (Moderna), 21 developed myocarditis or myopericarditis within 28 days from vaccination date (adjusted hazard ratio 3.92 (2.30 to 6.68); absolute rate 4.2 per 100 000 vaccinated individuals within 28 days of vaccination (2.6 to 6.4)). Adjusted hazard ratios among women... |
2308 | 5 | The adjusted hazard ratio among 12-39 year olds was 5.24 (2.47 to 11.12) and the absolute rate was 5.7 (3.3 to 9.3) per 100 000 vaccinated individuals within 28 days of vaccination. Conclusions Vaccination with mRNA-1273 was associated with a significantly increased risk of myocarditis or myopericarditis in the Danish ... |
6084 | 1 | Title: Molnupiravir Use and 30-Day Hospitalizations or Death in a Previously Uninfected Nonhospitalized High-risk Population With COVID-19. Abstract: Abstract Background Clinical benefit of molnupiravir (MPV) in coronavirus disease 2019 (COVID-19)–infected subpopulations is unclear. Methods We used a matched cohort stu... |
6084 | 2 | No benefit was observed among those >60 or ≤60 years old (ARD, 0.27; 95% CI, −1.25 to 1.79 vs ARD, −0.29; 95% CI, −1.22 to 1.80), those with specific comorbidities, or by vaccination status. A significant benefit was observed in asymptomatic but not in symptomatic persons (ARD, −2.80; 95% CI, −4.74 to −.87 vs ARD, 1... |
3724 | 1 | Title: Pediatric Minimal Change Disease and AKI following the Pfizer-BioNTech COVID-19 Vaccine: causal or incidental correlation?. Abstract: The global coronavirus 2019 (COVID-19) pandemic required vaccination even in children to reduce infection. We report on the development of acute kidney injury (AKI) and minimal ch... |
3724 | 2 | Seven days after steroid therapy, kidney function began to improve, gradually returning to normal. The association of MCD, nephrotic syndrome and AKI hasn't been previously described following the Pfizer-BioNTech COVID-19 vaccine in pediatric population, but this triad has been reported in adults. We need further simil... |
3184 | 1 | Title: Kidney Single-Cell Atlas Reveals Myeloid Heterogeneity in Progression and Regression of Kidney Disease. Abstract: Significance Statement The innate immune system is central to injury and repair in the kidney, but the heterogeneity of myeloid cell subsets behind these processes is unknown. Complementary technolog... |
3184 | 2 | Defining these cells at the single-cell, transcriptomic level could reveal myeloid heterogeneity in the progression and regression of kidney disease. Methods Integrated droplet– and plate-based single-cell RNA sequencing were used in the murine, reversible, unilateral ureteric obstruction model to dissect the transcrip... |
6387 | 1 | Title: The role of social circle COVID-19 illness and vaccination experiences in COVID-19 vaccination decisions: an online survey of the United States population. Abstract: Abstract Background Around the world, policymakers have clearly communicated that COVID-19 vaccination programs need to be accepted by a large prop... |
6387 | 2 | Results A total of 2840 participants completed the survey between December 18 and 23, 2021. 51% (1383 of 2840) of the participants were female and the mean age was 47 (95% CI 46.36–47.64) years. Those who knew someone who experienced a health problem from COVID-19 were more likely to be vaccinated (OR: 1.309, 95% CI 1.... |
6387 | 3 | With these survey data, the total number of fatalities due to COVID-19 inoculation may be as high as 278,000 (95% CI 217,330–332,608) when fatalities that may have occurred regardless of inoculation are removed. Conclusion Knowing someone who reported serious health issues either from COVID-19 or from COVID-19 vaccinat... |
3728 | 1 | Title: A Survey and Analysis of TLS Interception Mechanisms and Motivations: Exploring how end-to-end TLS is made “end-to-me” for web traffic. Abstract: TLS is an end-to-end protocol designed to provide confidentiality and integrity guarantees that improve end-user security and privacy. While TLS helps defend against p... |
3728 | 2 | Finally, we compare each scheme based on deployability and security characteristics, and evaluate their compatibility with the stakeholders' incentives. Our analysis leads to a number of key findings, observations, and research questions that we believe will be of interest to practitioners, policy makers and researcher... |
2702 | 0 | Title: SARS-CoV-2 RNA levels in Scotland’s wastewater. Abstract: Abstract Nationwide, wastewater-based monitoring was newly established in Scotland to track the levels of SARS-CoV-2 viral RNA shed into the sewage network, during the COVID-19 pandemic. We present a curated, reference data set produced by this national p... |
7883 | 0 | Title: Black Lives Matter's Effect on Police Lethal Use-of-Force. Abstract: How has Black Lives Matter (BLM) influenced police lethal force? An event study design finds census places with early BLM protests experienced a 10% to 15% decrease in police homicides from 2014 through 2019, around 200 fewer deaths. This decre... |
2930 | 0 | Title: The newly introduced SARS-CoV-2 variant A222V is rapidly spreading in Lazio region, Italy. Abstract: Abstract A new SARS-CoV-2 clade (GV) characterized by S substitution A222V, first reported from Spain in March, is rapidly spreading across Europe. To establish the A222V variant involvement in the infection rise... |
5988 | 1 | Title: Super high-pressure balloon versus scoring balloon to prepare severely calcified coronary lesions: the ISAR-CALC randomised trial. Abstract: The comparative efficacy of balloon-based techniques to prepare severely calcified coronary lesions before stenting remains poorly studied.We sought to compare stent expans... |
5988 | 2 | Lesion preparation with a super high-pressure balloon versus a scoring balloon led to a comparable stent expansion index (0.72±0.12 vs 0.68±0.13; p=0.22). Compared with the scoring balloon, the super high-pressure balloon increased the minimum lumen diameter (2.83±0.34 mm vs 2.65±0.36 mm; p=0.03) and reduced the diamet... |
5988 | 3 | Strategy success (91.9% vs 83.8%; p=0.48) and procedural success (100% vs 89.2%; p=0.12) were numerically more frequent with the super high-pressure balloon versus the scoring balloon.In patients with severely calcified coronary artery lesions, preparation with a super high-pressure balloon versus a scoring balloon was... |
4890 | 0 | Title: The UK government’s covid complacency shows lessons haven’t been learned. Abstract: This week, England’s health secretary, Sajid Javid told a Downing Street covid briefing that the government would not “at this point” be implementing its so-called “Plan B” measures to prevent the NHS being overwhelmed—including ... |
6718 | 1 | Title: SARS-CoV-2 Infections and Serologic Responses from a Sample of U.S. Navy Service Members — USS Theodore Roosevelt, April 2020. Abstract: Compared with the volume of data on coronavirus disease 2019 (COVID-19) outbreaks among older adults, relatively few data are available concerning COVID-19 in younger, healthy ... |
6718 | 2 | Service members who reported taking preventive measures had a lower infection rate than did those who did not report taking these measures (e.g., wearing a face covering, 55.8% versus 80.8%; avoiding common areas, 53.8% versus 67.5%; and observing social distancing, 54.7% versus 70.0%, respectively). The presence of ne... |
5423 | 1 | Title: New-Onset Systemic Lupus Erythematosus after mRNA SARS-CoV-2 Vaccination. Abstract: Systemic lupus erythematosus (SLE) is a multisystem autoimmune disease resulting from the interaction of genetic and environmental factors. In addition, some antiviral vaccines have been associated with the onset of SLE. Few case... |
5423 | 2 | Subsequently, mycophenolate mofetil was added after she developed proteinuria. This case highlights the importance of considering the diagnosis of SLE in patients who present with inflammatory polyarthritis after COVID-19 vaccination.. |
3213 | 1 | Title: A Sustainable and Global Health Perspective of the Dietary Pattern of French Population during the 1998–2015 Period from INCA Surveys. Abstract: In France, the evolution of dietary pattern relative to sustainability and global health remains insufficiently studied. The objective of this study was to assess dieta... |
3213 | 2 | In children, UPF daily calories increased from 42.8 to 45.5% and decreased in adults from 39.2 to 35.0%. In children and adults, diet revegetation was observed. While the level of physical activity decreased, overweight, obesity and type 2 diabetes prevalence increased in French adults. The French dietary pattern is no... |
3017 | 1 | Title: Association of Use of an Intravascular Microaxial Left Ventricular Assist Device vs Intra-aortic Balloon Pump With In-Hospital Mortality and Major Bleeding Among Patients With Acute Myocardial Infarction Complicated by Cardiogenic Shock. Abstract: Acute myocardial infarction (AMI) complicated by cardiogenic shoc... |
3017 | 2 | Patients receiving an intravascular microaxial LVAD were matched with those receiving IABP on demographics, clinical history, presentation, infarct location, coronary anatomy, and clinical laboratory data, with final follow-up through December 31, 2017.Hemodynamic support, categorized as intravascular microaxial LVAD u... |
3017 | 3 | Among 1680 propensity-matched pairs, there was a significantly higher risk of in-hospital death associated with use of an intravascular microaxial LVAD (45.0%) vs with an IABP (34.1% [absolute risk difference, 10.9 percentage points {95% CI, 7.6-14.2}; P < .001) and also higher risk of in-hospital major bleeding (intra... |
3017 | 4 | Further research may be needed to understand optimal device choice for these patients.. |
382 | 1 | Title: Fluvoxamine for outpatients with COVID-19: where do we stand?. Abstract: Advances in vaccine development have had a major effect on reducing the number of new symptomatic cases, hospitalisations, and deaths due to COVID-19, the viral disease caused by SARS-CoV-2, globally.1Tregoning JS Flight KE Higham SL Wang Z... |
382 | 2 | This is particularly true for outpatients, who comprise the largest population of individuals infected with the SARS-CoV-2, and for whom few effective therapies exist. Fluvoxamine is a selective serotonin reuptake inhibitor commonly indicated for the management of depression, obsessive-compulsive disorders, and other m... |
382 | 3 | 2021; 8ofab050Crossref PubMed Scopus (102) Google Scholar In trial results published in 2020, 152 outpatients with mild COVID-19 were randomly assigned to receive 100 mg fluvoxamine three times daily or matching placebo for 15 days.5Lenze EJ Mattar C Zorumski CF et al.Fluvoxamine vs placebo and clinical deterioration i... |
382 | 4 | Within 15 days, none of the participants who received fluvoxamine and 8·3% of those who received placebo reached the primary endpoint (absolute risk difference 8·7%; 95% CI 1·8%–16·5%; p=0·009). Despite the promising results, limitations such as low statistical power and missing data for the primary outcome precluded d... |
382 | 5 | 2021; (published online Oct 27.)https://doi.org/10.1016/S2214-109X(21)00448-4Summary Full Text Full Text PDF PubMed Scopus (217) Google Scholar A total of 1497 participants were randomly allocated to fluvoxamine, 100 mg twice daily, or matching placebo. All included participants had a positive test for SARS-CoV-2 and k... |
382 | 6 | Using a Bayesian analytical approach, the authors found that the proportion of patients reaching the primary endpoint was lower for the fluvoxamine group compared with placebo (11% vs 16%; relative risk: 0·68; 95% Bayesian credible interval 0·52–0·88), with a probability of superiority of 99·8%. The TOGETHER trial had ... |
382 | 7 | Undeniably, key factors for the success of this initiative rely on the scientific exchange between academic groups from Brazil and Canada and on the use of an adaptive, platform, randomised design. This research methodology allows simultaneous and efficient assessment of different potential therapies for COVID-19. From... |
382 | 8 | In addition, it remains to be established whether fluvoxamine has an additive effect to other therapies such as monoclonal antibodies7Yu L-M Bafadhel M Dorward J et al.Inhaled budesonide for COVID-19 in people at high risk of complications in the community in the UK (PRINCIPLE): a randomised, controlled, open-label, ad... |
382 | 9 | Finally, it is still unclear whether the results from the TOGETHER trial extend to other outpatient populations with COVID-19, including those without risk factors for disease progression, those who are fully vaccinated, and those infected with the delta variant or other variants. I declare research grants outside of t... |
4237 | 1 | Title: COVID-19 vaccines dampen genomic diversity of SARS-CoV-2: Unvaccinated patients exhibit more antigenic mutational variance. Abstract: Abstract Variants of SARS-CoV-2 are evolving under a combination of immune selective pressure in infected hosts and natural genetic drift, raising a global alarm regarding the dur... |
4237 | 2 | Given that the COVID-19 vaccines leverage B-cell and T-cell epitopes, analysis of mutation rates shows neutralizing B-cell epitopes to be particularly more mutated than comparable amino acid clusters (4.3-fold, p < 0.001). Prospective validation of these macroscale evolutionary patterns using clinically annotated SARS-... |
4721 | 1 | Title: Paleoeconomy more than demography determined prehistoric human impact in Arctic Norway. Abstract: Population size has increasingly been taken as the driver of past human environmental impact worldwide, and particularly in the Arctic. However, sedimentary ancient DNA (sedaDNA), pollen and archaeological data show... |
4721 | 2 | The rich animal sedaDNA data (42 taxa) and on-site faunal analyses reveal switches in human dietary composition from early-Holocene fish + marine mammals, to mixed marine + reindeer, then finally to marine + reindeer + domesticates (sheep, cattle, pigs), with highest reindeer concentrations in the last millennium. Arch... |
9547 | 1 | Title: Patrimonialisations de la littérature. Abstract: Parmi les domaines caractérisés par une charge patrimoniale forte, la littérature continue d’occuper une position de premier plan dans les sociétés contemporaines. Si nous connaissons la littérature du passé et lui accordons une valeur, c’est en effet dans une lar... |
9547 | 2 | L’une des principales finalités de ce dossier est d’identifier certaines des lignes de force de ce processus multiforme et de contribuer ainsi au dialogue et à la convergence de recherches émanant de champs disciplinaires restés longtemps relativement étanches, en raison de la diversité des types de discours, de médium... |
9547 | 3 | One of the main objectives of this issue is to identify the main thrusts of this multifold process and thus to contribute to the dialogue and convergence of research in fields that have long remained relatively hermetic, because of the diversity of types of discourse, media and institutions that render literature and i... |
9547 | 4 | Uno de los principales propósitos de este dossier es identificar algunas de las principales líneas de este proceso multiforme y contribuir así al diálogo y a la convergencia de las investigaciones que emanan de campos disciplinarios, que durante mucho tiempo han permanecido relativamente aislados, como consecuencia de ... |
9477 | 1 | Title: Serum Neutralizing Activity of mRNA-1273 against SARS-CoV-2 Variants. Abstract: ABSTRACT The emergence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variants has led to growing concerns over increased transmissibility and the ability of some variants to partially escape immunity. Sera from part... |
9477 | 2 | Results showed minimal effects on neutralization titers against the B.1.1.7 (Alpha) variant (1.2-fold reduction compared with D614G); other VOCs such as B.1.351 (Beta, including B.1.351-v1, B.1.351-v2, and B.1.351-v3), B.1.617.2 (Delta), and P.1 (Gamma) showed decreased neutralization titers ranging from 2.1-fold to 8.... |
4795 | 1 | Title: Multisystem Inflammatory Syndrome in Children in the United States. Abstract: 23 issue) present case series of the multisystem inflammatory syndrome in children (MIS-C; also called the pediatric inflammatory multisystem syndrome); Levin 3 provides commentary.To address the burden of MIS-C in France, a nationwide... |
4795 | 2 | and Dufort et al., these results showed a median patient age of 8 years, a temporospatial distribution that is evocative of a link to the outbreak of coronavirus disease 2019 , and an overlap of macrophage activation syndrome, serositis, Kawasaki's disease-like features, and myocarditis in half the cases.4 As of June 2... |
4747 | 1 | Title: Low HDL and high triglycerides predict COVID-19 severity. Abstract: Abstract Lipids are indispensable in the SARS-CoV-2 infection process. The clinical significance of plasma lipid profile during COVID-19 has not been rigorously evaluated. We aim to ascertain the association of the plasma lipid profile with SARS... |
4747 | 2 | The presence of atherogenic dyslipidaemia during the infection was strongly and independently associated with a worse COVID-19 infection prognosis. The low HDL cholesterol and high triglyceride concentrations measured before or during hospitalization are strong predictors of a severe course of the disease. The lipid pr... |
9366 | 0 | Title: David Oliver: “Considerably transformed”—changing the narrative on admitting older patients. Abstract: Considerably transformed"-changing the narrative on admitting older patients. |
5334 | 1 | Title: SARS-CoV-2 spike ectodomain targets α7 nicotinic acetylcholine receptors. Abstract: Virus entry into animal cells is initiated by attachment to target macromolecules located on host cells. The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) trimeric spike glycoprotein targets host angiotensin conver... |
5334 | 2 | Importantly, SCoV2P potentiates and inhibits ACh-induced α7 nAChR responses by an allosteric mechanism, with nicotine enhancing these effects. Live-cell confocal microscopy was used to confirm that SCoV2P interacts with α7 nAChRs in transfected neuronal-like N2a and human embryonic kidney 293 cells. The SARS-CoV-2 ecto... |
6652 | 1 | Title: The omicron (B.1.1.529) SARS-CoV-2 variant of concern does not readily infect Syrian hamsters. Abstract: Abstract The emergence of SARS-CoV-2 variants of concern (VoCs) has exacerbated the COVID-19 pandemic. End of November 2021, a new SARS-CoV-2 variant namely the omicron (B.1.1.529) emerged. Since this omicron... |
6652 | 2 | Moreover, histopathological examination of the lungs from omicron-infecetd hamsters revealed no signs of peri-bronchial inflammation or bronchopneumonia. Further experiments are needed to determine whether the omicron VoC replicates possibly more efficiently in the upper respiratory tract of hamsters than in their lung... |
9032 | 1 | Title: SARS-CoV-2 Vaccination and Protection Against Clinical Disease: A Retrospective Study, Bouches-du-Rhône District, Southern France, 2021. Abstract: From January 18th to August 13th, 2021, 13,804 unvaccinated and 1,156 patients who had received at least one COVID-19 vaccine dose were tested qPCR-positive for SARS-... |
9032 | 2 | SARS-CoV-2 infection was significantly more likely to occur in the first 13 days post-vaccine injection in those who received a single dose (48.9%) than two doses (27.4%, p< 10-3). Among 161 patients considered as fully vaccinated, i.e., >14 days after the completion of the vaccinal scheme (one dose for Johnson and Joh... |
9032 | 3 | Compared to partial vaccination, complete vaccination provided an even stronger protective effect, confirming effectiveness to prevent severe forms of COVID-19.. |
580 | 1 | Title: A Meta-Analysis of the Impacts of Genetically Modified Crops. Abstract: Background Despite the rapid adoption of genetically modified (GM) crops by farmers in many countries, controversies about this technology continue. Uncertainty about GM crop impacts is one reason for widespread public suspicion. Objective W... |
580 | 2 | Yield and profit gains are higher in developing countries than in developed countries. Limitations Several of the original studies did not report sample sizes and measures of variance. Conclusion The meta-analysis reveals robust evidence of GM crop benefits for farmers in developed and developing countries. Such eviden... |
9491 | 0 | Title: Change in Antibodies to SARS-CoV-2 Over 60 Days Among Health Care Personnel in Nashville, Tennessee. Abstract: Hui Zeng, MD; Chen Xu, BS; Junli Fan, MD; Yueting Tang, PhD; Qiaoling Deng, MD; Wei Zhang, MD, PhD; Xinghua Long, MD, PhD. |
6526 | 1 | Title: Association of Logic’s hip hop song “1-800-273-8255” with Lifeline calls and suicides in the United States: interrupted time series analysis. Abstract: Abstract Objective To assess changes in daily call volumes to the US National Suicide Prevention Lifeline and in suicides during periods of wide scale public att... |
6526 | 2 | Results In the 34 day period after the three events with the strongest public attention (the song’s release, the MTV Video Music Awards 2017, and Grammy Awards 2018), Lifeline received an excess of 9915 calls (95% confidence interval 6594 to 13 236), an increase of 6.9% (95% confidence interval 4.6% to 9.2%, P<0.001) o... |
4346 | 0 | Title: Skill utilization at work: Opportunity and motivation. Abstract: Technological choices, product market strategies, and other organizational characteristics affect how tasks are grouped into jobs.The design of jobs determines the skills needed by workers in order to do them effectively.However, people possess ski... |
4974 | 0 | Title: COVID-19 – exploring the implications of long-term condition type and extent of multimorbidity on years of life lost: a modelling study. Abstract: The COVID-19 pandemic is responsible for increasing deaths globally. Most estimates have focused on numbers of deaths, with little direct quantification of years of l... |
7913 | 0 | Title: Global food system emissions could preclude achieving the 1.5° and 2°C climate change targets. Abstract: The Paris Agreement's goal of limiting the increase in global temperature to 1.5° or 2°C above preindustrial levels requires rapid reductions in greenhouse gas emissions. Although reducing emissions from foss... |
5611 | 1 | Title: Time is of the essence: containment of the SARS-CoV-2 epidemic in Switzerland from February to May 2020. Abstract: ABSTRACT AIM In late February and early March 2020, Switzerland experienced rapid growth of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infections with 30,243 confirmed cases and 1,... |
5611 | 2 | RESULTS We estimated the basic reproduction number R 0 = 2.61 (95% compatibility interval, CI: 2.51–2.71) during the early exponential phase of the SARS-CoV-2 epidemic in Switzerland. After the implementation of NPIs, the effective reproduction number approached R e = 0.64 (95% CI: 0.61–0.66). Based on the observed dou... |
5611 | 3 | CONCLUSIONS The introduction of NPIs in March 2020 prevented thousands of SARS-CoV-2-related deaths in Switzerland. Early implementation of NPIs during SARS-CoV-2 outbreaks can reduce the number of deaths and the necessary duration of strict control measures considerably.. |
8480 | 1 | Title: Comment devenir docteur en sociologie sans posséder le métier de sociologue ?1. Abstract: Peut-on devenir docteur en sociologie sans avoir acquis les compétences constitutives du métier de sociologue ? Une telle interrogation peut paraître provocatrice. Or, l'examen rigoureux et détaillé d'une thèse soutenue le ... |
8480 | 2 | Mais le jugement sur ce cas précis fait apparaître, en conclusion, l'urgence qu'il y a à engager une réflexion collective sur les conditions d'entrée dans le métier de sociologue.. |
6625 | 1 | Title: Temporal maturation of neutralizing antibodies in COVID-19 convalescent individuals improves potency and breadth to circulating SARS-CoV-2 variants. Abstract: Antibody titers against SARS-CoV-2 slowly wane over time. Here, we examined how time affects antibody potency. To assess the impact of antibody maturation... |
6625 | 2 | Thus, maturation of the antibody response to SARS-CoV-2 potentiates cross-neutralizing ability to circulating variants, suggesting that declining antibody titers may not be indicative of declining protection.. |
5615 | 0 | Title: Pulmonary embolism, part I: Epidemiology, risk factors and risk stratification, pathophysiology, clinical presentation, diagnosis and nonthrombotic pulmonary embolism.. Abstract: Pulmonary embolism is an important clinical entity with considerable mortality despite advances in diagnosis and treatment. In the pre... |
5602 | 1 | Title: Chloroquine-Induced First-Episode Psychosis in a Patient Self-medicated for COVID-19. Abstract: Hydroxychloroquine is one of the most promising therapies tested in patients with COVID-19, despite worldwide controversies (1Fihn S.D. Perencevich E. Bradley S.M. Caution needed on the use of chloroquine and hydroxyc... |
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