query_id stringclasses 10
values | query stringclasses 10
values | positive_passages listlengths 1 4 | negative_passages listlengths 30 30 | __index_level_0__ int64 60 764 |
|---|---|---|---|---|
1255 | The proliferative capacity of progenitors is regulated cell-autonomously. | [
{
"docid": "16939583",
"text": "Variation in cerebral cortex size and complexity is thought to contribute to differences in cognitive ability between humans and other animals. Here we compare cortical progenitor cell output in humans and three nonhuman primates using directed differentiation of pluripotent ... | [
{
"docid": "3495456",
"text": "Summary Neutrophils are specialized innate cells that require constant replenishment from proliferative bone marrow (BM) precursors as a result of their short half‐life. Although it is established that neutrophils are derived from the granulocyte‐macrophage progenitor (GMP), t... | 722 |
973 | Primary cervical cytology screening with HPV detection has higher longitudinal sensitivity to detect severe cervical intraepithelial neoplasia than conventional cytology. | [
{
"docid": "27446873",
"text": "OBJECTIVE To assess the performance and impact of primary human papillomavirus (HPV) DNA screening with cytology triage compared with conventional cytology on cervical cancer and severe pre-cancerous lesions. DESIGN Randomised trial. SETTING Population based screening program... | [
{
"docid": "6561200",
"text": "BACKGROUND Primary cervical screening with both human papillomavirus (HPV) DNA testing and cytological examination of cervical cells with a Pap test (cytology) has been evaluated in randomized clinical trials. Because the vast majority of women with positive cytology are also ... | 559 |
746 | MafA phosphorylation enhances its ubiquitination. | [
{
"docid": "11291348",
"text": "The Maf oncoproteins are b-Zip transcription factors of the AP-1 superfamily. They are involved in developmental, metabolic, and tumorigenic processes. Maf proteins are overexpressed in about 50% of human multiple myelomas. Here, we show that Maf-transforming activity is cont... | [
{
"docid": "21307488",
"text": "HER-2/neu amplification or overexpression can make cancer cells resistant to apoptosis and promotes their growth. p53 is crucial in regulating cell growth and apoptosis, and is often mutated or deleted in many types of tumour. Moreover, many tumours with a wild-type gene for ... | 430 |
1098 | Stacking is more stable when a purine is present in the +5 position (C1698). | [{"docid":"13552682","text":"In eukaryotes, accurate protein synthesis relies on a family of transla(...TRUNCATED) | [{"docid":"410286","text":"The Agrobacterium vacuum infiltration method has made it possible to tran(...TRUNCATED) | 634 |
790 | Microglia are an innate immune cell type of the peripheral nervous system. | [{"docid":"15493354","text":"Recent findings challenge the concept that microglia solely function in(...TRUNCATED) | [{"docid":"17438862","text":"Postmortem immunohistochemical studies have revealed a state of chronic(...TRUNCATED) | 459 |
1164 | The G34R/V mutation creates a hypomethylated phenotype at the H3K36 histone. | [{"docid":"4455466","text":"Recognition of modified histones by ‘reader’ proteins plays a critic(...TRUNCATED) | [{"docid":"4312169","text":"Glioblastoma multiforme (GBM) is a lethal brain tumour in adults and chi(...TRUNCATED) | 669 |
1305 | Tirasemtiv targets fast-twitch muscle. | [{"docid":"12631697","text":"Limited neural input results in muscle weakness in neuromuscular diseas(...TRUNCATED) | [{"docid":"40631095","text":"Increased dyspnea and reduced exercise capacity in pulmonary arterial h(...TRUNCATED) | 744 |
1340 | "Ultrasound guidance significantly reduces the number of needle insertion attempts necessary for a g(...TRUNCATED) | [{"docid":"15482274","text":"OBJECTIVE To determine whether ultrasound imaging can reduce the risk o(...TRUNCATED) | [{"docid":"52874170","text":"CONTEXT Diagnostic lumbar punctures (LPs), commonly used to rule out me(...TRUNCATED) | 764 |
90 | Adult tissue-resident macrophages stem from the embryonal yolk sac and fetal liver. | [{"docid":"22406695","text":"Macrophages are distributed in tissues throughout the body and contribu(...TRUNCATED) | [{"docid":"4254064","text":"DEFINITIVE erythropoiesis in birds originates from stem cells that emerg(...TRUNCATED) | 60 |
1034 | "Removal of H3K9me3 by ectopic expression of other H3K9 demethylases decreases reprogramming efficie(...TRUNCATED) | [{"docid":"4547102","text":"Aberrant epigenetic reprogramming often results in developmental defects(...TRUNCATED) | [{"docid":"15803282","text":"The extremely low efficiency of human embryonic stem cell (hESC) deriva(...TRUNCATED) | 597 |
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