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train · 48.9k rows

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ID stringlengths 13 17	question stringlengths 88 1.13k	answer stringlengths 6 156	reference_sequence stringlengths 4.1k 4.1k	variant_sequence stringlengths 4.1k 4.1k
Task1_train_40400	Given this variant on Chromosome 10, classify it as benign or pathogenic. Include the disorder it may cause if applicable.	Benign	TGGAAATAAGGAAGATGGGCAGCTGTGATGGGGAGGGCTTGCTGACGTCCCCAGATCAACCCCGCGGGCCGGCGTGTGATGCGTCGAGACAGGAATTTCATGCTGGGGTGCCACATCCCCCCCAGGGGGAGAACTTGGCAGCAGACCTGGGGCTCACGGCACTCATCCTGGACCAAGATCAGCAGGGAATCCCATCCTGCCCAGGGGAAGGCTGGATAAGAGGAGCTGCATCCGAGTGGCCCCTACTATCTTCTGAGAAGCATCTCCAGCCATCCCAGGCACAACCAGAGACATCCATCTTTGACGTGCTCAAGGAGCAG...	TGGAAATAAGGAAGATGGGCAGCTGTGATGGGGAGGGCTTGCTGACGTCCCCAGATCAACCCCGCGGGCCGGCGTGTGATGCGTCGAGACAGGAATTTCATGCTGGGGTGCCACATCCCCCCCAGGGGGAGAACTTGGCAGCAGACCTGGGGCTCACGGCACTCATCCTGGACCAAGATCAGCAGGGAATCCCATCCTGCCCAGGGGAAGGCTGGATAAGAGGAGCTGCATCCGAGTGGCCCCTACTATCTTCTGAGAAGCATCTCCAGCCATCCCAGGCACAACCAGAGACATCCATCTTTGACGTGCTCAAGGAGCAG...
Task1_train_40401	Located on Chromosome 10, this mutation has been observed. What is its biological consequence — is it benign or pathogenic, and which disease is associated if any?	Benign	AGGGGAAGGCTGGATAAGAGGAGCTGCATCCGAGTGGCCCCTACTATCTTCTGAGAAGCATCTCCAGCCATCCCAGGCACAACCAGAGACATCCATCTTTGACGTGCTCAAGGAGCAGGCCCAGCCACCTGAAAATGGGAAAGAGACTTCTCCAAGCCATCCAGGTTTTAAGGACCAGGGAGCAGATTCTTCCCAAATCCATGTACCTGTGGAACCTCAGGAAGATAACAACTTGCCCACTCATGGAGGACAGGAGCAGGCTTTGGGATCAGAACTTCAAAGTCAGCTCCCCAAAGGCACCCTGTCTGATACTCCAACTT...	AGGGGAAGGCTGGATAAGAGGAGCTGCATCCGAGTGGCCCCTACTATCTTCTGAGAAGCATCTCCAGCCATCCCAGGCACAACCAGAGACATCCATCTTTGACGTGCTCAAGGAGCAGGCCCAGCCACCTGAAAATGGGAAAGAGACTTCTCCAAGCCATCCAGGTTTTAAGGACCAGGGAGCAGATTCTTCCCAAATCCATGTACCTGTGGAACCTCAGGAAGATAACAACTTGCCCACTCATGGAGGACAGGAGCAGGCTTTGGGATCAGAACTTCAAAGTCAGCTCCCCAAAGGCACCCTGTCTGATACTCCAACTT...
Task1_train_40402	This alteration occurs on Chromosome 10. Is it associated with a disease or is it a benign variant?	Benign	GAGATGGGGCAGGTGTAGCCTTGGGCATCTGCATCAGATCCCAGGGCTGTCAGCTGTCACAGAGCTGGCTTTGTTGTGATTAGCAGCGGGCCACAGATCTAAGGTAGCATCTCCCCCCCACCCGCCACTGTTTTCTAAGACAGAGATCCTTCCTTGCAGTTTGATAAACAGTACCCTTAAATCACAGAACCACAAACAATACCACCTTTCCACAATTTGCATTAAACTAAGTAAAATCTTGGTGGGATGTGTGTGGTGGAGGGGGGAGCACAGCAGTGTAATTTCTTGAGAAAGCGAAGTTAGACTAGTAGTTTGCGTTT...	GAGATGGGGCAGGTGTAGCCTTGGGCATCTGCATCAGATCCCAGGGCTGTCAGCTGTCACAGAGCTGGCTTTGTTGTGATTAGCAGCGGGCCACAGATCTAAGGTAGCATCTCCCCCCCACCCGCCACTGTTTTCTAAGACAGAGATCCTTCCTTGCAGTTTGATAAACAGTACCCTTAAATCACAGAACCACAAACAATACCACCTTTCCACAATTTGCATTAAACTAAGTAAAATCTTGGTGGGATGTGTGTGGTGGAGGGGGGAGCACAGCAGTGTAATTTCTTGAGAAAGCGAAGTTAGACTAGTAGTTTGCGTTT...
Task1_train_40403	Chromosome 10 carries this variant. Does this mutation lead to a specific disease, or is it non-pathogenic?	Benign	CTTAGATAAACAAAGAATCATCGAGACATGGGACATACTTATATTAAAAAACATGTTCATTTATCTGAAATTCAAATCAGCTGAACATCCTGTCCTTTGTCTGGCAACCATGCCGGTGGCAGAAGGGGACTGGGGGTACATAACACCTGTCACGAGGCACACATTGGAAACGCTGTCCCAGGTCTTACCTGTGCCAGCTCCGTTTACTCCTCATTCTGCATCTCCCAGTACTTAGGCCTGCAGACCGCTTTATCGTGTTTGCCCTCTTGTCCAATGACACACTTTTAGTTTTCTGGCATCCTTGACTGCCTGGAGCAGCT...	CTTAGATAAACAAAGAATCATCGAGACATGGGACATACTTATATTAAAAAACATGTTCATTTATCTGAAATTCAAATCAGCTGAACATCCTGTCCTTTGTCTGGCAACCATGCCGGTGGCAGAAGGGGACTGGGGGTACATAACACCTGTCACGAGGCACACATTGGAAACGCTGTCCCAGGTCTTACCTGTGCCAGCTCCGTTTACTCCTCATTCTGCATCTCCCAGTACTTAGGCCTGCAGACCGCTTTATCGTGTTTGCCCTCTTGTCCAATGACACACTTTTAGTTTTCTGGCATCCTTGACTGCCTGGAGCAGCT...
Task1_train_40404	This variant is found on Chromosome 10. What is the clinical effect of this variant — benign or pathogenic? State the disease if applicable.	Benign	GTCAGGATTCCACCTAGAAGCCTTCAGAGCATGGGAATCCATTGAGCTCAAAGATCCTGTGATAGGGAGGATTCAGGAGGTTCTCCTTGAGGACCCCGAACTTTCTATTTCTGCGTGGCCCCCTTCAGTTGTTCATTAAGTGAGGTGTCGCCTTGCCCGTCTGTAAATTGGTGTCCTGAGCCTAGAGCCCCTCCCCTAGCCTTAGTTGGGTTCAGATACCCCTGGAAGAATCCAGATAAATTAATCTGCTCACCAGAAATTTGCTTTATAAAATACGAACATTTAGTTAAATTTAGCTTCATTTTCTGGGTCATTCTCCA...	GTCAGGATTCCACCTAGAAGCCTTCAGAGCATGGGAATCCATTGAGCTCAAAGATCCTGTGATAGGGAGGATTCAGGAGGTTCTCCTTGAGGACCCCGAACTTTCTATTTCTGCGTGGCCCCCTTCAGTTGTTCATTAAGTGAGGTGTCGCCTTGCCCGTCTGTAAATTGGTGTCCTGAGCCTAGAGCCCCTCCCCTAGCCTTAGTTGGGTTCAGATACCCCTGGAAGAATCCAGATAAATTAATCTGCTCACCAGAAATTTGCTTTATAAAATACGAACATTTAGTTAAATTTAGCTTCATTTTCTGGGTCATTCTCCA...
Task1_train_40405	A mutation has occurred on Chromosome 10. What is the medical relevance of this mutation?	Benign	TTCTAGAGATGAGATCTCACAATGTTACCCAGGCTGTTCTCAAGCTCCTGGCCTCAAGGGATCCTCCCACCTCAGCCTCCCAAAGTGTTGGGATTACAGGTGTGAGTGAGCCACCGCACACGGCCCAGAATTTTTTTCAGAATTGTGTGTTTATGAACTTTCTCCATAAGGACAAATATTGAGTCTTGATCTCTGTGTCATTTTTCAGCTACTTCCTGAGAAGTTCCCCCATGACAAGCAGAACTGTGAAACCCATTTTCCAATAGCAGAGATGAACCCCTGCATGTGAGGCTCCGGCCCTGCGGCTTGGTGGTGCCCTT...	TTCTAGAGATGAGATCTCACAATGTTACCCAGGCTGTTCTCAAGCTCCTGGCCTCAAGGGATCCTCCCACCTCAGCCTCCCAAAGTGTTGGGATTACAGGTGTGAGTGAGCCACCGCACACGGCCCAGAATTTTTTTCAGAATTGTGTGTTTATGAACTTTCTCCATAAGGACAAATATTGAGTCTTGATCTCTGTGTCATTTTTCAGCTACTTCCTGAGAAGTTCCCCCATGACAAGCAGAACTGTGAAACCCATTTTCCAATAGCAGAGATGAACCCCTGCATGTGAGGCTCCGGCCCTGCGGCTTGGTGGTGCCCTT...
Task1_train_40406	Located on Chromosome 10, this mutation has been observed. What is its biological consequence — is it benign or pathogenic, and which disease is associated if any?	Benign	CTACTGCTCCCACTTGACAGAGGAGAGTGAAGCTCTGAGAGGCCCGGTCACAGGACTGTGGCTGGCTGGGCTGGGACGGGACCCTGGTCTGCCTGCCTCGGGGGTCCCAGCTTGGTTGGATGATGAGATGACTCATGGCCTCTCCATGTCATCCACAAAAGTGGGCATCATTGCCACTTCCCAGAGGCCCCAAGGGGTCATAAAGTCCAACAAGCTGTCTCAACAAAGCTGTTTCCAAATCCTCTGGGACAGGATGGCTGTCCAGAGAGGCCCTGGCTGAATGGCCTTCGAGTCTGAGTGCCTCTCAAAGGGAGGATCAG...	CTACTGCTCCCACTTGACAGAGGAGAGTGAAGCTCTGAGAGGCCCGGTCACAGGACTGTGGCTGGCTGGGCTGGGACGGGACCCTGGTCTGCCTGCCTCGGGGGTCCCAGCTTGGTTGGATGATGAGATGACTCATGGCCTCTCCATGTCATCCACAAAAGTGGGCATCATTGCCACTTCCCAGAGGCCCCAAGGGGTCATAAAGTCCAACAAGCTGTCTCAACAAAGCTGTTTCCAAATCCTCTGGGACAGGATGGCTGTCCAGAGAGGCCCTGGCTGAATGGCCTTCGAGTCTGAGTGCCTCTCAAAGGGAGGATCAG...
Task1_train_40407	Here’s a variant located on Chromosome 10. What is the predicted biological effect — harmless or disease-causing?	Benign	AGGCCCGGTCACAGGACTGTGGCTGGCTGGGCTGGGACGGGACCCTGGTCTGCCTGCCTCGGGGGTCCCAGCTTGGTTGGATGATGAGATGACTCATGGCCTCTCCATGTCATCCACAAAAGTGGGCATCATTGCCACTTCCCAGAGGCCCCAAGGGGTCATAAAGTCCAACAAGCTGTCTCAACAAAGCTGTTTCCAAATCCTCTGGGACAGGATGGCTGTCCAGAGAGGCCCTGGCTGAATGGCCTTCGAGTCTGAGTGCCTCTCAAAGGGAGGATCAGGGTCTCGGTTCCTCTTGCCCCTGCCAGCAGCCTTGCCAT...	AGGCCCGGTCACAGGACTGTGGCTGGCTGGGCTGGGACGGGACCCTGGTCTGCCTGCCTCGGGGGTCCCAGCTTGGTTGGATGATGAGATGACTCATGGCCTCTCCATGTCATCCACAAAAGTGGGCATCATTGCCACTTCCCAGAGGCCCCAAGGGGTCATAAAGTCCAACAAGCTGTCTCAACAAAGCTGTTTCCAAATCCTCTGGGACAGGATGGCTGTCCAGAGAGGCCCTGGCTGAATGGCCTTCGAGTCTGAGTGCCTCTCAAAGGGAGGATCAGGGTCTCGGTTCCTCTTGCCCCTGCCAGCAGCCTTGCCAT...
Task1_train_40408	A variant on Chromosome 10 has been observed. Is this a neutral mutation, or does it result in a disease? If so, which one?	Benign	TTTTTTTTTTTTTTTTTTTTTTTTTTTGAGATAGAGTCTTACTCTGTCACCCAGGCTGGAGTGCAGTAACACAATCTCAGCTCACTGCAACATCTGCCTCCCCGATTCAAGTGATTCTCCTACCTCAGCCTCCTGAGTAGCTGGGACTACAGGCACGCACCACCACGCCTGGCTAATTTTTTTTTTTTTTTTTTTGGTATTTTTGGTAGAGATGGGGTTTTGCCACATTGGCCAGGCTGGTCTTGAACTCCTGACCTCAGATGATCTGCCCGCCTCAGCCTCCCAAAGTGCTGGGATTACAGGTGTGAACCACCACGCCC...	TTTTTTTTTTTTTTTTTTTTTTTTTTTGAGATAGAGTCTTACTCTGTCACCCAGGCTGGAGTGCAGTAACACAATCTCAGCTCACTGCAACATCTGCCTCCCCGATTCAAGTGATTCTCCTACCTCAGCCTCCTGAGTAGCTGGGACTACAGGCACGCACCACCACGCCTGGCTAATTTTTTTTTTTTTTTTTTTGGTATTTTTGGTAGAGATGGGGTTTTGCCACATTGGCCAGGCTGGTCTTGAACTCCTGACCTCAGATGATCTGCCCGCCTCAGCCTCCCAAAGTGCTGGGATTACAGGTGTGAACCACCACGCCC...
Task1_train_40409	A variant found on Chromosome 10 is being studied. Please analyze its biological impact: is it benign or pathogenic, and what condition might it cause?	Benign	GATAATAAAATTGAAATACAACTAAACATTCTGCTCAGAAATATTTTTTTAAAAGATTTTTCTTGTGTTCAAGTACATAAGAATTAGATTTGCATTTGGAATACTTTGGCCACTGATCTCAGGTCTGAAAATTTAAAGTATCTTAAAATGTAACACTGCCATCTGCGGAAAGTAGTCTCATATGTAGCATGATAGCCTTTATTATCTAGATTTACTATGACATATATGCTAGTTACTTACACTTTTAATATTTTTTTCTGATAGTATTATAATACCGCCTTTTATTAGTTTTCTGGTAGTGATAACTACAGATAAATAAA...	GATAATAAAATTGAAATACAACTAAACATTCTGCTCAGAAATATTTTTTTAAAAGATTTTTCTTGTGTTCAAGTACATAAGAATTAGATTTGCATTTGGAATACTTTGGCCACTGATCTCAGGTCTGAAAATTTAAAGTATCTTAAAATGTAACACTGCCATCTGCGGAAAGTAGTCTCATATGTAGCATGATAGCCTTTATTATCTAGATTTACTATGACATATATGCTAGTTACTTACACTTTTAATATTTTTTTCTGATAGTATTATAATACCGCCTTTTATTAGTTTTCTGGTAGTGATAACTACAGATAAATAAA...
Task1_train_40410	Here is a genetic alteration on Chromosome 10. Based on the data, is it a benign variant or a cause of disease?	Benign	TAGTGGGTATTTTATTCTTTTTTATGGCTGAATAGTATTTCATTTTATGGATATGCCATAATTTATCTGTTATCAGTTGATGGACATTTGGGTTGTTTCTACCTTTGGGCTGTTATGAATAGTGCTGCTATGAACATGTGTGTTCCAGTTTCTGTATGGACACATGTTTTCCTTTCTCTTGGGTAGCTACCTAGGAATGGAAATGCTGGATCATATATTCACTCTGTTTGAAGAACTGCCAGACTGTTTTCCAAAGCAGCTATACCATTTTACAATCCCACTAGCAGTGCATGAGGATTCTGATTTCTCCACATCCTTGC...	TAGTGGGTATTTTATTCTTTTTTATGGCTGAATAGTATTTCATTTTATGGATATGCCATAATTTATCTGTTATCAGTTGATGGACATTTGGGTTGTTTCTACCTTTGGGCTGTTATGAATAGTGCTGCTATGAACATGTGTGTTCCAGTTTCTGTATGGACACATGTTTTCCTTTCTCTTGGGTAGCTACCTAGGAATGGAAATGCTGGATCATATATTCACTCTGTTTGAAGAACTGCCAGACTGTTTTCCAAAGCAGCTATACCATTTTACAATCCCACTAGCAGTGCATGAGGATTCTGATTTCTCCACATCCTTGC...
Task1_train_40411	Assess the clinical impact of this variant found on Chromosome 10. State whether it’s pathogenic or benign, and the disease if applicable.	Benign	GTAGGATGTGAGGAGAAGGAGGAGTCGAATATGATGCCCTTATTCCCAGCATGGTTAATATGGAGCATGATGACATCCTTAATTCAAACGGAGGGAAGAGGCTGTGTTGAGTTTGGGATGATGTGGGGGGTAGGATGGCCAGGAGGCCACTGAAAATGCTGGTCTAGAGCTCAGGGCTGGGCTGTCAGGGCTGAGTCAGAACCAGAGAGGTGGATTTGGGGGTCTTCTGGAAAGTTCTCAGAGTACATGAGGTTCTCCAGGGGGAAAATACAGAATGAGAAGAGGGCAAAGAGAGAACATGGAAGAACAAGGATACTTAA...	GTAGGATGTGAGGAGAAGGAGGAGTCGAATATGATGCCCTTATTCCCAGCATGGTTAATATGGAGCATGATGACATCCTTAATTCAAACGGAGGGAAGAGGCTGTGTTGAGTTTGGGATGATGTGGGGGGTAGGATGGCCAGGAGGCCACTGAAAATGCTGGTCTAGAGCTCAGGGCTGGGCTGTCAGGGCTGAGTCAGAACCAGAGAGGTGGATTTGGGGGTCTTCTGGAAAGTTCTCAGAGTACATGAGGTTCTCCAGGGGGAAAATACAGAATGAGAAGAGGGCAAAGAGAGAACATGGAAGAACAAGGATACTTAA...
Task1_train_40412	The following genetic variant occurs on Chromosome 10. Classify its clinical effect — pathogenic or benign — and list any associated condition.	Benign	CCACGAATGTGGCCACAGGGAAGATGCTGGTGTCATGTGCTCAGGTAGTGTGGATATCACCTTGCTCTGTGTATCTGCAACTCTGAGTCAATATTACCACACATAAGTATGTGTGCGTACATATGTGTGTGCTCTACAGCTTACCTGCTTTGCAGTAAGTCATGTCTTAATTGATATTGGAGGGCAGGTGGTACTGGCCCTTTTCATAGACAATGAAGGTCAAGGGATCATCGGCCAGTCCTTCTAAAGCTGGATATAGTGGAGGCAGGCTTCAGTCTCACCCCCCAGAGCCTGCTGATGCAATCACCTCATGGAGTGGT...	CCACGAATGTGGCCACAGGGAAGATGCTGGTGTCATGTGCTCAGGTAGTGTGGATATCACCTTGCTCTGTGTATCTGCAACTCTGAGTCAATATTACCACACATAAGTATGTGTGCGTACATATGTGTGTGCTCTACAGCTTACCTGCTTTGCAGTAAGTCATGTCTTAATTGATATTGGAGGGCAGGTGGTACTGGCCCTTTTCATAGACAATGAAGGTCAAGGGATCATCGGCCAGTCCTTCTAAAGCTGGATATAGTGGAGGCAGGCTTCAGTCTCACCCCCCAGAGCCTGCTGATGCAATCACCTCATGGAGTGGT...
Task1_train_40413	Given a variant located on Chromosome 10, assess whether it is benign or pathogenic. Indicate the associated disease if pathogenic.	Benign	CATAAAGAGAGGTGGGGAAGTGGGCTAAGCGTGGGAGGGTGGCAGCAGGTGATAAACAGTTGGCTCAAGAGTCAGCTCGGCACTGGGAACAAGAGCAGGACCTCCCAGAAGATCATTAGGAATCATTAGGCTCATGATAGGATGAGGCTCAAGGTGGGCCCCTTGCTTTTTCATGTTTCTGTGGGTTGGGTAGGGAGGAAGCTGGAGTCTCTGAAAACCCAGAATTAGATGTGATATTGGAGGGTGGAGGGTGCTGGTGACCTGTCTCCTGTGGGATCCTGTTCCAAGTGGTCAGAAAAGATCCTTATCTATGGGCTCAG...	CATAAAGAGAGGTGGGGAAGTGGGCTAAGCGTGGGAGGGTGGCAGCAGGTGATAAACAGTTGGCTCAAGAGTCAGCTCGGCACTGGGAACAAGAGCAGGACCTCCCAGAAGATCATTAGGAATCATTAGGCTCATGATAGGATGAGGCTCAAGGTGGGCCCCTTGCTTTTTCATGTTTCTGTGGGTTGGGTAGGGAGGAAGCTGGAGTCTCTGAAAACCCAGAATTAGATGTGATATTGGAGGGTGGAGGGTGCTGGTGACCTGTCTCCTGTGGGATCCTGTTCCAAGTGGTCAGAAAAGATCCTTATCTATGGGCTCAG...
Task1_train_40414	A mutation is present on Chromosome 10. Based on this information, is the variant pathogenic or benign? Provide the disease if relevant.	Benign	AGCTGCTCAGTCCCAGTCAACGCCCAGGCCAGGTGAGTCCCCAGCATCCTTCATCGGGATGTCCCTTCTCTTTCTGCCCAGTTACCTCTTCCCCACTCCACAGAGCTCTCCTGCTTTTCTGTGCGGATACTGTGGGGCATATTATTTTTCCTCCCACCACTCTGTAACTGAGACCCCAGCATAGTGCTTCAACAGACATAGGGTTCAGGAGGCTTCTGTCTTCTGTTCAATTTATTTCAGGTTTCATGAAGCAGTTTCATACTGTACAATGGACAAGCCTTACAGGTTCAGGAAGTGGCCTCATGTTTAATGAGCTTTAG...	AGCTGCTCAGTCCCAGTCAACGCCCAGGCCAGGTGAGTCCCCAGCATCCTTCATCGGGATGTCCCTTCTCTTTCTGCCCAGTTACCTCTTCCCCACTCCACAGAGCTCTCCTGCTTTTCTGTGCGGATACTGTGGGGCATATTATTTTTCCTCCCACCACTCTGTAACTGAGACCCCAGCATAGTGCTTCAACAGACATAGGGTTCAGGAGGCTTCTGTCTTCTGTTCAATTTATTTCAGGTTTCATGAAGCAGTTTCATACTGTACAATGGACAAGCCTTACAGGTTCAGGAAGTGGCCTCATGTTTAATGAGCTTTAG...
Task1_train_40415	This mutation on Chromosome 10 may be significant. Is it associated with any clinical condition, or is it benign?	Benign	GAATAATAAGGACTAGTACACCTGGTTACCCTGGGCAACAAATAAAACTTTAATAATGATAAGGAGTTGCTTTACGCATGCGCTCTTTCCAGATACTCTCTTCTTCCAGGCTGTAGGTCTTGACCAGATCACTGAAGTGGTCTCTCCGTGATATAAAATCCTGATTCATTAGCATTAAGTCACCAGGGAATTCTGATATGCAGAAAAGATTTCGGTTTGTTAGGCCTGCGATGGACCGTTCCGGTTTCTTTGCGGGGAGGAATGATTTGCGATCATTTCCATGGTATGTTAAACATTTTTTTGGTTCTTTTGACTTGAAA...	GAATAATAAGGACTAGTACACCTGGTTACCCTGGGCAACAAATAAAACTTTAATAATGATAAGGAGTTGCTTTACGCATGCGCTCTTTCCAGATACTCTCTTCTTCCAGGCTGTAGGTCTTGACCAGATCACTGAAGTGGTCTCTCCGTGATATAAAATCCTGATTCATTAGCATTAAGTCACCAGGGAATTCTGATATGCAGAAAAGATTTCGGTTTGTTAGGCCTGCGATGGACCGTTCCGGTTTCTTTGCGGGGAGGAATGATTTGCGATCATTTCCATGGTATGTTAAACATTTTTTTGGTTCTTTTGACTTGAAA...
Task1_train_40416	This genomic variant is located on Chromosome 10. Can you determine its pathogenicity and name any linked disease?	Benign	ACAGAAGGCAGCTGGGAGTAAAGTGGGGAGGAGTGCTTCCTGCCACCTGCTGTTGTGGTCAGGGAGTCTGGGCTTTGGCCTTTGGCTGGTGGTTCGTGTTACAGTTGAAGATGTTGATGGCTGGATCAACACACATCACTGTTACCGTAATCCACGCAGGAGCCACATGCTCTGGAGATTTGGGGATTGCAGTAGGAAGAAACTGGTTTTCAAAAGGTCCTTTTGAGGTCACTGAGCTCAGGCCTATCTTACACAGGTCAGACAACTTTAACACAGGGAGGTCCTGCCTGGCTCCTCTCACTGTCTTGGATAAATGGACA...	ACAGAAGGCAGCTGGGAGTAAAGTGGGGAGGAGTGCTTCCTGCCACCTGCTGTTGTGGTCAGGGAGTCTGGGCTTTGGCCTTTGGCTGGTGGTTCGTGTTACAGTTGAAGATGTTGATGGCTGGATCAACACACATCACTGTTACCGTAATCCACGCAGGAGCCACATGCTCTGGAGATTTGGGGATTGCAGTAGGAAGAAACTGGTTTTCAAAAGGTCCTTTTGAGGTCACTGAGCTCAGGCCTATCTTACACAGGTCAGACAACTTTAACACAGGGAGGTCCTGCCTGGCTCCTCTCACTGTCTTGGATAAATGGACA...
Task1_train_40417	The following genetic variant occurs on Chromosome 10. Classify its clinical effect — pathogenic or benign — and list any associated condition.	Benign	AATAAGTTTGAGAAACAGAGGACCGGAACAGAAATGGCATCATAAATAAAATAAGACAAAAAATAGTTCCAGGAGTTCTCACTCAACCATTTGCCTTTCTTCTTTTCTGTCTATAAAATGAAGCAAGGTCCTGGGGGATTGTGGGGGGTAGGGTTATGCCCAAATCACTCTTATATCCCACCTATTTAAAAACATACAGATAGAGAGAGAGCCATATATATATACATATATTATATATATTTTTTGGGGTCAGGGGAGGTAGTAGTAGTTTTTAATTTGTGCTTAATTAAAAATTCAGTTCCTCTACCATCAGGAAAGTG...	AATAAGTTTGAGAAACAGAGGACCGGAACAGAAATGGCATCATAAATAAAATAAGACAAAAAATAGTTCCAGGAGTTCTCACTCAACCATTTGCCTTTCTTCTTTTCTGTCTATAAAATGAAGCAAGGTCCTGGGGGATTGTGGGGGGTAGGGTTATGCCCAAATCACTCTTATATCCCACCTATTTAAAAACATACAGATAGAGAGAGAGCCATATATATATACATATATTATATATATTTTTTGGGGTCAGGGGAGGTAGTAGTAGTTTTTAATTTGTGCTTAATTAAAAATTCAGTTCCTCTACCATCAGGAAAGTG...
Task1_train_40418	Consider this mutation on Chromosome 10. Is this a benign change or a disease-causing variant?	Benign	ATCTAACCTTTTCACCCCAAATCTGTTCCTCCTTTTTCTTGCCACTCCAACATTGATGAAATGTAGAGTAATTGAAATTTACTTCGGAGATACAGCAAGGGACTCCAAAAGGCCATGGAGAGAGAATTTCAACTAAAATTGAAAAGCCATACAGAGGTCTGCATAAAAAACAAACAGCACACCACAAATCAAAACCTTTAAGATAAAAACTTAATTAGCATCTACAGGTTGAATGAGCTAGTAACTTATGCCAATCTTATCATTACATTAGCTGAAAAGAAAACGAACTGACAGATTAATCAAAGAACAAAGCAGTAGCT...	ATCTAACCTTTTCACCCCAAATCTGTTCCTCCTTTTTCTTGCCACTCCAACATTGATGAAATGTAGAGTAATTGAAATTTACTTCGGAGATACAGCAAGGGACTCCAAAAGGCCATGGAGAGAGAATTTCAACTAAAATTGAAAAGCCATACAGAGGTCTGCATAAAAAACAAACAGCACACCACAAATCAAAACCTTTAAGATAAAAACTTAATTAGCATCTACAGGTTGAATGAGCTAGTAACTTATGCCAATCTTATCATTACATTAGCTGAAAAGAAAACGAACTGACAGATTAATCAAAGAACAAAGCAGTAGCT...
Task1_train_40419	An alteration has been detected on Chromosome 10. Is it pathogenic, and if so, what disease is involved?	Benign	TCTTGCTCTGTTGCCCAGGCCGGAGTGCAGTGGTGCGATCTCGGCTCACTGCAAGCTCCGCCTCCTGGGTTCATGCCATTCTCCTGCCTCAGCCTCCCGAGTAGCTGGGACTACAGGCGCCCGCCACCACGCCCAGCCAATTTTTTTTGTATTTTTAGTAGAGATGAGGTTTCACCATGTTAGCCAGGATGGTCTCAATCTCCTGACCTCGTGATCCACCCGCCTCGGCCTCCCAAAGTGCTGGGATTACAGGCGTGAGCCACCGCGCCCGGCGTTTGTAGAGTATATTTTTAATCAGTGATTATACAAAACTCAAGAAC...	TCTTGCTCTGTTGCCCAGGCCGGAGTGCAGTGGTGCGATCTCGGCTCACTGCAAGCTCCGCCTCCTGGGTTCATGCCATTCTCCTGCCTCAGCCTCCCGAGTAGCTGGGACTACAGGCGCCCGCCACCACGCCCAGCCAATTTTTTTTGTATTTTTAGTAGAGATGAGGTTTCACCATGTTAGCCAGGATGGTCTCAATCTCCTGACCTCGTGATCCACCCGCCTCGGCCTCCCAAAGTGCTGGGATTACAGGCGTGAGCCACCGCGCCCGGCGTTTGTAGAGTATATTTTTAATCAGTGATTATACAAAACTCAAGAAC...
Task1_train_40420	Chromosome 10 is altered by this variant. Does this mutation result in a disease or is it benign?	Benign	GAGTGTTTACCGAAGTGTAAGGTGAATATTATCTAGTAGAGTAACTGCATTTTTAATCTCATCTGGCACCAACTGTCTTTTAGAAAGTTACAATGTGTTGTTTGGGGGACATTCTTCTTTAGAAGGAAAAGAGTCTAATTAGTGGATATTAAGTAATTAAATAATACATACTATCAAATATTATGAGAGTCACATGAACCATGAAGTCTTCACTTAATTTAGGAGAAATGGGGAATATTTTCTATCATTCCTGATAACAGAACTAGATATTTCAAGATCATAGTCATGGAATGTAATCCATAATACCAAACAGGGTGCTT...	GAGTGTTTACCGAAGTGTAAGGTGAATATTATCTAGTAGAGTAACTGCATTTTTAATCTCATCTGGCACCAACTGTCTTTTAGAAAGTTACAATGTGTTGTTTGGGGGACATTCTTCTTTAGAAGGAAAAGAGTCTAATTAGTGGATATTAAGTAATTAAATAATACATACTATCAAATATTATGAGAGTCACATGAACCATGAAGTCTTCACTTAATTTAGGAGAAATGGGGAATATTTTCTATCATTCCTGATAACAGAACTAGATATTTCAAGATCATAGTCATGGAATGTAATCCATAATACCAAACAGGGTGCTT...
Task1_train_40421	A mutation located on Chromosome 10 is being studied. Determine whether it’s pathogenic or benign, and specify the linked disease.	Benign	AATGGGGAATATTTTCTATCATTCCTGATAACAGAACTAGATATTTCAAGATCATAGTCATGGAATGTAATCCATAATACCAAACAGGGTGCTTTACTTTGAAGCCATTGACCATTAAATTTGATTGTTAGTAGCACAGGCTACCAAAAAATAGCAAGGAATATGGTATCCACACAGATCTCGGCTGGCCTCAAGTAATCAAAAGTGAGAATGAAACATACATGACACAACTGGGGACCTCTGGGTTTCTGAGACGTGGGCTACAAGATTATATTAGGTAGAAAACTAAAGGAAATGTATTCCAAGCAAAAGTGGCAAGG...	AATGGGGAATATTTTCTATCATTCCTGATAACAGAACTAGATATTTCAAGATCATAGTCATGGAATGTAATCCATAATACCAAACAGGGTGCTTTACTTTGAAGCCATTGACCATTAAATTTGATTGTTAGTAGCACAGGCTACCAAAAAATAGCAAGGAATATGGTATCCACACAGATCTCGGCTGGCCTCAAGTAATCAAAAGTGAGAATGAAACATACATGACACAACTGGGGACCTCTGGGTTTCTGAGACGTGGGCTACAAGATTATATTAGGTAGAAAACTAAAGGAAATGTATTCCAAGCAAAAGTGGCAAGG...
Task1_train_40422	A variant has been detected on Chromosome 10. What is its effect — pathogenic or benign? If pathogenic, name the disease.	Benign	ATCCCTCCCCAGGGGAAGGCCTTCCTTGGGGCTGCCCCTCCTCCACTCTGGCAGCATTGGGACTTGAATCTTGTGGCCCCGTCACAACTGTACTCAGCTACTCCAGCTCCTTGTGTGACCTCTCAGCCCCCAGGCTCTGAGCTACCTGAGGTGAGGTGGGGCCACACTGGTCCCCACCTCGGTGCAGCACACACAGCCCCATCCTGGGAGTGCCACCCAGGTTTCCTCTAACTGTGCTTTCCAAGGGCTGGAAGGACCTCTTCCTCTATGCCAGGTGTGCTAGAGTGGCCCCAGCCGAGAACCTGACTGGGACCAAGCCC...	ATCCCTCCCCAGGGGAAGGCCTTCCTTGGGGCTGCCCCTCCTCCACTCTGGCAGCATTGGGACTTGAATCTTGTGGCCCCGTCACAACTGTACTCAGCTACTCCAGCTCCTTGTGTGACCTCTCAGCCCCCAGGCTCTGAGCTACCTGAGGTGAGGTGGGGCCACACTGGTCCCCACCTCGGTGCAGCACACACAGCCCCATCCTGGGAGTGCCACCCAGGTTTCCTCTAACTGTGCTTTCCAAGGGCTGGAAGGACCTCTTCCTCTATGCCAGGTGTGCTAGAGTGGCCCCAGCCGAGAACCTGACTGGGACCAAGCCC...
Task1_train_40423	This sequence change occurs on Chromosome 10. What is the medical significance of this variant — is it benign or linked to a disease?	Benign	TGCAGACTTCCCTGGCACTGGCTCGCTGCCACGCAAATTAAGTAAAAATCAATATCCTCCGGTCTGTAAAACATCGTGTTAGCAATCACACTGCAAACAACTTATATAATACCCCTCACTCCATACCCAAATAATGGCGAATGTTTTTGTTAAAAGGCAAGTCTAAAATAAACAGGAAAAAGAAAAGAAAAGAAAAGGCAATCTTACAGGTTCCTCCTTCGGCAAAACCTTTCCACGACTTGGGTGAGGAGATAATCTTTCTGTGATTATGACCAAACCCTCCTGTCACTTAGCAACACATAATTAAGGAATATGTTTTC...	TGCAGACTTCCCTGGCACTGGCTCGCTGCCACGCAAATTAAGTAAAAATCAATATCCTCCGGTCTGTAAAACATCGTGTTAGCAATCACACTGCAAACAACTTATATAATACCCCTCACTCCATACCCAAATAATGGCGAATGTTTTTGTTAAAAGGCAAGTCTAAAATAAACAGGAAAAAGAAAAGAAAAGAAAAGGCAATCTTACAGGTTCCTCCTTCGGCAAAACCTTTCCACGACTTGGGTGAGGAGATAATCTTTCTGTGATTATGACCAAACCCTCCTGTCACTTAGCAACACATAATTAAGGAATATGTTTTC...
Task1_train_40424	A variant was discovered on Chromosome 10. Please indicate if this mutation results in a known disease or if it's non-harmful.	Benign	AAAGAAAAGGCAATCTTACAGGTTCCTCCTTCGGCAAAACCTTTCCACGACTTGGGTGAGGAGATAATCTTTCTGTGATTATGACCAAACCCTCCTGTCACTTAGCAACACATAATTAAGGAATATGTTTTCAGATCCGCTTTGCAAGCCCGGCCATTATCAGATGAAATTACTGGAGCAACAAATGTCATCGCCATGCAAATCAGTTGGTTGCAAAGAAAGAATGTTTGACTGAGAGAGCAGGCACAGGCCCTCGGAAAAATTATCTGACGTCCCTCCTGCCGCACATGTATTTGAGAAAGTCAAATAATGATGTGATC...	AAAGAAAAGGCAATCTTACAGGTTCCTCCTTCGGCAAAACCTTTCCACGACTTGGGTGAGGAGATAATCTTTCTGTGATTATGACCAAACCCTCCTGTCACTTAGCAACACATAATTAAGGAATATGTTTTCAGATCCGCTTTGCAAGCCCGGCCATTATCAGATGAAATTACTGGAGCAACAAATGTCATCGCCATGCAAATCAGTTGGTTGCAAAGAAAGAATGTTTGACTGAGAGAGCAGGCACAGGCCCTCGGAAAAATTATCTGACGTCCCTCCTGCCGCACATGTATTTGAGAAAGTCAAATAATGATGTGATC...
Task1_train_40425	A mutation on Chromosome 10 is under review. Please evaluate whether this mutation is benign or pathogenic and specify the disease if necessary.	Benign	CGCACATGTATTTGAGAAAGTCAAATAATGATGTGATCAGACTTCAAAAAAATCCATGAGACAAAATCAGAATCTATACGACAAAGCAGAAAATCAGGCCAGTTGCTCAGTCTCCACTTGGAAACAAAATGCAAAATGCCTGGAGGTCATCTCTAGGAGGTAATATTAATAGCACACACGGGCCACACAGCGATGGCAGAGAAACTTAAGGTGGTCTCTGCAGGGTTGTGAGGTCCAGCGCCTCGGTCCCCGCCTACAGCTGCTTCAGGGCTATTTTCAAAAAGGTAGATCTTATTGTTTCATCCTGATTTTCACAAGCT...	CGCACATGTATTTGAGAAAGTCAAATAATGATGTGATCAGACTTCAAAAAAATCCATGAGACAAAATCAGAATCTATACGACAAAGCAGAAAATCAGGCCAGTTGCTCAGTCTCCACTTGGAAACAAAATGCAAAATGCCTGGAGGTCATCTCTAGGAGGTAATATTAATAGCACACACGGGCCACACAGCGATGGCAGAGAAACTTAAGGTGGTCTCTGCAGGGTTGTGAGGTCCAGCGCCTCGGTCCCCGCCTACAGCTGCTTCAGGGCTATTTTCAAAAAGGTAGATCTTATTGTTTCATCCTGATTTTCACAAGCT...
Task1_train_40426	This variant lies on Chromosome 10. Based on this context, is the mutation pathogenic or benign? If pathogenic, what disease does it cause?	Benign	TGGCAGAGAAACTTAAGGTGGTCTCTGCAGGGTTGTGAGGTCCAGCGCCTCGGTCCCCGCCTACAGCTGCTTCAGGGCTATTTTCAAAAAGGTAGATCTTATTGTTTCATCCTGATTTTCACAAGCTATTCAGGAAAAAAAAAAATCATTTGAAAAGGATTCTGTTTTCTGAATGACGTAGGGGAGGCTGGCGGGGAGGAAAGAATTATGTTTGAAAGGAAGAAAACTGATTTACATTTTAAATTTGTGGTCAAGACTCTAGAGTTAAAATAAAAATTGTAAATGGTGCTCTGAGGACGCCCACCTAGGACTTCATCCAC...	TGGCAGAGAAACTTAAGGTGGTCTCTGCAGGGTTGTGAGGTCCAGCGCCTCGGTCCCCGCCTACAGCTGCTTCAGGGCTATTTTCAAAAAGGTAGATCTTATTGTTTCATCCTGATTTTCACAAGCTATTCAGGAAAAAAAAAAATCATTTGAAAAGGATTCTGTTTTCTGAATGACGTAGGGGAGGCTGGCGGGGAGGAAAGAATTATGTTTGAAAGGAAGAAAACTGATTTACATTTTAAATTTGTGGTCAAGACTCTAGAGTTAAAATAAAAATTGTAAATGGTGCTCTGAGGACGCCCACCTAGGACTTCATCCAC...
Task1_train_40427	A mutation on Chromosome 10 is under review. Please evaluate whether this mutation is benign or pathogenic and specify the disease if necessary.	Benign	CAGCTGCTTCAGGGCTATTTTCAAAAAGGTAGATCTTATTGTTTCATCCTGATTTTCACAAGCTATTCAGGAAAAAAAAAAATCATTTGAAAAGGATTCTGTTTTCTGAATGACGTAGGGGAGGCTGGCGGGGAGGAAAGAATTATGTTTGAAAGGAAGAAAACTGATTTACATTTTAAATTTGTGGTCAAGACTCTAGAGTTAAAATAAAAATTGTAAATGGTGCTCTGAGGACGCCCACCTAGGACTTCATCCACAATGTCCAAGGAAACACACGCCATAAATCACACCTGGCACATGTTGTGAAGAAAACCACCTAC...	CAGCTGCTTCAGGGCTATTTTCAAAAAGGTAGATCTTATTGTTTCATCCTGATTTTCACAAGCTATTCAGGAAAAAAAAAAATCATTTGAAAAGGATTCTGTTTTCTGAATGACGTAGGGGAGGCTGGCGGGGAGGAAAGAATTATGTTTGAAAGGAAGAAAACTGATTTACATTTTAAATTTGTGGTCAAGACTCTAGAGTTAAAATAAAAATTGTAAATGGTGCTCTGAGGACGCCCACCTAGGACTTCATCCACAATGTCCAAGGAAACACACGCCATAAATCACACCTGGCACATGTTGTGAAGAAAACCACCTAC...
Task1_train_40428	This sequence change occurs on Chromosome 10. What is the medical significance of this variant — is it benign or linked to a disease?	Benign	GGGACACAGAACAGGGAACAGCACCGTTATGACCTCTGCTTCTCTGTAGGGAGGACTTCTCCCACACGGAGAACTCGGCTCTAGAATTGGATAGGGGCGAAGGTGATGGTGGGCTGAAAGGAAGGAGCGGGGACAGGCAAGCTTCTCCCACCCTGCAGTCTCCCCTCCTCCATTTCGTTTTGTATGTAGCAGCCAGGGTTGTTCTTAAACCCAGACCTGACAATTCTCTGCTGAAAAACCTTTCATGTCACTCCACTGCTCTCACCAGAAAGACCACACTCAGGCCAAGCACTGTGGTTCCCGCCTGAAATCCCAGCGCT...	GGGACACAGAACAGGGAACAGCACCGTTATGACCTCTGCTTCTCTGTAGGGAGGACTTCTCCCACACGGAGAACTCGGCTCTAGAATTGGATAGGGGCGAAGGTGATGGTGGGCTGAAAGGAAGGAGCGGGGACAGGCAAGCTTCTCCCACCCTGCAGTCTCCCCTCCTCCATTTCGTTTTGTATGTAGCAGCCAGGGTTGTTCTTAAACCCAGACCTGACAATTCTCTGCTGAAAAACCTTTCATGTCACTCCACTGCTCTCACCAGAAAGACCACACTCAGGCCAAGCACTGTGGTTCCCGCCTGAAATCCCAGCGCT...
Task1_train_40429	Chromosome 10 is altered by this variant. Does this mutation result in a disease or is it benign?	Benign	CAGTAGCTCTTTATGTGAGGAAGGTTTGGGGAGAGTGATCTTCAGTTTTCACTTGCACCTTTGAATATTCTGCCATGTTTGAATTCCTTAGAATGATCAAGCATCTTTTTTGTTGTTGGGGTTTTGTTTTTTGTTTTGTTTTGTTTTGTTTGAGACAGAGTTTTACCCTGTCACATGGGCTGGAGTGCAGTGGCATGGTCATGGCTCACTGCAACCTTGACCATCTGGGCTCTAGTGATCCTCAGCCTCCCCGAGTAGCTGAGATCACAAGTGCTAATTTTGGAAAAATTGTTTGTAGAGACAGGGTCTCACTATGTTAT...	CAGTAGCTCTTTATGTGAGGAAGGTTTGGGGAGAGTGATCTTCAGTTTTCACTTGCACCTTTGAATATTCTGCCATGTTTGAATTCCTTAGAATGATCAAGCATCTTTTTTGTTGTTGGGGTTTTGTTTTTTGTTTTGTTTTGTTTTGTTTGAGACAGAGTTTTACCCTGTCACATGGGCTGGAGTGCAGTGGCATGGTCATGGCTCACTGCAACCTTGACCATCTGGGCTCTAGTGATCCTCAGCCTCCCCGAGTAGCTGAGATCACAAGTGCTAATTTTGGAAAAATTGTTTGTAGAGACAGGGTCTCACTATGTTAT...
Task1_train_40430	A variant found on Chromosome 10 is being studied. Please analyze its biological impact: is it benign or pathogenic, and what condition might it cause?	Benign	TGGTGGGATGCCACAGCACGGGTTGGGGGCCCGCTTGTGTTGAGAAAACCACCCCGCATTCACTGTCCTCCTGGGAAATGCATGTGGTGAGAGAGGACACAGGAGGGACTGGCTGTCGACTGGGCAAAACCACTTTTTAACTGAGAGAATGGCATCAGGGAGCTAGAGGGTGGCTACCCTTGGGTGACATGAGTTGTACAACGTTGCGCTCTTAGGCCCAGTTTCCCAGTGAGGAGTGAGCGGGGTCCTACAGTGCTCTGGAATACAGTGTCCTCCGCTAGCTCAGGGATGCCCTCCGCAGCAGTCTTACCATACAGCTT...	TGGTGGGATGCCACAGCACGGGTTGGGGGCCCGCTTGTGTTGAGAAAACCACCCCGCATTCACTGTCCTCCTGGGAAATGCATGTGGTGAGAGAGGACACAGGAGGGACTGGCTGTCGACTGGGCAAAACCACTTTTTAACTGAGAGAATGGCATCAGGGAGCTAGAGGGTGGCTACCCTTGGGTGACATGAGTTGTACAACGTTGCGCTCTTAGGCCCAGTTTCCCAGTGAGGAGTGAGCGGGGTCCTACAGTGCTCTGGAATACAGTGTCCTCCGCTAGCTCAGGGATGCCCTCCGCAGCAGTCTTACCATACAGCTT...
Task1_train_40431	This genomic variant is located on Chromosome 10. Can you determine its pathogenicity and name any linked disease?	Benign	CTCACTTAACCTTGTGTATGGCATTAAATTCCTCCAAGTCCAGTTTTTCTTGTCCCCAAAATGCAGGTAATAGGACCCACCTGATAGGGCTATTTTGAGGATTAAATGAGATGTTGAGGGGAAATGTTTAAGTCTCTTTTAATTCAGAGTGTTAAGTTTAGCCTAAAGCTGCCTCCTTACATGTTTTAAGTTCAGCCTAAAGAATTCTCCGTATACAGTGAACTGTAACCTAAATAGTTACAGCTATGGGTACAAGAGTAGGTTACAGCCTGTTTGTAGGATACAGCTTGGGCTCTGTCCTAGATGTGTAAACAGGCTGT...	CTCACTTAACCTTGTGTATGGCATTAAATTCCTCCAAGTCCAGTTTTTCTTGTCCCCAAAATGCAGGTAATAGGACCCACCTGATAGGGCTATTTTGAGGATTAAATGAGATGTTGAGGGGAAATGTTTAAGTCTCTTTTAATTCAGAGTGTTAAGTTTAGCCTAAAGCTGCCTCCTTACATGTTTTAAGTTCAGCCTAAAGAATTCTCCGTATACAGTGAACTGTAACCTAAATAGTTACAGCTATGGGTACAAGAGTAGGTTACAGCCTGTTTGTAGGATACAGCTTGGGCTCTGTCCTAGATGTGTAAACAGGCTGT...
Task1_train_40432	A genomic change on Chromosome 10 is noted. Classify this variant as benign or pathogenic, and name the disease if relevant.	Benign	CTTCCCCAGGCCAGGCGAGGGGGCCCAGCATCAACGTTCTTTCTCCATCCCTGGCACAAACTGGACGTGAGTGCACCAGCCTGGCTTTGGGGGCAGCAGCCACGTTCACAGCCTGGCTCTGCCACTGTGGCTAGTGAGCACTAGGTGTGAAGATACCCACCTCACAGGCTGCAAGGGCATTTTGCTGTACACAGGAAATTCAGCTGCTGCCATTAGTGTGGTGGTGGTGATTACGAATCTGCTTACCTACTGCTTTGCAGTGACATCTCTGTGGCATTTATAGACAAGTGCGTGGTCTTCCCAAGTCAATGGATAAGTAG...	CTTCCCCAGGCCAGGCGAGGGGGCCCAGCATCAACGTTCTTTCTCCATCCCTGGCACAAACTGGACGTGAGTGCACCAGCCTGGCTTTGGGGGCAGCAGCCACGTTCACAGCCTGGCTCTGCCACTGTGGCTAGTGAGCACTAGGTGTGAAGATACCCACCTCACAGGCTGCAAGGGCATTTTGCTGTACACAGGAAATTCAGCTGCTGCCATTAGTGTGGTGGTGGTGATTACGAATCTGCTTACCTACTGCTTTGCAGTGACATCTCTGTGGCATTTATAGACAAGTGCGTGGTCTTCCCAAGTCAATGGATAAGTAG...
Task1_train_40433	Given a variant located on Chromosome 10, assess whether it is benign or pathogenic. Indicate the associated disease if pathogenic.	Benign	GCTGGGAGTGCAGAGGCAACGTCTGCCCATTCATCTTTCTACCCTGCTGAGTCATTTGTTCCCAAAAGACGATCCAAAAGCCCTACATTCTGTATTCCAAAGAGACATGGGAGTGGAGGGCATGGAGGTGCTGAGTCACTTGCTTCTGTTGCACTTGGAAGCCCCAAGAAGCACAGACACAGATCATCCACTCAGCGTGAAAAACGTGCTCTTTCAGGAGGCACCACAACTGCGGCTGAAGGAAACAGCTCCTCCTCCTGGGTAGAAAGAGCTGGGAGGAAACCTTTGCCTATACAGAAAGTTCTGTGAGCTCCACAAAC...	GCTGGGAGTGCAGAGGCAACGTCTGCCCATTCATCTTTCTACCCTGCTGAGTCATTTGTTCCCAAAAGACGATCCAAAAGCCCTACATTCTGTATTCCAAAGAGACATGGGAGTGGAGGGCATGGAGGTGCTGAGTCACTTGCTTCTGTTGCACTTGGAAGCCCCAAGAAGCACAGACACAGATCATCCACTCAGCGTGAAAAACGTGCTCTTTCAGGAGGCACCACAACTGCGGCTGAAGGAAACAGCTCCTCCTCCTGGGTAGAAAGAGCTGGGAGGAAACCTTTGCCTATACAGAAAGTTCTGTGAGCTCCACAAAC...
Task1_train_40434	Chromosome 10 carries this variant. Does this mutation lead to a specific disease, or is it non-pathogenic?	Benign	TGGGATCTGTGCTTTTTCTGGGGGATGTTGGCCTGCAGGATGCAGAATAAATTTATACTATTTGCCTAAGATAATCCCTTAGAGGAGCAGTCATTTCACAAAATCACAATCAAAAATCTTCTCTGCACCACCAAAGCCAAAAAGTAAGTTGGGGGAAGTGTCCACACTCTTGCTGCCCTCCTCTGAGATGAGTGTATGAGTGTTTGAGATCTGGCTCTCATTATTAATGAAGAGCCTTTGGTGAAAAGTACTATAAATCCAAATTATTATTTCACACCATGACACATGGTTTAAAAATGAGGATGTGCTTTAACTGGGGT...	TGGGATCTGTGCTTTTTCTGGGGGATGTTGGCCTGCAGGATGCAGAATAAATTTATACTATTTGCCTAAGATAATCCCTTAGAGGAGCAGTCATTTCACAAAATCACAATCAAAAATCTTCTCTGCACCACCAAAGCCAAAAAGTAAGTTGGGGGAAGTGTCCACACTCTTGCTGCCCTCCTCTGAGATGAGTGTATGAGTGTTTGAGATCTGGCTCTCATTATTAATGAAGAGCCTTTGGTGAAAAGTACTATAAATCCAAATTATTATTTCACACCATGACACATGGTTTAAAAATGAGGATGTGCTTTAACTGGGGT...
Task1_train_40435	Here’s a variant located on Chromosome 10. What is the predicted biological effect — harmless or disease-causing?	Benign	GTTTCAATTCAAATAAAACCGTCATAGAAAAAAAAAACAAACATCATGAGAGCCAGCATGCTTTTATTTTGAAAGTAATTAAAAACCAGCTCAATTAACCACCCAAAGTTATTGCTGGTTCATGACTCACTTGTGTTTGCTGCCCAGCACGCCTGCCCTCTGTGCCCAGGGAGTGTGTGTGCTCACTAGTAGGTGCTAAGAGCTCTTCTCTCCTAAGATGACTGGAAGGATTGCACCCGCTGCTGTCTCCATCCGCCTGAACCACACATCCAAAACCATTCCCCACTTTCAGCCCCTTCCCAGAGACTACAACCACCATG...	GTTTCAATTCAAATAAAACCGTCATAGAAAAAAAAAACAAACATCATGAGAGCCAGCATGCTTTTATTTTGAAAGTAATTAAAAACCAGCTCAATTAACCACCCAAAGTTATTGCTGGTTCATGACTCACTTGTGTTTGCTGCCCAGCACGCCTGCCCTCTGTGCCCAGGGAGTGTGTGTGCTCACTAGTAGGTGCTAAGAGCTCTTCTCTCCTAAGATGACTGGAAGGATTGCACCCGCTGCTGTCTCCATCCGCCTGAACCACACATCCAAAACCATTCCCCACTTTCAGCCCCTTCCCAGAGACTACAACCACCATG...
Task1_train_40436	An alteration has been detected on Chromosome 10. Is it pathogenic, and if so, what disease is involved?	Benign	TTTGCTTAAGAGCATCAAGCTGTAGACAGGCCTCCTGCACCAAGCTGGAGCAGCCAGAGCCCAGGGCAGGACCTGCCCCAGCCTCTCCACTGCTGGAGCTGGGCCTTTCACCTCAGCCTCCACCTTAAGGCAGGAGGTGTTTCCTCCCCATTCTTTGCAGTCAGCAAACTGTCTAACTCAGCCACAGCAATCCTCTTAAGGAAACTTTGTGCCCAGGTGGTTTTCTGTCCTGGAAATACATTACTTGGCTTATTTCAGGCTGGCTTCTAGCTTGCTAAACCCAGGGCTCAGGGCTCGCAGAGTGAAGGGTGCACATCACA...	TTTGCTTAAGAGCATCAAGCTGTAGACAGGCCTCCTGCACCAAGCTGGAGCAGCCAGAGCCCAGGGCAGGACCTGCCCCAGCCTCTCCACTGCTGGAGCTGGGCCTTTCACCTCAGCCTCCACCTTAAGGCAGGAGGTGTTTCCTCCCCATTCTTTGCAGTCAGCAAACTGTCTAACTCAGCCACAGCAATCCTCTTAAGGAAACTTTGTGCCCAGGTGGTTTTCTGTCCTGGAAATACATTACTTGGCTTATTTCAGGCTGGCTTCTAGCTTGCTAAACCCAGGGCTCAGGGCTCGCAGAGTGAAGGGTGCACATCACA...
Task1_train_40437	A genomic variant on Chromosome 10 is under review. What is the biological outcome — benign or pathogenic?	Benign	CTCCACCTGCCTCCTCTCCTTCTCCCACCCTCAGAGCCAATCATACACAGGACCCAGTGGATAGGACTGGAGTTCCGGAAGCCAGCTCCCCAGCGCCTCCTCCGAGCTGCCATCCTTCTCTCCTGTGGCAGGGGTGTCTTCCTCTGAAATCAGTGTCCATCTCAGTCCTGGCCGCACCTCCACAGGCTCCCGATGTCTGGCAAGAAAAGCTAAGCAGGGACTTCCAAACGTGTTTGAACAAAACTCCAATGAAGAAAAACATTTCCAATCACTGCTCGATGCACTTCCCACCCCCATCAAGGTGTAACTCAGCGAGAATT...	CTCCACCTGCCTCCTCTCCTTCTCCCACCCTCAGAGCCAATCATACACAGGACCCAGTGGATAGGACTGGAGTTCCGGAAGCCAGCTCCCCAGCGCCTCCTCCGAGCTGCCATCCTTCTCTCCTGTGGCAGGGGTGTCTTCCTCTGAAATCAGTGTCCATCTCAGTCCTGGCCGCACCTCCACAGGCTCCCGATGTCTGGCAAGAAAAGCTAAGCAGGGACTTCCAAACGTGTTTGAACAAAACTCCAATGAAGAAAAACATTTCCAATCACTGCTCGATGCACTTCCCACCCCCATCAAGGTGTAACTCAGCGAGAATT...
Task1_train_40438	This alteration on Chromosome 10 may affect genome function. Does it lead to a disease or is it benign?	Benign	AGTCATGATTCTGGAGACTGTCAGTGGGTGGGGAGGCTGGCTGCAGGAGTGGATGCGTGAGTCTAATTGAGTAGGCAAAGAGCTTTCTGGGCACTGGATATGTCTTTGGAGGGTGCATCTTCACATCCTTGCACTATTACTACATGATCTTTCTAAAAATGTGTTTAAAATCTATTTTAATATTGAAAACAGACACCATCACTGCTGCTGCGGAAAACAATTTAGTGGTTCCTCCAAAGTTCAATGTAGAATAAACCTATAATATCAACTGGCAGTCCTGCTTCTAGGCCTGTACTCCAAAGAATTGAAGACAGGGACTC...	AGTCATGATTCTGGAGACTGTCAGTGGGTGGGGAGGCTGGCTGCAGGAGTGGATGCGTGAGTCTAATTGAGTAGGCAAAGAGCTTTCTGGGCACTGGATATGTCTTTGGAGGGTGCATCTTCACATCCTTGCACTATTACTACATGATCTTTCTAAAAATGTGTTTAAAATCTATTTTAATATTGAAAACAGACACCATCACTGCTGCTGCGGAAAACAATTTAGTGGTTCCTCCAAAGTTCAATGTAGAATAAACCTATAATATCAACTGGCAGTCCTGCTTCTAGGCCTGTACTCCAAAGAATTGAAGACAGGGACTC...
Task1_train_40439	This mutation occurs on Chromosome 10. Does this change lead to a known medical condition, or is it benign?	Benign	TCCTGTCTCAAAAATAAAAAATAAAAATAATAAACCTGTCATCTCCTGCCAATTCTAGAGAGTAGACAGTGTCTGGCAATGGGAAGTTGGGAGAGGATGTGCTATTGATTGAGTTGATTCTTAAACAAATTTCCACTTAACCCTCCATTTTGGTACCATCTTCACTACATGCAAAAATAACTTGAGTCTTTTGGGGGTATTTCAGTAAGCACCTTTCTCAGATCCACTTGATCAATTGTTTATCACTTAATAAAATCCTTCTGCATTCTTTTTGGGTTCCTGCGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTTTTAGCT...	TCCTGTCTCAAAAATAAAAAATAAAAATAATAAACCTGTCATCTCCTGCCAATTCTAGAGAGTAGACAGTGTCTGGCAATGGGAAGTTGGGAGAGGATGTGCTATTGATTGAGTTGATTCTTAAACAAATTTCCACTTAACCCTCCATTTTGGTACCATCTTCACTACATGCAAAAATAACTTGAGTCTTTTGGGGGTATTTCAGTAAGCACCTTTCTCAGATCCACTTGATCAATTGTTTATCACTTAATAAAATCCTTCTGCATTCTTTTTGGGTTCCTGCGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTTTTAGCT...