query_id stringclasses 10
values | query stringclasses 10
values | positive_passages listlengths 1 3 | negative_passages listlengths 30 30 | __index_level_0__ int64 67 746 |
|---|---|---|---|---|
930 | Patients with panic anxiety show decreased CSF levels of hypocretin. | [
{
"docid": "16056514",
"text": "Panic disorder is a severe anxiety disorder with recurrent, debilitating panic attacks. In individuals with panic disorder there is evidence of decreased central gamma-aminobutyric acid (GABA) activity as well as marked increases in autonomic and respiratory responses after i... | [
{
"docid": "44830890",
"text": "OBJECTIVE To investigate the frequency of depressive and anxiety disorders in patients with chronic daily headache. BACKGROUND There is a lack of data in the literature on the extent of psychiatric comorbidity in patients with different subtypes of chronic daily headache. MET... | 533 |
104 | Allogeneic mechanical circulatory support is not as effective as autologous mechanical circulatory support for treating acute myocardial infarction. | [
{
"docid": "40164383",
"text": "CONTEXT Mesenchymal stem cells (MSCs) are under evaluation as a therapy for ischemic cardiomyopathy (ICM). Both autologous and allogeneic MSC therapies are possible; however, their safety and efficacy have not been compared. OBJECTIVE To test whether allogeneic MSCs are as sa... | [
{
"docid": "24097933",
"text": "Paraquat poisoning is characterized by multiorgan failure and pulmonary fibrosis with respiratory failure. Multiorgan failure with circulatory collapse is a major cause of early death within 3 days of paraquat ingestion. Recent studies suggested that continuous venovenous hem... | 67 |
472 | Glucose restriction to 0.05% reduces RLS (replicative life span) by 20-40% in S. cerevisiae. | [
{
"docid": "4414481",
"text": "Calorie restriction (CR) extends lifespan in a wide spectrum of organisms and is the only regimen known to lengthen the lifespan of mammals. We established a model of CR in budding yeast Saccharomyces cerevisiae. In this system, lifespan can be extended by limiting glucose or ... | [
{
"docid": "1754001",
"text": "The sirtuins are a phylogenetically conserved family of NAD(+) -dependent protein deacetylases that consume one molecule of NAD(+) for every deacetylated lysine side chain. Their requirement for NAD(+) potentially makes them prone to regulation by fluctuations in NAD(+) or bio... | 275 |
382 | "Environmentally-induced senescence is mimicked in disease modeling by adding specific molecules to (...TRUNCATED) | [{"docid":"11659421","text":"Reprogramming somatic cells to induced pluripotent stem cells (iPSCs) r(...TRUNCATED) | [{"docid":"4709641","text":"Efforts to develop drugs for Alzheimer's disease (AD) have shown promise(...TRUNCATED) | 226 |
425 | "For every 1,000 children with cerebral palsy, more than 300 of them are premature or underweight at(...TRUNCATED) | [{"docid":"33257464","text":"CONTEXT Although cerebral palsy (CP) among extremely premature infants (...TRUNCATED) | [{"docid":"20645335","text":"OBJECTIVE To systematically review and integrate data on the neurodevel(...TRUNCATED) | 251 |
315 | Decrease of p62 in prostate tumor stroma results in defective autophagy. | [{"docid":"3701541","text":"Hepatic stellate cells (HSCs) play critical roles in liver fibrosis and (...TRUNCATED) | [{"docid":"26735905","text":"The tumor microenvironment plays a critical role in cancer progression,(...TRUNCATED) | 181 |
1115 | "Surgical treatment is not superior to non-surgical in treating adults with displaced fractures of t(...TRUNCATED) | [{"docid":"44048701","text":"IMPORTANCE The need for surgery for the majority of patients with displ(...TRUNCATED) | [{"docid":"19182166","text":"BACKGROUND The aim of the study was to report the 2-year outcome after (...TRUNCATED) | 644 |
434 | "Foxp3 enables the expression of transcriptional regulators implicated in memory T cell development.(...TRUNCATED) | [{"docid":"9500590","text":"Regulatory T (Treg) cells, whose differentiation and function are contro(...TRUNCATED) | [{"docid":"41877386","text":"CD4(+)CD25(+) regulatory T cells (T regs) play a major role in the main(...TRUNCATED) | 257 |
1293 | There is no increased risk of hypospadias with clomiphene. | [{"docid":"43329366","text":"Clomifene is widely used for inducing ovulation.1 It is structurally re(...TRUNCATED) | [{"docid":"380526","text":"Hypospadias is a common congenital malformation of the male external geni(...TRUNCATED) | 737 |
1307 | Tonic signaling from the scFv induces constitutive stimulation. | [{"docid":"18231807","text":"Chimeric antigen receptors (CARs) targeting CD19 have mediated dramatic(...TRUNCATED) | [{"docid":"34016944","text":"PURPOSE Tyrosine kinase (TK) inhibitors are emerging as a promising new(...TRUNCATED) | 746 |
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