section_summaries sequencelengths 1 17 | abstract stringlengths 18 2.93k |
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"overall , neuropsychiatric symptoms in pd have been shown to be negatively associated with cognitive performance .",
"although anxiety and depression are often related and coexist in pd patients , recent research suggests that anxiety rather than depression is the most prominent and prevalent mood disord... | research on the implications of anxiety in parkinson 's disease ( pd ) has been neglected despite its prevalence in nearly 50% of patients and its negative impact on quality of life . previous reports have noted that neuropsychiatric symptoms impair cognitive performance in pd patients ; however , to date , no study ha... |
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"as small non - coding rnas regulate gene expression and tumorigenesis , they may represent a novel cancer therapy .",
"mirnas regulate a broad range of biological processes including timing of development , cell cycle progression , stem cell self - renewal , differentiation , cancer initiation , cancer c... | small non - coding rnas include sirna , mirna , pirna and snorna . the involvement of mirnas in the regulation of mammary gland tumorigenesis has been widely studied while the role for other small non - coding rnas remains unclear . here we summarize the involvement of mirna in breast cancer onset and progression throu... |
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"the aim of the current study was to evaluate the role of the pigtail catheter drainage in outpatient management of patients with early onset severe ohss .",
"in this study we established the efficacy and safety of pigtail catheter drainage in the management of severe / critical ohss in patients who under... | objective : to evaluate the efficacy and safety of outpatient management of severe ovarian hyperstimulation syndrome ( ohss ) requiring placement of a pigtail catheter.methods : retrospective analysis of thirty - three consecutive patients who underwent in - vitro fertilization ( 2003 - 2009 ) and developed severe / ... |
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"congenital adrenal hyperplasia ( cah ) refers to a group of autosomal recessive disorders caused by an enzyme deficiency which leads to defects in biosynthesis of steroid precursors .",
"however , the non classical cah variant is more common with a prevalence rate of 1 in 1000 .",
"depending on the s... | congenital adrenal hyperplasia is a group of autosomal recessive disorders caused by enzyme deficiency which leads to defects in biosynthesis of steroid precursors . most common is 21 hydroxylase deficiency . clinical spectrum varies from non - classical cah to classic cah , and it may be simple virilising form or salt... |
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", we hypothesized that pentoxifylline , due to its anti - inflammatory and immunosuppressive activity , may affect autoimmune diabetes .",
"consequently , we decided to investigate whether pentoxifylline treatment could prevent the development of mlds - induced diabetes in mice .",
"it has been shown... | objective(s):pentoxifylline is an immunomodulatory and anti - inflammatory agent and is used in vascular disorders . it has been shown that pentoxifylline inhibits proinflammatory cytokines production . the purpose of this study was to investigate the therapeutic effects of pentoxifylline on the treatment of autoimmune... |
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"determinar a presena de anticorpos ige especficos para superantgenos estafiloccicos e o grau de sensibilizao mediada por esses , assim como se esses esto associados gravidade da asma em pacientes adultos ."
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"estudo transversal incluindo asmticos adultos em acompanhamento ambulatorial em um hosp... | abstractobjective : to determine the presence of staphylococcal superantigen - specific ige antibodies and degree of ige - mediated sensitization , as well as whether or not those are associated with the severity of asthma in adult patients . methods : this was a cross - sectional study involving outpatients with asthm... |
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"the purpose of the study was to determine the effectiveness of nursing interventions based on family needs on family satisfaction level of hospitalized patients in the neurosurgery intensive care unit of al - zahra hospital in 2010 .",
"the aim of this study was to analyze the satisfaction of the familie... | background : since the family is a social system , the impairment in each of its component members may disrupt the entire family system . one of the stress sources for families is accidents leading to hospitalization particularly in the intensive care unit ( icu ) . in many cases , the families needs in patient care ar... |
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"accordingly , the objective of the present study is to examine the impact of peplau therapeutic communication model on anxiety and depression in patients who were candidate for coronary bypass surgery .",
"coronary artery disease is the most cardiovascular disorder as a health problem in developing and d... | background and objective : anxiety and depression are among the psychological disorders in heart
surgeries . establishing a simple communication is essential to reduce anxiety and depression . hence , the objective of the present studywas to examine the impact of peplau therapeutic communication model on anxiety an... |
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"antigenic analysis of select isolates was performed at the centers for disease control and prevention ( cdc ) in atlanta , georgia , by using the hemagglutination inhibition ( hi ) assay and postinfection ferret antisera ( 11 ) .",
"sixty - four patients in nepal that met us department of defense enrollm... | worldwide emergence of variant viruses has prompted a change in the 20052006 h3n2 influenza a vaccine strain . |
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"the aim of this paper is to investigate differences in how obesity relates to indicators of physiological dysregulation in men and women of diverse populations .",
"we examine how elevated weight and obesity ( using an indicator that considers both bmi and waist circumference ) relate to having levels de... | excess weight has generally been associated with adverse health outcomes ; however , the link between overweight and health outcomes may vary with socioeconomic , cultural , and epidemiological conditions . we examine associations of weight with indicators of biological risk in three nationally representative populatio... |
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"male macroprolactinomas ( mprl ) are usually revealed by headaches , visual troubles and gonadal insufficiency .",
"however , in some very rare cases it can be a primary presentation or appear after radiotherapy or medical treatment used for tumors destroying the sellar floor and/or the skull base .",
... | background : suppurative meningitis ( sm ) or bacterial meningitis is a life - threatening condition , which is exceptionally due to pituitary tumors ( pt ) . our aim was to analyze its frequency among male macroprolactinomas ( mprl ) deemed to be aggressive , to report the cases we observed in our practice and describ... |
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"we report a series of 300 patients operated for lumbar dissectomy by destandau endospine system .",
"many studies have not been reported in literature for lumbar discectomy by destandau endospine system ."
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"a total of 300 patients suffering from lumbar disc herniations were operated between ... | background : posterior endoscopic discectomy is an established method for treatment of lumbar disc herniation . many studies have not been reported in literature for lumbar discectomy by destandau endospine system . we report a series of 300 patients operated for lumbar dissectomy by destandau endospine system.material... |
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"this article will draw a conceptual model based on patients source of information , perceived benefits , perceived risks , and medical tourism destination image with available literature that will be helpful to mangers to draw their future course of action for competitive advantage and at the same time fulfi... | background : role of information source , perceived benefits and risks , and destination image has significantly been examined in travel and tourism literature ; however , in medical tourism it is yet to be examined thoroughly . the concept discussed in this article is drawn form well established models in tourism lite... |
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"this review highlights three rtk signaling pathways involved in head and neck squamous cell carcinoma ; egfr , the type 1 insulin - like growth factor receptor ( igf-1r ) and the hepatocyte growth factor ( hgf ) receptor ( met ) .",
"this short review will explore the relative contribution of each signal... | molecular therapeutics for treating epidermal growth factor receptor-(egfr- ) expressing cancers are a specific method for treating cancers compared to general cell loss with standard cytotoxic therapeutics . however , the finding that resistance to such therapy is common in clinical trials now dampens the initial enth... |
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"the second set of cultures was treated with tq ( 0.01 , 0.1 , 1 , and 10 m ) on the eighth div for 4 consecutive days to investigate the effect of tq on the survival of dopaminergic neurons .",
"cultures were treated with 1 m of tq ( a concentration that significantly protected dopaminergic neurons in mp... | objectives : to investigate potential mechanisms mediating the neuroprotective effect of thymoquinone ( tq ) on dopaminergic neurons.methods:this study was conducted in the chemistry and biochemistry institute , university of veterinary medicine , vienna , austria between june and august 2013 . primary cultures were pr... |
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"non - union usually can definitely diagnosed within a year of fracture fixation with the same being achieved within 3 months at times . after non - union has been established , intervention is inevitable .",
"we report a case of non - union of the fracture of the neck of the femur , who refused addition... | fracture of the femoral neck continues to be a vexing clinical and therapeutic challenge for the orthopedic surgeon . the fracture has a propensity for non - union and avascular necrosis . it is a challenge for the orthopedic surgeon to decide when to intervene in a case with non - union where the implant continues to ... |
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"granuloma faciale ( gf ) is an uncommon , benign , inflammatory skin disorder of unknown etiology .",
"we present a patient with multiple lesions of gf and its response to topical tacrolimus .",
"the disease is notoriously resistant to therapies and often tends to relapse when treatment is discontinu... | granuloma faciale ( gf ) is a chronic condition characterized by red - brown plaques with follicular accentuation present usually on the face . we present a case of 35-year - old female with 5 year history of plaques over cheek and extra facial sites consistent with gf and its response to topical tacrolimus . this case... |
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"chronic myelomonocytic leukaemia ( cmmol ) is a rare disease with an incidence of 0.370.72 per 100 000 population . the median age at diagnosis varies between 65 years and 75 years [ 14 ] .",
"the radical treatment is allogeneic stem cell transplantation , although this treatment is unsuitable for most p... | we report a case of chronic myelomonocytic leukaemia ( cmmol ) in a 68-year - old man who developed osteomyelitis of the mandible . at the initial visit , he reported uncontrolled gingival bleeding , despite self - administered haemostasis . he complained of severe pain in the socket , despite potent opioid analgesia .... |
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"in a recent issue of critical care , we presented a series of 13 patients undergoing post - cardiotomy extracorporeal membrane oxygenation ( ecmo ) with bivalirudin - based anticoagulation .",
"however , we think that a word of caution should be added to our recently published experience . owing to its p... | bivalirudin has been proposed as the sole anticoagulant in patients under extracorporeal membrane oxygenation ( ecmo ) or cardiopulmonary bypass . owing to the pharmacodynamic properties of bivalirudin , areas of blood stagnation should be carefully avoided in order to limit the risk of thrombosis . the ecmo circuit ha... |
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"the purpose of this study was to assess lv ejection fraction ( lvef ) using 64-slice as a byproduct of mdct coronary examination and to compare efficacy of technique with 2d - tte in a heterogeneous patient population . also , review the role of mdct lv function with a relation to evolution in the technology... | background : coronary computed tomography angiography ( ccta ) is a frequently performed examination for coronary artery disease . when performed with retrospective gating , there is an opportunity to derive functional parameters of left ventricle utilizing automated software . complementary information , if validated ... |
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"therefore , it was our objective to assess the potential antimicrobial activity of aristolochia bracteolata using a bioassay - guided fractionation , in order to produce pure compound that can act as the lead compound in developing new , safe , and effective drug to replace the use of the harmful crude plant... | a bioassay - guided fractionation of methanol extract of aristolochia bracteolata whole plant was carried out in order to evaluate its antimicrobial activity and to identify the active compounds in this extract . antibacterial and antifungal activities of methanol extract against gram - positive , gram - negative , and... |
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"several infections , particularly infective endocarditis , have been reported to show positive findings on anca tests ; furthermore , their clinical features have been acknowledged to mimic anca - associated vasculitis , which may lead to a misdiagnosis and inappropriate treatment ( 2,3 ) .",
"we herein ... | we herein report an unusual case of an infected descending aortic pseudoaneurysm with luminal pathognomonic oscillating vegetation with serological findings and clinical features mimicking anti - proteinase 3-antineutrophil cytoplasmic antibody - associated vasculitis . the positive blood cultures and imaging findings ... |
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"we explored the relationship between vitamin d and endometriosis in a double - blind , randomized clinical trial looking at the effect of vitamin d supplementation on cessation of pain in proven endometriosis after laparoscopic diagnosis and treatment .",
"endometriosis is a prevalent cause of infertilit... | backgroundendometriosis is a disabling disease of reproductive - age women . dysmenorrhea , dyspareunia , and pelvic pain are the main symptoms of endometriosis . its etiology is not clear . endometriosis may have various causes , including vitamin d deficiency , but its effect is controversial.material/methodsin this ... |
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"the aim of this study was to compare the apical sealing and gap formation of ah \n plus / gutta - percha with epiphany system .",
"the null hypotheses tested were as follows : ( 1 ) there is no \n difference in apical microleakage or ( 2 ) apical gap formation among the experimental \n groups and ( 3 ) t... | objectivethe aim of this study was to compare the correspondence between gap formation and
apical microleakage in root canals filled with epoxy resin - based ( ah plus )
combined or not with resinous primer or with a dimethacrylate - based root canal
sealer ( epiphany ) . material and methodsthirty - nine lower s... |
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"we report a case of pndm caused by a novel p.h186d heterozygous mutation in the kcnj11 gene whose treatment was successfully transitioned from insulin to oral sulfonylurea .",
"encoding the sulfonylurea receptor 1 ( sur1 ) of atp - sensitive potassium ( katp ) channel , which has a key role in insulin se... | permanent neonatal diabetes mellitus refers to diabetes that occurs before the age of 6 months and persists through life . it is a rare disorder affecting one in 0.2 - 0.5 million live births . mutations in the gene kcnj11 , encoding the subunit kir6.2 , and abcc8 , encoding sur1 of the atp - sensitive potassium ( katp... |
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", we aimed to compare the plasma creatinine levels with spot urine il-18 levels following radiocontrast administration .",
"recent studies have reported that urine levels of il-18 ( a pro - inflammatory cytokine ) , kidney injury molecule-1 , and neutrophil gelatinase - associated lipocalin ( ngal ) leve... | radiocontrast administration is an important cause of acute renal failure . in this study , compared the plasma creatinine levels with spot urine il-18 levels following radiocontrast administration . twenty patients ( 11 males , 9 females ) underwent radiocontrast diagnostic and therapeutic - enhanced examinations . th... |
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"given its high biocompatibility and well known safety profile and the anti - adhesive capabilities , ha and its composites represent an attractive , non - antibiotic , option to mitigate the impact of biofilm - related infections in various clinical settings including implant - related infections . aim of th... | living in biofilms is probably the most common condition for bacteria and fungi and biofilm - related infections account for the majority of bacterial infectious diseases worldwide.among others biofilm - related infections , those associated with implanted biomaterials have an enormous and still largely underestimated ... |
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"hence , this short term study was undertaken to detect the incidence of mdr , xdr , and pdr bacterial isolates in a tertiary care hospital of central india .",
" in the last two decades , there were so much increase of infectious diseases that the standard of public health in many parts of the world is e... | background and objective . antimicrobial resistance is now a major challenge to clinicians for treating patients . hence , this short term study was undertaken to detect the incidence of multidrug - resistant ( mdr ) , extensively drug - resistant ( xdr ) , and pandrug - resistant ( pdr ) bacterial isolates in a tertia... |
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