inputs
stringlengths 181
12.5k
| targets
stringlengths 7
220
| _template_idx
int64 0
9
| _task_source
stringclasses 1
value | _task_name
stringclasses 1
value | _template_type
stringclasses 2
values |
|---|---|---|---|---|---|
Given a context passage, generate a question from the passage such that its answer is shortest continous span from the passage.
One example: In 1582 the united provinces invited francis, duke of anjou to lead them; but after a failed attempt to take antwerp in 1583, the duke left the netherlands again. after the assassination of william of orange (10 july 1584), both henry iii of france and elizabeth i of england declined the offer of sovereignty. however, the latter agreed to turn the united provinces into a protectorate of england (treaty of nonsuch, 1585), and sent the earl of leicester as governor-general. this was unsuccessful and in 1588 the provinces became a confederacy. the union of utrecht is regarded as the foundation of the republic of the seven united provinces, which was not recognized by the spanish empire until the peace of westphalia in 1648.
Solution is here: In what year did francis, duke of anjou leave the netherlands?
Explanation: The generated question is perfect. Because the question is based on second sentence of the input passage and its answer is 1583.
Now, solve this: The Conquest of Melilla occurred in September 1497, when a fleet sent by the Duke of Medina Sidonia seized the north African city of Melilla., as continuation of Reconquest of Mauritania Tingitana During the 15th century the mediterranean cities of the Sultanate of Fez fell in decadence in opposition to cities located in the Atlantic facade, which concentrated most of the economic activity. By the end of the 15th century, the port of Melilla, that had been often disputed between the rulers of Fez and Tlemcen, was nearly abandoned. Plans for the conquest occurred as soon as the Fall of Granada in 1492. Spanish captains Lezcano and Lorenzo Zafra visited the coast of Northern Africa to identify possible locations for the Spanish to overtake, and Melilla was identified as a prime candidate. Melilla was, however, in the Portuguese zone of influence under the terms of the 1479 Treaty of Alcacovaz. At Tordesillas in 1494, King John II of Portugal, the Portuguese ruler agreed to make an exception and permitted the Spanish to attempt the conquest of Melilla. The duke sent Pedro Estopinan who conquered the city virtually without a fight in 1497, as internal conflicts had depleted it of troops, and its defenses were weakened. The Wattasid ruler Muhammad al-Shaykh sent a detachment of cavalrymen to retake control of the city, but they were repulsed by the guns of the Spanish ships.
Solution:
|
What happened second: The Conquest of Melilla or Treaty of Alcáçovaz?
| 6
|
NIv2
|
task470_mrqa_question_generation
|
fs_opt
|
instruction:
Given a context passage, generate a question from the passage such that its answer is shortest continous span from the passage.
question:
James Dargaville (born 25 April 1992) is an Australian rugby union footballer who currently plays as a wing for the Brumbies in Super Rugby.
answer:
What is the position James Dargaville plays in football?
question:
Electronic book publishing has many of the same risks and opportunities as electronic music publishing. By delivering text direct to the user's computer screen, the e-book could cut down costs, and allow creators to deal directly with their audience, bypassing traditional publishers and readers. But it also raises the possibility of mass piracy . Phil Rance, founder and managing director of Online Originals, a London-based e-book publisher, sums it up. "No one wants Napster to happen to books." Indeed, the most popular MP3 have put the frighteners on an industry that generally operates some way behind the "bleeding edge". The Mata Group, a leading US-based market researcher, says publishers are far too concerned about protecting their rights, "We believe all the recent legal control over Napster is like putting a finger in a river that is already overflowing. Publishers need to deal with reality and come up with new ways to develop wide electronic distribution , asking the question: 'How can we use the certainty of wide distribution to our advantage?'" At the moment, most publishers would like to limit the use of e-books to the person who bought them, or to the computer used to download them. If that can be done, e-books become just an extra income stream in a publishing industry that would continue to operate the way it does today, according to Terry Robinson, business manager for Adobe's e-paper group. "If you've cracked digital rights aspect, you've cracked the market," he says. Robert Nichols, Books Director at BOL agrees, "Rights management is absolutely important. Publishers just say that 'until copyright is secure, we're not going to talk'."
answer:
What do publishers care most about e-books?
question:
This was a 12-week randomized, placebo-controlled trial to assess the efficacy of quetiapine monotherapy in the treatment of posttraumatic stress disorder (PTSD). Eighty patients were randomly assigned to treatment with either quetiapine or placebo. The primary outcome measure was the Clinician-Administered PTSD Scale (CAPS). Secondary efficacy measures included the CAPS subscales, the Davidson Trauma Scale, the Positive and Negative Syndrome Scale (PANSS), the Clinical Global Impressions (CGI) scales for severity of Illness and improvement, the Hamilton Depression Rating Scale (HAM-D), and the Hamilton Anxiety Rating Scale (HAM-A). Safety measurements included adverse events, vital signs, the Abnormal Involuntary Movement Scale, the Barnes Akathisia Scale, the Simpson-Angus Scale, and the Arizona Sexual Experiences Scale. After a 1-week placebo run-in, quetiapine was started at a daily dosage of 25 mg and increased to a maximum of 800 mg; the average was 258 mg (range, 50-800 mg). Reductions in CAPS total, re-experiencing, and hyperarousal scores were significantly greater for the quetiapine group than for the placebo group. Greater improvements were also observed for quetiapine in scores on the Davidson Trauma Scale, CGI severity and improvement ratings, PANSS positive symptom and general psychopathology subscales, HAM-A, and HAM-D than for placebo. Adverse events were generally mild and expected based on prior studies of quetiapine in this and other patient population. There were no differences in safety measures between groups. Quetiapine monotherapy was efficacious in the treatment of PTSD. These findings suggest quetiapine as a single agent is effective in treating military PTSD.
answer:
|
Symptoms of which disorder are evaluated with the Davidson Trauma Scale?
| 9
|
NIv2
|
task470_mrqa_question_generation
|
fs_opt
|
Given a context passage, generate a question from the passage such that its answer is shortest continous span from the passage.
[Q]: The Linth (pronounced (lnt) ''lint'') is a Swiss river that rises near the village of Linthal in the mountains of the canton of Glarus, and eventually flows into the Obersee section of Lake Zurich.
[A]: What river does Linth turn into?
[Q]: Miguel Angel Garcia Tebar (born 26 September 1979), known as Miguel Garcia, is a Spanish retired footballer who played as a defensive midfielder.
[A]: What role does Miguel Ángel García Tébar play in football?
[Q]: Albino Perez (died 8 August 1837) was a Mexican soldier and politician who was appointed Governor of New Mexico.
[A]:
|
Which was the position that Albino Pérez held?
| 5
|
NIv2
|
task470_mrqa_question_generation
|
fs_opt
|
Given a context passage, generate a question from the passage such that its answer is shortest continous span from the passage.
[Q]: Sr-Vagsy is a former municipality in Sogn og Fjordane county in Norway.
[A]: In which country would you find Sør-Vågsøy?
[Q]: Today, the Eiffel Tower, which serves an important role in television and radio broadcasts, is considered an architectural wonder. It attracts more visitors than any other paid tourist attraction in the world. The Eiffel Tower was designed by the French engineer and bridge builder Alexandre Gustave Eiffel for the Paris Exposition of 1889. The tower is 300 m high and consists of an open iron framework making it the highest manmade structure in the world at the time. It was almost not built. After being awarded the contract to build the tower, Eiffel discovered that the Exposition Committee would only provide about a quarter of the money needed to construct it. Eiffel himself would have to finance the balance. He thought of a deal that would make him a very rich man. He agreed to independently find the people to fund his tower but he wanted to be the only one to control of the tower and he wanted the profits for twenty years. They agreed. To everyone's surprise, including Eiffel, the tower was paid off in the first year. The deal that Eiffel came up with was probably what saved the tower from destruction. A Committee of Three Hundred was formed and they demanded an end to its building. Many members of the committee said, "They have only put up the framework of this monument, It has no skin." Many sculptors and architects protested , in the name of threatened French art and history, about the useless Eiffel Tower, in the heart of their capital. It is built of iron, which is an inferior material, and a single beam of it is unable to support large stresses. That is why the tower appears over-engineered by today's standards. Though, from this very weakness, its simple beauty can be found. If you look at the tower, the structure of it sort of copies the biological cellular structure of a plant.
[A]: What was the Eiffel Tower originally designed for?
[Q]: Arrhythmogenic right ventricular cardiomyopathy (ARVC) is an autosomal dominant heart muscle disorder that causes arrhythmia, heart failure, and sudden death. Previously we mapped the genetic locus for the triad of autosomal recessive ARVC, palmoplantar keratoderma, and woolly hair (Naxos disease) to chromosome 17q21, in which the gene for plakoglobin is encoded. This protein is a key component of desmosomes and adherens junctions, and is important for the tight adhesion of many cell types, including those in the heart and skin. We studied 19 individuals with Naxos disease, as well as unaffected family members and unrelated individuals from the neighbouring Greek islands of Naxos and Milos. Gene sequence was determined by reverse transcriptase PCR from RNA isolated from the skin of an affected individual and mutations in other cases were confirmed by restriction-enzyme analysis. A homozygous 2 base pair deletion in the plakoglobin gene was identified only in the 19 affected individuals. This deletion caused a frameshift and premature termination of the protein, which was shown by western blot analysis. 29 clinically unaffected family members were heterozygous for the mutation; 20 unrelated individuals from Naxos and 43 autosomal dominant ARVC probands were homozygous for the normal allele. The finding of a deletion in plakoglobin in ARVC suggests that the proteins involved in cell-cell adhesion play an important part in maintaining myocyte integrity, and when junctions are disrupted, cell death, and fibrofatty replacement occur. Therefore, the discovery of a mutation in a protein with functions in maintaining cell junction integrity has important implications for other dominant forms of ARVC, related cardiomyopathies, and other cutaneous diseases.
[A]:
|
Which gene is mutated in a subtype of arrhythmogenic right ventricular cardiomyopathy known as Naxos disease?
| 5
|
NIv2
|
task470_mrqa_question_generation
|
fs_opt
|
Given a context passage, generate a question from the passage such that its answer is shortest continous span from the passage.
Ex Input:
FK506 binding protein 6, also known as FKBP6, is a human gene.
Ex Output:
In what living being can FKBP6 be found?
Ex Input:
In anaesthesia and in the intensive care unit, benzodiazepines have proven safe and effective agents for the induction and maintenance of sedation for a variety of therapeutic goals. However, in these contexts, or in benzodiazepine overdose, it is often desirable to be able to terminate or interrupt sedation without waiting for the effect of the benzodiazepine to become dissipated by normal metabolism and excretion. Flumazenil, a 1,4-imidazobenzodiazepine, is a highly effective, specific benzodiazepine antagonist which is indicated for use when the effect of a benzodiazepine must be attenuated or terminated at short notice. It acts by displacing other benzodiazepines from the receptor site by competitive inhibition. The onset of effect after intravenous administration occurs within 1 to 3 minutes. The optimal dosage is determined for each patient by a dose titration procedure and lies in the range 0.2 to 1.0mg in anaesthesiology, and 0.1 to 2.0mg in intensive care use. Despite its short elimination half-life of around 1 hour, after general anaesthesia or conscious to moderate sedation for short procedures, a single dose of flumazenil is usually sufficient to attain and maintain the desired level of consciousness. After intoxication with high benzodiazepine doses, the duration of effect of a single dose of flumazenil is not expected to exceed 1 hour. In such cases, the period of wakefulness can be prolonged as necessary by repeated low intravenous doses of flumazenil or by infusion (0.1 mg/hour). Flumazenil is well tolerated both systemically and locally. The only adverse events seen with greater frequency after flumazenil compared with placebo were nausea and/or vomiting after general anaesthesia, although the incidence of actual vomiting was not significantly different between the 2 groups. Since these effects were virtually absent in studies of intensive care patients and after sedation for short procedures, and were not seen in tolerability studies in healthy volunteers receiving intravenous bolus doses of up to 100mg, there may be a link between these symptoms and the other agents used in general anaesthesia, some of which have well-known emetic properties. Thus, flumazenil provides a safe and effective means of attenuating or reversing the CNS-depressant effects of benzodiazepines whenever indicated, e.g. following benzodiazepine-induced general anaesthesia, conscious sedation, or after benzodiazepine overdose, either alone or in combination with other agents.(ABSTRACT TRUNCATED AT 400 WORDS)
Ex Output:
Which drug should be used as an antidote in benzodiazepine overdose?
Ex Input:
Associacao Desportiva Bahia de Feira play their home games at Estadio Municipal Alberto Oliveira, nicknamed Estadio Joia da Princesa.
Ex Output:
|
In what stadium does Associação Desportiva Bahia de Feira play home games?
| 1
|
NIv2
|
task470_mrqa_question_generation
|
fs_opt
|
Given the task definition, example input & output, solve the new input case.
Given a context passage, generate a question from the passage such that its answer is shortest continous span from the passage.
Example: In 1582 the united provinces invited francis, duke of anjou to lead them; but after a failed attempt to take antwerp in 1583, the duke left the netherlands again. after the assassination of william of orange (10 july 1584), both henry iii of france and elizabeth i of england declined the offer of sovereignty. however, the latter agreed to turn the united provinces into a protectorate of england (treaty of nonsuch, 1585), and sent the earl of leicester as governor-general. this was unsuccessful and in 1588 the provinces became a confederacy. the union of utrecht is regarded as the foundation of the republic of the seven united provinces, which was not recognized by the spanish empire until the peace of westphalia in 1648.
Output: In what year did francis, duke of anjou leave the netherlands?
The generated question is perfect. Because the question is based on second sentence of the input passage and its answer is 1583.
New input case for you: The history of the atom begins around 450 B.C. with a Greek philosopher named Democritus (see Figure 5.7). Democritus wondered what would happen if you cut a piece of matter, such as an apple, into smaller and smaller pieces. He thought that a point would be reached where matter could not be cut into still smaller pieces. He called these "uncuttable" pieces atomos. This is where the modern term atom comes from. Democritus was an important philosopher. However, he was less influential than the Greek philosopher Aristotle, who lived about 100 years after Democritus. Aristotle rejected Democrituss idea of atoms. In fact, Aristotle thought Around 1800, a British chemist named John Dalton revived Democrituss early ideas about the atom. Dalton is pictured in Figure 5.8. He made a living by teaching and just did research in his spare time. Nonetheless, from his research results, he developed one of the most important theories in science. Dalton did many experiments that provided evidence for atoms. For example, he studied the pressure of gases. He concluded that gases must consist of tiny particles in constant motion. Dalton also researched the properties of compounds. He showed that a compound always consists of the same elements in the same ratio. On the other hand, different compounds always consist of different elements or ratios. This can happen, Dalton reasoned, only if elements are made of tiny particles that can combine in an endless variety of ways. From his research, Dalton developed a theory of the atom. You can learn more about Dalton and his research by watching the video at this URL: (9:03). MEDIA Click image to the left or use the URL below. URL: The atomic theory Dalton developed consists of three ideas: All substances are made of atoms. Atoms are the smallest particles of matter. They cannot be divided into smaller particles. They also cannot be created or destroyed. All atoms of the same element are alike and have the same mass. Atoms of different elements are different and have different masses. Atoms join together to form compounds. A given compound always consists of the same kinds of atoms in the same ratio. Daltons theory was soon widely accepted. Most of it is still accepted today. The only part that is no longer accepted is his idea that atoms are the smallest particles. Scientists now know that atoms consist of even smaller particles. Dalton incorrectly thought that atoms are tiny solid particles of matter. He used solid wooden balls to model them. The sketch in the Figure 5.9 shows how Daltons model atoms looked. He made holes in the balls so they could be joined together with hooks. In this way, the balls could be used to model compounds. When later scientists discovered subatomic particles (particles smaller than the atom itself), they realized that Daltons models were too simple. They didnt show that atoms consist of even smaller particles. Models including these smaller particles were later developed. The next major advance in the history of the atom was the discovery of electrons. These were the first subatomic particles to be identified. They were discovered in 1897 by a British physicist named J. J. Thomson. You can learn more about Thomson and his discovery at this online exhibit: . Thomson was interested in electricity. He did experiments in which he passed an electric current through a vacuum tube. The experiments are described in Figure 5.10. Thomsons experiments showed that an electric current consists of flowing, negatively charged particles. Why was this discovery important? Many scientists of Thomsons time thought that electric current consists of rays, like rays of light, and that it is positive rather than negative. Thomsons experiments also showed that the negative particles are all alike and smaller than atoms. Thomson concluded that the negative particles couldnt be fundamental units of matter because they are all alike. Instead, they must be parts of atoms. The negative particles were later named electrons. Thomson knew that atoms are neutral in electric charge. So how could atoms contain negative particles? Thomson thought that the rest of the atom must be positive to cancel out the negative charge. He said that an atom is like
Output:
|
In the plum pudding model of the atom, the plums represent
| 1
|
NIv2
|
task470_mrqa_question_generation
|
fs_opt
|
Given a context passage, generate a question from the passage such that its answer is shortest continous span from the passage.
Is it time to kick Russia out of the BRICs ? If so, it may end up sounding like a famous ball-point pen maker-BIC. An argument is being made that Goldman Sach's famous marketing device ,the BRICs, should really be the BICs. "Is Russia really worth the name BRICs?" asks Anders Aslund, senior fellow at the Peterson Institute for International Economics, in an article for Foreigh Policy. Aslund, who is also co-author with Andrew Kuchins of "The Russian Balance Sheet", thinks the Russia of Putin and Medvedev is just not worthy of inclusion alongside Brazil, India and China in the list of future economic powerhouses. He writes: "The country's economic performance has fallen to such a weak level that one must ask whether it has any say at all on the global economy, compared with the other members of its group. I have just returned from Moscow, which is always dull around this season. For the last seven years, Russia has taken very few measures to improve its economy. Instead, the state has been living on oil and gas. " Economically, Aslund has the numbers on his side. The International Monetary Fund figures that the Russian economy will fall by 6.7 percent in 2009, while China will grow 8.5 percent and India 5.4 percent. There is less of a case for Brazil, with a fall of 0.7 percent, but it is still doing far better than Russia. But the BRICs are not just about economy. As is mentioned above, it is a marketing device to encourage investors to focus on the big promising players. From an investment standpoint, it could be argued that Russia is leading the BRICs. Its stock market is up 128 percent this year while around 80 percent is for the other three. At very least, however, Russia's economic underperformance and stock market outperfoumance does suggest it is indeed one of the group.
According to the passage, which country will enjoy the biggest increase in 2009?
Forces deployed to the first Gulf War report more ill health than veterans who did not serve there. Many studies of post-Gulf morbidity are based on relatively small sample sizes and selection bias is often a concern. In a setting where selection bias relating to the ill health of veterans may be reduced, we: i) examined self-reported adult ill health in a large sample of male UK Gulf War veterans and a demographically similar non-deployed comparison group; and ii) explored self-reported ill health among veterans who believed that they had Gulf War syndrome. This study uses data from a retrospective cohort study of reproduction and child health in which a validated postal questionnaire was sent to all UK Gulf War veterans (GWV) and a comparison cohort of Armed Service personnel who were not deployed to the Gulf (NGWV). The cohort for analysis comprises 42,818 males who responded to the questionnaire. We confirmed that GWV report higher rates of general ill health. GWV were significantly more likely to have reported at least one new medical symptom or disease since 1990 than NGWV (61% versus 37%, OR 2.7, 95% CI 2.5-2.8). They were also more likely to report higher numbers of symptoms. The strongest associations were for mood swings (OR 20.9, 95%CI 16.2-27.0), memory loss/lack of concentration (OR 19.6, 95% CI 15.5-24.8), night sweats (OR 9.9, 95% CI 6.5-15.2), general fatigue (OR 9.6, 95% CI 8.3-11.1) and sexual dysfunction (OR 4.6, 95%CI 3.2-6.6). 6% of GWV believed they had Gulf War syndrome (GWS), and this was associated with the highest symptom reporting. Increased levels of reported ill health among GWV were confirmed. This study was the first to use a questionnaire which did not focus specifically on the veterans' symptoms themselves. Nevertheless, the results are consistent with those of other studies of post-Gulf war illness and thus strengthen overall findings in this area of research. Further examination of the mechanisms underlying the reporting of ill health is required.
What memory problems are reported in the " Gulf war syndrome"
Youve probably blown soap bubbles like the child in Figure 4.1. In some ways, the thin film of soap molecules that forms a bubble resembles the cell membrane. Like the soap film, the cell membrane consists of a thin skin of molecules. You can see a model of the cell membrane in Figure below. The molecules that make up the cell membrane are mainly phospholipids. There are two layers of phospholipids. They are arranged so the lipid tails are on the inside of the membrane. They make the interior of the membrane hydrophobic, or "water fearing". The lipid heads point toward the outside of the membrane. The make the outer surfaces of the membrane hydrophilic, or "water loving". Different types of proteins are embedded in the lipid layers. The proteins are needed to help transport many substances across the membrane. The passage of a substance through a cell membrane is called transport. There are two basic ways that transport can occur: passive transport and active transport. For a good video introduction to passive and active transport, click on this link: . MEDIA Click image to the left or use the URL below. URL: Passive transport occurs when a substance passes through the cell membrane without needing any energy to pass through. This happens when a substance moves from an area where it is more concentrated to an area where it is less concentrated. Concentration is the number of particles of a substance in a given volume. Lets say you dissolve a teaspoon of salt in a cup of water. Then you dissolve two teaspoons of salt in another cup of water. The second solution will have a higher concentration of salt. Why does passive transport require no energy? A substance naturally moves from an area of higher to lower concentration. This is known as moving down the concentration gradient. The process is called diffusion. Its a little like a ball rolling down a hill. The ball naturally rolls from a higher to lower position without any added energy. You can see diffusion if you place a few drops of food coloring in a pan of water. Even without shaking or stirring, the food coloring gradually spreads throughout the water in the pan. Some substances can also diffuse through a cell membrane. This can occur in two ways: simple diffusion or facilitated diffusion. Simple diffusion occurs when a substance diffuses through a cell membrane without any help from other molecules. The substance simply passes through tiny spaces in the membrane. It moves from the side of the membrane where it is more concentrated to the side where it is less concentrated. You can see how this happens in Figure 4.2. Substances that cross cell membranes by simple diffusion must squeeze between the lipid molecules in the mem- brane. As a result, the diffusing molecules must be very small. Oxygen (O2 ) and carbon dioxide (CO2 ) are examples of molecules that can cross cell membranes this way. When you breathe in, oxygen is more concentrated in the air in your lungs than it is in your blood. So oxygen diffuses from your lungs to your blood. The reverse happens with carbon dioxide. Carbon dioxide is more concentrated in your blood than it is in the air in your lungs. So carbon dioxide diffuses out of your blood to your lungs. Hydrophilic molecules and very large molecules cant pass through the cell membrane by simple diffusion. They need help to pass through the membrane. The help is provided by proteins called transport proteins. This process is known as facilitated diffusion. There are two types of transport proteins: channel proteins and carrier proteins. They work in different ways. You can see how they work in Figure 4.3. A channel protein forms a tiny hole called a pore in the cell membrane. This allows water or hydrophilic molecules to bypass the hydrophobic interior of the membrane. A carrier protein binds with a diffusing molecule. This causes the carrier protein to change shape. As it does, it carries the molecule across the membrane. This allows large molecules to pass through the cell membrane. Osmosis is the special case of the diffusion of water. Its an important means of transport in cells because the fluid inside and outside cells is mostly water
|
_______passage of a substance through a cell membrane from an area of higher to lower concentration that
| 0
|
NIv2
|
task470_mrqa_question_generation
|
fs_opt
|
TASK DEFINITION: Given a context passage, generate a question from the passage such that its answer is shortest continous span from the passage.
PROBLEM: Alfred Wegener, born in 1880, was a meteorologist and explorer. In 1911, Wegener found a scientific paper that listed identical plant and animal fossils on opposite sides of the Atlantic Ocean. Intrigued, he then searched for and found other cases of identical fossils on opposite sides of oceans. The explanation put out by the scientists of the day was that land bridges had once stretched between these continents. Instead, Wegener pondered the way Africa and South America appeared to fit together like puzzle pieces. Other scientists had suggested that Africa and South America had once been joined, but Wegener was the ideas most dogged supporter. Wegener amassed a tremendous amount of evidence to support his hypothesis that the continents had once been joined. Imagine that youre Wegeners colleague. What sort of evidence would you look for to see if the continents had actually been joined and had moved apart? Here is the main evidence that Wegener and his supporters collected for the continental drift hypothesis: The continents appear to fit together. Ancient fossils of the same species of extinct plants and animals are found in rocks of the same age but are on continents that are now widely separated (Figure 1.1). Wegener proposed that the organisms had lived side by side, but that the lands had moved apart after they were dead and fossilized. His critics suggested that the organisms moved over long-gone land bridges, but Wegener thought that the organisms could not have been able to travel across the oceans. Fossils of the seed fern Glossopteris were too heavy to be carried so far by wind. Mesosaurus was a swimming reptile, but could only swim in fresh water. Cynognathus and Lystrosaurus were land reptiles and were unable to swim. Wegener used fossil evidence to support his continental drift hypothesis. The fos- sils of these organisms are found on lands that are now far apart. Identical rocks, of the same type and age, are found on both sides of the Atlantic Ocean. Wegener said the rocks had formed side by side and that the land had since moved apart. Mountain ranges with the same rock types, structures, and ages are now on opposite sides of the Atlantic Ocean. The Appalachians of the eastern United States and Canada, for example, are just like mountain ranges in eastern Greenland, Ireland, Great Britain, and Norway (Figure 1.2). Wegener concluded that they formed as a single mountain range that was separated as the continents drifted. Grooves and rock deposits left by ancient glaciers are found today on different continents very close to the Equator. This would indicate that the glaciers either formed in the middle of the ocean and/or covered most of the Earth. Today, glaciers only form on land and nearer the poles. Wegener thought that the glaciers were centered over the southern land mass close to the South Pole and the continents moved to their present positions later on. The similarities between the Appalachian and the eastern Greenland mountain ranges are evidences for the continental drift hypothesis. Coral reefs and coal-forming swamps are found in tropical and subtropical environments, but ancient coal seams and coral reefs are found in locations where it is much too cold today. Wegener suggested that these creatures were alive in warm climate zones and that the fossils and coal later drifted to new locations on the continents. Wegener thought that mountains formed as continents ran into each other. This got around the problem of the leading hypothesis of the day, which was that Earth had been a molten ball that bulked up in spots as it cooled (the problem with this idea was that the mountains should all be the same age and they were known not to be). Click image to the left or use the URL below. URL:
SOLUTION: the coast of south america fits closely to this continent like a puzzle piece.
PROBLEM: Munich sincerely invites you to join the 2016 0ktoberfest--the biggest celebration of its kind in Europe. Drink beer by the liter, eat traditional Bavarian food, listen to traditional Bavarian music as well as more up-to-date music, and enjoy yourself with hundreds of other people from all over the world, dancing and singing the hours away. Oktoberfest 2016 begins on Saturday 17th September and runs through to Monday 3rd October 2016. Don't miss the events during Oktoberfest! Grand entry of the Oktoberfest landlords and breweries Date: Saturday, 17th September 2016 Duration: about 45 minutes This is the official prelude to the opening of the Oktoberfest and involves about 1,000 participants, including the landlords' families in decorated carriages, the magnificent horse-drawn drays, waitresses on decorated floats and all the beer tent bands. Oktoberfest Costume and Riflemen-s Parade Date: Sunday, 18th September 2016 Duration:2-2 1/2 hours, about 8000 performers,7 km distance A varied succession of regional costume groups, "troops" in historical uniforms, marching bands, riflemen, thoroughbred horses, oxen, cows, goats, floats displaying typical local traditions and historic carriages all pass by in a 7-kilometer-long procession through the streets of the city center. Open-Air Oktoberfest Music Date: Sunday, 25th September 2016 Place: on the steps of the Bavaria statue At the traditional open-air concert on the second Sunday of the Oktoberfest, all the instruments that make up typical Bavarian wind band music can be heard. The bands from all of the tents come together at the steps under the Bavaria statue to play the most well-known songs and marches of Oktoberfest together while being conducted by distinguished Munich personalities.
SOLUTION: When will visitors see costume soldiers marching on the street?
PROBLEM: Artangel is a London-based arts organisation founded in 1985 by Roger Took.
SOLUTION:
|
What is the name of the founder of Artangel?
| 8
|
NIv2
|
task470_mrqa_question_generation
|
fs_opt
|
Teacher: Given a context passage, generate a question from the passage such that its answer is shortest continous span from the passage.
Teacher: Now, understand the problem? If you are still confused, see the following example:
In 1582 the united provinces invited francis, duke of anjou to lead them; but after a failed attempt to take antwerp in 1583, the duke left the netherlands again. after the assassination of william of orange (10 july 1584), both henry iii of france and elizabeth i of england declined the offer of sovereignty. however, the latter agreed to turn the united provinces into a protectorate of england (treaty of nonsuch, 1585), and sent the earl of leicester as governor-general. this was unsuccessful and in 1588 the provinces became a confederacy. the union of utrecht is regarded as the foundation of the republic of the seven united provinces, which was not recognized by the spanish empire until the peace of westphalia in 1648.
Solution: In what year did francis, duke of anjou leave the netherlands?
Reason: The generated question is perfect. Because the question is based on second sentence of the input passage and its answer is 1583.
Now, solve this instance: The evolutionarily conserved histone variant H2A.Z has an important role in the regulation of gene expression and the establishment of a buffer to the spread of silent heterochromatin. Saccharomyces cerevisiae Swr1, a Swi2/Snf2-related ATPase, is the catalytic core of a multisubunit chromatin remodeling enzyme, called the SWR1 complex, that efficiently replaces conventional histone H2A in nucleosomes with histone H2A.Z. Swr1 is required for the deposition of histone H2A.Z at stereotypical promoter locations in vivo, and Swr1 and H2A.Z commonly regulate a subset of yeast genes. Here, we describe an integrated nucleosome assembly-histone replacement system whereby histone exchange by chromatin remodeling activities may be analyzed in vitro. The system demonstrates ATP- and SWR1-complex-dependent replacement of histone H2A for histone H2A.Z on a preassembled nucleosome array. This system may also be adapted to analyze dynamic interactions between chromatin remodeling and modifying enzymes, histone chaperones, and nucleosome substrates containing canonical, variant, or covalently modified histones.
Student:
|
Which protein mediates the replacement of H2A by H2A.Z in the yeast Saccharomyces cerevisiae?
| 2
|
NIv2
|
task470_mrqa_question_generation
|
fs_opt
|
instruction:
Given a context passage, generate a question from the passage such that its answer is shortest continous span from the passage.
question:
The Yellow River Piano Concerto (simplified Chinese: ; traditional Chinese: ; pinyin: Huang He xiezouqu) is a piano concerto arranged by a collaboration between musicians including Yin Chengzong and Chu Wanghua, and based on the Yellow River Cantata by composer Xian Xinghai.
answer:
What instrument is Yellow River Piano Concerto scored for?
question:
The French Revolution broke out in 1789. At the time France was in a crisis. The government was badly run and people's lives were miserable. King Louis XIV tried to control the national parliament and raise more taxes. But his effort failed. He ordered his troops to Versailles. The people thought that Louis intended to put down the Revolution by force. On July 14, 1789, they stormed and took the Bastille, where political prisoners were kept. Ever since that day, July 14 has been the French National Day. Louis tried to flee the country in 1792, to get support from Austria and Prussia. However, he was caught and put in prison. In September 1792, the monarchy was abolished _ . In the same year, Louis was executed. A few months later his wife, Marie also had her head cut off. The Revolution of France had frightened the other kings of Europe. Armies from Austria and Prussia began to march against France. The French raised republican armies to defend the nation. The Revolution went through a period of terror. Thousands of people lost their lives. In the end, power passed to Napoleon Bonaparte.
answer:
What's this passage about?
question:
Lewy bodies, neuropathological hallmarks of Parkinson's disease and dementia with Lewy bodies, comprise alpha-synuclein filaments and other less defined proteins. Characterization of Lewy body proteins that interact with alpha-synuclein may provide insight into the mechanism of Lewy body formation. Double immunofluorescence labeling and confocal microscopy revealed approximately 80% of cortical Lewy bodies contained microtubule-associated protein 1B (MAP-1B) that overlapped with alpha-synuclein. Lewy bodies were isolated using an immunomagnetic technique from brain tissue of patients dying with dementia with Lewy bodies. Lewy body proteins were resolved by polyacrylamide gel electrophoresis. Immunoblotting confirmed the presence of MAP-1B and alpha-synuclein in purified Lewy bodies. Direct binding studies revealed a high affinity interaction (IC(50) approximately 20 nm) between MAP-1B and alpha-synuclein. The MAP-1B-binding sites were mapped to the last 45 amino acids of the alpha-synuclein C terminus. MAP-1B also bound in vitro assembled alpha-synuclein fibrils. Thus, MAP-1B may be involved in the pathogenesis of Lewy bodies via its interaction with monomeric and fibrillar alpha-synuclein.
answer:
|
Which is the primary protein component of Lewy bodies?
| 9
|
NIv2
|
task470_mrqa_question_generation
|
fs_opt
|
Given a context passage, generate a question from the passage such that its answer is shortest continous span from the passage.
One example is below.
Q: In 1582 the united provinces invited francis, duke of anjou to lead them; but after a failed attempt to take antwerp in 1583, the duke left the netherlands again. after the assassination of william of orange (10 july 1584), both henry iii of france and elizabeth i of england declined the offer of sovereignty. however, the latter agreed to turn the united provinces into a protectorate of england (treaty of nonsuch, 1585), and sent the earl of leicester as governor-general. this was unsuccessful and in 1588 the provinces became a confederacy. the union of utrecht is regarded as the foundation of the republic of the seven united provinces, which was not recognized by the spanish empire until the peace of westphalia in 1648.
A: In what year did francis, duke of anjou leave the netherlands?
Rationale: The generated question is perfect. Because the question is based on second sentence of the input passage and its answer is 1583.
Q: Penobscot tribal chiefs expressed a willingness to enter peace talks with Lieutenant Governor Dummer in December 1724. They were opposed in this by French authorities, who continued to encourage the conflict, but Massachusetts Lieutenant Governor Dummer announced a cessation of hostilities on 31 July 1725 following negotiations in March.:83 The terms of this preliminary agreement were negotiated by Dummer and Chiefs Loron and Wenemouet and applied only to the Penobscots at first. They were allowed to retain Jesuit priests, but the two parties were in disagreement concerning land titles and British sovereignty over the Wabanakis. The written agreement was translated into Abenaki by French Jesuit Etienne Lauverjat; Chief Loron immediately repudiated it, specifically rejecting claims of British sovereignty over him. Despite his disagreement, Loron pursued peace, sending wampum belts to other tribal leaders, although his envoys were unsuccessful in reaching Gray Lock, who continued his raiding expeditions. Peace treaties were signed in Maine on 15 December 1725 and in Nova Scotia on 15 June 1726, involving a large number of tribal chiefs. The peace was reconfirmed by all except Gray Lock at a major gathering at Falmouth in the summer of 1727; other tribal envoys claimed that they were not able to locate him. Gray Lock's activity came to an end in 1727, after which time he disappears from English records.
A:
|
At what event was Gray Lock discovered to be missing?
| 9
|
NIv2
|
task470_mrqa_question_generation
|
fs_opt
|
Detailed Instructions: Given a context passage, generate a question from the passage such that its answer is shortest continous span from the passage.
See one example below:
Problem: In 1582 the united provinces invited francis, duke of anjou to lead them; but after a failed attempt to take antwerp in 1583, the duke left the netherlands again. after the assassination of william of orange (10 july 1584), both henry iii of france and elizabeth i of england declined the offer of sovereignty. however, the latter agreed to turn the united provinces into a protectorate of england (treaty of nonsuch, 1585), and sent the earl of leicester as governor-general. this was unsuccessful and in 1588 the provinces became a confederacy. the union of utrecht is regarded as the foundation of the republic of the seven united provinces, which was not recognized by the spanish empire until the peace of westphalia in 1648.
Solution: In what year did francis, duke of anjou leave the netherlands?
Explanation: The generated question is perfect. Because the question is based on second sentence of the input passage and its answer is 1583.
Problem: A physical change in matter is a change in one or more of matters physical properties. Glass breaking is just one example of a physical change. Some other examples are shown in Figure 3.16 and in the video below. In each example, matter may look different after the change occurs, but its still the same substance with the same chemical properties. For example, smaller pieces of wood have the ability to burn just as larger logs do. MEDIA Click image to the left or use the URL below. URL: Because the type of matter remains the same with physical changes, the changes are often easy to undo. For example, braided hair can be unbraided again. Melted chocolate can be put in a fridge to re-harden. Dissolving salt in water is also a physical change. How do you think you could undo it? Did you ever make a "volcano," like the one in Figure 3.17, using baking soda and vinegar? What happens when the two substances combine? They produce an eruption of foamy bubbles. This happens because of a chemical change. A chemical change occurs when matter changes chemically into an entirely different substance with different chemical properties. When vinegar and baking soda combine, they form carbon dioxide, a gas that causes the bubbles. Its the same gas that gives soft drinks their fizz. Not all chemical changes are as dramatic as this "volcano." Some are slower and less obvious. Figure 3.18 and the video below show other examples of chemical changes. MEDIA Click image to the left or use the URL below. URL: How can you tell whether a chemical change has occurred? Often, there are clues. Several are demonstrated in Figures 3.17 and 3.18 and in the video below. MEDIA Click image to the left or use the URL below. URL: To decide whether a chemical change has occurred, look for these signs: Gas bubbles are released. (Example: Baking soda and vinegar mix and produce bubbles.) Something changes color. (Example: Leaves turn from green to other colors.) An odor is produced. (Example: Logs burn and smell smoky.) A solid comes out of a solution. (Example: Eggs cook and a white solid comes out of the clear liquid part of the egg.) Because chemical changes produce new substances, they often cannot be undone. For example, you cant change a fried egg back to a raw egg. Some chemical changes can be reversed, but only by other chemical changes. For example, to undo the tarnish on copper pennies, you can place them in vinegar. The acid in the vinegar reacts with the tarnish. This is a chemical change that makes the pennies bright and shiny again. You can try this yourself at home to see how well it works. If you build a campfire, like the one in Figure 3.19, you start with a large stack of sticks and logs. As the fire burns, the stack slowly shrinks. By the end of the evening, all thats left is a small pile of ashes. What happened to the matter that you started with? Was it destroyed by the flames? It may seem that way, but in fact, the same amount of matter still exists. The wood changed not only to ashes but also to carbon dioxide, water vapor, and other gases. The gases floated off into the air, leaving behind just the ashes. Assume you had measured the mass of the wood before you burned it. Assume you had also trapped the gases released by the burning wood and measured their mass and the mass of the ashes. What would you find? The ashes and gases combined have the same mass as the wood you started with. This example illustrates the law of conservation of mass. The law states that matter cannot be created or destroyed. Even when matter goes through physical or chemical changes, the total mass of matter always remains the same. (In the chapter Nuclear Chemistry, you will learn about nuclear reactions, in which mass is converted into energy. But other than that, the law of conservation of mass holds
Solution:
|
After a physical change, matter may
| 4
|
NIv2
|
task470_mrqa_question_generation
|
fs_opt
|
Given a context passage, generate a question from the passage such that its answer is shortest continous span from the passage.
Example: In 1582 the united provinces invited francis, duke of anjou to lead them; but after a failed attempt to take antwerp in 1583, the duke left the netherlands again. after the assassination of william of orange (10 july 1584), both henry iii of france and elizabeth i of england declined the offer of sovereignty. however, the latter agreed to turn the united provinces into a protectorate of england (treaty of nonsuch, 1585), and sent the earl of leicester as governor-general. this was unsuccessful and in 1588 the provinces became a confederacy. the union of utrecht is regarded as the foundation of the republic of the seven united provinces, which was not recognized by the spanish empire until the peace of westphalia in 1648.
Example solution: In what year did francis, duke of anjou leave the netherlands?
Example explanation: The generated question is perfect. Because the question is based on second sentence of the input passage and its answer is 1583.
Problem: Despite the Portuguese proclaiming themselves as hostile to the Spanish crown, the VOC nevertheless took the opportunity to prise away the string of coastal fortresses that comprised the Portuguese Empire: Malacca finally succumbed in 1641. Important battles also took place in the South China sea, initially with combined fleets of Dutch and English vessels, and subsequently exclusively Dutch ships assaulting Macau. Dutch attempts to capture Macau, to force China to replace the Portuguese or to settle the Pescadores failed, in part because of the long-standing diplomacy between the Portuguese and the Ming, but the Dutch were ultimately successful in acquiring the monopoly of trade with Japan. while the Dutch were unable in four attempts to capture Macau from where Portugal monopolised the lucrative China-Japan trade. The Dutch established a colony at Tayouan in 1624, present-day Anping in the south of Taiwan, known to the Portuguese as Formosa and in 1642 the Dutch took northern Formosa from the Spanish by force. The Dutch intervened in the Sinhalese-Portuguese War on Ceylon from 1638 onwards, initially as allies of the Kingdom of Kandy against Portugal. The Dutch conquered Batticaloa in 1639 and Galle in 1640 before the alliance broke down. After a period of triangular warfare between the Dutch, Portuguese and Kandyans, the alliance was remade in 1649. After exploiting and then double-crossing their Kandyan allies, the Dutch were able to capture Colombo in 1656 and drove the last Portuguese from Ceylon in 1658. Sporadic warfare with Kandy continued for over a century.
|
Solution: Which European power were the Dutch attempting to take territory from before launching their assault on Spanish territory?
| 5
|
NIv2
|
task470_mrqa_question_generation
|
fs_opt
|
Teacher: Given a context passage, generate a question from the passage such that its answer is shortest continous span from the passage.
Teacher: Now, understand the problem? If you are still confused, see the following example:
In 1582 the united provinces invited francis, duke of anjou to lead them; but after a failed attempt to take antwerp in 1583, the duke left the netherlands again. after the assassination of william of orange (10 july 1584), both henry iii of france and elizabeth i of england declined the offer of sovereignty. however, the latter agreed to turn the united provinces into a protectorate of england (treaty of nonsuch, 1585), and sent the earl of leicester as governor-general. this was unsuccessful and in 1588 the provinces became a confederacy. the union of utrecht is regarded as the foundation of the republic of the seven united provinces, which was not recognized by the spanish empire until the peace of westphalia in 1648.
Solution: In what year did francis, duke of anjou leave the netherlands?
Reason: The generated question is perfect. Because the question is based on second sentence of the input passage and its answer is 1583.
Now, solve this instance: With the recent introduction of inhibitors of mammalian target of rapamycin (mTOR) in oncology, distinct cutaneous and oral adverse events have been identified. In fact, stomatitis and rash are documented as the most frequent and potentially dose-limiting side effects. Clinically, mTOR inhibitor-associated stomatitis (mIAS) more closely resembles aphthous stomatitis than oral mucositis due to conventional anticancer therapies. While most cases of mIAS are mild to moderate and self-limiting, more severe and persistent mIAS can become a dose-limiting toxicity. Small ulcerations may cause significant pain and mucosal sensitivity may occur in the absence of clinical changes. Use of clinical assessment tools that are primarily driven by ulceration size may underestimate mIAS, and assessment should include patient-reported outcomes. This article provides an up-to-date review of the clinical presentation, terminology, pathogenesis, assessment and management of mIAS and other mTOR inhibitor-associated oral adverse events. In addition, areas of future research are considered.
Student:
|
What does mTOR stands for?
| 2
|
NIv2
|
task470_mrqa_question_generation
|
fs_opt
|
Part 1. Definition
Given a context passage, generate a question from the passage such that its answer is shortest continous span from the passage.
Part 2. Example
In 1582 the united provinces invited francis, duke of anjou to lead them; but after a failed attempt to take antwerp in 1583, the duke left the netherlands again. after the assassination of william of orange (10 july 1584), both henry iii of france and elizabeth i of england declined the offer of sovereignty. however, the latter agreed to turn the united provinces into a protectorate of england (treaty of nonsuch, 1585), and sent the earl of leicester as governor-general. this was unsuccessful and in 1588 the provinces became a confederacy. the union of utrecht is regarded as the foundation of the republic of the seven united provinces, which was not recognized by the spanish empire until the peace of westphalia in 1648.
Answer: In what year did francis, duke of anjou leave the netherlands?
Explanation: The generated question is perfect. Because the question is based on second sentence of the input passage and its answer is 1583.
Part 3. Exercise
Alison Gopnik (born June 16, 1955) is an American professor of psychology and affiliate professor of philosophy at the University of California, Berkeley.
Answer:
|
What is Alison Gopnik's place of employment?
| 7
|
NIv2
|
task470_mrqa_question_generation
|
fs_opt
|
Teacher: Given a context passage, generate a question from the passage such that its answer is shortest continous span from the passage.
Teacher: Now, understand the problem? If you are still confused, see the following example:
In 1582 the united provinces invited francis, duke of anjou to lead them; but after a failed attempt to take antwerp in 1583, the duke left the netherlands again. after the assassination of william of orange (10 july 1584), both henry iii of france and elizabeth i of england declined the offer of sovereignty. however, the latter agreed to turn the united provinces into a protectorate of england (treaty of nonsuch, 1585), and sent the earl of leicester as governor-general. this was unsuccessful and in 1588 the provinces became a confederacy. the union of utrecht is regarded as the foundation of the republic of the seven united provinces, which was not recognized by the spanish empire until the peace of westphalia in 1648.
Solution: In what year did francis, duke of anjou leave the netherlands?
Reason: The generated question is perfect. Because the question is based on second sentence of the input passage and its answer is 1583.
Now, solve this instance: De Quervain's disease has different clinical features. Different tests have been described in the past, the most popular test being the Eichhoff's test, often wrongly named as the Finkelstein's test. Over the years, a misinterpretation has occurred between these two tests, the latter being confused with the first. To compare the Eichhoff's test with a new test, the wrist hyperflexion and abduction of the thumb test, we set up a prospective study over a period of three years for a cohort of 100 patients (88 women, 12 men) presenting spontaneous pain over the radial side of the styloid of the radius (de Quervain tendinopathy). The purpose of the study was to compare the accuracy of the Eichhoff's test and wrist hyperflexion and abduction of the thumb test to diagnose correctly de Quervain's disease by comparing clinical findings using those tests with the results on ultrasound. The wrist hyperflexion and abduction of the thumb test revealed greater sensitivity (0.99) and an improved specificity (0.29) together with a slightly better positive predictive value (0.95) and an improved negative predictive value (0.67). Moreover, the study showed us that the wrist hyperflexion and abduction of the thumb test is very valuable in diagnosing dynamic instability after successful decompression of the first extensor compartment. Our results support that the wrist hyperflexion and abduction of the thumb test is a more precise tool for the diagnosis of de Quervain's disease than the Eichhoff's test and thus could be adopted to guide clinical diagnosis in the early stages of de Quervain's tendinopathy.
Student:
|
Which disease is diagnosed using the Finkelstein's test?
| 2
|
NIv2
|
task470_mrqa_question_generation
|
fs_opt
|
Detailed Instructions: Given a context passage, generate a question from the passage such that its answer is shortest continous span from the passage.
See one example below:
Problem: In 1582 the united provinces invited francis, duke of anjou to lead them; but after a failed attempt to take antwerp in 1583, the duke left the netherlands again. after the assassination of william of orange (10 july 1584), both henry iii of france and elizabeth i of england declined the offer of sovereignty. however, the latter agreed to turn the united provinces into a protectorate of england (treaty of nonsuch, 1585), and sent the earl of leicester as governor-general. this was unsuccessful and in 1588 the provinces became a confederacy. the union of utrecht is regarded as the foundation of the republic of the seven united provinces, which was not recognized by the spanish empire until the peace of westphalia in 1648.
Solution: In what year did francis, duke of anjou leave the netherlands?
Explanation: The generated question is perfect. Because the question is based on second sentence of the input passage and its answer is 1583.
Problem: The Swc4p protein, encoded by an essential gene, is shared by two chromatin-remodeling complexes in Saccharomyces cerevisiae cells: NuA4 (nucleosome acetyltransferase of H4) and SWR1. The SWR1 complex catalyzes ATP-dependent exchange of the nucleosomal histone H2A for H2AZ (Htz1p). The activity of NuA4 is responsible mainly for the acetylation of the H4 histone but also for the acetylation of H2A and H2AZ. In this work we investigated the role of the Swc4p protein. Using random mutagenesis we isolated a collection of swc4 mutants and showed that the essential function of Swc4p resides in its N-terminal part, within the first 269 amino acids of the 476-amino acid-long protein. We also demonstrated that Swc4p is able to accommodate numerous mutations without losing its functionality under standard growth conditions. However, when swc4 mutants were exposed to methyl methanesulfonate (MMS), hydroxyurea or benomyl, severe growth deficiencies appeared, pointing to an involvement of Swc4p in many chromatin-based processes. The mutants' phenotypes did not result from an impairment of histone acetylation, as in the mutant which bears the shortest isolated variant of truncated Swc4p, the level of overall H4 acetylation was unchanged.
Solution:
|
Which protein mediates the replacement of H2A by H2A.Z in the yeast Saccharomyces cerevisiae?
| 4
|
NIv2
|
task470_mrqa_question_generation
|
fs_opt
|
You will be given a definition of a task first, then an example. Follow the example to solve a new instance of the task.
Given a context passage, generate a question from the passage such that its answer is shortest continous span from the passage.
In 1582 the united provinces invited francis, duke of anjou to lead them; but after a failed attempt to take antwerp in 1583, the duke left the netherlands again. after the assassination of william of orange (10 july 1584), both henry iii of france and elizabeth i of england declined the offer of sovereignty. however, the latter agreed to turn the united provinces into a protectorate of england (treaty of nonsuch, 1585), and sent the earl of leicester as governor-general. this was unsuccessful and in 1588 the provinces became a confederacy. the union of utrecht is regarded as the foundation of the republic of the seven united provinces, which was not recognized by the spanish empire until the peace of westphalia in 1648.
Solution: In what year did francis, duke of anjou leave the netherlands?
Why? The generated question is perfect. Because the question is based on second sentence of the input passage and its answer is 1583.
New input: After a tough win over the Texans, the Steelers stayed home for a game against the Colts. In the first quarter, the Colts scored first as Adam Vinatieri nailed a 31-yard field goal for a 3-0 lead. However, the Steelers took the lead later on in the quarter when Ben Roethlisberger found Markus Wheaton on an 18-yard TD pass for a 7-3 game. In the 2nd quarter, the Steelers would score again increasing their lead as Roethlisberger found Martavis Bryant on a 5-yard TD pass for a 14-3 game. This was followed by William Gay picking off Andrew Luck and returning it 33 yards for a TD as they increased their lead to 21-3. The Colts however responded as Andrew Luck threw a 21-yard TD pass to Dwayne Allen for a 21-10 game. However, the Steelers pulled away as Roethlisberger would find Antonio Brown on 2 consecutive TD passes: from 8 and 47 yards out to increase their lead at first from 28-10 to 35-10. The Colts responded with 10 straight points first being Luck who found T. Y. Hilton on a 28-yard TD Pass for a 35-17 game followed by Vinatieri kicking a 23-yard field goal before halftime to make the score 35-20. The Steelers went back to work in the 3rd quarter as Roethlisberger and Bryant hooked up again on a 2-yard TD pass to increase their lead making the score 42-20. The Colts however were able to come within 8 later on when Ahmad Bradshaw ran for a 12-yard TD followed by Luck finding Donte Moncrief on a 31-yard TD pass to make the score 42-27 and then 42-34. In the 4th quarter, it was all Steelers when a penalty was enforced on Luck in the end zone for a safety making the score 44-34. The Steelers were able to seal the game later on when Roethlisberger found Heath Miller on an 11-yard TD pass for a final score of 51-34. Roethlisberger set franchise records with 522 yards passing and six touchdowns while picking up his 100th victory in his 150th start. Roethlisberger's yardage total was the fourth highest in NFL history. He became the first player in NFL history to go over 500 yards passing twice as the Steelers won consecutive games for the first time this season.
Solution:
|
What quarter did the longest field goal kick of the game happen in?
| 0
|
NIv2
|
task470_mrqa_question_generation
|
fs_opt
|
Given a context passage, generate a question from the passage such that its answer is shortest continous span from the passage.
[EX Q]: One Girl's Confession is a 1953 low-budget film noir released by Columbia Pictures.
[EX A]: What company released One Girl's Confession?
[EX Q]: The motion of an object can be represented by a position-time graph like Graph 1 in the Figure 1.1. In this type of graph, the y-axis represents position relative to the starting point, and the x-axis represents time. A position-time graph shows how far an object has traveled from its starting position at any given time since it started moving. Q: In the Figure 1.1, what distance has the object traveled from the starting point by the time 5 seconds have elapsed? A: The object has traveled a distance of 50 meters. In a position-time graph, the velocity of the moving object is represented by the slope, or steepness, of the graph line. If the graph line is horizontal, like the line after time = 5 seconds in Graph 2 in the Figure 1.2, then the slope is zero and so is the velocity. The position of the object is not changing. The steeper the line is, the greater the slope of the line is and the faster the objects motion is changing. Its easy to calculate the average velocity of a moving object from a position-time graph. Average velocity equals the change in position (represented by d) divided by the corresponding change in time (represented by t): velocity = d t For example, in Graph 2 in the Figure 1.2, the average velocity between 0 seconds and 5 seconds is: d t 25 m 0 m = 5 s0 s 25 m = 5s = 5 m/s velocity =
[EX A]: the slope of a position-time graph can be used to find the moving objects
[EX Q]: One Shell Square is a 51-story, 697-foot (212 m) skyscraper designed in the International style by Skidmore, Owings and Merrill, located at 701 Poydras Street in the Central Business District of New Orleans, Louisiana.
[EX A]:
|
The designer for One Shell Square was?
| 6
|
NIv2
|
task470_mrqa_question_generation
|
fs_opt
|
TASK DEFINITION: Given a context passage, generate a question from the passage such that its answer is shortest continous span from the passage.
PROBLEM: Legislative Studies Quarterly is a quarterly peer-reviewed academic journal published by Wiley-Blackwell and is the official journal of the Legislative Studies Section of the American Political Science Association.
SOLUTION: The publisher that published Legislative Studies Quarterly is what?
PROBLEM: Khin Sok, (Khmer: , born in 1942, Kandal Province, late French colonial Cambodia, died on 10. October 2011 in Paris) was a Cambodian historian, linguist, literature and arts scholar.
SOLUTION: What is the city of birth of Khin Sok?
PROBLEM: 9767 Midsomer Norton (1992 EB1) is an outer main-belt asteroid discovered on March 10, 1992 by Duncan Steel at Siding Spring.
SOLUTION:
|
Who made the discovery of 9767 Midsomer Norton?
| 8
|
NIv2
|
task470_mrqa_question_generation
|
fs_opt
|
TASK DEFINITION: Given a context passage, generate a question from the passage such that its answer is shortest continous span from the passage.
PROBLEM: This Is Jackie DeShannon is an LP album by Jackie DeShannon, released by Imperial Records under catalog number LP-9286 as a monophonic recording in 1965, and later in stereo under catalog number LP-12286 the same year.
SOLUTION: What label was responsible for This Is Jackie DeShannon?
PROBLEM: Modeled after US hot website.com, group buying websites are now popular in China. These websites use the power of group buying to get competitive discounts for a daily deal on some best stuff to do, see, eat and buy in the cities across China. Discounts are available within just one click. Zhao lei, a software engineer in Beijing, loves the one-hour lunch break at noon,as it is the best time for him to check "today's special" at his favorite group buying websites . Sometimes he searches for great deals at directory sites devoted to the new shopping space. Zhao spends around 800 yuan($117.65) on group buying every month, mostly to buy food coupons for eating at some nice restaurants and occasionally to find something fun to do. " I love group buying. In addition to the competitive discounts it offers, it helps me get something fun, exciting and new, and such surprises give me a reason to try something new," he said. When he finds a really good bargain, he will send the link to friends or colleagues through MSN,QQ, or e-mail, or share the information at some social networking websites. In doing so, he often gets a certain cut off the price. At some sites, buyers are invited to leave notes about what they want to buy and the website will consider it if similar applications reach a certain number. That is how Zuo got her digital camera after waiting for two months. "It is cool. I want to buy a new digitgal camera for my trip to Switzerland this winter, but I never expected such cheap prices!" Zuo said.
SOLUTION: What is the passage mainly about?
PROBLEM: Recently mutations in the gene ZFHX1B (SIP1) were shown in patients with "syndromic Hirschsprung disease" with mental retardation (MR) and multiple congenital anomalies (MCA), but it was unclear if Hirschsprung disease is an obligate symptom of these mutations and if the distinct facial phenotype delineated by Mowat et al. [1998: J Med Genet 35: 617-623] is specific for ZFHX1B mutations. In order to address these open questions we analyzed the ZFHX1B gene in five patients, three of whom had "syndromic Hirschsprung disease" two with and one without the facial phenotype described by Mowat et al. [1998], and two of whom had the distinct facial gestalt without Hirschsprung disease. Analyses of microsatellite markers and newly identified SNPs, and/or FISH with BACs from the ZFHX1B region excluded large deletions in all five patients. Direct sequencing demonstrated truncating ZFHX1B mutations in all four patients with the characteristic facial phenotype, but not in the patient with syndromic Hirschsprung disease without the distinct facial appearance. We demonstrate that there is a specific clinical entity with a recognizable facial gestalt, mental retardation and variable MCAs which we propose be called the "Mowat-Wilson syndrome."
SOLUTION:
|
Which gene is responsible for the development of the Mowat-Wilson syndrome?
| 8
|
NIv2
|
task470_mrqa_question_generation
|
fs_opt
|
Given a context passage, generate a question from the passage such that its answer is shortest continous span from the passage.
Example input: In 1582 the united provinces invited francis, duke of anjou to lead them; but after a failed attempt to take antwerp in 1583, the duke left the netherlands again. after the assassination of william of orange (10 july 1584), both henry iii of france and elizabeth i of england declined the offer of sovereignty. however, the latter agreed to turn the united provinces into a protectorate of england (treaty of nonsuch, 1585), and sent the earl of leicester as governor-general. this was unsuccessful and in 1588 the provinces became a confederacy. the union of utrecht is regarded as the foundation of the republic of the seven united provinces, which was not recognized by the spanish empire until the peace of westphalia in 1648.
Example output: In what year did francis, duke of anjou leave the netherlands?
Example explanation: The generated question is perfect. Because the question is based on second sentence of the input passage and its answer is 1583.
Q: Riparian Plaza was designed by Harry Seidler (architect) and Robert Bird Group (structural engineer).
A:
|
By which person Riparian Plaza has been designed?
| 3
|
NIv2
|
task470_mrqa_question_generation
|
fs_opt
|
TASK DEFINITION: Given a context passage, generate a question from the passage such that its answer is shortest continous span from the passage.
PROBLEM: Mega Man Star Force 2, known in Japan as Shooting Star Rockman 2 (2 Ryusei no Rokkuman Tsu), is a video game developed by Capcom for the Nintendo DS handheld game console.
SOLUTION: Who worked on Mega Man Star Force 2?
PROBLEM: The Kaiser Shipyards were seven major shipbuilding yards located on the U.S. west coast during World War II. Kaiser ranked 20th among United States corporations in the value of wartime production contracts.
SOLUTION: Which industry is Kaiser Shipyards associated with?
PROBLEM: Miklos Ajtai (born 2 July 1946) is a computer scientist at the IBM Almaden Research Center, USA.
SOLUTION:
|
What is Miklós Ajtai's place of employment?
| 8
|
NIv2
|
task470_mrqa_question_generation
|
fs_opt
|
instruction:
Given a context passage, generate a question from the passage such that its answer is shortest continous span from the passage.
question:
Presently the Appalachian elktoe is considered critically endangered, and it is unknown if they are still in fact actively reproducing.
answer:
What is the status of Appalachian elktoe?
question:
The tradition of birthday parties started in Europe a long time ago. It was feared that evil spirits were particularly attracted to people on their birthdays. To protect them from harm, friends and family members would come to stay with the birthday person and bring good thoughts and wishes. Giving gifts brought even more good cheer to keep away from the evil spirits. This is how birthday parties began. The following are some countries' birthday traditions: Canada---Putting butter on the nose. In Atlantic Canada, the birthday child's nose is put butter on for good luck. China---Noodles for lunch. The birthday child pays respect to his / her parents and receives a gift of money. Friends and relatives are invited to lunch and noodles are served to wish the birthday child a long life. England---Money cakes. Certain symbolic objects are mixed into the birthday cake as it is being prepared. If your piece of cake has a coin in it, you will be rich. Ireland---Birthday bump . The birthday child is lifted upside down and " bumped" on the floor for good luck. Italy---Pulling ears. The child's ears are pulled as many times as how old he / she is turning. Japan---New clothes. The birthday child wears new clothes to mark the occasion. New Zealand---Birthday claps. After the candles are hit, the happy birthday song is sung loudly and often out of tune and then the birthday person receives a clap for each year he / she has been alive and then one for good luck. The United States---Cake, candles and the birthday song. A cake is made, and candles are put on top based on how old the person is.
answer:
According to the passage, in which country can the birthday children probably receive a gift of money?
question:
Convenient location 5 minutes from Washington ,D.C. and one block to Crystal City METRO ,Crystal City Underground. Alexandria. Free Parking, free Deluxe Continental Breakfast and complimentary Hotel Shuttle Service to Ronald Reagan Washington National Airport. 14000 Jefferson Davis Hwy(endurance on S. Eads St.) Phone (703) 979-3722 DAYS INN ARLINGTON Days Inn Arlington is located two miles from the Pentagon ,Lincoln Memorial .There is a restaurant which serves American style food ,plus two meeting rooms and an outdoor pool. Complimentary shuttle service runs to the Rosslyn Metro Station. Complimentary parking is available on the property .An experienced staff welcomes our guests. Phone(703)525-0300 THE HIGHLANDER MOTOR INN Comfortable rooms at moderate rates . Convenient location only minutes away from Washington area attraction. Near VA Square METRO Station and Ballston Commons Shopping Mall. Free continental breakfast ,free parking. Phone(703)524-4300 HYATT REGENCY CRYSTAL CITY Conveniently located next to Washington National Airport and two miles from Washington D.C. Complimentary Shuttle to and from National Airport ,metro ,local restaurants and shopping .Experience a view to remember at out rooftop restaurants "Chesapeake Grill." Call for Reservations. Phone(073)418-12341
answer:
|
Which hotel is close to airports?
| 9
|
NIv2
|
task470_mrqa_question_generation
|
fs_opt
|
Given a context passage, generate a question from the passage such that its answer is shortest continous span from the passage.
[Q]: Carbon is one of the most common elements found in living organisms. Chains of carbon molecules form the backbones of many organic molecules, such as carbohydrates, proteins, and lipids. Carbon is constantly cycling between living organisms and the atmosphere ( Figure 1.1). The cycling of carbon occurs through the carbon cycle. Living organisms cannot make their own carbon, so how is carbon incorporated into living organisms? In the atmosphere, carbon is in the form of carbon dioxide gas (CO2 ). Recall that plants and other producers capture the carbon dioxide and convert it to glucose (C6 H12 O6 ) through the process of photosynthesis. Then as animals eat plants or other animals, they gain the carbon from those organisms. The chemical equation of photosynthesis is 6CO2 + 6H2 O C6 H12 O6 + 6O2 . How does this carbon in living things end up back in the atmosphere? Remember that we breathe out carbon dioxide. This carbon dioxide is generated through the process of cellular respiration, which has the reverse chemical reaction as photosynthesis. That means when our cells burn food (glucose) for energy, carbon dioxide is released. We, like all animals, exhale this carbon dioxide and return it back to the atmosphere. Also, carbon is released to the atmosphere as an organism dies and decomposes. Cellular respiration and photosynthesis can be described as a cycle, as one uses carbon dioxide (and water) and makes oxygen (and glucose), and the other uses oxygen (and glucose) and makes carbon dioxide (and water). The carbon cycle. The cycling of car- bon dioxide in photosynthesis and cellular respiration are main components of the carbon cycle. Carbon is also returned to the atmosphere by the burning of organic matter (combustion) and fossil fuels and decomposition of organic matter. Millions of years ago, there were so many dead plants and animals that they could not completely decompose before they were buried. They were covered over by soil or sand, tar or ice. These dead plants and animals are organic matter made out of cells full of carbon-containing organic compounds (carbohydrates, lipids, proteins and nucleic acids). What happened to all this carbon? When organic matter is under pressure for millions of years, it forms fossil fuels. Fossil fuels are coal, oil, and natural gas. When humans dig up and use fossil fuels, we have an impact on the carbon cycle ( Figure 1.2). This carbon is not recycled until it is used by humans. The burning of fossil fuels releases more carbon dioxide into the atmosphere than is used by photosynthesis. So, there is more carbon dioxide entering the atmosphere than is coming out of it. Carbon dioxide is known as a greenhouse gas, since it lets in light energy but does not let heat escape, much like the panes of a greenhouse. The increase of greenhouse gasses in the atmosphere is contributing to a global rise in Earths temperature, known as global warming or global climate change.
[A]: when organisms die, what process returns their carbon back into the atmosphere?
[Q]: We're always looking for well-written reviews of books, music, movies, television shows, websites, video games and other products. When writing a review, concentrate on exactly what you liked or didn't like. Give examples of strengths and weaknesses, be descriptive and provide background information on an author, director, actor or musician, if possible. Find professional reviews in magazines or newspapers and see how reviewers deal with their topic, but be sure to express your own voice in your review. Grammar Hint for Reviews: When describing a book, movie, album or anything else, use the present tense. Book Reviews Discuss an author's technique, strengths and weaknesses instead of focusing on the plot. Does the story flow? Is there a strong sense of character and place? Did you stay up until dawn to finish it? Is it good reading for teenagers? What influence did it have on you and why? If you've read other books by the same author, discuss how this book compares. Movie Reviews Think of the major Oscar categories and consider the performances, music, lighting and setting, etc. Do these work together? Did some hold up while others didn't? If the movie is based on a book, discuss whether one is better than the other and why. If the movie is a remake, compare the film to its original. Remember that a well-written movie review should discuss strengths and weaknesses. Some readers may not have seen a movie yet, so don't give away an exciting scene or the ending! College Reviews Begin by providing an overview of the college, including location, size and a description of the campus and/or dorm life. Think about all aspects of your college visit. What academic, athletic and after-class programs are available? What are the students like? What makes the college different from others? Every school has strengths and weaknesses. Be objective. Consider what the school has to offer and who might enjoy or benefit the most from attending there.
[A]: Which aspects should be included in all three reviews?
[Q]: In 2009, 78.5% of Dallas (city) commuters drive to work alone. The 2009 modal share for Dallas (city) commuters are 10.7% for carpooling, 3.9% for transit, 1.9% for walking, and .1% for cycling. In 2015, the American Community Survey estimated modal shares for Dallas (city) commuters of 75.4% for driving alone, 12.8% for carpooling, 3.5% for riding transit, 1.9% for walking, and .2% for cycling. The city of Dallas has a higher than average percentage of households without a car. In 2015, 10.2 percent of Dallas households lacked a car, and decreased to 9.1 percent in 2016. The national average was 8.7 percent in 2016. Dallas averaged 1.59 cars per household in 2016, compared to a national average of 1.8.
[A]:
|
Which group of commuters in 2009 was the largest in Dallas, carpooling or transit?
| 5
|
NIv2
|
task470_mrqa_question_generation
|
fs_opt
|
Given a context passage, generate a question from the passage such that its answer is shortest continous span from the passage.
Example input: In 1582 the united provinces invited francis, duke of anjou to lead them; but after a failed attempt to take antwerp in 1583, the duke left the netherlands again. after the assassination of william of orange (10 july 1584), both henry iii of france and elizabeth i of england declined the offer of sovereignty. however, the latter agreed to turn the united provinces into a protectorate of england (treaty of nonsuch, 1585), and sent the earl of leicester as governor-general. this was unsuccessful and in 1588 the provinces became a confederacy. the union of utrecht is regarded as the foundation of the republic of the seven united provinces, which was not recognized by the spanish empire until the peace of westphalia in 1648.
Example output: In what year did francis, duke of anjou leave the netherlands?
Example explanation: The generated question is perfect. Because the question is based on second sentence of the input passage and its answer is 1583.
Q: Epidemiology of Clostridium difficile is characterized by worldwide increase of C. difficile infections (CDI) and the emergence of new epidemic outbreak strains with the capacity for global spreading. Long-term local surveillance at the University of Saarland Medical Center between 2000 and 2013 shows that the incidence rate of laboratory-confirmed CDI was influenced by local epidemiology as well as by testing strategies. Since 2008, molecular typing of C. difficile was regularly performed for symptomatic hospitalized patients by surface-layer protein A sequence typing (slpAST), which is an established highly standardized technique for genotyping of C. difficile. The results were assigned to known ribotypes for better comparison to international data. It could be demonstrated that distribution of genotypes was different between age groups. Older patients were predominantly infected with ribotype 001 and 027, whereas ribotype 027 was not detected in the pediatric population. Molecular typing of German isolates sent to the advisory laboratory between 2011 and 2013 revealed that ribotype 027 is present with high percentages in most German regions except for the very North. In conclusion, optimized testing of all hospitalized patients with diarrhea should be generally implemented to avoid under-diagnosis of C. difficile infection. Ribotype 027 is highly prevalent in Germany, but its infections are restricted to older patients, while absent in children. Molecular typing of suspected hospital outbreaks and of patients with severe or recurrent disease may help to better understand virulence and epidemic spreading of C. difficile.
A:
|
Which main ribotype of Clostridium difficile is responsible of the recent outbreak?
| 3
|
NIv2
|
task470_mrqa_question_generation
|
fs_opt
|
Given a context passage, generate a question from the passage such that its answer is shortest continous span from the passage.
Ex Input:
There is plenty for kids and teens to do in the Syracuse area during the summer, including some great educational opportunities. Here are the top four. Rosamond Gifford Zoo Camp The zoo offers separate camps for kids. The camps for kindergarteners run from 9 am to 12:30 pm, and cost $115 for zoo members and $135 for non-members. Kids entering 7thand 8thgrades will have half a day from 1 pm to 4:30 pm. The cost is $149 for members and $160 for non-members. All camps feature numerous educational activities and animal encounters. The camps run from August 14 to August 19. Registration starts from July 10 for members and July 15 for non-members. Active Learning Services at Christian Brothers Academy From August 1 to August 5, Christian Brothers Academy will host Active Learning Services from USA Chess. Topics of learning will include Chess Camp (age 5-15), and Video Game Creation Program (age 8-15). Chess Camp promises improved chess skills through chess instructors utilizing demo boards and historic games. Half day sessions will cost $280 for the Computer Camps. A full day of Chess costs $400, and a half day of Chess followed by a half day of Computer Camps cost $430. Syracuse University Summer College From July 5thto August 12th, Syracuse University will host pre-college programs for high school students. The Summer College will offer a wide variety of programs including architecture, engineering and computer science, public communications, and eco-fashion. The programs are taught by the teachers of Syracuse University and include hands-on activities. The costs range from $2325 to $7642. The Sheldon Institute at SUNY Oswego The State University of New York will hold two-week educational enrichment programs for students entering grades2-4 from July 25 to August 5. Children will have a set program featuring art, science, technology, cultural appreciation and writing. Tuition for the programs is only $320 and a downloadable application is available.
Ex Output:
Where can children attend the largest number of programs with low cost?
Ex Input:
One Shell Square is a 51-story, 697-foot (212 m) skyscraper designed in the International style by Skidmore, Owings and Merrill, located at 701 Poydras Street in the Central Business District of New Orleans, Louisiana.
Ex Output:
The designer for One Shell Square was?
Ex Input:
Chronic myeloid leukemia (CML) is a progressive and often fatal myeloproliferative neoplasm. The hallmark of CML is an acquired chromosomal translocation known as the Philadelphia chromosome (Ph), which results in the synthesis of the breakpoint cluster region-Abelson murine leukemia (BCR-ABL) fusion oncoprotein, a constitutively active tyrosine kinase. The introduction of imatinib, a tyrosine kinase inhibitor (TKI) that is specific for BCR-ABL, was a major breakthrough in CML therapy. Although most patients respond to first-line imatinib therapy, some experience loss of response (resistance) or require treatment discontinuation because of toxicity (intolerance). For patients with CML, failure on standard-dose imatinib therapy (400 mg daily), imatinib dose escalation (600-800 mg daily) is a second-line option. However, high-dose imatinib is not an appropriate approach for patients who experience drug toxicity, and there remain questions over the durability of responses achieved with this strategy. Alternative second-line options include the TKIs dasatinib and nilotinib. A substantial amount of long-term data for these agents is available. Although both are potent and specific BCR-ABL TKIs, dasatinib and nilotinib exhibit unique pharmacologic profiles and response patterns relative to different patient characteristics, such as disease stage and BCR-ABL mutation status. To optimize therapeutic benefit, clinicians should select treatment based on each patient's historic response, adverse-event tolerance, and risk factors.
Ex Output:
|
What tyrosine kinase, involved in a Philadelphia- chromosome positive chronic myelogenous leukemia, is the target of Imatinib (Gleevec)?
| 1
|
NIv2
|
task470_mrqa_question_generation
|
fs_opt
|
Detailed Instructions: Given a context passage, generate a question from the passage such that its answer is shortest continous span from the passage.
See one example below:
Problem: In 1582 the united provinces invited francis, duke of anjou to lead them; but after a failed attempt to take antwerp in 1583, the duke left the netherlands again. after the assassination of william of orange (10 july 1584), both henry iii of france and elizabeth i of england declined the offer of sovereignty. however, the latter agreed to turn the united provinces into a protectorate of england (treaty of nonsuch, 1585), and sent the earl of leicester as governor-general. this was unsuccessful and in 1588 the provinces became a confederacy. the union of utrecht is regarded as the foundation of the republic of the seven united provinces, which was not recognized by the spanish empire until the peace of westphalia in 1648.
Solution: In what year did francis, duke of anjou leave the netherlands?
Explanation: The generated question is perfect. Because the question is based on second sentence of the input passage and its answer is 1583.
Problem: How well soil forms and what type of soil forms depends on several different factors, which are described below. Scientists know that climate is the most important factor determining soil type because, given enough time, different rock types in a given climate will produce a similar soil (Figure 1.1). Even the same rock type in different climates will not produce the same type of soil. This is true because most rocks on Earth are made of the same eight elements and when the rock breaks down to become soil, those elements dominate. The same factors that lead to increased weathering also lead to greater soil formation. More rain equals more chemical reactions to weather minerals and rocks. Those reactions are most efficient in the top layers of the soil, where the water is fresh and has not yet reacted with other materials. Increased rainfall increases the amount of rock that is dissolved as well as the amount of material that is carried away by moving water. As materials are carried away, new surfaces are exposed, which also increases the rate of weathering. Climate is the most important factor in determining the type of soil that will form in a particular area. Increased temperature increases the rate of chemical reactions, which also increases soil formation. In warmer regions, plants and bacteria grow faster, which helps to weather material and produce soils. In tropical regions, where temperature and precipitation are consistently high, thick soils form. Arid regions have thin soils. Soil type also influences the type of vegetation that can grow in the region. We can identify climate types by the types of plants that grow there. The original rock is the source of the inorganic portion of the soil. The minerals that are present in the rock determine the composition of the material that is available to make soil. Soils may form in place or from material that has been moved. Residual soils form in place. The underlying rock breaks down to form the layers of soil that reside above it. Only about one-third of the soils in the United States are residual. Transported soils have been transported in from somewhere else. Sediments can be transported into an area by glaciers, wind, water, or gravity. Soils form from the loose particles that have been transported to a new location and deposited. The steeper the slope, the less likely material will be able to stay in place to form soil. Material on a steep slope is likely to go downhill. Materials will accumulate and soil will form where land areas are flat or gently undulating. Soils thicken as the amount of time available for weathering increases. The longer the amount of time that soil remains in a particular area, the greater the degree of alteration. The partial decay of plant material and animal remains produces the organic material and nutrients in soil. In soil, decomposing organisms breakdown the complex organic molecules of plant matter and animal remains to form simpler inorganic molecules that are soluble in water. Decomposing organisms also create organic acids that increase the rate of weathering and soil formation. Bacteria in the soil change atmospheric nitrogen into nitrates. The decayed remains of plant and animal life are called humus, which is an extremely important part of the soil. Humus coats the mineral grains. It binds them together into clumps that then hold the soil together, creating its structure. Humus increases the soils porosity and water-holding capacity and helps to buffer rapid changes in soil acidity. Humus also helps the soil to hold its nutrients, increasing its fertility. Fertile soils are rich in nitrogen, contain a high percentage of organic materials, and are usually black or dark brown in color. Soils that are nitrogen poor and low in organic material might be gray or yellow or even red in color. Fertile soils are more easily cultivated. Click image to the left or use the URL below. URL:
Solution:
|
what type of climate produces the thickest soils?
| 4
|
NIv2
|
task470_mrqa_question_generation
|
fs_opt
|
Part 1. Definition
Given a context passage, generate a question from the passage such that its answer is shortest continous span from the passage.
Part 2. Example
In 1582 the united provinces invited francis, duke of anjou to lead them; but after a failed attempt to take antwerp in 1583, the duke left the netherlands again. after the assassination of william of orange (10 july 1584), both henry iii of france and elizabeth i of england declined the offer of sovereignty. however, the latter agreed to turn the united provinces into a protectorate of england (treaty of nonsuch, 1585), and sent the earl of leicester as governor-general. this was unsuccessful and in 1588 the provinces became a confederacy. the union of utrecht is regarded as the foundation of the republic of the seven united provinces, which was not recognized by the spanish empire until the peace of westphalia in 1648.
Answer: In what year did francis, duke of anjou leave the netherlands?
Explanation: The generated question is perfect. Because the question is based on second sentence of the input passage and its answer is 1583.
Part 3. Exercise
On March 26, 2008, Ludia (in connection with Ubisoft) launched The Price Is Right video game for PC. A version for the Wii and Nintendo DS platforms was released in September 2008, while a version for the iOS (Apple) was released in November 2008. The shows announcer, Fields, was the host of the computer version. The virtual set in the game resembles the set used in seasons 31 to 34. Ludia announced that all three platforms will receive a new version of the video game that was previewed at the Target Bullseye Lounge during the Electronic Entertainment Expo trade show on June 2-4, 2009. The Price Is Right 2010 Edition was released on September 22, 2009. In the fall of 2010, Ludia developed a multi-player version for Facebook. A third Ludia adaptation, The Price Is Right Decades, featuring set designs, pricing games and prizes taken from the 1970s through 2000s; was initially released for the Wii in October 2011, with an Xbox 360 and iOS release following in November and December. The Price Is Right 2010 Edition and The Price Is Right Decades have also been released as downloads within the PlayStation Store for the PlayStation 3 in May 2010 and April 2012, respectively. Irwin Toys released an electronic tabletop version in 2008 featuring Contestants Row, the Big Wheel, a physical Plinko board with chips, Showcases and seven pricing games. Jakks Pacific released a Plug It in & Play TV Games version of The Price Is Right in 2009, featuring Carey and Fields.
Answer:
|
For which game did Xbox 360 receive a release before iOS?
| 7
|
NIv2
|
task470_mrqa_question_generation
|
fs_opt
|
Detailed Instructions: Given a context passage, generate a question from the passage such that its answer is shortest continous span from the passage.
See one example below:
Problem: In 1582 the united provinces invited francis, duke of anjou to lead them; but after a failed attempt to take antwerp in 1583, the duke left the netherlands again. after the assassination of william of orange (10 july 1584), both henry iii of france and elizabeth i of england declined the offer of sovereignty. however, the latter agreed to turn the united provinces into a protectorate of england (treaty of nonsuch, 1585), and sent the earl of leicester as governor-general. this was unsuccessful and in 1588 the provinces became a confederacy. the union of utrecht is regarded as the foundation of the republic of the seven united provinces, which was not recognized by the spanish empire until the peace of westphalia in 1648.
Solution: In what year did francis, duke of anjou leave the netherlands?
Explanation: The generated question is perfect. Because the question is based on second sentence of the input passage and its answer is 1583.
Problem: Set in the Australian outback in the 1880s, the movie follows the series of events following the horrific rape and murder of the Hopkins family, allegedly committed by the infamous Burns brothers gang.The film opens in a brothel during a violent gunfight between the police and Charlie Burns' (Guy Pearce) gang, which ends with the deaths of all of the gang members except for Charlie and his younger brother Mikey. Captain Stanley (Ray Winstone) proposes to Charlie: he and Mikey can go free of the crimes they have committed if Charlie kills his older brother, Arthur (Danny Huston). Arthur is a mercurial psychopath who has become something of a legend and is so vicious that the Aboriginal tribes refer to him as "The Dog Man" and both the police and the Aboriginals refuse to go near his camp. Captain Stanley muses that perhaps the bounty hunters will kill Arthur in time and then states his intention to civilize the harsh Australian wilderness by bringing Arthur to justice and using Mikey as leverage. Charlie has nine days to find and kill Arthur, or else Mikey will be hanged from the gallows on Christmas Day.We discover why Captain Stanley is intent on taming Australia: he has been forced to move there with his delicate wife, Martha Stanley (Emily Watson), and apparently wants to make it an appropriate place for them to live. The Stanleys were also friends of the Hopkins family, leading Martha to have nightmares about her dead friends and the unborn child one of them is revealed to have carried. Word spreads of Stanley's deal with Charlie, primarily from Stanley's corrupt subordinate, Sergeant Lawrence (Robert Morgan), causing disgust among the townspeople.Shortly thereafter, Eden Fletcher (David Wenham), for whom Captain Stanley works, orders that Mikey be given one hundred lashes as punishment for the rape and murder of the Hopkins family. Stanley is aghast at this, not only because he believes that Mikey is innocent and the flogging will surely kill him, but because it would also break his deal with Charlie and thus put him and his wife in grave danger. Stanley sends Sergeant Lawrence away with tracker Jacko (David Gulpillil) and other men to "investigate" the reported slaying of Dan O'Riley by a group of Aborigines. Captain Stanley attempts to defend Mikey by gunpoint from the bloodthirsty townspeople, but is overruled once Martha arrives, insisting on revenge for her dead friends. Mikey is then brutally flogged, and horrifically wounded. The formerly excited townspeople slowly become disgusted and Martha faints at the ghastly display. After 40 lashes, Mikey has collapsed and the whip is soaked with blood. Captain Stanley grabs the whip and throws it at Fletcher, staining his face and suit with blood, who in turn fires Stanley.Meanwhile, Charlie rides a great distance in search of Arthur, drinking and apparently reflecting on what he will do. Along the way, he encounters an inebriated old man named Jellon Lamb (John Hurt). In the course of conversation, Charlie realizes that Lamb is a bounty hunter in pursuit of the Burns brothers and knocks him out. Later on, after sleeping on a rock bed, Charlie awakes and, before he can gather what's going on, is speared in the chest by a group of Aboriginal men standing over him. Seconds later a gunshot is heard and the head of the man who threw the spear explodes. Charlie then passes out.Charlie wakes up in the camp of his brother Arthur, which is located in caves among desolate mountains. Arthur's gang consists of Samuel Stoat (Tom Budge), who shot the Aboriginal man who had speared Charlie; a woman named Queenie (Leah Purcell) who tends to Charlie's wound; and a muscular Aboriginal man called Two-Bob (Tom E. Lewis). As he recovers from his wounds, Charlie has several opportunities to kill his brother, but does not. Not too far away from Arthur's camp, Sergeant Lawrence and his men have found and butchered a group of Aborigines. Arthur and Two-Bob find Lawrence's group while they sleep, ostensibly to get a horse for Charlie, and proceed to kill Jacko and Sergeant Lawrence. Before Arthur stomps Lawrence
Solution:
|
Who plays Samuel Stoat?
| 4
|
NIv2
|
task470_mrqa_question_generation
|
fs_opt
|
Given a context passage, generate a question from the passage such that its answer is shortest continous span from the passage.
One example: In 1582 the united provinces invited francis, duke of anjou to lead them; but after a failed attempt to take antwerp in 1583, the duke left the netherlands again. after the assassination of william of orange (10 july 1584), both henry iii of france and elizabeth i of england declined the offer of sovereignty. however, the latter agreed to turn the united provinces into a protectorate of england (treaty of nonsuch, 1585), and sent the earl of leicester as governor-general. this was unsuccessful and in 1588 the provinces became a confederacy. the union of utrecht is regarded as the foundation of the republic of the seven united provinces, which was not recognized by the spanish empire until the peace of westphalia in 1648.
Solution is here: In what year did francis, duke of anjou leave the netherlands?
Explanation: The generated question is perfect. Because the question is based on second sentence of the input passage and its answer is 1583.
Now, solve this: It's time to be water efficient! As populations increase across Australia and the rest of the world, demand for water will also increase. If we don't reduce each individual's demand for water (both directly and through embodied water) the water situation will become dire. It is obvious that we cannot increase demands for water much more without detrimental effects to the environment, society and the economy. It's all too easy to blame someone else for the water situation -"if 70% of water is used for agriculture then that's what we should target" - but it's not that easy. We all depend on the food and resources that agriculture provides, and while there are definitely opportunities to increase water efficiency on the farm, the solution will take more than that. We each share responsibility for the sustainable management of our water resources, which means using less water at home, in the workplace, at school, on holidays, on the farm, ... everyone, everywhere, every time. It's time to become water efficient! This involves reassessing our relationship with water, and learning to use it more sparingly. On the most basic level, it requires a behavioural change, and assigning a value to water that truly reflects its worth. We can also unlock economic benefits of being water efficient. There are many real world examples given in the case studies on this site. Everybody has a responsibility to save water, if future generations are to enjoy a similar standard of living to the one we enjoy now. In fact, many of the impacts associated with water use are likely to have an effect on our own lives! www.savewater.com.au has been designed to help you respond to the challenge to become water efficient. It acts as a central repository for relevant information and further advice, so that you can actually achieve significant savings. It also showcases those companies with products that will assist you in your goal.
Solution:
|
What is the main idea of this passage?
| 6
|
NIv2
|
task470_mrqa_question_generation
|
fs_opt
|
You will be given a definition of a task first, then an example. Follow the example to solve a new instance of the task.
Given a context passage, generate a question from the passage such that its answer is shortest continous span from the passage.
In 1582 the united provinces invited francis, duke of anjou to lead them; but after a failed attempt to take antwerp in 1583, the duke left the netherlands again. after the assassination of william of orange (10 july 1584), both henry iii of france and elizabeth i of england declined the offer of sovereignty. however, the latter agreed to turn the united provinces into a protectorate of england (treaty of nonsuch, 1585), and sent the earl of leicester as governor-general. this was unsuccessful and in 1588 the provinces became a confederacy. the union of utrecht is regarded as the foundation of the republic of the seven united provinces, which was not recognized by the spanish empire until the peace of westphalia in 1648.
Solution: In what year did francis, duke of anjou leave the netherlands?
Why? The generated question is perfect. Because the question is based on second sentence of the input passage and its answer is 1583.
New input: 1836 Komarov, provisional designation 1971 OT, is a main-belt asteroid discovered on 26 July 1971 by Nikolai Chernykh at the Crimean Astrophysical Observatory in Nauchnyj.
Solution:
|
When was 1836 Komarov first discovered?
| 0
|
NIv2
|
task470_mrqa_question_generation
|
fs_opt
|
instruction:
Given a context passage, generate a question from the passage such that its answer is shortest continous span from the passage.
question:
Sandford-on-Thames is a village and Parish Council beside the River Thames in Oxfordshire just south of Oxford.
answer:
Which is the body of water by Sandford-on-Thames?
question:
Finally, in 2001, SV Nord-Nordstern and SC Wedding-Rapide came together to form SV Nord Wedding 1893.
answer:
What year did SV Nord Wedding 1893 dissolve?
question:
Set in the Australian outback in the 1880s, the movie follows the series of events following the horrific rape and murder of the Hopkins family, allegedly committed by the infamous Burns brothers gang.The film opens in a brothel during a violent gunfight between the police and Charlie Burns' (Guy Pearce) gang, which ends with the deaths of all of the gang members except for Charlie and his younger brother Mikey. Captain Stanley (Ray Winstone) proposes to Charlie: he and Mikey can go free of the crimes they have committed if Charlie kills his older brother, Arthur (Danny Huston). Arthur is a mercurial psychopath who has become something of a legend and is so vicious that the Aboriginal tribes refer to him as "The Dog Man" and both the police and the Aboriginals refuse to go near his camp. Captain Stanley muses that perhaps the bounty hunters will kill Arthur in time and then states his intention to civilize the harsh Australian wilderness by bringing Arthur to justice and using Mikey as leverage. Charlie has nine days to find and kill Arthur, or else Mikey will be hanged from the gallows on Christmas Day.We discover why Captain Stanley is intent on taming Australia: he has been forced to move there with his delicate wife, Martha Stanley (Emily Watson), and apparently wants to make it an appropriate place for them to live. The Stanleys were also friends of the Hopkins family, leading Martha to have nightmares about her dead friends and the unborn child one of them is revealed to have carried. Word spreads of Stanley's deal with Charlie, primarily from Stanley's corrupt subordinate, Sergeant Lawrence (Robert Morgan), causing disgust among the townspeople.Shortly thereafter, Eden Fletcher (David Wenham), for whom Captain Stanley works, orders that Mikey be given one hundred lashes as punishment for the rape and murder of the Hopkins family. Stanley is aghast at this, not only because he believes that Mikey is innocent and the flogging will surely kill him, but because it would also break his deal with Charlie and thus put him and his wife in grave danger. Stanley sends Sergeant Lawrence away with tracker Jacko (David Gulpillil) and other men to "investigate" the reported slaying of Dan O'Riley by a group of Aborigines. Captain Stanley attempts to defend Mikey by gunpoint from the bloodthirsty townspeople, but is overruled once Martha arrives, insisting on revenge for her dead friends. Mikey is then brutally flogged, and horrifically wounded. The formerly excited townspeople slowly become disgusted and Martha faints at the ghastly display. After 40 lashes, Mikey has collapsed and the whip is soaked with blood. Captain Stanley grabs the whip and throws it at Fletcher, staining his face and suit with blood, who in turn fires Stanley.Meanwhile, Charlie rides a great distance in search of Arthur, drinking and apparently reflecting on what he will do. Along the way, he encounters an inebriated old man named Jellon Lamb (John Hurt). In the course of conversation, Charlie realizes that Lamb is a bounty hunter in pursuit of the Burns brothers and knocks him out. Later on, after sleeping on a rock bed, Charlie awakes and, before he can gather what's going on, is speared in the chest by a group of Aboriginal men standing over him. Seconds later a gunshot is heard and the head of the man who threw the spear explodes. Charlie then passes out.Charlie wakes up in the camp of his brother Arthur, which is located in caves among desolate mountains. Arthur's gang consists of Samuel Stoat (Tom Budge), who shot the Aboriginal man who had speared Charlie; a woman named Queenie (Leah Purcell) who tends to Charlie's wound; and a muscular Aboriginal man called Two-Bob (Tom E. Lewis). As he recovers from his wounds, Charlie has several opportunities to kill his brother, but does not. Not too far away from Arthur's camp, Sergeant Lawrence and his men have found and butchered a group of Aborigines. Arthur and Two-Bob find Lawrence's group while they sleep, ostensibly to get a horse for Charlie, and proceed to kill Jacko and Sergeant Lawrence. Before Arthur stomps Lawrence
answer:
|
Who plays Samuel Stoat?
| 9
|
NIv2
|
task470_mrqa_question_generation
|
fs_opt
|
Teacher: Given a context passage, generate a question from the passage such that its answer is shortest continous span from the passage.
Teacher: Now, understand the problem? If you are still confused, see the following example:
In 1582 the united provinces invited francis, duke of anjou to lead them; but after a failed attempt to take antwerp in 1583, the duke left the netherlands again. after the assassination of william of orange (10 july 1584), both henry iii of france and elizabeth i of england declined the offer of sovereignty. however, the latter agreed to turn the united provinces into a protectorate of england (treaty of nonsuch, 1585), and sent the earl of leicester as governor-general. this was unsuccessful and in 1588 the provinces became a confederacy. the union of utrecht is regarded as the foundation of the republic of the seven united provinces, which was not recognized by the spanish empire until the peace of westphalia in 1648.
Solution: In what year did francis, duke of anjou leave the netherlands?
Reason: The generated question is perfect. Because the question is based on second sentence of the input passage and its answer is 1583.
Now, solve this instance: The susceptibility to arbekacin (ABK) of methicillin-resistant Staphylococcus aureus (MRSA) was investigated to find out how it related to aac(6')/aph(2") gene. In 49 isolates of MRSA for which MIC of ABK ranged from 0.125 to 64 micrograms/ml, the MICs of ABK for 38 strains carrying aac(6')/aph(2") gene were widely distributed from 0.25 to 64, whereas those for 11 strains without that gene were all < or = 0.5 microgram/ml. Residual rate of ABK activity was higher than that of gentamicin after the reaction with each crude enzyme preparation extracted from 3 isolates of MRSA, carrying aac(6')/aph(2") and aad(4',4") genes. Furthermore, 97 strains of MRSA isolated at Kanagawa prefecture in Japan in 1999 were all sensitive to ABK, although 28 strains of them carried aac(6')/aph(2") gene. These results showed that ABK resistance was not necessarily related to carrying aac(6')/aph(2") gene in clinical isolates of MRSA.
Student:
|
What is MRSA?
| 2
|
NIv2
|
task470_mrqa_question_generation
|
fs_opt
|
Given the task definition, example input & output, solve the new input case.
Given a context passage, generate a question from the passage such that its answer is shortest continous span from the passage.
Example: In 1582 the united provinces invited francis, duke of anjou to lead them; but after a failed attempt to take antwerp in 1583, the duke left the netherlands again. after the assassination of william of orange (10 july 1584), both henry iii of france and elizabeth i of england declined the offer of sovereignty. however, the latter agreed to turn the united provinces into a protectorate of england (treaty of nonsuch, 1585), and sent the earl of leicester as governor-general. this was unsuccessful and in 1588 the provinces became a confederacy. the union of utrecht is regarded as the foundation of the republic of the seven united provinces, which was not recognized by the spanish empire until the peace of westphalia in 1648.
Output: In what year did francis, duke of anjou leave the netherlands?
The generated question is perfect. Because the question is based on second sentence of the input passage and its answer is 1583.
New input case for you: From 2007 until 2012, the Pentagon's MRAP program deployed more than 12,000 MRAPs in the Iraq War and War in Afghanistan.
Output:
|
What was the year that MRAP entered service?
| 1
|
NIv2
|
task470_mrqa_question_generation
|
fs_opt
|
Given a context passage, generate a question from the passage such that its answer is shortest continous span from the passage.
Let me give you an example: In 1582 the united provinces invited francis, duke of anjou to lead them; but after a failed attempt to take antwerp in 1583, the duke left the netherlands again. after the assassination of william of orange (10 july 1584), both henry iii of france and elizabeth i of england declined the offer of sovereignty. however, the latter agreed to turn the united provinces into a protectorate of england (treaty of nonsuch, 1585), and sent the earl of leicester as governor-general. this was unsuccessful and in 1588 the provinces became a confederacy. the union of utrecht is regarded as the foundation of the republic of the seven united provinces, which was not recognized by the spanish empire until the peace of westphalia in 1648.
The answer to this example can be: In what year did francis, duke of anjou leave the netherlands?
Here is why: The generated question is perfect. Because the question is based on second sentence of the input passage and its answer is 1583.
OK. solve this:
As Tsushima had suffered greatly from its loss of trade with Korea as a result of the invasions, Yoshitoshi of the So family, then dominant in Tsushima, undertook the lead in the peace negotiations by Japan. He sent four peace missions to Joseon in 1599 to normalize relations. The first three were captured and sent directly to Beijing by Chinese troops, but the fourth one, in 1601, successfully obtained from the Joseon court the promise of a normalizing of relations upon the return of remaining Joseon captives. As Ming troops continued to be present in Korea following the withdrawal of Japanese forces, the major incentive for Joseon for the normalization of relations with Japan was the withdrawal of the Chinese soldiers from their territory. The Ming Chinese themselves were causing as much havoc as the Japanese had during the actual conflict, and their presence continued to strain Joseon's national economy and infrastructure. In response to the Joseon request, Yoshitoshi promptly released several Joseon prisoners and between 1603 and 1604 helped the Joseon envoys to repatriate a further 3,000 by organizing negotiations at Kyoto with Tokugawa Ieyasu, by then the Shogun of Japan. In the continuation of the diplomatic talks toward peaceful relations, Joseon in 1606 expanded its conditions and demanded that the Shogun write a formal letter requesting peace, and to extradite the Japanese soldiers who had defiled the Joseon Royal Tombs near Hanseong . Realizing that the Shogunate would never agree to such a request, Yoshitoshi sent a forged letter and a group of criminals instead; the great need to expel the Ming soldiers pushed Joseon into accepting and to send an emissary in 1608. The end result was a return of Joseon prisoners and the restoration of diplomatic and trade relations between the two countries.
Answer:
|
Who sent four peace missions to Joseon in 1599?
| 8
|
NIv2
|
task470_mrqa_question_generation
|
fs_opt
|
Given a context passage, generate a question from the passage such that its answer is shortest continous span from the passage.
Example: In 1582 the united provinces invited francis, duke of anjou to lead them; but after a failed attempt to take antwerp in 1583, the duke left the netherlands again. after the assassination of william of orange (10 july 1584), both henry iii of france and elizabeth i of england declined the offer of sovereignty. however, the latter agreed to turn the united provinces into a protectorate of england (treaty of nonsuch, 1585), and sent the earl of leicester as governor-general. this was unsuccessful and in 1588 the provinces became a confederacy. the union of utrecht is regarded as the foundation of the republic of the seven united provinces, which was not recognized by the spanish empire until the peace of westphalia in 1648.
Example solution: In what year did francis, duke of anjou leave the netherlands?
Example explanation: The generated question is perfect. Because the question is based on second sentence of the input passage and its answer is 1583.
Problem: The Local Stigmatic is based on a stage play by Heathcote Williams.
|
Solution: In which The Local Stigmatic a 1909 american silent drama film directed by?
| 5
|
NIv2
|
task470_mrqa_question_generation
|
fs_opt
|
Given a context passage, generate a question from the passage such that its answer is shortest continous span from the passage.
Q: Phoebe Campbell (c. 1847 -- 20 June 1872) was a Canadian woman who was hanged for the murder of her husband.
A: Which crime Phoebe Campbell is considered to have commited?
****
Q: Lewy bodies and coarse Lewy neurites are the pathological hallmarks of degenerating neurons in the brains of patients suffering from Parkinson's disease (PD). Recently, the presynaptic protein alpha-synuclein was shown to be a major component of Lewy bodies and Lewy neurites. This study demonstrates for the first time that extensive and thin alpha-synuclein-immunoreactive inclusions are present in the axonal processes of neurons.
A: Which is the primary protein component of Lewy bodies?
****
Q: The Local Stigmatic is based on a stage play by Heathcote Williams.
A:
|
In which The Local Stigmatic a 1909 american silent drama film directed by?
****
| 4
|
NIv2
|
task470_mrqa_question_generation
|
fs_opt
|
TASK DEFINITION: Given a context passage, generate a question from the passage such that its answer is shortest continous span from the passage.
PROBLEM: Luka orevic (Cyrillic: a , born 9 July 1994) is a Montenegrin footballer who plays as a forward for Spanish club SD Ponferradina on loan from FC Zenit Saint Petersburg.
SOLUTION: The birth date of Luka Đorđević is what?
PROBLEM: "We don't necessarily believe that new advertising, which might make consumers feel better about the Coke brand or better about the ads themselves , will actually result in consumers consuming more of the product," Morgan Stanley's Bill Pecoriello wrote in a research note the days after the investor meeting . But Coke is optimistic it can regain its old magic, and is banking on a new slogan: "Welcome to the Coke side of life." BREAK THROUGH HIT? With PepsiCo about to surpass Coke as the beverage king on Wall Street--Pepsi's market capitalization has _ in recent years to $97.9 billion, putting it less than a billion dollars behind its rival--the heat is on Coke . It's set to launch a new marketing campaign in March, 2006. And having taken a quick look at Coke's investor presentation on Dec. 7 in New York, my sense is that Coke may be moving in the right direction . Given the continued shift by consumers away from soda--Coke's stronghold --and into alternative beverages like juice, tea, and water, Coke badly needs a breakthrough hit. And given that shift away from soda, some analyists wonder whether even the catchiest new ads will be enough to put the fizz back into Coke. SAME OLD, UPDATED? The new flavors of PowerAde sports drink will probably enable Coke to continue stealing market share from PepsiCo's Gatorade brand. And Coke is getting a little more creative with packaging, including new, aluminum bottles of Coke that will be sold in nightclubs, and an 8.4-ounce "100 calorie" version of its flagship Coke that will appeal to women who want fewer calories and will like the fact that the small can will fit in their purse. I doubt whether other new products will be successful, including a new coffee-flavored soda called Coke-Cola Black that I tried. Think carbonated coffee. But I'm not sure if the product, which Coke is pitching as an afternoon pick-me-up for the 35-and-over set, is going to pull people away from their afternoon Frappucino fix. And my opinion is that Vault, an orange-flavored energy drink, will have just as much trouble unseating Mountain Dew among teens as did Coke's last attempt, a product called Surge. If there is one concern I have about the fresh offerings Coke plans to launch this year, it appears that many of them are simply new brands, not new products.
SOLUTION: When the middle-aged people feel tired, what would they prefer to drink in order to continue their work?
PROBLEM: Ptolemy III Euergetes (Greek: , Ptolemaios Euergetes, reigned 246--222 BC) was the third king of the Ptolemaic dynasty in Egypt.
SOLUTION:
|
What family lineage was Ptolemy III Euergetes part of?
| 8
|
NIv2
|
task470_mrqa_question_generation
|
fs_opt
|
Given a context passage, generate a question from the passage such that its answer is shortest continous span from the passage.
[EX Q]: If you wish to become a better reader, here are four important things to remember about reading _ : * Knowing why you are reading or what you are reading to find out will often help you to know whether to read rapidly or slowly. * Some things should be read slowly throughout. Examples are directions for making or doing something, arithmetic problems, science and history books, which are full of important information. You must read such things slowly to remember each important step and understand each important ideas. * Some things should be read rapidly throughout. Examples are simple stories meant for enjoyment, news letters from friends, pieces of news from local, or home-town, papers, telling what is happening to friends and neighbors. * In some of your reading, you must change your speed from fast to slow and slow to fast, as you go along. You will need to read certain pages rapidly and then slow down and do more careful reading when you come to important ideas which must be remembered.
[EX A]: Which should be read slowly according to the passage?
[EX Q]: Cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL) is a small vessel disease of the brain caused by mutations in the NOTCH3 gene. CADASIL progresses, in some cases, to subcortical dementia with a particular cognitive impairment. Different diseases in the dementia spectrum share a central cholinergic and sensorimotor plasticity alteration. We aimed to study different intracortical circuits and sensorimotor plasticity in CADASIL patients using transcranial magnetic stimulation protocols, and to determine whether these characteristics correlated with the results of clinical neuropsychological evaluation. Ten CADASIL patients and 10 healthy subjects were included in the study. All subjects underwent a transcranial magnetic stimulation study examining different intracortical circuits. Sensorimotor plasticity was also assessed using a paired associative stimulation and extensive neuropsychological tests. CADASIL patients showed a lack of intracortical facilitation, short latency afferent inhibition and sensorimotor plasticity when compared with control subjects. CADASIL patients also showed an altered neuropsychological profile. Correlation between sensorimotor plasticity and neuropsychological alterations was observed in CADASIL patients. These results suggest that acetylcholine and glutamate could be involved in the dementia process in CADASIL and that abnormal sensorimotor plasticity correlates with the neuropsychological profile in CADASIL patients.
[EX A]: Which gene is involved in CADASIL?
[EX Q]: HD 27245 is a variable red giant star in the northern constellation of Camelopardalis.
[EX A]:
|
What constellation is HD 27245 in?
| 6
|
NIv2
|
task470_mrqa_question_generation
|
fs_opt
|
Given a context passage, generate a question from the passage such that its answer is shortest continous span from the passage.
Input: Consider Input: Coming off their last-second victory over the Bengals, the Broncos would play their Week 2 home opener against the Cleveland Browns. In the first quarter, Denver would trail early as Browns kicker Phil Dawson got a 22-yard field goal. Afterwards, the Broncos took the lead as quarterback Kyle Orton completed a 2-yard touchdown pass to tight end Tony Scheffler. Cleveland would creep close as Dawson made a 47-yard field goal, but Denver would answer as kicker Matt Prater got a 23-yard field goal in the second quarter and a 38-yard field goal in the third quarter. In the fourth, the Broncos pulled away as fullback Peyton Hillis got a 2-yard touchdown run and running back Correll Buckhalter got a 45-yard touchdown run.
Output: Which player kicked the second longest field goal?
Input: Consider Input: CADASIL is a cerebrovascular disease caused by mutations in the NOTCH3 gene. Most mutations result in a gain or loss of cysteine residue in one of the 34 epidermal growth factor-like repeats in the extracellular domain of the Notch3 protein, thus sparing the number of cysteine residues. To date, more than 130 different mutations in the NOTCH3 gene have been reported in CADASIL patients, of which 95% are missense point mutations. Many polymorphisms have also been identified in the NOTCH3 coding sequence, some of them leading to amino acid substitutions. The aim of the present study was to analyze the NOTCH3 gene in a large group of patients affected by leukoencephalopathy and to investigate the presence of genetic variants. The molecular analysis revealed several nucleotide alterations. In particular, we identified 20 different mutations, 22 polymorphisms, and 8 genetic variants of unknown pathological significance never reported previously. We hope that this NOTCH3 gene mutational analysis, performed in such a significant number of unrelated and related patients affected by leukoencephalopathy, will help in molecular screening for the NOTCH3 gene, thus contributing to enlargement of the NOTCH3 gene variation database.
Output: Which amino acid residue appears mutated in most of the cases reported with cadasil syndrome?
Input: Consider Input: The Seattle Seahawks kicked off their 2013 campaign with a hard-fought, ugly win over the Carolina Panthers, 12-7. This game marked Russell Wilson's first 300-yard passing game, and Cam Newton's worst career performance, posting 125 yards through the air, a career low. The first quarter ended equal for both teams, as both sides exchanged a couple of punts. Seattle took their third drive of the game in the second quarter, and drove into the red zone, capping it with a Steven Hauschka 27-yard field goal. Carolina responded immediately, and taking advantage of a couple of Seattle penalties, and some big runs by DeAngelo Williams, with Cam Newton hitting Steve Smith for a 3-yard TD. Seattle responded with a drive to around the Carolina 27 yard line, but Charles Godfrey sacked Russell Wilson and stripped the football, which Carolina recovered. So the first half ended 7-3, Carolina. The second half began with a defensive battle between both sides. Seattle then broke the deadlock with a Steven Hauschka 40-yard field goal, on a drive that lasted over 4 minutes, cutting the lead to 7-6. After forcing Carolina to punt midway through the fourth quarter, Seattle's offense produced its finest drive of the day. A couple of Russell Wilson passes, followed by a Robert Turbin 15-yard scamper, set up Seattle at the Panthers' 43 yard line. Russell Wilson overthrew receiver Stephen Williams on first down, but on second down and 10, by using exactly the same play, Wilson connected with second-year man Jermaine Kearse for a 43-yard score, with 10 minutes left to play. They failed the two-point conversion however, so Seattle had a 12-7 lead. Carolina responded by using DeAngelo Williams on some big runs. Inside the Seattle 35 yard line, Williams took off for a 24-yard scamper, and looked like he was going to score, however at the last possible moment, Earl Thomas forced Williams to fumble inside the 10 yard line.
|
Output: Who threw for more yards, Wilson or Newton?
| 2
|
NIv2
|
task470_mrqa_question_generation
|
fs_opt
|
Given a context passage, generate a question from the passage such that its answer is shortest continous span from the passage.
Ex Input:
Mercury is released into the atmosphere when coal is burned (Figure 1.1). But breathing the mercury is not harmful. In the atmosphere, the mercury forms small droplets that are deposited in water or sediments. Do you know why you are supposed to eat large predatory fish like tuna infrequently? It is because of the bioaccu- mulation of mercury in those species. Some pollutants remain in an organism throughout its life, a phenomenon called bioaccumulation. In this process, an organism accumulates the entire amount of a toxic compound that it consumes over its lifetime. Not all substances bioaccumulate. Can you name one that does not? Aspirin does not bioaccumulate; if it did, a person would quickly accumulate a toxic amount in her body. Compounds that bioaccumulate are usually stored in the organisms fat. In the sediments, bacteria convert the droplets to the hazardous compound methyl mercury. Bacteria and plankton store all of the mercury from all of the seawater they ingest (Figure 1.2). A small fish that eats bacteria and plankton accumulates all of the mercury from all of the tiny creatures it eats over its lifetime. A big fish accumulates all of the mercury from all of the small fish it eats over its lifetime. For a tuna at the top of the food chain, thats a lot of mercury. Historic increases of mercury in the atmo- sphere: blue is volcanic eruptions; brown, purple, and pink are human-caused. The red region shows the effect of industrial- ization on atmospheric mercury. So tuna pose a health hazard to anything that eats them because their bodies are so high in mercury. This is why the government recommends limits on the amount of tuna that people eat. Limiting intake of large predatory fish is especially important for children and pregnant women. If the mercury just stayed in a persons fat, it would not be harmful, but that fat is used when a woman is pregnant or nursing a baby. A person will also get the mercury into her system when she (or he) burns the fat while losing weight. Methyl mercury poisoning can cause nervous system or brain damage, especially in infants and children. Children may experience brain damage or developmental delays. The phrase mad as a hatter was common when Lewis Carroll wrote his Alice in Wonderland stories. It was based on symptoms suffered by hatters who were exposed to mercury and experienced mercury poisoning while using the metal to make hats (Figure 1.3). Like mercury, other metals and VOCS can bioaccumulate, causing harm to animals and people high on the food chain. Mercury, a potent neurotoxin, has been flowing into the San Francisco Bay since the Gold Rush Era. It has settled in the bays mud and made its way up the food chain, endangering wildlife and making many fish unsafe to eat. Now a multi-billion-dollar plan aims to clean it up. Click image to the left or use the URL below. URL:
Ex Output:
mercury poisoning can drive a person to be as mad as a hatter, which is based off of this novel.
Ex Input:
NASCAR Thunder 2002 is a racing simulator video game developed by EA Tiburon and published by EA Sports that came out for the Sony PlayStation, Sony PlayStation 2, and Xbox.
Ex Output:
Who worked on NASCAR Thunder 2002?
Ex Input:
The susceptibility to arbekacin (ABK) of methicillin-resistant Staphylococcus aureus (MRSA) was investigated to find out how it related to aac(6')/aph(2") gene. In 49 isolates of MRSA for which MIC of ABK ranged from 0.125 to 64 micrograms/ml, the MICs of ABK for 38 strains carrying aac(6')/aph(2") gene were widely distributed from 0.25 to 64, whereas those for 11 strains without that gene were all < or = 0.5 microgram/ml. Residual rate of ABK activity was higher than that of gentamicin after the reaction with each crude enzyme preparation extracted from 3 isolates of MRSA, carrying aac(6')/aph(2") and aad(4',4") genes. Furthermore, 97 strains of MRSA isolated at Kanagawa prefecture in Japan in 1999 were all sensitive to ABK, although 28 strains of them carried aac(6')/aph(2") gene. These results showed that ABK resistance was not necessarily related to carrying aac(6')/aph(2") gene in clinical isolates of MRSA.
Ex Output:
|
What is MRSA?
| 1
|
NIv2
|
task470_mrqa_question_generation
|
fs_opt
|
Given a context passage, generate a question from the passage such that its answer is shortest continous span from the passage.
Example input: In 1582 the united provinces invited francis, duke of anjou to lead them; but after a failed attempt to take antwerp in 1583, the duke left the netherlands again. after the assassination of william of orange (10 july 1584), both henry iii of france and elizabeth i of england declined the offer of sovereignty. however, the latter agreed to turn the united provinces into a protectorate of england (treaty of nonsuch, 1585), and sent the earl of leicester as governor-general. this was unsuccessful and in 1588 the provinces became a confederacy. the union of utrecht is regarded as the foundation of the republic of the seven united provinces, which was not recognized by the spanish empire until the peace of westphalia in 1648.
Example output: In what year did francis, duke of anjou leave the netherlands?
Example explanation: The generated question is perfect. Because the question is based on second sentence of the input passage and its answer is 1583.
Q: Individuals with Mowat-Wilson syndrome (MWS; OMIM#235730) have characteristic facial features, a variety of congenital anomalies such as Hirschsprung disease, and intellectual disabilities caused by mutation or deletion of ZEB2 gene. This deletion or cytogenetic abnormality has been reported primarily from Europe, Australia and the United States, but not in Korea. Here we report a patient with characteristic facial features of MWS, developmental delay and spasticity. High resolution microarray analysis revealed 0.9 Mb deletion of 2q22.3 involving two genes: ZEB2 and GTDC1. This case shows the important role of high resolution microarray in patients with unexplained psychomotor retardation and/or facial dysmorphism. Knowledge about the most striking clinical signs and implementation of effective molecular tests like microarray could significantly increase the detection rate of new cases of MWS in Korea. This is the first reported case of MWS in Korea.
A:
|
Which gene is responsible for the development of the Mowat-Wilson syndrome?
| 3
|
NIv2
|
task470_mrqa_question_generation
|
fs_opt
|
Given a context passage, generate a question from the passage such that its answer is shortest continous span from the passage.
One example: In 1582 the united provinces invited francis, duke of anjou to lead them; but after a failed attempt to take antwerp in 1583, the duke left the netherlands again. after the assassination of william of orange (10 july 1584), both henry iii of france and elizabeth i of england declined the offer of sovereignty. however, the latter agreed to turn the united provinces into a protectorate of england (treaty of nonsuch, 1585), and sent the earl of leicester as governor-general. this was unsuccessful and in 1588 the provinces became a confederacy. the union of utrecht is regarded as the foundation of the republic of the seven united provinces, which was not recognized by the spanish empire until the peace of westphalia in 1648.
Solution is here: In what year did francis, duke of anjou leave the netherlands?
Explanation: The generated question is perfect. Because the question is based on second sentence of the input passage and its answer is 1583.
Now, solve this: Britons spend as much as nearly five hours a week keeping their homes clean, a survey found. Kitchens are cleaned most often, while doing the oven and windows are the least popular jobs. In total, they spend just over PS1 billion a year on products to keep the dirt at bay -- almost PS40 per household. Market analyst Mintel found a clear division of labour. While the average Briton spends 4 hours, 40 minutes cleaning their home each week, men spend just 3 hours, 53 minutes compared to 5 hours, 25 minutes for women. And while seven in ten women say they do most of the cleaning, this falls to four in ten for men. Confirming many parents' feelings, only one in five adult children and over living at their parents' home helps with cleaning chores, with children under 18 doing even less. Last year, the household cleaning market was worth PS1.06 billion, which equates to annual spending of PS39.89 per household. Those looking for the cleanest homes in the country should head to Scotland, where people spend an average of five fours, 6 minutes, which is closely followed by East and West Midlands at five hours, 1 minute. In comparison, the least number of hours spent in cleaning is spent in the southeast/East Anglia at four hours, 18 minutes. The southwest and Wales stand at four hours, 46 minutes, the northwest four hours, 44 minutes, and Yorkshire and the Humber four hours, 21 minutes. According to Richard Caines, Mintel's senior household care analyst, men still lag women in the household cleaning stakes and spend on average an hour and a half less time cleaning their home, suggesting an opportunity for a campaign to encourage more cleaning by men to helpredressthis imbalance. The number of households that need cleaning is continuing to grow, but pressure on time from increasingly busy lives limits the number of hours people are willing or able to spend cleaning their homes. This means the market will see an increasing focus on easy-to-use, but effective hard surface cleaners and cleaning equipment. Such products can help encourage more cleaning to be done in less time, but as well as focusing on more convenient products, cleaning brands can also inject an element of fun into campaigns through encouraging a more shared approach that involves the whole family. This will also help to address the gender imbalance and get older children to make more of a contribution to cleaning.
Solution:
|
In which area do people spend the most time cleaning their home each week?
| 6
|
NIv2
|
task470_mrqa_question_generation
|
fs_opt
|
Given a context passage, generate a question from the passage such that its answer is shortest continous span from the passage.
Let me give you an example: In 1582 the united provinces invited francis, duke of anjou to lead them; but after a failed attempt to take antwerp in 1583, the duke left the netherlands again. after the assassination of william of orange (10 july 1584), both henry iii of france and elizabeth i of england declined the offer of sovereignty. however, the latter agreed to turn the united provinces into a protectorate of england (treaty of nonsuch, 1585), and sent the earl of leicester as governor-general. this was unsuccessful and in 1588 the provinces became a confederacy. the union of utrecht is regarded as the foundation of the republic of the seven united provinces, which was not recognized by the spanish empire until the peace of westphalia in 1648.
The answer to this example can be: In what year did francis, duke of anjou leave the netherlands?
Here is why: The generated question is perfect. Because the question is based on second sentence of the input passage and its answer is 1583.
OK. solve this:
The Jets' seventh game was an interconference duel with the Packers. Punter Steve Weatherford made the game's most controversial decision in the first quarter, opting to attempt a fake punt and run for the first down on 4th and 18. Weatherford was stopped a yard short of the first down, giving the Packers ideal field position which eventually led to an early 3-0 Packers lead. "He does it on his own," Ryan said. "(The Packers) were caving that side down. This was something Steve did on his own. I don't think he realized we'd just been sacked. We told him before that it needed to be a manageable situation, not fourth-and-20 or whatever it was.". In a game where defense ruled, the Packers lead 3-0 at halftime. The Jets challenged a Brad Smith fumble, and lost due to his knee not being down before losing the ball. However, the Jets second challenge went to a jump ball, called an interception after Packers cornerback Tramon Williams ripped the ball out of Jerricho Cotchery's hands while they were both on the ground. The play was controversially upheld, despite the fact that the receiver appeared to be down by contact. With no challenges left, Mark Sanchez threw a ball to Dustin Keller that was ripped out of his hands and ruled an interception in the 4th quarter. The replay showed that Keller made the catch and was also down before losing possession, but with no challenges left the Jets were left with nothing. Green Bay took a 6-0 lead after the turnover. The Jets had two more chances to take the lead but had drives halted on 4th and longs. The Packers added on another field goal late to finalize a 9-0 win in the New Meadowlands Stadium. This marked the first time since 2006 the Jets were shut out.
Answer:
|
Which team scored the least points?
| 8
|
NIv2
|
task470_mrqa_question_generation
|
fs_opt
|
Given a context passage, generate a question from the passage such that its answer is shortest continous span from the passage.
Example input: In 1582 the united provinces invited francis, duke of anjou to lead them; but after a failed attempt to take antwerp in 1583, the duke left the netherlands again. after the assassination of william of orange (10 july 1584), both henry iii of france and elizabeth i of england declined the offer of sovereignty. however, the latter agreed to turn the united provinces into a protectorate of england (treaty of nonsuch, 1585), and sent the earl of leicester as governor-general. this was unsuccessful and in 1588 the provinces became a confederacy. the union of utrecht is regarded as the foundation of the republic of the seven united provinces, which was not recognized by the spanish empire until the peace of westphalia in 1648.
Example output: In what year did francis, duke of anjou leave the netherlands?
Example explanation: The generated question is perfect. Because the question is based on second sentence of the input passage and its answer is 1583.
Q: Infectious Mononucleosis (IM), a benign lymphoproliferative disease, is the best known clinical syndrome caused by Epstein-Barr Virus (EBV). It usually resolves over a period of weeks or months without sequelae but may occasionally be complicated by a wide variety of neurologic, hematologic, hepatic, respiratory, and psychological complications. In this report we describe a patient with acute hepatitis following EBV-IM in a previously healthy woman. A 26-year-old woman who presented with fever, generalized weakness, nausea, sore throat, yellowing of skin, and a generalized skin rash was admitted to our clinic. Tonsillar enlargement, pharyngeal erythema, palatal petechiae, lymphadenopathy, and jaundice were noted. Significant atypical lymphocytes ( > 10%) were seen on the peripheral blood smear. Liver function tests such as ALT: 303 U/L, AST: 172 U/L, ALP: 193 U/L and total bilirubin: 7.3 mg/dl were elevated. Serological tests for EBV infection were consistent with acute infection (EBV virus capsid antigen was reactive with IgM and IgG antibodies). The Monospot test was also positive. On the seventh day, liver function tests and bilirubin had risen to peak level and platelets were decreased. The patient was managed supportively and her critical condition improved and was finally stabilized. Although the prognosis for IM is very favorable, a variety of acute complications may occur.
A:
|
Which virus can be diagnosed with the monospot test?
| 3
|
NIv2
|
task470_mrqa_question_generation
|
fs_opt
|
Given a context passage, generate a question from the passage such that its answer is shortest continous span from the passage.
Let me give you an example: In 1582 the united provinces invited francis, duke of anjou to lead them; but after a failed attempt to take antwerp in 1583, the duke left the netherlands again. after the assassination of william of orange (10 july 1584), both henry iii of france and elizabeth i of england declined the offer of sovereignty. however, the latter agreed to turn the united provinces into a protectorate of england (treaty of nonsuch, 1585), and sent the earl of leicester as governor-general. this was unsuccessful and in 1588 the provinces became a confederacy. the union of utrecht is regarded as the foundation of the republic of the seven united provinces, which was not recognized by the spanish empire until the peace of westphalia in 1648.
The answer to this example can be: In what year did francis, duke of anjou leave the netherlands?
Here is why: The generated question is perfect. Because the question is based on second sentence of the input passage and its answer is 1583.
OK. solve this:
The Seattle Seahawks kicked off their 2013 campaign with a hard-fought, ugly win over the Carolina Panthers, 12-7. This game marked Russell Wilson's first 300-yard passing game, and Cam Newton's worst career performance, posting 125 yards through the air, a career low. The first quarter ended equal for both teams, as both sides exchanged a couple of punts. Seattle took their third drive of the game in the second quarter, and drove into the red zone, capping it with a Steven Hauschka 27-yard field goal. Carolina responded immediately, and taking advantage of a couple of Seattle penalties, and some big runs by DeAngelo Williams, with Cam Newton hitting Steve Smith for a 3-yard TD. Seattle responded with a drive to around the Carolina 27 yard line, but Charles Godfrey sacked Russell Wilson and stripped the football, which Carolina recovered. So the first half ended 7-3, Carolina. The second half began with a defensive battle between both sides. Seattle then broke the deadlock with a Steven Hauschka 40-yard field goal, on a drive that lasted over 4 minutes, cutting the lead to 7-6. After forcing Carolina to punt midway through the fourth quarter, Seattle's offense produced its finest drive of the day. A couple of Russell Wilson passes, followed by a Robert Turbin 15-yard scamper, set up Seattle at the Panthers' 43 yard line. Russell Wilson overthrew receiver Stephen Williams on first down, but on second down and 10, by using exactly the same play, Wilson connected with second-year man Jermaine Kearse for a 43-yard score, with 10 minutes left to play. They failed the two-point conversion however, so Seattle had a 12-7 lead. Carolina responded by using DeAngelo Williams on some big runs. Inside the Seattle 35 yard line, Williams took off for a 24-yard scamper, and looked like he was going to score, however at the last possible moment, Earl Thomas forced Williams to fumble inside the 10 yard line.
Answer:
|
Who threw for more yards, Wilson or Newton?
| 8
|
NIv2
|
task470_mrqa_question_generation
|
fs_opt
|
TASK DEFINITION: Given a context passage, generate a question from the passage such that its answer is shortest continous span from the passage.
PROBLEM: In 1997 the Kymi Province was merged with the Uusimaa Province and the southern parts of the Hame Province into the new Southern Finland Province.
SOLUTION: What was replaced Kymi Province?
PROBLEM: Rigel Pharmaceuticals Inc is developing fostamatinib, a prodrug of the spleen tyrosine kinase (Syk) inhibitor R-406, for the potential treatment of autoimmune diseases such as rheumatoid arthritis (RA), idiopathic thrombocytopenic purpura (ITP) and B-cell lymphomas. Syk is a key mediator of Fc and B-cell receptor signaling in inflammatory cells, such as B-cells, mast cells, macrophages and neutrophils. Preclinical studies of R-406 or fostamatinib demonstrated a significant reduction in major inflammatory mediators such as TNFalpha, IL-1, IL-6 and IL-18, leading to reduced inflammation and bone degradation in models of RA. In a phase II clinical trial, fostamatinib treatment effectively improved American College of Rheumatology response rates in patients with RA. Preclinical studies and phase II trials also suggested the potential of using fostamatinib for the treatment of ITP and B-cell lymphomas, by increasing platelet counts and inducing response rates, respectively. Fostamatinib is orally bioavailable and was well tolerated in phase I and II trials, with the most common side effect being gastrointestinal symptoms. At the time of publication, phase II trials for fostamatinib were ongoing in patients with RA, ITP and B-cell lymphomas. The Syk inhibitor appears to be a promising therapeutic for immunological diseases, but further data are required to establish the efficacy and long-term safety of the drug in humans.
SOLUTION: Which enzyme is inhibited by a drug fostamatinib?
PROBLEM: The IUCN, however, ranks the Canada warbler as a species of least concern.
SOLUTION:
|
What is the status of Canada warbler?
| 8
|
NIv2
|
task470_mrqa_question_generation
|
fs_opt
|
Given a context passage, generate a question from the passage such that its answer is shortest continous span from the passage.
Q: Throughout 1476, supporters of Joanna from the nobility continued to submit to Isabella and Ferdinand, particularly those from the Pacheco-Giron lineage: Juan Tellez-Giron and his brother Rodrigo; Luis de Portocarrero; and, in September, the Marquis of Villena. In November 1476, Isabella's troops captured the castle of Toro. In the following months, they took control of the last bordering localities controlled by the Portuguese and dealt with their adversaries in Extremadura. In July 1477, Isabella arrived in Seville, the most populous city of Castile, with the objective of asserting her power over the nobility of Andalusia. In April 1476, Isabella and Ferdinand gave their first exculpation to the Marquis of Cadiz. He had been regaining power while his rival, the Duke of Medina Sidonia, initially the main Isabella supporter in Andalusia, had been falling into dishonour. Through skilful negotiations, the Queen managed to take control of the main strongholds of Seville occupied by the Marquis and the Duke and, instead of returning them to their legitimate owners, named others as their heads. She prohibited both nobles from entering the city of Seville, under the pretext that their simultaneous presence there would risk violent conflicts. In this way the Duke's political dominance over Seville disappeared, and the city passed into the control of the Crown. One of the few nobles that refused to submit to the monarchs was Marshall Fernan Arias de Saavedra. Isabella's troops laid siege to his fortress at Utrera, and conquered it by assault in March 1478. The defeated suffered harsh repression. The first son of the monarchs, John of Aragon and Castile, was born in Seville on June 30, 1478, which opened new possibilities for dynastic stability of the Isabellian side.
A: What event happened first, Isabella arriving in Seville or Isabella and Ferdinand giving their first exculpation to the Marquis of Cadiz?
****
Q: An 11-day embryonic Swiss Webster/NIH mouse cDNA library was screened with a partial murine selenoprotein P cDNA probe and a murine selenoprotein-P-type cDNA clone of 2075 bp length was obtained. The clone contained a 5'-leader sequence of 132 bp length, the selenoprotein P coding frame, and 803 base pairs in the 3' untranslated region. Alignment and RNA folding studies revealed the presence of two well conserved selenocysteine inserting motifs in the 3' flanking region. The deduced polypeptide sequence comprises 380 residues including ten selenocysteines. Identical amino acid residues in homologous positions are 86%, 71%, and 64% when compared to the previously reported selenoprotein P sequences of rat, man, and cattle, respectively. The comparatively low similarity between the selenoprotein P sequences reported so far leaves open the question whether they belong to the same molecular clade.
A: Which is the human selenoprotein that contains several Se-Cys residues?
****
Q: Interleukin-1 (IL-1) is a key orchestrator in inflammatory and several immune responses. IL-1 exerts its effects through interleukin-1 receptor type I (IL-1RI) and interleukin-1 receptor accessory protein (IL-1RAcP), which together form a heterotrimeric signaling-competent complex. Canakinumab and gevokizumab are highly specific IL-1 monoclonal antibodies. Canakinumab is known to neutralize IL-1 by competing for binding to IL-1R and therefore blocking signaling by the antigen:antibody complex. Gevokizumab is claimed to be a regulatory therapeutic antibody that modulates IL-1 bioactivity by reducing the affinity for its IL-1RI:IL-1RAcP signaling complex. How IL-1 signaling is affected by both canakinumab and gevokizumab was not yet experimentally determined. We have analyzed the crystal structures of canakinumab and gevokizumab antibody binding fragment (Fab) as well as of their binary complexes with IL-1. Furthermore, we characterized the epitopes on IL-1 employed by the antibodies by NMR epitope mapping studies. The direct comparison of NMR and X-ray data shows that the epitope defined by the crystal structure encompasses predominantly those residues whose NMR resonances are severely perturbed upon complex formation. The antigen:Fab co-structures confirm the previously identified key contact residues on IL-1 and provide insight into the mechanisms leading to their distinct modulation of IL-1 signaling. A significant steric overlap of the binding interfaces of IL-1R and canakinumab on IL-1 causes competitive inhibition of the association of IL-1 and its receptor. In contrast, gevokizumab occupies an allosteric site on IL-1 and complex formation results in a minor reduction of binding affinity to IL-1RI. This suggests two different mechanisms of IL-1 pathway attenuation.
A:
|
Which molecule is targeted by the drug Gevokizumab?
****
| 4
|
NIv2
|
task470_mrqa_question_generation
|
fs_opt
|
Given the task definition, example input & output, solve the new input case.
Given a context passage, generate a question from the passage such that its answer is shortest continous span from the passage.
Example: In 1582 the united provinces invited francis, duke of anjou to lead them; but after a failed attempt to take antwerp in 1583, the duke left the netherlands again. after the assassination of william of orange (10 july 1584), both henry iii of france and elizabeth i of england declined the offer of sovereignty. however, the latter agreed to turn the united provinces into a protectorate of england (treaty of nonsuch, 1585), and sent the earl of leicester as governor-general. this was unsuccessful and in 1588 the provinces became a confederacy. the union of utrecht is regarded as the foundation of the republic of the seven united provinces, which was not recognized by the spanish empire until the peace of westphalia in 1648.
Output: In what year did francis, duke of anjou leave the netherlands?
The generated question is perfect. Because the question is based on second sentence of the input passage and its answer is 1583.
New input case for you: RNA editing by deamination of specific adenosine bases to inosines during pre-mRNA processing generates edited isoforms of proteins. Recoding RNA editing is more widespread in Drosophila than in vertebrates. Editing levels rise strongly at metamorphosis, and Adar(5G1) null mutant flies lack editing events in hundreds of CNS transcripts; mutant flies have reduced viability, severely defective locomotion and age-dependent neurodegeneration. On the other hand, overexpressing an adult dADAR isoform with high enzymatic activity ubiquitously during larval and pupal stages is lethal. Advantage was taken of this to screen for genetic modifiers; Adar overexpression lethality is rescued by reduced dosage of the Rdl (Resistant to dieldrin), gene encoding a subunit of inhibitory GABA receptors. Reduced dosage of the Gad1 gene encoding the GABA synthetase also rescues Adar overexpression lethality. Drosophila Adar(5G1) mutant phenotypes are ameliorated by feeding GABA modulators. We demonstrate that neuronal excitability is linked to dADAR expression levels in individual neurons; Adar-overexpressing larval motor neurons show reduced excitability whereas Adar(5G1) null mutant or targeted Adar knockdown motor neurons exhibit increased excitability. GABA inhibitory signalling is impaired in human epileptic and autistic conditions, and vertebrate ADARs may have a relevant evolutionarily conserved control over neuronal excitability.
Output:
|
Which is the major RNA editing enzyme in Drosophila melanogaster?
| 1
|
NIv2
|
task470_mrqa_question_generation
|
fs_opt
|
Given a context passage, generate a question from the passage such that its answer is shortest continous span from the passage.
One example: In 1582 the united provinces invited francis, duke of anjou to lead them; but after a failed attempt to take antwerp in 1583, the duke left the netherlands again. after the assassination of william of orange (10 july 1584), both henry iii of france and elizabeth i of england declined the offer of sovereignty. however, the latter agreed to turn the united provinces into a protectorate of england (treaty of nonsuch, 1585), and sent the earl of leicester as governor-general. this was unsuccessful and in 1588 the provinces became a confederacy. the union of utrecht is regarded as the foundation of the republic of the seven united provinces, which was not recognized by the spanish empire until the peace of westphalia in 1648.
Solution is here: In what year did francis, duke of anjou leave the netherlands?
Explanation: The generated question is perfect. Because the question is based on second sentence of the input passage and its answer is 1583.
Now, solve this: Turner's syndrome is defined as a congenital disease determining by quantitative and/or structural aberrations of one from two X chromosomes with frequent presence of mosaicism. Clinically it is characterized by growth and body proportion abnormalities, gonadal dysgenesis resulting in sexual infantilism, primary amenorrhoea, infertility, characteristic stigmata, anomalies of heart, renal and bones and the presence of some diseases like Hashimoto thyroiditis with hypothyroidism, diabetes mellitus type 2, osteoporosis, hypertension. Turner's syndrome occurs in 1:2000 to 1:2500 female livebirth. The most frequent X chromosome aberrations in patients with phenotype of Turner syndrome are as follows: X monosomy - 45,X; mosaicism (50-75%), including 45,X/46,XX (10-15%), 45,X/46,XY (2-6%), 45,X/46,X,i(Xq), 45,X/46,X,del(Xp), 45,X/46,XX/47,XXX; aberration of X structure: total or partial deletion of short arm of X chromosome (46,X,del(Xp)) isochromosom of long arm of X chromosome (46,X,(i(Xq)), ring chromosome (46, X,r(X)), marker chromosome (46,X+m). Searching of X chromosome and mapping and sequencing of genes located at this chromosome (such as SHOX, ODG2, VSPA, SOX 3) have made possible to look for linkage between phenotypes and adequate genes or regions of X chromosome. In this paper current data concerning correlation between phenotype and karyotype in patients with TS have been presented.
Solution:
|
What chromosome is affected in Turner's syndrome?
| 6
|
NIv2
|
task470_mrqa_question_generation
|
fs_opt
|
You will be given a definition of a task first, then an example. Follow the example to solve a new instance of the task.
Given a context passage, generate a question from the passage such that its answer is shortest continous span from the passage.
In 1582 the united provinces invited francis, duke of anjou to lead them; but after a failed attempt to take antwerp in 1583, the duke left the netherlands again. after the assassination of william of orange (10 july 1584), both henry iii of france and elizabeth i of england declined the offer of sovereignty. however, the latter agreed to turn the united provinces into a protectorate of england (treaty of nonsuch, 1585), and sent the earl of leicester as governor-general. this was unsuccessful and in 1588 the provinces became a confederacy. the union of utrecht is regarded as the foundation of the republic of the seven united provinces, which was not recognized by the spanish empire until the peace of westphalia in 1648.
Solution: In what year did francis, duke of anjou leave the netherlands?
Why? The generated question is perfect. Because the question is based on second sentence of the input passage and its answer is 1583.
New input: Selenocysteine (Sec), the 21st amino acid in protein, is encoded by UGA. The Sec insertion sequence (SECIS) element, which is the stem-loop structure present in 3' untranslated regions (UTRs) of eukaryotic selenoprotein-encoding genes, is essential for recognition of UGA as a codon for Sec rather than as a stop signal. We now report the identification of a new eukaryotic selenoprotein, designated selenoprotein M (SelM). The 3-kb human SelM-encoding gene has five exons and is located on chromosome 22 but has not been correctly identified by either Celera or the public Human Genome Project. We characterized human and mouse SelM cDNA sequences and expressed the selenoprotein in various mammalian cell lines. The 3" UTR of the human, mouse, and rat SelM-encoding genes lacks a canonical SECIS element. Instead, Sec is incorporated in response to a conserved mRNA structure, in which cytidines are present in place of the adenosines previously considered invariant. Substitution of adenosines for cytidines did not alter Sec incorporation; however, other mutant structures did not support selenoprotein synthesis, demonstrating that this new form of SECIS element is functional. SelM is expressed in a variety of tissues, with increased levels in the brain. It is localized to the perinuclear structures, and its N-terminal signal peptide is necessary for protein translocation.
Solution:
|
What is the name of the stem loop present in the 3' end of genes encoding for selenoproteins?
| 0
|
NIv2
|
task470_mrqa_question_generation
|
fs_opt
|
Given a context passage, generate a question from the passage such that its answer is shortest continous span from the passage.
Example input: In 1582 the united provinces invited francis, duke of anjou to lead them; but after a failed attempt to take antwerp in 1583, the duke left the netherlands again. after the assassination of william of orange (10 july 1584), both henry iii of france and elizabeth i of england declined the offer of sovereignty. however, the latter agreed to turn the united provinces into a protectorate of england (treaty of nonsuch, 1585), and sent the earl of leicester as governor-general. this was unsuccessful and in 1588 the provinces became a confederacy. the union of utrecht is regarded as the foundation of the republic of the seven united provinces, which was not recognized by the spanish empire until the peace of westphalia in 1648.
Example output: In what year did francis, duke of anjou leave the netherlands?
Example explanation: The generated question is perfect. Because the question is based on second sentence of the input passage and its answer is 1583.
Q: Maria is a free-spirited young Austrian woman studying to become a nun at Nonnberg Abbey in Salzburg in 1938. Her love of music and the mountains, her youthful enthusiasm and imagination, and her lack of discipline cause some concern among the nuns. The Mother Abbess, believing Maria would be happier outside the abbey, sends her to the villa of retired naval officer Captain Georg von Trapp to be governess to his seven childrenLiesl, Friedrich, Louisa, Kurt, Brigitta, Marta, and Gretl. The Captain has been raising his children alone using strict military discipline following the death of his first wife. Although the children misbehave at first, Maria responds with kindness and patience, and soon the children come to trust and respect her. While the Captain is away in Vienna, Maria makes play clothes for the children and takes them around Salzburg and the surrounding mountains, and she teaches them how to sing. When the Captain returns to the villa with Baroness Elsa Schraeder, a wealthy socialite, and their mutual friend, Max Detweiler, they are greeted by Maria and the children returning from a boat ride on the lake that concludes when their boat overturns. Displeased by his children's clothes and activities, and Maria's impassioned appeal that he get closer to his children, the Captain orders her to return to the abbey. Just then he hears singing coming from inside the house and is astonished to see his children singing for the Baroness. Filled with emotion, the Captain joins his children, singing for the first time in years. Afterwards, he apologizes to Maria and asks her to stay. Impressed by the children's singing, Max proposes he enter them in the upcoming Salzburg Festival but the suggestion is immediately rejected by the Captain who will not allow his children to sing in public. He does agree, however, to organize a grand party at the villa. The night of the party, while guests in formal attire waltz in the ballroom, Maria and the children look on from the garden terrace. When the Captain notices Maria teaching Kurt the traditional Landler folk dance, he cuts in and partners with Maria in a graceful performance, culminating in a close embrace. Confused about her feelings, Maria blushes and breaks away. Later, the Baroness, who noticed the Captain's attraction to Maria, hides her jealousy while convincing Maria that she must return to the abbey. Back at the abbey, when Mother Abbess learns that Maria has stayed in seclusion to avoid her feelings for the Captain, she encourages her to return to the villa to look for her life. After Maria returns to the villa, she learns about the Captain's engagement to the Baroness and agrees to stay until they find a replacement governess. The Captain's feelings for Maria, however, have not changed, and after breaking off his engagement the Captain and Maria are married. While they are on their honeymoon, Max enters the children in the Salzburg Festival against their father's wishes. When they learn that Austria has been annexed into the Third Reich in the Anschluss, the couple return to their home, where a telegram awaits informing the Captain that he must report to the German Naval Headquarters in Bremerhaven to accept a commission in the German Navy. Strongly opposed to the Nazis and the Anschluss, the Captain tells his family they must leave Austria immediately. That night, as the von Trapp family attempt to leave, they are stopped by German soldiers waiting outside the villa. When questioned by Gauleiter Hans Zeller, the Captain maintains they are headed to the Salzburg Festival to perform. Zeller insists on escorting them to the festival, after which his men will accompany the Captain to Bremerhaven. Later that night at the festival, during their final number, the von Trapp family slip away and seek shelter at the nearby abbey, where Mother Abbess hides them in the cemetery crypt. Nazi soldiers soon arrive and search the abbey, but the family is able to escape using the caretaker's car. When the soldiers attempt to pursue, they discover their cars will not start as two nuns have removed parts of their engines. The next morning, after driving to the border, the von Trapp family make their
A:
|
Who does Maria marry?
| 3
|
NIv2
|
task470_mrqa_question_generation
|
fs_opt
|
Given a context passage, generate a question from the passage such that its answer is shortest continous span from the passage.
Input: Consider Input: The Linth (pronounced (lnt) ''lint'') is a Swiss river that rises near the village of Linthal in the mountains of the canton of Glarus, and eventually flows into the Obersee section of Lake Zurich.
Output: What river does Linth turn into?
Input: Consider Input: Harvey Shine (Dustin Hoffman) works as a jingle writer for television commercials in Manhattan, a job not in keeping with his one-time aspiration to be a jazz composer and pianist. We see him at work and he is very good at what he does. However, his boss does not seem impressed with his latest output. As Harvey departs for London to attend his daughter Susan's wedding, his boss actually suggests that he spend more time there than he had originally planned. Harvey declines, making the point that he needs to be back for an upcoming pitch to an old client. His boss insists that it is being done by other musicians, and that Harvey's latest work was his last chance to keep his job.On the plane, Harvey tries to chat up a fellow passenger, but she is having none of it. He is left sitting there with egg on his face and we come to regard him as even more of a loser.Meanwhile, we witness the mildly strained relationship between Kate Walker (Emma Thompson), a single Londoner, and her mother, whose husband left years earlier. Kate tries to reassure her mother that despite being single, she may yet find a man. Further, Kate tells her mom to quit worrying about the new Polish neighbor who has moved in next door and seems to be stacking a lot of firewood.Upon arrival at Heathrow Airport in London, Harvey encounters Kate at her job collecting statistics from passengers as they pass through the terminals. She attempts to question him about his reasons for visiting the UK. Tired and anxious to get to his hotel, Harvey brusquely dismisses her when she approaches him to ask questions.Harvey heads for the hotel to check in and discovers that he is the first one to arrive. Upon calling his daughter to double check where everyone else is when they were all supposed to be staying together, he learns that his ex-wife Jean actually rented a house to accommodate family and friends from the States and he is the only one at the hotel.After a brief nap, he showers and hurriedly dresses. On the way to the rehearsal dinner in the taxi cab, he realizes the anti-shoplifting device is still attached to the sleeve of his jacket. And to make matter worse, he has worn a white suit (thinking this was requested) while all the other men wore black. During the meal, it becomes increasingly clear Harvey is considered a mere guest and the role of father of the bride has been delegated to Jean's husband Brian. To add insult to injury, Brian stands to give the toast, and recollects the vacation they all spent in Rome, and his stepson-in-law-to-be embraces him and calls him Dad. Just before leaving back to his hotel, when Harvey tells Susan (with whom he has shared a strained relationship since his divorce) that he will be attending the ceremony but not the subsequent reception because he needs to return to the States for an important meeting, she informs him she has asked Brian to give her away.Meanwhile, Kate is set up on a blind date by a well meaning co-worker that does not go well. When she returns to the table after taking yet another call from her mother, she discovers her younger date has invited some of his younger friends to join them. Feeling unwanted and excluded from the conversation, she eventually excuses herself and goes home. As it turns out, Kate's increasingly neurotic mother seems convinced that her Polish neighbor is some kind of murderer because she sees him toting strange looking, lumpy packages into a shed in the back yard.The following morning Harvey attends Susan's wedding, but heavy traffic delays his arrival back to Heathrow, and he misses his plane. When he calls his boss Marvin in NYC to inform him he will be returning a day later than planned and that he will try to get there as soon as possible, he is told that he is fired.In his glum mood, Harvey makes his way to the airport bar and starts slugging down scotch, determined to drown his sorrows. Kate is sitting in the lounge reading
Output: Who has Harvey had a strained relationship with since the divorce?
Input: Consider Input: Selenocysteine (Sec), the 21st amino acid in protein, is encoded by UGA. The Sec insertion sequence (SECIS) element, which is the stem-loop structure present in 3' untranslated regions (UTRs) of eukaryotic selenoprotein-encoding genes, is essential for recognition of UGA as a codon for Sec rather than as a stop signal. We now report the identification of a new eukaryotic selenoprotein, designated selenoprotein M (SelM). The 3-kb human SelM-encoding gene has five exons and is located on chromosome 22 but has not been correctly identified by either Celera or the public Human Genome Project. We characterized human and mouse SelM cDNA sequences and expressed the selenoprotein in various mammalian cell lines. The 3" UTR of the human, mouse, and rat SelM-encoding genes lacks a canonical SECIS element. Instead, Sec is incorporated in response to a conserved mRNA structure, in which cytidines are present in place of the adenosines previously considered invariant. Substitution of adenosines for cytidines did not alter Sec incorporation; however, other mutant structures did not support selenoprotein synthesis, demonstrating that this new form of SECIS element is functional. SelM is expressed in a variety of tissues, with increased levels in the brain. It is localized to the perinuclear structures, and its N-terminal signal peptide is necessary for protein translocation.
|
Output: What is the name of the stem loop present in the 3' end of genes encoding for selenoproteins?
| 2
|
NIv2
|
task470_mrqa_question_generation
|
fs_opt
|
Given a context passage, generate a question from the passage such that its answer is shortest continous span from the passage.
[Q]: This March is a busy month in Shanghai.There's a lot to do.Here are the highlights. Live Music - Late Night Jazz Enjoy real American jazz from Herbie Davis, the famous trumpet player.He's coming with his new 7-piece band, Herbie's Heroes.Herbie is known to play well into the early hours, so don't expect to get much sleep.This is Herbie's third visit to Shanghai.The first two were sold out, so get your tickets quickly. PLACE: The Jazz Club DATES: 15---23 March PRICE: Y=80,120 TIME: 10:00p.m.till late! TEL: 6466--8736 Scottish dancing Take your partners and get ready to dance till you drop.Scottish dancing is fun and easy to learn.Instructors will demonstrate the dances.The live band, Gordon Stroppie and the Weefrees, are also excellent. PLACE: Jack Stein's DATES: every Monday PRICE: Y60 including one drink TIME: 7:00 ---0:00 p.m. TEL: 6402-1877 Exhibitions - Shanghai Museum There are 120,000 pieces on show here.You can see the whole of Chinese history under one roof.It's always interesting to visit, but doubly so at the moment with the Egyptian Tombs exhibition.There are lots of mummies and more gold than you've ever seen before.Let us know if you see a mummy move! PLACE: Shanghai Museum PRICE: Y=30 (Y= 15 for students) TEL: 6888-6888 DATES: daily TIME: Monday - Friday 9:00a.m.- 5:00p.m., Weekends 9:00a.m.--- 9:00p.m. Dining - Sushi chef in town Sushi is getting really big in Shanghai.In Japan, it's become an art form.The most famous Sushi 'artist' is Yuki Kamura.She's also one of the few female chefs in Japan.She'll be at Sushi Scene all of this month. PLACE: Sushi Scene in the Shanghai Hotel DATES: all month PRICE: Y=200 TIME: lunchtime TEL: 6690-3211 For a full listing of events, see our website.
[A]: Suppose you are going to attend an activity at 8: 00p.m.on Saturday, which one can you choose?
[Q]: MicroRNAs (miRNAs) constitute a large family of noncoding RNAs that function as guide molecules in diverse gene silencing pathways. Current efforts are focused on the regulatory function of miRNAs, while little is known about how these unusual genes themselves are regulated. Here we present the first direct evidence that miRNA genes are transcribed by RNA polymerase II (pol II). The primary miRNA transcripts (pri-miRNAs) contain cap structures as well as poly(A) tails, which are the unique properties of class II gene transcripts. The treatment of human cells with alpha-amanitin decreased the level of pri-miRNAs at a concentration that selectively inhibits pol II activity. Furthermore, chromatin immunoprecipitation analyses show that pol II is physically associated with a miRNA promoter. We also describe, for the first time, the detailed structure of a miRNA gene by determining the promoter and the terminator of mir-23a approximately 27a approximately 24-2. These data indicate that pol II is the main, if not the only, RNA polymerase for miRNA gene transcription. Our study offers a basis for understanding the structure and regulation of miRNA genes.
[A]: Which polymerase transcribes pri-miRNAs?
[Q]: Facioscapulohumeral dystrophy (FSHD) is characterized by chromatin relaxation of the D4Z4 macrosatellite array on chromosome 4 and expression of the D4Z4-encoded DUX4 gene in skeletal muscle. The more common form, autosomal dominant FSHD1, is caused by contraction of the D4Z4 array, whereas the genetic determinants and inheritance of D4Z4 array contraction-independent FSHD2 are unclear. Here, we show that mutations in SMCHD1 (encoding structural maintenance of chromosomes flexible hinge domain containing 1) on chromosome 18 reduce SMCHD1 protein levels and segregate with genome-wide D4Z4 CpG hypomethylation in human kindreds. FSHD2 occurs in individuals who inherited both the SMCHD1 mutation and a normal-sized D4Z4 array on a chromosome 4 haplotype permissive for DUX4 expression. Reducing SMCHD1 levels in skeletal muscle results in D4Z4 contraction-independent DUX4 expression. Our study identifies SMCHD1 as an epigenetic modifier of the D4Z4 metastable epiallele and as a causal genetic determinant of FSHD2 and possibly other human diseases subject to epigenetic regulation.
[A]:
|
What is the mode of inheritance of Facioscapulohumeral muscular dystrophy (FSHD)?
| 5
|
NIv2
|
task470_mrqa_question_generation
|
fs_opt
|
Given a context passage, generate a question from the passage such that its answer is shortest continous span from the passage.
One example: In 1582 the united provinces invited francis, duke of anjou to lead them; but after a failed attempt to take antwerp in 1583, the duke left the netherlands again. after the assassination of william of orange (10 july 1584), both henry iii of france and elizabeth i of england declined the offer of sovereignty. however, the latter agreed to turn the united provinces into a protectorate of england (treaty of nonsuch, 1585), and sent the earl of leicester as governor-general. this was unsuccessful and in 1588 the provinces became a confederacy. the union of utrecht is regarded as the foundation of the republic of the seven united provinces, which was not recognized by the spanish empire until the peace of westphalia in 1648.
Solution is here: In what year did francis, duke of anjou leave the netherlands?
Explanation: The generated question is perfect. Because the question is based on second sentence of the input passage and its answer is 1583.
Now, solve this: The origin of brain tumors has attracted much controversy. Recent advances in neural stem cell biology coupled with the new concepts of central nervous system development have raised interesting possibilities regarding the oncogenic properties of neural stem/progenitor cells. To elucidate these putative properties further, the clinical materials from an infant brain tumor were analyzed, focusing on the relation with the neural stem/progenitor cells. The expression of neural stem/progenitor cell markers in the tumor cells and the cellular components of the infant brain tumor were examined using immunohistochemistry. The tumor cell biology was analyzed both in culture and in the grafted brain environment. Three main bodies of evidence were demonstrated indicating that the tumor was of possible subventricular zone postnatal or adult normal neural stem cell origin. First, in the tumor specimen we demonstrated the strong positive expression of the neural stem/progenitor cell markers, nestin and Musashi-1. Second, immunohistochemistry revealed the presence of neuronal, astrocytic, and immature precursor cells in the tumor tissue, similar to the cellular components of the subventricular zone, thereby pointing to the subventricular zone as the possible origin of the tumor. The subventricular zone also is one of the strong candidates for the location of postnatal/adult neural stem cells. This cellular evidence was strengthened further by the clinicoradiological findings that demonstrated the involvement of the subventricular zone of the lateral ventricle by the tumor. Third, in the in vitro and in vivo experiments, a dynamic shift in expression patterns between neural stem cells (nestin, Musashi-1) and differentiated cells (glial fibrillary acidic protein, neuron-specific Class III beta-tubulin) markers was seen, similar to the proposed behavior of postnatal/adult neural stem cells in situ. These findings suggest that this brain tumor originated from neural stem cells located in the subventricular zone, and the further possibility of the general oncogenic potential of neural stem cells.
Solution:
|
Which intermediate filament (IF) protein can be used as a non-specific marker of the neuronal precursor cells of the subventricular zone?
| 6
|
NIv2
|
task470_mrqa_question_generation
|
fs_opt
|
Given a context passage, generate a question from the passage such that its answer is shortest continous span from the passage.
Example: In 1582 the united provinces invited francis, duke of anjou to lead them; but after a failed attempt to take antwerp in 1583, the duke left the netherlands again. after the assassination of william of orange (10 july 1584), both henry iii of france and elizabeth i of england declined the offer of sovereignty. however, the latter agreed to turn the united provinces into a protectorate of england (treaty of nonsuch, 1585), and sent the earl of leicester as governor-general. this was unsuccessful and in 1588 the provinces became a confederacy. the union of utrecht is regarded as the foundation of the republic of the seven united provinces, which was not recognized by the spanish empire until the peace of westphalia in 1648.
Example solution: In what year did francis, duke of anjou leave the netherlands?
Example explanation: The generated question is perfect. Because the question is based on second sentence of the input passage and its answer is 1583.
Problem: Although peak finding in next-generation sequencing (NGS) datasets has been addressed extensively, there is no consensus on how to analyze and process biological replicates. Furthermore, most peak finders do not focus on accurate determination of enrichment site widths and are not widely applicable to different types of datasets. We developed JAMM (Joint Analysis of NGS replicates via Mixture Model clustering): a peak finder that can integrate information from biological replicates, determine enrichment site widths accurately and resolve neighboring narrow peaks. JAMM is a universal peak finder that is applicable to different types of datasets. We show that JAMM is among the best performing peak finders in terms of site detection accuracy and in terms of accurate determination of enrichment sites widths. In addition, JAMM's replicate integration improves peak spatial resolution, sorting and peak finding accuracy. JAMM is available for free and can run on Linux machines through the command line: [Link]
|
Solution: Which peak calling algorithm employs mixture model clustering under the hood?
| 5
|
NIv2
|
task470_mrqa_question_generation
|
fs_opt
|
TASK DEFINITION: Given a context passage, generate a question from the passage such that its answer is shortest continous span from the passage.
PROBLEM: NASCAR Thunder 2002 is a racing simulator video game developed by EA Tiburon and published by EA Sports that came out for the Sony PlayStation, Sony PlayStation 2, and Xbox.
SOLUTION: Who worked on NASCAR Thunder 2002?
PROBLEM: The Battle of Adwa (also known as Adowa, or sometimes by the Italian name Adua) was fought on 1 March 1896 between the Ethiopian Empire and the Kingdom of Italy near the town of Adwa, Ethiopia, in Tigray.
SOLUTION: The point in time of Battle of Adwa was when?
PROBLEM: Phoebe Campbell (c. 1847 -- 20 June 1872) was a Canadian woman who was hanged for the murder of her husband.
SOLUTION:
|
Which crime Phoebe Campbell is considered to have commited?
| 8
|
NIv2
|
task470_mrqa_question_generation
|
fs_opt
|
instruction:
Given a context passage, generate a question from the passage such that its answer is shortest continous span from the passage.
question:
Yana De Leeuw (born 6 September 1990) is a Belgian female former volleyball player, playing as a setter.
answer:
Which sex or gender can Yana De Leeuw be described as?
question:
People have been using sound to make music for thousands of years. They have invented many different kinds of musical instruments for this purpose. Despite their diversity, however, musical instruments share certain similarities. All musical instruments create sound by causing matter to vibrate. The vibrations start sound waves moving through the air. Most musical instruments use resonance to amplify the sound waves and make the sounds louder. Resonance occurs when an object vibrates in response to sound waves of a certain frequency. In a musical instrument such as a guitar, the whole instrument and the air inside it may vibrate when a single string is plucked. This causes constructive interference with the sound waves, which increases their amplitude. Most musical instruments have a way of changing the frequency of the sound waves they produce. This changes the pitch of the sounds. There are three basic categories of musical instruments: percussion, wind, and stringed instruments. In Figure Researchers at Lawrence Berkeley National Laboratory are pioneering a new way to recover 100-year-old record- ings. Found on fragile wax cylinders and early lacquer records, the sounds reveal a rich acoustic heritage, including languages long lost. For more information on how to recover recordings, see [Link] MEDIA Click image to the left or use the URL below. URL: Ultrasound has frequencies higher than the human ear can detect (higher than 20,000 hertz). Although we cant hear ultrasound, it is very useful. Uses include echolocation, sonar, and ultrasonography. Animals such as bats, whales, and dolphins send out ultrasound waves and use their echoes, or reflected waves, to identify the locations of objects they cannot see. This is called echolocation. Animals use echolocation to find prey and avoid running into objects in the dark. Figure 20.13 and the animation at the URL below show how a bat uses echolocation to locate insect prey. Sonar uses ultrasound in a way that is similar to echolocation. Sonar stands for sound navigation and ranging. It is used to locate underwater objects such as sunken ships or to determine how deep the water is. A sonar device is usually located on a boat at the surface of the water. The device is both a sender and a receiver (see Figure 20.14). It sends out ultrasound waves and detects reflected waves that bounce off underwater objects or the bottom of the water. If you watch the video at the URL below, you can see how sonar is used on a submarine. The distance to underwater objects or the bottom of the water can be calculated from the known speed of sound in water and the time it takes for the waves to travel to the object. The equation for the calculation is: Distance = Speed Time Assume, for example, that a sonar device on a ship sends an ultrasound wave to the bottom of the ocean. The speed of the sound through ocean water is 1437 m/s, and the wave travels to the bottom and back in 2 seconds. What is the distance from the surface to the bottom of the water? The sound wave travels to the bottom and back in 2 seconds, so it travels from the surface to the bottom in 1 second. Therefore, the distance from the surface to the bottom is: Distance = 1437 m/s 1 s = 1437 m You Try It! Problem: The sonar device on a ship sends an ultrasound wave to the bottom of the water at speed of 1437 m/s. The wave is reflected back to the device in 4 seconds. How deep is the water? Ultrasound can be used to "see" inside the human body. This use of ultrasound is called ultrasonography. Harmless ultrasound waves are sent inside the body, and the reflected waves are used to create an image on a screen. This technology is used to examine internal organs and unborn babies without risk to the patient. You can see an ultrasound image in Figure 20.15. You can see an animation showing how ultrasonography works at this URL: In this QUEST web extra, Stanford University astrophysicist Todd Hoeksema explains how solar sound waves are a vital ingredient to the science of helioseismology, in which the interior properties of the sun
answer:
use of ultrasound to locate underwater objects
question:
Originating in Germany, the Danube flows southeast for 2,860 km (1,780 mi), passing through or touching the border of Austria, Slovakia, Hungary, Croatia, Serbia, Romania, Bulgaria, Moldova and Ukraine before emptying into the Black Sea.
answer:
|
What body of water does Danube join?
| 9
|
NIv2
|
task470_mrqa_question_generation
|
fs_opt
|
Given a context passage, generate a question from the passage such that its answer is shortest continous span from the passage.
Let me give you an example: In 1582 the united provinces invited francis, duke of anjou to lead them; but after a failed attempt to take antwerp in 1583, the duke left the netherlands again. after the assassination of william of orange (10 july 1584), both henry iii of france and elizabeth i of england declined the offer of sovereignty. however, the latter agreed to turn the united provinces into a protectorate of england (treaty of nonsuch, 1585), and sent the earl of leicester as governor-general. this was unsuccessful and in 1588 the provinces became a confederacy. the union of utrecht is regarded as the foundation of the republic of the seven united provinces, which was not recognized by the spanish empire until the peace of westphalia in 1648.
The answer to this example can be: In what year did francis, duke of anjou leave the netherlands?
Here is why: The generated question is perfect. Because the question is based on second sentence of the input passage and its answer is 1583.
OK. solve this:
A house of cards? Sounds unbelievable, doesn't it? Not if the architect is 31-year-old Bryan Berg. He's made a career out of building fantastic card houses, stadiums, capitols, castles -- and the world's tallest card tower. How does he do it? Bryan's structures are amazing because they are made entirely of perfectly balanced, freestanding playing cards. He never uses glue, tape, or anything else to hold the cards together. Nor does he fold the cards. He's discovered another way to make a strong house of cards, using a trick from nature. To make plants strong, nature builds them with cells that have tough walls. Rows and rows of these cells form a grid that helps leaves and stems keep their shape. Bees use the same kind of repeating pattern to create strong honeycombs, where they live and store honey. Bryan designs similar grids, using cards to create a repeating pattern of cells. He begins with a single cell made by balancing four cards against one another to form a box. Then he repeats the cell over and over, expanding outward to form the grid, which makes a good foundation for a strong card structure. The larger the grid, the more weight it can carry. Sometimes Bryan uses several cards, instead of just one, to construct the cell walls, making the grid even stronger. The trick, he tells kids when he speaks in classrooms, is to place your cards as tightly together as possible when laying out your grid, making sure the cards are not leaning at all. After building this solid base, Bryan lays cards across the top to make the floor for the next "story" of the building. He may add towers, columns, steeples, or domes. Using the principle of repeating cells, Bryan builds structures of amazing strength. In the Cards Not surprisingly, Bryan has always been interested in building things. Growing up on a "big, old farm" in rural Iowa, he had plenty of room to play. "We were in the middle of nowhere," Bryan remembers, "with lots of space to do whatever we wanted. I was always making something, using things like sticks or bales of hay." Bryan's grandfather taught him how to stack cards. Bryan's two interests -- building and card stacking -- soon combined. But stacking in his family's farmhouse was challenging. "Our old house had wood floors that weren't all level," he reports. "And they weren't very firm. When people walked around, it was like 'earthquake action.' It was a challenge to build something that wouldn't fall down immediately." Bryan constructed tower after tower; he went through a lot of trial and error before he built anything taller than himself. When he placed a few decks of cards on top of his grid, he discovered how strong it was. Bryan's towers began to grow taller. How Tall Is Too Tall? Bryan's first Guinness World Record for the world's tallest card tower came in the spring of 1992, when he was in high school. Learning that the world record was 12 feet 10 inches, Bryan built a slim tower that topped out at 14 feet 6 inches. Done as a project for his geometry class, it took him 40 hours and 208 decks of cards. Since then he's gone on to win world records for even taller buildings. His latest winner measured 25 feet 3.5 inches and used about 2,400 decks of cards. _ Why don't these towers fall down? The key is in a good solid base, a repeating pattern of stories, and a tapering top. Bryan likes to point out how card buildings resemble real ones. They are built cell by cell, story by story. The separate parts make one strong whole. The heavier the building, the stronger and more stable it is. But the weight can't all be at the top. After spending so much time building something so cool, Bryan admits it's sometimes painful to see his structures destroyed. But he compares his work to the building of a sandcastle or an ice sculpture.
Answer:
|
What was Bryan's first world record?
| 8
|
NIv2
|
task470_mrqa_question_generation
|
fs_opt
|
Teacher: Given a context passage, generate a question from the passage such that its answer is shortest continous span from the passage.
Teacher: Now, understand the problem? If you are still confused, see the following example:
In 1582 the united provinces invited francis, duke of anjou to lead them; but after a failed attempt to take antwerp in 1583, the duke left the netherlands again. after the assassination of william of orange (10 july 1584), both henry iii of france and elizabeth i of england declined the offer of sovereignty. however, the latter agreed to turn the united provinces into a protectorate of england (treaty of nonsuch, 1585), and sent the earl of leicester as governor-general. this was unsuccessful and in 1588 the provinces became a confederacy. the union of utrecht is regarded as the foundation of the republic of the seven united provinces, which was not recognized by the spanish empire until the peace of westphalia in 1648.
Solution: In what year did francis, duke of anjou leave the netherlands?
Reason: The generated question is perfect. Because the question is based on second sentence of the input passage and its answer is 1583.
Now, solve this instance: Live Music--Late Night Jazz Enjoy real American jazz from Herbie Davis, the famous trumpet player. Heis known to play well into the late hours, so don't expect to get much sleep. Place: The Jazz Club Dates : 10 - 25 July Price: $ 100 -- 150 Time: 10:30 p.m. till late Tel: 4668736 Scottish Dancing Scottish dancing is nice and easy to learn. The wonderful dance from Britain will beshown. Place: Jack Stein's Dates :12 -19 July Price: $150 Time: 7:00 p.m.-10:00 p.m. Tel: 4021877 Shows in Shanxi Museum There are 12,000 pieces on show here. You can see the whole Chinese history. Place: Shanxi Museum Dates: Jun 1 - Aug 15 Price: $ 60 ( $ 30 for students) Time: Monday - Friday 9:00 a.m. - 5:00 p.m. Tel : 4886888 Weekends: 9:00 a.m.-9:00 p.m.
Student:
|
Which number should you call if you like jazz music?
| 2
|
NIv2
|
task470_mrqa_question_generation
|
fs_opt
|
Detailed Instructions: Given a context passage, generate a question from the passage such that its answer is shortest continous span from the passage.
See one example below:
Problem: In 1582 the united provinces invited francis, duke of anjou to lead them; but after a failed attempt to take antwerp in 1583, the duke left the netherlands again. after the assassination of william of orange (10 july 1584), both henry iii of france and elizabeth i of england declined the offer of sovereignty. however, the latter agreed to turn the united provinces into a protectorate of england (treaty of nonsuch, 1585), and sent the earl of leicester as governor-general. this was unsuccessful and in 1588 the provinces became a confederacy. the union of utrecht is regarded as the foundation of the republic of the seven united provinces, which was not recognized by the spanish empire until the peace of westphalia in 1648.
Solution: In what year did francis, duke of anjou leave the netherlands?
Explanation: The generated question is perfect. Because the question is based on second sentence of the input passage and its answer is 1583.
Problem: JMule is an open source file sharing client written in Java for eDonkey2000 networks.
Solution:
|
What is the programming language for JMule?
| 4
|
NIv2
|
task470_mrqa_question_generation
|
fs_opt
|
Given a context passage, generate a question from the passage such that its answer is shortest continous span from the passage.
Ex Input:
The French Revolution broke out in 1789. At the time France was in a crisis. The government was badly run and people's lives were miserable. King Louis XIV tried to control the national parliament and raise more taxes. But his effort failed. He ordered his troops to Versailles. The people thought that Louis intended to put down the Revolution by force. On July 14, 1789, they stormed and took the Bastille, where political prisoners were kept. Ever since that day, July 14 has been the French National Day. Louis tried to flee the country in 1792, to get support from Austria and Prussia. However, he was caught and put in prison. In September 1792, the monarchy was abolished _ . In the same year, Louis was executed. A few months later his wife, Marie also had her head cut off. The Revolution of France had frightened the other kings of Europe. Armies from Austria and Prussia began to march against France. The French raised republican armies to defend the nation. The Revolution went through a period of terror. Thousands of people lost their lives. In the end, power passed to Napoleon Bonaparte.
Ex Output:
What's this passage about?
Ex Input:
Heavily in debt, Clinton lobbied the Duke of Newcastle for profitable employment as an American governor: he was appointed Governor of the Province of New York in July 1741 and arrived in New York in September 1743 to take up his position. Promoted to rear-admiral on 10 December 1743 and vice-admiral on 23 June 1744, he sought to protect New York's Northern border from attack by the French: however liberal members of the New York assembly resisted his proposals as they wanted to maintain trade links with the French and with the Native Americans who were under French influence. James De Lancey, who had initially been his main adviser, turned against him and sought to block the governor's salary. Clinton therefore invited Sir William Johnson to take over responsibility for Native American affairs in 1746 and appointed Cadwallader Colden to be his advisor. Clinton was promoted to full admiral on 15 July 1747. Working with the Mohawk chief Hendrick Theyanoguin, Johnson was able to recruit Mohawk warriors to fight on the side of the British in 1747 during King George's War. After continuing disputes with the assembly over military expenditure and payment of the governor's salary, Clinton resigned as governor in October 1753.
Ex Output:
What happened second: Clinton was appointed Governor or promoted to rear-admiral?
Ex Input:
Live Music--Late Night Jazz Enjoy real American jazz from Herbie Davis, the famous trumpet player. Heis known to play well into the late hours, so don't expect to get much sleep. Place: The Jazz Club Dates : 10 - 25 July Price: $ 100 -- 150 Time: 10:30 p.m. till late Tel: 4668736 Scottish Dancing Scottish dancing is nice and easy to learn. The wonderful dance from Britain will beshown. Place: Jack Stein's Dates :12 -19 July Price: $150 Time: 7:00 p.m.-10:00 p.m. Tel: 4021877 Shows in Shanxi Museum There are 12,000 pieces on show here. You can see the whole Chinese history. Place: Shanxi Museum Dates: Jun 1 - Aug 15 Price: $ 60 ( $ 30 for students) Time: Monday - Friday 9:00 a.m. - 5:00 p.m. Tel : 4886888 Weekends: 9:00 a.m.-9:00 p.m.
Ex Output:
|
Which number should you call if you like jazz music?
| 1
|
NIv2
|
task470_mrqa_question_generation
|
fs_opt
|
Given a context passage, generate a question from the passage such that its answer is shortest continous span from the passage.
Example input: In 1582 the united provinces invited francis, duke of anjou to lead them; but after a failed attempt to take antwerp in 1583, the duke left the netherlands again. after the assassination of william of orange (10 july 1584), both henry iii of france and elizabeth i of england declined the offer of sovereignty. however, the latter agreed to turn the united provinces into a protectorate of england (treaty of nonsuch, 1585), and sent the earl of leicester as governor-general. this was unsuccessful and in 1588 the provinces became a confederacy. the union of utrecht is regarded as the foundation of the republic of the seven united provinces, which was not recognized by the spanish empire until the peace of westphalia in 1648.
Example output: In what year did francis, duke of anjou leave the netherlands?
Example explanation: The generated question is perfect. Because the question is based on second sentence of the input passage and its answer is 1583.
Q: With Steigerwalds departure in 1999, Mike Lange shared the broadcast booth with former Penguins defenseman Peter Taglianetti. Taglianetti, a two-time Stanley Cup winner with the team in 1991 and 1992, remained in the position for one season before being replaced by Ed Olczyk. Lange and Olczyk were broadcast partners from 2000 until 2003, when Olczyk left the booth to become the 18th head coach in Penguins history that had become upon due to the firing of previous Head Coach Rick Kehoe after the 200203 season. With Olczyks vacancy, the Penguins hired Bob Errey as their new color commentator for the start of the 200304 season (a position that he continues to hold as of the start of the 201213 season. Lange and Errey remained in the booth until 200506. After 26 seasons in the television broadcast booth, Mike Lange was not retained by FSN Pittsburgh. Instead, he was replaced by former broadcast partner Paul Steigerwald, who remained the TV play-by-play broadcaster for the team until the 201617 season. Lange returned to the radio broadcast booth and currently holds the position of radio play-by-play announcer, the same position he had held with the team in the mid-1970s. Following the 201617 season, Steigerwald moved back to the Penguins front office and NHL Network (U.S. TV network) personality Steve Mears was hired as the new television play-by-play announcer starting with the 201718 season.
A:
|
Who was play-by-play announcer first, Mears or Lange?
| 3
|
NIv2
|
task470_mrqa_question_generation
|
fs_opt
|
You will be given a definition of a task first, then an example. Follow the example to solve a new instance of the task.
Given a context passage, generate a question from the passage such that its answer is shortest continous span from the passage.
In 1582 the united provinces invited francis, duke of anjou to lead them; but after a failed attempt to take antwerp in 1583, the duke left the netherlands again. after the assassination of william of orange (10 july 1584), both henry iii of france and elizabeth i of england declined the offer of sovereignty. however, the latter agreed to turn the united provinces into a protectorate of england (treaty of nonsuch, 1585), and sent the earl of leicester as governor-general. this was unsuccessful and in 1588 the provinces became a confederacy. the union of utrecht is regarded as the foundation of the republic of the seven united provinces, which was not recognized by the spanish empire until the peace of westphalia in 1648.
Solution: In what year did francis, duke of anjou leave the netherlands?
Why? The generated question is perfect. Because the question is based on second sentence of the input passage and its answer is 1583.
New input: Adidas Championship Football is a soccer video game developed by Ocean Software in 1990.
Solution:
|
Who is originally behind the development of Adidas Championship Football?
| 0
|
NIv2
|
task470_mrqa_question_generation
|
fs_opt
|
Given a context passage, generate a question from the passage such that its answer is shortest continous span from the passage.
One example is below.
Q: In 1582 the united provinces invited francis, duke of anjou to lead them; but after a failed attempt to take antwerp in 1583, the duke left the netherlands again. after the assassination of william of orange (10 july 1584), both henry iii of france and elizabeth i of england declined the offer of sovereignty. however, the latter agreed to turn the united provinces into a protectorate of england (treaty of nonsuch, 1585), and sent the earl of leicester as governor-general. this was unsuccessful and in 1588 the provinces became a confederacy. the union of utrecht is regarded as the foundation of the republic of the seven united provinces, which was not recognized by the spanish empire until the peace of westphalia in 1648.
A: In what year did francis, duke of anjou leave the netherlands?
Rationale: The generated question is perfect. Because the question is based on second sentence of the input passage and its answer is 1583.
Q: Chronic myeloid leukemia (CML) was the first human malignant disease to be linked to a single, acquired genetic abnormality. Identification of the Bcr-Abl kinase fusion protein and its pivotal role in the pathogenesis of CML provided new opportunities to develop molecular-targeted therapies. Imatinib mesylate (IM, Gleevec, Novartis Pharmaceuticals, Basel, Switzerland), which specifically inhibits the autophosphorylation of the Abl TK, has improved the treatment of CML. However, resistance is often reported in patients with advanced-stage disease. Several novel TK inhibitors have been developed that override IM resistance mechanisms caused by point mutations within the Abl kinase domain. Inhibitors of Abl TK are divided into two main groups, namely, ATP-competitive and ATP noncompetitive inhibitors. The ATP-competitive inhibitors fall into two subclasses, the Src/Abl inhibitors, and the 2-phenylaminopyrimidine-based compounds. Dasatinib (formerly BMS-354825), AP23464, SKI-606, and PD166326 are classified as Src/Abl inhibitors, while nilotinib (AMN107) and INNO-406 (NS-187) belong to the latter subclass of inhibitors. Of these agents, dasatinib and nilotinib underwent clinical trials earlier than the others and favorable results are now accumulating. Clinical studies of the other compounds, including SKI-606 and INNO-406, have been performed in rapid succession. Because of their strong affinities for the ATP-binding site compared to IM, most ATP-competitive inhibitors may be effective in IM-resistant patients. However, an ATP-competitive inhibitor that can inhibit the phosphorylation of T315I Bcr-Abl has not yet been developed. Instead, ATP noncompetitive inhibitors, such as ON012380, Aurora kinase inhibitor MK0457 (VX-680), and p38 MAP kinase inhibitor BIRB-796, have been developed to address this problem. This review provides an update on the underlying pathophysiologies of disease progression and IM resistance, and discusses the development of new targeted TK inhibitors for managing CML and the importance of future strategies targeting CML stem cells.
A:
|
What tyrosine kinase, involved in a Philadelphia- chromosome positive chronic myelogenous leukemia, is the target of Imatinib (Gleevec)?
| 9
|
NIv2
|
task470_mrqa_question_generation
|
fs_opt
|
Detailed Instructions: Given a context passage, generate a question from the passage such that its answer is shortest continous span from the passage.
See one example below:
Problem: In 1582 the united provinces invited francis, duke of anjou to lead them; but after a failed attempt to take antwerp in 1583, the duke left the netherlands again. after the assassination of william of orange (10 july 1584), both henry iii of france and elizabeth i of england declined the offer of sovereignty. however, the latter agreed to turn the united provinces into a protectorate of england (treaty of nonsuch, 1585), and sent the earl of leicester as governor-general. this was unsuccessful and in 1588 the provinces became a confederacy. the union of utrecht is regarded as the foundation of the republic of the seven united provinces, which was not recognized by the spanish empire until the peace of westphalia in 1648.
Solution: In what year did francis, duke of anjou leave the netherlands?
Explanation: The generated question is perfect. Because the question is based on second sentence of the input passage and its answer is 1583.
Problem: Team Services, LLC is a Rockville, Maryland-based sports marketing firm.
Solution:
|
What is the city where Team Services, LLC is from?
| 4
|
NIv2
|
task470_mrqa_question_generation
|
fs_opt
|
You will be given a definition of a task first, then an example. Follow the example to solve a new instance of the task.
Given a context passage, generate a question from the passage such that its answer is shortest continous span from the passage.
In 1582 the united provinces invited francis, duke of anjou to lead them; but after a failed attempt to take antwerp in 1583, the duke left the netherlands again. after the assassination of william of orange (10 july 1584), both henry iii of france and elizabeth i of england declined the offer of sovereignty. however, the latter agreed to turn the united provinces into a protectorate of england (treaty of nonsuch, 1585), and sent the earl of leicester as governor-general. this was unsuccessful and in 1588 the provinces became a confederacy. the union of utrecht is regarded as the foundation of the republic of the seven united provinces, which was not recognized by the spanish empire until the peace of westphalia in 1648.
Solution: In what year did francis, duke of anjou leave the netherlands?
Why? The generated question is perfect. Because the question is based on second sentence of the input passage and its answer is 1583.
New input: One of China's most popular folk arts is paper cutting . Archaeological finds trace the tradition back to the 6thcentury; it is supposed that the beginnings of paper cutting were even a few centuries earlier. Paper cuttings are used for religious purposes, for decoration and as patterns . Today, paper cuttings are mainly used as decoration. They _ walls, windows, doors, columns mirrors, lamps and lanterns in homes. They are also used for decoration on presents, and are given as presents themselves. They are of special importance at festivals. At the Spring Festival for example, entrances are decorated with paper cuttings which are supposed to bring good luck. Paper cuttings are not produced by machine, but by hand. There are two kinds of paper cuttings; scissor cuttings and knife cuttings. Scissor cuttings are fashioned with scissors. Several pieces of paper--- up to eight pieces---are fastened together. The motif is then cut with sharp, pointed scissors. Knife cuttings are fashioned by putting several layers of paper on a relatively soft foundation consisting of a mixture of tallow and ashes. Following a pattern, the artist cuts the motif into the paper with a sharp knife which he usually holds vertically . The advantage of knife cuttings is that considerably more paper cuttings can be made in one operation than scissor cuttings. In the countryside, paper cuttings are usually made only by women and girls. This used to be one of the skills that every girl was to master and that were often used to judge brides . Professional paper cutting artists are, on the other hand, almost always men who have guaranteed incomes and work together in workshops.
Solution:
|
Which is the best title of this passage?
| 0
|
NIv2
|
task470_mrqa_question_generation
|
fs_opt
|
Given a context passage, generate a question from the passage such that its answer is shortest continous span from the passage.
[EX Q]: Plunkett finished the game with 16 out of 25 pass completions for 172 yards and a touchdown. Theismann threw for more yards than Plunkett (243), but was just 16 out of 35 and was intercepted twice. He was also sacked six times. Branch was the top receiver of the game with six receptions for 94 yards and a touchdown. Guy punted seven times for 299 yards (42.7 average), with 244 net yards (34.8 average) and planted five of his seven punts inside the 20. Martin recorded a sack, a pass deflection, and a fumble recovery. Riggins, who had rushed for over 100 yards in his last six postseason games, was held to 64 yards and a touchdown on 26 carries, with his longest gain being just 8 yards. Brown was their top receiver with three receptions for 93 yards. Tight end Clint Didier caught five passes for 65 yards. Garrett recorded 100 yards on kickoff returns, and one reception for 17 yards. Part of both of Allens touchdown runs were cutbacks, which, according to New York Daily News writer Larry Fox, burned an overpursuing Redskins defense.
[EX A]: Which player achieved more receptions, Branch or Brown?
[EX Q]: Everywhere man is altering the balance of nature.He is facilitating the spread of plants and animals into new regions, sometimes deliberately, sometimes unconsciously.He is covering huge areas with new kinds of plants, or with houses, factories, slag-heaps and other products of his civilization.He exterminates some species on a large scale, but favours the multiplication of others.In brief, he has done more in five thousand years to alter the biological aspect of the planet than has nature in five million. Many of these changes which he has brought about have had unforeseen consequences.Who would have thought that the throwing away of a piece of Canadian waterweed would have caused half the waterways of Britain to be blocked for a decade, or that the provision of pot cacti for lonely settlers' wives would have led to Eastern Australian being overrun with forests of Prickly Pear? Who would have prophesied that the cutting down of forests on the Adriatic coasts, or in parts of Central Africa, could have reduced the land to a semidesert, with the very soil washed away from the bare rock? Who would have thought that improved communications would have changed history by the spreading of disease-sleeping sickness into East Africa, measles into Oceania, very possibly malaria into ancient Greece? These are spectacular examples; but examples on a smaller scale are everywhere to be found.We make a nature sanctuary for rare birds, prescribing absolute security for all species; and we may find that some common and hardy kind of bird multiplies beyond measure and ousts the rare kinds in which we were particularly interested.We see, owing to some little change brought about by civilization, the starling spread over the English country-side in hordes.We improve the yielding capacities of our cattle; and find that now they exhaust the pastures which sufficed for less exigent stock.
[EX A]: What have spread diseases?
[EX Q]: Do you prefer British English or American English? Here are opinions from our readers. Andy: Well, being in British for 3 years now from New Zealand I've come to realize that a lot of British people pronounce words how Americans do. But in saying that, I guess the more educated British people do not pronounce words the way some Americans do. So, I prefer Educated British English. Bill: Well, I am studying English and I think British sounds funny and I prefer Americans sounds. Although I can tell that everyone else in my class loves British pronunciation and thinks American English is less pretty or even ugly. I don't agree at all, though. Cindy: At first British English accent sounds better and wonderful but then it gets annoying, so I love American English. Dale: I prefer the British accent. It sounds like someone reading a poem. I just like the pronunciation of the British people, very clear and sounds like music! British accent is more musical. Edward: When I listen to the BBC announcers, I notice that they're exploding the letters out, not pronouncing them. And some British people from the North of England or Scotland speak with strange accents. I mean it is difficult to understand their English. Frank: As a matter of fact, English for International Communication is very much like American accent. I love the American accent.
[EX A]:
|
Which reader didn't state clearly which pronunciation he or she preferred?
| 6
|
NIv2
|
task470_mrqa_question_generation
|
fs_opt
|
instruction:
Given a context passage, generate a question from the passage such that its answer is shortest continous span from the passage.
question:
Almost all surfaces reflect some of the light that strikes them. The still water of the lake in Figure 22.9 reflects almost all of the light that strikes it. The reflected light forms an image of nearby objects. An image is a copy of an object that is formed by reflected or refracted light. If a surface is extremely smooth, like very still water, then an image formed by reflection is sharp and clear. This is called regular reflection. If the surface is even slightly rough, an image may not form, or if there is an image, it is blurry or fuzzy. This is called diffuse reflection. Both types of reflection are represented in Figure 22.10. You can also see animations of both types of reflection at this URL: [Link] In Figure 22.10, the waves of light are represented by arrows called rays. Rays that strike the surface are referred to as incident rays, and rays that reflect off the surface are known as reflected rays. In regular reflection, all the rays are reflected in the same direction. This explains why regular reflection forms a clear image. In diffuse reflection, in contrast, the rays are reflected in many different directions. This is why diffuse reflection forms, at best, a blurry image. One thing is true of both regular and diffuse reflection. The angle at which the reflected rays bounce off the surface is equal to the angle at which the incident rays strike the surface. This is the law of reflection, and it applies to the reflection of all light. The law is illustrated in Figure 22.11 and in the animation at this URL: Mirrors are usually made of glass with a shiny metal backing that reflects all the light that strikes it. Mirrors may have flat or curved surfaces. The shape of a mirrors surface determines the type of image the mirror forms. For example, the image may be real or virtual. A real image forms in front of a mirror where reflected light rays actually meet. It is a true image that could be projected on a screen. A virtual image appears to be on the other side of the mirror. Of course, reflected rays dont actually go behind a mirror, so a virtual image doesnt really exist. It just appears to exist to the human eye and brain. Most mirrors are plane mirrors. A plane mirror has a flat reflective surface and forms only virtual images. The image formed by a plane mirror is also life sized. But something is different about the image compared with the real object in front of the mirror. Left and right are reversed. Look at the man shaving in Figure 22.12. He is using his right hand to hold the razor, but his image appears to be holding the razor in the left hand. Almost all plane mirrors reverse left and right in this way. Some mirrors have a curved rather than flat surface. Curved mirrors can be concave or convex. A concave mirror is shaped like the inside of a bowl. This type of mirror forms either real or virtual images, depending on where the object is placed relative to the focal point. The focal point is the point in front of the mirror where the reflected rays intersect. You can see how concave mirrors form images in Figure 22.13 and in the interactive animation at the URL below. The animation allows you to move an object to see how its position affects the image. Concave mirrors are used behind car headlights. They focus the light and make it brighter. They are also used in some telescopes. The other type of curved mirror, a convex mirror, is shaped like the outside of a bowl. This type of mirror forms only virtual images. The image is always right-side up and smaller than the actual object, which makes the object appear farther away than it really is. You can see how a convex mirror forms an image in Figure 22.14 and in the animation at the URL below. Because of their shape, convex mirrors can gather and reflect light from a wide area. This is why they are used as side mirrors on cars. They give the driver a wider view of the area around the vehicle
answer:
Concave mirrors are used
question:
CC's (pronounced cee-cees) is a brand of flavoured tortilla chips produced since the early 1980s, originally by The Smith's Snackfood Company, and currently by Snack Brands Australia.
answer:
The country for CC's was what?
question:
One of China's most popular folk arts is paper cutting . Archaeological finds trace the tradition back to the 6thcentury; it is supposed that the beginnings of paper cutting were even a few centuries earlier. Paper cuttings are used for religious purposes, for decoration and as patterns . Today, paper cuttings are mainly used as decoration. They _ walls, windows, doors, columns mirrors, lamps and lanterns in homes. They are also used for decoration on presents, and are given as presents themselves. They are of special importance at festivals. At the Spring Festival for example, entrances are decorated with paper cuttings which are supposed to bring good luck. Paper cuttings are not produced by machine, but by hand. There are two kinds of paper cuttings; scissor cuttings and knife cuttings. Scissor cuttings are fashioned with scissors. Several pieces of paper--- up to eight pieces---are fastened together. The motif is then cut with sharp, pointed scissors. Knife cuttings are fashioned by putting several layers of paper on a relatively soft foundation consisting of a mixture of tallow and ashes. Following a pattern, the artist cuts the motif into the paper with a sharp knife which he usually holds vertically . The advantage of knife cuttings is that considerably more paper cuttings can be made in one operation than scissor cuttings. In the countryside, paper cuttings are usually made only by women and girls. This used to be one of the skills that every girl was to master and that were often used to judge brides . Professional paper cutting artists are, on the other hand, almost always men who have guaranteed incomes and work together in workshops.
answer:
|
Which is the best title of this passage?
| 9
|
NIv2
|
task470_mrqa_question_generation
|
fs_opt
|
Given a context passage, generate a question from the passage such that its answer is shortest continous span from the passage.
--------
Question: Chediak-Higashi syndrome (CHS) is a rare multiorgan disease entity with autosomal recessive inheritance characterized by oculocutaneous albinism, bleeding tendency, recurrent bacterial infections and various neurological symptoms. Intracellular vesicle formation is deficient, resulting in giant granules in many cells, e.g. giant melanosomes in the melanocytes. Diagnosis has been based on morphological examination of peripheral blood and bone marrow, with giant granules seen in cells of the myeloid lineage and in lymphocytes. The ultimate diagnostic test is to look for a mutated LYST gene. Most patients develop an accelerated phase of the disease with deposition of lymphohistiocytes in the liver, spleen, lymph nodes and bone marrow, resulting in hepatosplenomegaly, bone marrow infiltration and haemophagocytosis. Peripheral blood neutropenia becomes more profound as anaemia and thrombocytopenia develop. Most patients succumb before the age of 10 years. Four patients with CHS are described, one of whom is a long-term survivor after successful allogeneic bone marrow transplantation, two succumbed during the accelerated phase and one is living with a chronic form of the disease. Allogeneic bone marrow transplantation from an HLA-matched sibling is the therapy of choice and should be performed early. If there is no matched family donor, an unrelated donor or a placental blood graft is a good alternative. The clinical picture of CHS is heterogeneous and therapeutic decisions need to be made on an individual basis.
Answer: Which mutated gene causes the Chédiak–Higashi Syndrome?
Question: Neurofibromatosis type 1 (NF1) is a neurocutaneous disorder resulting in the growth of a variety of tumours, and is inherited in an autosomal dominant pattern. Gastrointestinal stromal tumours (GISTs) are mesenchymal tumours that commonly harbour oncogenic mutations in KIT or PDGFRA and are thought to arise from the interstitial cells of Cajal (ICC; the pacemaker cells of the gut). To characterise two patients with NF1 and GISTs. Two patients were genotyped for germline mutations in NF1. GISTs from both patients were genotyped for somatic mutations in KIT and PDGFRA. Loss of heterozygosity (LOH) of NF1 in one GIST was assessed by genotyping seven microsatellite markers spanning 2.39 Mb of the NF1 locus in the tumour and in genomic DNA. The known germline mutation in NF1 was confirmed in GIST DNA by sequencing. The copy number of the mutated NF1 allele was determined by multiplex ligand-dependent probe amplification. GISTs from both patients were of wild type for mutations in KIT and PDGFRA. In the GIST with adequate DNA, all seven markers were informative and showed LOH at the NF1 locus; sequencing of NF1 from that GIST showed no wild-type sequence, suggesting that it was lost in the tumour. Multiplex ligand-dependent probe amplification analysis showed that two copies of all NF1 exons were present. This is the first evidence of mitotic recombination resulting in a reduction to homozygosity of a germline NF1 mutation in an NF1-associated GIST. We hypothesise that the LOH of NF1 and lack of KIT and PDGFRA mutations are evidence of an alternative pathogenesis in NF1-associated GISTs.
Answer: Which is the gene mutated in type 1 neurofibromatosis?
Question: The Stadio Olimpico is the home of San Marino Calcio in Serravalle and was constructed in 1969.
Answer:
|
What stadium was San Marino Calcio?
| 7
|
NIv2
|
task470_mrqa_question_generation
|
fs_opt
|
Given a context passage, generate a question from the passage such that its answer is shortest continous span from the passage.
One example is below.
Q: In 1582 the united provinces invited francis, duke of anjou to lead them; but after a failed attempt to take antwerp in 1583, the duke left the netherlands again. after the assassination of william of orange (10 july 1584), both henry iii of france and elizabeth i of england declined the offer of sovereignty. however, the latter agreed to turn the united provinces into a protectorate of england (treaty of nonsuch, 1585), and sent the earl of leicester as governor-general. this was unsuccessful and in 1588 the provinces became a confederacy. the union of utrecht is regarded as the foundation of the republic of the seven united provinces, which was not recognized by the spanish empire until the peace of westphalia in 1648.
A: In what year did francis, duke of anjou leave the netherlands?
Rationale: The generated question is perfect. Because the question is based on second sentence of the input passage and its answer is 1583.
Q: Aging research in vertebrates is hampered by the lack of short-lived models. Annual fishes of the genus Nothobranchius live in East African seasonal ponds. Their life expectancy in the wild is limited by the duration of the wet season and their lifespan in captivity is also short. Nothobranchius are popular aquarium fishes and many different species are kept as captive strains, providing rich material for comparative studies. The present paper aims at reviving the interest in these fishes by reporting that: (1) Nothobranchius can be cultured, and their eggs stored dry at room temperature for months or years, offering inexpensive methods of embryo storage; (2) Nothobranchius show accelerated growth and expression of aging biomarkers at the level of histology and behaviour; (3) the species Nothobranchius furzeri has a maximum lifespan of only 3 months and offers the possibility to perform investigations thus far unthinkable in a vertebrate, such as drug screening with life-long pharmacological treatments and experimental evolution; (4) when the lifespan of different species is compared, a general correlation is found between wet season duration in their natural habitat and longevity in captivity; and (5) vertebrate aging-related genes, such as p66Shc and MTP, can be easily isolated in Nothobranchius by homology cloning. These fishes can become excellent models for aging studies. They can be employed to test the effects of experimental manipulation on aging at a pace comparable with that of Drosophila and to probe the effects of natural selection on the evolution of aging-related genes.
A:
|
What can Nothobranchius furzeri be used as a model system for?
| 9
|
NIv2
|
task470_mrqa_question_generation
|
fs_opt
|
Given a context passage, generate a question from the passage such that its answer is shortest continous span from the passage.
Example Input: Riociguat (Adempas(®)), an oral first-in-class soluble guanylate cyclase (sGC) stimulator, is under global development by Bayer Healthcare Pharmaceuticals Inc. for the treatment of adult patients with inoperable or chronic/persistent chronic thromboembolic pulmonary hypertension (CTEPH) and for the treatment of adult patients with pulmonary arterial hypertension (PAH). The drug directly stimulates sGC in a nitric oxide independent manner, thereby increasing the sensitivity of sGC to nitric oxide, leading to increased cyclic guanosine monophosphate generation (a key signalling molecule involved in regulating vascular tone, proliferation, fibrosis and inflammation). Riociguat is the world's first approved pharmacotherapy for CTEPH, with its first global approval in this indication occurring in Canada. It has subsequently been approved in the USA for the treatment of patients with CTEPH and also received its first global approval in patients with PAH in the USA. It is undergoing regulatory review for these indications in Europe and for use in patients with CTEPH in Japan. This article summarizes the milestones in the development of riociguat, leading to its first global approvals in patients with CTEPH and PAH.
Example Output: What is generic name of drug Adempas?
Example Input: Once acquired, Epstein-Barr virus (EBV), a latent virus, remains in the body for what appears to be the lifetime of the human host. Circumstantial data suggest EBV is involved in clinical disease including malignancies far more often than previously recognized. A serologic test for early antigen (EA) is more specific for diagnosing active EBV disease than the monospot or heterophile test. A case study of active Epstein-Barr infection is reported showing persistently elevated early antigen titers prior to and following malignant transformation.
Example Output: Which virus can be diagnosed with the monospot test?
Example Input: Jordan Hitch is an American business executive, and currently serves as the managing director at Bain Capital Private Equity and Bain Capital, LLC. He holds a B.S. in Mechanical Engineering from Lehigh University; and an M.B.A., with distinction, from the University of Chicago Graduate School of Business.
Example Output:
|
What is the name university that educated Jordan Hitch?
| 3
|
NIv2
|
task470_mrqa_question_generation
|
fs_opt
|
Given a context passage, generate a question from the passage such that its answer is shortest continous span from the passage.
Example Input: The Bacillus anthracis toxin genes, cya, lef, and pag, can be viewed as a regulon, in which transcription of all three genes is activated in trans by the same regulatory gene, atxA, in response to the same signal, CO2. In atxA+ strains, toxin gene expression is increased 5- to 20-fold in cells grown in 5% CO2 relative to cells grown in air. CO2-enhanced toxin gene transcription is not observed in atx4-null mutants. Here, we used two independent techniques to obtain evidence for additional CO2-induced atxA-regulated genes. First, total protein preparations from atxA4+ and atxA isolates grown in 5% CO2 and in air were examined by two-dimensional electrophoresis. Comparison of the resulting protein patterns indicated that synthesis of non-toxin proteins is influenced by growth in elevated CO2 and the toxin gene regulator, atxA. Second, we generated random transcriptional lacZ fusions in B. anthracis with transposon Tn917-LTV3. Transposon-insertion libraries were screened for mutants expressing CO2-enhanced atxA-dependent beta-galactosidase activity. DNA sequence analysis of transposon insertion sites in 17 mutants carrying CO2- and atxA-regulated fusions revealed 10 mutants carrying independent insertions on the 185-kb toxin plasmid pXO1 which did not map to the toxin genes. The tcr-lacZ fusion mutants (tcr for toxin coregulated) were Tox+, indicating that these genes may not be involved in anthrax toxin gene activation. Our data indicate a clear association of atxA with CO2-enhanced gene expression in B. anthracis and provide evidence that atxA regulates genes other than the structural genes for the anthrax toxin proteins.
Example Output: Which metabolite activates AtxA?
Example Input: Energy from the Sun comes from the lightest element, hydrogen, fusing together to create the second lightest element, helium. Nuclear fusion on the Sun releases tremendous amounts of solar energy. The energy travels to the Earth, mostly as visible light. The light carries the energy through the empty space between the Sun and the Earth as radiation. Solar energy has been used for power on a small scale for hundreds of years, and plants have used it for billions of years. Unlike energy from fossil fuels, which almost always come from a central power plant or refinery, solar power can be harnessed locally (Figure 1.1). A set of solar panels on a homes rooftop can be used to heat water for a swimming pool or can provide electricity to the house. Societys use of solar power on a larger scale is just starting to increase. Scientists and engineers have very active, ongoing research into new ways to harness energy from the Sun more efficiently. Because of the tremendous amount of incoming sunlight, solar power is being developed in the United States in southeastern California, Nevada, and Arizona. Solar panels supply power to the Interna- tional Space Station. Solar power plants turn sunlight into electricity using a large group of mirrors to focus sunlight on one place, called a receiver (Figure 1.2). A liquid, such as oil or water, flows through this receiver and is heated to a high temperature by the focused sunlight. The heated liquid transfers its heat to a nearby object that is at a lower temperature through a process called conduction. The energy conducted by the heated liquid is used to make electricity. This solar power plant uses mirrors to focus sunlight on the tower in the center. The sunlight heats a liquid inside the tower to a very high temperature, producing energy to make electricity. Solar energy has many benefits. It is extremely abundant, widespread, and will never run out. But there are problems with the widespread use of solar power. Sunlight must be present. Solar power is not useful in locations that are often cloudy or dark. However, storage technology is being developed. The technology needed for solar power is still expensive. An increase in interested customers will provide incentive for companies to research and develop new technologies and to figure out how to mass-produce existing technologies (Figure 1.3). Solar panels require a lot of space. Fortunately, solar panels can be placed on any rooftop to supply at least some of the power required for a home or business. This experimental car is one example of the many uses that engineers have found for solar energy. Click image to the left or use the URL below. URL: Click image to the left or use the URL below. URL:
Example Output: the source of solar power is nuclear
Example Input: Instituto de Administracao de Projetos Educacionais Futebol Clube play their home games at Estadio Nhozinho Santos.
Example Output:
|
The Instituto de Administração de Projetos Educacionais Futebol Clube played home games where?
| 3
|
NIv2
|
task470_mrqa_question_generation
|
fs_opt
|
Given a context passage, generate a question from the passage such that its answer is shortest continous span from the passage.
--------
Question: The conserved histone variant H2A.Z functions in euchromatin to antagonize the spread of heterochromatin. The mechanism by which histone H2A is replaced by H2A.Z in the nucleosome is unknown. We identified a complex containing 13 different polypeptides associated with a soluble pool of H2A.Z in Saccharomyces cerevisiae. This complex was designated SWR1-Com in reference to the Swr1p subunit, a Swi2/Snf2-paralog. Swr1p and six other subunits were found only in SWR1-Com, whereas six other subunits were also found in the NuA4 histone acetyltransferase and/or the Ino80 chromatin remodeling complex. H2A.Z and SWR1 were essential for viability of cells lacking the EAF1 component of NuA4, pointing to a close functional connection between these two complexes. Strikingly, chromatin immunoprecipitation analysis of cells lacking Swr1p, the presumed ATPase of the complex, revealed a profound defect in the deposition of H2A.Z at euchromatic regions that flank the silent mating type cassette HMR and at 12 other chromosomal sites tested. Consistent with a specialized role for Swr1p in H2A.Z deposition, the majority of the genome-wide transcriptional defects seen in swr1Delta cells were also found in htz1Delta cells. These studies revealed a novel role for a member of the ATP-dependent chromatin remodeling enzyme family in determining the region-specific histone subunit composition of chromatin in vivo and controlling the epigenetic state of chromatin. Metazoan orthologs of Swr1p (Drosophila Domino; human SRCAP and p400) may have analogous functions.
Answer: Which protein mediates the replacement of H2A by H2A.Z in the yeast Saccharomyces cerevisiae?
Question: Throughout 1476, supporters of Joanna from the nobility continued to submit to Isabella and Ferdinand, particularly those from the Pacheco-Giron lineage: Juan Tellez-Giron and his brother Rodrigo; Luis de Portocarrero; and, in September, the Marquis of Villena. In November 1476, Isabella's troops captured the castle of Toro. In the following months, they took control of the last bordering localities controlled by the Portuguese and dealt with their adversaries in Extremadura. In July 1477, Isabella arrived in Seville, the most populous city of Castile, with the objective of asserting her power over the nobility of Andalusia. In April 1476, Isabella and Ferdinand gave their first exculpation to the Marquis of Cadiz. He had been regaining power while his rival, the Duke of Medina Sidonia, initially the main Isabella supporter in Andalusia, had been falling into dishonour. Through skilful negotiations, the Queen managed to take control of the main strongholds of Seville occupied by the Marquis and the Duke and, instead of returning them to their legitimate owners, named others as their heads. She prohibited both nobles from entering the city of Seville, under the pretext that their simultaneous presence there would risk violent conflicts. In this way the Duke's political dominance over Seville disappeared, and the city passed into the control of the Crown. One of the few nobles that refused to submit to the monarchs was Marshall Fernan Arias de Saavedra. Isabella's troops laid siege to his fortress at Utrera, and conquered it by assault in March 1478. The defeated suffered harsh repression. The first son of the monarchs, John of Aragon and Castile, was born in Seville on June 30, 1478, which opened new possibilities for dynastic stability of the Isabellian side.
Answer: What event happened first, Isabella arriving in Seville or Isabella and Ferdinand giving their first exculpation to the Marquis of Cadiz?
Question: Biologists agree that the ancestor of mitochondria was an alpha-proteobacterium. But there is no consensus as to what constitutes an alpha-proteobacterial gene. Is it a gene found in all or several alpha-proteobacteria, or in only one? Here, we examine the proportion of alpha-proteobacterial genes in alpha-proteobacterial genomes by means of sequence comparisons. We find that each alpha-proteobacterium harbours a particular collection of genes and that, depending upon the lineage examined, between 97 and 33% are alpha-proteobacterial by the nearest-neighbour criterion. Our findings bear upon attempts to reconstruct the mitochondrial ancestor and upon inferences concerning the collection of genes that the mitochondrial ancestor possessed at the time that it became an endosymbiont.
Answer:
|
Which species of bacteria did the mitochondria originate from?
| 7
|
NIv2
|
task470_mrqa_question_generation
|
fs_opt
|
Given a context passage, generate a question from the passage such that its answer is shortest continous span from the passage.
Let me give you an example: In 1582 the united provinces invited francis, duke of anjou to lead them; but after a failed attempt to take antwerp in 1583, the duke left the netherlands again. after the assassination of william of orange (10 july 1584), both henry iii of france and elizabeth i of england declined the offer of sovereignty. however, the latter agreed to turn the united provinces into a protectorate of england (treaty of nonsuch, 1585), and sent the earl of leicester as governor-general. this was unsuccessful and in 1588 the provinces became a confederacy. the union of utrecht is regarded as the foundation of the republic of the seven united provinces, which was not recognized by the spanish empire until the peace of westphalia in 1648.
The answer to this example can be: In what year did francis, duke of anjou leave the netherlands?
Here is why: The generated question is perfect. Because the question is based on second sentence of the input passage and its answer is 1583.
OK. solve this:
Jordan Hitch is an American business executive, and currently serves as the managing director at Bain Capital Private Equity and Bain Capital, LLC. He holds a B.S. in Mechanical Engineering from Lehigh University; and an M.B.A., with distinction, from the University of Chicago Graduate School of Business.
Answer:
|
What is the name university that educated Jordan Hitch?
| 8
|
NIv2
|
task470_mrqa_question_generation
|
fs_opt
|
Given a context passage, generate a question from the passage such that its answer is shortest continous span from the passage.
One example: In 1582 the united provinces invited francis, duke of anjou to lead them; but after a failed attempt to take antwerp in 1583, the duke left the netherlands again. after the assassination of william of orange (10 july 1584), both henry iii of france and elizabeth i of england declined the offer of sovereignty. however, the latter agreed to turn the united provinces into a protectorate of england (treaty of nonsuch, 1585), and sent the earl of leicester as governor-general. this was unsuccessful and in 1588 the provinces became a confederacy. the union of utrecht is regarded as the foundation of the republic of the seven united provinces, which was not recognized by the spanish empire until the peace of westphalia in 1648.
Solution is here: In what year did francis, duke of anjou leave the netherlands?
Explanation: The generated question is perfect. Because the question is based on second sentence of the input passage and its answer is 1583.
Now, solve this: Restless Legs Syndrome (RLS) or Willis-Ekbom Disease (WED) is highly prevalent, but patients and healthcare providers alike know little about it. Furthermore, controversy persists as to the best way of diagnosing this nosological entity. To verify whether the term used to refer to this disease entity (Restless Legs Syndrome or Willis-Ekbom Disease) affects the prevalence of self-diagnosed RLS/WED in a sample of newly graduated physicians. Newly graduated physicians were asked to self-evaluate for the presence of RLS/WED. Briefly, participants were allocated randomly across two groups. One was asked to self-assess for RLS, while the other was asked to self-assess for WED. The evaluation form given to one group asked 'Do you have Restless Legs Syndrome?' whereas the form given to participants in the other group asked 'Do you have Willis-Ekbom Disease?'. Both forms also contained the four criteria for diagnosing RLS proposed by the International Restless Legs Syndrome Study Group (IRLSSG) and instructions for self-diagnosis according to these criteria. The study sample comprised 1413 newly graduated physicians. Of the 708 participants who were given the form that used the term RLS, 87 (12.28%) diagnosed themselves with the condition. Conversely, of 705 physicians given the form with the term WED, 13 (1.84%) diagnosed themselves with the condition (p<0.0001). A greater proportion of newly graduated physicians diagnosed themselves with RLS/WED when presented with the term Restless Legs Syndrome than when presented with the term Willis-Ekbom Disease. This suggests that the term Restless Legs Syndrome may not be the most appropriate term to denote this nosological entity.
Solution:
|
Willis-Ekbom disease is also known as?
| 6
|
NIv2
|
task470_mrqa_question_generation
|
fs_opt
|
Given a context passage, generate a question from the passage such that its answer is shortest continous span from the passage.
Q: Leke III Dukagjini (1410--1481), mostly known as Leke Dukagjini, was a mysterious member of the Dukagjini family about whom little is known and who is thought to have been a 15th-century Albanian nobleman.
A: What was the noble family that Lekë Dukagjini was from?
****
Q: Malaria, which is the result of Plasmodium falciparum infection, is a global health threat that resulted in 655,000 deaths and 216 million clinical cases in 2010 alone. Recent phase 3 trials with malaria vaccine candidate RTS,S/AS01 (RTS,S) in children has demonstrated modest efficacy against clinical and severe malaria. RTS,S targets the pre-erythrocytic phase of the disease and induces high antibody titers against the P. falciparum circumsporozoite protein (CSP) and a moderate CD4(+) T cell response. The individual contribution of these adaptive immune responses to protection from infection remains unknown. Here, we found that prophylactic administration of anti-CSP mAbs derived from an RTS,S-vaccinated recipient fully protected mice with humanized livers from i.v.- and mosquito bitedelivered P. falciparum sporozoite challenge. Titers of anti-CSP that conveyed full protection were within the range observed in human RTS,S vaccine recipients. Increasing anti-CSP titers resulted in a dose-dependent reduction of the liver parasite burden. These data indicate that RTS,S-induced antibodies are protective and provide sterilizing immunity against P. falciparum infection when reaching or exceeding a critical plasma concentration.
A: RTS S AS01 vaccine was developed to prevent which disease?
****
Q: Restless Legs Syndrome (RLS) or Willis-Ekbom Disease (WED) is highly prevalent, but patients and healthcare providers alike know little about it. Furthermore, controversy persists as to the best way of diagnosing this nosological entity. To verify whether the term used to refer to this disease entity (Restless Legs Syndrome or Willis-Ekbom Disease) affects the prevalence of self-diagnosed RLS/WED in a sample of newly graduated physicians. Newly graduated physicians were asked to self-evaluate for the presence of RLS/WED. Briefly, participants were allocated randomly across two groups. One was asked to self-assess for RLS, while the other was asked to self-assess for WED. The evaluation form given to one group asked 'Do you have Restless Legs Syndrome?' whereas the form given to participants in the other group asked 'Do you have Willis-Ekbom Disease?'. Both forms also contained the four criteria for diagnosing RLS proposed by the International Restless Legs Syndrome Study Group (IRLSSG) and instructions for self-diagnosis according to these criteria. The study sample comprised 1413 newly graduated physicians. Of the 708 participants who were given the form that used the term RLS, 87 (12.28%) diagnosed themselves with the condition. Conversely, of 705 physicians given the form with the term WED, 13 (1.84%) diagnosed themselves with the condition (p<0.0001). A greater proportion of newly graduated physicians diagnosed themselves with RLS/WED when presented with the term Restless Legs Syndrome than when presented with the term Willis-Ekbom Disease. This suggests that the term Restless Legs Syndrome may not be the most appropriate term to denote this nosological entity.
A:
|
Willis-Ekbom disease is also known as?
****
| 4
|
NIv2
|
task470_mrqa_question_generation
|
fs_opt
|
Given a context passage, generate a question from the passage such that its answer is shortest continous span from the passage.
[Q]: German academics believe they have solved the centuries-old mystery of the "Mona Lisa" in Leonardo ad Vinci's famous portrait . Lisa Gherardini, the wife of a wealthy Florentine merchant, Francesco del Giocondo, has long been seen as the most likely model for the sixteenth-century painting. Art historians have wondered whether the smiling woman may actually have been da Vinci's lover or mother, or the artist himself. Now experts at the prefix = st1 /HeidelbergUniversitylibrary say old notes made in a book by its owner in October, 1503, confirm that Lisa del Giocondo was indeed the model for the famous portrait in the world. "All doubts about the identity of the Mona Lisa have been removed by a discovery by Dr. Armin Schlechter," the library said in a statement on Monday. "Until then, only 'scant evidence' from sixteenth-century documents had been available. These had left lots of room for doubt, and many different identities were put forward." The comments compare Leonardo to the ancient Greek artist Apelles, and say he was working on three paintings at that time, one of which was a portrait of Lisa del Giocondo. Art experts say the Heidelbergdiscovery is a break-through, and the earliest mention linking the merchant's wife to the portrait. Before this discovery the earliest link dated from around 1550, and was made by Italian official Giorgio Vasari, the library said, adding that there had been doubts about Vasari's reliability. The Heidelbergnotes were actually discovered over two year's ago in the library by Schlechter, a spokeswoman said. Although the findings were published in the library's catalogue, they were not widely publicized, and received little attention until a German broadcaster decided to do some recording there, she said.
[A]: Who discovered the Heidelbergnotes?
[Q]: Fish species are expected to shrink in size by up to 24% because of global warming, say scientists. The scientists argue that failure to control greenhouse gas emissions will have a greater effect on marine ecosystems than previously thought. Previous research has suggested that changing ocean temperatures would affect both the distribution and the reproductive abilities of many species of fish. This new work suggests that fish size would also be heavily affected. The researchers built a model to see how fish would react to lower levels of oxygen in the water. As ocean temperatures increase, so do the body temperatures of fish. But, according to lead author, Dr William Cheung, from the University of British Columbia, the lower level of oxygen in the water is key. Warmer waters could decrease ocean oxygen levels and greatly reduce fish body weight. On the other hand, rising temperatures directly increase the metabolic rate of the fish's body function. This leads to an increase in oxygen demand for normal body activities. So the fish will run out of oxygen for growth at a smaller body size. The research team also used its model to predict fish movements as a result of warming waters. The group believes that most fish populations will move towards the Earth's poles at a rate of up to 35km per decade. "So in, say, the North Sea," says Dr Cheung," one would expect to see more smaller-body fish from tropical waters in the future." Taking these factors into consideration, the research team concludes that fish body size will shrink between 14% and 24%, with the largest decreases in the Indian and Atlantic oceans. When compared with actual observations of fish sizes, the model seems to _ what's actually happening in the seas. The researchers looked at two case studies involving North Atlantic cod and haddock. They found that recorded data on these fish showed greater decreases in body size than the models had predicted. Dr Alan Baudron, from the University of Aberdeen, UK, believes smaller-sized fish could seriously affect the ability of fish to reproduce. "Smaller fish produce fewer and smaller eggs which could affect the reproductive potential of fish stocks," he said.
[A]: What is the key factor making the fish smaller now?
[Q]: The Packers were trailing the winless Cleveland Browns 14-7 in the third quarter. The Browns scored a touchdown to make it 21-7, but Hundley and the Packers responded with a touchdown drive of their own, making it 21-14. The Packers tied the game with 17 seconds left on a touchdown pass to Davante Adams. In overtime, Browns quarterback DeShone Kizer threw a costly interception to Josh Jones, and Adams took a screen pass to the end zone, improving the Packers record to 7-6 and setting the stage for Aaron Rodgers' comeback.
[A]:
|
Who was winning in the 3rd quarter?
| 5
|
NIv2
|
task470_mrqa_question_generation
|
fs_opt
|
Teacher: Given a context passage, generate a question from the passage such that its answer is shortest continous span from the passage.
Teacher: Now, understand the problem? If you are still confused, see the following example:
In 1582 the united provinces invited francis, duke of anjou to lead them; but after a failed attempt to take antwerp in 1583, the duke left the netherlands again. after the assassination of william of orange (10 july 1584), both henry iii of france and elizabeth i of england declined the offer of sovereignty. however, the latter agreed to turn the united provinces into a protectorate of england (treaty of nonsuch, 1585), and sent the earl of leicester as governor-general. this was unsuccessful and in 1588 the provinces became a confederacy. the union of utrecht is regarded as the foundation of the republic of the seven united provinces, which was not recognized by the spanish empire until the peace of westphalia in 1648.
Solution: In what year did francis, duke of anjou leave the netherlands?
Reason: The generated question is perfect. Because the question is based on second sentence of the input passage and its answer is 1583.
Now, solve this instance: A central feature of Alzheimer's disease is the cleavage of the amyloid precursor protein (APP) to form beta-amyloid peptide (Abeta) by the beta-secretase and gamma-secretase enzymes. Although this has been shown to occur after endocytosis of APP from the cell surface, the exact compartments of APP processing are not well defined. We have previously demonstrated that APP and gamma-secretase proteins and activity are highly enriched in purified rat liver lysosomes. In order to examine the lysosomal distribution and trafficking of APP in cultured cells, we generated constructs containing APP fused to a C-terminal fluorescent protein tag and N-terminal HA-epitope tag. These were co-transfected with a panel of fluorescent-protein tagged compartment markers. Here we demonstrate using laser-scanning confocal microscopy that although APP is present throughout the endosomal/lysosomal system in transfected Cos7 and neuronal SN56 cell lines as well as in immunostained cultured mouse neurons, it is enriched in the lysosome. We also show that the Swedish and London mutations reduce the amount of APP in the lysosome. Surprisingly, in addition to its expected trafficking from the cell surface to the early and then late endosomes, we find that cell-surface labelled APP is transported rapidly and directly from the cell surface to lysosomes in both Cos7 and SN56 cells. This rapid transit to the lysosome is blocked by the presence of either the London or Swedish mutations. These results demonstrate the presence of a novel, rapid and specific transport pathway from the cell surface to the lysosomes. This suggests that regulation of lysosomal traffic could regulate APP processing and that the lysosome could play a central role in the pathophysiology of Alzheimer's disease.
Student:
|
Which disease the London mutation involved in?
| 2
|
NIv2
|
task470_mrqa_question_generation
|
fs_opt
|
Given a context passage, generate a question from the passage such that its answer is shortest continous span from the passage.
Example: In 1582 the united provinces invited francis, duke of anjou to lead them; but after a failed attempt to take antwerp in 1583, the duke left the netherlands again. after the assassination of william of orange (10 july 1584), both henry iii of france and elizabeth i of england declined the offer of sovereignty. however, the latter agreed to turn the united provinces into a protectorate of england (treaty of nonsuch, 1585), and sent the earl of leicester as governor-general. this was unsuccessful and in 1588 the provinces became a confederacy. the union of utrecht is regarded as the foundation of the republic of the seven united provinces, which was not recognized by the spanish empire until the peace of westphalia in 1648.
Example solution: In what year did francis, duke of anjou leave the netherlands?
Example explanation: The generated question is perfect. Because the question is based on second sentence of the input passage and its answer is 1583.
Problem: Chronic myeloid leukemia (CML) is caused by Bcr-Abl, a constitutively active tyrosine kinase that is the result of a reciprocal translocation between chromosomes 9 and 22 and cytogenetically evident as the Philadelphia chromosome. Imatinib (Glivec, Gleevec), a specific small molecule inhibitor of Bcr-Abl, has become the standard drug therapy for CML, and has dramatically diminished the use of allogeneic stem cell transplantation. Despite unprecedented rates of complete cytogenetic response, residual disease remains detectable in the majority of patients, suggesting that imatinib fails to eradicate leukemic stem cells. In this publication, the current perspectives for CML patients treated with imatinib are reviewed, focusing on the results of both standard and high-dose therapy. Monitoring of time-dependent prognostic factors is reviewed. The reasons imatinib may not be able to eradicate the disease are discussed, and potential strategies to achieve disease elimination are presented. Lastly, resistance to imatinib and the potential of second-generation Abl kinase inhibitors in the setting of clinical resistance are considered.
|
Solution: What tyrosine kinase, involved in a Philadelphia- chromosome positive chronic myelogenous leukemia, is the target of Imatinib (Gleevec)?
| 5
|
NIv2
|
task470_mrqa_question_generation
|
fs_opt
|
You will be given a definition of a task first, then an example. Follow the example to solve a new instance of the task.
Given a context passage, generate a question from the passage such that its answer is shortest continous span from the passage.
In 1582 the united provinces invited francis, duke of anjou to lead them; but after a failed attempt to take antwerp in 1583, the duke left the netherlands again. after the assassination of william of orange (10 july 1584), both henry iii of france and elizabeth i of england declined the offer of sovereignty. however, the latter agreed to turn the united provinces into a protectorate of england (treaty of nonsuch, 1585), and sent the earl of leicester as governor-general. this was unsuccessful and in 1588 the provinces became a confederacy. the union of utrecht is regarded as the foundation of the republic of the seven united provinces, which was not recognized by the spanish empire until the peace of westphalia in 1648.
Solution: In what year did francis, duke of anjou leave the netherlands?
Why? The generated question is perfect. Because the question is based on second sentence of the input passage and its answer is 1583.
New input: According to a new US study, couples who expect their children to help care for them in old age should hope they have daughters because they are likely to be twice as attentive overall. The research by Angelina Grigoryeva, a sociologist at Princeton University, found that, while women provide as much care for their elderly parents as they can manage, men do as little as they can get away with and often leave it to female family members. Her analysis of the family networks of 26,000 older Americans concluded that gender is the most important predictor of whether or not people will actively care for elderly parents. In a paper being presented at the annual conference of the American Sociological Association in San Francisco, she concludes that simply having a sister makes men statistically likely provide less care. Using data from the University of Michigan Health and Retirement Study, a study which has been tracking a cross-section of over-50s for the last decade, she calculated that women provide an average of 12.3 hours a month of care for elderly parents while men offer only 5.6 hours. "Whereas the amount of elderly parent care daughters provide is associated with limitations they face, such as employment or childcare, sons'caregiving is associated only with the presence or absence of other helpers, such as sisters or a parent's spouse ," she explained. "Sons reduce their relative caregiving efforts when they have a sister, while daughters increase theirs when they have a brother." "This suggests that sons pass on parent caregiving responsibilities to their sisters." In the UK, the 2011 census showed that there are now around 6.5 million people with caring responsibilities - a figure which has risen by a tenth in a decade. But many are doing so at the risk of their own health. The census showed that those who provide 50 hours or more of care a week while trying to hold down a full- time job are three times more likely to be struggling with ill health than their working counterparts who are not carers.
Solution:
|
What's the most important factor to predict if people will actively care for the elderly?
| 0
|
NIv2
|
task470_mrqa_question_generation
|
fs_opt
|
Given a context passage, generate a question from the passage such that its answer is shortest continous span from the passage.
One example: In 1582 the united provinces invited francis, duke of anjou to lead them; but after a failed attempt to take antwerp in 1583, the duke left the netherlands again. after the assassination of william of orange (10 july 1584), both henry iii of france and elizabeth i of england declined the offer of sovereignty. however, the latter agreed to turn the united provinces into a protectorate of england (treaty of nonsuch, 1585), and sent the earl of leicester as governor-general. this was unsuccessful and in 1588 the provinces became a confederacy. the union of utrecht is regarded as the foundation of the republic of the seven united provinces, which was not recognized by the spanish empire until the peace of westphalia in 1648.
Solution is here: In what year did francis, duke of anjou leave the netherlands?
Explanation: The generated question is perfect. Because the question is based on second sentence of the input passage and its answer is 1583.
Now, solve this: APOA4 resides on chromosome 11 in close linkage to APOA1 and APOC3.
Solution:
|
Which chromosome is related with APOA4?
| 6
|
NIv2
|
task470_mrqa_question_generation
|
fs_opt
|
Given a context passage, generate a question from the passage such that its answer is shortest continous span from the passage.
Q: The Web site for the Anxiety Disorders Association of America (ADAA) receives more than 5 million visits per month and thus represents a unique medium for the study of anxiety disorders. ADAA Web site users from October 2002 to January 2003 were invited to complete a survey oriented toward trauma history and psychiatric sequelae. A diagnostic approximation of posttraumatic stress disorder (PTSD) was based on responses to the Trauma Questionnaire, the Davidson Trauma Scale, and questions about impairment. The Connor-Davidson Resilience Scale was also used. Variables were tested for their association with PTSD. Among 1558 participants, 87% had a history of trauma, and 38% had current PTSD. The population was comprised predominantly of white middle-class women, half of whom were married. More than 90% were first-time users of the site. Factors associated with PTSD included death of, or harm to, a loved one; personal history of incest, rape, or physical abuse; lower age; lower income; unemployment; missed work; increased medical care; dissatisfaction with psychotropic medication; depressive symptoms; and lower resilience. In this selective convenience sample, there were high rates of traumatization and PTSD. The demographics of this group are similar to those seen in previously studied populations that had contacted the ADAA. Furthermore, the factors associated with PTSD were like those in many community surveys. The ADAA Web site has the opportunity to benefit large numbers of highly distressed individuals.
A: Symptoms of which disorder are evaluated with the Davidson Trauma Scale?
****
Q: Contrary to earlier beliefs, viruses are not the smallest causative agents of infectious diseases. Single-stranded RNAs as small as 246 nucleotides exist in certain higher plants and cause more than a dozen crop diseases. These RNAs have been termed viroids. Despite their extremely limited information content, viroids replicate autonomously in susceptible cells--that is, they do not require helper functions from simultaneously replicating conventional viruses. Viroids are covalently closed circular molecules with a characteristic rodlike secondary structure in which short helical regions are interrupted by internal and bulge loops. Viroids are not translated; they are replicated by a host enzyme (or enzymes) (probably RNA polymerase II) via oligomeric RNA intermediates by a rolling circle mechanism. Viroidlike satellite RNAs resemble viroids in size and molecular structure, but are found within the capsids of specific helper viruses on which they depend for their own replication. These RNAs are of great interest to molecular biology for at least two reasons: 1) they are the smallest and simplest replicating molecules known, and 2) they may represent living fossils of precellular evolution in a hypothetical RNA world.
A: Which are the smallest known subviral pathogens of plants?
****
Q: Chronic myeloid leukemia (CML) is caused by Bcr-Abl, a constitutively active tyrosine kinase that is the result of a reciprocal translocation between chromosomes 9 and 22 and cytogenetically evident as the Philadelphia chromosome. Imatinib (Glivec, Gleevec), a specific small molecule inhibitor of Bcr-Abl, has become the standard drug therapy for CML, and has dramatically diminished the use of allogeneic stem cell transplantation. Despite unprecedented rates of complete cytogenetic response, residual disease remains detectable in the majority of patients, suggesting that imatinib fails to eradicate leukemic stem cells. In this publication, the current perspectives for CML patients treated with imatinib are reviewed, focusing on the results of both standard and high-dose therapy. Monitoring of time-dependent prognostic factors is reviewed. The reasons imatinib may not be able to eradicate the disease are discussed, and potential strategies to achieve disease elimination are presented. Lastly, resistance to imatinib and the potential of second-generation Abl kinase inhibitors in the setting of clinical resistance are considered.
A:
|
What tyrosine kinase, involved in a Philadelphia- chromosome positive chronic myelogenous leukemia, is the target of Imatinib (Gleevec)?
****
| 4
|
NIv2
|
task470_mrqa_question_generation
|
fs_opt
|
Given a context passage, generate a question from the passage such that its answer is shortest continous span from the passage.
Input: Consider Input: Anna Foster (Mandy Moore) is the daughter of the President of the United States, James (Mark Harmon) and First Lady Michelle Foster (Caroline Goodall).When a hassle of Secret Service agents ruins a first date, Anna demands some freedom. Her dad agrees to send only two agents with Anna and Gabrielle La Clare (Beatrice Rosen) to a concert when Anna goes to Prague with her parents. A sexy new look for Anna causes her father to renege. When Anna discovers the concert is filled with agents and that her father has broken his promise, Gabrielle helps Anna elude her protectors. Outside the concert, Anna meets Ben Calder (Matthew Goode), and asks him to drive her to escape the agents. Anna goes to a bar with Ben and proceeds to get drunk. Unbeknownst to Anna, Ben is with the Secret Service, and tells agents Alan Weiss (Jeremy Piven) and Cynthia Morales (Annabella Sciorra) where Anna is. The President orders the three agents to have Ben guard Anna without telling her who he really is, to give her an illusion of freedom with a guarantee of safety. Believing herself free of her guards for the first time in years, Anna jumps into the Vltava River naked, mistaking it for the Danube, and Ben has to fish her out (he stays clothed). Weiss and Morales buy the camera from someone taking pictures of the skinny-dipping Anna. Anna and Ben climb a rooftop to watch an opera being shown in a plaza, where Anna eventually falls asleep with Ben guarding her, and Weiss and Morales watching from another roof.The next morning, Anna calls her parents to avoid getting into further trouble with them. Knowing she is safe, her father is initially indulgent, and Anna is about to return, but his tone changes when he is shown the photos of her nude in the river. The First Lady, however, asks, "What happened to 'let freedom ring?'" (That had been his earlier line when he had decided to let her stay out with Ben.) Anna is outraged at both her dad's sudden imperious tone and finding out that he traced her call. She decides to meet Gabrielle at the Love Parade in Berlin and return to her parents right before the plane trip home. Ben goes with her on the train, where they meet Scotty McGruff (Martin Hancock), a flighty romantic obsessed with Six Million Dollar Man stickers and the interconnectivity of the world, he gives them a stack of stickers and tells them to stick them up in random places, then one day when they are unhappy, they will see one and it will make them smile. Through him, the two learn that they have boarded a Venice-bound train. When they arrive in Venice, Ben calls the other agents to tell them where they are but has to leave the phone dangling when he realizes he can no longer see Anna. He finds her and McGruff getting new clothes, and the three explore Venice - until McGruff steals their wallets. Ben is about to tell the cafe they cannot pay when Anna is recognized and races off to avoid being identified as the First Daughter. Ben follows, and they tell a story of marrying, against the wishes of Anna's parents, to get a gondola ride from a kind-hearted gondolier, Eugenio (Joseph Long). Ben kisses Anna during the ride to hide her from the cafe staff's sight. Since they have no place to stay, Eugenio invites them to his and his mother Maria's (Miriam Margolyes) house. That night, thinking the kiss meant that Ben cares for her, Anna offers herself to him. To dissuade her, Ben is disingenuous and harsh. Anna finally gets in the bed alone, while Ben lies on the floor.The next day, Eugenio drives them to the Austrian border, as Weiss and Morales show up at Maria's looking for the gondolier with whom Anna and Ben were last seen. Maria tells them that Anna and Ben are married, which is reported to Anna's parents. Upset that Ben rejected her, Anna gets a ride on a truck, leaving Ben to
Output: What is Anna's dad occupation?
Input: Consider Input: Mutaib bin Abdullah bin Abdulaziz Al Saud (Arabic: , Mutib bin Abd Allah bin Abd al-Aziz Al Suud, alternative spelling Miteb) (born 26 March 1952) is a member of House of Saud who has served as Saudi Arabia's Minister of the National Guard since 27 May 2013.
Output: What was the noble family that Mutaib bin Abdullah was from?
Input: Consider Input: It's a nightmare for Huazhong University of Science and Technology (HUST): within a week, two students committed suicide by jumping off dorm buildings. Officials from the university are reluctant to give interviews. "We had a hard time calming down students who were shocked at the suicides," said Zhang Jingyuan, head of HUST's center for research and guidance for students' development. "Media coverage may arouse some students' negative emotions again. Suicide can be contagious ," Zhang said. The university reacted promptly to the first suicide on October 23. Advisors and class leaders conducted dorm-to-dorm checks to find students suffering depression. Then psychologists offered one-on-one counseling to them. Notice boards publicizing tips for identifying peers' mental problems and offering help were set up in front of dorm buildings. Leaflets carrying similar information were handed out to each dorm. However, the second suicide came seven days later. Both students were described as men of few words. Their schoolmates didn't see anything to indicate suicide. Zhang revealed that the two students had been bothered by mental disorders. But the school didn't know this until the students' close friends outside school and their parents unveiled the truth after the suicides. According to Zhang, there are only three full-time counselors working in the university's counseling center for its 60,000 students. He complained: "It's unrealistic to rely only on counselors to detect students' mental problems." Some universities in the US may be able to offer solutions to Zhang's worries. They have established programs to train students to be the bridge between troubled friends and counselors. At Worcester Polytechnic Institute, at Worcester, Massachusetts, US, young people in the Student Support Network role play to learn how to detect SOS signals from their schoolmates. They also practice how to gently persuade emotionally troubled students to go for professional help. To develop such empathy , many universities in China have organized campus events to popularize knowledge about mental health. But these are not that attractive to students. Ke Juanjuan, 24, is pursuing a master's degree in English translation at HUST. Ke has found that few of her peers will pay attention to activities about mental health when they are not troubled by it. Rather than bombard students with the words "mental health", Ke suggested the school organize lectures and workshops concerning study, job-hunting and relationships. She explained: "Students care about these topics. They tend to have problems in these areas and may thus get stuck in depression. "By helping students better deal with these problems, the school can effectively prevent self-inflicted injury and suicide among students." Effective prevention comes from long-term education for life instead of temporary intervention to meet an emergency, said Hu Yi'an. Hu delivers a course of lectures on life and death at Guangzhou University. He worries that universities have paid little attention to education for life. "Education for life helps students respect and love life so they won't resort to ending their lives when they have difficulties," said Hu. According to Hu, the principles can be incorporated into everyday teaching.
|
Output: Which one of the following is NOT one of the reasons why officials from the university are reluctant to give interviews?
| 2
|
NIv2
|
task470_mrqa_question_generation
|
fs_opt
|
Given a context passage, generate a question from the passage such that its answer is shortest continous span from the passage.
[EX Q]: The SET domain contains the catalytic center of lysine methyltransferases that target the N-terminal tails of histones and regulate chromatin function. Here we report the structure of the SET7/9 protein in the absence and presence of its cofactor product, S-adenosyl-L-homocysteine (AdoHcy). A knot within the SET domain helps form the methyltransferase active site, where AdoHcy binds and lysine methylation is likely to occur. A structure-guided comparison of sequences within the SET protein family suggests that the knot substructure and active site environment are conserved features of the SET domain.
[EX A]: What is the characteristic domain of histone methyltransferases?
[EX Q]: Jacques Collin de Plancy was the father of Victor Collin de Plancy (1853--1924), who, for nearly a decade, starting in 1884, served as French Minister to Korea and whose collected art works and books became part of the core of the Korean collections of the French Bibliotheque Nationale and the Musee Guimet in Paris.
[EX A]: Who is the offspring of Jacques Collin de Plancy?
[EX Q]: Sports City Stadium is a proposed football stadium which will be built in Doha, Qatar in time for the 2022 FIFA World Cup in Qatar.
[EX A]:
|
What team uses Sports City Stadium?
| 6
|
NIv2
|
task470_mrqa_question_generation
|
fs_opt
|
Given a context passage, generate a question from the passage such that its answer is shortest continous span from the passage.
Example: In 1582 the united provinces invited francis, duke of anjou to lead them; but after a failed attempt to take antwerp in 1583, the duke left the netherlands again. after the assassination of william of orange (10 july 1584), both henry iii of france and elizabeth i of england declined the offer of sovereignty. however, the latter agreed to turn the united provinces into a protectorate of england (treaty of nonsuch, 1585), and sent the earl of leicester as governor-general. this was unsuccessful and in 1588 the provinces became a confederacy. the union of utrecht is regarded as the foundation of the republic of the seven united provinces, which was not recognized by the spanish empire until the peace of westphalia in 1648.
Example solution: In what year did francis, duke of anjou leave the netherlands?
Example explanation: The generated question is perfect. Because the question is based on second sentence of the input passage and its answer is 1583.
Problem: Minerals are everywhere! Scientists have identified more than 4,000 minerals in Earths crust, although the bulk of the planet is composed of just a few. A mineral possesses the following qualities: It must be solid. It must be crystalline, meaning it has a repeating arrangement of atoms. It must be naturally occurring. It must be inorganic. It must have a specific chemical composition. Minerals can be identified by their physical properties, such as hardness, color, luster (shininess), and odor. The most common laboratory technique used to identify a mineral is X-ray diffraction (XRD), a technique that involves shining an X-ray light on a sample, and observing how the light exiting the sample is bent. XRD is not useful in the field, however. The definition of a mineral is more restricted than you might think at first. For example, glass is made of sand, which is rich in the mineral quartz. But glass is not a mineral, because it is not crystalline. Instead, glass has a random assemblage of molecules. What about steel? Steel is made by mixing different metal minerals like iron, cobalt, chromium, vanadium, and molybdenum, but steel is not a mineral because it is made by humans and therefore is not naturally occurring. However, almost any rock you pick up is composed of minerals. Below we explore the qualities of minerals in more detail. Minerals are "crystalline" solids. A crystal is a solid in which the atoms are arranged in a regular, repeating pattern. Notice that in Figure 1.1 the green and purple spheres, representing sodium and chlorine, form a repeating pattern. In this case, they alternate in all directions. Sodium ions (purple balls) bond with chlo- ride ions (green balls) to make table salt (halite). All of the grains of salt that are in a salt shaker have this crystalline structure. Organic substances are the carbon-based compounds made by living creatures and include proteins, carbohydrates, and oils. Inorganic substances have a structure that is not characteristic of living bodies. Coal is made of plant and animal remains. Is it a mineral? Coal is a classified as a sedimentary rock, but is not a mineral. Minerals are made by natural processes, those that occur in or on Earth. A diamond created deep in Earths crust is a mineral, but a diamond made in a laboratory by humans is not. Be careful about buying a laboratory-made diamond for jewelry. It may look pretty, but its not a diamond and is not technically a mineral. Nearly all (98.5%) of Earths crust is made up of only eight elements - oxygen, silicon, aluminum, iron, calcium, sodium, potassium, and magnesium - and these are the elements that make up most minerals. All minerals have a specific chemical composition. The mineral silver is made up of only silver atoms and diamond is made only of carbon atoms, but most minerals are made up of chemical compounds. Each mineral has its own chemical formula. Table salt (also known as halite), pictured in Figure 1.1, is NaCl (sodium chloride). Quartz is always made of two oxygen atoms (red) bonded to a silicon atom (grey), represented by the chemical formula SiO2 (Figure 1.2). Quartz is made of two oxygen atoms (red) bonded to a silicon atom (grey). In nature, things are rarely as simple as in the lab, and so it should not come as a surprise that some minerals have a range of chemical compositions. One important example in Earth science is olivine, which always has silicon and oxygen as well as some iron and magnesium, (Mg, Fe)2 SiO4 . Some minerals can be identified with little more than the naked eye. We do this by examining the physical properties of the mineral in question, which include: Color: the color of the mineral. Streak: the color of the minerals powder (this is often different from the color of the whole mineral). Luster: shininess. Density: mass per volume, typically reported in "specific
|
Solution: which of these is not a mineral characteristic?
| 5
|
NIv2
|
task470_mrqa_question_generation
|
fs_opt
|
TASK DEFINITION: Given a context passage, generate a question from the passage such that its answer is shortest continous span from the passage.
PROBLEM: Almost nothing is left of the Bastille except some remains of its stone foundation that were relocated to the side of the Boulevard Henri IV. Historians were critical of the Bastille in the early 19th century, and believe the fortress to have been a relatively well-administered institution, but deeply implicated in the system of French policing and political control during the 18th century.
SOLUTION: What material was used for Bastille?
PROBLEM: Adam Park is a fictional major character from the universe of the American television series franchise Power Rangers, played by Johnny Yong Bosch.
SOLUTION: To which fictional work does Adam Park belong in?
PROBLEM: Minerals are everywhere! Scientists have identified more than 4,000 minerals in Earths crust, although the bulk of the planet is composed of just a few. A mineral possesses the following qualities: It must be solid. It must be crystalline, meaning it has a repeating arrangement of atoms. It must be naturally occurring. It must be inorganic. It must have a specific chemical composition. Minerals can be identified by their physical properties, such as hardness, color, luster (shininess), and odor. The most common laboratory technique used to identify a mineral is X-ray diffraction (XRD), a technique that involves shining an X-ray light on a sample, and observing how the light exiting the sample is bent. XRD is not useful in the field, however. The definition of a mineral is more restricted than you might think at first. For example, glass is made of sand, which is rich in the mineral quartz. But glass is not a mineral, because it is not crystalline. Instead, glass has a random assemblage of molecules. What about steel? Steel is made by mixing different metal minerals like iron, cobalt, chromium, vanadium, and molybdenum, but steel is not a mineral because it is made by humans and therefore is not naturally occurring. However, almost any rock you pick up is composed of minerals. Below we explore the qualities of minerals in more detail. Minerals are "crystalline" solids. A crystal is a solid in which the atoms are arranged in a regular, repeating pattern. Notice that in Figure 1.1 the green and purple spheres, representing sodium and chlorine, form a repeating pattern. In this case, they alternate in all directions. Sodium ions (purple balls) bond with chlo- ride ions (green balls) to make table salt (halite). All of the grains of salt that are in a salt shaker have this crystalline structure. Organic substances are the carbon-based compounds made by living creatures and include proteins, carbohydrates, and oils. Inorganic substances have a structure that is not characteristic of living bodies. Coal is made of plant and animal remains. Is it a mineral? Coal is a classified as a sedimentary rock, but is not a mineral. Minerals are made by natural processes, those that occur in or on Earth. A diamond created deep in Earths crust is a mineral, but a diamond made in a laboratory by humans is not. Be careful about buying a laboratory-made diamond for jewelry. It may look pretty, but its not a diamond and is not technically a mineral. Nearly all (98.5%) of Earths crust is made up of only eight elements - oxygen, silicon, aluminum, iron, calcium, sodium, potassium, and magnesium - and these are the elements that make up most minerals. All minerals have a specific chemical composition. The mineral silver is made up of only silver atoms and diamond is made only of carbon atoms, but most minerals are made up of chemical compounds. Each mineral has its own chemical formula. Table salt (also known as halite), pictured in Figure 1.1, is NaCl (sodium chloride). Quartz is always made of two oxygen atoms (red) bonded to a silicon atom (grey), represented by the chemical formula SiO2 (Figure 1.2). Quartz is made of two oxygen atoms (red) bonded to a silicon atom (grey). In nature, things are rarely as simple as in the lab, and so it should not come as a surprise that some minerals have a range of chemical compositions. One important example in Earth science is olivine, which always has silicon and oxygen as well as some iron and magnesium, (Mg, Fe)2 SiO4 . Some minerals can be identified with little more than the naked eye. We do this by examining the physical properties of the mineral in question, which include: Color: the color of the mineral. Streak: the color of the minerals powder (this is often different from the color of the whole mineral). Luster: shininess. Density: mass per volume, typically reported in "specific
SOLUTION:
|
which of these is not a mineral characteristic?
| 8
|
NIv2
|
task470_mrqa_question_generation
|
fs_opt
|
TASK DEFINITION: Given a context passage, generate a question from the passage such that its answer is shortest continous span from the passage.
PROBLEM: So that people in developed nations maintain a good lifestyle and people in developing nations have the ability to improve their lifestyles, natural resources must be conserved and protected (Figure 1.1). People are researching ways to find renewable alternatives to non-renewable resources. Here is a checklist of ways to conserve resources: Buy less stuff (use items as long as you can, and ask yourself if you really need something new). Reduce excess packaging (drink tap water instead of water from plastic bottles). Recycle materials such as metal cans, old cell phones, and plastic bottles. Purchase products made from recycled materials. Reduce pollution so that resources are maintained. Prevent soil erosion. Plant new trees to replace those that are cut down. Drive cars less, take public transportation, bicycle, or walk. Conserve energy at home (turn out lights when they are not needed). Click image to the left or use the URL below. URL: Click image to the left or use the URL below. URL:
SOLUTION: which one of these can you not recycle
PROBLEM: A novel Ca2+/calmodulin-dependent protein kinase II (CaM Kinase II) inhibitor, KN-93 potently inhibits gastric acid secretion from parietal cells. As previously reported (1), treatment of parietal cells with a selective inhibitor of CaM kinase II, KN-62 resulted in the inhibition of cholinergic-stimulated rabbit parietal cell secretion, whereas it failed to inhibit the histamine and forskolin response. In contrast effects of carbachol, histamine and forskolin were significantly inhibited by KN-93 with an IC50 of 0.15, 0.3 and 1 microM, respectively; these effects occurred without any changes in intracellular cyclic AMP and Ca2+ levels. In the present study we investigated the mechanism by which KN-93 acts upon the acid-secreting machinery of gastric parietal cells. Neither redistribution of the proton pump activity nor the morphological transformation were affected by KN-93. The drug only weakly inhibited the H+, K(+)-ATPase activity but strongly dissipated the proton gradient formed in the gastric membrane vesicles and reduced the volume of luminal space. Thus KN-93 acts at pH gradient formation whereas KN-62 acts only at CaM Kinase II.
SOLUTION: Which kinase is inhibited by the small molecule KN-93?
PROBLEM: Nevow (pronounced like the French nouveau) is a Python web application framework originally developed by the company Divmod.
SOLUTION:
|
What programming language was used to write Nevow?
| 8
|
NIv2
|
task470_mrqa_question_generation
|
fs_opt
|
Given a context passage, generate a question from the passage such that its answer is shortest continous span from the passage.
Input: Consider Input: The movie opens with James Reece (Jonathan Rhys Meyers) driving through the streets of Paris in a black SUV to work. Reece works in the American Embassy as an aide to Ambassador Bennington (Richard Durden), the U.S. Ambassador to France. Taking a delivery of some forms from the Ambassador's secretary, he goes over Bennington's itinerary for the next few days, centering around a major summit in which the U.S., France, and several other nations are preparing foreign aid to the African continent. Bennington shows that he is more absorbed right now in a chess game he's playing with Reece during all this time. Despite paying less attention to the board and the game than Bennington is, Reece quickly checkmates him to win.Reece receives a call from an unknown source (voiced by David Gasman) directing him to a silver BMW in the parking lot, excusing himself with a cover story to Bennington that he has to review the Summit's planned seating arrangement. Going to the parking lot, Reece opens a code-locked security compartment in the trunk of his SUV to reveal a firearm and several French license plates. He removes the license plate from the silver BMW and replaces it with one of the plates he has stowed away in his SUV. He then moves his SUV to another parking space and waits there, watching the silver BMW. He watches several men get into the vehicle, put a briefcase into its trunk, and drive away.Arriving home, Reece gets another call from the same source. Reece is in fact a CIA operative working in the Embassy as a cover. He does minor jobs for his superiors, and is eager to move up into Special Ops. His superior assures him he'll get his chance, but for right now he is needed to secure a hidden transmission chip in the French Foreign Minister's office during a meeting with Ambassador Bennington. Reece doesn't believe he was given a chip, but is told it's in his left jacket pocket. Checking his jacket, he finds the chip there.Sitting in his apartment, Reece examines the chip. He is interrupted by a knock on his door. It's his girlfriend, Caroline (Kasia Smutnak) (pronounced Cah-roll-een, the 'ine' being pronounced like in the word 'magazine'). Caroline kisses Reece and tells him she has a surprise. She sits him in a chair and makes him keep his back to her. He can hear her undressing and changing into a different outfit. When she tells him to look, his jaw drops at the sight of her wearing a sexy strapless dress. He thinks he recognizes the fabric, and Caroline tells him she made it out of their bedroom curtains-- Caroline is a clothing designer. The two of them quickly start to undress as they head into the bedroom to make out.Reece arrives the next day at the conference site to give Bennington a summary of what is intended to be discussed at the meeting. Bennington invites Reece to attend the meeting with him.During the meeting, Reece discreetly takes the chip (disguising it by putting a piece of gum in his mouth and offering another piece to the Minister's secretary) and tries to put it under the lampstand beside his seat, using his chewing gum as an adhesive. However, the gum fails to hold and twice it falls back to the floor in plain sight. Frustrated, and barely managing to keep the chip hidden, as a diversion Reece finally questions the Foreign Minister (Eric Godon) about his having several Goyas in his office. The Minister says he does, and offers to show them to Bennington, who is very interested in Goya art. As Bennington accompanies the Minister and secretary to see the Goyas, leaving Reece alone in the meeting room, Reece takes the stapler from the Minister's desk and staples the chip to the underside of the desk... but accidentally leaves the stapler open as he exits.Arriving home that evening, Reece is disquieted as the lights in the hallway go out. He finds what looks like a trail of blood leading to a door out onto the roof of the building. Grabbing a broom left in
Output: What are the terrorists targeting?
Input: Consider Input: Jan Muhlstein (born 3 July 1949 in Most, Czechoslovakia) is a journalist, German Jewish activist and the former chair of the Union of Progressive Jews in Germany.
Output: Which language or languages is Jan Mühlstein fluent in?
Input: Consider Input: Astro Awani is the in-house rolling television news and current affairs channel providing 24-hour news coverage including news in Malay.
|
Output: Which industry is Astro Awani associated with?
| 2
|
NIv2
|
task470_mrqa_question_generation
|
fs_opt
|
You will be given a definition of a task first, then an example. Follow the example to solve a new instance of the task.
Given a context passage, generate a question from the passage such that its answer is shortest continous span from the passage.
In 1582 the united provinces invited francis, duke of anjou to lead them; but after a failed attempt to take antwerp in 1583, the duke left the netherlands again. after the assassination of william of orange (10 july 1584), both henry iii of france and elizabeth i of england declined the offer of sovereignty. however, the latter agreed to turn the united provinces into a protectorate of england (treaty of nonsuch, 1585), and sent the earl of leicester as governor-general. this was unsuccessful and in 1588 the provinces became a confederacy. the union of utrecht is regarded as the foundation of the republic of the seven united provinces, which was not recognized by the spanish empire until the peace of westphalia in 1648.
Solution: In what year did francis, duke of anjou leave the netherlands?
Why? The generated question is perfect. Because the question is based on second sentence of the input passage and its answer is 1583.
New input: Esra Erol (6 November 1985) is a Turkish female footballer currently playing in the Turkish First League in defender position for Kirecburnu Spor in Istanbul.
Solution:
|
Player Esra Erol plays for what team?
| 0
|
NIv2
|
task470_mrqa_question_generation
|
fs_opt
|
Given a context passage, generate a question from the passage such that its answer is shortest continous span from the passage.
One example: In 1582 the united provinces invited francis, duke of anjou to lead them; but after a failed attempt to take antwerp in 1583, the duke left the netherlands again. after the assassination of william of orange (10 july 1584), both henry iii of france and elizabeth i of england declined the offer of sovereignty. however, the latter agreed to turn the united provinces into a protectorate of england (treaty of nonsuch, 1585), and sent the earl of leicester as governor-general. this was unsuccessful and in 1588 the provinces became a confederacy. the union of utrecht is regarded as the foundation of the republic of the seven united provinces, which was not recognized by the spanish empire until the peace of westphalia in 1648.
Solution is here: In what year did francis, duke of anjou leave the netherlands?
Explanation: The generated question is perfect. Because the question is based on second sentence of the input passage and its answer is 1583.
Now, solve this: The London Marathon celebrates its 32nd birthday. That is 32 years of stresses and anxieties, blisters and painful knees, and tales that are hard to believe. Somehow, I've managed to run four of _ . And I have medals to prove it. It seemed like a good idea at the time. I watched the first London Marathon on March 29th, 1981. It seemed extraordinary that normal people would want to run 26 miles and 385 yards. And, it must be said that they looked strange and not quite steady at the end of it all. There are, indeed, terrible tales of people losing consciousness when they reach the finishing line. But it drew all my attention. I knew I had to do it. Three years later I was living in London, not far from Greenwich where the event begins, and it seemed the perfect opportunity to give it a go. I was only a short train ride from the starting line, but more than 26 miles from the finish. "Who cares?" I thought. By the end I did. The moment I crossed that finishing line and had that medal placed around my neck was one of the finest in my life. The sense of achievement was great. Knowing that I'd run a Marathon felt extremely good. London provides one of the easiest of all the officially approved marathons because most of its course is flat. Yes, there are the cobblestones while running through the Tower of London, and there are the quiet patches where crowds are thin and you are crying out for some encouragement -- those things matter to the "fun" runners like myself, but the serious runners don't think of such things. Since 1981,almost half a million people have completed the London Marathon, raising more than $ 125 million for charity. For the majority of the runners, this is what it is all about. It is for charity, for fun, for self-development. I have always loved it. It's crazy, and it's one of the greatest things I've ever done. If you want to feel as though you've achieved something, run a marathon.
Solution:
|
From what place does the London Marathon start?
| 6
|
NIv2
|
task470_mrqa_question_generation
|
fs_opt
|
Given the task definition, example input & output, solve the new input case.
Given a context passage, generate a question from the passage such that its answer is shortest continous span from the passage.
Example: In 1582 the united provinces invited francis, duke of anjou to lead them; but after a failed attempt to take antwerp in 1583, the duke left the netherlands again. after the assassination of william of orange (10 july 1584), both henry iii of france and elizabeth i of england declined the offer of sovereignty. however, the latter agreed to turn the united provinces into a protectorate of england (treaty of nonsuch, 1585), and sent the earl of leicester as governor-general. this was unsuccessful and in 1588 the provinces became a confederacy. the union of utrecht is regarded as the foundation of the republic of the seven united provinces, which was not recognized by the spanish empire until the peace of westphalia in 1648.
Output: In what year did francis, duke of anjou leave the netherlands?
The generated question is perfect. Because the question is based on second sentence of the input passage and its answer is 1583.
New input case for you: The Ehlers-Danlos syndrome is a heritable connective-tissue disorder caused by defects in fibrillar-collagen metabolism. Mutations in the type V collagen genes account for up to 50 percent of cases of classic Ehlers-Danlos syndrome, but many other cases are unexplained. We investigated whether the deficiency of the tenascins, extracellular-matrix proteins that are highly expressed in connective tissues, was associated with the Ehlers-Danlos syndrome. We screened serum samples from 151 patients with the classic, hypermobility, or vascular types of the Ehlers-Danlos syndrome; 75 patients with psoriasis; 93 patients with rheumatoid arthritis; and 21 healthy persons for the presence of tenascin-X and tenascin-C by enzyme-linked immunosorbent assay. We examined the expression of tenascins and type V collagen in skin by immunohistochemical methods and sequenced the tenascin-X gene. Tenascin-X was present in serum from all normal subjects, all patients with psoriasis, all patients with rheumatoid arthritis, and 146 of 151 patients with the Ehlers-Danlos syndrome. Tenascin-X was absent from the serum of the 5 remaining patients with Ehlers-Danlos syndrome, who were unrelated. Tenascin-X deficiency was confirmed in these patients by analysis of skin fibroblasts and by immunostaining of skin. The expression of tenascin-C and type V collagen was normal in these patients. All five of these patients had hypermobile joints, hyperelastic skin, and easy bruising, without atrophic scarring. Tenascin-X mutations were identified in all tenascin-X-deficient patients; one patient had a homozygous tenascin-X gene deletion, one was heterozygous for the deletion, and three others had homozygous truncating point mutations, confirming a causative role for tenascin-X and a recessive pattern of inheritance. Tenascin-X deficiency causes a clinically distinct, recessive form of the Ehlers-Danlos syndrome. This finding indicates that factors other than the collagens or collagen-processing enzymes can cause the syndrome and suggests a central role for tenascin-X in maintaining the integrity of collagenous matrix.
Output:
|
What tissue is most affected in Ehlers-Danlos syndromes?
| 1
|
NIv2
|
task470_mrqa_question_generation
|
fs_opt
|
Part 1. Definition
Given a context passage, generate a question from the passage such that its answer is shortest continous span from the passage.
Part 2. Example
In 1582 the united provinces invited francis, duke of anjou to lead them; but after a failed attempt to take antwerp in 1583, the duke left the netherlands again. after the assassination of william of orange (10 july 1584), both henry iii of france and elizabeth i of england declined the offer of sovereignty. however, the latter agreed to turn the united provinces into a protectorate of england (treaty of nonsuch, 1585), and sent the earl of leicester as governor-general. this was unsuccessful and in 1588 the provinces became a confederacy. the union of utrecht is regarded as the foundation of the republic of the seven united provinces, which was not recognized by the spanish empire until the peace of westphalia in 1648.
Answer: In what year did francis, duke of anjou leave the netherlands?
Explanation: The generated question is perfect. Because the question is based on second sentence of the input passage and its answer is 1583.
Part 3. Exercise
An electric transformer is a device that uses electromagnetic induction to change the voltage of electric current. Electromagnetic induction is the process of generating current with a magnetic field. It occurs when a magnetic field and electric conductor, such as a coil of wire, move relative to one another. A transformer may either increase or decrease voltage. You can see the basic components of an electric transformer in the Figure 1.1. Click image to the left or use the URL below. URL: The transformer in the diagram consists of two wire coils wrapped around an iron core. Each coil is part of a different circuit. When alternating current passes through coil P, it magnetizes the iron core. Because the current is alternating, the magnetic field of the iron core keeps reversing. This is where electromagnetic induction comes in. The changing magnetic field induces alternating current in coil S of the other circuit. Notice that coil P and coil S in the Figure 1.1 have the same number of turns of wire. In this case, the voltages of the primary and secondary currents are the same. Usually, the two coils of a transformer have different numbers of turns. In that case, the voltages of the two currents are different. When coil S has more turns than coil P, the voltage in the secondary current is greater than the voltage in the primary current (see Figure 1.2). This type of transformer is called a step-up transformer. Thats because it steps up, or increases, the voltage. When coil S has fewer turns of wire than coil P, the voltage in the secondary current is less than the voltage in the primary current (see Figure 1.3). This type of transformer is called a step-down transformer because it steps down, or decreases, the voltage. Q: Both step-up and step-down transformers are used in the electrical grid that carries electricity from a power plant to your home. Where in the grid do you think step-down transformers might be used? A: One place that step-down transformers are used is on the electric poles that supply current to homes. They reduce the voltage of the electric current before it enters home circuits.
Answer:
|
an electric transformer contains
| 7
|
NIv2
|
task470_mrqa_question_generation
|
fs_opt
|
Given a context passage, generate a question from the passage such that its answer is shortest continous span from the passage.
Example Input: C.D. "Charlie" Bales, the fire chief of the small American ski town of Nelson, Washington, is intelligent, humorous, charismatic, athletic and skilled. Bales is sensitive about his large nose, which many in town have learned to not mention. He is unable to have it surgically altered because of a dangerous allergy to anesthetics. He is close to many in town, especially his godsister, Dixie, who owns the town diner and several rental homes. He becomes immediately attracted to beautiful newcomer Roxanne Kowalski, an astronomy student renting from Dixie while searching for a new comet. She adores Bales, but only as a friend, preferring Chris, a handsome but dim fireman. Roxanne goes to Bales for help when Chris fails to advance their relationship further than curious glances. Through a turn of events, she falsely believes Chris is deeply intelligent. When Bales informs Chris of Roxanne's interest, Chris gets sick, intimidated by intelligent women. Chris starts to write her a letter, but takes all day with little result. He convinces Bales to write the letter, with prose that soon bowls over Roxanne. When informed that Roxanne wants to meet him, Chris again gets sick and refuses to meet until Bales comes up with a plan to allow him to be as brilliant as his letter makes him appear. Chris arrives at Roxanne's house with a hunter's cap on, hiding the earphones that relay Bales' words. When the equipment fails, Chris bungles the meeting by speaking his own crass thoughts. After Roxanne storms back into the house furious, Chris begs Bales to fix his mess again. At first he repeats what he is told from under a tree beneath Roxanne's window, but soon also ruins that. Then they switch jackets and hats so Bales can speak the words as Chris. They achieve their goal, and she invites Chris in to make love. Roxanne gets word about the comet and has to go out of town for a week. Since she can't find Chris, she gives Bales the address of her hotel and asks him to tell Chris to write to her. Bales writes her several times a day, each letter more incredible than the last. They affect Roxanne so deeply that she returns early. Bales is writing a new letter to her in Dixie's diner when he finds out that Chris (who knows nothing about the letters) is on his way to see Roxanne. He arrives at her home and warns Chris that Roxanne would be mentioning some letters that he supposedly wrote. She tries to get Chris to be the man in the letters, revealing that his looks are only secondary to her. Knowing that his looks are all he has, Chris runs out, leaving her confused. Dixie puts the last letter under her door and after reading it, Roxanne calls Bales over. Chris prepares to leave town with a bartender, Sandy, whom he met while Roxanne was away. When she asks if he has told Roxanne (the women are acquaintances), he replies that he will write her a letter since he has a history of it. Bales arrives, unaware that Roxanne knows the truth. She asks him to read one of the letters and then to look at the back, which shows that Dixie revealed its true author. She explodes in anger that he lied to her. He retorts that he simply wanted to tell her how he felt about her, but she was only interested in Chris's face and body. When he reminds her that it only took a few nice words for Chris to get her into bed, she punches him in the face and throws him out. As he prepares to say more he stops and sniffs the air. He slowly walks back to the firehouse and alerts his team, who then "follow his nose" until they find and extinguish the fire. During their celebration afterwards, someone mentions his nose and although everyone thinks he will get upset, he doesn't. Back home, sitting on his roof, Bales hears someone speaking his words to him. It's Roxanne, declaring that she realizes that it was everything from Bales that she loved, not Chris'
Example Output: Who is C.D.'s god-sister?
Example Input: Precursor cells have been shown to be affected by oxidative stress, in vivo and vitro, but little is known about the expression of antioxidant mechanisms in neuronal/glial differentiation. We have characterized the expression of Cu/Zn superoxide dismutase (Cu/Zn SOD), one of the main antioxidant proteins involved in the breakdown of superoxide, in the immature rat dorsolateral subventricular zone (SVZ), rostral migratory stream (RMS) and hippocampal subgranular zone (SGZ). Progenitor cells were identified immunohistochemically on cryostat sections by 5'Bromodeoxyuridine (BrdU) incorporation and expressing cells were further characterized using double labeling for progenitor markers. In the SVZ, only a subpopulation of BrdU+ cells, mostly found in the medial SVZ, expressed Cu/Zn SOD. These cells were mostly nestin+ and some were also vimentin+. In contrast, in the lateral SVZ few Cu/Zn SOD+/BrdU+ cells were found. These were primarily nestin+, vimentin-, showed some PSA-NCAM expression, but only a few were NG2+. In the RMS and SGZ virtually all BrdU+ progenitors were Cu/Zn SOD+ and expressed nestin and vimentin. Some RMS cells were also PSA-NCAM+. These findings show a heterogeneous expression of Cu/Zn SOD in restricted cell types in the germinative zones and suggest a role for antioxidant Cu/Zn SOD in progenitor cells of the immature rat brain.
Example Output: Which intermediate filament (IF) protein can be used as a non-specific marker of the neuronal precursor cells of the subventricular zone?
Example Input: The first step in the management of restless legs syndrome (RLS) is to identify, and if possible to treat any condition which might cause or worsen RLS, such as iron deficiency or some drug treatments. The patients suffering from RLS should be prompted to keep a healthy sleep schedule. Drug treatment should be restricted to patients with a clear clinical diagnosis, decided on an individual basis, when the clinical impact is serious. Four drug classes are central to the treatment of RLS: dopaminergic agents, some antiepileptics, opioids, and benzodiazepines. Dopaminergic agonists are the treatment of choice, especially when daily treatment is indicated, or if the symptoms are severe. Two dopaminergic agonists are licensed in France for the treatment of RLS: ropinirole (Adartrel) and pramipexole (Sifrol). After initiation of treatment, the patients should benefit from a regular follow-up in order to evaluate the efficacy of treatment and to identify possible side-effects. Special care should be given to the detection of augmentation, a phenomenon characterized by a paradoxical worsening of the symptoms with treatment. Some particular conditions, such as RLS comorbid with renal insufficiency, during pregnancy, and in the child are discussed.
Example Output:
|
Which deficiency is the cause of restless leg syndrome?
| 3
|
NIv2
|
task470_mrqa_question_generation
|
fs_opt
|
Given a context passage, generate a question from the passage such that its answer is shortest continous span from the passage.
[EX Q]: A house of cards? Sounds unbelievable, doesn't it? Not if the architect is 31-year-old Bryan Berg. He's made a career out of building fantastic card houses, stadiums, capitols, castles -- and the world's tallest card tower. How does he do it? Bryan's structures are amazing because they are made entirely of perfectly balanced, freestanding playing cards. He never uses glue, tape, or anything else to hold the cards together. Nor does he fold the cards. He's discovered another way to make a strong house of cards, using a trick from nature. To make plants strong, nature builds them with cells that have tough walls. Rows and rows of these cells form a grid that helps leaves and stems keep their shape. Bees use the same kind of repeating pattern to create strong honeycombs, where they live and store honey. Bryan designs similar grids, using cards to create a repeating pattern of cells. He begins with a single cell made by balancing four cards against one another to form a box. Then he repeats the cell over and over, expanding outward to form the grid, which makes a good foundation for a strong card structure. The larger the grid, the more weight it can carry. Sometimes Bryan uses several cards, instead of just one, to construct the cell walls, making the grid even stronger. The trick, he tells kids when he speaks in classrooms, is to place your cards as tightly together as possible when laying out your grid, making sure the cards are not leaning at all. After building this solid base, Bryan lays cards across the top to make the floor for the next "story" of the building. He may add towers, columns, steeples, or domes. Using the principle of repeating cells, Bryan builds structures of amazing strength. In the Cards Not surprisingly, Bryan has always been interested in building things. Growing up on a "big, old farm" in rural Iowa, he had plenty of room to play. "We were in the middle of nowhere," Bryan remembers, "with lots of space to do whatever we wanted. I was always making something, using things like sticks or bales of hay." Bryan's grandfather taught him how to stack cards. Bryan's two interests -- building and card stacking -- soon combined. But stacking in his family's farmhouse was challenging. "Our old house had wood floors that weren't all level," he reports. "And they weren't very firm. When people walked around, it was like 'earthquake action.' It was a challenge to build something that wouldn't fall down immediately." Bryan constructed tower after tower; he went through a lot of trial and error before he built anything taller than himself. When he placed a few decks of cards on top of his grid, he discovered how strong it was. Bryan's towers began to grow taller. How Tall Is Too Tall? Bryan's first Guinness World Record for the world's tallest card tower came in the spring of 1992, when he was in high school. Learning that the world record was 12 feet 10 inches, Bryan built a slim tower that topped out at 14 feet 6 inches. Done as a project for his geometry class, it took him 40 hours and 208 decks of cards. Since then he's gone on to win world records for even taller buildings. His latest winner measured 25 feet 3.5 inches and used about 2,400 decks of cards. _ Why don't these towers fall down? The key is in a good solid base, a repeating pattern of stories, and a tapering top. Bryan likes to point out how card buildings resemble real ones. They are built cell by cell, story by story. The separate parts make one strong whole. The heavier the building, the stronger and more stable it is. But the weight can't all be at the top. After spending so much time building something so cool, Bryan admits it's sometimes painful to see his structures destroyed. But he compares his work to the building of a sandcastle or an ice sculpture.
[EX A]: What was Bryan's first world record?
[EX Q]: On at least one occasion they succeeded and formed the Kingdom of Kurdistan, which lasted from September 1922 until July 1924.
[EX A]: Which year did Kingdom of Kurdistan end?
[EX Q]: Spotlight at Salem Academy and College Academic Camp: Creative Writing, Environmental Education/ Science, Language Camp Address 500 Salem Avenue Winston-Salem, North Carolina 27101 USA (800) 833-1753 Salem spotlight is designed to arouse intellectual curiosity with emphasis on the experience and development of the individual... (more) Get more information about Spotlight at Salem Academy and College Caribbean Summer Sea Camp Academic Camp: Environmental Education/ Science Camp Address Off-Season Address Box 37 North Coast Road PO Box 1461 Little Cayman, BWI Princeton, New Jersey Cayman Islands 08542 USA (609) 933-4559 The Caribbean Summer Sea Camp is a one-week adventure on Little Cayman Island. Campers dive or snorkel to explore the wonders of coral reefs, and view the diverse life in the sea around the island. Coastal Camp at Headlands Institute Academic Camp: Environmental Education/ Science Camp Address Bldg. 1033 Golden Gate National Recreation Area Sausalito, California 94965 USA (415) 332-6961 The Coastal Camp at Headlands Institute combines marine and coastal ecology themes with hands-on educational games and exciting opportunities for discovery in the great outdoors. By promoting environmental work, Coastal Camp allows kids to become responsible earth citizens. Swift Nature Camp Academic Camp: Environmental Education/ Science Camp Address Off-Season Address W7471 Ernie Swift Rd 25 Baybrook Minong, Wisconsin 54859 Oak Brook, Illinois USA 60523 (715) 466-5666 (630) 654-8036 Located in the Northwoods of Wisconsin on a 1,500-acre lake, this small camp offers hands-on nature studies. Self accomplishment is promoted while competition takes a back seat: Horses, Swimming, Scuba, Skiing, Sailing, Canoeing, Arts & Crafts and much more.
[EX A]:
|
Alice, a girl of 10, hopes to learn more about ecology by playing games. Which telephone number should she dial?
| 6
|
NIv2
|
task470_mrqa_question_generation
|
fs_opt
|
You will be given a definition of a task first, then an example. Follow the example to solve a new instance of the task.
Given a context passage, generate a question from the passage such that its answer is shortest continous span from the passage.
In 1582 the united provinces invited francis, duke of anjou to lead them; but after a failed attempt to take antwerp in 1583, the duke left the netherlands again. after the assassination of william of orange (10 july 1584), both henry iii of france and elizabeth i of england declined the offer of sovereignty. however, the latter agreed to turn the united provinces into a protectorate of england (treaty of nonsuch, 1585), and sent the earl of leicester as governor-general. this was unsuccessful and in 1588 the provinces became a confederacy. the union of utrecht is regarded as the foundation of the republic of the seven united provinces, which was not recognized by the spanish empire until the peace of westphalia in 1648.
Solution: In what year did francis, duke of anjou leave the netherlands?
Why? The generated question is perfect. Because the question is based on second sentence of the input passage and its answer is 1583.
New input: The first step in the management of restless legs syndrome (RLS) is to identify, and if possible to treat any condition which might cause or worsen RLS, such as iron deficiency or some drug treatments. The patients suffering from RLS should be prompted to keep a healthy sleep schedule. Drug treatment should be restricted to patients with a clear clinical diagnosis, decided on an individual basis, when the clinical impact is serious. Four drug classes are central to the treatment of RLS: dopaminergic agents, some antiepileptics, opioids, and benzodiazepines. Dopaminergic agonists are the treatment of choice, especially when daily treatment is indicated, or if the symptoms are severe. Two dopaminergic agonists are licensed in France for the treatment of RLS: ropinirole (Adartrel) and pramipexole (Sifrol). After initiation of treatment, the patients should benefit from a regular follow-up in order to evaluate the efficacy of treatment and to identify possible side-effects. Special care should be given to the detection of augmentation, a phenomenon characterized by a paradoxical worsening of the symptoms with treatment. Some particular conditions, such as RLS comorbid with renal insufficiency, during pregnancy, and in the child are discussed.
Solution:
|
Which deficiency is the cause of restless leg syndrome?
| 0
|
NIv2
|
task470_mrqa_question_generation
|
fs_opt
|
Given a context passage, generate a question from the passage such that its answer is shortest continous span from the passage.
Example input: In 1582 the united provinces invited francis, duke of anjou to lead them; but after a failed attempt to take antwerp in 1583, the duke left the netherlands again. after the assassination of william of orange (10 july 1584), both henry iii of france and elizabeth i of england declined the offer of sovereignty. however, the latter agreed to turn the united provinces into a protectorate of england (treaty of nonsuch, 1585), and sent the earl of leicester as governor-general. this was unsuccessful and in 1588 the provinces became a confederacy. the union of utrecht is regarded as the foundation of the republic of the seven united provinces, which was not recognized by the spanish empire until the peace of westphalia in 1648.
Example output: In what year did francis, duke of anjou leave the netherlands?
Example explanation: The generated question is perfect. Because the question is based on second sentence of the input passage and its answer is 1583.
Q: Leonard (Phoenix) is walking along a bridge over a creek in Brooklyn, when suddenly he jumps into the water in an attempted suicide. He changes his mind and quickly walks home to his parents' apartment. His mother, seeing him dripping wet, tells her husband their son has tried it again and it becomes evident that Leonard has tried to kill himself before. His parents tell him that a potential business partner and his family are invited for dinner that night and ask him to be present. When they arrive, Leonard finds that he had been set up with the other family's daughter, Sandra (Shaw). She inquires about his interest in photography and notices a photo of a girl above his headboard. He explains he had been engaged to the girl for several years, but the relationship was broken off when it turned out both he and his fiancee carried the gene for TaySachs disease, which results in diseased children who generally don't live beyond age 12, so they would be unable to have healthy children. Leonard meets a new neighbor, Michelle (Paltrow), and is immediately attracted to her, choosing to ignore that she has a drug usage problem. He learns that she is dating a married partner in her law firm, Ronald (Koteas). At her request, Leonard agrees to meet Ronald and Michelle for dinner at a restaurant. The couple leave him later that evening, as they have plans to attend the Metropolitan Opera. Leonard returns home upset, but to his surprise, Sandra arrives, sent over by Leonard's parents. She is under the impression that Leonard wanted her to come by, but realizes by his surprised look, that she was set up. She apologizes for the misunderstanding and says that if he isn't interested, a lot of other guys are. Leonard says that he likes her, and they kiss and eventually make love, and with time, his relationship with Sandra deepens. Michelle calls Leonard and says she is sick. He takes her to the hospital, where she has a D&C for a miscarriage. She had not known she was pregnant and is even more upset that Ronald didn't respond to her calls. Leonard takes her home but Ronald arrives. Leonard hides while Ronald apologizes to Michelle for not having come to her aid. Michelle coldly asks Ronald to leave. She then asks Leonard to write something on her forearm with his finger while she falls asleep. Leonard writes "I love you". Two weeks later, Michelle meets Leonard on the roof of their building and tells him that she has broken up with Ronald and is going to San Francisco. Leonard tells her not to leave and professes his love for her. They have sex and plan to leave together the next day for San Francisco. On New Year's Eve, Leonard buys an engagement ring for Michelle. He is then summoned by Sandra's father and is offered a partnership in the family businesses, with the assumption that he is going to marry Sandra. Noticing the jeweler's gift bag Leonard is holding, the father assumes it is for Sandra; Leonard lies that it is. During his parents' New Year's Eve party, Leonard ducks out to the courtyard to meet Michelle. Michelle arrives ten minutes past departure time and tells Leonard that she isn't going to San Francisco, because Ronald, having learned Michelle is leaving him for California, decided to leave his wife and children for her. Distraught, Leonard breaks things off with her for good. Feeling desolate, Leonard heads to the beach, presumably intending to kill himself. When he drops a glove that Sandra had bought for him, he realizes that, in Sandra, he has found someone who loves him and with whom he can build a decent life. He picks up the glove and sees the boxed engagement ring lying on the sand, where he had thrown it from the boardwalk earlier. He returns to the party, where he gives Sandra the ring and embraces her in a prolonged hug.
A:
|
Who did Leonard's parents try to set him up with?
| 3
|
NIv2
|
task470_mrqa_question_generation
|
fs_opt
|
Given the task definition, example input & output, solve the new input case.
Given a context passage, generate a question from the passage such that its answer is shortest continous span from the passage.
Example: In 1582 the united provinces invited francis, duke of anjou to lead them; but after a failed attempt to take antwerp in 1583, the duke left the netherlands again. after the assassination of william of orange (10 july 1584), both henry iii of france and elizabeth i of england declined the offer of sovereignty. however, the latter agreed to turn the united provinces into a protectorate of england (treaty of nonsuch, 1585), and sent the earl of leicester as governor-general. this was unsuccessful and in 1588 the provinces became a confederacy. the union of utrecht is regarded as the foundation of the republic of the seven united provinces, which was not recognized by the spanish empire until the peace of westphalia in 1648.
Output: In what year did francis, duke of anjou leave the netherlands?
The generated question is perfect. Because the question is based on second sentence of the input passage and its answer is 1583.
New input case for you: We need natural resources for just about everything we do. We need them for food and clothing, for building materials and energy. We even need them to have fun. Table 20.1 gives examples of how we use natural resources. Can you think of other ways we use natural resources? Use Vehicles Resources Rubber for tires from rubber trees Steel frames and other metal parts from minerals such as iron Example iron ore Use Electronics Resources Plastic cases from petroleum prod- ucts Glass screens from minerals such as lead Example lead ore Homes Nails from minerals such as iron Timber from trees spruce timber Jewelry Gemstones such as diamonds Minerals such as silver silver ore Food Sunlight, water, and soil Minerals such as phosphorus corn seeds in soil Clothing Wool from sheep Cotton from cotton plants cotton plants Recreation Water for boating and swimming Forests for hiking and camping pine forest Some natural resources are renewable. Others are not. It depends in part on how we use them. Renewable resources can be renewed as they are used. An example is timber, which comes from trees. New trees can be planted to replace those that are cut down. Sunlight is a renewable resource. It seems we will never run out of that! Just because a resource is renewable, it doesnt mean we should use it carelessly. If we arent careful, we can pollute resources. Then they may no longer be fit for use. Water is one example. If we pollute a water source it may not be usable for drinking, bathing or any other type of use. We can also overuse resources that should be renewable. In this case the resources may not be able to recover. For example, fish are renewable resources. Thats because they can reproduce and make more fish. But water pollution and overfishing can cause them to die out if their population becomes too low. Figure 20.1 shows another example. Some resources cant be renewed. At least, they cant be renewed fast enough to keep up with use. Fossil fuels are examples. It takes millions of years for them to form. We are using them up much more quickly. Elements that are used to produce nuclear power are other examples. They include uranium. This element is already rare. Sooner or later, it will run out. Supplies of non-renewable resources are shrinking. This makes them harder to get. Oil is a good example. Oil reserves beneath land are running out. So oil companies have started to drill for oil far out in the ocean. This costs more money. Its also more dangerous. Figure 20.2 shows an oil rig that exploded in 2010. The explosion killed 11 people. Millions of barrels of oil spilled into the water. It took months to plug the leak. Rich nations use more natural resources than poor nations. In fact, the richest 20 percent of people use 85 percent of the worlds resources. What about the poorest 20 percent of people? They use only 1 percent of the worlds resources. You can see this unequal distribution of oil resources in Figure 20.3. Imagine a world in which everybody had equal access to resources. Some people would have fewer resources than they do now. But many people would have more. In the real world, the difference between rich and poor just keeps growing. Every 20 minutes, the human population adds 3,500 more people. More people need more resources. For example, we now use five times more fossil fuels than we did in 1970. The human population is expected to increase for at least 40 years. What will happen to resource use? How can we protect Earths natural resources? One answer is conservation. This means saving resources. We need to save resources so some will be left for the future. We also need to protect resources from pollution and overuse. When we conserve resources, we also cut down on the trash we produce. Americans throw out 340 million tons of trash each year. We throw out 2.5 million plastic bottles alone every hour! Most of what we throw out ends up in landfills. You can see a landfill in Figure 20.4. In a landfill, all those plastic bottles take hundreds of
Output:
|
any natural resource that will not run out if we use it wisely
| 1
|
NIv2
|
task470_mrqa_question_generation
|
fs_opt
|
You will be given a definition of a task first, then an example. Follow the example to solve a new instance of the task.
Given a context passage, generate a question from the passage such that its answer is shortest continous span from the passage.
In 1582 the united provinces invited francis, duke of anjou to lead them; but after a failed attempt to take antwerp in 1583, the duke left the netherlands again. after the assassination of william of orange (10 july 1584), both henry iii of france and elizabeth i of england declined the offer of sovereignty. however, the latter agreed to turn the united provinces into a protectorate of england (treaty of nonsuch, 1585), and sent the earl of leicester as governor-general. this was unsuccessful and in 1588 the provinces became a confederacy. the union of utrecht is regarded as the foundation of the republic of the seven united provinces, which was not recognized by the spanish empire until the peace of westphalia in 1648.
Solution: In what year did francis, duke of anjou leave the netherlands?
Why? The generated question is perfect. Because the question is based on second sentence of the input passage and its answer is 1583.
New input: One success story in reducing pollutants that harm the atmosphere concerns ozone-destroying chemicals. In 1973, scientists calculated that CFCs could reach the stratosphere and break apart. This would release chlorine atoms, which would then destroy ozone. Based only on their calculations, the United States and most Scandinavian countries banned CFCs in spray cans in 1978. More confirmation that CFCs break down ozone was needed before more was done to reduce production of ozone- destroying chemicals. In 1985, members of the British Antarctic Survey reported that a 50% reduction in the ozone layer had been found over Antarctica in the previous three springs. Two years after the British Antarctic Survey report, the "Montreal Protocol on Substances that Deplete the Ozone Layer" was ratified by nations all over the world. The Montreal Protocol controls the production and consumption of 96 chemicals that damage the ozone layer (Figure 1.1). Hazardous substances are phased out first by developed nations and one decade later by developing nations. More hazardous substances are phased out more quickly. CFCs have been mostly phased out since 1995, although were used in developing nations until 2010. Some of the less hazardous substances will not be phased out until 2030. The Protocol also requires that wealthier nations donate money to develop technologies that will replace these chemicals. Ozone levels over North America decreased between 1974 and 2009. Models of the future predict what ozone levels would have been if CFCs were not being phased out. Warmer colors indicate more ozone. Since CFCs take many years to reach the stratosphere and can survive there a long time before they break down, the ozone hole will probably continue to grow for some time before it begins to shrink. The ozone layer will reach the same levels it had before 1980 around 2068 and 1950 levels in one or two centuries.
Solution:
|
the united states and most scandinavian countries banned ________ that were found to contain cfcs.
| 0
|
NIv2
|
task470_mrqa_question_generation
|
fs_opt
|
Subsets and Splits
No community queries yet
The top public SQL queries from the community will appear here once available.