Datasets:
json dict | jpg imagewidth (px) 49 4.1k | __key__ stringlengths 6 6 | __url__ stringclasses 29
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{
"caption": "Rescuing Molecular Oscillations within the LNvs Is Not Sufficient to Rescue Locomotor Activity RhythmsThe rescued mutant genotype is y w;pdf–GAL4;UAS–CYC,cyc01/cyc01. The flies were entrained in standard LD conditions and timepoints taken. Molecular oscillations were examined by whole-mount in situ hybr... | 000000 | hf://datasets/vector-institute/open-pmc-18m@55d965cbdff6a9fc02c8057fafee9db0ce600386/data_00000.tar | |
{
"caption": "All Brain Clock Neuronal Groups Maintain Robust Oscillations of tim RNA Levels in DDWild-type flies were entrained for at least 3 days and then released into DD. tim RNA was assayed at trough (left panels) and peak (right panels) timepoints by whole-mount in situ hybridization. Wild-type flies in LD (A)... | 000001 | hf://datasets/vector-institute/open-pmc-18m@55d965cbdff6a9fc02c8057fafee9db0ce600386/data_00000.tar | |
{
"caption": "A PDF Peptide Binds to Many Cells, Including Several Clock Neuronal GroupsIn vitro biontinylated PDF peptide was used to visualize the peptide binding locations (middle panels, with Cy3) in the brain (see Materials and Methods for details). We used membrane-bound GFP (green panels on the left) to label ... | 000002 | hf://datasets/vector-institute/open-pmc-18m@55d965cbdff6a9fc02c8057fafee9db0ce600386/data_00000.tar | |
{
"caption": "Electron micrograph of Proteobacteria in eukaryotic cell",
"domain": "Medical",
"primary_modality": "Microscopy",
"secondary_modality": "Electron microscopy",
"source_license": "other",
"subfigure_path": "/datasets/PMC-15M/filtered_biomedica/filtered_v4/subfigures_final/subfig_0_filelist_comme... | 000003 | hf://datasets/vector-institute/open-pmc-18m@55d965cbdff6a9fc02c8057fafee9db0ce600386/data_00000.tar | |
{
"caption": "A. Real time image of the translocation of ARF1-GFP to the plasma membrane. HeLa cells that had been stably transfected with ARF1-GFP were transiently transfected with myc-ARNO, serum starved overnight, and treated with 100 nM insulin. Images were collected every 30 seconds using a Molecular Dynamics 20... | 000004 | hf://datasets/vector-institute/open-pmc-18m@55d965cbdff6a9fc02c8057fafee9db0ce600386/data_00000.tar | |
{
"caption": "A Constellation of NeuronsImage courtesy of Miles Herkenham.",
"domain": "Medical",
"primary_modality": "Microscopy",
"secondary_modality": "Fluorescence microscopy",
"source_license": "other",
"subfigure_path": "/datasets/PMC-15M/filtered_biomedica/filtered_v4/subfigures_final/subfig_0_fileli... | 000005 | hf://datasets/vector-institute/open-pmc-18m@55d965cbdff6a9fc02c8057fafee9db0ce600386/data_00000.tar | |
{
"caption": "Expression of Dll in Bacteriocytes and the Pattern of Bacteriocyte Development Are Conserved in Parthenogenetic Females of P. spyrothecae\nConfocal micrographs of P. spyrothecae parthenogenetic embryos stained with anti-Dll antibody (red).(A) Dll is first detected in stage 6 embryos in one or two nuclei... | 000006 | hf://datasets/vector-institute/open-pmc-18m@55d965cbdff6a9fc02c8057fafee9db0ce600386/data_00000.tar | |
{
"caption": "Elimination of B. aphidicola by Treatment with Antibiotics Has No Effect on the Determination and Maintenance of the Bacteriocyte Cell Fate in A. pisum\n(A–C) Confocal micrographs of control embryos stained with anti-Dll antibody (red) show expression of Dll, as described in Figure 1. Enlarged views of ... | 000007 | hf://datasets/vector-institute/open-pmc-18m@55d965cbdff6a9fc02c8057fafee9db0ce600386/data_00000.tar | |
{
"caption": "The Second Wave of Bacteriocyte DeterminationIn (A)–(D), the embryos, which are normally folded in upon themselves in a pretzel shape within the ovariole (Miura et al. 2003), have been dissected flat, stained with anti-Dll antibody (red) and phalloidin (green), and examined with a confocal microscope.(A... | 000008 | hf://datasets/vector-institute/open-pmc-18m@55d965cbdff6a9fc02c8057fafee9db0ce600386/data_00000.tar | |
{
"caption": "Bacteriocytes Are Retained in One Species That Has Evolutionarily Lost Bacteria, but Not in Males of Another Species That Do Not Inherit Bacteria(A and B) Confocal micrographs of embryos of T. styraci stained with anti-Dll antibody (red). In T. styraci, in which B. aphidicola has been evolutionarily los... | 000009 | hf://datasets/vector-institute/open-pmc-18m@55d965cbdff6a9fc02c8057fafee9db0ce600386/data_00000.tar | |
{
"caption": "Expression of Three Transcription Factors during Early Bacteriocyte Development(A) Drawings of some stages of pea aphid embryonic development, approximately to scale. Embryos develop viviparously within a follicular epithelium of the ovariole (data not shown). For a complete description, see Miura et al... | 000010 | hf://datasets/vector-institute/open-pmc-18m@55d965cbdff6a9fc02c8057fafee9db0ce600386/data_00000.tar | |
{
"caption": "Caenorhabditis elegans worms",
"domain": "Medical",
"primary_modality": "Radiology",
"secondary_modality": "Magnetic Resonance",
"source_license": "other",
"subfigure_path": "/datasets/PMC-15M/filtered_biomedica/filtered_v4/subfigures_final/subfig_0_filelist_commercial_batch_0_0-PMC212701-0-pb... | 000011 | hf://datasets/vector-institute/open-pmc-18m@55d965cbdff6a9fc02c8057fafee9db0ce600386/data_00000.tar | |
{
"caption": "ARK and DRONC Are Required for Spermatid Individualization(A and C) Testis from β2tub-Ark-RNAi and β2tub-Dn-DRONC males, respectively. Active DRICE-positive cysts are present, but cystic bulges and waste bags are largely absent.(B and D) Investment cone movements in testis from β2tub-Ark-RNAi and β2tub-... | 000012 | hf://datasets/vector-institute/open-pmc-18m@55d965cbdff6a9fc02c8057fafee9db0ce600386/data_00000.tar | |
{
"caption": "The bln1 P-Element Insertion, Which Inhibits Cyt-c-d Expression, Results in Pleiotropic Defects in Spermatogenesis(A) Genomic organization of the cyt-c-d region. Upper half of the panel illustrates the structure of the region, as described by Arama et al. (2003). The lower half of the panel indicates th... | 000013 | hf://datasets/vector-institute/open-pmc-18m@55d965cbdff6a9fc02c8057fafee9db0ce600386/data_00000.tar | |
{
"caption": "HID, dFADD, and DREDD Participate in Individualization(A) HID protein (green) is concentrated in the region of the cystic bulge, which is marked by the presence of the phalloidin-stained individualization complex (red).(B) HID immunoreactivity is absent in testis from hid 05014/H99 flies.(C) Active DRON... | 000014 | hf://datasets/vector-institute/open-pmc-18m@55d965cbdff6a9fc02c8057fafee9db0ce600386/data_00000.tar | |
{
"caption": "DRONC Activation Occurs in Association with Individualization Complexes and Is ARK-Dependent(A and B) Wild-type testis stained for active DRICE (green), phalloidin-stained filamentous actin (red), and TOTO-3-stained DNA (blue). (A) Active DRICE is present throughout the length of cysts undergoing indivi... | 000015 | hf://datasets/vector-institute/open-pmc-18m@55d965cbdff6a9fc02c8057fafee9db0ce600386/data_00000.tar | |
{
"caption": "Active DRICE Is Eliminated from the Cytoplasm of Wild-Type Spermatids Following Passage of the Individualization Complex, but Not from Spermatids in Which Caspase Activity Has Been Inhibited(A) Cystic bulge from a wild-type cyst stained with active DRICE (red). The cystic bulge (arrowhead) is moving to ... | 000016 | hf://datasets/vector-institute/open-pmc-18m@55d965cbdff6a9fc02c8057fafee9db0ce600386/data_00000.tar | |
{
"caption": "driceless Males Lack Active Drice Staining and Show Defects in Individualization(A) Testis from driceless male stained with active DRICE. Active DRICE staining is eliminated.(B) Elongated cysts from driceless male. AXO49 staining (blue) outlines the location of three cystic bulges. Individualization com... | 000017 | hf://datasets/vector-institute/open-pmc-18m@55d965cbdff6a9fc02c8057fafee9db0ce600386/data_00000.tar | |
{
"caption": "Caspase Activity Is Required for Spermatid Individualization(A–C) Testis of different genotypes were visualized with antibodies specific for activated Drice (green). (A) Wild-type testis. Active DRICE is present in multiple elongated cysts. Cystic bulges (cb) and waste bags (wb) are indicated by arrows.... | 000018 | hf://datasets/vector-institute/open-pmc-18m@55d965cbdff6a9fc02c8057fafee9db0ce600386/data_00000.tar | |
{
"caption": "Developing spermatids in a normal Drosophila testis",
"domain": "Medical",
"primary_modality": "Microscopy",
"secondary_modality": "Fluorescence microscopy",
"source_license": "other",
"subfigure_path": "/datasets/PMC-15M/filtered_biomedica/filtered_v4/subfigures_final/subfig_0_filelist_commer... | 000019 | hf://datasets/vector-institute/open-pmc-18m@55d965cbdff6a9fc02c8057fafee9db0ce600386/data_00000.tar | |
{
"caption": "Histological Architecture of CSR Gene Expression in Breast CancerRepresentative ISH of LOXL2 and SDFR1 and IHC of PLOD2, PLAUR, and ESDN are shown (magnification, 200×). Panels for LOXL2, PLAUR, PLOD2, and ESDN represent cores of normal and invasive ductal breast carcinoma from different patients on the... | 000020 | hf://datasets/vector-institute/open-pmc-18m@55d965cbdff6a9fc02c8057fafee9db0ce600386/data_00000.tar | |
{
"caption": "Effect of deH on Agouti ExpressionComparable sections from at/at; deH/deH and at/at; +/+ littermates.(A) At E14.5, deH/deH embryos have a smaller body cavity and loose skin within which Agouti expression appears to be shifted dorsally, as marked by arrows (scale bars = 500 μm).(B) At P4.5, Agouti expres... | 000021 | hf://datasets/vector-institute/open-pmc-18m@55d965cbdff6a9fc02c8057fafee9db0ce600386/data_00000.tar | |
{
"caption": "Embryonic Establishment of Dorsoventral Skin PatterningPieces of skin from dorsal, flank, and ventral regions of at/a E12.5 embryos were transplanted into the testes of congenic animals as described in the text. Hair color of the grafts was examined 3 wk later. Grafts of ventral embryonic skin (n = 3) p... | 000022 | hf://datasets/vector-institute/open-pmc-18m@55d965cbdff6a9fc02c8057fafee9db0ce600386/data_00000.tar | |
{
"caption": "Developmental Expression of Tbx15\n(A) At E12.5, transverse sections at different levels show expression in head mesenchyme (a and b); myotome, occipital, and periocular mesenchyme (b); palatal shelf, cervical sclerotome, and nasal cartilage (c); maxillary and mandibular processes (d); limbs (e); and my... | 000023 | hf://datasets/vector-institute/open-pmc-18m@55d965cbdff6a9fc02c8057fafee9db0ce600386/data_00000.tar | |
{
"caption": "Embryonic Expression of Tbx15 Compared to Agouti in at/at Mice(A and C) Tbx15. (B and D) Agouti. At E12.5, expression of Tbx15 in dorsal skin is approximately complementary to that of Agouti in ventral skin. At E14.5, the levels of expression for both genes are lower, but Tbx15 expression has expanded v... | 000024 | hf://datasets/vector-institute/open-pmc-18m@55d965cbdff6a9fc02c8057fafee9db0ce600386/data_00000.tar | |
{
"caption": "Centrosome-independent spindle assembly",
"domain": null,
"primary_modality": null,
"secondary_modality": null,
"source_license": null,
"subfigure_path": "/datasets/PMC-15M/filtered_biomedica/filtered_v4/subfigures_final/subfig_0_filelist_commercial_batch_0_0-PMC314476-0-pbiop0020026pg001.jpg"... | 000025 | hf://datasets/vector-institute/open-pmc-18m@55d965cbdff6a9fc02c8057fafee9db0ce600386/data_00000.tar | |
{
"caption": "Centriole Migration in Primary Spermatocytes(A) Time-lapse series of confocal images from a wild-type primary spermatocyte expressing GFP-PACT (centrioles) and His2AvD–GFP (chromosomes). The centrioles (arrows) can be seen moving away from the plasma membrane (0) towards the nucleus (N) and then migrati... | 000026 | hf://datasets/vector-institute/open-pmc-18m@55d965cbdff6a9fc02c8057fafee9db0ce600386/data_00000.tar | |
{
"caption": "Time-Lapse Series of Meiosis Progression in Control, asp, and Colcemid-Treated SpermatocytesTimepoint 0 coincides with the time of NEB revealed by the sudden entry of GFP signal into the nucleus. In control cells (Video 2), microtubules are mainly organised around the centrosomes (arrows). However, when... | 000027 | hf://datasets/vector-institute/open-pmc-18m@55d965cbdff6a9fc02c8057fafee9db0ce600386/data_00000.tar | |
{
"caption": "Chromosome Segregation in Anastral Spindles in Drosophila Spermatocytes(Control [Video 5]) At metaphase I (0), the bivalents (revealed by a His2Avd–YFP fusion, shown by double arrowheads) are aligned in the middle of the spindle (revealed by a GFP–α-tubulin fusion), at the metaphase plate. At the onset ... | 000028 | hf://datasets/vector-institute/open-pmc-18m@55d965cbdff6a9fc02c8057fafee9db0ce600386/data_00000.tar | |
{
"caption": "The Place of Noncentrosomal Microtubule NucleationThe initial stages of noncentrosomal microtubule nucleation revealed by an endogenous GFP–α-tubulin fusion (left) and phase contrast (right). Following the corresponding videos, it is possible to unmistakably tell the chromosomes (arrows) apart form the ... | 000029 | hf://datasets/vector-institute/open-pmc-18m@55d965cbdff6a9fc02c8057fafee9db0ce600386/data_00000.tar | |
{
"caption": "SIRT-1 Deacetylase—the Human Enzyme That Promotes Cell Survival—in a Dividing Human CellThe enzyme is marked in red, and the image is superimposed on acetylated proteins (green) and condensed chromosomes (blue). (Image courtesy of David Sinclair.)",
"domain": "Medical",
"primary_modality": "Microsco... | 000030 | hf://datasets/vector-institute/open-pmc-18m@55d965cbdff6a9fc02c8057fafee9db0ce600386/data_00000.tar | |
{
"caption": "Expression of ArmΔArm Leads to the Nuclear Localization of Endogenous ArmProtein(A) Wild-type Arm protein appears in stripes that correspond to cells responding to Wg signaling.(B) Expression of ArmΔArm in an armF1a background leads to the nuclear localization of endogenous Arm.(C and D) Dark-field imag... | 000031 | hf://datasets/vector-institute/open-pmc-18m@55d965cbdff6a9fc02c8057fafee9db0ce600386/data_00000.tar | |
{
"caption": "C-Terminally Truncated Arm Can Signal If Its Levels Are Increased(A) armXM19 shows a wg mutant phenotype.(B) Expression of GAL4/UAS-driven ArmXM19 protein in armXM19 mutant background rescues this to a wild-type pattern.(C) The same is true of expression of an endogenous promoter-driven truncation ArmS8... | 000032 | hf://datasets/vector-institute/open-pmc-18m@55d965cbdff6a9fc02c8057fafee9db0ce600386/data_00000.tar | |
{
"caption": "ΔArm Functions through Endogenous Arm(A) Embryonic cuticle of armF1a mutant showing a weak loss-of-function phenotype.(B) Cuticle of armLM134 mutant embryo showing a strong loss-of-signaling phenotype.(C) Embryo mutant for armF1a expressing ArmΔArm showing relatively normal segment polarity.(D) armLM134... | 000033 | hf://datasets/vector-institute/open-pmc-18m@55d965cbdff6a9fc02c8057fafee9db0ce600386/data_00000.tar | |
{
"caption": "Relief of C-Terminal Repression through the Elimination of Cby Leads to Uniform Activation of Signaling(A) A wild-type cuticle shown for comparison.(B) Expression of ArmΔArm in the armF1a background.(C) Expression of a Cby RNAi construct along with ArmΔArm in the armF1a background.(D) Expression of a Cb... | 000034 | hf://datasets/vector-institute/open-pmc-18m@55d965cbdff6a9fc02c8057fafee9db0ce600386/data_00000.tar | |
{
"caption": "ArmΔArm Requires Endogenous ArmEndogenous allele indicated at top; ectopically expressed transgenes indicated at left.(A) The wild-type cuticle of a Drosophila embryo.(B) The armXM19 “weak” allele phenotype, similar to wg mutations in which the entire cuticle is covered with denticles.(C) The armO43A01 ... | 000035 | hf://datasets/vector-institute/open-pmc-18m@55d965cbdff6a9fc02c8057fafee9db0ce600386/data_00000.tar | |
{
"caption": "Tumor MorphologiesHemotoxylin and eosin staining of WAP-T121 (C and D) and WAP-T\n121\np53+/− (A and B) (also representative of WAP-T121) tumor sections shows that terminal stage adenocarcinomas have varied morphologies. Poorly differentiated solid tumors were comprised of nests (A) or cords of epitheli... | 000036 | hf://datasets/vector-institute/open-pmc-18m@55d965cbdff6a9fc02c8057fafee9db0ce600386/data_00000.tar | |
{
"caption": "Mammary-Specific Inactivation of the pRb Pathway Induces Extensive AbnormalitiesHistologic comparisons of nontransgenic (A–D), mosaic (F0 line 2 [E–H]), and transgenic (F1, line 3 [I–L]) lactating mammary glands reveals that T121 expression results in increased proliferation and apoptosis. Hemotoxylin a... | 000037 | hf://datasets/vector-institute/open-pmc-18m@55d965cbdff6a9fc02c8057fafee9db0ce600386/data_00000.tar | |
{
"caption": "EGF-CFC Coreceptor Depen-dence Determines Susceptibility to Antagonism by Lefty(A–L) Embryos were injected with 75 pg of SqtActβB[loopβ8] mRNA (A–C), 75 pg of SqtActβA[loopβ8] mRNA (D–F), 200 pg of Vg1ActβB[loopβ8] mRNA (G–I), or 200 pg ActSqt[Finger1-loopβ8] mRNA (J–L). Embryos were further double-inje... | 000038 | hf://datasets/vector-institute/open-pmc-18m@55d965cbdff6a9fc02c8057fafee9db0ce600386/data_00000.tar | |
{
"caption": "EGF-CFC Coreceptors Genetically Interact with LeftyLive wild-type zebrafish embryos at 30 h postfertilization (hpf).(A1, B1, and C1) Ventral views of the head.(A1′, B2, B3, and C1′) Lateral views, with anterior to the left, dorsal up.(A1, A1′, B1, B2, and B3) Wild-type embryos were injected with 20 pg o... | 000039 | hf://datasets/vector-institute/open-pmc-18m@55d965cbdff6a9fc02c8057fafee9db0ce600386/data_00000.tar | |
{
"caption": "Solid Tumor Growth Is Inhibited by Systemic RI-TATp53C′ Peptide Administration(A) Delivery of RI-TATp53C′-biotin to subcutaneous TA3/St tumors after IP administration to immune competent A/J mice.(B) Reduction of solid TA3/St tumor growth in immune competent mice as a result of systemic administration o... | 000040 | hf://datasets/vector-institute/open-pmc-18m@55d965cbdff6a9fc02c8057fafee9db0ce600386/data_00000.tar | |
{
"caption": "Decreased Fiber CoherenceDecreased fiber coherences, as observed with DTI, in persistent developmental stutterers compared with a fluent control group. A red dot indicates the peak difference in a coronal (top left), axial (top right), and a sagittal (bottom) slice.",
"domain": "Medical",
"primary_m... | 000041 | hf://datasets/vector-institute/open-pmc-18m@55d965cbdff6a9fc02c8057fafee9db0ce600386/data_00000.tar | |
{
"caption": "PhageNegative stain electron micrograph of the gamma phage from which the PlyG lytic enzyme was cloned for use to control B. anthracis. (Photograph courtesy of Vincent Fischetti and Raymond Schuch, The Rockefeller University.)",
"domain": null,
"primary_modality": null,
"secondary_modality": null,... | 000042 | hf://datasets/vector-institute/open-pmc-18m@55d965cbdff6a9fc02c8057fafee9db0ce600386/data_00000.tar | |
{
"caption": "Transgene expression is associated with increased cell proliferation and cell death (apoptosis)",
"domain": "Medical",
"primary_modality": "Microscopy",
"secondary_modality": "Fluorescence microscopy",
"source_license": "other",
"subfigure_path": "/datasets/PMC-15M/filtered_biomedica/filtered_... | 000043 | hf://datasets/vector-institute/open-pmc-18m@55d965cbdff6a9fc02c8057fafee9db0ce600386/data_00000.tar | |
{
"caption": "A Taste Bud in a MouseThis taste bud was taken from a transgenic mouse in which the marker green fluorescent protein is being driven by the T1R3 promoter; 20%–30% of the cells in the taste bud are expressing T1R3. (Photograph courtesy of Sami Damak, Mount Sinai School of Medicine, New York, New York, Un... | 000044 | hf://datasets/vector-institute/open-pmc-18m@55d965cbdff6a9fc02c8057fafee9db0ce600386/data_00000.tar | |
{
"caption": "Non-Taster or Supertaster?(A) Top surface of the tongue of a non-taster.(B) Tongue of a supertaster. The small circles are fungiform papillae, each of which contains about six taste buds.",
"domain": "Medical",
"primary_modality": "Microscopy",
"secondary_modality": "Light microscopy",
"source_l... | 000045 | hf://datasets/vector-institute/open-pmc-18m@55d965cbdff6a9fc02c8057fafee9db0ce600386/data_00000.tar | |
{
"caption": "Transmission electron micrograph of Wolbachia within an insect cell (Image courtesy of Scott O'Neill)",
"domain": null,
"primary_modality": null,
"secondary_modality": null,
"source_license": null,
"subfigure_path": "/datasets/PMC-15M/filtered_biomedica/filtered_v4/subfigures_final/subfig_0_fi... | 000046 | hf://datasets/vector-institute/open-pmc-18m@55d965cbdff6a9fc02c8057fafee9db0ce600386/data_00000.tar | |
{
"caption": "Localization of Puf ProteinsTAP-tagged Puf proteins were visualized in fixed cells. DNA was costained with 4′,6-diamidino-2-phenylindole dimethylsulfoxide (DAPI).",
"domain": "Medical",
"primary_modality": "Microscopy",
"secondary_modality": "Electron microscopy",
"source_license": "other",
"s... | 000047 | hf://datasets/vector-institute/open-pmc-18m@55d965cbdff6a9fc02c8057fafee9db0ce600386/data_00000.tar | |
{
"caption": "MRIs of a normal individual (bottom left) and a patient with microcephaly caused by an ASPM mutation (bottom right). Primate skulls provided courtesy of the Museum of Comparative Zoology, Harvard University",
"domain": "Medical",
"primary_modality": "Radiology",
"secondary_modality": "Magnetic Res... | 000048 | hf://datasets/vector-institute/open-pmc-18m@55d965cbdff6a9fc02c8057fafee9db0ce600386/data_00000.tar | |
{
"caption": "Time-Lapse Imaging of Astrocytes In VivoFour astrocytes, from which fluorometric Ca2+ imaging (0.5 Hz) was made, are outlined. A blood vessel, outlined by the astrocyte end feet, runs diagonally across the viewed area. White arrows show the end foot connected to the imaged astrocyte.",
"domain": "Medi... | 000049 | hf://datasets/vector-institute/open-pmc-18m@55d965cbdff6a9fc02c8057fafee9db0ce600386/data_00000.tar | |
{
"caption": "FMRI Signal in RH aSTG during Initial Solving Efforts(A) Voxels in right temporal lobe showing baseline-to-peak event-related FMRI signal when subjects first encounter problems, overlaid on the averaged normalized structural image of all subjects. The cluster is in RH aSTG, with a volume of 469 mm3, wit... | 000050 | hf://datasets/vector-institute/open-pmc-18m@55d965cbdff6a9fc02c8057fafee9db0ce600386/data_00000.tar | |
{
"caption": "FMRI Insight Effect in RH aSTG(A) Voxels showing greater FMRI signal for insight than noninsight solutions, overlaid on the averaged normalized structural image of all subjects. The active area has a volume of 531 mm3 (peak t = 4.89 at 44, −9, −9 in Talairach space).(B) and (C) Group average signal chan... | 000051 | hf://datasets/vector-institute/open-pmc-18m@55d965cbdff6a9fc02c8057fafee9db0ce600386/data_00000.tar | |
{
"caption": "CAP Mutant ClonesFollicle cells lacking CAP accumulate actin (red) in their apical region. Ena (blue in the bottom panel), also accumulates apically in the mutant cells (looks pink in the clone of cells due to overlap with F-actin in red). The mutant cell clones are identified by the absence of GFP (gre... | 000052 | hf://datasets/vector-institute/open-pmc-18m@55d965cbdff6a9fc02c8057fafee9db0ce600386/data_00000.tar | |
{
"caption": "Astrocyte in the cerebral cortex",
"domain": "Medical",
"primary_modality": "Microscopy",
"secondary_modality": "Fluorescence microscopy",
"source_license": "other",
"subfigure_path": "/datasets/PMC-15M/filtered_biomedica/filtered_v4/subfigures_final/subfig_0_filelist_commercial_batch_0_0-PMC3... | 000053 | hf://datasets/vector-institute/open-pmc-18m@55d965cbdff6a9fc02c8057fafee9db0ce600386/data_00000.tar | |
{
"caption": "The Blastula Dorsal Animal Cap Is Specified to Form CNS(A) Experimental diagram showing embryos injected with CerS mRNA from which three regions of the animal cap were dissected at blastula, cultured until stage 26, and processed for RT-PCR. The size of the explants was 0.3 mm by 0.3 mm in these samples... | 000054 | hf://datasets/vector-institute/open-pmc-18m@55d965cbdff6a9fc02c8057fafee9db0ce600386/data_00000.tar | |
{
"caption": "The BCNE Center Contributes to Forebrain and Midline Structures(A) Method used for lineage tracing of the BCNE center with biotin-dextran amine (BDA) labeled grafts.(B) Sagittal section of a recently grafted BCNE at stage 9.(C) Chd mRNA expression at stage 9.(D) BCNE descendants at stage 10.5.(E) Chd mR... | 000055 | hf://datasets/vector-institute/open-pmc-18m@55d965cbdff6a9fc02c8057fafee9db0ce600386/data_00000.tar | |
{
"caption": "Embryos with Defective Myocardial Function Do Not Form AV ECs(A–C) Fluorescence micrographs of embryos carrying a tie2::GFP transgene, visualized at 48 hpf. In (A), the endocardial ring is visible as a collection of GFP-positive cells at the AV boundary in wild-type (wt) embryos (red arrow). In (B), sih... | 000056 | hf://datasets/vector-institute/open-pmc-18m@55d965cbdff6a9fc02c8057fafee9db0ce600386/data_00000.tar | |
{
"caption": "Sequence and Expression Analysis of cfk\n(A) cfk encodes a sarcomeric actin highly homologous to zebrafish α-cardiac and α-skeletal actins. Cfk differs from zebrafish α-cardiac actin at six residues and from zebrafish α-skeletal actin at four residues, but from zebrafish β-actin at 28 residues. Residues... | 000057 | hf://datasets/vector-institute/open-pmc-18m@55d965cbdff6a9fc02c8057fafee9db0ce600386/data_00000.tar | |
{
"caption": "CDSC-Pax7 Cells Become Myogenic ProgenitorsMyf5 (A–C) and MyoD (D–F) protein (green) are expressed in proliferating CDSC-Pax7 cells. Exposure of CD45+:Sca1+ cultures to low mitogen medium induced the formation of multinucleated myotubes and expression of myogenic differentiation markers including MyHC (... | 000058 | hf://datasets/vector-institute/open-pmc-18m@55d965cbdff6a9fc02c8057fafee9db0ce600386/data_00000.tar | |
{
"caption": "CDSC-Pax7 Cells Efficiently Contribute to the Repair of Dystrophic Muscle(A) Wild-type muscle expressed dystrophin at the plasmalemma of all myofibers.(B) Dystrophin protein was not detected in muscle sections from dystrophin-deficient mdx:nude mice (mdx:nu).\n(C–F) CDSC-Pax7 cells differentiated in viv... | 000059 | hf://datasets/vector-institute/open-pmc-18m@55d965cbdff6a9fc02c8057fafee9db0ce600386/data_00000.tar | |
{
"caption": "Adenovirus-Pax7 Significantly Improves Regeneration In Vivo(A and B) Infection of ctx-damaged Pax7\n −/− muscles with Ad-Pax7 resulted in markedly improved muscle integrity and a significantly increased number of Desmin immunoreactive (green) regenerated fibers (B) relative to muscles treated with Ad-La... | 000060 | hf://datasets/vector-institute/open-pmc-18m@55d965cbdff6a9fc02c8057fafee9db0ce600386/data_00000.tar | |
{
"caption": "Pax7-infected stem cells rescue dystrophin expression",
"domain": "Medical",
"primary_modality": "Microscopy",
"secondary_modality": "Fluorescence microscopy",
"source_license": "other",
"subfigure_path": "/datasets/PMC-15M/filtered_biomedica/filtered_v4/subfigures_final/subfig_0_filelist_comm... | 000061 | hf://datasets/vector-institute/open-pmc-18m@55d965cbdff6a9fc02c8057fafee9db0ce600386/data_00000.tar | |
{
"caption": "tie2::GFP+ cells form the endocardial cushions",
"domain": "Medical",
"primary_modality": "Microscopy",
"secondary_modality": "Fluorescence microscopy",
"source_license": "other",
"subfigure_path": "/datasets/PMC-15M/filtered_biomedica/filtered_v4/subfigures_final/subfig_0_filelist_commercial_... | 000062 | hf://datasets/vector-institute/open-pmc-18m@55d965cbdff6a9fc02c8057fafee9db0ce600386/data_00000.tar | |
{
"caption": "Spindle Cell Tumors Resembling MPNSTs in Zebrafish Heterozygous for Mutations in RP Genes(A and B) Fish with apparent masses, as indicated by the arrows, or other evident pathology were selected for histological analysis: (A) a hi2582 fish, (B) a hi1034B fish.(C–H) Histopathology of representative tumor... | 000063 | hf://datasets/vector-institute/open-pmc-18m@55d965cbdff6a9fc02c8057fafee9db0ce600386/data_00000.tar | |
{
"caption": "Reversal Learning and the Orbitofrontal Cortex(A) Lateral and ventral views of the surface reconstructions of the lateral and medial orbitofrontal cortex lesions in monkeys (adapted from Iversen and Mishkin 1970), with the former monkeys having difficulty with the reversal task.(B) A ventral view of the... | 000064 | hf://datasets/vector-institute/open-pmc-18m@55d965cbdff6a9fc02c8057fafee9db0ce600386/data_00000.tar | |
{
"caption": "Zebrafish kugelig MutantsThe image shows live one-week-old zebrafish embryos. The embryos around the outside are wild-type fish. Those in the middle are a mutant called kugelig and have a homozygous mutation in a gene called cdx4. Loss of the proper functioning of this gene causes the obvious trunk and ... | 000065 | hf://datasets/vector-institute/open-pmc-18m@55d965cbdff6a9fc02c8057fafee9db0ce600386/data_00000.tar | |
{
"caption": "Zebrafish Hindbrain(Left) Dorsal view of GFP-expressing neurons in the hindbrain of a one-day-old zebrafish embryo. (Right) Antibody-labelled axons. (Image courtesy of Dave Lyons, University College London.)",
"domain": "Other",
"primary_modality": "Other",
"secondary_modality": "Other",
"source... | 000066 | hf://datasets/vector-institute/open-pmc-18m@55d965cbdff6a9fc02c8057fafee9db0ce600386/data_00000.tar | |
{
"caption": "A Zebrafish Pigment MutantThe mutant called bleached blond was produced by insertional mutagenesis. The embryos in the picture are four days old. At the top is a wild-type embryo, below is the mutant. The mutant lacks black pigment in the melanocytes because it fails to synthesise melanin properly. (Ima... | 000067 | hf://datasets/vector-institute/open-pmc-18m@55d965cbdff6a9fc02c8057fafee9db0ce600386/data_00000.tar | |
{
"caption": "Ras at the plasma membrane of S. cerevisiae",
"domain": null,
"primary_modality": null,
"secondary_modality": null,
"source_license": null,
"subfigure_path": "/datasets/PMC-15M/filtered_biomedica/filtered_v4/subfigures_final/subfig_0_filelist_commercial_batch_0_0-PMC406405-0-pbiop0020151pg001.... | 000068 | hf://datasets/vector-institute/open-pmc-18m@55d965cbdff6a9fc02c8057fafee9db0ce600386/data_00000.tar | |
{
"caption": "Different Activation Patterns in the Brains of Dyslexics As Compared to Normal Subjects in a Rhyming Task(Images courtesy of John Gabrieli, Stanford University.)",
"domain": "Medical",
"primary_modality": "Radiology",
"secondary_modality": "Magnetic Resonance",
"source_license": "other",
"subf... | 000069 | hf://datasets/vector-institute/open-pmc-18m@55d965cbdff6a9fc02c8057fafee9db0ce600386/data_00000.tar | |
{
"caption": "In Vivo Two-Photon Imaging Through the Thinned SkullYellow cameleon 3.12 at different depths (MTH-YC3.12-8) (A) and with high resolution (MTH-YC3.12-7) (B). (C) IP at different depths (MTH-IP-1).",
"domain": "Medical",
"primary_modality": "Microscopy",
"secondary_modality": "Electron microscopy",
... | 000070 | hf://datasets/vector-institute/open-pmc-18m@55d965cbdff6a9fc02c8057fafee9db0ce600386/data_00000.tar | |
{
"caption": "Doxycycline and tTA-Dependent FCIP ExpressionImmunohistochemical assay (A–F) using rabbit polyclonal GFP antibodies/peroxidase-DAB system: (A) YC3.12, single-positive (MTH-YC3.12-7), double-positive (MTH-YC3.12-7, αCamKII-tTA), and Dox-treated double-positive (MTH-YC3.12-7, αCamKII-tTA).(B) Cg2, single-... | 000071 | hf://datasets/vector-institute/open-pmc-18m@55d965cbdff6a9fc02c8057fafee9db0ce600386/data_00000.tar | |
{
"caption": "Light-Evoked Ca2+ Responses in Retinal Ganglion Cells(A) Intact, light-sensitive retinal whole mount with Sulforhodamine 101 (red) in the extracellular space. Blood vessels are red; IP-positive (MTH-IP-12) retinal ganglion cells are green; and unstained ganglion cells are dark. (Scale bar: 50 μm).(B) Pr... | 000072 | hf://datasets/vector-institute/open-pmc-18m@55d965cbdff6a9fc02c8057fafee9db0ce600386/data_00000.tar | |
{
"caption": "In Vivo Imaging of Odor-Evoked Ca2+ Signals with Transgenic Indicators in the Olfactory Bulb(A–C) IP (MTH-IP-12). (A) Raw fluorescence image. (B) Time course of fluorescence signal in the corresponding regions outlined in (C) (matching line colors). The black trace shows respiratory activity. (C) Color-... | 000073 | hf://datasets/vector-institute/open-pmc-18m@55d965cbdff6a9fc02c8057fafee9db0ce600386/data_00000.tar | |
{
"caption": "In Situ Protein Localization(A) IF studies of glomerular protein expression in Actn4\n+/+, Actn4K228E/+ , and Actn4\nK228E/K228E mice. As indicated, expression of α-actinin-4, ZO-1, and nephrin is shown, as is a merged image of α-actinin-4 and ZO-1 expression.(B) Glomerular expression of α-actinin-4 in ... | 000074 | hf://datasets/vector-institute/open-pmc-18m@55d965cbdff6a9fc02c8057fafee9db0ce600386/data_00000.tar | |
{
"caption": "In Vivo PhenotypeElectron micrographs from Actn4 wild-type (A) and Actn4\nK228E/K228E mice (B–D). As shown, Actn4\nK228E/K228E mice were found to have abnormalities that were typically focal, with some areas of podocyte foot process effacement (B), as well as areas that appeared essentially normal (C). ... | 000075 | hf://datasets/vector-institute/open-pmc-18m@55d965cbdff6a9fc02c8057fafee9db0ce600386/data_00000.tar | |
{
"caption": "Mutant α-Actinin-4 Behavior in Cells(A) Mutant and wild-type α-actinin-4 show different localization and dynamics when expressed in a conditionally immortalized differentiated mouse podocyte cell line. Differentiated podocytes were injected in the nucleus with equal concentrations of expression plasmid ... | 000076 | hf://datasets/vector-institute/open-pmc-18m@55d965cbdff6a9fc02c8057fafee9db0ce600386/data_00000.tar | |
{
"caption": "Mean Component Cluster Equivalent Dipole LocationsThe mean scalp map for each of the nine component clusters could be well fit by a single equivalent dipole (mean residual variance: 4.8%). The figure shows the locations and orientations of these dipoles, as determined by BESA, plotted on the spherical h... | 000077 | hf://datasets/vector-institute/open-pmc-18m@55d965cbdff6a9fc02c8057fafee9db0ce600386/data_00000.tar | |
{
"caption": "Four Different Species of Volvocales Algae(A) Gonium pectorale, (B) Eudorina elegans, (C) Pleodorina californica, and (D) Volvox carteri. These are unicellular organisms that live in colonies and have both large and small gametes. Photo courtesy of Aurora M. Nedelcu, from the Volvocales Information Proj... | 000078 | hf://datasets/vector-institute/open-pmc-18m@55d965cbdff6a9fc02c8057fafee9db0ce600386/data_00000.tar | |
{
"caption": "Scars of Sex(A) Streaks of sperm (St) received after a mating interaction in the hermaphroditic flatworm, Pseudobiceros bedfordi. (B) Received sperm appears to “burn” holes (H) in the receiver. Some (unknown) component of the ejaculate dissolves the skin tissue. Sc, scar tissue. (C) Exceptional case whe... | 000079 | hf://datasets/vector-institute/open-pmc-18m@55d965cbdff6a9fc02c8057fafee9db0ce600386/data_00000.tar | |
{
"caption": "Zooming in on mitochondria (Image by Peter Seibel, design by Shayna Roosevelt)",
"domain": null,
"primary_modality": null,
"secondary_modality": null,
"source_license": null,
"subfigure_path": "/datasets/PMC-15M/filtered_biomedica/filtered_v4/subfigures_final/subfig_0_filelist_commercial_batch... | 000080 | hf://datasets/vector-institute/open-pmc-18m@55d965cbdff6a9fc02c8057fafee9db0ce600386/data_00000.tar | |
{
"caption": "Mutant α-actinin-4 is mislocalizes and aggregates in renal glomeruli",
"domain": "Medical",
"primary_modality": "Microscopy",
"secondary_modality": "Fluorescence microscopy",
"source_license": "other",
"subfigure_path": "/datasets/PMC-15M/filtered_biomedica/filtered_v4/subfigures_final/subfig_... | 000081 | hf://datasets/vector-institute/open-pmc-18m@55d965cbdff6a9fc02c8057fafee9db0ce600386/data_00000.tar | |
{
"caption": "A Cell Culture Screen Identifies Novel Regulators of the Innate Immune Response(A) LPS induces an increase of about 10-fold in the number of Dipt-lacZ cells that stain positively for β-galactosidase. Ecdysone sensitizes the cells and promotes the response.(B) Dipt-lacZ induction by LPS requires known Im... | 000082 | hf://datasets/vector-institute/open-pmc-18m@55d965cbdff6a9fc02c8057fafee9db0ce600386/data_00000.tar | |
{
"caption": "A GFP-Relish Reporter Cell Line Subdivides DDRi dsRNA into Three Categories(A–B) Immunofluorescence of GFP-Relish cells with GFP-Relish in green, DNA in blue, and actin in red. Relish is predominantly cytoplasmic in untreated control cells and rapidly translocates to the nucleus of cells incubated with ... | 000083 | hf://datasets/vector-institute/open-pmc-18m@55d965cbdff6a9fc02c8057fafee9db0ce600386/data_00000.tar | |
{
"caption": "Malaria infecting red blood cells",
"domain": null,
"primary_modality": null,
"secondary_modality": null,
"source_license": null,
"subfigure_path": "/datasets/PMC-15M/filtered_biomedica/filtered_v4/subfigures_final/subfig_0_filelist_commercial_batch_0_1-PMC434155-0-pbiop0020251pg001.jpg",
"s... | 000084 | hf://datasets/vector-institute/open-pmc-18m@55d965cbdff6a9fc02c8057fafee9db0ce600386/data_00000.tar | |
{
"caption": "Fate of Membrane Protein during Lysosomal FusionLysosomal membranes in MEFs were labeled by transfecting cells with a vector encoding a CD63–GFP fusion protein, and expression was allowed for 48 h. For simultaneous labeling of lysosomal membrane and lumen, the CD63–GFP transfected cells were labeled wit... | 000085 | hf://datasets/vector-institute/open-pmc-18m@55d965cbdff6a9fc02c8057fafee9db0ce600386/data_00000.tar | |
{
"caption": "Presence of Syt VII Restricts the Size of the Fusion PoreThe lumen of lysosomes was loaded simultaneously using different-sized FITC- and TRITC-labeled dextran, using the approach described in Figures 1 and 2. Representative plots shown here demonstrate the fate of both dextran populations in individual... | 000086 | hf://datasets/vector-institute/open-pmc-18m@55d965cbdff6a9fc02c8057fafee9db0ce600386/data_00000.tar | |
{
"caption": "Overexpression of Apically Localizing Fz1/2 Chimeras Has an Inhibitory Effect on Canonical Wnt Signaling(A–D) show adult wings of the respective genotypes. Anterior is up and distal to the right.(A) Adult wing of an en-Gal4/+; UAS-fz1–1-1/+ fly (en>fz1–1-1). en-Gal4 drives UAS reporter genes only in the... | 000087 | hf://datasets/vector-institute/open-pmc-18m@55d965cbdff6a9fc02c8057fafee9db0ce600386/data_00000.tar | |
{
"caption": "Subcellular Localization of Fz1–1-1 in fmi− Mutant ClonesFz1–1-1 (Myc-tagged; shown in green) is expressed with omb-Gal4 (in large parts of the third instar wing pouch). fmiE59 clones were labeled by the absence of anti-βGal staining (red). A projection of several horizontal sections in the apical regio... | 000088 | hf://datasets/vector-institute/open-pmc-18m@55d965cbdff6a9fc02c8057fafee9db0ce600386/data_00000.tar | |
{
"caption": "The Cytoplasmic Region of Fz Regulates Subcellular LocalizationAll Fz1/2 chimeras shown are Myc-tagged (the tag being inserted right after the CRD of Fz1 or Fz2; see Materials and Methods; Boutros et al. 2000). The respective Fz1/2 chimeras, with their schematic structure shown under each photomicrograp... | 000089 | hf://datasets/vector-institute/open-pmc-18m@55d965cbdff6a9fc02c8057fafee9db0ce600386/data_00000.tar | |
{
"caption": "Rescue of the fz− Eye Phenotype with tub-Promoter-Driven Fz ChimerasTangential eye sections with corresponding schematic in lower part of panel reflecting ommatidial polarity (respective genotypes are also marked below each panel). Black arrows, dorsal chiral form; red arrows, ventral chiral form; green... | 000090 | hf://datasets/vector-institute/open-pmc-18m@55d965cbdff6a9fc02c8057fafee9db0ce600386/data_00000.tar | |
{
"caption": "Effects of Fz1/2 C-Tail Mutations on Subcellular Localization and PCP Activity(A) Sequence alignment of Fz1 and Fz2 C-tails. Note high degree of conservation within the membrane proximal shared portion of the Fz1 and Fz2 C-tails. The respective mutations generated and analyzed are indicated above the se... | 000091 | hf://datasets/vector-institute/open-pmc-18m@55d965cbdff6a9fc02c8057fafee9db0ce600386/data_00000.tar | |
{
"caption": "Epigenetic Imprints at the Initiation of X Inactivation(A–H) Indirect immunofluorescence and subsequent DNA FISH analysis on mitotic chromosomes prepared from undifferentiated clone 36 ES cells after 3 d of Xist induction. H3K27m3 (A), H4K20m1 (B), and Ezh2 (D) are enriched on the arms of Chromosome 11 ... | 000092 | hf://datasets/vector-institute/open-pmc-18m@55d965cbdff6a9fc02c8057fafee9db0ce600386/data_00000.tar | |
{
"caption": "hairy Affects stg-lacZ Reporter Expression(A–F) β-galactosidase expression from the stg-lacZ reporter lines pstg β-E4.9 (A and B), pstg β-E6.4 (C and D), and pstg β-E6.7 (E and F) in wild-type (A, C, and E) and hairy mutant (B, D, and F) embryos. Note the expanded (de-repressed) lacZ expression in the h... | 000093 | hf://datasets/vector-institute/open-pmc-18m@55d965cbdff6a9fc02c8057fafee9db0ce600386/data_00000.tar | |
{
"caption": "Hairy Binds to Putative Target Loci on Polytene Chromosomes(A) Hairy binds to polytene region 1A, the location of the Hairy target, ac.\n(B) Hairy is not found at 84A, the cytological location for ftz.\n(C–F) Hairy also binds to polytene region 99A, the location of stg (C); polytene region 3A, the locat... | 000094 | hf://datasets/vector-institute/open-pmc-18m@55d965cbdff6a9fc02c8057fafee9db0ce600386/data_00000.tar | |
{
"caption": "Hairy Target Gene Expression Is Disrupted in the Mutant Background of the Cofactors Associated with a Particular TargetWhole mount in situ hybridization on wild-type (A, E, and I), groucho germline clone(B, F, and J), dCtBP germline clone (C, G, and K), and dSir2 mutant (D, H, and L) embryos with probes... | 000095 | hf://datasets/vector-institute/open-pmc-18m@55d965cbdff6a9fc02c8057fafee9db0ce600386/data_00000.tar | |
{
"caption": "Expression of Hairy Target Genes Is Disrupted in hairy Mutant EmbryosWhole mount in situ hybridization on wild-type (A, C, E, G, I, K, and M) or hairy7H mutant (B, D, F, H, J, L, and N) embryos with probes recognizing prd (A and B), stg (C and D), ImpL2 (E and F), mae (G and H), egh (I and J), kayak (K ... | 000096 | hf://datasets/vector-institute/open-pmc-18m@55d965cbdff6a9fc02c8057fafee9db0ce600386/data_00000.tar | |
{
"caption": "Hairy Binds to Specific Loci on Polytene Chromosomes(A and B) Hairy staining (green) on third instar larval salivary gland polytene chromosome sets counterstained with DAPI (blue) to visualize the chromosomes.(C and D) Higher magnification of chromosome arms X, 3R (C) and 2L, 2R (D).",
"domain": null,... | 000097 | hf://datasets/vector-institute/open-pmc-18m@55d965cbdff6a9fc02c8057fafee9db0ce600386/data_00000.tar | |
{
"caption": "Polytene chromosomes (blue) stained for Hairy (green) and Groucho (red) binding",
"domain": "Other",
"primary_modality": "Other",
"secondary_modality": "Other",
"source_license": "other",
"subfigure_path": "/datasets/PMC-15M/filtered_biomedica/filtered_v4/subfigures_final/subfig_0_filelist_com... | 000098 | hf://datasets/vector-institute/open-pmc-18m@55d965cbdff6a9fc02c8057fafee9db0ce600386/data_00000.tar | |
{
"caption": "FISH Confirmation of a Human-Specific Duplication of a Gene Cluster on Chromosome 5q13.3 Detected by Interspecies cDNA aCGH(A) Human duplication of a cluster of genes at Chromosome 5q13.3. is shown by two separate, and sometimes multiple, red BAC probe (CTD-2288G5) signals in interphase cells, with only... | 000099 | hf://datasets/vector-institute/open-pmc-18m@55d965cbdff6a9fc02c8057fafee9db0ce600386/data_00000.tar |
OPEN-PMC
Arxiv: Arxiv | Code: Open-PMC Github | Model Checkpoint: Hugging Face
Dataset Summary
This dataset consists of image-text pairs extracted from medical papers available on PubMed Central. It has been curated to support research in medical image understanding, particularly in natural language processing (NLP) and computer vision tasks related to medical imagery. The dataset includes:
- Extracted images from research articles.
- Associated captions and sub-captions with each image.
- All pairs are filtered medical image-text pairs.
- All images are decomposed compound figures with their respective sub-captions.
- Summarized in-text references to corresponding images for better model training.
Supported Tasks and Benchmarks
This dataset is designed for research in:
- Medical Image Captioning: Training and evaluating models that generate descriptions for medical images.
- Multimodal Learning: Studying the relationship between medical images and their textual descriptions.
- Image-Text Retrieval: Enabling models to retrieve relevant images based on textual queries and vice versa.
- Medical Language Understanding: Assisting in understanding complex medical terminology in images.
Languages
The dataset primarily contains text in English.
Dataset Structure
Data Fields
Each record in the dataset contains:
- Image: Filename of each extracted and decomposed image.
- Full caption: Original figure caption from the research paper.
Data Splits
The dataset does not contain predefined splits. Users can split the data as needed for training, validation, and testing.
Dataset Creation
Source Data
Initial Data Collection and Processing
- Data Collection: We used the raw data provided in BIOMEDICA.
- Filtering: Non-medical image-text pairs were removed to ensure a focused dataset.
- Compound Figure Decomposition: Multi-panel figures were split into individual sub-figures.
Annotations
The dataset does not contain additional manual annotations.
Uses
This dataset is designed for research purposes only and should not be used for:
- Clinical diagnosis.
- Medical decision-making.
- Any real-world patient care applications.
Ethical Considerations
- This dataset is derived from open-access publications available on PubMed Central.
- Researchers should comply with ethical guidelines and ensure that their work does not imply clinical utility.
- The dataset is intended strictly for academic and research purposes.
Citation
If you find the code useful for your research, please consider citing
@article{baghbanzadeh2025open,
title={Open-PMC-18M: A High-Fidelity Large Scale Medical Dataset for Multimodal Representation Learning},
author={Baghbanzadeh, Negin and Ashkezari, Sajad and Dolatabadi, Elham and Afkanpour, Arash},
journal={arXiv preprint arXiv:2506.02738},
year={2025}
}
License
This dataset is licensed under CC-BY-4.0, meaning it can be used for research purposes with appropriate attribution.
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