ID-PRO
Collection
IDPro (Illuminating the Dark PROteome) • 2 items • Updated
long_format_id stringlengths 18 43 | id stringlengths 6 10 | protein stringclasses 1
value | amino_seq stringlengths 5 10.7k | conversations listlengths 2 2 |
|---|---|---|---|---|
A6T5E6_domain_3_34 | A6T5E6 | Unknown | CPFCFAVDTKVIDSRLVGEGSSVRRRRQCLVC | [
{
"from": "human",
"value": "<protein_sequence>\nWhat protein domain is this sequence?"
},
{
"from": "gpt",
"value": "Based on the sequence, this is a zinc finger region at residues 3-34"
}
] |
Q887Q1_struct_signal_peptide_1 | Q887Q1 | Unknown | MNSPLRRLSTPTLLSLAVALGLSG | [
{
"from": "human",
"value": "<protein_sequence>\nWhat type of structural element does this sequence represent?"
},
{
"from": "gpt",
"value": "Based on the sequence, this is a Signal peptide at residues 1-24."
}
] |
A8H4R5_struct_signal_peptide_1 | A8H4R5 | Unknown | MKKIFTIAALSLPLFCHLPAMA | [
{
"from": "human",
"value": "<protein_sequence>\nWhat type of structural element does this sequence represent?"
},
{
"from": "gpt",
"value": "Based on the sequence, this is a Signal peptide at residues 1-22."
}
] |
C5BH58_struct_transmembrane_region_14 | C5BH58 | Unknown | GSLVGQILVGLVLGIALASFS | [
{
"from": "human",
"value": "<protein_sequence>\nWhat structural feature is this sequence?"
},
{
"from": "gpt",
"value": "Based on the sequence, this is a Transmembrane helix at residues 14-34."
}
] |
Q2A5E0_fullseq_allfeats | Q2A5E0 | Unknown | MSEKKYTFETEVDKLLHLVIHSLYSNREIFLRELVSNSSDAIEKLRYESISNAALNEDDTDYAIRIDFDKDAKTITVSDNGIGMTEEEVIENLGTIAKSGTKKFLESLTGDKSKDNELIGQFGVGFYSSFIVADKVTVRTRKAGQDKSQATKWVSDAQNGFTVEIITKEKRGTEVILHIKKEHLDLLEYHVLKGLVNKYSDCINTPIQMKKVEYDKDGKQTVKDEYETVNNTKAIWLRSKGEVTNEEYQEFYKYISHDFADALMWIHNKVEGNLEYNSLLYIPQNKPFDFWNRDKDYGLSLYVRRVFIMENKELLPPYLR... | [
{
"from": "human",
"value": "<protein_sequence>\nWhat sequence-derivable features are present in this protein?"
},
{
"from": "gpt",
"value": "Based on the sequence, this protein contains:\n 1. A; substrate-binding at residues 1-337\n 2. B at residues 338-554\n 3. C at residues 555-628"
}
] |
Q89AX0_fullseq_allfeats | Q89AX0 | Unknown | MVMHFFLLFVSNILINNFILVRFLGLCPFMGISRTIDSAIGMGLATTCVIVFVSIISWLINFYILIPFHLIHLCTMTYMLIIAVSVQIFEIIVKKVSSTLYRLLGIYLPLITTNCSVLAIPLMNTKLNSNFIESVLYGFSSSLGFFLVLVIFSSIRERISESDVPMYFRGYPIALITASLLAIAFMGFDGLIKF | [
{
"from": "human",
"value": "<protein_sequence>\nWhat sequence-derivable features are present in this protein?"
},
{
"from": "gpt",
"value": "Based on the sequence, this protein contains:\n 1. Transmembrane helix at residues 1-21\n 2. Transmembrane helix at residues 48-68\n 3. Transmembrane h... |
B1LR33_struct_topological_domain_388 | B1LR33 | Unknown | TALWIWQRRH | [
{
"from": "human",
"value": "<protein_sequence>\nWhat can you identify about this sequence region?"
},
{
"from": "gpt",
"value": "Based on the sequence, this is a Topological domain (Cytoplasmic) at residues 388-397."
}
] |
Q9ZED1_struct_signal_peptide_1 | Q9ZED1 | Unknown | MKRILSFIFIILFFNSSYA | [
{
"from": "human",
"value": "<protein_sequence>\nWhat type of structural element does this sequence represent?"
},
{
"from": "gpt",
"value": "Based on the sequence, this is a Signal peptide at residues 1-19."
}
] |
Q6G202_fullseq_allfeats | Q6G202 | Unknown | MPHTQTDAHQNNQENFSSSLISSRPSQPMTLSIQRLDHGQGLELPHYATAGSAGLDLRAALSEEETVILAPGQRALIPTGLIFHLSPGFEAQIRPRSGLALKHGITCLNTPGTIDSDYRGEVKVLLINCGQEDFAIKRGMRIAQTVIAPVLQVNVCALEPQQNESTKNTVGNRGAGGFGSTGHD | [
{
"from": "human",
"value": "<protein_sequence>\nWhat sequence-derivable features are present in this protein?"
},
{
"from": "gpt",
"value": "Based on the sequence, this protein contains:\n 1. substrate/cofactor at positions 96, 109, 113, 123 (4 binding site residues)\n 2. Disordered at residu... |
B1V8K7_domain_574_603 | B1V8K7 | Unknown | VGGLTFRDNRVERYPHLRLTGPSRALRVGD | [
{
"from": "human",
"value": "<protein_sequence>\nWhat type of protein domain does this sequence encode?"
},
{
"from": "gpt",
"value": "Based on the sequence, this is a PbH1 6 at residues 574-603"
}
] |
Q0ABB2_struct_transmembrane_region_152 | Q0ABB2 | Unknown | FMVYWTVLTLAPILMGASLGI | [
{
"from": "human",
"value": "<protein_sequence>\nWhat structural feature is this sequence?"
},
{
"from": "gpt",
"value": "Based on the sequence, this is a Transmembrane helix at residues 152-172."
}
] |
A1WAG1_struct_region_of_interest_284 | A1WAG1 | Unknown | KRQITWLR | [
{
"from": "human",
"value": "<protein_sequence>\nWhat type of structural element does this sequence represent?"
},
{
"from": "gpt",
"value": "Based on the sequence, this is a Interaction with substrate tRNA at residues 284-291."
}
] |
A7H1P4_struct_transmembrane_region_107 | A7H1P4 | Unknown | LALAIATSIDALAVGVSFAFL | [
{
"from": "human",
"value": "<protein_sequence>\nWhat can you identify about this sequence region?"
},
{
"from": "gpt",
"value": "Based on the sequence, this is a Transmembrane helix at residues 107-127."
}
] |
Q49WW4_struct_transmembrane_region_198 | Q49WW4 | Unknown | ATSIGLFCIIMIFALLGFLPF | [
{
"from": "human",
"value": "<protein_sequence>\nWhat type of structural element does this sequence represent?"
},
{
"from": "gpt",
"value": "Based on the sequence, this is a Transmembrane helix at residues 198-218."
}
] |
P58380_fullseq_allfeats | P58380 | Unknown | MAQASGLMNGKRGVIMGVANNRSIAWGIAKALAEAGAEIALTWQGDALKKRVEPLAQELGAFMAGHCDVTDLATIDAVFSALEEKWGKIDFVVHAIAFSDKDELTGRYLDTSRDNFARTMDISVYSFTAVAARADRVMNDGGSILTLTYYGAEKVMPHYNVMGVAKAALEASVRYLAVDLGNRGIRVNAISAGPIKTLAASGIGDFRYILKWNEYNAPLKRTVSIEEVGNSALYLLSDLSSGVTGEVHHVDSGYHTVGMKAVDAPDISVLKD | [
{
"from": "human",
"value": "<protein_sequence>\nWhat sequence-derivable features are present in this protein?"
},
{
"from": "gpt",
"value": "Based on the sequence, this protein contains:\n 1. Proton acceptor at positions 149, 159 (2 active site residues)\n 2. substrate/cofactor: 7 binding sit... |
Q6GDU5_struct_region_of_interest_37 | Q6GDU5 | Unknown | ASEQKTTTVEENGNSATDNKVSETQTTTTNVNTIDETQSYSATATEQPSNATQVTTEEAPKAVQAPQTAQPANVETVKEEVVKEEANPQVKETTQSQDNSGDQRQVDLTPKKATQNQVAETQVEVAQPRTALESKPRVTRSTDVAEAKEASDAKVETGTDVTSKVTVEDE | [
{
"from": "human",
"value": "<protein_sequence>\nWhat type of structural element does this sequence represent?"
},
{
"from": "gpt",
"value": "Based on the sequence, this is a Disordered at residues 37-206."
}
] |
Q607R4_struct_region_of_interest_163 | Q607R4 | Unknown | QRLQR | [
{
"from": "human",
"value": "<protein_sequence>\nWhat structural feature is this sequence?"
},
{
"from": "gpt",
"value": "Based on the sequence, this is a Interaction with substrate tRNA at residues 163-167."
}
] |
P57445_fullseq_domains | P57445 | Unknown | MSLINIHNASLSFSNLQILEKSTFHINKNERVCLIGKNGAGKSTLLKIINKKQDLDEGQIIYKKNTTTAYLEQNNPKNLNISIYDFIALGLKEHEKNKKKHTNEIVKIEKIIELIKLNKNTLLSHLSGGLLRKVALGRVLVREPDILLLDEPTNHLDMKTIKWLETFLKKFSGSILFVSHDRNFIQNVSTRIIDLDRGKLVSWPGDYENFIKLKNESYRIEKIQKQLFDKNLEKEEQWIRKGIKARSTRNEGRVKKLKILQKEQKDYKKIEKINNIEINQSKNYLGKIIFKLDNIDFLVNNKIIIKNFSSIIQHGDKLAL... | [
{
"from": "human",
"value": "<protein_sequence>\nWhat functional domains are present in this protein sequence?"
},
{
"from": "gpt",
"value": "Based on the sequence, this protein contains:\n1. ABC transporter 1 at residues 1-222. four ABC-F proteins have been characterised: EttA, YbiT, YheS, and ... |
A9HRS3_struct_transmembrane_region_155 | A9HRS3 | Unknown | YFVLGSLASGLLLYGSSLVYG | [
{
"from": "human",
"value": "<protein_sequence>\nWhat structural feature is this sequence?"
},
{
"from": "gpt",
"value": "Based on the sequence, this is a Transmembrane helix at residues 155-175."
}
] |
P0AEZ0_struct_topological_domain_104 | P0AEZ0 | Unknown | NIEQFT | [
{
"from": "human",
"value": "<protein_sequence>\nWhat structural feature is this sequence?"
},
{
"from": "gpt",
"value": "Based on the sequence, this is a Topological domain (Periplasmic) at residues 104-109."
}
] |
P0ADE4_struct_transmembrane_region_327 | P0ADE4 | Unknown | YYLVQGGFKR | [
{
"from": "human",
"value": "<protein_sequence>\nWhat structural feature is this sequence?"
},
{
"from": "gpt",
"value": "Based on the sequence, this is a Transmembrane beta strand at residues 327-336."
}
] |
Q7M879_struct_region_of_interest_182 | Q7M879 | Unknown | NIEELSQIITLASIKLKKRCLLESAKEIARRSRGTPRVALRLLRRVRDFAEVANEEEIKIEQARYALHELG | [
{
"from": "human",
"value": "<protein_sequence>\nWhat structural feature is this sequence?"
},
{
"from": "gpt",
"value": "Based on the sequence, this is a Small ATPAse domain (RuvB-S) at residues 182-252."
}
] |
P64299_domain_12_205 | P64299 | Unknown | KIIVLDYGSQYNQLIARRIREFGVFSELKSHKITAQELREINPIGIVLSGGPNSVYADNAFGIDPEIFELGIPILGICYGMQLITHKLGGKVVPAGQAGNREYGQSTLHLRETSKLFSGTPQEQLVLMSHGDAVTEIPEGFHLVGDSNDCPYAAIENTEKNLYGIQFHPEVRHSVYGNDILKNFAISICGARGD | [
{
"from": "human",
"value": "<protein_sequence>\nIdentify the functional domain in this amino acid sequence."
},
{
"from": "gpt",
"value": "Based on the sequence, this is a Glutamine amidotransferase type-1 at residues 12-205. Glutamine amidotransferase (GATase) enzymes catalyse the removal of t... |
Q72JA8_fullseq_allfeats | Q72JA8 | Unknown | MRSDQIKKGLKQAPARAMLRAVGVGDEDFGRPFVGVVNTFTDGMPCNFHLRELAQHLKAGLREAGLFPFEFGAPAISDGISMGTPGMRASLVSREVIADSVELIAQGYLYDGMVGLSACDKTIPGTAMGVIRSGVPGMVLYGGTIAPGEWQGRKLTIVEVFEAVGQRAAGKISEEELLEIERRAIPGPGACGGQYTANTMAMALEALGLSPVGYNAIPAVHPEKERATKEAGKILAWAIAHDWKPKDFLTRKSFLNAVAAVAATGGSTNAVLHLLALAKEAGVELSLDDFDQISRKTPVIADLRPWGTYTAWELYEAGGT... | [
{
"from": "human",
"value": "<protein_sequence>\nWhat functional and structural features can be identified in this sequence?"
},
{
"from": "gpt",
"value": "Based on the sequence, this protein contains:\n 1. Proton acceptor at position 468 (active site)\n 2. substrate/cofactor: 6 binding site r... |
B1WSW1_fullseq_allfeats | B1WSW1 | Unknown | MGTIRLMHAKLHRVQVTEANIDYVGSITIDPILLDKVGILPLEEVDIVNLNNGNRFSTYVIPGETGKGEICPNGGAALLCQPGDLLIIYAYENCDRQEVIQRGHTARVIVADEDNKIQDFLIQTLVPCEDGNKVEFHNSSMIDTILESSQT | [
{
"from": "human",
"value": "<protein_sequence>\nWhat functional and structural features can be identified in this sequence?"
},
{
"from": "gpt",
"value": "Based on the sequence, this protein contains:\n 1. Schiff-base intermediate with substrate; via pyruvic acid at position 26 (active site)\n... |
C5D862_struct_transmembrane_region_236 | C5D862 | Unknown | IVVWVACLLPLPFYLFSLGVP | [
{
"from": "human",
"value": "<protein_sequence>\nWhat can you identify about this sequence region?"
},
{
"from": "gpt",
"value": "Based on the sequence, this is a Transmembrane helix at residues 236-256."
}
] |
C3MZI0_struct_propeptide_1 | C3MZI0 | Unknown | MEELPA | [
{
"from": "human",
"value": "<protein_sequence>\nWhat can you identify about this sequence region?"
},
{
"from": "gpt",
"value": "Based on the sequence, this is a Removed in mature form; by autocatalysis at residues 1-6."
}
] |
P54304_domain_1_233 | P54304 | Unknown | MKSAYIHIPFCEHICHYCDFNKYFIQSQPVDEYLNALEQEMINTIAKTGQPDLKTIFIGGGTPTSLSEEQLKKLMDMINRVLKPSSDLSEFAVEANPDDLSAEKLKILKEAGVNRLSFGVQTFEDDLLEKIGRVHKQKDVFTSFERAREIGFENISLDLMFGLPGQTLKHLEHSINTALSLDAEHYSVYSLIVEPKTVFYNLMQKGRLHLPPQEQEAEMYEIVMSKMEAHGIH | [
{
"from": "human",
"value": "<protein_sequence>\nWhat type of protein domain does this sequence encode?"
},
{
"from": "gpt",
"value": "Based on the sequence, this is a Radical SAM core at residues 1-233. This domain is found in FeMo cofactor biosynthesis protein NifB, PqqA peptide cyclase, Oxyge... |
Q5NXN2_domain_5_267 | Q5NXN2 | Unknown | LIVFDTTLRDGEQSPGASMTRDEKLRIARQLERMRVDVIEAGFPAASNGDFESVRAIAEAIRESTVCGLARANEADIRRAGEAIAPAARGRIHTFIATSPIHMEMKLRMSPDQVVEQAVRAIGWAKEYTDDIEFSAEDAGRSEIDFLCRIFEAVIKAGAKTINVPDTVGYNVPEQYAHTIRTLIERVPGADKVVWSVHCHNDLGLAVANSLAAVMAGARQVECTLNGLGERAGNAALEELVMAVRTRQDVFPCDTRIDATQIV | [
{
"from": "human",
"value": "<protein_sequence>\nWhat protein domain is this sequence?"
},
{
"from": "gpt",
"value": "Based on the sequence, this is a Pyruvate carboxyltransferase at residues 5-267. Pyruvate carboxylase (PC), a member of the biotin-dependent enzyme family, is involved in glucone... |
O28149_struct_transmembrane_region_263 | O28149 | Unknown | LIGVSVIFLAMFAATWVVLRLFG | [
{
"from": "human",
"value": "<protein_sequence>\nWhat can you identify about this sequence region?"
},
{
"from": "gpt",
"value": "Based on the sequence, this is a Transmembrane helix at residues 263-285."
}
] |
Q8DKW4_struct_transmembrane_region_3 | Q8DKW4 | Unknown | IILWLQAVILGLVQGMTEFLP | [
{
"from": "human",
"value": "<protein_sequence>\nWhat structural feature is this sequence?"
},
{
"from": "gpt",
"value": "Based on the sequence, this is a Transmembrane helix at residues 3-23."
}
] |
A3DH97_struct_transmembrane_region_56 | A3DH97 | Unknown | LPVAAVAACFVIVLSFVLMFI | [
{
"from": "human",
"value": "<protein_sequence>\nWhat structural feature is this sequence?"
},
{
"from": "gpt",
"value": "Based on the sequence, this is a Transmembrane helix at residues 56-76."
}
] |
B2JG93_domain_49_139 | B2JG93 | Unknown | PSVVKKDGSRTEFDRRKIVASMQLALRKRPVAADAIDAAASRIEYQLLGSGEREVRSERLGELVMNELRALDTIAYVRFASVYRRFEDVSE | [
{
"from": "human",
"value": "<protein_sequence>\nIdentify the functional domain in this amino acid sequence."
},
{
"from": "gpt",
"value": "Based on the sequence, this is a ATP-cone at residues 49-139. The ATP-cone is an evolutionarily mobile, ATP-binding regulatory domain which is found in a va... |
Q667L9_fullseq_domains | Q667L9 | Unknown | MIKLTHISKVFQQGSRTITALSDVSLHVPAGQIYGVIGASGAGKSTLIRCANMLERPTSGQVLVDGQDLTTLSEGQLTRARRQIGMIFQHFNLLSSRTVYGNIALPLELDNTSRADIKKRVNELLDLVGLTDKQDAYPANLSGGQKQRVAIARALASNPKVLLCDEATSALDPATTRSILELLKDINRRLGLTILLITHEMDVVKRICDQVAVISEGKLIEKDSVSEVFSHPKTPLAQQFIQSTLHLDIPEDYAKRMSPEPTVDHVPLLKLEFTGKSVDAPLISQAVRRFNIDIGILSSQMDYAGGVKFGVMLAELHGDV... | [
{
"from": "human",
"value": "<protein_sequence>\nWhat domains can be recognized from this protein sequence?"
},
{
"from": "gpt",
"value": "Based on the sequence, this protein contains:\n1. ABC transporter at residues 2-241. This entry represents a conserved region found in a group of related ATP... |
A3NYA9_struct_transmembrane_region_253 | A3NYA9 | Unknown | FAWYRIAFGLFVLLVGYSGWI | [
{
"from": "human",
"value": "<protein_sequence>\nWhat can you identify about this sequence region?"
},
{
"from": "gpt",
"value": "Based on the sequence, this is a Transmembrane helix at residues 253-273."
}
] |
A1JPL6_struct_transmembrane_region_48 | A1JPL6 | Unknown | FIAVICGLAGYALSMLCWFFA | [
{
"from": "human",
"value": "<protein_sequence>\nWhat type of structural element does this sequence represent?"
},
{
"from": "gpt",
"value": "Based on the sequence, this is a Transmembrane helix at residues 48-68."
}
] |
Q03BE8_fullseq_allfeats | Q03BE8 | Unknown | MYKRYKDVSLILKIVIGIIVGAVLGVMVPSWSFIDVLGKLFVGALKAIAPLLVFLLIMSAISKYRSGAKNHFGTVIVLYLSATLFSSIAAVAVSYLFPIKLVLPGAMKIAESAPKDLGTVVTSLLTNAVANPISALVEGNYLAILFWSLLIGSGLRLTSAVTKKVVTELADTVSAVAQNVIQFAPFGIVGLLHESLSKTGVKGVMAYGQLLMLLVATMVFVYLVVYPFMVWLMTRQNPYPLTFWTLKVSGIPAFFTRSGAVNIPINLKASKDLGLNEESYAISIPLGGSANSGGAAITVSIMTLATANTMGVHVSIFLAL... | [
{
"from": "human",
"value": "<protein_sequence>\nWhat functional and structural features can be identified in this sequence?"
},
{
"from": "gpt",
"value": "Based on the sequence, this protein contains:\n 1. Transmembrane helix at residues 14-34\n 2. Transmembrane helix at residues 41-61\n 3. ... |
Q4VFY6_struct_transmembrane_region_147 | Q4VFY6 | Unknown | ILLMAGIAAGFGAVFGTPIAG | [
{
"from": "human",
"value": "<protein_sequence>\nWhat structural feature is this sequence?"
},
{
"from": "gpt",
"value": "Based on the sequence, this is a Transmembrane helix at residues 147-167."
}
] |
P9WIT0_struct_region_of_interest_28 | P9WIT0 | Unknown | AHDEELTGPPQKPAYAAKPA | [
{
"from": "human",
"value": "<protein_sequence>\nWhat can you identify about this sequence region?"
},
{
"from": "gpt",
"value": "Based on the sequence, this is a Disordered at residues 28-47."
}
] |
Q2FXZ2_struct_region_of_interest_525 | Q2FXZ2 | Unknown | ENIGEEDKKSAEEKKDALKT | [
{
"from": "human",
"value": "<protein_sequence>\nWhat can you identify about this sequence region?"
},
{
"from": "gpt",
"value": "Based on the sequence, this is a Disordered at residues 525-544."
}
] |
C3MYP4_struct_region_of_interest_58 | C3MYP4 | Unknown | LPQGRLRKDTPRDPLDRENAL | [
{
"from": "human",
"value": "<protein_sequence>\nWhat can you identify about this sequence region?"
},
{
"from": "gpt",
"value": "Based on the sequence, this is a Disordered at residues 58-78."
}
] |
P32715_fullseq_allfeats | P32715 | Unknown | MSALNSLPLPVVRLLAFFHEELSERRPGRVPQTVQLWVGCLLVILISMTFEIPFVALSLAVLFYGIQSNAFYTKFVAILFVVATVLEIGSLFLIYKWSYGEPLIRLIIAGPILMGCMFLMRTHRLGLVFFAVAIVAIYGQTFPAMLDYPEVVVRLTLWCIVVGLYPTLLMTLIGVLWFPSRAISQMHQALNDRLDDAISHLTDSLAPLPETRIEREALALQKLNVFCLADDANWRTQNAWWQSCVATVTYIYSTLNRYDPTSFADSQAIIEFRQKLASEINKLQHAVAEGQCWQSDWRISESEAMAARECNLENICQTLL... | [
{
"from": "human",
"value": "<protein_sequence>\nWhat sequence-derivable features are present in this protein?"
},
{
"from": "gpt",
"value": "Based on the sequence, this protein contains:\n 1. Transmembrane helix at residues 43-63\n 2. Transmembrane helix at residues 75-95\n 3. Transmembrane ... |
Q4L7H2_fullseq_allfeats | Q4L7H2 | Unknown | MVKESIPKEGENIKIQSYKHDGNIHRVWSETTILKGTDHVIIGGNDHTLVTESDGRTWITREPAIVYFHSEFWFNVICMFREDGIYYYCNLSSPFVCDEEALKYIDYDLDIKVYPNGKYHLLDEDEYEQHMNQMNYPHDIDVILRRNVDILQQWIEQKKGPFAPDFIKVWKERYKKIRNY | [
{
"from": "human",
"value": "<protein_sequence>\nWhat functional and structural features can be identified in this sequence?"
},
{
"from": "gpt",
"value": "Based on the sequence, this protein contains:\n 1. Proton donor at position 26 (active site)\n 2. substrate/cofactor: 7 binding site resid... |
D3FI09_domain_582_649 | D3FI09 | Unknown | DYKSIFQEIIHSTGLNMKIHYERTYDRQKNLHTVSLYAGGIMYGEGKDSSTHKAEIKAAKEAISKFRG | [
{
"from": "human",
"value": "<protein_sequence>\nWhat type of protein domain does this sequence encode?"
},
{
"from": "gpt",
"value": "Based on the sequence, this is a DRBM at residues 582-649"
}
] |
Q2NVN8_domain_291_542 | Q2NVN8 | Unknown | TIGMVGKYIALPDAYKSVIEALKHAGLKNRLTVNIRLIDSQDVETRGVEILKDLDAILIPGGFGYRGVEGKILTAQYAREQNIPYLGICLGMQVALIEFARHVAGMQDANSTEFVPDCKYPVVALITEWRDEDGNVEMRSEQSHLGGTMRLGSQLCHLADDSLARSLYGEATILERHRHRYEVNNMLLKHLESAGLRVAGWSGDHKLVEIIEYPDHPWFVASQFHPEFTSTPRDGHPLFAGLVKAAGEYQKR | [
{
"from": "human",
"value": "<protein_sequence>\nWhat type of protein domain does this sequence encode?"
},
{
"from": "gpt",
"value": "Based on the sequence, this is a Glutamine amidotransferase type-1 at residues 291-542. Glutamine amidotransferase (GATase) enzymes catalyse the removal of the a... |
A9MA67_fullseq_allfeats | A9MA67 | Unknown | MAIERTFSMIKPDATRRNLTGAIIAKLEEAGLRVVASKRVWMSRREAEGFYAVHKDRPFFGELVEFMSSGPTVVQVLEGENAIAKNREVMGATNPANADEGTIRKTFALSIGENSVHGSDAPETAAEEIAYWFSGTEIVG | [
{
"from": "human",
"value": "<protein_sequence>\nWhat sequence-derivable features are present in this protein?"
},
{
"from": "gpt",
"value": "Based on the sequence, this protein contains:\n 1. Pros-phosphohistidine intermediate at position 117 (active site)\n 2. substrate/cofactor: 6 binding s... |
Q66FA1_domain_4_103 | Q66FA1 | Unknown | TNRLVLSGTVCKTPVRKVSPSGIPHCQFVLEHRSTQQEAGFSRQTWCRMPIVVSGQQSQALTHSITVGSQLTVEGFISCHQGRNGLNKLVLHAEQIEFID | [
{
"from": "human",
"value": "<protein_sequence>\nWhat type of protein domain does this sequence encode?"
},
{
"from": "gpt",
"value": "Based on the sequence, this is a SSB at residues 4-103"
}
] |
A8GJ50_fullseq_allfeats | A8GJ50 | Unknown | MKKILALLVIAPLLISCSGKKNTEVNEALVKDTNGFEILMGQFAHNIENIWGLNEVLIAGPKDYVKYTDQYQTRSHINFDSGAITIETIATTDPAAHLRQAIISTLLMGDDPGSIDLYSDVNDIQISKEPFLYGQVLDNKGAPIRWEWRAAHFADYLVQTKLQKRTSGLHVIYSVTIQLVPNHLDKRAHKYLPMVRKASEKYGVEESLILAIMQTESSFNPYAVSGSDALGLMQVVQHTAGKDVFQMRGKWGKPSRSYLFDPENNIDTGTAYLAILQNNYLGGIQNPTSRRYAVITAYNGGAGSVLRVFSSDRTRAVGII... | [
{
"from": "human",
"value": "<protein_sequence>\nWhat functional and structural features can be identified in this sequence?"
},
{
"from": "gpt",
"value": "Based on the sequence, this protein contains:\n 1. N-palmitoyl cysteine at position 17 (lipid moiety-binding region)\n 2. S-diacylglycerol... |
A7ME23_struct_transmembrane_region_356 | A7ME23 | Unknown | ALLLVTVTLSMMTTPLVMKGI | [
{
"from": "human",
"value": "<protein_sequence>\nWhat type of structural element does this sequence represent?"
},
{
"from": "gpt",
"value": "Based on the sequence, this is a Transmembrane helix at residues 356-376."
}
] |
P76464_struct_signal_peptide_1 | P76464 | Unknown | MDTQRFQSQFHWHLSFKFSGAIAACLSLSLVGTGLANA | [
{
"from": "human",
"value": "<protein_sequence>\nWhat can you identify about this sequence region?"
},
{
"from": "gpt",
"value": "Based on the sequence, this is a Signal peptide at residues 1-38."
}
] |
P94283_fullseq_allfeats | P94283 | Unknown | MPKLEIYKNLFLDKIGKNFTNLEISELLEPFKAEFDGFDESSGKIKIEFNDTNRPDLWSYLGLARQIKTYFFGEMPYYDFFSKKGDFKKFYGEILVDGKMSQIRPFIFGFLAKGLIINDKMLETLIQFQEKLCQNYGQKRRRIAMGMYNSNFIKFPISYIASSPNHKFVPFGMDYELSLLEINEKHPKGLEYSHIIKNFDKFPLLLDDNNNVVSYPPIINSNNIGSLKVGDTDLFVEVTGIDFEATLLALSIAACDFYDMGFEILPVKTVFREPFNLDFKELVCPYYFQEEVEFNVENINRLLGSNLTLERICLSLKKMG... | [
{
"from": "human",
"value": "<protein_sequence>\nWhat sequence-derivable features are present in this protein?"
},
{
"from": "gpt",
"value": "Based on the sequence, this protein contains:\n 1. B5 at residues 287-362. Domain B5 is found in phenylalanine-tRNA synthetase beta subunits. This domain... |
B5YJT0_fullseq_domains | B5YJT0 | Unknown | MKIYYDTDVNTDILKGKKIAIIGYGSQGHAHANNLKDSGFDVIVGVRKGKSWEKAENAGLTVMTVADASKMADIIMILTPDELQADLYKNEIEPNIKKGAFLAFAHGFNIHFGQIVPSSDINIFMVAPKGPGHLVRSEYLKGMGVPCLMAVHQDPSGITKDVALAYAVGIGGGRAGIIETTFKDETETDLFGEQVVLCGGLTALITAAYETLVEAGYPPELAYFECLHEVKLIADLIYEGGISTMRYSISNTAQYGDLTRGPRVINSSVKAEMKKILNEIQSGQFAKEWILECKVGKPTFNALTKQGEEHPIEKVGEKLR... | [
{
"from": "human",
"value": "<protein_sequence>\nWhat functional domains are present in this protein sequence?"
},
{
"from": "gpt",
"value": "Based on the sequence, this protein contains:\n1. KARI N-terminal Rossmann at residues 1-180. Ketol-acid reductoisomerase (KARI; ), also known as acetohyd... |
F0QYK7_fullseq_allfeats | F0QYK7 | Unknown | MKAVTVIPGIPESLRLMDVSKPNPNKGQVLLKPIRVGVCGTDKEIIEGRYGKAPEGNQYLILGHEAVAEVVEIGDGVDNAGVGDIVVPTVRRPLNCDLPVDFCPVGHYLEHGIWGLHGHAAEYSVTDAKYLVKVPKEIVDVAVLTEPLSVVEKGIDMAMRIGQARFDWKPRTALVLGAGPVGLLATMVLRLMGLSTVTTATRPPDSLKAKLVKELGGTYVDSAVGQISGEFDIVVEATGSPQVINEGLGHIAPNGVYVLLGVYPSGGSLNNLGELMTSVVLNNKVIVGSVNAGIKHFEMALEHLRRAKDEFNNWPAKLIT... | [
{
"from": "human",
"value": "<protein_sequence>\nWhat functional and structural features can be identified in this sequence?"
},
{
"from": "gpt",
"value": "Based on the sequence, this protein contains:\n 1. substrate/cofactor: 11 binding site residues at positions 39, 41, 64, ... 291"
}
] |
Q79LY0_fullseq_allfeats | Q79LY0 | Unknown | MNPLQPIQHSITNSQMSGGQQLEAEGSQAHNSYSHPDRISLSQLSQSAHLALDHLSTQPNTDHQRVASLVRNAVQDGKFQLQSSNDTQVTYKTSVCPPANADTMGAAHLINNELTVQARLNDQLEYDIVSAHLYGPSEAISIDASSPPSANDLASSGLSERTHLGMNRVLLRYAVPPRETEDQCVMVIDKMPPPKHGKMSFFRTTNDLSKLPLGMETGGLSDLKLAGCERISSVEQVKSIRAALGGGPLTVLDLREESHAIVNGLPITLRGPMDWANAGLSQVDGAARESAMITELKRTKSLTLVDANYVKGKKSNPQTT... | [
{
"from": "human",
"value": "<protein_sequence>\nWhat functional and structural features can be identified in this sequence?"
},
{
"from": "gpt",
"value": "Based on the sequence, this protein contains:\n 1. Tyrosine-protein phosphatase at residues 143-468. This superfamily represents a domain f... |
A8FX10_domain_41_265 | A8FX10 | Unknown | NEVQISRLLSIKTGACPEDCKYCPQSARYDTGLEKERLIEIEKVLTEARSAKAAGASRFCMGAAWRNPHARDMPYLKDMVSEVKAMGMETCMTLGMLSGTQAEELAEAGLDYYNHNLDTSPEYYGEIITTRTYQDRLDTLSNVRSAGMKVCSGGIVGMGEQASDRAGLLQQLANMEQHPDSVPINMLVKVAGTPFENLDDLDPLEFVRTIAVARIIMPHSRVRLS | [
{
"from": "human",
"value": "<protein_sequence>\nWhat protein domain is this sequence?"
},
{
"from": "gpt",
"value": "Based on the sequence, this is a Radical SAM core at residues 41-265. This domain is found in FeMo cofactor biosynthesis protein NifB, PqqA peptide cyclase, Oxygen-independent co... |
P96593_struct_transmembrane_region_30 | P96593 | Unknown | LLPFLGPAFIAAIAYIDPGNF | [
{
"from": "human",
"value": "<protein_sequence>\nWhat structural feature is this sequence?"
},
{
"from": "gpt",
"value": "Based on the sequence, this is a Transmembrane helix at residues 30-50."
}
] |
P41086_struct_topological_domain_90 | P41086 | Unknown | EDYINCHKLR | [
{
"from": "human",
"value": "<protein_sequence>\nWhat can you identify about this sequence region?"
},
{
"from": "gpt",
"value": "Based on the sequence, this is a Topological domain (Cytoplasmic) at residues 90-99."
}
] |
Q5M0J9_fullseq_domains | Q5M0J9 | Unknown | MNLTDYVKTVSIEDFGWKFKHQALWNKRLRTTGGRFFPKDGHLDFNPKLYEEHGLETFRKIVRHELCHYHLYFQGKGCKHGDRDFKDLLARVDGLRYAPKMRNQAENYFLYQCQSCGHTYRRKRRVNTQKFGCGLCQGKLIFLNQS | [
{
"from": "human",
"value": "<protein_sequence>\nWhat domains can be recognized from this protein sequence?"
},
{
"from": "gpt",
"value": "Based on the sequence, this protein contains:\n1. SprT-like at residues 6-141. This entry represents a domain found in SprT , which is a regulator of bolA ge... |
C3MW45_fullseq_allfeats | C3MW45 | Unknown | MRLRHVVSSLDLTRDDYFRIFELADKFSNVKKLNYLSGKVVSLAFFEPSTRTAQSFHTAAIKLGADVIGFASEESTSIAKGENLADTIRMLNNYSNCIVMRHKFDGAALFASEISDIPIINAGDGKHEHPTQALIDLYTIYKVFGEIDGRTFGLLGDLKYARTVNSLLRALTRFKPKKIFLISPSQLKVRREILDGLNYPVIETENPYDVIQDIDVLYVTRIQKERFVDELEYEKVKESYVVDLKLVNMMKKDGIILHPLPRVTEIDRKVDKTTNAKYFYQASLAVPVRMALFYEVLGERKDD | [
{
"from": "human",
"value": "<protein_sequence>\nWhat sequence-derivable features are present in this protein?"
},
{
"from": "gpt",
"value": "Based on the sequence, this protein contains:\n 1. substrate/cofactor: 10 binding site residues at positions 51, 52, 80, ... 261"
}
] |
Q8EJQ5_domain_243_390 | Q8EJQ5 | Unknown | KMRLLLTLIEEDWPEKAIVFSNTKHSCENLWSWLEGDGHRVGLLTGDVPQKKRIRILEQFTQGQLDILVATDVAARGLHISDVSHVYNYDLPDDCEDYVHRIGRTGRAGNKGVSVSFACEEYALNLPAIETYINHSIPVSNYDRDALL | [
{
"from": "human",
"value": "<protein_sequence>\nWhat type of protein domain does this sequence encode?"
},
{
"from": "gpt",
"value": "Based on the sequence, this is a Helicase C-terminal at residues 243-390. Helicases have been classified in 5 superfamilies (SF1-SF5). For the two largest groups... |
Q8ZP49_struct_topological_domain_240 | Q8ZP49 | Unknown | RLYMLIRQ | [
{
"from": "human",
"value": "<protein_sequence>\nWhat structural feature is this sequence?"
},
{
"from": "gpt",
"value": "Based on the sequence, this is a Topological domain (Cytoplasmic) at residues 240-247."
}
] |
B5R0P4_fullseq_domains | B5R0P4 | Unknown | MQLTSFTDYGLRALIYMASLPDGRMTSISEVTEVYGVSRNHMVKIINQLSRAGFVTAVRGKNGGIRLGKPANTICIGDVVRELEPLSLVNCSSEFCHITPACRLKQALSKAVQSFLKELDNYTLADLVEENQPLYKLLLVE | [
{
"from": "human",
"value": "<protein_sequence>\nWhat functional domains are present in this protein sequence?"
},
{
"from": "gpt",
"value": "Based on the sequence, this protein contains:\n1. HTH rrf2-type at residues 2-129. This entry represents transcriptional regulators such as Desulfovibrio ... |
A0QBY3_struct_transmembrane_region_483 | A0QBY3 | Unknown | ALGLAMAFGRFLPIVLVLALA | [
{
"from": "human",
"value": "<protein_sequence>\nWhat can you identify about this sequence region?"
},
{
"from": "gpt",
"value": "Based on the sequence, this is a Transmembrane helix at residues 483-503."
}
] |
Q8Z4X8_struct_transmembrane_region_9 | Q8Z4X8 | Unknown | MLLLSLPALIIGVASSLVLIASM | [
{
"from": "human",
"value": "<protein_sequence>\nWhat type of structural element does this sequence represent?"
},
{
"from": "gpt",
"value": "Based on the sequence, this is a Transmembrane helix at residues 9-31."
}
] |
A9MLJ4_struct_transmembrane_region_289 | A9MLJ4 | Unknown | VVGLVIPTGYSFNLDGTSIYL | [
{
"from": "human",
"value": "<protein_sequence>\nWhat type of structural element does this sequence represent?"
},
{
"from": "gpt",
"value": "Based on the sequence, this is a Transmembrane helix at residues 289-309."
}
] |
Q8EFW5_fullseq_domains | Q8EFW5 | Unknown | MINHFSVLGIKPSAKEDDIKKAYRRLSNKYHPDKLLGASDEEKEQASQQLERVKKAYEVLSDPKLRNAFIRDFNNVIVTDPNSAMRELWDQFYP | [
{
"from": "human",
"value": "<protein_sequence>\nWhat domains can be recognized from this protein sequence?"
},
{
"from": "gpt",
"value": "Based on the sequence, this protein contains:\n1. J at residues 3-93"
}
] |
P76249_struct_transmembrane_region_188 | P76249 | Unknown | LAKVGNSLIGLMFVGFAARLA | [
{
"from": "human",
"value": "<protein_sequence>\nWhat type of structural element does this sequence represent?"
},
{
"from": "gpt",
"value": "Based on the sequence, this is a Transmembrane helix at residues 188-208."
}
] |
Q93PD4_struct_transmembrane_region_11 | Q93PD4 | Unknown | VVLVTVAQLVLKWGMMNIPLL | [
{
"from": "human",
"value": "<protein_sequence>\nWhat type of structural element does this sequence represent?"
},
{
"from": "gpt",
"value": "Based on the sequence, this is a Transmembrane helix at residues 11-31."
}
] |
A4WE68_struct_transmembrane_region_68 | A4WE68 | Unknown | LLALVTWGGVAFLLWYGFGAL | [
{
"from": "human",
"value": "<protein_sequence>\nWhat type of structural element does this sequence represent?"
},
{
"from": "gpt",
"value": "Based on the sequence, this is a Transmembrane helix at residues 68-88."
}
] |
A3PMX6_fullseq_domains | A3PMX6 | Unknown | MERTIDPGTLPYRPCVGIVLINREGLIFAGQRIDSPVPAWQMPQGGIDEGEKPREAALRELWEETGIPAERVEFVAKAPDWVTYDLPPELLGRVWGGKYRGQRQKWFLYRYLGTDDEVGIGTDHAEFSCWRWIGAEEMVAAIVPFKRAVYEEVVATFRPHLA | [
{
"from": "human",
"value": "<protein_sequence>\nWhat domains can be recognized from this protein sequence?"
},
{
"from": "gpt",
"value": "Based on the sequence, this protein contains:\n1. Nudix hydrolase at residues 11-155. Recently, the generic name 'NUDIX hydrolases' (NUcleoside DIphosphate l... |
Q0TI84_fullseq_allfeats | Q0TI84 | Unknown | MTLTASSSSRAVTNSPVVVALDYHNRDAAMAFVDKIDPRDCRLKVGKEMFTLFGPQFVSELQQRGFDIFLDLKFHDIPNTAAHAVAAAADLGVWMVNVHASGGARMMAAAREALVPFGKDAPLLIAVTVLTSMEASDLADLGVTLSPADYAERLAALTQKCGLDGVVCSAQEAVRFKQVFGQEFKLVTPGIRPQGSDAGDQRRIMTPEQALAAGVDYMVIGRPVTQSVDPAQTLKAINASLQRSA | [
{
"from": "human",
"value": "<protein_sequence>\nWhat sequence-derivable features are present in this protein?"
},
{
"from": "gpt",
"value": "Based on the sequence, this protein contains:\n 1. Proton donor at position 73 (active site)\n 2. substrate/cofactor: 8 binding site residues at positio... |
P0A2F4_fullseq_allfeats | P0A2F4 | Unknown | MSFELPALPYAKDALAPHISAETLEYHYGKHHQTYVTNLNNLIKGTAFEGKSLEEIVRTSEGGIFNNAAQVWNHTFYWNCLAPNAGGEPTGKLADAIAASFGSFAEFKAQFTDAAIKNFGSGWTWLVKSADGKLAIVSTSNAGTPLTTDATPLLTVDVWEHAYYIDYRNARPNYLEHFWALVNWEFVAKNLAA | [
{
"from": "human",
"value": "<protein_sequence>\nWhat functional and structural features can be identified in this sequence?"
},
{
"from": "gpt",
"value": "Based on the sequence, this protein contains:\n 1. substrate/cofactor at positions 27, 74, 157, 161 (4 binding site residues)"
}
] |
Q7CR87_struct_signal_peptide_1 | Q7CR87 | Unknown | MKNWKTLLLGIAMIANTSFA | [
{
"from": "human",
"value": "<protein_sequence>\nWhat structural feature is this sequence?"
},
{
"from": "gpt",
"value": "Based on the sequence, this is a Signal peptide at residues 1-20."
}
] |
P39381_struct_transmembrane_region_362 | P39381 | Unknown | LASATLCGAAALFIAALISTV | [
{
"from": "human",
"value": "<protein_sequence>\nWhat type of structural element does this sequence represent?"
},
{
"from": "gpt",
"value": "Based on the sequence, this is a Transmembrane helix at residues 362-382."
}
] |
Q1C6Z1_struct_transmembrane_region_34 | Q1C6Z1 | Unknown | GLMIMAGLFGFGGAFVSLLMS | [
{
"from": "human",
"value": "<protein_sequence>\nWhat type of structural element does this sequence represent?"
},
{
"from": "gpt",
"value": "Based on the sequence, this is a Transmembrane helix at residues 34-54."
}
] |
B7NF23_struct_transmembrane_region_458 | B7NF23 | Unknown | LSAQDPYYILPILMGVTMFFI | [
{
"from": "human",
"value": "<protein_sequence>\nWhat type of structural element does this sequence represent?"
},
{
"from": "gpt",
"value": "Based on the sequence, this is a Transmembrane helix at residues 458-478."
}
] |
Q0TIB5_struct_transmembrane_region_225 | Q0TIB5 | Unknown | TLSNLISAVLLIYLFRLYMLI | [
{
"from": "human",
"value": "<protein_sequence>\nWhat type of structural element does this sequence represent?"
},
{
"from": "gpt",
"value": "Based on the sequence, this is a Transmembrane helix at residues 225-245."
}
] |
A5IJD4_fullseq_domains | A5IJD4 | Unknown | MRFYIKTFGCQMNENDSETMAGLLMKEGFTPASAPEEADVVIINTCAVRRKSEEKAYSELGQMLKIKRKRKLVVGVAGCVAEKEREKLLERGADFVLGTRAVLKVTEAVKRALQGEKVALFEDHLDEYTHELPRIRSSKHHAWVTIIFGCDRFCTYCIVPYTRGREKSRPMEDILEEVRELAKQGYREVTFLGQNVDAYGKDLKDGSSLAKLLEEASKIEGIERIWFLTSYPTDFSDELIEVIARNPKVAKSVHLPVQSGSNRILKLMNRSYTKEEYLALLERIRSKVPDVAISSDIIVGFPTETEEDFMETIDLVEKAQ... | [
{
"from": "human",
"value": "<protein_sequence>\nWhat functional domains are present in this protein sequence?"
},
{
"from": "gpt",
"value": "Based on the sequence, this protein contains:\n1. MTTase N-terminal at residues 1-114. The methylthiotransferase (MTTase) or miaB-like family is named aft... |
B5YXD4_struct_region_of_interest_230 | B5YXD4 | Unknown | LQLSRLERVYQSEQAEKLLLA | [
{
"from": "human",
"value": "<protein_sequence>\nWhat can you identify about this sequence region?"
},
{
"from": "gpt",
"value": "Based on the sequence, this is a Linker at residues 230-250."
}
] |
A1AGN6_struct_transmembrane_region_207 | A1AGN6 | Unknown | FIAASGVREVFTAATLLLVLG | [
{
"from": "human",
"value": "<protein_sequence>\nWhat type of structural element does this sequence represent?"
},
{
"from": "gpt",
"value": "Based on the sequence, this is a Transmembrane helix at residues 207-227."
}
] |
Q0HTE5_fullseq_domains | Q0HTE5 | Unknown | MISIDSTAMKTNNFDLANLSQNDTALEIRNLDLRYGDKQALFNVSMKIPKKQVTAFIGPSGCGKSTLLRCINRMNDLVDNCHIDGEILLHGQNIYDKKIDVAALRRNVGMVFQRPNPFPKSIYENVVYGLRLQGINNRRELDEAAERSLRGAAIWDEVKDRLHDNAFGLSGGQQQRLVIARAIAIEPEVLLLDEPTSALDPISTLTIEELITELKTKYTVVIVTHNMQQAARVSDQTAFMYMGELVEYADTNTIFTTPKKRKTEDYITGRYG | [
{
"from": "human",
"value": "<protein_sequence>\nWhat domains can be recognized from this protein sequence?"
},
{
"from": "gpt",
"value": "Based on the sequence, this protein contains:\n1. ABC transporter at residues 26-267. This entry represents a conserved region found in a group of related AT... |
B7LXA7_struct_signal_peptide_1 | B7LXA7 | Unknown | MKLRWFAFLIVLLAG | [
{
"from": "human",
"value": "<protein_sequence>\nWhat structural feature is this sequence?"
},
{
"from": "gpt",
"value": "Based on the sequence, this is a Signal peptide at residues 1-15."
}
] |
B8G2S8_domain_4_79 | B8G2S8 | Unknown | PEMEERLRKIIVDQLGVDEAQVVPSASFTKDLNADSLDLVELIMSIEEEFGVEIPDEDAEKIQTVADALQYLETHQ | [
{
"from": "human",
"value": "<protein_sequence>\nWhat type of protein domain does this sequence encode?"
},
{
"from": "gpt",
"value": "Based on the sequence, this is a Carrier at residues 4-79. There are two types of fatty acid synthase systems. The type I system is found in metazoans and is car... |
B8H414_fullseq_allfeats | B8H414 | Unknown | MPRTHKIEDYRNFGIMAHIDAGKTTTTERILYYTGKSHKIGEVHDGAATMDWMEQEQERGITITSAATTAFWNDKRLNIIDTPGHVDFTIEVERSLRVLDGAVTVLDGNAGVEPQTETVWRQADKYKVPRIVFVNKMDKIGADFDKSVESIRDRLGAKAVPIQFPIGSESNLKGLVDLVRMKAVVWDNDGLGASYRDEEIPADLMDKAVEARAYLVENAVELDDDAMEAYLGGEEPSIETIKKCIRKAVLTGAFYPILCGSAFKNKGVQPLLDAVVDYLPSPVDIPPTKGIDFKTEEETTRKASDEEPLSVLAFKIMDDP... | [
{
"from": "human",
"value": "<protein_sequence>\nWhat sequence-derivable features are present in this protein?"
},
{
"from": "gpt",
"value": "Based on the sequence, this protein contains:\n 1. tr-type G at residues 8-283. The P-loop guanosine triphosphatases (GTPases) control a multitude of bio... |
Q12KC4_fullseq_allfeats | Q12KC4 | Unknown | MKIYLVGGAVRDALLGLTIKDKDYLVVGSTPAEMLSLGYRQVGKDFPVFLHPKNQQEYALARIERKTGTGYDGFSCDANEHVSLEEDLLRRDLTINAIAQDEQGQLHDPYGGQQDIIHKQLRHVSQAFVEDPLRVLRVARFAARFHSLGFTVATETMALMSQISLSGELEHLTAERVWQECERALATDEPQVFFEVLAQCGALEVLFPEIHALFGVPQPEKWHPEIDTGKHTLLSLKQASLLTDDMAIRFATLVHDLGKALSPKESLPKHHGHGQKGLPLIKQFCQRLRVPNDYRDLALLVSDQHQNIHNAFELKASTLV... | [
{
"from": "human",
"value": "<protein_sequence>\nWhat sequence-derivable features are present in this protein?"
},
{
"from": "gpt",
"value": "Based on the sequence, this protein contains:\n 1. HD at residues 228-329. The HD domain is found in a superfamily of enzymes with a predicted or known p... |
P43961_struct_signal_peptide_1 | P43961 | Unknown | MKKIILTLSLGLLTA | [
{
"from": "human",
"value": "<protein_sequence>\nWhat structural feature is this sequence?"
},
{
"from": "gpt",
"value": "Based on the sequence, this is a Signal peptide at residues 1-15."
}
] |
A5CU80_fullseq_allfeats | A5CU80 | Unknown | MLIAQRPTLTEESISEFRSRFVIEPLEPGFGYTLGNSLRRTLLSSIPGAAVTSIRIDGVLHEFSTVPGVKEDVTEIILNIKGLVVSSEHDEPITAYLRKQGAGQVTAADISAPAGVEIHNPELVIATLNEKAKFELELTIERGRGYVSATQNRSEFSEAGQIPVDSIYSPVLKVTYRVEATRAGERTDFDRLVVDVETKSAITPRDAIASAGRTLTELFGLARELNSAAEGIEIGPAPVDAVLSSELSMPIEDLDLSVRSYNCLKREGINNVSELVALSETQLMNIRNFGQKSVDEVKDKLVELGLSLKDAVPGFDGAHY... | [
{
"from": "human",
"value": "<protein_sequence>\nWhat sequence-derivable features are present in this protein?"
},
{
"from": "gpt",
"value": "Based on the sequence, this protein contains:\n 1. Alpha N-terminal domain (alpha-NTD) at residues 1-226\n 2. Alpha C-terminal domain (alpha-CTD) at res... |
Q7MXN7_fullseq_allfeats | Q7MXN7 | Unknown | MMRVKAKKALGQHFLRDLSIAERIADTLSEHKALPVLEIGPGMGVLTQFLLRKGHDVRVIEIDGESVSYLREEFPELSDRIIEGDFLHYPLSELFPGGRQYCLIGNYPYNISSQIFFRLLDVREQIPCCSGMLQREVAMRLASPPGKKDYGILSVLLQLWYNIEYLFTVDASVFDPPPKVQSGVIRLTRNDRKELPCSEKALKTVVKTAFGQRRKTLRNSLRGILPAGFDRFDEPVFSKRPEQLSPDDFIALTLLLQQ | [
{
"from": "human",
"value": "<protein_sequence>\nWhat functional and structural features can be identified in this sequence?"
},
{
"from": "gpt",
"value": "Based on the sequence, this protein contains:\n 1. substrate/cofactor: 6 binding site residues at positions 13, 15, 40, ... 106"
}
] |
B7L849_struct_transmembrane_region_420 | B7L849 | Unknown | LGGCFPLLIQMPIFLALYYML | [
{
"from": "human",
"value": "<protein_sequence>\nWhat type of structural element does this sequence represent?"
},
{
"from": "gpt",
"value": "Based on the sequence, this is a Transmembrane helix at residues 420-440."
}
] |
A5VYG2_struct_signal_peptide_1 | A5VYG2 | Unknown | MFLRHCITFTMIALLAG | [
{
"from": "human",
"value": "<protein_sequence>\nWhat structural feature is this sequence?"
},
{
"from": "gpt",
"value": "Based on the sequence, this is a Signal peptide at residues 1-17."
}
] |
P94680_domain_230_317 | P94680 | Unknown | QPFELVLQRAGLSTTVDAHESVLDAMERVGVDFPWSCREGICGTCEAPVLEGEVQHLDYVLSPEERAEQRRMMVCVSRCGGGRLVLDI | [
{
"from": "human",
"value": "<protein_sequence>\nIdentify the functional domain in this amino acid sequence."
},
{
"from": "gpt",
"value": "Based on the sequence, this is a 2Fe-2S ferredoxin-type at residues 230-317. Ferredoxins are small, acidic, electron transfer proteins that are ubiquitous i... |
Q9ZDZ2_struct_region_of_interest_63 | Q9ZDZ2 | Unknown | HRKEREGRNPKTGAKMKIDA | [
{
"from": "human",
"value": "<protein_sequence>\nWhat can you identify about this sequence region?"
},
{
"from": "gpt",
"value": "Based on the sequence, this is a Disordered at residues 63-82."
}
] |
P52143_struct_signal_peptide_1 | P52143 | Unknown | MNRTSPYYCRRSVLSLLISALIYAPPGMA | [
{
"from": "human",
"value": "<protein_sequence>\nWhat structural feature is this sequence?"
},
{
"from": "gpt",
"value": "Based on the sequence, this is a Signal peptide at residues 1-29."
}
] |
P42306_struct_transmembrane_region_149 | P42306 | Unknown | FGLGYIGSTIPFIISIAVILL | [
{
"from": "human",
"value": "<protein_sequence>\nWhat structural feature is this sequence?"
},
{
"from": "gpt",
"value": "Based on the sequence, this is a Transmembrane helix at residues 149-169."
}
] |
Q050C7_struct_transmembrane_region_156 | Q050C7 | Unknown | VGFRDAILIGIFQCVALIPGV | [
{
"from": "human",
"value": "<protein_sequence>\nWhat structural feature is this sequence?"
},
{
"from": "gpt",
"value": "Based on the sequence, this is a Transmembrane helix at residues 156-176."
}
] |
B9L173_struct_transmembrane_region_76 | B9L173 | Unknown | LVFLVAPLLSFALAPLGAAVI | [
{
"from": "human",
"value": "<protein_sequence>\nWhat type of structural element does this sequence represent?"
},
{
"from": "gpt",
"value": "Based on the sequence, this is a Transmembrane helix at residues 76-96."
}
] |
B0CKF4_struct_transmembrane_region_53 | B0CKF4 | Unknown | PVLAVISILCIAVGAGASGAL | [
{
"from": "human",
"value": "<protein_sequence>\nWhat type of structural element does this sequence represent?"
},
{
"from": "gpt",
"value": "Based on the sequence, this is a Transmembrane helix at residues 53-73."
}
] |
Q728U5_struct_transmembrane_region_96 | Q728U5 | Unknown | YIWLTLLVFTGFGFIGFLDDY | [
{
"from": "human",
"value": "<protein_sequence>\nWhat type of structural element does this sequence represent?"
},
{
"from": "gpt",
"value": "Based on the sequence, this is a Transmembrane helix at residues 96-116."
}
] |
B1YIW5_struct_transmembrane_region_37 | B1YIW5 | Unknown | LITVFAGYVVAASYLTDDVLL | [
{
"from": "human",
"value": "<protein_sequence>\nWhat type of structural element does this sequence represent?"
},
{
"from": "gpt",
"value": "Based on the sequence, this is a Transmembrane helix at residues 37-57."
}
] |
P72021_fullseq_allfeats | P72021 | Unknown | MAEFPFEISPMFEGERVRKEGMFVELGGPKSLGLELVRAADMDAIEDDKVTIVGPDLKDMEEGKTYPWAMIFNIGGELVEPDLESVVERRVHDFINYCQGIMHLNQRYDVWMRVSKDTAGKMDSFEPFGKAVMMLFKTELPFIEKMQVTFYTGKEEVEKQMELAKEIFKARDARTKDLHDEDVDVFYGCTLCQSFAPTNVCVVSPDRISLCGAINWFDGRAAAKVDPEGPQFEIAKGDLLDAVTGEYTGVNEIAKKLSSGEFDKIKLHSFFDSPHTSCGCFEVVGFYIPEVDGIGWVDREYQGMAPNGIGFSTMAGQTGG... | [
{
"from": "human",
"value": "<protein_sequence>\nWhat functional and structural features can be identified in this sequence?"
},
{
"from": "gpt",
"value": "Based on the sequence, this protein contains:\n 1. substrate/cofactor at positions 189, 192, 278, 280 (4 binding site residues)"
}
] |
End of preview. Expand in Data Studio
IDPRO-QA — Multi-stage protein-function QA corpus
Instruction-tuning corpus used to train the IDPro (Illuminating the Dark PROteome) model. Generated from UniProt + InterPro + M-CSA + Prosite annotations over bacterial proteins, organised into four progressively harder curricula (stages 1 → 4).
Stages
| Stage | Records | Description |
|---|---|---|
| stage1 | 669,698 | Single-feature QA: one domain / binding site / region per record. |
| stage2 | 30,552 | Multi-feature, multi-turn QA combining several annotations per protein. |
| stage3 | 24,277 | Full-sequence multi-turn reasoning across all features of a protein. |
| stage4 | 209,779 | Chain-of-thought QA with explicit IDENTIFY / LOCATE / RELATE / INFER / CONTEXTUALIZE structure. |
All records share the same schema:
{
"long_format_id": "<uniprot_acc>_<stage>_<variant>",
"id": "<uniprot_acc>",
"protein": "<name or 'Unknown'>",
"amino_seq": "<full protein sequence>",
"conversations": [
{"from": "human", "value": "<protein_sequence>\n<question>"},
{"from": "gpt", "value": "<answer>"}
]
}
The <protein_sequence> token in the human turn is a placeholder consumed by
the IDPro trainer; replace or strip it as needed for other consumers.
Loading
from datasets import load_dataset
stage1 = load_dataset("tumorailab/IDPRO-QA", name="stage1", split="train")
stage4 = load_dataset("tumorailab/IDPRO-QA", name="stage4", split="train")
Or stream the full corpus across all stages:
ds = load_dataset(
"tumorailab/IDPRO-QA",
data_files={"train": "stage*/stage*_qa.jsonl"},
split="train",
streaming=True,
)
Source
Built by preliminary_data/training_data/scripts/generate_qa.py in the IDPro
source tree. See the IDPro project README for the upstream pipeline.
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