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73
Activator-inhibitor pairs are provided ventrally by Xrl-sizzled.
[ { "docid": "6076903", "text": "Embryos have the ability to self-regulate and regenerate normal structures after being sectioned in half. How is such a morphogenetic field established? We discovered that quadruple knockdown of ADMP and BMP2/4/7 in Xenopus embryos eliminates self-regulation, causing ubiquitou...
[ { "docid": "1031534", "text": "Spemann's organizer plays a key role in dorsal-ventral (DV) patterning in the amphibian embryo by secreting diffusible proteins such as Chordin, an antagonist to ventralizing bone morphogenetic proteins (BMPs). The DV patterning is so robust that an amphibian embryo with its v...
47
1055
Risk-adjusted mortality rates are similar in teaching and non-teaching hospitals.
[ { "docid": "13906581", "text": "Background Extensive debate exists in the healthcare community over whether outcomes of medical care at teaching hospitals and other healthcare units are better or worse than those at the respective nonteaching ones. Thus, our goal was to systematically evaluate the evidence...
[ { "docid": "20746604", "text": "OBJECTIVE To examine the association between the use of right heart catheterization (RHC) during the first 24 hours of care in the intensive care unit (ICU) and subsequent survival, length of stay, intensity of care, and cost of care. DESIGN Prospective cohort study. SETTING ...
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672
L3MBTL2 binds to H2AK119Ub marked chromatin to form a PRC1 complex.
[ { "docid": "15635366", "text": "L3mbtl2 has been implicated in transcriptional repression and chromatin compaction but its biological function has not been defined. Here we show that disruption of L3mbtl2 results in embryonic lethality with failure of gastrulation. This correlates with compromised prolifera...
[ { "docid": "1791637", "text": "In embryonic stem (ES) cells, bivalent chromatin domains with overlapping repressive (H3 lysine 27 tri-methylation) and activating (H3 lysine 4 tri-methylation) histone modifications mark the promoters of more than 2,000 genes. To gain insight into the structure and function o...
393
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"Mice defective for deoxyribonucleic acid (DNA) polymerase m (polm) reveal increased sensitivity to (...TRUNCATED)
[{"docid":"32275758","text":"DNA polymerases mu (pol mu), lambda (pol lambda), and terminal deoxynuc(...TRUNCATED)
[{"docid":"11569583","text":"DNA polymerase β (Pol β) is an error-prone enzyme which has been foun(...TRUNCATED)
451
69
Activation of PPM1D enhances p53 function.
[{"docid":"4414547","text":"Improved sequencing technologies offer unprecedented opportunities for i(...TRUNCATED)
[{"docid":"23985464","text":"Wild-type p53 has recently been shown to repress transcription from sev(...TRUNCATED)
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225
"Cancer-associated fibroblasts (CAFs) have no known interaction with cancer cells in the formation a(...TRUNCATED)
[{"docid":"6944800","text":"Cancers develop in complex tissue environments, which they depend on for(...TRUNCATED)
[{"docid":"3727986","text":"Cancer-associated fibroblasts (CAFs) promote tumour invasion and metasta(...TRUNCATED)
132
1106
"Students who perform poorly in the early years of medical school are less likely to commit professi(...TRUNCATED)
[{"docid":"6710713","text":"OBJECTIVE To determine whether there are risk factors in a doctor's time(...TRUNCATED)
[{"docid":"17374970","text":"AIM To determine attrition and predictors of academic success among med(...TRUNCATED)
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389
Ethanol stress increases the expression of IBP in bacteria.
[{"docid":"1148122","text":"Understanding the genetic basis of adaptation is a central problem in bi(...TRUNCATED)
[{"docid":"21602220","text":"The physiology of ethanologenic Escherichia coli grown anaerobically in(...TRUNCATED)
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155
BCL-2 activation antagonizes the apoptotic effects of c-Myc.
[{"docid":"37549932","text":"Resistance to apoptosis, often achieved by the overexpression of antiap(...TRUNCATED)
[{"docid":"34439544","text":"The BCL-2 (B cell CLL/Lymphoma) family is comprised of approximately tw(...TRUNCATED)
90
165
Bariatric surgery increases rates of postmenopausal breast cancer.
[{"docid":"5824985","text":"BACKGROUND Bariatric surgery is becoming a more widespread treatment for(...TRUNCATED)
[{"docid":"18872233","text":"IMPORTANCE Bariatric surgery is associated with sustained weight loss a(...TRUNCATED)
97
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