accession stringlengths 6 10 | name stringlengths 6 11 | Full Name stringlengths 1 147 ⌀ | taxon stringlengths 3 46 ⌀ | sequence stringlengths 48 2.3k | function stringlengths 11 1.34k | AlphaFoldDB stringlengths 6 10 |
|---|---|---|---|---|---|---|
P0C1J1 | PPIL2_RHIO9 | Rotamase | Rhizopus | <M><G><K><W><T><D><K><L><Y><I><T><H><S><E><W><S><G><E><V><G><Q><H><S><A><S><S><G><I><T><G><R><N><S><S><G><G><F><K><R><L><P><F><Y><C><C><S><L><S><L><Q><P><F><E><H><P><V><C><T><P><D><G><I><I><F><D><L><M><N><I><I><P><Y><I><K><K><Y><G><T><N><P><V><T><G><E><K><L><E><T><K><N><L><I><K><L><H><F><H><K><N><D><K><D><E><Y><F><C><P... | May catalyze the cis-trans isomerization of proline imidic peptide bonds in oligopeptides thereby assisting the folding of proteins. May also function as a chaperone, playing a role in intracellular transport of proteins. May also have a protein ubiquitin ligase activity acting as an E3 ubiquitin protein ligase or as a... | P0C1J1 |
Q2KW44 | PYRD_BORA1 | Dihydroorotate oxidase | Bordetella | <M><S><I><L><F><N><A><Y><P><L><A><R><P><A><L><F><A><M><D><A><E><T><A><H><E><V><T><L><A><S><L><Q><R><A><Y><D><C><G><T><T><R><R><W><L><H><D><Q><P><Q><L><P><T><T><L><M><G><M><T><L><R><N><P><V><G><L><A><A><G><L><D><K><N><G><A><F><I><D><A><L><G><N><L><G><F><G><F><V><E><V><G><T><V><T><P><R><A><Q><S><G><N><P><K><P><R><M><F><R... | Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor.<BOP> | Q2KW44 |
Q7SCW9 | RMT2_NEUCR | Type IV protein arginine N-methyltransferase | Neurospora | <M><A><D><N><D><S><I><S><V><R><I><S><E><D><C><P><P><E><I><Q><R><M><L><T><A><A><W><A><H><D><V><D><T><V><K><K><L><I><D><T><P><E><V><A><R><G><Q><D><P><K><T><G><E><S><P><L><H><A><A><I><R><S><C><G><A><P><S><E><D><D><T><P><E><D><H><E><K><A><K><A><T><V><S><E><L><L><M><W><G><A><I><W><N><D><V><D><N><N><N><E><T><P><G><C><V><A><A... | S-adenosyl-L-methionine-dependent protein-arginine N-methyltransferase that methylates the delta-nitrogen atom of arginine residues to form N5-methylarginine (type IV) in target proteins. Monomethylates ribosomal protein L12.<BOP> | Q7SCW9 |
Q15PD3 | CH60_PSEA6 | Chaperonin-60 | Pseudoalteromonas | <M><A><A><K><E><V><R><F><S><D><D><A><R><V><K><M><L><A><G><V><N><I><L><A><N><A><V><K><V><T><L><G><P><K><G><R><N><V><V><L><D><K><S><F><G><A><P><T><I><T><K><D><G><V><S><V><A><K><E><I><E><L><E><D><K><F><E><N><M><G><A><Q><M><V><K><E><V><A><S><K><A><N><D><E><A><G><D><G><T><T><T><A><T><V><L><A><Q><S><I><V><T><E><G><L><K><A><V... | Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.<BOP> | Q15PD3 |
Q6XLL6 | KAX69_OPICA | OcKTx4 | Opistophthalmus | <M><N><A><K><F><I><L><L><L><L><V><V><T><T><T><T><L><L><P><D><A><K><G><A><E><I><I><R><C><S><G><T><R><E><C><Y><A><P><C><Q><K><L><T><G><C><L><N><A><K><C><M><N><K><A><C><K><C><Y><G><C><V> | Inhibits Kv1.2/KCNA2 and Kv1.3/KCNA3 voltage-gated potassium channels .<BOP> | Q6XLL6 |
C3PLX7 | TIG_RICAE | PPIase | spotted fever group | <M><G><I><T><I><L><K><N><E><G><L><D><F><H><A><R><I><S><T><P><L><S><E><I><D><D><D><I><Q><K><E><L><L><D><L><T><K><K><V><K><I><A><G><F><R><V><G><K><V><P><V><S><I><V><K><K><K><Y><G><T><S><V><R><N><D><I><I><E><R><R><I><N><H><S><V><N><H><V><I><K><E><H><N><L><N><I><I><G><R><P><T><I><E><E><L><Q><N><E><S><D><K><A><L><E><F><T><V... | Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase.<BOP> | C3PLX7 |
A6VYK6 | RSMH_MARMS | rRNA (cytosine-N(4)-)-methyltransferase RsmH | Marinomonas | <M><T><K><T><M><A><E><H><I><S><V><M><L><N><E><S><V><D><M><L><V><T><D><T><N><G><L><Y><V><D><G><T><F><G><R><G><G><H><T><R><L><V><L><D><R><L><D><K><G><R><L><L><G><F><D><K><D><P><V><A><I><G><H><G><K><L><L><E><Q><E><D><A><R><F><S><I><V><Q><D><S><F><A><N><M><A><E><H><I><T><N><V><F><G><V><D><R><V><D><G><V><M><M><D><L><G><V><S... | Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.<BOP> | A6VYK6 |
A2CAG3 | ACCD_PROM3 | Acetyl-coenzyme A carboxylase carboxyl transferase subunit beta | Prochlorococcus | <M><S><L><F><D><W><F><A><D><R><R><K><G><Q><F><V><G><K><V><S><Q><E><T><E><E><S><D><G><L><W><V><K><C><P><E><C><G><Q><V><V><Y><R><K><D><L><H><A><N><A><S><V><C><S><N><C><G><Y><H><H><R><I><D><S><D><E><R><I><V><L><I><A><D><Q><G><S><F><K><S><L><D><R><N><L><S><P><T><D><P><L><G><F><K><D><R><R><A><Y><A><D><R><L><R><E><S><Q><A><S... | Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA.<BOP> | A2CAG3 |
Q8IZT8 | HS3S5_HUMAN | Heparan sulfate D-glucosaminyl 3-O-sulfotransferase 5 | Homo | <M><L><F><K><Q><Q><A><W><L><R><Q><K><L><L><V><L><G><S><L><A><V><G><S><L><L><Y><L><V><A><R><V><G><S><L><D><R><L><Q><P><I><C><P><I><E><G><R><L><G><G><A><R><T><Q><A><E><F><P><L><R><A><L><Q><F><K><R><G><L><L><H><E><F><R><K><G><N><A><S><K><E><Q><V><R><L><H><D><L><V><Q><Q><L><P><K><A><I><I><I><G><V><R><K><G><G><T><R><A><L><L... | Sulfotransferase that utilizes 3'-phospho-5'-adenylyl sulfate (PAPS) to catalyze the transfer of a sulfo group to position 3 of glucosamine residues in heparan. Catalyzes the rate limiting step in the biosynthesis of heparan sulfate (HSact). This modification is a crucial step in the biosynthesis of anticoagulant hepar... | Q8IZT8 |
B2S9N1 | ATPF2_BRUA1 | F-type ATPase subunit b 2 | Brucella | <M><D><A><T><F><W><A><F><I><A><L><V><I><F><V><A><I><V><V><Y><M><K><V><P><G><M><I><G><R><T><L><D><E><R><A><D><R><I><K><K><E><L><E><E><A><R><T><L><R><E><E><A><Q><Q><L><L><A><E><Y><H><R><K><R><K><E><A><E><K><E><A><G><D><I><V><A><S><A><E><R><E><A><K><A><L><L><E><E><A><K><R><A><T><E><E><Y><V><A><R><R><N><K><L><A><E><Q><K><I... | Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0).<BOP> | B2S9N1 |
Q1GEU7 | ATPG_RUEST | F-ATPase gamma subunit | unclassified Ruegeria | <M><P><S><L><K><D><L><K><N><R><I><S><S><V><K><N><T><R><K><I><T><K><A><M><Q><M><V><A><A><A><K><L><R><R><A><Q><E><A><A><E><D><A><R><P><Y><A><E><R><F><N><A><V><M><A><G><L><A><A><S><V><G><Q><S><D><T><A><P><K><L><L><A><G><T><G><S><D><Q><V><Q><L><L><V><V><M><T><A><E><R><G><L><C><G><G><F><N><A><N><I><A><K><L><A><R><Q><K><V><L... | Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.<BOP> | Q1GEU7 |
Q710S3 | CYB_JACJA | Ubiquinol-cytochrome-c reductase complex cytochrome b subunit | Jaculus | <M><T><N><I><R><K><T><H><P><L><M><K><I><V><N><E><S><F><I><D><L><P><T><P><S><N><I><S><A><W><W><N><F><G><S><L><L><G><M><C><L><I><I><Q><I><A><T><G><L><F><L><A><M><H><Y><T><S><D><T><T><T><A><F><S><S><V><A><H><I><C><R><D><V><N><Y><G><W><L><I><R><Y><L><H><A><N><G><A><S><M><F><F><I><C><L><F><L><H><V><G><R><G><L><Y><Y><G><S><Y... | Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain. The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c. Contributes to the generation of a proton gradient across the mitochondrial membrane that is... | Q710S3 |
Q1JDC8 | YIDD_STRPB | Putative membrane protein insertion efficiency factor | Streptococcus | <M><M><K><K><L><L><I><V><S><V><K><A><Y><Q><K><Y><I><S><P><L><S><P><P><S><C><R><Y><K><P><T><C><S><A><Y><M><L><T><A><I><E><K><H><G><T><K><G><I><L><M><G><I><A><R><I><L><R><C><H><P><F><V><A><G><G><V><D><P><V><P><E><D><F><S><L><M><R><N><K><N><T><S><K><N><A><E><K><A> | Could be involved in insertion of integral membrane proteins into the membrane.<BOP> | Q1JDC8 |
A9ADI4 | RL7_BURM1 | 50S ribosomal protein L7/L12 | Burkholderia cepacia complex | <M><A><I><A><K><E><D><I><L><A><A><V><E><G><M><T><V><L><E><L><N><E><L><V><K><A><F><E><E><K><F><G><V><S><A><A><A><V><A><V><A><G><P><A><G><G><G><A><A><A><A><A><E><E><K><T><D><F><T><V><V><L><A><E><A><G><S><N><K><V><A><V><I><K><A><V><R><E><I><T><G><L><G><L><K><E><A><K><D><L><V><D><G><A><P><K><P><V><K><E><G><V><D><K><A><A><A... | Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation.<BOP> | A9ADI4 |
C3MB73 | AROE_SINFN | Shikimate dehydrogenase (NADP(+)) | Sinorhizobium | <M><R><D><S><R><E><T><F><V><N><H><A><F><V><T><G><Y><P><I><K><H><S><R><S><P><L><I><H><G><Y><W><L><K><Q><F><G><I><A><G><S><Y><R><A><H><E><V><T><P><E><A><F><P><E><F><M><G><Q><L><R><D><G><G><T><G><F><C><G><G><N><V><T><I><P><H><K><E><M><A><F><E><L><S><D><R><P><D><E><L><S><A><E><L><G><A><A><N><T><L><W><L><E><D><G><R><I><C><A... | Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).<BOP> | C3MB73 |
P0CI69 | LPMG_SALT1 | Regulatory leader peptide for mgtA | Salmonella | <M><D><P><E><P><T><P><L><P><R><W><R><I><F><L><F><R> | Makes mgtA transcription sensitive to intracellular proline levels. At low levels of proline this proline-rich protein cannot be fully translated, and stem loop 'C' forms in the mgtA 5' UTR which permits transcription of the downstream mgtA gene. Osmotic shock induction (0.3 M NaCl) also depends on mgtL translation. Th... | P0CI69 |
A8YZP8 | HCHA_STAAT | Maillard deglycase | Staphylococcus | <M><S><Q><D><V><N><E><L><S><K><Q><P><T><P><D><K><A><E><D><N><A><F><F><P><S><P><Y><S><L><S><Q><Y><T><A><P><K><T><D><F><D><G><V><E><H><K><G><A><Y><K><D><G><K><W><K><V><L><M><I><A><A><E><E><R><Y><V><L><L><E><N><G><K><M><F><S><T><G><N><H><P><V><E><M><L><L><P><L><H><H><L><M><E><A><G><F><D><V><D><V><A><T><L><S><G><Y><P><V><K... | Protein and nucleotide deglycase that catalyzes the deglycation of the Maillard adducts formed between amino groups of proteins or nucleotides and reactive carbonyl groups of glyoxals. Thus, functions as a protein deglycase that repairs methylglyoxal- and glyoxal-glycated proteins, and releases repaired proteins and la... | A8YZP8 |
P49019 | HCAR3_HUMAN | Nicotinic acid receptor 2 | Homo | <M><N><R><H><H><L><Q><D><H><F><L><E><I><D><K><K><N><C><C><V><F><R><D><D><F><I><A><K><V><L><P><P><V><L><G><L><E><F><I><F><G><L><L><G><N><G><L><A><L><W><I><F><C><F><H><L><K><S><W><K><S><S><R><I><F><L><F><N><L><A><V><A><D><F><L><L><I><I><C><L><P><F><V><M><D><Y><Y><V><R><R><S><D><W><K><F><G><D><I><P><C><R><L><V><L><F><M><F... | Receptor for 3-OH-octanoid acid mediates a negative feedback regulation of adipocyte lipolysis to counteract prolipolytic influences under conditions of physiological or pathological increases in beta-oxidation rates. Acts as a low affinity receptor for nicotinic acid. This pharmacological effect requires nicotinic aci... | P49019 |
Q43433 | VATB2_GOSHI | Vacuolar proton pump subunit B 2 | Gossypium | <G><R><I><F><N><G><S><G><K><P><I><D><N><G><P><P><I><L><P><E><A><Y><L><D><I><S><G><S><S><I><N><P><S><E><R><T><Y><P><E><E><M><I><Q><T><G><I><S><T><I><D><V><M><N><S><I><A><R><G><Q><K><I><P><F><F><S><A><A><G><L><P><H><N><E><I><A><A><Q><I><C><R><Q><A><G><L><V><K><R><L><E><K><A><G><D><L><L><E><D><G><E><E><D><N><F><A><I><V><F... | Non-catalytic subunit of the peripheral V1 complex of vacuolar ATPase. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells.<BOP> | Q43433 |
Q8R0Z5 | MFRN2_MOUSE | Solute carrier family 25 member 28 | Mus | <M><E><L><E><G><R><S><A><G><G><V><A><G><G><P><A><A><G><P><G><R><S><P><G><E><S><A><L><L><D><G><W><L><Q><R><G><V><G><R><G><A><G><G><G><E><A><G><A><Y><Q><P><P><V><R><L><D><P><E><S><G><P><E><Y><E><A><L><P><A><G><A><T><V><T><T><H><M><V><A><G><A><V><A><G><I><L><E><H><C><V><M><Y><P><I><D><C><V><K><T><R><M><Q><S><L><Q><P><D><P... | Mitochondrial iron transporter that mediates iron uptake. Probably required for heme synthesis of hemoproteins and Fe-S cluster assembly in non-erythroid cells.<BOP> | Q8R0Z5 |
Q9UJ78 | ZMYM5_HUMAN | Zinc finger protein 237 | Homo | <M><E><K><C><S><V><G><G><L><E><L><T><E><Q><T><P><A><L><L><G><N><M><A><M><A><T><S><L><M><D><I><G><D><S><F><G><H><P><A><C><P><L><V><S><R><S><R><N><S><P><V><E><D><D><D><D><D><D><D><V><V><F><I><E><S><I><Q><P><P><S><I><S><A><P><A><I><A><D><Q><R><N><F><I><F><A><S><S><K><N><E><K><P><Q><G><N><Y><S><V><I><P><P><S><S><R><D><L><A... | Functions as a transcriptional regulator.<BOP> | Q9UJ78 |
Q34321 | CYB_DASHA | Ubiquinol-cytochrome-c reductase complex cytochrome b subunit | Dasyurus | <M><I><N><M><R><K><T><H><P><L><M><K><I><I><N><H><S><F><I><D><L><P><T><P><S><N><I><S><A><W><W><N><F><G><S><L><L><G><M><C><L><I><I><Q><I><L><T><G><L><F><L><A><M><H><Y><T><S><D><T><L><T><A><F><S><S><V><A><H><I><C><R><D><V><N><H><G><W><L><L><R><N><L><H><A><N><G><A><S><M><F><F><M><C><L><F><L><H><V><G><R><G><I><Y><Y><G><S><Y... | Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain. The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c. Contributes to the generation of a proton gradient across the mitochondrial membrane that is... | Q34321 |
B3R6G6 | DNAJ_CUPTR | Chaperone protein DnaJ | Cupriavidus | <M><A><K><R><D><Y><Y><E><V><L><G><V><G><K><N><A><S><D><D><E><I><K><K><A><Y><R><K><L><A><M><K><F><H><P><D><R><N><P><D><S><K><D><A><E><E><K><F><K><E><A><K><E><A><Y><E><M><L><S><D><P><E><K><K><A><A><Y><D><Q><Y><G><H><A><G><V><D><P><N><M><A><G><G><F><G><G><A><Q><G><Y><G><G><F><A><E><A><F><G><D><I><F><G><D><I><F><G><Q><G><G... | Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bou... | B3R6G6 |
B4NYT3 | DRE2_DROYA | Fe-S cluster assembly protein DRE2 homolog | Sophophora | <M><E><N><F><K><G><L><Q><K><S><L><Y><I><W><T><D><S><A><D><L><D><K><R><V><Q><Q><L><K><S><A><T><G><G><D><V><A><L><E><N><V><H><R><L><S><F><S><S><Y><A><N><S><S><F><D><L><I><V><I><E><C><A><Q><L><T><D><S><Y><V><K><L><L><H><M><L><K><P><S><G><K><L><H><L><V><S><F><I><G><P><A><A><S><L><L><Q><E><I><K><L><S><G><F><I><N><C><R><E><D... | Component of the cytosolic iron-sulfur (Fe-S) protein assembly (CIA) machinery. Required for the maturation of extramitochondrial Fe-S proteins. Part of an electron transfer chain functioning in an early step of cytosolic Fe-S biogenesis, facilitating the de novo assembly of a [4Fe-4S] cluster on the cytosolic Fe-S sca... | B4NYT3 |
A1AXD1 | RL19_RUTMC | 50S ribosomal protein L19 | Candidatus Ruthia | <M><N><L><I><D><Q><I><E><S><E><Q><L><K><L><D><L><P><S><F><S><S><G><D><T><I><V><V><Q><V><K><V><R><E><G><E><R><E><R><L><Q><A><F><E><G><V><V><I><A><K><K><N><R><G><I><G><S><A><F><T><V><R><K><I><S><H><G><E><G><I><E><R><V><F><Q><T><H><S><K><M><I><D><S><I><E><V><K><R><H><G><K><V><R><Q><A><K><L><Y><Y><L><R><S><L><T><G><K><K><A... | This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.<BOP> | A1AXD1 |
B8CH33 | HSLO_SHEPW | Heat shock protein 33 homolog | Shewanella | <M><T><K><D><N><L><Y><R><Y><L><F><D><N><A><S><V><R><G><E><L><V><Q><L><E><K><S><Y><Q><E><V><I><A><A><H><D><Y><P><V><A><I><Q><H><L><L><G><E><L><M><A><A><T><S><L><L><T><A><T><L><K><F><S><G><D><I><S><I><Q><L><Q><G><D><G><P><V><S><L><A><V><I><N><G><N><N><L><Q><Q><L><R><G><V><S><R><W><D><G><D><I><A><A><D><A><Q><L><Q><S><L><F... | Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress.<BOP> | B8CH33 |
A3PGM1 | RL14_CERS1 | 50S ribosomal protein L14 | Cereibacter | <M><I><Q><M><Q><T><N><L><D><V><A><D><N><S><G><A><R><R><V><Q><C><I><K><V><L><G><G><S><H><R><R><Y><A><S><V><G><D><I><I><V><V><S><V><K><E><A><I><P><R><G><R><V><K><K><G><D><V><R><K><A><V><V><V><R><T><A><K><E><V><R><R><E><D><G><T><T><I><R><F><D><R><N><A><A><V><I><L><N><N><Q><G><E><P><V><G><T><R><I><F><G><P><V><V><R><E><L><R... | Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.<BOP> | A3PGM1 |
Q88BX8 | GLMS_PSEPK | L-glutamine--D-fructose-6-phosphate amidotransferase | Pseudomonas | <M><C><G><I><V><G><A><V><A><E><R><N><I><T><A><I><L><I><E><G><L><K><R><L><E><Y><R><G><Y><D><S><A><G><L><A><V><L><T><Q><N><G><E><L><Q><R><R><R><R><I><G><K><V><S><E><L><E><V><A><V><A><D><D><P><L><A><G><Q><L><G><I><A><H><T><R><W><A><T><H><G><A><P><T><E><G><N><A><H><P><H><F><S><G><N><D><V><A><V><V><H><N><G><I><I><E><N><H><E... | Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.<BOP> | Q88BX8 |
Q9K0K4 | TRMD_NEIMB | tRNA [GM37] methyltransferase | Neisseria | <M><L><I><Q><A><V><T><I><F><P><E><M><F><D><S><I><T><R><Y><G><V><T><G><R><A><N><R><Q><G><I><W><Q><F><E><A><V><N><P><R><K><F><A><D><N><R><L><G><Y><I><D><D><R><P><F><G><G><G><P><G><M><I><M><M><A><P><P><L><H><A><A><I><E><H><A><K><T><Q><S><S><Q><A><A><K><V><I><Y><L><S><P><Q><G><K><P><L><T><H><Q><K><A><V><E><L><A><E><L><P><H... | Specifically methylates guanosine-37 in various tRNAs.<BOP> | Q9K0K4 |
C1IC47 | 3S13_WALAE | Three-finger toxin W-III | Walterinnesia | <M><K><T><L><L><L><T><L><V><V><V><T><I><V><C><L><D><L><G><H><T><F><V><C><H><N><Q><Q><S><S><Q><P><P><T><T><T><N><C><S><G><G><E><N><K><C><Y><K><K><Q><W><S><D><H><R><G><S><I><T><E><R><G><C><G><C><P><T><V><K><K><G><I><K><L><H><C><C><T><T><E><K><C><N><N> | Binds to muscle nicotinic acetylcholine receptor (nAChR) and inhibit acetylcholine from binding to the receptor, thereby impairing neuromuscular transmission.<BOP> | C1IC47 |
P0CL74 | DNLI_PYRAY | Polydeoxyribonucleotide synthase [ATP] | Pyrococcus | <M><R><Y><I><E><L><A><Q><L><Y><Q><K><L><E><K><T><T><M><K><L><I><K><T><R><L><V><A><D><F><L><K><K><V><P><E><D><H><L><E><F><I><P><Y><L><I><L><G><D><V><F><P><E><W><D><E><R><E><L><G><V><G><E><K><L><L><I><K><A><V><S><M><A><T><G><I><D><S><K><E><I><E><N><S><V><K><D><T><G><D><L><G><E><S><I><A><L><A><V><K><R><R><K><Q><K><S><F><F... | DNA ligase that seals nicks in double-stranded DNA during DNA replication, DNA recombination and DNA repair.<BOP> | P0CL74 |
Q9PFB8 | MUTL_XYLFA | DNA mismatch repair protein MutL | Xylella | <M><P><I><R><Q><L><P><E><I><L><I><N><Q><I><A><A><G><E><V><V><Q><R><P><A><S><V><V><K><E><L><V><E><N><A><I><D><A><G><A><T><R><V><D><I><E><L><E><A><A><G><G><R><L><I><R><I><R><D><N><G><H><G><M><A><A><Q><E><L><P><L><A><V><L><R><H><A><T><S><K><I><A><S><L><D><D><L><E><A><V><A><T><L><G><F><R><G><E><A><L><P><S><I><V><S><V><S><R... | This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part ... | Q9PFB8 |
B7MDB8 | COBS_ECO45 | Cobalamin-5'-phosphate synthase | Escherichia | <M><S><K><L><F><W><A><M><L><S><F><I><T><R><L><P><V><P><R><R><W><S><Q><G><L><D><F><E><H><Y><S><R><G><I><I><T><F><P><L><I><G><L><L><L><G><A><I><S><G><L><V><F><M><V><L><Q><A><W><C><G><A><P><L><A><A><L><F><S><V><L><V><L><V><L><M><T><G><G><F><H><L><D><G><L><A><D><T><C><D><G><V><F><S><A><R><S><R><D><R><M><L><E><I><M><R><D><S... | Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate.<BOP> | B7MDB8 |
A8FQ83 | LEU1_SHESH | Alpha-isopropylmalate synthase | Shewanella | <M><S><N><R><V><I><I><F><D><T><T><L><R><D><G><E><Q><A><L><A><A><S><L><T><V><K><E><K><L><Q><I><A><L><S><L><E><R><L><G><V><D><V><M><E><V><G><F><P><V><S><S><P><G><D><F><N><S><V><Q><T><I><A><N><T><V><K><N><S><R><V><C><A><L><A><R><A><L><E><K><D><I><D><A><A><A><Q><S><L><S><V><A><D><Q><F><R><I><H><T><F><I><S><T><S><T><I><H><V... | Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate).<BOP> | A8FQ83 |
Q7NM37 | GLGA_GLOVI | Starch [bacterial glycogen] synthase | Gloeobacter | <M><K><V><L><F><A><A><A><E><C><A><P><L><A><K><V><G><G><M><A><D><V><V><G><S><L><P><L><A><L><A><E><M><G><L><D><V><R><I><I><L><P><Y><Y><G><F><L><G><E><L><P><K><S><E><Q><P><V><W><T><G><G><A><M><F><Q><Q><V><E><I><Y><E><A><R><L><P><G><S><D><I><P><L><Y><L><V><G><H><P><A><F><A><N><E><R><I><Y><G><F><E><D><E><A><W><R><F><T><L><F... | Synthesizes alpha-1,4-glucan chains using ADP-glucose.<BOP> | Q7NM37 |
Q16AZ3 | DUT_ROSDO | dUTP pyrophosphatase | Roseobacter | <M><A><L><V><S><L><K><L><Q><W><A><D><G><A><D><T><S><V><P><L><P><A><Y><E><T><S><G><A><A><G><A><D><I><R><A><N><C><P><D><G><P><V><T><L><A><P><G><A><R><A><L><V><P><T><G><L><R><M><A><I><P><Q><G><Y><E><V><Q><I><R><P><R><S><G><L><A><L><R><H><G><I><T><L><V><N><S><P><G><T><I><D><S><D><Y><R><G><A><V><G><V><I><M><Q><N><L><G><D><A... | This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.<BOP> | Q16AZ3 |
Q8RNT4 | LOX_PSEAI | Oleate 10S-lipoxygenase | Pseudomonas | <M><K><R><R><S><V><L><L><S><G><V><A><L><S><G><T><A><L><A><N><D><S><I><F><F><S><P><L><K><Y><L><G><A><E><Q><Q><R><S><I><D><A><S><R><S><L><L><D><N><L><I><P><P><S><L><P><Q><Y><D><N><L><A><G><K><L><A><R><R><A><V><L><T><S><K><K><L><V><Y><V><W><T><E><N><F><A><N><V><K><G><V><P><M><A><R><S><V><P><L><G><E><L><P><N><V><D><W><L><L... | In presence of oxygen, converts linoleate into (9S)-hydroperoxy-10,12-octadecenoate (9HPOD), which spontaneously decomposes to the corresponding 9-hydroxy-10,12-octadecenoate (9HOD), and into 13-hydroperoxy-9,11-octadecenoate (13HPOD) which spontaneously decomposes to the corresponding 13-hydroxy-9,11-octadecenoate (13... | Q8RNT4 |
Q8DCA3 | METK_VIBVU | Methionine adenosyltransferase | Vibrio | <M><A><K><H><L><F><T><S><E><S><V><S><E><G><H><P><D><K><I><A><D><Q><I><S><D><A><V><L><D><A><I><L><E><Q><D><P><K><A><R><V><A><C><E><T><Y><V><K><T><G><M><V><M><V><G><G><E><I><T><T><S><A><W><V><D><I><E><E><L><T><R><E><T><V><R><E><I><G><Y><V><H><S><D><M><G><F><D><A><N><S><C><A><V><L><N><T><I><G><K><Q><S><P><D><I><N><Q><G><V... | Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.<BOP> | Q8DCA3 |
O47675 | COX2_NYCPR | Cytochrome c oxidase polypeptide II | Nyctereutes | <M><A><Y><P><F><Q><L><G><L><Q><D><A><T><S><P><I><M><E><E><L><L><H><F><H><D><H><T><L><M><I><V><F><L><I><S><S><L><V><L><Y><I><I><S><L><M><L><T><T><K><L><T><H><T><S><T><M><D><A><Q><E><V><E><T><V><W><T><I><L><P><A><I><I><L><I><L><I><A><L><L><S><L><R><I><L><Y><M><M><D><E><I><N><N><P><F><L><T><M><K><T><M><G><H><Q><W><Y><W><S... | Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CII... | O47675 |
A1W8D4 | RECR_ACISJ | Recombination protein RecR | unclassified Acidovorax | <M><S><D><T><S><S><L><D><A><L><I><Q><A><L><R><R><L><P><G><V><G><V><K><S><A><Q><R><M><A><F><H><L><L><Q><H><D><R><A><G><A><Q><V><L><S><Q><A><L><A><Q><A><A><T><Q><V><R><H><C><E><R><C><H><T><F><T><E><G><A><V><C><E><T><C><L><D><P><A><R><D><A><T><R><L><C><V><V><E><T><P><A><D><Q><A><A><M><E><R><T><A><A><F><K><G><L><Y><F><V><L... | May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO.<BOP> | A1W8D4 |
Q5E968 | CATK_BOVIN | Cathepsin K | Bos | <M><W><G><L><T><V><L><L><L><P><V><V><S><F><A><L><Y><P><E><E><I><L><D><T><Q><W><E><L><W><K><K><T><Y><R><K><Q><Y><N><S><K><G><D><E><I><S><R><R><L><I><W><E><K><N><L><K><H><I><S><I><H><N><L><E><A><S><L><G><V><H><T><Y><E><L><A><M><N><H><L><G><D><M><T><S><E><E><V><V><Q><K><M><T><G><L><K><V><P><A><S><R><S><R><S><N><D><T><L><Y... | Thiol protease involved in osteoclastic bone resorption and may participate partially in the disorder of bone remodeling. Displays potent endoprotease activity against fibrinogen at acid pH. May play an important role in extracellular matrix degradation. Involved in the release of thyroid hormone thyroxine (T4) by limi... | Q5E968 |
Q9JU79 | LEU3_NEIMA | Beta-IPM dehydrogenase | Neisseria | <M><T><K><H><I><A><I><L><R><G><D><G><I><G><P><E><I><V><A><E><T><V><R><V><L><D><K><L><I><A><Q><G><L><D><V><G><Y><E><Y><A><P><L><G><G><E><A><Y><D><E><Y><G><H><P><Y><P><E><F><T><Q><N><L><C><R><K><A><D><A><V><L><L><G><A><V><G><S><P><Q><Y><D><N><L><D><R><P><L><R><P><E><R><G><L><L><A><I><R><K><D><L><N><L><F><A><N><L><R><P><A... | Catalyzes the oxidation of 3-carboxy-2-hydroxy-4-methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2-oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate.<BOP> | Q9JU79 |
Q9KRP7 | ALDC_VIBCH | Alpha-acetolactate decarboxylase | Vibrio | <M><N><P><L><L><S><A><H><C><S><C><S><Q><E><I><A><Q><Q><F><A><H><Y><Q><H><I><S><G><E><G><E><I><Y><Q><T><S><L><M><S><A><L><I><A><G><V><Y><E><G><A><T><T><I><A><Q><L><L><E><H><G><D><F><G><L><G><T><F><N><E><L><D><G><E><L><I><A><F><D><R><Q><V><F><Q><L><R><A><D><G><S><A><Q><P><A><H><P><E><Q><Q><T><P><F><A><V><F><T><F><F><K><A... | Converts acetolactate into acetoin.<BOP> | Q9KRP7 |
Q122H7 | SUCC_POLSJ | Succinyl-CoA synthetase subunit beta | unclassified Polaromonas | <M><K><I><H><E><Y><Q><G><K><E><I><L><R><N><F><G><V><P><V><P><R><G><I><P><A><F><T><V><Q><E><A><V><E><A><A><Q><K><L><G><G><P><V><W><V><V><K><A><Q><I><H><A><G><G><R><G><K><G><G><G><V><K><V><A><K><T><I><D><D><V><K><R><I><A><G><E><I><L><G><M><Q><L><K><T><H><Q><T><G><P><E><G><Q><K><V><R><R><L><Y><I><E><D><G><A><D><I><Q><K><E... | Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinat... | Q122H7 |
B3E4H5 | LPXA_TRIL1 | Acyl-[acyl-carrier-protein]--UDP-N-acetylglucosamine O-acyltransferase | Trichlorobacter | <M><S><I><H><A><S><A><I><V><H><P><S><A><Q><L><A><E><G><V><E><V><G><P><Y><A><I><I><E><E><H><A><I><I><G><K><G><T><S><I><G><A><H><A><V><I><G><K><W><T><E><L><G><E><N><N><Q><I><Y><H><M><A><S><V><G><A><A><P><Q><D><L><K><Y><K><G><E><E><C><W><T><R><L><G><N><G><N><V><I><R><E><F><A><T><I><H><R><G><T><V><T><G><H><A><E><T><V><M><G... | Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.<BOP> | B3E4H5 |
Q8LB17 | RBL15_ARATH | Rhomboid-like protein 15 | Arabidopsis | <M><R><P><N><I><V><T><E><A><G><V><Q><T><R><V><G><Q><W><W><N><A><I><P><F><L><T><S><S><V><V><V><V><C><G><V><I><Y><L><I><C><L><L><T><G><Y><D><T><F><Y><E><V><C><F><L><P><S><A><I><I><S><R><F><Q><V><Y><R><F><Y><T><A><I><I><F><H><G><S><L><L><H><V><L><F><N><M><M><A><L><V><P><M><G><S><E><L><E><R><I><M><G><S><V><R><L><L><Y><L><T... | Probable rhomboid-type serine protease that catalyzes intramembrane proteolysis. May function in senescence.<BOP> | Q8LB17 |
Q9XSM2 | TRYT_SHEEP | Tryptase-2 | Ovis | <M><L><H><L><L><A><L><A><L><L><L><S><L><V><S><A><A><P><A><P><G><Q><A><L><Q><R><S><G><I><I><G><G><K><E><A><P><G><S><R><W><P><W><Q><V><S><L><R><V><R><D><Q><Y><W><R><H><Q><C><G><G><S><L><I><H><P><Q><W><V><L><T><A><A><H><C><I><G><P><E><L><Q><E><P><S><D><F><R><V><Q><L><R><E><Q><H><L><Y><Y><Q><D><R><L><L><P><I><S><R><V><I><P... | Tryptase is the major neutral protease present in mast cells and is secreted upon the coupled activation-degranulation response of this cell type.<BOP> | Q9XSM2 |
A8ZV62 | RL22_DESOH | 50S ribosomal protein L22 | Desulfosudis | <M><E><Q><V><S><A><T><A><R><Y><L><R><I><G><P><Q><K><V><R><M><L><V><D><G><I><K><G><K><S><V><E><K><G><L><N><T><L><R><F><M><P><N><K><G><A><G><L><V><E><K><A><L><R><S><A><V><A><N><A><E><E><K><N><M><D><V><D><G><L><V><I><L><N><V><L><V><D><Q><G><P><T><L><K><R><F><R><P><R><A><R><G><R><A><T><R><I><L><K><R><T><S><H><I><T><V><V><L... | The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.<BOP> | A8ZV62 |
B7GW24 | RS13_ACIB3 | 30S ribosomal protein S13 | Acinetobacter calcoaceticus/baumannii complex | <M><A><R><I><A><G><V><N><I><P><D><N><K><H><A><V><I><S><L><T><Y><I><F><G><I><G><R><H><T><A><K><N><I><L><A><A><V><G><I><T><E><T><T><K><I><R><E><L><D><D><A><Q><L><D><A><I><R><A><E><V><A><K><V><P><T><E><G><D><L><R><R><E><I><S><M><N><I><K><R><L><M><D><L><G><C><Y><R><G><L><R><H><R><R><S><L><P><V><R><G><Q><R><T><K><T><N><A><R... | Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites.<... | B7GW24 |
A1U1R0 | LPXH_MARN8 | UDP-2,3-diacylglucosamine diphosphatase | Marinobacter | <M><T><T><L><F><I><S><D><L><H><L><E><E><S><R><P><D><I><T><G><A><F><L><T><F><L><R><D><K><A><L><G><V><E><R><L><Y><I><L><G><D><F><F><E><A><W><I><G><D><D><E><R><T><P><L><Q><E><Q><V><A><A><A><L><R><E><V><R><D><T><G><T><D><I><Y><L><M><H><G><N><R><D><F><L><I><G><E><D><F><C><A><R><A><G><A><I><L><L><D><D><P><T><V><V><D><L><Y><G... | Hydrolyzes the pyrophosphate bond of UDP-2,3-diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.<B... | A1U1R0 |
A7ZM51 | CLCB_ECO24 | Voltage-gated ClC-type chloride channel ClcB | Escherichia | <M><F><R><R><L><L><I><A><T><V><V><G><I><L><A><A><F><A><V><A><G><F><R><H><A><M><L><L><L><E><W><L><F><L><N><N><D><S><G><S><L><V><N><A><A><T><N><L><S><P><W><R><R><L><L><T><P><A><L><G><G><L><A><A><G><L><L><L><M><G><W><Q><K><F><T><Q><Q><R><P><H><A><P><T><D><Y><M><E><A><L><Q><T><D><G><Q><F><D><Y><A><A><S><L><V><K><S><L><A><S... | Probably acts as an electrical shunt for an outwardly-directed proton pump that is linked to amino acid decarboxylation, as part of the extreme acid resistance (XAR) response.<BOP> | A7ZM51 |
Q09FZ7 | CCSA_PLAOC | Cytochrome c biogenesis protein CcsA | Platanus | <M><I><F><L><T><L><E><H><I><F><T><H><I><S><F><S><I><V><S><I><V><I><T><I><H><L><M><T><L><L><V><D><G><I><V><G><L><Y><D><S><S><E><K><G><M><I><A><T><F><L><C><I><T><G><F><L><V><T><R><W><I><Y><S><R><H><F><P><L><S><D><L><Y><E><S><L><I><F><L><S><W><S><F><S><I><I><H><M><V><P><K><I><R><N><H><K><N><H><L><S><A><I><T><A><P><S><A><I... | Required during biogenesis of c-type cytochromes (cytochrome c6 and cytochrome f) at the step of heme attachment.<BOP> | Q09FZ7 |
Q9FFZ6 | RBP11_ARATH | Small RNA-binding protein 11, chloroplastic | Arabidopsis | <M><A><A><L><A><R><I><G><G><R><H><L><K><S><V><C><L><I><N><S><S><A><S><C><F><F><T><Q><R><R><G><V><A><S><K><L><F><I><G><G><L><S><F><C><T><T><E><Q><G><L><S><E><A><F><S><K><C><G><Q><V><V><E><A><Q><I><V><M><D><R><V><S><D><R><S><K><G><F><G><F><V><T><F><A><S><A><D><E><A><Q><K><A><L><M><E><F><N><G><Q><Q><L><N><G><R><T><I><F><V... | Probable RNA-binding protein that may be involved in salt and oxidative stress tolerance.<BOP> | Q9FFZ6 |
B5XZS9 | CRCB_KLEP3 | Putative fluoride ion transporter CrcB | Klebsiella | <M><F><Q><L><L><C><A><V><F><I><G><G><G><T><G><S><V><L><R><W><W><L><G><M><K><L><N><P><V><H><H><A><I><P><I><G><T><L><T><A><N><L><V><G><A><F><V><I><G><A><G><L><A><W><F><N><R><L><T><D><I><D><P><M><W><K><L><L><I><T><T><G><F><C><G><G><L><T><T><F><S><T><F><S><A><E><V><V><F><L><L><Q><Q><G><R><V><S><W><A><L><L><N><V><M><V><N><L... | Important for reducing fluoride concentration in the cell, thus reducing its toxicity.<BOP> | B5XZS9 |
C8Z7U0 | YFH7_YEAS8 | Altered inheritance of mitochondria protein 12 | Saccharomyces | <M><V><D><T><H><K><L><A><D><D><V><L><H><L><L><D><N><R><I><E><D><N><Y><R><V><C><V><I><L><V><G><S><P><G><S><G><K><S><T><I><A><E><E><L><C><Q><I><I><N><E><K><Y><H><T><F><L><S><E><H><P><N><V><I><E><V><N><D><R><L><K><P><M><V><N><L><V><D><S><L><K><T><L><Q><P><N><E><V><A><E><M><I><E><N><Q><G><L><F><K><D><H><V><E><D><V><N><F><Q... | ATP-dependent kinase that could be involved in endoplasmic reticulum membrane assembly.<BOP> | C8Z7U0 |
Q1MJ02 | KGUA_RHIL3 | GMP kinase | Rhizobium | <M><K><P><A><K><S><S><P><V><Q><I><A><R><R><G><L><M><L><V><I><S><S><P><S><G><A><G><K><S><T><I><A><R><T><L><L><E><T><D><R><Q><I><G><L><S><V><S><V><T><T><R><Q><R><R><P><S><E><V><E><D><V><H><Y><H><F><K><S><V><R><E><F><E><R><L><R><D><S><D><A><L><L><E><W><A><E><V><H><G><N><F><Y><G><T><P><R><E><P><V><E><Q><A><M><G><E><G><R><D... | Essential for recycling GMP and indirectly, cGMP.<BOP> | Q1MJ02 |
A0QIQ3 | LEXA_MYCA1 | LexA repressor | Mycobacterium avium complex (MAC) | <M><D><D><S><N><D><S><S><S><A><G><P><D><G><R><L><H><A><V><D><P><S><L><T><E><R><Q><R><T><I><L><N><V><I><R><A><S><V><T><S><R><G><Y><P><P><S><I><R><E><I><G><D><A><V><G><L><T><S><T><S><S><V><A><H><Q><L><R><T><L><E><R><K><G><Y><L><R><R><D><P><N><R><P><R><A><V><D><V><R><G><V><D><D><D><V><A><A><P><A><T><E><V><A><G><S><D><A><L... | Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair... | A0QIQ3 |
P83299 | CAH1_CHIHA | Ice-CA | Chionodraco | <A><H><A><W><G><Y><G><P><T><D><G><P><D><K><W><V><S><N><F><P><I><A><D><G><P><R><Q><S><P><I><D><I><L><P><G><G><A><S><Y><D><S><G><L><K><P><L><S><L><K><Y><D><P><S><N><C><L><E><I><L><N><N><G><H><S><F><Q><V><T><F><A><D><D><S><D><S><S><T><L><K><E><G><P><I><S><G><V><Y><R><L><K><Q><F><H><F><H><W><G><A><S><N><D><K><G><S><E><H><T... | Catalyzes the reversible hydration of carbon dioxide.<BOP> | P83299 |
Q65TP2 | EX7S_MANSM | Exodeoxyribonuclease VII small subunit | Basfia | <M><A><R><K><P><K><E><S><S><T><V><D><F><E><T><T><L><N><Q><L><E><T><I><V><T><R><L><E><A><G><D><L><P><L><E><E><A><L><K><E><F><E><N><G><I><K><L><A><K><L><G><Q><E><R><L><Q><Q><A><E><Q><R><I><Q><I><L><L><Q><K><S><D><T><A><E><L><T><D><Y><Q><P><T><D><E> | Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.<BOP> | Q65TP2 |
Q9JXI5 | GMHBB_NEIMB | D,D-heptose 1,7-bisphosphate phosphatase | Neisseria | <M><K><L><I><I><L><D><R><D><G><V><I><N><Q><D><R><D><D><F><V><K><S><V><D><E><W><I><P><V><E><G><S><M><D><A><V><A><F><L><T><Q><A><G><Y><T><V><A><V><A><T><N><Q><S><G><I><G><R><K><Y><F><T><V><Q><N><L><T><E><M><H><A><K><M><H><R><L><V><R><Q><A><G><G><E><I><N><G><I><W><F><C><P><H><T><D><A><D><N><C><N><C><R><K><P><K><P><G><M><I... | Converts the D-glycero-beta-D-manno-heptose 1,7-bisphosphate intermediate into D-glycero-beta-D-manno-heptose 1-phosphate by removing the phosphate group at the C-7 position.<BOP> | Q9JXI5 |
Q8YEA6 | LNT_BRUME | Apolipoprotein N-acyltransferase | Brucella | <M><I><A><R><L><A><G><R><I><I><L><L><N><G><W><R><R><A><L><A><A><F><L><S><G><A><F><A><T><L><T><Q><P><P><F><D><I><F><V><A><G><F><V><S><F><P><V><L><V><W><L><I><D><G><A><I><A><R><T><D><A><G><P><L><R><R><L><L><L><A><A><K><V><G><W><W><F><G><F><G><Y><F><V><S><G><L><W><W><I><G><T><A><L><L><V><D><A><D><Q><F><A><W><A><L><P><L><A... | Catalyzes the phospholipid dependent N-acylation of the N-terminal cysteine of apolipoprotein, the last step in lipoprotein maturation.<BOP> | Q8YEA6 |
Q11QA9 | RS7_CYTH3 | 30S ribosomal protein S7 | Cytophaga | <M><R><K><A><K><P><K><K><R><Y><L><L><P><D><P><K><F><S><D><T><M><V><T><K><F><V><N><S><L><M><Y><D><G><K><K><S><T><A><Y><S><I><F><Y><D><A><V><A><L><V><E><K><K><T><S><E><S><G><L><E><V><W><K><K><A><L><N><N><V><S><P><Q><V><E><V><R><S><R><R><V><G><G><S><T><F><Q><V><P><T><E><V><R><P><D><R><K><M><A><L><G><M><K><W><L><I><N><Y><A... | One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.<BOP> | Q11QA9 |
F4JZT3 | ARR24_ARATH | Arabidopsis response regulator 24 | Arabidopsis | <M><T><R><D><Q><V><A><E><E><L><P><N><L><A><E><S><K><L><T><A><L><V><V><D><D><S><F><V><N><Q><T><I><H><Q><K><L><L><N><R><L><G><I><K><N><D><V><V><T><N><G><K><E><A><V><D><V><Y><C><S><G><G><N><Y><D><L><I><L><M><D><M><D><M><P><I><M><N><G><I><Q><A><T><K><R><L><R><E><M><G><I><E><S><K><I><A><G><V><T><T><R><A><N><E><G><E><K><K><E... | Functions as response regulator involved in His-to-Asp phosphorelay signal transduction system. Phosphorylation of the Asp residue in the receiver domain activates the ability of the protein to promote the transcription of target genes. Type-A response regulators seem to act as negative regulators of the cytokinin sign... | F4JZT3 |
Q9CAU4 | SCP4_ARATH | Serine carboxypeptidase-like 4 | Arabidopsis | <M><A><N><N><N><V><Y><S><V><L><K><S><L><L><L><L><L><H><L><V><F><L><S><K><Q><H><V><D><S><A><S><I><V><K><F><L><P><G><F><E><G><P><L><P><F><E><L><E><T><G><Y><I><G><V><G><E><E><E><E><V><Q><L><F><Y><Y><F><I><K><S><E><R><N><P><K><E><D><P><L><L><L><W><L><T><G><G><P><G><C><S><A><I><S><G><L><L><Y><Q><N><G><P><L><A><M><K><L><D><V... | Probable carboxypeptidase.<BOP> | Q9CAU4 |
Q3SZX2 | IPP2_BOVIN | Protein phosphatase inhibitor 2 | Bos | <M><A><A><S><T><A><S><H><R><P><I><K><G><I><L><K><N><K><S><S><T><T><S><S><V><V><S><T><A><E><Q><P><G><K><S><V><D><E><E><L><S><K><K><S><Q><K><W><D><E><M><S><I><L><A><T><Y><H><P><A><D><K><D><Y><G><L><M><K><I><D><E><P><S><T><P><Y><H><S><M><V><A><D><D><E><D><A><L><S><D><S><E><T><T><E><A><L><T><P><D><I><L><A><R><K><L><T><A><A... | Inhibitor of protein-phosphatase 1.<BOP> | Q3SZX2 |
Q8IQ56 | TMM11_DROME | Protein PMI | Sophophora | <M><V><S><R><N><I><E><S><T><S><K><V><P><T><F><H><V><I><R><E><V><Y><D><S><S><N><A><H><E><R><F><E><A><E><L><D><K><A><L><E><A><K><L><D><F><I><V><I><E><P><P><R><L><G><D><E><T><G><R><W><I><W><V><G><N><C><L><H><K><T><A><V><A><T><G><V><V><S><L><V><A><S><L><L><W><R><D><R><P><I><I><A><A><P><A><C><A><L><S><I><F><C><T><G><L><Y><T... | Plays a role in mitochondrial morphogenesis.<BOP> | Q8IQ56 |
C6E9F3 | ATPA_GEOSM | F-ATPase subunit alpha | unclassified Geobacter | <M><E><I><K><A><E><E><I><S><E><I><I><R><K><Q><I><K><E><Y><G><T><E><V><A><V><A><E><T><G><T><I><I><S><I><G><D><G><I><A><R><I><H><G><L><D><K><A><M><A><G><E><L><L><E><F><P><G><G><I><T><G><M><V><L><N><L><E><E><D><N><V><G><A><A><I><L><G><E><F><S><E><I><K><E><G><D><S><V><K><L><T><G><K><I><V><E><V><P><V><G><P><A><L><I><G><R><V... | Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit.<BOP> | C6E9F3 |
A4JCM8 | PNCB_BURVG | Nicotinate phosphoribosyltransferase | Burkholderia cepacia complex | <M><I><I><T><S><L><L><D><T><D><L><Y><K><F><T><M><M><Q><V><V><L><H><H><F><P><A><A><T><V><E><Y><R><F><R><C><R><T><R><G><V><D><L><V><P><Y><I><D><E><I><R><D><E><V><R><G><L><C><A><L><R><F><T><D><V><E><L><D><Y><L><R><R><M><R><F><I><K><S><D><F><V><D><F><L><A><L><F><H><L><N><E><K><Y><I><S><I><M><P><S><P><K><G><N><G><E><I><D><I... | Catalyzes the synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP.<BOP> | A4JCM8 |
A9ILI4 | ARGB_BART1 | NAG kinase | Bartonella | <M><D><D><A><K><N><S><A><V><D><V><L><E><K><Q><A><A><F><L><S><S><A><L><P><Y><M><Q><K><Y><E><N><E><T><V><V><V><K><Y><G><G><H><A><M><G><D><P><A><L><G><R><A><F><A><R><D><I><A><L><L><K><Q><S><G><I><N><P><V><V><V><H><G><G><G><P><Q><I><A><E><I><L><M><K><M><G><I><E><S><R><F><E><N><G><L><R><V><T><D><E><R><I><V><E><V><V><E><M><V... | Catalyzes the ATP-dependent phosphorylation of N-acetyl-L-glutamate.<BOP> | A9ILI4 |
Q0VL18 | PSTB_ALCBS | Phosphate-transporting ATPase | Alcanivorax | <M><E><T><A><Q><Q><L><D><K><P><A><L><D><T><N><D><A><A><R><D><K><A><I><N><E><Q><V><T><M><T><Q><D><T><P><Y><P><D><Q><T><V><G><N><P><F><V><D><D><P><K><M><R><L><R><D><V><E><V><F><Y><D><D><N><Q><A><I><H><G><V><S><L><D><I><G><K><N><E><V><V><S><L><I><G><P><S><G><C><G><K><S><T><F><L><R><C><L><N><R><M><N><D><T><I><D><I><C><K><V... | Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system.<BOP> | Q0VL18 |
P32236 | GNRHR_BOVIN | Gonadotropin-releasing hormone receptor | Bos | <M><A><N><S><D><S><P><E><Q><N><E><N><H><C><S><A><I><N><S><S><I><P><L><T><P><G><S><L><P><T><L><T><L><S><G><K><I><R><V><T><V><T><F><F><L><F><L><L><S><T><I><F><N><T><S><F><L><L><K><L><Q><N><W><T><Q><R><K><E><K><R><K><K><L><S><R><M><K><L><L><L><K><H><L><T><L><A><N><L><L><E><T><L><I><V><M><P><L><D><G><M><W><N><I><T><V><Q><W... | Receptor for gonadotropin releasing hormone (GnRH) that mediates the action of GnRH to stimulate the secretion of the gonadotropic hormones luteinizing hormone (LH) and follicle-stimulating hormone (FSH). This receptor mediates its action by association with G-proteins that activate a phosphatidylinositol-calcium secon... | P32236 |
P29428 | SODC2_PICAB | Superoxide dismutase [Cu-Zn] II | Picea | <M><S><P><L><K><A><V><A><V><L><T><G><A><D><V><K><G><V><V><Q><F><T> | Destroys radicals which are normally produced within the cells and which are toxic to biological systems.<BOP> | P29428 |
Q46244 | ANFG_CLOPA | Nitrogenase component I | Clostridium | <M><E><D><P><S><K><V><Q><L><N><Q><L><T><D><Y><I><M><K><N><C><L><W><Q><F><H><S><R><K><W><D><R><E><R><Q><N><E><G><I><L><T><K><T><K><Q><I><L><L><G><E><E><V><D><L><S><T><P><A><D><R><C><Y><Y><A><D><A><L><C><L><A><D><A><Y><K><T><E><Y><P><W><I><N><D><M><S><K><D><E><L><I><Q><L><M><Q><Q><L><K><D><R><I><D><Y><V><T><I><T><G><S><L... | The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex, which has 2 components: the iron protein (component 2) and a component 1 which is either a molybdenum-iron protein, a vanadium-iron, or an iron-iron protein.<BOP> | Q46244 |
A4VK43 | TAL_PSEU5 | Transaldolase | Pseudomonas | <M><T><S><K><L><E><Q><L><K><Q><F><T><T><V><V><A><D><T><G><D><I><D><A><I><A><R><L><K><P><V><D><A><T><T><N><P><S><L><L><L><K><A><A><A><M><P><R><Y><A><E><H><L><G><N><A><M><K><Q><C><Q><G><D><I><G><L><A><C><D><L><F><A><V><A><V><G><K><Q><I><L><E><L><I><P><G><R><I><S><T><E><V><D><A><R><L><S><F><D><T><Q><A><M><V><Q><R><G><E><R... | Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.<BOP> | A4VK43 |
B4S3W8 | RISB_PROA2 | 6,7-dimethyl-8-ribityllumazine synthase | Prosthecochloris | <M><T><I><K><T><I><E><G><T><L><D><A><R><N><S><R><F><A><L><V><V><S><R><F><N><D><F><I><G><Q><K><L><V><E><G><A><V><D><C><I><V><R><H><G><G><S><E><E><Q><I><A><L><Y><K><C><P><G><A><F><E><L><P><S><V><A><K><K><V><A><V><S><G><R><Y><D><A><V><I><T><L><G><A><I><I><R><G><A><T><S><H><Y><D><V><I><A><A><E><A><T><K><G><V><A><Q><V><G><L... | Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.<BOP> | B4S3W8 |
Q2NS03 | UNG_SODGM | Uracil-DNA glycosylase | Sodalis | <M><T><Q><M><L><T><W><R><D><A><L><A><Q><E><K><T><L><P><Y><F><Q><E><T><L><A><F><V><A><R><E><R><A><A><G><M><T><V><Y><P><P><A><K><D><V><F><N><A><F><R><F><T><E><L><N><A><V><K><V><V><I><L><G><Q><D><P><Y><H><G><P><N><Q><A><H><G><L><S><F><S><V><K><P><G><V><P><A><P><P><S><L><V><N><I><Y><K><E><L><A><S><D><I><P><G><F><V><I><P><N... | Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.<BOP> | Q2NS03 |
Q7VNA7 | PSD_HAEDU | Phosphatidylserine decarboxylase beta chain | Haemophilus | <M><S><L><K><S><Y><S><T><P><T><Y><W><Q><R><V><K><V><A><C><Q><Y><L><F><P><Q><L><P><I><T><R><L><A><G><W><L><A><E><Q><K><W><G><M><V><T><H><F><I><I><R><I><F><A><K><Q><Y><N><V><N><L><A><E><A><E><K><T><N><P><A><D><Y><T><T><F><N><E><F><F><L><R><P><L><K><E><N><A><R><P><I><N><Q><D><D><Q><A><V><C><L><P><A><D><G><K><I><S><E><L><G... | Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer).<BOP> | Q7VNA7 |
A7N0H8 | RPOA_VIBC1 | Transcriptase subunit alpha | Vibrio | <M><Q><G><S><V><T><E><F><L><K><P><R><L><V><D><I><E><Q><I><S><S><T><H><A><K><V><T><L><E><P><L><E><R><G><F><G><H><T><L><G><N><A><L><R><R><I><L><L><S><S><M><P><G><C><A><V><I><E><V><E><I><E><G><V><L><H><E><Y><S><T><K><E><G><V><Q><E><D><I><L><E><I><L><L><N><L><K><G><L><A><V><R><V><A><E><G><K><D><E><V><F><I><T><L><N><K><S><G... | DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.<BOP> | A7N0H8 |
O15205 | UBD_HUMAN | Ubiquitin-like protein FAT10 | Homo | <M><A><P><N><A><S><C><L><C><V><H><V><R><S><E><E><W><D><L><M><T><F><D><A><N><P><Y><D><S><V><K><K><I><K><E><H><V><R><S><K><T><K><V><P><V><Q><D><Q><V><L><L><L><G><S><K><I><L><K><P><R><R><S><L><S><S><Y><G><I><D><K><E><K><T><I><H><L><T><L><K><V><V><K><P><S><D><E><E><L><P><L><F><L><V><E><S><G><D><E><A><K><R><H><L><L><Q><V><R... | Ubiquitin-like protein modifier which can be covalently attached to target protein and subsequently leads to their degradation by the 26S proteasome, in a NUB1-dependent manner. Probably functions as a survival factor. Conjugation ability activated by UBA6. Promotes the expression of the proteasome subunit beta type-9 ... | O15205 |
A3MWZ8 | RL24_PYRCJ | 50S ribosomal protein L24 | Pyrobaculum | <M><P><F><T><A><S><A><Q><P><R><K><Q><R><L><S><L><Y><A><A><P><L><H><L><R><R><K><L><L><N><A><K><L><S><P><E><L><Q><K><K><L><G><V><K><R><L><P><V><R><R><G><D><T><V><L><I><M><R><G><D><F><K><G><V><T><G><K><V><V><K><V><D><L><K><R><V><R><I><F><V><E><G><A><T><R><T><N><S><R><G><Q><T><V><Y><Y><P><I><H><P><S><K><V><M><I><V><D><V><D... | Located at the polypeptide exit tunnel on the outside of the subunit.<BOP> | A3MWZ8 |
Q7VAP4 | AMPA_PROMA | Leucyl aminopeptidase | Prochlorococcus | <M><Q><I><S><L><Y><Q><K><N><L><A><D><W><T><G><S><I><I><A><V><G><L><L><E><G><Q><I><Q><E><Q><L><S><L><L><E><E><I><C><D><Y><D><S><L><L><T><H><V><E><E><K><D><F><S><A><K><A><G><E><L><I><K><L><E><I><L><G><K><S><L><E><K><I><I><L><I><G><L><G><K><P><E><A><L><S><I><D><D><L><R><E><G><A><A><L><A><S><R><A><S><I><G><S><K><G><K><I><G... | Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides.<BOP> | Q7VAP4 |
Q2GJ82 | PDXH_ANAPZ | Pyridoxal 5'-phosphate synthase | phagocytophilum group | <M><T><I><N><K><E><G><L><R><V><D><A><C><S><G><D><P><M><S><I><F><G><L><W><Y><E><E><V><L><R><V><K><S><V><R><E><P><S><A><M><V><L><A><T><C><D><S><E><N><R><P><S><A><R><V><V><L><L><K><R><Y><S><D><A><G><F><E><F><Y><T><N><L><E><S><R><K><A><R><E><I><A><L><N><P><C><V><S><L><V><F><D><W><R><P><I><Y><K><Q><V><R><V><E><G><I><A><E><F... | Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP).<BOP> | Q2GJ82 |
Q8WVZ9 | KBTB7_HUMAN | Kelch repeat and BTB domain-containing protein 7 | Homo | <M><Q><S><R><E><D><V><P><R><S><R><R><L><A><S><P><R><G><G><R><R><P><K><R><I><S><K><P><S><V><S><A><F><F><T><G><P><E><E><L><K><D><T><A><H><S><A><A><L><L><A><Q><L><K><S><F><Y><D><A><R><L><L><C><D><V><T><I><E><V><V><T><P><G><S><G><P><G><T><G><R><L><F><S><C><N><R><N><V><L><A><A><A><C><P><Y><F><K><S><M><F><T><G><G><M><Y><E><S... | As part of the CUL3(KBTBD6/7) E3 ubiquitin ligase complex functions as a substrate adapter for the RAC1 guanine exchange factor (GEF) TIAM1, mediating its 'Lys-48' ubiquitination and proteasomal degradation . By controlling this ubiquitination, regulates RAC1 signal transduction and downstream biological processes incl... | Q8WVZ9 |
P10613 | CP51_CANAL | Sterol 14-alpha demethylase | Candida | <M><A><I><V><E><T><V><I><D><G><I><N><Y><F><L><S><L><S><V><T><Q><Q><I><S><I><L><L><G><V><P><F><V><Y><N><L><V><W><Q><Y><L><Y><S><L><R><K><D><R><A><P><L><V><F><Y><W><I><P><W><F><G><S><A><A><S><Y><G><Q><Q><P><Y><E><F><F><E><S><C><R><Q><K><Y><G><D><V><F><S><F><M><L><L><G><K><I><M><T><V><Y><L><G><P><K><G><H><E><F><V><F><N><A... | Lanosterol 14-alpha demethylase; part of the third module of ergosterol biosynthesis pathway that includes the late steps of the pathway . The lanosterol 14-alpha-demethylase ERG11 (also known as CYP51) catalyzes C14-demethylation of lanosterol to produce 4,4'-dimethyl cholesta-8,14,24-triene-3-beta-ol, which is critic... | P10613 |
Q56063 | PRPC_SALTY | Citrate synthase | Salmonella | <M><T><D><T><T><I><L><Q><N><N><T><H><V><I><K><P><K><K><S><V><A><L><S><G><V><P><A><G><N><T><A><L><C><T><V><G><K><S><G><N><D><L><H><Y><R><G><Y><D><I><L><D><L><A><E><H><C><E><F><E><E><V><A><H><L><L><I><H><G><K><L><P><T><R><D><E><L><N><A><Y><K><S><K><L><K><A><L><R><G><L><P><A><N><V><R><T><V><L><E><A><L><P><A><A><S><H><P><M... | Involved in the catabolism of short chain fatty acids (SCFA) via the tricarboxylic acid (TCA)(acetyl degradation route) and via the 2-methylcitrate cycle I (propionate degradation route). Catalyzes the Claisen condensation of propionyl-CoA and oxaloacetate (OAA) to yield 2-methylcitrate (2-MC) and CoA. Also catalyzes t... | Q56063 |
D4GZM5 | DACZ_HALVD | Cyclic-di-AMP synthase | Haloferax | <M><A><A><L><S><E><L><L><G><D><L><V><A><D><V><D><G><L><F><L><F><T><P><S><S><S><H><Y><E><Q><F><A><E><T><D><V><P><T><V><V><I><A><P><E><N><T><V><E><A><E><T><F><V><E><L><P><L><Q><F><Q><N><V><K><D><R><I><R><F><G><V><E><G><A><M><E><Q><S><I><V><E><A><G><D><T><I><A><C><N><V><G><T><F><G><G><D><P><D><S><L><V><R><V><R><V><E><E><N... | Diadenylate cyclase that catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c-di-AMP is a second messenger for intracellular signal transduction involved in the control of important regulatory processes such as osmoregulation. Is essential for H.volcanii. Overexpression of DacZ leads to cell d... | D4GZM5 |
B8ABC2 | LRR1_ORYSI | Leucine-rich repeat protein 1 | Oryza sativa | <M><G><A><G><A><L><G><V><V><A><M><V><A><A><A><V><V><V><A><M><A><G><A><N><S><E><G><D><A><L><S><A><L><R><R><S><L><R><D><P><G><G><V><L><Q><S><W><D><P><T><L><V><N><P><C><T><W><F><H><V><T><C><D><R><D><N><R><V><T><R><L><D><L><G><N><L><N><L><S><G><H><L><V><P><E><L><G><K><L><D><H><L><Q><Y><L><E><L><Y><K><N><N><I><Q><G><T><I><P... | Involved in plant defense response.<BOP> | B8ABC2 |
Q2SPF8 | HSLO_HAHCH | Heat shock protein 33 homolog | Hahella | <M><K><A><D><L><L><Q><R><F><I><F><D><E><L><D><I><R><G><E><L><L><V><L><K><K><T><V><Q><D><A><L><S><R><H><D><Y><P><Q><A><I><Q><S><L><L><G><Q><A><L><S><A><G><L><L><L><S><A><T><L><K><I><K><G><D><T><T><L><Q><A><T><G><E><G><E><L><R><L><L><M><A><E><A><T><H><R><R><T><A><R><G><I><A><R><W><E><G><A><P><D><S><T><S><L><K><Q><L><L><G... | Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress.<BOP> | Q2SPF8 |
A7MEB1 | CMOA_CROS8 | Carboxy-S-adenosyl-L-methionine synthase | Cronobacter | <M><S><N><R><D><T><L><F><S><A><P><I><A><R><L><G><D><W><T><F><D><E><R><V><A><E><V><F><P><D><M><I><Q><R><S><V><P><G><Y><S><N><I><I><S><M><I><G><M><L><A><E><R><F><V><Q><P><A><S><Q><V><Y><D><L><G><C><S><L><G><A><A><T><L><S><V><R><R><N><V><H><H><D><G><C><K><I><I><A><V><D><N><S><P><A><M><V><E><R><C><R><R><H><I><D><A><F><K><A... | Catalyzes the conversion of S-adenosyl-L-methionine (SAM) to carboxy-S-adenosyl-L-methionine (Cx-SAM).<BOP> | A7MEB1 |
Q083S7 | CDD_SHEFN | Cytidine aminohydrolase | Shewanella | <M><Q><N><R><F><L><E><S><I><T><Q><L><D><K><P><L><A><N><A><L><V><P><L><L><H><D><Q><F><C><G><H><I><D><A><S><Q><F><A><G><L><V><K><A><S><G><K><T><E><Q><Q><V><L><M><D><L><L><P><I><A><A><A><L><A><N><P><P><I><S><E><F><Y><V><G><A><I><A><K><G><S><S><G><D><L><Y><M><G><A><N><L><E><L><P><G><E><A><L><F><H><S><V><H><A><E><Q><S><A><I... | This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis.<BOP> | Q083S7 |
D4DB32 | UTP25_TRIVH | U three protein 25 | Trichophyton | <M><A><I><Q><H><K><K><G><G><G><H><R><G><R><G><S><K><T><G><R><S><R><G><R><K><F><E><T><S><R><L><K><D><V><R><E><D><E><S><S><G><G><E><E><D><V><D><G><Q><P><T><E><D><M><N><D><S><E><G><T><D><V><S><S><E><S><G><L><D><E><P><P><K><E><N><S><Y><S><T><L><L><K><L><L><N><T><D><A><K><S><N><E><P><A><R><K><K><R><K><I><K><A><N><E><P><D><A... | DEAD-box RNA helicase-like protein required for pre-18S rRNA processing, specifically at sites A0, A1, and A2.<BOP> | D4DB32 |
O08349 | MDH_ARCFU | Malate dehydrogenase | Archaeoglobus | <M><K><L><G><F><V><G><A><G><R><V><G><S><T><S><A><F><T><C><L><L><N><L><D><V><D><E><I><A><L><V><D><I><A><E><D><L><A><V><G><E><A><M><D><L><A><H><A><A><A><G><I><D><K><Y><P><K><I><V><G><G><A><D><Y><S><L><L><K><G><S><E><I><I><V><V><T><A><G><L><A><R><K><P><G><M><T><R><L><D><L><A><H><K><N><A><G><I><I><K><D><I><A><K><K><I><V><E... | Catalyzes the reversible oxidation of malate to oxaloacetate. Can also oxidize tartrate.<BOP> | O08349 |
B1A990 | NDHH_CARPA | NADH-plastoquinone oxidoreductase subunit H | Carica | <M><N><I><P><A><T><G><K><D><F><M><I><V><N><M><G><P><H><H><P><S><M><H><G><V><L><R><L><I><V><T><L><D><G><E><D><V><I><D><C><E><P><I><L><G><Y><L><H><R><G><M><E><K><I><A><E><N><R><T><I><I><Q><Y><L><P><Y><V><T><R><W><D><Y><L><A><T><M><F><T><E><A><I><T><V><N><G><P><E><Q><L><G><N><I><Q><V><P><K><R><A><S><Y><I><R><V><I><M><L><E... | NDH shuttles electrons from NAD(P)H:plastoquinone, via FMN and iron-sulfur (Fe-S) centers, to quinones in the photosynthetic chain and possibly in a chloroplast respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translo... | B1A990 |
A7HYC4 | SYDND_PARL1 | Non-discriminating aspartyl-tRNA synthetase | Parvibaculum | <M><S><S><F><R><S><H><T><S><G><E><L><R><K><S><H><V><G><E><T><V><R><L><A><G><W><V><H><R><K><R><D><H><G><G><L><L><F><I><D><L><R><D><N><Y><G><L><T><Q><L><V><F><D><P><D><R><A><E><A><F><A><L><A><E><K><L><R><A><E><Y><V><V><A><I><E><G><K><V><V><A><R><S><A><E><T><I><N><A><N><L><P><T><G><D><I><E><I><A><V><S><S><M><E><V><L><S><E... | Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn).<BOP> | A7HYC4 |
Q14213 | IL27B_HUMAN | Epstein-Barr virus-induced gene 3 protein | Homo | <M><T><P><Q><L><L><L><A><L><V><L><W><A><S><C><P><P><C><S><G><R><K><G><P><P><A><A><L><T><L><P><R><V><Q><C><R><A><S><R><Y><P><I><A><V><D><C><S><W><T><L><P><P><A><P><N><S><T><S><P><V><S><F><I><A><T><Y><R><L><G><M><A><A><R><G><H><S><W><P><C><L><Q><Q><T><P><T><S><T><S><C><T><I><T><D><V><Q><L><F><S><M><A><P><Y><V><L><N><V><T... | Associates with IL27 to form the IL-27 interleukin, a heterodimeric cytokine which functions in innate immunity. IL-27 has pro- and anti-inflammatory properties, that can regulate T-helper cell development, suppress T-cell proliferation, stimulate cytotoxic T-cell activity, induce isotype switching in B-cells, and that... | Q14213 |
A4FN28 | ATPG_SACEN | F-ATPase gamma subunit | Saccharopolyspora | <M><A><Q><L><R><E><L><R><N><R><I><R><S><V><K><S><T><R><K><I><T><K><A><Q><E><L><I><A><T><S><R><I><M><K><A><Q><A><R><V><E><A><S><R><P><Y><A><D><E><I><T><N><V><L><T><A><L><A><D><A><S><T><L><D><H><P><L><L><T><E><R><E><N><P><K><R><A><G><V><L><V><V><T><S><D><R><G><F><C><G><G><Y><N><A><N><V><L><R><A><A><E><E><L><Q><T><L><L><R... | Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.<BOP> | A4FN28 |
Q8TI26 | TBP1_METAC | TATA-box factor 1 | Methanosarcina | <M><S><E><S><S><I><K><I><E><N><V><V><A><S><T><K><L><A><E><E><F><D><L><T><V><I><E><S><E><F><E><G><A><E><Y><N><K><Q><K><F><P><G><L><V><Y><R><V><S><D><P><K><A><A><F><L><V><F><T><S><G><K><V><V><C><T><G><A><K><N><V><A><D><V><H><T><V><I><G><N><M><A><K><K><L><N><S><I><G><I><K><T><M><E><N><P><Q><I><T><V><Q><N><I><V><A><S><A><D... | General factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase. Binds specifically to the TATA box promoter element which lies close to the position of transcription initiation.<BOP> | Q8TI26 |
Q0C604 | YBEY_HYPNA | Endoribonuclease YbeY | Hyphomonas | <M><I><S><F><D><L><I><V><E><D><D><S><W><A><A><L><G><D><L><E><A><L><C><R><K><A><F><D><A><A><E><Y><V><A><P><V><E><E><G><N><I><A><L><L><L><A><D><N><H><V><L><H><Q><L><N><L><D><F><R><S><K><D><K><P><T><D><V><L><S><F><P><S><L><P><M><D><R><P><F><L><G><D><I><A><V><A><W><G><V><S><A><S><D><A><K><I><Q><G><K><P><L><D><A><H><L><V><H... | Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.<BOP> | Q0C604 |
Q2JS37 | PSBJ_SYNJA | Photosystem II reaction center protein J | unclassified Synechococcus | <M><T><S><Q><A><R><I><P><L><W><I><V><A><V><V><V><G><L><G><V><V><T><V><V><G><L><F><F><Y><G><S><Y><T><G><L><G><A><P><V> | One of the components of the core complex of photosystem II (PSII). PSII is a light-driven water:plastoquinone oxidoreductase that uses light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation. It consists of a core antenna complex that captures photons, a... | Q2JS37 |
B0TZ23 | SUCC_FRAP2 | Succinyl-CoA synthetase subunit beta | Francisella | <M><N><L><H><E><Y><Q><A><K><D><L><L><E><S><Y><G><L><K><V><Q><K><G><I><V><A><H><N><P><N><E><A><A><Q><A><F><D><Q><L><G><G><K><F><A><V><V><K><A><Q><V><H><A><G><G><R><G><K><A><G><G><V><K><V><V><K><S><S><Q><E><A><R><E><V><A><E><S><L><I><G><T><N><L><V><T><F><Q><T><D><A><E><G><Q><P><V><N><S><V><G><V><F><E><D><V><Y><P><V><T><R... | Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinat... | B0TZ23 |
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