accession
stringlengths
6
10
name
stringlengths
6
11
Full Name
stringlengths
1
147
taxon
stringlengths
3
46
sequence
stringlengths
48
2.3k
function
stringlengths
11
1.34k
AlphaFoldDB
stringlengths
6
10
Q9ZLY1
MRAY_HELPJ
UDP-MurNAc-pentapeptide phosphotransferase
Helicobacter
<M><L><Y><S><L><L><Y><G><Y><F><N><I><N><L><F><Q><Y><L><T><F><R><A><G><L><G><F><F><I><A><F><F><L><T><L><F><L><M><P><K><F><I><L><W><A><K><A><K><K><A><N><Q><P><I><S><S><F><V><P><S><H><Q><N><K><K><D><T><P><T><M><G><G><I><V><F><V><F><A><T><I><V><A><S><V><L><C><A><S><L><S><N><L><Y><V><L><L><G><I><I><V><L><V><G><F><S><F><V><G...
Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I...
Q9ZLY1
Q6DJ00
OSTCN_XENTR
Gamma-carboxyglutamic acid-containing protein
Silurana
<M><K><L><A><I><V><L><L><L><L><G><L><A><V><L><C><L><G><G><K><D><S><Q><H><S><A><S><A><G><D><S><R><S><S><E><A><F><I><S><R><Q><D><S><A><N><F><A><R><R><H><K><R><S><Y><R><Y><N><V><A><R><G><A><A><V><T><S><P><L><E><S><Q><R><E><V><C><E><L><N><P><D><C><D><E><L><A><D><H><I><G><F><Q><E><A><Y><R><R><F><Y><G><P><V>
Binds strongly to apatite and calcium.<BOP>
Q6DJ00
Q2MF16
DOIS_STRSD
2-deoxy-scyllo-inosose synthase
Streptoalloteichus
<M><Q><T><T><T><I><T><M><G><D><V><Q><Y><P><Y><R><L><G><T><G><C><V><D><G><I><V><T><R><L><G><E><L><E><A><S><H><Y><L><V><L><C><D><A><T><V><A><E><L><Y><G><H><D><L><A><A><R><L><R><R><S><A><G><P><A><S><V><L><T><H><P><A><G><E><E><H><K><G><L><G><T><L><D><T><L><A><D><A><A><L><H><A><G><V><D><R><R><G><V><V><V><A><L><G><G><G><V><T...
Catalyzes the intramolecular carbocycle formation from D-glucose-6-phosphate to 2-deoxy-scyllo-inosose (DOI).<BOP>
Q2MF16
A8G6V2
ATPD_PROM2
F-type ATPase subunit delta
Prochlorococcus
<M><P><L><L><N><S><V><T><T><P><Y><A><E><A><L><L><Q><V><V><N><E><N><L><Q><T><E><E><M><V><S><E><V><K><Q><L><L><E><L><I><N><D><S><P><E><L><E><K><A><L><S><S><P><I><L><E><T><D><A><K><K><K><I><I><I><E><I><F><S><N><K><V><N><S><S><L><M><N><F><L><K><L><L><A><D><R><Q><R><I><G><I><L><T><S><I><L><E><R><F><L><E><I><Y><R><E><N><S><N...
This protein is part of the stalk that links CF(0) to CF(1). It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.<BOP>
A8G6V2
B0S1J2
QUEA_FINM2
Queuosine biosynthesis protein QueA
Finegoldia
<M><N><T><D><D><F><D><Y><E><L><D><E><K><F><I><A><Q><T><P><L><D><K><R><D><E><S><K><L><M><V><M><D><R><F><N><G><N><T><E><I><K><K><F><Y><N><I><I><D><Y><L><N><P><G><D><V><L><V><C><N><N><T><R><V><I><P><A><R><L><F><G><H><R><P><E><K><E><E><K><I><E><V><L><L><L><Q><Q><T><E><D><K><W><E><C><L><V><K><P><G><K><K><M><K><L><N><Q><V><I...
Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA).<BOP>
B0S1J2
B3QYB6
QUEF_CHLT3
PreQ(0) reductase
Chloroherpeton
<M><K><P><E><L><L><E><T><F><E><N><Q><Y><P><N><R><D><Y><T><I><E><I><V><N><P><E><F><T><S><V><C><P><K><T><G><L><P><D><F><G><T><I><T><L><Q><Y><I><P><N><K><L><C><V><E><L><K><S><L><K><Y><Y><Y><L><E><F><R><N><A><G><I><F><Y><E><N><V><T><N><K><I><L><D><D><L><V><K><A><V><K><P><K><E><M><K><I><I><S><E><W><K><A><R><G><G><I><T><T><T...
Catalyzes the NADPH-dependent reduction of 7-cyano-7-deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1).<BOP>
B3QYB6
A6WY74
RUVC_BRUA4
Holliday junction resolvase RuvC
Brucella
<M><K><E><T><I><R><I><I><G><I><D><P><G><L><R><R><T><G><W><G><I><V><E><S><L><G><N><S><L><H><F><I><G><S><G><T><V><T><S><N><A><E><M><D><L><A><S><R><L><C><Q><L><H><E><G><L><S><K><V><L><H><E><Y><M><P><H><E><A><A><V><E><H><T><F><V><N><K><D><A><T><A><T><L><K><L><G><Q><A><R><G><I><A><L><L><A><P><A><Q><A><G><L><P><V><A><E><Y><A...
Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group.<BOP>
A6WY74
Q8DHJ2
PSBZ_THEVB
Photosystem II reaction center protein Z
Thermosynechococcus
<M><T><I><L><F><Q><L><A><L><A><A><L><V><I><L><S><F><V><M><V><I><G><V><P><V><A><Y><A><S><P><Q><D><W><D><R><S><K><Q><L><I><F><L><G><S><G><L><W><I><A><L><V><L><V><V><G><V><L><N><F><F><V><V>
Controls the interaction of photosystem II (PSII) cores with the light-harvesting antenna. May also aid in binding of PsbK, Ycf12 and the oxygen-evolving complex to PSII, at least in vitro. PSII is a light-driven water plastoquinone oxidoreductase, using light energy to abstract electrons from H(2)O, generating a proto...
Q8DHJ2
P58779
SCX5_CENSC
Alpha-like toxin CsEv5
Centruroides
<K><D><G><Y><P><V><D><S><K><G><C><K><L><S><C><V><A><N><N><Y><C><D><N><Q><C><K><M><K><K><A><S><G><G><H><C><Y><A><M><S><C><Y><C><E><G><L><P><E><N><A><K><V><S><D><S><A><T><N><I><C>
Binds voltage-independently sodium channels (Nav) and inhibits the inactivation of the activated channels, thereby blocking neuronal transmission. Is highly toxic to insects and barely toxic to mammals. As it does not compete with the classical alpha-toxin AaH2, this toxin is considered as an alpha-like toxin.<BOP>
P58779
Q979T2
RS10_THEVO
30S ribosomal protein S10
Thermoplasma
<M><A><S><Y><K><A><R><I><S><L><S><G><T><E><H><K><I><V><D><M><V><C><S><E><I><K><E><I><A><S><R><T><G><V><E><I><H><G><P><M><P><L><P><T><K><K><L><V><V><P><V><R><K><S><P><D><G><E><G><T><N><T><W><D><H><W><E><M><R><I><H><K><R><L><I><D><V><D><A><D><E><R><T><L><R><Q><L><M><R><I><P><I><P><D><G><V><Q><I><E><I><Q><I><K><S>
Involved in the binding of tRNA to the ribosomes.<BOP>
Q979T2
Q5RCW7
KLD8B_PONAB
Kelch domain-containing protein 8B
Pongo
<M><S><A><G><G><G><R><A><F><A><W><Q><V><F><P><P><M><P><T><C><R><V><Y><G><T><V><A><H><Q><D><E><H><L><L><V><L><G><G><C><G><R><A><G><L><P><L><D><T><A><E><T><L><D><M><A><S><H><T><W><L><A><L><A><P><L><P><T><A><R><A><G><A><A><A><V><V><L><G><K><Q><V><L><V><V><G><G><V><D><E><V><Q><S><P><V><A><A><V><E><A><F><L><M><D><E><G><R><W...
Involved in pinching off the separated nuclei at the cleavage furrow and in cytokinesis. Required for mitotic integrity and maintenance of chromosomal stability. Protects cells against mitotic errors, centrosomal amplification, micronucleus formation and aneuploidy. Plays a key role of midbody function involving abscis...
Q5RCW7
A5K5W9
ASNA_PLAVS
Arsenite-stimulated ATPase
Plasmodium (Plasmodium)
<M><S><D><A><D><S><L><S><C><S><L><T><L><E><S><D><E><Y><D><E><E><E><Y><D><T><N><L><S><K><L><L><E><N><K><T><L><N><W><I><F><V><G><G><K><G><G><V><G><K><T><T><T><S><C><S><I><A><V><Q><L><A><K><R><R><E><S><V><L><L><L><S><T><D><P><A><H><N><T><S><D><A><F><N><Q><K><F><T><N><Q><P><T><L><I><N><S><F><D><N><L><Y><C><M><E><I><D><T><T...
ATPase required for the post-translational delivery of tail-anchored (TA) proteins to the endoplasmic reticulum. Recognizes and selectively binds the transmembrane domain of TA proteins in the cytosol. This complex then targets to the endoplasmic reticulum by membrane-bound receptors, where the tail-anchored protein is...
A5K5W9
P00171
CYB5_BOVIN
Cytochrome b5
Bos
<M><A><E><E><S><S><K><A><V><K><Y><Y><T><L><E><E><I><Q><K><H><N><N><S><K><S><T><W><L><I><L><H><Y><K><V><Y><D><L><T><K><F><L><E><E><H><P><G><G><E><E><V><L><R><E><Q><A><G><G><D><A><T><E><N><F><E><D><V><G><H><S><T><D><A><R><E><L><S><K><T><F><I><I><G><E><L><H><P><D><D><R><S><K><I><T><K><P><S><E><S><I><I><T><T><I><D><S><N><P...
Cytochrome b5 is a membrane-bound hemoprotein functioning as an electron carrier for several membrane-bound oxygenases.<BOP>
P00171
Q9Z2I8
SUCB2_MOUSE
Succinyl-CoA synthetase beta-G chain
Mus
<M><A><S><P><V><A><I><A><A><Q><A><G><K><L><L><R><E><R><A><L><R><P><L><L><A><V><R><S><Q><A><G><H><L><T><P><R><R><W><L><N><L><Q><E><Y><Q><S><K><K><L><M><S><E><H><G><V><R><V><Q><R><F><F><V><A><N><T><A><K><E><A><L><E><A><A><K><R><L><N><A><K><E><I><V><L><K><A><Q><I><L><A><G><G><R><G><K><G><V><F><N><S><G><L><K><G><G><V><H><L...
GTP-specific succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate...
Q9Z2I8
P24794
COX1_BETVU
Cytochrome c oxidase polypeptide I
Beta
<M><T><N><L><V><R><W><L><F><S><T><N><H><K><D><I><G><T><L><Y><F><I><F><G><A><I><A><G><V><M><G><T><C><F><S><V><L><I><R><M><E><L><A><R><P><G><D><Q><I><L><G><G><N><H><Q><L><Y><N><V><L><I><T><A><H><A><F><L><M><I><F><F><M><V><M><P><A><M><I><G><G><F><G><N><W><F><V><P><I><L><I><G><A><P><D><M><A><F><P><R><L><N><N><I><S><F><W><L...
Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CII...
P24794
Q9KS43
TSEL_VIBCH
Toxin TseL
Vibrio
<M><D><S><F><N><Y><C><V><Q><C><N><P><E><E><N><W><L><E><L><E><F><R><S><E><N><D><E><P><I><D><G><L><L><V><T><I><T><N><Q><S><A><P><S><N><T><Y><T><Q><T><T><S><S><G><K><V><L><F><G><K><I><A><A><G><E><W><R><A><S><V><S><Q><A><S><L><L><T><E><V><E><K><Y><A><S><R><K><E><G><Q><E><S><P><V><K><K><R><A><A><A><E><L><D><A><A><D><K><D><T...
Toxin secreted by the type VI (T6SS) secretion system that acts on prokaryotic as well as eukaryotic target cells.<BOP>
Q9KS43
A5F5Y6
NQRD_VIBC3
NQR-1 subunit D
Vibrio
<M><S><S><A><K><E><L><K><K><S><V><L><A><P><V><L><D><N><N><P><I><A><L><Q><V><L><G><V><C><S><A><L><A><V><T><T><K><L><E><T><A><F><V><M><T><L><A><V><M><F><V><T><A><L><S><N><F><F><V><S><L><I><R><N><H><I><P><N><S><V><R><I><I><V><Q><M><A><I><I><A><S><L><V><I><V><V><D><Q><I><L><K><A><Y><L><Y><D><I><S><K><Q><L><S><V><F><V><G><L...
NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol.<BOP>
A5F5Y6
P20108
PRDX3_MOUSE
Thioredoxin-dependent peroxiredoxin 3
Mus
<M><A><A><A><A><G><R><L><L><W><S><S><V><A><R><H><A><S><A><I><S><R><S><I><S><A><S><T><V><L><R><P><V><A><S><R><R><T><C><L><T><D><I><L><W><S><A><S><A><Q><G><K><S><A><F><S><T><S><S><S><F><H><T><P><A><V><T><Q><H><A><P><Y><F><K><G><T><A><V><V><N><G><E><F><K><E><L><S><L><D><D><F><K><G><K><Y><L><V><L><F><F><Y><P><L><D><F><T><F...
Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.<BOP>
P20108
Q13ES7
UPPP_RHOPS
Undecaprenyl pyrophosphate phosphatase
Rhodopseudomonas
<M><L><F><D><I><F><R><A><V><I><L><G><V><V><E><G><V><T><E><F><L><P><V><S><S><T><G><H><L><L><L><V><G><R><F><F><N><L><G><E><D><S><F><W><K><S><F><A><V><L><I><Q><L><G><A><I><L><A><I><L><S><I><Y><F><A><K><L><W><R><I><A><L><G><M><F><S><D><P><A><A><R><R><F><V><I><G><V><L><V><A><F><L><P><A><A><M><I><G><A><V><A><G><S><Y><I><K><L...
Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin.<BOP>
Q13ES7
P51480
CDN2A_MOUSE
p16-INK4a
Mus
<M><E><S><A><A><D><R><L><A><R><A><A><A><Q><G><R><V><H><D><V><R><A><L><L><E><A><G><V><S><P><N><A><P><N><S><F><G><R><T><P><I><Q><V><M><M><M><G><N><V><H><V><A><A><L><L><L><N><Y><G><A><D><S><N><C><E><D><P><T><T><F><S><R><P><V><H><D><A><A><R><E><G><F><L><D><T><L><V><V><L><H><G><S><G><A><R><L><D><V><R><D><A><W><G><R><L><P><L...
Acts as a negative regulator of the proliferation of normal cells by interacting strongly with CDK4 and CDK6. This inhibits their ability to interact with cyclins D and to phosphorylate the retinoblastoma protein.<BOP>
P51480
A0A1L8GXY6
N4B3A_XENLA
NEDD4-binding protein 3-A
Xenopus
<M><A><A><A><Q><T><F><N><S><N><C><D><P><G><N><F><H><K><L><Q><S><F><P><S><E><S><V><T><Y><T><C><K><M><G><S><V><S><S><L><I><D><K><Q><D><F><P><H><D><G><F><N><L><D><F><K><P><F><P><E><P><N><C><K><R><G><L><H><Q><K><E><L><L><S><Y><L><N><I><T><K><K><E><V><K><S><N><K><K><F><H><S><G><L><G><F><R><R><E><H><S><V><E><G><G><E><N><D><Y...
Plays a role in axon and dendrite arborization during cranial nerve development . Also important for neural crest migration and early development of other anterior structures including eye, brain and cranial cartilage .<BOP>
A0A1L8GXY6
Q6YPW4
PYRG_ONYPE
UTP--ammonia ligase
Candidatus Phytoplasma asteris
<M><N><N><K><D><L><K><T><K><F><I><F><I><T><G><G><V><V><S><S><L><G><K><G><I><T><A><A><S><I><G><Q><I><L><K><N><R><G><L><K><V><S><I><Q><K><L><D><P><Y><I><N><I><D><P><G><T><M><S><P><Y><Q><H><G><E><V><F><V><T><D><D><G><A><E><T><D><L><D><L><G><H><Y><E><R><F><L><D><E><N><M><S><K><K><S><N><V><T><A><G><Q><I><Y><Q><S><V><I><N><K...
Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.<BOP>
Q6YPW4
A8ESW0
RS5_ALIB4
30S ribosomal protein S5
Aliarcobacter
<M><A><V><N><R><E><D><F><Q><E><A><I><V><K><I><G><R><V><T><K><V><V><K><G><G><R><R><F><R><F><T><A><L><V><V><V><G><D><K><N><G><T><V><G><F><G><T><G><K><A><K><E><V><P><D><A><I><K><K><A><L><D><D><A><F><K><S><L><V><T><V><S><I><K><G><T><T><I><A><H><D><I><E><H><K><Y><N><A><S><K><I><L><L><R><P><A><S><E><G><T><G><L><I><A><G><G><A...
Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.<BOP>
A8ESW0
A6TGQ0
THIE_KLEP7
Thiamine-phosphate pyrophosphorylase
Klebsiella
<M><Y><Q><P><D><F><P><P><V><P><F><R><L><G><L><Y><P><V><V><D><S><V><A><W><I><E><R><L><L><E><A><G><V><R><T><L><Q><L><R><I><K><D><R><R><D><S><E><V><E><D><D><V><I><A><A><I><A><L><G><R><R><Y><H><A><R><L><F><I><N><D><Y><W><Q><L><A><I><K><H><Q><A><Y><G><V><H><L><G><Q><E><D><L><E><T><T><D><L><S><A><I><R><Q><A><G><L><R><L><G><V...
Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP).<BOP>
A6TGQ0
Q5E8M1
FPG_ALIF1
DNA-(apurinic or apyrimidinic site) lyase MutM
Aliivibrio
<M><P><E><L><P><E><V><E><T><S><R><L><G><I><T><P><H><L><Q><G><Q><T><I><K><A><I><V><V><R><T><D><K><L><R><W><P><I><P><Q><E><L><Q><K><L><V><G><Q><R><V><Q><S><I><R><R><R><A><K><Y><L><M><I><D><T><P><K><G><S><A><I><I><H><L><G><M><S><G><S><L><R><V><L><D><E><E><V><P><S><A><K><H><D><H><V><D><L><V><L><E><N><G><K><V><L><R><Y><N><D...
Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. ...
Q5E8M1
A3DJ13
TSAD_ACET2
tRNA threonylcarbamoyladenosine biosynthesis protein TsaD
Acetivibrio
<M><K><D><I><L><I><L><G><I><E><T><S><C><D><E><T><S><A><S><V><V><K><N><G><R><Q><V><L><S><N><V><I><S><S><Q><V><A><L><H><Q><K><Y><G><G><V><V><P><E><I><A><S><R><K><H><V><E><L><I><M><P><V><I><H><Q><S><L><E><E><A><G><I><K><I><E><Q><V><D><A><I><G><V><T><Y><G><P><G><L><V><G><A><L><L><V><G><L><S><A><A><K><A><L><A><F><A><L><D><K...
Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct ca...
A3DJ13
P23594
PP2A1_YEAST
Serine/threonine-protein phosphatase PP2A-1 catalytic subunit
Saccharomyces
<M><D><T><D><L><D><V><P><M><Q><D><A><V><T><E><Q><L><T><P><T><V><S><E><D><M><D><L><N><N><N><S><S><D><N><N><A><E><E><F><S><V><D><D><L><K><P><G><S><S><G><I><A><D><H><K><S><S><K><P><L><E><L><N><N><T><N><I><N><Q><L><D><Q><W><I><E><H><L><S><K><C><E><P><L><S><E><D><D><V><A><R><L><C><K><M><A><V><D><V><L><Q><F><E><E><N><V><K><P...
Exact function not known, phosphatase 2A performs an essential cellular function.<BOP>
P23594
A0A0B4J240
TVA10_HUMAN
T cell receptor alpha variable 10
Homo
<M><K><K><H><L><T><T><F><L><V><I><L><W><L><Y><F><Y><R><G><N><G><K><N><Q><V><E><Q><S><P><Q><S><L><I><I><L><E><G><K><N><C><T><L><Q><C><N><Y><T><V><S><P><F><S><N><L><R><W><Y><K><Q><D><T><G><R><G><P><V><S><L><T><I><M><T><F><S><E><N><T><K><S><N><G><R><Y><T><A><T><L><D><A><D><T><K><Q><S><S><L><H><I><T><A><S><Q><L><S><D><S><A...
V region of the variable domain of T cell receptor (TR) alpha chain that participates in the antigen recognition . Alpha-beta T cell receptors are antigen specific receptors which are essential to the immune response and are present on the cell surface of T lymphocytes. Recognize peptide-major histocompatibility (MH) (...
A0A0B4J240
Q7SDH9
PSF1_NEUCR
DNA replication complex protein 1
Neurospora
<M><P><M><Y><G><D><L><G><N><K><L><V><Q><H><A><K><R><T><Q><N><L><S><H><L><P><P><Y><Q><T><E><L><V><R><A><V><A><R><E><I><R><D><L><D><K><D><V><A><S><L><L><E><P><F><Q><G><S><F><D><P><S><A><E><Q><A><T><A><C><T><L><L><V><N><H><L><S><M><R><R><N><K><R><C><L><L><A><Y><H><R><I><R><T><D><K><L><E><E><L><V><W><N><G><A><D><I><L><D><L...
The GINS complex plays an essential role in the initiation of DNA replication.<BOP>
Q7SDH9
Q8PXV2
MFNB_METMA
4-(hydroxymethyl)-2-furancarboxaldehyde-phosphate synthase
Methanosarcina
<M><K><L><L><V><S><P><I><N><S><E><E><A><I><I><A><S><I><G><G><A><D><I><V><D><V><K><N><P><K><E><G><S><L><G><A><N><F><P><W><V><I><R><E><V><K><A><V><V><N><G><R><Q><P><I><S><A><T><I><G><D><F><N><Y><K><P><G><T><A><A><L><A><A><L><G><A><A><V><A><G><A><D><Y><I><K><V><G><L><Y><D><I><Q><T><E><S><Q><A><L><E><L><L><T><K><I><T><R><A...
Catalyzes the formation of 4-(hydroxymethyl)-2-furancarboxaldehyde phosphate (4-HFC-P) from two molecules of glyceraldehyde-3-P (GA-3-P).<BOP>
Q8PXV2
P0DMM0
APOE_PHYMC
Apolipoprotein E
Physeter
<M><K><V><L><W><V><A><L><V><I><T><L><L><A><G><C><Q><A><E><E><V><K><P><A><P><E><P><E><V><Q><L><G><Q><E><W><P><G><W><Q><G><S><Q><P><W><E><Q><A><L><G><R><F><W><D><Y><L><R><W><V><Q><T><L><S><D><Q><V><Q><E><E><L><L><S><T><Q><V><I><Q><E><L><T><V><L><M><D><E><T><M><K><E><V><K><A><Y><R><E><E><L><E><E><Q><L><G><P><V><A><Q><E><T...
APOE is an apolipoprotein, a protein associating with lipid particles, that mainly functions in lipoprotein-mediated lipid transport between organs via the plasma and interstitial fluids. APOE is a core component of plasma lipoproteins and is involved in their production, conversion and clearance. Apoliproteins are amp...
P0DMM0
Q2W2L3
RPOA_MAGSA
Transcriptase subunit alpha
Magnetospirillum
<M><I><Q><K><N><W><Q><E><L><I><K><P><N><K><L><H><V><E><P><G><A><D><P><Q><R><T><A><I><V><V><A><E><P><L><E><R><G><F><G><M><T><L><G><N><S><L><R><R><V><L><L><S><S><L><Q><G><A><A><V><T><A><I><Q><I><D><G><V><L><H><E><F><S><S><I><P><G><V><R><E><D><V><T><D><I><I><L><N><I><K><T><L><G><L><R><M><H><G><E><G><P><K><R><M><H><L><R><A...
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.<BOP>
Q2W2L3
Q128P8
PNCB_POLSJ
Nicotinate phosphoribosyltransferase
unclassified Polaromonas
<M><I><I><T><S><L><L><D><T><D><L><Y><K><F><T><M><M><Q><V><V><L><H><Q><F><P><G><A><E><V><E><Y><R><F><K><C><R><N><A><G><A><P><G><I><G><K><L><A><P><Y><V><N><E><I><R><E><E><I><R><G><L><C><N><L><R><F><Q><D><A><E><L><A><Y><L><K><A><M><R><F><I><K><S><D><F><V><D><F><L><G><I><F><K><L><N><E><K><Y><V><S><V><T><A><L><P><S><G><E><I...
Catalyzes the synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP.<BOP>
Q128P8
B2IYE4
AROA_NOSP7
5-enolpyruvylshikimate-3-phosphate synthase
Nostoc
<M><D><T><I><E><I><P><A><L><N><R><P><V><D><A><T><V><E><I><P><G><S><K><S><L><T><N><R><A><L><L><V><A><A><L><A><Q><G><D><S><I><L><E><N><A><L><F><S><E><D><S><E><Y><F><A><K><C><L><E><Q><L><G><I><P><I><T><L><N><P><H><L><A><Q><I><Q><L><A><G><R><G><G><E><I><P><A><K><Q><A><D><L><F><V><G><L><S><G><T><T><A><R><F><I><S><A><L><V><A...
Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.<BOP>
B2IYE4
Q04J43
STKP_STRP2
Eukaryotic-type Ser/Thr protein kinase
Streptococcus
<M><I><Q><I><G><K><I><F><A><G><R><Y><R><I><V><K><Q><I><G><R><G><G><M><A><D><V><Y><L><A><K><D><L><I><L><D><G><E><E><V><A><V><K><V><L><R><T><N><Y><Q><T><D><P><I><A><V><A><R><F><Q><R><E><A><R><A><M><A><D><L><D><H><P><H><I><V><R><I><T><D><I><G><E><E><D><G><Q><Q><Y><L><A><M><E><Y><V><A><G><L><D><L><K><R><Y><I><K><E><H><Y><P...
Protein kinase involved in signal transduction pathways that regulate various cellular processes. Likely senses intracellular peptidoglycan subunits present in the cell division septa of actively growing cells; thus, intracellular unlinked peptidoglycan may serve as the signal molecules that trigger StkP phosphorylatio...
Q04J43
B5ZXG4
DCTA_RHILW
C4-dicarboxylate transport protein
Rhizobium
<M><I><A><A><P><F><D><A><V><A><D><S><T><G><K><K><P><F><Y><S><H><L><Y><V><Q><V><L><A><A><I><A><A><G><I><L><L><G><H><F><Y><P><E><L><G><A><Q><L><K><P><L><G><D><A><F><I><K><L><V><K><M><I><I><A><P><V><I><F><L><T><V><A><T><G><I><A><G><M><S><D><L><K><K><V><G><R><V><A><G><K><A><M><L><Y><F><L><T><F><S><T><L><A><L><V><I><G><M><V...
Responsible for the transport of dicarboxylates such as succinate, fumarate, and malate from the periplasm across the membrane.<BOP>
B5ZXG4
Q03125
NRG1_YEAST
Zinc finger protein MSS1
Saccharomyces
<M><F><Y><P><Y><N><Y><S><N><L><N><V><S><T><M><P><A><L><P><G><I><S><A><F><D><G><M><Q><D><E><E><N><V><E><I><S><P><E><R><K><Y><Q><T><L><L><P><V><L><T><N><S><H><V><V><E><N><E><L><K><H><K><L><N><K><T><A><F><D><F><R><Y><Q><T><K><S><E><N><G><S><E><K><W><E><P><K><Y><L><I><T><P><N><L><Q><T><R><S><V><S><F><D><N><S><S><V><Q><Y><N...
Transcriptional repressor involved in regulation of glucose repression. Binds to UAS-1 in the STA1 promoter.<BOP>
Q03125
Q9PE40
CLPX_XYLFA
ATP-dependent Clp protease ATP-binding subunit ClpX
Xylella
<M><S><E><D><R><P><S><R><S><G><D><G><N><K><I><L><Y><C><S><F><C><G><K><S><Q><R><E><V><R><K><L><I><A><G><P><S><V><F><I><C><D><E><C><V><E><L><C><N><D><I><I><R><E><E><L><E><E><K><S><Q><S><A><R><S><S><L><P><K><P><K><E><I><L><E><V><L><D><Q><Y><V><I><G><Q><Q><R><A><K><R><T><L><A><V><A><V><Y><N><H><Y><K><R><I><E><S><R><H><K><N...
ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.<BOP>
Q9PE40
Q0G9I9
CYB6_LIRTU
Cytochrome b6
Liriodendron
<M><S><K><V><Y><D><W><F><E><E><R><L><E><I><Q><A><I><A><D><D><I><T><S><K><Y><V><P><P><H><V><N><I><F><Y><C><L><G><G><I><T><L><T><C><F><L><V><Q><V><A><T><G><F><A><M><T><F><Y><Y><R><P><T><V><T><E><A><F><A><S><V><Q><Y><I><M><T><E><A><N><F><G><W><L><I><R><S><V><H><R><W><S><A><S><M><M><V><L><M><M><I><L><H><V><F><R><V><Y><L><T...
Component of the cytochrome b6-f complex, which mediates electron transfer between photosystem II (PSII) and photosystem I (PSI), cyclic electron flow around PSI, and state transitions.<BOP>
Q0G9I9
B4EC68
GUAA_BURCJ
Glutamine amidotransferase
Burkholderia cepacia complex
<M><H><D><K><I><L><I><L><D><F><G><S><Q><V><T><Q><L><I><A><R><R><V><R><E><A><H><V><Y><C><E><I><H><P><N><D><V><S><D><D><F><V><R><E><F><A><P><K><A><V><I><L><S><G><S><H><A><S><T><Y><E><D><H><Q><L><R><A><P><Q><A><V><W><D><L><G><V><P><V><L><G><I><C><Y><G><M><Q><T><M><A><V><Q><L><G><G><K><V><E><W><S><D><H><R><E><F><G><Y><A><E...
Catalyzes the synthesis of GMP from XMP.<BOP>
B4EC68
Q7V8D2
SYT_PROMM
Threonyl-tRNA synthetase
Prochlorococcus
<M><P><I><I><A><L><P><D><G><N><K><K><K><F><D><Q><P><V><T><I><M><E><V><A><E><S><L><G><P><G><L><A><K><A><A><I><A><G><R><V><N><G><V><L><L><D><T><C><I><P><I><E><K><D><S><E><V><N><I><I><T><A><K><D><Q><D><G><I><E><T><I><R><H><S><F><A><H><L><I><G><H><A><V><K><Q><L><Y><P><E><A><K><M><A><I><G><P><V><I><E><D><G><F><Y><Y><D><I><A...
Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction: L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr). Also edits incorrectly charged L-seryl-tRNA(Thr).<BOP>
Q7V8D2
Q65LS8
HPR_BACLD
Protease production regulatory protein Hpr
Bacillus
<M><N><R><A><E><E><P><Y><T><V><K><E><A><L><L><F><S><Q><R><M><A><Q><L><S><K><A><L><W><K><S><I><E><K><D><W><Q><Q><W><I><K><P><Y><D><L><N><I><N><E><H><H><I><L><W><I><A><Y><Q><L><N><G><A><S><I><S><E><I><A><K><F><G><V><M><H><V><S><T><A><F><N><F><S><K><K><L><E><E><R><G><Y><L><E><F><S><K><K><L><N><D><K><R><N><T><Y><I><Q><L><T...
Negative regulator of protease production and sporulation.<BOP>
Q65LS8
Q7U5C2
HEM3_PARMW
Pre-uroporphyrinogen synthase
Parasynechococcus marenigrum
<M><A><L><T><E><L><R><I><A><S><R><R><S><Q><L><A><M><V><Q><T><N><W><V><K><A><E><L><E><K><A><H><P><G><L><T><I><T><V><E><A><M><A><T><Q><G><D><K><I><L><D><V><A><L><A><K><I><G><D><K><G><L><F><T><K><E><L><E><A><Q><M><L><V><G><R><A><E><I><A><V><H><S><L><K><D><L><P><T><N><L><P><E><G><L><M><L><G><C><I><T><E><R><E><D><P><A><D><A...
Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.<BOP>
Q7U5C2
A3MYU1
SYT_ACTP2
Threonyl-tRNA synthetase
Actinobacillus
<M><P><I><I><T><L><P><D><G><S><Q><R><Q><F><D><N><P><V><S><V><M><E><V><A><Q><S><I><G><A><G><L><A><K><A><T><I><A><G><R><V><N><G><E><R><R><D><A><C><D><I><I><S><E><D><S><S><L><E><I><I><T><A><K><D><E><D><G><L><E><I><I><R><H><S><C><A><H><L><L><G><H><A><I><K><Q><L><F><P><N><V><K><M><A><I><G><P><T><I><D><N><G><F><Y><Y><D><V><D...
Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction: L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr). Also edits incorrectly charged L-seryl-tRNA(Thr).<BOP>
A3MYU1
A7GZK0
RL7_CAMC5
50S ribosomal protein L7/L12
Campylobacter
<M><A><I><T><K><E><D><V><L><E><F><I><S><N><L><S><V><L><E><L><S><E><L><V><K><E><F><E><E><K><F><G><V><S><A><A><P><V><M><V><A><G><G><A><V><A><G><G><A><A><E><A><A><E><E><K><T><E><F><N><L><V><L><V><D><S><G><D><K><K><I><N><V><I><K><V><V><R><A><L><T><G><L><G><L><K><E><A><K><D><A><V><E><G><T><P><S><V><L><K><E><G><I><S><K><D><E...
Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation.<BOP>
A7GZK0
Q4ZLU8
RPIA_PSEU2
Phosphoriboisomerase A
Pseudomonas syringae
<M><T><Q><D><Q><L><K><Q><A><V><A><Q><A><A><V><D><F><I><L><P><K><L><D><D><K><S><I><V><G><V><G><T><G><S><T><A><N><C><F><I><D><A><L><A><K><H><K><A><A><F><D><G><A><V><A><S><S><Q><A><T><A><A><R><L><K><A><H><G><I><P><V><Y><E><L><N><T><V><S><D><L><E><F><Y><V><D><G><A><D><E><S><D><E><H><L><N><L><I><K><G><G><G><A><A><L><T><R><E...
Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate.<BOP>
Q4ZLU8
Q08920
NCBP2_YEAST
NCBP 20 kDa subunit
Saccharomyces
<M><S><L><E><E><F><D><E><V><K><Y><D><H><S><T><K><R><L><D><T><P><S><R><Y><L><L><R><K><A><R><R><N><P><N><G><L><Q><E><L><R><E><S><M><K><S><S><T><I><Y><V><G><N><L><S><F><Y><T><S><E><E><Q><I><Y><E><L><F><S><K><C><G><T><I><K><R><I><I><M><G><L><D><R><F><K><F><T><P><C><G><F><C><F><I><I><Y><S><C><P><D><E><A><L><N><A><L><K><Y><L...
Component of the CBC complex, which binds co-transcriptionally to the cap of pre-mRNAs and is involved in maturation, export and degradation of nuclear mRNAs. The CBC complex is required for efficient pre-mRNA splicing through efficient commitment complex and spliceosome formation. Together with NPL3, the CBC complex i...
Q08920
Q8KA50
PT1_BUCAP
Phosphotransferase system, enzyme I
Buchnera
<M><I><S><G><I><L><A><S><P><G><I><A><F><G><N><V><L><L><L><K><K><E><E><I><V><I><N><R><Q><N><I><S><T><E><N><I><K><T><E><I><N><K><F><F><N><G><R><K><K><S><V><K><Q><L><T><E><I><K><I><A><T><G><E><K><F><G><K><K><K><E><G><I><F><E><G><H><I><M><L><L><E><D><E><E><L><E><K><E><I><I><N><L><I><T><E><K><K><I><S><A><A><E><A><T><K><F><I...
General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phos...
Q8KA50
Q0HS04
APAH_SHESR
Diadenosine tetraphosphatase
Shewanella
<M><A><H><Y><F><V><G><D><V><Q><G><C><F><A><E><L><K><R><L><L><A><E><V><D><F><N><P><S><R><D><E><L><W><A><V><G><D><L><V><A><R><G><P><D><S><L><A><T><L><R><Y><F><Q><S><L><G><D><A><G><K><T><V><L><G><N><H><D><L><H><L><L><A><L><H><G><K><L><K><R><D><K><P><S><D><N><L><A><P><L><L><N><A><P><D><I><A><S><L><I><D><W><L><R><Q><Q><P><L...
Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP.<BOP>
Q0HS04
A1W581
DER_ACISJ
GTP-binding protein EngA
unclassified Acidovorax
<M><K><P><V><I><A><L><V><G><R><P><N><V><G><K><S><T><L><F><N><R><L><T><K><S><R><D><A><I><V><A><D><F><A><G><L><T><R><D><R><H><Y><G><N><G><R><Q><G><K><H><E><Y><I><V><I><D><T><G><G><F><E><P><D><A><S><S><G><I><Y><R><E><M><A><R><Q><T><Q><Q><A><V><A><E><A><D><V><V><V><F><V><V><D><V><R><G><G><L><S><A><Q><D><H><D><I><A><N><Y><L...
GTPase that plays an essential role in the late steps of ribosome biogenesis.<BOP>
A1W581
Q0RDP7
RNH2_FRAAA
Ribonuclease HII
Frankia
<M><R><P><R><G><V><V><I><R><R><D><A><G><L><F><G><Y><E><R><A><L><V><R><C><G><L><G><P><V><A><G><V><D><E><A><G><R><G><A><C><A><G><P><L><V><V><A><A><V><V><L><G><P><D><G><R><R><R><L><S><P><R><L><A><D><S><K><L><L><T><E><Q><V><R><E><G><L><F><D><E><V><L><R><A><A><A><D><W><S><A><V><V><I><P><A><A><E><I><D><R><T><G><V><H><V><A><N...
Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.<BOP>
Q0RDP7
Q8RLX0
SOXA_CHLTI
Thiosulfate-oxidizing multienzyme system protein SoxA
Chlorobaculum
<M><K><K><T><I><Q><R><G><L><F><T><G><A><L><V><L><L><T><A><M><T><S><K><P><A><H><A><A><V><N><Y><Q><A><L><V><D><A><D><V><K><K><F><Q><G><Y><F><L><K><E><F><P><G><V><K><L><E><D><F><G><D><G><V><Y><A><L><D><E><D><S><R><K><Q><W><K><E><M><E><E><F><P><P><Y><E><L><D><V><E><A><G><K><A><L><F><N><K><P><F><A><N><G><K><S><L><G><S><C><F...
C-type monoheme cytochrome, which is part of the SoxAX cytochrome complex involved in sulfur oxidation. The SoxAX complex catalyzes the formation of a heterodisulfide bond between the conserved cysteine residue on a sulfur carrier SoxYZ complex subunit SoxY and thiosulfate or other inorganic sulfur substrates. This lea...
Q8RLX0
B0KSC5
ISPF_PSEPG
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Pseudomonas
<M><R><I><G><H><G><Y><D><V><H><R><F><C><D><G><D><F><I><T><L><G><G><V><R><I><P><H><K><Y><G><L><L><A><H><S><D><G><D><V><L><L><H><A><L><S><D><A><L><L><G><A><A><A><L><G><D><I><G><K><H><F><P><D><T><D><P><Q><F><K><G><A><D><S><R><A><L><L><R><H><V><V><G><I><V><R><A><K><G><W><K><V><G><N><V><D><A><T><I><V><A><Q><A><P><K><M><A><P...
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a correspond...
B0KSC5
Q7UFU6
QUEC_RHOBA
Queuosine biosynthesis protein QueC
Rhodopirellula
<M><E><R><R><L><V><N><S><T><S><Q><S><K><T><E><S><A><Q><Q><D><A><G><K><A><V><V><L><L><S><G><G><L><D><S><A><T><C><V><A><I><A><R><D><Q><G><F><E><V><H><A><I><S><F><R><Y><G><Q><R><H><D><G><E><L><D><R><A><A><K><Q><A><S><L><M><G><V><V><S><H><R><V><I><D><I><D><L><A><Q><L><G><G><S><A><L><V><D><S><S><I><A><V><P><K><S><D><H><V><D...
Catalyzes the ATP-dependent conversion of 7-carboxy-7-deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)).<BOP>
Q7UFU6
C1DKZ4
LFTR_AZOVD
Phenyalanyltransferase
Azotobacter
<M><L><T><C><L><Q><R><D><S><L><S><F><P><P><L><E><R><A><L><H><Q><P><N><G><L><L><A><V><G><G><D><L><S><A><E><R><L><I><Q><A><Y><R><H><G><C><F><P><W><Y><Q><A><G><Q><P><I><L><W><W><S><P><D><P><R><T><V><L><F><P><R><E><L><H><V><S><R><S><L><R><K><V><L><R><Q><E><R><F><Q><V><S><F><D><R><D><F><A><A><V><I><Q><A><C><A><G><P><R><D><Y...
Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine.<BOP>
C1DKZ4
B2ADA5
GH6D_PODAN
Probable exoglucanase GH6D
Podospora anserina
<M><R><A><V><Y><A><I><L><A><G><L><L><A><T><G><S><A><S><P><L><E><A><R><Q><S><G><N><P><F><V><G><R><S><L><F><V><N><P><K><Y><S><E><S><L><E><R><T><R><Q><A><F><L><S><R><G><D><Q><T><N><A><A><K><V><Q><Y><V><Q><N><K><V><G><T><F><V><W><I><S><N><I><F><L><L><R><D><I><D><D><A><I><R><N><A><R><A><A><Q><S><R><G><E><K><P><I><V><G><L><V...
Probable exoglucanase that may play an important function in biomass degradation by catalyzing the hydrolysis of cellulose.<BOP>
B2ADA5
A9AES0
MINC_BURM1
Probable septum site-determining protein MinC
Burkholderia cepacia complex
<M><S><L><K><K><S><P><F><F><E><L><R><S><G><S><V><D><T><L><L><F><T><V><K><T><T><D><L><D><A><L><R><A><E><L><V><K><R><F><E><A><T><P><E><F><F><A><D><D><V><V><A><I><D><V><R><R><L><A><D><G><E><R><V><A><L><A><D><I><R><Q><M><L><S><D><V><R><M><R><P><V><G><V><V><A><L><A><T><Q><G><W><A><T><E><A><G><L><P><L><L><E><A><R><D><R><R><A...
Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization.<BOP>
A9AES0
B2JA13
PSBH_NOSP7
Photosystem II reaction center protein H
Nostoc
<M><A><Q><R><T><R><L><G><D><I><L><K><P><L><N><S><E><Y><G><K><V><A><P><G><W><G><T><T><P><V><M><A><V><F><M><A><L><F><F><V><F><L><L><I><I><L><Q><L><Y><N><R><S><L><L><V><Q><D><V><L><V><D><W><R><S><L><G><R>
One of the components of the core complex of photosystem II (PSII), required for its stability and/or assembly. PSII is a light-driven water:plastoquinone oxidoreductase that uses light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation. It consists of a c...
B2JA13
B1JX26
UREG_BURCC
Urease accessory protein UreG
Burkholderia cepacia complex
<M><N><A><P><A><P><S><S><V><R><R><T><K><K><L><P><P><L><R><V><G><I><G><G><P><V><G><S><G><K><T><T><L><L><E><M><L><C><K><A><M><R><D><R><Y><D><L><V><A><I><T><N><D><I><Y><T><K><E><D><Q><R><L><L><T><V><A><G><A><L><P><E><E><R><I><M><G><V><E><T><G><G><C><P><H><T><A><I><R><E><D><A><S><I><N><L><E><A><V><D><R><M><L><A><R><F><P><D...
Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG.<BOP>
B1JX26
B4SJX6
MURC_STRM5
UDP-N-acetylmuramoyl-L-alanine synthetase
Stenotrophomonas maltophilia group
<M><I><R><R><L><H><D><T><N><D><L><V><R><A><F><P><R><V><H><F><V><G><I><G><G><T><G><M><S><G><I><A><E><V><M><L><T><L><G><Y><E><V><S><G><S><D><N><A><D><N><V><A><T><R><R><L><A><S><L><G><A><R><I><M><R><G><H><S><A><A><N><V><L><G><T><D><C><V><V><V><S><S><A><I><R><E><D><N><P><E><L><M><E><A><R><S><Q><R><I><P><I><M><P><R><A><A><M...
Cell wall formation.<BOP>
B4SJX6
Q8DD43
TRMA_VIBVU
tmRNA (uracil(341)-C(5))-methyltransferase
Vibrio
<M><A><T><L><D><V><N><P><Q><R><Y><Q><Q><Q><L><A><E><K><V><Q><R><L><T><D><M><F><A><P><Y><Q><A><P><E><L><E><V><F><E><S><P><D><Q><H><Y><R><M><R><A><E><F><R><V><W><H><E><G><E><E><M><Y><Y><I><M><F><N><Q><E><T><R><E><K><Y><R><V><D><Q><F><P><A><A><S><R><L><I><N><D><L><M><P><L><L><I><D><A><M><K><D><N><E><S><L><R><R><K><L><F><Q...
Dual-specificity methyltransferase that catalyzes the formation of 5-methyluridine at position 54 (m5U54) in all tRNAs, and that of position 341 (m5U341) in tmRNA (transfer-mRNA).<BOP>
Q8DD43
A7Z4C5
COAD_BACVZ
Pantetheine-phosphate adenylyltransferase
Bacillus amyloliquefaciens group
<M><A><S><I><A><V><C><P><G><S><F><D><P><V><T><Y><G><H><L><D><I><I><R><R><G><A><N><V><F><E><Q><V><Y><V><C><V><L><N><N><S><S><K><Q><P><L><F><T><V><E><E><R><C><E><L><L><R><E><V><T><K><D><I><P><N><V><T><V><E><T><S><Q><G><L><L><I><D><Y><A><K><K><K><R><A><K><A><I><I><R><G><L><R><A><V><S><D><F><E><Y><E><M><Q><G><T><S><V><N><R...
Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.<BOP>
A7Z4C5
Q47BG9
AMPA_DECAR
Leucyl aminopeptidase
Dechloromonas
<M><E><F><S><I><K><S><G><S><P><E><K><Q><R><S><A><C><V><V><V><G><V><F><E><S><R><K><M><T><L><P><A><E><L><L><D><K><A><S><G><G><Y><I><S><D><I><V><R><R><G><D><M><E><G><K><A><G><S><T><L><L><L><H><S><V><P><S><T><L><C><D><R><I><L><L><V><G><L><G><K><E><K><D><F><R><E><K><E><F><A><S><A><I><R><T><A><V><K><V><L><N><E><T><G><A><F><D...
Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides.<BOP>
Q47BG9
O18728
FSCN2_BOVIN
Retinal fascin
Bos
<M><P><T><N><G><L><H><Q><V><L><K><I><Q><F><G><L><V><N><D><T><D><R><Y><L><T><A><E><S><F><G><F><K><V><N><A><S><A><P><S><L><K><R><K><Q><M><W><V><L><E><P><D><P><G><E><G><T><A><V><L><F><R><S><S><H><L><G><R><Y><L><S><A><E><E><D><G><R><V><A><C><E><A><E><R><P><G><R><D><C><R><F><L><V><L><P><Q><P><D><G><R><W><V><L><Q><S><E><P><H...
Acts as an actin bundling protein. May play a pivotal role in photoreceptor cell-specific events, such as disk morphogenesis.<BOP>
O18728
P0CW43
FWDC_METMP
Tungsten-containing formylmethanofuran dehydrogenase II subunit C
Methanococcus
<M><N><E><L><I><L><N><L><K><G><D><V><S><V><P><V><E><M><D><K><I><L><P><E><K><I><Q><E><M><S><L><E><E><I><S><G><I><E><L><I><Q><G><N><K><T><A><K><V><S><E><I><F><D><V><E><L><K><E><S><D><V><A><K><V><T><I><N><N><C><C><K><K><V><K><R><I><G><E><K><M><T><S><G><E><I><V><V><N><G><D><A><G><M><Y><I><G><V><E><M><K><G><G><K><I><T><V><N...
Catalyzes the reversible oxidation of CO(2) and methanofuran (MFR) to N-formylmethanofuran (CHO-MFR). This enzyme is oxygen-labile.<BOP>
P0CW43
C5BB97
HLDD_EDWI9
ADP-L-glycero-beta-D-manno-heptose-6-epimerase
Edwardsiella
<M><I><I><V><T><G><G><A><G><M><I><G><S><N><I><V><K><A><L><N><D><K><G><Y><T><D><I><L><V><V><D><N><L><K><D><G><T><K><F><V><N><L><V><D><L><D><I><T><D><Y><M><D><K><E><D><F><I><A><G><I><V><A><G><D><D><F><G><D><I><D><A><V><F><H><E><G><A><C><S><S><T><T><E><W><D><G><K><Y><V><M><D><N><N><Y><Q><Y><S><K><E><L><L><H><F><C><L><E><R...
Catalyzes the interconversion between ADP-D-glycero-beta-D-manno-heptose and ADP-L-glycero-beta-D-manno-heptose via an epimerization at carbon 6 of the heptose.<BOP>
C5BB97
C5B7R2
LEUC_EDWI9
Isopropylmalate isomerase
Edwardsiella
<M><G><K><T><L><Y><Q><K><L><Y><D><A><H><I><V><H><Q><T><P><G><E><T><P><L><L><Y><I><D><R><H><L><V><H><E><V><T><S><P><Q><A><F><D><G><L><R><A><Q><R><R><R><V><R><R><P><E><H><T><F><A><T><M><D><H><N><V><S><T><Q><S><R><D><I><H><A><C><G><E><M><A><R><V><Q><M><E><T><L><M><A><N><C><R><E><F><G><V><Q><L><Y><D><L><H><H><P><H><Q><G><I...
Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.<BOP>
C5B7R2
C0RFV3
DCUP_BRUMB
Uroporphyrinogen decarboxylase
Brucella
<M><N><L><K><V><L><K><V><I><D><G><E><T><V><F><P><P><P><I><W><M><M><R><Q><A><G><R><Y><L><P><E><Y><R><E><T><R><K><K><A><G><S><F><L><D><L><C><Y><S><P><D><L><A><V><E><V><T><L><Q><P><I><R><R><F><G><F><D><A><A><I><L><F><S><D><I><L><V><V><P><H><A><L><G><R><D><L><R><F><E><E><G><K><G><P><L><M><T><P><I><D><A><D><E><I><F><W><L><E...
Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.<BOP>
C0RFV3
Q0STR1
HFQ_CLOPS
RNA-binding protein Hfq
Clostridium
<M><N><K><S><I><N><N><L><Q><D><I><F><L><N><N><A><R><K><E><R><I><P><V><T><I><F><L><V><N><G><V><Q><L><K><G><I><V><K><G><F><D><S><F><T><V><V><L><D><S><D><G><K><Q><Q><L><V><Y><K><H><A><I><S><T><V><S><P><A><K><P><I><L><F><N><S><A><Q><V><F><D><N>
RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs.<BOP>
Q0STR1
P33376
PHLD_BACCE
Phosphatidylcholine cholinephosphohydrolase
Bacillus cereus group
<M><K><K><K><V><L><A><L><G><A><A><I><T><L><V><A><P><L><Q><S><V><A><F><A><H><E><N><D><G><G><Q><R><F><G><V><I><P><R><W><S><A><E><D><K><H><K><E><G><V><N><S><H><L><W><I><V><N><R><A><I><D><I><M><S><R><N><T><T><L><V><K><Q><D><R><V><A><L><L><N><E><W><R><T><E><L><E><N><G><I><Y><A><A><D><Y><E><N><P><Y><Y><D><N><S><T><F><A><S><H...
Required, with sphingomyelinase, to effect target cell lysis (hemolysis).<BOP>
P33376
B1LM67
BIOF_ECOSM
8-amino-7-ketopelargonate synthase
Escherichia
<M><S><W><Q><E><K><I><N><A><A><L><D><A><R><R><A><A><D><A><L><R><R><R><Y><P><V><A><Q><G><A><G><R><W><L><V><A><D><D><R><H><Y><L><N><F><S><S><N><D><Y><L><G><L><S><H><H><P><Q><I><I><R><A><W><K><L><S><A><E><Q><F><G><V><G><S><G><G><S><G><H><V><S><G><Y><S><V><A><H><Q><A><L><E><E><E><L><A><E><W><L><G><Y><S><R><A><L><L><F><I><S...
Catalyzes the decarboxylative condensation of pimeloyl-[acyl-carrier protein] and L-alanine to produce 8-amino-7-oxononanoate (AON), [acyl-carrier protein], and carbon dioxide.<BOP>
B1LM67
A4XYC6
G6PI_PSEMY
Phosphohexose isomerase
Pseudomonas
<M><A><Y><Y><Q><Q><P><H><D><I><T><R><L><P><A><W><Q><A><L><Q><Q><H><R><A><E><M><A><G><F><S><M><R><E><A><F><A><G><D><P><R><R><F><Q><R><F><S><L><D><S><C><G><L><L><L><D><Y><S><K><N><L><I><T><E><K><S><L><E><L><L><I><Q><L><A><E><Q><A><D><L><H><E><A><I><A><A><L><Y><N><G><E><R><V><N><A><S><E><G><R><A><A><L><H><T><A><L><R><S><P...
Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.<BOP>
A4XYC6
B9LMX0
AROC_HALLT
5-enolpyruvylshikimate-3-phosphate phospholyase
Halorubrum
<M><N><G><N><R><F><G><R><L><F><Q><V><T><T><Y><G><E><S><H><G><E><A><M><G><V><T><V><S><G><V><P><A><G><V><E><L><D><E><E><A><I><Q><A><Q><L><D><R><R><K><P><G><Q><S><M><I><T><T><S><R><G><E><P><D><E><V><V><V><N><S><G><V><Q><D><G><Y><T><T><G><T><P><I><G><M><V><I><Q><N><K><D><A><R><S><G><K><Y><E><P><Y><V><T><A><P><R><P><S><H><G...
Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a s...
B9LMX0
Q4UTA3
RS6_XANC8
30S ribosomal protein S6
Xanthomonas
<M><S><R><H><Y><E><V><V><F><L><V><H><P><D><Q><S><E><Q><V><P><A><M><I><E><R><Y><K><S><L><I><E><G><G><N><G><T><I><H><R><L><E><D><W><G><R><R><Q><L><A><Y><P><I><Q><N><L><V><K><A><H><Y><V><L><L><N><I><E><V><D><Q><A><V><L><S><E><L><V><E><S><F><R><F><N><D><A><V><L><R><H><L><V><I><K><R><D><G><P><D><T><E><Q><S><L><I><M><K><S><K...
Binds together with S18 to 16S ribosomal RNA.<BOP>
Q4UTA3
Q5VH50
MATK_BATMA
Intron maturase
Batis
<M><E><E><F><Q><V><Y><L><E><L><H><K><A><H><N><F><L><Y><P><L><F><F><Q><E><Y><I><Y><A><L><A><H><N><H><R><L><N><R><L><N><R><S><S><L><F><Q><N><G><D><Y><D><N><K><F><S><S><L><I><V><K><R><L><I><F><R><M><Y><Q><Q><N><N><F><I><I><S><T><K><N><L><N><Q><N><T><F><F><S><H><N><K><N><L><Y><Y><Q><I><I><S><V><V><L><A><V><I><V><E><I><P><F...
Usually encoded in the trnK tRNA gene intron. Probably assists in splicing its own and other chloroplast group II introns.<BOP>
Q5VH50
Q16629
SRSF7_HUMAN
Splicing factor, arginine/serine-rich 7
Homo
<M><S><R><Y><G><R><Y><G><G><E><T><K><V><Y><V><G><N><L><G><T><G><A><G><K><G><E><L><E><R><A><F><S><Y><Y><G><P><L><R><T><V><W><I><A><R><N><P><P><G><F><A><F><V><E><F><E><D><P><R><D><A><E><D><A><V><R><G><L><D><G><K><V><I><C><G><S><R><V><R><V><E><L><S><T><G><M><P><R><R><S><R><F><D><R><P><P><A><R><R><P><F><D><P><N><D><R><C><Y...
Required for pre-mRNA splicing. Can also modulate alternative splicing in vitro. Represses the splicing of MAPT/Tau exon 10. May function as export adapter involved in mRNA nuclear export such as of histone H2A. Binds mRNA which is thought to be transferred to the NXF1-NXT1 heterodimer for export (TAP/NXF1 pathway); en...
Q16629
B0R611
CBIM_HALS3
Energy-coupling factor transporter probable substrate-capture protein CbiM
Halobacterium
<M><H><I><M><E><G><F><L><P><G><I><W><A><L><V><W><F><V><V><A><I><P><V><I><S><Y><G><A><L><K><T><A><R><L><A><R><N><D><E><L><N><K><S><H><I><A><V><A><A><A><F><I><F><V><L><S><A><L><K><I><P><S><V><T><G><S><T><S><H><P><T><G><T><G><I><A><V><V><L><F><G><P><A><V><T><A><F><L><S><A><I><V><L><L><Y><Q><A><L><L><L><G><H><G><G><L><T><T...
Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import.<BOP>
B0R611
C6BUK3
DAPAT_MARSD
LL-diaminopimelate aminotransferase
Maridesulfovibrio
<M><P><E><F><K><L><A><D><R><L><A><T><L><P><P><Y><L><F><A><E><I><D><R><L><K><A><E><V><A><A><Q><G><V><D><I><I><S><L><G><I><G><D><P><D><L><P><T><P><D><F><I><I><E><A><L><H><K><A><A><K><N><P><V><N><H><Q><Y><P><S><Y><V><G><L><L><T><F><R><Q><A><V><A><D><W><Y><K><E><R><F><D><V><E><L><D><A><T><K><E><V><V><S><L><I><G><S><K><E><G...
Involved in the synthesis of meso-diaminopimelate (m-DAP or DL-DAP), required for both lysine and peptidoglycan biosynthesis. Catalyzes the direct conversion of tetrahydrodipicolinate to LL-diaminopimelate.<BOP>
C6BUK3
A4QWP8
MEP_MAGO7
Fungalysin MEP
Pyricularia
<M><R><Y><S><L><S><L><A><L><L><G><V><A><A><V><T><V><V><A><H><P><H><T><P><G><R><H><G><V><E><R><R><A><I><D><L><D><A><F><R><L><Q><P><T><A><E><Y><V><P><K><E><E><V><P><D><Q><S><S><L><A><F><I><S><N><D><N><Y><V><D><V><A><T><D><L><V><K><S><V><A><P><G><I><E><F><R><V><V><G><D><H><Y><V><G><T><N><G><V><A><H><V><N><F><K><Q><T><A><H...
Secreted metalloproteinase that allows assimilation of proteinaceous substrates.<BOP>
A4QWP8
Q6NWG0
TSN36_DANRE
Tetraspanin-3c
Danio
<M><D><C><G><I><I><T><S><K><T><I><L><L><L><L><S><L><I><F><W><A><A><G><A><A><L><A><Y><V><G><S><Y><V><I><K><S><Y><N><N><F><E><D><F><M><S><D><R><H><T><L><I><P><A><A><I><I><I><G><V><A><V><V><M><F><I><I><G><F><V><G><C><C><A><T><L><R><E><S><K><V><G><L><G><L><F><L><I><I><I><M><L><I><F><A><A><E><V><T><A><F><V><F><G><I><I><Y><R...
Plays a role in migration and segregation of pigment cells (melanophores and xanthophores). Contributes to pigment stripe patterning in the epidermis.<BOP>
Q6NWG0
O14640
DVL1_HUMAN
DSH homolog 1
Homo
<M><A><E><T><K><I><I><Y><H><M><D><E><E><E><T><P><Y><L><V><K><L><P><V><A><P><E><R><V><T><L><A><D><F><K><N><V><L><S><N><R><P><V><H><A><Y><K><F><F><F><K><S><M><D><Q><D><F><G><V><V><K><E><E><I><F><D><D><N><A><K><L><P><C><F><N><G><R><V><V><S><W><L><V><L><A><E><G><A><H><S><D><A><G><S><Q><G><T><D><S><H><T><D><L><P><P><P><L><E...
Participates in Wnt signaling by binding to the cytoplasmic C-terminus of frizzled family members and transducing the Wnt signal to down-stream effectors. Plays a role both in canonical and non-canonical Wnt signaling. Plays a role in the signal transduction pathways mediated by multiple Wnt genes. Required for LEF1 ac...
O14640
C3N0D7
CAPPA_SULIA
Phosphoenolpyruvate carboxylase
Sulfolobus
<M><R><I><I><P><R><T><M><S><T><Q><H><P><D><N><A><K><V><P><E><W><A><K><S><E><V><I><E><G><E><D><E><V><K><E><A><F><L><A><Y><S><M><Y><G><V><H><E><V><M><W><D><A><E><G><K><D><V><D><T><H><V><V><R><K><L><L><S><N><Y><P><D><Y><F><R><E><H><I><L><G><K><D><V><F><L><T><Y><R><L><P><N><P><K><V><E><G><A><D><R><K><V><F><A><E><T><M><E><S...
Catalyzes the irreversible beta-carboxylation of phosphoenolpyruvate (PEP) to form oxaloacetate (OAA), a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle.<BOP>
C3N0D7
Q47758
DDL_ENTFA
D-alanylalanine synthetase
Enterococcus
<M><K><I><I><L><L><Y><G><G><R><S><E><E><H><D><V><S><V><L><S><A><Y><S><V><L><N><A><I><Y><Y><K><Y><Y><Q><V><Q><L><V><F><I><S><K><D><G><Q><W><V><K><G><P><L><L><S><E><R><P><Q><N><K><E><V><L><H><L><T><W><A><Q><T><P><E><E><T><G><E><F><S><G><K><R><I><S><P><S><E><I><Y><E><E><E><A><I><V><F><P><V><L><H><G><P><N><G><E><D><G><T><I...
Cell wall formation.<BOP>
Q47758
Q58DT1
RL7_BOVIN
60S ribosomal protein L7
Bos
<M><E><G><A><E><E><K><K><K><K><V><P><A><V><P><E><T><L><K><K><K><R><K><N><F><A><E><L><K><I><K><R><L><R><K><K><F><A><Q><K><M><L><R><K><A><R><R><K><L><I><Y><E><K><A><K><H><Y><H><K><E><Y><R><Q><M><Y><R><T><E><I><R><M><A><R><M><A><R><K><A><G><N><F><Y><V><P><A><E><P><K><L><A><F><V><I><R><I><R><G><I><N><G><V><S><P><K><V><R><K...
Component of the large ribosomal subunit. The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell. Binds to G-rich structures in 28S rRNA and in mRNAs. Plays a regulatory role in the translation apparatus; inhibits cell-free translation of mRNAs.<BOP>
Q58DT1
P32879
3S11_AIPLA
Short neurotoxin A
Aipysurus
<L><T><C><C><N><Q><Q><S><S><Q><P><K><T><T><T><D><C><A><D><N><S><C><Y><K><K><T><W><Q><D><H><R><G><T><R><I><E><R><G><C><G><C><P><Q><V><K><P><G><I><K><L><E><C><C><K><T><N><E><C><N><N>
Binds to muscle nicotinic acetylcholine receptor (nAChR) and inhibit acetylcholine from binding to the receptor, thereby impairing neuromuscular transmission.<BOP>
P32879
Q8A483
RL16_BACTN
50S ribosomal protein L16
Bacteroides
<M><L><Q><P><K><K><T><K><F><R><R><Q><Q><K><G><R><A><K><G><N><A><Q><R><G><N><Q><L><A><F><G><S><F><G><I><K><A><L><E><T><K><W><I><T><G><R><Q><I><E><A><A><R><I><A><V><T><R><Y><M><Q><R><Q><G><Q><I><W><I><R><I><F><P><D><K><P><I><T><R><K><P><A><D><V><R><M><G><K><G><K><G><A><P><E><G><F><V><A><P><V><T><P><G><R><I><I><I><E><A><E...
Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.<BOP>
Q8A483
B7HHH6
CYSH_BACC4
Thioredoxin-dependent 5'-adenylylsulfate reductase
Bacillus cereus group
<M><L><T><Y><E><T><W><E><E><N><V><V><S><F><S><E><E><D><E><T><K><G><A><L><S><V><L><N><W><A><Y><K><E><Y><K><D><E><V><V><Y><A><C><S><F><G><V><E><G><M><V><L><L><H><I><I><N><Q><V><N><P><S><A><K><V><V><F><L><D><T><N><V><H><F><Q><E><T><Y><E><L><I><Q><K><V><R><E><R><F><P><S><L><N><I><I><E><K><Q><P><E><L><T><L><D><E><Q><A><K><L...
Catalyzes the formation of sulfite from adenosine 5'-phosphosulfate (APS) using thioredoxin as an electron donor.<BOP>
B7HHH6
P06389
RK22_TOBAC
50S ribosomal protein L22, chloroplastic
Nicotiana
<M><L><K><K><K><K><T><E><V><Y><A><L><G><E><H><I><S><M><S><A><D><K><A><R><R><V><I><N><Q><I><R><G><R><S><Y><E><E><T><L><M><I><L><E><L><M><P><Y><R><A><C><Y><P><I><L><K><L><I><Y><S><A><A><A><N><A><S><Y><N><M><G><S><S><E><A><N><L><V><I><S><K><A><E><V><N><G><G><T><T><V><K><K><L><K><P><R><A><R><G><R><S><F><P><I><K><R><S><T><C...
The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.<BOP>
P06389
Q0I7X4
CY550_SYNS3
Low-potential cytochrome c
unclassified Synechococcus
<M><A><S><F><F><S><T><L><R><R><S><L><N><R><L><L><I><A><L><P><V><L><L><G><L><M><I><S><T><P><A><Q><A><A><Q><W><D><A><E><T><L><T><V><P><A><D><G><D><G><A><L><V><T><F><S><E><Q><E><I><K><T><G><R><K><V><F><N><V><S><C><G><T><C><H><A><G><G><I><T><K><T><N><Q><N><V><G><L><D><T><E><T><L><A><L><A><T><P><A><R><D><N><V><A><S><L><V><D...
Low-potential cytochrome c that plays a role in the oxygen-evolving complex of photosystem II.<BOP>
Q0I7X4
Q5L411
RL5_GEOKA
50S ribosomal protein L5
Geobacillus thermoleovorans group
<M><N><R><L><K><E><K><Y><L><N><E><V><V><P><A><L><M><S><K><F><N><Y><K><S><I><M><Q><V><P><K><I><E><K><I><V><I><N><M><G><V><G><D><A><V><Q><N><P><K><A><L><D><S><A><V><E><E><L><T><L><I><A><G><Q><R><P><V><V><T><R><A><K><K><S><I><A><G><F><R><L><R><Q><G><M><P><I><G><A><K><V><T><L><R><G><E><R><M><Y><E><F><L><D><K><L><I><S><V><S...
This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement...
Q5L411
Q8CTZ3
BIOW_STAES
Pimeloyl-CoA synthase
Staphylococcus
<M><Y><S><I><K><M><R><A><S><H><E><D><I><H><I><S><G><A><E><T><M><C><E><F><E><D><L><E><N><Y><L><K><K><Y><F><N><K><A><F><N><H><E><N><G><N><I><D><F><L><N><L><K><I><E><K><V><K><A><P><I><Q><T><L><V><A><L><P><V><V><E><N><L><N><D><T><L><T><Q><L><A><K><Q><T><G><V><S><E><Y><A><L><N><K><G><L><E><F><I><K><N><D><I><T><Y><T><G><A><I...
Catalyzes the transformation of pimelate into pimeloyl-CoA with concomitant hydrolysis of ATP to AMP.<BOP>
Q8CTZ3
Q14296
FASTK_HUMAN
Fas-activated serine/threonine kinase
Homo
<M><R><R><P><R><G><E><P><G><P><R><A><P><R><P><T><E><G><A><T><C><A><G><P><G><E><S><W><S><P><S><P><N><S><M><L><R><V><L><L><S><A><Q><T><S><P><A><R><L><S><G><L><L><L><I><P><P><V><Q><P><C><C><L><G><P><S><K><W><G><D><R><P><V><G><G><G><P><S><A><G><P><V><Q><G><L><Q><R><L><L><E><Q><A><K><S><P><G><E><L><L><R><W><L><G><Q><N><P><S...
Required for the biogenesis of some mitochondrial-encoded mRNAs, specifically stabilizes ND6 (NADH dehydrogenase complex subunit 6) mRNA, and regulates its levels.<BOP>
Q14296
Q9QXW0
FBXL6_MOUSE
F-box protein FBL6
Mus
<M><A><P><V><A><S><R><R><V><R><R><R><V><R><S><S><K><R><P><D><A><R><G><R><S><A><E><D><W><W><W><D><R><L><A><P><R><G><S><G><Y><H><L><L><Q><A><D><S><M><L><L><V><L><P><D><L><E><P><P><R><A><R><A><H><R><R><A><R><R><R><A><P><R><S><L><A><R><G><P><T><A><V><A><K><P><R><T><K><P><R><P><E><P><S><L><D><Q><G><L><D><S><G><W><G><D><R><I...
Substrate-recognition component of the SCF (SKP1-CUL1-F-box protein)-type E3 ubiquitin ligase complex.<BOP>
Q9QXW0
Q3SK28
IHFA_THIDA
Integration host factor subunit alpha
Thiobacillus
<M><T><T><L><T><K><A><D><L><A><E><L><L><F><E><K><V><G><L><N><K><R><E><A><K><D><V><V><E><S><F><F><D><E><I><R><L><A><L><E><K><G><D><I><V><K><L><S><G><F><G><N><F><Q><C><R><E><K><P><Q><R><P><G><R><N><P><K><T><G><E><E><M><P><I><S><A><R><R><V><V><T><F><H><A><S><Q><K><L><K><S><Q><V><E><G><A><R><I><G><T><P><S><Q><E>
This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control.<BOP>
Q3SK28
Q9WVC6
SGK1_MOUSE
Serum/glucocorticoid-regulated kinase 1
Mus
<M><T><V><K><A><E><A><A><R><S><T><L><T><Y><S><R><M><R><G><M><V><A><I><L><I><A><F><M><K><Q><R><R><M><G><L><N><D><F><I><Q><K><I><A><S><N><T><Y><A><C><K><H><A><E><V><Q><S><I><L><K><M><S><H><P><Q><E><P><E><L><M><N><A><N><P><S><P><P><P><S><P><S><Q><Q><I><N><L><G><P><S><S><N><P><H><A><K><P><S><D><F><H><F><L><K><V><I><G><K><G...
Serine/threonine-protein kinase which is involved in the regulation of a wide variety of ion channels, membrane transporters, cellular enzymes, transcription factors, neuronal excitability, cell growth, proliferation, survival, migration and apoptosis. Plays an important role in cellular stress response. Contributes to...
Q9WVC6
P23620
PHOB_PSEAE
Phosphate regulon transcriptional regulatory protein PhoB
Pseudomonas
<M><V><G><K><T><I><L><I><V><D><D><E><A><P><I><R><E><M><I><A><V><A><L><E><M><A><G><Y><E><C><L><E><A><E><N><T><Q><Q><A><H><A><V><I><V><D><R><K><P><D><L><I><L><L><D><W><M><L><P><G><T><S><G><I><E><L><A><R><R><L><K><R><D><E><L><T><V><D><I><P><I><I><M><L><T><A><K><G><E><E><D><N><K><I><Q><G><L><E><V><G><A><D><D><Y><I><T><K><P...
This protein is a positive regulator for the phosphate regulon. Transcription of this operon is positively regulated by PhoB and PhoR when phosphate is limited.<BOP>
P23620
Q8EHD3
UPPP1_SHEON
Undecaprenyl pyrophosphate phosphatase 1
Shewanella
<M><D><T><F><Q><V><I><I><L><A><L><I><Q><G><L><T><E><F><L><P><I><S><S><S><A><H><L><I><L><P><A><Q><L><L><G><W><E><D><Q><G><L><S><F><D><V><A><V><N><T><G><S><L><F><A><V><V><I><Y><F><R><H><E><L><W><A><M><F><K><A><W><I><A><S><I><V><K><G><Q><H><S><D><D><S><K><L><A><W><W><I><I><L><A><T><L><P><A><V><F><F><G><F><M><A><K><D><F><I...
Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin.<BOP>
Q8EHD3
O33406
MBHL_AFIC5
Membrane-bound hydrogenase large subunit
Afipia
<M><S><V><I><Q><T><P><N><G><Y><K><L><D><N><S><G><R><R><V><V><V><D><P><V><T><R><I><E><G><H><M><R><C><E><V><N><V><D><S><N><N><V><I><R><N><A><V><S><T><G><T><M><W><R><G><L><E><V><I><L><K><G><R><D><P><R><D><A><W><A><F><V><E><R><I><C><G><V><C><T><G><C><H><A><L><A><S><V><R><A><V><E><N><A><L><D><I><R><I><P><P><N><A><H><L><I><R...
This enzyme recycles the H(2) produced by nitrogenase to increase the production of ATP and to protect nitrogenase against inhibition or damage by O(2) under carbon- or phosphate-limited conditions.<BOP>
O33406
Q8D3J7
ATPF_WIGBR
F-type ATPase subunit b
Wigglesworthia
<M><N><I><N><A><T><I><F><G><Q><T><I><A><F><F><L><F><V><F><F><C><M><K><Y><I><W><P><N><L><I><S><L><V><E><K><R><R><E><N><I><A><Q><A><L><N><E><A><K><Q><A><K><L><N><L><K><I><S><K><E><K><A><K><K><R><I><E><S><A><Q><I><K><C><K><N><I><I><N><E><A><N><E><T><K><K><L><L><I><E><E><A><K><K><E><A><I><K><I><K><E><H><I><I><S><Q><G><R><L...
Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0).<BOP>
Q8D3J7
Q61249
IGBP1_MOUSE
p52
Mus
<M><A><A><S><E><D><E><L><L><L><P><R><L><P><E><L><F><E><T><S><K><K><L><L><E><D><V><E><V><A><T><E><P><T><G><S><R><T><I><Q><D><K><V><S><K><G><L><E><L><L><E><K><A><A><G><M><L><S><Q><L><D><L><F><S><R><N><E><D><L><E><E><I><A><S><T><D><L><K><Y><L><M><V><P><A><L><Q><G><A><L><T><M><K><Q><V><N><P><S><K><R><L><D><H><L><Q><R><A><R...
Associated to surface IgM-receptor; may be involved in signal transduction. Involved in regulation of the catalytic activity of the phosphatases PP2A, PP4 and PP6 by protecting their partially folded catalytic subunits from degradative polyubiquitination until they associate with regulatory subunits.<BOP>
Q61249