Split (2)

train · 48.9k rows

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ID stringlengths 13 17	question stringlengths 88 1.13k	answer stringlengths 6 156	reference_sequence stringlengths 4.1k 4.1k	variant_sequence stringlengths 4.1k 4.1k
Task1_train_39900	Assess the clinical impact of this variant found on Chromosome 10. State whether it’s pathogenic or benign, and the disease if applicable.	Benign	CAGGAGATCGAGACCATCCTGCCTAACACGGTGAAACCCCATCTGTACTAAAAATACAAAAAAATCAGCCAGGTGTGGTGGTGGGCACCTGTAGTCCTAGCTACTTGGGAGGCTGAGGCAGGAGAATGGTATGAACTCGGGAGGCGGAGCTTGCAGAGAGCCGAGATTGTGCCACTGCACTCCAGCCTGGGCGACAGAGCGAGACTCCATCTCAAAAAAAAAAAAAAAAAGAAAAAAAAAAAGAAAGAAATACTGATAGGACAATGCTCAATAAGTTGACATATTTCAAAATATTAAGGTTTTTTAAGTTTTAATGACAC...	CAGGAGATCGAGACCATCCTGCCTAACACGGTGAAACCCCATCTGTACTAAAAATACAAAAAAATCAGCCAGGTGTGGTGGTGGGCACCTGTAGTCCTAGCTACTTGGGAGGCTGAGGCAGGAGAATGGTATGAACTCGGGAGGCGGAGCTTGCAGAGAGCCGAGATTGTGCCACTGCACTCCAGCCTGGGCGACAGAGCGAGACTCCATCTCAAAAAAAAAAAAAAAAAGAAAAAAAAAAAGAAAGAAATACTGATAGGACAATGCTCAATAAGTTGACATATTTCAAAATATTAAGGTTTTTTAAGTTTTAATGACAC...
Task1_train_39901	Mutation context: Chromosome 10. Determine if this variant is likely to be benign or pathogenic. Mention the disease if applicable.	Benign	AATAAACATGCACTGTGGGAATCACTCATAAGATGATTTACAGTAAAATTTGTGGATGGAAAAATAGGAACCAGGATGGTTGCCTACCAACAGTACTTAATAAATGTGCTTTGGGGCTTCAAAGGGAGGAATTAGGAAGAAAGAAGGGAAAATAACAAGAAGAGAAAAGCTTTAATGAGAGAAAGTGGACAGGTATCCTAAAGGAGTCCATATTTCCACAGAAGGAAAGAAGAATTAATGACAACAAAATAGCCAAAACTTGTAGGGCTCACCATGTTCAAAGCACTTAGTAAATCTCCTACCTTTGGTTTTAAAATCTC...	AATAAACATGCACTGTGGGAATCACTCATAAGATGATTTACAGTAAAATTTGTGGATGGAAAAATAGGAACCAGGATGGTTGCCTACCAACAGTACTTAATAAATGTGCTTTGGGGCTTCAAAGGGAGGAATTAGGAAGAAAGAAGGGAAAATAACAAGAAGAGAAAAGCTTTAATGAGAGAAAGTGGACAGGTATCCTAAAGGAGTCCATATTTCCACAGAAGGAAAGAAGAATTAATGACAACAAAATAGCCAAAACTTGTAGGGCTCACCATGTTCAAAGCACTTAGTAAATCTCCTACCTTTGGTTTTAAAATCTC...
Task1_train_39902	A variant on Chromosome 10 is under investigation. Evaluate whether it is clinically benign or pathogenic and name the disorder if relevant.	Benign	GATAGGCTGGATAAAGAAAATGTGGCACCTATACACCATGGAATACTTTGTAGCCATAAAAAAGGATGAGTTCATGTACTTTGAAGGGACATGGATGAAGCTGGAAACCATCATTCTCAGCAAACTAACACAGGAACAAAAAACCAAACACCGCATATTCTCACTCGTAAGTGGGAGTTGAACAATGAGAACGCATGGACACAGGGAGGGGAACATCACACACCGGTGCCTGTCGAGGGGTGGGGGGCTAAGGGAGGGATAGCATTAGGAGAAATACCTTATGTAGATGACGGGTTGATGAGTGCAGCAAACCACCATGG...	GATAGGCTGGATAAAGAAAATGTGGCACCTATACACCATGGAATACTTTGTAGCCATAAAAAAGGATGAGTTCATGTACTTTGAAGGGACATGGATGAAGCTGGAAACCATCATTCTCAGCAAACTAACACAGGAACAAAAAACCAAACACCGCATATTCTCACTCGTAAGTGGGAGTTGAACAATGAGAACGCATGGACACAGGGAGGGGAACATCACACACCGGTGCCTGTCGAGGGGTGGGGGGCTAAGGGAGGGATAGCATTAGGAGAAATACCTTATGTAGATGACGGGTTGATGAGTGCAGCAAACCACCATGG...
Task1_train_39903	A variant found on Chromosome 10 is being studied. Please analyze its biological impact: is it benign or pathogenic, and what condition might it cause?	Benign	CTGGCTACAAAACATTCCACCATTCTGGTTTATGAAATTAAAACTTCCAAAGCCAGTTTTATGATTTTTTGTGCAAACTTTTCAGAAGAATTCAGAGGAGTTCATGGAACCGCTCACTGAAATTCAGTTCTAGTGTTCTGCAAAGCCTGAGAGGATGAACCATTCAGAGGTACTGATAGTTCTTTAGAACCAGAGAATCACCATGAAGGCTTTAACAGAAAGGGCCCCAAATTTCCCTGAAAATTATAGTTACATTCTTGCGTATCTGAGAAAATCATGATGCTCGGCTTCATGTTTTAGTCTCGTGATCGGAGAGCCAG...	CTGGCTACAAAACATTCCACCATTCTGGTTTATGAAATTAAAACTTCCAAAGCCAGTTTTATGATTTTTTGTGCAAACTTTTCAGAAGAATTCAGAGGAGTTCATGGAACCGCTCACTGAAATTCAGTTCTAGTGTTCTGCAAAGCCTGAGAGGATGAACCATTCAGAGGTACTGATAGTTCTTTAGAACCAGAGAATCACCATGAAGGCTTTAACAGAAAGGGCCCCAAATTTCCCTGAAAATTATAGTTACATTCTTGCGTATCTGAGAAAATCATGATGCTCGGCTTCATGTTTTAGTCTCGTGATCGGAGAGCCAG...
Task1_train_39904	A mutation on Chromosome 10 is under examination. Does this mutation cause a disorder, or is it a benign change?	Benign	TGTTTTCACTGATTCCCATTCTCTGTGTCCCTGTGACACCCAATTTCACCCCACACAACATAGCTCATGTCTTTAACTCTTGTATCTGTTCTCCCATTGGGGTTGGTCTTGTCTCCTCAGCTGCAAGGTGAGCAGTTCATAAGTGGAGACAGTATTTTACACTTTCATATTTTTCCATAGGGTCTACTATTGTCCTAAACATATAACAACAACCTCTCAATAAATGTGTTGATTCCAAATCAGGAGTTTAAGTGAGGGGCAGAAGAGTCAAAAGTGACTTTATGGAAGAAGTTGAGAGGGAAGTGCTCCTGAGGGACAGA...	TGTTTTCACTGATTCCCATTCTCTGTGTCCCTGTGACACCCAATTTCACCCCACACAACATAGCTCATGTCTTTAACTCTTGTATCTGTTCTCCCATTGGGGTTGGTCTTGTCTCCTCAGCTGCAAGGTGAGCAGTTCATAAGTGGAGACAGTATTTTACACTTTCATATTTTTCCATAGGGTCTACTATTGTCCTAAACATATAACAACAACCTCTCAATAAATGTGTTGATTCCAAATCAGGAGTTTAAGTGAGGGGCAGAAGAGTCAAAAGTGACTTTATGGAAGAAGTTGAGAGGGAAGTGCTCCTGAGGGACAGA...
Task1_train_39905	A variant was discovered on Chromosome 10. What is its functional impact — neutral or pathogenic? State the disease if pathogenic.	Benign	CATTGTATTCAATGGTTGTAGATTTATAATTCAAATTATTAAAATTATAAGAATTCTTAAAAACCTTTAAAGATTTAAAAATATTCATATTCTTTGATTTAAGTAGAATCCTCTTCTAAGACTCTGCCTAAGAAAATTATCATATTTGTGCATGGCAAAATGTGTACATGAAAAAAAGTTGGAAGAAAAAAACGCCCAAATGTTCATCATGGTCCTCTGTGTGATAAGATCAAAGGTATTTTTTTCTATTTTTTCCATATTTTTGTAGTGATATTTTATAAGCAGCATATATTGCTTTGCTGCTTATAAAATATAACTAC...	CATTGTATTCAATGGTTGTAGATTTATAATTCAAATTATTAAAATTATAAGAATTCTTAAAAACCTTTAAAGATTTAAAAATATTCATATTCTTTGATTTAAGTAGAATCCTCTTCTAAGACTCTGCCTAAGAAAATTATCATATTTGTGCATGGCAAAATGTGTACATGAAAAAAAGTTGGAAGAAAAAAACGCCCAAATGTTCATCATGGTCCTCTGTGTGATAAGATCAAAGGTATTTTTTTCTATTTTTTCCATATTTTTGTAGTGATATTTTATAAGCAGCATATATTGCTTTGCTGCTTATAAAATATAACTAC...
Task1_train_39906	This sequence change occurs on Chromosome 10. What is the medical significance of this variant — is it benign or linked to a disease?	Benign	ATGCACTAAATTCTTTGGGAAGGAAGACCCATAATCTAAACTATTTTCAGTTTACCTATAATATTATCCAAAATAAAGCCATTCTGCTTATCGAATCAAATTTCCTTTGGGAAAAAAAGCCTTTAAATTATAATTTATATAAGCATTTATAACTGTGATACCTACAGAGGTTGGAGATAATAGAAACTCTTGGTACTGAAAGCCACAATTTTCTATTGTTTGTATCAAGAGGTCTCTAAAAAGAAAAAAAAAAAACTTTAATTCTTACTTGGAAAGGCAGTTCTTATTTAAATAATGTACACAAAAGCTGGGTTTCTTTT...	ATGCACTAAATTCTTTGGGAAGGAAGACCCATAATCTAAACTATTTTCAGTTTACCTATAATATTATCCAAAATAAAGCCATTCTGCTTATCGAATCAAATTTCCTTTGGGAAAAAAAGCCTTTAAATTATAATTTATATAAGCATTTATAACTGTGATACCTACAGAGGTTGGAGATAATAGAAACTCTTGGTACTGAAAGCCACAATTTTCTATTGTTTGTATCAAGAGGTCTCTAAAAAGAAAAAAAAAAAACTTTAATTCTTACTTGGAAAGGCAGTTCTTATTTAAATAATGTACACAAAAGCTGGGTTTCTTTT...
Task1_train_39907	An alteration has been detected on Chromosome 10. Is it pathogenic, and if so, what disease is involved?	Benign	AATGAGTAAAAATTATATTTCACAGTGAAGACAAAATAAAACACTTTTTTACTCAAAAGCACCAAGGTAATTTGTCCCTTTCCACATATAACCAACAAGAGACACTAAAGAAGGTTTTTCAGGAAGAAGAAAAATTATATCACATGCAAACTTTGATCTAAAACACAAGGATAAAAAGTGCTGAAAATTGTAGGTATATAGATAAATATAAAAGACTTTGTGCTTTTTAAAAGTTCTTTAATAGATATTTGACTATTTAATCCAAAAAACAGTAACAATGTATGTTGGTGCCTATAACATTCGTAGCAGTAAAGTGCAAG...	AATGAGTAAAAATTATATTTCACAGTGAAGACAAAATAAAACACTTTTTTACTCAAAAGCACCAAGGTAATTTGTCCCTTTCCACATATAACCAACAAGAGACACTAAAGAAGGTTTTTCAGGAAGAAGAAAAATTATATCACATGCAAACTTTGATCTAAAACACAAGGATAAAAAGTGCTGAAAATTGTAGGTATATAGATAAATATAAAAGACTTTGTGCTTTTTAAAAGTTCTTTAATAGATATTTGACTATTTAATCCAAAAAACAGTAACAATGTATGTTGGTGCCTATAACATTCGTAGCAGTAAAGTGCAAG...
Task1_train_39908	Given a variant located on Chromosome 10, assess whether it is benign or pathogenic. Indicate the associated disease if pathogenic.	Benign	TGGTGGTCTCTTCACATGGACACGCCTAACAGAGATGGTATAAAAATGCTTTGAAAACCTAAGAAAAACATTCATTTAATTATTTGTTTATTCAACAAAAATTAATTGAGCAACTGCTATGTGCTGCACCCTTGTGATTGGCACCAGGGGATAGGCATGTGAACAAGACATTGTCCCATTCATTTTGGAGCTCAAAATCTGAAACACAGAATAAAGAATTATGGCACAAAAGACCCTATCCCACTTGTTCTCCTAATGGCAACTGCCTAATTTTCATTTATTCAAAAAATATAGTTAAGACTAGGGGAGAAAAAGAGCAC...	TGGTGGTCTCTTCACATGGACACGCCTAACAGAGATGGTATAAAAATGCTTTGAAAACCTAAGAAAAACATTCATTTAATTATTTGTTTATTCAACAAAAATTAATTGAGCAACTGCTATGTGCTGCACCCTTGTGATTGGCACCAGGGGATAGGCATGTGAACAAGACATTGTCCCATTCATTTTGGAGCTCAAAATCTGAAACACAGAATAAAGAATTATGGCACAAAAGACCCTATCCCACTTGTTCTCCTAATGGCAACTGCCTAATTTTCATTTATTCAAAAAATATAGTTAAGACTAGGGGAGAAAAAGAGCAC...
Task1_train_39909	This alteration on Chromosome 10 may affect genome function. Does it lead to a disease or is it benign?	Benign	GTGAGCCACCACACCAGGCCACAAGCTAGTGATTTTTAAGCAACTCACTTAACCTCTTTCATCTTAATGTAAATGAGAAATAATACTACTACTTTTGAATACTAAGTACTCAAAAAGTACTTTTAATTAGCAAAGGATTTAATAAGTAAAATTAATTGATTTATTACTAACATTAAGAATGCAGGGGGAGGAGGGAATTAAAAAAAAATGCAGTGGAAAACATGTTCTGGGCTGAGTGATTCTCTGGCCAGTGGGACTCAGTAGCTGGCAGCATGGTGAACTGGGAAGCTGCTACTGGTACAGGCCAGAGTCTACATCTC...	GTGAGCCACCACACCAGGCCACAAGCTAGTGATTTTTAAGCAACTCACTTAACCTCTTTCATCTTAATGTAAATGAGAAATAATACTACTACTTTTGAATACTAAGTACTCAAAAAGTACTTTTAATTAGCAAAGGATTTAATAAGTAAAATTAATTGATTTATTACTAACATTAAGAATGCAGGGGGAGGAGGGAATTAAAAAAAAATGCAGTGGAAAACATGTTCTGGGCTGAGTGATTCTCTGGCCAGTGGGACTCAGTAGCTGGCAGCATGGTGAACTGGGAAGCTGCTACTGGTACAGGCCAGAGTCTACATCTC...
Task1_train_39910	A genomic change on Chromosome 10 is noted. Classify this variant as benign or pathogenic, and name the disease if relevant.	Benign	TGTTAGTTGGGGAAGGTGTCACTGATGACGGTTTTCTAAAGCTACCTGTAGCGATGGTAGTATTATAAGGTGATAATAAGTGACAATTACTGTTAGTATTTTGAGACCACTGAAGCTTATGTATTTATTTGTCTCTGATTTTAGTTTACTACAGTCAGCATGTGCCAGGCACTGTGTTAGACACCTGAGAGTCTTCTTTAGCTTCAAGGTGCTTACTGAGTAGTAGGGGCAAACACATAAAAAAATATAATTTTATACAACATGATTTATAAATAAAGAAGATATATGCCTTGTACCTTAGGAGCCTCAGGGTTTGAGGA...	TGTTAGTTGGGGAAGGTGTCACTGATGACGGTTTTCTAAAGCTACCTGTAGCGATGGTAGTATTATAAGGTGATAATAAGTGACAATTACTGTTAGTATTTTGAGACCACTGAAGCTTATGTATTTATTTGTCTCTGATTTTAGTTTACTACAGTCAGCATGTGCCAGGCACTGTGTTAGACACCTGAGAGTCTTCTTTAGCTTCAAGGTGCTTACTGAGTAGTAGGGGCAAACACATAAAAAAATATAATTTTATACAACATGATTTATAAATAAAGAAGATATATGCCTTGTACCTTAGGAGCCTCAGGGTTTGAGGA...
Task1_train_39911	An alteration has been detected on Chromosome 10. Is it pathogenic, and if so, what disease is involved?	Benign	CTCAATTCACACTTAAACTTTAAAACTAATTAGTTACTTGTATAAAAGAAATTAGAAATGTATTGTGTCCTTTAAACAAACTCCTACTTACAGTAGGTAAGCATTTTATTAGTTATTCATAATAATTTATTTATTTTAAAATGTTTTCAAATTCAGTTCCACGCGCTTCAACAAATTTTTATTGACTTTGTCTCTTTGACCTTTAGAGCTATTCAGTCTAATGGCTCCTTTTAAGTTTTGTTTTATCACGTCATATGGCAGCTCAGCATGTTTGCTGAGTAAACTTTGTCAAGTCCTGATAATTTCTTAGCAACCAAAAT...	CTCAATTCACACTTAAACTTTAAAACTAATTAGTTACTTGTATAAAAGAAATTAGAAATGTATTGTGTCCTTTAAACAAACTCCTACTTACAGTAGGTAAGCATTTTATTAGTTATTCATAATAATTTATTTATTTTAAAATGTTTTCAAATTCAGTTCCACGCGCTTCAACAAATTTTTATTGACTTTGTCTCTTTGACCTTTAGAGCTATTCAGTCTAATGGCTCCTTTTAAGTTTTGTTTTATCACGTCATATGGCAGCTCAGCATGTTTGCTGAGTAAACTTTGTCAAGTCCTGATAATTTCTTAGCAACCAAAAT...
Task1_train_39912	This genomic variant is located on Chromosome 10. Can you determine its pathogenicity and name any linked disease?	Benign	TGGCTTAGCAGCCACTTAACCGCATGTGGCCACTGAGCACATGAGCTGTGGCTAGAGGAACAAATCATCTTCTGTGGCTGCCCCAGGGAACTCCCCTTCATTTCACTCAAGTTGGTTGTTTTCATGCTTTCAAATATGTTTAAAGTTCATCATTTCAGTTTTTGAAGGACAGCATTGGCTGATACTATTTTCAATTTCCTAGGTAGCAAAATTAAAATAACCCACCAGAGGGCTCCAAAGCTGTACTAAGCTTGCTTTCTTTTTCTTTTTCTTCTTTTTTTTTTTGTAACCACTGGAAGTGCACAGAATCTAAATTGTAT...	TGGCTTAGCAGCCACTTAACCGCATGTGGCCACTGAGCACATGAGCTGTGGCTAGAGGAACAAATCATCTTCTGTGGCTGCCCCAGGGAACTCCCCTTCATTTCACTCAAGTTGGTTGTTTTCATGCTTTCAAATATGTTTAAAGTTCATCATTTCAGTTTTTGAAGGACAGCATTGGCTGATACTATTTTCAATTTCCTAGGTAGCAAAATTAAAATAACCCACCAGAGGGCTCCAAAGCTGTACTAAGCTTGCTTTCTTTTTCTTTTTCTTCTTTTTTTTTTTGTAACCACTGGAAGTGCACAGAATCTAAATTGTAT...
Task1_train_39913	This sequence variant lies on Chromosome 10. Is it clinically significant, and what condition might it cause if any?	Benign	GTTGAGAGGTTTTGTTTTGAGGAGCATGAAGGATCTGATGTAAGAACTACCACCGGTGCTGGTGATCACAATATATGCAGCTGATTAAAGTTCCTCATTTATGCTACCTACATCCCTGGTAAGAATTTCATTCCTTCAACCAATACTTTTCATTTGAAAGCATCTCATTACGAAAGACTTCAATCTTTTAGGCTTCTGCATCTTGCAAAACAAATATGGTTCCAAAGAGCCTATCTTTTCAACAAATCTTTGGTTTGAGCCTGGATGAAACAGTTATTACAGAATCAACTGGAGAGGAAAAAATCTTCATCTAACACTGA...	GTTGAGAGGTTTTGTTTTGAGGAGCATGAAGGATCTGATGTAAGAACTACCACCGGTGCTGGTGATCACAATATATGCAGCTGATTAAAGTTCCTCATTTATGCTACCTACATCCCTGGTAAGAATTTCATTCCTTCAACCAATACTTTTCATTTGAAAGCATCTCATTACGAAAGACTTCAATCTTTTAGGCTTCTGCATCTTGCAAAACAAATATGGTTCCAAAGAGCCTATCTTTTCAACAAATCTTTGGTTTGAGCCTGGATGAAACAGTTATTACAGAATCAACTGGAGAGGAAAAAATCTTCATCTAACACTGA...
Task1_train_39914	A genomic variant on Chromosome 10 is under review. What is the biological outcome — benign or pathogenic?	Benign	CTCTCTGCACCACACTGCTGCTACTGGGGAGGTGGGAGAGGGGTGACATCAGAGATTCAAGACTGTTTTTTCTGCCTCTTCAGTGCCTATTTCAGTAATATGAAGTTAAAACCAGGTATAACGAGGGCTCACCTGAATTTTAGTTTGTATGAAGGTGCTTTTCTTGTGTAGATAGTTGTTAAATTGGTGTCCTTGTGGGGAGATGATTGGTGGAGGCTTCTATTCTGCCATCTTACTCTGCCTCCTCCAGTTTTTTTCTGTAGCTCTTTGAATATATCATTTCACTACCCTTCTGTCCCCCATTATTTAGATAAGAAATC...	CTCTCTGCACCACACTGCTGCTACTGGGGAGGTGGGAGAGGGGTGACATCAGAGATTCAAGACTGTTTTTTCTGCCTCTTCAGTGCCTATTTCAGTAATATGAAGTTAAAACCAGGTATAACGAGGGCTCACCTGAATTTTAGTTTGTATGAAGGTGCTTTTCTTGTGTAGATAGTTGTTAAATTGGTGTCCTTGTGGGGAGATGATTGGTGGAGGCTTCTATTCTGCCATCTTACTCTGCCTCCTCCAGTTTTTTTCTGTAGCTCTTTGAATATATCATTTCACTACCCTTCTGTCCCCCATTATTTAGATAAGAAATC...
Task1_train_39915	A variant on Chromosome 10 is under investigation. Evaluate whether it is clinically benign or pathogenic and name the disorder if relevant.	Benign	TCTCTTCCCTCTGAAATCTCTTACCAGGGATAATGATGGTGGACCAATGATCCCCACTCCAGCAAAGCCTGAGCTGGTTAAAATTTTCCACAAGCCTCTGGCAGTTTCCTGCAGGGTCACTCTTGTTGCTTCGAGGCTCAATTGTTATTCAATGTTCTGAAAATCACAAAGGGAGCATTGGAAAAATAAAACCATTATGAGTTTTAATTGCCCTCATAATCTAATATCCTGGAAATATTTCAGGGCTTATGACTGAGTAGAGGCGGCGGCCCAGGCCTTTTTTCTAGGTCACAGCAGCGGTAGCAGAATTGTTTACTGCC...	TCTCTTCCCTCTGAAATCTCTTACCAGGGATAATGATGGTGGACCAATGATCCCCACTCCAGCAAAGCCTGAGCTGGTTAAAATTTTCCACAAGCCTCTGGCAGTTTCCTGCAGGGTCACTCTTGTTGCTTCGAGGCTCAATTGTTATTCAATGTTCTGAAAATCACAAAGGGAGCATTGGAAAAATAAAACCATTATGAGTTTTAATTGCCCTCATAATCTAATATCCTGGAAATATTTCAGGGCTTATGACTGAGTAGAGGCGGCGGCCCAGGCCTTTTTTCTAGGTCACAGCAGCGGTAGCAGAATTGTTTACTGCC...
Task1_train_39916	Given a variant located on Chromosome 10, assess whether it is benign or pathogenic. Indicate the associated disease if pathogenic.	Benign	AAAAGCCAGGATAAAGACTAGTAATTTGGCTTCTAGAGCCAATACCTTGTCCTTGACCATAGCATATTTCTTCAATAAATCCATGAGATTCTTTCATGGCTAAAACATCTGAAAGTGATAAATGTCTAAATCAGACATTTCCAAAGGAATTTCTGTAGCCTGAATTTCATGGTGACCATAGCACCACTGATGGCTAGAATCTGTATTTTAGCGATAAAGGAGGAGAAACAAGTTGAACTACATTTTAAACTCCACAAGGATAGAGACTTTATCACACCACTATGTACCCAAGCCTAATCCATAATGGGCACTCAAATACT...	AAAAGCCAGGATAAAGACTAGTAATTTGGCTTCTAGAGCCAATACCTTGTCCTTGACCATAGCATATTTCTTCAATAAATCCATGAGATTCTTTCATGGCTAAAACATCTGAAAGTGATAAATGTCTAAATCAGACATTTCCAAAGGAATTTCTGTAGCCTGAATTTCATGGTGACCATAGCACCACTGATGGCTAGAATCTGTATTTTAGCGATAAAGGAGGAGAAACAAGTTGAACTACATTTTAAACTCCACAAGGATAGAGACTTTATCACACCACTATGTACCCAAGCCTAATCCATAATGGGCACTCAAATACT...
Task1_train_39917	This sequence change occurs on Chromosome 10. What is the medical significance of this variant — is it benign or linked to a disease?	Benign	GGAGTGTGAGTATAAAATGATGATACTGATTATATGTGTGGGTTATGAAGGCAACTTCATTTCTTTATAGTGATATTCCATTTATACATCCTATCACAGCCTATTGAGTTAACATTTTGACACTATTTAATTTTCATAGGCTGATATCTGTTTTTATAACTTCTCAGGTACTAAACAAGTTTCTTTTTTTATAAACTGAAGATTAAATTTTGTTTTAACTCAAAGATAAAACAAAGTAAAATGTAAAGAAAATGAATTTGAGAGTTATTCCAGGTTCTCAAGTGGATATGTAATGTAATTAGCTGTTCAATAATTATAGG...	GGAGTGTGAGTATAAAATGATGATACTGATTATATGTGTGGGTTATGAAGGCAACTTCATTTCTTTATAGTGATATTCCATTTATACATCCTATCACAGCCTATTGAGTTAACATTTTGACACTATTTAATTTTCATAGGCTGATATCTGTTTTTATAACTTCTCAGGTACTAAACAAGTTTCTTTTTTTATAAACTGAAGATTAAATTTTGTTTTAACTCAAAGATAAAACAAAGTAAAATGTAAAGAAAATGAATTTGAGAGTTATTCCAGGTTCTCAAGTGGATATGTAATGTAATTAGCTGTTCAATAATTATAGG...
Task1_train_39918	This variant is present on Chromosome 10. Is the change likely to result in a pathogenic outcome?	Benign	AACAAGTTTCTTTTTTTATAAACTGAAGATTAAATTTTGTTTTAACTCAAAGATAAAACAAAGTAAAATGTAAAGAAAATGAATTTGAGAGTTATTCCAGGTTCTCAAGTGGATATGTAATGTAATTAGCTGTTCAATAATTATAGGCCTTTGAGATCTAAGTTTAAAACCATCAATTTTTGAACCTCAAATTGATATCATTTCTGCATTTCTGATCTCTTGCTGCTATGAAAATATACAGCTATACATTAATAATTTTTACATGTATGATATTCATTATGGGAAAAGTATGTAGCAGCATACAAAGTTTTCTTATTGTT...	AACAAGTTTCTTTTTTTATAAACTGAAGATTAAATTTTGTTTTAACTCAAAGATAAAACAAAGTAAAATGTAAAGAAAATGAATTTGAGAGTTATTCCAGGTTCTCAAGTGGATATGTAATGTAATTAGCTGTTCAATAATTATAGGCCTTTGAGATCTAAGTTTAAAACCATCAATTTTTGAACCTCAAATTGATATCATTTCTGCATTTCTGATCTCTTGCTGCTATGAAAATATACAGCTATACATTAATAATTTTTACATGTATGATATTCATTATGGGAAAAGTATGTAGCAGCATACAAAGTTTTCTTATTGTT...
Task1_train_39919	A mutation located on Chromosome 10 is being studied. Determine whether it’s pathogenic or benign, and specify the linked disease.	Benign	TGTGTGTGTGTGCATGTGTGCGCGTGTCTGCCTGTGTGTCTGTGTGTGTGTGCATGCCTGTGTGTCTGTGTGTGTGCGTGCATGTGTGCATGTGTGTGTGTGTGTGTGCATGGGTGTGTGCATGCGTGTCTGTGCACATGTGTGTATGATTCTGATAGACACCGAGGAGTGCAGAGCAGCAGATTTAAGGATTCATTTAAAGATTCATGAGTTTGGCCAGGCACGGTGGCTCACACCTGCAATCCTAGCACTTTGGGAGGCTGAGCCGGGCGGATCAGTTGAGGTCAGGAGTTCAAGACCTGCCTGGCCAACATGGTGAA...	TGTGTGTGTGTGCATGTGTGCGCGTGTCTGCCTGTGTGTCTGTGTGTGTGTGCATGCCTGTGTGTCTGTGTGTGTGCGTGCATGTGTGCATGTGTGTGTGTGTGTGTGCATGGGTGTGTGCATGCGTGTCTGTGCACATGTGTGTATGATTCTGATAGACACCGAGGAGTGCAGAGCAGCAGATTTAAGGATTCATTTAAAGATTCATGAGTTTGGCCAGGCACGGTGGCTCACACCTGCAATCCTAGCACTTTGGGAGGCTGAGCCGGGCGGATCAGTTGAGGTCAGGAGTTCAAGACCTGCCTGGCCAACATGGTGAA...
Task1_train_39920	A variant affecting Chromosome 10 has been observed. Determine if it's benign or associated with disease.	Benign	ATTTTATTTCTAACTTGTATTATTTACTGTTATTATCTTTAATTTTTGAGCAGTATATAATTTTGCTTTACCGAAGATTTCTAAACTTTACTTGATAAATCTTTTTTTTGAGACAGAGTCTCACTCTGTCACCCAGGCTGGAGTGCAGTGGCAGGATCTCAGCTCACTGCAACCTCAGCCTCCCAGATTCAAGCGATTCTCCTGCCTCAGCCTCCCGAGTAGCTGGGACTGCAGATGCATGCCACCCTGCCCAGCTAATTTTTGTATTTTTAGTAGAGACGGGGTTTCACCATATTGGCCAGGATGGTCTCGATCTCTTG...	ATTTTATTTCTAACTTGTATTATTTACTGTTATTATCTTTAATTTTTGAGCAGTATATAATTTTGCTTTACCGAAGATTTCTAAACTTTACTTGATAAATCTTTTTTTTGAGACAGAGTCTCACTCTGTCACCCAGGCTGGAGTGCAGTGGCAGGATCTCAGCTCACTGCAACCTCAGCCTCCCAGATTCAAGCGATTCTCCTGCCTCAGCCTCCCGAGTAGCTGGGACTGCAGATGCATGCCACCCTGCCCAGCTAATTTTTGTATTTTTAGTAGAGACGGGGTTTCACCATATTGGCCAGGATGGTCTCGATCTCTTG...
Task1_train_39921	This sequence change occurs on Chromosome 10. What is the medical significance of this variant — is it benign or linked to a disease?	Benign	AGAAAGCAAATATGGTTTTGAAATTAGATATTTCATAGAAAGTATAAAAAACTTATAAGTTGTTTGTAATATTATTACCTCACATTCTTCTCCCTGTAGAAGAGGCATTTTCAGGATTCAAAATGATATTTTTATCATTGGGTTAAAATGCTCTTACAATTAGGTTAAATTCCCTATAATTTTATTATTACATTAAAATGCCCTTATAATTTTAAATTTTGTAATCTCATTTAGTGATTTAGTTTACACTTTTTTCCCTAAACTCATTGTTTACTTCCTAATTTATTTTACAAGGGTGTGTCTATGCGTTTTATTGCTAT...	AGAAAGCAAATATGGTTTTGAAATTAGATATTTCATAGAAAGTATAAAAAACTTATAAGTTGTTTGTAATATTATTACCTCACATTCTTCTCCCTGTAGAAGAGGCATTTTCAGGATTCAAAATGATATTTTTATCATTGGGTTAAAATGCTCTTACAATTAGGTTAAATTCCCTATAATTTTATTATTACATTAAAATGCCCTTATAATTTTAAATTTTGTAATCTCATTTAGTGATTTAGTTTACACTTTTTTCCCTAAACTCATTGTTTACTTCCTAATTTATTTTACAAGGGTGTGTCTATGCGTTTTATTGCTAT...
Task1_train_39922	With a mutation on Chromosome 10, classify this variant as benign or pathogenic. Include the disease if it's pathogenic.	Benign	TGAGCAATTGCATATGTAGCAGTTACTGAGTGCTACATACTATTTATGAATTTTTAAAATATTTACTCATTTTGCTTTCACAATAACCTTATGAATTACATAGTATTATTATCTCCATATTATAAATTAGAATACAGAAATACCCAGATGTTAGGTCTTTTGTTCTAGTTATGTAACTACAAATGGCAGAGGCTGACTGTAGACAAGGTCAGGCCTTCCACCAGTCCACAGTGCAACTGCCATGCTACATTGTCTACCAAATTTTAGAAAATAATTAACCCTGACTATATTCTGTCTGAAGAAAGATACATTGTAGTTTC...	TGAGCAATTGCATATGTAGCAGTTACTGAGTGCTACATACTATTTATGAATTTTTAAAATATTTACTCATTTTGCTTTCACAATAACCTTATGAATTACATAGTATTATTATCTCCATATTATAAATTAGAATACAGAAATACCCAGATGTTAGGTCTTTTGTTCTAGTTATGTAACTACAAATGGCAGAGGCTGACTGTAGACAAGGTCAGGCCTTCCACCAGTCCACAGTGCAACTGCCATGCTACATTGTCTACCAAATTTTAGAAAATAATTAACCCTGACTATATTCTGTCTGAAGAAAGATACATTGTAGTTTC...
Task1_train_39923	This variant is present on Chromosome 10. Is the change likely to result in a pathogenic outcome?	Benign	CCCAAATGACATAGAAACGATGGTAAAACTCGTATGTTTTCTTTTTTAATTTTTAAAATTTAATTTAATTATTTGTAGAGACAAAGTCTCACTTTGTTGGCCAGGATGGTCTTGAACTCCTAGCATCATGTGATCCTCCCACCTTAGCCTCCTAAAATGTTGTGATTACAGGGGTGAAGCACTCCACCCAGCCTCATATGCTTTCATATTCTCCACCTTATAAACTACAAAGAGTAATTGGTTTATTTTGCACCTTGAGATAATTTTATCTGACTTGGGATAACTATAAGAATGTATCTATACAGAAACAAACAAACAAA...	CCCAAATGACATAGAAACGATGGTAAAACTCGTATGTTTTCTTTTTTAATTTTTAAAATTTAATTTAATTATTTGTAGAGACAAAGTCTCACTTTGTTGGCCAGGATGGTCTTGAACTCCTAGCATCATGTGATCCTCCCACCTTAGCCTCCTAAAATGTTGTGATTACAGGGGTGAAGCACTCCACCCAGCCTCATATGCTTTCATATTCTCCACCTTATAAACTACAAAGAGTAATTGGTTTATTTTGCACCTTGAGATAATTTTATCTGACTTGGGATAACTATAAGAATGTATCTATACAGAAACAAACAAACAAA...
Task1_train_39924	A genetic alteration is present on Chromosome 10. Is this variant benign or disease-causing, and if the latter, which condition is involved?	Benign	AGTTGTATTAACTCCTCCTTTAATTTCTAAGTTTATTTATCTGAGTCTTCTTTATTCTTTGTTCATCTAGCTAAGTGTCTGTCAGTTTTATCTTTTCAAAAAATGAACCATGTATTTTATTGACATTCTCTATGGTTTATTCTCTATATTATTTATTTATGTTCTAATCTTTATAATTATTTTTGTTCTGCTAACTTCGGCCTTAGTTCTTTTTCTTCTAGTTTTCTGTCAAATAAAGTTAGGATGTTTATTTAAGATCTTTCTTTTTTAACGTAGGTATTTATCACTATACACTTCCCTGTTAGTACTGCTTTTGCTGC...	AGTTGTATTAACTCCTCCTTTAATTTCTAAGTTTATTTATCTGAGTCTTCTTTATTCTTTGTTCATCTAGCTAAGTGTCTGTCAGTTTTATCTTTTCAAAAAATGAACCATGTATTTTATTGACATTCTCTATGGTTTATTCTCTATATTATTTATTTATGTTCTAATCTTTATAATTATTTTTGTTCTGCTAACTTCGGCCTTAGTTCTTTTTCTTCTAGTTTTCTGTCAAATAAAGTTAGGATGTTTATTTAAGATCTTTCTTTTTTAACGTAGGTATTTATCACTATACACTTCCCTGTTAGTACTGCTTTTGCTGC...
Task1_train_39925	This alteration on Chromosome 10 may affect genome function. Does it lead to a disease or is it benign?	Benign	TAACTCCTCCTTTAATTTCTAAGTTTATTTATCTGAGTCTTCTTTATTCTTTGTTCATCTAGCTAAGTGTCTGTCAGTTTTATCTTTTCAAAAAATGAACCATGTATTTTATTGACATTCTCTATGGTTTATTCTCTATATTATTTATTTATGTTCTAATCTTTATAATTATTTTTGTTCTGCTAACTTCGGCCTTAGTTCTTTTTCTTCTAGTTTTCTGTCAAATAAAGTTAGGATGTTTATTTAAGATCTTTCTTTTTTAACGTAGGTATTTATCACTATACACTTCCCTGTTAGTACTGCTTTTGCTGCATCTCACA...	TAACTCCTCCTTTAATTTCTAAGTTTATTTATCTGAGTCTTCTTTATTCTTTGTTCATCTAGCTAAGTGTCTGTCAGTTTTATCTTTTCAAAAAATGAACCATGTATTTTATTGACATTCTCTATGGTTTATTCTCTATATTATTTATTTATGTTCTAATCTTTATAATTATTTTTGTTCTGCTAACTTCGGCCTTAGTTCTTTTTCTTCTAGTTTTCTGTCAAATAAAGTTAGGATGTTTATTTAAGATCTTTCTTTTTTAACGTAGGTATTTATCACTATACACTTCCCTGTTAGTACTGCTTTTGCTGCATCTCACA...
Task1_train_39926	A mutation on Chromosome 10 is under examination. Does this mutation cause a disorder, or is it a benign change?	Benign	TCACTGAATGTGTTAGGAGTGTTCGCTCATTCTTGTTTTCTTTTGTTTTGTTTTAGGTTTCTGCCCACTTGGCTATAGGGAATGTCATAATGGAAAATGCTATAGGCTGGAACAAAGCTGTAACTTCGTAGATAACTGTGGAGATAATACTGATGAAAATGAGTGTGGTAGCTCCTGTACTTTTGAAAAAGGCTGGTGTGGCTGGCAAAACTCCCAGGCTGACAACTTTGATTGGGTTTTAGGGGTTGGCTCTCATCAAAGCTTAAGACCTCCCAAAGACCACACACTTGGAAATGAAAATGGTAGGTTATTAGATTGTT...	TCACTGAATGTGTTAGGAGTGTTCGCTCATTCTTGTTTTCTTTTGTTTTGTTTTAGGTTTCTGCCCACTTGGCTATAGGGAATGTCATAATGGAAAATGCTATAGGCTGGAACAAAGCTGTAACTTCGTAGATAACTGTGGAGATAATACTGATGAAAATGAGTGTGGTAGCTCCTGTACTTTTGAAAAAGGCTGGTGTGGCTGGCAAAACTCCCAGGCTGACAACTTTGATTGGGTTTTAGGGGTTGGCTCTCATCAAAGCTTAAGACCTCCCAAAGACCACACACTTGGAAATGAAAATGGTAGGTTATTAGATTGTT...
Task1_train_39927	A variant on Chromosome 10 is under investigation. Evaluate whether it is clinically benign or pathogenic and name the disorder if relevant.	Benign	TGTTTTAGGTTTCTGCCCACTTGGCTATAGGGAATGTCATAATGGAAAATGCTATAGGCTGGAACAAAGCTGTAACTTCGTAGATAACTGTGGAGATAATACTGATGAAAATGAGTGTGGTAGCTCCTGTACTTTTGAAAAAGGCTGGTGTGGCTGGCAAAACTCCCAGGCTGACAACTTTGATTGGGTTTTAGGGGTTGGCTCTCATCAAAGCTTAAGACCTCCCAAAGACCACACACTTGGAAATGAAAATGGTAGGTTATTAGATTGTTGTAATTGCTTTCACATGATTTTCACAATGTACATCAAAATGTCTTTTC...	TGTTTTAGGTTTCTGCCCACTTGGCTATAGGGAATGTCATAATGGAAAATGCTATAGGCTGGAACAAAGCTGTAACTTCGTAGATAACTGTGGAGATAATACTGATGAAAATGAGTGTGGTAGCTCCTGTACTTTTGAAAAAGGCTGGTGTGGCTGGCAAAACTCCCAGGCTGACAACTTTGATTGGGTTTTAGGGGTTGGCTCTCATCAAAGCTTAAGACCTCCCAAAGACCACACACTTGGAAATGAAAATGGTAGGTTATTAGATTGTTGTAATTGCTTTCACATGATTTTCACAATGTACATCAAAATGTCTTTTC...
Task1_train_39928	Chromosome 10 is altered by this variant. Does this mutation result in a disease or is it benign?	Benign	ATAAACCTTATGTTCTTACTGGATTAAATTTTCTTTTCTTATGGCTGCATTATTTTCCACGGCCTTCATAGGATCTTTCAGTTTCTCATGCTTTAGTTAGGTCTTTACATCTCTGTTTGTCAGTCTTTTACTAGCAAAATAAATATTCTAGTTTTTTCATATGCCATAATCTGCTGGCCAGGTTATTTTCAACTTTTATTGTGAGCACCAATGTTCCATCCATTCTTTTATCATCAAATATAGAATATGTGAGATATCTTTCATTTCATGTATTTGACAACCAGGTGAATAGTTTTTGCCTTTATCATTACCATTTTGGC...	ATAAACCTTATGTTCTTACTGGATTAAATTTTCTTTTCTTATGGCTGCATTATTTTCCACGGCCTTCATAGGATCTTTCAGTTTCTCATGCTTTAGTTAGGTCTTTACATCTCTGTTTGTCAGTCTTTTACTAGCAAAATAAATATTCTAGTTTTTTCATATGCCATAATCTGCTGGCCAGGTTATTTTCAACTTTTATTGTGAGCACCAATGTTCCATCCATTCTTTTATCATCAAATATAGAATATGTGAGATATCTTTCATTTCATGTATTTGACAACCAGGTGAATAGTTTTTGCCTTTATCATTACCATTTTGGC...
Task1_train_39929	A variant found on Chromosome 10 is being studied. Please analyze its biological impact: is it benign or pathogenic, and what condition might it cause?	Benign	TTTCAGTTTCTCATGCTTTAGTTAGGTCTTTACATCTCTGTTTGTCAGTCTTTTACTAGCAAAATAAATATTCTAGTTTTTTCATATGCCATAATCTGCTGGCCAGGTTATTTTCAACTTTTATTGTGAGCACCAATGTTCCATCCATTCTTTTATCATCAAATATAGAATATGTGAGATATCTTTCATTTCATGTATTTGACAACCAGGTGAATAGTTTTTGCCTTTATCATTACCATTTTGGCTGAATAAAAAATATAAAATGGCTAAACACATGCAAAACAGTCTTTCATTAAAAAAATCTATCTTTTCAATTTGCT...	TTTCAGTTTCTCATGCTTTAGTTAGGTCTTTACATCTCTGTTTGTCAGTCTTTTACTAGCAAAATAAATATTCTAGTTTTTTCATATGCCATAATCTGCTGGCCAGGTTATTTTCAACTTTTATTGTGAGCACCAATGTTCCATCCATTCTTTTATCATCAAATATAGAATATGTGAGATATCTTTCATTTCATGTATTTGACAACCAGGTGAATAGTTTTTGCCTTTATCATTACCATTTTGGCTGAATAAAAAATATAAAATGGCTAAACACATGCAAAACAGTCTTTCATTAAAAAAATCTATCTTTTCAATTTGCT...
Task1_train_39930	Here’s a variant located on Chromosome 10. What is the predicted biological effect — harmless or disease-causing?	Benign	ATAATCTGCTGGCCAGGTTATTTTCAACTTTTATTGTGAGCACCAATGTTCCATCCATTCTTTTATCATCAAATATAGAATATGTGAGATATCTTTCATTTCATGTATTTGACAACCAGGTGAATAGTTTTTGCCTTTATCATTACCATTTTGGCTGAATAAAAAATATAAAATGGCTAAACACATGCAAAACAGTCTTTCATTAAAAAAATCTATCTTTTCAATTTGCTGTATTCTTAAAAAATATACGTGAGGCTGTTTTTTATTTGTTTATTTTTCTTTGGACACCTAATATTTCATAGATATTCTAGTCATTGTTC...	ATAATCTGCTGGCCAGGTTATTTTCAACTTTTATTGTGAGCACCAATGTTCCATCCATTCTTTTATCATCAAATATAGAATATGTGAGATATCTTTCATTTCATGTATTTGACAACCAGGTGAATAGTTTTTGCCTTTATCATTACCATTTTGGCTGAATAAAAAATATAAAATGGCTAAACACATGCAAAACAGTCTTTCATTAAAAAAATCTATCTTTTCAATTTGCTGTATTCTTAAAAAATATACGTGAGGCTGTTTTTTATTTGTTTATTTTTCTTTGGACACCTAATATTTCATAGATATTCTAGTCATTGTTC...
Task1_train_39931	A change on Chromosome 10 is being evaluated. Identify whether the variant is neutral or disease-linked. Mention the disease if applicable.	Benign	CTGCTTCTGAATGACTTTTGGGTAAATAATGACACTAAAGTAGAAATCAAGACATTTTTTGAAACTAATGAGAACAGGCATACAACATATCAGAATCTCTGGGACACAGCTAAGACACTGTTAAGAGGGAAATTTATAGCACCAAATGCCCACATCAAAAAGTTGGAAAGATCTCAAGTTAACAACCTCAAATAATCTCAAATTAACCATTGCAGTTATTGATTGGTGGGACATCTGCATAAAAGTGTGAAAGGCCATGGAAAGGGATGACTAAGGCCAATACAGAGTGAGAAATATAAGCAAGCAAATATATGTGAATA...	CTGCTTCTGAATGACTTTTGGGTAAATAATGACACTAAAGTAGAAATCAAGACATTTTTTGAAACTAATGAGAACAGGCATACAACATATCAGAATCTCTGGGACACAGCTAAGACACTGTTAAGAGGGAAATTTATAGCACCAAATGCCCACATCAAAAAGTTGGAAAGATCTCAAGTTAACAACCTCAAATAATCTCAAATTAACCATTGCAGTTATTGATTGGTGGGACATCTGCATAAAAGTGTGAAAGGCCATGGAAAGGGATGACTAAGGCCAATACAGAGTGAGAAATATAAGCAAGCAAATATATGTGAATA...
Task1_train_39932	Consider a variant on Chromosome 10. Determine its clinical classification and disease relevance.	Benign	AGAAATGCCCAATTATATTATAAGAAGTGGGAGGGAATAATTGAAAATACTCTGTTTTACAGTACTTGTACTACCCATGAAATGGGTTAGTTATGTTGTTACATAAGTTGCTTATAAAATGGTATGATGATATTTGACAGAGGATTTGGCTTGGTAGTTATAATGTATATTGCAAATTCAAAGTCAGTCCCTAGAAAAAGAATGTAAAAACAGAAGATATAAAATTGATATGTTAAGAGAGGATAAAAACAGAATCGTGAAAAGTTCAATTAAAAAACCAGAGAAGACAGAAAAAAACAGGAGGGGGGGGGAGAAAACAA...	AGAAATGCCCAATTATATTATAAGAAGTGGGAGGGAATAATTGAAAATACTCTGTTTTACAGTACTTGTACTACCCATGAAATGGGTTAGTTATGTTGTTACATAAGTTGCTTATAAAATGGTATGATGATATTTGACAGAGGATTTGGCTTGGTAGTTATAATGTATATTGCAAATTCAAAGTCAGTCCCTAGAAAAAGAATGTAAAAACAGAAGATATAAAATTGATATGTTAAGAGAGGATAAAAACAGAATCGTGAAAAGTTCAATTAAAAAACCAGAGAAGACAGAAAAAAACAGGAGGGGGGGGGAGAAAACAA...
Task1_train_39933	A mutation on Chromosome 10 is under examination. Does this mutation cause a disorder, or is it a benign change?	Benign	CTACAAACATAGGCTCCCTAAGCACAGCCACATATATCTCAGATACATGGCTTTGGTCATAGGGTCAGAGTCTAAATACCTTCTAGATACATCTTCACTATTGGTTTAGTGAGGAGGGAGAGGGACTTTCACATCTCATTTTTTAAATGAATTTGCTATATCATCTTTACATATAACACAAATTATTCTCATACAACCCATAAATAAAAGTAGTTTAAAATGTCAAGAAAACAAACCATTCCTGTACTGGCCTCCATTGCTACTTGGCTCTATATTTTCCCTTAATATATTGATGAGTCCCTCGTTAACTAGCACAGAGA...	CTACAAACATAGGCTCCCTAAGCACAGCCACATATATCTCAGATACATGGCTTTGGTCATAGGGTCAGAGTCTAAATACCTTCTAGATACATCTTCACTATTGGTTTAGTGAGGAGGGAGAGGGACTTTCACATCTCATTTTTTAAATGAATTTGCTATATCATCTTTACATATAACACAAATTATTCTCATACAACCCATAAATAAAAGTAGTTTAAAATGTCAAGAAAACAAACCATTCCTGTACTGGCCTCCATTGCTACTTGGCTCTATATTTTCCCTTAATATATTGATGAGTCCCTCGTTAACTAGCACAGAGA...
Task1_train_39934	A mutation on Chromosome 10 is under examination. Does this mutation cause a disorder, or is it a benign change?	Benign	TGTCAGGATGCATTGGGGAGAAGAGGGAGGCAGTCCCTCTTCTGGGACTGCCTCCCTTTGCAAACTGGAATTTGGGTTTGCAAAATAAGATTAGGCATGCTTGTGTACCTTTAAGTGTTGTTGATAAGAAGCCAGCAGAGAATTAGGGGTGGCAAATATTGTAGAGAAAGGACTATGATCACCTAAGCAAATTCACAATACCTGTGAAGGTGGGCTGAGTTGAGCTAGGACATAGGTAGAAATAGGTTGAAAGGATGGCTATAAGGAAAGGTCCCCATCCATTATCACAGAAGGAAAGAATAGGTCAGCCCAGAGTCAAG...	TGTCAGGATGCATTGGGGAGAAGAGGGAGGCAGTCCCTCTTCTGGGACTGCCTCCCTTTGCAAACTGGAATTTGGGTTTGCAAAATAAGATTAGGCATGCTTGTGTACCTTTAAGTGTTGTTGATAAGAAGCCAGCAGAGAATTAGGGGTGGCAAATATTGTAGAGAAAGGACTATGATCACCTAAGCAAATTCACAATACCTGTGAAGGTGGGCTGAGTTGAGCTAGGACATAGGTAGAAATAGGTTGAAAGGATGGCTATAAGGAAAGGTCCCCATCCATTATCACAGAAGGAAAGAATAGGTCAGCCCAGAGTCAAG...
Task1_train_39935	Located on Chromosome 10, this mutation has been observed. What is its biological consequence — is it benign or pathogenic, and which disease is associated if any?	Benign	CCAGGAAATCAAAGCTGCAGGGAACAGTGACTGTGCCACTGCATTCTAGCCTGGGTAATAGAGTGAGGCCTGGTCTAGGAAAAAAAAAAATTTCCTCCCTTCCCATATTAGTTCTTGAATTTAGGAGCCAAAAGGCCTTTGATACTGTGTACCCCATAAGCTTCTCTAGACCATCTTCCTGCCTCGGCAGCTGGGTATAATCTCTTTCTCTTCTGAAACTCTATCTGCAGGGATACACCCCTACCTTTCTCTGGCATTCATCTTTCTGTTTTGCATTAGAGTCCAGTATGCGCATGATTTATTCTGCCCTGCAAGACTTG...	CCAGGAAATCAAAGCTGCAGGGAACAGTGACTGTGCCACTGCATTCTAGCCTGGGTAATAGAGTGAGGCCTGGTCTAGGAAAAAAAAAAATTTCCTCCCTTCCCATATTAGTTCTTGAATTTAGGAGCCAAAAGGCCTTTGATACTGTGTACCCCATAAGCTTCTCTAGACCATCTTCCTGCCTCGGCAGCTGGGTATAATCTCTTTCTCTTCTGAAACTCTATCTGCAGGGATACACCCCTACCTTTCTCTGGCATTCATCTTTCTGTTTTGCATTAGAGTCCAGTATGCGCATGATTTATTCTGCCCTGCAAGACTTG...
Task1_train_39936	Assess the clinical impact of this variant found on Chromosome 10. State whether it’s pathogenic or benign, and the disease if applicable.	Benign	CTTTATCAGATTCCTCTTCATTGGCTTAAGAAGATACAAGACAGGAGTCTCCAATCCTTAGACCATGGACCAATATCAACCATGGCCAGTTAGCAACCCGGTAACAAAGCAGGAGGTGAGCAAGGGTGAGGGAGCATTCCTGCCTGAGCTCTGCCTCCTGTCAGATCAGCGGTGGCATTAGATTCTCATAGAAGCACAAACCCTATTATGAACTGTGCATGCAAGGGATCTAGGCTGTGCACTCCTTATGAGAATCTAACTAAAGCCTGATGATCTGAGATGGAAGAGTTTCATCCTAAAACCATCCCCTCCAACACCAC...	CTTTATCAGATTCCTCTTCATTGGCTTAAGAAGATACAAGACAGGAGTCTCCAATCCTTAGACCATGGACCAATATCAACCATGGCCAGTTAGCAACCCGGTAACAAAGCAGGAGGTGAGCAAGGGTGAGGGAGCATTCCTGCCTGAGCTCTGCCTCCTGTCAGATCAGCGGTGGCATTAGATTCTCATAGAAGCACAAACCCTATTATGAACTGTGCATGCAAGGGATCTAGGCTGTGCACTCCTTATGAGAATCTAACTAAAGCCTGATGATCTGAGATGGAAGAGTTTCATCCTAAAACCATCCCCTCCAACACCAC...
Task1_train_39937	A variant was discovered on Chromosome 10. What is its functional impact — neutral or pathogenic? State the disease if pathogenic.	Benign	CTTTTTAAATCTGGGAATTGACTAGTTTTTAATCTGAGTGATCTATTGTTAGAAGAAAAAAAAAATCTTTGCAAGTTGTTGAATCTTTTAAAAGTCCTAAGGGGAACGTGTTTACTGTCTGTGACAGTGGTTCTTAACAATGTCAGATTTAACAACTTTTTTATAATGAATATGCTGTAATGACTCCCTTTGATAGCCTATTTTATCTACCGAGTGAAATAAACCATCCTAAACAGCATGTATGGCTTCTCATGATTCTGTGGGTTGACTAGGCAGTTCTGCTTGACAAAGTAGAGGCAGTTGGGGCTCTGGGGCCCCTA...	CTTTTTAAATCTGGGAATTGACTAGTTTTTAATCTGAGTGATCTATTGTTAGAAGAAAAAAAAAATCTTTGCAAGTTGTTGAATCTTTTAAAAGTCCTAAGGGGAACGTGTTTACTGTCTGTGACAGTGGTTCTTAACAATGTCAGATTTAACAACTTTTTTATAATGAATATGCTGTAATGACTCCCTTTGATAGCCTATTTTATCTACCGAGTGAAATAAACCATCCTAAACAGCATGTATGGCTTCTCATGATTCTGTGGGTTGACTAGGCAGTTCTGCTTGACAAAGTAGAGGCAGTTGGGGCTCTGGGGCCCCTA...
Task1_train_39938	Assess the clinical impact of this variant found on Chromosome 10. State whether it’s pathogenic or benign, and the disease if applicable.	Benign	ATGGCTTCTCATGATTCTGTGGGTTGACTAGGCAGTTCTGCTTGACAAAGTAGAGGCAGTTGGGGCTCTGGGGCCCCTAAGAAGTCAAACTGGCCTCACTCACATAACTCAGCTGGCACTGGCTGCTGGCCTGGAGCTCAGCTGGGGATGCTGGCCTAGGACGACCCTTCTCTTACAGGTTAAACTCTCATGTGGCTTCTCGGGCTTCCTGGTAGCATGGCAGCAAGGTTCAAAGAAAGAGCATTCCTGGAAGCGAAGGTGGAAGCTGCAAGCCTCTTAAGGCCAAGCCCCAAACTTACACACCATTATTTCGCTGCATT...	ATGGCTTCTCATGATTCTGTGGGTTGACTAGGCAGTTCTGCTTGACAAAGTAGAGGCAGTTGGGGCTCTGGGGCCCCTAAGAAGTCAAACTGGCCTCACTCACATAACTCAGCTGGCACTGGCTGCTGGCCTGGAGCTCAGCTGGGGATGCTGGCCTAGGACGACCCTTCTCTTACAGGTTAAACTCTCATGTGGCTTCTCGGGCTTCCTGGTAGCATGGCAGCAAGGTTCAAAGAAAGAGCATTCCTGGAAGCGAAGGTGGAAGCTGCAAGCCTCTTAAGGCCAAGCCCCAAACTTACACACCATTATTTCGCTGCATT...
Task1_train_39939	A mutation on Chromosome 10 has been found. Is it harmful or harmless? What disease, if any, does it cause?	Benign	GTGGGTTGACTAGGCAGTTCTGCTTGACAAAGTAGAGGCAGTTGGGGCTCTGGGGCCCCTAAGAAGTCAAACTGGCCTCACTCACATAACTCAGCTGGCACTGGCTGCTGGCCTGGAGCTCAGCTGGGGATGCTGGCCTAGGACGACCCTTCTCTTACAGGTTAAACTCTCATGTGGCTTCTCGGGCTTCCTGGTAGCATGGCAGCAAGGTTCAAAGAAAGAGCATTCCTGGAAGCGAAGGTGGAAGCTGCAAGCCTCTTAAGGCCAAGCCCCAAACTTACACACCATTATTTCGCTGCATTCTATTGGCCAAAACAGGT...	GTGGGTTGACTAGGCAGTTCTGCTTGACAAAGTAGAGGCAGTTGGGGCTCTGGGGCCCCTAAGAAGTCAAACTGGCCTCACTCACATAACTCAGCTGGCACTGGCTGCTGGCCTGGAGCTCAGCTGGGGATGCTGGCCTAGGACGACCCTTCTCTTACAGGTTAAACTCTCATGTGGCTTCTCGGGCTTCCTGGTAGCATGGCAGCAAGGTTCAAAGAAAGAGCATTCCTGGAAGCGAAGGTGGAAGCTGCAAGCCTCTTAAGGCCAAGCCCCAAACTTACACACCATTATTTCGCTGCATTCTATTGGCCAAAACAGGT...