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train · 48.9k rows

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ID stringlengths 13 17	question stringlengths 88 1.13k	answer stringlengths 6 156	reference_sequence stringlengths 4.1k 4.1k	variant_sequence stringlengths 4.1k 4.1k
Task1_train_35900	A genetic alteration is present on Chromosome 4. Is this variant benign or disease-causing, and if the latter, which condition is involved?	Benign	GATTTGACTGTTAGTAATGCCTAATGTTCATGGAGCACTCACTACGGGCCAGGCATCCTGCTAAACTCTTAGTATAGATTATCTTATTTAATCTACTTAATCCTCACAACAGCCCAATGAATAAACCATTATTATTATCTACATTCTACACAACTGAGGCAGAGAGAAGGTAAGTCACTTATCACTAACAGGTAACTCCAGCAGCACCAGTGGTCTTCCTGTTTCCCAGGGCACAATGTCAGTTCCTTTGTAAGGACCAAATAATCTAAGGGACATGTTCTCAAATTCCCAAGTGCACCATTCCACTATGTGGCACTGAG...	GATTTGACTGTTAGTAATGCCTAATGTTCATGGAGCACTCACTACGGGCCAGGCATCCTGCTAAACTCTTAGTATAGATTATCTTATTTAATCTACTTAATCCTCACAACAGCCCAATGAATAAACCATTATTATTATCTACATTCTACACAACTGAGGCAGAGAGAAGGTAAGTCACTTATCACTAACAGGTAACTCCAGCAGCACCAGTGGTCTTCCTGTTTCCCAGGGCACAATGTCAGTTCCTTTGTAAGGACCAAATAATCTAAGGGACATGTTCTCAAATTCCCAAGTGCACCATTCCACTATGTGGCACTGAG...
Task1_train_35901	This alteration on Chromosome 4 may affect genome function. Does it lead to a disease or is it benign?	Benign	AATGTAGGCTAAGCTGAATAAATACTGTTGAGGGCAAATCATGGGAATAAGAAATGACATTTAAGGATCTGATTTTTATGGACTAAGAGAAGACAGAATCTTGTTTTCCTTGTCAAGAAAGCAAAAGCTAACAAGGATTAAAAAATAAATGAGGCCAGAATCACAGAAGAGAGAGATGGGAAAGGGCCAAAGGTCACTTAACGCAAACCAAGATAGTATCAATCTTTGCAAACACCTGGGGACCTATTTTCCTGGTAGCAAGGTCGGATCCTGGGGATGAAAACTGTGTAGGAAAGGAAAGGACATTAAATCATGGAGGC...	AATGTAGGCTAAGCTGAATAAATACTGTTGAGGGCAAATCATGGGAATAAGAAATGACATTTAAGGATCTGATTTTTATGGACTAAGAGAAGACAGAATCTTGTTTTCCTTGTCAAGAAAGCAAAAGCTAACAAGGATTAAAAAATAAATGAGGCCAGAATCACAGAAGAGAGAGATGGGAAAGGGCCAAAGGTCACTTAACGCAAACCAAGATAGTATCAATCTTTGCAAACACCTGGGGACCTATTTTCCTGGTAGCAAGGTCGGATCCTGGGGATGAAAACTGTGTAGGAAAGGAAAGGACATTAAATCATGGAGGC...
Task1_train_35902	This sequence variant lies on Chromosome 4. Is it clinically significant, and what condition might it cause if any?	Benign	CACGCCTGTAGACCCAGCTACTTGGGAGGCTGAGGCAGGAGAATCACTTAAATTCGGCAGGTGGAGGTTGCAGTGAGCCGAGATTGTGCCACTGCACTCTAGGCTGGGCGACAAGCATGAAACTCCATCTCAAAAAAAAAGAAAAGAAAAGAAAAGAAAAAACCACCAACAAAATACCTCCTATTACCAGGAGCCCGGGAGCACTTTCCACAGCCGGGCTGCGTCATACTGCTTTAACTCCCTTACCCTCACAGCGCCTTCCTAGGTGGGTGTTACTAGCATGCCCAGAGGAGAGATGGAGAGCCAAGGTTCAGAGACAT...	CACGCCTGTAGACCCAGCTACTTGGGAGGCTGAGGCAGGAGAATCACTTAAATTCGGCAGGTGGAGGTTGCAGTGAGCCGAGATTGTGCCACTGCACTCTAGGCTGGGCGACAAGCATGAAACTCCATCTCAAAAAAAAAGAAAAGAAAAGAAAAGAAAAAACCACCAACAAAATACCTCCTATTACCAGGAGCCCGGGAGCACTTTCCACAGCCGGGCTGCGTCATACTGCTTTAACTCCCTTACCCTCACAGCGCCTTCCTAGGTGGGTGTTACTAGCATGCCCAGAGGAGAGATGGAGAGCCAAGGTTCAGAGACAT...
Task1_train_35903	The following genetic variant occurs on Chromosome 4. Classify its clinical effect — pathogenic or benign — and list any associated condition.	Benign	ATAGATAGATAGATACATAGATAGATAGATAGATACATACATACATACATACATACATACATAGATAATATTGAATGAATGGATGGATAGATGGTATCAAGTAATTACATGAAGGCATCATATAATTACAATAGGAAGAACTAACCTGTGCCTTCGGGAACTGTGCTCTGGGAACAGCCCTTACACCATTGCTCAGAAGAGGAAGCAGAGACCCTGAGGGCTGTGACTTGTCCCAGGCCCCACAAGAGGGAGTGGCCAAGGCAGGGACACACATGGCCAGAGCTCTTTCCTGTACAGTGTGCAGAAGGGCTATGCAAGAC...	ATAGATAGATAGATACATAGATAGATAGATAGATACATACATACATACATACATACATACATAGATAATATTGAATGAATGGATGGATAGATGGTATCAAGTAATTACATGAAGGCATCATATAATTACAATAGGAAGAACTAACCTGTGCCTTCGGGAACTGTGCTCTGGGAACAGCCCTTACACCATTGCTCAGAAGAGGAAGCAGAGACCCTGAGGGCTGTGACTTGTCCCAGGCCCCACAAGAGGGAGTGGCCAAGGCAGGGACACACATGGCCAGAGCTCTTTCCTGTACAGTGTGCAGAAGGGCTATGCAAGAC...
Task1_train_35904	Here is a mutation located on Chromosome 4. Determine whether it’s benign or pathogenic. If the latter, what disease does it cause?	Benign	TTTTGTTCTGAGAATGTTCTATCCTGTCCTTATTTTATGAATGGAATACCTTCTCTGATCTCTCTGATAATATTTTAGTTGTTTATTTGTTTAAAGTTTTTTTTCCCTGTGTAGTGCGTTCCCTGCTTGCTTTTTCCTTTTGTTTGTTTTGGATTTTATCTTTCATATTAGAGTCTGTCCTCAAATGGCTAGTGACCCTCTAGACATTTTCAAGTGATGCTGATGCTCCCTCTGTGGGATATATATATTTTTTCCTCAATGTCTTTACTGTAGGACTATCTGACTGGGTTCTTCTTTGCAGGACCCTTGTACTGGTCTGC...	TTTTGTTCTGAGAATGTTCTATCCTGTCCTTATTTTATGAATGGAATACCTTCTCTGATCTCTCTGATAATATTTTAGTTGTTTATTTGTTTAAAGTTTTTTTTCCCTGTGTAGTGCGTTCCCTGCTTGCTTTTTCCTTTTGTTTGTTTTGGATTTTATCTTTCATATTAGAGTCTGTCCTCAAATGGCTAGTGACCCTCTAGACATTTTCAAGTGATGCTGATGCTCCCTCTGTGGGATATATATATTTTTTCCTCAATGTCTTTACTGTAGGACTATCTGACTGGGTTCTTCTTTGCAGGACCCTTGTACTGGTCTGC...
Task1_train_35905	A variant was discovered on Chromosome 4. Please indicate if this mutation results in a known disease or if it's non-harmful.	Benign	GATGTGCATTTCTCTGATGGCCAGTGATGATGAGCATTTTTTCATGTGTTTTTTGGCTGCATCAATGTCTTCTTTTGAGAAGTGTCTGTTCATGTCCTTCGCCCACTTTTTGATGGGGTTGTTTGTTTTTTTCTTGTAAATGTGTTTGAGTTCATTGTAGATTCTGGATATTAGCCCTTTGTCAGATGAGTAGGTTGGGAAAATGTTCTCCCATTTTGTAGGTTGCCTGTTCACTCTGATGGTAGTTTCTTTTGCTGTGCAGAAGCTCTTTAGTTTAATGAGATCCCATTTGTCAATTTTGGCTTTTGTTGCCATTGCTT...	GATGTGCATTTCTCTGATGGCCAGTGATGATGAGCATTTTTTCATGTGTTTTTTGGCTGCATCAATGTCTTCTTTTGAGAAGTGTCTGTTCATGTCCTTCGCCCACTTTTTGATGGGGTTGTTTGTTTTTTTCTTGTAAATGTGTTTGAGTTCATTGTAGATTCTGGATATTAGCCCTTTGTCAGATGAGTAGGTTGGGAAAATGTTCTCCCATTTTGTAGGTTGCCTGTTCACTCTGATGGTAGTTTCTTTTGCTGTGCAGAAGCTCTTTAGTTTAATGAGATCCCATTTGTCAATTTTGGCTTTTGTTGCCATTGCTT...
Task1_train_35906	Mutation context: Chromosome 4. Determine if this variant is likely to be benign or pathogenic. Mention the disease if applicable.	Benign	TTTACTGAAAAAGTTTGCTAACCCCTGCATTTAAAAATGCCTTACCAGGCGGGATGCAGTGACTCATGCCTATAATCCCAGCACTTTGGGAGGTGGAGGCAGGCAGGTTGCATGAGTTCAGGAGTTCGAGACCAGCCTGGGCAACACAGAGAAACCCCATCTCAAAAAAAAAAAAAAAAGCCTTACCGGTTCACCAAAGAAAAAGAAAATGCCTTATTATATCTAAATGACCATATTATATCTAAATGACCTTTGACAAAGAGGCAAAAGCACTTCAATGGAGGAATGATAAGCTTTTCAATAAATGGTACTGGAGCAAT...	TTTACTGAAAAAGTTTGCTAACCCCTGCATTTAAAAATGCCTTACCAGGCGGGATGCAGTGACTCATGCCTATAATCCCAGCACTTTGGGAGGTGGAGGCAGGCAGGTTGCATGAGTTCAGGAGTTCGAGACCAGCCTGGGCAACACAGAGAAACCCCATCTCAAAAAAAAAAAAAAAAGCCTTACCGGTTCACCAAAGAAAAAGAAAATGCCTTATTATATCTAAATGACCATATTATATCTAAATGACCTTTGACAAAGAGGCAAAAGCACTTCAATGGAGGAATGATAAGCTTTTCAATAAATGGTACTGGAGCAAT...
Task1_train_35907	Here is a mutation located on Chromosome 4. Determine whether it’s benign or pathogenic. If the latter, what disease does it cause?	Benign	ACAGGGCTACACAGTCTATGTTTGTATAGAAGAGGGATGGATTCACTATGCCTGCATACCGGGCACCAAAGGGAAAAAAGATGGCTTCCGTATCTCAGAACACAGAAGAGTTGGAATTCCCAGGGCGGCATCCCATCTTTCTGGCCTGGGCATTTGGAGCTGAAATGTGCATCTGTAAATATTAAAACTGGAAGAGCCCTTCAAAGGGACCCTGACGGTCATCAGATTCAGTTTCTTGAGACTCACAGGAAAAAAAACAGCTGCCAAGACAGATGGGACTGGCTGTAGATAATGGTGAAAACAGCTGACACTCAGGGAGG...	ACAGGGCTACACAGTCTATGTTTGTATAGAAGAGGGATGGATTCACTATGCCTGCATACCGGGCACCAAAGGGAAAAAAGATGGCTTCCGTATCTCAGAACACAGAAGAGTTGGAATTCCCAGGGCGGCATCCCATCTTTCTGGCCTGGGCATTTGGAGCTGAAATGTGCATCTGTAAATATTAAAACTGGAAGAGCCCTTCAAAGGGACCCTGACGGTCATCAGATTCAGTTTCTTGAGACTCACAGGAAAAAAAACAGCTGCCAAGACAGATGGGACTGGCTGTAGATAATGGTGAAAACAGCTGACACTCAGGGAGG...
Task1_train_35908	This variant is found on Chromosome 4. What is the clinical effect of this variant — benign or pathogenic? State the disease if applicable.	Benign	TGAGGGTGGGGACAAGCAGGGAAGGACCACAGAACCCATGAGGACATAGAAGGACCTGGCTGGGCAGGGGAGTGAGAGGAGGCAGTGAGGGTGTTCCAGGAGGAAGGCCCCGCATGTGCAGAGGCTGGGCAGCCGGGACCAGGCAGGTGTGCAGGACAGGGCCCCACAGAACTTCCTGCACCATGCCTGGGGTGCTGGACTTGATCTCAGGGCAGCAACAGGAGGGTTTGGGGCCATGGCTGACAGAACCATCAGCATCTCTGAAAGGTCCGCTGTTCTGTGAGGTGGGGTTAGAGCATGGGGCAGAGATGGGAGGCTGG...	TGAGGGTGGGGACAAGCAGGGAAGGACCACAGAACCCATGAGGACATAGAAGGACCTGGCTGGGCAGGGGAGTGAGAGGAGGCAGTGAGGGTGTTCCAGGAGGAAGGCCCCGCATGTGCAGAGGCTGGGCAGCCGGGACCAGGCAGGTGTGCAGGACAGGGCCCCACAGAACTTCCTGCACCATGCCTGGGGTGCTGGACTTGATCTCAGGGCAGCAACAGGAGGGTTTGGGGCCATGGCTGACAGAACCATCAGCATCTCTGAAAGGTCCGCTGTTCTGTGAGGTGGGGTTAGAGCATGGGGCAGAGATGGGAGGCTGG...
Task1_train_35909	This sequence change occurs on Chromosome 4. What is the medical significance of this variant — is it benign or linked to a disease?	Benign	CGCTGCCTTTTGTCCGGTGCCTGAGAAGCCATGGAGAAAGGCAGAGGGGACCACAGGGAGAAGAGGAAGGAGTAGGGGAGAGGAACGGGAGAGGTGAAGCGACCAGCGTCCCCAAGGGTCAGGGCGCAGCTGCGGGGCTGGCCCAGGCTGCGCCCTGGGGGAGATGCTGGCGTTGGTGACATTGACCGCAGTTCCAGAGGAACTCTCCTTGGGACAGCTACGGGCCGTGCACAAAGCGCCCTCGCCTCCCTAGTACTCCACCACGCTTTGAGGAAGGCCGGAAGAAGACGGCCACCCCCATCTGACAGATGGAGAAGCTG...	CGCTGCCTTTTGTCCGGTGCCTGAGAAGCCATGGAGAAAGGCAGAGGGGACCACAGGGAGAAGAGGAAGGAGTAGGGGAGAGGAACGGGAGAGGTGAAGCGACCAGCGTCCCCAAGGGTCAGGGCGCAGCTGCGGGGCTGGCCCAGGCTGCGCCCTGGGGGAGATGCTGGCGTTGGTGACATTGACCGCAGTTCCAGAGGAACTCTCCTTGGGACAGCTACGGGCCGTGCACAAAGCGCCCTCGCCTCCCTAGTACTCCACCACGCTTTGAGGAAGGCCGGAAGAAGACGGCCACCCCCATCTGACAGATGGAGAAGCTG...
Task1_train_35910	A mutation located on Chromosome 4 is being studied. Determine whether it’s pathogenic or benign, and specify the linked disease.	Benign	AACGGGGCCACAGGGTCTCCAGGGGGGTCCCTGAAAACCTAGGTGGACAGCATCATCTTCACTTCTTCCCCAGCAGCATCCAGCCAGACACTCGCACAGCAGTCACTAAATGCATATTGAATAAATAAATAAATAGACAGATCTGTGGGTAAATCAATCCAGGAATACATGGATGAATGTGCTAACCCATCAGAAAACCCCATAAACGAATTTAAAGGGTGGAACTCAATGTGCTGAGGCTGCCTTTCTTACGTCTCAATGGCTCCCCAATTTTCCTCGAAATAAAACCCACTAGTTTCTATAATTGTACAACATAAGTC...	AACGGGGCCACAGGGTCTCCAGGGGGGTCCCTGAAAACCTAGGTGGACAGCATCATCTTCACTTCTTCCCCAGCAGCATCCAGCCAGACACTCGCACAGCAGTCACTAAATGCATATTGAATAAATAAATAAATAGACAGATCTGTGGGTAAATCAATCCAGGAATACATGGATGAATGTGCTAACCCATCAGAAAACCCCATAAACGAATTTAAAGGGTGGAACTCAATGTGCTGAGGCTGCCTTTCTTACGTCTCAATGGCTCCCCAATTTTCCTCGAAATAAAACCCACTAGTTTCTATAATTGTACAACATAAGTC...
Task1_train_35911	A genetic alteration is present on Chromosome 4. Is this variant benign or disease-causing, and if the latter, which condition is involved?	Benign	GGATATTTAAAAATTAATAGTCCAGTGTATACATCATTCTCTGTAAGTTTGGTCATTGTAAGTCAGCCGATCCAACCCCAGTGAACATTTCAATTCTAGTTCCAGGGCCTGTGAGAGTGAGGAGCAGCCCTTGGAAGGTGGGCTGCTGCTATGATGTCCCCACAGCAGCCAGCCAGCCGGCCTTCCAGGGTGACACCTGCTGCATTTGCAATTTGATACTTTCACAACCTGGAACTCTGCTTTCGATTTTTTTTTTTTTTTTTGACACAGTCTTGCTCTGTCACCAGGCTGGAGTGCAGTGGTGTGATCTCGGCTCACTG...	GGATATTTAAAAATTAATAGTCCAGTGTATACATCATTCTCTGTAAGTTTGGTCATTGTAAGTCAGCCGATCCAACCCCAGTGAACATTTCAATTCTAGTTCCAGGGCCTGTGAGAGTGAGGAGCAGCCCTTGGAAGGTGGGCTGCTGCTATGATGTCCCCACAGCAGCCAGCCAGCCGGCCTTCCAGGGTGACACCTGCTGCATTTGCAATTTGATACTTTCACAACCTGGAACTCTGCTTTCGATTTTTTTTTTTTTTTTTGACACAGTCTTGCTCTGTCACCAGGCTGGAGTGCAGTGGTGTGATCTCGGCTCACTG...
Task1_train_35912	This alteration occurs on Chromosome 4. Is it associated with a disease or is it a benign variant?	Benign	GGACAAATGTATAACTGAAAAACTCCAGAGATGCTTAGAAATCAAGCAACATATTTCTAAATAACCCAATGGGTCAAAGAAGAAATCATAATAGAAATTAGAAGCTATTTTAGGTTTTTTGTTGTTGTTGTTGCTTGTTTTTATTTCATCCTTTTGGACTTTAATTTCTAAATCAATACAACAGGGCTAGCTATAACAACGTCATTTTTTTTTTTTTTTTTTGAGACAGAGTCTTGCTCTGTTGCCCAGGCTGGAGTGCAGTGGCACAATCTCGGCTCACTGCAACCTCCGCCTCCCAGGTTCAAGCAATTCTCCTGCCT...	GGACAAATGTATAACTGAAAAACTCCAGAGATGCTTAGAAATCAAGCAACATATTTCTAAATAACCCAATGGGTCAAAGAAGAAATCATAATAGAAATTAGAAGCTATTTTAGGTTTTTTGTTGTTGTTGTTGCTTGTTTTTATTTCATCCTTTTGGACTTTAATTTCTAAATCAATACAACAGGGCTAGCTATAACAACGTCATTTTTTTTTTTTTTTTTTGAGACAGAGTCTTGCTCTGTTGCCCAGGCTGGAGTGCAGTGGCACAATCTCGGCTCACTGCAACCTCCGCCTCCCAGGTTCAAGCAATTCTCCTGCCT...
Task1_train_35913	This variant is located on Chromosome 4. Evaluate its biological effect and specify any disease association.	Benign	GCTGAGGCAGGAGAACTGCTTGAACCTGGGAGGTGGAGGTTACAGTGAGCCGAGATCCCACCACTGCACTCCAGCCTGGGTGACAGAGCGAGACTCTGTCTCACAAAAAAAAAAAAAAAAAAAAAAAGAATACAATAAAGGTCTAAGAAGAAACCAATAAATCAAATACAAACAATAAATAAAATCAATAAAAGTAAAAACAGATTCTTTGAAATGACTGATAACATTGTTGGGGGTGGGGAGGAAAGAGAGAAAGGAAAGAAGGAAGAGAGAGACAAAGAGAGAAAGAGGGAAAGGAAGGCAGGAGGGGGAGAGCAAGA...	GCTGAGGCAGGAGAACTGCTTGAACCTGGGAGGTGGAGGTTACAGTGAGCCGAGATCCCACCACTGCACTCCAGCCTGGGTGACAGAGCGAGACTCTGTCTCACAAAAAAAAAAAAAAAAAAAAAAAGAATACAATAAAGGTCTAAGAAGAAACCAATAAATCAAATACAAACAATAAATAAAATCAATAAAAGTAAAAACAGATTCTTTGAAATGACTGATAACATTGTTGGGGGTGGGGAGGAAAGAGAGAAAGGAAAGAAGGAAGAGAGAGACAAAGAGAGAAAGAGGGAAAGGAAGGCAGGAGGGGGAGAGCAAGA...
Task1_train_35914	Here is a genetic alteration on Chromosome 4. Based on the data, is it a benign variant or a cause of disease?	Benign	GCAGGAGGGGGAGAGCAAGAGACAGAAAGATGGAGAAGGAGACACAGAGACAGGAAAGGAGGGAGAGAGGGTGGAGCGAGATGGGAGAGAGAAATAGAGATAGAAAATGGAATGAATGAATGCCAGGGTCTCAACGCTAAATATCCTACACATGGTGAAGGCCACCGTAGGAACATTATGAGTGTTTTATCCCAAGACTCCCAACAGTCAAGAACTGTCCACAGATGAGGAGAGTGACTCAAGCGAAGTCTGCATGTGGCCTAAAAGTCACAGCTCTGAAAGCACAGAGCCGGGTTGGAACCTGGTTTTATCATGCTCTA...	GCAGGAGGGGGAGAGCAAGAGACAGAAAGATGGAGAAGGAGACACAGAGACAGGAAAGGAGGGAGAGAGGGTGGAGCGAGATGGGAGAGAGAAATAGAGATAGAAAATGGAATGAATGAATGCCAGGGTCTCAACGCTAAATATCCTACACATGGTGAAGGCCACCGTAGGAACATTATGAGTGTTTTATCCCAAGACTCCCAACAGTCAAGAACTGTCCACAGATGAGGAGAGTGACTCAAGCGAAGTCTGCATGTGGCCTAAAAGTCACAGCTCTGAAAGCACAGAGCCGGGTTGGAACCTGGTTTTATCATGCTCTA...
Task1_train_35915	A mutation on Chromosome 4 is under examination. Does this mutation cause a disorder, or is it a benign change?	Benign	AATAGAGATAGAAAATGGAATGAATGAATGCCAGGGTCTCAACGCTAAATATCCTACACATGGTGAAGGCCACCGTAGGAACATTATGAGTGTTTTATCCCAAGACTCCCAACAGTCAAGAACTGTCCACAGATGAGGAGAGTGACTCAAGCGAAGTCTGCATGTGGCCTAAAAGTCACAGCTCTGAAAGCACAGAGCCGGGTTGGAACCTGGTTTTATCATGCTCTACAGTCCATTGTTCTTTTCATTGCAACTTTCAAGACCCAATGTACAGAATTAGTACTTGGAGCACTTGAAAAACCCCAGGGTTGGAAAATGCA...	AATAGAGATAGAAAATGGAATGAATGAATGCCAGGGTCTCAACGCTAAATATCCTACACATGGTGAAGGCCACCGTAGGAACATTATGAGTGTTTTATCCCAAGACTCCCAACAGTCAAGAACTGTCCACAGATGAGGAGAGTGACTCAAGCGAAGTCTGCATGTGGCCTAAAAGTCACAGCTCTGAAAGCACAGAGCCGGGTTGGAACCTGGTTTTATCATGCTCTACAGTCCATTGTTCTTTTCATTGCAACTTTCAAGACCCAATGTACAGAATTAGTACTTGGAGCACTTGAAAAACCCCAGGGTTGGAAAATGCA...
Task1_train_35916	A variant on Chromosome 4 has been observed. Is this a neutral mutation, or does it result in a disease? If so, which one?	Benign	ATTATGAGTGTTTTATCCCAAGACTCCCAACAGTCAAGAACTGTCCACAGATGAGGAGAGTGACTCAAGCGAAGTCTGCATGTGGCCTAAAAGTCACAGCTCTGAAAGCACAGAGCCGGGTTGGAACCTGGTTTTATCATGCTCTACAGTCCATTGTTCTTTTCATTGCAACTTTCAAGACCCAATGTACAGAATTAGTACTTGGAGCACTTGAAAAACCCCAGGGTTGGAAAATGCAAGGGCTGATCTTAAAGTGTGAACACCCCGTGGGTGCCCTGCTGGAGTCTAAGAAGAGGGGCAGGCTTGAATCTCCCATAGCA...	ATTATGAGTGTTTTATCCCAAGACTCCCAACAGTCAAGAACTGTCCACAGATGAGGAGAGTGACTCAAGCGAAGTCTGCATGTGGCCTAAAAGTCACAGCTCTGAAAGCACAGAGCCGGGTTGGAACCTGGTTTTATCATGCTCTACAGTCCATTGTTCTTTTCATTGCAACTTTCAAGACCCAATGTACAGAATTAGTACTTGGAGCACTTGAAAAACCCCAGGGTTGGAAAATGCAAGGGCTGATCTTAAAGTGTGAACACCCCGTGGGTGCCCTGCTGGAGTCTAAGAAGAGGGGCAGGCTTGAATCTCCCATAGCA...
Task1_train_35917	This sequence change occurs on Chromosome 4. What is the medical significance of this variant — is it benign or linked to a disease?	Benign	GCGTGATGAGTAAGCAGATATGCAGACCCAACCTACCATGGGGCCATTGCTCAGGGAGCTCAGAGCTTGCCCCTGAGCCACAGAACACCTGGGCCTCTTCTCCTCTTTCTCCAAATGTGCTTCTTTCACTTCTGCTCCACTGACATTTCCTTGCAGGGCATTGGCTACACCAGTGTTTCTCCAGACCAGCGATGGAGGGGGAGAATCAGCACCGCGTCTGGAATTCCCGGTGCCTGTGGAAGGTCCTGTCTGCCCTGCAGCCAGACTCATTTCCTCCTCCAAGGGTGGCCCACAGGCTCTTGAAAGCAGCTGTCCTGTGA...	GCGTGATGAGTAAGCAGATATGCAGACCCAACCTACCATGGGGCCATTGCTCAGGGAGCTCAGAGCTTGCCCCTGAGCCACAGAACACCTGGGCCTCTTCTCCTCTTTCTCCAAATGTGCTTCTTTCACTTCTGCTCCACTGACATTTCCTTGCAGGGCATTGGCTACACCAGTGTTTCTCCAGACCAGCGATGGAGGGGGAGAATCAGCACCGCGTCTGGAATTCCCGGTGCCTGTGGAAGGTCCTGTCTGCCCTGCAGCCAGACTCATTTCCTCCTCCAAGGGTGGCCCACAGGCTCTTGAAAGCAGCTGTCCTGTGA...
Task1_train_35918	A mutation found on Chromosome 4 may be clinically relevant. Is it pathogenic or benign, and if the former, which disease is implicated?	Benign	TCTGGAATTCCCGGTGCCTGTGGAAGGTCCTGTCTGCCCTGCAGCCAGACTCATTTCCTCCTCCAAGGGTGGCCCACAGGCTCTTGAAAGCAGCTGTCCTGTGAGTGGAGTCACCTGCACCTCTTTGTCTAGAGCGTGCATCTTGGCTTTTCCCTGGAGGTGCTCCCTTCCCCTCACCAAACGCCCCTGATCCGTGCTCCTCTGCAAGGTGACTTCCCTCTCCAGGACATGGACCCTGCGTAGAAGGTGCTCGTTCTCCCCACTTAAGGCCCGGATCATGTCTTCTATTCCTAGCACGATATCCTTTATCAGCTCTTTAT...	TCTGGAATTCCCGGTGCCTGTGGAAGGTCCTGTCTGCCCTGCAGCCAGACTCATTTCCTCCTCCAAGGGTGGCCCACAGGCTCTTGAAAGCAGCTGTCCTGTGAGTGGAGTCACCTGCACCTCTTTGTCTAGAGCGTGCATCTTGGCTTTTCCCTGGAGGTGCTCCCTTCCCCTCACCAAACGCCCCTGATCCGTGCTCCTCTGCAAGGTGACTTCCCTCTCCAGGACATGGACCCTGCGTAGAAGGTGCTCGTTCTCCCCACTTAAGGCCCGGATCATGTCTTCTATTCCTAGCACGATATCCTTTATCAGCTCTTTAT...
Task1_train_35919	This variant is present on Chromosome 4. Is the change likely to result in a pathogenic outcome?	Benign	GGCTTTTCCCTGGAGGTGCTCCCTTCCCCTCACCAAACGCCCCTGATCCGTGCTCCTCTGCAAGGTGACTTCCCTCTCCAGGACATGGACCCTGCGTAGAAGGTGCTCGTTCTCCCCACTTAAGGCCCGGATCATGTCTTCTATTCCTAGCACGATATCCTTTATCAGCTCTTTATAACTGACGCCAAGCTCCGAGATCAGTGTCTGGAGCTTCCAGTTTTCCAGGGTGACTTGCTCCATCGTGTCTTTGGATTTCCTGACACTCTCAGACGTGGCTTTCTGGAGTTGGCCCAGATTCCCTTTCAGTGTTTCATTTTCCT...	GGCTTTTCCCTGGAGGTGCTCCCTTCCCCTCACCAAACGCCCCTGATCCGTGCTCCTCTGCAAGGTGACTTCCCTCTCCAGGACATGGACCCTGCGTAGAAGGTGCTCGTTCTCCCCACTTAAGGCCCGGATCATGTCTTCTATTCCTAGCACGATATCCTTTATCAGCTCTTTATAACTGACGCCAAGCTCCGAGATCAGTGTCTGGAGCTTCCAGTTTTCCAGGGTGACTTGCTCCATCGTGTCTTTGGATTTCCTGACACTCTCAGACGTGGCTTTCTGGAGTTGGCCCAGATTCCCTTTCAGTGTTTCATTTTCCT...
Task1_train_35920	A mutation is present on Chromosome 4. Based on this information, is the variant pathogenic or benign? Provide the disease if relevant.	Benign	TTACGACTGCCTCAGCCTCAGAGCGAGCCATGGGAGGTGAGTTGGGACGCAGGCTCCTGACCCTCAGGGCCAGCATGGGGCAGTGTGGGCCGTCGAGCCTGGATCTCGGGGTCCACCTCCAAGCTGGGGACCTTGGGGAGTCACAGCAGCCCTTGGAGTCTCATCTCCTCTCCAGAGCAGAGGTGGCAGCAACACCTCGTGGGTGTCAGGAGGTGTCAACGAGATGAAGCCTGTTCCGTGGAAGCCCAGGCCTGGCACCCAGTTAACCCCCTTCCTCCCCACCCCCCATCCAGGTCTCAGGATGTTTCATTTCCTCTCCT...	TTACGACTGCCTCAGCCTCAGAGCGAGCCATGGGAGGTGAGTTGGGACGCAGGCTCCTGACCCTCAGGGCCAGCATGGGGCAGTGTGGGCCGTCGAGCCTGGATCTCGGGGTCCACCTCCAAGCTGGGGACCTTGGGGAGTCACAGCAGCCCTTGGAGTCTCATCTCCTCTCCAGAGCAGAGGTGGCAGCAACACCTCGTGGGTGTCAGGAGGTGTCAACGAGATGAAGCCTGTTCCGTGGAAGCCCAGGCCTGGCACCCAGTTAACCCCCTTCCTCCCCACCCCCCATCCAGGTCTCAGGATGTTTCATTTCCTCTCCT...
Task1_train_35921	A change on Chromosome 4 is being evaluated. Identify whether the variant is neutral or disease-linked. Mention the disease if applicable.	Benign	AAACAATAAACTTTGGACTCTCATCAAATTTTGATCACATTCCAGTTCAGTCCCTTAATAGCTGTGTGACAACAGTTAAAAGATGCTGTCCTCTGAGCCTCAGCTTCTTCAAATGCAAAAGGAAGATGCGAATATCACCTGCCTTCATAAGCATTACATGAAATAATGTCTTTGCAAACACCCAGTATGGAGCCGAGCACACAGTAGGAATACATAAAATGTAAGCTTTTACCCTCCCCTCAATCAAATGAATCAACACATGTCCAGCCTGCCCTCCAGAGTTTAAGAAGCTTGCCCAAGGTCACACAGCGAGTAAATAT...	AAACAATAAACTTTGGACTCTCATCAAATTTTGATCACATTCCAGTTCAGTCCCTTAATAGCTGTGTGACAACAGTTAAAAGATGCTGTCCTCTGAGCCTCAGCTTCTTCAAATGCAAAAGGAAGATGCGAATATCACCTGCCTTCATAAGCATTACATGAAATAATGTCTTTGCAAACACCCAGTATGGAGCCGAGCACACAGTAGGAATACATAAAATGTAAGCTTTTACCCTCCCCTCAATCAAATGAATCAACACATGTCCAGCCTGCCCTCCAGAGTTTAAGAAGCTTGCCCAAGGTCACACAGCGAGTAAATAT...
Task1_train_35922	A variant affecting Chromosome 4 has been observed. Determine if it's benign or associated with disease.	Benign	CTGGTCCTCCAGAGCTGATAGCCAGGCTGTTGGCAGGTGAGGGCCACATTCTGGTGTTGTCACCTAGTTGCCATTCACCTGGGATCCCTCCTTGGCCTTCTGGTGGGCCTGGTGGAGAGAACCTGCCCCAGGGGATTTGTGGGGTCTGGTGCTTCCCCGAGGCCCGGAGCTGATGGGGGGCTCCAGCCTGGATGTGTCATGTAGCCCCTCAGTGGGCCCTGGACATGCAGCCAGGCTTCCCTACCCCCATGTGGGGCCGCCCCCTAGGCGTCCACTTCCTGGTGTTGGTCCAGGCCCCTGGCACTTCTGAAGATGCACAG...	CTGGTCCTCCAGAGCTGATAGCCAGGCTGTTGGCAGGTGAGGGCCACATTCTGGTGTTGTCACCTAGTTGCCATTCACCTGGGATCCCTCCTTGGCCTTCTGGTGGGCCTGGTGGAGAGAACCTGCCCCAGGGGATTTGTGGGGTCTGGTGCTTCCCCGAGGCCCGGAGCTGATGGGGGGCTCCAGCCTGGATGTGTCATGTAGCCCCTCAGTGGGCCCTGGACATGCAGCCAGGCTTCCCTACCCCCATGTGGGGCCGCCCCCTAGGCGTCCACTTCCTGGTGTTGGTCCAGGCCCCTGGCACTTCTGAAGATGCACAG...
Task1_train_35923	A variant on Chromosome 4 is under investigation. Evaluate whether it is clinically benign or pathogenic and name the disorder if relevant.	Benign	ACTTTGTCCCCCATCCCCTCCAGTCCCTCTGCCTGGCTGCCCTGTGTTCTGGCAGGGCTCAGGGCCTCTGAGTTCTGCACAGACCAGGAAGGCATGAGGGCTGGCCCTGGGTGGCAGCGCTGCTTCACCCCATCCTGAGGCTGCTCCCAGCATGCCTCCCTCAGCCCTCTGCTCCTCTTGGCTGTGGTGAAGGCCAAGAGCTCTTTCTGACCTTAGCGCTGCATGCAGAGCAGGGGAGCAGGACCCACAGGTCGGGGGAAGGCAGCCTTTGGCCTTGACTATGGGGAGGTAGGGGTGCGCTGGTGTGTATGTGTAGGTGC...	ACTTTGTCCCCCATCCCCTCCAGTCCCTCTGCCTGGCTGCCCTGTGTTCTGGCAGGGCTCAGGGCCTCTGAGTTCTGCACAGACCAGGAAGGCATGAGGGCTGGCCCTGGGTGGCAGCGCTGCTTCACCCCATCCTGAGGCTGCTCCCAGCATGCCTCCCTCAGCCCTCTGCTCCTCTTGGCTGTGGTGAAGGCCAAGAGCTCTTTCTGACCTTAGCGCTGCATGCAGAGCAGGGGAGCAGGACCCACAGGTCGGGGGAAGGCAGCCTTTGGCCTTGACTATGGGGAGGTAGGGGTGCGCTGGTGTGTATGTGTAGGTGC...
Task1_train_35924	Here’s a variant located on Chromosome 4. What is the predicted biological effect — harmless or disease-causing?	Benign	CCTGAGGCTGCTCCCAGCATGCCTCCCTCAGCCCTCTGCTCCTCTTGGCTGTGGTGAAGGCCAAGAGCTCTTTCTGACCTTAGCGCTGCATGCAGAGCAGGGGAGCAGGACCCACAGGTCGGGGGAAGGCAGCCTTTGGCCTTGACTATGGGGAGGTAGGGGTGCGCTGGTGTGTATGTGTAGGTGCACACGTGTAGGGGTGGGTGTGCATGTGTGAGGGTGCACGTGTGGGGGTGGGTGTGCACGTGTGTGTAGGGGTGGGTTGCGTGTGTGTGAATGTGTATAGGGGTGGGTTGTGTGAATGTGTGTGTAGGGGTGGG...	CCTGAGGCTGCTCCCAGCATGCCTCCCTCAGCCCTCTGCTCCTCTTGGCTGTGGTGAAGGCCAAGAGCTCTTTCTGACCTTAGCGCTGCATGCAGAGCAGGGGAGCAGGACCCACAGGTCGGGGGAAGGCAGCCTTTGGCCTTGACTATGGGGAGGTAGGGGTGCGCTGGTGTGTATGTGTAGGTGCACACGTGTAGGGGTGGGTGTGCATGTGTGAGGGTGCACGTGTGGGGGTGGGTGTGCACGTGTGTGTAGGGGTGGGTTGCGTGTGTGTGAATGTGTATAGGGGTGGGTTGTGTGAATGTGTGTGTAGGGGTGGG...
Task1_train_35925	This is a variant located on Chromosome 4. Is this mutation a likely cause of disease or not?	Benign	GAGTGGGAGAGGGAAGGGGCCTGGAGACCCTTGGGAATAAATCGCTCCTCATCCTTGTCTTGCGGAGCTGCCTCTTGTCCAATCACCTCCCGTTCACCCCGTGGTGAGGGAGGGGTCCTCACCCTAAATGGTAGATGGTTGAATACACACCACCCTACCCAGCACAGGTGACGTCCATAGCAGCTTCTGTTTATCACATACAATCACAGCTCACACCTTACTCGCCAAGGCCCCGTGGGAGTGCACTGTGGAGCGGACTGAACACGCAGGGGCAGCTGGGTAGCAGCAAGGGGGCGGGTGCCCTCCGACTCCTGCAGAGG...	GAGTGGGAGAGGGAAGGGGCCTGGAGACCCTTGGGAATAAATCGCTCCTCATCCTTGTCTTGCGGAGCTGCCTCTTGTCCAATCACCTCCCGTTCACCCCGTGGTGAGGGAGGGGTCCTCACCCTAAATGGTAGATGGTTGAATACACACCACCCTACCCAGCACAGGTGACGTCCATAGCAGCTTCTGTTTATCACATACAATCACAGCTCACACCTTACTCGCCAAGGCCCCGTGGGAGTGCACTGTGGAGCGGACTGAACACGCAGGGGCAGCTGGGTAGCAGCAAGGGGGCGGGTGCCCTCCGACTCCTGCAGAGG...
Task1_train_35926	A mutation located on Chromosome 4 is being studied. Determine whether it’s pathogenic or benign, and specify the linked disease.	Benign	CAGAGCAAGACCCTGTCTGTAAAAGAAACAGAGGTGGGAATGCTGGAAGGGGCTGCCCAGGTTGGAGAGCTCCAGACAAGGGTTCCATGGCTGCTACCCCGAGGCTGCACAGTGTGAGCAAGGAAGGCACTTAACTGGGGGTTCTCCACACCCCCAGCCTAAGGCAAACAGAGAAAGATGTTAAATACTGAGCCTGTCTTTATTTAAAACTCTGACATTTTGTTCCTCATGGGTTTTTTGCATTAATTTTCATTTTTTAAAGTACTGCATTAAAATATCATTTATCTCAACTACTAAGAATTGAGGCACCCCCATAAATT...	CAGAGCAAGACCCTGTCTGTAAAAGAAACAGAGGTGGGAATGCTGGAAGGGGCTGCCCAGGTTGGAGAGCTCCAGACAAGGGTTCCATGGCTGCTACCCCGAGGCTGCACAGTGTGAGCAAGGAAGGCACTTAACTGGGGGTTCTCCACACCCCCAGCCTAAGGCAAACAGAGAAAGATGTTAAATACTGAGCCTGTCTTTATTTAAAACTCTGACATTTTGTTCCTCATGGGTTTTTTGCATTAATTTTCATTTTTTAAAGTACTGCATTAAAATATCATTTATCTCAACTACTAAGAATTGAGGCACCCCCATAAATT...
Task1_train_35927	The following genetic variant occurs on Chromosome 4. Classify its clinical effect — pathogenic or benign — and list any associated condition.	Benign	TGAGGATGTGGAGCCCCTGCCAGACTGAATGGAATCGGGCCTCACCACCCACTCTCAACATGGCTGCAAAGCTGTGGAGGACCCCATCTGACCCACAGGGTGTGGCCTGTCCCCTGGGCCATGTGACCACCCCTCCCAGTCTGGTTCAGGACCAGTGGGGGAAGAACAGGGAATCAAGGCAAATCTGGGCACATCCCAGACGCCGAGGAGCAGGAAAGCAAAAGCAATAGGAAGCTCCCTTCTGAGACAGACAGCCACTCCCTGGGAGGGTTCAGCCCTCCTGCCTCCTGCATGGGCCCTGGGCATCCTCATCCTCTCTG...	TGAGGATGTGGAGCCCCTGCCAGACTGAATGGAATCGGGCCTCACCACCCACTCTCAACATGGCTGCAAAGCTGTGGAGGACCCCATCTGACCCACAGGGTGTGGCCTGTCCCCTGGGCCATGTGACCACCCCTCCCAGTCTGGTTCAGGACCAGTGGGGGAAGAACAGGGAATCAAGGCAAATCTGGGCACATCCCAGACGCCGAGGAGCAGGAAAGCAAAAGCAATAGGAAGCTCCCTTCTGAGACAGACAGCCACTCCCTGGGAGGGTTCAGCCCTCCTGCCTCCTGCATGGGCCCTGGGCATCCTCATCCTCTCTG...
Task1_train_35928	This variant is present on Chromosome 4. Is the change likely to result in a pathogenic outcome?	Benign	TGAATTTCCACCCTGGCATGTGGGAAAGCCTTCAGGAATCTTAAAGGGGTGCTTTAATGGAGGTGCCGATGTTAGGTATGGGGCTGGACTGCTTTTGTCCACACCACCCAGACACCCCACATGGGTCAGGCCAACTCCGGTTCCAGAGGGCGCCAGACACGCCACCCAGCTGACCCTTCTTGGGGAGGCGGAGGAGGGGCTGACATCACTCATTCACTCAGCAAAGCTCCCGAACGCCCATCCTGGGCCCAGCCCTGGGCTGGGTGCTGGGCCCCTGGACCTGAGCGAGGCCAGGCCCCATCCCAGGACACAGACATGGA...	TGAATTTCCACCCTGGCATGTGGGAAAGCCTTCAGGAATCTTAAAGGGGTGCTTTAATGGAGGTGCCGATGTTAGGTATGGGGCTGGACTGCTTTTGTCCACACCACCCAGACACCCCACATGGGTCAGGCCAACTCCGGTTCCAGAGGGCGCCAGACACGCCACCCAGCTGACCCTTCTTGGGGAGGCGGAGGAGGGGCTGACATCACTCATTCACTCAGCAAAGCTCCCGAACGCCCATCCTGGGCCCAGCCCTGGGCTGGGTGCTGGGCCCCTGGACCTGAGCGAGGCCAGGCCCCATCCCAGGACACAGACATGGA...
Task1_train_35929	Here is a mutation located on Chromosome 4. Determine whether it’s benign or pathogenic. If the latter, what disease does it cause?	Benign	CTATTTCTGTCTATATGGATTTACCTGTTCATACAATATGTGGTCCTTTTGCAACTCACTTCTTTCACTTCACATATTTTTCCCCCTTTTTATTGATTGATTGATTGATTGAGAGAGTCTCACTCTGTAATCTAGGCTGGAGTGCAGTGGCACAATCATGGCTCACTGCAGCCTCAACCTCCTCTGGGGCTCAAGTGATCCTCCCACCTCAGCCTCTTGAGTAGCTGGGATTACATGTGCATACCACCACACCCAGCTAATTTTTGTGTTTTGCAGAGATGGTGTTTCACCATGTTGCCCAGGCTGGTCTCAAACTCCTG...	CTATTTCTGTCTATATGGATTTACCTGTTCATACAATATGTGGTCCTTTTGCAACTCACTTCTTTCACTTCACATATTTTTCCCCCTTTTTATTGATTGATTGATTGATTGAGAGAGTCTCACTCTGTAATCTAGGCTGGAGTGCAGTGGCACAATCATGGCTCACTGCAGCCTCAACCTCCTCTGGGGCTCAAGTGATCCTCCCACCTCAGCCTCTTGAGTAGCTGGGATTACATGTGCATACCACCACACCCAGCTAATTTTTGTGTTTTGCAGAGATGGTGTTTCACCATGTTGCCCAGGCTGGTCTCAAACTCCTG...
Task1_train_35930	This variant is located on Chromosome 4. Evaluate its biological effect and specify any disease association.	Benign	CTCCCAAAATGCTGGGATCACAGGCATGAGCCACCATGCCTGGTTAGGCCAGAGAACTTTATTTTTTATTTTTTTATTTTTTGAAATGGAGCCTCGCCCTGTCGCCCAGGCTGGAGTGCAGTGGCATGATCTTGGCCCACTGCAACCTCCACCTCCTGGGTTCAAGTGATTTTCCTGCCTCAGCCTCCATGAGTAGCTGGGATTGTAGGCATGCACCACCACACCTGGCTAATTTTTTTTTTTTTTTTTTTTTGAGACAGAGTCTTGCTCTGTTGCCCAGGCTGGAGTGCAGTGGCATGATCTCGGCTCACTGCAACCTC...	CTCCCAAAATGCTGGGATCACAGGCATGAGCCACCATGCCTGGTTAGGCCAGAGAACTTTATTTTTTATTTTTTTATTTTTTGAAATGGAGCCTCGCCCTGTCGCCCAGGCTGGAGTGCAGTGGCATGATCTTGGCCCACTGCAACCTCCACCTCCTGGGTTCAAGTGATTTTCCTGCCTCAGCCTCCATGAGTAGCTGGGATTGTAGGCATGCACCACCACACCTGGCTAATTTTTTTTTTTTTTTTTTTTTGAGACAGAGTCTTGCTCTGTTGCCCAGGCTGGAGTGCAGTGGCATGATCTCGGCTCACTGCAACCTC...
Task1_train_35931	Given a variant located on Chromosome 4, assess whether it is benign or pathogenic. Indicate the associated disease if pathogenic.	Benign	AAGAAATTTGTGTTTCTAGCCAGTGCCCAGGCGATGCCGCTGCTGGTCCAGATTCCCCACTTGAGAACCACAGGGTTTGATCGTATTCATTAATTGGCCCCCTCCCCGAATCAAATGTTGGCTGCCCTGGGGCAGGGATTTTGTCAGTTTCATCCCCTCTGGTCCCCTGGGCCAGGCACAGACTAGGTGCTCAGGACCACTCTCTGCCAGGCCAGCTCTTGTACTTGATTGTCCAGGGTTTTTTAAATTGCAAAAGTAATATGTGCTTGTTTGGTTTTTTAAAACACAGTGCAGACATCTATGAAATAAAAGTAAAATTC...	AAGAAATTTGTGTTTCTAGCCAGTGCCCAGGCGATGCCGCTGCTGGTCCAGATTCCCCACTTGAGAACCACAGGGTTTGATCGTATTCATTAATTGGCCCCCTCCCCGAATCAAATGTTGGCTGCCCTGGGGCAGGGATTTTGTCAGTTTCATCCCCTCTGGTCCCCTGGGCCAGGCACAGACTAGGTGCTCAGGACCACTCTCTGCCAGGCCAGCTCTTGTACTTGATTGTCCAGGGTTTTTTAAATTGCAAAAGTAATATGTGCTTGTTTGGTTTTTTAAAACACAGTGCAGACATCTATGAAATAAAAGTAAAATTC...
Task1_train_35932	This variant is present on Chromosome 4. Is the change likely to result in a pathogenic outcome?	Benign	TGGGACTACAGGCGCCCGCCACCAGGTCTGGCTAATTTTTTGTATTTTTAGTAGAGATGGGGTTTCACCGTGTTAGCCAGGATGGTCTCGATCTCCTGACCTCACGATCTGCCCACCTCGGCCTCCCAAAATGCTGGGATTATAGAGGTGAGCCACCTAGCCCGGCCCAAAATCACTTAAATTTAAGATTAATCTAAGGGGATTAGTGAGCTTCTAACTGAAACAGTGTCTCGGGACTACATAATTTAATAAATCCAAAGAATTTAATAATTAGCTTAATGCACAGGGTTTTTTTGTACCTTGCCCATTCGCTGAACTTT...	TGGGACTACAGGCGCCCGCCACCAGGTCTGGCTAATTTTTTGTATTTTTAGTAGAGATGGGGTTTCACCGTGTTAGCCAGGATGGTCTCGATCTCCTGACCTCACGATCTGCCCACCTCGGCCTCCCAAAATGCTGGGATTATAGAGGTGAGCCACCTAGCCCGGCCCAAAATCACTTAAATTTAAGATTAATCTAAGGGGATTAGTGAGCTTCTAACTGAAACAGTGTCTCGGGACTACATAATTTAATAAATCCAAAGAATTTAATAATTAGCTTAATGCACAGGGTTTTTTTGTACCTTGCCCATTCGCTGAACTTT...
Task1_train_35933	Given this context: Chromosome 4 — does this variant present pathogenic behavior, and if so, what disease does it relate to?	Benign	ACACCCCACCCTGACCACCCACTGCAGGTAGCTCTGGGGTGGGGGCAGGTGGGCTGAGCTGGGCCACCTGGCAGGTGTGGCGCTTGCCCTCTCCCGGCCTCTCCCAGGTGACCTGTCGGGGGATTTCAGGTCATGTCACACATACTTCCCGGTAGGCATCCTCCCGACTCACAGCCAAGCCAGAGGAGGGCCTATGGCTCCATCCTGTCCCAGAGAGTGTGTCAGGTGGGAACACCTACCGGCAGGCAGACAGAGAGCCTCTGGGGCTGCTCCTGGAGAGGGTGGGTGGTCTCAGGGGAAGAGGCAGATACTGAGGCCAA...	ACACCCCACCCTGACCACCCACTGCAGGTAGCTCTGGGGTGGGGGCAGGTGGGCTGAGCTGGGCCACCTGGCAGGTGTGGCGCTTGCCCTCTCCCGGCCTCTCCCAGGTGACCTGTCGGGGGATTTCAGGTCATGTCACACATACTTCCCGGTAGGCATCCTCCCGACTCACAGCCAAGCCAGAGGAGGGCCTATGGCTCCATCCTGTCCCAGAGAGTGTGTCAGGTGGGAACACCTACCGGCAGGCAGACAGAGAGCCTCTGGGGCTGCTCCTGGAGAGGGTGGGTGGTCTCAGGGGAAGAGGCAGATACTGAGGCCAA...
Task1_train_35934	A sequence alteration has been identified on Chromosome 4. Is it disease-inducing or harmless?	Benign	CTGCCCAGCGGGCCCAGGCCTGCCCAGCCAATAGGGGCCACTTCTGAGGCATCCAGAATCTCAGGCCCAGTGTGCCTGTGTTCCTGGGGCGGTGGCCCAGGTCTGCGACGTTTACTTAAGAGCTCGGGTGTGGCCTCTTGGAAAACAGCACCCGCTCACATCCCGTCCATCCAGGCCTGGCGCACCTCTTACTCAAGAGGAGAATTAATCCATGGGCCTCAGGTGAAATACCAGCTTCCACCCCCGGGACTCATGTGTGCGGCTCCCAGATGTGTGAGCACCTGCTGCGTGCAGATGCTGGGCCAGCTGCAAGGACACTG...	CTGCCCAGCGGGCCCAGGCCTGCCCAGCCAATAGGGGCCACTTCTGAGGCATCCAGAATCTCAGGCCCAGTGTGCCTGTGTTCCTGGGGCGGTGGCCCAGGTCTGCGACGTTTACTTAAGAGCTCGGGTGTGGCCTCTTGGAAAACAGCACCCGCTCACATCCCGTCCATCCAGGCCTGGCGCACCTCTTACTCAAGAGGAGAATTAATCCATGGGCCTCAGGTGAAATACCAGCTTCCACCCCCGGGACTCATGTGTGCGGCTCCCAGATGTGTGAGCACCTGCTGCGTGCAGATGCTGGGCCAGCTGCAAGGACACTG...
Task1_train_35935	This mutation on Chromosome 4 may be significant. Is it associated with any clinical condition, or is it benign?	Benign	TTCCACCCCCGGGACTCATGTGTGCGGCTCCCAGATGTGTGAGCACCTGCTGCGTGCAGATGCTGGGCCAGCTGCAAGGACACTGCAGGGTCATGCCCAGGGGCTCTCCTGGAGGGGGCACAGTGTCTTAGGGGGGCCAAACAGCAGGAGCAGAAACCACAGGAGCACTTGAACCCAGATGGAAACCCCCCCCGGAGGCTTTCTGCCAGAGGGGGCACCGGGGCGAGGTGGAGGCACCAGGGTAAGGTGGAGGCTGTTGTAGCAGCTCTGGGATCTGCGCCTTCCCTGAGAATAAAAACACGGCACACGGCATTTGGAGA...	TTCCACCCCCGGGACTCATGTGTGCGGCTCCCAGATGTGTGAGCACCTGCTGCGTGCAGATGCTGGGCCAGCTGCAAGGACACTGCAGGGTCATGCCCAGGGGCTCTCCTGGAGGGGGCACAGTGTCTTAGGGGGGCCAAACAGCAGGAGCAGAAACCACAGGAGCACTTGAACCCAGATGGAAACCCCCCCCGGAGGCTTTCTGCCAGAGGGGGCACCGGGGCGAGGTGGAGGCACCAGGGTAAGGTGGAGGCTGTTGTAGCAGCTCTGGGATCTGCGCCTTCCCTGAGAATAAAAACACGGCACACGGCATTTGGAGA...
Task1_train_35936	This mutation occurs on Chromosome 4. Does this change lead to a known medical condition, or is it benign?	Benign	AGGCTCAGACAGCTGGAGGGCTGTGTTCACCGTCTTTGCCCTCGCTGCTCCACATCCCGGTGGCCACCCCAGACTCCTCCGGCTTTTCCCGGGAGCTTTTGCCTGGCATATTTTGCTCTCCTGACTTTGAGCACACCCCAAGACTTTCCTTCTGCTCATTACCAGGGCAGCGGAGGGTCTGGGGTGCAAGGAGAGAGAGGGACCCTGTAGTGGCTGAGACATGGGGGGGGACTGCTCCGAAGCCCAGCAGCCCTTGGAGAATGTGACCAAAGCCCCAGACCTCTCCCCGGAAATGTCCAGGGATACGTGCTTGTCATACA...	AGGCTCAGACAGCTGGAGGGCTGTGTTCACCGTCTTTGCCCTCGCTGCTCCACATCCCGGTGGCCACCCCAGACTCCTCCGGCTTTTCCCGGGAGCTTTTGCCTGGCATATTTTGCTCTCCTGACTTTGAGCACACCCCAAGACTTTCCTTCTGCTCATTACCAGGGCAGCGGAGGGTCTGGGGTGCAAGGAGAGAGAGGGACCCTGTAGTGGCTGAGACATGGGGGGGGACTGCTCCGAAGCCCAGCAGCCCTTGGAGAATGTGACCAAAGCCCCAGACCTCTCCCCGGAAATGTCCAGGGATACGTGCTTGTCATACA...
Task1_train_35937	Here’s a variant located on Chromosome 4. What is the predicted biological effect — harmless or disease-causing?	Benign	CTCCTCCGGCTTTTCCCGGGAGCTTTTGCCTGGCATATTTTGCTCTCCTGACTTTGAGCACACCCCAAGACTTTCCTTCTGCTCATTACCAGGGCAGCGGAGGGTCTGGGGTGCAAGGAGAGAGAGGGACCCTGTAGTGGCTGAGACATGGGGGGGGACTGCTCCGAAGCCCAGCAGCCCTTGGAGAATGTGACCAAAGCCCCAGACCTCTCCCCGGAAATGTCCAGGGATACGTGCTTGTCATACACACCTTTGGCAGCCACCCCCAGGGACTCCAGGTTGAGAAGCTCTGGCCTGAGCGAGACCCAGACTCCCACCCC...	CTCCTCCGGCTTTTCCCGGGAGCTTTTGCCTGGCATATTTTGCTCTCCTGACTTTGAGCACACCCCAAGACTTTCCTTCTGCTCATTACCAGGGCAGCGGAGGGTCTGGGGTGCAAGGAGAGAGAGGGACCCTGTAGTGGCTGAGACATGGGGGGGGACTGCTCCGAAGCCCAGCAGCCCTTGGAGAATGTGACCAAAGCCCCAGACCTCTCCCCGGAAATGTCCAGGGATACGTGCTTGTCATACACACCTTTGGCAGCCACCCCCAGGGACTCCAGGTTGAGAAGCTCTGGCCTGAGCGAGACCCAGACTCCCACCCC...
Task1_train_35938	A genomic change on Chromosome 4 is noted. Classify this variant as benign or pathogenic, and name the disease if relevant.	Benign	CAGCCCTTGGAGAATGTGACCAAAGCCCCAGACCTCTCCCCGGAAATGTCCAGGGATACGTGCTTGTCATACACACCTTTGGCAGCCACCCCCAGGGACTCCAGGTTGAGAAGCTCTGGCCTGAGCGAGACCCAGACTCCCACCCCCGGCTGTTGGCAAGAGGTAATGACCCTACTAGTGATGGGCCCTCGAAGCCTCCGTCCACCCCTGCCTCCGCTCACCCCGGCCATGACCCCAGCCTGGCTCACAGCCAGATGTCCATCCAGCAGAAGGTAAAGGGGCACCTGAGCCCATGGGCAGGCTCTCATGGGACCACCGGC...	CAGCCCTTGGAGAATGTGACCAAAGCCCCAGACCTCTCCCCGGAAATGTCCAGGGATACGTGCTTGTCATACACACCTTTGGCAGCCACCCCCAGGGACTCCAGGTTGAGAAGCTCTGGCCTGAGCGAGACCCAGACTCCCACCCCCGGCTGTTGGCAAGAGGTAATGACCCTACTAGTGATGGGCCCTCGAAGCCTCCGTCCACCCCTGCCTCCGCTCACCCCGGCCATGACCCCAGCCTGGCTCACAGCCAGATGTCCATCCAGCAGAAGGTAAAGGGGCACCTGAGCCCATGGGCAGGCTCTCATGGGACCACCGGC...
Task1_train_35939	A genomic variant on Chromosome 4 is under review. What is the biological outcome — benign or pathogenic?	Benign	CTGGCTCACGGCATTGCAACTCTATTGGCTGGCTCACGGCATTTCACCACTGATGAGGTCAGGCTTCTTGCTTACATTGGAAGGCTGTAGATGTTTATGTGTCACTTGTAAGTGAAGTCACTTTTCAGCTGTAAAAATAGTTGTACACGAAGTGATACTGGGTAAATTTCCAATTCTTGCTGTCGTGTCATTCAGGAAACTGCGTCTACTCACTTCAGCTCTCTCAAGGAATAAGCACCTTCCTCAGTGGTCCAAGCGTTTGTGAAGGTATGAAATGCTACCACTTTCTCTCCAGGACTCGGGGCACACAGCTACTGTGC...	CTGGCTCACGGCATTGCAACTCTATTGGCTGGCTCACGGCATTTCACCACTGATGAGGTCAGGCTTCTTGCTTACATTGGAAGGCTGTAGATGTTTATGTGTCACTTGTAAGTGAAGTCACTTTTCAGCTGTAAAAATAGTTGTACACGAAGTGATACTGGGTAAATTTCCAATTCTTGCTGTCGTGTCATTCAGGAAACTGCGTCTACTCACTTCAGCTCTCTCAAGGAATAAGCACCTTCCTCAGTGGTCCAAGCGTTTGTGAAGGTATGAAATGCTACCACTTTCTCTCCAGGACTCGGGGCACACAGCTACTGTGC...