accession
stringlengths
6
10
name
stringlengths
6
11
Full Name
stringlengths
1
147
taxon
stringlengths
3
46
sequence
stringlengths
48
2.3k
function
stringlengths
11
1.34k
AlphaFoldDB
stringlengths
6
10
Q8NW49
THII_STAAW
tRNA 4-thiouridine synthase
Staphylococcus
<M><K><Y><D><H><L><L><V><R><Y><G><E><L><T><L><K><G><S><N><R><K><K><F><V><N><Q><L><R><N><N><V><N><K><S><L><K><G><L><D><G><F><V><V><K><G><K><R><D><R><M><Y><I><E><L><E><D><H><A><D><I><N><E><I><T><Y><R><L><S><K><I><F><G><I><K><S><I><S><P><V><L><K><V><E><K><T><I><E><A><M><S><A><A><A><I><K><F><A><Q><Q><F><E><E><N><S><T><F><K...
Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynt...
Q8NW49
Q14I27
Y810_FRAT1
Nucleoid-associated protein FTF0810c
Francisella
<M><N><F><D><M><S><K><L><M><Q><Q><A><Q><K><M><Q><E><Q><M><K><K><A><Q><Q><E><R><E><N><M><E><V><I><G><E><S><G><A><G><L><V><T><V><T><M><T><G><K><Y><D><V><K><S><V><S><I><D><N><S><L><M><S><E><D><K><E><I><L><E><D><L><I><A><A><A><V><N><S><A><V><K><K><V><E><E><N><S><T><A><S><S><D><I><Y><K><M><A><K><D><A><G><I><D><L><P><S><G><I...
Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection.<BOP>
Q14I27
Q5HPZ5
LSPA_STAEQ
Signal peptidase II
Staphylococcus
<M><K><K><K><Y><Y><I><S><I><S><L><L><M><T><F><I><V><L><V><F><D><Q><V><S><K><W><L><I><T><I><S><M><K><V><G><D><S><Y><E><I><I><P><N><F><L><N><I><T><S><H><R><N><N><G><A><A><W><G><I><L><S><G><K><M><L><F><F><Y><I><I><T><I><I><I><L><I><V><L><V><I><F><Y><I><K><E><A><Q><F><N><L><F><M><Q><V><A><I><S><L><L><F><A><G><A><L><G><N><F...
This protein specifically catalyzes the removal of signal peptides from prolipoproteins.<BOP>
Q5HPZ5
Q4FLS2
SSRP_PELUB
Small protein B
Candidatus Pelagibacter
<M><N><K><K><A><N><P><G><L><K><I><I><C><L><N><R><K><A><S><F><N><F><F><F><E><D><L><I><E><A><G><I><V><L><K><G><S><E><I><K><S><I><R><D><G><K><V><N><I><A><D><S><Y><A><V><E><K><D><G><E><I><V><L><I><N><S><H><I><A><A><F><K><Q><A><S><Y><S><N><H><N><P><T><D><E><R><K><L><L><L><N><K><K><E><I><N><K><L><I><G><K><M><Q><R><D><G><F><T...
Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemb...
Q4FLS2
B2U233
DNAJ_SHIB3
Chaperone protein DnaJ
Shigella
<M><A><K><Q><D><Y><Y><E><I><L><G><V><S><K><T><A><E><E><R><E><I><K><K><A><Y><K><R><L><A><M><K><Y><H><P><D><R><N><Q><G><D><K><E><A><E><A><K><F><K><E><I><K><E><A><Y><E><V><L><T><D><S><Q><K><R><A><A><Y><D><Q><Y><G><H><A><A><F><E><Q><G><G><M><G><G><G><G><F><G><G><G><A><D><F><S><D><I><F><G><D><V><F><G><D><I><F><G><G><G><R><G...
Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bou...
B2U233
Q3M546
MTND_TRIV2
Acireductone dioxygenase (Ni(2+)-requiring)
Trichormus
<M><A><T><L><L><L><E><D><G><T><I><E><S><N><L><D><E><I><A><R><E><L><A><P><L><G><V><Y><I><K><H><Y><D><P><G><T><S><I><L><F><P><H><L><L><I><Q><D><A><L><T><D><K><E><K><C><H><I><V><D><L><H><N><S><V><F><E><F><I><Q><Q><E><N><G><Y><L><W><C><D><L><L><N><V><H><P><G><S><P><N><L><Q><T><L><I><A><T><Y><A><K><Y><H><T><H><T><A><P><E><A...
Catalyzes 2 different reactions between oxygen and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4-methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine...
Q3M546
Q1J990
MNMG_STRPB
Glucose-inhibited division protein A
Streptococcus
<M><T><H><E><F><T><E><S><Y><D><V><I><V><I><G><A><G><H><A><G><V><E><A><S><L><A><T><S><R><M><G><C><K><T><L><L><A><T><I><N><L><D><M><L><A><F><M><P><C><N><P><S><I><G><G><S><A><K><G><I><V><V><R><E><I><D><A><L><G><G><E><M><G><K><N><I><D><K><T><Y><I><Q><M><K><M><L><N><T><G><K><G><P><A><V><R><A><L><R><A><Q><A><D><K><S><L><Y><A...
NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.<BOP>
Q1J990
B2G7Q2
THIM_LIMRJ
4-methyl-5-beta-hydroxyethylthiazole kinase
Limosilactobacillus
<M><V><Q><R><Q><I><N><W><S><L><I><D><R><V><R><A><K><N><P><I><V><L><N><L><A><N><L><V><T><I><D><K><V><A><D><A><V><S><A><V><G><A><S><P><I><M><S><V><E><P><A><E><A><D><E><M><V><M><L><A><N><A><L><S><I><N><L><G><T><I><N><E><H><Q><A><T><Q><I><R><T><V><L><R><A><A><T><P><L><K><P><L><V><L><D><P><V><A><V><S><A><V><P><S><R><L><K><F...
Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ).<BOP>
B2G7Q2
Q8ZVK6
AGOG_PYRAE
Pa-AGOG
Pyrobaculum
<M><A><A><E><S><Q><L><K><R><V><I><E><T><L><R><R><L><G><I><E><E><V><L><K><L><E><R><R><D><P><Q><Y><R><A><V><C><N><V><V><K><R><H><G><E><T><V><G><S><R><L><A><M><L><N><A><L><I><S><Y><R><L><T><G><K><G><E><E><H><W><E><Y><F><G><K><Y><F><S><Q><L><E><V><I><D><L><C><R><D><F><L><K><Y><I><E><T><S><P><F><L><K><I><G><V><E><A><R><K><K...
DNA repair enzyme that is part of the base excision repair (BER) pathway; protects from oxidative damage by removing the major product of DNA oxidation, 8-oxoguanine (GO), from single- and double-stranded DNA substrates.<BOP>
Q8ZVK6
Q9KUX4
CYSJ_VIBCH
Sulfite reductase [NADPH] flavoprotein alpha-component
Vibrio
<M><N><R><E><V><V><T><M><S><T><G><N><T><L><P><P><A><L><A><A><L><A><S><P><L><N><D><A><Q><L><N><Q><L><Q><Q><T><V><T><Q><L><N><A><Q><Q><L><A><W><V><S><G><Y><F><W><G><L><S><Q><S><N><A><L><S><V><P><H><I><S><A><G><Q><T><A><S><A><A><S><G><K><L><T><I><I><F><A><S><Q><T><G><N><A><K><G><V><A><Q><A><L><L><K><E><A><Q><A><A><G><I><Q...
Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L-cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH -> FAD -> FMN to the hemoprotein component.<BOP>
Q9KUX4
P68246
TNNI2_CHICK
Troponin I, fast-twitch isoform
Gallus
<M><S><D><E><E><K><K><R><R><A><A><T><A><R><R><Q><H><L><K><S><A><M><L><Q><L><A><V><T><E><I><E><K><E><A><A><A><K><E><V><E><K><Q><N><Y><L><A><E><H><C><P><P><L><S><L><P><G><S><M><Q><E><L><Q><E><L><C><K><K><L><H><A><K><I><D><S><V><D><E><E><R><Y><D><T><E><V><K><L><Q><K><T><N><K><E><L><E><D><L><S><Q><K><L><F><D><L><R><G><K><F...
Troponin I is the inhibitory subunit of troponin, the thin filament regulatory complex which confers calcium-sensitivity to striated muscle actomyosin ATPase activity.<BOP>
P68246
Q801R4
CTL2A_XENLA
CTD small phosphatase-like protein 2-A
Xenopus
<M><R><L><R><M><R><K><G><S><P><R><S><S><H><V><A><A><V><R><T><A><R><C><K><R><K><H><S><E><E><D><E><E><E><E><S><P><L><I><E><E><D><K><L><P><K><Q><E><T><G><L><L><S><T><I><K><N><F><I><K><G><S><T><N><K><E><D><R><E><N><P><A><K><R><S><K><V><E><R><D><L><D><N><N><L><I><T><S><T><P><R><T><G><D><K><P><S><K><P><I><A><R><V><R><R><K><S...
Probable phosphatase.<BOP>
Q801R4
B9V973
MCP1A_MACPC
Macrocypin-1a
Macrolepiota
<M><G><F><E><D><G><F><Y><T><I><L><H><L><A><E><G><Q><H><P><N><S><K><I><P><G><G><M><Y><A><S><S><K><D><G><K><D><V><P><V><T><A><E><P><L><G><P><Q><S><K><I><R><W><W><I><A><R><D><P><Q><A><G><D><D><M><Y><T><I><T><E><F><R><I><D><N><S><I><P><G><Q><W><S><R><S><P><V><E><T><E><V><P><V><Y><L><Y><D><R><I><K><A><E><E><T><G><Y><T><C><A...
Inhibits papain and cysteine cathepsin endopeptidases, and also inhibits cathepsins B and H, which exhibit both exopeptidase and endopeptidase activities.<BOP>
B9V973
Q8SPU5
BPIA1_BOVIN
Palate lung and nasal epithelium clone protein
Bos
<M><F><H><I><G><S><L><V><V><L><C><G><L><L><A><P><T><T><A><L><L><E><A><L><P><T><P><L><G><Q><T><L><P><L><A><V><T><P><A><L><A><P><S><P><P><D><L><A><G><S><L><T><G><A><L><S><N><G><L><L><S><E><G><L><L><G><I><L><E><N><L><P><L><L><D><I><L><K><T><R><G><N><A><P><S><G><L><L><G><S><L><L><G><K><V><T><S><L><T><P><L><L><N><N><I><I><E...
Lipid-binding protein which shows high specificity for the surfactant phospholipid dipalmitoylphosphatidylcholine (DPPC). Plays a role in the innate immune responses of the upper airways. Reduces the surface tension in secretions from airway epithelia and inhibits the formation of biofilm by pathogenic Gram-negative ba...
Q8SPU5
Q5AB49
Y6200_CANAL
Probable pathogenesis-related protein CaO19.6200
Candida
<M><K><F><L><Q><S><F><P><V><I><L><A><V><F><S><F><A><A><N><L><V><S><S><K><L><V><Y><E><Y><E><T><K><Y><V><T><V><E><I><V><T><I><V><S><G><E><T><T><Y><T><T><E><R><L><E><T><N><G><P><T><S><T><T><T><T><I><V><I><P><S><S><K><P><S><S><P><E><S><K><P><K><S><D><S><Q><P><M><F><Q><S><P><S><P><V><Q><I><T><P><S><T><T><S><I><N><N><A><P><S...
Secreted protein that acts as a virulence factor during infections.<BOP>
Q5AB49
Q7F8T6
OMT17_ORYSJ
Caffeoyl-CoA 3-O-methyltransferase ROMT17
Oryza sativa
<M><S><M><A><C><T><K><V><W><R><S><T><M><Y><T><P><R><R><L><K><R><T><T><P><A><S><R><V><S><S><T><A><M><A><A><A><N><G><D><A><S><H><G><A><N><G><G><I><Q><I><Q><S><K><E><M><K><T><A><I><H><S><N><D><S><P><K><T><L><L><K><S><E><S><L><H><E><Y><M><L><N><T><M><V><Y><P><R><E><N><E><F><M><R><E><L><R><L><I><T><S><E><H><T><Y><G><F><M><S...
Catalyzes the stepwise methylation of tricetin to its 3'-mono- and 3',5'-dimethyl ethers. No 3',4',5'-trimethylated ester derivatives are produced. Can use caffeoyl CoA, 5-hydroxyferulic acid, luteolin, tricetin, quercetin, myrcetin and 7,8-dihydroxyflavone as substrates, but not naringenin, apigenin or kaempferol. The...
Q7F8T6
P0C916
RBL1A_ACIFR
Ribulose bisphosphate carboxylase large chain 1
Acidithiobacillus
<M><A><V><K><T><Y><E><A><G><V><K><D><Y><R><Q><T><Y><W><A><P><E><Y><V><P><L><D><S><D><I><L><A><C><F><K><I><T><P><Q><P><G><V><D><R><E><E><A><A><A><A><V><A><A><E><S><S><T><G><T><W><T><T><V><W><T><D><L><L><T><D><M><D><Y><Y><K><G><R><A><Y><R><I><E><D><V><P><G><D><D><T><C><F><Y><A><F><V><A><Y><P><I><D><L><F><E><E><G><S><V><V...
RuBisCO catalyzes two reactions: the carboxylation of D-ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate. Both reactions occur simultaneously and in competition at the same active site.<BOP>
P0C916
Q9ZVT7
RRP4_ARATH
Ribosomal RNA-processing protein 4
Arabidopsis
<M><V><M><R><K><L><Q><L><P><L><S><Q><T><Q><K><V><R><F><E><R><A><I><E><R><L><Q><S><L><S><S><S><A><N><S><D><A><S><V><I><V><T><D><S><I><P><V><N><H><D><D><A><F><L><K><G><H><G><T><S><E><V><D><G><E><L><L><A><T><V><C><G><V><V><E><R><V><D><K><L><V><Y><V><R><T><L><R><A><R><Y><K><P><E><V><G><D><I><V><V><G><R><V><I><E><V><A><Q><K...
Non-catalytic component of the RNA exosome complex which has 3'->5' exoribonuclease activity and participates in a multitude of cellular RNA processing, maturation and degradation events. In vitro, is an active and distributive 3'->5' exonuclease requiring a free 3'-OH on the substrate and releasing nucleoside 5'-monop...
Q9ZVT7
A1QZN3
SYDND_BORT9
Non-discriminating aspartyl-tRNA synthetase
Borrelia
<M><F><K><T><I><K><C><N><Q><I><N><D><K><L><I><N><Q><K><I><E><I><N><A><W><V><K><K><I><R><H><H><G><K><V><T><F><I><N><L><R><D><R><Y><D><E><A><Q><V><L><V><N><D><E><K><L><L><K><I><T><S><Q><I><K><M><E><Y><C><I><K><V><Q><G><K><L><E><L><R><P><S><N><L><V><N><K><E><M><R><T><G><A><F><E><I><L><A><E><N><I><N><I><I><S><R><C><N><E><L...
Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn).<BOP>
A1QZN3
Q12TB6
TUSA_SHEDO
Sulfur carrier protein TusA
Shewanella
<M><T><D><V><F><S><Q><A><Q><H><Q><L><D><A><L><G><L><R><C><P><E><P><V><M><M><V><R><K><T><V><R><K><M><A><D><G><E><T><L><L><I><I><A><D><D><P><A><T><T><R><D><I><P><S><F><C><E><F><M><D><H><T><L><I><A><S><D><T><S><K><T><P><Y><Q><Y><L><L><K><K><G><R>
Sulfur carrier protein which probably makes part of a sulfur-relay system.<BOP>
Q12TB6
Q9X4Q2
METK_STRST
Methionine adenosyltransferase
Streptomyces
<M><S><R><R><L><F><T><S><E><S><V><T><E><G><H><P><D><K><I><A><D><Q><I><S><D><T><I><L><D><A><L><L><R><E><D><P><T><S><R><V><A><V><E><T><L><I><T><T><G><L><V><H><V><A><G><E><V><T><T><K><A><Y><A><P><I><A><Q><L><V><R><E><K><I><L><E><I><G><Y><D><S><S><K><K><G><F><D><G><A><S><C><G><V><S><V><S><I><G><A><Q><S><P><D><I><A><Q><G><V...
Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.<BOP>
Q9X4Q2
O74448
PIN1_SCHPO
Peptidyl-prolyl cis-trans isomerase pin1
Schizosaccharomyces
<M><S><N><T><G><L><P><K><P><W><I><V><K><I><S><R><S><R><N><R><P><Y><F><F><N><T><E><T><H><E><S><L><W><E><P><P><A><A><T><D><M><A><A><L><K><K><F><I><A><N><E><L><Q><E><S><V><T><P><T><E><A><S><N><S><P><K><I><R><A><S><H><L><L><V><K><H><R><E><S><R><R><P><S><S><W><K><E><E><H><I><T><R><S><K><E><E><A><R><K><L><A><E><H><Y><E><Q><L...
Has a role in the G1/S stage transition of mitosis where it is involved in the dephosphorylation of cdc25 and wee1.<BOP>
O74448
Q00604
NDP_HUMAN
X-linked exudative vitreoretinopathy 2 protein
Homo
<M><R><K><H><V><L><A><A><S><F><S><M><L><S><L><L><V><I><M><G><D><T><D><S><K><T><D><S><S><F><I><M><D><S><D><P><R><R><C><M><R><H><H><Y><V><D><S><I><S><H><P><L><Y><K><C><S><S><K><M><V><L><L><A><R><C><E><G><H><C><S><Q><A><S><R><S><E><P><L><V><S><F><S><T><V><L><K><Q><P><F><R><S><S><C><H><C><C><R><P><Q><T><S><K><L><K><A><L><R...
Activates the canonical Wnt signaling pathway through FZD4 and LRP5 coreceptor. Plays a central role in retinal vascularization by acting as a ligand for FZD4 that signals via stabilizing beta-catenin (CTNNB1) and activating LEF/TCF-mediated transcriptional programs. Acts in concert with TSPAN12 to activate FZD4 indepe...
Q00604
Q11HL3
LFTR_CHESB
Phenyalanyltransferase
unclassified Chelativorans
<M><T><R><P><L><A><P><G><F><H><I><P><P><D><L><L><L><R><A><Y><A><T><G><V><F><P><M><A><E><H><A><D><D><P><E><V><F><W><V><R><P><E><M><R><G><I><I><P><L><D><K><F><H><V><P><K><S><L><R><K><L><L><R><R><Q><P><Y><E><V><R><Y><D><T><D><F><T><G><V><I><D><A><C><A><E><P><S><A><E><R><A><E><T><W><I><N><E><P><I><R><V><A><Y><T><E><L><F><K...
Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine.<BOP>
Q11HL3
Q15YN6
RL2_PSEA6
50S ribosomal protein L2
Pseudoalteromonas
<M><P><L><L><K><A><K><P><T><S><A><G><R><R><H><V><V><Q><V><V><N><P><D><L><H><K><G><A><P><Y><A><P><L><L><E><K><N><S><K><S><G><G><R><N><N><N><G><R><I><T><V><R><H><V><G><G><G><H><K><Q><H><Y><R><V><I><D><F><K><R><N><K><D><G><I><P><A><K><I><E><R><L><E><Y><D><P><N><R><S><A><N><I><C><L><V><L><Y><A><D><G><E><R><R><Y><I><L><A><P...
One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.<...
Q15YN6
Q7V6I0
PSBD_PROMM
Photosystem Q(A) protein
Prochlorococcus
<M><T><I><A><V><G><R><A><P><Q><R><G><W><F><D><V><L><D><D><W><L><K><R><D><R><F><V><F><V><G><W><S><G><L><L><L><F><P><T><A><Y><L><A><L><G><G><W><F><T><G><T><T><F><V><T><S><W><Y><T><H><G><I><A><S><S><Y><L><E><G><C><N><F><L><S><A><A><V><S><T><P><A><D><A><M><G><H><S><L><L><L><L><W><G><P><E><A><Q><G><D><F><V><R><W><C><Q><L><G...
Photosystem II (PSII) is a light-driven water:plastoquinone oxidoreductase that uses light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation. It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photoni...
Q7V6I0
P51984
CREB_HYDVD
cAMP response element-binding protein
Hydra
<M><E><L><A><R><H><S><F><Q><Q><P><L><N><V><A><P><S><L><S><N><V><V><N><K><T><S><V><V><L><Q><Q><Q><S><V><I><Q><P><N><Q><H><Q><L><Q><H><Q><L><Q><T><M><H><D><G><G><I><D><G><K><R><R><E><I><L><A><R><R><P><S><Y><R><R><I><L><D><D><L><A><G><D><G><P><V><K><M><E><N><Y><D><D><T><G><S><S><G><E><S><S><P><N><G><N><N><E><E><D><I><N><G...
This protein binds the cAMP response element (CRE), sequence present in many viral and cellular promoters. Could regulate the transcriptional activity of genes involved in regeneration processes.<BOP>
P51984
Q20303
ELO6_CAEEL
Monomethyl branched-chain fatty acid elongase 6
Caenorhabditis
<M><P><Q><G><E><V><S><F><F><E><V><L><T><T><A><P><F><S><H><E><L><S><K><K><H><I><A><Q><T><Q><Y><A><A><F><W><I><S><M><A><Y><V><V><V><I><F><G><L><K><A><V><M><T><N><R><K><P><F><D><L><T><G><P><L><N><L><W><N><A><G><L><A><I><F><S><T><L><G><S><L><A><T><T><F><G><L><L><H><E><F><F><S><R><G><F><F><E><S><Y><I><H><I><G><D><F><Y><N><G...
Catalyzes the first and rate-limiting reaction of the four reactions that constitute the long-chain fatty acids elongation cycle. Uses malonyl-CoA to add 2 carbons per cycle to the chain of long-chain fatty acids. Condensing enzyme required for the formation of isoheptadecanoate (C17iso), which plays critical roles in ...
Q20303
Q9BZI7
REN3B_HUMAN
Up-frameshift suppressor 3 homolog on chromosome X
Homo
<M><K><E><E><K><E><H><R><P><K><E><K><R><V><T><L><L><T><P><A><G><A><T><G><S><G><G><G><T><S><G><D><S><S><K><G><E><D><K><Q><D><R><N><K><E><K><K><E><A><L><S><K><V><V><I><R><R><L><P><P><T><L><T><K><E><Q><L><Q><E><H><L><Q><P><M><P><E><H><D><Y><F><E><F><F><S><N><D><T><S><L><Y><P><H><M><Y><A><R><A><Y><I><N><F><K><N><Q><E><D><I...
Involved in nonsense-mediated decay (NMD) of mRNAs containing premature stop codons by associating with the nuclear exon junction complex (EJC) and serving as link between the EJC core and NMD machinery. Recruits UPF2 at the cytoplasmic side of the nuclear envelope and the subsequent formation of an UPF1-UPF2-UPF3 surv...
Q9BZI7
A1ALL5
ATPA_PELPD
F-ATPase subunit alpha
Pelobacter
<M><K><I><R><A><E><E><I><S><E><I><I><K><K><Q><I><R><E><Y><G><K><E><V><E><V><S><E><T><G><T><I><I><S><I><G><D><G><I><A><R><I><H><G><L><S><G><A><M><A><G><E><L><L><E><F><P><G><G><V><S><G><M><V><L><N><L><E><E><D><N><V><G><A><A><V><L><G><E><F><T><A><I><K><E><G><H><T><V><K><R><T><G><R><I><A><E><V><P><V><G><E><A><L><I><G><R><V...
Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit.<BOP>
A1ALL5
Q5F605
PYRD_NEIG1
Dihydroorotate oxidase
Neisseria
<M><Y><P><L><A><R><R><I><L><F><A><L><D><A><E><K><A><H><H><F><T><L><D><A><L><N><T><V><Y><K><L><G><L><I><P><V><T><D><N><R><T><K><P><I><K><L><M><G><M><D><L><P><N><P><V><G><L><A><A><G><L><D><K><N><G><E><Y><I><D><A><L><G><A><L><G><F><G><F><L><E><I><G><T><V><T><R><N><P><Q><P><G><N><P><Q><P><R><L><F><R><V><P><E><H><Q><G><I><I...
Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor.<BOP>
Q5F605
D4GTK4
SECF_HALVD
Protein-export membrane protein SecF
Haloferax
<M><V><E><F><T><V><P><E><V><D><Y><T><R><Y><T><N><R><Q><L><A><A><V><P><L><A><V><L><A><V><A><L><L><V><I><G><G><W><Y><V><A><T><G><A><P><V><N><P><G><V><D><F><T><G><G><T><E><L><R><I><A><T><D><A><P><Q><S><E><V><A><A><A><F><D><S><Q><P><E><S><I><R><S><V><A><A><D><G><T><Y><V><V><T><F><Q><S><G><S><A><T><S><T><E><L><Q><T><Q><A><E...
Involved in protein export.<BOP>
D4GTK4
B2IH44
CTAA_BEII9
Cytochrome aa3-controlling protein
Beijerinckia
<M><S><A><L><D><T><A><P><A><G><S><L><A><E><T><H><A><Q><R><G><T><R><A><V><A><F><W><L><W><S><L><A><V><L><V><F><L><M><V><V><L><G><G><A><T><R><L><T><E><S><G><L><S><I><T><E><W><K><P><I><S><G><A><L><P><P><L><S><A><E><A><W><Q><A><E><F><E><N><Y><K><R><I><P><Q><Y><A><A><L><F><P><D><M><D><L><A><G><F><K><F><I><F><F><F><E><W><S><H...
Catalyzes the conversion of heme O to heme A by two successive hydroxylations of the methyl group at C8. The first hydroxylation forms heme I, the second hydroxylation results in an unstable dihydroxymethyl group, which spontaneously dehydrates, resulting in the formyl group of heme A.<BOP>
B2IH44
B7NSJ1
NORW_ECO7I
Flavorubredoxin reductase
Escherichia
<M><S><N><S><I><V><I><I><G><S><G><F><A><A><R><Q><L><V><K><N><I><R><K><Q><D><A><S><I><P><L><T><L><I><A><A><D><S><M><D><E><Y><N><K><P><D><L><S><H><V><I><S><Q><G><Q><R><A><D><D><L><T><R><Q><T><A><G><E><F><A><E><Q><F><N><L><R><L><F><P><H><T><W><V><T><D><I><D><A><E><A><H><V><V><K><S><Q><N><N><Q><W><Q><Y><D><K><L><V><L><A><T...
One of at least two accessory proteins for anaerobic nitric oxide (NO) reductase. Reduces the rubredoxin moiety of NO reductase.<BOP>
B7NSJ1
A4R5F6
ARGJ_MAGO7
Arginine biosynthesis bifunctional protein ArgJ beta chain
Pyricularia
<M><A><S><K><S><T><S><T><A><V><W><G><Q><L><R><H><L><A><Q><Q><Q><T><R><C><Y><S><A><T><A><D><S><I><P><A><S><K><K><K><Y><V><P><T><K><G><V><Y><P><K><G><F><R><V><S><G><T><I><V><G><V><K><P><G><N><T><T><K><P><D><L><A><F><V><T><S><D><T><P><C><A><A><A><A><V><F><T><K><N><R><F><Q><A><A><P><V><T><F><S><R><D><L><L><K><K><K><G><N><S...
Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of acetylglutamate from glutamate and acetyl-CoA, and of ornithine by transacetylation between acetylornithine and glutamate.<BOP>
A4R5F6
Q8J1Z1
TIM9_NEUCR
Mitochondrial import inner membrane translocase subunit tim9
Neurospora
<M><D><G><L><T><A><A><E><S><R><E><L><D><Q><R><L><Q><K><R><Q><V><K><E><F><M><S><V><F><G><N><L><V><D><N><C><F><T><A><C><V><D><D><F><T><S><K><A><L><S><G><R><E><S><G><C><I><S><R><C><V><L><K><S><M><S><T><Q><T><R><L><G><E><R><F><G><E><L><N><A><A><M><T><A><E><M><Q><R><R>
Mitochondrial intermembrane chaperone that participates in the import and insertion of multi-pass transmembrane proteins into the mitochondrial inner membrane. Also required for the transfer of beta-barrel precursors from the TOM complex to the sorting and assembly machinery (SAM complex) of the outer membrane. Acts as...
Q8J1Z1
Q87YR0
FOLD1_PSESM
Methenyltetrahydrofolate cyclohydrolase
Pseudomonas
<M><T><A><K><L><I><D><G><K><A><I><A><A><S><L><R><Q><Q><I><A><K><R><V><A><E><R><S><Q><Q><G><L><R><T><P><G><L><A><V><I><L><V><G><S><D><P><A><S><Q><V><Y><V><S><H><K><R><K><D><C><E><E><V><G><F><I><S><Q><A><Y><D><L><P><A><E><T><T><Q><V><A><L><T><N><L><I><D><R><L><N><E><D><A><A><V><D><G><I><L><L><Q><L><P><L><P><A><H><L><D><A...
Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.<BOP>
Q87YR0
O30394
TYSY_BACAT
Thymidylate synthase A
Bacillus
<S><E><V><P><I><L><T><T><K><K><L><A><W><K><T><A><I><K><E><L><L><W><I><W><Q><L><K><S><N><D><V><N><D><L><N><K><M><S><V><H><I><W><D><Q><W><K><Q><E><D><G><T><I><G><H><A><Y><G><F><Q><L><G><K><K><N><R><S><L><N><G><E><K><V><D><Q><V><D><Y><L><L><H><Q><L><K><N><N><P><S><S><R><R><H><I><T><M><L><W><N><P><D><E><L><D><A><M><A><L><T...
Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracell...
O30394
O95196
CSPG5_HUMAN
Neuroglycan C
Homo
<M><G><R><A><G><G><G><G><P><G><R><G><P><P><P><L><L><L><F><L><G><A><A><L><V><L><A><S><G><A><V><P><A><R><E><A><G><S><A><V><E><A><E><E><L><V><K><G><S><P><A><W><E><P><P><A><N><D><T><R><E><E><A><G><P><P><A><A><G><E><D><E><A><S><W><T><A><P><G><G><E><L><A><G><P><E><E><V><L><Q><E><S><A><A><V><T><G><T><A><W><L><E><A><D><S><P><G...
May function as a growth and differentiation factor involved in neuritogenesis. May induce ERBB3 activation.<BOP>
O95196
B5XNE5
MSRQ_KLEP3
Flavocytochrome MsrQ
Klebsiella
<M><R><F><T><V><K><Q><I><A><W><L><K><V><F><L><H><L><A><G><F><L><P><L><V><W><L><F><W><A><G><H><Q><G><Y><F><S><A><D><P><A><K><D><I><Q><H><F><T><G><R><M><A><L><K><F><L><L><A><T><L><L><V><A><P><L><A><R><Y><A><K><Q><P><L><L><I><R><I><R><R><L><L><G><L><W><C><F><A><W><A><T><L><H><L><T><S><Y><T><L><L><E><L><G><I><N><N><L><A><L...
Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essentia...
B5XNE5
Q2LR03
GREA_SYNAS
Transcript cleavage factor GreA
Syntrophus
<M><E><K><M><P><I><T><K><S><G><F><E><N><L><K><K><E><L><E><H><L><K><C><V><L><I><P><A><N><I><K><D><I><E><I><A><R><A><H><G><D><L><S><E><N><A><E><Y><T><A><A><K><E><K><Q><S><F><L><H><G><K><L><Q><E><L><E><N><N><L><A><L><S><N><V><I><D><L><K><M><L><S><D><D><R><I><V><F><G><A><T><V><I><I><E><E><A><S><T><G><K><Q><T><N><Y><Q><L><V...
Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factor...
Q2LR03
Q84TG3
PUB23_ARATH
U-box domain-containing protein 23
Arabidopsis
<M><S><G><G><I><M><D><E><E><I><E><I><P><P><F><F><L><C><P><I><S><L><E><I><M><K><D><P><V><I><V><S><T><G><I><T><Y><D><R><D><S><I><E><K><W><L><F><A><G><K><K><N><S><C><P><V><T><K><Q><D><I><T><D><A><D><L><T><P><N><H><T><L><R><R><L><I><Q><S><W><C><T><L><N><A><S><Y><G><V><E><R><I><P><T><P><R><P><P><I><C><K><S><E><I><E><K><L><I...
E3 ubiquitin-protein ligase that negatively regulates water stress response. May control in coordination with PUB23 a drought signaling pathway by ubiquitinating cytosolic RPN12a. Acts as negative regulator of the immunity triggered by the pathogen-associated molecular patterns (PAMPs), in association with PUB22 and PU...
Q84TG3
Q7M8E4
RL24_WOLSU
50S ribosomal protein L24
Wolinella
<M><V><K><F><Q><I><K><K><G><D><K><V><Q><V><I><A><G><D><D><K><G><K><V><A><E><V><I><K><V><M><P><K><S><S><Q><V><I><V><A><G><C><K><V><A><K><K><S><V><K><P><S><E><Q><N><P><K><G><G><F><V><N><K><E><M><P><I><H><I><S><N><V><K><K><V><E><A>
One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.<BOP>
Q7M8E4
Q0I5I2
FTSB_HAES1
Cell division protein FtsB
Histophilus
<M><R><L><F><I><L><S><L><F><A><L><L><V><M><F><Q><Y><D><F><W><F><G><K><N><G><Y><L><D><Y><Q><D><I><K><A><E><I><I><Q><R><K><Q><E><N><K><K><L><S><Q><R><N><Q><T><I><F><A><E><I><Q><D><L><K><N><G><I><E><A><I><E><E><R><A><R><M><E><H><E><M><I><K><Q><N><E><V><F><Y><R><I><V><K><N><K><N><R>
Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic.<BOP>
Q0I5I2
Q91ZB5
MRGRG_MOUSE
Evolutionary breakpoint transcript 2 protein
Mus
<M><F><S><I><F><N><I><W><G><T><F><N><K><V><L><F><F><L><S><L><T><V><S><L><A><G><L><V><G><N><A><L><L><L><W><H><L><G><L><H><I><K><K><G><P><F><N><T><Y><L><L><H><L><A><A><A><D><F><L><F><L><S><C><Q><V><G><F><S><I><A><T><I><V><S><G><H><E><D><T><L><Y><F><P><V><T><F><L><W><F><A><V><G><L><W><L><L><A><A><F><S><V><D><C><C><L><A><Y...
Orphan receptor. May regulate nociceptor function and/or development, including the sensation or modulation of pain.<BOP>
Q91ZB5
B8EAU2
THII_SHEB2
tRNA 4-thiouridine synthase
Shewanella
<M><K><F><I><V><K><L><Y><P><E><I><M><M><K><S><K><P><V><R><M><R><F><T><K><M><L><E><T><N><I><R><N><V><L><K><K><V><D><E><D><A><K><V><Q><R><Q><W><D><R><I><M><V><M><V><P><K><D><K><P><E><L><A><Q><A><F><G><E><R><L><A><C><I><P><G><I><A><H><V><V><Q><V><D><E><Y><S><F><E><S><V><D><D><I><Y><Q><Q><V><L><P><V><Y><R><D><Q><L><A><G><K...
Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynt...
B8EAU2
Q1D7Z0
ENGB_MYXXD
Probable GTP-binding protein EngB
Myxococcus
<M><I><K><V><L><D><A><R><F><V><T><T><A><V><E><P><K><G><Y><P><T><D><H><T><A><E><V><A><F><V><G><R><S><N><V><G><K><S><S><M><I><N><A><L><T><G><R><R><K><L><V><R><V><S><N><T><P><G><R><T><R><T><L><N><F><F><D><V><D><L><E><R><G><G><V><R><H><Q><I><R><L><A><D><L><P><G><Y><G><F><A><K><A><S><K><A><D><K><A><Q><W><E><K><M><I><T><T><Y...
Necessary for normal cell division and for the maintenance of normal septation.<BOP>
Q1D7Z0
Q5HJ89
ESSA_STAAC
ESAT-6 secretion machinery protein EssA
Staphylococcus
<M><L><M><N><S><V><I><A><L><T><F><L><T><A><S><S><N><N><G><G><L><N><I><D><V><Q><Q><E><E><E><K><R><I><N><N><D><L><N><Q><Y><D><T><T><L><F><N><K><D><S><K><A><V><N><D><A><I><A><K><Q><K><K><E><R><Q><Q><Q><I><K><N><D><M><F><Q><N><Q><A><S><H><S><T><R><L><N><E><T><K><K><V><L><F><S><K><S><N><L><E><K><T><S><E><S><D><K><S><P><Y><I...
Component of the ESAT-6 secretion system (Ess). Required for the secretion of EsxA and EsxB.<BOP>
Q5HJ89
Q8U9L5
PAL_AGRFC
Outer membrane lipoprotein Omp16 homolog
Agrobacterium tumefaciens complex
<M><S><R><T><N><I><S><A><L><S><P><M><Q><K><L><A><R><N><P><A><V><I><A><M><T><L><A><L><A><L><A><G><C><A><N><K><K><N><M><P><N><S><A><G><E><L><G><L><G><G><A><G><S><A><T><P><G><S><Q><Q><D><F><T><V><N><V><G><D><R><I><F><F><D><T><D><S><T><S><I><R><A><D><A><Q><Q><T><L><Q><R><Q><A><Q><W><L><S><R><Y><P><N><Y><A><I><T><V><E><G><H...
Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.<BOP>
Q8U9L5
Q9N2D1
TRYT_PIG
Tryptase
Sus
<M><L><N><L><L><V><L><A><L><P><L><L><V><S><L><V><H><T><A><P><A><P><G><Q><A><L><E><R><A><G><I><V><G><G><K><E><A><P><G><H><K><W><P><W><Q><V><S><L><R><C><L><D><Q><Y><W><K><H><F><C><G><G><S><L><I><H><P><Q><W><V><L><T><A><A><H><C><F><G><P><E><K><A><D><P><L><Y><I><R><V><Q><L><G><E><Q><H><L><Y><Y><Q><D><R><L><L><L><V><S><R><I...
Tryptase is the major neutral protease present in mast cells and is secreted upon the coupled activation-degranulation response of this cell type.<BOP>
Q9N2D1
Q53LQ0
PDI11_ORYSJ
Endosperm storage protein 2
Oryza sativa
<M><A><I><S><K><A><W><I><S><L><L><L><A><L><A><V><V><L><S><A><P><A><A><R><A><E><E><A><A><A><A><E><E><G><G><D><A><A><A><E><A><V><L><T><L><D><A><D><G><F><D><E><A><V><A><K><H><P><F><M><V><V><E><F><Y><A><P><W><C><G><H><C><K><K><L><A><P><E><Y><E><K><A><A><Q><E><L><S><K><H><D><P><P><I><V><L><A><K><V><D><A><N><D><E><K><N><K><P...
Probable protein disulfide isomerase that plays an essential role in the segregation of proglutelin and prolamin polypeptides within the ER lumen of endosperm. Required to retain proglutelin in the cisternal ER lumen until ER export and, thereby, indirectly prevents heterotypic interactions with prolamin polypeptides.<...
Q53LQ0
P24711
INVO_CEPBA
Involucrin
Cephalopachus
<M><S><Q><Q><Q><T><L><P><V><T><L><P><P><A><L><S><Q><E><L><L><K><T><V><P><P><P><A><N><T><Q><Q><D><Q><M><K><Q><P><T><P><S><P><A><P><C><Q><K><G><P><S><E><L><P><V><E><K><H><P><A><P><V><K><Q><V><P><E><Q><E><C><E><P><Q><Q><Q><D><H><Q><E><P><E><L><Q><L><G><R><K><Q><Q><E><P><Q><E><Q><E><V><H><P><G><K><Q><Q><Q><K><P><Q><E><Q><E...
Part of the insoluble cornified cell envelope (CE) of stratified squamous epithelia.<BOP>
P24711
P0DPK3
NT2NB_HUMAN
Notch homolog 2 N-terminal-like protein B
Homo
<M><P><A><L><R><P><A><L><L><W><A><L><L><A><L><W><L><C><C><A><T><P><A><H><A><L><Q><C><R><D><G><Y><E><P><C><V><N><E><G><M><C><V><T><Y><H><N><G><T><G><Y><C><K><C><P><E><G><F><L><G><E><Y><C><Q><H><R><D><P><C><E><K><N><R><C><Q><N><G><G><T><C><V><A><Q><A><M><L><G><K><A><T><C><R><C><A><S><G><F><T><G><E><D><C><Q><Y><S><T><S><H...
Human-specific protein that promotes neural progenitor proliferation and evolutionary expansion of the brain neocortex by regulating the Notch signaling pathway . Able to promote neural progenitor self-renewal, possibly by down-regulating neuronal differentiation genes, thereby delaying the differentiation of neuronal ...
P0DPK3
A7ZSB6
NANE_ECO24
ManNAc-6-P epimerase
Escherichia
<M><S><L><L><A><Q><L><D><Q><K><I><A><A><N><G><G><L><I><V><S><C><Q><P><V><P><D><S><P><L><D><K><P><E><I><V><A><A><M><A><L><A><A><E><Q><A><G><A><V><A><I><R><I><E><G><V><A><N><Q><Q><A><T><R><A><V><V><S><V><P><I><I><G><I><V><K><R><D><L><E><D><S><P><V><R><I><T><A><Y><I><E><D><V><D><A><L><A><Q><A><G><A><D><I><I><A><I><D><G><T...
Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P).<BOP>
A7ZSB6
P22458
VTNC_RABIT
Serum-spreading factor
Oryctolagus
<M><A><P><L><R><P><I><F><T><L><A><L><L><L><W><V><V><L><A><D><Q><E><S><C><K><D><R><C><T><E><G><F><N><A><N><R><K><C><Q><C><D><E><L><C><S><Y><Y><Q><S><C><C><A><D><Y><A><A><E><C><K><P><Q><V><T><R><G><D><V><F><T><M><P><E><D><E><Y><G><P><Y><D><Y><I><E><Q><T><K><D><N><A><S><V><H><A><Q><P><E><S><P><T><V><G><Q><E><P><T><L><S><P...
Vitronectin is a cell adhesion and spreading factor found in serum and tissues. Vitronectin interact with glycosaminoglycans and proteoglycans. Is recognized by certain members of the integrin family and serves as a cell-to-substrate adhesion molecule. Inhibitor of the membrane-damaging effect of the terminal cytolytic...
P22458
Q02020
FIBB_CHICK
Fibrinogen beta chain
Gallus
<A><S><V><E><Y><D><N><E><E><D><S><P><Q><I><D><A><R><A><H><R><P><L><D><K><R><Q><E><A><A><P><T><L><R><P><V><A><P><P><I><S><G><T><G><Y><Q><P><R><P><P><K><Q><D><K><Q><A><M><K><K><G><P><I><I><Y><P><D><A><G><G><C><K><H><P><L><D><E><L><G><V><L><C><P><T><G><C><E><L><Q><T><T><L><L><K><Q><E><K><T><V><K><P><V><L><R><D><L><K><D><R...
Cleaved by the protease thrombin to yield monomers which, together with fibrinogen alpha (FGA) and fibrinogen gamma (FGG), polymerize to form an insoluble fibrin matrix. Fibrin has a major function in hemostasis as one of the primary components of blood clots.<BOP>
Q02020
P78795
EIF3G_SCHPO
Translation initiation factor eIF3 p33 subunit homolog
Schizosaccharomyces
<M><S><S><S><K><S><L><D><W><A><D><D><E><D><Y><G><T><G><L><P><S><I><Q><T><F><D><N><P><D><G><T><K><T><M><I><E><F><R><I><D><D><N><G><K><K><V><K><V><T><R><V><I><R><K><T><V><I><T><E><R><V><Q><H><A><V><A><E><R><K><K><W><K><K><F><G><K><E><A><G><K><N><S><G><V><D><A><R><T><T><S><V><G><E><N><V><Q><L><R><L><Q><L><G><W><T><T><T><K...
RNA-binding component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and...
P78795
Q8IZ08
GP135_HUMAN
G-protein coupled receptor 135
Homo
<M><E><E><P><Q><P><P><R><P><P><A><S><M><A><L><L><G><S><Q><H><S><G><A><P><S><A><A><G><P><P><G><G><T><S><S><A><A><T><A><A><V><L><S><F><S><T><V><A><T><A><A><L><G><N><L><S><D><A><S><G><G><G><T><A><A><A><P><G><G><G><G><L><G><G><S><G><A><A><R><E><A><G><A><A><V><R><R><P><L><G><P><E><A><A><P><L><L><S><H><G><A><A><V><A><A><Q><A...
Orphan receptor. Has spontaneous activity for beta-arrestin recruitment . Shows a reciprocal regulatory interaction with the melatonin receptor MTNR1B most likely through receptor heteromerization .<BOP>
Q8IZ08
W3X7K0
PFMAD_PESFW
Conidial pigment biosynthesis cluster protein D
Pestalotiopsis
<M><W><T><A><R><L><S><S><I><A><V><L><T><Q><V><V><G><T><W><A><D><T><I><T><L><N><W><E><I><T><W><V><N><A><A><P><D><G><F><H><R><P><V><I><G><V><N><G><K><W><P><C><P><P><I><H><A><T><V><G><D><T><V><V><I><N><M><K><N><S><L><G><N><Q><T><T><G><L><H><F><H><G><I><N><Q><L><D><T><N><Y><M><D><G><A><S><M><V><N><S><C><P><V><V><P><G><S><S...
Multicopper oxidase; part of the gene cluster that mediates the biosynthesis of dihydroxynaphthalene (DHN)-melanin, a bluish-green pigment forming a dark layer in the conidial wall that protects the conidia from UV radiations . The first step of the pathway is the production of the pentaketide 1,3,6,8-tetrahydroxynapht...
W3X7K0
Q9PTQ7
DMRT1_CHICK
Doublesex- and mab-3-related transcription factor 1
Gallus
<M><P><G><D><S><P><V><V><S><K><R><A><A><P><K><P><R><R><A><A><M><P><G><D><S><P><V><V><S><K><P><P><D><G><A><G><P><G><D><K><A><G><G><L><G><K><A><A><A><Q><M><A><A><A><P><A><A><G><K><K><L><P><R><L><P><K><C><A><R><C><R><N><H><G><Y><S><S><P><L><K><G><H><K><R><F><C><M><W><R><D><C><Q><C><K><K><C><S><L><I><A><E><R><Q><R><V><M><A...
Transcription factor that plays a key role in male sex determination. Acts both as a transcription repressor and repressor.<BOP>
Q9PTQ7
A5VR03
RL2_BRUO2
50S ribosomal protein L2
Brucella
<M><A><L><K><H><F><N><P><I><T><P><G><Q><R><Q><L><V><I><V><D><R><S><E><L><Y><K><G><K><P><V><K><S><L><T><E><G><L><S><K><K><G><G><R><N><N><T><G><R><I><T><V><R><F><Q><G><G><G><H><K><R><S><Y><R><F><I><D><F><K><R><R><K><L><D><V><V><G><T><V><E><R><L><E><Y><D><P><N><R><T><A><F><I><A><L><I><R><Y><T><D><G><E><L><A><Y><I><L><A><P...
One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.<...
A5VR03
Q6MSP3
RL15_MYCMS
50S ribosomal protein L15
Mycoplasma
<M><K><L><N><E><L><K><Y><T><P><G><S><K><T><K><A><T><I><V><G><R><G><M><A><S><G><K><G><K><T><A><T><R><G><H><K><G><Q><N><S><R><S><G><G><G><V><R><P><G><F><E><G><G><Q><T><P><L><F><R><R><L><P><K><V><G><F><T><S><L><N><Q><K><Q><Y><T><I><L><N><L><S><D><L><E><T><L><G><L><E><K><I><D><H><E><S><L><I><N><S><K><I><I><K><N><N><A><S><L...
Binds to the 23S rRNA.<BOP>
Q6MSP3
Q21SF4
RL1_ALBFT
50S ribosomal protein L1
Rhodoferax
<M><T><Q><L><T><K><K><Q><K><S><F><Q><G><K><V><D><S><N><K><L><Y><P><L><A><D><A><L><G><L><V><K><E><C><A><T><A><K><F><D><E><S><I><D><V><A><V><Q><L><G><I><D><A><K><K><S><D><Q><V><V><R><G><A><V><V><L><P><N><G><T><G><K><T><K><R><V><A><V><F><A><Q><G><A><K><A><E><E><A><K><A><A><G><A><D><I><V><G><M><D><D><L><A><A><M><I><K><A><G...
Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.<BOP>
Q21SF4
Q39E95
NTPPA_BURL3
Nucleotide pyrophosphatase
Burkholderia cepacia complex
<M><P><S><S><T><P><P><A><L><F><P><T><L><Y><L><A><S><Q><S><P><R><R><Q><E><L><L><Q><Q><I><G><V><R><F><E><L><L><L><P><R><P><D><E><D><A><E><A><L><E><A><E><L><P><G><E><A><A><D><A><Y><V><R><R><V><T><I><A><K><A><E><A><A><R><A><R><L><V><A><S><G><K><P><A><S><P><V><L><V><A><D><T><T><V><T><I><D><G><A><I><L><G><K><P><A><N><A><D><D...
Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.<BOP>
Q39E95
Q2L058
RL21_BORA1
50S ribosomal protein L21
Bordetella
<M><Y><A><V><V><K><T><G><G><K><Q><Y><R><V><A><A><G><E><K><L><K><V><E><Q><I><P><A><D><I><G><Q><E><I><T><L><D><Q><V><L><S><V><G><E><G><D><Q><L><K><V><G><T><P><L><V><A><G><A><V><V><K><A><T><V><L><A><H><G><R><H><D><K><V><K><I><F><K><M><R><R><R><K><H><Y><Q><K><R><Q><G><H><R><Q><N><Y><T><E><I><R><I><E><A><I><T><A>
This protein binds to 23S rRNA in the presence of protein L20.<BOP>
Q2L058
P72656
RNE_SYNY3
Ribonuclease E/G
unclassified Synechocystis
<M><P><K><Q><I><V><I><A><E><K><H><Q><V><A><A><V><F><W><K><D><Q><I><Q><E><L><V><V><S><T><G><S><Q><Q><V><G><D><I><Y><L><G><L><V><D><N><I><L><P><S><I><D><A><A><F><I><N><I><G><D><T><E><K><N><G><F><I><H><V><S><D><L><G><P><V><R><L><R><R><T><A><G><S><I><S><E><L><L><S><P><Q><Q><R><V><L><V><Q><V><M><K><E><P><T><G><N><K><G><P><R...
CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading n...
P72656
Q9Z615
FENR_BUCAP
Flavodoxin--NADP reductase
Buchnera
<M><N><P><W><I><N><A><N><V><L><K><V><H><K><W><T><Q><N><L><F><S><L><I><L><N><A><E><I><A><P><F><Q><A><G><Q><F><T><K><L><A><L><N><E><E><N><I><N><F><S><N><N><V><K><K><K><K><I><Q><R><A><Y><S><F><V><N><A><P><S><N><K><N><L><E><I><Y><I><V><R><I><L><N><G><K><L><S><N><L><L><Y><N><L><K><S><G><D><N><L><F><I><K><E><K><S><F><G><F><F...
Transports electrons between flavodoxin or ferredoxin and NADPH.<BOP>
Q9Z615
Q1QSR9
TRMB_CHRSD
tRNA(m7G46)-methyltransferase
Chromohalobacter
<M><S><D><S><S><S><S><S><E><N><A><P><A><T><P><E><S><P><G><R><P><P><R><G><I><K><S><Y><V><L><R><A><G><R><M><T><A><A><Q><S><R><G><L><E><E><V><W><P><R><L><G><L><S><V><A><E><G><R><Q><S><L><E><A><L><F><G><R><R><A><P><C><V><V><E><V><G><F><G><M><G><Q><S><L><V><E><Q><A><A><A><N><P><E><T><D><F><I><G><I><E><V><H><A><P><G><V><G><K...
Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.<BOP>
Q1QSR9
Q1QTJ9
HEM6_CHRSD
Oxygen-dependent coproporphyrinogen-III oxidase
Chromohalobacter
<M><A><H><P><H><L><D><K><V><K><E><Y><L><L><D><L><Q><D><R><L><C><D><G><L><A><A><E><E><G><D><T><A><F><R><E><D><S><W><T><R><E><A><G><G><G><G><R><S><R><V><I><E><N><G><E><V><F><E><K><G><G><V><N><F><S><H><V><F><G><E><R><L><P><A><S><A><S><A><A><R><P><E><L><A><G><R><S><F><H><A><V><G><V><S><W><V><L><H><P><R><N><P><H><V><P><T><A...
Involved in the heme biosynthesis. Catalyzes the aerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen-III to yield the vinyl groups in protoporphyrinogen-IX.<BOP>
Q1QTJ9
Q48FA7
RIMO_PSE14
Ribosome maturation factor RimO
Pseudomonas
<M><S><T><V><T><T><P><S><A><P><K><V><G><F><V><S><L><G><C><P><K><A><L><V><D><S><E><R><I><L><T><Q><L><R><M><E><G><Y><E><V><V><A><T><Y><E><D><A><D><V><V><V><V><N><T><C><G><F><I><D><T><A><K><A><E><S><L><E><V><I><G><E><A><I><K><E><N><G><K><V><I><V><T><G><C><M><G><V><D><A><N><V><I><R><D><V><H><P><S><V><L><S><V><T><G><P><Q><Q...
Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12.<BOP>
Q48FA7
Q8ZTE6
NTPTH_PYRAE
Nucleoside triphosphate phosphohydrolase
Pyrobaculum
<M><T><W><R><E><R><A><E><L><R><I><G><I><S><G><M><P><G><V><G><K><T><T><L><V><L><K><I><A><E><L><A><R><S><R><V><K><V><C><G><F><V><T><V><E><V><R><E><G><G><T><R><I><G><F><D><V><V><D><L><A><N><G><R><R><M><A><L><A><R><V><G><R><G><E><P><S><V><G><K><Y><V><V><N><L><E><A><C><N><V><I><S><E><A><L><R><R><E><C><D><L><K><I><I><D><E><I...
Has nucleotide phosphatase activity towards ATP, GTP, CTP, TTP and UTP. May hydrolyze nucleoside diphosphates with lower efficiency.<BOP>
Q8ZTE6
E0ZS47
UREG_ORYSI
Urease accessory protein G
Oryza sativa
<M><A><S><H><D><H><D><H><H><H><H><H><H><H><S><H><D><D><G><D><H><H><H><S><H><H><Q><D><G><S><H><G><G><G><G><G><S><W><V><G><E><D><G><R><V><W><H><S><H><D><G><L><A><P><H><S><H><E><P><I><Y><S><P><G><D><F><S><K><R><A><P><P><L><I><S><R><R><F><A><E><R><A><F><T><V><G><I><G><G><P><V><G><T><G><K><T><A><L><M><L><A><L><C><R><S><L><R...
Required for the maturation and activation of urease via the functional incorporation of the urease nickel metallocenter.<BOP>
E0ZS47
Q3M5D2
RS20_TRIV2
30S ribosomal protein S20
Trichormus
<M><C><A><N><N><K><S><A><L><K><R><A><Q><I><A><E><R><N><R><V><R><N><K><T><Y><K><S><S><V><K><T><L><M><K><N><Y><L><S><A><V><Q><A><Y><A><A><N><P><T><P><E><S><K><Q><E><A><Q><T><R><L><A><A><A><Y><S><R><I><D><K><A><V><K><R><G><I><L><H><P><N><N><G><A><R><K><K><S><R><L><A><S><K><L><K><P><I><E><Q><T><A>
Binds directly to 16S ribosomal RNA.<BOP>
Q3M5D2
Q09013
DMPK_HUMAN
Myotonic dystrophy protein kinase
Homo
<M><S><A><E><V><R><L><R><R><L><Q><Q><L><V><L><D><P><G><F><L><G><L><E><P><L><L><D><L><L><L><G><V><H><Q><E><L><G><A><S><E><L><A><Q><D><K><Y><V><A><D><F><L><Q><W><A><E><P><I><V><V><R><L><K><E><V><R><L><Q><R><D><D><F><E><I><L><K><V><I><G><R><G><A><F><S><E><V><A><V><V><K><M><K><Q><T><G><Q><V><Y><A><M><K><I><M><N><K><W><D><M...
Non-receptor serine/threonine protein kinase which is necessary for the maintenance of skeletal muscle structure and function. May play a role in myocyte differentiation and survival by regulating the integrity of the nuclear envelope and the expression of muscle-specific genes. May also phosphorylate PPP1R12A and inhi...
Q09013
Q7NK24
CYSH_GLOVI
PAdoPS reductase
Gloeobacter
<M><N><L><L><Q><D><Q><P><A><M><G><I><D><Q><T><T><L><E><H><L><A><R><Q><W><E><D><L><A><P><E><A><I><L><A><E><A><V><R><C><F><G><D><K><L><V><L><A><S><A><F><G><P><E><S><I><I><L><L><D><M><L><V><K><V><W><P><R><P><Q><A><F><F><L><E><T><G><F><H><F><P><E><T><L><A><L><K><D><R><V><L><A><R><F><P><Q><L><Q><L><E><V><V><G><P><L><M><S><V...
Catalyzes the formation of sulfite from phosphoadenosine 5'-phosphosulfate (PAPS) using thioredoxin as an electron donor.<BOP>
Q7NK24
A9KNK1
UPPP_LACP7
Undecaprenyl pyrophosphate phosphatase
Lachnospiraceae
<M><D><F><I><E><L><L><K><V><I><F><L><G><I><V><E><G><I><T><E><W><L><P><I><S><S><T><G><H><L><L><L><V><D><E><F><L><K><V><N><L><S><K><D><F><M><S><M><F><N><V><V><I><Q><L><G><A><I><L><A><V><V><V><L><F><F><K><K><L><W><P><F><S><K><E><E><K><N><F><I><K><K><D><T><F><T><L><W><F><K><I><V><V><A><C><I><P><G><I><V><M><I><P><F><D><S><K...
Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin.<BOP>
A9KNK1
P25066
P43_XENBO
Thesaurin-B
Xenopus
<M><Q><N><V><G><P><T><E><P><S><K><S><Q><V><F><R><C><P><A><A><G><C><K><A><V><Y><R><K><E><G><K><L><R><D><H><M><A><G><H><S><E><Q><K><L><W><K><C><G><K><K><D><C><G><K><M><F><A><R><K><R><Q><I><Q><K><H><M><K><R><H><L><T><L><K><K><H><S><C><P><T><A><G><C><K><M><T><F><S><T><K><K><S><L><S><R><H><K><L><Y><K><H><G><D><A><V><P><L><K...
p43 is a 5S RNA binding protein which is a major constituent of oocytes and comprises part of a 42S ribonucleoprotein storage particle.<BOP>
P25066
Q3MAP6
Y2322_TRIV2
Nucleoid-associated protein Ava_2322
Trichormus
<M><T><G><K><G><Q><G><F><G><F><G><L><G><K><M><K><E><L><A><E><A><F><K><K><A><Q><Q><V><Q><E><G><A><K><R><L><Q><E><E><L><E><Q><M><E><I><L><G><E><A><G><G><G><L><V><K><V><I><V><S><G><N><Q><E><P><K><R><V><E><I><S><P><D><A><L><A><Q><G><A><D><L><L><S><D><L><V><T><A><A><M><K><D><A><Y><I><K><S><T><A><T><M><R><E><R><M><E><D><L><T...
Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection.<BOP>
Q3MAP6
Q9H6K4
OPA3_HUMAN
Optic atrophy 3 protein
Homo
<M><V><V><G><A><F><P><M><A><K><L><L><Y><L><G><I><R><Q><V><S><K><P><L><A><N><R><I><K><E><A><A><R><R><S><E><F><F><K><T><Y><I><C><L><P><P><A><Q><L><Y><H><W><V><E><M><R><T><K><M><R><I><M><G><F><R><G><T><V><I><K><P><L><N><E><E><A><A><A><E><L><G><A><E><L><L><G><E><A><T><I><F><I><V><G><G><G><C><L><V><L><E><Y><W><R><H><Q><A><Q...
May play some role in mitochondrial processes.<BOP>
Q9H6K4
O57776
FTSZ1_PYRHO
Cell division protein FtsZ 1
Pyrococcus
<M><L><K><L><V><E><N><V><V><E><R><V><S><S><E><E><T><K><V><Q><E><V><Q><V><P><Q><S><S><I><D><E><E><L><K><K><I><V><E><Q><I><K><A><R><I><H><V><V><G><V><G><G><A><G><C><N><T><V><N><R><M><M><E><V><G><V><T><G><A><K><I><I><A><V><N><T><D><A><Q><D><L><L><K><V><K><A><H><Q><K><I><L><I><G><K><E><I><T><R><G><L><G><A><G><N><D><P><K><I...
Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new ce...
O57776
Q576B4
NU5M_BOSIN
NADH dehydrogenase subunit 5
Bos
<M><N><M><F><S><S><L><S><L><V><T><L><L><L><L><T><M><P><I><M><M><M><S><L><N><T><Y><K><P><S><N><Y><P><L><Y><V><K><T><A><I><S><Y><A><F><I><T><S><M><I><P><T><M><M><F><I><H><S><G><Q><E><L><I><I><S><N><W><H><W><L><T><I><Q><T><L><K><L><S><L><S><F><K><M><D><Y><F><S><M><M><F><T><P><V><A><L><F><V><T><W><S><I><M><E><F><S><M><W><Y...
Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) which catalyzes electron transfer from NADH through the respiratory chain, using ubiquinone as an electron acceptor. Essential for the catalytic activity and assembly of complex I.<BOP>
Q576B4
A3Q192
PSA_MYCSJ
Proteasome core protein PrcA
unclassified Mycobacterium
<M><S><F><P><Y><F><I><S><P><E><Q><A><M><R><E><R><S><E><L><A><R><K><G><I><A><R><G><R><S><V><V><A><L><A><Y><A><D><G><V><L><F><V><A><E><N><P><S><R><S><L><Q><K><V><S><E><L><Y><D><R><V><G><F><A><A><V><G><R><F><N><E><F><N><N><L><R><S><G><G><I><R><F><A><D><T><Q><G><Y><A><Y><S><R><R><D><V><T><G><R><Q><L><A><N><V><Y><A><Q><T><L...
Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation.<BOP>
A3Q192
Q87TS0
YIDD_PSESM
Putative membrane protein insertion efficiency factor
Pseudomonas
<M><R><K><L><A><L><V><P><I><Q><F><Y><R><Y><A><I><S><P><L><M><A><S><H><C><R><F><Y><P><S><C><S><C><Y><A><Y><E><A><I><D><N><H><G><L><L><R><G><G><W><L><S><I><R><R><L><G><R><C><H><P><W><N><P><G><G><Y><D><P><V><P><A><V><P><T><S><R><S><S><S><M><A><E>
Could be involved in insertion of integral membrane proteins into the membrane.<BOP>
Q87TS0
P23572
CDK1_DROME
p34 protein kinase
Sophophora
<M><E><D><F><E><K><I><E><K><I><G><E><G><T><Y><G><V><V><Y><K><G><R><N><R><L><T><G><Q><I><V><A><M><K><K><I><R><L><E><S><D><D><E><G><V><P><S><T><A><I><R><E><I><S><L><L><K><E><L><K><H><E><N><I><V><C><L><E><D><V><L><M><E><E><N><R><I><Y><L><I><F><E><F><L><S><M><D><L><K><K><Y><M><D><S><L><P><V><D><K><H><M><E><S><E><L><V><R><S...
Plays a key role in the control of the eukaryotic cell cycle . It is required in higher cells for entry into S-phase and mitosis . In embryos, promotes the release of Rif1 from chromatin during mid-blastula transition . p34 is a component of the kinase complex that phosphorylates the repetitive C-terminus of RNA polyme...
P23572
Q7LYX6
MALG_THELN
Trehalose/maltose transport system permease protein MalG
Thermococcus
<M><R><E><E><V><L><K><R><I><L><L><I><I><G><A><I><L><M><A><I><I><C><L><F><P><F><I><W><M><I><V><V><S><F><A><E><D><P><T><F><L><G><S><P><L><V><E><Y><K><S><T><L><E><N><Y><V><R><V><L><S><D><P><T><L><H><F><P><A><Y><L><K><N><S><I><I><I><A><S><L><V><T><L><T><T><V><S><I><S><S><L><A><A><Y><A><V><S><R><I><E><F><K><G><R><L><L><I><P...
Part of the ABC transporter complex MalEFGK involved in trehalose/maltose import. Responsible for the translocation of the substrate across the membrane.<BOP>
Q7LYX6
Q39085
DIM_ARATH
Protein ENHANCED VERY-LOW-FLUENCE RESPONSE 1
Arabidopsis
<M><S><D><L><Q><T><P><L><V><R><P><K><R><K><K><T><W><V><D><Y><F><V><K><F><R><W><I><I><V><I><F><I><V><L><P><F><S><A><T><F><Y><F><L><I><Y><L><G><D><M><W><S><E><S><K><S><F><E><K><R><Q><K><E><H><D><E><N><V><K><K><V><I><K><R><L><K><G><R><D><A><S><K><D><G><L><V><C><T><A><R><K><P><W><I><A><V><G><M><R><N><V><D><Y><K><R><A><R><H...
Plays a critical role in the general process of plant cell elongation. Involved in the synthesis of campesterol, an early precursor of brassinolide. Required for the conversion of 24-methylenecholesterol to campesterol and for the conversion of isofucosterol to sitosterol. Necessary for both the isomerization and reduc...
Q39085
A0T0L2
PSAC_PHATC
PsaC
Phaeodactylum
<M><S><H><T><V><K><I><Y><D><T><C><I><G><C><T><Q><C><V><R><A><C><P><T><D><V><L><E><M><V><P><W><D><G><C><K><A><G><Q><I><A><S><S><P><R><V><E><D><C><V><G><C><K><R><C><E><T><A><C><P><T><D><F><L><S><V><R><V><Y><L><G><A><E><T><T><R><S><L><G><L><A><Y>
Apoprotein for the two 4Fe-4S centers FA and FB of photosystem I (PSI); essential for photochemical activity. FB is the terminal electron acceptor of PSI, donating electrons to ferredoxin. The C-terminus interacts with PsaA/B/D and helps assemble the protein into the PSI complex. Required for binding of PsaD and PsaE t...
A0T0L2
Q1JS90
RN2VB_ODOVE
2VEb
Odorrana
<M><F><T><L><K><K><S><F><L><L><L><F><F><L><G><T><I><T><L><S><L><C><E><E><E><R><G><A><D><D><D><D><G><E><E><E><V><K><R><G><I><M><D><T><V><K><G><V><A><K><T><V><A><A><S><L><L><D><K><L><K><C><K><I><T><G><C>
Antimicrobial peptide.<BOP>
Q1JS90
Q980F0
MOAA_SACS2
Molybdenum cofactor biosynthesis protein A
Saccharolobus
<M><I><D><R><F><G><R><P><L><E><D><L><R><I><T><L><T><H><A><C><N><F><E><C><F><F><C><H><M><E><G><E><E><G><D><N><Y><L><L><S><K><E><D><I><L><L><V><A><K><V><A><R><K><F><G><I><N><S><V><K><L><T><G><G><E><P><T><L><R><R><D><L><V><E><I><V><R><G><L><K><Q><L><G><Y><E><D><V><S><M><T><T><N><G><F><L><L><K><D><L><A><H><K><L><K><L><A><G...
Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate.<BOP>
Q980F0
Q5QYI0
RPOZ_IDILO
Transcriptase subunit omega
Idiomarina
<M><A><R><V><T><V><E><D><A><V><D><R><V><G><N><R><F><D><L><I><L><L><A><S><R><R><A><R><Q><L><A><N><G><K><E><P><L><V><E><T><K><N><E><K><P><T><V><I><A><L><R><E><I><E><Q><G><L><I><D><N><E><R><L><D><I><E><D><Q><A><A><Q><K><Q><Q><D><A><E><E><L><R><A><V><D><A><L><R><G><I><E>
Promotes RNA polymerase assembly. Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.<BOP>
Q5QYI0
Q10357
CCS1_SCHPO
Superoxide dismutase 1 copper chaperone
Schizosaccharomyces
<M><F><E><V><E><Y><L><I><K><D><C><D><D><V><N><K><N><T><L><E><Q><E><F><Q><D><L><N><I><E><D><W><K><W><D><A><A><T><G><Q><L><I><V><K><G><S><V><S><P><S><K><V><L><R><R><L><E><N><A><T><S><K><P><I><L><I><R><G><A><S><N><K><E><S><G><V><S><I><L><Y><E><A><N><E><D><I><T><Q><I><P><K><V><Y><G><L><C><R><F><I><P><T><E><E><K><I><F><L><D...
Copper chaperone for superoxide dismutase 1 (sod1). Binds copper ions and delivers them specifically to sod1. Also has a role in cell protection against copper ion toxicity during conditions of copper excess. The C-terminal region is thought to act specifically in this sequestration role.<BOP>
Q10357
Q30S45
EFP_SULDN
Elongation factor P
Sulfurimonas
<M><A><T><I><G><M><G><D><I><K><K><N><I><R><L><I><I><G><E><V><P><C><K><V><I><E><F><Q><H><V><K><P><G><K><G><A><A><F><V><R><M><K><A><K><S><F><L><N><G><R><V><F><E><K><T><V><H><A><G><D><K><F><E><V><P><E><I><T><F><K><T><M><Q><Y><L><Y><D><D><G><E><Q><Y><Q><F><M><D><N><D><S><Y><E><Q><I><G><L><S><Y><E><Q><C><D><D><A><S><K><W><F...
Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.<BOP>
Q30S45
Q8RGC8
FBPC_FUSNN
Fe(3+) ions import ATP-binding protein FbpC
Fusobacterium
<M><S><V><N><I><K><I><E><N><A><Q><K><R><Y><G><D><N><I><I><I><E><N><L><S><L><D><I><K><Q><G><E><F><F><T><L><L><G><P><S><G><C><G><K><T><T><L><L><R><M><I><A><G><F><N><S><I><E><K><G><N><F><Y><F><N><E><K><R><I><N><D><L><D><P><A><K><R><N><I><G><M><V><F><Q><N><Y><A><I><F><P><H><L><T><V><E><Q><N><V><E><F><G><L><K><N><R><K><V><S...
Part of the ABC transporter complex FbpABC involved in Fe(3+) ions import. Responsible for energy coupling to the transport system.<BOP>
Q8RGC8
A5FS53
ISPE_DEHMB
4-(cytidine-5'-diphospho)-2-C-methyl-D-erythritol kinase
Dehalococcoides
<M><L><T><L><L><A><P><A><K><V><N><L><S><L><E><V><L><Y><R><R><K><D><G><Y><H><E><L><R><S><I><I><Q><S><L><S><L><C><D><R><L><S><F><S><P><S><K><T><V><H><I><S><S><D><S><Q><D><W><Q><A><D><L><S><L><V><S><K><A><V><E><L><F><S><E><R><C><G><Q><N><T><G><V><N><L><K><I><A><K><R><I><P><L><V><S><G><L><G><G><D><S><S><C><A><A><A><V><L><K...
Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.<BOP>
A5FS53
Q1GCN5
HSLV_RUEST
ATP-dependent protease subunit HslV
unclassified Ruegeria
<M><A><E><D><Q><F><P><G><W><H><G><T><T><I><I><G><V><R><K><G><D><E><V><V><V><A><G><D><G><Q><V><S><L><G><Q><T><V><I><K><G><S><A><R><K><V><R><R><L><S><P><G><G><Y><D><V><V><A><G><F><A><G><S><T><A><D><A><F><T><L><L><E><R><L><E><A><K><L><E><A><T><P><G><Q><L><Q><R><A><S><V><E><L><A><K><D><W><R><T><D><K><Y><L><Q><K><L><E><A><M...
Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery.<BOP>
Q1GCN5
P53869
MRX7_YEAST
Mitochondrial organization of gene expression protein 7
Saccharomyces
<M><P><P><R><S><I><E><E><W><F><Y><Y><K><L><L><S><S><P><G><F><H><R><F><V><R><K><V><Y><R><K><V><N><G><I><K><E><D><P><F><T><D><Q><S><T><A><F><Q><Y><L><Y><K><P><T><P><R><Q><K><F><K><A><L><R><L><L><F><W><D><E><M><R><S><T><F><G><F><R><R><R><L><G><D><R><F><K><K><D>
Component of MIOREX complexes, large expressome-like assemblies of ribosomes with factors involved in all the steps of post-transcriptional gene expression.<BOP>
P53869
Q0TLZ4
MNME_CLOP1
tRNA modification GTPase MnmE
Clostridium
<M><K><E><F><D><T><I><A><A><I><A><T><A><L><G><E><G><G><I><A><I><I><R><V><S><G><N><K><A><L><E><I><V><N><K><I><F><R><G><I><N><G><K><D><L><L><D><I><K><P><Y><T><M><R><Y><G><H><M><I><D><E><N><N><E><I><I><D><E><V><I><V><S><F><M><K><G><P><R><S><F><T><A><E><D><T><V><E><I><N><C><H><G><G><I><V><A><T><N><K><V><L><Q><N><V><I><K><A...
Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.<BOP>
Q0TLZ4
A0KU20
TORD_SHESA
Chaperone protein TorD
Shewanella
<M><S><N><V><D><I><N><H><A><R><A><L><V><Y><Q><L><L><S><S><L><F><A><R><E><I><D><E><Q><R><L><K><Q><L><T><S><E><Q><A><Q><Q><F><W><T><Q><L><G><Y><A><P><E><F><S><A><S><V><A><S><I><Q><K><V><L><N><G><L><T><S><D><E><A><L><L><E><L><A><A><D><Y><C><G><L><F><L><V><G><T><K><H><S><A><S><P><Y><A><S><L><Y><L><N><R><E><E><E><P><L><L><F...
Involved in the biogenesis of TorA. Acts on TorA before the insertion of the molybdenum cofactor and, as a result, probably favors a conformation of the apoenzyme that is competent for acquiring the cofactor.<BOP>
A0KU20
Q9F6B2
SLYA_EDWTA
Edwardsiella hemolysin activator
Edwardsiella
<M><E><S><T><L><G><S><D><L><S><R><L><V><R><V><W><R><A><L><I><D><Q><R><L><K><P><L><E><L><T><Q><T><H><W><V><T><L><Y><N><I><H><R><L><P><P><D><Q><S><Q><I><Q><L><A><K><A><I><G><I><E><Q><P><S><L><V><R><T><L><D><Q><L><E><D><K><G><L><I><T><R><H><I><C><A><N><D><R><R><A><K><R><I><K><L><T><D><D><A><E><P><V><I><K><E><V><T><G><V><I...
Transcription regulator that can specifically activate or repress expression of target genes.<BOP>
Q9F6B2
A4SG06
GCSPA_CHLPM
Glycine dehydrogenase (aminomethyl-transferring) subunit 1
Chlorobium
<M><P><F><I><I><N><T><D><S><D><R><A><E><M><L><A><A><A><G><A><A><S><F><N><D><L><I><A><D><I><P><E><E><I><R><L><K><K><S><L><D><L><A><P><A><L><D><E><M><A><V><R><R><Q><L><E><S><L><A><A><R><N><R><S><T><A><G><Y><V><S><F><L><G><G><G><A><Y><D><Q><F><I><P><S><A><I><R><A><I><V><S><R><S><E><F><Y><T><A><Y><T><P><Y><Q><A><E><V><S><Q...
The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.<BOP>
A4SG06