accession stringlengths 6 10 | name stringlengths 6 11 | Full Name stringlengths 1 147 ⌀ | taxon stringlengths 3 46 ⌀ | sequence stringlengths 48 2.3k | function stringlengths 11 1.34k | AlphaFoldDB stringlengths 6 10 |
|---|---|---|---|---|---|---|
Q2YAI3 | APT_NITMU | Adenine phosphoribosyltransferase | Nitrosospira | <M><Q><I><K><S><R><I><R><T><I><A><H><Y><P><H><E><G><I><M><F><R><D><I><T><T><L><L><K><D><P><V><G><L><R><A><T><I><Q><E><I><A><S><R><Y><K><S><M><K><I><D><K><V><A><G><I><E><S><R><G><F><I><I><G><A><P><V><A><Y><E><L><G><V><G><F><V><P><V><R><K><K><G><K><L><P><A><E><T><R><G><R><D><Y><Q><L><E><Y><G><S><D><R><I><E><I><H><V><D><A... | Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.<BOP> | Q2YAI3 |
P85045 | LYS_BUFGA | 1,4-beta-N-acetylmuramidase C | Bufo | <S><G><K><Y><I><S><W><E><D><S><C><S><Y><L><Q><L><Q><K><Y><E><R><C><E><L><A><K><A><L><K><K><G><G><L><A><D><F><K><G><Y><S><L><E><N><W><I><C><T><A><F><H><E><S><G><Y><N><T><A><S><T><N><Y><N><P><P><D><K><S><T><D><Y><G><I><F><Q><I><N><S><R><W><W><C><N><D><Y><K><T><P><R><S><K><N><T><C><N><I><D><C><K><V><L><L><G><D><D><I><S><P... | Lysozymes have primarily a bacteriolytic function; those in tissues and body fluids are associated with the monocyte-macrophage system and enhance the activity of immunoagents. Has antibacterial activity against the Gram-positive bacterium S.aureus and against the Gram-negative bacterium E.coli with a MIC of 1 uM and 8... | P85045 |
Q0DHE3 | ZIP9_ORYSJ | ZRT/IRT-like protein 9 | Oryza sativa | <M><A><F><D><L><K><L><T><A><C><L><L><L><A><V><F><S><L><A><A><A><A><D><C><E><C><Q><P><S><D><E><G><H><D><A><A><K><S><R><T><L><K><V><I><A><I><F><C><I><L><V><G><S><S><A><G><C><A><I><P><S><L><G><R><R><F><P><A><L><R><P><D><T><S><L><F><F><A><L><K><A><F><A><A><G><V><I><L><A><T><A><F><V><H><I><L><P><V><S><F><D><K><L><G><S><P><C... | Zinc transporter that may be involved in zinc uptake from the rhizosphere.<BOP> | Q0DHE3 |
B7LUN8 | ARGE_ESCF3 | N-acetylornithinase | Escherichia | <M><K><N><K><L><P><P><F><I><E><I><Y><R><A><L><I><A><T><P><S><I><S><A><T><E><E><A><L><D><Q><S><N><A><G><L><I><T><L><L><A><D><W><F><K><D><L><G><F><N><V><E><V><Q><P><V><P><G><T><R><N><K><F><N><M><L><A><S><T><G><Q><G><A><G><G><L><L><L><A><G><H><T><D><T><V><P><F><D><D><G><R><W><T><R><D><P><F><T><L><T><E><H><D><G><K><L><Y><G... | Catalyzes the hydrolysis of the amide bond of N(2)-acetylated L-amino acids. Cleaves the acetyl group from N-acetyl-L-ornithine to form L-ornithine, an intermediate in L-arginine biosynthesis pathway, and a branchpoint in the synthesis of polyamines.<BOP> | B7LUN8 |
B2ZBA0 | DSK_DROTE | Drosulfakinin II | Sophophora | <M><G><L><R><S><C><T><H><F><A><T><L><V><M><P><L><W><A><L><A><F><C><F><L><V><L><V><P><V><P><A><Q><T><T><S><L><Q><I><S><K><G><D><R><R><L><Q><D><L><E><S><N><M><G><A><E><S><D><Q><P><N><A><N><L><V><G><T><S><L><S><R><F><G><D><K><R><N><Q><K><I><I><T><F><G><R><R><V><P><R><P><I><I><P><I><E><L><D><L><L><M><D><N><D><D><E><N><T><K... | Drosulfakinin-0 (DSK 0) plays diverse biological roles including regulating gut muscle contraction in adults but not in larvae.<BOP> | B2ZBA0 |
Q1IHH2 | RL10_KORVE | 50S ribosomal protein L10 | Candidatus Koribacter | <M><A><V><T><K><A><K><K><I><E><V><T><E><K><L><T><E><D><F><K><K><A><N><H><A><I><V><G><T><F><N><K><L><T><V><S><K><D><Y><E><L><R><K><A><V><R><S><V><G><G><K><Y><S><V><V><K><N><T><L><A><E><R><A><A><K><G><T><K><I><E><D><A><V><K><G><L><A><G><V><T><S><V><A><F><T><D><G><D><P><V><Q><L><A><K><V><L><S><K><Y><A><K><D><N><P><E><Y><E... | Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.<BOP> | Q1IHH2 |
Q326G3 | LEUC_SHIBS | Isopropylmalate isomerase | Shigella | <M><A><K><T><L><Y><E><K><L><F><D><A><H><V><V><Y><E><A><E><N><E><T><P><L><L><Y><I><D><R><H><L><V><H><E><V><T><S><P><Q><A><F><D><G><L><R><A><H><G><R><P><V><R><Q><P><G><K><T><F><A><T><M><D><H><N><V><S><T><Q><T><K><D><I><N><A><C><G><E><M><A><R><I><Q><M><Q><E><L><I><K><N><C><K><E><F><G><V><E><L><Y><D><L><N><H><P><Y><Q><G><I... | Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.<BOP> | Q326G3 |
Q0HT42 | QUEF_SHESR | PreQ(0) reductase | Shewanella | <M><T><H><N><H><D><P><Y><S><D><A><K><E><L><A><G><L><T><L><G><K><A><T><D><Y><Q><A><E><Y><D><A><S><L><L><Q><G><V><P><R><S><L><N><R><N><A><I><N><L><T><A><E><S><L><P><F><H><G><A><D><I><W><T><A><Y><E><L><S><W><L><N><A><K><G><K><P><M><V><A><I><A><D><I><Q><L><S><H><E><S><Q><N><L><I><E><S><K><S><F><K><L><Y><L><N><S><F><N><Q><T... | Catalyzes the NADPH-dependent reduction of 7-cyano-7-deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1).<BOP> | Q0HT42 |
B2INX0 | PLSY_STRPS | Lysophosphatidic acid synthase | Streptococcus | <M><I><T><I><V><L><L><I><L><A><Y><L><L><G><S><I><P><S><G><L><W><I><G><Q><V><F><F><Q><I><N><L><R><E><H><G><S><G><N><T><G><T><T><N><T><F><R><I><L><G><K><K><A><G><M><A><T><F><V><I><D><F><F><K><G><T><L><A><T><L><L><P><I><I><F><H><L><Q><G><V><S><P><L><I><F><G><L><L><A><V><I><G><H><T><F><P><I><F><A><G><F><K><G><G><K><A><V><A... | Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP.<BOP> | B2INX0 |
P06615 | REDF_ECOLI | Protein D | Escherichia | <M><S><G><S><V><I><H><S><Q><S><A><V><M><V><P><A><V><Y><S><A><G><Q><P><A><S><L><P><V><A><I><D><Y><P><A><A><L><A><L><R><Q><M><S><M><V><H><D><E><L><P><K><Y><L><L><A><P><E><V><S><A><L><L><H><Y><V><P><D><L><H><R><K><M><L><L><A><T><L><W><N><T><G><A><R><I><N><E><A><L><A><L><T><R><G><D><F><S><L><A><P><P><Y><P><F><V><Q><L><A><T... | Acts as a repressor of transcription and as a site-specific resolvase that cleaves at the RfsF site.<BOP> | P06615 |
B2UC26 | YCIB_RALPJ | Inner membrane-spanning protein YciB | Ralstonia | <M><K><F><L><F><D><L><F><P><V><I><L><F><F><A><A><F><K><V><A><G><I><Y><V><A><T><T><V><A><M><V><A><T><V><L><Q><I><A><W><V><W><F><K><H><R><K><V><D><A><M><Q><W><L><S><L><L><I><I><G><V><F><G><G><A><T><L><I><F><H><N><E><T><F><I><K><W><K><P><T><V><L><Y><W><L><F><G><V><V><L><L><G><S><V><V><V><V><R><K><N><L><I><R><A><M><M><E><Q... | Plays a role in cell envelope biogenesis, maintenance of cell envelope integrity and membrane homeostasis.<BOP> | B2UC26 |
Q5E5B6 | PYRD_ALIF1 | Dihydroorotate oxidase | Aliivibrio | <M><L><Y><R><I><A><R><A><G><I><F><K><L><D><A><E><K><A><H><D><L><A><I><Q><N><F><K><R><F><N><G><T><P><L><D><I><F><Y><R><Q><N><L><A><S><K><P><V><E><V><M><G><I><K><F><K><N><P><V><G><L><A><A><G><L><D><K><N><G><E><C><I><E><A><F><G><A><M><G><F><G><F><V><E><V><G><T><V><T><P><R><P><Q><S><G><N><D><K><P><R><L><F><R><L><I><E><A><E... | Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor.<BOP> | Q5E5B6 |
C3PFX1 | ILVC_CORA7 | Ketol-acid reductoisomerase type I | Corynebacterium | <M><A><I><E><T><L><Y><D><S><D><A><D><L><T><I><I><Q><G><R><K><V><A><I><I><G><Y><G><S><Q><G><H><A><H><A><M><N><L><R><D><S><G><V><E><V><A><I><G><L><R><E><G><S><K><S><R><E><K><A><E><E><A><G><F><K><V><L><T><N><A><E><A><A><K><W><A><D><V><I><M><L><L><A><P><D><T><S><Q><A><A><I><F><T><E><D><I><E><P><N><L><E><D><G><N><A><L><F><F... | Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobu... | C3PFX1 |
A5G9J8 | GATB_GEOUR | Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit B | Geotalea | <M><K><Y><Q><V><V><I><G><L><E><V><H><V><Q><L><L><T><N><S><K><I><F><C><G><C><S><T><R><F><G><A><E><P><N><S><Q><T><C><P><V><C><L><G><M><P><G><A><L><P><V><L><N><K><K><V><V><E><Y><A><I><R><A><G><L><A><T><N><C><R><I><A><P><R><S><V><F><A><R><K><N><Y><F><Y><P><D><L><P><K><G><Y><Q><I><S><Q><F><E><L><P><I><C><I><D><G><H><L><D><I... | Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated ... | A5G9J8 |
C3PLI9 | LPXK_RICAE | Lipid A 4'-kinase | spotted fever group | <M><I><K><L><L><Y><P><E><F><W><Q><K><R><N><I><I><A><Y><L><L><L><P><I><S><V><I><Y><Q><F><L><G><Y><L><R><A><S><L><A><R><P><I><M><L><P><A><K><V><I><C><V><G><N><C><S><V><G><G><T><G><K><T><Q><I><V><M><Y><L><A><K><L><L><K><A><R><N><V><S><F><V><I><V><T><K><A><Y><G><S><N><L><T><S><A><T><T><I><H><Q><G><H><T><A><L><E><V><G><D><E... | Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA).<BOP> | C3PLI9 |
Q6DE15 | B3G5B_XENLA | UDP-GlcNAc:beta-Gal beta-1,3-N-acetylglucosaminyltransferase 5B | Xenopus | <M><L><I><S><A><R><R><L><R><R><C><Q><S><L><Q><L><L><A><S><C><F><V><L><S><L><M><A><L><L><V><Q><E><D><N><S><L><V><N><H><V><K><S><Y><S><Y><R><Y><L><I><N><S><Y><N><F><V><N><D><S><L><S><V><P><R><D><R><S><D><G><A><A><G><Y><R><Y><L><I><N><N><R><H><K><C><L><N><E><D><V><L><L><L><L><F><V><K><T><A><P><E><N><R><R><R><R><N><A><I><R... | Beta-1,3-N-acetylglucosaminyltransferase that plays a key role in the synthesis of lacto- or neolacto-series carbohydrate chains on glycolipids.<BOP> | Q6DE15 |
C0Q067 | ARNT_SALPC | Undecaprenyl phosphate-alpha-L-Ara4N transferase | Salmonella | <M><M><K><S><I><R><Y><Y><L><A><F><A><A><F><I><A><L><Y><Y><V><I><P><V><N><S><R><L><L><W><Q><P><D><E><T><R><Y><A><E><I><S><R><E><M><L><A><S><G><D><W><I><V><P><H><F><L><G><L><R><Y><F><E><K><P><I><A><G><Y><W><I><N><S><L><G><Q><W><L><F><G><A><T><N><F><G><V><R><A><G><A><I><L><T><T><L><L><A><A><A><L><V><A><W><L><T><F><R><L><W... | Catalyzes the transfer of the L-Ara4N moiety of the glycolipid undecaprenyl phosphate-alpha-L-Ara4N to lipid A. The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides.<BOP> | C0Q067 |
B5Z950 | RSMA_HELPG | S-adenosylmethionine-6-N', N'-adenosyl(rRNA) dimethyltransferase | Helicobacter | <M><V><V><A><K><K><S><L><G><Q><H><F><L><T><D><E><S><F><L><D><R><I><V><N><A><L><P><P><L><N><P><L><K><L><I><E><I><G><V><G><L><G><D><L><T><L><K><L><L><D><R><Y><P><L><K><T><Y><E><I><D><S><N><L><C><E><K><M><R><A><R><L><K><A><Q><K><K><P><F><Q><L><E><L><V><E><K><D><A><L><F><L><K><E><E><E><P><Y><F><L><I><S><N><L><P><Y><Y><I><A... | Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits.<BOP> | B5Z950 |
Q7NPZ4 | MURE_CHRVO | UDP-N-acetylmuramyl-tripeptide synthetase | Chromobacterium | <M><K><S><R><L><T><A><L><P><D><W><D><P><A><L><L><Q><Q><L><G><L><P><I><K><R><V><E><A><D><S><R><R><V><L><P><G><D><V><F><L><A><C><R><G><E><Y><A><D><G><R><D><F><I><P><A><A><L><E><K><G><A><A><A><V><L><W><D><E><A><D><G><F><A><W><K><A><E><W><Q><A><P><N><L><A><V><P><N><L><R><E><R><A><G><I><V><A><A><H><V><L><G><L><P><S><R><D><L... | Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan.<BOP> | Q7NPZ4 |
F4HUC4 | ATCA5_ARATH | Alpha carbonate dehydratase 5 | Arabidopsis | <M><K><I><P><S><I><G><Y><V><F><F><L><I><F><I><S><I><T><I><V><S><S><S><P><D><H><G><E><V><E><D><E><T><Q><F><N><Y><E><K><K><G><E><K><G><P><E><N><W><G><R><L><K><P><E><W><A><M><C><G><K><G><N><M><Q><S><P><I><D><L><T><D><K><R><V><L><I><D><H><N><L><G><Y><L><R><S><Q><Y><L><P><S><N><A><T><I><K><N><R><G><H><D><I><M><M><K><F><E><G... | Reversible hydration of carbon dioxide.<BOP> | F4HUC4 |
Q824Y6 | NQRA_CHLCV | NQR-1 subunit A | Chlamydia | <M><K><I><A><I><T><R><G><L><D><L><S><L><Q><G><S><P><K><E><S><G><F><L><K><R><I><D><P><A><L><V><S><V><D><L><R><P><Y><S><A><L><A><L><K><L><K><V><E><Q><D><D><V><I><S><S><G><S><P><I><A><E><Y><K><N><F><P><G><V><F><I><T><S><P><V><S><G><I><V><K><E><I><R><R><G><E><K><R><S><L><L><D><V><V><I><K><K><T><P><G><Q><N><L><T><E><Y><S><Y... | NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol.<BOP> | Q824Y6 |
B9DI94 | RNPA_STACT | Protein C5 | Staphylococcus | <M><E><K><A><Y><R><I><K><K><N><S><D><F><Q><A><I><Y><R><R><G><K><S><V><A><N><R><Q><F><V><I><Y><M><M><P><D><K><G><L><T><H><F><K><L><G><I><S><V><S><K><K><L><G><N><A><V><T><R><N><R><I><K><R><A><I><R><E><N><F><K><V><H><K><D><D><M><L><P><R><N><I><I><V><I><A><R><H><P><A><K><D><M><T><V><L><E><I><Q><K><S><L><E><H><V><L><K><V><A... | RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the riboz... | B9DI94 |
Q2YTP0 | MENE_STAAB | o-succinylbenzoyl-CoA synthetase | Staphylococcus | <M><D><F><W><L><Y><K><Q><A><Q><Q><N><G><H><H><I><A><I><T><D><G><Q><E><S><Y><T><Y><Q><N><L><Y><C><E><A><S><L><L><A><K><R><L><K><A><Y><Q><Q><S><R><V><G><L><Y><I><D><N><S><I><Q><S><I><I><L><I><H><A><C><W><L><A><N><I><E><I><A><M><I><N><T><R><L><T><P><N><E><M><K><N><Q><M><R><S><I><D><V><Q><L><I><F><C><T><L><P><L><E><L><R><G... | Converts 2-succinylbenzoate (OSB) to 2-succinylbenzoyl-CoA (OSB-CoA).<BOP> | Q2YTP0 |
Q0HH38 | PSTB_SHESM | Phosphate-transporting ATPase | Shewanella | <M><I><S><I><D><S><T><A><M><K><T><N><N><F><D><L><A><N><L><S><Q><N><D><T><A><L><E><I><R><N><L><D><L><R><Y><G><D><K><Q><A><L><F><N><V><S><M><K><I><P><K><K><Q><V><T><A><F><I><G><P><S><G><C><G><K><S><T><L><L><R><C><I><N><R><M><N><D><L><V><D><N><C><H><I><D><G><E><I><L><L><H><G><Q><N><I><Y><D><K><K><I><D><V><A><A><L><R><R><N... | Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system.<BOP> | Q0HH38 |
Q9SHC8 | VAP12_ARATH | Vesicle-associated protein 1-2, N-terminally processed | Arabidopsis | <M><S><N><E><L><L><T><I><D><P><V><D><L><Q><F><P><F><E><L><K><K><Q><I><S><C><S><L><Y><L><G><N><K><T><D><N><Y><V><A><F><K><V><K><T><T><N><P><K><K><Y><C><V><R><P><N><T><G><V><V><H><P><R><S><S><S><E><V><L><V><T><M><Q><A><Q><K><E><A><P><A><D><L><Q><C><K><D><K><F><L><L><Q><C><V><V><A><S><P><G><A><T><P><K><D><V><T><H><E><M><F... | Vesicle-associated protein that binds the oxysterol-binding protein ORP3A and allows its targeting to the ER.<BOP> | Q9SHC8 |
Q68VY3 | KGUA_RICTY | GMP kinase | typhus group | <M><Q><F><K><H><K><G><L><I><I><I><L><S><S><P><S><G><T><G><K><S><S><L><A><K><E><L><L><K><I><D><N><N><L><R><L><S><I><S><V><T><T><R><K><P><R><L><G><E><V><D><G><I><N><Y><Y><F><K><T><D><L><E><F><K><T><L><V><K><Q><N><K><F><L><E><Y><A><K><I><Y><N><D><Y><Y><G><T><P><K><E><Y><V><K><M><L><L><K><Q><G><L><D><V><L><F><D><I><D><W><Q... | Essential for recycling GMP and indirectly, cGMP.<BOP> | Q68VY3 |
O84172 | TRPB_CHLTR | Tryptophan synthase beta chain | Chlamydia | <M><F><K><H><K><H><P><F><G><G><A><F><L><P><E><E><L><L><A><P><I><Q><N><L><K><A><E><W><E><I><L><K><T><Q><Q><S><F><L><S><E><L><D><C><I><L><K><N><Y><A><G><R><Q><T><P><L><T><E><V><K><N><F><A><R><A><I><D><G><P><R><V><F><L><K><R><E><D><L><L><H><T><G><A><H><K><L><N><N><A><L><G><Q><C><L><L><A><K><Y><L><G><K><T><R><V><V><A><E><T... | The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.<BOP> | O84172 |
O34691 | NAIP_BACSU | Putative niacin/nicotinamide transporter NaiP | Bacillus | <M><G><K><Q><Q><P><I><S><Q><R><K><L><L><G><V><A><G><L><G><W><L><F><D><A><M><D><V><G><I><L><S><F><I><I><A><A><L><H><V><E><W><N><L><S><P><E><E><M><K><W><I><G><S><V><N><S><I><G><M><A><A><G><A><F><L><F><G><L><L><A><D><R><I><G><R><K><K><V><F><I><I><T><L><L><C><F><S><I><G><S><G><I><S><A><F><V><T><S><L><S><A><F><L><I><L><R><F... | Probably involved in the uptake of amidated and deamidated forms of niacin. Increases the growth rate of E.coli that is unable to make niacin de novo; confers increased sensitivity to the toxic niacin analog 6-amino-nicotinamide to wild-type E.coli. There is probably another mechanism for niacin uptake.<BOP> | O34691 |
A8A7B3 | ACEK_ECOHS | Isocitrate dehydrogenase kinase/phosphatase | Escherichia | <M><P><R><G><L><E><L><L><I><A><Q><T><I><L><Q><G><F><D><A><Q><Y><G><R><F><L><E><V><T><S><G><A><Q><Q><R><F><E><Q><A><D><W><H><A><V><Q><Q><A><M><K><N><R><I><H><L><Y><D><H><H><V><G><L><V><V><E><Q><L><R><C><I><T><N><G><Q><S><T><D><A><A><F><L><L><R><V><K><E><H><Y><T><R><L><L><P><D><Y><P><R><F><E><I><A><E><S><F><F><N><S><V><Y... | Bifunctional enzyme which can phosphorylate or dephosphorylate isocitrate dehydrogenase (IDH) on a specific serine residue. This is a regulatory mechanism which enables bacteria to bypass the Krebs cycle via the glyoxylate shunt in response to the source of carbon. When bacteria are grown on glucose, IDH is fully activ... | A8A7B3 |
Q8R092 | CA043_MOUSE | Protein C1orf43 homolog | Mus | <M><A><S><S><S><N><W><L><S><G><V><N><V><V><L><V><M><A><Y><G><S><L><V><F><V><L><L><F><I><F><V><K><R><Q><I><M><R><F><A><M><K><S><R><R><G><P><H><V><P><V><G><H><N><A><P><K><D><L><K><E><E><I><D><I><R><L><S><R><V><Q><D><I><K><Y><E><P><Q><L><L><A><D><D><D><T><R><L><L><Q><L><E><T><Q><G><N><Q><S><C><Y><N><Y><L><Y><R><M><K><A><L... | General regulator of phagocytosis. Required to uptake Gram negative bacterium by macrophages.<BOP> | Q8R092 |
B8EE63 | CYSC_SHEB2 | Adenosine-5'-phosphosulfate kinase | Shewanella | <M><T><N><I><V><W><H><Q><H><P><V><D><Q><A><A><R><A><E><Q><K><G><Q><N><P><V><L><L><W><F><T><G><L><S><G><A><G><K><S><T><L><A><G><A><L><E><R><A><L><F><E><A><G><F><H><T><Y><L><L><D><G><D><N><V><R><H><G><L><C><K><D><L><G><F><T><V><E><D><R><D><E><N><L><R><R><V><G><E><V><A><K><L><M><V><D><A><G><L><V><V><L><S><A><F><I><S><P><T... | Catalyzes the synthesis of activated sulfate.<BOP> | B8EE63 |
Q0G9V9 | NDHJ_DAUCA | NADH-plastoquinone oxidoreductase subunit J | Daucus sect. Daucus | <M><Q><G><R><L><S><A><W><L><V><K><H><G><L><I><H><R><S><L><G><F><D><Y><Q><G><I><E><T><L><Q><I><K><P><E><D><W><H><S><I><A><V><I><L><Y><I><Y><G><Y><N><Y><L><R><S><Q><C><A><Y><D><V><A><P><G><G><L><L><A><S><V><Y><H><L><T><R><I><E><Y><G><V><D><Q><P><E><E><V><C><I><K><V><F><S><P><R><K><N><P><R><I><P><S><V><F><W><V><W><K><G><V... | NDH shuttles electrons from NAD(P)H:plastoquinone, via FMN and iron-sulfur (Fe-S) centers, to quinones in the photosynthetic chain and possibly in a chloroplast respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translo... | Q0G9V9 |
Q3BNL9 | DTD_XANC5 | Gly-tRNA(Ala) deacylase | Xanthomonas | <M><L><A><L><I><Q><R><V><T><R><A><A><V><T><V><D><D><Q><I><V><G><Q><I><G><P><G><L><L><A><L><I><G><V><E><P><G><D><S><D><A><Q><I><R><R><L><A><E><R><L><L><S><Y><R><V><F><G><D><D><A><G><K><M><N><R><S><L><T><D><T><G><G><G><L><L><L><V><S><Q><F><T><L><A><A><D><T><S><S><G><N><R><P><G><F><S><T><A><A><P><P><L><E><A><E><P><A><F><N... | An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA-based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site. By rec... | Q3BNL9 |
Q0UWF6 | PXR1_PHANO | PinX1-related protein 1 | Parastagonospora | <M><G><L><A><A><P><K><N><R><S><K><I><S><N><D><P><Q><N><T><T><W><A><N><N><T><S><R><F><G><H><R><I><L><T><S><Q><G><W><Q><P><G><D><S><L><G><A><S><D><A><A><H><A><A><H><Y><T><V><A><S><Q><S><H><I><R><V><L><L><K><D><D><N><L><G><L><G><A><K><R><G><S><E><R><A><E><N><F><G><L><A><G><L><E><S><I><L><G><R><L><N><G><K><E><A><E><V><K><K... | Involved in rRNA-processing at A0, A1 and A2 sites and regulates negatively telomerase.<BOP> | Q0UWF6 |
Q0HJT7 | MNMA_SHESM | tRNA-specific 2-thiouridylase MnmA | Shewanella | <M><T><S><I><E><P><T><H><T><G><K><K><V><I><V><G><M><S><G><G><V><D><S><S><V><S><A><Y><L><L><M><Q><Q><G><Y><Q><V><E><G><L><F><M><K><N><W><E><E><D><D><N><D><E><Y><C><A><A><A><E><D><L><K><D><A><Q><A><V><C><D><K><L><G><I><K><L><H><T><V><N><F><A><A><E><Y><W><D><N><V><F><E><Y><F><L><A><E><Y><K><A><G><R><T><P><N><P><D><I><M><C... | Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.<BOP> | Q0HJT7 |
B1P1G5 | JZT40_CHIGU | Jingzhaotoxin-40 | Chilobrachys | <M><K><V><S><V><L><I><T><L><A><V><L><G><V><M><F><L><L><T><S><A><E><E><R><G><S><D><Q><M><D><S><P><A><W><L><K><S><M><E><R><I><F><Q><S><E><E><R><E><C><R><W><L><F><G><G><C><E><K><D><S><D><C><C><E><H><L><G><C><R><R><T><K><P><S><W><C><G><W><D><F><T><F><G><K> | Probable ion channel inhibitor.<BOP> | B1P1G5 |
C3MAY2 | RL23_SINFN | 50S ribosomal protein L23 | Sinorhizobium | <M><T><D><L><R><H><Y><D><V><I><V><S><P><S><I><T><E><K><S><T><L><V><S><E><Q><N><Q><V><V><F><N><V><A><K><G><A><S><K><P><E><I><K><A><A><V><E><A><L><F><G><V><K><V><T><A><V><N><T><L><V><R><K><G><K><L><K><R><F><R><G><F><A><G><K><Q><K><D><V><K><K><A><I><I><T><L><A><E><G><Q><S><I><D><V><S><T><G><L> | One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome.<BOP> | C3MAY2 |
Q58597 | SYT_METJA | Threonyl-tRNA synthetase | Methanocaldococcus | <M><K><M><L><L><I><H><S><D><Y><L><E><F><E><A><K><E><K><T><K><I><A><E><E><T><E><N><L><K><G><K><L><D><E><C><L><A><C><F><I><A><V><E><R><E><D><E><N><N><P><E><G><T><A><I><G><A><V><E><E><I><E><K><V><A><N><Q><L><K><V><N><N><I><V><V><Y><P><Y><A><H><L><S><S><D><L><S><S><P><E><T><A><V><K><V><L><K><D><I><E><S><I><L><K><E><R><G><Y... | Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction: L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr) . Also activates L-serine, but does not detectably transfer it to tRNA(Thr) . Edits incorrectly charged L-seryl-tRNA(Thr) via its editing... | Q58597 |
A1TQ97 | KDSB_ACIAC | CMP-2-keto-3-deoxyoctulosonic acid synthase | Acidovorax | <M><S><G><G><A><A><S><A><G><F><T><V><L><I><P><A><R><L><A><S><T><R><L><P><D><K><P><L><A><D><I><G><G><I><P><M><V><V><R><V><A><Q><Q><A><A><R><S><R><A><A><R><V><V><V><A><A><D><H><P><R><I><L><E><A><C><A><A><H><G><V><Q><A><V><A><T><R><A><D><H><P><S><G><S><D><R><L><A><E><A><C><V><Q><L><G><L><A><D><D><D><V><V><V><N><V><Q><G><D... | Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria.<BOP> | A1TQ97 |
A1A900 | GAL1_ECOK1 | Galactose kinase | Escherichia | <M><S><L><K><E><K><T><Q><S><L><F><A><N><A><F><G><Y><P><A><T><H><T><I><Q><A><P><G><R><V><N><L><I><G><E><H><T><D><Y><N><D><G><F><V><L><P><C><A><I><D><Y><Q><T><V><I><S><C><A><P><R><D><D><R><K><V><R><V><M><A><A><D><Y><E><N><Q><L><D><E><F><S><L><D><A><P><I><V><A><H><E><N><Y><Q><W><A><N><Y><V><R><G><V><V><K><H><L><Q><L><R><N... | Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P).<BOP> | A1A900 |
Q730U2 | TCYP_BACC1 | Transporter of cystine TcyP | Bacillus cereus group | <M><N><T><L><L><V><G><I><N><V><A><V><M><L><I><L><V><G><V><L><Y><Y><M><Q><R><K><H><V><S><F><N><K><R><V><F><T><A><L><G><V><G><I><I><F><G><L><I><L><Q><F><I><Y><E><P><T><S><K><V><I><I><E><S><N><T><W><F><G><L><I><G><N><G><Y><V><K><L><L><Q><M><I><V><M><P><L><I><L><V><S><I><I><S><A><F><T><K><L><Q><L><T><K><N><L><G><K><I><S><G... | Mediates uptake of L-cystine, the oxidized form of L-cysteine.<BOP> | Q730U2 |
Q9SXW9 | PLAS_PHYPA | Plastocyanin, chloroplastic | Physcomitrium | <M><A><S><V><A><A><A><A><V><S><V><P><S><F><S><G><L><K><A><E><T><K><A><A><P><A><R><L><S><S><T><S><V><V><R><M><A><P><V><V><R><A><S><A><S><S><D><A><L><K><T><V><G><K><A><L><L><A><A><S><S><S><L><L><L><V><A><S><A><N><A><A><T><V><K><M><G><G><D><D><G><A><L><G><F><Y><P><K><D><I><S><V><A><A><G><E><S><V><T><F><V><N><N><K><G><F><P... | Participates in electron transfer between P700 and the cytochrome b6-f complex in photosystem I.<BOP> | Q9SXW9 |
O75601 | CASPD_BOVIN | Caspase-13 subunit 2 | Bos | <M><A><E><D><K><H><N><K><N><P><L><K><M><L><E><S><L><G><K><E><L><I><S><G><L><L><D><D><F><V><E><K><N><V><L><K><L><E><E><E><E><K><K><K><I><Y><D><A><K><L><Q><D><K><A><R><V><L><V><D><S><I><R><Q><K><N><Q><E><A><G><Q><V><F><V><Q><T><F><L><N><I><D><K><N><S><T><S><I><K><A><P><E><E><T><V><A><G><P><D><E><S><V><G><S><A><A><T><L><K... | Involved in the activation cascade of caspases responsible for apoptosis execution. Might function by either activating some proteins required for cell death or inactivating proteins necessary for cell survival.<BOP> | O75601 |
Q97GF7 | RECX_CLOAB | Regulatory protein RecX | Clostridium | <M><E><E><N><T><I><T><K><I><E><A><Q><K><K><K><K><D><R><V><N><V><Y><I><D><N><E><Y><S><F><S><C><N><T><E><L><I><Y><I><H><G><L><K><K><G><K><V><V><D><L><D><Y><L><Q><D><I><I><E><E><D><N><Y><L><Y><A><K><S><R><A><L><S><F><I><E><K><T><F><K><T><E><K><E><I><R><V><K><L><R><E><K><E><F><N><E><K><I><I><E><R><V><I><E><F><L><R><K><Y><D... | Modulates RecA activity.<BOP> | Q97GF7 |
Q5FQB9 | TOLB_GLUOX | Tol-Pal system protein TolB | Gluconobacter | <M><S><F><I><P><N><T><E><A><E><A><L><S><A><L><F><S><R><R><S><V><L><G><A><T><A><A><G><G><L><L><A><T><P><L><A><A><F><A><Q><S><G><A><A><S><G><P><G><E><A><E><I><T><V><D><Q><A><R><Q><E><P><I><P><I><V><V><P><N><F><G><A><G><L><G><E><Q><I><S><G><V><I><T><S><D><L><N><G><T><G><L><F><K><V><M><S><G><S><V><P><P><G><S><T><P><D><F><S... | Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.<BOP> | Q5FQB9 |
B1ZKE5 | NDK_METPB | Nucleoside-2-P kinase | Methylorubrum | <M><A><N><E><R><T><F><S><I><L><K><P><D><A><T><R><R><N><I><T><G><A><V><N><A><V><I><E><A><A><G><L><R><I><V><G><Q><R><R><I><R><M><T><R><A><Q><A><E><K><F><Y><E><V><H><K><E><R><P><F><F><G><E><L><V><E><F><M><T><S><G><P><V><V><V><Q><V><L><E><G><E><N><A><V><A><K><Y><R><E><V><M><G><A><T><N><P><A><Q><A><A><D><G><T><I><R><K><Q><F... | Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.<BOP> | B1ZKE5 |
A4XBL2 | THIE_SALTO | Thiamine-phosphate pyrophosphorylase | Salinispora | <M><S><S><L><G><R><L><H><L><I><T><D><A><R><A><G><R><N><P><L><T><V><V><Q><A><A><L><S><V><A><R><T><E><L><V><V><Q><V><R><V><A><D><D><A><T><D><R><Q><A><Y><D><L><A><R><R><V><I><A><L><C><A><R><Y><D><A><T><C><L><V><N><D><R><L><H><V><A><L><A><V><G><A><A><G><G><H><V><G><A><D><D><L><P><V><G><A><A><R><A><V><L><G><S><A><A><V><L><G... | Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP).<BOP> | A4XBL2 |
P10322 | NO25_MEDSA | Nodulin-25 | Medicago | <M><V><Y><S><N><T><Y><M><L><L><G><L><G><V><F><V><L><L><S><S><H><V><L><A><Y><N><M><R><A><D><P><S><I><H><D><S><T><L><D><D><Q><K><S><N><D><F><V><K><T><A><S><I><A><E><C><P><P><G><P><D><T><Y><L><E><L><S><D><S><T><L><D><D><Q><K><S><M><D><Y><V><K><D><A><S><T><V><D><H><N><C><P><P><G><P><H><T><Y><L><E><L><S><A><W><L><Q><E><E><Q... | Involved in the development and function of nodules. It might participate in the biological process of symbiotic nitrogen fixation.<BOP> | P10322 |
O94339 | MUG96_SCHPO | Meiotically up-regulated gene 96 protein | Schizosaccharomyces | <M><V><I><F><S><S><Y><F><S><K><Q><M><N><R><F><S><T><P><F><V><F><F><F><K><K><L><N><N><T><L><K><K><S><L><Q><F><I><M><R><F><H><S><Y><H><P><M><F><I><C><L><L><R><D><S><S><R><N><E><N><R><K><K><K><V><S><I><G><L><R><T><I><M><R><A><F><S><F><L><M><Q><V><A><T><C><L><I><R><Y><S><L><I><L><T><C><L><V><A><I><L><L><S><V><L><W><R><I><Q... | Has a role in meiosis.<BOP> | O94339 |
B8DHE9 | THII_LISMH | tRNA 4-thiouridine synthase | Listeria | <M><E><F><D><R><M><L><I><R><Y><G><E><L><S><T><K><G><K><N><R><K><Q><F><V><T><K><L><A><Q><N><V><K><R><A><M><T><D><L><P><E><V><R><I><H><G><E><R><D><R><M><Y><I><I><L><N><G><A><D><Y><Q><L><A><E><E><R><L><K><P><I><F><G><I><Q><S><F><S><P><A><V><R><V><N><L><D><L><E><E><V><K><A><A><A><L><A><L><V><Q><D><A><H><E><E><N><G><T><F><K... | Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynt... | B8DHE9 |
Q3ZXL7 | HISX_DEHMC | Histidinol dehydrogenase | Dehalococcoides | <M><K><I><I><R><G><F><A><Q><A><E><K><R><L><S><R><R><D><K><A><G><F><F><L><D><E><T><E><R><T><E><L><A><R><R><L><G><V><D><P><E><K><A><V><N><G><I><I><A><D><V><R><K><Q><G><D><E><A><V><L><G><Y><T><L><K><F><D><R><A><N><L><S><K><L><E><V><G><Q><P><E><I><Q><Q><A><A><S><E><I><P><A><E><L><F><E><A><L><Q><L><A><A><S><Q><I><R><A><Y><H... | Catalyzes the sequential NAD-dependent oxidations of L-histidinol to L-histidinaldehyde and then to L-histidine.<BOP> | Q3ZXL7 |
B3GZE5 | RL21_ACTP7 | 50S ribosomal protein L21 | Actinobacillus | <M><Y><A><V><F><Q><S><G><G><K><Q><H><R><V><S><E><G><Q><V><V><R><L><E><K><L><E><I><A><T><G><E><K><F><E><F><D><S><V><L><M><V><V><N><G><E><D><V><K><I><G><A><P><V><V><A><G><A><K><V><V><A><E><V><V><A><Q><G><R><G><D><K><V><K><I><V><K><F><R><R><R><K><H><S><R><K><Q><Q><G><H><R><Q><W><F><T><E><V><K><I><T><G><I><Q><A> | This protein binds to 23S rRNA in the presence of protein L20.<BOP> | B3GZE5 |
Q5R5Y3 | B3GT2_PONAB | UDP-galactose:2-acetamido-2-deoxy-D-glucose 3beta-galactosyltransferase 2 | Pongo | <M><L><Q><W><R><R><R><H><C><C><F><A><K><M><T><W><N><A><K><R><S><L><F><R><T><H><L><I><G><V><L><S><L><V><F><L><F><A><M><F><L><F><F><N><H><H><D><W><L><P><G><R><A><G><F><K><E><N><P><V><T><Y><T><F><R><G><F><R><S><T><K><S><E><T><N><H><S><S><L><R><N><I><W><K><E><T><V><P><Q><T><L><R><P><Q><T><A><T><N><S><N><N><T><D><L><S><P><Q... | Beta-1,3-galactosyltransferase that transfers galactose from UDP-galactose to substrates with a terminal beta-N-acetylglucosamine (beta-GlcNAc) residue. Can also utilize substrates with a terminal galactose residue, albeit with lower efficiency. Involved in the biosynthesis of the carbohydrate moieties of glycolipids a... | Q5R5Y3 |
Q7TS73 | RFLA_MOUSE | Regulator of filamin protein A | Mus | <M><V><G><H><L><H><L><Q><A><M><G><D><T><R><E><Q><S><R><D><G><L><L><D><S><P><D><S><G><L><P><P><S><P><S><P><S><P><P><F><Y><A><L><S><P><G><T><L><D><T><R><T><T><T><E><A><P><A><A><P><S><L><F><Q><T><P><P><A><L><E><M><R><S><R><L><L><P><V><F><F><G><E><S><I><E><V><D><P><E><P><A><H><E><I><R><C><N><S><E><I><T><Y><A><S><E><R><Y><F... | Involved in the regulation of the perinuclear actin network and nuclear shape through interaction with filamins. Plays an essential role in the formation of cartilaginous skeletal elements.<BOP> | Q7TS73 |
C4L2E7 | OAT_EXISA | Ornithine--oxo-acid aminotransferase | unclassified Exiguobacterium | <M><S><K><T><H><D><V><I><E><L><T><E><K><F><G><A><H><N><Y><H><P><L><P><I><V><I><S><E><A><K><G><I><W><V><T><D><P><E><G><N><R><Y><M><D><M><L><S><A><Y><S><A><V><N><Q><G><H><C><H><P><K><I><I><Q><A><L><K><D><Q><A><D><K><I><T><L><T><S><R><A><F><Y><N><D><Q><L><G><R><F><Y><D><K><V><V><T><L><T><K><K><Q><M><V><L><P><M><N><T><G><A... | Catalyzes the interconversion of ornithine to glutamate semialdehyde.<BOP> | C4L2E7 |
Q6BIS2 | YPT35_DEBHA | PX domain-containing protein YPT35 | Debaryomyces | <M><T><A><S><N><R><R><G><S><T><H><R><N><S><V><T><Q><L><N><K><V><L><P><V><P><I><Q><L><E><D><E><T><S><S><G><H><F><N><S><T><S><H><I><T><D><V><L><V><G><D><Y><H><V><I><Q><G><E><G><G><S><S><Y><V><V><W><S><I><R><I><I><V><D><D><S><V><Y><S><S><M><V><I><Y><K><R><Y><S><D><I><Q><R><F><R><E><A><L><L><E><H><Y><P><N><T><E><I><P><P><L... | Recruits the lipid transfer protein VPS13 to endosomal and vacuolar membranes.<BOP> | Q6BIS2 |
Q3ZJ62 | PSBI_TUPAK | PSII 4.8 kDa protein | Tupiella | <M><L><T><L><K><I><F><V><Y><T><V><V><T><F><F><V><S><L><F><I><F><G><F><L><S><N><D><P><G><R><N><P><N><Q><R> | One of the components of the core complex of photosystem II (PSII), required for its stability and/or assembly. PSII is a light-driven water:plastoquinone oxidoreductase that uses light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation. It consists of a c... | Q3ZJ62 |
Q04837 | SSBP_HUMAN | PWP1-interacting protein 17 | Homo | <M><F><R><R><P><V><L><Q><V><L><R><Q><F><V><R><H><E><S><E><T><T><T><S><L><V><L><E><R><S><L><N><R><V><H><L><L><G><R><V><G><Q><D><P><V><L><R><Q><V><E><G><K><N><P><V><T><I><F><S><L><A><T><N><E><M><W><R><S><G><D><S><E><V><Y><Q><L><G><D><V><S><Q><K><T><T><W><H><R><I><S><V><F><R><P><G><L><R><D><V><A><Y><Q><Y><V><K><K><G><S><R... | Binds preferentially and cooperatively to pyrimidine rich single-stranded DNA (ss-DNA) . In vitro, required to maintain the copy number of mitochondrial DNA (mtDNA) and plays a crucial role during mtDNA replication by stimulating the activity of the replisome components POLG and TWNK at the replication fork . Promotes ... | Q04837 |
P56990 | GLYA_NEIMB | Serine hydroxymethyltransferase | Neisseria | <M><F><S><K><S><V><T><L><A><Q><Y><D><P><D><L><A><A><A><I><A><Q><E><D><Q><R><Q><Q><D><H><V><E><L><I><A><S><E><N><Y><V><S><C><A><V><M><D><A><Q><G><S><Q><L><T><N><K><Y><A><E><G><Y><P><G><K><R><Y><Y><G><G><C><E><Y><V><D><I><V><E><Q><L><A><I><D><R><V><K><E><L><F><G><A><A><Y><A><N><V><Q><P><H><S><G><S><Q><A><N><Q><A><V><Y><A... | Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent a... | P56990 |
Q5M1E2 | NRDR_STRT1 | Transcriptional repressor NrdR | Streptococcus | <M><R><C><P><K><C><Q><H><N><K><S><N><V><I><D><S><R><Q><A><E><D><G><N><T><I><R><R><R><R><E><C><D><A><C><H><A><R><F><T><T><F><E><R><V><E><E><V><P><L><L><V><V><K><K><D><G><T><R><E><Q><F><S><R><D><K><I><F><N><G><I><L><M><S><A><Q><K><R><P><V><S><S><E><D><I><E><N><A><I><T><R><I><E><Q><N><I><R><R><N><H><D><G><E><V><D><S><E><V... | Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes.<BOP> | Q5M1E2 |
Q92RM4 | RNH2_RHIME | Ribonuclease HII | Sinorhizobium | <M><S><R><R><K><Q><P><D><S><P><L><F><P><L><Q><A><P><V><P><D><F><T><F><E><R><A><A><H><R><D><G><F><W><P><V><A><G><A><D><E><A><G><R><G><P><L><A><G><P><V><V><A><A><A><V><I><L><D><P><D><A><I><P><A><G><L><N><D><S><K><L><L><T><A><E><Q><R><E><A><L><F><E><E><I><L><A><T><S><T><V><S><I><A><S><S><S><S><A><R><I><D><T><T><D><I><L><K... | Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.<BOP> | Q92RM4 |
Q8D252 | RPIA_WIGBR | Phosphoriboisomerase A | Wigglesworthia | <M><I><E><E><K><L><K><K><Q><A><A><W><A><A><I><K><Y><I><K><P><G><D><I><V><G><V><G><S><G><S><T><A><E><Y><F><I><D><A><L><G><S><I><K><N><L><I><K><G><T><V><S><S><S><R><I><S><S><S><K><L><K><D><L><N><I><P><L><F><D><L><N><E><V><S><L><L><N><I><Y><V><D><G><A><D><E><I><N><Q><K><K><H><M><I><K><G><K><G><A><A><L><T><R><E><K><I><I><A... | Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate.<BOP> | Q8D252 |
O95935 | TBX18_HUMAN | T-box transcription factor TBX18 | Homo | <M><A><E><K><R><R><G><S><P><C><S><M><L><S><L><K><A><H><A><F><S><V><E><A><L><I><G><A><E><K><Q><Q><Q><L><Q><K><K><R><R><K><L><G><A><E><E><A><A><G><A><V><D><D><G><G><C><S><R><G><G><G><A><G><E><K><G><S><S><E><G><D><E><G><A><A><L><P><P><P><A><G><A><T><S><G><P><A><R><S><G><A><D><L><E><R><G><A><A><G><G><C><E><D><G><F><Q><Q><G... | Acts as transcriptional repressor involved in developmental processes of a variety of tissues and organs, including the heart and coronary vessels, the ureter and the vertebral column. Required for embryonic development of the sino atrial node (SAN) head area.<BOP> | O95935 |
P46904 | NATB_BACSU | ABC-type Na(+) transporter | Bacillus | <M><L><S><H><I><Y><K><K><E><M><I><D><A><L><R><D><R><K><T><I><L><L><T><I><L><V><P><M><I><M><M><L><G><L><V><F><F><Y><E><S><M><L><S><D><K><G><E><Q><Y><T><L><A><V><G><H><S><L><P><P><A><L><E><S><K><L><N><E><I><D><E><I><S><V><K><T><F><A><K><P><E><E><A><V><D><E><G><K><A><D><A><Y><L><N><V><P><K><E><F><D><S><Y><V><N><S><M><T><P... | Part of an ABC transporter that catalyzes ATP-dependent electrogenic sodium extrusion.<BOP> | P46904 |
B0KFT9 | GMHA_PSEPG | Sedoheptulose 7-phosphate isomerase | Pseudomonas | <M><D><M><Q><S><R><I><R><R><L><F><Q><A><S><I><D><T><K><Q><Q><A><M><D><I><L><A><P><H><I><E><Q><A><S><L><V><M><V><N><A><L><L><N><E><G><K><M><L><A><C><G><N><G><G><S><A><G><D><A><Q><H><F><S><S><E><L><L><N><R><F><E><R><E><R><P><S><L><P><A><I><A><L><T><T><D><S><S><T><L><T><S><I><A><N><D><Y><S><Y><N><E><V><F><S><K><Q><I><R><A... | Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate.<BOP> | B0KFT9 |
Q5WM31 | DNAA_ALKCK | Chromosomal replication initiator protein DnaA | Alkalihalobacillus | <M><E><N><I><D><D><L><W><N><K><V><L><E><E><M><K><K><K><V><S><K><P><S><Y><E><T><W><L><R><A><T><K><A><N><A><L><Q><N><N><D><T><I><I><V><T><A><P><N><E><F><A><R><D><W><L><E><D><H><Y><S><G><L><T><S><D><I><I><E><Q><L><T><G><A><R><L><T><P><K><F><V><I><P><Q><H><N><Q><E><E><E><A><L><P><E><Q><T><P><Q><T><P><P><E><K><D><V><A><G><Q... | Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids.<BOP> | Q5WM31 |
A5DPE3 | EF1A_PICGU | Elongation factor 1-alpha | Meyerozyma | <M><G><K><E><K><T><H><V><N><V><V><V><I><G><H><V><D><S><G><K><S><T><T><T><G><H><L><I><Y><K><C><G><G><I><D><K><R><T><I><E><K><F><E><K><E><A><A><E><L><G><K><G><S><F><K><Y><A><W><V><L><D><K><L><K><A><E><R><E><R><G><I><T><I><D><I><A><L><W><K><F><E><T><P><K><Y><H><V><T><V><I><D><A><P><G><H><R><D><F><I><K><N><M><I><T><G><T><S... | This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.<BOP> | A5DPE3 |
B8NM66 | USTA_ASPFN | YAIG-XVI | Aspergillus subgen. Circumdati | <M><K><L><I><L><T><L><L><V><S><G><L><C><A><L><A><A><P><A><A><K><R><D><G><V><E><D><Y><A><I><G><I><D><K><R><N><S><V><E><D><Y><A><I><G><I><D><K><R><N><S><V><E><D><Y><A><I><G><I><D><K><R><N><S><V><E><D><Y><A><I><G><I><D><K><R><N><S><V><E><D><Y><A><I><G><I><D><K><R><N><T><V><E><D><Y><A><I><G><I><D><K><R><N><S><V><E><D><Y><A... | Ribosomally synthesized cyclic peptide ustiloxin B precursor: Part of the gene cluster that mediates the biosynthesis of the secondary metabolite ustiloxin B, an antimitotic tetrapeptide . The ustA translated product contains a 16-fold repeated peptide embedding the tetrapeptide Tyr-Ala-Ile-Gly, that is converted into ... | B8NM66 |
A4XLR9 | RL24_CALS8 | 50S ribosomal protein L24 | Caldicellulosiruptor | <M><P><N><K><V><H><V><K><K><G><D><T><V><V><V><I><S><G><K><Y><K><G><K><Q><G><K><V><L><T><V><L><P><K><D><K><K><V><V><V><E><G><V><N><I><V><K><K><H><V><R><P><N><P><K><M><P><Q><G><G><I><I><T><Q><E><A><P><I><W><A><C><K><V><M><L><V><C><P><K><C><N><K><P><T><R><I><G><H><R><F><I><Q><E><G><E><E><E><K><K><V><R><T><C><K><K><C><G><E... | One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.<BOP> | A4XLR9 |
Q5Z620 | CKX10_ORYSJ | Cytokinin oxidase 10 | Oryza sativa | <M><M><P><R><A><Q><L><T><T><F><L><I><V><T><S><F><L><S><T><V><P><Y><L><R><A><P><V><H><G><G><V><L><T><S><Y><D><V><S><S><L><D><I><M><S><K><I><H><T><D><H><D><A><T><T><K><A><S><S><D><F><G><H><I><V><H><A><T><P><N><G><V><F><R><P><T><F><P><A><D><I><A><A><L><I><R><L><S><L><S><Q><P><T><P><F><T><V><A><P><R><G><K><G><H><S><S><R><G... | Catalyzes the oxidation of cytokinins, a family of N(6)-substituted adenine derivatives that are plant hormones, where the substituent is an isopentenyl group.<BOP> | Q5Z620 |
Q8CQD2 | BUTA_STAES | Meso-2,3-butanediol dehydrogenase | Staphylococcus | <M><S><K><T><A><I><I><T><G><A><A><G><G><L><G><K><G><I><A><E><R><L><A><N><D><G><F><N><I><V><L><Q><D><I><N><E><A><L><L><L><E><T><E><K><E><F><K><E><K><G><Y><Q><A><V><A><Y><K><S><D><V><S><K><K><K><E><Q><E><E><L><V><Q><F><A><V><T><E><F><G><Q><L><D><V><M><V><N><N><A><G><V><D><A><V><T><P><I><L><E><I><G><E><E><E><L><S><K><L><F... | Catalyzes the irreversible reduction of 2,3-butanediol to (S)-acetoin in the presence of NADH.<BOP> | Q8CQD2 |
B2RV13 | CF97D_HUMAN | CFAP97 domain-containing protein 1 | Homo | <M><N><N><S><L><D><Y><L><A><Y><P><V><I><V><S><N><H><R><Q><S><T><T><F><R><K><K><L><D><F><G><H><Y><V><S><H><K><N><R><I><Q><I><A><K><P><T><V><D><T><K><P><P><V><A><H><T><N><H><I><L><K><L><S><K><L><Q><G><E><Q><K><K><I><N><K><I><E><Y><E><N><K><Q><L><C><Q><K><I><A><N><A><H><R><G><P><A><K><V><D><C><W><N><E><Y><F><S><K><S><L><N... | Required for male fertility through its role in axonemal doublet stabilization which is essential for sperm motility and fertilization.<BOP> | B2RV13 |
A4JCN6 | MOBA_BURVG | Molybdopterin-guanine dinucleotide synthase | Burkholderia cepacia complex | <M><P><A><S><V><T><P><S><I><T><G><L><L><L><A><G><G><R><A><T><R><M><D><G><A><D><K><G><L><Q><L><L><D><G><T><P><L><A><L><H><V><L><R><R><L><A><G><Q><V><D><E><M><V><I><S><A><N><R><N><A><D><R><Y><A><E><L><G><A><P><F><G><A><R><V><V><P><D><E><T><L><D><F><A><G><P><L><A><G><L><L><A><G><M><R><A><A><R><A><P><L><V><V><C><A><P><C><D... | Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo-MPT) cofactor (Moco or molybdenum cofactor) to form Mo-molybdopterin guanine dinucleotide (Mo-MGD) cofactor.<BOP> | A4JCN6 |
Q9C8J7 | TRO_ARATH | Protein ASH2 RELATIVE | Arabidopsis | <M><E><S><L><Q><S><N><S><K><I><E><E><A><E><Q><N><P><K><I><E><E><A><Q><V><S><V><S><L><P><E><E><P><T><G><V><L><L><P><S><E><L><V><D><D><S><A><P><P><E><S><S><D><A><V><E><E><S><I><E><T><A><S><E><A><E><V><S><I><S><L><L><E><G><T><T><T><G><T><A><L><L><P><S><E><E><N><D><L><A><P><L><E><S><S><G><I><I><E><E><P><I><D><T><D><L><E><K... | Trithorax-group gene homolog required for early embryogenesis . Required for the expression of FLC and FLC homologs and represses flowering . Required for proper leaf growth and development . Part of COMPASS-like complexes responsible for H3K4 trimethylation, but not for di- or mono-methylation of histone H3 'Lys-4' . ... | Q9C8J7 |
Q2JT84 | FOLD_SYNJA | Methenyltetrahydrofolate cyclohydrolase | unclassified Synechococcus | <M><S><A><K><I><L><D><G><K><A><L><A><G><R><L><Q><A><E><M><A><A><Q><V><Q><A><W><L><P><R><V><G><R><P><P><G><L><A><V><L><R><V><G><E><D><P><A><S><A><A><Y><V><R><G><K><E><R><A><C><E><R><V><G><I><A><S><F><G><R><H><F><S><A><Q><D><S><P><A><H><L><L><D><A><I><A><Q><L><N><Q><D><E><R><V><D><G><I><L><V><Q><L><P><L><P><P><G><W><D><P... | Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.<BOP> | Q2JT84 |
P34721 | MT1B_MORBO | Modification methylase MboIC | Moraxella | <M><R><I><K><P><Y><F><E><S><D><D><K><N><F><N><I><Y><Q><G><N><C><I><D><F><M><S><H><F><Q><D><N><S><I><D><M><I><F><A><D><P><P><Y><F><L><S><N><D><G><L><T><F><K><N><S><I><I><Q><S><V><N><K><G><E><W><D><K><N><D><N><E><A><S><I><Y><N><F><N><H><E><W><I><A><Q><A><R><Q><L><L><K><D><N><G><T><I><W><I><S><G><T><H><H><N><I><F><T><V><G... | A beta subtype methylase that recognizes the double-stranded sequence 5'-GATC-3', methylates A-2 on both strands, and protects the DNA from cleavage by the MboI endonuclease (Probable). This seems to be a weaker methylase than M1.MboI (Probable).<BOP> | P34721 |
B4U194 | CODY_STREM | GTP-sensing transcriptional pleiotropic repressor CodY | Streptococcus | <M><P><N><L><L><Q><K><T><R><K><I><T><S><I><L><Q><R><S><V><D><S><L><E><T><E><L><P><Y><N><T><M><A><S><R><L><A><D><I><I><D><C><N><A><C><I><I><N><G><G><G><S><L><L><G><Y><A><M><K><Y><K><T><N><T><D><R><V><E><E><F><F><E><T><R><Q><F><P><D><A><Y><V><K><A><A><S><R><V><Y><D><T><E><A><N><L><S><V><E><N><E><L><T><I><F><P><V><E><S><K... | DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer b... | B4U194 |
A6VHD2 | RL3_METM7 | 50S ribosomal protein L3 | Methanococcus | <M><G><M><K><K><S><R><P><R><R><G><S><L><A><F><S><P><R><K><R><A><K><K><L><V><P><K><I><R><S><W><P><A><D><K><K><V><G><L><Q><A><F><P><V><Y><K><A><G><T><T><H><A><L><L><I><E><N><N><P><K><S><P><N><N><G><Q><E><V><F><T><P><V><T><V><L><E><T><P><D><V><T><V><A><G><I><R><L><Y><E><K><T><T><K><G><L><K><A><L><T><E><V><W><A><E><Q><L><D... | One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.<BOP> | A6VHD2 |
Q8KIX1 | CH60_BUCTT | Chaperonin-60 | Buchnera | <M><A><A><K><E><V><K><F><G><N><D><A><R><A><K><M><L><R><G><V><N><V><L><A><D><A><V><K><V><T><L><G><P><K><G><R><N><V><V><L><D><K><S><F><G><A><P><T><I><T><K><D><G><V><S><V><A><R><E><I><E><L><E><D><K><F><E><N><M><G><T><Q><M><V><K><E><V><A><S><K><A><N><D><A><A><G><D><G><T><T><T><A><T><V><L><A><Q><S><I><I><T><E><G><L><K><A><V... | Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.<BOP> | Q8KIX1 |
A5F6Z2 | FADR_VIBC3 | Fatty acid metabolism regulator protein | Vibrio | <M><V><I><K><A><K><S><P><A><G><F><A><E><K><Y><I><I><E><S><I><W><N><G><R><F><P><P><G><S><I><L><P><A><E><R><E><L><S><E><L><I><G><V><T><R><T><T><L><R><E><V><L><Q><R><L><A><R><D><G><W><L><T><I><Q><H><G><K><P><T><K><V><N><Q><F><M><E><T><S><G><L><H><I><L><D><T><L><M><T><L><D><A><E><N><A><T><S><I><V><E><D><L><L><A><A><R><T><N... | Multifunctional regulator of fatty acid metabolism.<BOP> | A5F6Z2 |
B0T734 | RPIA_CAUSK | Phosphoriboisomerase A | unclassified Caulobacter | <M><S><A><D><D><Q><K><R><I><S><G><E><A><A><A><E><L><V><E><A><G><M><V><V><G><L><G><T><G><S><T><A><A><W><F><V><K><A><L><A><A><R><K><L><D><I><R><G><V><P><T><S><E><A><T><A><N><L><A><R><E><L><G><I><A><L><T><A><L><D><D><V><K><S><I><D><L><T><V><D><G><A><D><E><I><G><P><G><L><S><L><I><K><G><G><G><A><A><L><L><R><E><K><L><V><W><E... | Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate.<BOP> | B0T734 |
Q9H1E3 | NUCKS_HUMAN | P1 | Homo | <M><S><R><P><V><R><N><R><K><V><V><D><Y><S><Q><F><Q><E><S><D><D><A><D><E><D><Y><G><R><D><S><G><P><P><T><K><K><I><R><S><S><P><R><E><A><K><N><K><R><R><S><G><K><N><S><Q><E><D><S><E><D><S><E><D><K><D><V><K><T><K><K><D><D><S><H><S><A><E><D><S><E><D><E><K><E><D><H><K><N><V><R><Q><Q><R><Q><A><A><S><K><A><A><S><K><Q><R><E><M><L... | Chromatin-associated protein involved in DNA repair by promoting homologous recombination (HR) . Binds double-stranded DNA (dsDNA) and secondary DNA structures, such as D-loop structures, but with less affinity than RAD51AP1 .<BOP> | Q9H1E3 |
Q5PCV8 | PDXB_SALPA | Erythronate-4-phosphate dehydrogenase | Salmonella | <M><K><I><L><V><D><E><N><M><P><Y><A><R><E><L><F><S><R><L><G><E><V><K><A><V><P><G><R><P><I><P><V><E><E><L><N><H><A><D><A><L><M><V><R><S><V><T><K><V><N><E><S><L><L><S><G><T><P><I><N><F><V><G><T><A><T><A><G><T><D><H><V><D><E><A><W><L><K><Q><A><G><I><G><F><S><A><A><P><G><C><N><A><I><A><V><V><E><Y><V><F><S><A><L><L><M><L><A... | Catalyzes the oxidation of erythronate-4-phosphate to 3-hydroxy-2-oxo-4-phosphonooxybutanoate.<BOP> | Q5PCV8 |
Q9NFL4 | HCYG_APHSP | Hemocyanin G chain | unclassified Aphonopelma | <M><A><S><I><P><E><K><Q><A><L><I><L><P><L><F><E><K><L><T><S><L><T><K><E><T><P><P><R><A><Q><W><D><P><R><L><A><G><V><G><V><L><P><R><G><T><L><F><S><C><F><H><E><K><H><L><L><E><A><T><K><L><F><K><V><L><Y><S><P><E><S><F><N><D><F><L><Q><L><A><R><E><A><R><V><V><V><N><E><G><L><F><A><Y><A><F><S><V><A><V><I><H><R><D><D><C><K><G><V... | Hemocyanins are copper-containing oxygen carriers occurring freely dissolved in the hemolymph of many mollusks and arthropods.<BOP> | Q9NFL4 |
Q0A4M2 | ATP6_ALKEH | F-ATPase subunit 6 | Alkalilimnicola | <M><S><G><N><T><A><L><D><Y><I><Q><H><H><L><T><N><L><A><V><G><E><G><Y><W><T><F><H><V><D><S><L><I><M><S><F><S><L><G><A><L><F><C><Y><L><F><W><L><G><A><R><R><A><T><A><G><V><P><S><G><L><Q><N><F><V><E><L><M><V><E><F><V><D><Q><T><T><R><E><T><F><Q><G><K><S><R><L><I><A><P><L><A><L><T><I><F><C><W><I><F><L><M><N><L><M><D><L><V><P... | Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.<BOP> | Q0A4M2 |
B3EIU4 | MIAA_CHLL2 | Isopentenyl-diphosphate:tRNA isopentenyltransferase | Chlorobium | <M><T><S><G><E><R><Q><K><P><V><L><V><I><L><G><P><T><A><S><G><K><S><A><L><A><M><N><I><A><G><N><L><D><A><E><I><I><S><A><D><S><R><Q><I><Y><R><E><L><T><I><G><S><A><K><P><S><E><D><D><L><R><M><V><R><H><H><F><I><N><E><K><T><I><G><E><P><F><T><A><G><D><F><A><E><A><A><Y><A><R><I><L><D><I><H><N><R><N><K><Y><A><V><V><V><G><G><S><T... | Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).<BOP> | B3EIU4 |
A4QQN1 | M2DH_MAGO7 | Mannitol 2-dehydrogenase | Pyricularia | <M><A><F><K><L><S><T><K><H><L><A><D><I><G><A><Q><T><E><K><S><I><R><I><P><S><Y><D><R><N><D><V><K><E><G><I><V><H><V><G><V><G><G><F><H><R><A><H><L><A><V><Y><V><D><K><L><M><Q><S><H><G><V><R><D><Y><A><I><C><G><V><G><L><Q><P><A><D><A><S><M><R><D><V><L><A><S><Q><D><H><M><Y><T><V><I><E><R><S><A><A><G><S><T><A><H><V><V><G><S><I... | Catalyzes the NAD(H)-dependent interconversion of D-fructose and D-mannitol in the mannitol metabolic pathway.<BOP> | A4QQN1 |
Q3J8T7 | RS4_NITOC | 30S ribosomal protein S4 | Nitrosococcus | <M><A><K><Y><T><G><P><K><L><K><Q><A><R><R><E><G><T><D><L><F><L><K><S><G><V><R><P><I><D><S><K><C><K><I><E><Q><V><P><G><Q><H><G><A><G><A><R><R><A><R><M><S><D><Y><A><L><Q><L><R><E><K><Q><K><L><R><R><M><Y><G><V><L><E><R><Q><F><R><R><Y><Y><K><E><A><A><R><R><K><G><S><T><G><E><N><L><L><K><L><L><E><S><R><L><D><N><V><V><Y><R><M... | With S5 and S12 plays an important role in translational accuracy.<BOP> | Q3J8T7 |
A9WNC6 | ATPA_RENSM | F-ATPase subunit alpha | Renibacterium | <M><A><E><L><T><I><N><A><D><D><V><R><N><A><L><N><E><F><A><A><S><Y><E><P><G><N><A><E><R><V><E><V><G><R><V><T><T><A><S><D><G><I><A><R><V><E><G><L><P><S><V><M><A><N><E><L><L><R><F><E><D><G><T><L><G><L><A><Q><N><L><D><V><R><E><I><G><V><I><I><L><G><D><F><T><G><I><E><E><G><Q><E><V><H><R><T><G><E><I><L><S><V><P><V><G><D><Q><F... | Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit.<BOP> | A9WNC6 |
Q6F8I7 | PTH_ACIAD | Peptidyl-tRNA hydrolase | Acinetobacter | <M><S><K><I><S><L><I><V><G><L><G><N><P><G><A><E><Y><A><Q><T><R><H><N><A><G><F><W><F><V><E><Q><L><A><D><R><Y><N><I><T><L><K><K><D><P><K><F><H><G><F><S><G><R><G><Q><I><E><G><H><D><V><R><L><L><I><P><T><T><F><M><N><R><S><G><Q><S><V><V><P><F><S><K><F><Y><Q><I><S><P><E><A><I><L><I><A><H><D><E><L><D><M><D><P><G><V><I><R><L><K... | The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.<BOP> | Q6F8I7 |
A9M5C1 | CLPX_BRUC2 | ATP-dependent Clp protease ATP-binding subunit ClpX | Brucella | <M><S><K><V><S><N><G><G><G><D><S><K><N><T><L><Y><C><S><F><C><G><K><S><Q><H><E><V><R><K><L><I><A><G><P><T><V><F><I><C><D><E><C><V><E><L><C><M><D><I><I><R><E><E><N><K><S><S><M><V><K><S><R><E><G><V><P><T><P><Q><E><I><M><A><V><L><D><D><Y><V><I><G><Q><K><D><A><K><R><V><L><S><V><A><V><H><N><H><Y><K><R><L><A><H><Q><S><K><N><S... | ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.<BOP> | A9M5C1 |
A7FKS8 | SSRP_YERP3 | Small protein B | Yersinia | <M><T><K><K><K><A><Y><K><P><G><S><A><T><I><A><Q><N><K><R><A><R><H><E><Y><F><I><E><E><E><F><E><A><G><L><A><L><Q><G><W><E><V><K><S><L><R><A><G><K><A><N><I><S><D><S><Y><V><M><F><K><N><G><E><A><F><L><F><G><A><T><I><T><P><L><N><V><A><S><T><H><V><V><C><E><P><M><R><T><R><K><L><L><L><N><K><R><E><L><D><S><L><F><G><R><V><N><R><E... | Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemb... | A7FKS8 |
Q5N7W3 | RPN2_ORYSJ | Ribophorin-2 | Oryza sativa | <M><A><A><A><G><G><L><P><A><S><A><T><L><L><L><L><V><I><A><A><V><A><V><A><P><L><A><S><A><V><R><P><V><S><D><A><H><R><S><A><A><A><E><L><F><A><A><S><P><D><G><S><F><G><D><L><E><T><T><Y><E><A><V><R><T><F><Q><I><L><G><V><E><K><D><K><G><L><I><G><K><A><C><K><F><A><A><E><K><L><A><S><S><S><S><S><P><A><K><D><L><F><H><A><A><R><I><S... | Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol-pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-... | Q5N7W3 |
Q2G8X0 | RL14_NOVAD | 50S ribosomal protein L14 | Novosphingobium | <M><I><Q><M><Q><S><N><L><D><V><A><D><N><S><G><A><K><R><V><Q><C><I><K><V><L><G><G><S><K><R><R><F><A><G><V><G><D><I><I><V><V><S><V><K><E><A><Q><P><R><A><R><V><K><K><G><D><V><H><R><A><V><I><V><R><T><K><K><D><V><R><R><T><D><G><S><V><I><R><F><D><S><N><A><A><V><L><V><G><K><N><E><E><P><I><G><T><R><I><F><G><P><V><V><R><E><L><R... | Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.<BOP> | Q2G8X0 |
Q92765 | SFRP3_HUMAN | FrzB-1 | Homo | <M><V><C><G><S><P><G><G><M><L><L><L><R><A><G><L><L><A><L><A><A><L><C><L><L><R><V><P><G><A><R><A><A><A><C><E><P><V><R><I><P><L><C><K><S><L><P><W><N><M><T><K><M><P><N><H><L><H><H><S><T><Q><A><N><A><I><L><A><I><E><Q><F><E><G><L><L><G><T><H><C><S><P><D><L><L><F><F><L><C><A><M><Y><A><P><I><C><T><I><D><F><Q><H><E><P><I><K><P... | Soluble frizzled-related proteins (sFRPS) function as modulators of Wnt signaling through direct interaction with Wnts. They have a role in regulating cell growth and differentiation in specific cell types. SFRP3/FRZB appears to be involved in limb skeletogenesis. Antagonist of Wnt8 signaling. Regulates chondrocyte mat... | Q92765 |
Q8CWW3 | RUVA_STRMU | Holliday junction ATP-dependent DNA helicase RuvA | Streptococcus | <M><Y><D><Y><I><K><G><N><L><T><K><I><T><A><K><Y><I><V><L><E><T><G><G><L><G><Y><V><I><N><V><A><N><P><Y><S><F><S><N><Q><I><N><Q><A><I><Q><I><Y><I><H><H><V><V><R><E><D><A><H><L><L><Y><G><F><H><T><E><D><E><K><A><V><F><L><N><L><I><S><V><S><G><I><G><P><T><S><A><L><A><I><I><A><A><D><D><N><E><G><L><V><K><A><I><D><H><S><D><V><N... | The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA... | Q8CWW3 |
C4ZBF3 | RBFA_AGARV | Ribosome-binding factor A | Lachnospiraceae incertae sedis | <M><R><K><N><S><I><K><N><I><R><I><N><E><E><V><M><R><E><L><S><N><I><I><R><G><E><I><K><D><P><R><I><N><P><M><T><S><V><V><A><V><E><V><A><P><D><L><K><T><A><K><A><Y><I><S><V><L><G><D><K><K><S><Q><A><D><T><L><A><G><L><K><S><A><E><G><Y><I><R><R><T><L><A><K><N><I><N><L><R><N><T><P><A><I><T><F><I><I><D><Q><S><I><E><Y><G><V><E><M... | One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal heli... | C4ZBF3 |
Q9XQN8 | RPOA_SINAL | Plastid-encoded RNA polymerase subunit alpha | Sinapis | <M><V><R><E><K><V><K><V><S><T><R><T><L><Q><W><K><C><V><E><S><R><R><D><S><K><R><L><Y><Y><G><R><F><I><L><S><P><L><M><K><G><Q><A><D><T><I><G><I><A><M><A><R><A><L><L><G><E><I><E><G><T><C><I><T><R><A><K><S><E><N><I><P><H><D><Y><S><N><I><V><G><I><Q><E><S><V><H><E><I><L><M><N><L><N><E><I><V><L><K><S><N><L><Y><G><T><R><N><P><F... | DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.<BOP> | Q9XQN8 |
Q1CTU9 | FOLD_HELPH | Methenyltetrahydrofolate cyclohydrolase | Helicobacter | <M><P><N><R><G><V><V><L><L><D><G><Q><A><L><A><Y><D><I><E><K><D><L><K><N><K><I><Q><T><I><T><A><Q><T><H><K><R><P><K><L><A><V><I><L><V><G><K><D><P><A><S><I><T><Y><V><N><M><K><I><K><A><C><Q><R><V><G><M><D><F><D><L><K><T><L><Q><E><D><I><T><E><A><K><L><L><S><L><I><K><D><Y><N><T><D><Q><N><I><S><G><V><L><V><Q><L><P><L><P><R><H... | Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.<BOP> | Q1CTU9 |
Q3ZCC9 | SEC13_BOVIN | SEC13-like protein 1 | Bos | <M><V><S><V><I><N><T><V><D><T><S><H><E><D><M><I><H><D><A><Q><M><D><Y><Y><G><T><R><L><A><T><C><S><S><D><R><S><V><K><I><F><D><V><R><N><G><G><Q><I><L><V><A><D><L><R><G><H><E><G><P><V><W><Q><V><A><W><A><H><P><M><Y><G><N><I><L><A><S><C><S><Y><D><R><K><V><I><I><W><K><E><E><N><G><T><W><E><K><T><H><E><H><T><G><H><D><S><S><V><N... | As a component of the GATOR subcomplex GATOR2, functions within the amino acid-sensing branch of the TORC1 signaling pathway. Indirectly activates mTORC1 and the TORC1 signaling pathway through the inhibition of the GATOR1 subcomplex. It is negatively regulated by the upstream amino acid sensors SESN2 and CASTOR1.<BOP> | Q3ZCC9 |
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