accession
stringlengths
6
10
name
stringlengths
6
11
Full Name
stringlengths
1
147
⌀
taxon
stringlengths
3
46
⌀
sequence
stringlengths
48
2.3k
function
stringlengths
11
1.34k
AlphaFoldDB
stringlengths
6
10
Q03200
LIRP1_ORYSJ
Light-regulated protein, chloroplastic
Oryza sativa
<M><Q><T><A><A><S><S><V><V><G><L><S><A><V><L><P><A><A><V><K><G><R><S><L><Q><I><Q><A><P><R><R><V><A><L><R><V><R><A><A><A><A><A><V><A><V><E><A><A><E><V><D><Y><S><S><N><I><S><V><F><P><M><E><A><C><D><L><I><G><G><E><A><C><N><V><Q><M><Y><P><E><A><K><L><S><S><S><A><A><V><A><V><S><R><A><A><A><E><E><V><D><R><D><Y><L><S><Y><D><E...
Thylakoid-determinant subunit of high molecular weight LFNRs-containing protein complexes.<BOP>
Q03200
A7N655
PYRC_VIBC1
Dihydroorotase
Vibrio
<M><T><T><L><T><I><T><R><P><D><D><W><H><V><H><L><R><D><G><E><V><L><K><D><T><V><R><D><I><S><R><Y><N><G><R><A><L><I><M><P><N><T><V><P><P><V><T><N><T><E><M><A><L><A><Y><R><D><R><I><L><A><E><Q><H><G><E><Q><F><E><P><L><M><A><L><Y><L><T><D><N><T><T><P><D><E><I><R><K><A><K><A><T><G><K><I><V><A><A><K><L><Y><P><A><G><A><T><T><N...
Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.<BOP>
A7N655
P34814
PYG_AGLNE
Phycobilisome rod-core linker polypeptide cpcG
Aglaothamnion
<M><S><I><P><I><L><N><Y><S><L><S><T><Q><N><Q><R><V><N><G><F><E><G><L><P><G><D><E><L><P><K><I><Y><T><T><D><N><L><P><T><S><I><E><M><D><E><I><I><W><A><A><Y><R><Q><I><F><S><E><H><Q><M><L><S><S><C><M><D><R><F><L><E><S><Q><L><R><F><N><Q><I><K><V><K><D><F><I><K><G><L><V><L><S><S><A><F><R><N><L><N><Y><D><C><N><N><N><Y><R><F><V...
Linker polypeptides determine the state of aggregation and the location of the disk-shaped phycobiliprotein units within the phycobilisome and modulate their spectroscopic properties in order to mediate a directed and optimal energy transfer.<BOP>
P34814
Q87L92
CYSH_VIBPA
PAdoPS reductase
Vibrio
<M><L><D><S><V><A><S><K><P><E><L><A><E><L><L><T><L><T><K><T><E><Q><I><L><R><L><A><Q><I><N><V><E><L><E><P><L><S><A><Q><E><R><V><K><W><A><L><E><N><L><D><G><E><F><A><V><S><S><S><F><G><I><Q><A><A><V><M><L><H><L><V><T><Q><E><K><P><D><I><P><I><I><L><T><D><T><G><Y><L><F><A><E><T><Y><R><F><I><D><E><L><T><E><K><L><N><L><N><L><K...
Catalyzes the formation of sulfite from phosphoadenosine 5'-phosphosulfate (PAPS) using thioredoxin as an electron donor.<BOP>
Q87L92
O76878
RIPL_DROME
Rab-interacting lysosomal protein-like
Sophophora
<M><P><G><F><H><L><N><E><M><G><E><M><V><L><D><A><I><D><D><I><G><V><V><D><V><Y><D><L><A><S><D><I><G><K><E><Y><E><R><I><M><D><R><F><G><T><D><A><V><S><G><L><M><P><K><I><I><N><T><L><E><L><L><E><A><L><A><T><K><N><E><R><E><N><A><T><I><Q><E><L><R><D><K><V><A><Q><L><E><S><E><K><L><E><K><A><E><F><R><R><R><F><D><K><E><L><E><L><I...
May have a role in lysosome distribution by interacting with Arl8.<BOP>
O76878
Q9CPY7
AMPL_MOUSE
Prolyl aminopeptidase
Mus
<M><Y><L><L><P><L><P><A><A><A><R><V><A><L><R><R><L><G><V><R><G><L><W><D><R><G><L><S><T><A><D><M><T><K><G><L><V><L><G><I><Y><A><K><D><K><D><D><D><L><P><Q><F><T><S><A><G><E><S><F><N><K><L><V><S><G><K><L><R><E><M><L><N><I><S><G><P><P><L><K><A><G><K><T><R><T><F><Y><G><L><H><Q><D><F><P><S><V><V><V><V><G><L><G><K><R><S><A><G...
Cytosolic metallopeptidase that catalyzes the removal of unsubstituted N-terminal hydrophobic amino acids from various peptides. The presence of Zn(2+) ions is essential for the peptidase activity, and the association with other cofactors can modulate the substrate spectificity of the enzyme. For instance, in the prese...
Q9CPY7
Q1LR89
YBEY_CUPMC
Endoribonuclease YbeY
Cupriavidus
<M><V><A><L><L><A><E><H><T><D><T><R><Q><Q><A><G><L><L><V><R><P><D><N><S><D><A><L><S><V><A><V><T><A><T><P><I><V><T><T><T><G><T><P><A><T><P><P><A><L><E><L><D><V><Q><H><G><D><G><V><S><K><R><N><G><L><P><S><R><K><Q><I><E><K><W><V><K><S><A><L><Y><A><D><A><A><L><T><V><R><F><V><D><E><T><E><G><R><T><L><N><R><S><Y><R><G><K><D><Y...
Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.<BOP>
Q1LR89
C0R2X3
COXX_WOLWR
Heme O synthase
unclassified Wolbachia
<M><Y><T><S><V><L><L><N><V><E><S><T><I><L><D><F><W><R><L><L><K><P><R><I><M><Y><L><V><V><F><T><A><V><A><G><M><V><T><A><P><G><S><M><H><P><F><L><A><L><I><S><L><I><C><V><A><L><G><S><G><S><A><G><A><I><N><M><W><Y><D><R><D><I><D><L><L><M><E><R><T><K><N><R><P><I><P><S><G><R><V><S><A><E><S><A><L><E><F><G><I><T><L><G><I><L><S><V...
Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group.<BOP>
C0R2X3
Q8BTR5
DUS28_MOUSE
Dual specificity phosphatase 28
Mus
<M><G><T><S><E><A><A><P><P><P><F><A><R><V><A><P><A><L><F><I><G><N><A><R><A><A><G><A><T><E><L><L><V><R><A><G><I><T><L><C><V><N><V><S><R><Q><Q><P><G><P><R><A><P><G><V><A><E><L><R><V><P><V><F><D><D><P><A><E><D><L><L><T><H><L><E><P><T><C><A><A><M><E><A><A><V><R><D><G><G><S><C><L><V><Y><C><K><N><G><R><S><R><S><A><A><V><C><T...
Has phosphatase activity with the synthetic substrate 6,8-difluoro-4-methylumbelliferyl phosphate (in vitro). Has almost no detectable activity with phosphotyrosine, even less activity with phosphothreonine and displays complete lack of activity with phosphoserine. The poor activity with phosphotyrosine may be due to s...
Q8BTR5
Q9XSZ6
FCERG_PIG
IgE Fc receptor subunit gamma
Sus
<M><I><P><A><V><V><L><L><L><L><L><L><V><E><Q><A><A><A><L><G><E><P><Q><L><C><Y><I><L><D><A><I><L><F><L><Y><G><I><V><L><T><L><L><Y><C><R><L><K><L><Q><V><R><K><A><A><I><D><S><Y><E><K><S><D><G><V><Y><T><G><L><S><T><R><N><Q><E><T><Y><E><T><L><K><H><E><K><P><P><Q>
Adapter protein containing an immunoreceptor tyrosine-based activation motif (ITAM) that transduces activation signals from various immunoreceptors. As a component of the high-affinity immunoglobulin E (IgE) receptor, mediates allergic inflammatory signaling in mast cells. As a constitutive component of interleukin-3 r...
Q9XSZ6
A9MJ94
5DNU_SALAR
Nucleoside 5'-monophosphate phosphohydrolase
Salmonella
<M><K><Q><S><H><F><F><A><H><L><S><R><L><K><L><I><N><R><W><P><L><M><R><N><V><R><T><E><N><V><S><E><H><S><L><Q><V><A><M><V><A><H><A><L><A><A><I><K><N><R><K><F><G><G><Q><L><N><A><E><H><I><A><L><L><A><M><Y><H><D><T><S><E><V><L><T><G><D><L><P><T><P><V><K><Y><F><N><S><Q><I><A><Q><E><Y><K><A><I><E><K><I><A><Q><Q><K><L><V><D><M...
Catalyzes the strictly specific dephosphorylation of 2'-deoxyribonucleoside 5'-monophosphates.<BOP>
A9MJ94
A0A0K2G9F6
UBACT_NITMO
Prokaryotic ubiquitin-like protein UBact
Nitrospira
<M><N><M><R><Y><T><L><M><P><E><R><R><E><G><P><V><D><P><M><P><Q><S><P><S><P><S><D><E><G><G><G><P><R><R><P><E><T><G><S><P><D><K><D><N><L><L><K><R><M><R><K><V><D><P><K><Q><A><E><R><Y><R><Q><R><T><G><E>
May function as a protein modifier covalently attached to lysine residues of substrate proteins. This may serve to target the modified proteins for degradation by proteasomes.<BOP>
A0A0K2G9F6
Q5PLH2
EPMA_SALPA
EF-P-lysine lysyltransferase
Salmonella
<M><S><E><T><A><T><W><Q><P><S><A><S><I><P><N><L><L><K><R><A><A><I><M><T><E><I><R><R><F><F><A><D><R><G><V><L><E><V><E><T><P><C><M><S><Q><A><T><V><T><D><I><H><L><F><P><F><E><T><R><F><V><G><P><G><H><S><Q><G><M><N><L><Y><L><M><T><S><P><E><Y><H><M><K><R><L><L><A><A><G><C><G><P><V><F><Q><L><C><R><S><F><R><N><E><E><M><G><R><H...
With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P) on 'Lys-34'. Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta-lysyl moiety is then transferred to the epsilon-amino...
Q5PLH2
O60678
ANM3_HUMAN
Heterogeneous nuclear ribonucleoprotein methyltransferase-like protein 3
Homo
<M><C><S><L><A><S><G><A><T><G><G><R><G><A><V><E><N><E><E><D><L><P><E><L><S><D><S><G><D><E><A><A><W><E><D><E><D><D><A><D><L><P><H><G><K><Q><Q><T><P><C><L><F><C><N><R><L><F><T><S><A><E><E><T><F><S><H><C><K><S><E><H><Q><F><N><I><D><S><M><V><H><K><H><G><L><E><F><Y><G><Y><I><K><L><I><N><F><I><R><L><K><N><P><T><V><E><Y><M><N...
Protein-arginine N-methyltransferase that catalyzes both the monomethylation and asymmetric dimethylation of the guanidino nitrogens of arginine residues in target proteins, and therefore falls into the group of type I methyltransferases (Probable). May regulate retinoic acid synthesis and signaling by inhibiting ALDH1...
O60678
Q96HU8
DIRA2_HUMAN
Distinct subgroup of the Ras family member 2
Homo
<M><P><E><Q><S><N><D><Y><R><V><A><V><F><G><A><G><G><V><G><K><S><S><L><V><L><R><F><V><K><G><T><F><R><E><S><Y><I><P><T><V><E><D><T><Y><R><Q><V><I><S><C><D><K><S><I><C><T><L><Q><I><T><D><T><T><G><S><H><Q><F><P><A><M><Q><R><L><S><I><S><K><G><H><A><F><I><L><V><Y><S><I><T><S><R><Q><S><L><E><E><L><K><P><I><Y><E><Q><I><C><E><I...
Displays low GTPase activity and exists predominantly in the GTP-bound form.<BOP>
Q96HU8
Q9SQ80
G2OX1_PEA
Protein SLENDER
Pisum
<M><V><L><L><S><K><P><T><S><E><Q><Y><T><Y><V><R><N><N><M><P><I><T><F><S><S><S><I><P><L><V><D><L><S><K><P><D><A><K><T><L><I><V><K><A><C><E><D><F><G><F><F><K><V><I><N><H><G><I><P><L><D><A><I><S><Q><L><E><S><E><A><F><K><F><F><S><L><P><Q><T><E><K><E><K><A><G><P><A><N><P><F><G><Y><G><N><K><R><I><G><L><N><G><D><I><G><W><I><E...
Catalyzes the 2-beta-hydroxylation of several biologically active gibberellins, leading to the homeostatic regulation of their endogenous level. Catabolism of gibberellins (GAs) plays a central role in plant development. Converts GA9/GA20 to GA51/GA29 and GA4/GA1 to GA34/GA8.<BOP>
Q9SQ80
P45626
GLNA2_RHIML
Glutamine synthetase II
Sinorhizobium
<M><T><K><Y><K><L><E><Y><I><W><L><D><A><T><R><P><Y><Q><T><L><R><G><K><T><Q><I><K><E><F><D><A><F><P><T><L><E><Q><L><P><L><W><G><F><D><G><S><S><T><L><Q><A><E><G><R><T><S><D><C><V><L><K><P><V><T><V><Y><P><D><P><V><R><T><N><G><A><L><V><M><C><E><V><M><M><P><D><A><E><T><P><H><A><S><N><T><R><A><T><V><L><D><D><E><G><A><W><F><G...
Catalyzes the ATP-dependent biosynthesis of glutamine from glutamate and ammonia.<BOP>
P45626
Q31VE6
NIKE_SHIBS
Nickel import ATP-binding protein NikE
Shigella
<M><T><L><L><N><V><S><G><L><S><H><H><Y><A><H><G><G><F><S><G><K><H><Q><H><Q><A><V><L><N><N><V><S><L><T><L><K><S><G><E><T><V><A><L><L><G><R><S><G><C><G><K><S><T><L><A><R><L><L><V><G><L><E><S><P><S><Q><G><N><I><S><W><R><G><E><S><L><A><K><L><N><R><A><Q><R><K><A><F><R><R><D><I><Q><M><V><F><Q><D><S><I><S><A><V><N><P><R><K><T...
Part of the ABC transporter complex NikABCDE involved in nickel import. Responsible for energy coupling to the transport system.<BOP>
Q31VE6
O18924
PPARG_MACMU
Nuclear receptor subfamily 1 group C member 3
Macaca
<M><G><E><T><L><G><D><S><P><I><D><P><E><S><D><S><F><T><D><T><L><S><A><N><I><S><Q><E><I><T><M><V><D><T><E><M><P><F><W><P><T><N><F><G><I><S><S><V><D><L><S><V><M><D><D><H><S><H><S><F><D><I><K><P><F><T><T><V><D><F><S><S><I><S><A><P><H><Y><E><D><I><P><F><T><R><T><D><P><M><V><A><D><Y><K><Y><D><L><K><L><Q><E><Y><Q><S><A><I><K...
Nuclear receptor that binds peroxisome proliferators such as hypolipidemic drugs and fatty acids. Once activated by a ligand, the nuclear receptor binds to DNA specific PPAR response elements (PPRE) and modulates the transcription of its target genes, such as acyl-CoA oxidase. It therefore controls the peroxisomal beta...
O18924
Q99Z28
PYRDA_STRP1
Putative dihydroorotate dehydrogenase A (fumarate)
Streptococcus
<M><V><S><T><A><T><Q><I><G><H><F><S><F><D><N><C><L><M><N><A><A><G><V><Y><C><M><T><K><E><E><L><M><E><V><E><K><S><Q><A><A><S><F><V><T><K><T><G><T><L><E><V><R><P><G><N><P><E><P><R><Y><A><D><T><R><L><G><S><I><N><S><M><G><L><P><N><N><G><F><R><Y><Y><L><D><F><V><S><D><L><A><K><T><G><Q><H><K><P><H><F><L><S><V><V><G><L><S><P><T...
Catalyzes the conversion of dihydroorotate to orotate with fumarate as the electron acceptor.<BOP>
Q99Z28
A8GW65
ACPS_RICB8
4'-phosphopantetheinyl transferase AcpS
belli group
<M><I><I><G><V><G><T><D><I><V><Q><I><P><R><I><E><K><I><I><K><L><Y><P><E><I><F><P><K><R><I><L><N><T><E><E><L><K><K><F><A><L><L><K><K><E><S><H><V><T><F><L><A><K><R><F><A><A><K><E><A><I><S><K><A><F><G><V><G><I><G><R><G><I><N><F><K><D><I><T><L><L><N><D><E><L><G><K><P><I><V><K><I><D><S><L><Y><T><Q><K><L><P><P><F><N><I><H><L...
Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein.<BOP>
A8GW65
P93198
2SS_JUGRE
2S albumin seed storage protein large subunit
Juglans
<A><A><L><L><V><A><L><L><F><V><A><N><A><A><A><F><R><T><T><I><T><T><M><E><I><D><E><D><I><D><N><P><R><R><R><G><E><G><C><R><E><Q><I><Q><R><Q><Q><N><L><N><H><C><Q><Y><Y><L><R><Q><Q><S><R><S><G><G><Y><D><E><D><N><Q><R><Q><H><F><R><Q><C><C><Q><Q><L><S><Q><M><D><E><Q><C><Q><C><E><G><L><R><Q><V><V><R><R><Q><Q><Q><Q><Q><G><L><R...
Seed storage protein.<BOP>
P93198
P46017
FRAH_NOSS1
Protein FraH
Nostoc
<M><I><V><C><P><N><C><N><H><P><N><P><D><G><A><V><Q><C><E><A><C><Y><T><P><L><P><A><T><S><N><C><P><N><C><G><A><T><V><Q><S><D><A><A><F><C><G><Q><C><G><F><N><L><H><S><V><A><A><P><A><A><T><V><A><T><I><A><P><D><V><P><V><E><V><P><P><L><A><N><P><D><P><L><L><E><L><L><Q><P><N><A><L><G><L><D><P><V><A><N><E><N><P><P><A><P><A><P><L...
Putative heterocyst to vegetative cell connection.<BOP>
P46017
Q58HT5
AWAT1_HUMAN
Long-chain-alcohol O-fatty-acyltransferase 1
Homo
<M><A><H><S><K><Q><P><S><H><F><Q><S><L><M><L><L><Q><W><P><L><S><Y><L><A><I><F><W><I><L><Q><P><L><F><V><Y><L><L><F><T><S><L><W><P><L><P><V><L><Y><F><A><W><L><F><L><D><W><K><T><P><E><R><G><G><R><R><S><A><W><V><R><N><W><C><V><W><T><H><I><R><D><Y><F><P><I><T><I><L><K><T><K><D><L><S><P><E><H><N><Y><L><M><G><V><H><P><H><G><L...
Acyltransferase that catalyzes the formation of ester bonds between fatty alcohols and fatty acyl-CoAs to form wax monoesters . Shows a strong preference for decyl alcohol (C10), with less activity towards C16 and C18 alcohols . Shows a strong preference for saturated acyl-CoAs .<BOP>
Q58HT5
Q7VMD0
NDK_HAEDU
Nucleoside-2-P kinase
Haemophilus
<M><L><Q><Q><T><L><C><L><I><K><P><D><A><T><Q><R><N><L><I><G><K><I><I><S><Y><L><E><N><A><G><L><K><I><K><A><I><K><K><L><Q><L><T><Q><A><Q><A><E><K><F><Y><L><E><H><Q><D><K><P><F><F><A><S><L><V><G><F><M><I><S><A><P><I><V><A><I><V><L><E><G><E><N><A><I><A><H><Y><R><E><L><M><G><A><T><N><P><E><Q><R><E><A><G><T><I><R><A><L><Y><A...
Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.<BOP>
Q7VMD0
Q3AHX1
RPIA_SYNSC
Phosphoriboisomerase A
unclassified Synechococcus
<M><A><D><L><Q><T><Q><M><K><Q><A><V><A><D><A><A><V><E><Q><I><K><D><G><M><V><L><G><L><G><S><G><S><T><A><A><L><M><I><Q><G><L><G><A><K><L><A><S><G><E><L><K><D><I><V><G><V><T><T><S><F><Q><G><E><V><L><A><A><E><L><N><I><P><L><L><S><L><N><A><V><S><R><I><D><L><A><I><D><G><A><D><E><V><D><P><G><F><Q><L><I><K><G><G><G><A><C><H><V...
Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate.<BOP>
Q3AHX1
Q5PCK6
PXPA_SALPA
5-oxoprolinase (ATP-hydrolyzing) subunit A
Salmonella
<M><N><I><D><L><N><A><D><L><G><E><G><C><A><S><D><S><E><L><L><T><L><V><S><S><A><N><I><A><S><G><F><H><A><G><D><A><Q><T><M><L><T><C><V><R><E><A><L><K><N><G><V><A><I><G><A><H><P><S><F><P><D><R><D><N><F><G><R><T><A><M><V><L><P><P><E><T><V><Y><A><Q><T><L><Y><Q><I><G><A><L><G><A><I><V><Q><A><Q><G><G><V><M><R><H><V><K><P><H><G...
Catalyzes the cleavage of 5-oxoproline to form L-glutamate coupled to the hydrolysis of ATP to ADP and inorganic phosphate.<BOP>
Q5PCK6
Q5QW09
SYDP_IDILO
Protein Syd
Idiomarina
<M><K><T><L><E><E><S><I><D><A><L><M><T><R><Y><K><E><N><V><P><V><R><Y><T><E><Y><V><E><E><W><N><S><P><I><Y><G><T><V><I><D><E><N><T><V><E><W><T><P><C><R><Q><P><E><A><L><N><F><D><D><L><E><S><A><L><E><M><S><F><H><Q><S><I><K><T><L><F><G><R><W><Y><A><G><D><L><A><L><D><Y><Q><G><H><T><I><S><L><L><Q><T><Q><S><A><E><D><G><E><R><L...
Interacts with the SecY protein in vivo. May bind preferentially to an uncomplexed state of SecY, thus functioning either as a chelating agent for excess SecY in the cell or as a regulatory factor that negatively controls the translocase function.<BOP>
Q5QW09
Q4UMI6
RICKA_RICFE
Actin polymerization protein rickA
spotted fever group
<M><A><K><E><I><D><I><N><K><L><L><A><Q><E><N><N><A><L><N><T><I><L><S><Q><V><N><E><L><C><E><Q><N><K><K><L><Q><G><L><I><E><I><Q><N><E><T><K><E><L><E><K><E><H><N><R><S><L><P><W><F><K><R><L><V><K><T><V><S><N><V><K><Y><I><F><V><K><S><E><E><Q><L><T><N><E><A><I><K><Y><N><N><K><I><L><K><D><I><D><N><K><I><Y><N><I><A><E><K><S><A...
Recruits and activates the Arp2/3 complex, which in turn leads to actin polymerization, promoting Rickettsia motility during infection.<BOP>
Q4UMI6
Q4URG5
DSBB_XANC8
Disulfide oxidoreductase
Xanthomonas
<M><N><P><F><R><W><G><F><R><A><Q><F><L><L><G><F><L><A><C><A><G><L><L><A><Y><A><I><Y><V><Q><L><H><L><G><L><E><P><C><P><L><C><I><F><Q><R><I><A><F><A><T><L><A><L><L><F><L><L><G><A><L><H><G><P><R><G><A><G><G><R><K><A><Y><G><V><L><A><F><I><A><A><G><V><G><M><G><I><A><A><R><H><V><W><V><Q><I><R><P><K><D><M><M><S><S><C><G><P><P...
Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein.<BOP>
Q4URG5
C1DJD3
HIS6_AZOVD
ImGP synthase subunit HisF
Azotobacter
<M><A><L><A><K><R><I><I><P><C><L><D><V><D><N><G><R><V><V><K><G><V><R><F><E><N><I><R><D><A><G><D><P><V><E><I><A><Q><R><Y><D><E><Q><G><A><D><E><I><T><F><L><D><I><T><A><S><H><E><G><R><D><T><T><L><H><T><V><E><R><M><A><S><Q><V><F><I><P><L><T><V><G><G><G><V><R><T><V><Q><D><I><R><N><L><L><N><A><G><A><D><K><V><S><I><N><T><A><A...
IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.<BOP>
C1DJD3
Q252V9
RS3_CHLFF
30S ribosomal protein S3
Chlamydia
<M><G><Q><K><G><C><P><I><G><F><R><T><G><V><T><K><K><W><R><S><L><W><Y><G><N><K><Q><E><F><G><K><F><L><I><E><D><V><K><I><R><E><H><L><R><K><K><P><S><C><Q><G><A><A><G><F><V><V><R><R><M><S><G><K><I><E><V><T><I><Q><T><A><R><P><G><L><V><I><G><K><K><G><A><E><V><D><L><L><K><E><E><L><R><K><L><T><G><K><E><V><W><V><E><I><A><E><I><K...
Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation.<BOP>
Q252V9
E0SIS1
RHSIB_DICD3
Immunity protein RhsIB
Dickeya
<M><N><I><E><N><A><Y><D><Q><L><N><A><W><I><N><T><S><N><G><S><Y><I><D><I><G><G><E><R><Y><S><F><S><R><L><K><T><I><T><K><D><E><L><S><N><F><E><S><D><N><N><L><K><L><P><N><D><Y><K><S><F><L><I><N><V><G><C><V><N><I><F><V><G><E><K><T><A><G><I><E><I><I><P><P><T><D><I><R><N><F><S><K><S><V><F><Y><N><F><G><D><D><L><Y><P><R><L><L><L...
Immunity component of a toxin-immunity protein module, which functions as a cellular contact-dependent growth inhibition (CDI) system. Specifically inhibits its cognate toxin RhsB. Cell contact is necessary for growth inhibition.<BOP>
E0SIS1
Q3KLI3
RL6_CHLTA
50S ribosomal protein L6
Chlamydia
<M><S><R><K><A><R><D><P><I><V><L><P><Q><G><V><E><V><S><I><Q><N><D><E><I><S><V><K><G><P><K><G><S><L><T><Q><V><L><A><K><E><V><E><I><A><V><K><G><N><E><V><F><V><T><P><A><A><H><V><V><D><R><P><G><R><I><Q><G><L><Y><W><A><L><I><A><N><M><V><K><G><V><H><T><G><F><E><K><R><L><E><M><I><G><V><G><F><R><A><A><V><Q><G><S><L><L><D><L><S...
This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.<BOP>
Q3KLI3
Q2RIU8
IDI2_MOOTA
Type 2 isopentenyl diphosphate isomerase
Moorella
<M><N><E><R><E><Y><I><G><R><G><R><R><K><L><E><H><L><R><F><F><Q><E><D><S><K><G><S><N><G><L><E><D><V><H><L><V><H><Q><A><L><P><E><L><N><W><S><D><I><D><L><T><C><R><W><L><G><K><T><L><A><A><P><F><I><I><N><A><L><T><G><G><P><P><E><T><L><A><I><N><A><A><L><A><R><V><A><R><R><T><G><I><A><L><A><V><G><S><Q><R><A><G><L><E><N><K><E><W...
Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP).<BOP>
Q2RIU8
B2FMH7
AROE_STRMK
Shikimate dehydrogenase (NADP(+))
Stenotrophomonas maltophilia group
<M><T><D><R><Y><A><V><F><G><H><P><V><A><H><S><K><S><P><Q><I><H><A><T><F><G><R><Q><E><G><I><A><V><D><Y><R><A><I><D><L><A><P><E><A><F><L><A><G><L><E><A><F><A><A><D><G><G><V><G><A><N><V><T><S><P><H><K><E><A><A><F><S><V><C><T><T><L><T><A><R><A><R><R><A><G><S><V><N><T><L><L><R><K><G><D><R><W><H><G><D><T><T><D><G><I><G><L><V...
Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).<BOP>
B2FMH7
Q1BT81
LIPB_BURCA
Octanoyl-[acyl-carrier-protein]-protein N-octanoyltransferase
Burkholderia cepacia complex
<M><S><V><S><P><V><S><I><V><S><T><P><V><A><V><S><A><S><P><A><G><A><P><D><Q><P><V><Q><P><V><T><V><R><W><R><G><R><E><A><Y><E><A><S><F><D><A><M><R><A><F><T><D><T><R><T><A><D><T><G><D><E><I><W><V><V><E><H><P><P><V><Y><T><L><G><Q><A><G><D><P><A><H><L><L><V><A><D><S><G><V><P><L><V><K><V><D><R><G><G><Q><I><T><Y><H><G><P><G><Q...
Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate.<BOP>
Q1BT81
Q9LYT5
PME35_ARATH
Pectin methylesterase 35
Arabidopsis
<M><A><T><T><S><F><S><L><P><N><H><K><F><G><I><K><L><M><L><F><L><V><L><N><L><L><S><L><Q><T><S><V><F><A><H><S><S><N><S><K><F><T><K><I><S><R><H><P><N><S><D><S><S><S><R><T><K><P><S><T><S><S><N><K><G><F><L><S><S><V><Q><L><S><L><D><H><A><L><F><A><R><S><L><A><F><N><L><T><L><S><H><R><T><S><Q><T><L><M><L><D><P><V><N><D><C><L><E...
Acts in the modification of cell walls via demethylesterification of cell wall pectin.<BOP>
Q9LYT5
Q6C1W9
TRM10_YARLI
tRNA(m1G9)-methyltransferase
Yarrowia
<M><V><D><V><T><E><P><V><A><P><V><E><A><V><K><E><T><A><G><A><S><S><A><T><P><E><V><D><R><T><S><E><P><H><P><K><N><P><Q><N><V><P><A><P><Y><N><T><K><T><A><V><I><P><E><G><M><S><K><N><E><W><K><K><A><Q><K><K><A><I><W><E><S><K><K><D><E><I><A><A><V><K><K><E><K><K><K><A><A><R><K><R><K><Q><L><A><I><S><R><G><E><I><P><A><P><I><P><Q...
S-adenosyl-L-methionine-dependent guanine N(1)-methyltransferase that catalyzes the formation of N(1)-methylguanine at position 9 (m1G9) in cytoplasmic tRNA.<BOP>
Q6C1W9
Q4FQD6
DTD_PSYA2
Gly-tRNA(Ala) deacylase
Psychrobacter
<M><R><A><L><I><Q><R><V><K><H><A><S><V><S><V><D><G><H><D><V><G><A><I><E><H><G><V><L><A><Y><I><G><L><G><H><D><D><N><L><Q><S><A><Q><R><M><V><D><K><I><L><T><Y><R><I><F><E><N><D><D><D><P><A><K><Y><G><K><L><D><K><N><V><Q><Q><V><D><G><G><L><L><L><V><S><Q><F><T><L><M><A><K><T><D><K><G><R><R><P><D><F><G><G><A><M><A><P><D><A><A...
An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA-based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site. By rec...
Q4FQD6
B4SUV1
TUSD_SALNS
tRNA 2-thiouridine synthesizing protein D
Salmonella
<M><R><Y><A><I><M><V><T><G><A><A><Y><G><T><Q><Q><A><S><S><A><L><Q><F><A><H><A><L><L><N><E><G><H><E><L><A><S><V><F><F><Y><R><E><G><V><Y><N><A><N><L><L><T><S><P><A><S><D><E><Y><D><L><V><R><A><W><Q><K><L><N><T><Q><H><G><V><A><L><N><I><C><V><A><A><A><L><R><R><G><I><I><D><E><T><E><A><G><R><L><G><L><P><S><A><N><L><Q><P><G><F...
Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE.<BOP>
B4SUV1
Q7U4S9
NRDR_PARMW
Transcriptional repressor NrdR
Parasynechococcus marenigrum
<M><Q><C><P><S><Y><Q><N><T><D><S><R><V><L><E><S><R><A><A><D><G><G><R><S><V><R><R><R><R><E><C><L><N><C><E><F><R><F><T><T><Y><E><R><V><E><T><V><P><I><T><V><I><K><R><N><G><N><R><E><I><F><S><R><S><K><L><L><H><G><L><N><R><A><C><E><K><T><G><L><D><A><S><R><L><E><T><L><V><E><E><L><E><L><K><L><Q><Q><R><S><G><R><E><V><S><S><A><E...
Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes.<BOP>
Q7U4S9
C6DB84
Y1077_PECCP
Nucleoid-associated protein PC1_1077
Pectobacterium
<M><F><G><K><G><G><I><G><N><L><M><K><Q><A><Q><Q><M><Q><E><K><M><Q><Q><M><Q><E><E><V><A><N><L><E><V><T><G><E><S><G><A><G><L><V><K><I><T><I><N><G><A><H><N><C><R><R><V><E><I><D><P><S><L><M><E><D><D><K><E><M><L><E><D><L><I><A><A><A><F><N><D><A><A><R><R><I><A><E><T><Q><K><E><K><M><A><A><V><S><S><G><M><Q><L><P><P><G><F><K><M...
Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection.<BOP>
C6DB84
A6VR57
RS20_ACTSZ
30S ribosomal protein S20
Actinobacillus
<M><A><N><I><K><S><A><K><K><R><A><V><Q><S><E><K><R><R><Q><H><N><A><S><Q><R><S><M><M><R><T><Y><I><K><K><V><Y><A><A><V><A><A><G><E><K><S><A><A><Q><A><A><F><L><E><M><Q><K><V><V><D><R><M><A><S><K><G><L><I><H><A><N><K><A><A><N><H><K><S><K><L><S><A><Q><I><K><K><L><A>
Binds directly to 16S ribosomal RNA.<BOP>
A6VR57
Q6G3A4
SYP_BARHE
Prolyl-tRNA synthetase
Bartonella
<M><R><L><S><Q><Y><F><L><P><L><L><K><E><N><P><K><E><A><E><I><I><S><H><R><L><M><L><R><A><G><M><I><R><Q><Q><T><S><G><I><Y><S><W><L><P><L><G><K><K><V><L><D><K><I><C><K><I><I><R><E><E><Q><E><R><A><G><A><I><E><I><L><M><P><T><I><Q><S><A><D><L><W><R><E><S><D><R><Y><D><D><Y><G><L><E><M><L><R><I><K><D><R><Q><K><R><D><L><L><Y><G...
Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro).<BOP>
Q6G3A4
Q65ZT0
OTCC_BORGP
Ornithine carbamoyltransferase, catabolic
Borreliella
<M><Y><N><L><R><N><R><S><F><L><N><L><L><D><F><T><S><K><D><I><R><Y><L><L><D><L><S><I><D><L><K><K><S><K><Y><A><G><I><E><V><Q><K><L><K><G><K><N><M><A><I><I><F><E><K><D><S><T><R><T><R><C><A><F><E><I><A><A><Y><D><Q><G><A><N><I><T><Y><L><G><S><R><G><N><Q><I><G><V><K><E><S><M><M><D><T><A><R><V><L><G><R><M><Y><D><A><I><G><F><R...
Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline.<BOP>
Q65ZT0
B4T688
PAT_SALNS
Putrescine--2-oxoglutaric acid transaminase
Salmonella
<M><N><R><L><P><S><S><A><S><A><L><A><C><S><A><H><A><L><N><L><I><E><K><R><T><L><N><H><E><E><M><K><A><L><N><R><E><V><I><D><Y><F><K><E><H><V><N><P><G><F><L><E><Y><R><K><S><V><T><A><G><G><D><Y><G><A><V><E><W><Q><A><G><S><L><N><T><L><V><D><T><Q><G><Q><E><F><I><D><C><L><G><G><F><G><I><F><N><V><G><H><R><N><P><V><V><V><S><A><V...
Catalyzes the aminotransferase reaction from putrescine to 2-oxoglutarate, leading to glutamate and 4-aminobutanal, which spontaneously cyclizes to form 1-pyrroline. This is the first step in one of two pathways for putrescine degradation, where putrescine is converted into 4-aminobutanoate (gamma-aminobutyrate or GABA...
B4T688
A4J102
RL7_DESRM
50S ribosomal protein L7/L12
Desulforamulus
<M><S><K><V><A><E><V><L><E><I><V><K><G><L><T><V><L><E><L><A><E><L><V><K><A><F><E><E><E><F><G><V><S><A><A><A><P><V><A><V><A><A><A><P><A><A><G><A><A><A><A><E><E><E><K><T><E><F><D><V><I><L><T><S><A><G><D><K><K><I><N><V><I><K><V><V><R><E><I><T><G><L><G><L><K><E><A><K><E><L><V><D><G><A><P><K><P><V><K><E><K><I><A><K><E><E><A...
Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation.<BOP>
A4J102
Q54T57
PONM_DICDI
Ponticulin-like protein M
Dictyostelium
<M><K><F><L><S><T><L><I><L><L><L><S><V><L><A><L><V><R><G><E><Q><Y><N><K><F><T><V><D><L><N><G><V><C><T><N><S><G><S><L><D><T><C><T><N><Q><C><G><N><A><G><G><S><F><Q><I><S><Q><S><G><G><E><Y><Q><Y><E><Q><Y><A><T><K><D><C><D><L><M><A><S><L><T><S><K><F><A><C><L><A><D><E><A><P><V><T><L><G><L><G><N><I><K><I><T><C><Q><D><P><S><N...
Binds F-actin and nucleates actin assembly.<BOP>
Q54T57
A4WWP0
PNP_CERS5
Polynucleotide phosphorylase
Cereibacter
<M><F><N><V><T><K><K><S><I><E><W><G><G><E><T><L><T><L><E><T><G><K><V><A><R><Q><A><D><G><S><V><I><A><T><L><G><E><T><S><V><M><A><N><V><T><F><A><K><A><A><K><P><G><Q><D><F><F><P><L><T><V><H><Y><Q><E><R><Y><Y><A><A><G><K><V><P><G><G><F><F><K><R><E><A><R><P><S><E><K><E><T><L><T><S><R><L><I><D><R><P><I><R><P><L><F><V><D><G><F...
Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.<BOP>
A4WWP0
A9JX75
TOX1_PHANO
Toxin 1
Parastagonospora
<M><K><L><T><M><V><L><S><V><A><F><A><T><L><T><F><A><N><E><G><I><L><T><F><E><G><L><G><L><A><R><R><Q><T><I><C><H><T><P><G><G><S><G><C><R><A><S><I><S><G><D><Q><C><C><C><T><S><C><T><P><E><D><C><S><D><L><C><K><N><G><K><Q><A><A><H><E><A><Q><K><Q><K><K><C><A><K><C><C><N><A><G><G><E><S><H><E><L><C><C><S><I><A><S><A><G><I><D><C...
Necrotrophic effector that plays a critical role during fungal penetration, via its interaction with the host Snn1 protein . Snn1 is a member of the wall-associated kinase class of receptors, which are known to drive pathways for biotrophic pathogen resistance . Recognition of Tox1 by Snn1 induces mitogen-activated pro...
A9JX75
Q10YP7
PSTB_TRIEI
Phosphate-transporting ATPase
Trichodesmium
<M><L><E><H><Q><T><N><T><Y><Q><Q><N><S><T><P><A><L><S><A><E><N><L><S><I><F><Y><G><D><F><K><A><L><K><D><I><S><M><R><I><P><K><N><K><V><T><A><F><I><G><P><S><G><C><G><K><S><T><L><L><R><C><F><N><R><L><N><D><L><I><D><I><F><R><L><E><G><R><I><L><Y><H><N><Q><N><I><Y><D><P><D><I><D><P><V><E><I><R><R><H><I><G><M><V><F><Q><K><P><N...
Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system.<BOP>
Q10YP7
B5ZYC6
EX7L_RHILW
Exodeoxyribonuclease VII large subunit
Rhizobium
<M><S><N><V><F><D><S><D><S><P><T><N><L><A><E><Y><S><V><S><E><L><S><G><S><I><K><R><T><V><E><T><A><F><D><Q><V><R><V><R><G><E><I><S><G><Y><R><G><P><H><S><S><G><H><A><Y><F><A><L><K><D><D><R><A><R><I><D><A><V><I><W><K><G><T><F><S><R><L><K><F><R><P><E><E><G><M><E><V><I><A><T><G><K><V><T><T><F><P><G><S><S><K><Y><Q><I><V><I><E...
Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.<BOP>
B5ZYC6
Q8GYC7
PGL1B_ARATH
Ferredoxin-plastoquinone reductase 2
Arabidopsis
<M><A><F><T><L><T><I><P><R><F><S><A><I><S><R><K><P><I><T><C><S><S><S><R><T><Q><C><P><A><P><F><T><H><G><R><S><I><S><L><R><R><R><L><T><L><L><P><L><K><A><S><T><D><Q><S><G><Q><V><G><G><E><E><V><D><S><K><I><L><P><Y><C><S><I><N><K><N><E><K><R><T><I><G><E><M><E><Q><E><F><L><Q><A><M><Q><S><F><Y><Y><E><G><K><A><I><M><S><N><E><E...
Ferredoxin-plastoquinone reductase involved in cyclic electron flow (CEF) around photosystem I. The homodimer is probably not involved in CEF.<BOP>
Q8GYC7
Q1LLY7
HBOH_CUPMC
D-(-)-3-hydroxybutyrate oligomer hydrolase
Cupriavidus
<M><Q><Q><R><H><L><S><Q><S><A><H><S><H><G><H><G><T><R><R><A><H><R><R><N><T><I><A><I><A><V><A><T><L><A><V><A><A><C><G><G><F><G><T><N><G><S><G><G><N><T><G><P><N><V><K><P><A><F><I><S><G><P><V><G><V><K><S><Y><D><G><N><T><D><D><L><L><T><A><G><L><G><K><D><G><L><A><A><A><A><P><A><F><A><N><P><N><A><P><T><A><V><E><L><R><R><N><A...
Participates in the degradation of poly-3-hydroxybutyrate (PHB). It works downstream of poly(3-hydroxybutyrate) depolymerase, hydrolyzing D(-)-3-hydroxybutyrate oligomers of various length (3HB-oligomers) into 3HB-monomers.<BOP>
Q1LLY7
Q94JS0
UCRI1_ARATH
Ubiquinol-cytochrome c reductase iron-sulfur subunit 1
Arabidopsis
<M><L><R><V><A><G><R><R><L><F><S><V><S><Q><R><S><S><T><A><T><S><F><V><V><S><R><D><H><T><L><S><D><G><G><G><D><S><S><S><A><P><R><S><L><P><S><A><D><L><S><S><Y><H><R><S><L><I><R><G><F><S><S><Q><V><L><A><Q><G><N><E><I><G><F><G><S><E><V><P><A><T><V><E><A><V><K><T><P><N><S><K><I><V><Y><D><D><H><N><H><E><R><Y><P><P><G><D><P><S...
Component of the ubiquinol-cytochrome c oxidoreductase, a multisubunit transmembrane complex that is part of the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidor...
Q94JS0
P01942
HBA_MOUSE
Hemopressin
Mus
<M><V><L><S><G><E><D><K><S><N><I><K><A><A><W><G><K><I><G><G><H><G><A><E><Y><G><A><E><A><L><E><R><M><F><A><S><F><P><T><T><K><T><Y><F><P><H><F><D><V><S><H><G><S><A><Q><V><K><G><H><G><K><K><V><A><D><A><L><A><S><A><A><G><H><L><D><D><L><P><G><A><L><S><A><L><S><D><L><H><A><H><K><L><R><V><D><P><V><N><F><K><L><L><S><H><C><L><L...
Hemopressin acts as an antagonist peptide of the cannabinoid receptor CNR1. Hemopressin-binding efficiently blocks cannabinoid receptor CNR1 and subsequent signaling.<BOP>
P01942
P32340
NDI1_YEAST
NADH:ubiquinone reductase (non-electrogenic)
Saccharomyces
<M><L><S><K><N><L><Y><S><N><K><R><L><L><T><S><T><N><T><L><V><R><F><A><S><T><R><S><T><G><V><E><N><S><G><A><G><P><T><S><F><K><T><M><K><V><I><D><P><Q><H><S><D><K><P><N><V><L><I><L><G><S><G><W><G><A><I><S><F><L><K><H><I><D><T><K><K><Y><N><V><S><I><I><S><P><R><S><Y><F><L><F><T><P><L><L><P><S><A><P><V><G><T><V><D><E><K><S><I...
Catalyzes the oxidation of NADH generated inside the Mitochondrion.<BOP>
P32340
B2IMY9
SYE_STRPS
Glutamyl-tRNA synthetase
Streptococcus
<M><S><K><D><I><R><V><R><Y><A><P><S><P><T><G><V><V><H><I><G><N><A><R><T><A><L><F><N><Y><L><Y><A><R><H><H><G><G><T><F><L><I><R><I><E><D><T><D><R><K><R><H><V><E><D><G><E><R><S><Q><L><E><N><L><R><W><L><G><M><D><W><D><E><S><P><E><S><H><E><N><Y><R><Q><S><E><R><L><D><L><Y><Q><K><Y><I><D><Q><L><L><A><E><G><K><A><Y><K><S><Y><V...
Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).<BOP>
B2IMY9
Q6CF69
RLP24_YARLI
Ribosome biogenesis protein RLP24
Yarrowia
<M><R><V><Y><N><C><H><F><C><S><S><P><V><Y><P><G><K><G><I><M><F><V><R><N><D><S><K><E><F><R><F><C><R><S><K><C><H><K><N><F><K><M><K><R><N><P><R><K><L><R><W><T><K><A><F><R><K><A><A><G><K><E><M><V><V><D><S><T><L><A><F><S><A><R><R><D><V><P><V><R><Y><N><R><D><L><V><E><K><T><L><E><A><M><E><K><V><E><E><I><R><L><K><R><E><R><A><F...
Involved in the biogenesis of the 60S ribosomal subunit. Ensures the docking of YALI0_B00990g/NOG1 to pre-60S particles. Activates and recruits ATPase AFG2 to cytoplasmic pre-60S ribosomal particles.<BOP>
Q6CF69
Q57JA4
AAEB_SALCH
p-hydroxybenzoic acid efflux pump subunit AaeB
Salmonella
<M><G><I><F><S><I><A><N><Q><H><I><R><F><A><V><K><L><A><C><A><I><V><L><A><L><F><I><G><F><H><F><Q><L><E><T><P><R><W><A><V><L><T><A><A><I><V><A><A><G><P><A><F><A><A><G><G><E><P><Y><S><G><A><I><R><Y><R><G><M><L><R><I><I><G><T><F><I><G><C><I><A><A><L><I><I><I><I><S><M><I><R><A><P><L><L><M><I><L><V><C><C><V><W><A><G><F><C><T...
Forms an efflux pump with AaeA. Could function as a metabolic relief valve, allowing to eliminate certain compounds when they accumulate to high levels in the cell.<BOP>
Q57JA4
Q9S757
CYSC1_ARATH
O-acetylserine (thiol)-lyase 5
Arabidopsis
<M><A><S><V><S><R><R><L><L><R><R><E><T><I><P><C><F><S><H><T><V><R><K><L><F><S><T><V><G><S><P><S><F><A><Q><R><L><R><D><L><P><K><D><F><P><S><T><N><A><K><R><D><A><S><L><L><I><G><K><T><P><L><V><F><L><N><K><V><T><E><G><C><E><A><Y><V><A><A><K><Q><E><H><F><Q><P><T><C><S><I><K><D><R><P><A><I><A><M><I><A><D><A><E><K><K><K><L><I...
Acts as a major beta-cyanoalanine synthase. The cyanoalanine synthesis reaction is more efficient than the cysteine synthase activity. Probably unable to interact with SAT and to form the decameric Cys synthase complex (CSC) and is therefore not an enzymatically true OASTL protein. Probably involved in the detoxificati...
Q9S757
B0TEJ8
NADK_HELMI
ATP-dependent NAD kinase
Heliomicrobium
<M><P><T><V><G><V><V><L><N><D><D><K><P><Q><A><L><E><V><A><R><R><M><A><D><W><L><S><Q><R><E><V><P><M><G><I><P><L><T><R><V><A><E><L><V><H><S><P><S><P><E><L><R><D><R><L><R><Q><L><D><L><I><V><V><L><G><G><D><G><T><L><L><N><T><A><R><L><A><A><P><H><G><I><P><V><V><G><V><N><L><G><R><L><G><F><L><T><E><V><E><V><S><D><L><F><P><A><L...
Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.<BOP>
B0TEJ8
P08303
COXZ_PARDE
Cytochrome c oxidase assembly protein CtaG
Paracoccus
<M><S><G><G><K><P><R><S><N><T><R><T><V><A><M><L><A><G><V><V><V><L><M><G><A><L><S><W><A><A><V><P><F><Y><S><W><F><C><K><V><T><G><F><A><G><T><T><N><V><A><E><A><A><S><D><T><V><L><D><E><K><I><R><V><R><F><D><A><N><A><D><S><N><L><G><W><T><F><R><P><M><Q><R><E><M><E><L><K><I><G><E><N><A><I><A><F><Y><E><A><I><N><N><T><D><E><P><V...
Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I.<BOP>
P08303
P0A0M0
ETXH_STAAU
SEH
Staphylococcus
<M><I><N><K><I><K><I><L><F><S><F><L><A><L><L><L><S><F><T><S><Y><A><K><A><E><D><L><H><D><K><S><E><L><T><D><L><A><L><A><N><A><Y><G><Q><Y><N><H><P><F><I><K><E><N><I><K><S><D><E><I><S><G><E><K><D><L><I><F><R><N><Q><G><D><S><G><N><D><L><R><V><K><F><A><T><A><D><L><A><Q><K><F><K><N><K><N><V><D><I><Y><G><A><S><F><Y><Y><K><C><E...
Staphylococcal enterotoxin that activates the host immune system by binding as unprocessed molecules to major histocompatibility (MHC) complex class II and T-cell receptor (TCR) molecules via their alpha domain, in particular TRAV27 . In turn, this ternary complex activates a large number of T-lymphocytes initiating a ...
P0A0M0
A6WNV3
DAPE_SHEB8
N-succinyl-LL-2,6-diaminoheptanedioate amidohydrolase
Shewanella
<M><I><P><A><D><D><Y><P><V><T><E><L><T><K><A><L><I><A><R><P><S><V><T><P><L><D><E><G><C><Q><T><L><M><A><E><R><L><S><A><I><G><F><N><I><E><P><M><V><F><E><D><T><T><N><M><W><A><R><R><G><N><E><G><P><V><F><C><F><A><G><H><T><D><V><V><P><T><G><D><V><S><R><W><H><T><P><P><F><V><P><T><I><I><D><G><Y><L><Y><G><R><G><A><A><D><M><K><G...
Catalyzes the hydrolysis of N-succinyl-L,L-diaminopimelic acid (SDAP), forming succinate and LL-2,6-diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls.<BOP>
A6WNV3
B8EBJ4
RL24_SHEB2
50S ribosomal protein L24
Shewanella
<M><A><A><K><I><R><R><E><D><E><V><I><V><L><A><G><K><D><K><G><K><R><A><K><V><S><Q><V><L><P><T><G><K><L><I><V><E><G><I><N><L><V><K><K><H><Q><K><P><N><P><Q><L><G><V><A><G><G><I><V><E><K><E><A><P><I><Q><A><S><N><V><A><I><F><N><S><A><T><G><K><A><D><R><V><G><F><R><F><E><D><G><K><K><V><R><F><F><K><S><N><S><E><L><V><K>
One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.<BOP>
B8EBJ4
A9JRZ0
SMUF2_DANRE
SMAD-specific E3 ubiquitin-protein ligase 2
Danio
<M><S><N><Q><G><V><R><R><N><G><P><V><K><L><R><L><T><V><L><C><A><K><N><L><V><K><K><D><F><F><R><L><P><D><P><F><A><K><V><V><V><D><G><S><G><Q><C><H><S><T><D><T><V><R><N><T><L><D><P><K><W><N><Q><H><Y><D><L><Y><I><G><K><S><D><S><I><T><I><S><V><W><N><H><K><K><I><H><K><K><Q><G><A><G><F><L><G><C><V><R><L><L><S><N><S><I><N><R><L...
E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates.<BOP>
A9JRZ0
Q9JYJ8
PYRG_NEIMB
UTP--ammonia ligase
Neisseria
<M><T><K><F><I><F><V><T><G><G><V><V><S><S><L><G><K><G><I><A><A><A><S><I><A><A><I><L><E><S><R><G><L><N><V><T><M><L><K><L><D><P><Y><I><N><V><D><P><G><T><M><S><P><F><Q><H><G><E><V><F><V><T><D><D><G><A><E><T><D><L><D><L><G><H><Y><E><R><F><I><D><S><T><M><T><R><R><N><S><F><S><T><G><Q><V><Y><E><N><V><I><A><K><E><R><R><G><D><Y...
Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.<BOP>
Q9JYJ8
Q1H1Z8
CRCB_METFK
Putative fluoride ion transporter CrcB
Methylobacillus
<M><Y><Q><V><M><L><V><A><L><G><G><A><I><G><S><A><A><R><F><T><L><S><G><L><V><L><R><Y><S><L><D><W><R><F><P><L><P><T><F><T><V><N><I><I><G><C><L><V><I><G><M><L><A><G><L><A><S><K><E><G><F><I><S><P><D><M><R><V><L><L><F><T><G><L><V><G><G><F><T><T><F><S><A><F><G><L><E><T><L><V><L><L><R><E><G><L><V><G><I><A><A><A><Y><I><V><S><S...
Important for reducing fluoride concentration in the cell, thus reducing its toxicity.<BOP>
Q1H1Z8
Q2RLU8
UVRC_MOOTA
Excinuclease ABC subunit C
Moorella
<M><D><L><E><E><K><L><A><R><L><P><D><H><P><G><V><Y><I><M><H><D><A><N><G><A><I><I><Y><V><G><K><A><A><S><L><R><N><R><V><R><S><Y><F><R><G><Q><H><Q><P><R><T><Q><A><M><V><S><H><V><A><D><F><E><Y><I><L><T><D><N><E><V><E><A><L><I><L><E><C><N><L><I><K><Q><H><R><P><R><Y><N><V><S><L><K><D><D><K><S><Y><P><Y><I><K><I><T><T><Q><E><D...
The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.<BOP>
Q2RLU8
P52894
ALA2_HORVU
Glutamic--pyruvic transaminase 2
Hordeum
<M><A><A><T><V><A><V><D><N><L><N><P><K><V><L><K><C><E><Y><A><V><R><G><E><I><V><I><H><A><Q><R><L><Q><E><Q><L><K><T><Q><P><G><S><L><P><F><D><E><I><L><Y><C><N><I><G><N><P><Q><S><L><G><Q><Q><P><V><T><F><F><R><E><V><L><A><L><C><D><H><P><D><L><L><Q><R><E><E><I><K><T><L><F><S><A><D><S><I><S><R><A><K><Q><I><L><A><M><I><P><G><R...
Transfer of C3 units between the cytosol of mesophyll and bundle sheath cells to maintain a nitrogen-carbon balance in the C4-dicarboxylic pathway.<BOP>
P52894
Q882V6
MOAA_PSESM
Molybdenum cofactor biosynthesis protein A
Pseudomonas
<M><S><E><P><V><L><M><D><R><F><A><R><K><V><D><Y><L><R><M><S><V><T><D><R><C><D><F><R><C><V><Y><C><M><A><E><E><M><T><F><L><P><R><Q><Q><I><L><S><L><E><E><I><H><Q><V><A><E><R><F><V><A><L><G><T><R><K><I><R><L><T><G><G><E><P><L><V><R><A><G><V><V><G><L><C><E><K><I><A><A><L><P><G><L><R><E><L><C><M><T><T><N><G><S><Q><L><D><K><L...
Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate.<BOP>
Q882V6
B1IIG7
SYE_CLOBK
Glutamyl-tRNA synthetase
Clostridium
<M><T><N><K><V><R><T><R><F><A><P><S><P><T><G><Y><M><H><V><G><N><L><R><T><A><L><Y><A><Y><L><I><A><K><H><D><N><G><D><F><I><L><R><I><E><D><T><D><Q><E><R><L><V><E><G><A><L><D><V><I><Y><N><T><L><K><I><T><G><L><S><H><D><E><G><P><D><I><G><G><P><V><G><P><Y><V><Q><S><E><R><R><N><I><Y><I><E><Y><A><E><K><L><I><E><K><G><E><A><Y><Y...
Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).<BOP>
B1IIG7
A6Q4N8
GUAA_NITSB
Glutamine amidotransferase
unclassified Nitratiruptor
<M><Q><E><V><P><I><V><I><L><D><F><G><S><Q><Y><T><Q><L><I><A><R><R><L><R><E><V><G><V><Y><C><E><I><Y><P><F><F><E><P><I><E><N><I><R><A><K><K><P><Q><G><I><I><L><S><G><G><P><A><S><V><Y><E><P><D><A><P><R><V><D><K><A><I><Y><E><L><G><I><P><V><L><G><I><C><Y><G><M><Q><L><I><T><V><D><F><G><G><Q><V><V><R><A><L><E><H><E><Y><G><K><A...
Catalyzes the synthesis of GMP from XMP.<BOP>
A6Q4N8
A0LXV8
NADK_GRAFK
ATP-dependent NAD kinase
Gramella
<M><K><I><G><I><Y><G><Q><F><Y><H><A><N><A><A><Q><Y><I><G><Q><L><L><E><L><L><D><Q><R><N><I><E><V><L><I><E><E><D><F><L><K><L><I><H><S><N><N><K><I><E><K><D><Y><K><H><F><S><A><F><E><E><L><D><N><S><F><D><L><F><F><C><I><G><G><D><G><T><I><L><K><S><I><N><Y><I><R><N><L><D><I><P><I><V><G><I><N><T><G><R><L><G><F><L><A><T><I><Q><K...
Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.<BOP>
A0LXV8
Q9KGJ6
GLMU_HALH5
Glucosamine-1-phosphate N-acetyltransferase
Halalkalibacterium (ex Joshi et al. 2022)
<M><S><N><R><F><A><V><I><L><A><A><G><Q><G><T><R><M><K><S><K><L><Y><K><V><L><H><S><V><C><G><K><P><M><V><Q><H><V><V><D><Q><V><S><A><L><G><F><D><E><I><V><T><I><I><G><H><G><A><D><A><V><K><S><Q><L><G><E><R><V><S><Y><A><L><Q><E><E><Q><L><G><T><G><H><A><V><L><Q><A><E><S><A><L><G><G><R><R><G><V><T><I><V><L><C><G><D><T><P><L><L...
Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted ...
Q9KGJ6
Q1RH25
TGT_RICBR
tRNA-guanine transglycosylase
belli group
<M><S><K><F><S><F><N><I><N><H><Q><Y><K><K><A><R><S><G><I><I><T><T><A><H><G><N><I><R><T><P><A><F><M><P><V><G><T><R><G><T><V><K><A><M><L><P><E><S><V><A><E><T><G><A><D><I><L><L><G><N><T><Y><H><L><M><L><Q><P><S><A><E><R><I><A><K><L><G><G><L><H><K><F><M><N><W><G><K><P><I><L><T><D><S><G><G><F><Q><V><M><S><L><S><K><L><R><K><I...
Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks th...
Q1RH25
Q9W4C5
NAAT1_DROME
Sodium-dependent nutrient amino acid transporter 1
Sophophora
<M><E><L><K><G><V><Q><P><S><N><G><S><S><N><G><S><G><N><G><A><T><N><A><A><S><T><E><K><T><D><A><E><K><P><T><A><E><R><T><N><W><G><N><G><L><E><F><L><M><S><C><I><S><V><S><V><G><L><G><N><V><W><R><F><P><F><T><A><Y><E><N><G><G><G><A><F><L><I><P><Y><I><I><V><L><F><L><I><G><K><P><M><Y><Y><L><E><M><I><M><G><Q><F><T><S><Q><G><T><V...
Unusual broad substrate spectrum amino acid:sodium cotransporter that promotes absorption of the D isomers of essential amino acids. Neutral amino acids are the preferred substrates, especially methionine and phenylalanine.<BOP>
Q9W4C5
P62452
HIS6_PHOPR
ImGP synthase subunit HisF
Photobacterium
<M><L><A><K><R><I><V><P><C><L><D><V><R><D><G><Q><V><V><K><G><V><Q><F><R><N><H><E><I><I><G><D><I><V><P><L><A><K><R><Y><A><E><E><G><A><D><E><L><V><F><Y><D><I><T><A><S><S><D><G><R><V><V><D><K><S><W><V><A><R><V><A><E><V><I><D><I><P><F><C><V><A><G><G><I><K><S><V><E><D><A><S><R><I><L><Q><F><G><A><D><K><V><S><I><N><S><P><A><L...
IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.<BOP>
P62452
Q3B3Q8
G6PI_CHLL3
Phosphohexose isomerase
Pelodictyon
<M><D><L><S><R><S><A><A><W><S><A><L><V><S><H><R><Q><E><V><E><Q><L><H><M><R><D><M><F><M><S><D><H><D><R><F><K><H><F><S><I><R><W><N><G><L><L><L><D><Y><S><K><N><R><I><N><S><R><T><M><G><L><L><V><E><L><A><R><Q><A><N><L><I><E><A><R><D><G><M><F><A><G><E><K><I><N><F><T><E><N><R><A><V><L><H><T><A><L><R><R><Q><P><G><Y><T><L><N><V...
Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.<BOP>
Q3B3Q8
A4WIW5
SYT_PYRAR
Threonyl-tRNA synthetase
Pyrobaculum
<M><R><V><L><Y><I><H><A><E><R><F><S><W><D><P><R><D><P><A><L><D><I><R><D><E><P><V><S><G><S><A><S><N><A><L><V><V><F><V><S><V><E><R><G><D><S><P><D><E><G><F><L><K><A><V><A><A><D><V><V><E><T><A><K><K><V><G><A><S><S><I><V><V><Y><P><Y><A><H><L><S><T><D><L><A><R><P><Y><T><A><R><E><V><V><G><K><L><Y><E><V><V><K><A><Q><F><K><G><Q...
Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction: L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr). Also edits incorrectly charged L-seryl-tRNA(Thr).<BOP>
A4WIW5
Q1BUV6
MSBA_BURCA
Lipid A export ATP-binding/permease protein MsbA
Burkholderia cepacia complex
<M><E><T><Q><N><T><L><R><K><P><M><D><G><T><G><T><S><P><M><T><V><L><K><R><L><W><P><Y><I><R><P><L><I><G><I><V><V><L><A><V><V><T><M><G><V><V><A><A><T><E><A><G><I><P><A><L><L><K><P><L><L><D><H><G><F><G><S><H><G><S><D><S><A><K><W><Y><V><P><I><A><V><I><G><L><A><L><V><R><G><V><S><Q><Y><T><S><N><Y><L><L><N><Y><V><S><N><R><I><L...
Involved in lipopolysaccharide (LPS) biosynthesis. Translocates lipid A-core from the inner to the outer leaflet of the inner membrane. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation.<BOP>
Q1BUV6
P41271
NBL1_HUMAN
Zinc finger protein DAN
Homo
<M><M><L><R><V><L><V><G><A><V><L><P><A><M><L><L><A><A><P><P><P><I><N><K><L><A><L><F><P><D><K><S><A><W><C><E><A><K><N><I><T><Q><I><V><G><H><S><G><C><E><A><K><S><I><Q><N><R><A><C><L><G><Q><C><F><S><Y><S><V><P><N><T><F><P><Q><S><T><E><S><L><V><H><C><D><S><C><M><P><A><Q><S><M><W><E><I><V><T><L><E><C><P><G><H><E><E><V><P><R...
Possible candidate as a tumor suppressor gene of neuroblastoma. May play an important role in preventing cells from entering the final stage (G1/S) of the transformation process.<BOP>
P41271
O77061
MRJP2_APIME
Bee-milk protein
Apis
<M><T><R><W><L><F><M><V><A><C><L><G><I><A><C><Q><G><A><I><V><R><E><N><S><P><R><N><L><E><K><S><L><N><V><I><H><E><W><K><Y><F><D><Y><D><F><G><S><E><E><R><R><Q><A><A><I><Q><S><G><E><Y><D><H><T><K><N><Y><P><F><D><V><D><Q><W><R><D><K><T><F><V><T><I><L><R><Y><D><G><V><P><S><T><L><N><V><I><S><G><K><T><G><K><G><G><R><L><L><K><P...
May play an important role in honeybee nutrition. It is found in the royal jelly which is the food of the queen honey bee larva. The royal jelly determines the development of the young larvae and is responsible for the high reproductive ability of the honeybee queen.<BOP>
O77061
Q31Y50
PTYBC_SHIBS
PTS system N-acetylmuramic acid-specific EIIC component
Shigella
<M><A><K><E><I><S><S><E><L><L><N><T><I><L><T><R><V><G><G><P><G><N><I><A><S><C><G><N><C><M><T><R><L><R><L><G><V><H><D><S><S><L><V><D><P><N><I><K><T><L><E><G><V><K><S><V><I><L><T><S><D><Q><V><Q><V><V><F><G><P><G><K><A><H><R><A><A><K><A><M><S><E><L><L><G><E><A><P><V><Q><D><A><A><E><I><A><A><Q><N><K><R><Q><L><K><A><K><Q><T...
The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. This system is involved in N-acetylmuramic acid (MurNAc) transport, yie...
Q31Y50
P61316
LOLA_ECOLI
P20
Escherichia
<M><K><K><I><A><I><T><C><A><L><L><S><S><L><V><A><S><S><V><W><A><D><A><A><S><D><L><K><S><R><L><D><K><V><S><S><F><H><A><S><F><T><Q><K><V><T><D><G><S><G><A><A><V><Q><E><G><Q><G><D><L><W><V><K><R><P><N><L><F><N><W><H><M><T><Q><P><D><E><S><I><L><V><S><D><G><K><T><L><W><F><Y><N><P><F><V><E><Q><A><T><A><T><W><L><K><D><A><T><G...
May act as a regulator of the RCS-phosphorelay signal transduction pathway.<BOP>
P61316
P38837
NSG1_YEAST
INSIG homolog 1
Saccharomyces
<M><G><K><K><K><S><K><N><Q><L><N><T><G><G><V><P><N><G><V><H><N><T><K><K><E><A><A><L><P><P><L><G><N><K><L><G><S><A><S><F><T><A><I><N><T><L><T><K><P><A><L><F><S><F><Y><D><D><D><I><T><K><N><E><G><N><V><Y><D><K><A><L><L><S><N><A><S><Q><L><E><M><V><P><P><S><A><T><A><R><H><E><R><S><L><Y><A><K><I><I><N><T><I><A><A><F><F><I><L...
Stabilizes the HMG-CoA reductase HMG2 by preventing its HRD1-dependent degradation. Binds directly to the sterol-sensing domain (SSD)-containing transmembrane region of HMG2, promoting its folding to protect it from degradation.<BOP>
P38837
Q14CS0
UBX2B_HUMAN
p97 cofactor p37
Homo
<M><A><E><G><G><G><P><E><P><G><E><Q><E><R><R><S><S><G><P><R><P><P><S><A><R><D><L><Q><L><A><L><A><E><L><Y><E><D><E><V><K><C><K><S><S><K><S><N><R><P><K><A><T><V><F><K><S><P><R><T><P><P><Q><R><F><Y><S><S><E><H><E><Y><S><G><L><N><I><V><R><P><S><T><G><K><I><V><N><E><L><F><K><E><A><R><E><H><G><A><V><P><L><N><E><A><T><R><A><S...
Adapter protein required for Golgi and endoplasmic reticulum biogenesis . Involved in Golgi and endoplasmic reticulum maintenance during interphase and in their reassembly at the end of mitosis . The complex formed with VCP has membrane fusion activity; membrane fusion activity requires USO1-GOLGA2 tethering and BET1L ...
Q14CS0
Q4JTZ6
RS18_CORJK
30S ribosomal protein S18
Corynebacterium
<M><K><R><T><N><M><K><K><A><R><M><E><Q><S><R><R><P><K><K><N><P><L><K><A><E><G><I><E><T><V><D><Y><K><N><Y><D><L><L><R><K><F><I><S><E><R><G><K><I><R><S><R><R><V><T><G><L><T><P><Q><Q><Q><R><Q><V><A><T><A><V><K><N><A><R><E><M><A><L><L><P><F><H><S><R>
Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.<BOP>
Q4JTZ6
Q9PQI5
END4_UREPA
Endonuclease IV
Ureaplasma
<M><D><K><Y><N><L><I><I><G><S><H><V><S><L><K><A><K><D><F><F><Y><G><S><V><K><E><A><L><S><Y><G><S><N><T><F><M><V><Y><T><G><A><P><Q><N><T><K><R><Q><P><I><K><S><F><K><I><E><E><A><H><N><L><L><K><K><H><N><I><N><L><D><D><L><I><V><H><A><P><Y><I><I><N><P><C><S><S><K><K><N><V><R><E><L><A><K><E><F><L><I><Q><E><I><Q><R><T><E><S><M...
Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic (AP) sites, generating a 3'-hydroxyl group and a 5'-terminal sugar phosphate.<BOP>
Q9PQI5
P04969
RS11_BACSU
30S ribosomal protein S11
Bacillus
<M><A><A><A><R><K><S><N><T><R><K><R><R><V><K><K><N><I><E><S><G><I><A><H><I><R><S><T><F><N><N><T><I><V><T><I><T><D><T><H><G><N><A><I><S><W><S><S><A><G><A><L><G><F><R><G><S><R><K><S><T><P><F><A><A><Q><M><A><A><E><T><A><A><K><G><S><I><E><H><G><L><K><T><L><E><V><T><V><K><G><P><G><S><G><R><E><A><A><I><R><A><L><Q><A><A><G><L...
Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome.<BOP>
P04969
C6DIA0
PAGP_PECCP
Lipid A acylation protein
Pectobacterium
<M><Y><L><K><R><T><L><I><T><L><S><L><I><T><L><P><I><V><P><F><L><S><Y><A><A><E><S><I><N><N><T><S><S><T><E><N><L><A><P><V><T><V><D><S><S><D><P><V><S><D><K><Q><G><E><S><W><W><Q><R><S><K><N><N><L><S><T><T><W><N><A><P><Q><S><H><D><I><Y><I><P><A><I><T><W><H><N><R><W><T><Y><D><K><E><K><T><D><R><Y><N><E><R><P><W><G><A><G><Y><G...
Transfers a palmitate residue from the sn-1 position of a phospholipid to the N-linked hydroxymyristate on the proximal unit of lipid A or its precursors.<BOP>
C6DIA0
P57776
EF1D_MOUSE
Elongation factor 1-delta
Mus
<M><A><T><N><F><L><A><H><E><K><I><W><F><D><K><F><K><Y><D><D><A><E><R><R><F><Y><E><Q><M><N><G><P><V><T><S><G><S><R><Q><E><N><G><A><S><V><I><L><R><D><I><A><R><A><R><E><N><I><Q><K><S><L><A><G><S><S><G><P><G><A><S><S><G><P><G><G><D><H><S><E><L><I><V><R><I><T><S><L><E><V><E><N><Q><N><L><R><G><V><V><Q><D><L><Q><Q><A><I><S><K...
Regulates induction of heat-shock-responsive genes through association with heat shock transcription factors and direct DNA-binding at heat shock promoter elements (HSE).<BOP>
P57776
A9LYY9
PROA_NEIM0
Glutamyl-gamma-semialdehyde dehydrogenase
Neisseria
<M><S><N><T><Q><K><Q><L><A><L><A><K><A><A><K><K><S><V><N><T><A><D><T><E><E><K><N><R><A><L><L><A><M><A><D><S><L><E><A><A><A><A><D><I><L><A><A><N><R><Q><D><L><E><A><A><A><G><N><I><P><E><S><M><T><D><R><L><L><L><D><G><K><R><I><C><A><M><A><D><G><I><R><A><V><A><A><L><P><D><P><V><G><E><I><L><E><T><S><T><L><P><N><G><L><E><I><V...
Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate.<BOP>
A9LYY9
A1A1K1
RUVC_BIFAA
Holliday junction resolvase RuvC
Bifidobacterium
<M><I><I><L><G><V><D><P><G><L><T><R><C><G><V><G><V><I><E><A><G><A><Y><R><R><L><S><F><I><H><V><D><V><V><R><S><D><P><K><T><S><Q><D><L><R><L><L><A><I><Y><N><G><L><V><E><K><I><E><R><F><A><P><D><A><V><S><I><E><R><V><F><A><Q><E><N><R><N><T><V><L><G><T><A><Q><A><A><G><L><A><M><L><A><A><A><Q><R><G><I><P><V><A><L><H><T><P><T><E...
Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group.<BOP>
A1A1K1
Q93CX7
UPP_LATSK
UPRTase
Latilactobacillus
<M><A><K><F><T><V><L><N><H><P><L><I><Q><H><K><L><T><I><I><R><N><K><N><T><G><T><K><V><F><R><E><V><A><N><E><I><A><E><L><M><V><Y><E><I><T><R><D><L><A><M><E><D><V><E><V><E><T><P><M><G><P><A><I><E><K><Q><L><S><G><K><K><L><A><V><V><P><I><L><R><A><G><L><G><M><V><D><G><V><L><E><L><I><P><A><A><K><V><G><H><I><G><M><Y><R><D><E><K...
Catalyzes the conversion of uracil and 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to UMP and diphosphate.<BOP>
Q93CX7
C1DI51
PYRE_AZOVD
Orotate phosphoribosyltransferase
Azotobacter
<M><Q><A><Y><Q><R><E><F><I><R><F><A><I><E><R><G><V><L><R><F><G><E><F><T><L><K><S><G><R><T><S><P><Y><F><F><N><A><G><L><F><D><S><G><L><A><L><A><R><L><G><R><F><Y><A><S><A><L><V><G><S><G><I><A><F><D><V><L><F><G><P><A><Y><K><G><I><P><L><A><A><A><T><A><V><A><L><A><E><H><H><G><L><D><L><P><W><C><F><N><R><K><E><A><K><D><H><G><E...
Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).<BOP>
C1DI51
Q9H0B6
KLC2_HUMAN
Kinesin light chain 2
Homo
<M><A><M><M><V><F><P><R><E><E><K><L><S><Q><D><E><I><V><L><G><T><K><A><V><I><Q><G><L><E><T><L><R><G><E><H><R><A><L><L><A><P><L><V><A><P><E><A><G><E><A><E><P><G><S><Q><E><R><C><I><L><L><R><R><S><L><E><A><I><E><L><G><L><G><E><A><Q><V><I><L><A><L><S><S><H><L><G><A><V><E><S><E><K><Q><K><L><R><A><Q><V><R><R><L><V><Q><E><N><Q...
Kinesin is a microtubule-associated force-producing protein that plays a role in organelle transport. The light chain functions in coupling of cargo to the heavy chain or in the modulation of its ATPase activity (Probable). Through binding with PLEKHM2 and ARL8B, recruits kinesin-1 to lysosomes and hence direct lysosom...
Q9H0B6
Q0TRK5
COBT_CLOP1
N(1)-alpha-phosphoribosyltransferase
Clostridium
<M><L><N><E><V><L><K><G><I><E><G><L><D><N><D><M><I><L><K><A><K><N><R><V><D><S><L><A><K><P><L><G><S><L><G><K><L><E><D><I><A><I><R><L><S><G><I><T><G><N><M><F><N><N><I><D><K><K><C><V><I><I><M><S><S><D><N><G><V><E><E><E><G><V><A><S><A><P><Q><C><V><T><L><L><Q><T><K><N><F><I><K><G><T><T><G><V><A><T><L><A><K><S><N><G><T><D><L...
Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6-dimethylbenzimidazole (DMB).<BOP>
Q0TRK5