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5,200
Synchronization and oscillatory dynamics in heterogeneous mutually inhibited neurons
q-bio.NC
We study some mechanisms responsible for synchronous oscillations and loss of synchrony at physiologically relevant frequencies (10-200 Hz) in a network of heterogeneous inhibitory neurons. We focus on the factors that determine the level of synchrony and frequency of the network response, as well as the effects of mil...
biology
5,201
Frequency control in synchronized networks of inhibitory neurons
q-bio.NC
We analyze the control of frequency for a synchronized inhibitory neuronal network. The analysis is done for a reduced membrane model with a biophysically-based synaptic influence. We argue that such a reduced model can quantitatively capture the frequency behavior of a larger class of neuronal models. We show that in ...
biology
5,202
Coding Strategies in Monkey V1 and Inferior Temporal Cortices
q-bio.NC
We would like to know whether the statistics of neuronal responses vary across cortical areas. We examined stimulus-elicited spike count response distributions in V1 and IT cortices of awake monkeys. In both areas the distribution of spike counts for each stimulus was well-described by a Gaussian, with the log of the v...
biology
5,203
Measuring the dynamics of neural responses in primary auditory cortex
q-bio.NC
We review recent developments in the measurement of the dynamics of the response properties of auditory cortical neurons to broadband sounds, which is closely related to the perception of timbre. The emphasis is on a method that characterizes the spectro-temporal properties of single neurons to dynamic, broadband sound...
biology
5,204
Synaptic Transmission: An Information-Theoretic Perspective
q-bio.NC
Here we analyze synaptic transmission from an information-theoretic perspective. We derive closed-form expressions for the lower-bounds on the capacity of a simple model of a cortical synapse under two explicit coding paradigms. Under the ``signal estimation'' paradigm, we assume the signal to be encoded in the mean fi...
biology
5,205
Sensory Coding with Dynamically Competitive Networks
q-bio.NC
Studies of insect olfactory processing indicate that odors are represented by rich spatio-temporal patterns of neural activity. These patterns are very difficult to predict a priori, yet they are stimulus specific and reliable upon repeated stimulation with the same input. We formulate here a theoretical framework in w...
biology
5,206
Temporal structure in neuronal activity during working memory in Macaque parietal cortex
q-bio.NC
A number of cortical structures are reported to have elevated single unit firing rates sustained throughout the memory period of a working memory task. How the nervous system forms and maintains these memories is unknown but reverberating neuronal network activity is thought to be important. We studied the temporal str...
biology
5,207
Structured psychosocial stress and therapeutic failure
q-bio.NC
Generalized language-of-thought arguments appropriate to interacting cognitive modules permit exploration of how disease states interact with medical treatment. The interpenetrating feedback between treatment and response to it creates a kind of idiotypic hall-of-mirrors generating a synergistic pattern of efficacy, tr...
biology
5,208
Different ocular dominance map formation by influence of orientation columns in visual cortices
q-bio.NC
In animal experiments, the observed orientation preference (OP) and ocular dominance (OD) columns in the visual cortex of the brain show various pattern types. Here, we show that the different visual map formations in various species are due to the crossover behavior in anisotropic systems composed of orientational and...
biology
5,209
What do neural nets and quantum theory tell us about mind and reality?
q-bio.NC
This paper proposes an approach to framing and answering fundamental questions about consciousness. It argues that many of the more theoretical debates about consciousness, such as debates about "when does it begin?", are misplaced and meaningless, in part because "consciousness" as a word has many valid and interestin...
biology
5,210
Brain neurons as quantum computers: {\it in vivo} support of background physics
q-bio.NC
The question: whether quantum coherent states can sustain decoherence, heating and dissipation over time scales comparable to the dynamical timescales of the brain neurons, is actively discussed in the last years. Positive answer on this question is crucial, in particular, for consideration of brain neurons as quantum ...
biology
5,211
Ocular dominance patterns and the wire length minimization: a numerical study
q-bio.NC
We study a mathematical model for ocular dominance patterns (ODPs) in primary visual cortex. This model is based on the premise that ODP is an adaptation to minimize the length of intra-cortical wiring. Thus we attempt to understand the existing ODPs by solving a wire length minimization problem. We divide all the neur...
biology
5,212
Comparation based bottom-up and top-down filtering model of the hippocampus and its environment
q-bio.NC
Two rate code models -- a reconstruction network model and a control model -- of the hippocampal-entorhinal loop are merged. The hippocampal-entorhinal loop plays a double role in the unified model, it is part of a reconstruction network and a controller, too. This double role turns the bottom-up information flow into ...
biology
5,213
Fast Computation with Neural Oscillators
q-bio.NC
Artificial spike-based computation, inspired by models of computations in the central nervous system, may present significant performance advantages over traditional methods for specific types of large scale problems. In this paper, we study new models for two common instances of such computation, winner-take-all and c...
biology
5,214
Random Walks for Spike-Timing Dependent Plasticity
q-bio.NC
Random walk methods are used to calculate the moments of negative image equilibrium distributions in synaptic weight dynamics governed by spike-timing dependent plasticity (STDP). The neural architecture of the model is based on the electrosensory lateral line lobe (ELL) of mormyrid electric fish, which forms a negativ...
biology
5,215
K-Winners-Take-All Computation with Neural Oscillators
q-bio.NC
Artificial spike-based computation, inspired by models of computation in the central nervous system, may present significant performance advantages over traditional methods for specific types of large scale problems. This paper describes very simple network architectures for k-winners-take-all and soft-winner-take-all ...
biology
5,216
Graded persisting activity of heterogeneous neuron ensembles subject to white noises
q-bio.NC
Effects of distractions such as noises and parameter heterogeneity have been studied on the firing activity of ensemble neurons, each of which is described by the extended Morris-Lecar model showing the graded persisting firings with the aid of an included ${\rm Ca}^{2+}$-dependent cation current. Although the sustaine...
biology
5,217
Spectra and waiting-time densities in firing resonant and nonresonant neurons
q-bio.NC
The response of a neural cell to an external stimulus can follow one of the two patterns: Nonresonant neurons monotonously relax to the resting state after excitation while resonant ones show subthreshold oscillations. We investigate how do these subthreshold properties of neurons affect their suprathreshold response. ...
biology
5,218
Quantum Physics in Neuroscience and Psychology: A New Theory With Respect to Mind/Brain Interaction
q-bio.NC
The cognitive frame in which most neuropsychological research on the neural basis of behavior is conducted contains the assumption that brain mechanisms per se fully suffice to explain all psychologically described phenomena. This assumption stems from the idea that the brain is made up entirely of material particles a...
biology
5,219
Response variability in balanced cortical networks
q-bio.NC
We study the spike statistics of neurons in a network with dynamically balanced excitation and inhibition. Our model, intended to represent a generic cortical column, comprises randomly connected excitatory and inhibitory leaky integrate-and-fire neurons, driven by excitatory input from an external population. The high...
biology
5,220
Mean field methods for cortical network dynamics
q-bio.NC
We review the use of mean field theory for describing the dynamics of dense, randomly connected cortical circuits. For a simple network of excitatory and inhibitory leaky integrate-and-fire neurons, we can show how the firing irregularity, as measured by the Fano factor, increases with the strength of the synapses in t...
biology
5,221
High conductance states in a mean field cortical network model
q-bio.NC
Measured responses from visual cortical neurons show that spike times tend to be correlated rather than exactly Poisson distributed. Fano factors vary and are usually greater than 1 due to the tendency of spikes being clustered into bursts. We show that this behavior emerges naturally in a balanced cortical network mod...
biology
5,222
Fine Discrimination of Analog Patterns by Nonlinear Dendritic Inhibition
q-bio.NC
Recent experiments revealed that a certain class of inhibitory neurons in the cerebral cortex make synapses not onto cell bodies but at distal parts of dendrites of the target neurons, mediating highly nonlinear dendritic inhibition. We propose a novel form of competitive neural network model that realizes such dendrit...
biology
5,223
Performance of networks of artificial neurons: The role of clustering
q-bio.NC
The performance of the Hopfield neural network model is numerically studied on various complex networks, such as the Watts-Strogatz network, the Barab{\'a}si-Albert network, and the neuronal network of the C. elegans. Through the use of a systematic way of controlling the clustering coefficient, with the degree of each...
biology
5,224
The perception of melodic consonance: an acoustical and neurophysiological explanation based on the overtone series
q-bio.NC
The melodic consonance of a sequence of tones is explained using the overtone series: the overtones form "flow lines" that link the tones melodically; the strength of these flow lines determines the melodic consonance. This hypothesis admits of psychoacoustical and neurophysiological interpretations that fit well with ...
biology
5,225
Mean field theory for a balanced hypercolumn model of orientation selectivity in primary visual cortex
q-bio.NC
We present a complete mean field theory for a balanced state of a simple model of an orientation hypercolumn. The theory is complemented by a description of a numerical procedure for solving the mean-field equations quantitatively. With our treatment, we can determine self-consistently both the firing rates and the fir...
biology
5,226
Pulse-coupled resonate-and-fire models
q-bio.NC
We analyze two pulse-coupled resonate-and-fire neurons. Numerical simulation reveals that an anti-phase state is an attractor of this model. We can analytically explain the stability of anti-phase states by means of a return map of firing times, which we propose in this paper. The resultant stability condition turns ou...
biology
5,227
A toy model of the brain
q-bio.NC
We have designed a toy brain and have written computer code that simulates it. This toy brain is flexible, modular, has hierarchical learning and recognition, has short and long term memory, is distributed (i.e. has no central control), is asynchronous, and includes parallel and series processing. We have simulated the...
biology
5,228
General representation of collective neural dynamics with columnar modularity
q-bio.NC
We exhibit a mathematical framework to represent the neural dynamics at cortical level. Our description of neural dynamics with columnar and functional modularity, named fibre bundle representation (FBM) method, is based both on neuroscience and informatics, whereas they correspond with the conventional formulas in sta...
biology
5,229
Cortical Dynamics and Awareness State: An Interpretation of Observed Interstimulus Interval Dependence in Apparent Motion
q-bio.NC
In a recent paper on Cortical Dynamics, Francis and Grossberg raise the question how visual forms and motion information are integrated to generate a coherent percept of moving forms? In their investigation of illusory contours (which are, like Kanizsa squares, mental constructs rather than stimuli on the retina) they ...
biology
5,230
Predicting spike times of a detailed conductance-based neuron model driven by stochastic spike arrival
q-bio.NC
Reduced models of neuronal activity such as Integrate-and-Fire models allow a description of neuronal dynamics in simple, intuitive terms and are easy to simulate numerically. We present a method to fit an Integrate-and-Fire-type model of neuronal activity, namely a modified version of the Spike Response Model, to a de...
biology
5,231
A subjective distance between stimuli: quantifying the metric structure of representations
q-bio.NC
As subjects perceive the sensory world, different stimuli elicit a number of neural representations. Here, a subjective distance between stimuli is defined, measuring the degree of similarity between the underlying representations. As an example, the subjective distance between different locations in space is calculate...
biology
5,232
How to compute using globally coupled oscillators
q-bio.NC
Synchronization is known to play a vital role within many highly connected neural systems such as the olfactory systems of fish and insects. In this paper we show how one can robustly and effectively perform practical computations using small perturbations to a very simple globally coupled network of coupled oscillator...
biology
5,233
Can Neural Networks Recognize Parts?
q-bio.NC
We have demonstrated neural networks can recognize parts by visual images. Input signals are gray scale photographs of objects consisting of some parts and output signals are their shapes. By training neural networks by a few set of images, without any supervision they become to be able to recognize the boundary betwee...
biology
5,234
Theory of localized synfire chain
q-bio.NC
Neuron is a noisy information processing unit and conventional view is that information in the cortex is carried on the rate of neurons spike emission. More recent studies on the activity propagation through the homogeneous network have demonstrated that signals can be transmitted with millisecond fidelity; this model ...
biology
5,235
Stimulus competition by inhibitory interference
q-bio.NC
When two stimuli are present in the receptive field of a V4 neuron, the firing rate response is between the weakest and strongest response elicited by each of the stimuli alone (Reynolds et al, 1999, Journal of Neuroscience 19:1736-1753). When attention is directed towards the stimulus eliciting the strongest response ...
biology
5,236
Effect of Synchronous Incoming Spikes on Activity Pattern in A Network of Spiking Neurons
q-bio.NC
Although recent neurophysiological experiments suggest that synchronous neural activity is involved in some perceptual and cognitive processes, the functional role of such coherent neuronal behavior is not well understood. As a first step in clarifying this role, we investigate how the temporal coherence of certain neu...
biology
5,237
Neurokinematic Modeling of Complex Swimming Patterns of the Larval Zebrafish
q-bio.NC
Larval zebrafish exhibit a variety of complex undulatory swimming patterns. This repertoire is controlled by the 300 neurons projecting from brain into spinal cord. Understanding how descending control signals shape the output of spinal circuits, however, is nontrivial. We have therefore developed a segmental oscillato...
biology
5,238
Activity-dependent brain model explaining EEG spectra
q-bio.NC
Most brain models focus on associative memory or calculation capability, experimentally inaccessible using physiological methods. Here we present a model explaining a basic feature of electroencephalograms (EEG). Our model is based on an electrical network with threshold firing and plasticity of synapses that reproduce...
biology
5,239
Cognitive styles sex the brain, compete neurally, and quantify deficits in autism
q-bio.NC
Introduction: Two key dimensions of the mind are understanding and responding to another's mental state (empathizing), and analysing lawful behaviour (systemizing). Methods: Two questionnaires, the Systemizing Quotient (SQ) and the Empathy Quotient (EQ), were administered to a normal control group and a group of indi...
biology
5,240
Computational Models of Adult Neurogenesis
q-bio.NC
Experimental results in recent years have shown that adult neurogenesis is a significant phenomenon in the mammalian brain. Little is known, however, about the functional role played by the generation and destruction of neurons in the context of and adult brain. Here we propose two models where new projection neurons a...
biology
5,241
Comment on: "Characterization of subthreshold voltage fluctuations in neuronal membranes" by M. Rudolph and A. Destexhe
q-bio.NC
In two recent papers, Rudolph and Destexhe (Neural Comp. {\bf 15}, 2577-2618, 2003; Neural Comp. in press, 2005) studied a leaky integrator model (i.e. an RC-circuit) driven by correlated (``colored'') Gaussian conductance noise and Gaussian current noise. In the first paper they derived an expression for the station...
biology
5,242
Autoassociative Memory Retrieval and Spontaneous Activity Bumps in Small-World Networks of Integrate-and-Fire Neurons
q-bio.NC
Qualitatively, some real networks in the brain could be characterized as 'small worlds', in the sense that the structure of their connections is intermediate between the extremes of an orderly geometric arrangement and of a geometry-independent random mesh. Small worlds can be defined more precisely in terms of their m...
biology
5,243
Transient Information Flow in a Network of Excitatory and Inhibitory Model Neurons: Role of Noise and Signal Autocorrelation
q-bio.NC
We investigate the performance of sparsely-connected networks of integrate-and-fire neurons for ultra-short term information processing. We exploit the fact that the population activity of networks with balanced excitation and inhibition can switch from an oscillatory firing regime to a state of asynchronous irregular ...
biology
5,244
Signal buffering in random networks of spiking neurons: microscopic vs. macroscopic phenomena
q-bio.NC
In randomly connected networks of pulse-coupled elements a time-dependent input signal can be buffered over a short time. We studied the signal buffering properties in simulated networks as a function of the networks state, characterized by both the Lyapunov exponent of the microscopic dynamics and the macroscopic acti...
biology
5,245
Optimal Spike-Timing Dependent Plasticity for Precise Action Potential Firing
q-bio.NC
In timing-based neural codes, neurons have to emit action potentials at precise moments in time. We use a supervised learning paradigm to derive a synaptic update rule that optimizes via gradient ascent the likelihood of postsynaptic firing at one or several desired firing times. We find that the optimal strategy of up...
biology
5,246
Inhibitory synchrony as a mechanism for attentional gain modulation
q-bio.NC
Recordings from area V4 of monkeys have revealed that when the focus of attention is on a visual stimulus within the receptive field of a cortical neuron, two distinct changes can occur: The firing rate of the neuron can change and there can be an increase in the coherence between spikes and the local field potential i...
biology
5,247
Features and dimensions: Motion estimation in fly vision
q-bio.NC
We characterize the computation of motion in the fly visual system as a mapping from the high dimensional space of signals in the retinal photodetector array to the probability of generating an action potential in a motion sensitive neuron. Our approach to this problem identifies a low dimensional subspace of signals w...
biology
5,248
Noise-enhanced computation in a model of a cortical column
q-bio.NC
Varied sensory systems use noise in order to enhance detection of weak signals. It has been conjectured in the literature that this effect, known as stochastic resonance, may take place in central cognitive processes such as the memory retrieval of arithmetical multiplication. We show in a simplified model of cortical ...
biology
5,249
Wiring cost in the organization of a biological network
q-bio.NC
To find out the role of the wiring cost in the organization of the neural network of the nematode \textit{Caenorhapditis elegans} (\textit{C. elegans}), we build the neuronal map of \textit{C. elegans} based on geometrical positions of neurons and define the cost as inter-neuronal Euclidean distance \textit{d}. We show...
biology
5,250
Dynamics of learning in coupled oscillators tutored with delayed reinforcements
q-bio.NC
In this work we analyze the solutions of a simple system of coupled phase oscillators in which the connectivity is learned dynamically. The model is inspired in the process of learning of birdsong by oscine birds. An oscillator acts as the generator of a basic rhythm, and drives slave oscillators which are responsible ...
biology
5,251
Search for optimal measure for discriminating spike trains with different randomness
q-bio.NC
We wish to discriminate spike sequences based on the degree of irregularity. For this purpose, we search for a rational expressions of quadratic functions of consecutive interspike intervals that efficiently measures spiking irregularity. Under natural assumptions, the functional form of the coefficient can be paramete...
biology
5,252
Postsynaptic mechanisms for the induction of long-term potentiation and long-term depression of synaptic transmission in CA1 pyramidal neurons of the hippocampus
q-bio.NC
The studies described in this dissertation have attempted to address the cellular mechanisms of information storage by the brain. My work has focused primarily on the postsynaptic events that occur during and after induction of long-term potentiation (LTP) and long-term depression (LTD) at the Schaffer collateral-CA1 s...
biology
5,253
Traveling wave solutions of Fitzhugh model with cross-diffusion
q-bio.NC
The Fitzhugh-Nagumo equations have been used as a caricature of the Hodgkin-Huxley equations of neuron firing to better understand the essential dynamics of the interaction of the membrane potential and the restoring force and to capture, qualitatively, the general properties of an excitable membrane. Even though its s...
biology
5,254
Nonlinear aspects of the EEG during sleep in children
q-bio.NC
Electroencephalograph (EEG) analysis enables the neuronal behavior of a section of the brain to be examined. If the behavior is nonlinear then nonlinear tools can be used to glean information on brain behavior, and aid in the diagnosis of sleep abnormalities such as obstructive sleep apnea syndrome (OSAS). In this pape...
biology
5,255
Effects of fast presynaptic noise in attractor neural networks
q-bio.NC
We study both analytically and numerically the effect of presynaptic noise on the transmission of information in attractor neural networks. The noise occurs on a very short-time scale compared to that for the neuron dynamics and it produces short-time synaptic depression. This is inspired in recent neurobiological find...
biology
5,256
Stimulus - response curves of a neuronal model for noisy subthreshold oscillations and related spike generation
q-bio.NC
We investigate the stimulus-dependent tuning properties of a noisy ionic conductance model for intrinsic subthreshold oscillations in membrane potential and associated spike generation. On depolarization by an applied current, the model exhibits subthreshold oscillatory activity with occasional spike generation when os...
biology
5,257
Control of neural chaos by synaptic noise
q-bio.NC
We studied neural automata -or neurobiologically inspired cellular automata- which exhibits chaotic itinerancy among the different stored patterns or memories. This is a consequence of activity-dependent synaptic fluctuations, which continuously destabilize the attractor and induce irregular hopping to other possible a...
biology
5,258
Participatory Ecosystem Management Planning at Tuzla Lake (Turkey) Using Fuzzy Cognitive Mapping
q-bio.NC
A participatory environmental management plan was prepared for Tuzla Lake, Turkey. Fuzzy cognitive mapping approach was used to obtain stakeholder views and desires. Cognitive maps were prepared with 44 stakeholders (villagers, local decisionmakers, government and non-government organization (NGO) officials). Graph the...
biology
5,259
Context-dependent selection of visuomotor maps
q-bio.NC
Behavior results from the integration of ongoing sensory signals and contextual information in various forms, such as past experience, expectations, current goals, etc. Thus, the response to a specific stimulus, say the ringing of a doorbell, varies depending on whether you are at home or in someone else's house. What ...
biology
5,260
Stable Concurrent Synchronization in Dynamic System Networks
q-bio.NC
In a network of dynamical systems, concurrent synchronization is a regime where multiple groups of fully synchronized elements coexist. In the brain, concurrent synchronization may occur at several scales, with multiple ``rhythms'' interacting and functional assemblies combining neural oscillators of many different typ...
biology
5,261
Temporal correlation based learning in neuron models
q-bio.NC
We study a learning rule based upon the temporal correlation (weighted by a learning kernel) between incoming spikes and the internal state of the postsynaptic neuron, building upon previous studies of spike timing dependent synaptic plasticity (\cite{KGvHW,KGvH1,vH}). Our learning rule for the synaptic weight $w_{ij}$...
biology
5,262
Attentional modulation of firing rate and synchrony in a model cortical network
q-bio.NC
When attention is directed into the receptive field of a V4 neuron, its contrast response curve is shifted to lower contrast values (Reynolds et al, 2000, Neuron 26:703). Attention also increases the coherence between neurons responding to the same stimulus (Fries et al, 2001, Science 291:1560). We studied how the firi...
biology
5,263
Contextual Emergence of Mental States from Neurodynamics
q-bio.NC
The emergence of mental states from neural states by partitioning the neural phase space is analyzed in terms of symbolic dynamics. Well-defined mental states provide contexts inducing a criterion of structural stability for the neurodynamics that can be implemented by particular partitions. This leads to distinguished...
biology
5,264
Waveform sample method of excitable sensory neuron
q-bio.NC
We present a new interpretation for encoding information of the period of input signals into spike-trains in individual sensory neuronal systems. The spike-train could be described as the waveform sample of the input signal which locks sample points to wave crests with randomness. Based on simulations of the Hodgkin-Hu...
biology
5,265
Sleep as the solution to an optimization problem
q-bio.NC
This paper develops a highly simplified model with which to analyze the phenomenon of sleep. Motivated by Crick's suggestion that sleep is the brain's way of ``taking out the trash,'' a suggestion that is supported by emerging evidence, we consider the problem of the filling and emptying of a tank. At any given time, t...
biology
5,266
Glial activation in white matter following ischemia in the neonatal P7 rat brain
q-bio.NC
This study examines cell death and proliferation in the white matter after neonatal stroke. In post-natal day 7 injured rat, there was a marked reduction in myelin basic protein (MBP) immunostaining mainly corresponding to numerous pyknotic immature oligodendrocytes and TUNEL-positive astrocytes in the ipsilateral exte...
biology
5,267
Gradient learning in spiking neural networks by dynamic perturbation of conductances
q-bio.NC
We present a method of estimating the gradient of an objective function with respect to the synaptic weights of a spiking neural network. The method works by measuring the fluctuations in the objective function in response to dynamic perturbation of the membrane conductances of the neurons. It is compatible with recurr...
biology
5,268
Self-Organized Criticality model for Brain Plasticity
q-bio.NC
Networks of living neurons exhibit an avalanche mode of activity, experimentally found in organotypic cultures. Here we present a model based on self-organized criticality and taking into account brain plasticity, which is able to reproduce the spectrum of electroencephalograms (EEG). The model consists in an electrica...
biology
5,269
Concurrent encoding of frequency and amplitude modulation in human auditory cortex: MEG evidence
q-bio.NC
A natural sound can be described by dynamic changes in envelope (amplitude) and carrier (frequency), corresponding to amplitude modulation (AM) and frequency modulation (FM) respectively. Although the neural responses to both AM and FM sounds are extensively studied in both animals and humans, it is uncertain how they ...
biology
5,270
Grandmother cells and the storage capacity of the human brain
q-bio.NC
Quian Quiroga et al. [Nature 435, 1102 (2005)] have recently discovered neurons that appear to have the characteristics of grandmother (GM) cells. Here we quantitatively assess the compatibility of their data with the GM-cell hypothesis. We show that, contrary to the general impression, a GM-cell representation can be ...
biology
5,271
Synchronization in Electrically Coupled Neural Networks
q-bio.NC
In this report, we investigate the synchronization of temporal activity in an electrically coupled neural network model. The electrical coupling is established by homotypic static gap-junctions (Connexin 43). Two distinct network topologies, namely: {\em sparse random network, (SRN)} and {\em fully connected network, (...
biology
5,272
Algorithms for identification and categorization
q-bio.NC
The main features of a family of efficient algorithms for recognition and classification of complex patterns are briefly reviewed. They are inspired in the observation that fast synaptic noise is essential for some of the processing of information in the brain.
biology
5,273
Competition between synaptic depression and facilitation in attractor neural networks
q-bio.NC
We study the effect of competition between short-term synaptic depression and facilitation on the dynamical properties of attractor neural networks, using Monte Carlo simulation and a mean field analysis. Depending on the balance between depression, facilitation and the noise, the network displays different behaviours,...
biology
5,274
Chaotic hopping between attractors in neural networks
q-bio.NC
We present a neurobiologically--inspired stochastic cellular automaton whose state jumps with time between the attractors corresponding to a series of stored patterns. The jumping varies from regular to chaotic as the model parameters are modified. The resulting irregular behavior, which mimics the state of attention i...
biology
5,275
Instability of attractors in autoassociative networks with bioinspired fast synaptic noise
q-bio.NC
We studied autoassociative networks in which synapses are noisy on a time scale much shorter that the one for the neuron dynamics. In our model a presynaptic noise causes postsynaptic depression as recently observed in neurobiological systems. This results in a nonequilibrium condition in which the network sensitivity ...
biology
5,276
Combinatorial on/off Model for Olfactory Coding
q-bio.NC
We present a model for olfactory coding based on spatial representation of glomerular responses. In this model distinct odorants activate specific subsets of glomeruli, dependent upon the odorant's chemical identity and concentration. The glomerular response specificities are understood statistically, based on experime...
biology
5,277
Synaptic plasticity of Inhibitory synapse promote synchrony in inhibitory network in presence of heterogeneity and noise
q-bio.NC
Recently spike timing dependent plasticity was observed in inhibitory synapse in the layer II of entorhinal cortex. The rule provides an interesting zero in the region of $\Delta t=t_{post}-t_{pre}=0$ and in addition the dynamic range of the rule lie in gamma frequency band. We propose a robust mechanism based on this ...
biology
5,278
The role of synaptic facilitation in coincidence spike detection
q-bio.NC
Using a realistic model of activity dependent dynamical synapses and a standard integrate and fire neuron model we study, both analytically and numerically, the conditions in which a postsynaptic neuron efficiently detects temporal coincidences of spikes arriving at certain frequency from N different afferents. We exte...
biology
5,279
Chaotic itinerancy, temporal segmentation and spatio-temporal combinatorial codes
q-bio.NC
We study a deterministic dynamics with two time scales in a continuous state attractor network. To the usual (fast) relaxation dynamics towards point attractors (``patterns'') we add a slow coupling dynamics that makes the visited patterns to loose stability leading to an itinerant behavior in the form of punctuated eq...
biology
5,280
Stable Propagation of a Burst Through a One-Dimensional Homogeneous Excitatory Chain Model of Songbird Nucleus HVC
q-bio.NC
We demonstrate numerically that a brief burst consisting of two to six spikes can propagate in a stable manner through a one-dimensional homogeneous feedforward chain of non-bursting neurons with excitatory synaptic connections. Our results are obtained for two kinds of neuronal models, leaky integrate-and-fire (LIF) n...
biology
5,281
Episodic synchronization in dynamically driven neurons
q-bio.NC
We examine the response of type II excitable neurons to trains of synaptic pulses, as a function of the pulse frequency and amplitude. We show that the resonant behavior characteristic of type II excitability, already described for harmonic inputs, is also present for pulsed inputs. With this in mind, we study the resp...
biology
5,282
Theory of Interaction of Memory Patterns in Layered Associative Networks
q-bio.NC
A synfire chain is a network that can generate repeated spike patterns with millisecond precision. Although synfire chains with only one activity propagation mode have been intensively analyzed with several neuron models, those with several stable propagation modes have not been thoroughly investigated. By using the le...
biology
5,283
A new stimulus approach in the search for biological nonlocality
q-bio.NC
Preliminary research in the area of biophysics appears to indicate the existence of quantum entanglement and nonlocality at the biological level, both for human subjects and for neurons derived from human neural stem cells. The lack of clear and replicable findings, especially where human subjects are concerned, result...
biology
5,284
Neural integrator - a sandpile model
q-bio.NC
We investigated a model for the neural integrator based on hysteretic units connected by positive feedback. Hysteresis is assumed to emerge from the intrinsic properties of the cells. We consider the recurrent networks containing either bistable or multistable neurons. We apply our analysis to the oculomotor velocity-t...
biology
5,285
Triangular lattice neurons may implement an advanced numeral system to precisely encode rat position over large ranges
q-bio.NC
We argue by observation of the neural data that neurons in area dMEC of rats, which fire whenever the rat is on any vertex of a regular triangular lattice that tiles 2-d space, may be using an advanced numeral system to reversibly encode rat position. We interpret measured dMEC properties within the framework of a resi...
biology
5,286
Scaling law for the transient behavior of type-II neuron models
q-bio.NC
We study the transient regime of type-II biophysical neuron models and determine the scaling behavior of relaxation times $\tau$ near but below the repetitive firing critical current, $\tau \simeq C (I_c-I)^{-\Delta}$. For both the Hodgkin-Huxley and Morris-Lecar models we find that the critical exponent is independent...
biology
5,287
Perception proximale et distale à l'aide du dispositif de Lenay
q-bio.NC
We present in this article experimental results obtained with the "dispositif de Lenay" : for a localization task (distal perception) and an orientation estimation task (proximal perception of the orientation of a cylinder in a plane). In this last experiment, a "virtual" version of the Lenay device was used. Results a...
biology
5,288
Cerebellar Purkinje Cell Loss in Heterozygous Rora+/-Mice: A Longitudinal Study
q-bio.NC
The staggerer (sg/sg) mutation is a spontaneous deletion in the Rora gene that prevents the translation of the ligand-binding domain (LBD), leading to the loss of ROR\alpha activity. The homozygous Rorasg/sg mutant mouse, whose most obvious phenotype is ataxia associated with cerebellar degeneration, also displays a va...
biology
5,289
Pushing it to the Limit: Adaptation With Dynamically Switching Gain Control
q-bio.NC
With this paper we propose a model to simulate the functional aspects of light adaptation in retinal photoreceptors. Our model, however, does not link specific stages to the detailed molecular processes which are thought to mediate adaptation in real photoreceptors. We rather model the photoreceptor as a self-adjusting...
biology
5,290
Activity-dependent self-wiring is a basis of structural plastisity in neural networks
q-bio.NC
Dynamical wiring and rewiring in neural networks are carried out by activity-dependent growth and retraction of axons and dendrites, guided by gudance molecules, released by target cells. Experience-dependent structural changes in cortical microcurcuts lead to changes in activity, i.e. to changes in information encoded...
biology
5,291
Structural network heterogeneities and network dynamics: a possible dynamical mechanism for hippocampal memory reactivation
q-bio.NC
The hippocampus has the capacity for reactivating recently acquired memories [1-3] and it is hypothesized that one of the functions of sleep reactivation is the facilitation of consolidation of novel memory traces [4-11]. The dynamic and network processes underlying such a reactivation remain, however, unknown. We show...
biology
5,292
Unbalanced synaptic inhibition can create intensity-tuned auditory cortex neurons
q-bio.NC
Intensity-tuned auditory cortex neurons may be formed by intensity-tuned synaptic excitation. Synaptic inhibition has also been shown to enhance, and possibly even create intensity-tuned neurons. Here we show, using in vivo whole cell recordings in pentobarbital-anesthetized rats, that some intensity-tuned neurons are ...
biology
5,293
Learning with incomplete information - and the mathematical structure behind it
q-bio.NC
Learning and the ability to learn are important factors in development and evolutionary processes [1]. Depending on the level, the complexity of learning can strongly vary. While associative learning can explain simple learning behaviour [1,2] much more sophisticated strategies seem to be involved in complex learning t...
biology
5,294
Searching for memories, Sudoku, implicit check-bits, and the iterative use of not-always-correct rapid neural computation
q-bio.NC
The algorithms that simple feedback neural circuits representing a brain area can rapidly carry out are often adequate to solve only easy problems, and for more difficult problems can return incorrect answers. A new excitatory-inhibitory circuit model of associative memory displays the common human problem of failing t...
biology
5,295
Calculating event-triggered average synaptic conductances from the membrane potential
q-bio.NC
The optimal patterns of synaptic conductances for spike generation in central neurons is a subject of considerable interest. Ideally, such conductance time courses should be extracted from membrane potential (Vm) activity, but this is difficult because the nonlinear contribution of conductances to the Vm renders their ...
biology
5,296
The Hilbert transform of horizontal gaze position during natural image classification by saccades
q-bio.NC
Eye movements are a behavioral response that can be involved in tasks as complicated as natural image classification. This report confirms that pro- and anti-saccades can be used by a volunteer to designate target (animal) or non-target images that were centered 16 degrees off the fixation point. With more than 86% cor...
biology
5,297
Toward an adequate mathematical model of mental space: conscious/unconscious dynamics on $m$-adic trees
q-bio.NC
We try to perform geometrization of cognitive science and psychology by representing information states of cognitive systems by points of {\it mental space} given by a hierarchic $m$-adic tree. Associations are represented by balls and ideas by collections of balls. We consider dynamics of ideas based on lifting of dyn...
biology
5,298
Correlation entropy of synaptic input-output dynamics
q-bio.NC
The responses of synapses in the neocortex show highly stochastic and nonlinear behavior. The microscopic dynamics underlying this behavior, and its computational consequences during natural patterns of synaptic input, are not explained by conventional macroscopic models of deterministic ensemble mean dynamics. Here, w...
biology
5,299
Brain, Music and non-Poisson Renewal Processes
q-bio.NC
In this paper we show that both music composition and brain function, as revealed by the Electroencephalogram (EEG) analysis, are renewal non-Poisson processes living in the non-ergodic dominion. To reach this important conclusion we process the data with the minimum spanning tree method, so as to detect significant ev...
biology