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Instruct: Given a scientific claim, retrieve documents that support or refute the claim Query: The effect of Lipopolysaccharides on kidney barrier function is dependent on inflammation levels.
[ { "docid": "16355392", "title": "Modification of kidney barrier function by the urokinase receptor", "text": "Podocyte dysfunction, represented by foot process effacement and proteinuria, is often the starting point for progressive kidney disease. Therapies aimed at the cellular level of the disease are...
[ { "docid": "16999023", "title": "Cell Stem Cell Article In Vivo Fate Analysis Reveals the Multipotent and Self-Renewal Capacities of Sox2 + Neural Stem Cells in the Adult Hippocampus", "text": "To characterize the properties of adult neural stem cells (NSCs), we generated and analyzed Sox2-GFP transgeni...
500
Instruct: Given a scientific claim, retrieve documents that support or refute the claim Query: Headaches are correlated with cognitive impairment.
[ { "docid": "17930286", "title": "Headache, migraine, and structural brain lesions and function: population based Epidemiology of Vascular Ageing-MRI study", "text": "OBJECTIVE To evaluate the association of overall and specific headaches with volume of white matter hyperintensities, brain infarcts, and ...
[ { "docid": "26231129", "title": "A framework for understanding and targeting residual disease in oncogene-driven solid cancers", "text": "Molecular targeted therapy has the potential to dramatically improve survival in patients with cancer. However, complete and durable responses to targeted therapy are...
383
Instruct: Given a scientific claim, retrieve documents that support or refute the claim Query: Epidemiological disease burden from noncommunicable diseases is more prevalent in high economic settings.
[ { "docid": "13770184", "title": "Global, regional, and national comparative risk assessment of 79 behavioural, environmental and occupational, and metabolic risks or clusters of risks, 1990–2015: a systematic analysis for the Global Burden of Disease Study 2015", "text": "BACKGROUND The Global Burden of...
[ { "docid": "26231129", "title": "A framework for understanding and targeting residual disease in oncogene-driven solid cancers", "text": "Molecular targeted therapy has the potential to dramatically improve survival in patients with cancer. However, complete and durable responses to targeted therapy are...
588
Instruct: Given a scientific claim, retrieve documents that support or refute the claim Query: In transgenic mice harboring green florescent protein under the control of the Sox2 promoter, more than 50 percent of the cells with green florescent colocalize with cell proliferation markers.
[ { "docid": "16999023", "title": "Cell Stem Cell Article In Vivo Fate Analysis Reveals the Multipotent and Self-Renewal Capacities of Sox2 + Neural Stem Cells in the Adult Hippocampus", "text": "To characterize the properties of adult neural stem cells (NSCs), we generated and analyzed Sox2-GFP transgeni...
[ { "docid": "26231129", "title": "A framework for understanding and targeting residual disease in oncogene-driven solid cancers", "text": "Molecular targeted therapy has the potential to dramatically improve survival in patients with cancer. However, complete and durable responses to targeted therapy are...
938
Instruct: Given a scientific claim, retrieve documents that support or refute the claim Query: Persister cells provide relapse resistance in cancer patients.
[ { "docid": "26231129", "title": "A framework for understanding and targeting residual disease in oncogene-driven solid cancers", "text": "Molecular targeted therapy has the potential to dramatically improve survival in patients with cancer. However, complete and durable responses to targeted therapy are...
[ { "docid": "16472469", "title": "Targeting BRCA1 and BRCA2 Deficiencies with G-Quadruplex-Interacting Compounds", "text": "G-quadruplex (G4)-forming genomic sequences, including telomeres, represent natural replication fork barriers. Stalled replication forks can be stabilized and restarted by homologou...
1391
Instruct: Given a scientific claim, retrieve documents that support or refute the claim Query: miR-142-5P is a known regulator of raised body temperature.
[ { "docid": "6766459", "title": "RBM3 regulates temperature sensitive miR-142–5p and miR-143 (thermomiRs), which target immune genes and control fever", "text": "Fever is commonly used to diagnose disease and is consistently associated with increased mortality in critically ill patients. However, the mol...
[ { "docid": "5884524", "title": "Impact of diabetes on long-term prognosis in patients with unstable angina and non-Q-wave myocardial infarction: results of the OASIS (Organization to Assess Strategies for Ischemic Syndromes) Registry.", "text": "BACKGROUND Although unstable coronary artery disease is th...
342
Instruct: Given a scientific claim, retrieve documents that support or refute the claim Query: Diabetic patients with acute coronary syndrome experience decreased short-term and long-term risk for bleeding events.
[ { "docid": "7873737", "title": "Platelet glycoprotein IIb/IIIa inhibitors reduce mortality in diabetic patients with non-ST-segment-elevation acute coronary syndromes.", "text": "BACKGROUND Diabetes mellitus is a major risk factor for adverse outcomes after acute coronary syndromes (ACS). Because this d...
[ { "docid": "13770184", "title": "Global, regional, and national comparative risk assessment of 79 behavioural, environmental and occupational, and metabolic risks or clusters of risks, 1990–2015: a systematic analysis for the Global Burden of Disease Study 2015", "text": "BACKGROUND The Global Burden of...
418
Instruct: Given a scientific claim, retrieve documents that support or refute the claim Query: Fibroblast Growth Factor is a ligand which signals through receptor tyrosine kinases.
[ { "docid": "16660256", "title": "Sprouty1 Regulates Reversible Quiescence of a Self-Renewing Adult Muscle Stem Cell Pool during Regeneration", "text": "Satellite cells are skeletal muscle stem cells capable of self-renewal and differentiation after transplantation, but whether they contribute to endogen...
[ { "docid": "16472469", "title": "Targeting BRCA1 and BRCA2 Deficiencies with G-Quadruplex-Interacting Compounds", "text": "G-quadruplex (G4)-forming genomic sequences, including telomeres, represent natural replication fork barriers. Stalled replication forks can be stabilized and restarted by homologou...
772
Instruct: Given a scientific claim, retrieve documents that support or refute the claim Query: Mice are incapable of producing neutralizing antibodies in reponse to the Chikungunya virus (CHIKV) produced in mosquitos.
[ { "docid": "24922825", "title": "A chikungunya fever vaccine utilizing an insect-specific virus platform", "text": "Traditionally, vaccine development involves tradeoffs between immunogenicity and safety. Live-attenuated vaccines typically offer rapid and durable immunity but have reduced safety when co...
[ { "docid": "16355392", "title": "Modification of kidney barrier function by the urokinase receptor", "text": "Podocyte dysfunction, represented by foot process effacement and proteinuria, is often the starting point for progressive kidney disease. Therapies aimed at the cellular level of the disease are...
997
"Instruct: Given a scientific claim, retrieve documents that support or refute the claim\nQuery: Pyr(...TRUNCATED)
[{"docid":"16472469","title":"Targeting BRCA1 and BRCA2 Deficiencies with G-Quadruplex-Interacting C(...TRUNCATED)
[{"docid":"26231129","title":"A framework for understanding and targeting residual disease in oncoge(...TRUNCATED)
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