accession stringlengths 6 10 | name stringlengths 6 11 | Full Name stringlengths 1 147 ⌀ | taxon stringlengths 3 46 ⌀ | sequence stringlengths 48 2.3k | function stringlengths 11 1.34k | AlphaFoldDB stringlengths 6 10 |
|---|---|---|---|---|---|---|
Q64689 | SIA8C_MOUSE | Sialyltransferase St8Sia III | Mus | <M><R><N><C><K><M><A><R><V><A><S><V><L><G><L><V><M><L><S><V><A><L><L><I><L><S><L><I><S><Y><V><S><L><K><K><E><N><I><F><T><T><P><K><Y><A><S><P><G><A><P><R><M><Y><M><F><H><A><G><F><R><S><Q><F><A><L><K><F><L><D><Q><S><F><V><P><I><T><N><S><L><T><H><E><L><Q><E><K><P><S><K><W><T><F><N><R><T><A><F><L><H><Q><R><Q><E><I><L><Q><H... | Catalyzes the transfer of sialic acid from a CMP-linked sialic acid donor onto the terminal sialic acid of an acceptor through alpha-2,8-linkages. Is active with alpha-2,3-linked, alpha-2,6-linked and alpha-2,8-linked sialic acid of N-linked oligosaccharides of glycoproteins and glycolipids. Displays preference for sub... | Q64689 |
P70691 | UD12_MOUSE | UDP-glucuronosyltransferase 1A2 | Mus | <M><D><T><G><L><C><V><P><L><R><G><I><S><G><L><L><L><L><L><C><A><L><P><W><A><E><G><A><K><V><L><V><L><P><M><E><G><S><Q><W><L><S><M><R><D><V><V><R><E><L><H><A><R><G><H><Q><T><V><V><L><A><S><E><V><T><V><H><I><K><G><E><D><F><F><T><L><K><T><Y><A><F><P><Y><T><K><E><E><Y><Q><Q><E><I><L><S><D><I><E><K><T><F><K><T><Q><H><F><V><K... | UDPGT is of major importance in the conjugation and subsequent elimination of potentially toxic xenobiotics and endogenous compounds.<BOP> | P70691 |
Q9XZK4 | O165_CONST | Omega-conotoxin-like SO-5 | Pionoconus | <M><K><L><T><C><V><M><I><V><A><V><L><L><L><T><A><C><Q><L><I><T><A><D><D><S><R><G><T><Q><K><H><R><S><L><R><S><T><T><K><V><S><K><S><T><S><C><M><E><A><G><S><Y><C><G><S><T><T><R><I><C><C><G><Y><C><A><Y><F><G><K><K><C><I><D><Y><P><S><N> | Omega-conotoxins act at presynaptic membranes, they bind and block voltage-gated calcium channels (Cav).<BOP> | Q9XZK4 |
A4XQ00 | RL9_PSEMY | 50S ribosomal protein L9 | Pseudomonas | <M><E><V><I><L><L><E><K><I><A><N><L><G><N><L><G><D><K><V><N><V><K><A><G><Y><G><R><N><F><L><L><P><Q><G><K><A><T><A><A><T><A><E><N><V><A><A><F><E><A><R><R><A><E><L><E><K><L><A><A><E><K><K><A><S><A><E><A><R><A><A><Q><L><A><E><L><E><V><T><I><T><A><T><A><G><D><E><G><K><L><F><G><S><I><G><T><H><D><I><A><D><A><L><T><A><S><G><V... | Binds to the 23S rRNA.<BOP> | A4XQ00 |
F1MRW8 | RN169_BOVIN | RING-type E3 ubiquitin transferase RNF169 | Bos | <M><S><G><R><A><K><V><A><G><E><E><A><L><V><G><V><A><A><P><Q><P><V><P><A><G><I><L><D><E><C><T><N><V><T><V><S><Q><P><P><S><P><P><R><P><E><E><S><D><C><A><G><C><L><E><T><P><G><E><A><A><A><L><P><C><G><H><S><L><C><R><G><C><A><Q><R><A><A><D><A><A><G><P><C><C><P><R><C><R><A><R><G><A><G><W><A><R><R><R><A><R><D><D><W><Q><A><D><A... | Probable E3 ubiquitin-protein ligase that acts as a regulator of double-strand breaks (DSBs) repair following DNA damage. Functions in a non-canonical fashion to harness RNF168-mediated protein recruitment to DSB-containing chromatin, thereby contributing to regulation of DSB repair pathway utilization. Once recruited ... | F1MRW8 |
Q84ND0 | TPS2_ANTMA | Terpenoid synthase Oc15 | Antirrhinum | <M><A><F><C><I><S><Y><V><G><A><L><L><P><C><S><L><S><T><R><T><K><F><A><I><C><H><N><T><S><K><L><H><R><A><A><Y><K><T><S><R><W><N><I><P><G><D><V><G><S><T><P><P><P><S><K><L><H><Q><A><L><C><L><N><E><H><S><L><S><C><M><A><E><L><P><M><D><Y><E><G><K><I><K><E><T><R><H><L><L><H><L><K><G><E><N><D><P><I><E><S><L><I><F><V><D><A><T><L... | Contributes to floral scent emission.<BOP> | Q84ND0 |
Q9VWL5 | INX5_DROME | Innexin inx5 | Sophophora | <M><F><S><A><V><K><P><L><S><K><Y><L><Q><F><K><S><I><R><I><Y><D><S><V><F><T><I><H><S><R><C><T><V><V><I><L><L><T><C><S><L><L><L><S><A><R><Q><Y><F><G><D><P><I><Q><C><I><S><E><E><K><N><I><E><Y><I><Q><S><Y><C><W><T><M><G><T><Y><I><L><K><L><D><D><F><G><D><Q><E><Q><A><L><V><S><P><N><Q><E><V><S><Y><N><S><A><F><F><S><S><A><T><T... | Structural component of the gap junctions.<BOP> | Q9VWL5 |
Q5G8B1 | NDB2T_TITCO | Anionic peptide clone 8 | Tityus | <M><V><S><K><S><L><I><V><L><L><L><V><S><V><L><V><S><T><F><F><T><T><E><A><Y><P><A><S><Y><D><D><D><F><D><A><L><D><D><L><D><D><L><D><L><D><D><L><L><D><L><E><P><A><D><L><V><L><L><D><M><W><A><N><M><L><D><S><Q><D><F><E><D><F><E> | May be an antimicrobial peptide.<BOP> | Q5G8B1 |
O88637 | PCY2_RAT | Phosphorylethanolamine transferase | Rattus | <M><I><R><N><G><H><G><A><G><G><A><A><G><L><K><G><P><G><G><Q><R><T><V><R><V><W><C><D><G><C><Y><D><M><V><H><Y><G><H><S><N><Q><L><R><Q><A><R><A><M><G><D><Y><L><I><V><G><V><H><T><D><E><E><I><A><K><H><K><G><P><P><V><F><T><Q><E><E><R><Y><K><M><V><Q><A><I><K><W><V><D><E><V><V><P><A><A><P><Y><V><T><T><L><E><T><L><D><K><H><N><C... | Ethanolamine-phosphate cytidylyltransferase that catalyzes the second step in the synthesis of phosphatidylethanolamine (PE) from ethanolamine via the CDP-ethanolamine pathway. Phosphatidylethanolamine is a dominant inner-leaflet phospholipid in cell membranes, where it plays a role in membrane function by structurally... | O88637 |
A4WPT1 | NADD_CERS5 | Nicotinate mononucleotide adenylyltransferase | Cereibacter | <M><V><V><G><L><L><G><G><S><F><D><P><P><H><A><G><H><V><H><I><S><L><E><A><L><K><R><F><R><L><D><R><V><W><W><L><V><S><P><G><N><P><L><K><P><R><P><P><A><P><L><P><A><R><L><A><E><A><R><R><L><M><R><H><P><R><V><V><V><T><D><I><E><A><R><L><G><T><R><F><T><A><E><T><L><A><A><L><R><A><R><Y><P><G><V><R><F><V><W><L><M><G><A><D><N><L><A... | Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).<BOP> | A4WPT1 |
Q2YMD1 | PDXH_BRUA2 | Pyridoxal 5'-phosphate synthase | Brucella | <M><E><P><V><K><M><T><N><S><S><D><D><F><T><Q><S><A><E><P><F><K><L><F><A><E><W><L><A><D><A><A><K><S><E><P><N><D><P><N><A><V><A><L><A><T><V><D><P><D><G><L><P><N><V><R><M><V><L><L><K><D><F><D><E><T><G><F><V><F><Y><T><N><Y><E><S><K><K><G><Q><E><I><L><S><A><E><K><A><A><M><C><F><H><W><K><S><L><R><R><Q><V><R><V><R><G><P><V><E... | Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP).<BOP> | Q2YMD1 |
B8HAZ5 | ATP6_PSECP | F-ATPase subunit 6 | Pseudarthrobacter | <M><I><A><L><A><L><P><A><Q><D><S><G><E><F><T><P><P><G><I><N><E><M><H><L><P><A><I><L><P><W><G><A><A><E><G><F><S><K><Q><M><L><L><V><L><L><S><V><V><F><I><A><V><F><F><V><L><A><A><R><K><Q><Q><L><V><P><G><K><L><Q><F><A><G><E><A><A><Y><G><F><V><R><N><G><I><A><K><D><I><I><G><G><R><D><F><I><K><Y><V><P><L><L><F><S><L><F><F><F><I... | Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.<BOP> | B8HAZ5 |
Q7VQL3 | DNAJ_BLOFL | Chaperone protein DnaJ | Candidatus Blochmannia | <M><V><K><S><D><Y><Y><E><I><L><G><V><S><K><N><A><D><E><R><E><I><K><K><S><Y><K><R><L><A><M><K><F><H><P><D><R><N><P><G><D><V><S><A><E><S><K><F><K><E><I><K><E><A><Y><E><V><L><S><N><P><E><K><R><S><A><Y><D><Q><Y><G><H><A><I><F><E><Q><N><S><G><G><M><G><G><S><N><T><G><G><S><D><F><S><D><I><F><G><D><V><F><G><D><I><F><G><G><S><R... | Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bou... | Q7VQL3 |
Q88D09 | MCPQ_PSEPK | Methyl-accepting chemotaxis protein McpQ | Pseudomonas | <M><Y><Q><W><L><A><Q><S><L><G><N><V><S><V><N><R><K><L><G><L><G><F><G><L><V><L><L><L><T><L><A><I><T><L><T><G><W><H><G><M><D><S><I><I><D><R><G><D><K><L><G><N><I><S><V><I><Q><Q><Y><T><Q><E><L><R><I><A><R><Q><Q><Y><D><R><R><R><D><D><A><S><L><A><E><L><E><K><A><L><S><N><L><D><R><Q><V><Q><L><M><L><G><Q><I><E><Q><P><A><D><H><Q... | Chemotactic-signal transducers respond to changes in the concentration of attractants and repellents in the environment, transduce a signal from the outside to the inside of the cell, and facilitate sensory adaptation through the variation of the level of methylation. McpQ recognizes specifically citrate and citrate/me... | Q88D09 |
A7IGG9 | THIE_XANP2 | Thiamine-phosphate pyrophosphorylase | Xanthobacter | <M><P><K><P><F><D><L><T><L><Y><L><V><T><D><P><R><L><V><A><A><R><G><L><L><T><T><V><D><A><A><V><K><G><G><A><T><I><V><Q><L><R><D><P><D><A><H><G><R><A><L><V><E><Q><A><R><A><L><K><A><L><L><A><P><L><G><I><P><L><I><I><N><D><R><V><D><V><A><V><A><A><D><A><D><G><V><H><L><G><Q><D><D><M><T><P><A><D><A><R><A><V><L><G><P><Q><R><I><L... | Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP).<BOP> | A7IGG9 |
P25437 | FRMA_ECOLI | Glutathione-dependent formaldehyde dehydrogenase | Escherichia | <M><K><S><R><A><A><V><A><F><A><P><G><K><P><L><E><I><V><E><I><D><V><A><P><P><K><K><G><E><V><L><I><K><V><T><H><T><G><V><C><H><T><D><A><F><T><L><S><G><D><D><P><E><G><V><F><P><V><V><L><G><H><E><G><A><G><V><V><V><E><V><G><E><G><V><T><S><V><K><P><G><D><H><V><I><P><L><Y><T><A><E><C><G><E><C><E><F><C><R><S><G><K><T><N><L><C><V... | Has high formaldehyde dehydrogenase activity in the presence of glutathione and catalyzes the oxidation of normal alcohols in a reaction that is not GSH-dependent. In addition, hemithiolacetals other than those formed from GSH, including omega-thiol fatty acids, also are substrates.<BOP> | P25437 |
P46606 | HD1_BRANA | Homeobox protein HD1 | Brassica | <M><Q><E><A><A><L><G><M><I><G><A><T><V><G><G><G><G><D><G><D><A><A><V><V><A><E><Q><N><R><Q><M><K><G><E><I><A><T><H><P><M><Y><D><Q><L><L><A><A><H><V><A><C><L><R><V><A><T><P><I><D><Q><L><P><I><I><E><A><Q><L><S><H><S><H><H><L><L><R><S><Y><A><S><T><A><V><G><F><S><H><H><D><R><Q><E><L><D><N><F><L><A><Q><Y><V><M><V><L><C><S><F... | Possible developmental regulator.<BOP> | P46606 |
Q494C2 | ATPE_BLOPB | F-ATPase epsilon subunit | Candidatus Blochmannia | <M><S><E><C><T><Y><Y><L><T><V><V><S><V><E><R><E><I><F><S><G><V><V><R><K><I><Q><V><T><G><I><E><G><E><M><G><V><F><P><G><H><T><P><L><L><T><S><I><K><P><G><V><L><R><I><V><K><S><H><D><N><E><E><Y><I><Y><I><S><G><G><I><L><E><V><Q><R><N><I><V><T><I><L><A><D><T><A><I><R><A><E><E><L><D><E><K><K><A><K><E><A><K><H><E><A><E><K><H><I... | Produces ATP from ADP in the presence of a proton gradient across the membrane.<BOP> | Q494C2 |
Q662I1 | FLIW_BORGP | Flagellar assembly factor FliW | Borreliella | <M><I><N><E><K><S><I><G><F><D><F><P><E><G><I><L><G><F><E><N><I><K><K><F><I><I><K><D><S><K><Y><K><P><F><S><I><M><Q><S><I><N><K><E><V><S><F><L><V><T><S><P><F><N><F><L><S><E><Y><L><P><N><I><Q><E><K><D><W><S><D><I><K><A><K><E><E><D><E><R><V><I><L><C><I><I><N><M><H><V><N><D><Y><K><D><I><T><A><N><L><K><A><P><I><I><I><N><K><K... | Acts as an anti-CsrA protein, binds CsrA and prevents it from repressing translation of its target genes, one of which is flagellin. Binds to flagellin and participates in the assembly of the flagellum.<BOP> | Q662I1 |
P35852 | PURL_LACCA | Phosphoribosylformylglycinamidine synthase subunit II | Lacticaseibacillus | <M><Y><V><V><H><V><E><M><S><P><E><A><I><A><T><Q><K><P><Y><L><D><L><G><L><T><E><A><E><Y><D><R><F><A><E><L><I><G><H><Q><P><N><D><T><E><I><G><L><A><S><G><M><W><S><E><H><C><A><Y><K><Y><S><K><P><V><L><R><Q><F><W><T><K><N><E><R><V><L><M><G><P><G><E><G><A><G><V><I><D><I><G><E><G><K><A><V><V><F><K><A><E><S><H><N><H><P><S><A><V... | Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three su... | P35852 |
Q2NHQ3 | CBIA_METST | Ni-sirohydrochlorin a,c-diamide synthetase | Methanosphaera | <M><K><R><V><V><L><T><G><T><G><S><G><V><G><K><T><T><I><A><T><G><I><M><K><A><L><S><D><E><H><K><I><Q><P><F><K><V><G><P><D><Y><I><D><P><S><Y><H><N><C><A><T><G><V><S><S><R><N><L><D><S><F><F><M><S><D><G><Q><I><R><Q><S><F><K><N><G><M><T><S><S><H><A><D><Y><G><I><I><E><G><V><R><G><L><Y><E><G><I><S><P><T><N><D><I><G><S><T><S><S... | Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source. Involved in the biosynthesis of the unique nickel-containing tetrapyrrole coenzyme F430, the prosthetic group of methyl-coenzyme M reductase (MCR), which pl... | Q2NHQ3 |
B6JNC0 | TRPD_HELP2 | Anthranilate phosphoribosyltransferase | Helicobacter | <M><K><E><I><L><N><A><L><Y><H><Q><K><D><L><S><D><K><E><V><K><K><L><F><T><L><I><I><H><E><K><V><S><P><V><Q><L><G><A><I><L><C><A><L><K><I><K><G><E><S><F><K><E><I><S><V><A><A><T><T><L><L><E><H><A><P><K><P><F><D><S><G><L><D><L><I><D><N><C><G><T><G><G><D><G><L><K><T><I><N><I><S><T><I><A><A><L><I><A><S><S><M><G><L><S><M><A><K... | Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).<BOP> | B6JNC0 |
Q6D159 | UPPP_PECAS | Undecaprenyl pyrophosphate phosphatase | Pectobacterium | <M><T><D><L><H><S><L><L><I><A><F><I><L><G><V><V><E><G><L><T><E><F><L><P><V><S><S><T><G><H><M><I><I><V><G><H><W><L><G><F><V><D><E><K><A><K><T><F><E><V><I><I><Q><L><G><S><I><L><A><V><V><V><M><F><W><R><R><L><F><G><L><I><G><I><H><F><G><K><V><P><H><E><G><K><T><S><G><R><L><K><L><T><H><I><L><L><A><M><I><P><A><V><V><L><G><L><I... | Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin.<BOP> | Q6D159 |
A5WG13 | ENO_PSYWF | 2-phosphoglycerate dehydratase | Psychrobacter | <M><Y><A><E><N><I><T><N><A><V><E><I><Q><D><I><R><A><R><E><I><L><D><S><R><G><N><P><T><I><E><A><D><V><I><L><A><D><G><S><M><G><R><A><A><A><P><S><G><A><S><T><G><S><R><E><A><L><E><L><R><D><G><D><K><S><R><Y><L><G><K><G><V><T><K><A><V><A><N><V><N><S><Q><I><R><S><A><L><L><E><S><D><A><T><D><Q><Q><G><I><D><N><I><L><I><E><L><D><G... | Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.<BOP> | A5WG13 |
Q2I2R5 | CLE1_CONLT | Alpha-conotoxin LtXIVA | Elisaconus | <M><K><L><S><V><M><F><I><V><F><L><M><L><T><M><P><M><T><C><A><G><I><S><R><S><A><T><N><G><G><E><A><D><V><R><A><H><D><K><A><A><N><L><M><A><L><L><Q><E><R><M><C><P><P><L><C><K><P><S><C><T><N><C><G> | Alpha-conotoxins act on postsynaptic membranes, they bind to the nicotinic acetylcholine receptors (nAChR) and thus inhibit them . This synthetic peptide displays analgesic activity in a hot plate assay . Analgesia is also observed against second phase pain in formalin-induced inflammatory pain model, and in a rat mode... | Q2I2R5 |
Q3JE31 | CCA_NITOC | Phosphatase | Nitrosococcus | <M><E><V><Y><L><V><G><G><A><V><R><D><K><L><L><G><R><P><V><K><E><R><D><Y><V><V><V><G><T><T><P><A><N><L><L><A><Q><G><Y><R><P><V><G><K><D><F><P><V><F><L><H><P><Q><T><Q><E><E><Y><A><L><A><R><T><E><R><K><T><G><P><G><Y><K><G><F><E><V><D><A><A><P><D><V><T><L><E><E><D><L><Q><R><R><D><L><T><I><N><A><I><A><E><A><A><D><G><S><L><L... | Catalyzes the addition and repair of the essential 3'-terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate. Also shows phosphatase, 2'-nucleotidase a... | Q3JE31 |
A7MPG4 | RS8_CROS8 | 30S ribosomal protein S8 | Cronobacter | <M><S><M><Q><D><P><I><A><D><M><L><T><R><I><R><N><G><Q><A><A><N><K><A><A><V><T><M><P><S><S><K><L><K><V><A><I><A><N><V><L><K><E><E><G><F><I><E><D><F><K><V><E><G><D><T><K><P><E><L><E><L><T><L><K><Y><F><Q><G><K><A><V><V><E><S><I><Q><R><V><S><R><P><G><L><R><I><Y><K><K><K><D><E><L><P><K><V><M><A><G><L><G><I><A><V><I><S><T><S... | One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.<BOP> | A7MPG4 |
B7IRS8 | UNG_BACC2 | Uracil-DNA glycosylase | Bacillus cereus group | <M><E><N><V><L><R><N><D><W><G><P><L><L><A><P><E><F><E><K><E><Y><Y><L><T><L><S><S><F><L><T><E><E><Y><S><T><H><V><V><Y><P><K><V><E><D><I><F><N><A><L><Q><Y><T><S><Y><E><N><T><K><V><V><I><L><G><Q><D><P><Y><H><G><P><N><Q><A><H><G><L><S><F><S><V><Q><P><G><V><K><T><P><P><S><L><L><N><M><Y><K><E><L><R><D><E><Y><G><Y><E><I><P><N... | Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.<BOP> | B7IRS8 |
Q11GG5 | GREA_CHESB | Transcript cleavage factor GreA | unclassified Chelativorans | <M><N><K><V><P><M><T><L><A><G><Y><E><S><L><K><E><E><L><R><W><R><Q><Q><E><E><R><P><R><I><I><E><A><I><A><E><A><R><A><H><G><D><L><S><E><N><A><E><Y><H><A><A><K><E><A><Q><S><L><N><E><G><R><I><S><E><L><E><D><L><I><A><R><A><E><V><I><D><V><T><K><L><S><G><D><T><V><K><F><G><A><T><V><V><L><V><D><E><D><T><E><E><E><K><T><Y><Q><I><V... | Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factor... | Q11GG5 |
A8AYI5 | ARGB_STRGC | NAG kinase | Streptococcus | <M><K><D><V><I><V><I><K><I><G><G><V><A><A><K><K><L><S><D><K><F><I><K><Q><M><Q><E><W><I><A><A><G><K><K><I><V><V><V><H><G><G><G><L><V><I><N><Q><L><M><K><E><R><Q><L><P><T><R><K><V><K><G><L><R><V><T><A><K><S><D><L><P><I><I><Q><Q><A><L><L><G><Q><V><G><R><T><L><T><Q><E><L><N><Y><S><D><I><E><S><L><Q><L><V><S><H><L><G><K><T><V... | Catalyzes the ATP-dependent phosphorylation of N-acetyl-L-glutamate.<BOP> | A8AYI5 |
Q636L3 | IF2_BACCZ | Translation initiation factor IF-2 | Bacillus cereus group | <M><S><K><I><R><V><H><E><Y><A><K><K><H><N><I><S><S><K><D><L><M><T><K><L><K><E><M><N><I><E><V><S><N><H><M><T><M><L><D><D><E><V><V><N><K><L><D><N><E><Y><Q><A><E><K><P><S><V><A><D><E><F><E><V><E><E><K><V><V><R><S><K><K><N><S><N><K><K><K><K><K><G><K><G><N><E><D><K><R><Q><E><N><F><A><G><R><Q><Q><T><Q><T><V><E><T><P><D><K><I... | One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.<BOP> | Q636L3 |
A1TJT2 | RL6_ACIAC | 50S ribosomal protein L6 | Acidovorax | <M><S><R><V><G><K><M><P><V><A><I><P><N><G><V><D><V><T><I><T><E><E><Q><I><S><V><K><G><S><G><G><T><L><S><V><A><Q><N><R><L><V><K><I><V><N><K><D><G><K><L><S><F><E><P><A><D><E><S><R><E><A><N><A><M><S><G><T><I><R><Q><L><V><N><N><M><V><V><G><V><S><K><G><F><E><K><K><L><N><L><I><G><V><G><Y><K><A><Q><A><S><G><A><K><L><N><L><A><V... | This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.<BOP> | A1TJT2 |
Q885J7 | ASTD_PSESM | Succinylglutamic semialdehyde dehydrogenase | Pseudomonas | <M><S><T><L><Y><I><A><G><A><W><Q><A><G><Q><G><E><L><F><H><S><L><N><P><V><T><L><H><V><L><W><S><G><Q><G><A><T><A><E><Q><V><D><H><A><V><Q><A><A><R><Q><A><F><P><A><W><A><L><L><S><L><D><Q><R><I><A><V><L><D><A><F><A><V><S><L><K><A><H><A><D><E><L><A><N><C><I><G><E><E><T><G><K><P><L><W><E><S><A><T><E><V><T><S><M><V><N><K><I><A... | Catalyzes the NAD-dependent reduction of succinylglutamate semialdehyde into succinylglutamate.<BOP> | Q885J7 |
Q9P359 | PGLR2_ASPAW | Polygalacturonase X2 | Aspergillus | <M><H><S><F><A><S><L><L><R><Y><G><L><A><A><G><A><T><L><A><S><A><S><P><I><E><A><R><D><S><C><T><F><T><T><A><A><A><A><K><A><G><K><A><K><C><S><T><I><T><L><D><S><I><K><V><P><A><G><T><T><L><D><L><T><G><L><T><S><G><T><K><V><I><F><E><G><T><T><T><F><D><Y><E><D><W><A><G><P><L><I><S><M><S><G><K><D><I><T><V><T><G><A><S><G><H><L><I... | Involved in maceration and soft-rotting of plant tissue. Hydrolyzes the 1,4-alpha glycosidic bonds of de-esterified pectate in the smooth region of the plant cell wall.<BOP> | Q9P359 |
P23833 | SCO1_YEAST | Protein SCO1, mitochondrial | Saccharomyces | <M><L><K><L><S><R><S><A><N><L><R><L><V><Q><L><P><A><A><R><L><S><G><N><G><A><K><L><L><T><Q><R><G><F><F><T><V><T><R><L><W><Q><S><N><G><K><K><P><L><S><R><V><P><V><G><G><T><P><I><K><D><N><G><K><V><R><E><G><S><I><E><F><S><T><G><K><A><I><A><L><F><L><A><V><G><G><A><L><S><Y><F><F><N><R><E><K><R><R><L><E><T><Q><K><E><A><E><A><N... | Required for the accumulation of subunits 1 and 2 of cytochrome c oxidase complex. Thought to play a role in either mitochondrial copper transport or insertion of copper into the active site of COX.<BOP> | P23833 |
C5CHW7 | ARGC_KOSOT | N-acetyl-glutamate semialdehyde dehydrogenase | Kosmotoga | <M><I><R><V><G><I><I><G><A><T><G><Y><T><G><L><E><L><V><R><I><L><T><N><H><P><D><V><K><I><T><F><L><S><S><R><S><F><A><G><K><K><L><N><D><V><Y><P><F><S><L><K><N><E><T><L><E><E><I><D><P><E><K><I><S><K><N><C><D><V><V><F><T><A><L><P><A><G><V><S><Y><E><I><A><R><K><L><K><D><V><R><I><I><D><L><G><A><D><F><R><F><D><D><P><A><V><Y><E... | Catalyzes the NADPH-dependent reduction of N-acetyl-5-glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde.<BOP> | C5CHW7 |
W6Q2D7 | IFGG_PENRF | Old yellow enzyme homolog ifgG | Penicillium | <M><T><I><I><P><K><H><P><S><P><T><L><F><K><P><L><A><L><G><K><C><Q><L><Q><H><R><I><V><M><S><P><T><T><R><Y><R><A><D><E><A><A><V><P><L><P><F><V><K><E><Y><Y><A><Q><R><A><S><D><P><G><A><L><L><I><T><E><A><T><N><I><C><P><N><S><V><G><E><A><H><I><P><G><I><W><S><K><T><Q><C><E><A><W><R><E><V><V><S><Q><V><H><A><K><E><C><Y><I><F><C... | Chanoclavine-I aldehyde reductase; part of the gene cluster that mediates the biosynthesis of isofumigaclavines, fungal ergot alkaloids . The tryptophan dimethylallyltransferase ifgA catalyzes the first step of ergot alkaloid biosynthesis by condensing dimethylallyl diphosphate (DMAP) and tryptophan to form 4-dimethyla... | W6Q2D7 |
A6V1E5 | LPXB_PSEA7 | Lipid-A-disaccharide synthase | Pseudomonas | <M><A><G><R><L><R><V><A><L><V><A><G><E><A><S><G><D><I><L><G><S><G><L><M><Q><A><L><R><A><R><H><P><E><I><E><F><I><G><V><G><G><P><R><M><E><A><E><G><L><S><S><Y><F><P><M><E><R><L><S><V><M><G><L><V><E><V><L><G><R><L><P><E><L><L><R><R><R><K><R><L><I><R><T><L><I><D><A><R><P><D><V><M><I><G><I><D><A><P><D><F><T><L><G><V><E><H><R... | Condensation of UDP-2,3-diacylglucosamine and 2,3-diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.<BOP> | A6V1E5 |
O55091 | IMPCT_MOUSE | Imprinted and ancient gene protein | Mus | <M><A><E><E><E><V><G><N><S><Q><R><Q><S><E><E><I><E><A><M><A><A><I><Y><G><E><E><W><C><V><I><D><E><N><A><K><I><F><C><I><R><V><T><D><F><M><D><D><P><K><W><T><L><C><L><Q><V><M><L><P><S><E><Y><P><G><T><A><P><P><S><Y><Q><L><N><A><P><W><L><K><G><Q><E><R><A><D><L><S><N><S><L><E><E><I><Y><V><H><N><M><G><E><S><I><L><Y><Q><W><V><E... | Translational regulator that ensures constant high levels of translation upon a variety of stress conditions, such as amino acid starvation, UV-C irradiation, proteasome inhibitor treatment and glucose deprivation. Plays a role as a negative regulator of the EIF2AK4/GCN2 kinase activity; impairs GCN1-mediated EIF2AK4/G... | O55091 |
Q3AZE2 | SYY_SYNS9 | Tyrosyl-tRNA synthetase | unclassified Synechococcus | <M><P><E><T><N><P><S><L><P><S><W><L><N><R><G><M><A><D><L><F><P><A><G><E><P><S><D><V><D><Q><S><L><A><A><R><L><A><A><A><E><A><E><G><R><P><L><R><V><K><L><G><I><D><P><T><G><S><N><I><H><L><G><H><S><I><L><F><R><K><L><R><A><F><Q><D><A><G><H><I><A><V><L><I><I><G><D><F><T><A><R><I><G><D><P><T><G><K><S><A><T><R><V><Q><L><S><K><N... | Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).<BOP> | Q3AZE2 |
B5FA77 | RIMP_ALIFM | Ribosome maturation factor RimP | Aliivibrio | <M><T><G><L><E><R><Q><L><T><E><M><L><E><A><P><V><G><A><L><G><Y><E><L><V><G><L><E><F><V><R><A><G><E><H><S><T><L><R><V><F><I><D><H><E><N><G><I><F><V><E><D><C><A><E><A><S><R><Q><I><S><A><V><M><D><V><E><D><P><I><T><V><A><Y><N><L><E><V><S><S><P><G><L><E><R><P><L><F><K><A><A><H><Y><Q><Q><F><V><G><H><E><V><S><L><V><L><K><M><P... | Required for maturation of 30S ribosomal subunits.<BOP> | B5FA77 |
A6GWU1 | EFTS_FLAPJ | Elongation factor Ts | Flavobacterium | <M><A><T><I><T><A><A><D><V><N><K><L><R><T><I><T><G><A><G><M><M><D><C><K><K><A><L><V><E><S><D><G><D><F><D><L><A><I><E><N><L><R><K><K><G><Q><K><V><A><A><N><R><S><D><R><E><S><T><E><G><A><A><I><A><V><V><N><A><D><N><T><V><G><V><V><I><T><L><N><C><E><T><D><F><V><G><M><N><E><N><F><V><K><M><A><V><E><M><A><N><L><A><L><N><F><N><N... | Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome.<BOP> | A6GWU1 |
B4RVY8 | DXS_ALTMD | 1-deoxyxylulose-5-phosphate synthase | Alteromonas | <M><S><L><D><L><Q><H><Y><P><T><L><A><L><A><Q><T><P><D><K><L><R><Q><L><P><Q><D><K><L><R><E><L><A><D><E><L><R><E><Y><L><L><N><S><V><S><Q><T><S><G><H><F><A><S><G><L><G><T><V><E><L><T><V><A><L><H><Y><V><Y><N><T><P><F><D><R><L><L><W><D><V><G><H><Q><A><Y><P><H><K><I><L><T><G><R><A><E><R><M><S><T><I><R><Q><K><N><G><L><H><P><F... | Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP).<BOP> | B4RVY8 |
B1X9L5 | FADI_ECODH | Fatty acid oxidation complex subunit beta | Escherichia | <M><G><Q><V><L><P><L><V><T><R><Q><G><D><R><I><A><I><V><S><G><L><R><T><P><F><A><R><Q><A><T><A><F><H><G><I><P><A><V><D><L><G><K><M><V><V><G><E><L><L><A><R><S><E><I><P><A><E><V><I><E><Q><L><V><F><G><Q><V><V><Q><M><P><E><A><P><N><I><A><R><E><I><V><L><G><T><G><M><N><V><H><T><D><A><Y><S><V><S><R><A><C><A><T><S><F><Q><A><V><A... | Catalyzes the final step of fatty acid oxidation in which acetyl-CoA is released and the CoA ester of a fatty acid two carbons shorter is formed.<BOP> | B1X9L5 |
Q5MBR3 | NCED5_ORYSJ | 9-cis-epoxycarotenoid dioxygenase NCED5, chloroplastic | Oryza sativa | <M><P><T><T><F><T><P><N><S><P><A><S><S><C><S><I><H><H><R><A><S><P><S><R><G><A><R><N><S><V><R><F><T><R><P><R><A><A><A><A><A><T><N><S><V><L><S><A><P><S><S><V><P><P><A><Y><V><P><P><P><P><P><P><P><T><K><M><F><P><E><A><G><D><A><A><A><A><K><A><A><A><R><R><C><G><K><K><K><D><G><L><N><F><F><Q><R><A><A><A><V><A><L><D><A><F><E><E... | Has a 11,12(11',12') 9-cis epoxycarotenoid cleavage activity. Catalyzes the first step of abscisic-acid biosynthesis from carotenoids.<BOP> | Q5MBR3 |
O33347 | RELF_MYCTU | Antitoxin RelF | Mycobacterium tuberculosis complex | <M><R><I><L><P><I><S><T><I><K><G><K><L><N><E><F><V><D><A><V><S><S><T><Q><D><Q><I><T><I><T><K><N><G><A><P><A><A><V><L><V><G><A><D><E><W><E><S><L><Q><E><T><L><Y><W><L><A><Q><P><G><I><R><E><S><I><A><E><A><D><A><D><I><A><S><G><R><T><Y><G><E><D><E><I><R><A><E><F><G><V><P><R><R><P><H> | Induces its own promoter, in combination with RelG represses its own promoter. Has been seen to bind DNA in complex with toxin RelG but not alone.<BOP> | O33347 |
Q8CN53 | LRGB_STAES | Antiholin-like protein LrgB | Staphylococcus | <M><I><E><H><L><G><I><N><T><P><Y><F><G><I><L><V><S><L><I><P><F><V><I><A><T><Y><F><Y><K><K><T><N><G><F><F><L><L><A><P><L><F><V><S><M><V><A><G><I><A><F><L><K><L><T><G><I><S><Y><E><N><Y><K><I><G><G><D><I><I><N><F><F><L><E><P><A><T><I><C><F><A><I><P><L><Y><R><K><R><E><V><L><K><R><Y><W><L><Q><I><F><G><G><I><A><V><G><T><I><I... | Inhibits the expression or activity of extracellular murein hydrolases by interacting, possibly with LrgA, with the holin-like proteins CidA and/or CidB. The LrgAB and CidAB proteins may affect the proton motive force of the membrane. May be involved in programmed cell death (PCD), possibly triggering PCD in response t... | Q8CN53 |
Q6DGF6 | F220A_RAT | STAT3-interacting protein as a repressor | Rattus | <M><R><A><G><R><G><T><L><G><V><C><L><A><S><V><K><Q><S><Q><G><G><D><L><D><K><L><A><C><G><L><K><R><R><S><E><K><R><N><P><S><P><S><D><V><P><S><W><T><D><Q><P><V><A><D><T><H><G><K><S><R><A><M><A><A><A><S><S><E><M><K><R><D><Q><S><K><A><S><L><I><L><H><S><G><F><K><A><L><Q><Y><L><K><E><S><M><G><R><N><S><T><P><A><A><S><L><S><M><A... | May negatively regulate STAT3.<BOP> | Q6DGF6 |
Q1WTT3 | PFKA_LIGS1 | Phosphohexokinase | Ligilactobacillus | <M><K><R><I><G><I><L><T><S><G><G><D><A><A><G><M><N><A><A><V><R><A><I><A><R><S><A><M><N><A><G><L><E><A><Y><G><I><N><Y><G><Y><K><G><L><V><E><G><N><I><F><K><M><E><S><T><K><L><D><E><I><I><N><R><G><G><T><I><L><Y><S><A><R><F><P><E><F><A><E><T><E><T><Q><L><K><G><I><E><Q><L><K><K><F><G><I><E><A><L><V><V><I><G><G><D><G><S><Y><H... | Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.<BOP> | Q1WTT3 |
Q057J0 | OBG_BUCCC | GTP-binding protein Obg | Buchnera | <M><K><F><V><D><S><V><I><I><N><V><S><A><G><K><G><G><D><G><C><I><S><F><R><R><E><K><F><V><P><K><G><G><P><D><G><G><N><G><G><D><G><G><N><I><W><I><V><S><N><T><N><I><N><T><L><T><D><Y><R><I><K><K><I><F><Q><S><E><N><G><K><N><G><L><N><S><N><R><S><G><K><N><G><K><D><I><Y><I><P><V><P><L><G><T><R><I><I><D><N><D><T><K><K><I><I><I><E... | An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.<B... | Q057J0 |
P06352 | H3_STRPU | Histone H3, embryonic | Strongylocentrotus | <M><A><R><T><K><Q><T><A><R><K><S><T><G><G><K><A><P><R><K><Q><L><A><T><K><A><A><R><K><S><A><P><A><T><G><G><V><K><K><P><H><R><Y><R><P><G><T><V><A><L><R><E><I><R><R><Y><Q><K><S><T><E><L><L><I><R><K><L><P><F><Q><R><L><V><R><E><I><A><Q><D><F><K><T><E><L><R><F><Q><S><S><A><V><M><A><L><Q><E><A><S><E><A><Y><L><V><R><L><F><E><D... | Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated v... | P06352 |
O47583 | CYB_MOSMO | Ubiquinol-cytochrome-c reductase complex cytochrome b subunit | Moschus | <M><T><N><I><R><K><S><H><P><L><M><K><I><V><N><N><A><F><I><D><L><P><A><P><S><N><I><S><S><W><W><N><F><G><S><L><L><G><I><C><L><I><L><Q><I><L><T><G><L><F><L><A><M><H><Y><T><S><D><T><M><T><A><F><S><S><V><T><H><I><C><R><D><V><N><Y><G><W><I><I><R><Y><M><H><A><N><G><A><S><M><F><F><I><C><L><F><M><H><V><G><R><G><L><Y><Y><G><S><Y... | Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain. The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c. Contributes to the generation of a proton gradient across the mitochondrial membrane that is... | O47583 |
Q8EMZ1 | RPIA2_OCEIH | Phosphoriboisomerase A 2 | Oceanobacillus | <M><E><Y><S><D><K><Q><I><A><A><Q><E><A><V><R><Y><I><K><D><G><M><V><I><G><I><G><S><G><S><T><V><N><E><F><L><Y><C><L><A><A><R><M><R><K><E><R><L><Q><V><V><G><I><P><A><S><K><K><S><E><R><L><A><T><E><L><G><I><P><L><T><T><F><A><T><Y><Q><N><V><D><I><A><I><D><G><T><D><E><I><D><D><Q><L><Y><L><V><K><G><G><G><G><S><L><V><R><E><K><M... | Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate.<BOP> | Q8EMZ1 |
Q8K363 | DDX18_MOUSE | DEAD box protein 18 | Mus | <M><S><Q><L><Q><M><K><L><L><R><R><K><I><E><K><R><N><A><K><L><R><Q><R><N><L><K><L><Q><E><T><S><D><T><S><L><S><Q><P><Q><N><G><D><V><P><K><E><T><G><K><G><G><K><V><K><K><A><L><K><R><S><V><P><V><D><S><A><E><A><Q><S><G><G><M><P><E><E><T><L><E><N><G><K><V><K><K><S><P><Q><K><L><T><T><L><A><N><G><E><A><A><P><T><P><P><P><D><S><E... | Probable RNA-dependent helicase.<BOP> | Q8K363 |
B6J0W1 | TIG_COXB2 | PPIase | Coxiella | <M><R><G><N><F><M><S><S><I><E><K><L><G><G><L><K><Q><R><L><T><I><T><V><P><A><E><E><V><D><K><A><Y><K><S><R><L><L><K><V><A><R><T><A><K><I><P><K><F><R><P><G><K><A><S><P><A><V><V><E><K><L><Y><G><K><A><I><L><Q><E><V><G><S><E><L><I><Q><S><S><L><R><E><A><V><E><E><H><Q><L><Q><V><A><G><A><P><D><I><K><M><D><K><I><L><R><G><E><P><F... | Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase.<BOP> | B6J0W1 |
Q08HK6 | NU4LM_ZALCA | NADH dehydrogenase subunit 4L | Zalophus | <M><S><M><M><Y><F><N><I><F><M><A><F><T><V><S><L><V><G><L><L><M><Y><R><S><H><L><M><S><S><L><L><C><L><E><G><M><M><L><S><L><F><V><M><M><S><V><T><I><L><N><N><H><F><T><L><A><S><M><A><P><I><I><L><L><V><F><A><A><C><E><A><A><L><G><L><S><L><L><V><M><V><S><N><T><Y><G><T><D><Y><V><Q><N><L><N><L><L><Q><C> | Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) which catalyzes electron transfer from NADH through the respiratory chain, using ubiquinone as an electron acceptor.<BOP> | Q08HK6 |
Q9NUE0 | ZDH18_HUMAN | Zinc finger DHHC domain-containing protein 18 | Homo | <M><K><D><C><E><Y><Q><Q><I><S><P><G><A><A><P><L><P><A><S><P><G><A><R><R><P><G><P><A><A><S><P><T><P><G><P><G><P><A><P><P><A><A><P><A><P><P><R><W><S><S><S><G><S><G><S><G><S><G><S><G><S><L><G><R><R><P><R><R><K><W><E><V><F><P><G><R><N><R><F><Y><C><G><G><R><L><M><L><A><G><H><G><G><V><F><A><L><T><L><L><L><I><L><T><T><T><G><L... | Palmitoyltransferase that catalyzes the addition of palmitate onto various protein substrates, such as CGAS, HRAS and LCK . Acts as a negative regulator of the cGAS-STING pathway be mediating palmitoylation and inactivation of CGAS . May also have a palmitoyltransferase activity toward the beta-2 adrenergic receptor/AD... | Q9NUE0 |
Q19443 | SID5_CAEEL | Systemic RNA interference defective protein 5 | Caenorhabditis | <M><P><S><K><N><C><A><K><N><L><H><A><C><Q><W><E><R><D><I><A><L><V><F><L><G><L><M><V><L><F><N><I><G><Q><V><V><Y><M><N><R><A><R><L><Y><R><L><I><R><R><G><A><E><Q><I><P><A><D><D><E><E><P><I><I><G><I><R><D> | Plays a role in RNA-mediated gene silencing by mediating transport of both ingested and endogenous dsRNA between cells. Not required for the uptake of dsRNA from the intestinal lumen.<BOP> | Q19443 |
Q8ZY36 | HIS1_PYRAE | ATP phosphoribosyltransferase | Pyrobaculum | <M><L><L><A><V><P><S><K><G><R><L><Q><E><P><T><L><K><L><L><E><A><V><G><I><R><P><L><A><S><D><E><R><A><L><V><V><P><T><S><W><S><D><V><N><L><I><R><A><R><P><E><D><I><P><Y><L><V><E><S><G><R><V><W><A><G><I><T><G><H><D><Y><V><V><E><S><G><S><N><V><A><E><V><L><E><L><E><F><G><R><G><K><L><V><V><A><V><P><R><S><S><G><I><T><S><V><E><D... | Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.<BOP> | Q8ZY36 |
B7LEG3 | TRUD_ECO55 | tRNA-uridine isomerase D | Escherichia | <M><I><E><F><D><N><L><T><Y><L><H><G><K><P><Q><G><T><G><L><L><K><A><N><P><E><D><F><V><V><V><E><D><L><G><F><E><P><D><G><E><G><E><H><I><L><V><R><I><L><K><N><G><C><N><T><R><F><V><A><D><A><L><A><K><F><L><K><I><H><A><R><E><V><S><F><A><G><Q><K><D><K><H><A><V><T><E><Q><W><L><C><A><R><V><P><G><K><E><M><P><E><L><S><A><F><Q><L><E... | Responsible for synthesis of pseudouridine from uracil-13 in transfer RNAs.<BOP> | B7LEG3 |
Q88XW5 | KAD_LACPL | Adenylate monophosphate kinase | Lactiplantibacillus | <M><S><T><M><N><L><I><L><M><G><L><P><G><A><G><K><G><T><Q><A><Q><K><I><L><E><D><F><D><I><P><H><I><S><T><G><D><I><F><R><A><A><I><K><N><E><T><K><M><G><L><E><A><K><K><Y><I><D><A><G><N><L><V><P><D><E><V><T><N><G><I><V><R><D><R><L><A><E><A><D><T><K><N><G><F><L><L><D><G><Y><P><R><N><I><D><Q><A><H><A><L><K><Q><I><G><E><E><L><N... | Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.<BOP> | Q88XW5 |
P04803 | SYWM_YEAST | Tryptophanyl-tRNA synthetase | Saccharomyces | <M><S><N><K><Q><A><V><L><K><L><I><S><K><R><W><I><S><T><V><Q><R><A><D><F><K><L><N><S><E><A><L><H><S><N><A><T><V><F><S><M><I><Q><P><T><G><C><F><H><L><G><N><Y><L><G><A><T><R><V><W><T><D><L><C><E><L><K><Q><P><G><Q><E><L><I><F><G><V><A><D><L><H><A><I><T><V><P><K><P><D><G><E><M><F><R><K><F><R><H><E><A><V><A><S><I><L><A><V><G... | Mitochondrial aminoacyl-tRNA synthetase that catalyzes the attachment of tryptophan to tRNA(Trp).<BOP> | P04803 |
Q15VD0 | GLGB_PSEA6 | Glycogen branching enzyme | Pseudoalteromonas | <M><Q><L><E><K><Q><L><Q><H><A><Q><C><T><F><P><F><S><H><L><G><L><L><K><T><D><N><A><F><T><I><T><A><W><V><P><N><A><T><G><I><K><V><I><D><L><A><T><D><K><A><I><G><S><L><K><R><Q><A><Q><S><D><L><F><T><A><E><F><T><K><G><N><P><P><A><V><Y><A><F><E><V><K><N><A><Q><G><S><Y><R><I><I><D><P><Y><Q><F><Q><D><Q><A><F><H><A><V><H><F><V><D... | Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position.<BOP> | Q15VD0 |
A5D3W2 | YBEY_PELTS | Endoribonuclease YbeY | Pelotomaculum | <M><P><V><L><V><S><N><L><Q><G><K><V><A><V><D><E><A><L><T><G><L><L><T><R><A><A><Q><E><V><L><K><A><E><G><Y><G><E><E><A><E><V><S><L><V><F><V><D><D><A><Y><I><H><G><L><N><R><Q><Y><R><G><V><D><A><P><T><D><V><L><S><F><A><M><Q><E><G><E><P><L><A><G><G><E><E><E><L><I><L><G><D><V><V><I><S><L><Q><A><A><E><R><Q><A><G><E><Y><G><H><S... | Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.<BOP> | A5D3W2 |
A4VRN4 | ILVD_PSEU5 | Dihydroxy-acid dehydratase | Pseudomonas | <M><P><D><Y><R><S><K><T><S><T><H><G><R><N><M><A><G><A><R><A><L><W><R><A><T><G><M><K><D><E><D><F><K><K><P><I><I><A><I><A><N><S><F><T><Q><F><V><P><G><H><V><H><L><K><D><M><G><Q><L><V><A><R><E><I><E><K><H><G><G><V><A><K><E><F><N><T><I><A><V><D><D><G><I><A><M><G><H><D><G><M><L><Y><S><L><P><S><R><E><I><I><A><D><S><V><E><Y><M... | Functions in the biosynthesis of branched-chain amino acids. Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (... | A4VRN4 |
Q21K87 | ACP_SACD2 | Acyl carrier protein | Saccharophagus | <M><S><S><I><E><E><R><V><K><K><I><V><A><E><Q><L><G><V><K><E><E><E><V><K><N><E><A><S><F><V><E><D><L><G><A><D><S><L><D><T><V><E><L><V><M><A><L><E><E><E><F><E><T><E><I><P><D><E><E><A><E><K><I><T><T><V><Q><L><A><I><N><Y><I><N><E><N><L><A> | Carrier of the growing fatty acid chain in fatty acid biosynthesis.<BOP> | Q21K87 |
B8DR41 | SAHH_DESVM | S-adenosyl-L-homocysteine hydrolase | Desulfovibrio | <M><T><D><A><K><R><A><Q><A><L><D><L><S><L><A><N><K><V><A><D><M><A><L><A><D><F><G><H><K><E><M><Q><L><S><E><R><E><V><P><G><L><M><E><L><I><R><M><Y><G><V><S><K><P><L><K><G><L><R><V><T><G><S><L><H><M><T><I><Q><T><A><M><L><I><K><T><L><Y><E><L><G><A><D><I><R><W><A><S><C><N><I><F><S><T><Q><D><H><A><A><A><A><I><A><D><S><G><M><A... | May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine.<BOP> | B8DR41 |
Q9S9Z2 | MYB93_ARATH | Myb-related protein 93 | Arabidopsis | <M><G><R><S><P><C><C><D><E><N><G><L><K><K><G><P><W><T><P><E><E><D><Q><K><L><I><D><Y><I><H><K><H><G><H><G><S><W><R><A><L><P><K><L><A><D><L><N><R><C><G><K><S><C><R><L><R><W><T><N><Y><L><R><P><D><I><K><R><G><K><F><S><A><E><E><E><Q><T><I><L><H><L><H><S><I><L><G><N><K><W><S><A><I><A><T><H><L><Q><G><R><T><D><N><E><I><K><N><F... | Transcription factor that acts as negative regulator of lateral root (LR) development. Required for normal auxin responses during LR development. May be part of a negative feedback loop stimulated specifically in the endodermis upon LR initiation to ensure that LRs are formed only in the correct place.<BOP> | Q9S9Z2 |
Q9X9Q0 | HOA_STRTE | 4-hydroxy-2-oxopentanoate aldolase | Streptomyces | <M><S><Q><E><A><A><R><D><A><A><A><G><R><P><V><Q><I><H><D><P><T><L><R><D><G><Q><H><A><V><R><H><S><L><G><A><E><Q><F><R><A><Y><L><K><A><A><D><A><A><A><V><P><V><V><E><V><G><H><G><N><G><L><A><A><S><S><L><Q><V><G><R><A><R><L><S><D><D><E><M><M><S><I><A><R><E><T><L><T><T><S><K><L><G><V><L><M><F><P><G><W><A><T><T><Q><D><I><K><N... | Involved in the biosynthesis of the peptidyl nucleoside antibiotic nikkomycin.<BOP> | Q9X9Q0 |
Q9AB66 | ATPF_CAUVC | F-type ATPase subunit b | Caulobacter | <M><E><H><Q><S><L><F><S><F><S><N><P><E><F><W><V><L><A><A><L><V><I><F><F><G><L><L><V><V><L><K><V><L><P><G><A><L><F><G><A><L><D><G><Y><A><A><K><I><K><A><E><L><D><E><A><Q><Q><L><R><E><E><A><Q><A><L><L><A><D><V><K><A><Q><R><E><D><A><E><R><Q><A><A><A><M><L><E><A><A><K><A><D><A><K><R><L><A><E><E><A><K><E><K><L><E><E><Q><I><K... | Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0).<BOP> | Q9AB66 |
B5XPH8 | SBMC_KLEP3 | DNA gyrase inhibitor | Klebsiella | <M><N><Y><S><I><T><T><L><G><K><K><T><I><A><G><F><H><L><V><G><P><W><D><Q><T><V><K><Q><G><V><E><Q><L><M><M><W><V><E><N><H><Q><V><P><A><R><E><W><L><A><V><Y><Y><D><N><P><E><E><V><P><A><E><K><L><R><C><A><T><V><V><A><V><D><E><D><Y><V><I><P><A><N><S><E><G><V><I><L><A><A><V><A><G><G><D><Y><A><C><A><R><A><R><V><V><D><Y><D><F><A... | Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the ce... | B5XPH8 |
Q8KA20 | RNFB_BUCAP | Rnf electron transport complex subunit B | Buchnera | <M><S><I><T><I><I><L><I><F><S><I><L><S><F><L><L><G><I><I><L><S><Y><V><K><Y><I><F><P><I><K><K><N><S><I><I><A><E><V><D><D><L><L><P><Q><S><Q><C><A><Q><C><G><Y><S><G><C><Y><P><Y><A><K><A><I><V><K><N><N><E><N><I><D><K><C><I><P><G><G><N><N><L><K><F><K><I><A><K><V><L><N><I><K><N><I><K><Y><S><L><D><N><L><N><A><K><N><E><K><N><I... | Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.<BOP> | Q8KA20 |
Q4KHS7 | MLTF_PSEF5 | Murein lyase F | Pseudomonas | <M><F><S><P><M><A><L><R><P><R><C><A><K><W><L><I><V><T><G><L><F><L><M><L><G><A><C><V><E><K><P><S><T><L><E><R><V><K><E><D><G><V><L><R><V><V><T><R><N><S><P><A><T><Y><F><Q><D><R><N><G><E><T><G><F><E><Y><E><L><V><K><R><F><A><D><D><L><G><V><E><L><K><I><E><T><A><D><N><L><D><D><L><F><D><Q><L><G><Q><P><K><G><P><V><L><A><A><A><G... | Murein-degrading enzyme that degrades murein glycan strands and insoluble, high-molecular weight murein sacculi, with the concomitant formation of a 1,6-anhydromuramoyl product. Lytic transglycosylases (LTs) play an integral role in the metabolism of the peptidoglycan (PG) sacculus. Their lytic action creates space wit... | Q4KHS7 |
A5FL33 | ATPD_FLAJ1 | F-type ATPase subunit delta | Flavobacterium | <M><A><S><T><R><A><A><I><R><Y><A><K><A><I><L><D><L><A><N><S><K><G><V><A><E><A><V><N><N><D><M><K><S><I><A><S><A><I><E><T><N><T><E><L><S><T><F><I><Q><N><P><T><T><T><V><E><V><K><E><S><A><L><L><E><V><F><A><D><V><N><G><V><T><K><G><L><F><H><L><L><F><E><N><K><R><F><E><I><L><D><A><I><A><V><E><Y><N><K><L><F><D><E><S><N><G><V><E... | This protein is part of the stalk that links CF(0) to CF(1). It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.<BOP> | A5FL33 |
B4S096 | RL22_ALTMD | 50S ribosomal protein L22 | Alteromonas | <M><E><A><L><A><K><H><R><F><A><R><T><S><A><Q><K><A><R><L><V><A><D><Q><I><R><G><L><H><V><E><K><A><L><E><V><L><A><Y><S><P><K><K><S><A><A><L><V><K><K><V><L><E><S><A><I><A><N><A><E><H><N><E><G><A><D><I><D><E><L><V><V><A><K><V><F><V><D><E><G><P><T><M><K><R><I><K><P><R><A><K><G><R><A><D><R><I><F><K><R><S><S><H><I><T><V><V><V... | The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.<BOP> | B4S096 |
Q8BPG6 | SUMF2_MOUSE | Sulfatase-modifying factor 2 | Mus | <M><R><S><E><F><W><F><P><S><M><G><S><L><L><P><P><V><L><L><L><W><L><L><S><C><P><R><L><Q><L><G><H><A><Q><D><P><A><M><V><H><L><P><G><G><R><F><L><M><G><T><D><A><P><D><G><R><D><G><E><G><P><A><R><E><V><T><V><K><P><F><A><I><D><I><F><P><V><T><N><K><D><F><R><E><F><V><R><E><K><K><Y><Q><T><E><A><E><A><F><G><W><S><F><V><F><E><D><F... | Lacks formylglycine generating activity and is unable to convert newly synthesized inactive sulfatases to their active form. Inhibits the activation of sulfatases by SUMF1.<BOP> | Q8BPG6 |
Q06637 | BFSP1_CHICK | Filensin N-terminal fragment | Gallus | <M><Y><R><S><S><F><L><R><E><V><R><K><E><K><Y><E><R><S><D><A><Y><D><E><L><R><G><S><P><E><F><D><S><L><A><Q><A><Q><G><L><E><N><L><Q><E><L><N><E><R><F><A><S><Y><I><N><R><A><R><V><L><E><Q><R><N><T><I><L><R><K><Q><L><E><T><F><Q><R><M><D><E><L><V><G><L><D><E><A><F><A><G><Q><I><E><F><N><R><Q><R><M><R><E><L><A><S><D><R><A><K><L... | Required for the correct formation of lens intermediate filaments.<BOP> | Q06637 |
Q5JIZ5 | TKSP_THEKO | Tk-SP | Thermococcus | <M><K><K><F><G><A><V><V><L><A><L><F><L><V><G><L><M><A><G><S><V><L><A><A><P><Q><K><P><A><V><R><N><V><S><Q><Q><K><N><Y><G><L><L><T><P><G><L><F><K><K><V><Q><R><M><S><W><D><Q><E><V><S><T><I><I><M><F><D><N><Q><A><D><K><E><K><A><V><E><I><L><D><F><L><G><A><K><I><K><Y><N><Y><H><I><I><P><A><L><A><V><K><I><K><V><K><D><L><L><I><I... | Serine protease with a broad substrate specificity.<BOP> | Q5JIZ5 |
Q03Z95 | NAGB_LEUMM | Glucosamine-6-phosphate isomerase | Leuconostoc | <M><N><I><I><R><V><K><D><V><E><Q><S><A><E><K><A><L><E><I><Y><Q><N><A><V><Q><H><G><A><K><V><L><G><L><A><T><G><S><T><P><I><P><L><Y><Q><K><L><A><T><S><Q><I><N><F><S><E><L><V><S><I><N><L><D><E><Y><L><G><L><D><G><E><D><E><Q><S><Y><R><Y><F><M><T><K><H><L><F><Q><Y><K><P><F><K><H><S><Y><V><P><D><G><K><S><E><D><H><E><A><A><I><K... | Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion.<BOP> | Q03Z95 |
Q9PAN6 | CCME_XYLFA | Heme chaperone CcmE | Xylella | <M><N><A><R><R><R><L><W><S><L><L><M><L><I><L><A><V><G><T><A><A><T><L><T><I><M><A><L><R><R><N><L><T><Y><L><Y><M><P><S><E><V><L><R><G><D><T><A><Q><Q><T><H><F><R><L><G><G><I><V><E><K><G><S><F><Q><R><T><S><G><T><L><H><T><R><F><I><V><T><D><G><N><A><R><L><Q><V><R><Y><A><R><I><L><P><D><L><F><R><E><G><Q><A><V><V><A><T><G><Q><M... | Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH.<BOP> | Q9PAN6 |
Q99NG9 | K199B_MOUSE | Keratin-associated protein 16-10b | Mus | <M><S><Y><Y><Y><G><N><Y><Y><G><G><L><G><Y><G><L><G><G><F><G><G><F><G><G><L><G><Y><G><Y><G><S><S><Y><G><L><G><G><Y><G><G><Y><G><Y><F><S><P><S><F><Y><G><G><Y><L><S><S><G><F><Y> | In the hair cortex, hair keratin intermediate filaments are embedded in an interfilamentous matrix, consisting of hair keratin-associated proteins (KRTAP), which are essential for the formation of a rigid and resistant hair shaft through their extensive disulfide bond cross-linking with abundant cysteine residues of ha... | Q99NG9 |
A4WEI4 | HLDE_ENT38 | D-glycero-beta-D-manno-heptose 1-phosphate adenylyltransferase | Enterobacter | <M><K><V><T><L><P><E><F><E><R><A><G><V><M><V><V><G><D><V><M><L><D><R><Y><W><Y><G><P><T><S><R><I><S><P><E><A><P><V><P><V><V><K><V><D><T><I><E><E><R><P><G><G><A><A><N><V><A><M><N><I><A><S><L><G><A><H><S><R><L><V><G><L><T><G><I><D><D><A><A><R><A><L><S><K><T><L><A><D><V><N><V><K><C><D><F><V><S><V><P><T><H><P><T><I><T><K><L... | Catalyzes the ADP transfer from ATP to D-glycero-beta-D-manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno-heptose.<BOP> | A4WEI4 |
A6TBU4 | GLPB_KLEP7 | Anaerobic glycerol-3-phosphate dehydrogenase subunit B | Klebsiella | <M><K><F><D><C><A><I><I><G><G><G><L><A><G><L><L><C><G><L><A><L><N><Q><H><G><L><R><S><V><I><I><S><R><G><Q><S><A><L><H><F><S><S><A><S><L><D><L><L><S><A><L><P><N><G><D><H><V><T><D><V><A><Q><G><L><Q><Q><L><A><E><Q><L><P><E><H><P><Y><S><R><L><G><A><E><A><V><L><K><Y><A><T><Q><T><E><A><L><L><A><A><C><G><A><V><M><Q><G><D><A><R... | Conversion of glycerol 3-phosphate to dihydroxyacetone. Uses fumarate or nitrate as electron acceptor.<BOP> | A6TBU4 |
Q9JJK3 | PEX3_CRILO | Peroxisomal assembly protein PEX3 | Cricetulus | <M><L><R><S><M><W><N><F><L><K><R><H><K><K><K><C><I><F><L><G><T><V><L><G><G><V><Y><I><L><G><K><Y><G><Q><K><K><I><R><E><I><Q><E><R><E><A><A><E><Y><I><A><Q><A><R><R><Q><Y><H><F><E><S><N><Q><R><T><C><N><M><T><V><L><S><M><L><P><T><L><R><E><A><L><M><Q><Q><L><N><S><E><S><L><T><A><L><L><K><N><R><P><S><N><K><L><E><I><W><E><D><L... | Involved in peroxisome biosynthesis and integrity. Assembles membrane vesicles before the matrix proteins are translocated. As a docking factor for PEX19, is necessary for the import of peroxisomal membrane proteins in the peroxisomes.<BOP> | Q9JJK3 |
B2XWK8 | NDHK_FAGEA | NADH-plastoquinone oxidoreductase subunit K | Fagopyrum | <M><N><S><V><E><F><L><P><L><D><R><I><T><P><N><S><V><I><S><T><T><S><N><D><L><S><N><W><S><R><L><S><S><L><W><P><L><L><Y><G><T><S><C><C><F><I><E><F><A><S><L><I><G><S><R><F><D><F><D><R><Y><G><L><V><P><R><S><S><P><R><Q><A><D><L><I><L><T><A><G><T><V><T><M><K><M><A><P><S><L><V><R><L><Y><E><Q><M><P><E><P><K><Y><V><I><A><M><G><A... | NDH shuttles electrons from NAD(P)H:plastoquinone, via FMN and iron-sulfur (Fe-S) centers, to quinones in the photosynthetic chain and possibly in a chloroplast respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translo... | B2XWK8 |
Q10588 | BST1_HUMAN | Cyclic ADP-ribose hydrolase 2 | Homo | <M><A><A><Q><G><C><A><A><S><R><L><L><Q><L><L><L><Q><L><L><L><L><L><L><L><L><A><A><G><G><A><R><A><R><W><R><G><E><G><T><S><A><H><L><R><D><I><F><L><G><R><C><A><E><Y><R><A><L><L><S><P><E><Q><R><N><K><N><C><T><A><I><W><E><A><F><K><V><A><L><D><K><D><P><C><S><V><L><P><S><D><Y><D><L><F><I><N><L><S><R><H><S><I><P><R><D><K><S><L... | Catalyzes both the synthesis of cyclic ADP-beta-D-ribose (cADPR) from NAD(+), and its hydrolysis to ADP-D-ribose (ADPR) . Cyclic ADPR is known to serve as an endogenous second messenger that elicits calcium release from intracellular stores, and thus regulates the mobilization of intracellular calcium (Probable). May b... | Q10588 |
A3Q695 | MSHD_MYCSJ | Mycothiol synthase | unclassified Mycobacterium | <M><T><S><I><D><W><R><S><A><L><T><D><D><E><Q><G><S><I><R><D><I><V><A><A><A><T><R><H><D><G><V><A><P><V><G><D><Q><V><L><R><E><L><P><A><D><R><T><R><H><L><V><A><V><D><P><D><A><G><A><V><V><G><Y><L><N><L><A><P><A><S><D><T><A><P><P><M><A><E><L><V><V><H><P><D><F><R><R><R><G><T><G><A><A><M><A><R><A><G><L><A><E><G><G><T><H><A><R... | Catalyzes the transfer of acetyl from acetyl-CoA to desacetylmycothiol (Cys-GlcN-Ins) to form mycothiol.<BOP> | A3Q695 |
P22549 | IPDE_DICDI | Cyclic nucleotide phosphodiesterase inhibitor | Dictyostelium | <M><A><K><I><I><I><S><L><I><L><L><L><S><L><F><S><F><S><Y><G><A><Y><N><C><N><K><L><N><C><S><S><K><N><T><K><C><R><T><F><S><C><T><S><V><V><G><C><Y><Y><T><D><K><C><T><S><P><D><L><C><H><N><S><A><C><N><A><S><T><G><N><C><T><L><T><T><I><S><C><N><D><N><N><P><C><T><D><D><F><C><H><P><G><Y><G><C><Y><S><V><P><N><S><C><D><P><G><V><I... | PDI acts by binding stoichiometrically to cyclic nucleotide phosphodiesterase, changing the KM of the enzyme for cAMP from 10 uM to 2 mM.<BOP> | P22549 |
P25269 | TRBP2_ARATH | Tryptophan synthase beta chain 2, chloroplastic | Arabidopsis | <M><A><T><A><S><T><A><A><T><F><R><P><S><S><V><S><A><S><S><E><L><T><H><L><R><S><P><S><K><L><P><K><F><T><P><L><P><S><A><R><S><R><S><S><S><S><F><S><V><S><C><T><I><A><K><D><P><A><V><V><M><A><D><S><E><K><I><K><A><A><G><S><D><P><T><M><W><Q><R><P><D><S><F><G><R><F><G><K><F><G><G><K><Y><V><P><E><T><L><M><H><A><L><S><E><L><E><T... | The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.<BOP> | P25269 |
P12706 | INS1_XENLA | Insulin-1 A chain | Xenopus | <M><A><L><W><M><Q><C><L><P><L><V><L><V><L><F><F><S><T><P><N><T><E><A><L><V><N><Q><H><L><C><G><S><H><L><V><E><A><L><Y><L><V><C><G><D><R><G><F><F><Y><Y><P><K><V><K><R><D><M><E><Q><A><L><V><S><G><P><Q><D><N><E><L><D><G><M><Q><L><Q><P><Q><E><Y><Q><K><M><K><R><G><I><V><E><Q><C><C><H><S><T><C><S><L><F><Q><L><E><S><Y><C><N> | Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.<BOP> | P12706 |
Q8CPW3 | NAGD_STAES | Acid sugar phosphatase | Staphylococcus | <M><K><H><Y><Q><A><Y><L><I><D><L><D><G><T><M><Y><K><G><T><D><E><I><D><G><A><A><Q><F><I><D><Y><L><N><N><N><H><I><P><H><L><Y><V><T><N><N><S><T><K><T><P><V><Q><V><T><E><K><L><R><E><M><H><I><D><A><K><P><D><E><V><V><T><S><A><L><A><T><A><D><Y><I><S><E><Q><H><P><N><A><T><V><Y><M><I><G><G><H><G><L><K><T><A><L><T><D><A><G><L><S... | Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro.<BOP> | Q8CPW3 |
Q2GG24 | GATB_EHRCR | Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit B | Ehrlichia | <M><T><I><I><K><G><N><R><C><D><W><E><V><V><I><G><L><E><V><H><A><Q><V><I><S><N><S><K><L><F><S><G><A><S><T><K><T><Y><D><A><L><P><N><T><Q><V><A><L><F><D><V><A><M><P><G><M><L><P><V><L><N><E><Y><C><V><Y><Q><A><I><K><T><G><I><A><L><S><C><K><I><N><K><Y><S><A><F><D><R><K><N><Y><F><Y><P><D><L><P><S><G><Y><Q><I><T><Q><F><Y><Y><P... | Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated ... | Q2GG24 |
F4JYE9 | DHFS_ARATH | Protein GLOBULAR ARREST 1 | Arabidopsis | <M><R><T><L><W><N><H><F><S><T><I><S><Y><I><K><I><S><P><R><M><R><R><I><S><A><A><N><L><I><S><N><R><N><L><S><T><I><S><S><T><E><D><P><E><L><R><D><F><V><G><F><L><E><S><L><K><N><Y><E><K><S><G><V><P><K><G><A><G><T><D><S><D><D><G><F><D><L><G><R><M><K><R><L><M><L><R><L><R><N><P><H><Y><K><Y><K><V><V><H><V><A><G><T><K><G><K><G><S... | Conversion of folates to polyglutamate derivatives, including tetrahydrofolate . Required during embryogenesis; from maternal tissues until the globular stage, and from the embryo after the globular stage .<BOP> | F4JYE9 |
B4RZN1 | RS10_ALTMD | 30S ribosomal protein S10 | Alteromonas | <M><P><N><Q><R><I><R><I><R><L><K><A><F><D><H><K><L><I><D><Q><S><T><A><E><I><V><E><T><A><K><R><T><G><A><Q><V><S><G><P><I><P><L><P><T><R><K><E><R><Y><T><V><L><I><S><P><H><V><N><K><D><A><R><D><Q><Y><E><I><R><T><H><K><R><L><V><D><I><I><E><P><T><D><K><T><V><D><A><L><M><R><L><D><L><A><A><G><V><D><V><Q><I><S><L><G> | Involved in the binding of tRNA to the ribosomes.<BOP> | B4RZN1 |
Q9I2H6 | RIMJ_PSEAE | [Ribosomal protein S5]-alanine N-acetyltransferase | Pseudomonas | <M><P><G><N><R><R><Q><V><P><I><L><H><R><D><A><D><F><L><L><R><A><L><Q><P><D><D><F><V><R><T><S><R><Y><E><N><A><N><R><E><H><L><A><P><W><E><P><L><R><D><P><G><Y><F><S><V><D><N><A><R><A><R><T><L><L><Q><V><A><S><M><D><E><G><E><A><L><L><L><L><L><L><D><P><D><D><G><E><V><L><G><R><C><S><Y><T><N><I><V><R><G><V><F><Q><A><C><H><L><G... | Acetylates the N-terminal alanine of ribosomal protein S5.<BOP> | Q9I2H6 |
B0JU07 | RIMM_MICAN | Ribosome maturation factor RimM | Microcystis | <M><E><E><N><W><L><E><I><G><T><I><V><A><P><Q><G><L><E><G><E><L><R><V><L><S><V><S><D><F><P><E><R><F><Q><K><R><G><M><R><G><I><Q><G><P><Q><G><G><E><I><R><E><I><T><L><L><R><G><R><E><L><P><G><K><N><V><Y><V><I><K><L><E><G><V><E><N><R><E><Q><A><E><A><L><R><G><Y><K><L><W><A><N><K><L><E><K><P><R><L><K><A><D><E><Y><H><V><S><E><L... | An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosoma... | B0JU07 |
Q18FC0 | RF1_HALWD | Translation termination factor aRF1 | Haloquadratum | <M><S><T><D><A><E><D><V><S><N><D><R><R><K><Y><E><F><R><K><V><I><E><E><L><R><E><Y><E><G><S><G><T><Q><L><V><T><I><Y><I><P><P><D><R><Q><V><S><D><V><V><A><H><I><T><Q><E><H><S><E><A><S><N><I><K><S><K><Q><T><R><T><N><V><Q><D><A><L><T><S><I><K><D><R><L><R><Y><Y><D><T><Y><P><P><D><N><G><I><V><L><F><S><G><A><V><S><T><G><G><G><Q... | Directs the termination of nascent peptide synthesis (translation) in response to the termination codons UAA, UAG and UGA.<BOP> | Q18FC0 |
Q49ZE3 | RS11_STAS1 | 30S ribosomal protein S11 | Staphylococcus | <M><A><R><K><Q><V><S><R><K><R><R><V><K><K><N><I><E><N><G><V><A><H><I><R><S><T><F><N><N><T><I><V><T><I><T><D><E><F><G><N><A><L><S><W><S><S><A><G><A><L><G><F><K><G><S><K><K><S><T><P><F><A><A><Q><M><A><S><E><T><A><S><K><T><A><M><E><H><G><L><K><S><V><E><V><T><V><K><G><P><G><P><G><R><E><S><A><I><R><A><L><Q><S><A><G><L><E><V... | Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome.<BOP> | Q49ZE3 |
Q57JR8 | DSBI_SALCH | Protein-disulfide oxidoreductase DsbI | Salmonella | <M><D><F><I><K><G><L><W><R><D><L><R><A><R><P><V><D><T><L><V><R><W><Q><E><Q><R><F><L><W><L><L><M><A><I><A><M><G><G><L><I><I><L><A><H><S><F><F><Q><I><Y><L><Y><M><A><P><C><E><Q><C><V><Y><I><R><Y><A><M><F><V><M><V><I><G><G><V><I><A><A><I><N><P><K><N><I><V><L><K><L><I><G><C><I><A><A><F><Y><G><S><I><M><G><I><K><F><S><I><K><L... | Required for disulfide bond formation in some proteins. Part of a redox system composed of DsbI and DsbL that mediates formation of an essential disulfide bond in AssT.<BOP> | Q57JR8 |
B8ZSB7 | RL23_MYCLB | 50S ribosomal protein L23 | Mycobacterium | <M><A><T><I><A><D><S><R><D><I><I><L><A><P><V><I><S><E><K><S><Y><G><L><L><D><D><N><V><Y><T><F><V><V><H><P><D><S><N><K><T><Q><I><K><I><A><I><E><K><I><F><S><V><K><V><A><S><V><N><T><S><N><R><K><G><K><C><K><R><T><R><T><G><F><G><R><R><K><N><T><K><R><A><I><V><T><L><A><P><G><S><K><S><I><D><L><F><G><T><P><A> | One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome.<BOP> | B8ZSB7 |
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