accession
stringlengths
6
10
name
stringlengths
6
11
Full Name
stringlengths
1
147
taxon
stringlengths
3
46
sequence
stringlengths
48
2.3k
function
stringlengths
11
1.34k
AlphaFoldDB
stringlengths
6
10
P79875
TPG_RANTE
Temporin-G
Rana
<M><F><T><L><K><K><S><L><L><L><L><F><F><L><G><T><I><N><L><S><L><C><E><E><E><R><D><A><D><E><E><R><R><D><D><L><E><E><R><D><V><E><V><E><K><R><F><F><P><V><I><G><R><I><L><N><G><I><L><G><K>
Amphipathic alpha-helical antimicrobial peptide with activity against Gram-positive bacteria (M.luteus), Gram-negative bacteria (E.coli), and fungi (S.cerevisiae) . Stimulates insulin release from pancreatic beta-cells in a dose-dependent manner, without increasing intracellular calcium . Does not protects BRIN-BD11 be...
P79875
B5FP62
BIOF_SALDC
8-amino-7-ketopelargonate synthase
Salmonella
<M><S><W><Q><Q><R><V><D><D><A><L><T><A><R><R><A><T><D><T><L><R><R><R><Y><V><V><S><Q><G><A><G><R><W><L><V><A><N><G><R><Q><Y><L><N><F><S><S><N><D><Y><L><G><L><S><Q><H><P><Q><I><I><R><A><W><Q><Q><A><A><T><R><F><G><V><G><S><G><G><S><G><H><I><S><G><Y><S><V><A><H><Q><A><L><E><E><E><L><A><Q><W><L><G><Y><P><R><A><L><L><F><I><S...
Catalyzes the decarboxylative condensation of pimeloyl-[acyl-carrier protein] and L-alanine to produce 8-amino-7-oxononanoate (AON), [acyl-carrier protein], and carbon dioxide.<BOP>
B5FP62
Q72L31
DCUP_THET2
Uroporphyrinogen decarboxylase
Thermus
<M><D><L><V><N><D><L><I><L><R><A><A><R><G><E><P><T><P><R><P><P><V><W><F><M><R><Q><A><G><R><Y><Q><K><A><Y><R><K><L><R><E><R><Y><T><L><P><E><I><V><Q><N><P><E><V><C><A><E><V><T><L><L><P><V><K><A><L><G><V><D><A><A><I><L><F><A><D><I><T><T><P><L><Y><G><M><G><V><D><L><S><L><V><E><N><K><G><P><V><I><H><N><P><V><R><D><E><K><G><V...
Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.<BOP>
Q72L31
C3PP47
RL25_RICAE
General stress protein CTC
spotted fever group
<M><S><E><I><L><E><L><E><A><E><S><R><T><E><F><G><T><G><A><A><R><A><L><R><R><A><G><R><V><P><A><I><I><Y><G><A><G><K><T><P><V><S><I><S><L><E><E><K><E><I><T><K><Y><Y><R><K><P><A><F><I><S><Q><L><I><N><L><T><I><D><K><K><K><Y><K><V><L><P><K><A><V><E><L><H><P><V><T><D><I><V><R><H><V><D><F><V><F><L><E><E><K><T><Q><K><M><E><V><P...
This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance.<BOP>
C3PP47
Q9S4Z0
METN_SALEN
Methionine import ATP-binding protein MetN
Salmonella
<M><I><E><I><E><K><V><C><V><D><F><T><A><G><R><G><T><S><G><A><G><K><S><T><L><L><R><T><L><N><A><L><T><R><P><S><Q><G><R><V><N><V><N><G><V><E><I><S><A><L><D><G><K><A><L><R><Q><A><R><Q><R><I><G><M><I><F><Q><H><F><N><L><M><H><T><R><T><V><A><Q><N><V><A><F><S><L><K><A><A><G><W><E><R><S><K><I><A><P><R><V><A><E><I><L><T><L><V><G...
Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system.<BOP>
Q9S4Z0
Q15Q18
MURC_PSEA6
UDP-N-acetylmuramoyl-L-alanine synthetase
Pseudoalteromonas
<M><I><A><P><D><K><V><H><Y><H><V><P><E><M><R><R><I><K><N><I><H><F><V><G><I><G><G><A><G><M><G><G><I><A><E><V><L><L><N><E><G><Y><Q><V><S><G><S><D><R><Q><A><N><G><M><T><D><R><L><S><G><L><G><A><T><I><F><F><G><H><Q><A><S><N><V><E><K><A><N><V><V><V><V><S><S><A><I><D><P><T><N><P><E><V><N><A><A><N><E><M><R><I><P><V><I><R><R><A...
Cell wall formation.<BOP>
Q15Q18
Q9MLJ8
CYB_BUNFA
Ubiquinol-cytochrome-c reductase complex cytochrome b subunit
Bungarus
<M><S><N><Q><H><I><L><L><M><S><N><L><L><P><V><G><S><N><I><S><T><W><W><N><F><G><S><M><L><L><T><C><L><L><L><Q><I><M><T><G><F><F><L><A><I><H><Y><T><A><N><I><N><L><A><F><S><S><V><V><H><I><L><R><D><V><P><Y><G><W><I><M><Q><N><I><H><A><I><G><A><S><L><F><F><I><C><I><Y><I><H><I><A><R><G><L><Y><Y><G><L><Y><L><N><K><E><V><W><L><S...
Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain. The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c. Contributes to the generation of a proton gradient across the mitochondrial membrane that is...
Q9MLJ8
Q0V869
OTU11_ARATH
Deubiquitinating enzyme OTU11
Arabidopsis
<M><D><E><N><H><R><N><P><F><A><N><A><S><T><S><A><R><A><S><G><S><T><S><A><S><S><N><S><S><F><S><S><S><V><A><D><T><D><D><D><Q><T><I><A><R><I><L><A><E><D><E><S><L><R><R><E><G><K><L><G><K><R><L><S><H><L><D><S><I><P><H><T><P><R><V><N><R><E><I><P><D><I><N><D><A><T><L><D><H><E><L><L><S><G><R><L><A><T><Y><G><L><A><E><L><Q><M><E...
Hydrolase that can remove conjugated ubiquitin from proteins in vitro and may therefore play an important regulatory role at the level of protein turnover by preventing degradation (Probable). Inactive cysteine protease .<BOP>
Q0V869
Q986D2
ATPF1_RHILO
F-type ATPase subunit b 1
Mesorhizobium
<M><F><V><T><S><A><F><A><E><E><T><A><P><A><V><T><G><G><D><T><H><S><G><T><G><V><P><A><E><A><H><G><T><F><P><P><F><D><P><A><T><F><P><S><Q><L><L><W><L><A><I><T><F><G><L><F><Y><L><F><L><K><K><V><A><M><P><R><I><G><G><I><I><D><V><R><N><D><R><I><S><Q><D><L><D><Q><A><S><K><L><K><G><E><A><D><A><A><V><A><A><Y><E><Q><E><L><A><E><A...
Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0).<BOP>
Q986D2
Q9BEG8
S26A2_BOVIN
Solute carrier family 26 member 2
Bos
<M><S><L><K><N><E><D><Q><N><D><L><S><P><K><D><S><V><K><G><N><D><Q><Y><R><A><P><S><G><I><H><L><E><P><E><E><E><S><R><N><D><F><W><Q><F><E><P><S><N><L><F><R><H><P><R><I><H><L><E><P><Q><E><K><S><D><N><N><F><K><K><F><V><I><K><K><L><E><K><S><C><Q><C><S><S><T><K><A><K><N><T><I><F><G><F><L><P><V><L><Q><W><L><P><K><Y><D><L><K><K...
Sulfate transporter. May play a role in endochondral bone formation.<BOP>
Q9BEG8
Q7U669
PSBA2_PARMW
Photosystem II Q(B) protein 2
Parasynechococcus marenigrum
<M><S><T><A><I><R><S><G><R><Q><S><N><W><E><A><F><C><Q><W><V><T><D><T><N><N><R><I><Y><V><G><W><F><G><V><L><M><I><P><C><L><L><A><A><T><I><C><F><T><I><A><F><I><A><A><P><P><V><D><I><D><G><I><R><E><P><V><A><G><S><L><I><Y><G><N><N><I><I><S><G><A><V><V><P><S><S><N><A><I><G><L><H><F><Y><P><I><W><E><A><A><S><L><D><E><W><L><Y><N...
Photosystem II (PSII) is a light-driven water:plastoquinone oxidoreductase that uses light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation. It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photoni...
Q7U669
C1EYK0
KDPB_BACC3
Potassium-translocating ATPase B chain
Bacillus cereus group
<M><M><R><P><I><V><V><K><E><K><Q><I><H><V><V><E><D><E><V><R><Q><A><K><T><M><D><R><D><I><V><K><H><A><M><K><Q><S><F><A><K><L><N><P><K><V><M><I><K><N><P><I><M><F><V><V><E><I><G><F><I><I><T><F><I><L><S><F><L><P><S><H><S><S><S><V><P><G><W><F><N><I><T><V><S><L><I><L><L><F><T><V><L><F><A><N><F><A><E><A><L><A><E><G><R><G><K><A...
Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system and for the release of the potassium ions to the cytoplasm.<BOP...
C1EYK0
P44679
YBGC_HAEIN
Acyl-CoA thioesterase YbgC
Haemophilus
<M><L><D><N><G><F><S><F><P><V><R><V><Y><Y><E><D><T><D><A><G><G><V><V><Y><H><A><R><Y><L><H><F><F><E><R><A><R><T><E><Y><L><R><T><L><N><F><T><Q><Q><T><L><L><E><E><Q><Q><L><A><F><V><V><K><T><L><A><I><D><Y><C><V><A><A><K><L><D><D><L><L><M><V><E><T><E><V><S><E><V><K><G><A><T><I><L><F><E><Q><R><L><M><R><N><T><L><M><L><S><K><A...
Displays acyl-CoA thioesterase activity with short chain aliphatic acyl-CoA thioesters, such as propionyl-CoA and butyryl-CoA. Enzyme activity is relatively low, suggesting that the acyl-CoA thioesters used in the assays are not the physiological substrates. Has no detectable activity with 4-hydroxybenzoyl-CoA, lauroyl...
P44679
A0A3B7TLV2
BLN06_BRELC
RxLR effector protein BLN06
Bremia
<M><T><L><L><H><C><W><L><L><L><V><G><H><L><A><S><T><A><Y><A><D><F><I><T><K><D><F><K><S><L><P><P><P><A><Y><D><T><N><A><T><Q><A><L><V><P><Y><N><A><A><L><E><E><R><N><G><P><S><S><S><T><A><L><L><Q><Y><I><D><H><K><P><G><L><M><K><K><L><L><A><G><L><S><I><R><F><A><P><P><T><M><K><V><I><S><T><P><T><D><M><L><R><I><D><K><I><K><N><N...
Secreted effector that triggers a robust hypersensitive response (HR) in Lactuca serriola LS102. The response to BLN06 was visible as chlorosis but not as strong necrosis.<BOP>
A0A3B7TLV2
B7NL82
MDTG_ECO7I
Multidrug resistance protein MdtG
Escherichia
<M><S><P><C><E><N><D><P><P><I><N><W><K><R><N><L><I><V><A><W><L><G><C><F><L><T><G><A><A><F><S><L><V><M><P><F><L><P><L><Y><V><E><Q><L><G><V><T><G><H><S><A><L><N><M><W><S><G><I><V><F><S><I><T><F><L><F><S><A><I><A><S><P><F><W><G><G><L><A><D><R><K><G><R><K><L><M><L><L><R><S><A><L><G><M><G><I><V><M><V><L><M><G><L><A><Q><N><I...
Confers resistance to fosfomycin and deoxycholate.<BOP>
B7NL82
B0SFT5
NUOB_LEPBA
NDH-1 subunit B
Leptospira
<M><G><L><T><E><T><L><S><K><P><G><E><M><F><G><D><M><F><Q><V><A><T><L><D><N><V><V><Q><W><G><Q><S><F><S><L><W><P><Y><P><F><A><T><A><C><C><G><I><E><Y><M><S><T><A><C><A><D><Y><D><I><A><R><F><G><A><E><R><P><S><F><S><P><R><Q><A><D><M><I><L><V><L><G><T><I><T><Y><K><M><A><P><V><L><R><Q><I><Y><D><Q><L><A><E><P><K><F><V><I><S><V...
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are t...
B0SFT5
A0B6D7
RFCL_METTP
Clamp loader large subunit
Methanothrix
<M><T><S><W><A><E><K><Y><R><P><K><N><L><D><G><I><L><G><N><A><K><A><V><S><E><L><R><A><W><A><M><A><W><E><K><G><R><P><E><V><K><C><L><I><L><Y><G><P><P><G><V><G><K><T><S><A><A><L><A><L><A><S><E><M><D><W><D><Y><I><E><L><N><A><S><D><Q><R><T><A><E><I><I><K><S><I><A><G><P><A><S><Q><V><S><T><F><S><G><R><R><R><L><V><I><L><D><E><A...
Part of the RFC clamp loader complex which loads the PCNA sliding clamp onto DNA.<BOP>
A0B6D7
P47323
OPPB_MYCGE
Oligopeptide transport system permease protein OppB
Mycoplasma
<M><F><K><Y><I><L><K><R><L><G><L><A><V><V><A><M><F><I><V><M><S><I><V><F><F><L><V><N><A><T><G><N><V><P><L><S><A><T><S><A><R><D><I><A><A><V><Q><A><Q><L><Q><E><F><G><F><N><D><P><I><I><V><R><Y><F><R><Y><W><A><K><L><F><S><F><Q><A><D><A><L><G><I><Y><Y><A><N><P><N><Q><T><I><G><E><I><V><F><A><R><V><P><N><T><L><Y><V><V><L><I><S...
Part of the binding-protein-dependent transport system for oligopeptides; probably responsible for the translocation of the substrate across the membrane.<BOP>
P47323
Q1GPB2
RS14_SPHAL
30S ribosomal protein S14
Sphingopyxis
<M><A><K><L><S><S><V><N><K><N><E><R><R><K><K><L><V><K><K><Y><A><G><R><Y><A><K><L><K><A><I><A><A><D><S><S><L><D><D><G><E><R><L><I><A><R><L><K><M><A><E><I><P><R><N><G><N><P><T><R><I><R><N><R><C><E><L><T><G><R><P><R><A><Y><Y><R><K><F><R><L><C><R><V><Q><L><R><D><L><A><N><K><G><L><I><P><G><V><V><K><S><S><W>
Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.<BOP>
Q1GPB2
Q7V479
RL11_PROMM
50S ribosomal protein L11
Prochlorococcus
<M><A><K><K><V><V><S><V><I><K><L><A><L><Q><A><G><K><A><N><P><A><P><P><V><G><P><A><L><G><Q><H><G><V><N><I><M><A><F><C><K><E><Y><N><A><R><T><Q><D><K><A><G><L><V><I><P><V><E><I><S><V><F><E><D><R><S><F><T><F><I><T><K><T><P><P><A><S><V><L><I><T><K><A><A><G><I><E><K><G><S><G><E><S><A><H><G><K><V><G><S><L><S><R><S><Q><L><E><E...
Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.<BOP>
Q7V479
Q7V8E7
MEND_PROMM
2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthase
Prochlorococcus
<M><G><L><R><H><L><V><L><C><P><G><S><R><S><G><P><L><A><L><A><A><G><G><M><A><R><T><N><R><L><R><L><S><T><A><I><D><E><R><S><A><A><F><L><A><L><G><F><S><T><A><T><G><T><A><A><A><V><V><T><T><S><G><T><A><V><A><N><L><L><P><A><A><V><E><A><D><R><S><C><Q><P><L><L><L><L><T><A><D><R><P><Y><R><L><K><D><C><G><A><N><Q><T><V><N><Q><E><T...
Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC).<BOP>
Q7V8E7
Q82DQ9
RL11_STRAW
50S ribosomal protein L11
Streptomyces
<M><P><P><K><K><K><K><V><T><G><L><I><K><L><Q><I><Q><A><G><A><A><N><P><A><P><P><V><G><P><A><L><G><Q><H><G><V><N><I><M><E><F><C><K><A><Y><N><A><A><T><E><S><Q><R><G><W><V><I><P><V><E><I><T><V><Y><E><D><R><S><F><T><F><I><T><K><T><P><P><A><A><K><M><I><L><K><A><A><G><V><E><K><G><S><G><E><P><H><K><T><K><V><A><K><I><T><Q><A><Q...
Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.<BOP>
Q82DQ9
A7STV9
SLX1_NEMVE
Structure-specific endonuclease subunit SLX1 homolog
Nematostella
<M><D><D><N><I><A><G><S><G><F><H><G><V><Y><L><L><Y><C><V><N><P><K><F><K><G><H><T><Y><I><G><Y><T><V><N><P><N><R><R><I><K><Q><H><N><G><G><V><D><K><G><G><A><Y><K><T><S><R><K><K><P><W><N><M><I><L><I><V><H><G><F><P><N><D><I><I><A><L><Q><F><E><W><A><W><Q><K><P><T><V><S><R><R><L><K><S><A><A><T><K><K><K><P><R><E><R><P><V><Q><Y...
Catalytic subunit of a heterodimeric structure-specific endonuclease that resolves DNA secondary structures generated during DNA repair and recombination. Has endonuclease activity towards branched DNA substrates, introducing single-strand cuts in duplex DNA close to junctions with ss-DNA.<BOP>
A7STV9
B9JC66
SSRP_AGRRK
Small protein B
Agrobacterium tumefaciens complex
<M><A><P><K><G><S><Q><R><V><V><K><K><I><V><A><E><N><R><K><A><R><F><N><Y><E><I><I><D><T><Y><E><A><G><I><V><L><M><G><T><E><V><K><S><L><R><E><G><K><A><N><I><A><E><S><Y><A><S><D><E><D><G><E><I><W><L><I><N><S><Y><L><P><E><Y><L><Q><A><N><R><F><N><H><E><P><R><R><R><R><K><L><L><L><S><G><R><E><I><G><R><L><R><S><G><I><N><R><E><G...
Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemb...
B9JC66
A5VS65
EFP_BRUO2
Elongation factor P
Brucella
<M><K><I><N><G><N><E><I><R><P><G><N><V><I><E><H><E><G><G><L><W><V><A><V><K><T><N><A><V><K><P><G><K><G><G><A><Y><N><Q><V><E><L><K><N><L><I><N><G><T><K><L><N><E><R><F><R><A><A><E><T><V><E><R><V><R><L><E><Q><K><D><F><S><F><L><Y><E><Q><G><E><A><L><I><F><M><D><T><E><T><Y><E><Q><L><E><L><Q><K><D><F><V><G><D><R><A><A><F><L><Q...
Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.<BOP>
A5VS65
A0KYB9
PLSX_SHESA
Phosphate-acyl-ACP acyltransferase
Shewanella
<M><T><S><L><T><L><A><L><D><A><M><G><G><D><H><G><P><H><V><T><V><P><A><A><L><R><A><L><K><S><H><S><S><L><K><I><I><L><V><G><D><K><T><E><I><D><V><Y><L><R><Q><A><E><Q><P><L><L><S><R><I><E><V><I><H><T><D><E><V><V><S><M><S><D><R><P><V><H><A><L><R><T><R><K><N><S><S><M><R><L><S><I><E><L><V><R><D><G><R><A><A><A><C><V><S><A><G><N...
Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA.<BOP>
A0KYB9
Q7MVY0
HCP_PORGI
Prismane protein
Porphyromonas
<M><E><K><K><M><F><C><Y><Q><C><Q><E><T><A><G><N><K><G><C><I><L><K><G><V><C><G><K><D><F><S><T><A><N><L><M><D><L><L><V><F><N><L><K><G><I><A><I><I><M><T><S><M><R><R><A><G><V><K><A><D><Y><R><K><A><D><K><A><I><M><E><S><L><F><A><T><I><T><N><A><N><F><D><Y><S><S><I><A><K><R><V><E><K><T><F><A><L><K><A><E><L><Y><S><L><A><F><T><Q...
Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O.<BOP>
Q7MVY0
Q4KD86
KATG_PSEF5
Peroxidase/catalase
Pseudomonas
<M><S><N><E><S><K><C><P><F><K><H><T><A><G><E><G><T><S><N><R><D><W><W><P><G><Q><L><N><L><K><I><L><H><Q><H><S><R><L><S><D><P><M><A><E><G><F><D><Y><A><A><E><F><K><T><L><D><L><A><A><V><K><R><D><L><Q><A><L><M><T><D><S><Q><P><W><W><P><A><D><F><G><H><Y><G><P><L><F><I><R><M><A><W><H><S><A><G><T><Y><R><I><A><D><G><R><G><G><A><G...
Bifunctional enzyme with both catalase and broad-spectrum peroxidase activity.<BOP>
Q4KD86
Q8CEK7
FATE1_MOUSE
Fetal and adult testis-expressed transcript protein homolog
Mus
<M><P><W><V><P><R><E><H><S><H><D><D><V><Q><L><Q><E><F><S><R><N><F><P><V><G><R><F><P><Y><E><C><L><E><A><D><I><M><A><K><I><G><L><E><E><L><N><G><L><E><M><E><V><M><R><R><Q><M><Q><M><T><S><G><R><L><H><I><L><E><D><Q><D><A><T><W><C><H><K><E><A><A><L><F><T><L><L><V><S><V><C><I><A><N><L><W><L><W><V><H><W>
Involved in the regulation of endoplasmic reticulum (ER)-mitochondria coupling. Negatively regulates the ER-mitochondria distance and Ca(2+) transfer from ER to mitochondria possibly implicating it in the regulation of apoptosis. May collaborate with RNF183 to restrain BIK protein levels thus regulating apoptotic signa...
Q8CEK7
P85966
AMP_TRIKH
Antimicrobial peptide 1a
Triticum
<M><K><P><H><M><S><A><T><V><L><R><A><P><R><V><A><A><I><L><L><A><V><V><L><A><A><V><L><A><T><A><V><N><G><A><Q><R><C><G><D><Q><A><R><G><A><K><C><P><N><C><L><C><C><G><K><Y><G><F><C><G><S><G><D><A><Y><C><G><A><G><S><C><Q><S><Q><C><R><G><C><R><D><D><V><V><G><Q><A><L><P><A><E><P><G><S><T><R><A><T><A><A><S><S><A><S><A><R><G><L...
Has antifungal activity against F.verticillioides (IC(50)=2.7 ug/ml). At concentrations between 45 uM and 225 uM, inhibits activity of metalloproteinase fungalysin Fv-cpm from F.verticillioides.<BOP>
P85966
A5F619
PYRH_VIBC3
Uridine monophosphate kinase
Vibrio
<M><T><T><N><P><K><P><A><Y><Q><R><I><L><L><K><L><S><G><E><A><L><Q><G><S><E><G><F><G><I><D><P><T><V><L><D><R><M><A><Q><E><V><K><E><L><V><E><L><G><V><Q><V><G><V><V><I><G><G><G><N><L><F><R><G><A><G><L><A><K><A><G><M><N><R><V><V><G><D><H><M><G><M><L><A><T><V><M><N><G><L><A><M><R><D><A><L><H><R><A><Y><V><N><A><R><L><M><S><A...
Catalyzes the reversible phosphorylation of UMP to UDP.<BOP>
A5F619
O15697
DRC4_TRYBR
T lymphocyte-triggering factor
Trypanosoma
<M><P><P><R><T><A><A><E><R><G><G><R><R><K><S><V><K><A><P><P><P><V><D><P><L><V><E><L><T><T><L><E><S><V><H><D><A><L><A><K><A><E><R><L><R><N><Y><F><Q><V><E><R><D><K><V><N><D><F><W><T><I><T><K><G><E><V><E><T><Y><R><N><R><L><F><N><A><E><A><S><I><E><E><L><E><R><S><H><Q><V><E><M><K><V><Y><K><Q><R><V><R><H><L><I><Y><E><R><K><K...
Cytoskeletal linker that plays a central role in the flagellum cell motility. Required for directional cell motility. Plays a role as part of a dynein regulatory system that regulates flagellar beat in response to signals from the central pair apparatus and radial spokes in procyclic cells. Also plays an essential role...
O15697
A7Z4W5
RECA_BACVZ
Recombinase A
Bacillus amyloliquefaciens group
<M><S><D><R><Q><A><A><L><D><M><A><L><K><Q><I><E><K><Q><F><G><K><G><S><I><M><K><L><G><E><K><T><D><T><R><I><S><T><V><P><S><G><S><L><A><L><D><T><A><L><G><I><G><G><Y><P><R><G><R><I><I><E><V><Y><G><P><E><S><S><G><K><T><T><V><A><L><H><A><I><A><E><V><Q><E><K><G><G><Q><A><A><F><I><D><A><E><H><A><L><D><P><V><Y><A><Q><K><L><G><V...
Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage.<BOP>
A7Z4W5
A7N6I9
CYOE2_VIBC1
Heme O synthase 2
Vibrio
<M><S><K><E><I><A><L><P><L><E><S><G><K><K><K><I><G><S><T><Y><L><K><L><T><K><P><K><V><V><A><L><M><L><I><T><A><V><V><G><M><S><L><A><P><V><V><D><F><P><W><L><Q><A><A><F><G><L><V><G><I><G><L><M><A><G><S><A><A><A><F><N><H><L><I><D><R><R><I><D><A><R><M><A><R><T><H><K><R><P><L><P><S><G><D><T><N><P><I><S><V><A><I><F><S><T><A><L...
Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group.<BOP>
A7N6I9
O35162
HSP13_RAT
Stress-70 protein chaperone microsome-associated 60 kDa protein
Rattus
<M><A><G><E><M><T><I><L><G><S><A><V><L><T><L><L><L><A><G><Y><L><A><Q><Q><Y><L><P><L><P><T><P><K><V><I><G><I><D><L><G><T><T><Y><C><S><V><G><V><F><F><P><G><T><G><K><V><K><V><I><P><D><E><N><G><H><I><S><I><P><S><M><V><S><F><T><D><G><D><V><Y><V><G><Y><E><S><L><E><L><A><D><S><N><P><Q><N><T><I><Y><D><A><K><R><F><I><G><K><I><F...
Has peptide-independent ATPase activity.<BOP>
O35162
P32335
MSS51_YEAST
Mitochondrial splicing suppressor protein 51
Saccharomyces
<M><T><V><L><Y><A><P><S><G><A><T><Q><L><Y><F><H><L><L><R><K><S><P><H><N><R><L><V><V><S><H><Q><T><R><R><H><L><M><G><F><V><R><N><A><L><G><L><D><P><P><P><S><P><E><D><P><T><P><E><N><R><F><H><P><W><D><Q><S><P><S><V><D><L><R><E><R><A><A><K><I><R><T><L><A><H><C><P><V><T><G><K><D><I><N><Y><T><C><P><L><S><G><I><P><T><H><H><S><R...
Has a dual role in the assembly of cytochrome oxidase subunit 1 (COX1). It has a regulative function on COX1 synthesis, acting as a translational activator specific for the COX1 mRNA, and it also binds to newly synthesized COX1 protein. Together with COX14, may act as a chaperone that binds efficiently unassembled COX1...
P32335
Q9I2N4
MODC_PSEAE
Molybdenum import ATP-binding protein ModC
Pseudomonas
<M><D><G><L><R><L><R><F><R><R><A><Y><P><G><F><E><L><D><I><D><L><A><L><P><G><R><G><V><T><A><L><F><G><H><S><G><S><G><K><S><T><C><L><R><C><I><A><G><L><E><K><A><A><E><G><E><V><T><I><N><G><E><T><W><Q><D><S><R><R><N><L><F><V><A><P><H><R><R><A><L><G><Y><V><F><Q><D><A><N><L><F><R><H><L><T><V><R><R><N><L><A><F><G><L><K><R><I><A...
Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system.<BOP>
Q9I2N4
B8GPP4
SYP_THISH
Prolyl-tRNA synthetase
Thioalkalivibrio
<M><R><A><T><R><F><P><L><A><T><L><K><E><T><P><A><D><A><E><V><I><S><H><Q><L><M><L><R><A><G><M><I><R><R><L><A><S><G><L><Y><S><W><T><P><L><G><L><R><V><L><R><K><V><E><G><L><V><R><D><E><M><D><R><A><G><A><L><E><L><L><M><P><A><V><Q><P><A><E><L><W><Q><E><S><G><R><W><E><Q><Y><G><P><E><L><L><R><L><K><D><R><H><M><R><E><F><C><F><G...
Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two addit...
B8GPP4
Q5ZSY2
KUP3_LEGPH
Probable potassium transport system protein kup 3
Legionella
<M><P><S><T><R><N><I><E><T><H><N><D><S><N><P><T><L><R><A><L><S><L><S><A><L><G><I><V><Y><G><D><I><G><T><S><P><L><Y><T><F><K><T><V><I><L><L><A><G><G><G><T><P><A><V><N><T><I><M><G><S><V><S><L><I><I><W><T><L><I><I><I><A><S><V><K><Y><I><H><F><A><L><R><I><D><N><D><G><E><G><G><I><L><A><L><M><S><L><L><S><L><K><L><K><Q><R><P><F...
Transport of potassium into the cell.<BOP>
Q5ZSY2
Q9RQ80
ATPG_BUCDN
F-ATPase gamma subunit
Buchnera
<M><A><S><I><K><E><I><K><T><Q><I><T><S><V><V><N><T><K><K><I><T><K><A><M><E><M><V><A><I><S><K><M><R><K><T><E><E><R><M><S><S><G><R><P><Y><S><E><I><I><R><K><V><I><N><H><V><A><Q><G><H><L><E><Y><K><H><S><Y><L><E><T><R><K><I><K><R><I><G><L><I><I><V><S><S><D><R><G><L><C><G><S><L><N><S><N><L><F><R><K><V><L><F><K><I><Q><N><F><T...
Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.<BOP>
Q9RQ80
A2QX23
ADAB_ASPNC
2-acetyl-2-decarboxamidoanthrotainin biosynthesis cluster protein B
Aspergillus subgen. Circumdati
<M><A><F><R><I><P><F><A><Q><S><F><W><Q><E><Y><L><S><G><Q><E><A><N><L><P><R><L><P><E><V><E><Q><V><T><E><T><V><M><R><I><L><G><G><N><P><G><R><M><Q><L><Q><G><T><N><T><Y><L><V><G><T><G><K><F><R><I><L><I><D><T><G><Q><G><E><A><S><W><I><E><A><L><T><K><Q><L><E><A><N><G><L><E><I><S><H><V><L><L><T><H><W><H><G><D><H><T><G><G><V><P...
Lactamase-like protein; part of the gene cluster that mediates the biosynthesis of the linear tetracyclic TAN-1612 neuropeptide Y receptor antagonist . The decaketide backbone of TAN-1612 is synthesized by the non-reducing polyketide synthase adaA via condensation of one acetyl-CoA starter unit with 9 malonyl-CoA units...
A2QX23
A5EP16
GFA_BRASB
S-(hydroxymethyl)glutathione synthase
unclassified Bradyrhizobium
<M><T><V><H><I><H><P><Y><V><D><N><G><V><K><Q><G><S><G><H><F><A><G><G><T><L><V><C><K><C><H><D><R><P><V><K><V><A><V><K><G><D><V><A><H><N><H><A><C><G><C><T><K><C><W><K><P><S><G><A><T><F><S><V><I><A><V><V><P><R><Q><N><V><T><V><L><E><N><G><D><K><L><K><I><V><D><P><S><A><V><I><Q><R><Y><A><C><T><G><C><G><T><H><M><Y><G><R><I><E...
Catalyzes the condensation of formaldehyde and glutathione to S-hydroxymethylglutathione.<BOP>
A5EP16
P18405
S5A1_HUMAN
Steroid 5-alpha-reductase 1
Homo
<M><A><T><A><T><G><V><A><E><E><R><L><L><A><A><L><A><Y><L><Q><C><A><V><G><C><A><V><F><A><R><N><R><Q><T><N><S><V><Y><G><R><H><A><L><P><S><H><R><L><R><V><P><A><R><A><A><W><V><V><Q><E><L><P><S><L><A><L><P><L><Y><Q><Y><A><S><E><S><A><P><R><L><R><S><A><P><N><C><I><L><L><A><M><F><L><V><H><Y><G><H><R><C><L><I><Y><P><F><L><M><R...
Converts testosterone into 5-alpha-dihydrotestosterone and progesterone or corticosterone into their corresponding 5-alpha-3-oxosteroids. It plays a central role in sexual differentiation and androgen physiology.<BOP>
P18405
Q04F85
RRF_OENOB
Ribosome-releasing factor
Oenococcus
<M><I><D><L><K><E><V><K><E><R><M><G><K><V><S><K><A><F><Q><N><E><L><I><N><I><R><A><G><R><A><N><P><N><I><L><N><K><I><Q><V><E><Y><Y><G><A><P><T><P><L><N><Q><L><A><S><V><Q><I><P><E><A><R><V><L><L><I><T><P><Y><D><K><T><S><L><K><A><I><E><Q><A><I><F><A><S><D><L><G><L><T><P><Q><N><D><G><S><A><I><R><L><I><I><P><Q><L><T><E><D><S...
Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another.<BOP>
Q04F85
Q6H500
RSBZ4_ORYSJ
bZIP transcription factor 15
Oryza sativa
<M><D><I><E><A><F><I><H><G><G><S><G><G><G><D><A><D><A><D><H><P><L><G><I><F><S><A><A><D><L><S><G><F><G><F><A><D><S><S><T><I><T><G><G><I><P><N><H><I><W><P><Q><S><Q><N><L><N><A><R><H><P><A><V><S><T><T><I><E><S><Q><S><S><I><C><A><A><A><S><P><T><S><A><T><N><L><N><M><K><E><S><Q><T><L><G><G><T><S><G><S><D><S><E><S><E><S><L><L...
Probable transcription factor that binds to the DNA specific sequence 5'-TGAGTCA-3' found in seed storage protein gene promoters.<BOP>
Q6H500
Q2S9Z8
LPXC_HAHCH
UDP-3-O-[R-3-hydroxymyristoyl]-N-acetylglucosamine deacetylase
Hahella
<M><I><K><Q><R><T><L><K><N><I><I><R><A><T><G><V><G><L><H><S><G><E><K><V><Y><L><T><L><K><P><A><P><V><D><T><G><V><V><F><C><R><T><D><L><D><P><I><V><E><I><P><A><R><A><E><N><V><G><E><T><L><L><S><T><T><L><V><K><S><G><V><K><I><A><T><V><E><H><L><L><S><A><L><A><G><L><G><I><D><N><C><Y><V><E><L><S><A><A><E><V><P><I><M><D><G><S><A...
Catalyzes the hydrolysis of UDP-3-O-myristoyl-N-acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis.<BOP>
Q2S9Z8
B9LA36
MSRA_NAUPA
Peptide-methionine (S)-S-oxide reductase
Nautilia
<M><P><K><A><V><F><G><G><G><C><F><W><C><L><D><A><V><F><R><K><V><D><G><V><R><D><V><V><V><G><Y><A><G><G><R><R><P><N><P><N><Y><E><Q><V><C><T><G><V><T><G><H><A><E><V><V><E><I><D><Y><D><E><N><T><V><S><Y><D><E><L><L><D><I><F><F><K><I><H><D><P><T><Q><L><N><R><Q><G><N><D><V><G><T><Q><Y><R><S><I><I><L><Y><L><D><E><E><Q><K><E><K...
Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.<BOP>
B9LA36
P59489
GREA_BUCBP
Transcript cleavage factor GreA
Buchnera
<M><N><D><Q><I><P><M><T><I><L><G><V><E><K><L><R><K><E><L><E><M><L><K><T><I><K><R><P><K><I><I><K><S><I><I><E><A><R><Q><H><G><D><L><K><E><N><S><E><Y><H><A><A><R><E><E><Q><G><F><C><E><G><R><I><K><E><I><E><L><K><L><S><K><A><R><I><I><D><I><T><K><V><K><N><N><G><V><I><I><F><G><S><T><V><T><I><L><N><L><T><S><N><Q><E><F><T><Y><R...
Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factor...
P59489
Q6LU34
CHEB1_PHOPR
Protein-glutamate methylesterase/protein-glutamine glutaminase 1
Photobacterium
<M><V><V><D><D><S><A><V><V><R><Q><V><V><S><S><V><L><K><S><D><S><E><I><E><V><C><G><A><V><A><D><P><L><F><A><M><T><R><M><R><M><Q><W><P><D><V><I><V><L><D><I><E><M><P><R><M><D><G><I><S><F><L><K><K><I><M><A><E><R><P><T><P><V><V><I><C><S><T><L><T><E><K><G><A><D><T><T><M><Q><A><I><S><A><G><A><V><E><I><I><T><K><P><K><V><G><L><K...
Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deam...
Q6LU34
B1KD01
AROE_SHEWM
Shikimate dehydrogenase (NADP(+))
Shewanella
<M><T><D><R><Y><A><V><F><G><N><P><I><S><H><S><K><S><P><L><I><H><G><I><F><A><N><E><T><Q><Q><V><L><D><Y><E><A><I><L><A><P><K><D><G><F><E><S><C><L><K><L><F><W><S><Q><N><G><K><G><A><N><V><T><A><P><F><K><E><Q><A><F><N><L><C><D><E><L><S><E><E><A><K><L><A><G><A><V><N><T><L><T><L><L><T><N><G><K><V><R><G><D><N><T><D><G><L><G><L...
Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).<BOP>
B1KD01
P75952
COMR_ECOLI
Copper outer membrane regulator
Escherichia
<M><A><T><D><S><T><Q><C><V><K><K><S><R><G><R><P><K><V><F><D><R><D><A><A><L><D><K><A><M><K><L><F><W><Q><H><G><Y><E><A><T><S><L><A><D><L><V><E><A><T><G><A><K><A><P><T><L><Y><A><E><F><T><N><K><E><G><L><F><R><A><V><L><D><R><Y><I><D><R><F><A><A><K><H><E><A><Q><L><F><C><E><E><K><S><V><E><S><A><L><A><D><Y><F><A><A><I><A><N><C...
Represses expression of BhsA/ComC by binding to its promoter region in the absence of copper.<BOP>
P75952
B1KRD4
SPEA_SHEWM
Biosynthetic arginine decarboxylase
Shewanella
<M><S><N><W><S><I><N><D><A><R><T><G><Y><N><V><N><Y><W><S><Q><G><L><Y><G><I><S><D><E><G><E><A><T><V><S><P><D><P><T><R><P><E><C><S><I><G><L><N><E><L><A><K><D><M><V><K><S><G><V><N><L><P><V><L><V><R><F><P><Q><I><L><H><H><R><V><N><S><L><C><Q><A><F><N><Q><A><I><Q><K><Y><Q><Y><Q><A><D><Y><L><L><V><Y><P><I><K><V><N><Q><Q><Q><T...
Catalyzes the biosynthesis of agmatine from arginine.<BOP>
B1KRD4
Q2KIY6
HORM1_BOVIN
HORMA domain-containing protein 1
Bos
<M><A><T><A><Q><L><Q><R><T><S><M><S><A><L><I><F><P><N><K><I><S><T><E><Q><Q><S><L><V><L><V><K><R><L><L><A><V><S><V><S><C><I><T><Y><L><R><G><I><F><P><E><C><A><Y><G><T><R><Y><L><D><D><L><C><V><K><I><L><R><E><D><K><N><C><P><G><S><T><Q><L><V><K><W><M><L><G><C><Y><D><A><L><H><K><K><Y><L><R><M><V><V><L><A><V><Y><T><N><P><E><D...
Plays a key role in meiotic progression. Regulates 3 different functions during meiosis: ensures that sufficient numbers of processed DNA double-strand breaks (DSBs) are available for successful homology search by increasing the steady-state numbers of single-stranded DSB ends. Promotes synaptonemal-complex formation i...
Q2KIY6
B5XUP9
RPPH_KLEP3
(Di)nucleoside polyphosphate hydrolase
Klebsiella
<M><I><D><D><D><G><Y><R><P><N><V><G><I><V><I><C><N><R><Q><G><Q><V><M><W><A><R><R><Y><G><Q><H><S><W><Q><F><P><Q><G><G><I><N><P><G><E><S><A><E><Q><A><M><Y><R><E><L><F><E><E><V><G><L><S><R><K><D><V><R><I><L><A><S><T><R><N><W><L><R><Y><K><L><P><K><R><L><V><R><W><D><T><K><P><V><C><I><G><Q><K><Q><K><W><F><L><L><Q><L><I><G><N...
Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage.<BOP>
B5XUP9
B2UU54
ACKA_HELPS
Acetokinase
Helicobacter
<M><E><I><L><V><L><N><L><G><S><S><S><I><K><F><K><L><F><D><M><K><E><N><K><P><L><A><S><G><L><A><E><K><I><G><E><E><I><G><Q><L><K><I><K><S><H><L><H><H><N><E><Q><E><L><K><E><K><L><V><I><K><D><H><A><S><G><L><L><M><I><R><E><N><L><T><K><M><G><I><I><K><D><F><N><Q><I><D><A><I><G><H><R><V><V><Q><G><G><D><K><F><H><A><P><I><L><V><N...
Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction.<BOP>
B2UU54
Q043X8
PRMA_LACGA
Ribosomal protein L11 methyltransferase
Lactobacillus
<M><K><L><L><A><V><K><V><E><C><S><H><E><L><E><D><G><L><S><F><F><M><Q><D><E><L><D><A><Q><G><I><E><S><R><K><R><S><D><F><V><A><E><G><Q><K><H><D><S><S><L><V><E><L><D><D><I><E><N><L><P><K><D><L><E><L><T><A><Y><F><N><Y><E><N><A><D><K><K><E><L><V><K><K><I><T><D><K><I><A><E><M><K><G><Y><G><L><N><T><G><E><V><S><I><S><T><K><E><V...
Methylates ribosomal protein L11.<BOP>
Q043X8
Q9D9S2
TM225_MOUSE
Transmembrane protein 225
Mus
<M><M><H><I><P><N><R><S><I><Q><A><A><N><I><F><F><S><S><G><A><I><L><L><L><I><V><G><L><I><M><E><D><W><V><E><L><I><P><K><V><R><K><D><K><T><T><H><S><P><W><L><G><C><C><P><P><F><W><P><E><E><S><L><E><V><V><R><R><I><M><R><M><T><L><N><I><S><I><Y><L><N><L><I><I><G><L><Q><F><S><Y><M><I><S><Q><N><K><C><V><H><L><L><V><G><F><L><S><F...
Probably inhibits protein phosphatase 1 (PP1) in sperm via binding to catalytic subunit PPP1CC.<BOP>
Q9D9S2
Q8RA55
RECA_CALS4
Recombinase A
Caldanaerobacter
<M><M><I><E><K><Q><K><A><L><E><M><A><I><S><Q><I><E><R><Q><F><G><K><G><A><I><M><R><L><G><D><T><A><K><L><N><V><E><V><I><P><T><G><S><L><E><L><D><I><A><L><G><V><G><G><V><P><R><G><R><I><I><E><I><F><G><P><E><S><S><G><K><T><T><L><A><L><H><M><I><A><E><A><Q><K><I><G><G><T><G><A><F><I><D><A><E><H><A><L><D><P><V><Y><A><K><N><L><G...
Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage.<BOP>
Q8RA55
A5UFJ9
LIPB_HAEIG
Octanoyl-[acyl-carrier-protein]-protein N-octanoyltransferase
Haemophilus
<M><N><N><S><L><I><V><R><Q><L><G><L><Q><D><Y><Q><E><I><W><H><K><M><Q><D><F><T><D><T><R><N><A><E><T><Q><D><E><I><W><L><V><Q><H><Y><P><V><F><T><Q><G><Q><A><G><K><P><E><H><L><L><Q><R><S><E><I><P><V><V><Q><S><D><R><G><G><Q><I><T><Y><H><A><P><G><Q><Q><V><M><Y><V><L><I><D><I><K><R><H><K><N><L><N><V><R><Q><L><V><T><A><L><E><Q...
Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate.<BOP>
A5UFJ9
A3CSU7
CBID_METMJ
Cobalt-precorrin-6A synthase
Methanoculleus
<M><R><D><P><V><T><D><F><E><Y><P><A><A><W><V><A><A><C><R><S><P><D><L><L><D><D><V><R><R><G><L><A><V><L><T><A><S><G><T><V><L><R><R><G><F><S><T><G><T><T><A><A><A><A><C><K><A><A><I><L><S><L><A><C><D><T><V><R><E><V><D><V><T><L><P><C><G><I><A><V><R><L><A><V><D><G><Y><R><G><Q><A><S><C><R><K><D><A><G><D><Y><T><A><D><V><T><G><G...
Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A.<BOP>
A3CSU7
B7XIV9
HSF_ENTBH
Heat shock factor protein
Enterocytozoon
<M><A><K><R><K><E><V><T><E><I><S><E><M><D><I><K><K><S><G><F><V><N><R><L><Y><R><E><T><C><D><I><S><N><K><Y><I><K><F><D><D><D><G><D><K><L><I><I><P><N><K><I><D><F><I><K><K><A><L><N><K><I><S><S><T><K><D><Y><S><S><F><V><R><Q><L><N><N><Y><G><F><T><K><I><K><L><D><N><G><D><S><N><C><D><I><Y><Y><H><Q><N><F><H><R><D><H><P><D><L><I...
DNA-binding transcription factor that specifically binds heat shock promoter elements (HSE) and activates transcription.<BOP>
B7XIV9
A4W5D0
ACEK_ENT38
Isocitrate dehydrogenase kinase/phosphatase
Enterobacter
<M><S><R><G><L><E><L><L><I><A><Q><T><I><L><Q><G><F><D><A><Q><Y><G><R><F><L><E><V><T><S><G><A><Q><Q><R><F><E><H><A><D><W><H><A><V><Q><Q><A><M><K><Q><R><I><H><L><Y><D><H><H><V><G><L><V><V><E><Q><L><R><C><I><T><E><G><K><S><T><D><V><D><F><L><L><R><V><K><E><H><Y><T><H><L><L><P><D><Y><P><R><F><E><I><A><E><S><F><F><N><S><V><Y...
Bifunctional enzyme which can phosphorylate or dephosphorylate isocitrate dehydrogenase (IDH) on a specific serine residue. This is a regulatory mechanism which enables bacteria to bypass the Krebs cycle via the glyoxylate shunt in response to the source of carbon. When bacteria are grown on glucose, IDH is fully activ...
A4W5D0
Q9UBL9
P2RX2_HUMAN
Purinergic receptor
Homo
<M><A><A><A><Q><P><K><Y><P><A><G><A><T><A><R><R><L><A><R><G><C><W><S><A><L><W><D><Y><E><T><P><K><V><I><V><V><R><N><R><R><L><G><V><L><Y><R><A><V><Q><L><L><I><L><L><Y><F><V><W><Y><V><F><I><V><Q><K><S><Y><Q><E><S><E><T><G><P><E><S><S><I><I><T><K><V><K><G><I><T><T><S><E><H><K><V><W><D><V><E><E><Y><V><K><P><P><E><G><G><S><V...
Ion channel gated by extracellular ATP involved in a variety of cellular responses, such as excitatory postsynaptic responses in sensory neurons, neuromuscular junctions (NMJ) formation, hearing, perception of taste and peristalsis. In the inner ear, regulates sound transduction and auditory neurotransmission, outer ha...
Q9UBL9
Q07Z51
FETP_SHEFN
Probable Fe(2+)-trafficking protein
Shewanella
<M><A><R><T><V><H><C><Q><H><L><N><K><S><A><D><G><L><D><F><Q><L><Y><P><G><E><L><G><K><R><I><F><D><N><I><G><K><E><A><W><G><L><W><Q><K><K><Q><T><M><L><I><N><E><K><K><L><N><M><M><N><V><D><D><R><K><F><L><E><E><Q><M><T><N><F><L><F><E><G><K><D><V><E><I><E><G><Y><V><P><P><A><E><D><E>
Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes.<BOP>
Q07Z51
Q7CVH1
KATG_AGRFC
Peroxidase/catalase
Agrobacterium tumefaciens complex
<M><D><A><T><S><K><P><A><G><K><C><P><V><M><H><G><G><N><T><A><S><G><K><S><V><T><E><W><W><P><N><A><L><N><L><D><I><L><H><Q><H><D><T><K><T><N><P><L><G><T><S><F><N><Y><R><E><A><L><K><T><L><D><V><E><A><L><K><A><D><L><R><A><L><M><T><D><S><Q><E><W><W><P><A><D><W><G><S><Y><V><G><M><M><A><R><V><T><W><H><A><A><G><S><Y><R><V><T><D...
Bifunctional enzyme with both catalase and broad-spectrum peroxidase activity.<BOP>
Q7CVH1
P46956
PHO86_YEAST
Inorganic phosphate transporter PHO86
Saccharomyces
<M><A><V><Q><Q><R><K><K><K><E><G><R><K><S><D><K><N><A><P><S><V><P><Q><V><D><A><S><L><D><K><P><L><D><I><D><A><P><P><T><I><Y><S><V><N><L><K><P><E><Y><G><T><A><A><L><N><L><S><A><D><F><I><R><Q><E><Q><A><L><A><N><K><Y><L><F><F><H><P><V><I><L><V><V><L><T><I><G><L><L><I><Y><L><T><P><R><I><V><F><P><I><R><N><T><G><S><V><A><G><W...
Involved in the uptake of inorganic phosphate.<BOP>
P46956
P10720
PF4V_HUMAN
Platelet factor 4 variant(6-74)
Homo
<M><S><S><A><A><R><S><R><L><T><R><A><T><R><Q><E><M><L><F><L><A><L><L><L><L><P><V><V><V><A><F><A><R><A><E><A><E><E><D><G><D><L><Q><C><L><C><V><K><T><T><S><Q><V><R><P><R><H><I><T><S><L><E><V><I><K><A><G><P><H><C><P><T><A><Q><L><I><A><T><L><K><N><G><R><K><I><C><L><D><L><Q><A><L><L><Y><K><K><I><I><K><E><H><L><E><S>
Inhibitor of angiogenesis. Inhibitor of endothelial cell chemotaxis (in vitro).<BOP>
P10720
P53390
MEP3_YEAST
Ammonium transporter MEP3
Saccharomyces
<M><A><R><G><D><G><H><L><W><T><E><T><Y><D><S><S><T><V><A><F><M><I><L><G><A><A><L><V><F><F><M><V><P><G><L><G><F><L><Y><S><G><L><A><R><R><K><S><A><L><A><L><I><W><V><V><I><M><A><T><L><V><G><I><L><Q><W><Y><F><W><G><Y><S><L><A><F><S><K><T><A><T><N><N><K><F><I><G><N><L><D><S><F><G><F><R><N><V><Y><G><K><I><S><D><D><S><T><Y><P...
Transporter for ammonium (both charged and uncharged NH3 and NH4) to use as a nitrogen source. The affinity of MEP2 is about twenty times higher than that of MEP1. MEP3 has the lowest affinity.<BOP>
P53390
B9MGN9
RIMP_ACIET
Ribosome maturation factor RimP
Diaphorobacter
<M><A><L><Q><Q><I><V><E><Q><T><V><A><G><L><G><Y><D><L><V><E><I><E><R><S><A><G><G><L><L><R><I><T><I><D><L><V><W><V><P><P><T><D><E><V><S><A><A><V><G><V><E><Q><F><I><T><V><E><D><C><E><K><V><T><R><Q><L><Q><F><A><L><E><V><E><G><V><D><Y><T><R><L><E><V><S><S><P><G><I><D><R><L><L><R><N><E><A><D><F><K><R><F><E><G><E><V><I><D><I...
Required for maturation of 30S ribosomal subunits.<BOP>
B9MGN9
Q8FEM8
HIGB_ECOL6
Toxin HigB
Escherichia
<M><H><I><I><S><K><A><P><F><E><E><C><A><R><K><Y><P><N><D><A><L><A><L><H><S><L><Y><R><V><I><K><E><T><D><F><S><T><P><E><E><M><R><T><A><F><P><N><L><D><N><F><K><Y><R><N><K><W><Y><V><L><D><V><G><G><N><N><L><R><V><I><A><Y><I><N><F><V><N><K><R><F><F><V><K><H><I><T><N><H><A><E><Y><D><K><L><T><R><Y><Y><R><E><N><K><E>
Toxic component of a type II toxin-antitoxin (TA) system. A probable translation-dependent mRNA interferase. Probably counteracted by antitoxin HigA.<BOP>
Q8FEM8
P41510
PME_BRANA
Pectin methylesterase
Brassica
<M><A><V><G><K><I><V><I><S><V><A><S><M><L><L><V><V><G><V><A><I><G><V><V><T><F><V><N><K><G><G><G><A><G><G><D><K><T><L><N><S><H><Q><K><A><V><E><S><L><C><A><S><A><T><D><K><G><S><C><A><K><T><L><D><P><V><K><S><D><D><P><S><K><L><I><K><A><F><M><L><A><T><K><D><A><V><T><K><S><T><N><F><T><A><S><T><E><E><G><M><G><K><N><I><N><A><T...
Acts in the modification of cell walls via demethylesterification of cell wall pectin.<BOP>
P41510
B2HSN4
RL2_MYCMM
50S ribosomal protein L2
Mycobacterium
<M><A><I><R><K><Y><K><P><T><T><P><G><R><R><G><A><S><V><S><D><F><A><E><I><T><R><S><T><P><E><K><S><L><V><R><P><L><H><G><H><G><G><R><N><A><H><G><R><I><T><T><R><H><K><G><G><G><H><K><R><A><Y><R><V><I><D><F><R><R><N><D><K><D><G><V><N><A><K><V><A><H><I><E><Y><D><P><N><R><T><A><R><I><A><L><L><H><Y><L><D><G><E><K><R><Y><I><I><A...
One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.<...
B2HSN4
A4STH3
NORW_AERS4
Flavorubredoxin reductase
Aeromonas
<M><K><A><A><T><L><S><E><A><G><V><S><R><E><I><L><V><I><G><S><G><F><A><A><Q><Q><L><V><K><S><L><R><K><L><D><A><E><Q><P><I><R><L><I><T><A><D><S><G><D><E><Y><N><K><P><D><L><S><H><V><V><S><R><G><C><T><A><A><A><M><T><R><L><S><G><S><D><F><A><E><Q><Q><R><I><A><L><V><P><H><C><P><V><L><G><I><D><P><A><R><R><I><V><M><T><V><Q><G><E...
One of at least two accessory proteins for anaerobic nitric oxide (NO) reductase. Reduces the rubredoxin moiety of NO reductase.<BOP>
A4STH3
C3KWF7
FABH_CLOB6
3-oxoacyl-[acyl-carrier-protein] synthase III
Clostridium
<M><S><N><I><S><V><I><G><T><G><S><Y><V><P><N><N><I><I><T><N><D><F><L><S><T><I><V><D><T><S><D><E><W><I><R><T><R><T><G><I><L><E><R><R><I><S><K><E><E><N><T><I><Y><M><A><I><E><S><A><K><E><A><I><K><N><A><N><I><E><A><N><D><L><D><L><I><I><V><A><T><L><T><P><D><N><F><M><P><S><T><A><C><S><V><Q><K><E><I><G><A><I><N><A><L><C><F><D...
Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-A...
C3KWF7
Q493C0
LPXA_BLOPB
Acyl-[acyl-carrier-protein]--UDP-N-acetylglucosamine O-acyltransferase
Candidatus Blochmannia
<M><I><H><Q><S><A><I><I><H><P><S><S><I><I><E><E><G><A><I><I><H><D><N><V><H><I><G><P><F><C><F><I><G><A><Q><V><E><I><G><A><R><T><L><L><K><S><H><I><V><I><N><G><I><T><Q><I><G><E><D><N><Q><I><Y><Q><F><A><S><L><G><E><V><N><Q><D><L><K><Y><A><K><E><S><T><R><I><E><I><G><H><Y><N><Q><I><R><E><S><V><T><I><H><R><G><T><I><Q><G><K><K...
Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.<BOP>
Q493C0
A1VYA9
SYS_CAMJJ
Seryl-tRNA(Ser/Sec) synthetase
Campylobacter
<M><L><D><L><K><N><L><Q><N><N><F><D><E><V><A><K><K><L><K><N><K><K><V><D><E><N><I><L><K><K><L><A><E><L><F><A><S><L><K><K><E><K><T><A><L><E><E><F><Q><A><F><Q><N><K><F><S><K><E><L><A><T><A><E><D><K><E><S><L><K><A><K><L><S><E><N><K><S><K><I><N><E><Q><S><A><K><V><N><A><L><E><N><E><L><E><E><I><A><H><A><I><P><N><I><P><D><E><C...
Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).<BOP>
A1VYA9
C3MAY3
RL2_SINFN
50S ribosomal protein L2
Sinorhizobium
<M><A><L><K><S><F><N><P><T><T><P><S><Q><R><Q><L><V><I><V><D><R><A><G><L><Y><K><G><K><P><V><K><T><L><T><E><G><L><S><S><K><G><G><R><N><N><L><G><R><I><T><V><R><F><Q><G><G><G><H><K><R><T><Y><R><L><V><D><F><K><R><R><K><F><D><V><E><G><T><V><E><R><L><E><Y><D><P><N><R><T><A><F><I><A><L><V><N><Y><A><D><G><E><Q><A><Y><I><L><A><P...
One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.<...
C3MAY3
A6BM08
ATPA_GNEPA
F-ATPase subunit alpha
Gnetum
<M><M><I><T><I><R><P><D><E><I><S><S><I><I><R><E><Q><I><E><Q><Y><N><N><E><I><Q><V><V><N><M><G><T><V><L><Q><V><G><D><G><I><A><R><I><H><G><L><Y><E><V><M><A><G><E><L><V><E><F><E><D><S><T><V><G><I><A><L><N><L><E><T><Q><N><V><G><V><V><L><M><G><D><G><L><T><I><K><E><G><S><F><V><K><T><T><G><K><I><A><Q><I><P><V><S><D><A><F><L><G...
Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit.<BOP>
A6BM08
P10496
GRP2_PHAVU
Glycine-rich cell wall structural protein 1.8
Phaseolus
<M><A><T><I><H><R><L><P><S><L><V><F><L><V><L><L><A><L><G><V><C><S><A><R><R><A><L><L><T><L><D><A><G><Y><G><L><G><H><G><T><G><G><G><Y><G><G><A><A><G><S><Y><G><G><G><G><G><G><G><S><G><G><G><G><G><Y><A><G><E><H><G><V><V><G><Y><G><G><G><S><G><G><G><Q><G><G><G><V><G><Y><G><G><D><Q><G><A><G><Y><G><G><G><G><G><S><G><G><G><G><G...
Responsible for plasticity of the cell wall.<BOP>
P10496
A5F554
RL5_VIBC3
50S ribosomal protein L5
Vibrio
<M><A><K><L><H><D><Y><Y><K><S><S><V><V><A><E><L><T><K><Q><F><S><Y><T><S><V><M><Q><V><P><R><I><E><K><I><T><L><N><M><G><V><G><E><A><I><N><D><K><K><L><L><E><N><A><A><S><D><M><A><I><I><S><G><Q><K><P><L><I><T><K><A><R><K><S><V><A><G><F><K><I><R><E><G><Y><P><I><G><C><K><V><T><L><R><G><E><R><M><W><D><F><L><E><R><L><I><S><I><A...
This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement...
A5F554
Q12006
PFA4_YEAST
Protein fatty acyltransferase 4
Saccharomyces
<M><P><V><K><L><R><W><P><W><L><G><I><A><I><P><T><F><L><I><S><F><I><G><Y><G><A><H><Y><F><I><L><S><N><F><L><S><V><P><K><Q><I><T><F><E><F><C><L><S><M><I><W><L><S><Y><Y><L><A><I><C><T><N><P><G><R><P><L><P><N><Y><K><P><P><P><D><I><W><R><N><F><C><K><K><C><Q><S><Y><K><P><E><R><S><H><H><C><K><T><C><N><Q><C><V><L><M><M><D><H><H...
Mediates the reversible addition of palmitate to target proteins, thereby regulating their membrane association and biological function. Palmitoylates several amino acid permeases . Palmitoylates chitin synthase CHS3, which is required for its proper export from the ER . Can palmitoylate RAS2 in vitro .<BOP>
Q12006
A9HVE9
BIOF_BORPD
8-amino-7-ketopelargonate synthase
Bordetella
<M><Q><L><L><D><N><L><D><A><A><L><R><K><L><D><A><Q><H><L><R><R><R><R><R><T><A><E><S><P><C><A><P><H><V><R><V><D><G><R><D><M><L><A><F><C><S><N><D><Y><L><G><L><A><A><H><P><V><I><V><A><A><L><A><E><G><A><A><R><Y><G><A><G><S><G><A><S><H><L><I><S><G><H><S><H><A><H><A><Q><L><E><E><R><L><A><N><M><L><A><P><H><L><E><Q><P><R><A><L...
Catalyzes the decarboxylative condensation of pimeloyl-[acyl-carrier protein] and L-alanine to produce 8-amino-7-oxononanoate (AON), [acyl-carrier protein], and carbon dioxide.<BOP>
A9HVE9
A4T174
MEND_MYCGI
Menaquinone biosynthesis protein MenD
Mycolicibacterium
<M><N><P><S><T><A><Q><A><R><V><V><V><D><E><L><V><R><G><G><V><R><D><V><V><L><C><P><G><S><R><N><A><P><L><A><F><A><L><H><D><A><D><R><A><G><R><L><R><L><H><V><R><I><D><E><R><T><A><G><F><L><A><I><G><L><A><V><A><E><R><A><P><V><C><V><A><M><T><S><G><T><A><V><A><N><L><G><P><A><V><V><E><A><N><Y><A><R><V><P><L><I><V><L><T><A><N><R...
Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC).<BOP>
A4T174
Q5E3F0
FABZ_ALIF1
Beta-hydroxyacyl-ACP dehydratase
Aliivibrio
<M><T><R><E><N><K><T><L><N><I><T><E><I><Q><E><L><L><P><H><R><Y><P><F><L><L><V><D><R><V><T><D><F><E><E><E><K><Y><L><H><A><I><K><N><V><S><V><N><E><P><Q><F><T><G><H><F><P><Q><M><P><I><F><P><G><V><L><I><L><E><A><M><A><Q><A><T><G><L><L><A><F><K><S><F><G><A><P><A><E><N><E><L><Y><Y><F><A><S><I><D><K><A><K><F><R><K><P><V><V><P...
Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs.<BOP>
Q5E3F0
Q0ACA3
LIPB_ALKEH
Octanoyl-[acyl-carrier-protein]-protein N-octanoyltransferase
Alkalilimnicola
<M><P><P><S><P><L><T><D><I><Q><V><R><Y><L><G><R><R><D><Y><R><E><T><W><S><A><M><R><R><Y><T><D><E><R><G><P><D><T><P><D><Q><L><W><V><V><S><H><P><P><V><Y><T><L><G><Q><A><G><R><R><E><H><I><L><D><P><G><E><I><P><V><V><E><T><D><R><G><G><Q><V><T><Y><H><G><P><G><Q><I><V><L><Y><P><L><L><D><L><R><R><W><G><L><G><V><R><S><L><V><S><A...
Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate.<BOP>
Q0ACA3
Q57JQ5
CCA_SALCH
Phosphatase
Salmonella
<M><K><I><Y><L><V><G><G><A><V><R><D><A><L><L><G><L><P><V><K><D><K><D><W><V><V><V><G><A><T><P><Q><E><M><L><D><A><G><Y><Q><Q><V><G><R><D><F><P><V><F><L><H><P><Q><T><H><E><E><Y><A><L><A><R><T><E><R><K><S><G><S><G><Y><T><G><F><T><C><Y><A><A><P><D><V><T><L><E><A><D><L><Q><R><R><D><L><T><I><N><A><L><A><R><D><D><D><G><Q><I><I...
Catalyzes the addition and repair of the essential 3'-terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate. Also shows phosphatase, 2'-nucleotidase a...
Q57JQ5
A8ESZ9
UREE_ALIB4
Urease accessory protein UreE
Aliarcobacter
<M><T><F><S><V><I><K><K><V><I><E><I><K><K><D><I><P><F><S><D><E><V><E><L><S><W><F><D><M><Q><K><P><N><L><T><A><V><T><K><K><G><V><N><L><V><V><K><A><K><F><T><H><L><H><E><N><D><I><L><V><C><E><D><G><I><G><I><K><V><K><R><S><E><D><E><I><F><S><L><E><F><S><D><A><L><T><F><A><K><T><A><Y><E><I><G><N><R><H><Q><P><L><Q><I><E><E><F><K...
Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly.<BOP>
A8ESZ9
A4FZM0
ILVD_METM5
Dihydroxy-acid dehydratase
Methanococcus
<M><I><S><D><N><V><K><K><G><V><I><R><S><P><N><R><A><L><L><K><A><C><G><Y><S><D><E><D><M><E><K><P><F><I><G><V><V><N><S><F><T><E><V><V><P><G><H><I><H><L><K><T><L><S><D><A><V><K><H><G><V><Y><A><N><G><G><T><P><F><E><F><N><T><I><G><I><C><D><G><I><A><M><G><H><E><G><M><K><Y><S><L><P><S><R><E><I><I><A><D><A><V><E><S><M><A><R><A...
Functions in the biosynthesis of branched-chain amino acids. Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (...
A4FZM0
Q3KLL2
HEMH_CHLTA
Protoheme ferro-lyase
Chlamydia
<M><V><T><Y><L><L><A><N><F><G><G><P><R><T><S><Q><E><I><V><S><F><L><Q><A><L><L><T><D><R><D><V><T><G><G><M><I><P><S><M><L><H><R><P><L><F><S><Y><I><A><K><R><R><A><P><H><V><A><R><Q><Y><A><Y><L><G><G><G><S><P><I><F><Q><D><T><E><R><L><A><Q><N><L><S><Q><E><L><Q><A><S><V><I><P><F><H><R><Y><L><P><E><T><H><R><E><T><L><Q><A><L><Q...
Catalyzes the ferrous insertion into protoporphyrin IX.<BOP>
Q3KLL2
A1AVR9
NUOH_RUTMC
NDH-1 subunit H
Candidatus Ruthia
<M><E><L><W><Q><A><F><V><Q><M><V><Y><T><L><T><P><W><F><D><G><T><I><A><S><I><L><I><I><L><I><K><A><I><T><L><V><I><P><L><M><L><V><V><A><Y><F><T><Y><A><E><R><K><V><I><G><Y><M><Q><L><R><I><G><P><N><R><V><G><P><K><G><W><L><Q><P><I><A><D><A><L><K><L><M><T><K><E><I><I><F><P><T><K><A><N><I><Y><L><F><L><L><A><P><V><L><A><I><A><P...
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are t...
A1AVR9
Q4UMQ9
SECY_RICFE
Protein translocase subunit SecY
spotted fever group
<M><G><Q><N><F><S><K><K><S><G><N><D><L><V><S><R><I><V><F><T><I><L><I><L><I><V><C><R><F><G><S><F><I><P><I><P><G><I><D><S><I><A><L><S><S><V><A><E><K><N><Q><S><G><I><L><G><M><F><N><M><L><S><G><G><S><L><G><R><M><S><I><F><A><L><A><I><M><P><Y><I><T><A><S><I><I><I><Q><L><M><S><V><A><Y><K><P><L><E><N><L><K><K><E><G><E><V><G><K...
The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydr...
Q4UMQ9
O74428
TCO89_SCHPO
Target of rapamycin complex 1 subunit tco89
Schizosaccharomyces
<M><E><R><P><S><L><S><R><R><T><S><S><S><T><V><S><T><D><G><E><G><V><Y><S><R><S><T><K><E><R><K><R><N><F><I><V><N><S><R><L><K><R><G><G><G><H><V><R><V><N><R><S><G><R><L><G><S><V><T><M><R><P><S><A><L><T><R><A><H><S><Q><N><P><N><S><S><L><V><N><N><S><S><A><V><S><H><L><T><K><Q><R><S><L><N><D><L><H><E><L><N><G><P><K><H><V><A><K...
Component of TORC1, which regulates multiple cellular processes to control cell growth in response to environmental signals. Tor2 is essential for growth. Nutrient limitation and environmental stress signals cause inactivation of TORC1. Active TORC1 positively controls cell growth and ribosome biogenesis by regulating ...
O74428
Q7VJ31
PROB_HELHP
Gamma-glutamyl kinase
Helicobacter
<M><Q><K><P><R><I><V><L><K><I><G><S><S><N><L><C><N><G><K><I><I><D><K><T><Q><I><K><A><L><A><Q><I><I><S><E><L><K><M><R><F><D><V><I><L><V><S><S><G><A><V><A><S><G><H><T><T><L><H><I><D><R><N><T><L><Q><N><K><Q><A><L><A><S><I><G><Q><P><L><L><M><E><S><Y><R><E><A><L><K><D><Y><A><I><P><T><A><Q><L><L><L><V><W><R><D><F><D><S><R><K...
Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.<BOP>
Q7VJ31
P20718
GRAH_HUMAN
Cytotoxic serine protease C
Homo
<M><Q><P><F><L><L><L><L><A><F><L><L><T><P><G><A><G><T><E><E><I><I><G><G><H><E><A><K><P><H><S><R><P><Y><M><A><F><V><Q><F><L><Q><E><K><S><R><K><R><C><G><G><I><L><V><R><K><D><F><V><L><T><A><A><H><C><Q><G><S><S><I><N><V><T><L><G><A><H><N><I><K><E><Q><E><R><T><Q><Q><F><I><P><V><K><R><P><I><P><H><P><A><Y><N><P><K><N><F><S><N...
Cytotoxic chymotrypsin-like serine protease with preference for bulky and aromatic residues at the P1 position and acidic residues at the P3' and P4' sites. Probably necessary for target cell lysis in cell-mediated immune responses. Participates in the antiviral response via direct cleavage of several proteins essentia...
P20718
Q8U0B3
LYSK_PYRFU
Putative [LysW]-lysine/[LysW]-ornithine hydrolase
Pyrococcus
<M><I><S><T><E><E><K><I><E><F><L><K><R><L><V><E><I><Y><S><P><T><G><K><E><N><G><V><A><K><F><L><I><K><S><F><E><N><Y><G><I><E><A><Y><L><D><D><V><G><N><V><I><A><V><K><K><G><K><G><P><L><I><L><L><A><G><H><M><D><T><V><P><G><Y><I><P><V><R><I><E><N><G><E><L><W><G><R><G><A><V><D><A><K><G><P><L><A><T><F><F><F><A><T><I><E><S><D><A...
Catalyzes the release of L-lysine from [LysW]-gamma-L-lysine and the release of L-ornithine from [LysW]-L-ornithine.<BOP>
Q8U0B3
Q61900
SMR3A_MOUSE
Submaxillary gland androgen-regulated protein 1
Mus
<M><K><P><L><N><L><V><L><G><L><C><I><L><V><G><C><F><L><S><C><E><C><H><R><G><P><R><R><H><D><P><R><G><P><F><P><P><P><P><P><P><H><G><P><G><I><G><R><P><H><P><P><P><F><G><P><G><I><G><R><P><P><P><P><P><F><G><P><G><I><G><R><P><P><P><P><P><P><C><P><P><V><P><P><H><P><R><P><P><S><N><P><S><P><P><P><T><P><S><I><P><P><T><G><P><P><T...
May play a role in protection or detoxification.<BOP>
Q61900
Q4L9R7
TRHO_STAHJ
tRNA hydroxylation protein O
Staphylococcus
<M><D><Y><R><V><L><L><Y><Y><K><Y><T><T><I><D><D><P><E><T><F><A><A><E><H><L><E><F><C><K><S><N><N><L><K><G><R><I><L><V><S><T><E><G><I><N><G><T><L><S><G><T><K><E><D><T><D><K><Y><I><E><H><M><H><S><D><E><R><F><A><D><M><T><F><K><I><D><E><A><E><G><H><A><F><K><K><M><H><V><R><P><R><N><E><I><V><A><L><G><L><E><D><D><V><D><P><R><V...
Catalyzes oxygen-dependent 5-hydroxyuridine (ho5U) modification at position 34 in tRNAs.<BOP>
Q4L9R7
A1JLB3
SYE_YERE8
Glutamyl-tRNA synthetase
Yersinia
<M><K><I><K><T><R><F><A><P><S><P><T><G><Y><L><H><V><G><G><A><R><T><A><L><Y><S><W><L><F><T><R><H><F><G><G><E><F><V><L><R><I><E><D><T><D><L><E><R><S><T><Q><E><A><I><D><A><I><M><D><G><M><N><W><L><N><L><D><W><D><E><G><P><Y><F><Q><T><K><R><F><D><R><Y><N><A><V><I><D><Q><M><L><E><N><G><T><A><Y><R><C><Y><C><S><K><E><R><L><D><E...
Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).<BOP>
A1JLB3
P50476
HOX3_XENLA
Homeobox protein XHOX-3
Xenopus
<M><E><G><R><K><E><M><L><M><Y><L><E><G><G><Q><L><G><T><L><V><G><K><R><M><A><H><L><S><D><A><V><G><S><P><M><A><E><S><Q><D><K><L><V><P><K><S><P><R><A><G><P><I><A><P><T><D><R><A><E><E><S><E><V><E><V><G><Q><A><T><G><Q><Q><R><S><R><S><P><Q><L><R><I><S><S><P><H><P><P><A><H><S><D><S><L><S><T><K><G><Q><H><S><S><S><D><T><E><S><D...
May be required for posterior development and development of normal embryonic axial pattern.<BOP>
P50476
Q867A9
EDN2_BOVIN
Preproendothelin-2
Bos
<M><P><T><A><L><C><S><I><A><L><A><L><L><V><A><L><H><E><G><K><S><Q><A><A><T><T><P><I><P><E><Q><P><A><P><L><P><R><A><R><G><S><H><L><R><T><R><R><C><S><C><S><S><W><L><D><K><E><C><V><Y><F><C><H><L><D><I><I><W><V><N><T><P><G><Q><T><A><P><Y><G><L><G><N><P><P><R><R><R><R><R><S><L><P><R><R><C><E><C><Y><S><A><R><D><P><A><C><A><T...
Endothelins are endothelium-derived vasoconstrictor peptides.<BOP>
Q867A9