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[ [ "anxiety affects quality of life in those living with parkinson 's disease ( pd ) more so than overall cognitive status , motor deficits , apathy , and depression [ 13 ] .", "although anxiety and depression are often related and coexist in pd patients , recent research suggests that anxiety rather than de...
research on the implications of anxiety in parkinson 's disease ( pd ) has been neglected despite its prevalence in nearly 50% of patients and its negative impact on quality of life . previous reports have noted that neuropsychiatric symptoms impair cognitive performance in pd patients ; however , to date , no study ha...
[ [ "small non - coding rnas are transcribed into mrna but remain untranslated in eukaryotic cells .", "they include sirna ( small interfering rna ) , mirna ( microrna ) , pirna ( piwi - interacting rna ) and snorna ( small nucleolar rna ) .", "mirnas are a class of multifunctional singled - stranded smal...
small non - coding rnas include sirna , mirna , pirna and snorna . the involvement of mirnas in the regulation of mammary gland tumorigenesis has been widely studied while the role for other small non - coding rnas remains unclear . here we summarize the involvement of mirna in breast cancer onset and progression throu...
[ [ "ohss is a serious complication of ovulation induction , occurring in 1 - 10% of in vitro fertilization patients ( rizk and aboulghar , 1991 ; brinsden et al . , 1995 ) .", "this iatrogenic condition has a spectrum of clinical and laboratory manifestations ranging from mild to severe , even life - threat...
objective : to evaluate the efficacy and safety of outpatient management of severe ovarian hyperstimulation syndrome ( ohss ) requiring placement of a pigtail catheter.methods : retrospective analysis of thirty - three consecutive patients who underwent in - vitro fertilization ( 2003 - 2009 ) and developed severe / ...
[ [ "congenital adrenal hyperplasia ( cah ) refers to a group of autosomal recessive disorders caused by an enzyme deficiency which leads to defects in biosynthesis of steroid precursors .", "depending on the severity and degree of 21 hydroxylase deficiency , the clinical spectrum may vary from mild form of n...
congenital adrenal hyperplasia is a group of autosomal recessive disorders caused by enzyme deficiency which leads to defects in biosynthesis of steroid precursors . most common is 21 hydroxylase deficiency . clinical spectrum varies from non - classical cah to classic cah , and it may be simple virilising form or salt...
[ [ "type 1 diabetes ( t1d ) results from the destruction of insulin producing pancreatic cells by a cell specific autoimmune process ( 1 ) . chronic pancreatic inflammation ( insulitis ) and destruction of islet -cells in type 1 diabetes", "is mediated by the immune cells , particularly autoreactive cd4 an...
objective(s):pentoxifylline is an immunomodulatory and anti - inflammatory agent and is used in vascular disorders . it has been shown that pentoxifylline inhibits proinflammatory cytokines production . the purpose of this study was to investigate the therapeutic effects of pentoxifylline on the treatment of autoimmune...
[ [ "determinar a presena de anticorpos ige especficos para superantgenos estafiloccicos e o grau de sensibilizao mediada por esses , assim como se esses esto associados gravidade da asma em pacientes adultos ." ], [ "estudo transversal incluindo asmticos adultos em acompanhamento ambulatorial em um hosp...
abstractobjective : to determine the presence of staphylococcal superantigen - specific ige antibodies and degree of ige - mediated sensitization , as well as whether or not those are associated with the severity of asthma in adult patients . methods : this was a cross - sectional study involving outpatients with asthm...
[ [ "the family is the cornerstone of human social support network and its presence is essential in everyone s life . changes inevitably occur in families with illness and hospitalization of a family member . in other words , among the sources of stress for families are accidents leading to hospitalization partic...
background : since the family is a social system , the impairment in each of its component members may disrupt the entire family system . one of the stress sources for families is accidents leading to hospitalization particularly in the intensive care unit ( icu ) . in many cases , the families needs in patient care ar...
[ [ "development of human societies and industrialization as well as changes in stress sources has changed disease pattern in civilized societies . as a result , the disease pattern has changed from traditional diseases such as infectious diseases and malnutrition to diseases such as heart disease , diabetes , ac...
background and objective : anxiety and depression are among the psychological disorders in heart surgeries . establishing a simple communication is essential to reduce anxiety and depression . hence , the objective of the present studywas to examine the impact of peplau therapeutic communication model on anxiety an...
[ [ "sixty - four patients in nepal that met us department of defense enrollment criteria ( 9 ) for influenzalike illness were evaluated by using onsite rapid influenza tests ( optical immunoassay rapid diagnostic tests , thermo electron corp .", "throat swab specimens were collected within the first 72 hours...
worldwide emergence of variant viruses has prompted a change in the 20052006 h3n2 influenza a vaccine strain .
[ [ "rising levels of obesity are becoming a worldwide phenomenon and are increasingly identified as a health problem across the globe [ 14 ] .", "higher weight has been associated with adverse health indicators and outcomes , including cardiovascular disease [ 512 ] , stroke [ 5 , 13 ] , cognitive and functi...
excess weight has generally been associated with adverse health outcomes ; however , the link between overweight and health outcomes may vary with socioeconomic , cultural , and epidemiological conditions . we examine associations of weight with indicators of biological risk in three nationally representative populatio...
[ [ "male macroprolactinomas ( mprl ) are usually revealed by headaches , visual troubles and gonadal insufficiency .", "suppurative meningitis ( sm ) , a life - threatening condition , is scarcely observed in subjects with macro tumors secreting prolactin ( prl ) and in other pituitary tumors ( pt ) .", ...
background : suppurative meningitis ( sm ) or bacterial meningitis is a life - threatening condition , which is exceptionally due to pituitary tumors ( pt ) . our aim was to analyze its frequency among male macroprolactinomas ( mprl ) deemed to be aggressive , to report the cases we observed in our practice and describ...
[ [ "many studies have not been reported in literature for lumbar discectomy by destandau endospine system .", "we report a series of 300 patients operated for lumbar dissectomy by destandau endospine system ." ], [ "a total of 300 patients suffering from lumbar disc herniations were operated between ...
background : posterior endoscopic discectomy is an established method for treatment of lumbar disc herniation . many studies have not been reported in literature for lumbar discectomy by destandau endospine system . we report a series of 300 patients operated for lumbar dissectomy by destandau endospine system.material...
[ [ "medical tourism is illustrated as occurrence in which individuals travel abroad to receive healthcare services ( 1 ) .", "it is a multi - billion dollar industry and countries like india , thailand , singapore , malaysia , belgium , costa rica , cuba , dubai , hungary , israel , jordan , south africa and...
background : role of information source , perceived benefits and risks , and destination image has significantly been examined in travel and tourism literature ; however , in medical tourism it is yet to be examined thoroughly . the concept discussed in this article is drawn form well established models in tourism lite...
[ [ "squamous cell carcinoma of the head and neck ( hnscc ) is a heterogeneous disease that includes tumors arising from the mucosal epithelial surface of the oral cavity , oropharynx , hypopharynx , and larynx . although these tumors originate within different anatomic sites within the upper aerodigestive tract ...
molecular therapeutics for treating epidermal growth factor receptor-(egfr- ) expressing cancers are a specific method for treating cancers compared to general cell loss with standard cytotoxic therapeutics . however , the finding that resistance to such therapy is common in clinical trials now dampens the initial enth...
[ [ "this in vitro study was conducted in the chemistry and biochemistry institute , university of veterinary medicine , vienna , austria between june and august 2013 in accordance with the guidelines of the european union council ( 86/609/eu ) for the use of laboratory animals .", "the work does not require ...
objectives : to investigate potential mechanisms mediating the neuroprotective effect of thymoquinone ( tq ) on dopaminergic neurons.methods:this study was conducted in the chemistry and biochemistry institute , university of veterinary medicine , vienna , austria between june and august 2013 . primary cultures were pr...
[ [ "the femoral head often leads to healing complications , while the more predictable prosthetic replacements are associated with poorer function and significant complications .", "the treatment of these fractures depends on the age of the patient , fracture displacement , bone quality , timing of surgery a...
fracture of the femoral neck continues to be a vexing clinical and therapeutic challenge for the orthopedic surgeon . the fracture has a propensity for non - union and avascular necrosis . it is a challenge for the orthopedic surgeon to decide when to intervene in a case with non - union where the implant continues to ...
[ [ "granuloma faciale ( gf ) is an uncommon , benign , inflammatory skin disorder of unknown etiology .", "it is characterized by single or multiple , grey - brown or violaceous nodules or plaques primarily occurring on the face and occasionally at extra - facial sites .", "the disease is notoriously res...
granuloma faciale ( gf ) is a chronic condition characterized by red - brown plaques with follicular accentuation present usually on the face . we present a case of 35-year - old female with 5 year history of plaques over cheek and extra facial sites consistent with gf and its response to topical tacrolimus . this case...
[ [ "chronic myelomonocytic leukaemia ( cmmol ) is a rare disease with an incidence of 0.370.72 per 100 000 population . the median age at diagnosis varies between 65 years and 75 years [ 14 ] .", "the radical treatment is allogeneic stem cell transplantation , although this treatment is unsuitable for most p...
we report a case of chronic myelomonocytic leukaemia ( cmmol ) in a 68-year - old man who developed osteomyelitis of the mandible . at the initial visit , he reported uncontrolled gingival bleeding , despite self - administered haemostasis . he complained of severe pain in the socket , despite potent opioid analgesia ....
[ [ "in a recent issue of critical care , we presented a series of 13 patients undergoing post - cardiotomy extracorporeal membrane oxygenation ( ecmo ) with bivalirudin - based anticoagulation .", "after this series , we satisfactorily continued this experience , reaching about 20 patients treated .", "h...
bivalirudin has been proposed as the sole anticoagulant in patients under extracorporeal membrane oxygenation ( ecmo ) or cardiopulmonary bypass . owing to the pharmacodynamic properties of bivalirudin , areas of blood stagnation should be carefully avoided in order to limit the risk of thrombosis . the ecmo circuit ha...
[ [ "global and regional left ventricular ( lv ) functions are well - known indicators of cardiac disease . quantitative values of ventricular volumes and of myocardial mass are independent predictors of morbidity and mortality in patients with coronary artery disease .", "classically , echo has been used to ...
background : coronary computed tomography angiography ( ccta ) is a frequently performed examination for coronary artery disease . when performed with retrospective gating , there is an opportunity to derive functional parameters of left ventricle utilizing automated software . complementary information , if validated ...
[ [ "\n moraxella catarrhalis is a gram - negative , aerobic diplococcus human mucosal pathogen which causes middle ear infections in infants and children [ 13 ] , and it is one of the three major causes of otitis media along with streptococcus pneumonia and haemophilus influenzae . although moraxella catarrhalis...
a bioassay - guided fractionation of methanol extract of aristolochia bracteolata whole plant was carried out in order to evaluate its antimicrobial activity and to identify the active compounds in this extract . antibacterial and antifungal activities of methanol extract against gram - positive , gram - negative , and...
[ [ "anti - neutrophil cytoplasmic antibodies ( ancas ) correlate well with a wide spectrum of vasculitis manifestations , including wegener 's granulomatosis , microscopic polyangiitis , and churg - strauss syndrome , all of which are commonly referred to as anca - associated vasculitis ( 1 ) .", "several in...
we herein report an unusual case of an infected descending aortic pseudoaneurysm with luminal pathognomonic oscillating vegetation with serological findings and clinical features mimicking anti - proteinase 3-antineutrophil cytoplasmic antibody - associated vasculitis . the positive blood cultures and imaging findings ...
[ [ "endometriosis is a prevalent cause of infertility , pelvic pain , dysmenorrhea , and dyspareunia in reproductive - age women .", "its diagnosis is by inspection of the pelvis during laparoscopy . in women with pelvic pain and infertility ,", "endometriosis mimics some autoimmune and malignant disease...
backgroundendometriosis is a disabling disease of reproductive - age women . dysmenorrhea , dyspareunia , and pelvic pain are the main symptoms of endometriosis . its etiology is not clear . endometriosis may have various causes , including vitamin d deficiency , but its effect is controversial.material/methodsin this ...
[ [ "it is generally accepted that microleakage between the filling materials and root canal \n walls might adversely affect the outcome of root canal treatment .", "therefore , it is critical the complete \n sealing of the root canal system after cleaning and shaping in order to avoid the \n bacterial penetr...
objectivethe aim of this study was to compare the correspondence between gap formation and apical microleakage in root canals filled with epoxy resin - based ( ah plus ) combined or not with resinous primer or with a dimethacrylate - based root canal sealer ( epiphany ) . material and methodsthirty - nine lower s...
[ [ "neonatal diabetes mellitus ( ndm ) presenting within the first 6 months of life includes permanent neonatal diabetes mellitus ( pndm ) , which require lifelong therapy , and transient neonatal diabetes mellitus ( tndm ) where the condition shows remission during infancy but relapses in adolescence .", "a...
permanent neonatal diabetes mellitus refers to diabetes that occurs before the age of 6 months and persists through life . it is a rare disorder affecting one in 0.2 - 0.5 million live births . mutations in the gene kcnj11 , encoding the subunit kir6.2 , and abcc8 , encoding sur1 of the atp - sensitive potassium ( katp...
[ [ "radiocontrast - induced nephropathy ( rin ) can lead to acute renal failure ( arf ) , which may require dialysis therapy .", "arf increases treatment cost due to sepsis , hemorrhage , respiratory failure , and a long hospitalization.[13 ] rin is an important cause of hospital - acquired arf and is respon...
radiocontrast administration is an important cause of acute renal failure . in this study , compared the plasma creatinine levels with spot urine il-18 levels following radiocontrast administration . twenty patients ( 11 males , 9 females ) underwent radiocontrast diagnostic and therapeutic - enhanced examinations . th...
[ [ "according to the u.s . national institutes of health , up to 80% of human bacterial infections involve biofilm - associated microorganisms 1 . among these , implant - related infections", "do still have a tremendous impact in orthopaedics and trauma 2 , with high social and economic costs 3 , 4 , posing ...
living in biofilms is probably the most common condition for bacteria and fungi and biofilm - related infections account for the majority of bacterial infectious diseases worldwide.among others biofilm - related infections , those associated with implanted biomaterials have an enormous and still largely underestimated ...
[ [ "in 2011 , who declared combat drug resistance : no action today , no cure tomorrow . . in recent years", "presently , antimicrobial resistance ( amr ) poses a major threat to patient 's treatment as it leads to increased morbidity and mortality , increased hospital stay , and severe economic loss to th...
background and objective . antimicrobial resistance is now a major challenge to clinicians for treating patients . hence , this short term study was undertaken to detect the incidence of multidrug - resistant ( mdr ) , extensively drug - resistant ( xdr ) , and pandrug - resistant ( pdr ) bacterial isolates in a tertia...
[ [ "ureterocele is a congenital urinary abnormality characterized by the presence of an intrabladder hernia or cystic ballooning of the lower end of a ureter lying between the mucosa and muscle of the bladder .", "the abnormality leads to urinary retention and recurrent urinary tract infection ( uti ) , whic...
ureterocele is a common ureteric anomaly detected in pediatric population . ureterocele diagnosis and evaluation need a variety of radiological methods . we report a case of 5-year - old female child sent for 99mtc - diethylene triamine pentaacetic acid scan for evaluation of glomerular filtration rate and excretory fu...
[ [ "health - related quality of life ( hrqol ) is a multidimensional concept that defines a person 's health based on specific aspects , such as physical , emotional , and social functioning and general welfare ( 1 ) .", "the assessment of hrqol consists of an evaluation of the degree to which these aspects ...
objectives : the aim of this study was to investigate the impact of asymptomatic vertebral fractures on the quality of life in older women as part of the sao paulo ageing & health study.methods:this study was a cross - sectional study with a random sample of 180 women 65 years of age or older with or without vertebral ...
[ [ "the majority of women with menorrhagia , postcoital bleeding , intermenstrual bleeding , or postmenopausal bleeding ultimately undergo diagnostic hysteroscopy with endometrial sampling as part of their assessment , particularly if symptoms persist or pelvic imaging suggests a uterine abnormality .", "dil...
aims . our aim is to compare the adequacy and diagnostic yield of samples obtained by the endometrial explora sampler i - mx120 with endometrial specimens obtained by conventional dilatation and curettage ( d&c ) . methods . a total of 1270 endometrial samples were received in the histopathology laboratories at the kin...
[ [ "the geological and ( palaeo-)biological evolution of lowland amazonia during neogene and quaternary times remains fascinating since the early days of natural sciences ( for summaries of research history see e.g. , loczy , 1963 and wesselingh , 2008 ) .", "many , but partly highly controversial models hav...
in miocene times a vast wetland existed in western amazonia . whereas the general development of this amazing ecosystem is well established , many questions remain open on sedimentary environments , stratigraphical correlations as well as its palaeogeographical configuration . several outcrops located in a barely studi...
[ [ "with increasing availability , widened indications , and technical refinements of computed tomography ( ct ) and magnetic resonance imaging ( mri ) , the number of incidentally discovered adrenal lesions , such as adrenal incidentalomas and incidental adrenal enlargement , is increasing . in a recent study b...
aim . to investigate incidental adrenal enlargement clinical characteristics and functional status and analyze functional lesion risk factors . materials and methods . this retrospective study included 578 patients with adrenal imaging features showing enlargement . incidental adrenal enlargement cases ( 78 ) were cons...
[ [ "pursuing the goal of improved health literacy requires more alliances between health and education sectors to improve literacy levels in the population .", "it is important for health educators to know about knowledge transfer to meet their needs in transferring their knowledge to public", ". knowled...
objectivethe purpose of this study is to propose an innovative method of knowledge transfer that aims to improve health literacy about pediatric infectious diseases prevention in families . children have an appreciable role in this scheme.methodsthis study is a before and after trial that has been conducted in hamedan ...
[ [ "septic arthritis of the shoulder is uncommon in adults . it is a surgical emergency as joint destruction occurs rapidly and can lead to significant morbidity and mortality ." ], [ "a 43 years old male came to our outpatient department with complaints of pain and stiffness of his left shoulder . on ex...
introduction : septic arthritis of the shoulder is uncommon in adults . it is a surgical emergency as joint destruction occurs rapidly and can lead to significant morbidity and mortality . accurate diagnosis can be particularly challenging in patients with underlying liver disease . mri is a useful adjunct in early det...
[ [ "split - liver transplantation ( slt ) is an attractive alternative procedure to expand the donor pool in patients waiting for liver transplantation .", "the standard split - liver procedure for a child and an adult ( adult / pediatric split liver ttransplantation , a / p slt ) , by splitting segment ...
biliary complications continue to be a major cause of morbidity after split - liver transplantation ( slt ) . in this report we describe an uncommon late biliary complication . one year after slt the patient showed an intrahepatic bile dicy dilatation with severe cholangitis episodes . the segmentary bile duct of hepat...
[ [ "ribonucleotide reductase ( rr ) inhibitors have been studied as radiation sensitizers for over 30 years in both the lab and the clinic .", "the first of these , hydroxyurea , has been studied in both cervical and head and neck cancers , among others .", "although initially promising , many of the cl...
ribonucleotide reductase ( rr ) , the rate limiting enzyme in the synthesis and repair of dna , has been studied as a target for inhibition in the treatment of cancer for many years . while some researchers have focused on rr inhibitors as chemotherapeutic agents , particularly in hematologic malignancies , some of the...
[ [ "the study of long bones and the cells of the bone marrow is central to a myriad of research disciplines , including , but not limited to , bone biology , cancer biology , immunology , hematology , and biomechanics .", "the bone is a highly dynamic organ that together with the cartilage forms the skeleton...
investigation of the bone and the bone marrow is critical in many research fields including basic bone biology , immunology , hematology , cancer metastasis , biomechanics , and stem cell biology . despite the importance of the bone in healthy and pathologic states , however , it is a largely under - researched organ d...
[ [ "tuberculosis ( tb ) is a major health issue in developing countries with over two billion people being infected with tuberculosis bacilli world wide ( 1 ) . although tb was recently regarded primarily as a disease of the developing countries it is now also on the increase in developed countries such as the u...
tuberculosis ( tb ) is a major health issue in both developing and developed countries such as the uk . healthy individuals who contract the infection have only 5 - 10% chance of converting to the active disease over their lifetime . we present the clinical history of a 76 year old female who attended the emergency dep...
[ [ "the value of the ketogenic diet ( kd ) has been recognized in the treatment of epilepsy , although the exact mechanisms by which it exerts its effect remain an enigma .", "they seem to be different from those of regular antiepileptic medications ( aeds ) , and discovering what they are may lead to its us...
although the ketogenic diet ( kd ) has been widely accepted as a legitimate and successful therapy for epilepsy and other neurological disorders , its mechanism of action remains an enigma . the use of the kd causes major metabolic changes . the most significant of them seems to be the situation of chronic ketosis , bu...
[ [ "the endotracheal tube ( ett ) should be placed at the optimal level to avoid inadvertent complication .", "if the ett is too deep , it increases the risk of unintended single lung ventilation .", "on the other hand , if the ett is too shallow , it may cause vocal cord injury by the ett balloon or acc...
abstractendotracheal tube ( ett ) should be placed at the optimal level to avoid single lung ventilation or accidental extubation . this study was performed to estimate the mid - tracheal level by using surface anatomical landmarks in adult patients.neck computed tomography images of 329 adult patients between the ages...
[ [ "embryos generated through assisted reproductive technologies ( art ) are deemed surplus when , for some reason , they are not used for reproductive purposes ( svendsen and koch 2008 ; haimes and taylor 2011 ) ; instead , they are then disposed of or , where this is allowed by a country s art regulation , may...
this paper is based on linked qualitative studies of the donation of human embryos to stem cell research carried out in the united kingdom , switzerland , and china . all three studies used semi - structured interview protocols to allow an in - depth examination of donors and non - donors rationales for their donation ...
[ [ "thyroid cancer is the most common endocrine neoplasia which accounts for about 1% of human cancers .", "mtc originates from calcitonin - producing cells ( c - cells ) of the thyroid gland and accounts for 35% of thyroid cancers .", "mtc is relatively slow - growing tumor but , if metastasized or rela...
medullary thyroid carcinoma ( mtc ) , which originates from thyroid parafollicular c cells , accounts for 3 to 5% of thyroid malignancies . mtc occurs either sporadically or in an inherited autosomal dominant manner . hereditary mtc occurs as a familial mtc or as a part of multiple endocrine neoplasia ( men ) type 2a a...
[ [ "neurosurgery is characterized by the delicate balance between surgical success and potential for devastating side effects . thanks to multiple technological improvements", ", the morbidity of neurosurgical interventions has substantially decreased over the last decades , allowing for the resection of pre...
current neuronavigation systems can not adapt to changing intraoperative conditions over time . to overcome this limitation , we present an experimental end - to - end system capable of updating 3d preoperative images in the presence of brain shift and successive resections . the heart of our system is a nonrigid regis...
[ [ "the contribution to human health of the specific fatty acid ( fa ) composition of the diet has received considerable attention in the literature .", "fatty acids are key nutrients that affect early growth and development as well as the prevention of chronic disease in later life.1 among the fas , omega-3...
omega-3 polyunsaturated fatty acids ( n-3 pufas ) , particularly eicosapentanoic acid ( epa ) and docosahexanoic acid ( dha ) , has been acknowledged as essential very long - chain fatty acids contributing to either achieving optimal health or protection against diseases , and even longevity . recent high impact studie...
[ [ "sexual development in males is a multistep process , implying a delicate network of molecular events that directs the bipotential gonad to differentiate into testis ( sex determination ) and consequent differentiation of internal and external genitalia in the presence of testicular hormones ( sex differentia...
background and objectives:46 xy disorders of sexual development ( dsd ) cover a wide spectrum of phenotypes ranging from unambiguous female genitalia to ambiguous male genitalia with hypospadias or dysgenetic gonads . management of these patients depends on the cause of dsd , degree of feminization , age at presentatio...
[ [ "urinary tract infection ( uti ) is a frequent cause of morbidity both in the community and in the hospital setting .", "the causative pathogen can vary greatly geographically , and so it is prudent to identify those with resistant strains and have current data on the appropriate empirical therapy within ...
abstracturinary tract infections are one of the most common infectious diseases diagnosed in the community and in the hospital setting . their treatment is complicated by drug - resistant pathogens and the colonization by microbes of indwelling urinary catheters . this study assessed the occurrence and antimicrobial su...
[ [ "acquired angioedema ( aae ) , an acquired deficiency of c1esterase inhibitor , is a medically treatable condition which can cause severe abdominal pain mimicking an acute surgical abdomen .", "this disorder is strongly associated with chronic lymphocytic leukemia ( cll ) and other indolent lymphoplasmacy...
introductionacquired angioedema ( aae ) , an acquired deficiency of c1esterase inhibitor , is a medically treatable condition which can cause severe abdominal pain mimicking an acute surgical abdomen . this disorder is strongly associated with chronic lymphocytic leukemia ( cll ) and other indolent lymphoplasmacytic di...
[ [ "" ], [ "" ], [ "distal clavicle fractures associated with partial and complete coracoclavicular ligament disruption are potentially unstable , and non - operative treatment of these fractures is associated with a high non - union rate.[13 ] partial ligament disruptions ( conoid or trapezoid )...
purpose : distal clavicle fracture associated with complete coracoclavicular ligament disruption represents an unstable injury , and osteosynthesis is recommended . this study was performed ( 1 ) to retrospectively analyse the clinico - radiological outcomes of two internal fixation techniques , and ( 2 ) to identify a...
[ [ "a 68-year - old woman visited the clinic with the chief complaints of pain , swelling , and a warm sensation in her left thigh for over 2 days prior to her visit .", "the patient also complained about a warm sensation during the nighttime but body temperature was normal when measured in the clinic .", ...
a 68-year - old woman who suffered from polycythemia vera presented at our clinic with the chief complaints of pain , swelling , and a warm sensation in her left thigh . she had undergone a left bipolar hemiarthroplasty following a hip fracture 24 days prior to this presentation . her erythrocyte sedimentation rate and...
[ [ "brachial plexus surgery using the da vinci surgical robot is a new procedure . to evaluate the advantages and the restrictions of the technique , a cadaveric study of supraclavicular and axillary approaches was conducted .", "we found that the axillary approach was useful and advantageous for lower roots...
brachial plexus surgery using the da vinci surgical robot is a new procedure . although the supraclavicular approach is a well known described and used procedure for robotic surgery , axillary approach was unknown for brachial plexus surgery . a cadaveric study was planned to evaluate the robotic axillary approach for ...
[ [ "older people have particular spiritual needs that are distinct from those of others , particularly in times of ill health and death and dying .", "it has been reported that spirituality has a positive effect on health outcomes and welfare of the elderly .", "nowadays , aging phenomenon and relevant p...
background : spirituality is recognized as a personally important matter to the elderly , and there are evidences of its impact on their health . the aim of this study was to explore the concept of spirituality from the perspectives of iranian healthy elderly individuals.materials and methods : a conventional qualitati...
[ [ "according to the national regulations regarding diagnostic criteria of brain death ( bd ) , instrumental confirmatory tests should be used in certain clinical situations , such as intoxications , infratentorial processes , extensive facial damage , children younger than 2 years of age , or any case in which...
introductionstasis filling , defined as delayed , weak , and persistent opacification of proximal segments of the cerebral arteries , is frequently found in brain dead patients . this phenomenon causes a major problem in the development of reliable computed tomographic angiography ( cta ) protocol in the diagnosis of b...
[ [ "gastric cancer is the second most frequent neoplasm of the alimentary tract after the large intestine .", "5,103 people in poland were affected by it in 2008 . the case - to - death ratio of around 1 indicates unfavourable prognosis as to recovery from this disease [ 1 , 2 ] .", "this poor result is ...
the typical symptoms of advanced cancer of the stomach are well known in clinical practice . the presented case concerns a patient with symptoms of left - sided renal colic , caused by a malignant tumour involving the ureter , which was diagnosed with a ct scan . the multifocal process , involving the stomach , two par...
[ [ "eosinophilic gastritis is an extremely rare disease that is characterized by eosinophilic infiltration of the various layers of the gastrointestinal tract in the absence of any definite causes of eosinophilia .", "patients with eosinophilic gastritis have diverse symptoms , including abdominal pain , eme...
eosinophilic gastroenteritis is very rare disorder that is characterized by eosinophilic infiltration of the gastrointestinal tract in the absence of any definite causes of eosinophilia . it is associated with various clinical gastrointestinal manifestations , and depends on the involved layer and site . we report a ca...
[ [ "the skin is the largest organ of the body and protects the organism against external physical , chemical , and biological insults such as wounding , uvb radiation , and microorganisms .", "this major barrier resides in the upper layers of the epidermis ( for review see segre , 2006 ) . the epidermis is t...
caspase-14 is a unique member of the evolutionarily conserved family of cysteinyl aspartate specific proteinases , which are mainly involved in inflammation and apoptosis . however , recent evidence also implicates these proteases in proliferation and differentiation . although most caspases are ubiquitously expressed ...
[ [ "gossypiboma ( retained surgical sponge ) describes a mass of cotton or sponge that is left behind in the body cavity during a surgical operation .", "these foreign bodies can often mimic tumors or abscesses when detected clinically or with radiation .", "in fact , surgical sponges without opaque mark...
gossypiboma is a term used to describe a foreign mass within the body that is composed of a cotton matrix . gossypiboma can cause infection or abscess formation from an early stage , or it can remain clinically silent for many years . gossypiboma can be diagnosed using several methods including abdominal x - ray films ...
[ [ "to demonstrate the usefulness of enhanced depth imaging optical coherence tomography ( edi - oct ) in investigating choroidal lesions inaccessible to ultrasound sonography ." ], [ "in a 60-year - old woman with an asymptomatic choroidal nevus , normal oct was used to observe the macula and edi - oct ...
purposeto demonstrate the usefulness of enhanced depth imaging optical coherence tomography ( edi - oct ) in investigating choroidal lesions inaccessible to ultrasound sonography.methodsin a 60-year - old woman with an asymptomatic choroidal nevus , normal oct was used to observe the macula and edi - oct to image the c...
[ [ "kelch - like ech - associated protein 1 ( keap1)-nuclear factor e2-related factor 2 ( nrf2 ) is a major cellular pathway that protect normal cells against oxidative and xenobiotic damage.1 nrf2 is an essential transcription factor for antioxidant and detoxification genes and is crucial for the chemopreventiv...
nuclear factor e2-related factor 2 ( nrf2 ) is a transcription factor that upregulates expression of a battery of genes to combat oxidative and electrophilic stress . modification of kelch - like ech - associated protein 1 ( keap1 ) by reactive oxygen species stabilizes nrf2 by escaping from degradation . nrf2 then bin...
[ [ "a 3-year - old male , known to have isolated speech delay , presented to the emergency department with severe body aches and inability to walk .", "few days prior to his presentation , the child started to have flu - like symptoms in the form of rhinorrhea and low - grade fever .", "this was followed...
rhabdomyolysis is an acute life - threatening condition that can occur in childhood secondary to many causes . the authors report the case of a 3-year - old male child who presented with acute rhabdomyolysis . the peak plasma creatine kinase level was extremely high . the 2 main causes of rhabdomyolysis in childhood ar...
[ [ "the study was approved by the institutional ethics committee , and informed consent was obtained from all patients in accordance with the tenets of the declaration of helsinki .", "the donors were selected based on these inclusion criteria : myopic spherical refractive error ranging from 0.5 d to 10.00 d...
purpose : to describe the technique of cryopreservation of corneal lenticules extracted after small incision refractive lenticule extraction ( relex smile ) and initial results of femtosecond laser intrastromal lenticular implantation for hyperopia.methods:lenticules were collected from patients undergoing relex smile ...
[ [ "sepsis is the major cause of death in the intensive care unit . despite improvement of antibiotics treatment and supportive techniques , the mortality of septic shock increases to approximately 60% .", ", it not only helps doctors to make an early diagnosis of sepsis , but also predicts outcomes .", ...
objective . to investigate the prognostic significance of serum soluble triggering receptor expressed on myeloid cells-1 ( strem-1 ) , procalcitonin ( pct ) , n - terminal probrain natriuretic peptide ( nt - pro - bnp ) , c - reactive protein ( crp ) , cytokines , and clinical severity scores in patients with sepsis . ...
[ [ "nine male competitive cyclists participated in this study . their mean sd age , height , and body mass were 33.3 7.5 yr , 184 4 cm , and 77.3 7.0 kg , respectively .", "they had a maximal oxygen consumption ( vo2max ) of 4.8 0.2 lmin ( oxycon pro ; viasys healthcare , germany ) with a peak power out...
abstractpurposethis study aimed to determine the effects of heat acclimatization on performance and pacing during outdoor cycling time trials ( tt , 43.4 km ) in the heat.methodsnine cyclists performed three tt in hot ambient conditions ( tth , approximately 37c ) on the first ( tth-1 ) , sixth ( tth-2 ) , and 14th ( t...
[ [ "worksites in glass and metal works , foundries , rolling mills , in the vicinity of hardening furnaces , rotary kilns in the cement industry , high - temperature laboratory furnaces , as well as firefighting , are associated , in addition to common mechanical hazards ( e.g. , due to splashes of molten metals...
the paper analyses the selected optical parameters of protective optic filters used for protection of the eyes against hazardous radiation within the visible ( vis ) and near infrared ( nir ) spectrum range . the indexes characterizing transmission and reflection of optic radiation incident on the filter are compared ....
[ [ "this retrospective observational study was conducted using electronic medical records from the south central veterans affairs health care network ( visn 16 ) , one of the largest of the 23 visns in the veterans health administration ( vha ) .", "the vha is a national integrated health care system providi...
objectivethis study compared the clinical and economic benefits associated with dual - goal achievement , glycated hemoglobin ( hba1c ) < 7% ( 53 mmol / mol ) and ldl cholesterol ( ldl - c ) < 100 mg / dl , with achievement of only the ldl - c goal or only the hba1c goal in veterans with type 2 diabetes mellitus ( t2dm...
[ [ "endotracheal intubation is one of the most important skills for anesthesiologists in securing the airway during general anesthesia and resuscitation .", "failure to secure the airway can cause anesthesia - related life - threatening morbidity and mortality .", "however , the difficult laryngoscopy an...
backgroundthe aim of this study was to determine if ultrasound ( us ) measurements of anterior neck soft tissue thickness at hyoid bone ( dshb ) , thyrohyoid membrane ( dsem ) , and anterior commissure ( dsac ) levels can be used to predict difficult laryngoscopy.material/methodswe included 203 patients age 2065 years ...
[ [ "" ], [ "w celu oceny wpywu perikardiotomii tylnej na wystpowanie wysiku osierdziowego , tamponady oraz migotania przedsionkw przeprowadzono prospektywne badanie kliniczne z randomizacj ." ], [ "badana grupa skadaa si z 96 pacjentw ( 77 mczyzn i 19 kobiet ) w wieku rednio 58,1 9,8 roku .", ...
introductionpericardial effusion and atrial fibrillation occur commonly after coronary artery surgery.aim of the studya prospective randomized clinical trial was conducted to evaluate the effects of posterior pericardiotomy on the occurrence of pericardial effusion , tamponade , and atrial fibrillation.material and met...
[ [ "cancer places a huge burden on society and has been identified as the leading cause of death in both more and less economically developed countries .", "projections based on the globocan 2012 estimates predict a substantive increase to 19.3 million new cancer cases per year by 2025 , due to growth and ag...
cisplatin is an effective drug used in the treatment of many cancers , yet its ototoxic potential places cancer patients , exposed to this drug , at risk of hearing loss , thus negatively impacting further on a patient 's quality of life . it is paramount for health care practitioners managing such patients to be aware...
[ [ "the synthetic modification \n of proteins enables the construction \n of biomolecular hybrids that can be used to study protein function , deliver potent therapeutics to cellular targets , and build new materials .", "the synthesis of these constructs requires a suite of chemoselective \n bioconjugation ...
the synthetic modification of proteins plays an important role in chemical biology and biomaterials science . these fields provide a constant need for chemical tools that can introduce new functionality in specific locations on protein surfaces . in this work , an oxidative strategy is demonstrated for the ef...
[ [ "\n alcohol withdrawal syndrome ( aws ) is characterized by varied symptoms that range from mild to severe intensity depending on several factors including the quantity , frequency and duration of alcohol intake , and the number of prior withdrawal episodes , as well as individual differences in the vulnerabi...
objective . to identify the underlying factor structure of alcohol withdrawal syndrome , as measured with ciwa - ar . methods . exploratory factor analysis was conducted on the items of ciwa - ar . on 201 alcohol - dependent male patients seeking treatment for alcohol withdrawal at 36 hours of abstinence . results . a ...
[ [ "twenty - two workers were followed up from 15th april to 30th april 2008 during working hours , from approximately 6 am to 3 pm , for a total of 160 working hours .", "this included only workers who had worked more than 50% of each day 's working period and had worked for at least 10 days of the follow -...
backgroundheat illness is a major cause of preventable morbidity worldwide . workers exposed to intense heat can become unable to activate compensation mechanisms , putting their health at risk . heat stress also has a direct impact on production by causing poor task performance and it increases the possibility of work...
[ [ "choroid plexus papilloma ( cpp ) is a rare benign tumor accounting for 0.5% of all intracranial tumors that is more common in childhood , consisting of 1.5 to 6.4% of pediatric intracranial tumors.1 \n", "2 the majority of cpps occur during the first 2 years of life , with 12.5 to 20% ( 10 to 12% ) repor...
choroid plexus papilloma is a rare benign tumor accounting for 0.5% of all intracranial tumors . the majority of choroid plexus papillomas occur during the first 2 years of life in the ventricular system . moreover , dense calcification of the tumor is uncommon . we report an adult case of densely calcified , atypical ...
[ [ "multipath signals occur in numerous microwave and rf applications when an unwanted portion of the original transmission propagates along any alternate path and ultimately couples to the receiver distorting the amplitude and phase of the desired signal [ 14 ] .", "if the amplitude of the multipath signal ...
microwave imaging techniques are prone to signal corruption from unwanted multipath signals . near - field systems are especially vulnerable because signals can scatter and reflect from structural objects within or on the boundary of the imaging zone . these issues are further exacerbated when surface waves are generat...
[ [ "jaw cysts are usually painless , but they can increase in size as they absorb neighboring structures .", "enucleation generally induces bone regeneration within a cystic lesion less than 3 cm in diameter and eliminates the lesion ; however , it is difficult to postoperatively predict lesion recurrence an...
objectivesthe purpose of this study is to evaluate the treatment efficacy of enucleation after decompression.materials and methodsa total of 17 patients with cystic lesion of the jaw were treated with decompression followed by enucleation . pre- and postdecompression panoramic radiographs were analyzed.resultsthe mean ...
[ [ "for the first time , the presented data suggest that a variant in the retn gene plays a significant role in acne pathogenesis .", "we also demonstrate an excess transmission of mutant allele g at retn-420 from 130 trio families using tdt analysis .", "therefore , we suggest that inherited variation i...
resistin ( retn ) , recently found to be relevant to inflammation and inflammatory disorders . we , therefore , aimed to investigate the potential role of retn gene polymorphism in pathogenesis of acne vulgaris with familial history . we investigated the retn-420c / g polymorphism in 180 patients with acne vulgaris and...
[ [ "many studies over the past 15 years have focused on discovering solvents that help promote efficient cc bond formation under benign reaction conditions .", "new solvents in dielsalder(2 ) and barbier reactions have been sought to help streamline the one - pot transformations further , reducing synthetic ...
indium - promoted coupling reactions between propargyl aldehydes ( 1 ) and -chloropropargylphenyl sulfide are reported . although water has been shown to accelerate indium metal promoted reactions , the reverse pattern was observed in this series . use of n - methylformamide ( nmf ) , which has not previously been a so...
[ [ "sepsis is the systemic inflammation caused by infection with bacteria , viruses , fungi , parasites , or toxic products , and has become one of the leading causes of mortality in children . in developed countries ,", "the mortality rate of pediatric sepsis is about 210% and is as high as 50% in developin...
backgroundpediatric sepsis has high morbidity in children , may lead to acute kidney injury ( aki ) , and further aggravate the disease . baicalin is a kind of flavonoid in scutellaria baicalensis georgi and has been reported to protect against several diseases , but its roles in septic aki remain unclear . this study ...
[ [ " the main cause of treatment failure and death in cancer patients is metastasis the formation of secondary tumors in organs distant from the original neoplastic cell tissue .", "adjuvant therapy of proven efficacy is not currently available for cancer patients ; therefore , the search for new targets...
the receptor for advanced glycation end - products ( rages ) is associated with the malignancy of cancer . a recent study has suggested that glyceraldehyde - derived ages ( glycer - ages ) enhanced the malignancy of melanoma cells , but glucose - derived ages did not . however , the effects of glycer - ages on other ca...
[ [ "osseointegrated implants are a practical alternative to traditional prosthodontics ; however , designing an implant - supported prosthesis with function and esthetics is a challenge .", "malaligned implants often complicate the clinical laboratory procedures employed for fabrication of superstructures . ...
aim : demand from implant patients for quality and efficient treatment is increasing . fortunately dental implant treatment is evolving with patients expectations.materials and methods : the study comprised of 45 patients for whom 89 implants were placed at different sites . efficacy of the stents is evaluated in deter...
[ [ "type 1 diabetes ( t1d ) is characterized by autoimmune destruction of pancreatic -cells , primarily mediated by t lymphocytes , resulting in insulin deficiency and lifelong exogenous insulin dependence ( 1 ) .", "latent autoimmune diabetes in adults ( lada ) is a subtype of autoimmune diabetes , but the ...
objectiveb lymphocytes play an important role in the immunopathogenesis of autoimmune diabetes . we hypothesized that the altered b - cell subset phenotype is associated with autoimmune diabetes.research design and methodspatients with type 1 diabetes ( t1d ) ( n = 81 ) , latent autoimmune diabetes in adults ( lada ) (...
[ [ "human papillomavirus ( hpv ) , a virus from the papillomavirus family , is capable of infecting humans . about 200 different strains of hpv identified , based on dna homology , have been found to be etiologically linked to cervical , vaginal , vulvar , penile , anal , oral , and plantar infectious lesions an...
human papillomavirus ( hpv ) infection is the leading cause of cancer mortality among women worldwide . the molecular understanding of hpv proteins has significant connotation for understanding their intrusion in the host and designing novel protein vaccines and anti - viral agents , etc . genomic , proteomic , structu...
[ [ "according to numerous estimations , 15% to 29% of patients with cataract have 1.5 diopters ( d ) of refractive astigmatism.1,2 cataract surgeons usually prefer to treat cataract and correct refractive ( spherical and astigmatic ) disorders at the time of the surgery .", "corneal incision ( astigmatic ker...
purpose : to present clinical results of toric intraocular lens ( iol ) implantation for preexisting astigmatism correction and determine the time of any postoperative rotation.patients and methods : twenty - nine eyes of 19 patients underwent uncomplicated phacoemulsification and were implanted with an acrysof toric ...
[ [ "song is a complex , learned motor skill that involves the precise coordination of vocal and respiratory musculature in order to produce highly stereotyped renditions of a memorized song model .", "two pathways contributed to this behavior are identified in the songbird forebrain : the motor pathway that ...
the song of zebra finch is stable in life after it was learned successfully . vocal plasticity is thought to be a motor exploration that can support continuous learning and optimization of performance . the activity of ra , an important pre - motor nucleus in songbird 's brain , influences the song directly . this vari...
[ [ "first described by veterinarians , pythiosis is a serious life- and limb - threatening infection endemic to thailand , but rarely seen in the western hemisphere .", "known to infect immunocompetent horses , dogs , and other large animals,2 , 3 \n pythium infection was first reported in humans in 1989 in ...
introductionpythiosis is a serious life- and limb - threatening infection endemic to thailand , but rarely seen in the western hemisphere . here , we present a unique case of vascular pythiosis initially managed with limb - sparing vascular bypass grafts complicated by a pseudoaneurysm in our repair.presentation of cas...
[ [ "" ], [ "tissue culture methods and irradiation procedure have been described in . the three dimensional tissue culture model", "( 3d epioral ) and media were purchased from mattek corporation ( ashland , ma ) .", "the 3d epioral tissue is a co - culture organotypic model and consisted of huma...
we evaluated a three - dimensional ( 3d ) human oral cell culture that consisted of two types of cells , oral keratinocytes and fibroblasts as a model of oral mucositis which is a debilitating adverse effect of chemotherapy and radiation treatment . the 3d cell culture model was irradiated with 12 or 2 gy , and total ...
[ [ "adolescents in sub - saharan africa face high exposure to human immunodeficiency virus ( hiv ) infection . despite all efforts to prevent the disease , prevalence estimates in sub - saharan unaids ( i.e. , the joint united nations programme on hiv and aids ) priority countries range from 1.3 to 15.6 % among...
self - report of sexual behavior among adolescents is notoriously inconsistent , yet such measures are commonly used as outcomes for human immunodeficiency virus ( hiv ) prevention intervention trials . there has been a growing interest in the use of hiv and other sexually transmitted disease biomarkers as more valid m...
[ [ "stroke is rare in children , however , a common cause of neurological disease , and it is a major cause of death ranks in the top ten in pediatric period11,15 ) . documented incidence has been reported as 2.5 - 8/100000 children / year12,13 ) .", "medical treatment includes maintaining cerebral perfusion...
objectivelife - threatening hemispheric stroke is associated with a high mortality and morbidity . decompressive hemicraniectomy has been regarded as an effective treatment option for refractory intracranial hypertension . here , we reported the clinical course of 5 children with decompressive craniectomy and duroplast...
[ [ "this was a double - blind , randomized , crossover trial in accordance with the declaration of helsinki and good clinical practice .", "the primary objective was to assess albuminuria during different treatments compared with that with placebo ; secondary objectives were to assess effect on 24-h blood pr...
objectivewe investigated whether the antiproteinuric effect of the direct renin inhibitor aliskiren is comparable to that of irbesartan and the effect of the combination.research design and methodsthis was a double - blind , randomized , crossover trial . after a 1-month washout period , 26 patients with type 2 diabete...
[ [ "nanobiomaterials are characterized by constituent \n particles and/or surface features less than 100 nm \n in at least one dimension \n . \n starting with photolithography and dry etching in the \n 1980 's to high - resolution electron beam lithography and other technologies \n in the 1990 's", ", nanot...
cell - surface interactions play a crucial role for biomaterial application in orthopaedics . it is evident that not only the chemical composition of solid substances influence cellular adherence , migration , proliferation and differentiation but also the surface topography of a biomaterial . the progressive applica...
[ [ "six a17 bac and one fosmid library were used to create mt3.5 ( table s1 ) .", "most were processed by sanger paired - end sequencing of 3 - 6 kb shotgun libraries .", "sequences were downloaded in february / march 2009 with scaffolding performed by aligning all bac and fosmid ends against contigs and...
legumes ( fabaceae or leguminosae ) are unique among cultivated plants for their ability to carry out endosymbiotic nitrogen fixation with rhizobial bacteria , a process that takes place in a specialized structure known as the nodule . legumes belong to one of the two main groups of eurosids , the fabidae , which inclu...
[ [ "surgical treatment of avascular necrosis ( avn ) of head of femur include core decompression , osteotomies , nonvascularized bone grafting , free vascularized fibular grafts , hip resurfacing , bipolar hip arthroplasty ( bha ) and total hip arthroplasty ( tha).123 tha is indicated in the young individual in ...
background : bipolar hip arthroplasty ( bha ) is one of the options for treatment of avascular necrosis ( avn ) of the femoral head . acetabular erosion and groin pain are the most allowing for gross motion between the common complications . we propose that these complications are secondary to improper acetabular prepa...
[ [ "the success of valproic acid ( vpa , 2-propylpentanoic acid ) , a short branched chain fatty acid , for the therapy of absence seizures , partial seizures , tonic - clonic seizures , bipolar disorder , schizoaffective disorder , social phobias , neuropathic pain and for the prophylaxis and treatment of migra...
valproic acid ( vpa ) has successfully been used in the therapy of a number of conditions including absence seizures , partial seizures , tonic - clonic seizures , bipolar disorder , schizoaffective disorder , social phobias , neuropathic pain and migraine headaches . there is a high rise in number of cases of toxicity...
[ [ "intramammary infection ( mastitis ) is the most common reason for the use of antimicrobials in dairy cows .", "antimicrobials have been used to treat mastitis for more than fifty years , but consensus about the most efficient , safe , and economical treatment is still lacking .", "the concept of evid...
treatment of mastitis should be based on bacteriological diagnosis and take national and international guidelines on prudent use of antimicrobials into account . in acute mastitis , where bacteriological diagnosis is not available , treatment should be initiated based on herd data and personal experience . rapid bacter...
[ [ "approximately 40 million people are infected with the human immunodeficiency virus ( hiv ) worldwide ( unaids 2006 ) .", "infections by this lentivirus from the family retroviridae are characterized by a long asymptomatic period after host immune defenses control the initial infection . during this subse...
abstractmany pathogens of humans are blood borne , including hiv , malaria , hepatitis b and c , west nile virus , dengue , and other viral hemorrhagic fevers . although several of these pathogens are transmitted by blood - feeding arthropods , hiv is not . a number of properties of hiv and its life cycle have been ide...
[ [ "in the normal kidney , immunohistochemical expression of contractile protein alpha - smooth muscle actin ( asma ) is limited to the vascular smooth muscle cells . in pathological conditions , the expression of asma", "the first experimental publication on this subject , by johnson et al , involved a seri...
summarybackgroundin a healthy kidney , contractile protein alpha - smooth muscle actin ( asma ) is immunohistochemically strongly expressed only in the blood vessels , while in pathological conditions it can be visualized in glomerular mesangial cells and interstitial myofibroblasts . the aim of this study was to explo...
[ [ "chondroblastoma accounts for < 1% of all primary bone tumors . usually occurring in young adolescents ,", "however , unusual sites of presentation such as patella , talocalcaneal , and temporomandibular joint has been reported .", "since last decade , fine needle aspiration cytology ( fnac ) has evol...
chondroblastoma is a rare , giant cell - rich , benign neoplasm of bone . since the past few decades fine needle aspiration cytology ( fnac ) has gained momentum in preoperative diagnosis of bone lesions . at cytology , other giant cell - rich tumors and tumorlike lesions such as aneurysmal bone cyst ( abc ) , giant ce...
[ [ "suicide is a grave public health issue with a global mortality rate of 16 per 100,000 individuals.1 suicide is one of the top three leading causes of death , particularly among individuals aged 1544 years , which is a productive age group.1 suicide is a complex event that is influenced by biological , cultur...
backgroundsuicide is a grave public health issue that is responsible for a high mortality rate among individuals aged 1544 years . attitudes toward suicide among medical staff members have been associated with appropriate therapeutic responses to suicidal individuals . the aim of this study was to examine the effects o...
[ [ "copd is characterized by persistent airway obstruction , usually of a progressive nature and associated with an enhanced chronic inflammatory response in airways to noxious particles or gases.1 copd is associated with increased mortality and reduced life expectancy.2 of the 3.8 million mortalities caused by ...
backgroundlow adherence to global initiative for chronic obstructive lung disease ( gold ) guideline recommendations has been reported worldwide . there has been no study on the adherence to gold guidelines for copd treatment in turkey.objectivesto investigate the rates of adherence to gold 2010 guidelines for copd tre...
[ [ "amphotericin b ( amb ) , an amphoteric polyene macrolide , has been considered one of the main options of antifungal therapy for serious and life - threatening mycotic infections for over 50 years despite the introduction of newer antifungal medications such as the azoles ( e.g. , voriconazole ) and echinoca...
backgroundnephrotoxicity is the most clinically significant adverse reaction of amphotericin b. different aspects of amphotericin b ( amb ) nephrotoxicity have not been studied well in our population.objectivesthe purpose of this study was to assess the frequency , time onset , and possible associated factors of amb ne...
[ [ "o - glycans have been found to play an important role in protein stability and tertiary structure , stabilize protein conformation , modulate the activity of enzymes ( e.g. by reversible attachment of o - linked glcnac to cytoplasmic and nuclear proteins ) and signaling molecules , are essential for a number...
the glycosylation abilities of snails deserve attention , because snail species serve as intermediate hosts in the developmental cycles of some human and cattle parasites . in analogy to many other host - pathogen relations , the glycosylation of snail proteins may likewise contribute to these host - parasite interacti...