Datasets:

xpertsystems
/

hc-res-004-sample

patient_id string	region string	ethnicity string	sex string	age_at_diagnosis float64	pediatric_flag int64	socioeconomic_status string	hh_crowding_index_persons_per_room float64	ventilation_quality string	tb_disease_type string	tb_site string	pulmonary_flag int64	tb_lineage string	prior_tb_episode_flag int64	smear_result_baseline string	culture_result_baseline string	genexpert_mtb_result string	genexpert_rif_resistance string	lpa_first_line_result string	lpa_second_line_result string	whole_genome_sequencing_done int64	diagnostic_delay_days float64	healthcare_system_delay_days float64	igra_result string	tst_mm float64	chest_xray_pattern string	cavitation_flag int64	diagnostic_platform string	hiv_status string	cd4_count_at_tb_dx_cells_ul float64	art_status_at_tb_dx string	art_regimen string	art_start_timing_weeks float64	cotrimoxazole_prophylaxis_flag int64	tb_iris_severity string	virologic_suppression_flag int64	hiv_viral_load_copies_ml float64	opportunistic_infection_flag int64	isoniazid_resistance string	rifampicin_resistance string	ethambutol_resistance string	pyrazinamide_resistance string	fluoroquinolone_resistance string	bedaquiline_resistance string	linezolid_resistance string	clofazimine_resistance string	delamanid_resistance string	pretomanid_resistance string	cycloserine_resistance string	drug_resistance_category string	resistance_acquisition_type string	mutation_catalog_tier string	mic_isoniazid_ug_ml float64	mic_rifampicin_ug_ml float64	weight_kg_at_dx float64	treatment_regimen string	planned_duration_months int64	dot_flag int64	dot_type string	fixed_dose_combination_flag int64	dose_adjustment_flag int64	treatment_initiation_delay_days float64	drug_dose_isoniazid_mg float64	drug_dose_rifampicin_mg float64	drug_dose_bedaquiline_mg int64	drug_dose_linezolid_mg int64	adherence_overall_pct float64	adherence_intensive_phase_pct float64	adherence_continuation_phase_pct float64	doses_missed_total int64	dose_interruption_flag int64	interruption_duration_days int64	interruption_reason string	ltfu_flag int64	ltfu_time_months float64	pill_count_ratio float64	adherence_counseling_sessions int64	patient_support_program_flag int64	treatment_support_index float64	adverse_event_severity_score float64	culture_negative_month2_flag int64	culture_negative_month5_flag int64	smear_negative_month2_flag int64	sputum_conversion_month float64	smear_series_m0_m5 string	relapse_flag int64	relapse_time_months_post_tx float64	reinfection_vs_relapse_wgs string	drug_resistance_acquisition_during_tx int64	log_time_to_kill_hrs float64	treatment_outcome string	actual_duration_months float64	bmi_at_diagnosis float64	moderate_acute_malnutrition_flag int64	hospitalization_flag int64	hospitalization_days_total int64	icu_flag int64	adverse_events_grade3_4_flag int64	hepatotoxicity_flag int64	peripheral_neuropathy_flag int64	qtc_prolongation_flag int64	visual_impairment_flag int64	myelosuppression_flag int64	hearing_loss_flag int64	treatment_failure_time_months float64	mortality_time_months_from_start float64	mortality_cause string	total_treatment_cost_usd float64	catastrophic_cost_flag int64	household_contacts_count int64	contacts_screened_count int64	secondary_attack_rate_pct float64	contacts_ltbi_positive_count int64	contacts_active_tb_identified int64	ltbi_treatment_started_pct float64	ltbi_treatment_completed_pct float64	transmission_cluster_wgs_flag int64	snp_distance_to_cluster float64	nat2_acetylator_status string	rifampicin_cmax_ug_ml float64	rifampicin_auc024_ug_hr_ml float64	isoniazid_cmax_ug_ml float64	bedaquiline_cmax_ng_ml float64	bedaquiline_trough_ng_ml float64	qtcf_baseline_ms float64	qtcf_on_treatment_ms float64	linezolid_trough_ug_ml float64	cyp3a4_inducer_interaction_flag int64	drug_exposure_quartile int64	tbdrug_hepatotoxicity_score float64	facility_level string	tb_program_type string	tb_notification_channel string	treatment_center_distance_km float64	monthly_transport_cost_usd float64	food_basket_support_flag int64	social_protection_flag int64
HC_RES_004_0000001	Upper_Middle	Sub_Saharan_African	Female	52.1	0	Low	1.2	Moderate	MDR-TB	Pulmonary	1	L4_Euro_American	0	Negative	Positive	Detected_L	Not_Detected	INH_R	Susceptible	1	80	30	Negative	0.6	Other	0	Culture_DST	Negative	null	null	null	null	0	null	1	null	0	Resistant	Resistant	Susceptible	Susceptible	Susceptible	Susceptible	Resistant	Susceptible	Susceptible	Susceptible	Susceptible	MDR-TB	Primary	WHO_Tier_1	0.827	2.961	59.4	BDQ_LZD_Cfz_PZA	20	0	null	0	0	16	297	594	400	600	63.4	71.7	56.1	0	0	0	null	1	0.8	0.82	6	0	79.2	2.5	0	1	1	5	1\|1\|1\|1\|0\|0	0	0	null	0	74.8	LTFU	20.6	17.2	1	1	16	0	0	0	0	0	0	0	0	0	0	null	4,693	1	4	3	15.8	0	0	53.6	62.9	0	null	Rapid	28	67.9	4.47	25	1.5	397	416	2.378	0	2	2.5	Primary_HC	NGO_Supported	Electronic_DHIS2	16.8	24	0	0
HC_RES_004_0000002	Upper_Middle	Sub_Saharan_African	Male	25.8	0	Middle	2.3	Poor	Pre-XDR-TB	Pleural	0	L2_East_Asian	0	Positive_2+	Negative	Detected_H	Not_Detected	Susceptible	Susceptible	1	101	12	Positive	10.4	Infiltrate_Patchy	0	Culture_DST	Negative	null	null	null	null	0	null	1	null	0	Resistant	Resistant	Susceptible	Susceptible	Resistant	Susceptible	Resistant	Susceptible	Susceptible	Susceptible	Resistant	Pre-XDR-TB	Acquired	WHO_Tier_2	2.697	1.482	76.4	BPaL	20	0	null	0	0	1	382	764	400	0	83.6	92.2	80.3	1	1	19	Stigma	0	0	0.458	7	1	84	2.5	0	1	0	5.2	3\|3\|3\|2\|1\|0	0	0	null	0	200.8	Treatment_Completed	18.9	17.1	1	1	16	0	1	0	0	0	0	0	0	0	0	null	12,383	0	5	1	21.3	0	0	80	72.4	1	0	Rapid	27.23	33.9	4.76	25	2.938	425	455	0	0	4	0.8	Primary_HC	NTP_DOT	Electronic_DHIS2	1.5	37.1	1	0
HC_RES_004_0000003	High_Burden	South_Asian	Female	41.9	0	High	4.6	Good	LTBI	Lymph_Node	0	L4_Euro_American	0	Negative	Positive	Detected_M	Not_Detected	Susceptible	Susceptible	0	56	13	Positive	5.2	Infiltrate_Patchy	0	GeneXpert_Only	Negative	null	null	null	null	0	null	1	null	0	Susceptible	Susceptible	Susceptible	Susceptible	Susceptible	Susceptible	Susceptible	Susceptible	Susceptible	Susceptible	Susceptible	Pan_Susceptible	Primary	Novel	1.22	2.136	58.8	1HP_Rifapentine_INH	3	0	null	0	0	14	294	588	0	0	88.2	97	85.1	3	0	0	null	0	0	0.919	6	0	51.6	10	1	1	1	0	2\|0\|0\|0\|0\|0	0	0	null	0	34.8	Cured	7	20.8	0	0	0	0	0	0	0	0	0	0	0	0	0	null	194	1	8	7	33.7	2	0	88	41.6	1	1	Slow	28	47.9	15	0	0	421	431	0	0	1	0.9	Tertiary_Reference	NTP_DOT	Paper	26.1	10.8	1	0
HC_RES_004_0000004	Low_Burden	South_Asian	Female	27.8	0	High	2.8	Moderate	MDR-TB	Lymph_Node	0	L1_Indo_Oceanic	0	Positive_2+	Positive	Detected_L	Not_Detected	Susceptible	SLID_R	0	20	13	Negative	12.6	Infiltrate_Patchy	0	GeneXpert_LPA	Negative	null	null	null	null	0	null	1	null	0	Resistant	Resistant	Susceptible	Susceptible	Susceptible	Susceptible	Resistant	Susceptible	Susceptible	Susceptible	Susceptible	MDR-TB	Primary	Novel	1.475	0.436	81.4	STREAM_Short_Course	18	0	null	1	0	5	407	814	0	0	78.5	84	71.6	1	0	0	null	0	0	0.367	3	0	56.9	3.8	1	1	0	3.1	2\|1\|0\|0\|0\|0	0	0	null	0	81.3	LTFU	20.7	21	0	0	0	0	0	0	1	1	0	1	0	0	0	null	10,339	0	2	1	34.1	0	0	53.9	54.9	0	null	Slow	28	40.6	15	0	0	403	419	0	0	4	1.8	District_Hospital	NTP_DOT	Electronic_DHIS2	16.5	18.6	1	0
HC_RES_004_0000005	Upper_Middle	Sub_Saharan_African	Male	12.7	1	High	3.6	Moderate	MDR-TB	Pulmonary	1	L1_Indo_Oceanic	0	Positive_1+	Positive	Detected_L	Not_Detected	Susceptible	Susceptible	0	99	27	Negative	0	Infiltrate_Patchy	0	GeneXpert_Only	Negative	null	null	null	null	0	null	1	null	0	Resistant	Resistant	Susceptible	Susceptible	Susceptible	Susceptible	Susceptible	Resistant	Susceptible	Susceptible	Susceptible	MDR-TB	Primary	WHO_Tier_1	0.756	1.956	54.5	Individualized_MDR	18	1	Video_DOT	0	0	53	272	545	0	0	34.4	40.8	27.2	2	1	19	Economic	0	0	0.692	9	0	52.3	6.9	0	1	1	1	0\|0\|0\|0\|0\|0	0	0	null	1	62.3	Failed	18.3	18	1	1	31	0	1	0	0	0	0	0	0	8.9	0	null	9,449	0	5	2	13.7	0	0	80.3	89.4	0	null	Rapid	23.65	19.1	1.51	0	0	428	429	0	0	3	0.9	District_Hospital	NTP_DOT	Electronic_DHIS2	4.3	17.3	1	0
HC_RES_004_0000006	Upper_Middle	Eastern_European	Male	47.4	0	High	2.4	Good	Pre-XDR-TB	Pulmonary	1	L2_East_Asian	0	Positive_3+	Positive	Not_Detected	Not_Detected	RIF_R	FLQ_R	0	13	3	Positive	9.2	Infiltrate_Patchy	0	GeneXpert_Only	Negative	null	null	null	null	0	null	1	null	0	Resistant	Resistant	Susceptible	Susceptible	Resistant	Susceptible	Susceptible	Susceptible	Susceptible	Susceptible	Susceptible	Pre-XDR-TB	Primary	Novel	2.193	1.364	30.6	BPaL	20	1	Video_DOT	0	0	2	153	450	400	0	35.4	44.8	33	0	1	3	Distance	1	1.3	0.97	9	0	27.8	0	0	0	1	5.9	4\|4\|3\|2\|1\|0	0	0	null	0	150.4	Died	19.8	21	0	1	19	0	0	1	0	0	0	0	0	0	3.5	TB	16,588	1	7	4	36.7	1	0	60.3	43.3	0	null	Intermediate	23.12	24	5.08	25	2.457	399	432	0	0	2	0.2	Tertiary_Reference	NTP_DOT	Paper	2	4.7	1	0
HC_RES_004_0000007	Low_Burden	South_Asian	Male	10.1	1	High	3.2	Moderate	MDR-TB	Pulmonary	1	L4_Euro_American	0	Positive_3+	Negative	Detected_L	Not_Detected	INH_R	SLID_R	0	5	79	Positive	22.8	Other	0	GeneXpert_Only	Negative	null	null	null	null	0	null	1	null	0	Resistant	Resistant	Susceptible	Susceptible	Resistant	Susceptible	Susceptible	Susceptible	Susceptible	Susceptible	Susceptible	MDR-TB	Acquired	WHO_Tier_1	4.952	0.681	53.1	BDQ_LZD_Cfz_Cs	20	0	null	0	1	4	266	531	400	600	77.4	84.6	71.4	0	0	0	null	0	0	0.822	2	1	100	2.1	0	1	1	1.4	1\|1\|0\|0\|0\|0	0	0	null	0	95.7	LTFU	20.7	25.1	0	0	0	0	0	0	0	1	0	0	0	0	0	null	6,445	1	5	4	11.3	0	0	47.3	66.9	1	7	Rapid	28	81.5	4.3	25	3.215	426	412	1.068	0	1	1.5	Primary_HC	NTP_DOT	Electronic_DHIS2	40.1	52.5	0	1
HC_RES_004_0000008	Low_Burden	Sub_Saharan_African	Female	37.5	0	High	2.8	Poor	DS-TB	Pulmonary	1	L2_East_Asian	0	Positive_2+	Negative	Detected_H	Not_Detected	RIF_R	Susceptible	0	41	66	Positive	15.1	Miliary	0	GeneXpert_Only	Negative	null	null	null	null	0	null	1	null	0	Susceptible	Resistant	Susceptible	Susceptible	Susceptible	Susceptible	Susceptible	Susceptible	Susceptible	Susceptible	Susceptible	Mono_Resistant	Primary	WHO_Tier_2	0.532	2.265	53	2HRZE_4HR	6	1	SAT	1	0	3	265	530	0	0	81.7	88.9	74.4	3	0	0	null	1	1.8	0.771	7	1	42.8	1.4	0	1	0	1.1	4\|3\|0\|0\|0\|0	0	0	null	0	146	Treatment_Completed	8.9	16.2	1	0	0	0	0	0	0	0	0	0	0	0	0	null	1,375	1	4	2	20.2	0	0	69.2	71.1	1	0	Intermediate	18.84	91.6	6.92	0	0	411	419	0	0	2	4	District_Hospital	NTP_DOT	Paper	0.8	10.7	0	0
HC_RES_004_0000009	Upper_Middle	Other	Female	37	0	Low	3.9	Good	DS-TB	Pulmonary	1	L4_Euro_American	1	Positive_1+	Positive	Detected_L	Not_Detected	Susceptible	Susceptible	1	68	42	Positive	12.8	Cavitary	0	GeneXpert_Only	Negative	null	null	null	null	0	null	1	null	0	Susceptible	Susceptible	Susceptible	Susceptible	Susceptible	Susceptible	Susceptible	Susceptible	Susceptible	Susceptible	Susceptible	Pan_Susceptible	Acquired	WHO_Tier_2	0.539	0.361	56	2HRZE_4H3R3	6	0	null	1	0	1	280	560	0	0	80.7	88.8	75	0	0	0	null	1	0.7	0.564	8	1	73.8	3.2	1	0	0	2.6	0\|0\|0\|0\|0\|0	0	0	null	0	240	Cured	6	18.2	1	0	0	0	0	0	0	0	0	0	0	0	0	null	1,346	1	5	3	15.9	0	0	69.6	54.7	1	1	Rapid	28	51.9	5.98	0	0	401	405	0	0	4	0.1	Primary_HC	NTP_DOT	Paper	1	32.2	0	0
HC_RES_004_0000010	Low_Burden	South_Asian	Male	48.9	0	High	4	Good	DS-TB	Disseminated	0	L4_Euro_American	0	Negative	Positive	Detected_H	Not_Detected	INH_R	FLQ_SLID_R	1	13	49	Positive	22.4	Infiltrate_Patchy	0	GeneXpert_LPA	Negative	null	null	null	null	0	null	1	null	0	Susceptible	Susceptible	Susceptible	Susceptible	Susceptible	Susceptible	Susceptible	Susceptible	Susceptible	Susceptible	Susceptible	Pan_Susceptible	Primary	WHO_Tier_1	1.536	0.434	57.4	2HRZE_4HR	6	1	Video_DOT	1	1	26	287	574	0	0	73.3	80.7	70.9	2	1	15	Economic	1	5.3	0.538	6	1	84.5	3.1	0	1	1	2.2	2\|1\|0\|1\|0\|0	0	0	null	0	25.8	Treatment_Completed	3	22.1	0	0	0	0	0	0	0	0	0	0	0	0	0	null	930	1	5	4	23.8	1	0	46.4	69.1	0	null	Rapid	28	55.7	2.75	0	0	386	410	0	0	1	1.5	Primary_HC	NGO_Supported	Electronic_DHIS2	32.5	3.9	1	0
HC_RES_004_0000011	High_Burden	Sub_Saharan_African	Female	31.8	0	Low	2.6	Poor	XDR-TB	Pulmonary	1	L2_East_Asian	0	Negative	Positive	Detected_L	Not_Detected	Susceptible	Susceptible	0	111	7	Negative	6.8	Infiltrate_Patchy	0	Culture_DST	Negative	null	null	null	null	0	null	1	null	0	Resistant	Resistant	Susceptible	Susceptible	Resistant	Susceptible	Susceptible	Susceptible	Susceptible	Susceptible	Susceptible	XDR-TB	Acquired	WHO_Tier_2	1.161	2.499	54.1	BPaL	24	1	Community_HW	0	0	5	271	541	400	0	68	77.3	61.7	4	1	4	Economic	0	0	0.674	10	0	46.8	2.1	1	0	1	13.1	0\|0\|0\|0\|0\|0	0	0	null	0	176.4	Failed	18.2	20.8	0	0	0	0	0	0	0	1	0	0	0	1	0	null	32,336	0	7	6	11.3	1	0	66.2	81.7	1	1	Slow	28	65.9	7.06	25	1.368	424	456	0	0	2	0.4	District_Hospital	Private_Sector	Electronic_DHIS2	23.9	17	0	0
HC_RES_004_0000012	Low_Burden	South_Asian	Male	43	0	Middle	3.9	Poor	MDR-TB	Pulmonary	1	L2_East_Asian	1	Positive_2+	Positive	Detected_H	Detected	Susceptible	Susceptible	0	56	50	Indeterminate	0	Other	0	Culture_DST	Negative	null	null	null	null	0	null	1	null	0	Resistant	Resistant	Susceptible	Susceptible	Susceptible	Susceptible	Susceptible	Susceptible	Susceptible	Susceptible	Susceptible	MDR-TB	Acquired	WHO_Tier_2	0.729	6.454	48.4	Individualized_MDR	18	1	Facility_DOT	0	0	4	242	484	0	0	92.4	100	87.2	0	1	20	Side_effects	0	0	0.881	4	0	68.2	1.2	1	1	0	4.3	2\|1\|1\|1\|0\|1	1	2.1	Relapse	0	59	Cured	17.9	13.8	1	0	0	0	0	0	0	0	0	0	0	0	0	null	9,131	0	2	1	38.2	0	0	67.2	20.8	1	0	Rapid	25.05	65.4	7	0	0	420	434	0	0	4	0.2	Primary_HC	NGO_Supported	Electronic_DHIS2	10	14.9	0	0
HC_RES_004_0000013	Upper_Middle	Sub_Saharan_African	Female	34.9	0	Middle	4	Moderate	DS-TB	Pulmonary	1	L2_East_Asian	0	Positive_1+	Positive	Detected_H	Not_Detected	Susceptible	SLID_R	0	60	24	Positive	15.9	Other	0	Culture_DST	Negative	null	null	null	null	0	null	1	null	0	Susceptible	Susceptible	Resistant	Susceptible	Susceptible	Susceptible	Susceptible	Susceptible	Susceptible	Susceptible	Susceptible	Mono_Resistant	Primary	WHO_Tier_2	0.545	0.107	49.3	2HRZE_4H3R3	6	1	Video_DOT	1	0	23	246	493	0	0	91.3	97.2	88.8	0	0	0	null	0	0	0.82	4	1	93.2	10	1	1	1	3.2	3\|2\|1\|0\|0\|0	0	0	null	0	81.6	Treatment_Completed	5.6	21.7	0	1	17	0	1	0	1	0	1	0	1	0	0	null	824	0	4	3	36.8	1	0	77.4	65	1	3	Rapid	28	105.1	12.77	0	0	386	392	0	0	3	5.2	District_Hospital	NTP_DOT	Electronic_DHIS2	3	4.3	0	0
HC_RES_004_0000014	High_Burden	Latin_American	Male	39.1	0	Low	5.8	Moderate	XDR-TB	Pulmonary	1	L4_Euro_American	0	Scanty	Positive	Detected_M	Not_Detected	Susceptible	Susceptible	0	121	21	Positive	19.1	Cavitary	1	GeneXpert_Only	Negative	null	null	null	null	0	null	1	null	0	Resistant	Resistant	Susceptible	Resistant	Resistant	Susceptible	Resistant	Susceptible	Susceptible	Susceptible	Resistant	XDR-TB	Primary	WHO_Tier_2	0.222	2.533	57.9	BPaLM	24	0	null	0	1	10	290	579	400	0	47.1	53.3	39.9	7	1	11	Economic	0	0	0.413	4	1	100	5.2	0	1	0	5.1	0\|0\|0\|0\|0\|0	1	5.4	Reinfection	0	114	LTFU	19.4	21.8	0	1	49	0	0	0	0	0	0	0	0	0	0	null	34,045	1	2	1	18.1	0	0	85.7	79.1	1	3	Slow	28	60.4	10.26	25	1.521	416	448	0	0	4	4.3	Tertiary_Reference	Private_Sector	Electronic_DHIS2	9.6	29.8	0	0
HC_RES_004_0000015	High_Burden	Eastern_European	Male	53.4	0	Middle	4.9	Moderate	DS-TB	Abdominal	0	L4_Euro_American	0	Positive_1+	Positive	Detected_H	Not_Detected	Susceptible	SLID_R	0	33	48	Positive	10	Other	0	GeneXpert_LPA	Negative	null	null	null	null	0	null	1	null	0	Susceptible	Susceptible	Susceptible	Susceptible	Susceptible	Susceptible	Susceptible	Susceptible	Susceptible	Susceptible	Susceptible	Pan_Susceptible	Primary	WHO_Tier_1	0.277	0.545	50.3	2HRZE_4H3R3	6	1	SAT	0	1	21	252	503	0	0	88.7	93	85.6	1	1	13	Economic	0	0	0.454	6	0	65.6	0.9	1	1	1	1.2	2\|2\|0\|1\|0\|0	0	0	null	0	108	Cured	6	17.6	1	0	0	0	1	1	0	0	0	0	0	0	0	null	756	1	3	2	25.2	1	0	38.7	44.7	1	0	Rapid	28	35.5	6.35	0	0	387	395	0	0	2	0.9	District_Hospital	NTP_DOT	Electronic_DHIS2	23.3	21.4	0	0
HC_RES_004_0000016	High_Burden	Sub_Saharan_African	Male	80.9	0	Middle	3.3	Good	XDR-TB	Pulmonary	1	L4_Euro_American	0	Negative	Positive	Detected_VH	Not_Detected	INH_RIF_R	SLID_R	0	5	60	Positive	12.3	Cavitary	1	GeneXpert_Only	Positive	81	On_ART	TDF_3TC_DTG	3.1	1	null	1	25	1	Resistant	Resistant	Resistant	Resistant	Resistant	Resistant	Susceptible	Susceptible	Susceptible	Susceptible	Resistant	XDR-TB	Acquired	Novel	5.945	1.795	37.4	Individualized_XDR	6	0	null	1	0	17	187	450	0	0	47.8	54.6	38.9	1	0	0	null	0	0	0.615	6	1	96.1	0.7	0	1	0	1.5	2\|1\|0\|0\|0\|1	0	0	null	0	55.7	Cured	18.7	20.4	0	1	21	1	0	0	0	1	0	0	1	0	0	null	19,622	1	4	3	22.3	1	1	68.3	50.8	0	null	Rapid	28	37.1	11.78	0	0	422	412	0	0	4	2.7	Tertiary_Reference	NTP_DOT	Electronic_DHIS2	2.3	19.8	1	0
HC_RES_004_0000017	High_Burden	Sub_Saharan_African	Male	35.3	0	Middle	2.9	Poor	DS-TB	Pulmonary	1	L3_East_African_Indian	0	Negative	Positive	Not_Detected	Not_Detected	INH_R	Susceptible	0	146	21	Positive	9.7	Cavitary	0	GeneXpert_LPA	Negative	null	null	null	null	0	null	1	null	0	Susceptible	Susceptible	Susceptible	Susceptible	Susceptible	Susceptible	Susceptible	Susceptible	Susceptible	Susceptible	Susceptible	Pan_Susceptible	Primary	WHO_Tier_1	8.356	0.577	57.5	2HRZE_4HR	6	1	Facility_DOT	0	1	1	288	575	0	0	85.1	92.7	78.2	0	0	0	null	1	0.5	0.885	0	1	61.4	0.6	1	1	0	4.1	0\|0\|0\|0\|0\|0	0	0	null	0	68.5	Cured	7.4	15.7	1	0	0	0	0	0	0	0	0	0	0	0	0	null	1,694	0	2	1	17.2	0	0	86.9	92.3	0	null	Intermediate	28	45	12.31	0	0	422	434	0	0	1	0.3	Tertiary_Reference	Private_Sector	Paper	8.4	18	0	0
HC_RES_004_0000018	High_Burden	Sub_Saharan_African	Male	45.8	0	Middle	5.4	Poor	MDR-TB	Lymph_Node	0	L2_East_Asian	1	Positive_3+	Positive	Detected_L	Indeterminate	INH_R	Susceptible	1	51	38	Positive	13.1	Infiltrate_Patchy	0	GeneXpert_Only	Negative	null	null	null	null	0	null	1	null	0	Resistant	Resistant	Susceptible	Susceptible	Susceptible	Susceptible	Susceptible	Susceptible	Susceptible	Susceptible	Susceptible	MDR-TB	Primary	Novel	14.644	0.672	67.5	BDQ_LZD_Cfz_PZA	18	1	Facility_DOT	0	0	1	337	675	400	300	48.4	56.2	45.8	3	1	16	Stigma	0	0	0.792	8	1	91.2	4.7	1	1	1	3.2	3\|2\|1\|0\|0\|0	0	0	null	0	33.5	Cured	21.1	18.3	1	0	0	0	0	0	1	0	0	0	0	0	0	null	6,420	1	1	0	24.7	0	0	71.9	74.4	0	null	Rapid	23.14	46.3	5.02	25	3.935	438	499	2.397	0	3	4.2	Tertiary_Reference	NTP_DOT	Electronic_DHIS2	19.9	6.5	0	0
HC_RES_004_0000019	High_Burden	South_Asian	Male	19.1	0	Middle	3	Poor	DS-TB	Pulmonary	1	L2_East_Asian	0	Positive_2+	Positive	Not_Detected	Detected	Susceptible	Susceptible	0	55	29	Positive	17.8	Cavitary	0	GeneXpert_LPA	Negative	null	null	null	null	0	null	1	null	0	Susceptible	Susceptible	Susceptible	Susceptible	Susceptible	Susceptible	Susceptible	Susceptible	Susceptible	Susceptible	Susceptible	Pan_Susceptible	Primary	WHO_Tier_1	1.613	0.239	51.4	2HRZE_4HR	6	1	Community_HW	1	0	11	257	514	0	0	85.2	87.5	78.3	3	1	14	Stigma	1	3.6	0.767	5	0	60.7	1.9	1	1	1	1.4	2\|2\|0\|0\|0\|0	0	0	null	0	53.4	Failed	1.8	13.8	1	0	0	0	1	0	0	0	0	0	0	1.7	0	null	2,008	0	5	3	38.6	1	0	88.4	63.6	0	null	Intermediate	16.99	27.6	12.14	0	0	453	450	0	0	3	1.6	District_Hospital	NGO_Supported	Electronic_DHIS2	19.9	33.8	0	0
HC_RES_004_0000020	Low_Burden	Sub_Saharan_African	Female	13.9	1	Middle	5.1	Poor	DS-TB	Pulmonary	1	L2_East_Asian	0	Positive_2+	Positive	Detected_H	Not_Detected	Susceptible	Susceptible	1	50	22	Positive	11	Infiltrate_Patchy	0	GeneXpert_LPA	Negative	null	null	null	null	0	null	1	null	0	Susceptible	Susceptible	Susceptible	Susceptible	Susceptible	Susceptible	Susceptible	Susceptible	Susceptible	Susceptible	Susceptible	Pan_Susceptible	Primary	WHO_Tier_1	3.076	1.681	71.7	2HRZE_4HR	6	1	Community_HW	0	0	18	358	717	0	0	89.1	96.6	82.9	3	1	14	Stigma	0	0	0.826	4	1	66	2	0	1	1	1	3\|0\|0\|0\|0\|0	0	0	null	0	213.1	Cured	5.3	21.2	0	1	26	0	0	0	0	0	0	0	0	0	0	null	1,104	0	6	3	33.5	1	0	24.6	81.2	0	null	Rapid	26.39	75.2	2.02	0	0	420	435	0	0	1	1.7	District_Hospital	NTP_DOT	Paper	4	42.8	0	0
HC_RES_004_0000021	Low_Burden	East_Asian	Female	32	0	Middle	2.8	Good	DS-TB	Pulmonary	1	L4_Euro_American	1	Positive_2+	Positive	Detected_L	Detected	INH_R	FLQ_R	0	62	3	Positive	5.9	Cavitary	0	GeneXpert_Only	Negative	null	null	null	null	0	null	1	null	0	Susceptible	Susceptible	Susceptible	Resistant	Susceptible	Susceptible	Susceptible	Susceptible	Susceptible	Susceptible	Susceptible	Mono_Resistant	Primary	WHO_Tier_2	0.068	2.176	52.9	2HRZE_4HR	6	1	Video_DOT	0	0	17	264	529	0	0	93.9	99.4	89.9	0	1	18	Economic	0	0	0.601	3	0	87	5.1	1	1	1	1.1	0\|0\|0\|0\|0\|1	1	5.9	Relapse	1	39.4	Cured	9.7	18.2	1	0	0	0	0	0	1	0	0	0	0	0	0	null	584	1	5	3	11.5	0	2	49.7	80.3	0	null	Intermediate	28	41.4	13.29	0	0	453	460	0	0	3	2.8	Primary_HC	Private_Sector	Electronic_DHIS2	37.7	21	1	0
HC_RES_004_0000022	Upper_Middle	South_Asian	Male	39	0	Middle	2.2	Poor	DS-TB	Pulmonary	1	M_bovis	0	Negative	Positive	Detected_H	Not_Detected	RIF_R	Susceptible	0	90	8	Negative	4.7	Other	0	GeneXpert_Only	Unknown	null	null	null	null	0	null	1	null	0	Susceptible	Susceptible	Susceptible	Susceptible	Susceptible	Susceptible	Susceptible	Susceptible	Susceptible	Susceptible	Susceptible	Pan_Susceptible	Primary	WHO_Tier_1	1.6	0.271	58.2	2HRZE_4HR	6	1	Community_HW	0	1	23	291	582	0	0	81.1	90.1	74.2	1	1	2	Economic	0	0	0.843	8	0	38	2.3	1	0	1	2.4	3\|3\|2\|0\|0\|0	0	0	null	0	91.3	Cured	6.4	19	0	0	0	0	1	0	0	0	0	1	0	0	0	null	1,069	1	4	2	32.4	1	0	73.5	71.8	0	null	Rapid	23.56	96.8	3.3	0	0	422	417	0	0	2	1	Primary_HC	NTP_DOT	Electronic_DHIS2	8.4	21.1	0	0
HC_RES_004_0000023	High_Burden	Sub_Saharan_African	Male	73	0	Low	2.7	Good	MDR-TB	Pulmonary	1	L4_Euro_American	0	Positive_2+	Positive	Detected_M	Not_Detected	INH_R	FLQ_R	0	73	39	Positive	11.2	Infiltrate_Patchy	0	Culture_DST	Negative	null	null	null	null	0	null	1	null	0	Resistant	Resistant	Resistant	Resistant	Susceptible	Susceptible	Susceptible	Susceptible	Susceptible	Susceptible	Resistant	MDR-TB	Primary	Novel	3.088	1.507	48	STREAM_Short_Course	18	1	Facility_DOT	0	0	18	240	480	0	0	73.4	80.7	69.2	1	0	0	null	1	1.3	0.727	4	0	51.6	0.1	0	0	0	1	3\|0\|0\|0\|1\|0	0	0	null	0	35.1	Failed	15.7	23.9	0	1	19	0	0	0	1	1	0	0	0	1.7	0	null	11,095	1	5	4	38.7	2	0	43.8	71.3	1	0	Intermediate	13.99	52.8	6.7	0	0	434	444	0	0	1	2.5	Tertiary_Reference	NGO_Supported	Paper	15.3	21.5	1	1
HC_RES_004_0000024	High_Burden	South_Asian	Male	54	0	Middle	6.2	Poor	MDR-TB	Pulmonary	1	L1_Indo_Oceanic	0	Positive_2+	Positive	Detected_L	Not_Detected	INH_RIF_R	FLQ_R	0	60	10	Positive	11	Infiltrate_Patchy	1	GeneXpert_LPA	Positive	66	On_ART	Other_ART	4.1	1	null	0	25	0	Resistant	Resistant	Susceptible	Susceptible	Susceptible	Susceptible	Susceptible	Susceptible	Susceptible	Resistant	Susceptible	MDR-TB	Primary	WHO_Tier_1	3.511	0.678	53.7	BDQ_LZD_Cfz_Cs	18	1	Facility_DOT	1	0	2	269	537	400	600	55.9	59	46.2	2	0	0	null	0	0	0.846	6	1	74	6.6	1	1	1	2.2	3\|2\|1\|0\|1\|0	0	0	null	0	104.9	Died	15.2	16.3	1	1	39	0	1	0	1	0	0	1	0	0	2.4	HIV_related	4,625	1	2	1	37.7	0	0	73.6	22.7	0	null	Intermediate	22.65	37	2.11	25	4.395	394	419	8.552	1	3	0.8	Primary_HC	NTP_DOT	Electronic_DHIS2	10.9	27.8	0	0
HC_RES_004_0000025	High_Burden	Sub_Saharan_African	Female	29.3	0	Middle	3.9	Moderate	DS-TB	Pulmonary	1	L5_West_African1	0	Negative	Positive	Detected_L	Not_Detected	INH_RIF_R	SLID_R	0	47	64	Positive	13.1	Cavitary	0	Culture_DST	Positive	69	ART_Naive	TDF_3TC_DTG	0	1	null	1	25,000	0	Susceptible	Susceptible	Susceptible	Susceptible	Susceptible	Susceptible	Susceptible	Susceptible	Susceptible	Susceptible	Susceptible	Pan_Susceptible	Primary	WHO_Tier_2	0.649	0.349	78.3	2HRZE_4HR	6	1	Facility_DOT	1	0	1	391	783	0	0	87.9	91.1	81.7	3	0	0	null	0	0	0.949	5	0	69.3	0.4	1	1	0	1.2	3\|2\|0\|0\|0\|0	1	1	Relapse	0	50.5	LTFU	7.2	20.3	0	0	0	0	0	0	0	1	0	0	0	0	0	null	996	1	9	7	24.2	2	0	82.1	76.4	1	2	Rapid	28	44.9	3.44	0	0	445	442	0	0	2	3.3	District_Hospital	NTP_DOT	Paper	24.6	10.1	0	1
HC_RES_004_0000026	High_Burden	Eastern_European	Male	66.9	0	Low	3.3	Moderate	DS-TB	Pulmonary	1	L2_East_Asian	0	Positive_2+	Positive	Detected_VH	Not_Detected	INH_R	Susceptible	0	22	28	Positive	9.3	Other	0	Culture_DST	Negative	null	null	null	null	0	null	1	null	0	Susceptible	Susceptible	Resistant	Susceptible	Susceptible	Susceptible	Susceptible	Susceptible	Susceptible	Susceptible	Susceptible	Mono_Resistant	Primary	WHO_Tier_1	0.422	1.204	58.2	2HRZE_4HR	6	1	SAT	1	0	16	291	582	0	0	66.1	75	60.2	2	0	0	null	0	0	0.846	9	0	76.9	4	1	0	1	1.3	2\|1\|0\|0\|0\|0	0	0	null	0	171.6	Failed	5.8	19.1	0	0	0	0	1	0	0	0	0	0	0	1.7	0	null	566	0	4	2	36.7	1	0	61.8	37.2	0	null	Intermediate	14.4	75	2.37	0	0	441	444	0	0	2	0.1	Tertiary_Reference	NTP_DOT	Electronic_DHIS2	5	4.1	1	0
HC_RES_004_0000027	High_Burden	South_Asian	Male	50.8	0	Low	4.4	Poor	DS-TB	Pleural	0	L1_Indo_Oceanic	0	Negative	Negative	Detected_M	Detected	RIF_R	SLID_R	1	34	27	Positive	8.9	Cavitary	0	Culture_DST	Negative	null	null	null	null	0	null	1	null	0	Susceptible	Susceptible	Susceptible	Susceptible	Susceptible	Susceptible	Susceptible	Susceptible	Susceptible	Susceptible	Susceptible	Pan_Susceptible	Primary	WHO_Tier_1	1.938	3.959	67.4	Other_DS	6	1	Facility_DOT	1	0	1	337	674	0	0	89.8	92	84.3	2	1	6	Feeling_better	0	0	0.788	6	0	89.5	0.3	1	1	1	1.8	3\|2\|0\|0\|0\|1	0	0	null	0	85.3	LTFU	6	18.5	0	0	0	0	0	0	0	0	0	0	0	0	0	null	1,488	0	3	2	26.9	1	0	61	57.8	0	null	Intermediate	18.45	59.2	6.52	0	0	402	399	0	0	3	7	Tertiary_Reference	NTP_DOT	Paper	1.7	12.5	1	0
HC_RES_004_0000028	Low_Burden	South_Asian	Male	22.1	0	High	3.1	Poor	MDR-TB	Pulmonary	1	L3_East_African_Indian	1	Positive_3+	Positive	Detected_M	Not_Detected	Susceptible	Susceptible	1	5	11	Positive	17.8	Cavitary	1	GeneXpert_LPA	Negative	null	null	null	null	0	null	1	null	0	Resistant	Resistant	Resistant	Susceptible	Susceptible	Susceptible	Susceptible	Susceptible	Susceptible	Susceptible	Susceptible	MDR-TB	Acquired	WHO_Tier_2	1.419	1.758	48.9	STREAM_Short_Course	9	0	null	0	0	10	245	489	0	0	15.3	21	10.9	0	0	0	null	0	0	0.786	5	0	72.9	1.5	1	1	1	2.3	2\|1\|1\|0\|0\|0	1	4.3	Reinfection	0	173.2	Died	19.4	16.3	1	0	0	0	1	0	0	0	0	0	0	0	19.1	TB	12,453	0	4	3	30.3	1	0	82.4	54.3	0	null	Intermediate	28	31	5.84	0	0	420	438	0	0	3	1.3	Tertiary_Reference	NTP_DOT	Electronic_DHIS2	13.7	10.9	0	0
HC_RES_004_0000029	High_Burden	Latin_American	Male	35.3	0	Low	5.3	Moderate	Pre-XDR-TB	Pulmonary	1	L5_West_African1	0	Positive_1+	Positive	Detected_VH	Not_Detected	INH_R	FLQ_SLID_R	0	43	6	Positive	17	Cavitary	0	GeneXpert_Only	Negative	null	null	null	null	0	null	1	null	0	Resistant	Resistant	Susceptible	Resistant	Resistant	Susceptible	Susceptible	Resistant	Resistant	Susceptible	Susceptible	Pre-XDR-TB	Primary	Novel	3.672	7.373	62.8	BPaL	20	1	Community_HW	0	0	5	314	628	400	0	81.7	87.9	78.1	0	1	10	Feeling_better	1	2.8	0.941	7	1	57.6	2.9	1	1	1	1	0\|0\|0\|0\|0\|0	0	0	null	0	67.7	Cured	23	18.6	0	1	15	0	0	0	0	0	0	0	0	0	0	null	15,835	1	4	2	17.5	0	0	56.1	70.5	0	null	Rapid	28	87.4	4.88	25	2.412	392	411	0	0	3	0.2	District_Hospital	NTP_DOT	Paper	5.9	39.7	1	0
HC_RES_004_0000030	Upper_Middle	Sub_Saharan_African	Male	42.9	0	Low	2.7	Moderate	DS-TB	Pulmonary	1	L3_East_African_Indian	0	Scanty	Positive	Detected_M	Not_Detected	INH_RIF_R	Susceptible	1	19	6	Negative	0.8	Cavitary	1	GeneXpert_Only	Negative	null	null	null	null	0	null	1	null	0	Susceptible	Susceptible	Susceptible	Susceptible	Susceptible	Susceptible	Susceptible	Susceptible	Susceptible	Susceptible	Susceptible	Pan_Susceptible	Acquired	WHO_Tier_1	1.383	2.118	60.3	Other_DS	6	1	Facility_DOT	0	0	12	302	603	0	0	96	100	86.4	2	0	0	null	0	0	0.494	3	1	86.8	0.2	1	1	1	2.3	2\|1\|1\|0\|0\|0	1	6.7	Relapse	0	151.3	Cured	5.2	21.6	0	1	23	0	0	0	0	0	0	0	1	0	0	null	1,136	1	7	3	22.7	1	0	78.5	70.7	0	null	Rapid	28	37.5	5.62	0	0	451	467	0	0	4	0.1	Primary_HC	NTP_DOT	Electronic_DHIS2	19.4	8	1	0
HC_RES_004_0000031	High_Burden	East_Asian	Male	23	0	Middle	4.3	Poor	DS-TB	Pulmonary	1	L2_East_Asian	0	Positive_1+	Positive	Detected_M	Not_Detected	Susceptible	FLQ_R	0	72	4	Positive	13.3	Other	0	GeneXpert_LPA	Negative	null	null	null	null	0	null	1	null	0	Susceptible	Susceptible	Susceptible	Susceptible	Susceptible	Susceptible	Susceptible	Susceptible	Susceptible	Susceptible	Susceptible	Pan_Susceptible	Primary	WHO_Tier_2	0.222	0.243	42.1	2HRZE_4HR	6	1	Video_DOT	1	1	28	210	450	0	0	86.9	95.4	79.4	6	1	2	Economic	0	0	0.776	13	1	92.7	0.4	0	1	0	1.7	0\|0\|0\|0\|0\|0	0	0	null	0	109	Cured	7	21.4	0	0	0	0	0	0	1	0	0	0	0	0	0	null	1,320	0	5	3	18.4	1	1	84.7	69.1	0	null	Slow	24.88	29.2	6.19	0	0	394	401	0	0	4	0.3	Tertiary_Reference	NTP_DOT	Electronic_DHIS2	10.8	9.3	0	0
HC_RES_004_0000032	High_Burden	Sub_Saharan_African	Female	60.7	0	Low	3.6	Good	MDR-TB	Pulmonary	1	L4_Euro_American	0	Positive_3+	Positive	Detected_H	Detected	RIF_R	SLID_R	0	18	36	Positive	12.1	Cavitary	0	GeneXpert_Only	Negative	null	null	null	null	0	null	1	null	0	Resistant	Resistant	Resistant	Resistant	Susceptible	Susceptible	Susceptible	Susceptible	Susceptible	Susceptible	Susceptible	MDR-TB	Acquired	WHO_Tier_1	0.788	5.224	52.7	Individualized_MDR	9	0	null	0	0	0	263	527	0	0	80.5	89.5	77.2	5	1	10	Side_effects	1	4	0.846	6	1	76.2	0.9	0	0	1	3.2	3\|2\|2\|2\|0\|0	0	0	null	0	77.5	Cured	19.7	23.4	0	0	0	0	0	0	0	1	0	0	0	0	0	null	5,130	0	4	3	38.1	1	0	83.8	32.8	0	null	Intermediate	19.83	23.1	15	0	0	424	433	0	0	1	0.2	District_Hospital	NTP_DOT	Paper	9.6	15.3	0	0
HC_RES_004_0000033	Low_Burden	Eastern_European	Male	31	0	Middle	1.3	Poor	DS-TB	Pulmonary	1	L2_East_Asian	0	Positive_2+	Positive	Detected_M	Not_Detected	INH_R	FLQ_R	1	38	14	Negative	0	Cavitary	0	Culture_DST	Negative	null	null	null	null	0	null	1	null	0	Susceptible	Susceptible	Susceptible	Susceptible	Susceptible	Susceptible	Susceptible	Susceptible	Susceptible	Susceptible	Susceptible	Pan_Susceptible	Primary	WHO_Tier_2	0.101	0.428	52.9	2HRZE_4HR	6	1	SAT	1	0	2	265	529	0	0	93.5	100	89.5	0	0	0	null	1	4.6	0.857	7	0	100	0.4	1	0	1	1.9	3\|3\|0\|0\|0\|0	0	0	null	0	55.1	Cured	4.2	16.9	1	1	35	0	0	0	0	0	0	0	0	0	0	null	944	0	3	2	26.4	1	0	58.6	78.9	1	2	Intermediate	17.52	46.8	10.23	0	0	438	441	0	0	4	0.3	District_Hospital	NGO_Supported	Electronic_DHIS2	0.5	14.1	1	1
HC_RES_004_0000034	Upper_Middle	South_Asian	Male	51.6	0	Low	5.9	Poor	DS-TB	Pulmonary	1	L1_Indo_Oceanic	0	Negative	Negative	Detected_H	Not_Detected	RIF_R	Susceptible	0	14	7	Positive	20.2	Other	1	GeneXpert_LPA	Negative	null	null	null	null	0	null	1	null	0	Susceptible	Susceptible	Susceptible	Susceptible	Susceptible	Susceptible	Susceptible	Susceptible	Susceptible	Susceptible	Susceptible	Pan_Susceptible	Primary	Novel	0.42	0.802	60.1	2HRZE_4HR	6	1	Facility_DOT	0	1	4	301	601	0	0	92.7	100	84.8	3	0	0	null	0	0	0.794	5	0	75.1	1.4	1	1	1	1.1	0\|0\|0\|0\|0\|0	0	0	null	0	109.7	Cured	4.9	26.1	0	0	0	0	1	0	0	0	0	0	0	0	0	null	744	1	5	3	17.8	1	0	83.4	57	1	1	Slow	19.84	33	15	0	0	398	410	0	0	3	1.8	Tertiary_Reference	NTP_DOT	Electronic_DHIS2	9.2	11	1	0
HC_RES_004_0000035	Upper_Middle	Sub_Saharan_African	Male	25	0	Low	2.3	Poor	DS-TB	Pulmonary	1	L4_Euro_American	0	Negative	Negative	Detected_M	Indeterminate	Susceptible	FLQ_SLID_R	0	15	33	Positive	14.8	Cavitary	0	GeneXpert_Only	Negative	null	null	null	null	0	null	1	null	0	Susceptible	Susceptible	Susceptible	Susceptible	Susceptible	Susceptible	Susceptible	Susceptible	Susceptible	Susceptible	Susceptible	Pan_Susceptible	Primary	WHO_Tier_2	0.1	0.377	62.3	2HRZE_4HR	6	1	Community_HW	1	0	5	312	623	0	0	73.8	80.1	67.4	1	0	0	null	0	0	0.727	9	1	73.3	5.9	1	1	1	1	0\|0\|0\|0\|0\|0	0	0	null	0	109.4	Cured	6.5	19	0	0	0	0	0	0	0	0	0	1	0	0	0	null	1,181	1	3	2	17	0	0	78.8	57.1	0	null	Rapid	15.72	75.9	1.61	0	0	460	466	0	0	4	0.7	Primary_HC	NTP_DOT	Electronic_DHIS2	24.7	6.3	0	0
HC_RES_004_0000036	Upper_Middle	Sub_Saharan_African	Male	42.7	0	High	1.2	Good	DS-TB	Pulmonary	1	L2_East_Asian	1	Positive_2+	Positive	Not_Detected	Not_Detected	Susceptible	Susceptible	0	102	19	Positive	16	Cavitary	0	GeneXpert_LPA	Negative	null	null	null	null	0	null	1	null	0	Susceptible	Susceptible	Susceptible	Susceptible	Susceptible	Susceptible	Susceptible	Susceptible	Susceptible	Susceptible	Susceptible	Pan_Susceptible	Primary	WHO_Tier_2	0.748	0.054	75.6	2HRZE_4HR	6	1	Facility_DOT	0	1	10	378	756	0	0	86.5	93.8	79	0	0	0	null	0	0	0.96	9	1	88.7	2.7	1	1	1	1.2	2\|2\|0\|0\|0\|0	0	0	null	0	78.2	Cured	6.4	14.4	1	0	0	0	0	0	0	0	0	0	0	0	0	null	1,235	0	3	2	33.3	1	0	49.9	64.2	0	null	Rapid	14.94	29.5	2.29	0	0	412	422	0	0	3	0.6	Tertiary_Reference	NGO_Supported	Paper	7.3	15.3	0	0
HC_RES_004_0000037	Upper_Middle	South_Asian	Male	26.4	0	Low	3.7	Moderate	DS-TB	Pleural	0	L2_East_Asian	0	Negative	Positive	Detected_VH	Not_Detected	RIF_R	SLID_R	0	22	45	Positive	21.5	Cavitary	0	GeneXpert_LPA	Negative	null	null	null	null	0	null	1	null	0	Susceptible	Susceptible	Susceptible	Susceptible	Susceptible	Susceptible	Susceptible	Susceptible	Susceptible	Susceptible	Susceptible	Pan_Susceptible	Primary	WHO_Tier_1	0.442	0.227	71.6	2HRZE_4HR	6	1	Facility_DOT	1	0	4	358	716	0	0	95.8	100	92.6	0	0	0	null	0	0	0.903	4	0	58.3	0.3	1	1	1	4.1	3\|2\|1\|0\|0\|0	0	0	null	1	32.2	Treatment_Completed	6.5	14.5	1	1	31	0	1	0	0	1	0	0	0	0	0	null	1,220	1	5	2	20.8	0	0	45.4	82.6	0	null	Slow	22.72	67.5	3.91	0	0	448	459	0	0	1	0	Primary_HC	Private_Sector	Electronic_DHIS2	17.9	13.4	0	0
HC_RES_004_0000038	High_Burden	Eastern_European	Male	22.9	0	Middle	3.2	Good	DS-TB	Pulmonary	1	L1_Indo_Oceanic	1	Positive_3+	Positive	Detected_M	Not_Detected	RIF_R	FLQ_R	0	8	49	Positive	12.5	Other	0	GeneXpert_LPA	Negative	null	null	null	null	0	null	1	null	0	Susceptible	Susceptible	Susceptible	Susceptible	Susceptible	Susceptible	Susceptible	Susceptible	Susceptible	Susceptible	Susceptible	Pan_Susceptible	Primary	WHO_Tier_1	1.678	0.242	46.3	2HRZE_4HR	6	1	Facility_DOT	1	0	3	231	463	0	0	49.6	54.8	44	1	1	12	Side_effects	1	3	0.87	8	0	59.8	2.1	1	0	0	1	0\|0\|0\|0\|0\|0	0	0	null	0	73.9	Cured	2.6	17.7	1	1	16	0	0	0	0	0	0	0	0	0	0	null	967	1	10	8	13.8	1	0	86.3	21.8	0	null	Intermediate	20.2	27.7	15	0	0	410	432	0	0	3	0.8	District_Hospital	NTP_DOT	Electronic_DHIS2	5.1	74.4	1	0
HC_RES_004_0000039	High_Burden	Sub_Saharan_African	Female	22.3	0	Low	4	Good	DS-TB	Pulmonary	1	L1_Indo_Oceanic	0	Negative	Positive	Detected_VH	Detected	INH_RIF_R	Susceptible	0	31	39	Negative	0	Cavitary	0	Culture_DST	Negative	null	null	null	null	0	null	1	null	0	Susceptible	Susceptible	Susceptible	Susceptible	Susceptible	Susceptible	Susceptible	Susceptible	Susceptible	Susceptible	Susceptible	Pan_Susceptible	Primary	WHO_Tier_1	0.057	1.52	54.3	2HRZE_4HR	6	1	SAT	0	0	9	271	543	0	0	90.7	99.2	83.5	3	0	0	null	0	0	0.528	6	0	63.1	0.8	1	1	1	2	4\|4\|0\|0\|0\|0	0	0	null	0	49.9	Cured	6.8	14.2	1	0	0	0	0	0	0	0	0	0	1	0	0	null	462	1	4	1	39.2	0	0	67.5	53.2	0	null	Slow	28	95.2	15	0	0	419	421	0	0	3	0.1	Tertiary_Reference	NTP_DOT	Paper	6.9	13.1	0	0
HC_RES_004_0000040	Low_Burden	South_Asian	Female	15.1	0	Middle	1.9	Poor	DS-TB	Pulmonary	1	L2_East_Asian	0	Positive_1+	Positive	Detected_M	Detected	INH_R	Susceptible	1	13	37	Positive	19.7	Normal	1	GeneXpert_LPA	Negative	null	null	null	null	0	null	1	null	0	Susceptible	Susceptible	Susceptible	Susceptible	Susceptible	Susceptible	Susceptible	Susceptible	Susceptible	Susceptible	Susceptible	Pan_Susceptible	Primary	WHO_Tier_2	0.225	0.447	59.7	2HRZE_4HR	6	1	SAT	0	0	5	298	597	0	0	87.4	91.9	78.5	1	1	3	Economic	1	4.1	0.688	3	1	92.6	0.4	1	0	1	1	0\|0\|0\|0\|0\|0	0	0	null	0	117	Cured	8.6	21.5	0	0	0	0	1	0	0	0	0	0	0	0	0	null	1,662	0	6	5	18.8	1	0	54.8	75.9	1	12	Rapid	18.82	43	4.38	0	0	429	433	0	0	4	0.5	Primary_HC	NGO_Supported	Paper	15.9	13	1	0
HC_RES_004_0000041	Upper_Middle	Eastern_European	Female	27.1	0	Low	5.1	Poor	MDR-TB	Pulmonary	1	L1_Indo_Oceanic	0	Positive_1+	Negative	Detected_H	Not_Detected	RIF_R	Susceptible	1	95	56	Positive	12.1	Cavitary	0	GeneXpert_Only	Unknown	null	null	null	null	0	null	1	null	0	Resistant	Resistant	Susceptible	Susceptible	Susceptible	Susceptible	Susceptible	Susceptible	Susceptible	Susceptible	Susceptible	MDR-TB	Primary	WHO_Tier_1	1.64	0.198	66.7	BDQ_LZD_Cfz_Cs	18	0	null	0	1	11	333	667	400	600	74.6	78.7	66.9	2	0	0	null	0	0	0.831	4	0	93.5	4.3	1	1	0	4.6	0\|0\|0\|0\|0\|0	0	0	null	0	87.7	Died	17.7	20.7	0	0	0	0	1	0	0	0	0	0	0	0	3.4	Adverse_drug_reaction	12,286	1	1	0	15.3	0	0	72.5	32.4	0	null	Intermediate	28	37.6	2.56	25	4.77	413	448	2.26	0	3	0.2	Primary_HC	NGO_Supported	Paper	0.9	8.4	1	1
HC_RES_004_0000042	Low_Burden	Eastern_European	Female	40.6	0	Low	3.8	Poor	DS-TB	Pleural	0	L4_Euro_American	0	Positive_1+	Negative	Detected_M	Not_Detected	Susceptible	Susceptible	0	56	41	Negative	6.3	Cavitary	0	Culture_DST	Negative	null	null	null	null	0	null	1	null	0	Susceptible	Susceptible	Susceptible	Susceptible	Susceptible	Susceptible	Susceptible	Susceptible	Susceptible	Susceptible	Susceptible	Pan_Susceptible	Primary	WHO_Tier_1	0.08	0.29	66.1	2HRZE_4HR	6	0	null	0	0	15	330	661	0	0	68.7	77.2	59.7	0	1	16	Economic	0	0	0.652	1	1	53.1	0.7	0	1	1	2.4	3\|3\|3\|0\|0\|0	0	0	null	0	76.8	Cured	7.7	23	0	0	0	0	0	0	0	0	0	0	1	0	0	null	1,078	0	5	4	25	1	0	51.3	70.6	0	null	Rapid	28	45.2	2.12	0	0	421	434	0	0	2	4	Tertiary_Reference	NTP_DOT	Electronic_DHIS2	3.1	11	1	0
HC_RES_004_0000043	Upper_Middle	Sub_Saharan_African	Male	38.3	0	Middle	3.4	Moderate	MDR-TB	Pulmonary	1	L3_East_African_Indian	0	Scanty	Positive	Detected_H	Not_Detected	INH_R	FLQ_R	1	18	22	Positive	17.8	Normal	1	GeneXpert_Only	Negative	null	null	null	null	0	null	1	null	0	Resistant	Resistant	Resistant	Susceptible	Susceptible	Susceptible	Susceptible	Susceptible	Susceptible	Susceptible	Susceptible	MDR-TB	Primary	WHO_Tier_2	1.776	2.203	52.2	BDQ_LZD_Cfz_Cs	20	1	Facility_DOT	0	1	3	261	522	400	600	54.8	57.9	45.1	8	0	0	null	0	0	0.46	6	1	100	4	1	1	1	1.7	2\|1\|0\|0\|0\|0	0	0	null	1	82.3	Cured	14.2	16	1	0	0	0	0	0	0	0	0	1	0	0	0	null	8,854	1	4	2	30.7	1	1	72.7	52	0	null	Rapid	28	92.1	5.02	25	4.502	445	483	1.255	0	4	3	District_Hospital	NTP_DOT	Electronic_DHIS2	12.3	29.9	0	1

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HC-RES-004 — Tuberculosis Synthetic Dataset (Sample)

XpertSystems.ai · Synthetic Data Factory · Respiratory Vertical

The fourth SKU in the XpertSystems Respiratory vertical: a globally-calibrated synthetic tuberculosis cohort spanning the full resistance spectrum — drug-susceptible (DS-TB), multidrug-resistant (MDR-TB), pre-extensively (Pre-XDR-TB), extensively drug-resistant (XDR-TB), and latent (LTBI). It covers diagnosis & molecular testing (GeneXpert, LPA, WGS, smear/culture), an 11-drug resistance profile with MIC proxies, regimen selection (including BPaL/BPaLM and STREAM short-course), adherence & DOT, sputum-conversion bacteriology, WHO-defined treatment outcomes, HIV co-infection, household contact investigation, population PK/PD (NAT2, QTc), and health-system context.

This repository contains a 500-row, single-seed sample. The full commercial product scales to 20,000+ patients with CSV / Parquet / JSON delivery.

SKU: HC-RES-004
Sample size: 500 patients × 138 columns
License (sample): CC-BY-NC-4.0 — commercial license available for the full product
Contact: pradeep@xpertsystems.ai · https://xpertsystems.ai

Validation

This sample passes XpertSystems Grade A+ validation (overall 10.000 / 10) with deterministic reproduction across all six canonical seeds [42, 7, 123, 2024, 99, 1].

Validation philosophy: structural identities over distribution-fit tests — anchored by the resistance-severity gradient (treatment success falls and mortality rises monotonically from DS-TB through XDR-TB) and drug-resistance cascade integrity (DS-TB background isoniazid susceptibility ≥94%). This engine also passes its own built-in ~16-check benchmark suite (WHO type distribution, type-specific success rates, sputum conversion, LTFU, resistance epidemiology, adherence, HIV).

Calibration anchors

Metric	Sample value	Target range	Source
DS-TB prevalence	59.8%	55–70%	WHO Global TB Report 2023 (~62%)
MDR-TB prevalence	20.6%	15–25%	WHO (~20%)
DS-TB treatment success	87.6%	80–92%	WHO (~85%)
MDR-TB treatment success	49.5%	48–68%	Lancet MDR-TB meta-analysis (~57%)
DS-TB 2-month culture conversion	~74%	68–88%	WHO/STREAM
Loss-to-follow-up rate	17.8%	10–24%	Lancet meta-analysis
Mean overall adherence	74.1%	70–88%	TB program data
HIV-TB co-infection	8.0%	4–18%	WHO 2023
Hospitalization rate	40.0%	25–55%	TB inpatient utilization
INH resistance (whole cohort)	37.2%	25–45%	WHO 2022 (incl. MDR/XDR)
RIF resistance (whole cohort)	37.6%	20–40%	WHO 2022
DS-TB background INH-susceptibility	99.7%	≥0.94	Cascade integrity
Success gradient (DS − XDR)	+0.59	≥0.20	Resistance-severity ordering
Mortality gradient (XDR − DS)	+0.37	≥0.08	Resistance-severity ordering
Column count	138	≥132	Schema completeness (11 modules)

Observed severity gradient across the full spectrum (success / mortality): DS-TB 0.87 / 0.02 → MDR-TB 0.55 / 0.10 → Pre-XDR-TB 0.38 / 0.21 → XDR-TB 0.37 / 0.25.

Schema highlights by module (138 columns)

Demographics. Region (burden-stratified), ethnicity, sex, age, pediatric flag, SES, household crowding, ventilation quality.

Classification & diagnosis. TB type, anatomical site, lineage, prior-TB, smear grade, culture, GeneXpert MTB/RIF, line-probe assays (first/second line), WGS, diagnostic & health-system delays, IGRA/TST, chest X-ray pattern, cavitation, diagnostic platform.

Drug resistance. 11-drug susceptibility (INH, RIF, EMB, PZA, FLQ, BDQ, LZD, CFZ, DLD, PA, CS), WHO resistance category, primary vs acquired, mutation-catalog tier, MIC proxies.

Treatment. Type-specific regimen (incl. BPaL/BPaLM, STREAM short-course), planned duration, DOT type, fixed-dose combination, dose adjustment, weight-based drug doses, initiation delay.

Adherence. Overall / intensive / continuation-phase adherence, doses missed, interruptions (duration & reason), LTFU & timing, pill-count ratio, counseling, support program, adverse-event severity.

Bacteriology. 2-/5-month culture & smear conversion, conversion timing, 6-month smear series, relapse (timing, reinfection-vs-relapse by WGS), acquired resistance during treatment.

Clinical outcome. WHO outcome (Cured/Completed/Failed/LTFU/Died), actual duration, BMI & malnutrition, hospitalization & ICU, grade 3-4 adverse events (hepatotoxicity, neuropathy, QTc, visual, myelosuppression, hearing loss), failure/death timing & cause, treatment cost, catastrophic cost flag.

HIV co-infection. Status, CD4, ART status/regimen/timing, cotrimoxazole, TB-IRIS, viral suppression, opportunistic infection.

Contact investigation. Household contacts, screening, secondary attack rate, contact LTBI/active TB, LTBI treatment cascade, transmission cluster (WGS, SNP distance).

Pharmacokinetics. NAT2 acetylator status, rifampicin/isoniazid/bedaquiline/linezolid PK, QTcF baseline & on-treatment, CYP3A4 interaction, exposure quartile, hepatotoxicity score.

Health system. Facility level, TB program type, notification channel, distance & transport cost, food/social support.

Files

hc_res_004_sample.csv — 500-patient sample (138 columns)
generate_sample_dataset_hc_res_004.py — reproducible generator + validation harness
validation_report.json / validation_report.md — full scorecard
sweep_summary.json — 6-seed determinism results

Loading

import pandas as pd
df = pd.read_csv("hc_res_004_sample.csv")
print(df[["patient_id","tb_disease_type","drug_resistance_category",
          "treatment_regimen","treatment_outcome","hiv_status"]].head())

from datasets import load_dataset
ds = load_dataset("csv", data_files="hc_res_004_sample.csv")

Use cases

TB treatment-outcome prediction across the resistance spectrum
Drug-resistance classification from molecular diagnostics (GeneXpert / LPA / WGS)
Adherence / LTFU risk modeling and DOT-strategy evaluation
HIV-TB co-infection management analytics
Contact-investigation and transmission-cluster modeling
Health-economics (catastrophic-cost, program-type) analysis
ML training where real global TB program data is access-restricted

Honest limitations & disclosed generator behavior

This is a strongly calibrated single-table engine (passes its own ~16-check suite; correct resistance-severity gradient). Standard caveats and minor specifics:

Cross-sectional episode-level table. Like the pneumonia SKU (HC-RES-003), each row is one TB episode; the monthly smear series is encoded as a pipe-delimited string field rather than a separate longitudinal table.
Latent linezolid-neuropathy switch is inert. In the outcome module, the linezolid-related neuropathy escalation checks the disease type string rather than the regimen, so peripheral neuropathy is generated at its base rate (~12%) regardless of whether linezolid is in the regimen. This does not affect any benchmark but means LZD-specific neurotoxicity is not modeled; use the PK linezolid_trough_ug_ml field if LZD exposure is needed.
Outcome weights are largely type-conditioned. For Pre-XDR/XDR/LTBI the WHO outcome distribution is applied directly by type; DS/MDR additionally shift on adherence and conversion. Individual outcomes are therefore well-calibrated at the cohort level but not fully driven by each patient's complete feature vector.
Some flags are marginal draws. Several adverse-event and contact-cascade fields are drawn at fixed prevalences rather than jointly conditioned.

General caveat: cross-field correlations beyond those explicitly modeled may be weaker than in real cohorts. Not for clinical decision-making — research/development use only.

Commercial product comparison

Capability	This sample	Full HC-RES-004 product
Patients	500	20,000+ (configurable)
Seeds / cohorts	1	Multi-seed, reproducible
Formats	CSV	CSV + Parquet + JSON
Smear trajectory	Pipe-delimited string	Optional longitudinal table
LZD neurotoxicity	Base-rate only	Regimen-linked model
Outcome model	Type-conditioned	Full feature-driven
License	CC-BY-NC-4.0	Commercial
Support & SLA	—	Included

Full product, custom cohorts, or other respiratory SKUs (asthma, COPD, pneumonia, ILD): pradeep@xpertsystems.ai

Citation

@dataset{xpertsystems_hc_res_004_2026,
  title        = {HC-RES-004: Tuberculosis Synthetic Dataset},
  author       = {XpertSystems.ai},
  year         = {2026},
  publisher    = {XpertSystems.ai Synthetic Data Factory},
  url          = {https://xpertsystems.ai},
  note         = {Synthetic; CC-BY-NC-4.0 (sample). Calibrated to: WHO Global TB Report 2023
                  (type distribution, treatment success, HIV co-infection); STREAM trial
                  (short-course MDR-TB); TB-PRACTECAL and ACTG A5279 (BPaL/BPaLM, 1HP);
                  Lancet MDR-TB individual-patient-data meta-analysis (success/LTFU);
                  WHO 2022 mutation catalogue and drug-resistance definitions. Fourth SKU in
                  the XpertSystems Respiratory vertical.}
}

Synthetic data generated by XpertSystems.ai. Not derived from real patient records. Not for clinical use.

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