Datasets:

taln-ls2n
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kpbiomed

id stringlengths 8 8	title stringlengths 1 1.06k	abstract stringlengths 1 13.4k	authors stringlengths 2 63.9k	mesh_terms sequence	year stringclasses 12 values	keyphrases sequence	prmu sequence
31703611	Recommendations for performance optimizations when using GATK3.8 and GATK4.	BACKGROUND Use of the Genome Analysis Toolkit (GATK) continues to be the standard practice in genomic variant calling in both research and the clinic. Recently the toolkit has been rapidly evolving. Significant computational performance improvements have been introduced in GATK3.8 through collaboration with Intel in 20...	['Heldenbrand\|Jacob R\|JR\|', 'Baheti\|Saurabh\|S\|', 'Bockol\|Matthew A\|MA\|', 'Drucker\|Travis M\|TM\|', 'Hart\|Steven N\|SN\|', 'Hudson\|Matthew E\|ME\|', 'Iyer\|Ravishankar K\|RK\|', 'Kalmbach\|Michael T\|MT\|', 'Kendig\|Katherine I\|KI\|', 'Klee\|Eric W\|EW\|', 'Mattson\|Nathan R\|NR\|', 'Wieben\|Eric D\|ED\|', 'Wiepert\|Mathieu\|M\|', 'Wildman\|Derek...	[ "D000465:Algorithms", "D002877:Chromosomes, Human", "D015894:Genome, Human", "D023281:Genomics", "D006239:Haplotypes", "D059014:High-Throughput Nucleotide Sequencing", "D006801:Humans", "D012984:Software" ]	2019	[ "GATK", "Genomic variant calling", "Computational performance", "Parallelization", "Best practices", "Cluster computing" ]	[ "P", "P", "P", "P", "P", "M" ]
27338850	Diffusion-weighted magnetic resonance imaging predicts malignant potential in small hepatocellular carcinoma.	BACKGROUND Poor differentiation and microvascular invasion are indicators of poor outcome after hepatectomy for patients with small hepatocellular carcinoma (HCC). AIMS We investigated whether gadoxetic acid-enhanced and diffusion-weighted magnetic resonance imaging (MRI) could predict these factors before hepatectom...	['Okamura\|Shusuke\|S\|', 'Sumie\|Shuji\|S\|', 'Tonan\|Tatsuyuki\|T\|', 'Nakano\|Masahito\|M\|', 'Satani\|Manabu\|M\|', 'Shimose\|Shigeo\|S\|', 'Shirono\|Tomotake\|T\|', 'Iwamoto\|Hideki\|H\|', 'Aino\|Hajime\|H\|', 'Niizeki\|Takashi\|T\|', 'Tajiri\|Nobuyoshi\|N\|', 'Kuromatsu\|Ryoko\|R\|', 'Okuda\|Koji\|K\|', 'Nakashima\|Osamu\|O\|', 'Torimura\|Takuji\|T\|']	[ "D000328:Adult", "D000368:Aged", "D000369:Aged, 80 and over", "D006528:Carcinoma, Hepatocellular", "D003287:Contrast Media", "D003937:Diagnosis, Differential", "D038524:Diffusion Magnetic Resonance Imaging", "D005260:Female", "D019786:Gadolinium DTPA", "D006498:Hepatectomy", "D006801:Humans", ...	2016	[ "Microvascular invasion", "Apparent diffusion coefficient", "Histological grade", "Gadoxetic acid" ]	[ "P", "P", "P", "M" ]
29961655	Utility of narrow band imaging in the diagnosis of middle turbinate head edema.	PURPOSE Middle turbinate head edema has recently been found to have high specificity for diagnosis of inhalant allergy. However, subtle mucosal edema can be difficult to appreciate under white light endoscopy. Narrow band imaging (NBI) has the potential to demonstrate edema by identifying reduced mucosal vascularity an...	['Wong\|Eugene\|E\|', 'Hamizan\|Aneeza W\|AW\|', 'Alvarado\|Raquel\|R\|', 'Orgain\|Carolyn A\|CA\|', 'Kalish\|Larry\|L\|', 'Sacks\|Raymond\|R\|', 'Harvey\|Richard J\|RJ\|']	[ "D000328:Adult", "D003430:Cross-Sectional Studies", "D004487:Edema", "D004724:Endoscopy", "D005260:Female", "D006801:Humans", "D008297:Male", "D008875:Middle Aged", "D062048:Narrow Band Imaging", "D009297:Nasal Mucosa", "D000075082:Proof of Concept Study", "D065631:Rhinitis, Allergic", "D012...	2018	[ "Narrow", "Band", "Imaging", "Middle", "Turbinate", "Head", "Edema", "Endoscopy", "Rhinitis" ]	[ "P", "P", "P", "P", "P", "P", "P", "P", "U" ]
31900651	Current issues and perspectives in PD-1 blockade cancer immunotherapy.	Programmed cell death 1 (PD-1) signal receptor blockade has revolutionized the field of cancer therapy. Despite their considerable potential for treating certain cancers, drugs targeting PD-1 still present two main drawbacks: the substantial number of unresponsive patients and/or patients showing recurrences, and side ...	['Chamoto\|Kenji\|K\|', 'Hatae\|Ryusuke\|R\|', 'Honjo\|Tasuku\|T\|']	[ "D000074322:Antineoplastic Agents, Immunological", "D060890:B7-H1 Antigen", "D014408:Biomarkers, Tumor", "D060908:CTLA-4 Antigen", "D003131:Combined Modality Therapy", "D006801:Humans", "D007167:Immunotherapy", "D009369:Neoplasms", "D061026:Programmed Cell Death 1 Receptor" ]	2020	[ "Biomarker", "Combination therapy", "Immune checkpoint inhibitor", "Immune metabolism", "Immune-related adverse event" ]	[ "P", "P", "U", "U", "M" ]
29366431	Prednisolone Effects on Urine Cross-Linked N-Telopeptides of Type I Collagen (Ntx) Diurnal Rhythms in Children.	BACKGROUND Recently, methods for mimicking endogenous cortisol rhythms hereby potentially reducing the risk of systemic adverse effects of exogenous corticosteroids have been patented. Methods for sensitive detection of adverse effects on bone turnover of various doses, administration routes and regimens of exogenous c...	['Wolthers\|Ole D\|OD\|', 'Heuck\|Carsten\|C\|']	[ "D000293:Adolescent", "D000893:Anti-Inflammatory Agents", "D015415:Biomarkers", "D001862:Bone Resorption", "D002648:Child", "D002940:Circadian Rhythm", "D024042:Collagen Type I", "D018592:Cross-Over Studies", "D005260:Female", "D006801:Humans", "D008297:Male", "D010330:Patents as Topic", "D0...	2018	[ "Prednisolone", "Ntx", "diurnal rhythms", "children", "bone turnover", "bone resorption", "Administration regimen", "glucocorticoids." ]	[ "P", "P", "P", "P", "P", "P", "R", "M" ]
31616540	Using induced pluripotent stem cells for modeling Parkinson's disease.	Parkinson's disease (PD) is an age-related neurodegenerative disease caused by the progressive loss of dopaminergic (DA) neurons in the substantia nigra. As DA neurons degenerate, PD patients gradually lose their ability of movement. To date no effective therapies are available for the treatment of PD and its pathogene...	['Ke\|Minjing\|M\|', 'Chong\|Cheong-Meng\|CM\|', 'Su\|Huanxing\|H\|']	[]	2019	[ "Induced pluripotent stem cells", "Aging", "Dopaminergic neurons", "Parkinson’s disease", "Somatic cell reprogramming" ]	[ "P", "U", "R", "M", "M" ]
26198278	Atypical presentation of moyamoya disease in an infant with a de novo RNF213 variant.	Variants in RNF213 lead to susceptibility to moyamoya disease, a rare cerebral angiopathy characterized by bilateral stenosis of the internal carotid arteries and development of a compensatory collateral network. We describe a 3-month-old female with seizures, arterial narrowing involving the internal carotid and intra...	['Harel\|Tamar\|T\|', 'Posey\|Jennifer E\|JE\|', 'Graham\|Brett H\|BH\|', 'Walkiewicz\|Magdalena\|M\|', 'Yang\|Yaping\|Y\|', 'Lalani\|Seema R\|SR\|', 'Belmont\|John W\|JW\|']	[ "D000251:Adenosine Triphosphatases", "D000595:Amino Acid Sequence", "D001483:Base Sequence", "D001921:Brain", "D017124:Conserved Sequence", "D019143:Evolution, Molecular", "D059472:Exome", "D005190:Family", "D005260:Female", "D006801:Humans", "D007223:Infant", "D008297:Male", "D008969:Molecu...	2015	[ "moyamoya disease", "whole exome sequencing" ]	[ "P", "P" ]
33563567	The voices of people with an intellectual disability and a carer about orthopaedic and trauma hospital care in the UK: An interpretative phenomenological study.	INTRODUCTION People with intellectual disabilities have a greater prevalence of musculoskeletal conditions and injuries than the general population. Orthopaedic and trauma hospital care has not been investigated with this group who seldom have their voices heard or their experiences valued and interpreted. AIM To und...	['Drozd\|Mary\|M\|', 'Chadwick\|Darren\|D\|', 'Jester\|Rebecca\|R\|']	[ "D017028:Caregivers", "D006761:Hospitals", "D006801:Humans", "D008607:Intellectual Disability", "D009985:Orthopedics", "D036301:Qualitative Research", "D006113:United Kingdom" ]	2021	[ "Orthopaedic", "Trauma", "Hospital experiences", "IPA", "Intellectual/learning disability" ]	[ "P", "P", "P", "U", "M" ]
34800719	KIF11, a plus end-directed kinesin, as a key gene in benzo(a)pyrene-induced non-small cell lung cancer.	Evidence indicates that Benzo(a)pyrenediol-epoxide (BPDE) can damage lung cells, resulting in carcinogenesis with complex mechanisms. We aimed to explore the genes and pathway variations in this process. First, the key gene was screened out and identified through data mining, and then, it was in turn validated by bioin...	['Ling\|Junjun\|J\|', 'Wang\|Yuhong\|Y\|', 'Ma\|Lihai\|L\|', 'Zheng\|Yu\|Y\|', 'Tang\|Hongqu\|H\|', 'Meng\|Lingzhan\|L\|', 'Zhang\|Liang\|L\|']	[]	2021	[ "Lung cancer", "B[a]PDE", "Benzo[a]pyrene", "Biomarkers", "Immunohistochemistry assay" ]	[ "P", "U", "U", "U", "U" ]
31595877	Antenatal HIV screening: results from the National Perinatal Survey, France, 2016.	BackgroundUniversal antenatal HIV screening programmes are an effective method of preventing mother-to-child transmission.AimsTo assess the coverage and yield of the French programme on a nationally representative sample of pregnant women, and predictive factors for being unscreened or missing information on the perfor...	['Tran\|Thi-Chiên\|TC\|', 'Pillonel\|Josiane\|J\|', 'Cazein\|Françoise\|F\|', 'Sommen\|Cécile\|C\|', 'Bonnet\|Camille\|C\|', 'Blondel\|Béatrice\|B\|', 'Lot\|Florence\|F\|']	[ "D000328:Adult", "D003430:Cross-Sectional Studies", "D005260:Female", "D005602:France", "D015658:HIV Infections", "D019538:Health Care Surveys", "D006291:Health Policy", "D006801:Humans", "D018445:Infectious Disease Transmission, Vertical", "D008403:Mass Screening", "D011247:Pregnancy", "D0112...	2019	[ "antenatal HIV screening", "national perinatal survey", "pregnant women", "antenatal care", "maternal characteristics" ]	[ "P", "P", "P", "P", "U" ]
31807400	Nitrogen-vacancy centers in diamond for nanoscale magnetic resonance imaging applications.	The nitrogen-vacancy (NV) center is a point defect in diamond with unique properties for use in ultra-sensitive, high-resolution magnetometry. One of the most interesting and challenging applications is nanoscale magnetic resonance imaging (nano-MRI). While many review papers have covered other NV centers in diamond ap...	['Boretti\|Alberto\|A\|https://orcid.org/0000-0002-3374-0238', 'Rosa\|Lorenzo\|L\|https://orcid.org/0000-0002-9210-5680', 'Blackledge\|Jonathan\|J\|', 'Castelletto\|Stefania\|S\|']	[]	2019	[ "nitrogen-vacancy center", "nanoscale magnetic resonance imaging (nano-MRI)", "nanodiamonds", "optically detected magnetic resonance" ]	[ "P", "P", "U", "M" ]
29288110	Cerebral Radiation Necrosis: An Analysis of Clinical and Quantitative Imaging and Volumetric Features.	BACKGROUND Radiation therapy is an effective treatment for primary brain tumors and intracranial metastases but can occasionally precede new enhancing lesions on imaging studies that are difficult to discern between tumor recurrence (TR) and radiation necrosis (RN). The aim of this study was to identify clinical presen...	['Feng\|Rui\|R\|', 'Loewenstern\|Joshua\|J\|', 'Aggarwal\|Amit\|A\|', 'Pawha\|Puneet\|P\|', 'Gilani\|Ahmed\|A\|', 'Iloreta\|Alfred Marc\|AM\|', 'Bakst\|Richard\|R\|', 'Miles\|Brett\|B\|', 'Bederson\|Joshua\|J\|', 'Costa\|Anthony\|A\|', 'Gupta\|Vishal\|V\|', 'Shrivastava\|Raj K\|RK\|']	[ "D000328:Adult", "D000368:Aged", "D001932:Brain Neoplasms", "D016371:Cranial Irradiation", "D005260:Female", "D006801:Humans", "D008279:Magnetic Resonance Imaging", "D008297:Male", "D008875:Middle Aged", "D009364:Neoplasm Recurrence, Local", "D059906:Neuroimaging", "D011832:Radiation Injuries"...	2018	[ "Radiation necrosis", "Radiation therapy", "Brain tumors", "Tumor recurrence", "Brain necrosis", "Image segmentation" ]	[ "P", "P", "P", "P", "R", "R" ]
33877641	#SayHerName: Should Obstetrics and Gynecology Reckon with the Legacy of JM Sims?	Dr. James Marion Sims has been heralded as the "father of modern gynecology" for his groundbreaking surgical technique to repair post-partum vesicovaginal fistulas (VVF); however, the ethical concerns around his inhumane practices and the contributions of the enslaved women he refined his technique on are rarely recogn...	['Christmas\|Monica\|M\|0000-0001-9640-2992']	[]	2021	[ "JM Sims", "Father of Modern Gynecology", "Vesicovaginal fistula", "Anarcha and Lucy", "Betsey", "Sims speculum" ]	[ "P", "P", "P", "M", "U", "M" ]
24892023	Effect of silica coating on bond strength between a gold alloy and metal bracket bonded with chemically cured resin.	OBJECTIVE The purpose of this study was to evaluate the effects of three different surface conditioning methods on the shear bond strength (SBS) of metal brackets bonded directly to gold alloy with chemically cured resin. METHODS Two hundred ten type III gold alloy specimens were randomly divided into six groups acco...	['Ryu\|Min-Ju\|MJ\|', 'Gang\|Sung-Nam\|SN\|', 'Lim\|Sung-Hoon\|SH\|']	[]	2014	[ "Bonding", "Chemically cured resin", "Biomaterial science", "Silicoating" ]	[ "P", "P", "U", "U" ]
34654485	Developing Personal Resilience Questionnaire for rural doctors: an indigenous approach study in Indonesia.	BACKGROUND Resilience is recognized as a critical component of well-being and is an essential factor in coping with stress. There are issues of using a standardized resilience scale developed for one cultural population to be used in the different cultural populations. This study aimed to create a specific measurement ...	['Handoyo\|Nicholas Edwin\|NE\|http://orcid.org/0000-0002-9191-518X', 'Rahayu\|Gandes Retno\|GR\|', 'Claramita\|Mora\|M\|', 'Keraf\|Marselino K P Abdi\|MKPA\|', 'Octrisdey\|Karol\|K\|', 'Yuniarti\|Kwartarini Wahyu\|KW\|', 'Ash\|Julie\|J\|', 'Schuwirth\|Lambert\|L\|']	[ "D006801:Humans", "D007214:Indonesia", "D011594:Psychometrics", "D015203:Reproducibility of Results", "D011795:Surveys and Questionnaires", "D014177:Translations" ]	2021	[ "Resilience", "Questionnaire", "Rural", "Doctor", "Indonesia", "Linguistic and cultural adaptation" ]	[ "P", "P", "P", "P", "P", "P" ]
23550921	α-Amylase is a potential growth inhibitor of Porphyromonas gingivalis, a periodontal pathogenic bacterium.	BACKGROUND AND OBJECTIVE Porphyromonas gingivalis is a major etiological agent in the development and progression of periodontal diseases. In this study, we isolated a cell growth inhibitor against P. gingivalis species from rice protein extract. MATERIAL AND METHODS The cell growth inhibitor active against P. gingiv...	['Ochiai\|A\|A\|', 'Harada\|K\|K\|', 'Hashimoto\|K\|K\|', 'Shibata\|K\|K\|', 'Ishiyama\|Y\|Y\|', 'Mitsui\|T\|T\|', 'Tanaka\|T\|T\|', 'Taniguchi\|M\|M\|']	[ "D000818:Animals", "D000900:Anti-Bacterial Agents", "D002462:Cell Membrane", "D006801:Humans", "D008826:Microbial Sensitivity Tests", "D008855:Microscopy, Electron, Scanning", "D012275:Oryza", "D055292:Pancreatic alpha-Amylases", "D010510:Periodontal Diseases", "D010936:Plant Extracts", "D016966...	2014	[ "α-amylase", "Porphyromonas gingivalis", "periodontal disease", "bacterial growth inhibition" ]	[ "P", "P", "P", "M" ]
34430825	Update on the safety of anesthesia in young children presenting for adenotonsillectomy.	Tonsillectomy with and without adenoidectomy is a frequently performed surgical procedure in children. Although a common procedure, it is not without significant risk. It is critical for anesthesiologists to consider preoperative, intraoperative, and postoperative patient factors and events to optimize safety, especial...	['McGuire\|Stephanie R\|SR\|', 'Doyle\|Nichole M\|NM\|']	[]	2021	[ "Anesthesia in young children", "Anesthesia for adenotonsillectomy", "Anesthesia safety" ]	[ "P", "R", "R" ]
30853728	Drought attenuates the impact of fish on aquatic macroinvertebrate richness and community composition.	Identifying ecological niche filters that shape species community composition is a critical first step in understanding the relative contributions of deterministic and stochastic processes in structuring communities. Systems with harsh ecological filters often have a more deterministic basis to community structure. Alt...	['McDevitt-Galles\|Travis\|T\|0000-0002-4929-5431', 'Johnson\|Pieter T J\|PTJ\|']	[]	2018	[ "Drought", "Fish", "Macroinvertebrate", "Community Composition", "Niche-Filter" ]	[ "P", "P", "P", "P", "U" ]
25995653	Effects of training and anthropometric factors on marathon and 100 km ultramarathon race performance.	BACKGROUND Marathon (42 km) and 100 km ultramarathon races are increasing in popularity. The aim of the present study was to investigate the potential associations of anthropometric and training variables with performance in these long-distance running competitions. METHODS Training and anthropometric data from a lar...	['Tanda\|Giovanni\|G\|', 'Knechtle\|Beat\|B\|']	[]	2015	[ "performance", "running", "body fat", "training indices", "sports training" ]	[ "P", "P", "P", "P", "M" ]
33198737	DNA sequencing of anatomy lab cadavers to provide hands-on precision medicine introduction to medical students.	BACKGROUND Medical treatment informed by Precision Medicine is becoming a standard practice for many diseases, and patients are curious about the consequences of genomic variants in their genome. However, most medical students' understanding of Precision Medicine derives from classroom lectures. This format does little...	['Anandakrishnan\|Ramu\|R\|', 'Carpenetti\|Tiffany L\|TL\|', 'Samuel\|Peter\|P\|', 'Wasko\|Breezy\|B\|', 'Johnson\|Craig\|C\|', 'Smith\|Christy\|C\|', 'Kim\|Jessica\|J\|', 'Michalak\|Pawel\|P\|', 'Kang\|Lin\|L\|', 'Kinney\|Nick\|N\|', 'Santo\|Arben\|A\|', 'Anstrom\|John\|J\|', 'Garner\|Harold R\|HR\|', 'Varghese\|Robin T\|RT\|http://orcid.org/0000-0001-6244-82...	[ "D000715:Anatomy", "D002102:Cadaver", "D003479:Curriculum", "D004504:Education, Medical, Undergraduate", "D006801:Humans", "D057285:Precision Medicine", "D017422:Sequence Analysis, DNA", "D013337:Students, Medical" ]	2020	[ "DNA sequencing", "Anatomy lab", "Precision medicine", "Exome sequencing", "Clinically informative variants", "Histology" ]	[ "P", "P", "P", "P", "R", "U" ]
25999828	Pre-stimulus BOLD-network activation modulates EEG spectral activity during working memory retention.	Working memory (WM) processes depend on our momentary mental state and therefore exhibit considerable fluctuations. Here, we investigate the interplay of task-preparatory and task-related brain activity as represented by pre-stimulus BOLD-fluctuations and spectral EEG from the retention periods of a visual WM task. Vis...	['Kottlow\|Mara\|M\|', 'Schlaepfer\|Anthony\|A\|', 'Baenninger\|Anja\|A\|', 'Michels\|Lars\|L\|', 'Brandeis\|Daniel\|D\|', 'Koenig\|Thomas\|T\|']	[]	2015	[ "working memory", "frontal-midline theta", "BOLD-ICA", "covariance mapping", "pre-stimulus state", "state dependency", "temporally coherent brain networks" ]	[ "P", "P", "U", "U", "R", "R", "R" ]
29378821	Anterior Pituitary Transcriptome Suggests Differences in ACTH Release in Tame and Aggressive Foxes.	Domesticated species exhibit a suite of behavioral, endocrinological, and morphological changes referred to as "domestication syndrome." These changes may include a reduction in reactivity of the hypothalamic-pituitary-adrenal (HPA) axis and specifically reduced adrenocorticotropic hormone release from the anterior pit...	['Hekman\|Jessica P\|JP\|0000-0002-7296-8307', 'Johnson\|Jennifer L\|JL\|', 'Edwards\|Whitney\|W\|', 'Vladimirova\|Anastasiya V\|AV\|', 'Gulevich\|Rimma G\|RG\|', 'Ford\|Alexandra L\|AL\|', 'Kharlamova\|Anastasiya V\|AV\|', 'Herbeck\|Yury\|Y\|', 'Acland\|Gregory M\|GM\|', 'Raetzman\|Lori T\|LT\|', 'Trut\|Lyudmila N\|LN\|', 'Kukekova\|Anna V\|AV\|0000-000...	[ "D000324:Adrenocorticotropic Hormone", "D000374:Aggression", "D017398:Alternative Splicing", "D000818:Animals", "D001522:Behavior, Animal", "D019295:Computational Biology", "D000071278:Domestication", "D005589:Foxes", "D020869:Gene Expression Profiling", "D005786:Gene Expression Regulation", "D0...	2018	[ "pituitary", "domestication", "Vulpes vulpes", "RNA-seq", "hypothalamic-pituitary-adrenal axis" ]	[ "P", "P", "P", "U", "R" ]
27282083	Search for a reliable model for bisphosphonate-related osteonecrosis of the jaw: establishment of a model in pigs and description of its histomorphometric characteristics.	The pathogenesis of bisphosphonate-related osteonecrosis of the jaw (BRONJ) remains unknown, and the development of a reliable experimental model would help to improve our understanding of it. We used 12 domestic pigs of which 6 made up the experimental group and were treated with zoledronate 4mg intravenously weekly f...	['Mitsimponas\|K T\|KT\|', 'Moest\|T\|T\|', 'Iliopoulos\|C\|C\|', 'Rueger\|T\|T\|', 'Mueller\|C\|C\|', 'Lutz\|R\|R\|', 'Shakib\|K\|K\|', 'Neukam\|F W\|FW\|', 'Schlegel\|K A\|KA\|']	[ "D000818:Animals", "D059266:Bisphosphonate-Associated Osteonecrosis of the Jaw", "D015519:Bone Density", "D050071:Bone Density Conservation Agents", "D004164:Diphosphonates", "D004195:Disease Models, Animal", "D006253:Haversian System", "D006801:Humans", "D008963:Molar", "D010020:Osteonecrosis", ...	2016	[ "Bisphosphonate-Related Osteonecrosis of the Jaws", "Experimental model", "Bisphosphonates" ]	[ "P", "P", "U" ]
30619231	Iron Regulation in Clostridioides difficile.	The response to iron limitation of several bacteria is regulated by the ferric uptake regulator (Fur). The Fur-regulated transcriptional, translational and metabolic networks of the Gram-positive, pathogen Clostridioides difficile were investigated by a combined RNA sequencing, proteomic, metabolomic and electron micro...	['Berges\|Mareike\|M\|', 'Michel\|Annika-Marisa\|AM\|', 'Lassek\|Christian\|C\|', 'Nuss\|Aaron M\|AM\|', 'Beckstette\|Michael\|M\|', 'Dersch\|Petra\|P\|', 'Riedel\|Katharina\|K\|', 'Sievers\|Susanne\|S\|', 'Becher\|Dörte\|D\|', 'Otto\|Andreas\|A\|', 'Maaß\|Sandra\|S\|', 'Rohde\|Manfred\|M\|', 'Eckweiler\|Denitsa\|D\|', 'Borrero-de Acuña\|Jose M\|JM\|', 'Jahn\|M...	[]	2018	[ "iron regulation", "Fur", "metabolism", "cell wall", "polyamine", "iron transport" ]	[ "P", "P", "P", "P", "P", "R" ]
27552340	Symptoms of Depression, Positive Symptoms of Psychosis, and Suicidal Ideation Among Adults Diagnosed With Schizophrenia Within the Clinical Antipsychotic Trials of Intervention Effectiveness.	Suicide is among leading causes of death for adults diagnosed with schizophrenia. While symptoms of depression are consistently supported factors involved in suicidal ideation, findings on the role of positive symptoms of psychosis have been mixed with limited understandings of risk. Accordingly, this study aimed to id...	['Bornheimer\|Lindsay A\|LA\|', 'Jaccard\|James\|J\|']	[ "D000328:Adult", "D014150:Antipsychotic Agents", "D002986:Clinical Trials as Topic", "D003702:Delusions", "D003863:Depression", "D005260:Female", "D006212:Hallucinations", "D006801:Humans", "D008297:Male", "D011618:Psychotic Disorders", "D012559:Schizophrenia", "D012565:Schizophrenic Psycholog...	2017	[ "depression", "psychosis", "suicide", "CATIE" ]	[ "P", "P", "P", "P" ]
34813063	Expression and In Vivo Loading of De Novo Proteins with Tetrapyrrole Cofactors.	Tetrapyrrole cofactors such as heme and chlorophyll imprint their intrinsic reactivity and properties on a multitude of natural proteins and enzymes, and there is much interest in exploiting their functional and catalytic capabilities within minimal, de novo designed protein scaffolds. Here we describe how, using only ...	['Curnow\|Paul\|P\|', 'Anderson\|J L Ross\|JLR\|']	[]	2022	[ "De novo proteins", "Tetrapyrroles", "Heme", "Electron microscopy", "Fluorescence imaging", "In vivo cofactor loading", "Protein expression and purification" ]	[ "P", "P", "P", "R", "R", "R", "M" ]
34724097	Role of Akt isoforms in neuronal insulin signaling and resistance.	The aim of the present study was to determine the role of Akt isoforms in insulin signaling and resistance in neuronal cells. By silencing Akt isoforms individually and in pairs, in Neuro-2a and HT22 cells we observed that, in insulin-sensitive condition, Akt isoforms differentially reduced activation of AS160 and gluc...	['Sharma\|Medha\|M\|', 'Dey\|Chinmoy Sankar\|CS\|http://orcid.org/0000-0003-0667-915X']	[]	2021	[ "Neuronal insulin signaling", "AS160", "Akt2", "Akt3", "Akt1", "Neuronal insulin resistance" ]	[ "P", "P", "P", "P", "P", "R" ]
29749031	Amphiphilic Block Copolymers Directed Interface Coassembly to Construct Multifunctional Microspheres with Magnetic Core and Monolayer Mesoporous Aluminosilicate Shell.	Core-shell magnetic porous microspheres have wide applications in drug delivery, catalysis and bioseparation, and so on. However, it is great challenge to controllably synthesize magnetic porous microspheres with uniform well-aligned accessible large mesopores (>10 nm) which are highly desired for applications involvin...	['Zhang\|Yu\|Y\|', 'Yue\|Qin\|Q\|', 'Yu\|Lei\|L\|', 'Yang\|Xuanyu\|X\|', 'Hou\|Xiu-Feng\|XF\|', 'Zhao\|Dongyuan\|D\|', 'Cheng\|Xiaowei\|X\|', 'Deng\|Yonghui\|Y\|http://orcid.org/0000-0002-0657-9397']	[]	2018	[ "amphiphilic block copolymers", "aluminosilicate", "core-shell", "catalysis", "adsorption", "mesoporous materials", "surface acidity" ]	[ "P", "P", "P", "P", "P", "M", "R" ]
24301325	Artesunate-amodiaquine combination therapy in the absence of malarial parasite infection induces oxidative damage in female rats.	Artesunate-amodiaquine is among the most widely available artemisinin combination therapy used as treatment regimen for uncomplicated Plasmodium falciparum malaria. Our aim was to evaluate clinical routine markers of liver and renal functions, lipid profile levels and lipid peroxidation status in a female mammalian rat...	['Abolaji\|Amos O\|AO\|', 'Osedeme\|Fenose\|F\|', 'Olusemire\|Oluwatosin\|O\|']	[ "D000655:Amodiaquine", "D000818:Animals", "D000962:Antimalarials", "D037621:Artemisinins", "D004338:Drug Combinations", "D004912:Erythrocytes", "D005260:Female", "D007668:Kidney", "D050356:Lipid Metabolism", "D015227:Lipid Peroxidation", "D008099:Liver", "D016778:Malaria, Falciparum", "D0183...	2014	[ "combination therapy", "malaria", "drug misuse", "erythrocyte", "oxidative stress" ]	[ "P", "P", "P", "P", "P" ]
26131613	Molecular Characterization of the Multidrug Resistant Escherichia coli ST131 Clone.	Escherichia coli ST131 is a recently emerged and globally disseminated multidrug resistant clone associated with urinary tract and bloodstream infections in both community and clinical settings. The most common group of ST131 strains are defined by resistance to fluoroquinolones and possession of the type 1 fimbriae fi...	['Schembri\|Mark A\|MA\|', 'Zakour\|Nouri L Ben\|NL\|', 'Phan\|Minh-Duy\|MD\|', 'Forde\|Brian M\|BM\|', 'Stanton-Cook\|Mitchell\|M\|', 'Beatson\|Scott A\|SA\|']	[]	2015	[ "ST131", "urinary tract", "genomics", "virulence", "antibiotic resistance", "plasmid", "FimH", "TraDIS", "uropathogenic Escherichia coli" ]	[ "P", "P", "P", "P", "P", "P", "U", "U", "M" ]
34802898	Differentially expressed proteins in the interaction of Paracoccidioides lutzii with human monocytes.	BACKGROUND Fungi of the genus Paracoccidioides are the etiological agents of paracoccidioidomycosis, a highly prevalent mycosis in Latin America. Infection in humans occurs by the inhalation of conidia, which later revert to the form of yeast. In this context, macrophages are positioned as an important line of defense,...	['Oliveira\|Flamélia Carla Silva\|FCS\|', 'Pessoa\|Wallace Felipe Blohem\|WFB\|', 'Mares\|Joise Hander\|JH\|', 'Freire\|Herbert Pina Silva\|HPS\|', 'Souza\|Ednara Almeida de\|EA\|', 'Pirovani\|Carlos Priminho\|CP\|', 'Romano\|Carla Cristina\|CC\|']	[]	2021	[ "Proteins", "Infection", "Yeast", "Infección", "Levadura", "Micosis sistémica", "Proteínas", "Systemic mycosis" ]	[ "P", "P", "P", "U", "U", "U", "U", "M" ]
33292673	Associations between animal and herd management factors, serological response to three respiratory pathogens and pluck lesions in finisher pigs on a farrow-to-finish farm.	BACKGROUND Serological screening is a common method to monitor antibody response to pathogen exposure, but results could vary due to several factors. This study aimed to quantify animal and management related factors associated with variation in antibody levels in finisher pigs at slaughter, in an Irish farrow-to-finis...	['Fitzgerald\|Rose Mary\|RM\|https://orcid.org/0000-0002-0847-1830', "O'Shea\|Helen\|H\|", 'Manzanilla\|Edgar García\|EG\|https://orcid.org/0000-0002-2301-2560', 'Moriarty\|John\|J\|', 'McGlynn\|Hugh\|H\|', 'Calderón Díaz\|Julia Adriana\|JA\|https://orcid.org/0000-0002-6313-9283']	[]	2020	[ "Serology", "Actinobacillus pleuropneumonia", "Mycoplasma hyopneumoniae", "Swine influenza virus", "Sow parity", "Enzootic pneumonia", "Pleurisy", "All-in/all-out", "Lung lesions" ]	[ "P", "P", "P", "P", "P", "P", "P", "P", "M" ]
29383448	A comparison of CRISPR/Cas9 and siRNA-mediated ALDH2 gene silencing in human cell lines.	Gene knockdown and knockout using RNAi and CRISPR/Cas9 allow for efficient evaluation of gene function, but it is unclear how the choice of technology can influence the results. To compare the phenotypes obtained using siRNA and CRISPR/Cas9 technologies, aldehyde dehydrogenase 2 (ALDH2) was selected as an example. In t...	['Wang\|Fei\|F\|', 'Guo\|Tao\|T\|', 'Jiang\|Hongmei\|H\|', 'Li\|Ruobi\|R\|', 'Wang\|Ting\|T\|', 'Zeng\|Ni\|N\|', 'Dong\|Guanghui\|G\|', 'Zeng\|Xiaowen\|X\|', 'Li\|Daochuan\|D\|', 'Xiao\|Yongmei\|Y\|', 'Hu\|Qiansheng\|Q\|', 'Chen\|Wen\|W\|', 'Xing\|Xiumei\|X\|', 'Wang\|Qing\|Q\|']	[ "D000071396:Aldehyde Dehydrogenase, Mitochondrial", "D064113:CRISPR-Cas Systems", "D005786:Gene Expression Regulation", "D020868:Gene Silencing", "D057809:HEK293 Cells", "D056945:Hep G2 Cells", "D006720:Homozygote", "D006801:Humans", "D009154:Mutation", "D010641:Phenotype", "D034741:RNA, Small I...	2018	[ "CRISPR/Cas9", "ALDH2", "HepG2", "Gene knockout" ]	[ "P", "P", "P", "P" ]
31988860	Nonalcoholic Fatty Liver Diseases among Recently Diagnosed Patients with Diabetes Mellitus and Risk Factors.	Aim Prevalence of obesity and type 2 diabetes mellitus (T2DM), both of which represent are related to nonalcoholic fatty liver disease (NAFLD), is an increasing trend among Asian people. The study aimed to assess the prevalence of NAFLD in T2DM with their risk factors in the Southern part of Pakistan. Materials and m...	['Butt\|Amna S\|AS\|', 'Hamid\|Saeed\|S\|', 'Haider\|Zishan\|Z\|', 'Sharif\|Fatima\|F\|', 'Salih\|Mohammad\|M\|', 'Awan\|Safia\|S\|', 'Khan\|Aatif A\|AA\|', 'Akhter\|Jaweed\|J\|']	[]	2019	[ "Nonalcoholic fatty liver disease", "Diabetes mellitus", "Risk factors", "Prevalence" ]	[ "P", "P", "P", "P" ]
28585391	Understanding mortality rates after hip fracture repair using ASA physical status in the National Hip Fracture Database.	Hip fracture is the most common reason for older patients to need emergency anaesthesia and surgery. Up to one-third of patients die in the year after hip fracture, but this view of outcome may encourage therapeutic nihilism in peri-operative decisions and discussions. We used a multicentre national dataset to examine ...	['Johansen\|A\|A\|', 'Tsang\|C\|C\|', 'Boulton\|C\|C\|', 'Wakeman\|R\|R\|', 'Moppett\|I\|I\|']	[ "D000368:Aged", "D016208:Databases, Factual", "D005260:Female", "D006620:Hip Fractures", "D006801:Humans", "D008297:Male", "D008875:Middle Aged" ]	2017	[ "mortality", "hip fracture", "ASA physical status", "surgery", "older people" ]	[ "P", "P", "P", "P", "M" ]
30648290	Efficacy and safety of 308-nm excimer lamp in the treatment of scalp psoriasis: a retrospective study.	BACKGROUND Scalp psoriasis is a major therapeutic challenge due to the hindrance caused by hair. Treatment with the 308-nm excimer lamp is purported to provide many benefits over conventional phototherapy. This retrospective study evaluates the efficacy, safety, and effective dosage of 308-nm excimer light in the treat...	['Rattanakaemakorn\|Ploysyne\|P\|', 'Phusuphitchayanan\|Phanitchanat\|P\|', 'Pakornphadungsit\|Kallapan\|K\|', 'Thadanipon\|Kunlawat\|K\|', 'Suchonwanit\|Poonkiat\|P\|https://orcid.org/0000-0001-9723-0563']	[ "D000328:Adult", "D000368:Aged", "D005260:Female", "D006801:Humans", "D008297:Male", "D008875:Middle Aged", "D011565:Psoriasis", "D012189:Retrospective Studies", "D012449:Safety", "D012535:Scalp", "D014467:Ultraviolet Therapy" ]	2019	[ "excimer lamp", "scalp psoriasis", "phototherapy", "excimer light", "excimer laser" ]	[ "P", "P", "P", "P", "M" ]
27100924	Prior renovascular hypertension does not predispose to atherosclerosis in mice.	BACKGROUND Hypertension is a major risk factor for development of atherosclerotic cardiovascular disease (ASCVD). Although lowering blood pressure with antihypertensive drugs reduces the increased risk of ASCVD, residual increased risk still remains, suggesting that hypertension may cause chronic changes that promote a...	['Mortensen\|Martin Bødtker\|MB\|', 'Nilsson\|Line\|L\|', 'Larsen\|Tore G\|TG\|', 'Espeseth\|Eirild\|E\|', 'Bek\|Marie\|M\|', 'Bjørklund\|Martin M\|MM\|', 'Hagensen\|Mette K\|MK\|', 'Wolff\|Anne\|A\|', 'Gunnersen\|Stine\|S\|', 'Füchtbauer\|Ernst-Martin\|EM\|', 'Boedtkjer\|Ebbe\|E\|', 'Bentzon\|Jacob F\|JF\|']	[ "D000818:Animals", "D050197:Atherosclerosis", "D001794:Blood Pressure", "D059305:Diet, High-Fat", "D004195:Disease Models, Animal", "D018014:Gene Transfer Techniques", "D006801:Humans", "D006937:Hypercholesterolemia", "D006978:Hypertension, Renovascular", "D007668:Kidney", "D008297:Male", "D05...	2016	[ "Hypertension", "Atherosclerosis", "PCSK9" ]	[ "P", "P", "P" ]
22529802	Cellulitis with leukocytopenia as an initial sign of acute promyelocytic leukemia.	Patients with hematologic malignancies are immunosuppressive and may develop cutaneous or invasive infections as a primary sign of immune suppression. Acute promyelocytic leukemia (acute myeloid leukemia M3) is caused by translocation of reciprocal chromosomal rearrangement t(15;17), which produces an oncogenic protein...	['Sakamoto\|Sachiko\|S\|', 'Oiso\|Naoki\|N\|', 'Emoto\|Masakatsu\|M\|', 'Uchida\|Shusuke\|S\|', 'Hirao\|Ayaka\|A\|', 'Tatsumi\|Yoichi\|Y\|', 'Matsumura\|Itaru\|I\|', 'Kawada\|Akira\|A\|']	[]	2012	[ "Cellulitis", "Leukocytopenia", "Acute promyelocytic leukemia" ]	[ "P", "P", "P" ]
29403643	Down syndrome and microRNAs.	In recent years numerous studies have indicated the importance of microRNAs (miRNA/miRs) in human pathology. Down syndrome (DS) is the most prevalent survivable chromosomal disorder and is attributed to trisomy 21 and the subsequent alteration of the dosage of genes located on this chromosome. A number of miRNAs are ov...	['Brás\|Aldina\|A\|', 'Rodrigues\|António S\|AS\|', 'Gomes\|Bruno\|B\|', 'Rueff\|José\|J\|']	[]	2018	[ "Down syndrome", "microRNAs", "trisomy 21" ]	[ "P", "P", "P" ]
31390272	Ten-Year Epidemiology of Ankle Injuries in Men's and Women's Collegiate Soccer Players.	CONTEXT Data from the National Collegiate Athletic Association (NCAA) Injury Surveillance Program (ISP) have indicated that ankle injuries are the most common injuries among NCAA soccer players. OBJECTIVE To review 10 years of NCAA-ISP data for soccer players' ankle injuries to understand how the time period (2004-20...	['Gulbrandsen\|Matthew\|M\|', 'Hartigan\|David E\|DE\|', 'Patel\|Karan A\|KA\|', 'Makovicka\|Justin L\|JL\|', 'Tummala\|Sailesh V\|SV\|', 'Chhabra\|Anikar\|A\|']	[ "D016512:Ankle Injuries", "D001265:Athletic Injuries", "D005260:Female", "D006801:Humans", "D015994:Incidence", "D008297:Male", "D011379:Prognosis", "D012737:Sex Factors", "D012916:Soccer", "D013334:Students", "D014481:United States", "D014495:Universities", "D055815:Young Adult" ]	2019	[ "soccer", "injury characterization", "national estimates" ]	[ "P", "M", "M" ]
24147265	Acute effects of stochastic resonance whole body vibration.	AIM To investigate the acute effects of stochastic resonance whole body vibration (SR-WBV) training to identify possible explanations for preventive effects against musculoskeletal disorders. METHODS Twenty-three healthy, female students participated in this quasi-experimental pilot study. Acute physiological and psy...	['Elfering\|Achim\|A\|', 'Zahno\|Jasmine\|J\|', 'Taeymans\|Jan\|J\|', 'Blasimann\|Angela\|A\|', 'Radlinger\|Lorenz\|L\|']	[]	2013	[ "Prevention", "Electromyography", "Relaxation", "Musculoskeletal system", "Quasi-experimental study" ]	[ "P", "P", "P", "M", "R" ]
28092205	Effect of polidocanol foam administration into rat peripheral veins on pulmonary parenchyma.	Background Sclerotherapy has been gaining increased acceptance and popularity as an effective therapy for the treatment of varicose veins. This attention has fed growing interest into the safety and potential complications of this procedure. There is no evidence of pulmonary complications from foam sclerotherapy in hum...	['de Moraes Silva\|Melissa A\|MA\|', 'Ferreira\|Rimarcs G\|RG\|', 'de Jesus-Silva\|Seleno G\|SG\|', 'Cardoso\|Rodolfo S\|RS\|', 'Miranda\|Fausto\|F\|']	[ "D000818:Animals", "D005355:Fibrosis", "D006801:Humans", "D007249:Inflammation", "D008168:Lung", "D008171:Lung Diseases", "D008297:Male", "D000077423:Polidocanol", "D011092:Polyethylene Glycols", "D011650:Pulmonary Alveoli", "D051381:Rats", "D017208:Rats, Wistar", "D012501:Saphenous Vein", ...	2018	[ "Foam sclerotherapy", "endovenous technique", "microcirculatory changes", "pathology/histology", "pharmacological agents" ]	[ "P", "U", "M", "M", "U" ]
28187461	Lysosomal accumulation of anticancer drugs triggers lysosomal exocytosis.	We have recently shown that hydrophobic weak base anticancer drugs are highly sequestered in acidic lysosomes, inducing TFEB-mediated lysosomal biogenesis and markedly increased lysosome numbers per cell. This enhanced lysosomal sequestration of chemotherapeutics, away from their intracellular targets, provoked cancer ...	['Zhitomirsky\|Benny\|B\|', 'Assaraf\|Yehuda G\|YG\|']	[ "D000970:Antineoplastic Agents", "D045744:Cell Line, Tumor", "D019008:Drug Resistance, Neoplasm", "D005089:Exocytosis", "D006801:Humans", "D008247:Lysosomes" ]	2017	[ "lysosomes", "lysosomal exocytosis", "chemotherapeutics", "multidrug resistance", "drug sequestration" ]	[ "P", "P", "P", "P", "R" ]
26477519	Rapid screening of edible oils for phthalates using phase-transfer catalyst-assisted hydrolysis and liquid phase microextraction coupled to high performance liquid chromatography-tandem mass spectrometry.	Edible oil is easily contaminated with phthalic acid esters (PAEs). Conventional procedures to analyze individual PAEs require very rigorous experimental conditions that are extremely labor-intensive due to significant procedural contaminations generated by the ubiquitous presence of PAEs in the laboratory environment....	['Liu\|Shuhui\|S\|', 'Liu\|Laping\|L\|', 'Han\|Yangying\|Y\|', 'Sun\|Jingru\|J\|', 'Feng\|Jing\|J\|', 'Wang\|Jin\|J\|', 'Zhong\|Chongming\|C\|']	[ "D002851:Chromatography, High Pressure Liquid", "D004952:Esters", "D006842:Hydrocarbons, Brominated", "D006868:Hydrolysis", "D057230:Limit of Detection", "D059627:Liquid Phase Microextraction", "D010795:Phthalic Acids", "D010938:Plant Oils", "D053719:Tandem Mass Spectrometry" ]	2015	[ "Edible oil", "Phthalic acid", "Phase-transfer catalyst", "Tetrabutylammonium bromide", "Total phthalate" ]	[ "P", "P", "P", "M", "R" ]
31637962	Metamorphosis of a Gerontological Social Work Scholar.	My participation in the Pre-Dissertation Fellows Program (PDFP) was a defining moment in the development of my career. This commentary focuses on how my participation helped me transition from mentee to mentor and from PhD student to faculty member and scholar in gerontological social work and end-of-life care. While m...	['Wallace\|Cara L\|CL\|0000-0002-6739-1910']	[ "D005178:Faculty", "D005260:Female", "D005853:Geriatrics", "D006801:Humans", "D000071252:Mentoring", "D008611:Mentors", "D010379:Peer Group", "D015397:Program Evaluation", "D012947:Social Work", "D013334:Students" ]	2019	[ "Pre-Dissertation Fellows Program", "mentee", "mentors" ]	[ "P", "P", "P" ]
34028963	Effect of auto flash margin on superficial dose in breast conserving radiotherapy for breast cancer.	PURPOSE To investigate the dose-effect of Auto Flash Margin (AFM) on breast cancer's superficial tissues based on the Treatment Planning System (TPS) in the breast-conserving radiotherapy plan. METHODS A total of 16 breast-conserving patients with early stage breast cancer were selected, using the X-ray Voxel Monte C...	['Wang\|Lu\|L\|', 'Qiu\|Gang\|G\|', 'Yu\|Jianhe\|J\|', 'Zhang\|Qunhui\|Q\|', 'Man\|Li\|L\|', 'Chen\|Li\|L\|', 'Zhang\|Xiaoxiao\|X\|', 'Ren\|Qun\|Q\|', 'Xu\|Hongxia\|H\|', 'Hua\|Xiaolong\|X\|']	[ "D000465:Algorithms", "D001943:Breast Neoplasms", "D005260:Female", "D006801:Humans", "D008175:Lung Neoplasms", "D009010:Monte Carlo Method", "D011879:Radiotherapy Dosage", "D011880:Radiotherapy Planning, Computer-Assisted" ]	2021	[ "auto flash margin", "superficial dose", "breast cancer", "XVMC", "inspiratory exercise" ]	[ "P", "P", "P", "P", "M" ]
27235899	Environmental occurrence and ecological risk assessment of organic UV filters in marine organisms from Hong Kong coastal waters.	Organic UV filters, now considered to be emerging contaminants in aquatic ecosystems, are being intensively tracked in environmental waters worldwide. However, their environmental fate and impact of these contaminants on marine organisms remains largely unknown, especially in Asia. This work elucidates the occurrence a...	['Sang\|Ziye\|Z\|', 'Leung\|Kelvin Sze-Yin\|KS\|']	[ "D000818:Animals", "D017756:Aquaculture", "D059001:Aquatic Organisms", "D049872:Bivalvia", "D005399:Fishes", "D006723:Hong Kong", "D013473:Sunscreening Agents", "D014874:Water Pollutants, Chemical" ]	2016	[ "Marine organisms", "Risk quotient", "Global comparison", "Occurrence monitoring", "Ultraviolet filters" ]	[ "P", "P", "U", "M", "M" ]
30227369	The variation of mitochondrial NADH dehydrogenase subunit 4 (mtND4) and molecular dynamics simulation of SNPs among Iranian women with breast cancer.	Breast cancer is the second cause of death among women all around the world. One out of every eight women is diagnosed with breast cancer in Iran. There are many reasons for cancer, one of which is the mutations in the mitochondrial genome observed in most breast cancer studies. However, the aim of this study is to eva...	['Arezi\|Parastoo\|P\|', 'Rezvani\|Zahra\|Z\|']	[ "D014408:Biomarkers, Tumor", "D001943:Breast Neoplasms", "D019143:Evolution, Molecular", "D005260:Female", "D059014:High-Throughput Nucleotide Sequencing", "D006801:Humans", "D007492:Iran", "D056004:Molecular Dynamics Simulation", "D009154:Mutation", "D009245:NADH Dehydrogenase", "D020641:Polymo...	2018	[ "mtND4", "Breast cancer", "Iran", "Genetic changes", "Protein structure change" ]	[ "P", "P", "P", "R", "R" ]
27351940	Immunoglobulin A nephropathy: a pathophysiology view.	BACKGROUND AND AIM IgA nephropathy is one of the leading causes of primary glomerulonephritis worldwide and an important etiology of renal disease in young adults. IgA nephropathy is considered an immune complex-mediated disease. METHODS This review article summarizes recent evidence on the pathophysiology of IgA nep...	['Fabiano\|Rafaela Cabral Gonçalves\|RC\|', 'Pinheiro\|Sérgio Veloso Brant\|SV\|', 'Simões E Silva\|Ana Cristina\|AC\|http://orcid.org/0000-0001-9222-3882']	[ "D000818:Animals", "D005922:Glomerulonephritis, IGA", "D006801:Humans" ]	2016	[ "IgA nephropathy", "Glomerulonephritis", "Anti-glycan antibodies", "Galactose deficiency", "IgA1 glycosylation" ]	[ "P", "P", "R", "M", "M" ]
27554070	Correlation of Breast Ultrasound Classifications with Breast Cancer in Chinese Women.	The aim of this study was to identify potential links between ultrasonographic breast parenchymal patterns and the risk of breast cancer in Chinese women. The population of Chinese women at high risk for breast cancer was explored using the ultrasonographic classification. Ultrasonographic parenchymal patterns were cla...	['Hou\|Xin-Yan\|XY\|', 'Niu\|Hai-Yan\|HY\|', 'Huang\|Xiao-Ling\|XL\|', 'Gao\|Yu\|Y\|']	[ "D000328:Adult", "D000368:Aged", "D000369:Aged, 80 and over", "D001940:Breast", "D001943:Breast Neoplasms", "D002681:China", "D005260:Female", "D006801:Humans", "D008875:Middle Aged", "D016217:Ultrasonography, Mammary" ]	2016	[ "Ultrasound", "Breast cancer", "Breast parenchymal patterns", "Ultrasonographic classification", "Breast tissues", "Density", "Glandular ductal", "High-risk population", "Sonogram", "Ultrasonographic parenchyma" ]	[ "P", "P", "P", "P", "M", "U", "M", "M", "U", "M" ]
22589370	At risk for schizophrenic or affective psychoses? A meta-analysis of DSM/ICD diagnostic outcomes in individuals at high clinical risk.	BACKGROUND The clinical high-risk state for psychosis (HRP) is associated with an enhanced probability of developing a psychotic episode over a relatively short period of time. However, the extent to which different diagnostic types of illness develop remains unclear. METHODS A systematic review was performed to iden...	['Fusar-Poli\|Paolo\|P\|', 'Bechdolf\|Andreas\|A\|', 'Taylor\|Matthew John\|MJ\|', 'Bonoldi\|Ilaria\|I\|', 'Carpenter\|William T\|WT\|', 'Yung\|Alison Ruth\|AR\|', 'McGuire\|Philip\|P\|']	[ "D000341:Affective Disorders, Psychotic", "D001714:Bipolar Disorder", "D003865:Depressive Disorder, Major", "D039721:Diagnostic and Statistical Manual of Mental Disorders", "D018450:Disease Progression", "D005260:Female", "D005500:Follow-Up Studies", "D006801:Humans", "D008297:Male", "D062706:Prod...	2013	[ "psychosis", "schizophrenia", "ARMS", "BS", "SIPS", "affective psychosis", "bipolar", "high risk", "prodromal" ]	[ "P", "P", "U", "U", "U", "R", "U", "R", "U" ]
32523251	Effects of a short-term increase in physical activity on arterial stiffness during hyperglycemia.	We examined the effects of increasing physical activity on arterial stiffness during hyperglycemia. Nineteen glucose-intolerant elderly participated in the study. We randomly assigned 10 participants to increase their daily activity in everyday life, regardless of the time or intensity, for 1 month (PAI group) (age, 74...	['Kobayashi\|Ryota\|R\|', 'Sato\|Kaori\|K\|', 'Takahashi\|Toshihiko\|T\|', 'Asaki\|Kenji\|K\|', 'Iwanuma\|Soichiro\|S\|', 'Ohashi\|Nobuyuki\|N\|', 'Hashiguchi\|Takeo\|T\|']	[]	2020	[ "arterial stiffness", "increased physical activity", "glucose ingestion", "blood glucose", "blood pressure" ]	[ "P", "P", "P", "M", "U" ]
24891268	T wave inversions in leads with ST elevations in patients with acute anterior ST elevation myocardial infarction is associated with patency of the infarct related artery.	OBJECTIVES Following reperfusion therapy, early T wave inversions (TWI) have been shown to be a marker of successful reperfusion. We aimed to evaluate the relationship of TWI on the presenting ECG with spontaneous reperfusion as assessed by coronary angiography in patients with ST elevation (STE) myocardial infarction ...	['Hira\|Ravi S\|RS\|', 'Moore\|Curtiss\|C\|', 'Huang\|Henry D\|HD\|', 'Wilson\|James M\|JM\|', 'Birnbaum\|Yochai\|Y\|']	[ "D056988:Anterior Wall Myocardial Infarction", "D023921:Coronary Stenosis", "D004562:Electrocardiography", "D005260:Female", "D006801:Humans", "D008297:Male", "D008875:Middle Aged", "D009203:Myocardial Infarction", "D015203:Reproducibility of Results", "D012189:Retrospective Studies", "D012680:S...	2014	[ "T wave inversion", "Spontaneous reperfusion", "Primary percutaneous coronary intervention (p-PCI)", "Acute coronary syndromes (ACS)", "Electrocardiogram", "ST elevation myocardial infarction (STEMI)", "TIMI flow grade" ]	[ "P", "P", "P", "M", "U", "R", "M" ]
24114798	Droplet Array Platform for High-Resolution Melt Analysis of DNA Methylation Density.	High-resolution melting (HRM) has garnered significant interest as an analytical technique for a number of applications, including DNA methylation detection, due to its inherent sensitivity and robustness. In this study, we describe a miniaturized assay platform for quantitative methylation density analysis using a mic...	['Athamanolap\|Pornpat\|P\|', 'Shin\|Dong Jin\|DJ\|', 'Wang\|Tza-Huei\|TH\|']	[ "D057205:Automation, Laboratory", "D002138:Calibration", "D018899:CpG Islands", "D019175:DNA Methylation", "D004274:DNA, Recombinant", "D006801:Humans", "D007202:Indicators and Reagents", "D046228:Microarray Analysis", "D046210:Microfluidic Analytical Techniques", "D008904:Miniaturization", "D00...	2014	[ "DNA methylation detection", "melt curve analysis", "miniaturized system" ]	[ "P", "R", "R" ]
26476066	Comparative test of ecological assessment methods of lowland streams based on long-term monitoring data of macrophytes.	Ecological assessment of water courses is required by the European Water Framework Directive (WFD). Assessment by means of macrophytes is impeded by insufficient knowledge on the relations between assessment scores and the dynamics of environmental parameters. Data from a long-term observation of macrophyte dynamics ov...	['Wiegleb\|Gerhard\|G\|', 'Gebler\|Daniel\|D\|', 'van de Weyer\|Klaus\|K\|', 'Birk\|Sebastian\|S\|']	[ "D004463:Ecology", "D017753:Ecosystem", "D004784:Environmental Monitoring", "D010944:Plants", "D045483:Rivers", "D014876:Water Pollution" ]	2016	[ "Ecological status", "Biological assessment", "Indicator value", "Macrophyte indices", "Reference states", "Time series analysis" ]	[ "P", "M", "U", "M", "U", "U" ]
24133478	Virtual sensory feedback for gait improvement in neurological patients.	We review a treatment modality for movement disorders by sensory feedback. The natural closed-loop sensory-motor feedback system is imitated by a wearable virtual reality apparatus, employing body-mounted inertial sensors and responding dynamically to the patient's own motion. Clinical trials have shown a significant g...	['Baram\|Yoram\|Y\|']	[]	2013	[ "sensory feedback", "gait improvement", "virtual reality", "closed-loop gait regulation", "sensory-motor control" ]	[ "P", "P", "P", "M", "M" ]
32389619	Attention allocation to subliminally presented affective faces in high and low social anxiety.	Attention bias to affective stimuli, particularly threatening stimuli, has been well documented, with attention bias to affective faces often reported in populations with social anxiety (SA). However, inconsistencies exist in the literature regarding the direction of the bias, with some studies reporting a bias to atte...	['Duval\|Elizabeth R\|ER\|', 'Lovelace\|Christopher T\|CT\|', 'Filion\|Diane L\|DL\|']	[ "D000293:Adolescent", "D000328:Adult", "D001007:Anxiety", "D000070379:Attentional Bias", "D004576:Electromyography", "D000066499:Facial Recognition", "D005260:Female", "D006801:Humans", "D008297:Male", "D065808:Prepulse Inhibition", "D013216:Reflex, Startle", "D013360:Subliminal Stimulation", ...	2020	[ "Attention", "Anxiety", "Face processing", "Startle blink" ]	[ "P", "P", "R", "M" ]
28558873	Mechanism for ginkgolic acid (15 : 1)-induced MDCK cell necrosis: Mitochondria and lysosomes damages and cell cycle arrest.	Ginkgolic acids (GAs), primarily found in the leaves, nuts, and testa of ginkgo biloba, have been identified with suspected allergenic, genotoxic and cytotoxic properties. However, little information is available about GAs toxicity in kidneys and the underlying mechanism has not been thoroughly elucidated so far. Inste...	['Yao\|Qing-Qing\|QQ\|', 'Liu\|Zhen-Hua\|ZH\|', 'Xu\|Ming-Cheng\|MC\|', 'Hu\|Hai-Hong\|HH\|', 'Zhou\|Hui\|H\|', 'Jiang\|Hui-Di\|HD\|', 'Yu\|Lu-Shan\|LS\|', 'Zeng\|Su\|S\|']	[ "D000818:Animals", "D017209:Apoptosis", "D059447:Cell Cycle Checkpoints", "D002470:Cell Survival", "D004285:Dogs", "D020441:Ginkgo biloba", "D008247:Lysosomes", "D061985:Madin Darby Canine Kidney Cells", "D008928:Mitochondria", "D009336:Necrosis", "D010936:Plant Extracts", "D012459:Salicylates...	2017	[ "Mechanism", "Necrosis", "Cytotoxicity", "Ginkgolic acids (15 : 1)" ]	[ "P", "P", "P", "R" ]
27940259	Inflammation-induced anorexia and fever are elicited by distinct prostaglandin dependent mechanisms, whereas conditioned taste aversion is prostaglandin independent.	Systemic inflammation evokes an array of brain-mediated responses including fever, anorexia and taste aversion. Both fever and anorexia are prostaglandin dependent but it has been unclear if the cell-type that synthesizes the critical prostaglandins is the same. Here we show that pharmacological inhibition or genetic d...	['Nilsson\|Anna\|A\|', 'Wilhelms\|Daniel Björk\|DB\|', 'Mirrasekhian\|Elahe\|E\|', 'Jaarola\|Maarit\|M\|', 'Blomqvist\|Anders\|A\|', 'Engblom\|David\|D\|']	[ "D000818:Animals", "D000855:Anorexia", "D001362:Avoidance Learning", "D051546:Cyclooxygenase 2", "D052246:Cyclooxygenase 2 Inhibitors", "D005334:Fever", "D007249:Inflammation", "D008070:Lipopolysaccharides", "D051379:Mice", "D013649:Taste" ]	2017	[ "Anorexia", "Fever", "Inflammation", "Cyclooxygenase", "Lipopolysaccharide", "Conditioned place aversion" ]	[ "P", "P", "P", "P", "P", "M" ]
30838824	Noble Metal Coated Central Venous Catheters Are Not Superior To Uncoated Catheters In Preventing Infectious And Non-Infectious Complications In Immunocompromised Patients.	Background Patients with haematological malignancies and stem cell transplant recipients are at high risk of opportunistic infections. Little international and no national data is available comparing noble metal coated versus uncoated central venous catheters (CVC) in this special population of severely immunocompromis...	['Iftikhar\|Raheel\|R\|', 'Chaudhry\|Qamar Un Nisa\|QUN\|', 'Satti\|Tariq Mehmood\|TM\|', 'Mahmood\|Syed Kamran\|SK\|', 'Satti\|Humayun Shafique\|HS\|', 'Ghafoor\|Tariq\|T\|', 'Khan\|Mehreen Ali\|MA\|']	[ "D000328:Adult", "D000970:Antineoplastic Agents", "D055499:Catheter-Related Infections", "D002408:Catheters, Indwelling", "D062905:Central Venous Catheters", "D003430:Cross-Sectional Studies", "D004867:Equipment Design", "D005260:Female", "D006402:Hematologic Diseases", "D018380:Hematopoietic Stem...	2018	[ "Central Venous Catheters", "Infection", "Thrombosis" ]	[ "P", "P", "P" ]
31287949	Scanning Probe-Directed Assembly and Rapid Chemical Writing Using Nanoscopic Flow of Phospholipids.	Nanofluidic systems offer a huge potential for discovery of new molecular transport and chemical phenomena that can be employed for future technologies. Herein, we report on the transport behavior of surface-reactive compounds in a nanometer-scale flow of phospholipids from a scanning probe. We have investigated micros...	['Navikas\|Vytautas\|V\|', 'Gavutis\|Martynas\|M\|', 'Rakickas\|Tomas\|T\|http://orcid.org/0000-0002-1231-7545', 'Valiokas\|Ramu Nas\|RN\|http://orcid.org/0000-0003-4807-9136']	[ "D006046:Gold", "D007281:Ink", "D008956:Models, Chemical", "D010743:Phospholipids", "D011327:Printing", "D013438:Sulfhydryl Compounds", "D014956:Writing" ]	2019	[ "nanofluidics", "self-assembled monolayers", "dip-pen nanolithography", "rapid prototyping", "chemical surface patterning", "lipid membrane" ]	[ "P", "P", "P", "P", "R", "M" ]
27242652	Idiopathic Inflammatory Myopathies: Clinical Approach and Management.	Idiopathic inflammatory myopathies (IIM) are a group of chronic, autoimmune conditions affecting primarily the proximal muscles. The most common types are dermatomyositis (DM), polymyositis (PM), necrotizing autoimmune myopathy (NAM), and sporadic inclusion body myositis (sIBM). Patients typically present with sub-acut...	['Malik\|Asma\|A\|', 'Hayat\|Ghazala\|G\|', 'Kalia\|Junaid S\|JS\|', 'Guzman\|Miguel A\|MA\|']	[]	2016	[ "dermatomyositis", "polymyositis", "inclusion body myositis", "myositis specific antibodies", "antiSRP", "idiopathic inflammatory mypathies", "necrotizing myopathy" ]	[ "P", "P", "P", "P", "U", "M", "R" ]
27614563	Benthic surveys of the historic pearl oyster beds of Qatar reveal a dramatic ecological change.	The study aimed to confirm the presence of historic oyster banks of Qatar and code the biotopes present. The research also collated historical records and scientific publications to create a timeline of fishery activity. The oyster banks where once an extremely productive economic resource however, intense overfishing,...	['Smyth\|D\|D\|', 'Al-Maslamani\|I\|I\|', 'Chatting\|M\|M\|', 'Giraldes\|B\|B\|']	[ "D000818:Animals", "D017753:Ecosystem", "D004784:Environmental Monitoring", "D005398:Fisheries", "D019156:Indian Ocean", "D049911:Pinctada", "D011780:Qatar", "D011795:Surveys and Questionnaires", "D014876:Water Pollution" ]	2016	[ "Pearl oyster", "Overfishing", "Anthropogenic disturbance", "Arabian Gulf", "Marine biotope classification", "Pinctada radiata" ]	[ "P", "P", "M", "U", "M", "U" ]
34823527	Acceptability and feasibility of malaria prophylaxis for forest goers: findings from a qualitative study in Cambodia.	BACKGROUND In the Greater Mekong Subregion, adults are at highest risk for malaria, particularly those who visit forests. The absence of effective vector control strategies and limited periods of exposure during forest visits suggest that chemoprophylaxis could be an appropriate strategy to protect forest goers against...	['Jongdeepaisal\|Monnaphat\|M\|', 'Ean\|Mom\|M\|', 'Heng\|Chhoeun\|C\|', 'Buntau\|Thoek\|T\|', 'Tripura\|Rupam\|R\|', 'Callery\|James J\|JJ\|', 'Peto\|Thomas J\|TJ\|', 'Conradis-Jansen\|Franca\|F\|', 'von Seidlein\|Lorenz\|L\|', 'Khonputsa\|Panarasri\|P\|', 'Pongsoipetch\|Kulchada\|K\|', 'Soviet\|Ung\|U\|', 'Sovannaroth\|Siv\|S\|', 'Pell\|Christopher\|C\|', 'M...	[]	2021	[ "Acceptability", "Feasibility", "Malaria", "Prophylaxis", "Forest goer" ]	[ "P", "P", "P", "P", "P" ]
23989188	An investigative peptide-acyclovir combination to control herpes simplex virus type 1 ocular infection.	PURPOSE To investigate the efficacy of a combination treatment composed of the cationic, membrane-penetrating peptide G2, and acyclovir (ACV) in both in vitro and ex vivo models of herpes simplex virus 1 (HSV-1) ocular infection. METHODS The antiviral activity of a combined G2 peptide and ACV therapy (G2-ACV) was ass...	['Park\|Paul J\|PJ\|', 'Antoine\|Thessicar E\|TE\|', 'Farooq\|Asim V\|AV\|', 'Valyi-Nagy\|Tibor\|T\|', 'Shukla\|Deepak\|D\|']	[ "D000212:Acyclovir", "D000818:Animals", "D000890:Anti-Infective Agents", "D023181:Antimicrobial Cationic Peptides", "D000998:Antiviral Agents", "D015153:Blotting, Western", "D002460:Cell Line", "D002522:Chlorocebus aethiops", "D004195:Disease Models, Animal", "D004305:Dose-Response Relationship, D...	2013	[ "acyclovir", "heparan sulfate", "herpes simplex keratitis" ]	[ "P", "U", "M" ]
30836741	Effect of tDCS on Aberrant Functional Network Connectivity in Refractory Hallucinatory Schizophrenia: A Pilot Study.	We aim to investigate the effect of fronto-temporal transcranial direct current stimulation (tDCS) on the interactions among functional networks and its association with psychotic symptoms. In this pilot study, we will determine possible candidate functional networks and an adequate sample size for future research. Sev...	['Yoon\|Youngwoo Bryan\|YB\|', 'Kim\|Minah\|M\|', 'Lee\|Junhee\|J\|', 'Cho\|Kang Ik K\|KIK\|', 'Kwak\|Seoyeon\|S\|', 'Lee\|Tae Young\|TY\|', 'Kwon\|Jun Soo\|JS\|']	[]	2019	[ "Transcranial direct current stimulation", "Auditory hallucinations", "Resting-state fMRI", "Neuroimaging", "Schizophrenia and psychotic disorder" ]	[ "P", "P", "P", "U", "M" ]
32044695	The impact of balance specific physiotherapy, intensity of therapy and disability on static and dynamic balance in people with multiple sclerosis: A multi-center prospective study.	BACKGROUND A high-quality research identifying the best physiotherapeutic approach for the improvement of balance in people with multiple sclerosis is missing. This study compared aspects of balance improvement such as therapy specificity to balance, therapy method and category, country, intensity and medical condition...	['Pavlikova\|M\|M\|', 'Cattaneo\|D\|D\|', 'Jonsdottir\|J\|J\|', 'Gervasoni\|E\|E\|', 'Stetkarova\|I\|I\|', 'Angelova\|G\|G\|', 'Markova\|M\|M\|', 'Prochazkova\|M\|M\|', 'Prokopiusova\|T\|T\|', 'Hruskova\|N\|N\|', 'Reznickova\|J\|J\|', 'Zimova\|D\|D\|', 'Spanhelova\|S\|S\|', 'Rasova\|K\|K\|']	[ "D000328:Adult", "D000368:Aged", "D005081:Exercise Therapy", "D005260:Female", "D006801:Humans", "D008297:Male", "D008875:Middle Aged", "D009103:Multiple Sclerosis", "D010043:Outcome and Process Assessment, Health Care", "D004856:Postural Balance", "D011446:Prospective Studies", "D016037:Singl...	2020	[ "Physiotherapy", "Intensity of therapy", "Static and dynamic balance", "Multiple sclerosis", "Balance specific approach" ]	[ "P", "P", "P", "P", "P" ]
24941982	Ibrutinib: a first in class covalent inhibitor of Bruton's tyrosine kinase.	Ibrutinib (formerly PCI-32765) is a potent, covalent inhibitor of Bruton's tyrosine kinase, a kinase downstream of the B-cell receptor that is critical for B-cell survival and proliferation. In preclinical studies, ibrutinib bound to Bruton's tyrosine kinase with high affinity, leading to inhibition of B-cell receptor ...	['Davids\|Matthew S\|MS\|', 'Brown\|Jennifer R\|JR\|']	[ "D000225:Adenine", "D000077329:Agammaglobulinaemia Tyrosine Kinase", "D000818:Animals", "D000970:Antineoplastic Agents", "D000971:Antineoplastic Combined Chemotherapy Protocols", "D017321:Clinical Trials, Phase I as Topic", "D003131:Combined Modality Therapy", "D004353:Drug Evaluation, Preclinical", ...	2014	[ "ibrutinib", "kinase", "B-cell receptor", "CLL", "MCL", "BTK", "NHL", "lymphocytosis" ]	[ "P", "P", "P", "P", "P", "U", "U", "U" ]
24195032	Effects of intraocular rifampicin on retinal ganglion cell structure: a stereological and histopathological study.	AIM To determine the histopathological changes of rifampicin applied intravitreally on retinal ganglion cells by means of stereological and histopathological methods. METHODS For this study twenty-four New Zealand adult rabbits were divided into four groups (n=6 for each group). 50µg/0.1mL (group 1), 100µg/0.1mL (gro...	['Cakici\|Ozgür\|O\|', 'Aksak\|Selina\|S\|', 'Unal\|Deniz\|D\|', 'Sipal\|Sare\|S\|', 'Keles\|Sadullah\|S\|', 'Dumlu\|Talha\|T\|', 'Karamese\|Murat\|M\|']	[]	2013	[ "rifampicin", "ganglion cells", "stereology", "histopathology" ]	[ "P", "P", "P", "P" ]
32725149	Obeticholic acid ameliorates hepatorenal syndrome in ascitic cirrhotic rats by down-regulating the renal 8-iso-PGF2α-activated COX-TXA2 pathway.	BACKGROUNDS/AIMS The present study explores the potential of chronic treatment with the Foresaid X receptor (FXR) agonist obeticholic acid (OCA), which inhibits oxidative stress-related pathogenesis, in ascitic cirrhotic rats with hepatorenal syndrome (HRS) developed 6 weeks after bile duct ligation (BDL). METHODS Sy...	['Tsai\|Yu-Lien\|YL\|', 'Liu\|Chih-Wei\|CW\|', 'Hsu\|Chien-Fu\|CF\|', 'Huang\|Chia-Chang\|CC\|', 'Lin\|Ming-Wei\|MW\|', 'Huang\|Shiang-Fen\|SF\|', 'Li\|Tzu-Hao\|TH\|', 'Lee\|Kuei-Chuan\|KC\|', 'Hsieh\|Yun-Cheng\|YC\|', 'Yang\|Ying-Ying\|YY\|', 'Lee\|Tzung-Yan\|TY\|', 'Liu\|Hsuan-Miao\|HM\|', 'Huang\|Yi-Hsiang\|YH\|', 'Hou\|Ming-Chih\|MC\|', 'Lin\|Han-Chieh\|HC\|'...	[ "D000818:Animals", "D017209:Apoptosis", "D002460:Cell Line", "D002635:Chenodeoxycholic Acid", "D015237:Dinoprost", "D004353:Drug Evaluation, Preclinical", "D005978:Glutathione", "D006530:Hepatorenal Syndrome", "D008103:Liver Cirrhosis", "D008297:Male", "D018384:Oxidative Stress", "D017207:Rats...	2020	[ "ascites", "oxidative stress", "apoptosis", "chronic hepatorenal syndrome", "cirrhosis", "renal vasoconstriction" ]	[ "P", "P", "P", "R", "U", "M" ]
29371216	Bmal1 in Perivascular Adipose Tissue Regulates Resting-Phase Blood Pressure Through Transcriptional Regulation of Angiotensinogen.	BACKGROUND The perivascular adipose tissue (PVAT) surrounding vessels constitutes a distinct functional integral layer of the vasculature required to preserve vascular tone under physiological conditions. However, there is little information on the relationship between PVAT and blood pressure regulation, including its ...	['Chang\|Lin\|L\|', 'Xiong\|Wenhao\|W\|', 'Zhao\|Xiangjie\|X\|', 'Fan\|Yanbo\|Y\|', 'Guo\|Yanhong\|Y\|', 'Garcia-Barrio\|Minerva\|M\|', 'Zhang\|Jifeng\|J\|', 'Jiang\|Zhisheng\|Z\|', 'Lin\|Jiandie D\|JD\|', 'Chen\|Y Eugene\|YE\|']	[ "D056930:ARNTL Transcription Factors", "D002001:Adipose Tissue, Brown", "D000808:Angiotensinogen", "D000818:Animals", "D001013:Aorta, Thoracic", "D001794:Blood Pressure", "D002940:Circadian Rhythm", "D005838:Genotype", "D008297:Male", "D008810:Mice, Inbred C57BL", "D018345:Mice, Knockout", "D0...	2018	[ "adipose tissue", "blood pressure", "angiotensin II", "circadian rhythm" ]	[ "P", "P", "P", "M" ]
33923675	Laser Discoloration in Acrylic Painting of Visual Art: Experiment and Modeling.	This study discloses a method for painting artwork using a CO2 laser. The continuous-wave laser beam, at a predetermined heat flux and a predetermined number of laser beam passes, mixes and displaces the plurality of colored polymer-based compositions, respectively, by way of melting and vaporizing them. Experiments sh...	['Tamrin\|Khairul Fikri\|KF\|0000-0003-2180-9610', 'Moghadasi\|Kaveh\|K\|', 'Jalil\|Marzie Hatef\|MH\|', 'Sheikh\|Nadeem Ahmed\|NA\|0000-0003-2405-1358', 'Mohamaddan\|Shahrol\|S\|']	[]	2021	[ "laser", "painting", "art", "modeling", "machining", "material", "processing" ]	[ "P", "P", "P", "P", "U", "U", "U" ]
28117128	How consumers of plastic water bottles are responding to environmental policies?	Although plastic induces environmental damages, almost all water bottles are made from plastic and the consumption never stops increasing. This study evaluates the consumers' willingness to pay (WTP) for different plastics used for water packaging. Successive messages emphasizing the characteristics of plastic are deli...	['Orset\|Caroline\|C\|', 'Barret\|Nicolas\|N\|', 'Lemaire\|Aurélien\|A\|']	[ "D000328:Adult", "D000368:Aged", "D003258:Consumer Behavior", "D060766:Drinking Water", "D058735:Environmental Policy", "D005260:Female", "D018857:Food Packaging", "D005602:France", "D006801:Humans", "D007182:Income", "D008297:Male", "D008875:Middle Aged", "D017059:Models, Econometric", "D...	2017	[ "Willingness to pay", "Regulation", "Biodegradable plastic bottles", "Bioplastic bottles", "Information campaign", "Recycling plastic bottles" ]	[ "P", "P", "R", "R", "M", "R" ]
27283535	Implementation of an extended ZINB model in the study of low levels of natural gastrointestinal nematode infections in adult sheep.	BACKGROUND In this study, two traits related with resistance to gastrointestinal nematodes (GIN) were measured in 529 adult sheep: faecal egg count (FEC) and activity of immunoglobulin A in plasma (IgA). In dry years, FEC can be very low in semi-extensive systems, such as the one studied here, which makes identifying a...	['Atlija\|M\|M\|', 'Prada\|J M\|JM\|', 'Gutiérrez-Gil\|B\|B\|', 'Rojo-Vázquez\|F A\|FA\|', 'Stear\|M J\|MJ\|', 'Arranz\|J J\|JJ\|', 'Martínez-Valladares\|M\|M\|']	[ "D000818:Animals", "D005260:Female", "D007070:Immunoglobulin A", "D007411:Intestinal Diseases, Parasitic", "D015233:Models, Statistical", "D009349:Nematode Infections", "D010270:Parasite Egg Count", "D010641:Phenotype", "D012756:Sheep", "D012757:Sheep Diseases" ]	2016	[ "ZINB", "Gastrointestinal nematodes", "Sheep", "Egg count", "IgA", "Prevalence" ]	[ "P", "P", "P", "P", "P", "U" ]
33568995	Pharmacogenetics Guidelines: Overview and Comparison of the DPWG, CPIC, CPNDS, and RNPGx Guidelines.	Many studies have shown that the efficacy and risk of side effects of drug treatment is influenced by genetic variants. Evidence based guidelines are essential for implementing pharmacogenetic knowledge in daily clinical practice to optimize pharmacotherapy of individual patients. A literature search was performed to s...	['Abdullah-Koolmees\|Heshu\|H\|', 'van Keulen\|Antonius M\|AM\|', 'Nijenhuis\|Marga\|M\|', 'Deneer\|Vera H M\|VHM\|']	[]	2020	[ "pharmacogenetics", "guidelines", "DPWG", "CPIC", "CPNDS", "RNPGx", "recommendations", "pharmacogenomics" ]	[ "P", "P", "P", "P", "P", "P", "P", "P" ]
24327493	Off-label drug use in a single-center pediatric cardiac intensive care unit.	BACKGROUND The frequency of off-label drug use and its association with morbidity and mortality in the cardiac intensive care unit (CICU) has not been previously studied. METHODS Patients less than 18 years of age admitted to the CICU from June to August 2008 were retrospectively identified. Patient demographics were...	['Maltz\|Lily A\|LA\|', 'Klugman\|Darren\|D\|', 'Spaeder\|Michael C\|MC\|', 'Wessel\|David L\|DL\|']	[ "D002648:Child", "D002675:Child, Preschool", "D003325:Coronary Care Units", "D003422:Critical Care", "D004812:Epidemiologic Methods", "D005260:Female", "D006331:Heart Diseases", "D006801:Humans", "D007223:Infant", "D015278:Intensive Care Units, Pediatric", "D007902:Length of Stay", "D008297:Ma...	2013	[ "off-label drugs", "pediatrics", "congenital heart disease", "critical care" ]	[ "P", "P", "U", "M" ]
27957206	ICD Implantation Practice Within Europe: How To Explain The Differences Beyond Economy?	Implantable cardioverter defibrillators (ICD) offer the potential to prevent sudden cardiac death and demonstrated a survival benefit in high risk cardiac patients. ICD implantation rates vary significantly throughout the countries all over Europe although there are no major differences in cardiovascular morbidity amon...	['Stella\|Baccillieri Maria\|BM\|', 'Alessandro\|Zorzi\|Z\|']	[]	2015	[ "Implantable Cardioverter Defibrillators", "Sudden Cardiac Death", "Arrhythmic Death", "Primary Prevention", "Secondary Preventionk" ]	[ "P", "P", "M", "M", "U" ]
32459647	Intra-Rater and Inter-Rater Reliability of Tongue Coating Diagnosis in Traditional Chinese Medicine Using Smartphones: Quasi-Delphi Study.	BACKGROUND There is a growing trend in the use of mobile health (mHealth) technologies in traditional Chinese medicine (TCM) and telemedicine, especially during the coronavirus disease (COVID-19) outbreak. Tongue diagnosis is an important component of TCM, but also plays a role in Western medicine, for example in derma...	['Wang\|Zhi Chun\|ZC\|0000-0002-9045-6831', 'Zhang\|Shi Ping\|SP\|0000-0002-6413-5778', 'Yuen\|Pong Chi\|PC\|0000-0002-9343-2202', 'Chan\|Kam Wa\|KW\|0000-0002-3175-1574', 'Chan\|Yi Yi\|YY\|0000-0002-9226-0576', 'Cheung\|Chun Hoi\|CH\|0000-0003-2936-2921', 'Chow\|Chi Ho\|CH\|0000-0002-1894-8903', 'Chua\|Ka Kit\|KK\|0000-0002-0446-3155', 'Hu\|J...	[ "D000086382:COVID-19", "D018352:Coronavirus Infections", "D003697:Delphi Technique", "D006801:Humans", "D008516:Medicine, Chinese Traditional", "D015588:Observer Variation", "D058873:Pandemics", "D010781:Photography", "D011024:Pneumonia, Viral", "D015203:Reproducibility of Results", "D000068997:...	2020	[ "traditional Chinese medicine", "smartphone", "mobile health", "telemedicine", "COVID-19", "tongue image", "Gwet AC2", "machine learning", "oral disease" ]	[ "P", "P", "P", "P", "P", "P", "P", "U", "M" ]
32151263	Serious games for serious crises: reflections from an infectious disease outbreak matrix game.	BACKGROUND While there is widespread recognition of global health failures when it comes to infectious disease outbreaks, there is little discussion on how policy-makers and global health organizations can learn to better prepare and respond. Serious games provide an underutilized tool to promote learning and innovatio...	['Smith\|Julia\|J\|0000-0002-5175-1109', 'Sears\|Nathan\|N\|', 'Taylor\|Ben\|B\|', 'Johnson\|Madeline\|M\|']	[ "D003657:Decision Making", "D004196:Disease Outbreaks", "D000068957:Games, Recreational", "D006801:Humans", "D011050:Policy Making", "D011795:Surveys and Questionnaires" ]	2020	[ "Games", "Outbreaks", "Gender", "Health security", "Training" ]	[ "P", "P", "P", "M", "U" ]
30497226	Endoscope-assisted hemispherotomy: translation of technique from cadaveric anatomical feasibility study to clinical implementation.	OBJECTIVEAppropriately chosen candidates with medically refractory epilepsy may benefit from hemispheric disconnection. Traditionally, this involves a large surgical exposure with significant associated morbidity. Minimally invasive approaches using endoscopic assistance have been described by only a few centers. Here,...	['Wagner\|Kathryn\|K\|', 'Vaz-Guimaraes\|Francisco\|F\|', 'Camstra\|Kevin\|K\|', 'Lam\|Sandi\|S\|']	[ "D059925:Anatomic Landmarks", "D002102:Cadaver", "D002648:Child", "D003337:Corpus Callosum", "D003399:Craniotomy", "D000069279:Drug Resistant Epilepsy", "D005240:Feasibility Studies", "D038421:Hemispherectomy", "D006801:Humans", "D007223:Infant", "D008279:Magnetic Resonance Imaging", "D008297:...	2018	[ "endoscope-assisted", "hemispherotomy", "epilepsy", "endoscopic", "hemispherectomy", "keyhole", "seizure surgery" ]	[ "P", "P", "P", "P", "P", "P", "U" ]
28508022	Impact of Health Literacy on Senior Citizen Engagement in Health Care IT Usage.	Objective: Patient engagement in health care information technology (IT) is required for government reimbursement programs. This research surveyed one older adult group to determine their willingness to use health information from a variety of sources. Health literacy was also measured using the Newest Vital Sign (NVS)...	['Noblin\|Alice M\|AM\|', 'Rutherford\|Ashley\|A\|']	[]	2017	[ "health literacy", "health care IT usage", "patient engagement", "Newest Vital Sign", "eHEALS" ]	[ "P", "P", "P", "P", "P" ]
30676086	Bounds on Identification of Genome Evolution Pacemakers.	Several studies have pointed out that the tight correlation between genes' evolutionary rate is better explained by a model denoted as the	['Snir\|Sagi\|S\|']	[ "D019143:Evolution, Molecular", "D016678:Genome", "D008957:Models, Genetic", "D010802:Phylogeny" ]	2019	[ "Chernoff bounds", "DNA sequence evolution", "chi square distribution", "probabilistic geometrical clustering" ]	[ "M", "M", "U", "U" ]
29945915	Linoleic Acid in Adipose Tissue and Development of Ischemic Stroke: A Danish Case-Cohort Study.	BACKGROUND We investigated the association between the content of linoleic acid in adipose tissue, a biomarker of long-term intake of linoleic acid, and the risk of ischemic stroke and its subtypes. METHODS AND RESULTS The Danish cohort study Diet, Cancer and Health included 57 053 patients aged 50 to 65 years at enr...	['Venø\|Stine Krogh\|SK\|', 'Bork\|Christian Sørensen\|CS\|', 'Jakobsen\|Marianne Uhre\|MU\|', 'Lundbye-Christensen\|Søren\|S\|', 'Bach\|Flemming Winther\|FW\|', 'Overvad\|Kim\|K\|', 'Schmidt\|Erik Berg\|EB\|']	[ "D000368:Aged", "D015415:Biomarkers", "D002545:Brain Ischemia", "D003718:Denmark", "D005260:Female", "D006801:Humans", "D019787:Linoleic Acid", "D008297:Male", "D008875:Middle Aged", "D011379:Prognosis", "D018570:Risk Assessment", "D012307:Risk Factors", "D020521:Stroke", "D050151:Subcutan...	2018	[ "adipose tissue", "ischemic", "stroke", "fatty acid" ]	[ "P", "P", "P", "P" ]
28979769	Single-incision laparoscopic surgery in gynecologic surgery: a single-institutional experience from Saudi Arabia.	Background: Laparoscopy is rapidly replacing laparotomy in the field of gynecologic surgery. Generally, there are limited data concerning the utility of single-incision laparoscopic surgery (SILS) in gynecologic surgery. Specifically, in Saudi Arabia, a third-world country, data are further limited; only one related st...	['Salamah\|Kareemah\|K\|', 'Abuzaid\|Mohammed\|M\|', 'Abu-Zaid\|Ahmed\|A\|https://orcid.org/0000-0003-2286-2181']	[]	2017	[ "single-incision laparoscopic surgery", "Saudi Arabia", "Laparoscopic single-site surgery", "minimally invasive surgery", "Gynecologic oncology" ]	[ "P", "P", "M", "M", "M" ]
28235537	The concentration of desflurane preventing spectral entropy change during surgical stimulation: A prospective randomized trial.	STUDY OBJECTIVE To determine the concentration of desflurane necessary to blunt changes in spectral entropy during surgical incision when two different target-controlled effect-site concentrations of remifentanil (1 and 3ng/ml) were infused. DESIGN Prospective, randomized controlled study. SETTING Operating room of...	['Han\|Sun-Sook\|SS\|', 'Han\|Sunghee\|S\|', 'Kim\|Byung-Gook\|BG\|', 'Kim\|Dong-Ho\|DH\|', 'Ryu\|Jung-Hee\|JH\|']	[ "D000328:Adult", "D000768:Anesthesia, General", "D018685:Anesthetics, Inhalation", "D001794:Blood Pressure", "D000077335:Desflurane", "D017558:Elective Surgical Procedures", "D004569:Electroencephalography", "D005260:Female", "D006339:Heart Rate", "D006801:Humans", "D006993:Hypnotics and Sedativ...	2017	[ "Desflurane", "Spectral entropy", "Surgical stimulation", "Remifentanil", "Hemodynamic response" ]	[ "P", "P", "P", "P", "R" ]
25344370	Ten-year follow-up of the 'minimal MRI lesion' subgroup from the original CHAMPS Multiple Sclerosis Prevention Trial.	BACKGROUND Patients with clinically isolated syndrome (CIS) and characteristic magnetic resonance imaging (MRI) lesions are at high risk for multiple sclerosis (MS). However, patients with a minimal MRI lesion burden (a low T2-hyperintense [low T2] lesion count) may have borderline formal diagnostic criteria, presentin...	['Simon\|J H\|JH\|', 'Kinkel\|R P\|RP\|', 'Kollman\|C\|C\|', "O'Connor\|P\|P\|", 'Fisher\|E\|E\|', 'You\|X\|X\|', 'Hyde\|R\|R\|', '\|\|\|']	[ "D000276:Adjuvants, Immunologic", "D000328:Adult", "D001921:Brain", "D003711:Demyelinating Diseases", "D018450:Disease Progression", "D004311:Double-Blind Method", "D005260:Female", "D005500:Follow-Up Studies", "D006801:Humans", "D000068556:Interferon beta-1a", "D008279:Magnetic Resonance Imagin...	2015	[ "MRI", "CHAMPS", "multiple sclerosis", "clinically isolated syndrome", "disease progression", "CHAMPIONS", "intramuscular interferon beta-1a" ]	[ "P", "P", "P", "P", "P", "P", "U" ]
31068888	Severity of Tinnitus Distress Negatively Impacts Quality of Life in Patients With Vestibular Schwannoma and Mimics Primary Tinnitus.	Objective: Quality of life (QoL) and subjective symptoms are predominantly used to evaluate treatment outcome of patients with vestibular schwannoma (VS). However, for patients undergoing conservative treatment-the most frequently used intervention-the association between QoL and subjective symptoms is unclear. Moreove...	['Kojima\|Takashi\|T\|', 'Oishi\|Naoki\|N\|', 'Nishiyama\|Takanori\|T\|', 'Ogawa\|Kaoru\|K\|']	[]	2019	[ "tinnitus", "quality of life", "prospective studies", "anxiety", "acoustic neuroma", "conservative treatment", "hearing loss", "vertigo" ]	[ "P", "P", "P", "P", "U", "R", "M", "U" ]

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YAML Metadata Warning:The task_categories "text-mining" is not in the official list: text-classification, token-classification, table-question-answering, question-answering, zero-shot-classification, translation, summarization, feature-extraction, text-generation, fill-mask, sentence-similarity, text-to-speech, text-to-audio, automatic-speech-recognition, audio-to-audio, audio-classification, audio-text-to-text, voice-activity-detection, depth-estimation, image-classification, object-detection, image-segmentation, text-to-image, image-to-text, image-to-image, image-to-video, unconditional-image-generation, video-classification, reinforcement-learning, robotics, tabular-classification, tabular-regression, tabular-to-text, table-to-text, multiple-choice, text-ranking, text-retrieval, time-series-forecasting, text-to-video, image-text-to-text, image-text-to-image, image-text-to-video, visual-question-answering, document-question-answering, zero-shot-image-classification, graph-ml, mask-generation, zero-shot-object-detection, text-to-3d, image-to-3d, image-feature-extraction, video-text-to-text, keypoint-detection, visual-document-retrieval, any-to-any, video-to-video, other

YAML Metadata Warning:The task_ids "keyphrase-generation" is not in the official list: acceptability-classification, entity-linking-classification, fact-checking, intent-classification, language-identification, multi-class-classification, multi-label-classification, multi-input-text-classification, natural-language-inference, semantic-similarity-classification, sentiment-classification, topic-classification, semantic-similarity-scoring, sentiment-scoring, sentiment-analysis, hate-speech-detection, text-scoring, named-entity-recognition, part-of-speech, parsing, lemmatization, word-sense-disambiguation, coreference-resolution, extractive-qa, open-domain-qa, closed-domain-qa, news-articles-summarization, news-articles-headline-generation, dialogue-modeling, dialogue-generation, conversational, language-modeling, text-simplification, explanation-generation, abstractive-qa, open-domain-abstractive-qa, closed-domain-qa, open-book-qa, closed-book-qa, text2text-generation, slot-filling, masked-language-modeling, keyword-spotting, speaker-identification, audio-intent-classification, audio-emotion-recognition, audio-language-identification, multi-label-image-classification, multi-class-image-classification, face-detection, vehicle-detection, instance-segmentation, semantic-segmentation, panoptic-segmentation, image-captioning, image-inpainting, image-colorization, super-resolution, grasping, task-planning, tabular-multi-class-classification, tabular-multi-label-classification, tabular-single-column-regression, rdf-to-text, multiple-choice-qa, multiple-choice-coreference-resolution, document-retrieval, utterance-retrieval, entity-linking-retrieval, fact-checking-retrieval, univariate-time-series-forecasting, multivariate-time-series-forecasting, visual-question-answering, document-question-answering, pose-estimation

YAML Metadata Warning:The task_ids "keyphrase-extraction" is not in the official list: acceptability-classification, entity-linking-classification, fact-checking, intent-classification, language-identification, multi-class-classification, multi-label-classification, multi-input-text-classification, natural-language-inference, semantic-similarity-classification, sentiment-classification, topic-classification, semantic-similarity-scoring, sentiment-scoring, sentiment-analysis, hate-speech-detection, text-scoring, named-entity-recognition, part-of-speech, parsing, lemmatization, word-sense-disambiguation, coreference-resolution, extractive-qa, open-domain-qa, closed-domain-qa, news-articles-summarization, news-articles-headline-generation, dialogue-modeling, dialogue-generation, conversational, language-modeling, text-simplification, explanation-generation, abstractive-qa, open-domain-abstractive-qa, closed-domain-qa, open-book-qa, closed-book-qa, text2text-generation, slot-filling, masked-language-modeling, keyword-spotting, speaker-identification, audio-intent-classification, audio-emotion-recognition, audio-language-identification, multi-label-image-classification, multi-class-image-classification, face-detection, vehicle-detection, instance-segmentation, semantic-segmentation, panoptic-segmentation, image-captioning, image-inpainting, image-colorization, super-resolution, grasping, task-planning, tabular-multi-class-classification, tabular-multi-label-classification, tabular-single-column-regression, rdf-to-text, multiple-choice-qa, multiple-choice-coreference-resolution, document-retrieval, utterance-retrieval, entity-linking-retrieval, fact-checking-retrieval, univariate-time-series-forecasting, multivariate-time-series-forecasting, visual-question-answering, document-question-answering, pose-estimation

KPBiomed, A Large-Scale Dataset for keyphrase generation

About

This dataset is made of 5.6 million abstracts with author assigned keyphrases.

Details about the dataset can be found in the original paper: Maël Houbre, Florian Boudin and Béatrice Daille. 2022. A Large-Scale Dataset for Biomedical Keyphrase Generation. In Proceedings of the 13th International Workshop on Health Text Mining and Information Analysis (LOUHI 2022).

Reference (author-assigned) keyphrases are also categorized under the PRMU (Present-Reordered-Mixed-Unseen) scheme as proposed in the following paper:

Florian Boudin and Ygor Gallina. 2021. Redefining Absent Keyphrases and their Effect on Retrieval Effectiveness. In Proceedings of the 2021 Conference of the North American Chapter of the Association for Computational Linguistics: Human Language Technologies, pages 4185–4193, Online. Association for Computational Linguistics.

Text pre-processing (tokenization) is carried out using spacy (en_core_web_sm model) with a special rule to avoid splitting words with hyphens (e.g. graph-based is kept as one token). Stemming (Porter's stemmer implementation provided in nltk) is applied before reference keyphrases are matched against the source text.

Content

The details of the dataset are in the table below:

Split	# documents	# keyphrases by document (average)	% Present	% Reordered	% Mixed	% Unseen
Train small	500k	5.24	66.31	7.16	12.60	13.93
Train medium	2M	5.24	66.30	7.18	12.57	13.95
Train large	5.6M	5.23	66.32	7.18	12.55	13.95
Validation	20k	5.25	66.44	7.07	12.45	14.05
Test	20k	5.22	66.59	7.22	12.44	13.75

The following data fields are available:

id: unique identifier of the document.
title: title of the document.
abstract: abstract of the document.
keyphrases: list of reference keyphrases.
mesh terms: list of indexer assigned MeSH terms if available (around 68% of the articles)
prmu: list of Present-Reordered-Mixed-Unseen categories for reference keyphrases.
authors: list of the article's authors
year: publication year

NB: The present keyphrases (represented by the "P" label in the PRMU column) are sorted by their apparition order in the text (title + text).

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Paper for taln-ls2n/kpbiomed

A Large-Scale Dataset for Biomedical Keyphrase Generation

Paper • 2211.12124 • Published Nov 22, 2022 • 1