accession stringlengths 6 10 | name stringlengths 6 11 | Full Name stringlengths 1 147 ⌀ | taxon stringlengths 3 46 ⌀ | sequence stringlengths 48 2.3k | function stringlengths 11 1.34k | AlphaFoldDB stringlengths 6 10 |
|---|---|---|---|---|---|---|
Q8KBZ7 | HPRK_CHLTE | HPr(Ser) kinase/phosphorylase | Chlorobaculum | <M><N><F><D><Q><K><G><L><K><K><R><S><I><T><V><A><Y><F><F><E><H><I><Q><K><R><F><D><I><K><F><R><R><L><N><E><L><D><E><Q><K><C><R><I><H><E><R><D><L><H><R><P><G><L><A><I><A><G><F><T><K><L><F><T><Y><K><R><V><Q><I><L><G><N><T><E><T><R><Y><L><N><H><L><S><D><E><E><R><K><T><A><F><A><N><F><V><S><F><R><M><P><C><I><I><L><T><S><N><N... | Catalyzes the ATP- as well as the pyrophosphate-dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK/P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphor... | Q8KBZ7 |
A9BMV7 | NDK_DELAS | Nucleoside-2-P kinase | Delftia | <M><A><I><E><R><T><L><S><I><I><K><P><D><A><V><A><K><N><V><I><G><Q><I><Y><A><R><F><E><G><A><G><L><K><V><I><A><A><K><M><V><H><L><S><R><G><E><A><E><Q><F><Y><G><V><H><K><E><R><P><F><F><K><D><L><V><D><F><M><V><S><G><P><V><M><I><Q><A><L><E><G><E><N><A><I><L><K><N><R><E><L><M><G><A><T><D><P><K><K><A><E><K><G><T><I><R><A><D><F... | Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.<BOP> | A9BMV7 |
A6LF29 | ISPF_PARD8 | 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase | Parabacteroides | <M><K><I><R><V><G><F><G><Y><D><V><H><A><L><V><P><D><R><E><L><W><L><G><G><I><K><I><E><H><T><L><G><L><L><G><H><S><D><A><D><V><L><I><H><A><I><C><D><A><L><L><G><A><A><N><M><R><D><I><G><Y><H><F><P><D><T><A><G><E><Y><K><N><I><D><S><K><I><L><L><R><D><T><M><R><L><L><R><E><A><G><Y><E><L><G><N><I><D><A><T><V><A><A><E><R><P><K><L... | Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a correspond... | A6LF29 |
Q8DPV9 | AGGDS_STRR6 | Alpha-galactosylglucosyldiacylglycerol synthase | Streptococcus | <M><R><K><F><P><L><F><S><S><S><L><S><F><L><L><L><I><L><F><K><E><N><D><I><I><V><V><M><E><K><K><K><L><R><I><N><M><L><S><S><S><E><K><V><A><G><Q><G><V><S><G><A><Y><R><E><L><V><R><L><L><H><R><A><A><K><D><Q><L><I><V><T><E><N><L><P><I><E><A><D><V><T><H><F><H><T><I><D><F><P><Y><Y><L><S><T><F><Q><K><K><R><S><G><R><K><I><G><Y><V... | Galactosyltransferase involved in the biosynthesis of the bilayer-forming membrane lipid alpha-galactosyl-glucosyldiacylglycerol which is involved in maintaining constant nonbilayer/bilayer conditions (curvature packing stress). Also involved in the beta-lactam resistance. Catalyzes the transfer of a galactosyl residue... | Q8DPV9 |
A3N3Q5 | SLMA_ACTP2 | Nucleoid occlusion factor SlmA | Actinobacillus | <M><I><Q><P><T><V><K><M><P><K><K><S><V><K><E><R><Q><Q><Q><V><L><E><V><L><I><G><L><L><N><S><E><D><G><M><Q><R><V><T><T><E><R><L><A><K><A><V><G><V><S><E><G><A><L><Y><R><Y><F><P><S><K><T><K><M><F><E><A><L><I><E><R><I><E><Q><T><L><T><G><Y><I><N><A><S><K><R><K><E><N><T><T><A><S><T><V><K><A><I><L><Y><T><V><I><E><F><A><R><K><N... | Required for nucleoid occlusion (NO) phenomenon, which prevents Z-ring formation and cell division over the nucleoid. Acts as a DNA-associated cell division inhibitor that binds simultaneously chromosomal DNA and FtsZ, and disrupts the assembly of FtsZ polymers. SlmA-DNA-binding sequences (SBS) are dispersed on non-Ter... | A3N3Q5 |
Q8KAJ0 | RL15_CHLTE | 50S ribosomal protein L15 | Chlorobaculum | <M><D><L><S><S><L><R><P><A><K><G><A><V><K><A><R><K><R><V><G><R><G><P><G><S><G><N><G><T><T><A><G><K><G><N><K><G><Q><Q><S><R><S><G><Y><Q><R><P><V><I><E><G><G><Q><M><P><I><Y><R><R><L><P><K><F><G><F><T><P><P><N><Q><K><A><V><A><C><V><N><V><A><Q><I><Q><M><W><I><E><K><G><L><V><G><E><E><I><S><V><L><D><L><K><H><L><C><N><A><S><N... | Binds to the 23S rRNA.<BOP> | Q8KAJ0 |
P57962 | DAPF_PASMU | PLP-independent amino acid racemase | Pasteurella | <M><Q><F><S><K><M><H><G><L><G><N><D><F><V><V><V><D><A><I><T><Q><N><L><Y><F><S><P><E><T><I><K><R><L><A><D><R><H><R><G><I><G><F><D><Q><M><L><I><V><E><P><P><Y><D><P><D><L><D><F><H><Y><R><I><F><N><A><D><G><S><E><V><S><Q><C><G><N><G><A><R><C><F><A><R><F><V><T><L><K><G><L><T><D><K><K><D><I><A><V><S><T><Q><T><G><K><M><I><L><S... | Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan.<BOP> | P57962 |
B0U083 | RLMN_FRAP2 | tRNA m2A37 methyltransferase | Francisella | <M><Q><Q><D><K><I><N><L><L><G><L><N><Q><K><A><I><E><D><F><F><I><S><I><G><E><K><K><F><H><A><R><Q><V><F><K><W><I><H><K><K><G><V><I><D><F><D><S><M><T><D><L><G><K><N><L><R><N><K><L><K><E><N><A><E><I><V><I><P><K><V><V><F><N><K><A><S><K><D><G><T><H><K><W><L><I><D><V><G><G><S><A><V><E><T><V><F><I><P><E><E><G><R><G><T><L><C><V... | Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs. m2A2503 modification seems to play a crucial role in the proofreading step occurring at the peptidyl transferase center and thus would serve to optimize ribosomal fidelity.<BOP> | B0U083 |
Q8EER0 | CRCB_SHEON | Putative fluoride ion transporter CrcB | Shewanella | <M><N><N><L><L><L><V><A><L><G><G><S><I><G><A><V><F><R><Y><L><I><S><I><F><M><I><Q><V><F><G><S><S><F><P><F><G><T><L><L><V><N><V><L><G><S><F><L><M><G><V><I><Y><A><L><G><Q><M><S><H><I><S><P><E><F><K><A><L><I><G><V><G><L><L><G><A><L><T><T><F><S><T><F><S><N><E><T><L><L><L><M><Q><E><G><D><W><L><K><A><A><L><N><V><V><L><N><L><S... | Important for reducing fluoride concentration in the cell, thus reducing its toxicity.<BOP> | Q8EER0 |
Q47B65 | PANC_DECAR | Pantoate-activating enzyme | Dechloromonas | <M><Q><I><H><S><S><I><A><D><L><R><S><A><L><K><N><R><G><R><V><V><F><V><P><T><M><G><N><L><H><A><G><H><I><S><L><M><T><Q><A><R><A><H><G><D><T><V><V><A><S><I><F><V><N><R><L><Q><F><G><P><N><E><D><F><D><K><Y><P><R><T><F><Q><A><D><C><D><K><L><A><A><A><G><V><D><V><L><F><A><P><T><E><A><D><L><Y><P><E><P><Q><E><Y><T><V><E><P><P><A... | Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate.<BOP> | Q47B65 |
Q1BLY7 | DXS_BURCA | 1-deoxyxylulose-5-phosphate synthase | Burkholderia cepacia complex | <M><Y><D><L><L><K><T><I><D><D><P><A><D><L><R><R><L><D><R><R><Q><L><Q><P><L><A><D><E><L><R><A><F><V><L><D><S><V><S><K><T><G><G><H><L><S><S><N><L><G><T><V><E><L><T><I><A><L><H><Y><V><F><N><T><P><N><D><R><I><V><W><D><V><G><H><Q><T><Y><P><H><K><I><L><T><G><R><R><D><Q><M><H><S><L><R><Q><Y><D><G><I><S><G><F><P><R><R><S><E><S... | Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP).<BOP> | Q1BLY7 |
Q2RM68 | RL9_MOOTA | 50S ribosomal protein L9 | Moorella | <M><K><V><I><L><T><A><D><V><A><K><L><G><N><R><G><T><L><V><E><V><S><E><G><Y><A><R><N><Y><L><L><P><R><G><L><A><V><E><A><T><A><G><R><L><K><E><L><D><L><E><K><K><R><R><E><K><K><E><N><Q><E><L><E><N><A><R><R><Q><A><A><R><L><D><G><A><V><V><K><I><T><T><R><A><G><E><T><G><K><L><F><G><S><V><T><N><K><E><I><A><E><A><I><K><N><T><F><Q... | Binds to the 23S rRNA.<BOP> | Q2RM68 |
Q03523 | MURE_BACSU | UDP-N-acetylmuramyl-tripeptide synthetase | Bacillus | <M><K><L><T><K><L><L><T><Y><L><T><T><E><P><S><V><N><D><S><Q><D><P><E><I><T><S><I><E><M><D><S><R><E><V><K><K><G><S><L><F><V><C><V><K><G><Y><T><V><D><G><H><D><F><A><Q><K><A><V><E><N><G><A><A><A><I><V><A><E><R><E><V><D><V><N><V><P><V><I><I><V><R><Q><S><L><R><A><L><S><V><L><S><D><A><F><Y><G><Q><P><T><K><K><L><Q><L><I><G><I... | Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan.<BOP> | Q03523 |
A1E9I7 | ATPF_HORVU | ATPase subunit I | Hordeum | <M><K><N><V><T><H><S><F><V><F><L><A><H><W><P><S><A><G><S><F><G><L><N><T><D><I><L><A><T><N><L><I><N><L><T><V><V><V><G><V><L><I><F><F><G><K><G><V><L><K><D><L><L><D><N><R><K><Q><R><I><L><S><T><I><R><N><S><E><E><L><R><R><G><T><I><E><Q><L><E><K><A><R><I><R><L><Q><K><V><E><L><E><A><D><E><Y><R><M><N><G><Y><S><E><I><E><R><E><K... | Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0).<BOP> | A1E9I7 |
C1L2I5 | XERC_LISMC | Tyrosine recombinase XerC | Listeria | <M><I><Q><E><G><K><L><E><Q><Q><F><F><D><Y><L><H><S><E><R><N><Y><S><V><N><T><S><T><A><Y><E><N><D><L><L><D><F><R><R><F><L><N><E><Q><A><I><T><T><Y><Q><Q><V><T><F><L><D><V><R><I><Y><L><T><E><L><K><Q><K><S><F><S><R><T><T><V><A><R><K><I><S><S><L><R><S><F><Y><T><F><L><L><R><E><N><V><I><N><E><N><P><F><T><Y><V><S><H><A><K><N><Q... | Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plas... | C1L2I5 |
O74832 | PT127_SCHPO | mRNA degradation protein pet127, mitochondrial | Schizosaccharomyces | <M><L><I><Y><K><K><K><N><F><G><R><R><S><V><Y><N><L><K><K><C><L><H><K><G><F><Q><I><N><S><C><N><I><K><A><A><D><N><V><L><H><S><K><A><S><A><F><E><K><V><N><V><V><D><K><E><S><I><G><N><L><Q><H><H><L><D><T><V><L><P><K><K><K><F><Q><F><L><R><D><P><K><T><N><D><Y><K><W><D><E><Y><L><S><K><I><L><P><V><D><K><F><N><F><G><L><L><S><K><F... | Required for the degradation of mRNA in mitochondria.<BOP> | O74832 |
P53849 | GIS2_YEAST | Zinc finger protein GIS2 | Saccharomyces | <M><S><Q><K><A><C><Y><V><C><G><K><I><G><H><L><A><E><D><C><D><S><E><R><L><C><Y><N><C><N><K><P><G><H><V><Q><T><D><C><T><M><P><R><T><V><E><F><K><Q><C><Y><N><C><G><E><T><G><H><V><R><S><E><C><T><V><Q><R><C><F><N><C><N><Q><T><G><H><I><S><R><E><C><P><E><P><K><K><T><S><R><F><S><K><V><S><C><Y><K><C><G><G><P><N><H><M><A><K><D><C... | May act in the sexual differentiation pathway.<BOP> | P53849 |
P55555 | Y4LO_SINFN | Serine/threonine-protein acetyltransferase NGR_a02610 | Sinorhizobium | <M><Q><L><S><R><R><A><E><I><G><N><P><S><S><R><N><L><S><P><R><I><N><E><K><V><E><L><L><G><Q><A><L><E><H><A><R><R><A><G><M><S><S><S><L><M><E><Y><G><R><Q><V><A><R><H><L><S><A><N><V><Q><P><D><E><K><I><L><S><L><D><I><R><N><L><P><L><L><A><A><S><Y><N><R><R><Y><P><D><L><D><L><R><H><M><D><S><P><A><R><F><F><D><A><L><N><D><R><S><S... | Serine/threonine-protein acetyltransferase translocated into infected cells, which mediates acetylation of serine and threonine residues of host target proteins.<BOP> | P55555 |
A0KRQ2 | CCME_SHESA | Heme chaperone CcmE | Shewanella | <M><N><P><R><R><K><K><R><L><T><L><A><V><A><L><I><G><G><V><A><A><I><A><S><L><L><L><Y><A><L><N><S><N><L><N><L><F><Y><T><P><S><E><I><V><H><G><K><T><D><T><G><V><K><P><E><A><G><Q><R><I><R><V><G><G><M><V><T><V><G><S><M><V><R><D><P><N><S><L><H><V><Q><F><A><V><H><D><S><L><G><G><E><I><L><V><T><Y><D><D><L><L><P><D><L><F><R><E><G... | Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH.<BOP> | A0KRQ2 |
Q81JA6 | RNM5_BACCR | Ribosomal RNA terminal maturase M5 | Bacillus cereus group | <M><E><A><S><M><K><I><K><E><I><I><V><V><E><G><K><D><D><T><V><A><I><K><R><A><V><D><A><D><T><I><E><T><N><G><S><A><I><G><D><H><V><I><E><Q><V><K><L><A><Q><Q><K><R><G><V><I><I><F><T><D><P><D><Y><P><G><E><R><I><R><K><I><I><S><D><K><V><P><G><C><K><H><A><F><L><P><K><E><E><A><L><A><K><R><K><K><G><V><G><I><E><H><A><S><N><E><S><I... | Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step.<BOP> | Q81JA6 |
A1B012 | RL1_PARDP | 50S ribosomal protein L1 | Paracoccus | <M><A><K><L><S><K><K><Q><V><S><A><R><A><A><F><A><G><K><S><N><L><A><V><E><E><A><V><K><L><V><K><E><N><A><S><A><K><F><D><E><T><V><E><I><A><M><N><L><G><V><D><P><R><H><A><D><Q><M><V><R><G><V><V><T><L><P><N><G><T><G><K><D><V><R><V><A><V><F><A><R><G><P><K><A><D><E><A><K><A><A><G><A><E><I><V><G><A><E><D><L><M><E><T><I><Q><S><G... | Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.<BOP> | A1B012 |
Q64TM7 | DNLJ_BACFR | Polydeoxyribonucleotide synthase [NAD(+)] | Bacteroides | <M><T><V><K><E><K><I><E><Q><L><R><L><Q><L><H><Q><H><N><Y><N><Y><Y><V><L><N><A><P><E><I><S><D><K><E><F><D><D><L><M><R><E><L><Q><D><L><E><Q><E><H><P><E><Y><K><D><E><N><S><P><T><M><R><V><G><S><D><I><N><K><N><F><T><Q><V><A><H><K><Y><P><M><L><S><L><S><N><T><Y><S><E><N><E><V><T><D><F><Y><D><R><V><R><K><A><L><N><E><D><F><E><I... | DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA.<BOP> | Q64TM7 |
C6HEL8 | LCL2_AJECH | Long chronological lifespan protein 2 | Histoplasma | <M><V><H><I><F><T><G><I><L><L><G><L><L><L><L><A><T><G><T><Q><A><Q><F><Q><F><F><E><Q><M><F><G><G><G><Q><Q><Q><Q><H><D><S><R><E><Q><N><V><P><S><D><S><D><W><Y><Q><R><T><Y><D><N><A><R><C><S><N><Y><L><C><P><G><T><L><A><C><V><A><V><P><H><H><C><P><C><Q><H><P><A><V><E><D><K><F><E><L><G><D><G><S><A><I><C><V><S><K><G><G><F><K><F... | Probable component of the endoplasmic reticulum-associated degradation (ERAD) pathway.<BOP> | C6HEL8 |
Q722T9 | AZOR1_LISMF | FMN-dependent NADH-azoreductase 1 | Listeria | <M><T><N><V><L><F><I><K><A><N><G><L><P><A><E><R><S><V><S><V><A><L><Y><E><I><F><L><T><E><Y><K><K><S><H><P><D><D><N><V><T><E><L><D><L><F><E><A><D><L><P><Y><Y><D><V><T><M><M><S><G><L><H><K><E><A><A><G><E><T><L><S><P><E><E><K><R><L><A><D><I><A><N><S><Y><L><D><Q><F><L><A><A><D><K><I><V><M><A><F><P><L><W><N><F><S><I><P><A><Q... | Also exhibits azoreductase activity. Catalyzes the reductive cleavage of the azo bond in aromatic azo compounds to the corresponding amines.<BOP> | Q722T9 |
Q95730 | CYB_ARTGW | Ubiquinol-cytochrome-c reductase complex cytochrome b subunit | Artibeus | <M><T><N><I><R><K><T><H><P><L><L><K><I><I><N><S><S><F><V><D><L><P><A><P><S><S><L><S><S><W><W><N><F><G><S><L><L><G><V><C><L><G><V><Q><I><L><T><G><L><F><L><A><M><H><Y><T><S><D><T><A><T><A><F><N><S><V><N><H><I><C><R><D><V><N><Y><G><W><L><L><R><Y><L><H><A><N><G><A><S><M><F><F><I><C><L><Y><L><H><V><G><R><G><L><Y><Y><G><S><Y... | Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain. The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c. Contributes to the generation of a proton gradient across the mitochondrial membrane that is... | Q95730 |
Q9HDB9 | GAK5_HUMAN | HERV-K_3q12.3 provirus ancestral Gag polyprotein | Homo | <M><G><Q><T><K><S><K><T><K><S><K><Y><A><S><Y><L><S><F><I><K><I><L><L><K><R><G><G><V><R><V><S><T><K><N><L><I><K><L><F><Q><I><I><E><Q><F><C><P><W><F><P><E><Q><G><T><L><D><L><K><D><W><K><R><I><G><E><E><L><K><Q><A><G><R><K><G><N><I><I><P><L><T><V><W><N><D><W><A><I><I><K><A><A><L><E><P><F><Q><T><K><E><D><S><V><S><V><S><D><A... | The products of the Gag polyproteins of infectious retroviruses perform highly complex orchestrated tasks during the assembly, budding, maturation, and infection stages of the viral replication cycle. During viral assembly, the proteins form membrane associations and self-associations that ultimately result in budding ... | Q9HDB9 |
P37528 | PDXT_BACSU | Pyridoxal 5'-phosphate synthase glutaminase subunit | Bacillus | <M><L><T><I><G><V><L><G><L><Q><G><A><V><R><E><H><I><H><A><I><E><A><C><G><A><A><G><L><V><V><K><R><P><E><Q><L><N><E><V><D><G><L><I><L><P><G><G><E><S><T><T><M><R><R><L><I><D><T><Y><Q><F><M><E><P><L><R><E><F><A><A><Q><G><K><P><M><F><G><T><C><A><G><L><I><I><L><A><K><E><I><A><G><S><D><N><P><H><L><G><L><L><N><V><V><V><E><R><N... | Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS.<BOP> | P37528 |
A1B673 | ILVD_PARDP | Dihydroxy-acid dehydratase | Paracoccus | <M><P><A><Y><R><S><R><T><T><T><H><G><R><N><M><A><G><A><R><G><L><W><R><A><T><G><V><K><N><S><D><F><G><K><P><I><I><A><I><V><N><S><F><T><Q><F><V><P><G><H><V><H><L><K><D><L><G><Q><M><V><A><R><E><V><E><A><A><G><G><I><A><K><E><F><N><T><I><A><V><D><D><G><I><A><M><G><H><D><G><M><L><Y><S><L><P><S><R><E><L><I><A><D><S><V><E><Y><M... | Functions in the biosynthesis of branched-chain amino acids. Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (... | A1B673 |
P80972 | COX5A_THUOB | Cytochrome c oxidase polypeptide Va-1 | Thunnus | <S><H><G><K><V><E><T><D><E><E><F><D><A><R><W><V><T><Y><F><S> | Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CII... | P80972 |
Q9UU82 | AREH2_SCHPO | Sterol-ester synthase 2 | Schizosaccharomyces | <M><I><A><A><T><P><A><K><S><K><P><S><D><V><N><L><E><Q><T><F><K><G><V><S><E><T><S><K><I><D><L><R><R><S><R><A><A><Y><R><P><L><E><L><S><P><T><P><S><I><F><A><R><N><Y><Q><R><N><A><V><D><F><T><G><F><F><V><L><F><W><V><A><V><S><I><M><I><F><M><S><F><L><E><N><F><E><L><T><G><R><P><V><V><G><T><I><F><K><Y><F><Q><S><N><L><L><D><L><A... | Sterol O-acyltransferase that catalyzes the formation of stery esters.<BOP> | Q9UU82 |
Q9I900 | PA2AD_NAJSP | Phosphatidylcholine 2-acylhydrolase | Naja | <M><N><P><A><H><L><L><I><L><A><A><V><C><V><S><P><L><G><A><S><S><N><R><P><M><P><L><N><L><Y><Q><F><K><N><M><I><Q><C><T><V><P><N><R><S><W><W><D><F><A><D><Y><G><C><Y><C><G><R><G><G><S><G><T><P><V><D><D><L><D><R><C><C><Q><V><H><D><N><C><Y><G><E><A><E><K><I><S><R><C><W><P><Y><F><K><T><Y><S><Y><E><C><S><Q><G><T><L><T><C><K><G... | PLA2 catalyzes the calcium-dependent hydrolysis of the 2-acyl groups in 3-sn-phosphoglycerides.<BOP> | Q9I900 |
Q820N6 | UVRC_NITEU | Excinuclease ABC subunit C | Nitrosomonas | <M><P><D><A><H><F><D><G><K><A><F><V><L><T><L><P><A><Q><P><G><V><Y><R><M><L><N><A><A><G><D><V><I><Y><V><G><K><A><I><D><L><R><K><R><V><S><S><Y><F><Q><K><S><G><L><S><P><R><I><Q><L><M><V><S><Q><I><A><G><I><E><T><T><V><T><R><S><E><A><E><A><L><L><L><E><N><N><L><I><K><S><L><A><P><R><Y><N><I><L><F><R><D><D><K><S><Y><P><Y><L><L... | The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.<BOP> | Q820N6 |
Q1C6R0 | NAGK_YERPA | GlcNAc kinase | Yersinia | <M><Y><Y><G><F><D><M><G><G><T><K><I><E><L><G><V><F><D><E><N><L><Q><R><I><W><H><K><R><V><P><T><P><R><E><D><Y><P><Q><L><L><Q><I><L><R><D><L><T><E><E><A><D><T><Y><C><G><V><Q><G><S><V><G><I><G><I><P><G><L><P><N><A><D><D><G><T><V><F><T><A><N><V><P><S><A><M><G><Q><P><L><Q><A><D><L><S><R><L><I><Q><R><E><V><R><I><D><N><D><A><N... | Catalyzes the phosphorylation of N-acetyl-D-glucosamine (GlcNAc) derived from cell-wall degradation, yielding GlcNAc-6-P.<BOP> | Q1C6R0 |
B7J8G6 | RLME_ACIF2 | rRNA (uridine-2'-O-)-methyltransferase | Acidithiobacillus | <M><A><R><S><K><S><S><E><K><W><L><K><E><H><F><K><D><P><F><V><Q><R><A><M><K><E><G><Y><R><S><R><A><S><Y><K><L><L><E><I><Q><Q><K><D><H><L><I><R><P><G><M><R><V><L><D><V><G><A><A><P><G><G><W><T><Q><V><A><A><P><L><I><G><R><K><G><R><L><V><A><V><D><R><L><A><M><D><P><V><A><D><A><T><V><I><C><G><D><V><Y><D><D><A><I><L><A><A><C><Q... | Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit.<BOP> | B7J8G6 |
Q06655 | LALBA_NOTEU | Lactose synthase B protein | Notamacropus | <M><M><S><L><L><S><L><L><L><L><G><I><A><L><P><A><T><Q><A><I><D><Y><R><K><C><Q><A><S><Q><I><L><K><E><H><G><M><D><K><V><I><P><L><P><E><L><V><C><T><M><F><H><I><S><G><L><S><T><Q><A><E><V><N><N><H><S><N><K><E><Y><G><I><F><Q><I><S><N><N><G><W><C><A><E><K><Q><E><D><V><A><N><S><V><C><G><I><L><C><S><K><F><L><D><D><D><I><T><D><D... | Regulatory subunit of lactose synthase, changes the substrate specificity of galactosyltransferase in the mammary gland making glucose a good acceptor substrate for this enzyme. This enables LS to synthesize lactose, the major carbohydrate component of milk. In other tissues, galactosyltransferase transfers galactose o... | Q06655 |
Q6FKS5 | HAT1_CANGA | Histone acetyltransferase type B catalytic subunit | Nakaseomyces/Candida clade | <M><S><I><D><D><F><K><P><E><K><W><T><I><S><S><N><E><A><L><K><L><S><L><V><S><E><D><N><A><I><Q><F><S><P><T><F><T><Y><P><I><F><G><T><E><E><Q><I><F><G><Y><K><D><L><V><I><H><L><A><F><D><A><I><T><F><K><P><F><L><N><V><K><F><S><S><K><F><E><G><S><E><E><E><L><V><N><I><K><E><K><L><L><E><Y><L><P><I><D><D><T><I><Y><K><D><E><E><K><W... | Catalytic component of the histone acetylase B (HAT-B) complex. Acetylates 'Lys-12' of histone H4 which is required for telomeric silencing. Has intrinsic substrate specificity that modifies lysine in recognition sequence GXGKXG. Involved in DNA double-strand break repair.<BOP> | Q6FKS5 |
C4KZN4 | RL5_EXISA | 50S ribosomal protein L5 | unclassified Exiguobacterium | <M><N><R><L><Q><E><K><Y><K><S><D><I><V><K><A><M><M><D><K><F><N><Y><D><S><V><M><Q><V><P><K><I><E><K><I><V><I><N><M><G><V><G><D><A><V><S><N><S><K><A><L><D><M><A><V><E><E><L><T><I><L><S><G><Q><K><P><L><V><T><K><A><K><K><S><I><A><G><F><K><L><R><E><G><M><P><I><G><A><K><V><T><L><R><G><E><R><M><Y><D><F><L><D><K><L><V><T><V><S... | This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement... | C4KZN4 |
B0S8X7 | ACSA_LEPBA | Acyl-activating enzyme | Leptospira | <M><P><K><E><R><I><V><A><P><S><K><E><F><A><K><L><A><N><V><S><L><K><E><Y><K><S><K><Y><K><E><S><I><E><K><P><E><K><F><W><A><E><Q><A><K><R><L><T><W><F><K><K><W><T><K><V><L><R><H><D><F><A><K><A><K><V><E><W><F><V><G><G><K><L><N><V><S><Y><N><C><L><D><R><H><L><D><S><P><L><K><N><K><A><A><L><I><W><E><G><D><N><P><D><E><S><K><V><L... | Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can the... | B0S8X7 |
P39825 | PROF_SCHPO | Profilin | Schizosaccharomyces | <M><S><W><Q><A><Y><V><D><T><S><L><L><G><T><G><K><I><D><R><A><A><I><V><S><R><A><G><D><S><V><W><A><A><S><A><G><F><N><L><S><P><Q><E><I><Q><G><L><A><A><G><F><Q><D><P><P><S><M><F><G><T><G><I><I><L><A><G><Q><K><Y><I><T><I><R><A><E><G><R><S><I><Y><G><K><L><Q><K><E><G><I><I><C><V><A><T><K><L><C><I><L><V><S><H><Y><P><E><T><T><L... | Binds to actin and affects the structure of the cytoskeleton. At high concentrations, profilin prevents the polymerization of actin, whereas it enhances it at low concentrations. By binding to PIP2, it inhibits the formation of IP3 and DG. In S.pombe, it is essential for cytokinesis.<BOP> | P39825 |
Q4QMR6 | COAD_HAEI8 | Pantetheine-phosphate adenylyltransferase | Haemophilus | <M><T><S><V><I><Y><P><G><T><F><D><P><I><T><N><G><H><L><D><I><I><E><R><S><A><V><I><F><P><R><V><L><V><A><V><A><N><S><P><S><K><K><P><L><F><S><L><E><E><R><V><E><L><V><R><Q><S><V><A><H><L><S><N><V><E><V><F><G><F><S><D><L><L><A><N><V><I><K><Q><H><N><I><S><A><I><I><R><G><V><R><T><T><T><D><F><E><Y><E><L><Q><L><A><A><L><N><R><L... | Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.<BOP> | Q4QMR6 |
P02507 | CRYAA_PELLE | Alpha-crystallin A chain | Pelophylax | <M><D><I><T><I><Q><H><P><W><F><K><R><A><L><G><P><F><Y><P><N><R><L><F><D><Q><V><F><G><E><G><M><F><D><Y><D><L><F><P><F><L><S><S><T><I><S><P><Y><Y><R><Q><S><F><F><R><G><F><L><D><S><G><I><S><E><V><R><S><D><R><D><R><V><K><H><F><S><P><E><D><L><T><V><K><I><L><D><D><F><V><E><I><H><G><K><H><S><E><R><Q><D><D><H><G><Y><I><S><R><E... | Contributes to the transparency and refractive index of the lens. May act as a chaperone, preventing aggregation of various proteins under a wide range of stress conditions.<BOP> | P02507 |
A5VB97 | LEXA_RHIWR | LexA repressor | Rhizorhabdus | <M><L><T><R><K><Q><H><E><L><L><C><F><I><N><D><R><L><L><Q><T><G><V><S><P><S><F><E><E><M><K><E><A><L><D><L><K><S><K><S><G><V><H><R><L><I><S><A><L><E><E><R><N><F><I><R><R><L><P><N><R><A><R><A><L><E><V><L><R><M><P><E><T><A><T><A><K><P><T><A><A><A><S><G><K><A><K><A><A><A><P><A><V><P><Q><A><A><N><E><N><V><L><E><I><P><L><H><G... | Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair... | A5VB97 |
B8F877 | NAGB_GLAP5 | Glucosamine-6-phosphate isomerase | Glaesserella | <M><R><L><V><P><L><D><C><A><E><Q><V><S><R><W><A><A><R><Y><I><V><D><K><I><N><A><F><Q><P><T><A><E><K><P><F><V><L><G><L><P><T><G><G><T><P><L><Q><T><Y><K><E><L><I><K><L><Y><Q><A><G><E><V><S><F><K><H><V><V><T><F><N><M><D><E><Y><V><G><L><P><P><E><H><K><E><S><Y><H><Y><F><M><F><H><N><F><F><N><H><I><D><I><P><V><E><N><V><N><I><L... | Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion.<BOP> | B8F877 |
O08970 | TUFT1_MOUSE | Tuftelin | Mus | <M><N><G><T><R><N><W><C><T><L><V><D><V><H><P><E><S><Q><T><A><G><S><V><D><I><L><R><L><T><L><Q><S><E><L><T><G><D><E><L><E><H><I><A><Q><K><A><G><R><K><T><Y><A><M><M><P><G><H><S><S><G><H><S><L><A><S><E><L><V><E><S><H><D><G><H><E><E><I><I><K><V><Y><L><K><G><R><S><G><D><K><M><T><H><E><K><N><I><D><Q><L><K><S><E><V><Q><Y><I><Q... | Involved in the mineralization and structural organization of enamel.<BOP> | O08970 |
A0PM42 | EFTU_MYCUA | Elongation factor Tu | Mycobacterium | <M><A><K><A><K><F><Q><R><T><K><P><H><V><N><I><G><T><I><G><H><V><D><H><G><K><T><T><L><T><A><A><I><T><K><V><L><H><D><K><Y><P><E><L><N><E><S><R><A><F><D><Q><I><D><N><A><P><E><E><R><Q><R><G><I><T><I><N><I><S><H><V><E><Y><Q><T><E><K><R><H><Y><A><H><V><D><A><P><G><H><A><D><Y><I><K><N><M><I><T><G><A><A><Q><M><D><G><A><I><L><V... | This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.<BOP> | A0PM42 |
B2J0A6 | RSMA_NOSP7 | S-adenosylmethionine-6-N', N'-adenosyl(rRNA) dimethyltransferase | Nostoc | <M><I><R><P><R><K><V><F><A><Q><H><W><L><K><S><E><K><A><L><D><A><I><I><K><A><A><E><C><T><E><S><D><R><S><P><K><G><D><C><I><L><E><I><G><P><G><T><G><I><L><T><R><R><L><L><P><L><V><Q><S><L><I><A><V><E><I><D><R><D><L><C><Q><L><L><S><K><Q><L><G><K><T><E><N><F><L><L><L><Q><G><D><F><L><T><L><D><L><P><S><Y><L><V><A><F><P><N><F><Q... | Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits.<BOP> | B2J0A6 |
A9MJF0 | HUTU_SALAR | Imidazolonepropionate hydrolase | Salmonella | <M><P><E><S><K><Y><R><Q><Q><T><I><R><A><P><R><G><A><T><L><T><A><K><S><W><L><T><E><A><P><L><R><M><L><M><N><N><L><D><P><D><V><A><E><N><P><H><E><L><V><V><Y><G><G><I><G><R><A><A><R><N><W><E><C><Y><D><A><I><V><D><A><L><T><R><L><E><A><D><E><T><L><L><I><Q><S><G><K><P><V><G><V><F><K><T><H><D><N><A><P><R><V><L><I><A><N><S><N><L... | Catalyzes the conversion of urocanate to 4-imidazolone-5-propionate.<BOP> | A9MJF0 |
Q38Y19 | TPIS_LATSS | Triose-phosphate isomerase | Latilactobacillus | <M><R><K><P><I><I><A><G><N><W><K><M><N><M><N><P><T><Q><T><T><E><F><V><N><A><I><K><A><N><L><P><K><F><D><Q><T><E><S><V><I><G><A><P><A><V><D><L><P><A><L><L><E><A><A><K><G><T><D><L><K><V><A><A><E><N><C><Y><F><E><E><A><G><A><F><T><G><E><T><S><P><K><T><L><N><E><M><G><V><D><Y><V><I><I><G><H><S><E><R><R><D><Y><F><H><E><T><D><E... | Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).<BOP> | Q38Y19 |
Q554U9 | EIF3D_DICDI | eIF-3-zeta | Dictyostelium | <M><S><L><E><L><N><T><I><K><V><N><P><T><G><W><G><P><V><G><K><L><E><K><F><T><D><I><P><Y><A><P><F><S><K><G><D><K><I><G><K><C><S><D><W><N><S><N><V><R><N><Y><Q><R><Q><N><Y><G><S><N><A><F><N><P><F><T><F><K><L><E><D><D><E><D><S><F><T><L><V><D><Y><T><R><V><Q><N><K><L><K><N><K><G><K><T><Y><Q><K><Q><F><Y><Q><Q><N><K><R><G><G><S... | mRNA cap-binding component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically target... | Q554U9 |
Q7NFN6 | RIMP_GLOVI | Ribosome maturation factor RimP | Gloeobacter | <M><N><P><R><D><I><V><E><Q><V><T><A><L><A><E><P><V><A><E><Q><L><G><L><Q><L><V><A><V><A><Y><Q><T><H><T><K><P><A><T><L><R><V><D><I><R><H><P><T><E><G><T><G><L><D><D><C><E><K><M><S><R><A><L><E><A><L><L><D><T><R><D><D><L><I><I><G><A><Y><N><L><E><V><S><S><P><G><V><E><R><V><L><T><T><D><R><E><F><M><A><F><R><G><F><P><V><M><V><K... | Required for maturation of 30S ribosomal subunits.<BOP> | Q7NFN6 |
B3CQP5 | LIPA_ORITI | Sulfur insertion protein LipA | Orientia | <M><C><S><D><K><N><I><T><A><T><A><L><V><R><P><S><W><L><R><V><K><A><P><F><S><D><E><Y><Q><S><T><N><E><L><I><K><S><L><K><L><N><T><V><C><K><E><A><A><C><P><N><I><G><E><C><W><S><K><K><H><A><T><V><M><I><L><G><S><I><C><T><R><A><C><A><F><C><N><V><S><T><G><K><P><E><Q><V><D><E><Y><E><P><Y><R><L><S><E><A><V><M><K><L><G><L><K><H><V... | Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.<BOP> | B3CQP5 |
P49258 | CALL_DROME | Protein androcam | Sophophora | <M><S><E><L><T><E><E><Q><I><A><E><F><K><D><A><F><V><Q><F><D><K><E><G><T><G><K><I><A><T><R><E><L><G><T><L><M><R><T><L><G><Q><N><P><T><E><A><E><L><Q><D><L><I><A><E><A><E><N><N><N><N><G><Q><L><N><F><T><E><F><C><G><I><M><A><K><Q><M><R><E><T><D><T><E><E><E><M><R><E><A><F><K><I><F><D><R><D><G><D><G><F><I><S><P><A><E><L><R><F... | May be involved in calcium-mediated signal transduction.<BOP> | P49258 |
Q1XDB1 | RPOZ_NEOYE | Plastid-encoded RNA polymerase omega subunit | Neopyropia | <M><N><Q><H><N><S><L><D><S><S><D><I><T><Y><K><T><E><E><L><L><E><A><T><T><N><R><Y><K><I><T><V><Q><V><A><N><R><A><K><R><R><K><Y><E><D><V><D><I><I><D><D><P><Q><V><K><P><V><I><R><A><I><L><E><M><V><D><E><I><T><Q><P><E><I><I><S><D> | May be involved in RNA polymerase activity.<BOP> | Q1XDB1 |
Q82QR5 | RPOA2_STRAW | Transcriptase subunit alpha | Streptomyces | <M><L><I><A><Q><R><P><S><L><T><E><E><V><V><D><E><F><R><S><R><F><V><I><E><P><L><E><P><G><F><G><Y><T><L><G><N><S><L><R><R><T><L><L><S><S><I><P><G><A><A><V><T><S><I><R><V><D><G><V><L><H><E><F><T><T><V><P><G><V><K><E><D><V><T><D><L><I><L><N><I><K><Q><L><V><V><S><S><E><H><D><E><P><V><V><M><Y><L><R><K><Q><G><P><G><L><V><T><A... | DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.<BOP> | Q82QR5 |
P28092 | WNT7_EVATR | Protein Wnt-7 | Evasterias | <S><G><S><C><T><T><K><T><C><W><T><T><L><P><P><F><R><L><V><G><N><I><L><K><Q><K><Y><E><K><P><V><Q><V><E><P><V><R><A><R><R><T><R><R><P><A><F><L><K><I><K><D><I><K><N><F><K><K><P><R><P><T><D><M><V><Y><L><Q><R><S><P><N><Y><C><D><R><D><P><R><V><G><S><L><G><T><V><G><R><Q><C><N><R><T><S><I><G><T><D><S><C><D><L><M><C><C><G><R><G... | Ligand for members of the frizzled family of seven transmembrane receptors. Probable developmental protein. May be a signaling molecule which affects the development of discrete regions of tissues. Is likely to signal over only few cell diameters.<BOP> | P28092 |
A0PLD8 | Y450_MYCUA | Putative S-adenosyl-L-methionine-dependent methyltransferase MUL_0450 | Mycobacterium | <M><V><R><T><D><R><D><R><W><D><L><A><T><S><V><G><A><T><A><T><M><V><A><A><Q><R><A><L><A><A><D><P><Q><Y><A><L><I><D><D><P><Y><A><A><P><L><V><R><A><V><D><I><D><V><Y><T><R><L><V><N><G><Q><I><P><V><D><V><E><S><G><F><D><P><A><R><M><P><E><A><M><A><C><R><T><R><F><Y><D><Q><F><F><V><D><A><T><R><S><G><I><S><Q><V><V><I><L><A><S><G... | Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity.<BOP> | A0PLD8 |
Q03F61 | YBEY_PEDPA | Endoribonuclease YbeY | Pediococcus | <M><D><I><Q><T><F><D><H><T><K><E><E><N><P><K><N><L><E><L><I><T><D><I><L><E><F><A><G><N><Y><L><H><L><D><E><E><T><E><I><S><V><T><L><M><H><N><D><E><I><H><Q><I><N><K><E><Y><R><N><V><D><R><P><T><D><V><I><S><F><A><I><N><D><A><D><E><D><I><I><M><D><P><E><M><A><E><E><I><P><A><N><I><G><D><L><M><I><S><V><D><K><V><A><E><Q><A><E><F... | Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.<BOP> | Q03F61 |
P0DKN2 | TUB1_LOPOL | OL105 | Iotyrris | <M><A><R><Q><M><M><T><V><G><C><L><I><L><I><V><V><L><L><D><M><M><V><P><V><F><N><T><C><P><G><Q><Y><D><E><C><G><N><G><P><E><E><G><E><C><C><G><T><H><N><Y><C><C><K><N><A><C><T><T><Y><H><H><C><H><G><G><R><D><A><G><K><L><L><R><S><L><K><K><L><K><L><T><T><H> | Acts as a neurotoxin by inhibiting voltage-gated potassium channels (Kv).<BOP> | P0DKN2 |
B3LMP9 | MIC12_YEAS1 | Found in mitochondrial proteome protein 51 | Saccharomyces | <M><S><K><L><G><P><L><A><R><S><V><K><W><T><L><S><V><G><V><I><G><S><V><F><Y><L><Y><R><Y><S><N><N><G><Y><F><Y><D><H><D><A><T><W><L><K><Q><D><H><Q><V><Q><D><L><V><D><R><K><E><V><V><P><G><E><T><R><N><R><K><L><V><V><T><D><D><G><T><A><W><S><R><T><M><G><E><S><I><K><D><I><W><N><E><Q><I><R><N><S><V><D><W><I><Y><S><W><G><K><N> | Component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane.<BOP> | B3LMP9 |
Q2JV01 | PLSY_SYNJA | Lysophosphatidic acid synthase | unclassified Synechococcus | <M><P><A><W><L><S><A><L><L><A><A><L><G><G><Y><L><L><G><S><I><P><T><G><Y><W><V><G><R><C><W><G><G><I><D><L><R><Q><A><G><S><G><S><T><G><A><T><N><V><L><R><T><V><G><K><G><P><A><L><L><V><L><L><V><D><A><A><K><G><A><A><A><V><A><L><G><S><A><L><G><S><P><W><W><V><V><V><A><A><L><G><A><V><I><G><H><S><R><S><C><W><L><G><F><K><G><G><K... | Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP.<BOP> | Q2JV01 |
Q9JVC0 | TRPB_NEIMA | Tryptophan synthase beta chain | Neisseria | <M><K><N><Y><H><A><P><D><E><K><G><F><F><G><E><H><G><G><L><F><V><S><E><T><L><I><P><A><L><Q><E><L><A><D><A><Y><K><A><A><K><N><D><P><E><F><W><E><A><F><R><H><D><L><K><H><Y><V><G><R><P><S><P><V><Y><H><A><A><R><L><S><E><H><L><G><G><A><Q><I><W><L><K><R><E><D><L><N><H><T><G><A><H><K><V><N><N><T><I><G><Q><A><L><L><A><K><R><M><G... | The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.<BOP> | Q9JVC0 |
A7H295 | SYE1_CAMJD | Glutamyl-tRNA synthetase 1 | Campylobacter | <M><H><E><K><L><T><T><R><F><A><P><S><P><T><G><Y><L><H><I><G><G><L><R><T><A><L><Y><N><Y><L><Y><A><R><K><N><G><G><N><F><L><L><R><I><E><D><T><D><L><K><R><N><S><K><E><A><T><K><A><I><I><E><A><F><K><W><C><G><L><E><H><D><G><E><V><T><Y><Q><S><E><R><F><D><L><Y><K><E><Y><V><K><K><L><L><D><E><G><K><A><Y><Y><C><Y><M><S><K><E><E><L... | Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).<BOP> | A7H295 |
A6TF07 | CYSG2_KLEP7 | Sirohydrochlorin ferrochelatase 2 | Klebsiella | <M><D><H><L><P><I><F><C><Q><L><R><Q><R><D><C><L><L><V><G><G><G><D><V><A><E><R><K><A><R><L><L><L><D><A><G><A><N><V><T><V><N><A><L><D><F><T><P><Q><F><Q><V><W><A><D><S><Q><M><L><T><L><V><Q><G><E><F><I><P><S><L><L><D><N><C><W><L><A><I><A><A><T><D><D><E><T><V><N><Q><Q><V><S><E><A><A><E><A><R><R><I><F><C><N><V><V><D><A><P><R... | Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yie... | A6TF07 |
B2HQM5 | THIC_MYCMM | Thiamine biosynthesis protein ThiC | Mycobacterium | <M><T><V><T><V><E><P><S><I><T><T><G><P><I><A><G><S><S><K><A><Y><R><E><V><A><G><P><D><G><V><T><L><R><V><P><L><R><R><V><H><L><S><T><G><A><D><F><D><L><Y><D><T><S><G><P><Y><T><D><P><N><A><V><I><D><L><A><V><G><L><P><A><R><P><G><L><V><R><D><R><G><T><Q><L><Q><R><A><R><A><G><E><I><T><A><E><M><A><F><I><A><A><R><E><G><M><S><A><E... | Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.<BOP> | B2HQM5 |
Q83I60 | KAD_TROW8 | Adenylate monophosphate kinase | Tropheryma | <M><R><A><I><M><V><G><P><P><G><S><G><K><G><T><Q><C><G><L><I><Q><S><R><L><G><I><S><V><I><A><T><G><D><V><F><R><E><R><M><K><T><D><M><A><L><R><D><I><V><S><S><G><G><Y><V><S><D><S><T><T><N><R><I><V><E><D><C><L><D><K><E><D><V><S><S><G><F><V><L><D><G><Y><P><R><T><L><Q><Q><L><D><F><L><E><G><F><L><K><R><R><A><L><T><L><D><A><V><F... | Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.<BOP> | Q83I60 |
Q2VEF8 | PSAJ_SOLTU | PSI-J | Solanum | <M><R><D><L><K><T><Y><L><S><V><A><P><V><L><S><T><L><W><F><G><A><L><A><G><L><L><I><E><I><N><R><F><F><P><D><A><L><T><F><P><F><F> | May help in the organization of the PsaE and PsaF subunits.<BOP> | Q2VEF8 |
A7ZJC5 | NADA_ECO24 | Quinolinate synthase | Escherichia | <M><S><V><M><F><D><P><D><T><A><I><Y><P><F><P><P><K><P><T><P><L><S><I><D><E><K><A><Y><Y><R><E><K><I><K><R><L><L><K><E><R><N><A><V><M><V><A><H><Y><Y><T><D><P><E><I><Q><Q><L><A><E><E><T><G><G><C><I><S><D><S><L><E><M><A><R><F><G><A><K><H><P><A><S><T><L><L><V><A><G><V><R><F><M><G><E><T><A><K><I><L><S><P><E><K><T><I><L><M><P... | Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate.<BOP> | A7ZJC5 |
A9BEC8 | PURA_PROM4 | IMP--aspartate ligase | Prochlorococcus | <M><A><N><V><V><V><I><G><A><Q><W><G><D><E><G><K><G><K><I><T><D><L><L><S><R><S><A><D><V><V><V><R><Y><Q><G><G><V><N><A><G><H><T><I><V><V><E><D><K><V><L><K><L><H><L><I><P><S><G><I><L><Y><P><E><T><I><C><L><I><G><S><G><T><V><V><D><P><K><V><M><L><K><E><I><E><M><L><I><E><N><D><I><D><I><S><G><L><Q><L><A><S><T><A><H><V><T><M><P... | Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP.<BOP> | A9BEC8 |
A8YUL5 | THII_LACH4 | tRNA 4-thiouridine synthase | Lactobacillus | <M><E><Y><T><E><V><M><V><R><Y><G><E><L><S><T><K><G><K><N><R><K><D><F><I><N><R><L><A><S><N><V><E><K><V><L><K><D><L><P><Q><I><D><F><H><P><R><H><D><R><M><H><I><V><L><N><G><A><P><F><A><E><V><D><K><R><L><K><K><V><F><G><I><Q><T><Y><S><P><A><I><K><I><P><K><T><L><E><D><I><E><K><T><S><L><E><L><M><Q><E><T><F><K><P><G><M><T><F><K... | Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynt... | A8YUL5 |
B1XSV3 | HIS6_POLNS | ImGP synthase subunit HisF | Polynucleobacter | <M><L><T><K><R><I><I><P><C><L><D><V><T><A><G><R><V><V><K><G><V><N><F><V><G><L><R><D><A><G><D><P><V><E><I><A><K><R><Y><D><T><Q><G><A><D><E><L><T><F><L><D><I><T><A><T><S><D><G><R><D><L><I><L><H><I><I><E><D><V><A><S><Q><V><F><I><P><L><T><V><G><G><G><V><R><T><V><A><D><V><R><R><L><L><N><A><G><A><D><K><V><S><M><N><S><S><A><V... | IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.<BOP> | B1XSV3 |
A8NR45 | ACEA_COPC7 | Threo-D(S)-isocitrate glyoxylate-lyase | Coprinopsis | <M><S><S><E><R><A><Q><F><A><A><E><V><A><E><V><E><R><W><W><K><S><P><R><F><A><R><V><N><R><P><Y><T><A><A><D><V><V><S><K><R><G><T><I><K><I><N><Y><P><S><D><V><Q><G><K><K><L><W><K><L><L><S><E><H><A><K><N><G><T><P><S><H><T><Y><G><A><L><D><P><V><Q><V><T><Q><M><A><K><Y><L><E><T><V><Y><V><S><G><W><Q><S><S><S><T><A><S><S><S><N><E... | Catalyzes the formation of succinate and glyoxylate from isocitrate, a key step of the glyoxylate cycle, which operates as an anaplerotic route for replenishing the tricarboxylic acid cycle. Required for growth on ethanol or acetate, but dispensable when fermentable carbon sources are available. Acts also on 2-methylis... | A8NR45 |
P05162 | LEG2_HUMAN | S-Lac lectin 2 | Homo | <M><T><G><E><L><E><V><K><N><M><D><M><K><P><G><S><T><L><K><I><T><G><S><I><A><D><G><T><D><G><F><V><I><N><L><G><Q><G><T><D><K><L><N><L><H><F><N><P><R><F><S><E><S><T><I><V><C><N><S><L><D><G><S><N><W><G><Q><E><Q><R><E><D><H><L><C><F><S><P><G><S><E><V><K><F><T><V><T><F><E><S><D><K><F><K><V><K><L><P><D><G><H><E><L><T><F><P><N... | This protein binds beta-galactoside. Its physiological function is not yet known.<BOP> | P05162 |
A0A1L8HV70 | DCK1_XENLA | Deoxyguanosine kinase 1 | Xenopus | <M><A><T><P><P><K><R><I><C><I><D><V><P><A><S><P><S><G><N><K><C><K><V><K><R><I><S><I><E><G><N><I><A><A><G><K><S><T><F><V><N><I><L><K><K><A><N><E><E><W><D><V><V><P><E><P><I><A><R><W><C><N><I><Q><S><C><K><D><E><F><E><E><L><T><T><S><Q><K><S><G><G><N><L><L><Q><M><M><Y><E><K><P><E><R><W><S><F><T><F><Q><S><Y><A><C><L><S><R><I... | Phosphorylates the deoxyribonucleosides deoxyadenosine, deoxycytidine and deoxyguanosine with highest activity against deoxycytidine followed by deadenosine and deoxyguanosine . Shows only very minor activity against deoxyuridine and deoxythymidine .<BOP> | A0A1L8HV70 |
Q6X893 | CTL1_MOUSE | Solute carrier family 44 member 1 | Mus | <M><G><C><C><S><S><A><S><A><A><Q><S><S><K><R><E><W><K><P><L><E><D><R><S><C><T><D><I><P><W><L><L><L><F><V><L><F><C><I><G><M><G><F><I><C><G><F><S><V><A><T><G><A><A><A><R><L><V><S><G><Y><D><S><Y><G><N><I><C><G><Q><R><N><A><K><L><E><A><I><P><N><S><G><L><D><H><T><H><R><K><Y><V><F><F><L><D><P><C><N><L><D><L><I><N><R><K><I><K... | Choline transporter. May be involved in membrane synthesis and myelin production.<BOP> | Q6X893 |
A6TUB2 | MNMA_ALKMQ | tRNA-specific 2-thiouridylase MnmA | Alkaliphilus | <M><K><K><D><P><K><D><T><K><V><V><I><G><M><S><G><G><V><D><S><S><V><A><A><L><K><L><K><E><Q><G><Y><D><V><I><G><I><F><M><K><N><W><D><E><P><D><E><Y><G><Y><C><T><A><A><E><D><Y><E><D><V><R><R><V><C><E><Q><I><G><I><P><Y><Y><T><V><N><F><E><K><E><Y><W><E><K><V><F><Q><Y><F><L><D><E><Y><K><K><G><R><T><P><N><P><D><V><M><C><N><K><E... | Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.<BOP> | A6TUB2 |
Q32RY5 | YCF3_STAPU | Photosystem I assembly protein Ycf3 | Staurastrum | <M><P><R><S><Q><R><N><D><N><F><I><D><K><T><F><T><I><V><A><D><I><L><L><R><I><I><P><T><T><Q><R><E><K><E><A><F><T><Y><Y><R><D><G><M><S><A><Q><S><E><G><E><Y><A><E><A><L><L><N><Y><Y><E><A><M><R><L><E><I><D><P><Y><D><R><S><Y><I><L><Y><N><I><G><L><I><H><T><S><N><G><E><H><V><K><A><L><E><Y><Y><F><Q><A><L><E><R><N><P><S><L><P><Q... | Essential for the assembly of the photosystem I (PSI) complex. May act as a chaperone-like factor to guide the assembly of the PSI subunits.<BOP> | Q32RY5 |
Q0VPJ1 | ACCD_ALCBS | Acetyl-coenzyme A carboxylase carboxyl transferase subunit beta | Alcanivorax | <M><S><N><S><N><W><L><E><K><I><L><P><A><V><R><R><P><Q><E><S><R><R><N><N><I><P><E><G><L><W><R><K><C><P><R><C><E><G><V><V><Y><R><P><E><L><D><R><N><M><D><V><C><P><K><C><D><H><H><L><R><I><S><A><R><R><R><L><K><L><F><L><D><E><G><V><Q><T><E><I><G><T><E><L><S><P><V><D><R><L><K><F><K><D><S><K><K><Y><K><D><R><L><V><A><A><Q><K><A... | Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA.<BOP> | Q0VPJ1 |
O75496 | GEMI_HUMAN | Geminin | Homo | <M><N><P><S><M><K><Q><K><Q><E><E><I><K><E><N><I><K><N><S><S><V><P><R><R><T><L><K><M><I><Q><P><S><A><S><G><S><L><V><G><R><E><N><E><L><S><A><G><L><S><K><R><K><H><R><N><D><H><L><T><S><T><T><S><S><P><G><V><I><V><P><E><S><S><E><N><K><N><L><G><G><V><T><Q><E><S><F><D><L><M><I><K><E><N><P><S><S><Q><Y><W><K><E><V><A><E><K><R><R... | Inhibits DNA replication by preventing the incorporation of MCM complex into pre-replication complex (pre-RC) . It is degraded during the mitotic phase of the cell cycle . Its destruction at the metaphase-anaphase transition permits replication in the succeeding cell cycle . Inhibits histone acetyltransferase activity ... | O75496 |
A8LY49 | ARGC_SALAI | N-acetyl-glutamate semialdehyde dehydrogenase | Salinispora | <M><G><I><R><V><A><V><V><G><A><S><G><Y><A><G><G><E><L><L><R><L><V><A><G><H><P><E><F><E><L><V><T><A><T><A><H><S><Q><A><G><H><R><L><H><T><V><H><P><Q><L><I><G><L><D><L><V><L><A><E><T><D><P><A><A><L><A><D><A><D><L><V><F><L><A><L><P><H><G><E><S><A><A><L><A><A><Q><L><P><P><K><T><R><V><V><D><L><G><A><D><H><R><L><A><D><P><Y><A... | Catalyzes the NADPH-dependent reduction of N-acetyl-5-glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde.<BOP> | A8LY49 |
Q6FF10 | CRCB_ACIAD | Putative fluoride ion transporter CrcB | Acinetobacter | <M><Y><S><S><L><L><S><I><A><C><G><A><V><L><G><A><W><L><R><W><F><V><G><L><K><F><N><S><T><F><Q><N><F><P><L><G><T><I><L><V><N><L><V><G><G><F><I><I><G><F><A><I><A><L><F><A><N><M><Q><L><S><S><N><Y><K><L><F><V><I><T><G><F><C><G><A><L><T><T><F><S><T><F><S><A><E><V><I><D><L><L><Q><Q><Q><K><Y><G><F><A><I><A><L><I><T><I><H><L><M... | Important for reducing fluoride concentration in the cell, thus reducing its toxicity.<BOP> | Q6FF10 |
Q9ZMD9 | RL21_HELPJ | 50S ribosomal protein L21 | Helicobacter | <M><S><Y><A><I><F><K><H><G><G><K><Q><Y><K><V><V><E><G><D><I><V><L><L><D><K><M><N><K><E><P><K><A><L><V><E><L><V><E><V><L><A><V><S><K><E><G><K><L><S><C><G><K><P><F><V><N><G><A><K><I><E><A><E><V><I><N><E><G><R><S><K><K><V><I><T><F><K><K><R><R><R><K><D><S><K><T><K><R><G><F><R><R><D><F><T><R><V><R><I><T><K><I><V><A> | This protein binds to 23S rRNA in the presence of protein L20.<BOP> | Q9ZMD9 |
C5CG19 | FMT_KOSOT | Methionyl-tRNA formyltransferase | Kosmotoga | <M><K><I><V><F><M><G><T><P><D><F><A><A><E><H><L><R><K><L><V><E><K><K><Y><N><V><V><G><V><F><S><Q><P><D><K><P><K><G><R><G><K><K><L><I><P><T><P><V><K><Q><V><A><R><E><Y><G><I><P><V><F><Q><P><K><S><V><N><K><G><E><G><F><E><A><L><K><E><L><K><P><D><I><I><I><T><V><A><Y><G><K><L><L><K><Q><Q><V><F><E><L><P><P><L><G><C><Y><N><V><H... | Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.<BOP> | C5CG19 |
Q93Z53 | PKP3_ARATH | Pyruvate kinase isozyme B2, chloroplastic | Arabidopsis | <M><A><A><Y><G><Q><I><S><S><G><M><T><V><D><P><Q><V><L><S><S><S><R><N><I><G><V><S><L><S><P><L><R><R><T><L><I><G><A><G><V><R><S><T><S><I><S><L><R><Q><C><S><L><S><V><R><S><I><K><I><S><E><D><S><R><K><P><K><A><Y><A><E><N><G><A><F><D><V><G><V><L><D><S><S><S><Y><R><L><A><D><S><R><T><S><S><N><D><S><R><R><K><T><K><I><V><C><T><I... | Required for plastidial pyruvate kinase activity.<BOP> | Q93Z53 |
Q464W5 | CRCB3_METBF | Putative fluoride ion transporter CrcB 3 | Methanosarcina | <M><Y><T><I><L><L><V><G><I><G><G><F><I><G><A><T><L><R><Y><V><F><G><G><W><I><Q><N><S><F><V><N><F><P><V><G><T><L><T><I><N><T><I><G><S><F><F><L><G><L><I><M><Y><F><S><E><Y><Q><G><L><F><S><D><Q><T><R><I><F><L><T><I><G><I><L><G><A><F><T><T><L><S><T><F><G><Y><E><S><F><R><L><L><D><D><S><K><L><M><L><M><S><I><N><V><V><S><T><V><L... | Important for reducing fluoride concentration in the cell, thus reducing its toxicity.<BOP> | Q464W5 |
A4QCD6 | SSRP_CORGB | Small protein B | Corynebacterium | <M><A><K><K><K><K><K><V><D><E><N><N><S><V><L><A><T><N><R><K><A><R><H><D><Y><H><I><I><D><T><W><E><A><G><V><V><L><L><G><T><E><I><K><S><L><R><E><G><K><V><S><L><V><D><S><F><A><T><I><D><N><G><E><I><W><L><Q><H><L><H><I><P><Q><Y><S><M><G><S><W><T><N><H><T><P><K><R><T><R><K><L><L><L><H><R><N><E><I><D><S><L><M><G><K><V><R><D><G... | Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemb... | A4QCD6 |
Q8GBD3 | CH10_ACEP3 | Chaperonin-10 | Acetobacter | <M><T><K><F><R><P><L><H><D><R><V><V><V><R><R><L><E><G><E><Q><K><T><A><G><G><I><I><I><P><D><T><A><Q><E><K><P><M><E><G><E><V><V><A><V><G><P><G><A><R><N><E><Q><G><Q><I><V><A><L><D><V><K><A><G><D><R><V><L><F><G><K><W><S><G><T><E><V><K><I><D><G><E><E><L><L><I><M><K><E><S><D><I><M><G><V><V><T><A> | Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of ... | Q8GBD3 |
Q6Q972 | PCB_PRODI | Chlorophyll a/b light-harvesting protein Pcb | Prochloron | <M><G><M><Q><T><Y><G><N><P><D><V><E><Y><G><W><W><A><G><N><S><R><L><A><G><F><S><G><K><W><L><A><A><H><V><A><Q><A><A><L><I><V><F><W><A><G><A><I><C><L><F><E><V><A><R><Y><T><A><D><V><P><L><G><E><Q><N><L><I><L><I><P><H><M><A><S><L><G><L><G><I><G><E><G><G><Q><I><V><D><T><F><P><Y><F><A><V><G><V><V><H><L><V><S><S><A><V><I><G><A... | The antenna complex functions as a light receptor, it captures and delivers excitation energy to photosystem II (PSII). The Prochlorales pcb genes are not related to higher plant LHCs.<BOP> | Q6Q972 |
B0TLB5 | TUSA_SHEHH | Sulfur carrier protein TusA | Shewanella | <M><N><D><Q><F><S><A><A><Q><H><Q><L><D><A><L><G><L><R><C><P><E><P><V><M><M><V><R><K><S><V><R><R><M><N><D><G><E><T><L><L><I><I><A><D><D><P><A><T><T><R><D><I><P><S><F><C><E><F><M><D><H><T><L><I><A><S><Q><T><E><S><T><P><Y><Q><Y><L><I><K><K><G><L> | Sulfur carrier protein which probably makes part of a sulfur-relay system.<BOP> | B0TLB5 |
Q9HIQ4 | THIE_THEAC | Thiamine-phosphate pyrophosphorylase | Thermoplasma | <M><K><L><E><G><R><R><I><K><G><L><Y><L><V><T><E><D><Y><S><R><K><N><F><F><N><I><I><E><E><A><I><I><G><G><V><D><I><V><Q><Y><R><D><K><S><N><P><R><S><V><R><L><D><V><A><R><K><V><K><Q><I><C><N><R><Y><D><I><L><F><F><I><D><D><D><V><Q><L><A><I><E><V><Q><A><D><G><V><H><I><G><K><D><D><M><P><L><P><D><A><R><R><I><F><D><G><L><I><G><Y... | Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP).<BOP> | Q9HIQ4 |
Q4JAB4 | CDC62_SULAC | ORC1-type DNA replication protein 2 | Sulfolobus | <M><D><D><I><K><N><L><I><E><D><L><L><G><G><D><T><V><F><N><N><T><K><I><L><N><P><E><Y><I><P><S><N><L><P><H><R><E><N><Q><I><K><E><M><T><V><S><F><R><D><L><I><L><N><P><G><S><S><S><I><R><L><V><I><I><G><R><T><G><T><G><K><S><V><T><T><K><K><F><G><L><K><L><R><E><I><A><H><E><R><N><L><R><L><E><Y><V><H><V><N><C><H><R><Q><R><T><L><Y... | Involved in regulation of DNA replication.<BOP> | Q4JAB4 |
B6JDC7 | ATPF1_AFIC5 | F-type ATPase subunit b 1 | Afipia | <M><L><H><E><A><E><T><W><V><A><V><A><F><V><L><M><V><A><L><F><I><Y><F><G><A><H><R><M><I><G><E><A><L><D><R><R><S><A><R><I><R><K><E><L><D><D><A><R><Q><L><K><E><E><A><Q><K><L><V><A><E><Y><R><S><R><R><E><S><A><E><R><E><A><Q><E><I><V><A><A><A><Q><A><D><A><E><R><I><A><Q><E><A><K><A><K><M><E><D><F><V><A><R><R><T><K><A><A><E><S... | Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0).<BOP> | B6JDC7 |
B3QZW0 | RS4_PHYMT | 30S ribosomal protein S4 | 16SrX (Apple proliferation group) | <M><S><R><Y><T><G><S><I><W><K><V><S><R><R><L><N><Y><S><L><S><E><T><G><K><E><L><I><K><R><P><Y><A><P><G><M><H><G><K><K><R><I><K><A><K><D><Y><G><L><Q><L><Q><E><K><Q><K><V><R><F><T><Y><G><I><S><E><K><Q><F><K><K><I><F><K><D><A><G><K><L><K><G><I><H><G><E><M><F><L><F><L><L><E><S><R><L><D><N><V><V><Y><R><L><G><F><A><K><T><R><Q... | With S5 and S12 plays an important role in translational accuracy.<BOP> | B3QZW0 |
Q5R146 | THIG_IDILO | Thiazole synthase | Idiomarina | <M><L><R><I><A><D><R><D><F><H><S><R><L><F><I><G><S><G><K><Y><S><S><A><D><I><M><Q><K><S><L><A><A><S><G><S><E><L><V><T><L><A><L><K><R><V><E><L><E><R><P><T><D><D><I><V><T><P><I><Q><N><L><G><L><Q><L><L><P><N><T><S><G><A><K><T><A><Q><D><A><I><F><A><A><R><L><A><R><E><A><L><G><T><H><W><L><K><L><E><I><H><P><D><P><N><Y><L><L><P... | Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S.<BOP> | Q5R146 |
P40358 | JEM1_YEAST | DnaJ-like protein of the ER membrane 1 | Saccharomyces | <M><I><L><I><S><G><Y><C><L><L><V><Y><S><V><I><L><P><V><L><I><S><A><S><K><L><C><D><L><A><E><L><Q><R><L><N><K><N><L><K><V><D><T><E><S><L><P><K><Y><Q><W><I><A><G><Q><L><E><Q><N><C><M><T><A><D><P><A><S><E><N><M><S><D><V><I><Q><L><A><N><Q><I><Y><Y><K><I><G><L><I><Q><L><S><N><D><Q><H><L><R><A><I><N><T><F><E><K><I><V><F><N><E... | Acts as a DnaJ-like chaperone required for nuclear membrane fusion during mating.<BOP> | P40358 |
O12988 | CRYAA_COLLI | Alpha-crystallin A chain | Columba | <R><A><L><G><P><L><I><P><S><R><L><F><D><Q><F><F><G><E><G><L><L><E><Y><D><L><L><P><W><F><S><S><T><I><S><P><Y><Y><R><Q><S><L><F><R><S><V><L><E><S><G><I><S><E><V><R><S><D><R><E><K><F><T><I><M><L><D><V><K><H><F><S><P><E><D><L><S><V><K><I><I><D><D><F><V><E><I><H><G><K><H><S><E><R><Q><D><D><H><G><Y><I><S><R><E><F><H><R><R><Y... | Contributes to the transparency and refractive index of the lens. May act as a chaperone, preventing aggregation of various proteins under a wide range of stress conditions.<BOP> | O12988 |
Q05509 | GLME_CLOTT | Methylaspartate mutase | Clostridium | <M><E><L><K><N><K><K><W><T><D><E><E><F><F><K><Q><R><E><E><V><L><K><Q><W><P><T><G><K><E><V><D><L><Q><E><A><V><D><Y><L><K><K><V><P><T><E><K><N><F><A><D><K><L><V><R><A><K><E><A><G><I><T><L><A><Q><P><R><A><G><V><A><L><L><D><E><H><I><N><L><L><R><Y><L><Q><D><E><G><G><A><D><L><L><P><S><T><I><D><A><Y><T><R><Q><N><R><Y><E><E><C... | Catalyzes the carbon skeleton rearrangement of L-glutamate to L-threo-3-methylaspartate ((2S,3S)-3-methylaspartate).<BOP> | Q05509 |
Q54X03 | PMM1_DICDI | Phosphomannomutase 1 | Dictyostelium | <M><S><L><V><P><N><T><I><C><L><F><D><V><D><G><T><L><T><K><P><R><N><V><I><T><P><E><M><K><D><F><L><A><G><L><R><T><K><V><E><L><G><V><V><G><G><S><D><I><N><K><I><K><E><Q><L><G><E><N><C><I><N><E><F><H><Y><L><F><A><E><N><G><L><L><S><F><K><D><G><S><L><L><A><T><Q><D><I><K><K><F><L><G><E><E><N><I><K><K><F><I><N><F><V><L><H><Y><I... | Involved in the synthesis of the GDP-mannose and dolichol-phosphate-mannose required for a number of critical mannosyl transfer reactions.<BOP> | Q54X03 |
Q54P59 | SARAF_DICDI | Transmembrane protein 66 | Dictyostelium | <M><K><H><N><Y><Y><I><L><F><L><I><L><I><S><S><L><F><L><S><N><K><V><V><E><S><Y><G><H><R><N><N><N><K><G><G><D><S><K><I><L><L><K><D><V><Q><V><L><T><L><R><S><G><E><M><T><K><A><R><R><S><S><P><I><Q><Q><M><E><C><I><G><G><T><A><T><K><E><L><E><L><Y><P><K><T><I><Q><C><Y><N><M><G><S><N><G><V><D><V><Q><W><K><C><E><A><T><L><D><S><T... | Negative regulator of store-operated Ca(2+) entry (SOCE) involved in protecting cells from Ca(2+) overfilling.<BOP> | Q54P59 |
Q5HMA8 | PTPB_STAEQ | Phosphotyrosine phosphatase B | Staphylococcus | <M><K><I><I><F><V><C><S><G><N><T><C><R><S><P><L><A><E><S><I><A><K><S><L><L><P><H><D><S><I><A><S><R><G><L><F><A><V><E><G><Q><A><I><S><K><E><S><L><E><L><I><H><K><Y><D><L><P><E><P><S><R><A><Q><A><F><H><I><D><D><L><D><A><D><I><I><L><T><M><T><Q><A><H><K><D><L><I><F><S><M><Y><G><R><Q><S><N><V><F><T><L><N><E><Y><V><G><D><T><Q... | Dephosphorylates the phosphotyrosine-containing proteins.<BOP> | Q5HMA8 |
Q99004 | AMELY_BOVIN | Class II amelogenin | Bos | <M><G><T><W><I><L><F><A><C><L><L><G><A><A><Y><S><M><P><L><P><P><H><P><G><H><P><G><Y><I><N><F><S><Y><E><V><L><T><P><L><K><W><Y><Q><N><M><L><R><Y><P><Y><P><S><Y><G><Y><E><P><V><G><G><W><L><H><H><Q><I><I><P><V><V><S><Q><Q><S><P><Q><N><H><A><L><Q><P><H><H><H><N><P><M><V><P><A><Q><Q><P><V><V><P><Q><Q><P><M><M><P><V><P><G><Q... | Plays a role in the biomineralization of teeth. Seems to regulate the formation of crystallites during the secretory stage of tooth enamel development. Thought to play a major role in the structural organization and mineralization of developing enamel.<BOP> | Q99004 |
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