accession stringlengths 6 10 | name stringlengths 6 11 | Full Name stringlengths 1 147 ⌀ | taxon stringlengths 3 46 ⌀ | sequence stringlengths 48 2.3k | function stringlengths 11 1.34k | AlphaFoldDB stringlengths 6 10 |
|---|---|---|---|---|---|---|
Q38WP3 | DEF_LATSS | Polypeptide deformylase | Latilactobacillus | <M><I><L><M><K><D><I><I><R><E><G><N><P><T><L><R><E><I><A><Q><P><V><S><F><P><L><S><D><E><D><R><Q><L><A><A><D><M><M><T><F><L><E><N><S><Q><D><P><E><I><A><A><K><Y><Q><L><R><A><G><V><G><L><A><A><P><Q><V><D><V><S><K><Q><M><S><A><V><L><V><P><G><P><E><G><E><A><P><I><L><K><D><V><I><I><N><P><K><I><I><S><H><S><V><Q><D><A><A><L><A... | Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.<BOP> | Q38WP3 |
A8M532 | EFG_SALAI | Elongation factor G | Salinispora | <M><A><A><A><D><A><L><A><N><V><R><N><I><G><I><M><A><H><I><D><A><G><K><T><T><T><T><E><R><I><L><F><Y><T><G><I><T><Y><K><I><G><E><V><H><E><G><A><A><V><M><D><W><M><A><Q><E><Q><E><R><G><I><T><I><T><S><A><A><T><K><C><E><W><K><G><H><T><I><Q><I><I><D><T><P><G><H><V><D><F><T><V><E><V><E><R><S><L><R><V><L><D><G><A><V><A><V><Y><D... | Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respective... | A8M532 |
A4QL01 | MATK_DRANE | Intron maturase | Draba | <M><E><K><F><Q><G><Y><L><E><F><D><G><A><R><Q><Q><S><F><L><Y><P><L><F><F><R><E><Y><I><Y><V><L><A><Y><D><H><G><L><N><R><L><N><R><N><R><S><I><F><V><E><N><S><D><Y><E><K><K><Y><S><S><L><I><V><K><R><L><I><W><R><M><Y><E><Q><N><R><L><I><I><P><T><T><D><L><H><K><N><P><V><L><G><H><T><N><H><L><Y><Y><Q><M><I><S><V><L><F><A><V><I><V... | Usually encoded in the trnK tRNA gene intron. Probably assists in splicing its own and other chloroplast group II introns.<BOP> | A4QL01 |
Q0W6V4 | COFH_METAR | FO synthase subunit 2 | Methanocella | <M><L><K><D><I><Y><E><R><S><L><S><G><E><I><T><I><E><D><A><R><K><L><L><E><A><N><P><F><E><L><F><D><T><A><D><Q><L><R><K><E><I><V><G><D><N><V><T><Y><I><V><N><R><N><I><N><F><T><D><F><C><V><G><T><C><K><F><C><S><F><K><N><N><K><G><F><R><L><T><L><D><E><I><L><Q><R><V><G><A><A><K><E><T><G><S><T><E><V><C><I><Q><G><G><L><T><E><D><M... | Catalyzes the radical-mediated synthesis of 5-amino-5-(4-hydroxybenzyl)-6-(D-ribitylimino)-5,6-dihydrouracil from 5-amino-6-(D-ribitylamino)uracil and L-tyrosine.<BOP> | Q0W6V4 |
Q8BSN5 | PHF23_MOUSE | PDH-containing protein JUNE-1 | Mus | <M><L><E><A><M><A><E><P><S><P><E><D><P><P><P><T><L><K><P><E><T><Q><P><P><E><K><R><R><R><T><I><E><D><F><N><K><F><C><S><F><V><L><A><Y><A><G><Y><I><P><P><S><K><E><E><S><D><W><P><A><S><G><S><S><S><P><L><R><G><E><S><A><A><D><S><D><G><W><D><S><A><P><S><D><L><R><T><I><Q><T><F><V><K><K><A><K><S><S><K><R><R><A><V><Q><S><G><P><T... | Acts as a negative regulator of autophagy, through promoting ubiquitination and degradation of LRSAM1, an E3 ubiquitin ligase that promotes autophagy in response to starvation or infecting bacteria.<BOP> | Q8BSN5 |
P97379 | G3BP2_MOUSE | GAP SH3 domain-binding protein 2 | Mus | <M><V><M><E><K><P><S><P><L><L><V><G><R><E><F><V><R><Q><Y><Y><T><L><L><N><K><A><P><E><Y><L><H><R><F><Y><G><R><N><S><S><Y><V><H><G><G><V><D><A><S><G><K><P><Q><E><A><V><Y><G><Q><N><D><I><H><H><K><V><L><S><L><N><F><S><E><C><H><T><K><I><R><H><V><D><A><H><A><T><L><S><D><G><V><V><V><Q><V><M><G><L><L><S><N><S><G><Q><P><E><R><K... | Scaffold protein that plays an essential role in cytoplasmic stress granule formation which acts as a platform for antiviral signaling.<BOP> | P97379 |
Q6GGV2 | CCA_STAAR | tRNA-NT | Staphylococcus | <M><D><K><S><L><F><E><Q><A><R><P><I><L><E><Q><I><Q><D><N><G><F><E><A><Y><Y><V><G><G><S><V><R><D><Y><V><M><G><R><N><I><H><D><I><D><I><T><T><S><A><T><P><D><E><I><E><S><I><F><S><H><T><I><P><V><G><K><E><H><G><T><I><N><V><V><F><N><D><E><N><Y><E><V><T><T><F><R><A><E><E><D><Y><V><D><H><R><R><P><S><G><V><T><F><V><R><D><L><Y><E... | Catalyzes the addition and repair of the essential 3'-terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate.<BOP> | Q6GGV2 |
P57805 | RNC_PASMU | Ribonuclease III | Pasteurella | <M><T><Q><N><L><E><R><L><Q><R><Q><I><G><Y><Q><F><N><Q><P><A><L><L><K><Q><A><L><T><H><R><S><A><A><V><K><H><N><E><R><L><E><F><L><G><D><A><I><L><N><F><I><I><A><E><A><L><Y><H><Q><F><P><K><C><N><E><G><E><L><S><R><M><R><A><T><L><V><R><E><P><T><L><A><S><L><A><R><Q><F><E><L><G><D><Y><L><S><L><G><P><G><E><L><K><S><G><G><F><R><R... | CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading n... | P57805 |
P80098 | CCL7_HUMAN | Small-inducible cytokine A7 | Homo | <M><K><A><S><A><A><L><L><C><L><L><L><T><A><A><A><F><S><P><Q><G><L><A><Q><P><V><G><I><N><T><S><T><T><C><C><Y><R><F><I><N><K><K><I><P><K><Q><R><L><E><S><Y><R><R><T><T><S><S><H><C><P><R><E><A><V><I><F><K><T><K><L><D><K><E><I><C><A><D><P><T><Q><K><W><V><Q><D><F><M><K><H><L><D><K><K><T><Q><T><P><K><L> | Chemotactic factor that attracts monocytes and eosinophils, but not neutrophils. Augments monocyte anti-tumor activity. Also induces the release of gelatinase B. This protein can bind heparin. Binds to CCR1, CCR2 and CCR3.<BOP> | P80098 |
Q8CXQ7 | CH60_MALP2 | Chaperonin-60 | Malacoplasma | <M><A><K><E><I><K><F><S><D><S><A><R><N><K><L><F><N><G><V><Q><Q><L><F><D><A><V><K><V><T><M><G><P><R><G><R><N><V><L><I><Q><K><S><Y><G><A><P><V><I><T><K><D><G><V><S><V><A><K><E><V><D><L><T><N><P><I><E><N><M><G><A><Q><L><V><K><D><V><A><S><K><T><A><D><E><A><G><D><G><T><T><T><A><T><V><L><A><Y><G><V><F><K><E><G><L><R><N><V><I... | Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.<BOP> | Q8CXQ7 |
B1JAJ9 | RS14_PSEPW | 30S ribosomal protein S14 | Pseudomonas | <M><A><K><K><S><M><K><N><R><E><L><K><R><Q><L><T><V><A><K><F><A><K><K><R><A><E><L><K><A><T><I><V><N><L><N><A><S><P><E><E><R><F><A><A><V><V><A><L><Q><K><Q><P><R><D><A><S><A><A><R><L><R><N><R><C><R><L><T><G><R><P><H><G><V><Y><R><K><F><G><L><G><R><N><M><L><R><Q><A><A><M><R><G><D><V><P><G><L><V><K><A><S><W> | Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.<BOP> | B1JAJ9 |
B3H5A9 | PCEP6_ARATH | C-terminally encoded peptide 6.2 | Arabidopsis | <M><K><L><S><V><Y><I><I><L><S><I><L><F><I><S><T><V><F><Y><E><I><Q><F><T><E><A><R><Q><L><R><K><T><D><D><Q><D><H><D><D><H><H><F><T><V><G><Y><T><D><D><F><G><P><T><S><P><G><N><S><P><G><I><G><H><K><M><K><E><N><E><E><N><A><G><G><Y><K><D><D><F><E><P><T><T><P><G><H><S><P><G><V><G><H><A><V><K><N><N><E><P><N><A> | Extracellular signaling peptide that represses primary root growth rate. Modulates leaf morphology . Regulates systemic nitrogen (N)-demand signaling. Mediates up-regulation of genes involved in N uptake and assimilation pathways .<BOP> | B3H5A9 |
Q8YLZ0 | RNZ_NOSS1 | tRNase Z | Nostoc | <M><Q><I><T><F><L><G><T><S><S><G><V><P><T><R><A><R><N><V><S><S><V><A><L><R><L><P><Q><R><A><E><L><W><L><F><D><C><G><E><G><T><Q><H><Q><I><L><R><S><D><L><K><V><S><Q><L><S><R><I><F><I><T><H><L><H><G><D><H><I><F><G><L><M><G><L><L><A><S><C><G><L><A><G><N><V><Q><R><V><D><I><Y><G><P><S><G><L><N><D><Y><I><Q><S><A><S><R><Y><S><H... | Zinc phosphodiesterase, which displays some tRNA 3'-processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA.<BOP> | Q8YLZ0 |
Q6ZIK5 | GRF4_ORYSJ | Transcription activator GRF4 | Oryza sativa | <M><A><M><P><Y><A><S><L><S><P><A><V><A><D><H><R><S><S><P><A><A><A><T><A><S><L><L><P><F><C><R><S><T><P><L><S><A><G><G><G><G><V><A><M><G><E><D><A><P><M><T><A><R><W><P><P><A><A><A><A><R><L><P><P><F><T><A><A><Q><Y><E><E><L><E><Q><Q><A><L><I><Y><K><Y><L><V><A><G><V><P><V><P><P><D><L><V><L><P><I><R><R><G><L><D><S><L><A><A><R... | Transcription activator that plays a role in the regulation of meristematic function in leaves, stems and inflorescences . Transcription activator that plays a regulatory role in grain development . Positively regulates grain size by promoting cell division and expansion, leading to increased grain length and width . P... | Q6ZIK5 |
Q4L5P8 | LSPA_STAHJ | Signal peptidase II | Staphylococcus | <M><K><K><K><Y><Y><I><T><I><S><L><I><V><A><I><A><I><L><I><I><D><Q><V><T><K><R><I><I><A><T><T><M><N><I><G><D><S><Y><E><V><I><P><N><F><L><N><I><T><S><H><R><N><N><G><A><A><W><G><I><L><S><G><K><M><G><F><F><Y><I><I><T><I><V><I><L><I><V><L><V><L><F><Y><I><K><E><A><K><Y><N><L><F><M><Q><V><A><I><S><L><L><F><A><G><A><L><G><N><F... | This protein specifically catalyzes the removal of signal peptides from prolipoproteins.<BOP> | Q4L5P8 |
Q93V99 | PDF2_ARATH | Homeodomain transcription factor PDF2 | Arabidopsis | <M><Y><H><P><N><M><F><E><S><H><H><M><F><D><M><T><P><K><S><T><S><D><N><D><L><G><I><T><G><S><R><E><D><D><F><E><T><K><S><G><T><E><V><T><T><E><N><P><S><G><E><E><L><Q><D><P><S><Q><R><P><N><K><K><K><R><Y><H><R><H><T><Q><R><Q><I><Q><E><L><E><S><F><F><K><E><C><P><H><P><D><D><K><Q><R><K><E><L><S><R><D><L><N><L><E><P><L><Q><V><K... | Probable transcription factor that binds to the L1 box DNA sequence 5'-TAAATG[CT]A-3'. Plays a role in maintaining the identity of L1 cells, possibly by interacting with their L1 box or other target-gene promoters; binds to the LIP1 gene promoter and stimulates its expression upon imbibition . Acts as a positive regula... | Q93V99 |
P40423 | SQH_DROME | Protein spaghetti-squash | Sophophora | <M><S><S><R><K><T><A><G><R><R><A><T><T><K><K><R><A><Q><R><A><T><S><N><V><F><A><M><F><D><Q><A><Q><I><A><E><F><K><E><A><F><N><M><I><D><Q><N><R><D><G><F><V><E><K><E><D><L><H><D><M><L><A><S><L><G><K><N><P><T><D><D><Y><L><D><G><M><M><N><E><A><P><G><P><I><N><F><T><M><F><L><T><L><F><G><E><R><L><Q><G><T><D><P><E><D><V><I><K><N... | Required for cytokinesis, could regulate contractile ring function.<BOP> | P40423 |
P18289 | JRA_DROME | dJun | Sophophora | <M><K><T><P><V><S><A><A><A><N><L><S><I><Q><N><A><G><S><S><G><A><T><A><I><Q><I><I><P><K><T><E><P><V><G><E><E><G><P><M><S><L><D><F><Q><S><P><N><L><N><T><S><T><P><N><P><N><K><R><P><G><S><L><D><L><N><S><K><S><A><K><N><K><R><I><F><A><P><L><V><I><N><S><P><D><L><S><S><K><T><V><N><T><P><D><L><E><K><I><L><L><S><N><N><L><M><Q><T... | Transcription factor that recognizes and binds to the enhancer heptamer motif 5'-TGA[CG]TCA-3' . Plays a role in dorsal closure .<BOP> | P18289 |
Q5ZJI0 | TPST2_CHICK | Tyrosylprotein sulfotransferase 2 | Gallus | <M><R><V><T><M><R><R><V><L><L><A><V><G><S><V><V><A><L><M><V><T><L><H><L><G><Q><Q><V><L><E><C><Q><H><V><L><S><K><R><R><H><R><L><M><R><P><E><N><E><E><L><V><M><V><D><S><N><H><V><E><Y><R><Y><S><K><E><M><P><L><I><F><I><G><G><V><P><R><S><G><T><T><L><M><R><A><M><L><D><A><H><P><E><V><R><C><G><E><E><T><R><I><I><P><R><V><L><A><M... | Catalyzes the O-sulfation of tyrosine residues within acidic motifs of polypeptides, using 3'-phosphoadenylyl sulfate (PAPS) as cosubstrate.<BOP> | Q5ZJI0 |
O64969 | CADH_EUCGL | Probable cinnamyl alcohol dehydrogenase | Eucalyptus | <M><G><S><L><E><K><E><R><T><T><T><G><W><A><A><R><D><P><S><G><V><L><S><P><Y><T><Y><S><L><R><N><T><G><P><E><D><L><Y><I><K><V><L><S><C><G><I><C><H><S><D><I><H><Q><I><K><N><D><L><G><M><S><H><Y><P><M><V><P><G><H><E><V><V><G><E><V><L><E><V><G><S><E><V><T><K><Y><R><V><G><D><R><V><G><T><G><I><V><V><G><C><C><R><S><C><S><P><C><N... | Involved in lignin biosynthesis. Catalyzes the final step specific for the production of lignin monomers. Catalyzes the NADPH-dependent reduction of coniferaldehyde, 5-hydroxyconiferaldehyde, sinapaldehyde, 4-coumaraldehyde and caffeyl aldehyde to their respective alcohols.<BOP> | O64969 |
Q2A564 | UBIA_FRATH | 4-HB polyprenyltransferase | Francisella | <M><N><K><Q><Q><L><K><A><Y><F><M><L><M><R><L><H><R><P><I><P><I><L><L><I><L><W><P><T><L><T><A><L><V><L><A><S><H><G><L><P><D><I><S><Y><L><V><I><F><T><I><G><V><V><V><M><R><T><V><G><C><I><I><N><D><I><A><D><V><D><F><D><K><H><V><A><R><T><N><T><R><P><L><T><S><G><Q><L><S><I><K><N><A><I><W><L><C><I><S><L><T><L><V><A><F><I><C><V... | Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3-octaprenyl-4-... | Q2A564 |
Q9ESC2 | TNMD_RAT | Myodulin | Rattus | <M><A><K><N><P><P><E><N><C><E><G><C><H><I><L><N><A><E><A><L><K><S><K><K><I><R><K><S><L><K><I><C><G><L><V><F><G><I><L><A><L><T><L><I><V><L><F><W><G><S><K><H><F><W><P><E><V><S><K><K><T><Y><G><M><E><H><T><F><Y><S><N><G><E><K><K><K><I><S><M><E><I><D><P><I><T><R><T><E><I><F><R><S><G><N><G><T><D><E><T><L><E><V><H><D><F><K><N... | May be an angiogenesis inhibitor.<BOP> | Q9ESC2 |
Q1WUJ3 | FOLD_LIGS1 | Methenyltetrahydrofolate cyclohydrolase | Ligilactobacillus | <M><V><A><T><I><L><D><G><R><M><L><S><K><K><I><R><T><N><V><S><E><K><V><S><L><L><K><Q><E><G><I><T><P><K><L><V><V><I><L><V><G><E><D><P><A><S><Q><V><Y><V><R><N><K><R><K><T><A><H><A><L><G><I><E><A><V><D><I><R><L><P><E><N><V><E><E><D><E><L><I><R><L><I><D><E><L><N><S><D><G><T><V><H><G><I><L><V><Q><L><P><L><P><K><H><I><N><E><N... | Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.<BOP> | Q1WUJ3 |
Q39127 | TINY_ARATH | Ethylene-responsive transcription factor TINY | Arabidopsis | <M><I><A><S><E><S><T><K><S><W><E><A><S><A><V><R><Q><E><N><E><E><E><K><K><K><P><V><K><D><S><G><K><H><P><V><Y><R><G><V><R><K><R><N><W><G><K><W><V><S><E><I><R><E><P><R><K><K><S><R><I><W><L><G><T><F><P><S><P><E><M><A><A><R><A><H><D><V><A><A><L><S><I><K><G><A><S><A><I><L><N><F><P><D><L><A><G><S><F><P><R><P><S><S><L><S><P><R... | Putative transcriptional activator.<BOP> | Q39127 |
P26308 | GBB1_DROME | Guanine nucleotide-binding protein subunit beta-1 | Sophophora | <M><N><E><L><D><S><L><R><Q><E><A><E><S><L><K><N><A><I><R><D><A><R><K><A><A><C><D><T><S><L><L><Q><A><A><T><S><L><E><P><I><G><R><I><Q><M><R><T><R><R><T><L><R><G><H><L><A><K><I><Y><A><M><H><W><G><N><D><S><R><N><L><V><S><A><S><Q><D><G><K><L><I><V><W><D><S><H><T><T><N><K><V><H><A><I><P><L><R><S><S><W><V><M><T><C><A><Y><A><P... | Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.<BOP> | P26308 |
P68350 | DOF15_ARATH | Dof zinc finger protein DOF1.5 | Arabidopsis | <M><A><T><Q><D><S><Q><G><I><K><L><F><G><K><T><I><T><F><N><A><N><I><T><Q><T><I><K><K><E><E><Q><Q><Q><Q><Q><Q><P><E><L><Q><A><T><T><A><V><R><S><P><S><S><D><L><T><A><E><K><R><P><D><K><I><I><P><C><P><R><C><K><S><M><E><T><K><F><C><Y><F><N><N><Y><N><V><N><Q><P><R><H><F><C><K><G><C><Q><R><Y><W><T><A><G><G><A><L><R><N><V><P><V... | Transcription factor that binds specifically to a 5'-AA[AG]G-3' consensus core sequence. Acts as a negative regulator in the phytochrome-mediated light responses. Controls phyB-mediated end-of-day response and the phyA-mediated anthocyanin accumulation. Not involved in direct flowering time regulation.<BOP> | P68350 |
Q635P1 | MTNB_BACCZ | Methylthioribulose-1-phosphate dehydratase | Bacillus cereus group | <M><K><Q><L><F><R><Q><W><Y><D><L><S><E><I><K><K><E><L><T><T><R><N><W><F><P><A><T><S><G><N><I><S><I><K><V><S><H><E><P><L><T><F><L><I><T><A><S><G><K><D><K><T><K><T><T><P><D><D><F><L><L><V><D><H><L><G><V><P><V><L><E><T><E><L><R><P><S><A><E><T><I><L><H><T><H><I><Y><N><N><T><N><A><G><C><V><L><H><I><H><T><T><D><N><N><V><I><T... | Catalyzes the dehydration of methylthioribulose-1-phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P).<BOP> | Q635P1 |
B7UNY1 | TORD_ECO27 | Chaperone protein TorD | Escherichia | <M><T><T><L><T><A><Q><Q><I><A><C><V><Y><A><W><L><A><Q><L><F><S><R><E><L><D><D><E><Q><L><T><Q><I><A><S><A><Q><M><A><E><W><F><S><L><L><K><S><E><P><P><L><T><A><A><V><N><G><L><E><N><S><I><A><T><L><T><V><R><D><D><A><R><L><E><L><A><A><D><F><C><G><L><F><L><M><T><D><K><Q><A><A><L><P><Y><A><S><A><N><K><Q><D><E><Q><E><I><K><R><L... | Involved in the biogenesis of TorA. Acts on TorA before the insertion of the molybdenum cofactor and, as a result, probably favors a conformation of the apoenzyme that is competent for acquiring the cofactor.<BOP> | B7UNY1 |
B2V704 | LPXB_SULSY | Lipid-A-disaccharide synthase | unclassified Sulfurihydrogenibium | <M><K><K><I><F><L><S><V><G><E><I><S><G><D><N><Y><A><S><E><L><A><K><H><L><K><E><Y><Q><I><T><G><I><T><G><P><K><M><R><A><I><G><V><K><P><V><A><N><L><E><D><I><S><V><V><G><L><T><E><A><L><S><K><Y><K><K><I><K><E><V><F><K><Q><S><V><Q><A><L><K><S><G><V><D><L><L><I><V><V><D><F><P><G><F><N><I><K><L><L><K><E><A><K><K><L><G><I><K><T... | Condensation of UDP-2,3-diacylglucosamine and 2,3-diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.<BOP> | B2V704 |
P02651 | APOA4_RAT | Apolipoprotein A4 | Rattus | <M><F><L><K><A><V><V><L><T><V><A><L><V><A><I><T><G><T><Q><A><E><V><T><S><D><Q><V><A><N><V><M><W><D><Y><F><T><Q><L><S><N><N><A><K><E><A><V><E><Q><L><Q><K><T><D><V><T><Q><Q><L><N><T><L><F><Q><D><K><L><G><N><I><N><T><Y><A><D><D><L><Q><N><K><L><V><P><F><A><V><Q><L><S><G><H><L><T><K><E><T><E><R><V><R><E><E><I><Q><K><E><L><E... | May have a role in chylomicrons and VLDL secretion and catabolism. Required for efficient activation of lipoprotein lipase by ApoC-II; potent activator of LCAT. Apoa-IV is a major component of HDL and chylomicrons.<BOP> | P02651 |
A8G797 | PEBB_PROM2 | Phycoerythrobilin:ferredoxin oxidoreductase | Prochlorococcus | <M><L><I><K><D><T><I><F><Y><R><P><D><W><R><W><H><I><F><L><K><Y><L><T><N><N><L><S><K><Y><N><C><L><E><K><I><I><P><S><E><Y><S><Y><K><D><S><T><Y><G><S><K><K><S><K><K><N><V><N><L><C><T><W><G><V><T><H><K><K><R><I><Q><F><A><R><A><V><C><I><N><S><P><K><Y><S><V><L><N><F><L><I><I><P><N><T><I><Y><N><V><P><F><F><G><V><D><F><V><S><L... | Catalyzes the two-electron reduction of the C2 and C3(1) diene system of 15,16-dihydrobiliverdin.<BOP> | A8G797 |
Q02QU5 | MNMC_PSEAB | FAD-dependent cmnm(5)s(2)U34 oxidoreductase | Pseudomonas | <M><S><D><F><Q><H><A><Q><L><D><W><D><E><N><G><Q><P><L><S><R><A><F><G><D><V><Y><F><S><R><H><S><G><L><N><E><T><R><H><V><F><L><A><T><N><R><L><A><E><R><F><A><A><L><G><D><G><E><V><L><C><I><G><E><T><G><F><G><T><G><L><N><F><L><C><A><W><Q><L><F><E><Q><V><A><P><A><G><A><R><L><E><F><V><S><V><E><K><F><P><L><A><A><A><D><L><R><R><A... | Catalyzes the last two steps in the biosynthesis of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s... | Q02QU5 |
P13678 | KPC3_DROME | dPKC98F | Sophophora | <M><F><T><G><K><L><Q><I><K><V><C><E><A><S><G><L><R><P><T><D><F><Q><K><R><H><N><L><T><F><G><K><L><A><D><E><Q><L><I><D><P><Y><V><S><I><D><V><D><E><S><H><F><D><R><A><T><T><R><P><K><T><F><D><P><V><W><N><E><Q><F><V><H><D><V><T><N><V><S><N><I><N><L><T><V><F><H><D><A><A><L><P><P><D><D><F><V><A><N><C><I><I><S><F><E><D><L><M><Q... | PKC is activated by diacylglycerol which in turn phosphorylates a range of cellular proteins. PKC also serves as the receptor for phorbol esters, a class of tumor promoters.<BOP> | P13678 |
Q1RJJ2 | YIDD_RICBR | Putative membrane protein insertion efficiency factor | belli group | <M><T><R><I><L><L><L><L><L><T><F><Y><R><Y><F><I><S><P><L><L><G><G><N><N><C><R><F><Y><P><T><C><S><K><Y><A><K><E><A><L><N><T><H><G><G><I><K><G><L><W><L><I><F><K><R><I><I><K><C><Q><P><L><C><D><G><G><Y><D><P><V><P><L><T><K> | Could be involved in insertion of integral membrane proteins into the membrane.<BOP> | Q1RJJ2 |
P12626 | ANFA_AZOVI | Nitrogen fixation protein AnfA | Azotobacter | <M><S><D><Q><A><T><F><E><F><D><T><D><Y><F><V><E><E><F><S><H><C><F><T><G><E><C><R><V><K><M><L><P><I><L><Y><K><I><S><Q><I><I><T><G><N><A><D><L><A><D><A><L><S><I><V><L><G><V><M><Q><Q><H><L><K><M><Q><R><G><I><V><T><L><Y><D><M><R><A><E><T><I><F><I><H><D><S><F><G><L><T><E><E><E><K><K><R><G><I><Y><A><V><G><E><G><I><T><G><K><V... | AnfA is essential for nitrogen fixation under Mo- and V-deficient conditions. It is required for the regulation of nitrogenase 3 transcription. Interacts with sigma-54.<BOP> | P12626 |
Q8ZPZ4 | MNMA_SALTY | tRNA-specific 2-thiouridylase MnmA | Salmonella | <M><S><E><S><P><K><K><V><I><V><G><M><S><G><G><V><D><S><S><V><S><A><W><L><L><Q><Q><Q><G><Y><Q><V><E><G><L><F><M><K><N><W><E><E><D><D><G><E><E><Y><C><T><A><A><A><D><L><A><D><A><Q><A><V><C><D><K><L><G><I><E><L><H><T><V><N><F><A><A><E><Y><W><D><N><V><F><E><L><F><L><E><E><Y><K><A><G><R><T><P><N><P><D><I><L><C><N><K><E><I><K... | Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA(Lys), tRNA(Glu) and tRNA(Gln), leading to the formation of s(2)U34, the first step of tRNA-mnm(5)s(2)U34 synthesis. Sulfur is provided by IscS, via a sulfur-relay system. Binds ATP and its substrate tRNAs.<BOP> | Q8ZPZ4 |
B9E9J2 | RL4_MACCJ | 50S ribosomal protein L4 | Macrococcus | <M><A><N><Y><D><V><L><K><V><D><G><T><K><A><G><S><I><E><L><N><D><N><V><F><G><I><E><P><N><Q><H><V><L><F><E><A><I><N><L><Q><R><A><S><M><R><Q><G><T><H><A><V><K><N><R><S><A><V><S><G><G><G><R><K><P><W><K><Q><K><G><T><G><R><A><R><Q><G><T><I><R><A><P><Q><W><R><G><G><G><I><V><F><G><P><T><P><R><S><Y><S><Y><K><M><P><K><K><M><R><R... | Forms part of the polypeptide exit tunnel.<BOP> | B9E9J2 |
Q93YV6 | 2A5K_ARATH | Serine/threonine protein phosphatase 2A 57 kDa regulatory subunit B' kappa isoform | Arabidopsis | <M><F><K><Q><F><L><S><K><L><P><R><K><S><S><K><S><D><S><G><E><L><N><R><S><S><S><G><P><V><S><S><P><V><Q><R><S><G><T><S><G><G><G><S><G><P><V><R><S><N><S><G><K><R><M><S><S><A><V><F><P><A><S><V><V><A><G><I><E><P><L><V><P><F><K><D><V><P><S><S><E><K><L><N><L><F><V><S><K><V><S><L><C><C><V><T><F><D><F><S><D><P><G><K><N><S><I><E... | The B regulatory subunit may modulate substrate selectivity and catalytic activity, and may also direct the localization of the catalytic enzyme to a particular subcellular compartment.<BOP> | Q93YV6 |
Q5L5H5 | IF1_CHLAB | Translation initiation factor IF-1 | Chlamydia | <M><A><K><K><E><D><T><I><V><L><E><G><R><V><K><E><L><L><P><G><M><H><F><K><I><L><L><E><N><G><M><P><V><T><A><H><L><C><G><K><M><R><M><S><N><I><R><L><L><V><G><D><R><V><T><V><E><M><S><A><Y><D><L><T><K><A><R><V><V><Y><R><H><R> | One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-... | Q5L5H5 |
C6DYJ5 | SYT_GEOSM | Threonyl-tRNA synthetase | unclassified Geobacter | <M><N><E><I><N><V><T><L><P><D><G><S><Q><R><P><L><P><A><G><A><S><I><F><D><L><A><A><S><I><G><A><G><L><A><K><A><A><I><A><G><K><I><D><G><N><L><V><D><L><N><T><P><L><A><D><G><A><R><V><E><I><V><T><E><K><S><P><E><A><L><E><I><I><R><H><S><T><S><H><L><M><A><Q><A><V><K><A><L><F><P><Q><A><K><V><T><I><G><P><A><I><E><T><G><F><Y><Y><D... | Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction: L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr). Also edits incorrectly charged L-seryl-tRNA(Thr).<BOP> | C6DYJ5 |
B8J9V9 | RRF_ANAD2 | Ribosome-releasing factor | Anaeromyxobacter | <M><G><T><I><A><D><D><I><L><D><D><L><H><G><R><I><L><K><T><L><D><Q><L><R><T><E><L><A><A><V><R><T><G><R><A><S><L><H><L><L><D><N><V><R><V><D><Y><Y><G><T><P><T><P><L><N><Q><V><A><T><L><S><V><P><E><A><R><L><I><V><V><K><P><W><E><K><S><M><I><P><P><I><E><K><A><I><R><D><G><N><L><G><L><N><P><M><S><D><K><D><L><V><R><V><P><I><P><A... | Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another.<BOP> | B8J9V9 |
Q2RI73 | AROC_MOOTA | 5-enolpyruvylshikimate-3-phosphate phospholyase | Moorella | <M><L><R><Y><L><T><A><G><E><S><H><G><R><G><L><S><V><I><V><E><G><L><P><A><G><V><P><L><T><D><G><D><I><N><T><W><L><T><R><R><Q><G><G><Y><G><R><G><G><R><M><A><I><E><R><D><Q><A><E><I><L><A><G><V><R><G><G><L><T><L><G><S><P><I><A><L><F><I><A><N><R><D><W><E><N><W><Q><E><I><M><A><P><G><P><E><A><R><A><A><R><V><V><T><R><P><R><P><G... | Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a s... | Q2RI73 |
O22456 | SEP3_ARATH | Agamous-like MADS-box protein AGL9 | Arabidopsis | <M><G><R><G><R><V><E><L><K><R><I><E><N><K><I><N><R><Q><V><T><F><A><K><R><R><N><G><L><L><K><K><A><Y><E><L><S><V><L><C><D><A><E><V><A><L><I><I><F><S><N><R><G><K><L><Y><E><F><C><S><S><S><S><M><L><R><T><L><E><R><Y><Q><K><C><N><Y><G><A><P><E><P><N><V><P><S><R><E><A><L><A><V><E><L><S><S><Q><Q><E><Y><L><K><L><K><E><R><Y><D><A... | Probable transcription factor active in inflorescence development and floral organogenesis. Functions with SEPALLATA1/AGL2 and SEPALLATA2/AGL4 to ensure proper development of petals, stamens and carpels and to prevent the indeterminate growth of the flower meristem. Interacts with APETALA1, AGAMOUS or APETALA3/PISTILLA... | O22456 |
Q6DW73 | DGDG2_LOTJA | Digalactosyldiacylglycerol synthase 2, chloroplastic | Lotus | <M><G><K><K><Q><H><I><A><I><F><T><T><A><S><L><P><W><L><T><G><T><A><V><N><P><L><F><R><A><A><Y><L><S><K><D><G><E><R><D><V><T><L><V><I><P><W><L><S><L><K><D><Q><A><L><V><Y><P><N><N><I><T><F><A><S><P><S><E><H><E><K><Y><I><R><Q><W><L><E><E><R><V><G><F><T><S><G><F><S><I><K><F><Y><P><G><K><F><S><R><D><K><R><S><I><L><A><V><G><D... | Involved in the synthesis of diacylglycerol galactolipids that are specifically found in thylakoid membranes. Specific for alpha-glycosidic linkages.<BOP> | Q6DW73 |
Q49588 | PSTB_MYCIT | Phosphate-transporting ATPase | Mycobacterium avium complex (MAC) | <M><R><R><E><Q><Q><L><P><A><A><V><A><A><P><V><A><D><G><G><Q><L><M><R><A><V><D><L><T><L><G><F><G><P><K><T><V><L><E><Q><V><S><L><D><F><P><A><R><S><V><T><T><L><L><G><P><T><G><S><G><K><T><T><F><L><R><T><L><N><R><M><N><D><K><V><S><G><F><R><H><S><G><D><V><L><L><G><G><R><T><I><F><A><D><R><D><L><M><E><F><R><R><S><V><G><M><L><F... | Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system.<BOP> | Q49588 |
F4HU58 | TAD1_ARATH | tRNA-specific adenosine-37 deaminase TAD1 | Arabidopsis | <M><E><E><D><W><G><K><T><V><S><E><K><V><I><S><A><Y><M><S><L><P><K><K><G><K><P><Q><G><R><E><V><T><V><L><S><A><F><L><V><S><S><P><S><Q><D><P><K><V><I><A><L><G><T><G><T><K><C><V><S><G><S><L><L><S><P><R><G><D><I><V><N><D><S><H><A><E><V><V><A><R><R><A><L><I><R><F><F><Y><S><E><I><Q><R><M><Q><L><T><S><G><K><S><N><E><A><K><R><Q... | Involved in RNA editing. Catalyzes the specific deamination of adenosine-37 in the cytosolic tRNA-Ala. Generates inosine at the position 3'-adjacent to the anticodon tRNA-Ala.<BOP> | F4HU58 |
Q02953 | HSF_SCHPO | Heat shock transcription factor | Schizosaccharomyces | <M><I><Q><T><A><S><T><I><S><S><N><G><G><T><N><Q><G><M><E><S><S><S><A><N><S><P><E><M><N><G><T><Q><N><S><M><S><V><G><M><S><G><S><G><S><S><Q><N><R><K><I><T><Q><F><S><N><K><L><Y><N><M><V><N><D><S><S><T><D><S><L><I><R><W><S><D><R><G><D><S><F><L><V><I><G><H><E><D><F><A><K><L><V><L><P><R><Y><F><K><H><N><N><F><S><S><F><V><R><Q... | DNA-binding protein that specifically binds heat shock promoter elements (HSE) and activates transcription. Also required for growth at normal temperatures.<BOP> | Q02953 |
P10176 | COX8A_HUMAN | Cytochrome c oxidase subunit 8-2 | Homo | <M><S><V><L><T><P><L><L><L><R><G><L><T><G><S><A><R><R><L><P><V><P><R><A><K><I><H><S><L><P><P><E><G><K><L><G><I><M><E><L><A><V><G><L><T><S><C><F><V><T><F><L><L><P><A><G><W><I><L><S><H><L><E><T><Y><R><R><P><E> | Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CII... | P10176 |
C6A5J6 | NADK_THESM | ATP-dependent NAD kinase | Thermococcus | <M><K><F><G><I><V><A><R><R><D><R><E><E><A><L><K><L><A><Y><R><V><Y><D><F><L><K><V><N><N><Y><E><V><Y><V><D><E><E><A><Y><I><H><F><P><H><F><S><S><E><D><V><L><S><L><K><K><M><D><V><D><M><I><I><A><I><G><G><D><G><T><V><L><R><V><E><H><N><T><S><K><D><I><P><I><L><A><V><N><M><G><T><L><G><F><L><A><E><I><E><P><A><E><T><F><F><A><I><S... | Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.<BOP> | C6A5J6 |
O74499 | LSM7_SCHPO | U6 snRNA-associated Sm-like protein LSm7 | Schizosaccharomyces | <M><S><S><L><Q><K><R><P><G><P><G><N><S><S><Q><P><T><E><R><P><R><K><E><S><I><L><D><L><S><R><Y><Q><D><Q><R><I><Q><A><T><F><T><G><G><R><Q><I><T><G><I><L><K><G><F><D><Q><L><M><N><L><V><L><D><D><V><E><E><Q><L><R><N><P><E><D><G><K><L><T><G><A><I><R><K><L><G><L><V><V><V><R><G><T><T><L><V><L><I><A><P><M><D><G><S><E><E><I><P><N... | Component of LSm protein complexes, which are involved in RNA processing and may function in a chaperone-like manner. Probable component of the spliceosome.<BOP> | O74499 |
Q10271 | ARB2_SCHPO | Argonaute-binding protein 2 | Schizosaccharomyces | <M><F><R><K><K><K><S><R><V><L><Q><R><D><V><N><F><G><N><C><L><E><D><M><N><L><Q><I><T><N><D><F><Y><L><R><K><L><N><A><P><N><E><L><Y><E><F><Q><V><T><K><D><K><E><Y><N><E><K><F><Y><F><A><V><L><D><H><V><Y><S><W><T><L><Q><N><S><L><L><T><R><I><S><I><P><L><E><S><S><P><S><E><P><H><S><W><I><Y><A><T><R><N><W><Q><T><N><E><N><G><I><V... | A member of the argonaute siRNA chaperone (ARC) complex which is required for histone H3K9 methylation, heterochromatin assembly and siRNA generation. The ARC complex contains mostly double-stranded siRNA. Inhibits the release of the siRNA passenger strand from ago1 together with arb1.<BOP> | Q10271 |
B0BZK7 | ATP61_ACAM1 | F-ATPase subunit 6 1 | Acaryochloris | <M><P><L><A><S><L><E><V><G><Q><H><L><Y><W><Q><I><G><G><L><K><V><H><G><Q><V><L><I><T><S><W><I><V><I><G><I><L><V><I><V><S><V><L><A><T><R><K><V><E><R><I><P><S><G><L><Q><N><F><M><E><Y><A><L><E><F><V><R><D><L><T><K><N><Q><I><G><E><K><E><Y><R><P><W><V><P><F><I><G><T><L><F><L><F><I><F><V><S><N><W><S><G><A><L><F><P><W><K><L><I... | Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.<BOP> | B0BZK7 |
B3EGP4 | RECA_CHLL2 | Recombinase A | Chlorobium | <M><N><M><D><T><N><D><K><E><K><K><N><E><G><I><D><P><A><K><L><K><Q><L><N><L><A><V><D><A><L><E><K><Q><F><G><K><G><A><I><M><R><L><G><D><G><S><A><V><M><Q><V><Q><S><I><S><T><G><S><M><T><L><D><F><A><L><G><V><G><G><L><P><R><G><R><V><A><E><I><Y><G><P><E><S><S><G><K><T><T><L><A><L><H><V><I><A><E><A><Q><K><E><G><G><I><A><A><I><V... | Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage.<BOP> | B3EGP4 |
B9KJ95 | LIPB_ANAMF | Octanoyl-[acyl-carrier-protein]-protein N-octanoyltransferase | Anaplasma | <M><S><L><L><G><F><P><V><E><W><R><V><S><D><G><M><V><D><Y><K><A><A><L><D><F><M><T><S><R><V><D><G><I><L><E><G><R><E><S><E><M><V><W><L><L><E><H><P><S><V><Y><T><A><G><V><S><A><K><D><G><E><L><L><S><E><N><K><F><Q><V><V><R><T><T><R><G><G><K><Y><S><Y><H><G><P><G><Q><R><V><V><Y><V><M><L><H><L><G><R><R><D><K><R><D><V><R><L><Y><V... | Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate.<BOP> | B9KJ95 |
Q60CS4 | RSMG_METCA | 16S rRNA 7-methylguanosine methyltransferase | Methylococcus | <M><L><E><R><G><L><S><E><L><G><S><D><A><G><G><D><Q><R><E><R><L><L><R><F><L><E><L><L><R><K><W><N><R><V><Y><S><L><T><A><I><E><D><P><C><E><G><V><R><L><H><L><L><D><S><L><S><I><A><S><F><L><H><G><R><R><V><L><D><V><G><T><G><P><G><L><P><G><I><P><L><A><I><V><Q><P><E><R><R><F><V><L><L><D><C><N><A><K><K><I><R><F><V><R><Q><A><V><I... | Specifically methylates the N7 position of guanine in position 527 of 16S rRNA.<BOP> | Q60CS4 |
O74974 | UTP25_SCHPO | U three protein 25 | Schizosaccharomyces | <M><A><I><E><S><D><L><D><G><A><S><M><D><E><L><A><G><K><S><Y><E><A><L><L><Y><L><M><N><K><N><K><K><R><K><P><E><K><K><D><D><K><E><K><S><S><K><K><V><Q><K><K><N><K><V><I><E><S><L><N><E><M><E><V><E><M><E><D><E><N><E><N><E><N><D><E><Q><E><A><I><Q><Y><Y><I><N><V><E><S><Q><D><A><D><E><T><L><H><Q><E><A><Q><D><S><S><E><D><P><F><H... | DEAD-box RNA helicase-like protein required for pre-18S rRNA processing, specifically at sites A0, A1, and A2.<BOP> | O74974 |
Q65JA8 | HFQ_BACLD | RNA-binding protein Hfq | Bacillus | <M><K><S><I><N><I><Q><D><Q><F><L><N><Q><I><R><K><E><N><T><F><V><T><V><F><L><L><N><G><F><Q><L><R><G><Q><V><K><G><F><D><N><F><T><V><L><I><E><S><E><G><K><Q><Q><L><I><Y><K><H><A><I><S><T><F><A><P><Q><K><N><V><Q><L><E><L><E> | RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs.<BOP> | Q65JA8 |
Q9UUC7 | CTU2_SCHPO | Cytoplasmic tRNA 2-thiolation protein 2 | Schizosaccharomyces | <M><Q><N><T><A><L><D><N><S><A><D><S><K><C><S><K><C><D><N><K><A><T><V><L><T><K><S><D><A><V><C><D><S><C><F><V><R><R><I><E><N><K><I><R><R><Q><F><E><L><V><R><P><N><L><Q><G><R><K><S><K><R><A><M><L><A><I><S><G><G><I><S><S><M><A><M><L><E><T><A><N><Y><L><S><K><Y><R><D><D><N><Y><R><P><M><F><D><E><L><L><A><V><H><F><Q><W><G><T><D... | Plays a central role in 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of tRNA(Lys), tRNA(Glu) and tRNA(Gln). May act by forming a heterodimer with ctu1 that ligates sulfur from thiocarboxylated urm1 onto the uridine of tRNAs at wobble position. Prior mcm(5) tRNA modification by the elongator complex is required ... | Q9UUC7 |
C0ZAH1 | HEM3_BREBN | Pre-uroporphyrinogen synthase | Brevibacillus | <M><G><K><W><K><V><G><T><R><R><S><K><L><A><L><T><Q><T><N><W><V><V><D><K><L><K><G><F><A><P><E><A><D><F><E><L><H><E><I><V><T><K><G><D><R><I><L><D><V><T><L><S><K><V><G><G><K><G><L><F><V><K><E><I><E><Q><S><L><F><D><K><E><T><D><F><A><V><H><S><L><K><D><M><P><A><E><L><P><D><G><L><V><I><G><A><I><P><K><R><V><D><P><R><D><V><L><L... | Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.<BOP> | C0ZAH1 |
P61721 | RISB_CORDI | 6,7-dimethyl-8-ribityllumazine synthase | Corynebacterium | <M><S><K><E><G><L><P><N><V><S><S><V><A><G><A><G><L><V><V><G><I><V><S><A><T><W><N><E><K><I><C><N><Q><L><H><A><E><A><I><R><T><A><K><D><C><G><A><K><V><I><E><T><R><V><I><G><A><L><E><L><P><I><V><V><Q><K><L><A><Q><T><C><D><A><V><V><A><N><G><C><V><I><K><G><G><T><P><H><F><D><Y><V><C><D><S><V><T><E><G><L><T><R><I><A><L><D><S><G... | Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.<BOP> | P61721 |
Q2GB76 | MURA_NOVAD | UDP-N-acetylglucosamine enolpyruvyl transferase | Novosphingobium | <M><D><K><I><I><I><R><G><G><K><R><L><S><G><A><V><P><V><S><G><A><K><N><S><A><L><T><L><L><P><C><A><L><L><T><D><E><P><V><T><L><R><N><L><P><R><L><A><D><I><D><G><F><Q><H><L><M><N><Q><F><G><V><S><T><S><I><A><G><A><R><P><E><D><F><G><R><V><M><T><L><Q><A><T><R><L><T><S><T><V><A><P><Y><D><L><V><R><K><M><R><A><S><I><L><V><L><G><P... | Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine.<BOP> | Q2GB76 |
Q8LFU0 | NFYAA_ARATH | Nuclear transcription factor Y subunit A-10 | Arabidopsis | <M><Q><T><E><E><L><L><S><P><P><Q><T><P><W><W><N><A><F><G><S><Q><P><L><T><T><E><S><L><S><G><E><A><S><D><S><F><T><G><V><K><A><V><T><T><E><A><E><Q><G><V><V><D><K><Q><T><S><T><T><L><F><T><F><S><P><G><G><E><K><S><S><R><D><V><P><K><P><H><V><A><F><A><M><Q><S><A><C><F><E><F><G><F><A><Q><P><M><M><Y><T><K><H><P><H><V><E><Q><Y><Y... | Stimulates the transcription of various genes by recognizing and binding to a CCAAT motif in promoters.<BOP> | Q8LFU0 |
Q6P0U0 | NAGA_DANRE | Amidohydrolase domain-containing protein 2 | Danio | <M><P><S><N><K><S><V><S><D><A><P><I><T><Q><F><V><N><C><R><I><L><K><N><H><K><L><Q><W><E><D><L><W><V><R><E><G><K><I><L><N><P><E><K><L><F><F><D><E><Q><G><F><A><D><H><R><V><D><C><E><N><K><I><I><A><P><G><F><I><D><V><Q><L><N><G><G><Y><G><I><D><F><S><Q><A><S><S><D><I><R><G><G><V><A><L><V><A><K><K><I><L><E><H><G><V><T><S><F><C... | Hydrolyzes the N-glycolyl group from N-glycolylglucosamine 6-phosphate (GlcNGc-6-P) in the N-glycolylneuraminic acid (Neu5Gc) degradation pathway.<BOP> | Q6P0U0 |
A4Y4X5 | THII_SHEPC | tRNA 4-thiouridine synthase | Shewanella | <M><K><F><I><V><K><L><Y><P><E><I><M><M><K><S><K><P><V><R><M><R><F><T><K><M><L><E><T><N><I><R><N><V><L><K><K><V><D><E><D><A><K><V><Q><R><Q><W><D><R><I><M><V><M><V><P><K><H><K><P><E><L><A><Q><A><F><G><E><R><L><A><C><I><P><G><I><A><H><V><V><Q><V><D><E><Y><S><F><E><S><V><D><D><I><Y><Q><Q><A><L><P><V><Y><R><D><Q><I><A><G><K... | Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynt... | A4Y4X5 |
Q30YB7 | OTC_OLEA2 | Ornithine carbamoyltransferase | Oleidesulfovibrio | <M><T><K><H><F><T><Q><I><R><D><L><G><Y><Q><A><A><W><D><V><L><R><R><A><K><E><M><K><D><S><R><H><R><S><T><L><L><E><G><K><S><A><I><M><L><F><E><K><A><S><T><R><T><R><V><S><F><E><T><A><V><H><Q><L><G><G><K><T><I><F><M><T><P><A><E><S><Q><L><G><R><S><E><P><L><R><D><T><A><R><V><L><S><R><Y><N><D><L><M><I><V><R><T><F><G><Q><E><K><I... | Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline.<BOP> | Q30YB7 |
B8J031 | EFP_DESDA | Elongation factor P | Desulfovibrio | <M><Y><S><T><T><D><F><R><K><G><L><K><I><E><V><E><G><I><P><Y><E><I><V><D><F><Q><H><F><K><P><G><K><G><G><A><M><V><R><T><K><L><R><N><I><L><T><G><R><M><Q><D><I><T><F><R><S><G><E><K><V><N><K><P><D><L><E><T><R><D><M><Q><F><L><Y><R><Q><D><D><D><L><I><F><M><D><M><T><T><Y><E><Q><L><Q><M><P><V><S><T><T><D><G><K><E><G><F><L><K><D... | Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.<BOP> | B8J031 |
C5D2V2 | PROA_GEOSW | Glutamyl-gamma-semialdehyde dehydrogenase | unclassified Geobacillus | <M><N><E><L><L><I><K><A><E><Q><L><Q><Q><A><A><K><T><L><A><L><L><S><T><E><E><K><N><E><A><L><T><R><I><A><E><A><L><I><K><Q><K><E><W><I><L><Q><E><N><E><K><D><V><A><L><G><K><E><Q><G><L><S><P><A><L><I><D><R><L><Q><L><T><N><E><R><I><E><Q><I><V><D><G><V><R><Q><V><A><D><L><P><D><P><I><G><E><I><V><E><E><W><T><R><P><N><G><L><R><I... | Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate.<BOP> | C5D2V2 |
Q93V56 | IPYR1_ARATH | Pyrophosphate phospho-hydrolase 1 | Arabidopsis | <M><S><E><E><T><K><D><N><Q><R><L><Q><R><P><A><P><R><L><N><E><R><I><L><S><S><L><S><R><R><S><V><A><A><H><P><W><H><D><L><E><I><G><P><G><A><P><Q><I><F><N><V><V><V><E><I><T><K><G><S><K><V><K><Y><E><L><D><K><K><T><G><L><I><K><V><D><R><I><L><Y><S><S><V><V><Y><P><H><N><Y><G><F><V><P><R><T><L><C><E><D><N><D><P><I><D><V><L><V><I... | Catalyzes the irreversible hydrolysis of pyrophosphate (PPi) to phosphate. The MgPPi(2-) complex binds to the enzyme only after a free Mg(2+) ion has bound (Ref.9). No activity with glycerol-3-phosphate, glucose-6-phosphate, p-nitrophenylphosphate, ADP, NADP(+), NAD(+),NADH, NADPH or phosphoribosyl pyrophosphate as sub... | Q93V56 |
Q2IX94 | RL9_RHOP2 | 50S ribosomal protein L9 | Rhodopseudomonas | <M><E><V><I><L><L><E><R><V><A><K><L><G><Q><M><G><E><L><V><R><V><K><D><G><Y><A><R><N><F><L><L><P><R><G><K><A><L><R><A><T><A><A><N><R><D><K><Y><E><H><M><K><A><D><L><E><A><R><N><I><A><A><K><A><E><A><A><K><V><A><E><K><I><D><G><H><N><V><I><V><I><R><Q><A><S><E><T><G><Q><L><F><G><S><V><S><V><R><D><I><V><T><S><F><E><A><E><G><V... | Binds to the 23S rRNA.<BOP> | Q2IX94 |
Q54N80 | FKBP3_DICDI | Rotamase | Dictyostelium | <M><N><K><F><L><I><A><L><L><V><L><A><T><L><A><V><S><F><S><Q><E><I><G><V><S><I><L><K><T><D><T><P><K><G><E><C><K><G><K><T><A><S><I><G><D><Y><I><S><L><K><Y><V><G><K><F><E><D><G><T><V><F><D><S><S><E><I><H><G><G><F><S><F><N><F><T><I><G><E><R><K><V><I><P><G><L><E><I><G><T><I><N><I><C><E><G><E><K><R><S><I><K><I><P><Y><Q><L><A... | PPIases accelerate the folding of proteins by catalyzing the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.<BOP> | Q54N80 |
C5DX31 | GSM1_ZYGRC | Glucose starvation modulator protein 1 | Zygosaccharomyces | <M><T><K><K><L><S><L><E><L><R><Q><T><R><K><P><I><Q><T><A><C><G><F><C><H><E><K><H><L><Q><C><D><V><G><R><P><C><Q><N><C><R><K><R><N><I><A><S><F><C><R><D><K><V><K><R><R><R><K><R><K><R><S><D><A><S><N><F><D><K><D><E><A><A><T><Q><T><L><N><F><N><T><V><N><P><G><E><G><S><S><S><A><M><T><Q><D><E><K><N><T><G><T><T><T><A><T><T><T><R... | Transcription factor which regulates nonfermentable carbon utilization.<BOP> | C5DX31 |
P50420 | CASK_CAPSU | Kappa-casein | Capricornis | <M><M><K><S><F><F><L><V><V><T><I><L><A><L><T><L><P><F><L><G><A><Q><E><Q><N><Q><E><Q><P><I><C><C><E><K><D><E><R><F><F><D><D><K><I><A><K><Y><I><P><I><Q><Y><V><L><S><R><Y><P><S><Y><G><L><N><Y><Y><Q><Q><R><P><V><A><L><I><N><N><Q><F><L><P><Y><P><Y><Y><A><K><P><V><A><V><R><S><P><A><Q><T><L><Q><W><Q><V><L><P><N><T><A><P><A><K... | Kappa-casein stabilizes micelle formation, preventing casein precipitation in milk.<BOP> | P50420 |
P87020 | PRA1_CANAL | 58 kDa fibrinogen-binding mannoprotein | Candida | <M><N><Y><L><L><F><C><L><F><F><A><F><S><V><A><A><P><V><T><V><T><R><F><V><D><A><S><P><T><G><Y><D><W><R><A><D><W><V><K><G><F><P><I><D><S><S><C><N><A><T><Q><Y><N><Q><L><S><T><G><L><Q><E><A><Q><L><L><A><E><H><A><R><D><H><T><L><R><F><G><S><K><S><P><F><F><R><K><Y><F><G><N><E><T><A><S><A><E><V><V><G><H><F><D><N><V><V><G><A><D... | Cell surface protein involved in the host-parasite interaction during candidal infection. With MP65, represents a major component of the biofilm matrix. Sequesters zinc from host tissue and mediates leukocyte adhesion and migration. As a surface protein, binds the two human complement regulators CFH and CFHR1, as well ... | P87020 |
P24377 | GVPM1_HALSA | Gas vesicle protein GvpM 1 | Halobacterium | <M><E><P><T><K><D><E><T><H><A><I><V><E><F><V><D><V><L><L><R><D><G><A><V><I><Q><A><D><V><I><V><T><V><A><D><I><P><L><I><G><I><S><L><R><A><A><I><A><G><M><T><T><M><T><E><Y><G><L><F><E><E><W><D><A><A><H><R><Q><Q><S><E><A><F><T><T><S><P><T><A><D><R><R><E><D> | Gas vesicles are small, hollow, gas filled protein structures that are found in several microbial planktonic microorganisms. They allow the positioning of the organism at the favorable depth for growth. This protein could be important for the shape determination of the gas vesicle.<BOP> | P24377 |
P0A1K8 | SPAO_SALEN | Surface presentation of antigens protein SpaO | Salmonella | <M><S><L><R><V><R><Q><I><D><R><R><E><W><L><L><A><Q><T><A><T><E><C><Q><R><H><G><Q><E><A><T><L><E><Y><P><T><R><Q><G><M><W><V><R><L><S><D><A><E><K><R><W><S><A><W><I><Q><P><G><D><W><L><E><H><V><S><P><A><L><A><G><A><A><V><S><A><G><A><E><H><L><V><V><P><W><L><A><A><T><E><R><P><F><E><L><P><V><P><H><L><S><C><R><R><L><C><V><E><N... | Involved in a secretory pathway responsible for the surface presentation of determinants needed for the entry of Salmonella species into mammalian cells.<BOP> | P0A1K8 |
Q3JNY2 | PHNC_BURP1 | Phosphonates import ATP-binding protein PhnC | pseudomallei group | <M><D><A><I><R><I><E><R><L><S><K><T><F><P><N><G><R><K><G><L><E><D><I><D><L><A><I><A><P><G><E><M><V><A><L><I><G><A><S><G><S><G><K><S><T><L><L><R><Q><I><A><S><F><S><S><S><D><A><R><P><S><R><I><D><I><F><G><R><S><I><Q><R><D><G><R><I><A><R><D><V><R><R><M><R><R><D><I><G><F><V><F><Q><Q><F><N><L><V><D><R><L><S><V><E><T><N><V><L... | Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system.<BOP> | Q3JNY2 |
A4SRD4 | LEPA_AERS4 | Ribosomal back-translocase LepA | Aeromonas | <M><K><H><I><R><N><F><S><I><I><A><H><I><D><H><G><K><S><T><L><S><D><R><L><I><Q><T><C><G><G><L><S><S><R><E><M><Q><A><Q><V><L><D><S><M><D><L><E><R><E><R><G><I><T><I><K><A><Q><S><V><T><L><N><Y><Q><A><Q><D><G><N><T><Y><Q><L><N><F><I><D><T><P><G><H><V><D><F><S><Y><E><V><S><R><S><L><A><A><C><E><G><A><L><L><V><V><D><A><G><Q><G... | Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre-t... | A4SRD4 |
Q0IBC2 | RECR_SYNS3 | Recombination protein RecR | unclassified Synechococcus | <M><I><D><Q><F><E><R><L><P><G><I><G><P><R><T><A><Q><R><L><A><L><H><L><L><R><Q><P><E><E><Q><I><H><S><F><A><D><A><L><L><A><A><R><S><Q><V><G><Q><C><Q><T><C><F><H><L><S><A><E><P><T><C><E><I><C><R><N><P><E><R><S><I><G><M><L><C><V><V><A><D><S><R><D><L><L><A><L><E><R><T><R><E><Y><A><G><R><Y><H><V><L><G><G><L><I><S><P><M><D><G... | May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO.<BOP> | Q0IBC2 |
Q884I3 | LOLD_PSESM | Lipoprotein-releasing system ATP-binding protein LolD | Pseudomonas | <M><S><D><K><A><V><L><S><C><R><N><L><G><K><S><Y><E><E><G><P><E><S><V><V><V><L><S><G><L><Q><L><E><L><H><P><G><E><R><V><A><I><V><G><T><S><G><S><G><K><S><T><L><L><N><L><L><G><G><L><D><T><P><S><E><G><S><V><W><L><A><G><E><E><L><S><A><L><G><E><K><A><R><G><L><L><R><N><R><A><L><G><F><V><Y><Q><F><H><H><L><L><P><E><F><T><A><L><E... | Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner.<BOP> | Q884I3 |
A9B9C4 | PSBX_PROM4 | Photosystem II reaction center X protein | Prochlorococcus | <M><A><F><P><V><L><N><L><L><L><D><V><A><V><S><S><E><A><A><T><N><S><A><I><G><M><I><G><S><F><L><A><A><A><A><F><I><V><V><P><A><A><S><F><L><I><W><V><S><Q><K><D><A><L><E><R><K><R> | Involved in the binding and/or turnover of quinones at the Q(B) site of Photosystem II.<BOP> | A9B9C4 |
P58097 | HSLO_CAUVC | Heat shock protein 33 homolog | Caulobacter | <M><T><D><I><A><P><D><T><G><V><L><D><D><V><V><S><A><F><Q><I><E><N><L><P><V><R><G><R><V><V><R><L><G><A><A><I><D><E><V><L><T><R><H><D><Y><P><E><P><V><A><N><L><L><G><E><A><C><A><L><A><A><L><V><G><S><S><L><K><F><E><G><R><L><I><V><Q><A><Q><G><D><G><P><V><R><Y><V><V><V><D><Y><D><T><S><G><G><L><R><G><Y><C><R><F><D><P><E><E><V... | Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress.<BOP> | P58097 |
B6JLX1 | DDL_HELP2 | D-alanylalanine synthetase | Helicobacter | <M><E><F><C><V><L><F><G><G><A><S><F><E><H><E><I><S><I><V><S><A><I><A><L><K><E><V><L><K><D><R><I><K><H><F><I><F><L><D><E><N><H><H><F><Y><L><I><E><A><S><N><M><H><S><K><Y><F><A><Q><I><K><E><K><K><L><P><P><L><I><L><A><H><N><G><L><L><K><N><S><F><L><G><T><K><I><I><E><L><P><L><V><I><N><L><V><H><G><G><D><G><E><D><G><K><L><A><S... | Cell wall formation.<BOP> | B6JLX1 |
Q7NK82 | GPMA1_GLOVI | 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase 1 | Gloeobacter | <M><A><H><L><I><L><I><R><H><G><Q><S><L><W><N><A><A><N><K><F><T><G><W><V><D><V><P><L><S><E><R><G><R><A><E><A><T><I><A><S><C><K><L><R><D><Y><R><V><N><V><C><F><T><S><M><L><M><R><A><I><E><T><A><V><I><T><L><T><E><C><D><D><I><C><G><G><K><I><P><I><I><K><H><E><A><D><D><E><N><W><H><G><W><D><N><Y><D><G><D><P><A><A><E><L><P><I><Y... | Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.<BOP> | Q7NK82 |
A2ALI5 | AJAP1_MOUSE | Adherens junction-associated protein 1 | Mus | <M><W><I><Q><Q><L><L><G><L><S><S><M><S><I><R><W><P><G><R><S><L><G><S><H><A><W><I><L><I><A><M><L><Q><L><A><V><D><F><P><S><C><D><S><L><G><P><G><P><E><F><R><L><L><S><R><P><Q><R><P><Q><R><L><W><S><L><R><S><G><P><P><T><R><L><P><T><P><A><W><S><P><R><A><A><R><A><E><R><A><H><G><P><I><Q><M><Q><T><P><R><A><R><R><A><H><R><P><R><D... | Plays a role in cell adhesion and cell migration.<BOP> | A2ALI5 |
Q2J6V2 | ILVC_FRACC | Ketol-acid reductoisomerase type I | Frankia | <M><V><E><I><Y><Y><D><D><D><A><S><L><D><V><L><A><D><R><K><V><A><V><I><G><Y><G><S><Q><G><H><A><H><A><L><N><L><R><D><S><G><V><D><V><R><V><G><L><P><A><D><S><R><S><R><A><R><A><E><E><E><G><L><R><V><L><T><P><A><E><A><S><A><E><A><D><I><I><M><L><L><T><P><D><T><T><H><R><T><I><Y><A><E><S><I><A><P><H><L><T><A><G><K><A><L><A><F><G... | Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobu... | Q2J6V2 |
P51580 | TPMT_HUMAN | Thiopurine methyltransferase | Homo | <M><D><G><T><R><T><S><L><D><I><E><E><Y><S><D><T><E><V><Q><K><N><Q><V><L><T><L><E><E><W><Q><D><K><W><V><N><G><K><T><A><F><H><Q><E><Q><G><H><Q><L><L><K><K><H><L><D><T><F><L><K><G><K><S><G><L><R><V><F><F><P><L><C><G><K><A><V><E><M><K><W><F><A><D><R><G><H><S><V><V><G><V><E><I><S><E><L><G><I><Q><E><F><F><T><E><Q><N><L><S><Y... | Catalyzes the S-methylation of thiopurine drugs such as 6-mercaptopurine (also called mercaptopurine, 6-MP or its brand name Purinethol) and 6-thioguanine (also called tioguanine or 6-TG) using S-adenosyl-L-methionine as the methyl donor . TPMT activity modulates the cytotoxic effects of thiopurine prodrugs. A natural ... | P51580 |
A3CVT7 | THIC_METMJ | Thiamine biosynthesis protein ThiC | Methanoculleus | <M><S><L><I><E><D><A><R><R><G><V><V><T><E><E><M><R><I><V><A><A><A><E><G><V><T><E><D><F><V><R><R><G><V><A><E><G><H><I><V><I><P><V><S><P><Y><R><R><V><K><I><C><G><I><G><E><G><L><R><T><K><V><N><A><S><I><G><T><S><T><D><M><V><D><V><D><M><E><V><E><K><V><R><Q><A><E><R><A><G><A><D><T><L><M><E><L><S><T><G><G><D><F><L><E><I><R><R... | Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.<BOP> | A3CVT7 |
Q98DG5 | MSCL2_RHILO | Large-conductance mechanosensitive channel 2 | Mesorhizobium | <M><L><K><E><F><Q><E><F><I><S><K><G><N><V><M><D><L><A><V><G><V><I><I><G><A><A><F><G><K><I><V><D><S><L><V><N><D><I><I><M><P><V><I><G><A><I><F><G><G><L><D><F><N><N><Y><F><V><G><L><S><S><A><V><N><A><T><S><L><A><D><A><K><K><Q><G><A><V><F><A><Y><G><S><F><I><T><V><A><L><N><F><V><I><L><A><F><I><I><F><L><M><V><K><A><V><N><N><L... | Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell.<BOP> | Q98DG5 |
Q6EW15 | RK14_NYMAL | 50S ribosomal protein L14, chloroplastic | Nymphaea | <M><I><Q><P><Q><T><L><L><N><V><A><D><N><S><G><A><R><K><L><M><C><I><R><I><I><G><A><S><N><Y><R><Y><A><H><I><G><D><V><I><V><A><V><I><K><E><A><V><P><N><M><P><L><E><R><S><E><V><I><R><A><V><I><V><R><T><C><K><E><L><K><R><D><N><G><M><I><I><R><Y><D><D><N><A><A><V><V><I><D><Q><E><G><N><P><K><G><T><R><V><F><G><S><I><A><R><E><L><R... | Binds to 23S rRNA.<BOP> | Q6EW15 |
B0R7F9 | CAPPA_HALS3 | Phosphoenolpyruvate carboxylase | Halobacterium | <M><V><D><V><P><R><L><M><S><T><Q><H><P><D><N><A><T><L><P><F><F><T><A><G><D><V><I><E><G><E><D><E><I><Q><E><A><Y><Y><V><Y><S><H><L><G><C><D><E><Q><M><W><D><F><E><G><K><E><G><D><E><Y><A><V><K><K><L><L><S><R><Y><D><E><F><F><A><D><H><Q><L><G><T><D><V><R><L><T><V><R><G><P><N><P><D><V><E><G><S><E><A><K><I><L><L><E><I><L><E><S... | Catalyzes the irreversible beta-carboxylation of phosphoenolpyruvate (PEP) to form oxaloacetate (OAA), a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle.<BOP> | B0R7F9 |
A4FUD4 | PEX12_BOVIN | Peroxin-12 | Bos | <M><A><E><H><G><A><H><I><T><T><A><S><V><V><D><D><Q><P><S><I><F><E><V><V><A><Q><D><S><L><M><S><A><V><R><P><A><L><Q><H><V><V><K><V><L><A><E><S><N><P><A><H><F><G><F><F><W><R><W><F><D><E><I><F><T><L><L><D><L><L><L><Q><Q><H><Y><L><S><K><T><S><A><S><F><S><E><N><F><Y><G><L><K><R><I><V><M><G><D><Q><H><K><L><Q><R><L><A><N><A><G... | Required for protein import into peroxisomes.<BOP> | A4FUD4 |
A4YCM2 | YIDC_SHEPC | Membrane protein YidC | Shewanella | <M><E><S><Q><R><N><I><L><L><I><G><L><L><F><V><S><F><L><L><W><Q><Q><W><Q><A><D><K><A><P><K><P><V><A><T><E><S><S><L><V><A><N><V><A><S><T><H><S><A><D><V><P><E><A><D><T><G><V><P><A><A><V><A><A><S><K><N><L><I><T><V><K><T><D><Q><L><D><V><Q><I><N><P><V><G><G><D><I><V><F><A><A><L><V><S><H><K><M><E><Q><G><K><E><Q><P><F><V><L><L... | Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning memb... | A4YCM2 |
C6DF52 | LOLA_PECCP | Outer-membrane lipoprotein carrier protein | Pectobacterium | <M><K><K><W><L><A><I><S><C><L><I><A><G><M><T><S><T><A><V><Y><A><D><A><A><K><D><L><Q><G><R><L><N><K><V><N><S><F><H><A><N><F><S><Q><K><V><T><S><A><D><G><A><A><V><Q><E><G><E><G><E><L><W><L><K><R><P><N><L><F><N><W><K><T><T><S><P><D><E><S><T><L><I><S><D><G><K><T><L><W><F><Y><N><P><F><V><E><Q><V><T><A><T><W><L><K><D><A><T><G... | Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane).<BOP> | C6DF52 |
Q9WV23 | CMAH_CRIGR | CMP-NeuAc hydroxylase | Cricetulus | <K><Q><T><A><E><T><L><L><S><L><S><P><A><E><T><A><N><L><K><E><G><I><N><F><F><R><N><K><T><T><G><K><E><Y><I><L><Y><K><E><K><N><H><L><K><A><C><K><N><L><C><K><H><Q><G><G><L><F><I><K><D><I><E><D><L><D><G><R><S><V><K><C><T><K><H><N><W><K><L><D><V><S><T><M><K><Y><I><N><P><P><G><S><F><C><Q><D><E><L><V><V><E><M><D><G><N><D><G><L... | Sialic acids are components of carbohydrate chains of glycoconjugates and are involved in cell-cell recognition and cell-pathogen interactions. Catalyzes the conversion of CMP-N-acetylneuraminic acid (CMP-Neu5Ac) into its hydroxylated derivative CMP-N-glycolylneuraminic acid (CMP-Neu5Gc), a sialic acid abundantly expre... | Q9WV23 |
A1T876 | PDXT_MYCVP | Pyridoxal 5'-phosphate synthase glutaminase subunit | Mycolicibacterium | <M><S><A><P><Q><V><G><V><L><A><L><Q><G><D><T><R><E><H><L><A><A><L><R><E><A><G><A><E><A><R><T><V><R><R><L><D><E><L><N><S><V><D><A><L><V><I><P><G><G><E><S><T><A><M><S><H><L><L><R><E><F><G><L><L><E><P><L><R><A><R><L><A><E><G><M><P><A><Y><G><S><C><A><G><M><I><L><L><A><T><E><I><A><D><A><G><V><A><G><R><E><A><L><P><L><G><G><I... | Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS.<BOP> | A1T876 |
Q2YAA5 | NUOA_NITMU | NUO1 | Nitrosospira | <M><N><A><S><A><T><Q><A><T><E><I><W><P><L><V><A><Y><F><F><L><V><V><M><L><V><V><G><V><M><A><L><S><Y><I><I><G><E><R><H><R><S><K><A><T><D><E><P><F><E><S><G><I><V><T><V><G><L><A><R><F><R><L><S><A><K><F><Y><L><I><A><V><F><F><V><I><F><D><V><E><A><V><F><L><F><A><W><A><V><A><F><R><E><L><G><W><P><G><Y><I><E><A><I><I><F><I><S><I... | NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are t... | Q2YAA5 |
C4LC60 | RNH_TOLAT | Ribonuclease H | Tolumonas | <M><L><K><Q><I><T><L><Y><T><D><G><S><C><L><G><N><P><G><P><G><G><Y><A><A><V><L><I><Y><K><Q><H><R><K><E><L><A><Q><G><Y><E><L><T><T><N><N><R><M><E><L><M><A><A><I><A><G><L><Q><S><L><S><E><P><C><Q><V><R><L><T><T><D><S><Q><Y><V><R><Q><G><I><T><Q><W><I><H><G><W><K><K><K><G><W><K><T><A><N><R><E><P><V><K><N><V><D><L><W><L><L><L... | Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.<BOP> | C4LC60 |
Q7V2K6 | TSAD_PROMP | tRNA threonylcarbamoyladenosine biosynthesis protein TsaD | Prochlorococcus | <M><H><K><V><L><A><I><E><T><S><C><D><E><T><S><V><S><I><V><S><N><S><G><D><I><Y><K><I><H><S><N><I><V><A><S><Q><I><E><D><H><S><K><W><G><G><V><V><P><E><L><A><A><R><K><H><L><E><L><L><P><F><V><L><E><Q><A><L><E><E><S><K><I><R><I><E><K><I><D><V><I><A><S><T><V><T><P><G><L><V><G><C><L><R><V><G><S><I><T><A><R><S><L><C><T><L><Y><S... | Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct ca... | Q7V2K6 |
A9BZY6 | DAPE_DELAS | N-succinyl-LL-2,6-diaminoheptanedioate amidohydrolase | Delftia | <M><S><R><T><L><Q><L><T><E><Q><L><I><S><L><P><S><V><T><P><E><D><A><G><C><L><E><L><L><A><D><A><L><Q><P><M><G><F><A><C><E><R><I><D><S><G><P><D><S><F><R><V><R><N><L><W><A><R><R><S><G><T><G><A><D><R><P><V><L><V><F><A><G><H><T><D><V><V><P><T><G><P><L><E><Q><W><S><S><P><P><F><V><P><T><H><R><D><G><K><L><Y><G><R><G><A><S><D><M... | Catalyzes the hydrolysis of N-succinyl-L,L-diaminopimelic acid (SDAP), forming succinate and LL-2,6-diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls.<BOP> | A9BZY6 |
Q4J8L2 | PDXT_SULAC | Pyridoxal 5'-phosphate synthase glutaminase subunit | Sulfolobus | <M><K><V><G><V><I><A><Y><Q><G><S><F><E><E><H><A><I><Q><L><K><R><A><M><S><K><L><N><L><T><G><E><V><I><A><V><K><K><P><K><D><V><D><L><I><D><G><V><V><I><P><G><G><E><S><T><T><I><G><I><I><A><E><K><L><G><V><L><D><E><I><K><A><K><I><N><A><G><L><P><V><L><G><T><C><A><G><A><I><M><L><A><K><D><V><S><D><A><K><V><G><K><K><S><Q><P><L><I... | Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS.<BOP> | Q4J8L2 |
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