accession
stringlengths
6
10
name
stringlengths
6
11
Full Name
stringlengths
1
147
⌀
taxon
stringlengths
3
46
⌀
sequence
stringlengths
48
2.3k
function
stringlengths
11
1.34k
AlphaFoldDB
stringlengths
6
10
B7GYS7
LEPA_ACIB3
Ribosomal back-translocase LepA
Acinetobacter calcoaceticus/baumannii complex
<M><A><Q><A><K><K><S><V><D><I><K><N><I><R><N><F><S><I><I><A><H><I><D><H><G><K><S><T><L><A><D><R><F><I><Q><M><C><G><G><L><Q><D><R><E><M><Q><A><Q><V><L><D><S><M><E><L><E><R><E><R><G><I><T><I><K><A><A><S><V><T><L><Y><Y><T><H><P><N><G><Q><E><Y><Q><L><N><F><I><D><T><P><G><H><V><D><F><S><Y><E><V><S><R><S><L><A><A><C><E><G><A...
Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre-t...
B7GYS7
Q9WYZ2
HSLU_THEMA
Unfoldase HslU
Thermotoga
<M><K><S><F><D><E><M><T><P><K><E><I><V><Q><E><L><D><K><Y><I><V><G><Q><Y><E><A><K><K><A><V><A><I><A><V><R><N><R><I><R><R><Q><K><L><P><E><E><W><R><K><E><V><L><P><K><N><I><L><M><I><G><P><T><G><V><G><K><T><E><I><A><R><R><L><A><Q><L><S><G><S><P><F><L><K><V><E><A><T><R><F><T><E><V><G><Y><V><G><K><N><V><D><S><M><I><R><D><L><V...
ATPase subunit of a proteasome-like degradation complex; this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before...
Q9WYZ2
Q5F678
QUEF_NEIG1
PreQ(0) reductase
Neisseria
<M><S><R><N><N><E><E><L><Q><G><I><S><L><L><G><N><Q><K><T><Q><Y><P><T><G><Y><A><P><E><I><L><E><A><F><D><N><K><H><P><D><N><D><Y><F><V><K><F><V><C><P><E><F><T><S><L><C><P><M><T><G><Q><P><D><F><A><T><I><V><I><R><Y><I><P><H><I><K><M><V><E><S><K><S><L><K><L><Y><L><F><S><F><R><N><H><G><D><F><H><E><D><C><V><N><I><I><M><K><D><L...
Catalyzes the NADPH-dependent reduction of 7-cyano-7-deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1).<BOP>
Q5F678
B5ZSU2
PDXH_RHILW
Pyridoxal 5'-phosphate synthase
Rhizobium
<M><S><A><N><E><L><T><S><G><D><F><T><E><S><G><E><P><F><K><L><F><A><E><W><L><G><E><A><E><A><S><E><P><N><D><P><N><A><V><A><L><A><T><V><D><E><D><G><L><P><N><V><R><M><V><L><L><K><G><F><D><D><N><G><F><V><F><Y><T><N><F><E><S><Q><K><G><R><E><I><L><G><Q><K><K><A><A><M><C><F><H><W><K><S><L><R><R><Q><V><R><L><R><G><P><V><E><I><V...
Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP).<BOP>
B5ZSU2
Q8CNC7
UREF_STAES
null
Staphylococcus
<M><I><D><H><Q><H><L><R><L><F><Q><F><C><D><S><Q><F><P><T><G><A><F><S><H><S><F><G><L><E><T><Y><I><Q><R><E><T><V><H><D><T><E><T><F><I><K><W><L><H><L><F><I><N><E><Q><L><T><Y><S><D><G><I><A><M><R><I><V><Y><H><A><L><I><N><N><D><K><D><K><I><L><D><I><N><Q><K><L><F><V><Q><N><L><P><K><E><T><R><I><G><A><K><Q><M><G><T><R><M><V><K...
Required for maturation of urease via the functional incorporation of the urease nickel metallocenter.<BOP>
Q8CNC7
Q864H9
MSHR_MICAD
Melanocortin receptor 1
Mico
<M><P><M><Q><G><A><Q><R><K><L><L><G><S><L><N><S><T><P><T><A><T><S><N><L><G><L><A><A><N><H><T><G><A><P><C><L><E><V><S><I><P><D><G><L><F><L><S><L><G><L><V><S><L><V><E><N><V><L><V><V><A><A><I><A><K><N><R><N><L><H><S><S><M><Y><C><F><I><C><C><L><A><L><S><D><L><L><V><S><G><S><N><M><L><E><T><A><I><I><L><L><L><E><A><G><T><L><A...
Receptor for MSH (alpha, beta and gamma) and ACTH. The activity of this receptor is mediated by G proteins which activate adenylate cyclase. Mediates melanogenesis, the production of eumelanin (black/brown) and phaeomelanin (red/yellow), via regulation of cAMP signaling in melanocytes.<BOP>
Q864H9
Q9L7S0
SQUU_SALTY
3-sulfolactaldehyde reductase
Salmonella
<M><A><V><I><A><F><I><G><L><G><Q><M><G><S><P><M><A><S><N><L><L><K><Q><G><H><Q><L><S><V><F><D><V><N><P><D><A><V><Q><R><L><V><D><K><G><A><Q><P><A><S><S><P><A><Q><A><T><I><G><A><E><F><V><I><T><M><L><P><N><G><D><L><V><R><S><V><L><F><G><E><Q><G><V><C><E><T><L><S><R><E><A><L><V><I><D><M><S><T><I><H><P><L><Q><T><D><N><L><I><A...
Reduces 3-sulfolactaldehyde (SLA) to 2,3-dihydroxypropane 1-sulfonate (DHPS).<BOP>
Q9L7S0
Q64FU1
IL23A_HORSE
Interleukin-23 subunit p19
Equus
<M><L><G><S><R><A><V><L><L><L><L><L><L><L><W><P><R><T><A><Q><A><R><A><V><P><G><G><S><S><P><A><W><A><Q><C><Q><Q><L><S><Q><K><L><C><T><L><A><W><S><A><H><P><P><M><G><H><V><D><L><P><R><E><E><G><D><A><E><T><T><N><D><V><P><H><I><Q><C><E><D><G><C><D><P><E><G><L><R><D><N><S><Q><P><C><L><Q><R><I><H><Q><G><L><V><F><Y><E><K><L><L...
Associates with IL12B to form the pro-inflammatory cytokine IL-23 that plays different roles in innate and adaptive immunity. Released by antigen-presenting cells such as dendritic cells or macrophages, binds to a heterodimeric receptor complex composed of IL12RB1 and IL23R to activate JAK2 and TYK2 which then phosphor...
Q64FU1
Q30KK1
DB127_PANTR
Defensin, beta 127
Pan
<M><G><L><F><M><I><I><A><I><L><L><F><Q><K><P><T><V><T><E><Q><L><K><K><C><W><N><N><Y><V><Q><G><H><C><R><K><I><C><R><V><N><E><V><P><E><A><L><C><E><N><G><R><Y><C><C><L><N><I><K><E><L><E><A><C><K><K><I><T><K><P><S><H><P><K><P><A><T><L><A><L><T><L><Q><D><Y><V><T><I><I><E><N><F><P><S><L><K><T><Q><S><T>
Has antibacterial activity.<BOP>
Q30KK1
Q0I5A5
IOLE_HAES1
2-keto-myo-inositol dehydratase
Histophilus
<M><K><A><E><N><V><K><L><G><I><A><P><I><G><W><T><N><D><D><L><P><E><I><G><K><E><N><T><F><E><Q><C><V><S><E><M><A><L><A><G><F><T><G><S><E><V><G><S><K><Y><P><R><D><I><D><V><L><K><R><K><L><D><L><R><G><I><Q><I><C><N><A><W><F><S><T><F><F><V><D><G><K><K><E><E><T><I><K><G><F><I><E><H><R><D><F><L><H><A><M><G><A><K><V><I><G><C><S...
Catalyzes the dehydration of inosose (2-keto-myo-inositol, 2KMI or 2,4,6/3,5-pentahydroxycyclohexanone) to 3D-(3,5/4)-trihydroxycyclohexane-1,2-dione (D-2,3-diketo-4-deoxy-epi-inositol).<BOP>
Q0I5A5
Q58868
METE_METJA
Methylcobalamin:homocysteine methyltransferase
Methanocaldococcus
<M><I><T><T><V><V><G><S><Y><P><V><V><K><K><E><E><T><F><L><D><K><V><K><K><V><F><G><L><Y><D><E><Y><K><Y><A><I><E><R><A><V><K><D><Q><V><K><A><G><V><N><I><I><S><D><G><Q><V><R><G><D><M><V><E><I><F><T><N><N><M><Y><G><F><D><G><K><R><V><V><G><R><V><E><F><I><K><P><I><T><L><K><D><I><L><Y><A><K><S><I><A><K><K><L><N><P><N><V><E><I...
Catalyzes the transfer of a methyl group to L-homocysteine resulting in methionine formation. Can use methylcobalamin and methylcobinamide as methyl donors, but methylcobalamin is not considered to be the physiological substrate.<BOP>
Q58868
A7FGU1
RLMF_YERP3
rRNA adenine N-6-methyltransferase
Yersinia
<M><L><S><Y><A><P><E><N><A><Y><Q><R><A><S><T><M><E><N><K><K><V><F><P><K><E><K><S><G><L><H><P><R><N><R><H><R><S><R><Y><D><F><D><A><L><S><V><S><C><P><E><L><I><P><F><L><A><P><T><A><Y><G><D><I><S><V><D><F><A><D><P><L><A><V><K><M><L><N><K><A><L><L><K><H><F><Y><G><I><E><Y><W><D><I><P><A><D><S><L><C><P><P><I><P><G><R><A><D><Y...
Specifically methylates the adenine in position 1618 of 23S rRNA.<BOP>
A7FGU1
Q0AE34
RNH_NITEC
Ribonuclease H
Nitrosomonas
<M><Q><L><K><S><D><M><K><R><V><E><I><F><T><D><G><A><C><K><G><N><P><G><P><G><G><W><G><V><C><L><H><F><N><G><E><T><R><E><F><F><G><G><E><P><V><T><T><N><N><R><M><E><L><L><A><A><I><R><A><L><Q><E><L><E><S><L><E><D><N><G><Q><Q><H><L><Q><V><Q><L><H><T><D><S><Q><Y><V><Q><K><G><I><S><E><W><I><H><G><W><K><K><R><G><W><R><T><A><D><K...
Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.<BOP>
Q0AE34
A8GMB6
DAPB_RICAH
4-hydroxy-tetrahydrodipicolinate reductase
spotted fever group
<M><I><N><I><G><L><S><G><S><T><G><K><M><G><K><T><I><L><A><R><I><D><K><F><K><D><C><K><I><S><A><K><F><N><S><T><D><D><L><D><D><L><N><N><F><C><K><N><S><D><V><I><I><D><F><S><T><P><E><I><L><E><K><L><I><N><Y><A><L><K><H><N><T><K><L><V><I><G><T><T><G><L><Q><P><K><H><F><K><L><L><E><K><A><A><K><T><L><P><I><L><Y><S><A><N><M><S><T...
Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.<BOP>
A8GMB6
B3QH88
GLPK_RHOPT
Glycerokinase
Rhodopseudomonas
<M><P><F><V><M><A><I><D><Q><G><T><T><S><S><R><A><I><L><F><R><S><D><I><S><I><A><A><S><A><Q><Q><E><F><P><Q><H><F><P><A><S><G><W><V><E><H><E><P><E><D><I><W><A><T><T><I><A><T><C><R><A><A><M><D><K><A><G><A><T><A><A><D><I><A><A><I><G><I><T><N><Q><R><E><T><V><V><V><W><D><A><V><S><G><Q><A><I><H><R><A><I><V><W><Q><D><R><R><T><A...
Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn-glycerol 3-phosphate.<BOP>
B3QH88
A0T0B7
PETD_PHATC
17 kDa polypeptide
Phaeodactylum
<M><S><V><I><K><K><P><D><L><T><D><P><K><L><R><A><K><L><A><K><G><M><G><H><N><Y><Y><G><E><P><A><W><P><N><D><L><L><Y><V><F><P><L><T><M><L><G><T><L><T><C><I><V><G><L><S><V><L><A><P><T><Q><L><G><E><P><A><D><P><F><N><T><P><L><E><I><L><P><E><W><Y><F><F><P><T><F><N><L><L><R><V><L><P><N><K><L><L><G><V><L><A><M><A><A><V><P><L><G...
Component of the cytochrome b6-f complex, which mediates electron transfer between photosystem II (PSII) and photosystem I (PSI), cyclic electron flow around PSI, and state transitions.<BOP>
A0T0B7
Q7VI82
ACCA_HELHP
Acetyl-coenzyme A carboxylase carboxyl transferase subunit alpha
Helicobacter
<M><A><T><Y><L><D><F><E><Q><K><I><K><N><L><Q><D><D><I><E><S><A><I><I><S><G><D><N><D><A><I><S><I><L><E><K><E><L><E><K><E><V><S><S><V><Y><S><N><I><S><D><Y><Q><K><L><Q><L><A><R><H><P><D><R><P><Y><A><M><D><Y><I><E><S><I><L><K><N><P><Y><E><I><N><G><D><R><H><F><K><D><D><K><A><I><V><C><F><L><G><K><I><G><E><Q><T><T><M><I><I><G...
Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA.<BOP>
Q7VI82
A0A0S1TP26
C76H2_SALPM
Ferruginol monooxygenase
Salvia incertae sedis
<M><L><Q><L><G><S><Q><P><H><E><T><F><A><K><L><S><K><K><Y><G><P><L><M><S><I><H><L><G><S><L><Y><T><V><I><V><S><S><P><E><M><A><K><E><I><M><H><K><Y><G><Q><V><F><S><G><R><T><I><A><Q><A><V><H><A><C><D><H><D><K><I><S><M><G><F><L><P><V><G><A><E><W><R><D><M><R><K><I><C><K><E><Q><M><F><S><H><Q><S><M><E><D><S><Q><N><L><R><K><Q><K...
Monooxygenase involved in the biosynthesis of labdane-related diterpenes natural products . Catalyzes the oxidation of abietatriene to produce ferruginol . Ferruginol is an intermediate in the biosynthesis of carnosate, a potent antioxidant . May also convert miltiradiene into 11-oxomiltiradiene .<BOP>
A0A0S1TP26
B3PUN6
ACPS_RHIE6
4'-phosphopantetheinyl transferase AcpS
Rhizobium
<M><I><I><G><I><G><S><D><L><I><D><I><R><R><V><E><K><S><I><E><R><F><G><E><R><F><T><H><R><C><F><T><E><I><E><R><A><R><S><D><R><R><A><N><R><A><E><S><Y><A><K><R><F><A><A><K><E><A><C><S><K><A><L><G><T><G><L><A><Q><G><V><F><W><K><D><M><G><V><V><N><L><P><S><G><K><P><T><M><V><L><S><G><G><A><A><V><I><L><E><S><M><L><P><A><G><H><R...
Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein.<BOP>
B3PUN6
F4KAK5
PSD2_ARATH
Phosphatidylserine decarboxylase 2 alpha chain
Arabidopsis
<M><G><N><G><N><S><R><E><A><K><E><S><R><R><S><R><L><R><H><K><L><Q><K><F><R><I><H><R><R><H><L><R><S><S><R><N><S><A><G><M><V><I><Q><R><T><V><S><A><E><D><F><S><G><I><A><L><L><T><L><I><G><A><E><M><K><F><K><D><K><W><L><A><C><V><S><F><G><E><Q><T><F><R><T><E><I><S><D><T><T><Q><K><P><I><W><N><S><E><K><K><L><L><L><E><K><N><G><P...
Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer). Plays a central role in phospholipid metabolism and in the interorganelle trafficking of phosphatidylserine. Contributes only to a minor proportion of PtdEtn production.<BOP>
F4KAK5
Q3SLN3
RL18_THIDA
50S ribosomal protein L18
Thiobacillus
<M><N><T><K><Q><S><R><I><R><R><A><R><K><T><R><A><K><I><A><A><V><K><A><I><R><L><A><I><H><R><T><N><S><H><I><Y><A><Q><I><I><S><A><D><G><G><T><V><M><A><S><A><S><S><N><D><K><D><L><R><G><Q><L><A><N><G><G><T><T><A><A><A><A><A><V><G><K><R><L><A><E><K><A><K><G><L><G><I><E><K><V><A><F><D><R><A><G><F><K><F><H><G><R><V><K><A><L><A...
This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.<BOP>
Q3SLN3
A1USL8
RS19_BARBK
30S ribosomal protein S19
Bartonella
<M><V><R><S><V><W><K><G><P><F><V><D><G><Y><L><L><G><K><A><E><K><V><R><A><S><G><R><N><E><V><I><K><I><W><S><R><R><S><T><I><L><P><Q><F><V><G><L><T><F><G><V><H><N><G><N><K><H><I><P><V><F><V><S><E><E><M><V><G><H><K><F><G><E><F><A><P><T><R><T><Y><Y><G><H><G><A><D><K><K><A><K><R><K>
Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.<BOP>
A1USL8
Q91WN4
KMO_MOUSE
Kynurenine 3-hydroxylase
Mus
<M><A><S><S><D><T><Q><G><K><R><V><A><V><I><G><G><G><L><V><G><A><L><N><A><C><F><L><A><K><R><N><F><Q><V><D><V><Y><E><A><R><E><D><I><R><V><A><K><S><A><R><G><R><S><I><N><L><A><L><S><Y><R><G><R><Q><A><L><K><A><I><G><L><E><D><Q><I><V><S><K><G><V><P><M><K><A><R><M><I><H><S><L><S><G><K><K><S><A><I><P><Y><G><N><K><S><Q><Y><I><L...
Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid, a neurotoxic NMDA receptor antagonist and potential endogenous inhibitor of NMDA receptor signaling in axonal targeting, synaptogenesis and apoptosis during brain development. Quinol...
Q91WN4
Q07PK4
MIAA_RHOP5
Isopentenyl-diphosphate:tRNA isopentenyltransferase
Rhodopseudomonas
<M><S><V><A><T><S><D><M><S><G><A><G><P><E><Q><A><K><A><V><L><I><A><G><P><T><A><S><G><K><S><A><L><A><L><R><L><A><E><A><R><G><G><V><V><I><N><T><D><S><M><Q><V><Y><R><D><L><R><V><L><T><A><R><P><T><P><D><E><E><A><R><A><P><H><R><L><Y><G><T><V><D><A><A><Q><N><F><S><A><G><A><W><L><D><A><A><A><G><A><L><A><E><A><R><R><A><G><A><M...
Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).<BOP>
Q07PK4
B9E748
TIG_MACCJ
PPIase
Macrococcus
<M><S><V><K><W><E><K><Q><E><G><N><E><G><V><L><T><V><T><V><P><A><E><E><V><N><A><G><L><D><K><A><F><K><K><V><V><K><Q><V><N><V><P><G><F><R><K><G><K><M><P><R><P><M><F><E><Q><R><F><G><V><E><A><L><Y><Q><D><A><L><D><F><I><L><P><D><A><Y><A><A><A><V><E><E><A><G><I><N><P><V><D><R><P><E><I><D><I><E><Q><M><E><K><G><K><E><L><I><F><T...
Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase.<BOP>
B9E748
B0SZ20
EFTS_CAUSK
Elongation factor Ts
unclassified Caulobacter
<M><A><E><V><T><A><A><L><V><K><E><L><R><E><K><S><G><V><G><M><M><D><C><K><K><A><L><V><E><N><N><G><D><I><D><A><S><I><D><W><L><R><A><K><G><L><S><K><A><A><K><K><A><D><R><V><A><A><E><G><L><V><G><I><V><V><R><A><E><G><A><G><M><I><A><A><A><V><E><V><N><A><E><T><D><F><L><S><R><N><E><L><F><Q><T><A><V><R><K><I><A><R><A><G><L><D><N...
Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome.<BOP>
B0SZ20
Q44015
YGB4_CUPNE
Glyoxylate-induced protein
Cupriavidus
<M><P><R><F><A><A><N><L><S><M><M><Y><N><E><H><A><F><L><D><R><F><A><A><A><A><A><D><G><F><R><A><V><E><F><L><F><P><Y><E><H><A><A><A><E><L><R><A><R><L><D><A><N><G><L><T><Q><A><L><F><N><A><A><P><G><D><W><A><A><G><E><R><G><L><A><A><L><P><G><R><E><A><D><F><R><G><T><I><G><R><A><L><E><Y><A><G><V><I><G><N><D><R><I><H><V><M><A><G...
Catalyzes the reversible isomerization between hydroxypyruvate and 2-hydroxy-3-oxopropanoate (also termed tartronate semialdehyde).<BOP>
Q44015
Q03KS5
PYRE_STRTD
Orotate phosphoribosyltransferase
Streptococcus
<M><T><L><A><S><Q><I><A><S><D><L><L><D><I><K><A><V><Y><L><K><P><E><E><P><F><T><W><A><S><G><I><K><S><P><I><Y><T><D><N><R><I><T><L><S><Y><P><E><T><R><T><L><I><E><N><G><F><V><K><K><I><K><E><E><F><P><E><V><E><V><I><A><G><T><A><T><A><G><I><P><H><G><A><I><I><A><D><K><M><N><L><P><F><A><Y><I><R><S><K><P><K><D><H><G><A><G><N><Q...
Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).<BOP>
Q03KS5
A5EXW8
RPOZ_DICNV
Transcriptase subunit omega
Dichelobacter
<M><A><R><V><T><V><E><D><C><L><I><H><E><N><S><R><F><R><L><V><L><A><A><S><K><R><A><R><Q><L><T><L><G><H><Q><P><L><V><A><P><E><N><D><K><P><T><V><L><A><L><R><E><I><E><E><G><K><V><T><V><Q><G><L><L><D><G><Q><D><V><S><E><H><L><A><R><Q><A>
Promotes RNA polymerase assembly. Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.<BOP>
A5EXW8
Q27896
TRF_DROME
TBP-related factor
Sophophora
<M><Q><F><H><F><K><V><A><D><A><E><R><D><R><D><N><V><A><A><T><S><N><A><A><A><N><P><H><A><A><L><Q><P><Q><Q><P><V><A><L><V><E><P><K><D><A><Q><H><E><I><R><L><Q><N><I><V><A><T><F><S><V><N><C><E><L><D><L><K><A><I><N><S><R><T><R><N><S><E><Y><S><P><K><R><F><R><G><V><I><M><R><M><H><S><P><R><C><T><A><L><I><F><R><T><G><K><V><I><C...
May be essential for embryonic development.<BOP>
Q27896
Q12J93
MUTL_SHEDO
DNA mismatch repair protein MutL
Shewanella
<M><P><I><H><I><L><P><P><Q><L><A><N><Q><I><A><A><G><E><V><V><E><R><P><A><S><V><V><K><E><L><V><E><N><S><L><D><A><G><A><T><R><V><D><I><D><I><D><K><G><G><S><K><L><I><R><I><R><D><N><G><S><G><I><P><K><D><E><L><A><L><A><L><S><R><H><A><T><S><K><V><H><S><L><D><D><L><E><A><I><L><S><F><G><F><R><G><E><A><L><A><S><I><S><S><V><A><R...
This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part ...
Q12J93
P0CT93
ORDA_ASPFL
Cytochrome P450 64
Aspergillus subgen. Circumdati
<M><I><Y><S><I><I><I><C><A><G><A><L><L><G><L><W><I><L><E><K><L><L><A><P><K><D><T><R><P><P><L><P><P><G><P><W><R><K><P><I><I><G><N><L><T><D><F><P><P><K><G><T><P><E><W><L><F><W><A><K><H><Q><E><R><Y><G><P><M><S><S><L><E><V><M><G><Q><T><I><I><M><I><N><D><A><Q><L><G><I><E><I><M><H><K><K><S><A><L><S><Q><M><I><P><D><A><P><F><A...
Converts O-methylsterigmatocystin (OMST) to aflatoxin B1 and converts dihydro-O-methylsterigmatocystin (DHOMST) to aflatoxin B2 in the aflatoxin biosynthesis pathway.<BOP>
P0CT93
Q48544
PEPR_LACDL
HTH-type transcriptional regulator pepR1
Lactobacillus
<M><N><K><Q><D><V><T><I><Y><D><V><A><R><E><A><K><V><S><M><A><T><V><S><R><V><V><N><G><N><N><N><V><R><K><E><T><R><D><R><V><M><E><V><I><K><R><L><H><Y><Q><P><N><A><V><A><Q><G><L><A><S><K><R><T><T><T><V><G><L><I><V><P><D><L><T><N><L><Y><F><A><E><L><S><K><G><I><D><D><I><A><V><L><Y><K><Y><N><I><I><I><S><S><V><E><N><R><L><M><K...
Transcriptional regulator of the pepQ gene for prolidase.<BOP>
Q48544
P07143
CY1_YEAST
Ubiquinol-cytochrome c oxidoreductase cytochrome c1 subunit
Saccharomyces
<M><F><S><N><L><S><K><R><W><A><Q><R><T><L><S><K><S><F><Y><S><T><A><T><G><A><A><S><K><S><G><K><L><T><Q><K><L><V><T><A><G><V><A><A><A><G><I><T><A><S><T><L><L><Y><A><D><S><L><T><A><E><A><M><T><A><A><E><H><G><L><H><A><P><A><Y><A><W><S><H><N><G><P><F><E><T><F><D><H><A><S><I><R><R><G><Y><Q><V><Y><R><E><V><C><A><A><C><H><S><L...
Component of the ubiquinol-cytochrome c oxidoreductase, a multisubunit transmembrane complex that is part of the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidor...
P07143
B4F766
DYM_RAT
Dymeclin
Rattus
<M><G><S><N><S><S><K><I><S><D><L><P><K><N><E><Y><L><K><R><L><S><G><P><E><A><I><S><E><N><D><P><F><W><N><Q><L><F><S><F><S><F><S><A><P><T><S><S><T><E><L><K><L><L><E><E><A><T><I><S><V><C><K><S><L><V><E><N><N><P><R><T><G><N><L><A><A><L><T><K><V><F><L><A><R><T><R><E><L><R><L><S><A><E><C><Q><N><H><I><F><I><W><Q><T><H><N><A><L...
Necessary for correct organization of Golgi apparatus. Involved in bone development.<BOP>
B4F766
Q5RDV8
METL6_PONAB
Methyltransferase-like protein 6
Pongo
<M><A><S><L><Q><R><K><G><L><Q><A><R><I><L><T><S><E><E><E><E><K><L><K><R><D><Q><T><L><V><S><D><F><K><Q><Q><K><L><E><Q><E><A><Q><K><N><W><D><L><F><Y><K><R><N><S><T><N><F><F><K><D><R><H><W><T><T><R><E><F><E><E><L><R><S><C><R><E><F><E><D><Q><K><L><T><M><L><E><A><G><R><G><V><G><N><C><L><F><P><L><L><E><E><D><P><N><I><F><A><Y...
S-adenosyl-L-methionine-dependent methyltransferase that mediates N(3)-methylcytidine modification of residue 32 of the tRNA anticodon loop of tRNA(Ser), including tRNA(Ser)(UGA) and tRNA(Ser)(GCU). Interaction with SARS1/SerRS is required for N(3)-methylcytidine methylation.<BOP>
Q5RDV8
Q9CW73
B3GA1_MOUSE
UDP-GlcUA:glycoprotein beta-1,3-glucuronyltransferase
Mus
<M><P><K><R><R><D><I><L><A><I><V><L><I><V><L><P><W><T><L><L><I><T><V><W><H><Q><S><S><L><A><P><L><L><A><V><H><K><D><E><G><S><D><P><R><H><E><A><P><P><G><A><D><P><R><E><Y><C><M><S><D><R><D><I><V><E><V><V><R><T><E><Y><V><Y><T><R><P><P><P><W><S><D><T><L><P><T><I><H><V><V><T><P><T><Y><S><R><P><V><Q><K><A><E><L><T><R><M><A><N...
Involved in the biosynthesis of L2/HNK-1 carbohydrate epitope on glycoproteins. Can also play a role in glycosaminoglycan biosynthesis. Substrates include asialo-orosomucoid (ASOR), asialo-fetuin, and asialo-neural cell adhesion molecule. Requires sphingomyelin for activity: stearoyl-sphingomyelin was the most effectiv...
Q9CW73
P46182
RL18_BUCAK
50S ribosomal protein L18
unclassified Buchnera (in: Bacteria)
<M><D><K><K><S><A><R><I><R><R><A><T><R><A><R><R><K><L><K><E><L><G><A><T><R><L><V><V><H><R><S><P><R><H><M><Y><A><Q><V><I><A><P><N><G><S><E><V><L><V><A><A><S><T><L><E><K><A><I><T><E><Q><L><K><Y><S><G><N><K><D><A><A><A><A><V><G><K><A><L><A><E><R><A><L><E><K><G><I><A><K><V><S><F><A><R><S><G><F><Q><Y><H><G><R><V><Q><A><L><A...
This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.<BOP>
P46182
Q32B99
AAEB_SHIDS
p-hydroxybenzoic acid efflux pump subunit AaeB
Shigella
<M><G><I><F><S><I><A><N><Q><H><I><R><F><A><V><K><L><A><T><A><I><V><L><A><L><F><V><G><F><H><F><Q><L><E><T><P><R><W><A><V><L><T><A><A><I><V><A><A><G><P><A><F><A><A><G><G><E><P><Y><S><G><A><I><R><Y><R><G><F><L><R><I><I><G><T><F><I><G><C><I><A><G><L><V><I><I><I><A><M><I><R><A><P><L><L><M><I><L><V><C><C><I><W><A><G><F><C><T...
Forms an efflux pump with AaeA. Could function as a metabolic relief valve, allowing to eliminate certain compounds when they accumulate to high levels in the cell.<BOP>
Q32B99
Q2RJT7
NUON_MOOTA
NDH-1 subunit N
Moorella
<M><A><N><L><H><L><L><T><V><E><I><L><T><A><A><L><G><L><G><L><L><A><L><G><L><L><V><P><H><S><D><R><R><G><I><A><Y><V><A><T><A><G><L><A><G><I><L><A><A><A><F><G><M><R><E><A><S><G><V><V><L><G><G><Y><V><I><D><P><F><G><T><Y><F><K><I><L><F><L><V><A><A><M><L><T><A><A><C><S><Y><D><Y><V><E><K><M><G><L><N><Q><G><E><Y><Y><A><L><L><V...
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions ar...
Q2RJT7
B2RHB7
GPMA_PORG3
2,3-bisphosphoglycerate-dependent phosphoglycerate mutase
Porphyromonas
<M><K><R><I><V><L><I><R><H><G><E><S><L><W><N><K><E><N><R><F><T><G><W><T><D><V><D><L><S><E><K><G><I><E><E><A><K><K><A><G><E><L><M><K><K><E><G><F><Q><F><T><K><A><Y><T><S><Y><L><K><R><A><V><K><T><L><N><G><V><L><D><V><M><D><L><D><W><I><P><V><E><K><T><W><R><L><N><E><K><H><Y><G><M><L><Q><G><L><N><K><A><E><T><A><E><K><Y><G><D...
Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.<BOP>
B2RHB7
Q9VEU6
GCYDA_DROME
Soluble guanylate cyclase 89Da
Sophophora
<M><Y><G><M><L><Y><E><S><V><Q><H><Y><V><Q><E><E><Y><G><V><D><I><W><R><K><V><C><H><I><I><D><C><K><H><N><S><F><K><T><H><Q><I><Y><P><D><K><L><M><P><D><I><A><E><A><L><S><A><C><T><G><E><S><F><D><F><C><M><N><F><F><G><R><C><F><V><R><F><F><S><N><F><G><Y><D><K><M><I><R><S><T><G><R><Y><F><C><D><F><L><Q><S><I><D><N><I><H><L><I><M...
Heterodimers with Gyc-89Da and Gyc-89Db are activated in response to changing oxygen concentrations, alerting flies to hypoxic environments. Under normal oxygen concentrations, oxygen binds to the heme group and results in low levels of guanylyl cyclase activity. When exposed to reduced oxygen concentrations, the oxyge...
Q9VEU6
P50433
GLYM_SOLTU
Serine methylase
Solanum
<M><A><M><A><I><A><L><R><R><L><S><A><T><V><D><K><P><V><K><S><L><Y><N><G><G><S><L><Y><Y><M><S><S><L><P><N><E><A><V><Y><D><K><E><K><S><G><V><A><W><P><K><Q><L><N><A><P><L><E><V><V><D><P><E><I><A><D><I><I><E><H><E><K><A><R><Q><W><K><G><L><E><L><I><P><S><E><N><F><T><S><V><S><V><M><Q><A><V><G><S><V><M><T><N><K><Y><S><E><G><Y...
Catalyzes the interconversion of serine and glycine.<BOP>
P50433
O34295
TTUC5_AGRVI
D-malate dehydrogenase [decarboxylating]
Agrobacterium
<M><R><E><Y><K><I><A><A><I><P><A><D><G><I><G><P><E><V><I><A><A><G><L><Q><V><L><E><A><L><E><Q><R><S><G><D><F><K><I><H><T><E><T><F><D><W><G><S><D><Y><Y><K><K><H><G><V><M><M><P><A><D><G><L><D><K><L><K><K><F><D><A><I><F><F><G><A><V><G><A><P><D><V><P><D><H><I><T><L><W><G><L><R><L><P><I><C><Q><G><F><D><Q><Y><A><N><V><R><P><T...
Has multiple catalytic activities. Apart from catalyzing the oxidation of (+)-tartrate to oxaloglycolate, also converts meso-tartrate to D-glycerate and catalyzes the oxidative decarboxylation of D-malate to pyruvate.<BOP>
O34295
B0SEH8
DAPAT_LEPBA
LL-diaminopimelate aminotransferase
Leptospira
<M><T><Q><I><N><E><N><Y><L><K><L><K><A><G><Y><L><F><P><E><I><G><R><R><V><K><A><Y><S><D><A><N><Q><N><A><K><I><I><R><L><G><I><G><D><V><T><L><P><L><A><P><T><I><V><N><A><M><V><D><A><A><K><E><M><G><S><A><G><G><F><H><G><Y><G><P><E><Q><G><Y><S><F><L><I><Q><K><I><I><A><H><D><Y><T><A><R><G><V><Q><I><A><E><D><E><V><F><V><S><D><G...
Involved in the synthesis of meso-diaminopimelate (m-DAP or DL-DAP), required for both lysine and peptidoglycan biosynthesis. Catalyzes the direct conversion of tetrahydrodipicolinate to LL-diaminopimelate.<BOP>
B0SEH8
B2UL21
RL25_AKKM8
General stress protein CTC
Akkermansia
<M><A><T><S><H><S><L><K><A><E><T><R><A><C><G><S><G><N><L><K><Q><L><R><S><Q><G><L><V><P><G><V><V><Y><G><P><G><F><D><N><V><N><I><Q><V><D><A><R><E><F><A><R><M><L><A><S><A><V><S><E><H><I><L><V><A><L><D><I><N><G><K><I><V><K><V><L><L><K><E><V><Q><H><N><P><I><T><N><A><C><L><H><V><D><F><Q><A><V><T><D><T><T><V><I><H><S><I><V><P...
This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance.<BOP>
B2UL21
Q3AMT7
RS10_SYNSC
30S ribosomal protein S10
unclassified Synechococcus
<M><S><T><A><I><A><Q><Q><K><I><R><I><R><L><K><A><F><D><R><R><M><L><D><L><S><C><E><K><I><I><E><T><A><D><N><T><A><A><T><A><I><G><P><I><P><L><P><T><K><R><K><I><Y><C><V><L><R><S><P><H><V><D><K><D><S><R><E><H><F><E><T><R><T><H><R><R><I><I><D><I><Y><S><P><S><A><K><T><I><D><A><L><M><K><L><D><L><P><S><G><V><D><I><E><V><K><L>
Involved in the binding of tRNA to the ribosomes.<BOP>
Q3AMT7
A1W0P5
DNAJ_CAMJJ
Chaperone protein DnaJ
Campylobacter
<M><E><I><S><Y><Y><E><L><L><E><I><T><Q><N><A><D><K><E><T><I><K><K><A><Y><R><K><M><A><L><K><Y><H><P><D><R><N><Q><G><D><K><E><A><E><D><K><F><K><L><V><N><E><A><Y><E><V><L><S><N><D><E><K><R><A><I><Y><D><R><Y><G><K><D><A><L><K><G><G><G><F><G><S><N><S><S><G><F><G><G><F><E><D><L><G><D><I><F><S><S><F><F><G><E><G><F><G><S><S><S...
Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bou...
A1W0P5
Q0IHM1
NLS1_XENTR
Major facilitator superfamily domain-containing protein 2A
Silurana
<M><E><K><E><S><E><N><A><S><C><A><G><L><L><G><Q><K><N><E><P><G><S><P><T><Q><S><R><S><G><K><H><K><L><S><V><C><S><K><I><C><F><A><I><G><G><A><P><Y><Q><I><T><G><C><A><L><G><F><F><L><Q><I><F><L><L><D><I><A><Q><V><P><P><F><Y><A><S><I><I><L><F><S><G><R><V><W><D><A><I><T><D><P><L><V><G><F><F><V><S><K><S><S><W><T><R><L><G><R><L...
Sodium-dependent lysophosphatidylcholine (LPC) symporter, which plays an essential role for blood-brain barrier formation and function. Specifically expressed in endothelium of the blood-brain barrier of micro-vessels and transports LPC into the brain. Transport of LPC is essential because it constitutes the major mech...
Q0IHM1
A1R8T8
RL16_PAEAT
50S ribosomal protein L16
Paenarthrobacter
<M><L><I><P><R><R><V><K><H><R><K><Q><H><H><P><G><R><S><G><A><A><T><G><G><T><K><V><S><F><G><E><Y><G><I><Q><A><L><S><P><A><Y><V><T><N><R><Q><I><E><S><A><R><I><A><M><T><R><H><I><K><R><G><G><K><V><W><I><N><I><Y><P><D><R><P><L><T><K><K><P><A><E><T><R><M><G><S><G><K><G><S><P><E><W><W><V><A><N><V><K><P><G><R><V><L><F><E><L><S...
Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.<BOP>
A1R8T8
Q3B6G3
EFTU_CHLL3
Elongation factor Tu
Pelodictyon
<M><A><K><E><S><Y><K><R><D><K><P><H><V><N><I><G><T><I><G><H><V><D><H><G><K><T><T><L><T><A><A><I><T><S><V><L><S><K><K><G><F><A><E><S><R><A><F><G><D><I><D><K><A><P><E><E><R><E><R><G><I><T><I><S><T><A><H><V><E><Y><Q><T><E><K><R><H><Y><A><H><I><D><C><P><G><H><A><D><Y><I><K><N><M><I><T><G><A><A><Q><M><D><G><A><I><L><V><V><A...
This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.<BOP>
Q3B6G3
B3PPU4
RECA_RHIE6
Recombinase A
Rhizobium
<M><S><Q><N><S><L><R><L><V><E><D><K><S><V><D><K><S><K><A><L><E><A><A><L><S><Q><I><E><R><S><F><G><K><G><S><I><M><K><L><G><S><N><E><N><V><I><E><I><E><T><I><S><T><G><S><L><G><L><D><I><A><L><G><V><G><G><L><P><K><G><R><I><I><E><I><Y><G><P><E><S><S><G><K><T><T><L><A><L><Q><T><I><A><E><S><Q><K><K><G><G><I><C><A><F><V><D><A><E...
Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage.<BOP>
B3PPU4
Q8N5M9
JAGN1_HUMAN
Protein jagunal homolog 1
Homo
<M><A><S><R><A><G><P><R><A><A><G><T><D><G><S><D><F><Q><H><R><E><R><V><A><M><H><Y><Q><M><S><V><T><L><K><Y><E><I><K><K><L><I><Y><V><H><L><V><I><W><L><L><L><V><A><K><M><S><V><G><H><L><R><L><L><S><H><D><Q><V><A><M><P><Y><Q><W><E><Y><P><Y><L><L><S><I><L><P><S><L><L><G><L><L><S><F><P><R><N><N><I><S><Y><L><V><L><S><M><I><S><M...
Endoplasmic reticulum transmembrane protein involved in vesicle-mediated transport, which is required for neutrophil function. Required for vesicle-mediated transport; it is however unclear whether it is involved in early secretory pathway or intracellular protein transport. Acts as a regulator of neutrophil function, ...
Q8N5M9
Q17Z49
PYRE_HELAH
Orotate phosphoribosyltransferase
Helicobacter
<M><D><V><K><A><C><Y><Q><N><A><K><A><L><L><E><G><H><F><L><L><S><S><G><F><H><S><N><Y><Y><L><Q><S><A><K><V><L><E><N><P><K><L><A><E><Q><L><A><L><E><L><A><K><Q><I><Q><N><A><R><L><N><I><E><C><V><C><S><P><A><I><G><G><I><L><A><G><Y><E><L><A><R><A><L><G><V><R><F><I><F><T><E><R><V><N><G><V><M><A><L><R><R><G><F><E><V><K><P><N><E...
Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).<BOP>
Q17Z49
P0A2B8
RMUC_SALTI
DNA recombination protein RmuC
Salmonella
<M><D><I><T><L><M><I><S><A><V><V><A><L><A><A><G><A><V><I><G><W><L><A><T><K><A><H><A><D><Q><I><R><A><D><L><I><E><E><R><R><E><L><D><I><E><L><S><A><A><R><Q><Q><L><A><Q><E><A><H><W><R><S><E><C><E><L><L><N><N><E><L><R><S><L><H><S><I><N><T><S><L><E><A><D><L><R><E><V><T><T><R><L><E><A><T><Q><Q><H><A><E><D><K><I><R><Q><M><I><N...
Involved in DNA recombination.<BOP>
P0A2B8
B6V866
MCPB_TRITO
Carboxypeptidase MCPB
Trichophyton
<M><V><A><Y><R><F><L><T><L><I><S><L><G><L><G><S><H><C><A><S><A><L><Q><Y><G><Y><N><Q><V><S><T><H><K><D><S><A><V><V><A><G><A><F><P><A><I><N><G><T><H><L><Q><S><P><A><F><T><S><P><G><T><V><P><R><G><F><S><D><G><T><S><G><P><T><R><D><E><T><M><E><G><F><M><R><R><L><A><R><S><N><S><W><M><T><Y><H><K><A><D><F><K><S><E><E><G><R><K><F...
Extracellular metalloprotease that contributes to pathogenicity.<BOP>
B6V866
Q1LNF7
EFTS_CUPMC
Elongation factor Ts
Cupriavidus
<M><A><A><I><T><A><S><M><V><A><E><L><R><A><K><T><D><A><P><M><M><E><C><K><K><A><L><T><E><A><D><G><D><L><G><K><A><E><E><L><L><R><V><K><L><G><N><K><A><S><K><A><A><S><R><V><T><A><E><G><I><V><V><S><Y><I><D><G><T><T><G><A><L><V><E><L><N><C><E><T><D><F><V><S><K><N><D><D><F><L><G><F><G><A><K><V><A><E><L><V><A><K><Q><N><P><A><D...
Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome.<BOP>
Q1LNF7
B0SXC3
SYY_CAUSK
Tyrosyl-tRNA synthetase
unclassified Caulobacter
<M><S><A><A><A><S><F><K><S><E><F><L><Q><T><L><Q><A><R><G><Y><I><H><Q><I><T><H><P><D><E><L><D><A><A><A><A><G><G><I><V><T><A><Y><I><G><F><D><A><T><A><P><S><L><H><V><G><S><L><I><Q><I><M><M><L><R><R><L><Q><Q><A><G><H><K><P><I><V><L><M><G><G><G><T><T><K><V><G><D><P><T><G><K><D><E><S><R><K><L><L><S><D><A><D><I><A><A><N><I><A...
Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).<BOP>
B0SXC3
A1U1Q6
MASZ_MARN8
Malate synthase G
Marinobacter
<M><T><E><R><V><Q><V><G><G><I><Q><I><A><K><N><L><Y><D><F><V><N><N><E><A><I><P><G><T><G><I><E><A><D><K><F><W><A><E><F><D><K><I><V><N><E><L><A><P><R><N><R><E><L><L><L><K><R><D><E><I><Q><E><K><M><D><T><W><N><R><E><H><K><G><Q><K><L><D><M><A><E><Y><K><A><F><L><K><D><I><G><Y><L><V><D><E><P><A><D><F><K><I><S><T><S><N><V><D><P...
Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA.<BOP>
A1U1Q6
A0E3W6
NNRE_PARTE
NAD(P)HX epimerase
Paramecium
<M><Q><Q><L><N><K><I><S><Y><L><N><Q><I><Q><S><Q><Q><F><D><V><E><L><M><S><E><E><V><G><F><T><L><D><Q><L><M><E><L><A><G><Q><S><I><A><N><T><V><V><Q><L><N><K><E><G><K><S><Y><N><K><I><L><V><L><C><G><P><G><N><N><G><G><D><G><I><V><S><A><R><H><L><K><Q><F><G><L><Q><P><E><I><A><L><F><R><E><V><K><N><P><F><F><N><R><L><L><N><Q><C><K...
Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX.<BOP>
A0E3W6
Q58141
ISF1_METJA
MCJ-1
Methanocaldococcus
<M><K><V><F><G><I><S><G><S><P><R><L><Q><G><T><H><F><A><V><N><Y><A><L><N><Y><L><K><E><K><G><A><E><V><R><Y><F><S><V><S><R><K><K><I><N><F><C><L><H><C><D><Y><C><I><K><K><K><E><G><C><I><H><K><D><D><M><E><E><V><Y><E><N><L><I><W><A><D><G><V><I><I><G><T><P><V><Y><Q><G><N><V><T><G><Q><L><K><T><L><M><D><R><C><R><A><I><L><A><K><N...
Redox-active protein probably involved in electron transport.<BOP>
Q58141
Q7WFN9
SYP_BORBR
Prolyl-tRNA synthetase
Bordetella
<M><R><A><S><K><Y><H><L><N><T><L><K><E><A><P><A><E><A><E><I><A><S><H><Q><L><M><T><R><A><G><M><I><R><K><L><A><G><G><I><Y><T><Y><M><P><L><G><L><K><V><I><R><K><I><E><G><I><V><R><E><E><M><N><A><A><G><A><I><E><L><L><M><P><V><V><Q><P><A><E><L><W><M><E><S><G><R><W><E><Q><Y><G><A><E><L><L><R><I><K><D><R><H><Q><R><D><F><V><L><Q...
Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two addit...
Q7WFN9
Q12084
DAS2_YEAST
Regulator of rDNA transcription 3
Saccharomyces
<M><D><R><K><A><V><E><E><K><R><I><V><I><S><I><G><G><G><H><A><T><G><V><G><A><I><A><L><D><L><Q><N><T><F><K><S><L><Y><N><S><I><N><I><R><V><I><N><L><D><N><M><I><E><G><N><I><K><S><Y><N><N><N><D><Y><D><F><D><N><I><L><N><L><V><Y><E><K><H><A><V><T><S><Q><N><D><M><I><Q><H><D><Y><E><D><P><I><D><L><I><I><V><C><G><C><Y><A><L><Y><D...
Putative uridine kinase identified in a screen for mutants with increased levels of rDNA transcription.<BOP>
Q12084
Q8WVK2
SNR27_HUMAN
U4/U6.U5 tri-snRNP-associated protein 3
Homo
<M><G><R><S><R><S><R><S><P><R><R><E><R><R><R><S><R><S><T><S><R><E><R><E><R><R><R><R><E><R><S><R><S><R><E><R><D><R><R><R><S><R><S><R><S><P><H><R><R><R><S><R><S><P><R><R><H><R><S><T><S><P><S><P><S><R><L><K><E><R><R><D><E><E><K><K><E><T><K><E><T><K><S><K><E><R><Q><I><T><E><E><D><L><E><G><K><T><E><E><E><I><E><M><M><K><L><M...
May play a role in mRNA splicing.<BOP>
Q8WVK2
Q1DCA3
GATA_MYXXD
Glutamyl-tRNA(Gln) amidotransferase subunit A
Myxococcus
<M><Q><L><T><D><L><T><M><L><E><L><A><A><K><L><A><A><G><E><A><S><S><E><E><A><T><R><A><S><L><A><R><I><Q><Q><V><D><P><K><V><R><A><F><L><R><V><D><E><A><G><A><L><A><A><A><R><A><S><D><A><R><R><K><S><G><S><P><A><S><A><L><D><G><V><P><L><G><L><K><D><I><F><L><T><E><G><V><E><T><T><A><G><S><R><I><L><E><G><F><V><P><P><Y><D><A><T><V...
Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).<BOP>
Q1DCA3
B0BN28
SKA1_RAT
Spindle and kinetochore-associated protein 1
Rattus
<M><A><S><D><L><E><Q><L><C><S><Y><V><N><E><K><I><E><N><I><K><K><I><L><S><L><R><K><L><G><Q><D><P><T><L><K><T><T><L><S><K><I><G><D><E><I><I><T><V><N><E><L><L><N><Q><F><E><L><E><I><Q><Y><Q><E><Q><T><N><S><S><L><K><E><L><C><K><S><L><E><E><E><F><K><D><V><E><H><L><K><E><H><I><P><S><H><L><P><Q><V><T><V><T><Q><S><S><T><H><K><P...
Component of the SKA1 complex, a microtubule-binding subcomplex of the outer kinetochore that is essential for proper chromosome segregation. Required for timely anaphase onset during mitosis, when chromosomes undergo bipolar attachment on spindle microtubules leading to silencing of the spindle checkpoint. The SKA1 co...
B0BN28
Q39FQ7
RLMN_BURL3
tRNA m2A37 methyltransferase
Burkholderia cepacia complex
<M><T><S><E><T><T><V><N><L><L><D><F><D><A><E><G><L><V><A><Y><C><G><S><L><G><E><K><P><F><R><A><K><Q><L><Q><R><W><I><H><Q><Y><N><A><G><D><F><D><G><M><T><D><L><A><K><S><L><R><E><K><L><K><G><R><A><S><I><G><M><P><E><I><A><S><D><H><V><S><T><D><G><T><R><K><W><L><I><D><V><G><N><G><N><A><V><E><T><V><F><I><P><E><E><T><R><G><T><L...
Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs. m2A2503 modification seems to play a crucial role in the proofreading step occurring at the peptidyl transferase center and thus would serve to optimize ribosomal fidelity.<BOP>
Q39FQ7
Q11T75
ACPS_CYTH3
4'-phosphopantetheinyl transferase AcpS
Cytophaga
<M><I><Q><G><I><G><V><D><I><V><D><I><A><R><M><Q><Q><R><I><D><A><A><S><G><F><R><E><L><V><F><S><P><A><E><I><T><Y><C><E><S><K><A><N><K><Y><E><S><Y><A><A><R><F><A><A><K><E><A><F><L><K><A><V><G><I><G><I><D><F><S><I><D><L><N><Q><I><E><I><T><N><N><K><A><G><K><P><Y><F><V><Y><T><K><Q><V><E><A><L><L><L><T><H><I><G><F><V><P><D><A...
Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein.<BOP>
Q11T75
Q8BUK6
HOOK3_MOUSE
Protein Hook homolog 3
Mus
<M><F><N><V><E><S><V><E><R><V><E><L><C><E><S><L><L><T><W><I><Q><T><F><N><V><D><A><P><C><Q><T><A><E><D><L><T><N><G><V><V><M><S><Q><V><L><Q><K><I><D><P><V><Y><F><D><D><N><W><L><N><R><I><K><T><E><V><G><D><N><W><R><L><K><I><S><N><L><K><K><I><L><K><G><I><L><D><Y><N><H><E><I><L><G><Q><Q><I><N><D><F><T><L><P><D><V><N><L><I><G...
(Microbial infection) Serves as a target for the spiC protein from Salmonella typhimurium, which inactivates it, leading to a strong alteration in cellular trafficking.<BOP>
Q8BUK6
Q0TV32
SELO_CLOP1
Protein adenylyltransferase SelO
Clostridium
<M><D><N><K><N><F><Q><S><K><T><G><F><N><L><E><N><T><Y><L><T><L><P><N><I><F><F><S><E><Q><N><P><K><G><S><K><N><P><K><L><I><K><F><N><T><S><L><A><E><E><L><G><L><N><E><E><V><L><N><S><D><F><G><L><N><I><F><A><G><N><E><T><F><P><G><I><V><P><I><A><Q><A><Y><A><G><H><Q><F><G><H><F><T><M><L><G><D><G><R><A><L><L><L><G><E><H><V><T><K...
Catalyzes the transfer of adenosine 5'-monophosphate (AMP) to Ser, Thr or Tyr residues of target proteins (AMPylation).<BOP>
Q0TV32
A4SHL4
CYSG1_AERS4
Sirohydrochlorin ferrochelatase 1
Aeromonas
<M><D><Y><L><P><I><F><C><R><L><D><N><K><P><V><L><L><V><G><G><G><E><V><A><E><R><K><A><R><L><L><L><D><A><G><A><R><L><T><V><V><S><P><A><L><D><P><E><L><A><A><L><A><T><S><G><T><I><D><W><L><A><A><E><F><E><P><A><H><L><T><G><K><W><L><V><V><A><A><T><D><R><R><E><V><N><A><L><V><Y><Q><S><A><N><Q><A><G><I><F><A><N><V><V><D><D><P><K...
Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yie...
A4SHL4
Q5WLW2
RSMA_ALKCK
S-adenosylmethionine-6-N', N'-adenosyl(rRNA) dimethyltransferase
Alkalihalobacillus
<M><N><L><N><K><D><I><A><T><P><A><R><T><N><A><I><L><K><K><H><G><F><T><L><K><K><S><L><G><Q><N><F><L><I><D><L><N><I><L><A><K><I><V><E><A><S><G><F><D><E><Q><D><G><I><V><E><I><G><P><G><I><G><A><L><T><E><Q><L><A><K><K><A><D><K><V><V><A><F><E><I><D><G><R><L><I><P><V><L><E><D><T><L><S><A><Y><P><N><V><K><I><I><H><S><D><V><L><K...
Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits.<BOP>
Q5WLW2
Q0RDP3
RIMM_FRAAA
Ribosome maturation factor RimM
Frankia
<M><T><E><P><I><V><V><G><R><I><G><R><P><H><G><V><R><G><D><V><T><I><E><V><R><T><D><L><P><Q><R><R><F><A><L><G><A><V><L><G><R><E><G><G><G><A><P><L><T><V><A><E><A><R><W><H><S><G><R><L><L><L><R><F><Q><G><V><E><D><R><G><A><A><E><A><L><R><D><V><L><L><T><I><D><S><A><E><A><G><P><P><V><D><D><D><E><D><A><E><G><E><G><G><D><I><W><W...
An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosoma...
Q0RDP3
C4K8P2
RIBB_HAMD5
3,4-dihydroxy-2-butanone 4-phosphate synthase
Candidatus Hamiltonella
<M><N><Q><I><C><L><E><Y><F><G><N><S><V><A><R><V><K><K><A><L><E><N><L><K><N><G><H><G><V><M><V><L><D><D><E><N><R><E><N><E><G><D><F><V><F><A><A><E><T><M><T><V><E><Q><M><A><L><T><I><R><H><G><S><G><I><V><C><L><C><L><T><E><E><R><C><Q><Q><L><E><L><P><M><M><V><E><K><N><S><S><T><F><Q><T><P><F><T><V><S><I><E><A><A><K><G><V><T><T...
Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate.<BOP>
C4K8P2
A4F7R9
RS14_SACEN
30S ribosomal protein S14
Saccharopolyspora
<M><A><K><K><S><K><I><A><R><D><A><Q><R><R><A><V><V><A><R><Y><A><Q><R><R><A><E><L><K><R><I><I><A><A><P><G><S><S><P><E><E><R><A><A><A><Q><Q><E><L><R><R><Q><P><R><D><A><S><A><T><R><L><R><N><R><D><A><V><D><G><R><P><R><G><Y><F><R><K><F><G><L><S><R><V><R><L><R><Q><L><A><H><S><G><E><L><P><G><V><T><K><S><S><W>
Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.<BOP>
A4F7R9
Q65EM1
LUTC_BACLD
Lactate utilization protein C
Bacillus
<M><T><N><G><T><I><H><N><K><D><G><F><L><N><R><I><A><E><R><L><G><R><N><R><R><S><A><G><V><T><V><P><D><Y><I><H><Q><P><Q><H><R><V><Y><Q><G><Y><T><Q><D><E><L><V><G><V><L><K><D><H><C><R><K><I><H><T><E><L><I><E><T><D><V><I><G><L><H><D><A><L><Y><E><Q><A><A><R><F><G><G><G><P><V><M><I><P><K><D><D><R><F><K><E><Y><G><L><S><G><L><L...
Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source.<BOP>
Q65EM1
Q9WYU3
PDXT_THEMA
Pyridoxal 5'-phosphate synthase glutaminase subunit
Thermotoga
<M><K><I><G><V><L><G><V><Q><G><D><V><R><E><H><V><E><A><L><H><K><L><G><V><E><T><L><I><V><K><L><P><E><Q><L><D><M><V><D><G><L><I><L><P><G><G><E><S><T><T><M><I><R><I><L><K><E><M><D><M><D><E><K><L><V><E><R><I><N><N><G><L><P><V><F><A><T><C><A><G><V><I><L><L><A><K><R><I><K><N><Y><S><Q><E><K><L><G><V><L><D><I><T><V><E><R><N><A...
Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS.<BOP>
Q9WYU3
B7UIC1
LEUD_ECO27
Isopropylmalate isomerase
Escherichia
<M><A><E><K><F><I><K><H><T><G><L><V><V><P><L><D><A><A><N><V><D><T><D><A><I><I><P><K><Q><F><L><Q><K><V><T><R><T><G><F><G><A><H><L><F><N><D><W><R><F><L><D><E><K><G><Q><Q><P><N><P><D><F><V><L><N><F><P><Q><Y><Q><G><A><S><I><L><L><A><R><E><N><F><G><C><G><S><S><R><E><H><A><P><W><A><L><T><D><Y><G><F><K><V><V><I><A><P><S><F><A...
Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.<BOP>
B7UIC1
Q2G8K8
PYRH_NOVAD
Uridine monophosphate kinase
Novosphingobium
<M><S><L><P><S><C><V><P><G><Y><R><R><I><L><L><K><L><S><G><E><V><L><M><G><E><Q><Q><F><G><I><D><T><D><Y><V><A><R><V><A><Q><E><V><K><D><A><R><D><S><G><L><E><I><C><L><V><I><G><G><G><N><I><F><R><G><M><A><G><A><A><K><G><M><D><R><A><Q><A><D><Y><M><G><M><L><A><T><V><M><N><A><L><A><M><Q><S><A><L><E><Q><L><G><V><P><T><R><V><Q><S...
Catalyzes the reversible phosphorylation of UMP to UDP.<BOP>
Q2G8K8
A0RKF7
LIPA_BACAH
Sulfur insertion protein LipA
Bacillus cereus group
<M><T><K><Q><T><E><Y><K><R><K><P><E><W><L><K><I><K><L><N><T><N><E><N><Y><T><G><L><K><K><M><M><R><S><K><N><L><H><T><V><C><E><E><A><K><C><P><N><I><H><E><C><W><A><V><R><K><T><A><T><F><M><I><L><G><A><V><C><T><R><A><C><R><F><C><A><V><K><T><G><L><P><T><E><L><D><L><Q><E><P><E><R><V><A><D><S><V><V><Q><M><G><L><K><H><V><V><I><T...
Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.<BOP>
A0RKF7
Q7YC75
CYB_CHRGO
Ubiquinol-cytochrome-c reductase complex cytochrome b subunit
Chrotomys
<M><T><N><I><R><K><T><H><P><L><I><K><I><I><N><H><S><F><I><D><L><P><A><P><S><N><I><S><S><W><W><N><F><G><S><L><L><G><L><C><L><M><I><Q><I><I><T><G><L><F><L><A><M><H><Y><T><S><D><T><T><T><A><F><S><S><V><A><H><I><C><R><D><V><N><Y><G><W><L><I><R><Y><M><H><A><N><G><A><S><M><F><F><I><C><L><F><L><H><V><G><R><G><M><Y><Y><G><S><Y...
Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain. The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c. Contributes to the generation of a proton gradient across the mitochondrial membrane that is...
Q7YC75
Q2A5L1
CYOE_FRATH
Heme O synthase
Francisella
<M><Y><F><K><R><Y><L><Q><L><A><K><P><G><I><I><F><G><N><L><I><T><L><T><G><G><F><L><L><A><T><H><R><E><I><G><F><E><Y><L><P><L><F><V><Y><V><M><I><G><V><A><L><M><I><A><A><G><C><V><F><N><N><I><Y><D><Q><D><I><D><S><S><M><T><R><T><Q><N><R><P><L><V><T><G><D><I><S><V><I><Q><A><T><I><Y><G><T><I><L><L><I><L><S><C><L><V><L><Y><Y><L...
Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group.<BOP>
Q2A5L1
O80809
CLV2_ARATH
Receptor-like protein 10
Arabidopsis
<M><I><K><I><A><D><F><T><L><F><F><F><I><F><V><F><S><P><S><L><P><L><A><Q><S><Q><L><P><D><L><D><P><Q><D><K><A><S><L><L><I><F><R><V><S><I><H><D><L><N><R><S><L><S><T><W><Y><G><S><S><C><S><N><W><T><G><L><A><C><Q><N><P><T><G><K><V><L><S><L><T><L><S><G><L><N><L><S><S><Q><I><H><P><S><L><C><K><L><S><S><L><Q><S><L><D><L><S><H><N...
Involved in the perception of CLV3 and CLV3-like (CLE) peptides, that act as extracellular signals regulating meristems maintenance. Required for the sensing of the root CLE peptides (e.g. CLE8, CLE9/CLE10, CLE11, CLE13, CLE14, CLE16, CLE17, CLE18, CLE20, CLE21, CLE25, CLE26, CLE40, CLE41/CLE44 and CLE45), which involv...
O80809
C0ZYQ1
NRDR_RHOE4
Transcriptional repressor NrdR
Rhodococcus erythropolis group
<M><H><C><P><F><C><R><H><P><D><S><R><V><V><D><S><R><E><A><D><E><G><Q><A><I><R><R><R><R><S><C><P><E><C><G><R><R><F><T><T><V><E><T><A><V><L><S><V><V><K><R><S><G><V><T><E><P><F><S><R><E><K><V><V><K><G><V><R><R><A><C><Q><G><R><Q><V><D><N><D><S><L><N><L><L><A><Q><Q><V><E><D><A><V><R><A><S><G><S><A><E><I><P><S><N><E><V><G><L...
Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes.<BOP>
C0ZYQ1
Q9F5X1
MNMG_PSEU2
Glucose-inhibited division protein A
Pseudomonas syringae
<M><V><D><F><P><S><R><F><E><V><I><V><I><G><G><G><H><A><G><T><E><A><A><L><A><S><A><R><M><G><V><K><T><L><L><L><T><H><N><V><E><T><L><G><Q><M><S><C><N><P><A><I><G><G><I><G><K><S><H><L><V><K><E><I><D><A><L><G><G><A><M><A><M><A><T><D><K><G><G><I><Q><F><R><V><L><N><S><R><K><G><P><A><V><R><A><T><R><A><Q><A><D><R><V><L><Y><K><A...
NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.<BOP>
Q9F5X1
C6E229
CMOB_GEOSM
tRNA U34 carboxymethyltransferase
unclassified Geobacter
<M><S><N><Y><D><A><L><Y><S><Q><L><V><A><M><G><Q><E><R><W><A><E><Q><L><Q><A><T><L><P><D><K><L><A><L><E><S><T><A><K><M><A><G><W><Q><S><A><M><Q><S><L><P><E><I><R><P><S><R><I><E><L><K><E><N><V><T><I><G><T><S><D><D><L><G><D><I><N><R><E><E><L><I><A><L><L><Q><A><F><H><P><W><R><K><G><P><Y><N><F><F><G><I><E><I><D><T><E><W><R><S...
Catalyzes carboxymethyl transfer from carboxy-S-adenosyl-L-methionine (Cx-SAM) to 5-hydroxyuridine (ho5U) to form 5-carboxymethoxyuridine (cmo5U) at position 34 in tRNAs.<BOP>
C6E229
B3PK36
RS10_CELJU
30S ribosomal protein S10
Cellvibrio
<M><Q><N><Q><R><I><R><I><R><L><K><A><F><D><H><K><L><I><D><A><S><T><Q><E><I><V><E><T><A><K><R><T><G><A><Q><V><R><G><P><I><P><L><P><T><R><K><E><R><F><T><V><L><I><S><P><H><V><N><K><D><A><R><D><Q><Y><E><I><R><T><H><K><R><L><L><D><I><V><E><P><T><E><K><T><V><D><A><L><M><K><L><D><L><A><A><G><V><E><V><Q><I><S><L><G>
Involved in the binding of tRNA to the ribosomes.<BOP>
B3PK36
Q962S7
RL37_SPOFR
60S ribosomal protein L37
Spodoptera
<M><T><K><G><T><S><S><F><G><K><R><R><N><K><T><H><T><L><C><R><R><C><G><R><S><S><Y><H><I><Q><K><S><K><C><A><Q><C><G><Y><P><A><A><K><L><R><S><Y><H><W><S><V><K><A><K><R><R><K><T><T><G><T><G><R><M><R><H><L><K><I><V><R><R><R><F><R><N><G><F><K><E><G><K><P><T><P><K><K><A><V><A><S><S>
Binds to the 23S rRNA.<BOP>
Q962S7
Q9LXJ1
BIC1_ARATH
BLUE-LIGHT INHIBITOR OF CRYPTOCHROMES 1
Arabidopsis
<M><M><N><I><D><D><T><T><S><P><M><A><H><P><I><G><P><S><Q><P><P><S><D><Q><T><K><Q><D><P><P><S><L><P><Q><E><A><A><S><S><V><S><A><D><K><K><D><L><A><L><L><E><E><K><P><K><Q><S><Q><E><E><D><R><V><D><T><G><R><E><R><L><K><K><H><R><R><E><I><A><G><R><V><W><I><P><E><I><W><G><Q><E><E><L><L><K><D><W><I><D><C><S><T><F><D><T><C><L><V...
Regulates the blue-light dependent dimerization of CRY2 and formation of photobodies. Interacts with photoexited CRY2 to inhibit its activity. Inhibits CRY phosphorylation.<BOP>
Q9LXJ1
P46491
CRCB_HAEIN
Putative fluoride ion transporter CrcB
Haemophilus
<M><Q><A><L><L><F><I><S><Y><G><A><I><L><G><A><S><L><R><W><A><I><G><L><L><F><N><P><L><F><S><S><F><A><F><G><T><L><I><A><N><L><F><G><C><L><I><I><G><V><L><L><G><L><F><W><Q><F><P><Q><I><S><A><E><W><R><L><F><L><I><T><G><F><L><G><S><L><T><T><F><S><S><F><S><S><E><V><V><E><L><F><F><N><D><K><W><L><N><G><F><C><V><L><M><M><H><L><F...
Important for reducing fluoride concentration in the cell, thus reducing its toxicity.<BOP>
P46491
B8D9Q1
TIG_BUCA5
PPIase
Buchnera
<M><N><F><F><M><E><K><N><K><D><A><G><H><R><V><T><I><K><I><P><K><T><T><V><N><N><S><L><L><Q><E><F><I><K><I><R><K><T><T><K><I><N><G><F><R><K><G><K><T><P><I><R><V><I><Q><E><K><Y><G><S><A><I><Y><Y><D><I><F><K><K><L><M><Q><K><F><F><Y><E><F><I><K><T><E><K><I><K><I><I><G><S><P><K><F><Y><I><H><Q><D><E><D><K><K><K><E><Y><F><E><Y...
Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase.<BOP>
B8D9Q1
Q8YC99
LIVB6_BRUME
Leu/Ile/Val-binding protein homolog 6
Brucella
<M><K><K><I><A><L><T><A><L><A><V><F><S><L><A><A><S><A><A><Y><A><D><V><V><K><V><G><V><I><G><P><F><S><G><P><F><A><L><Q><G><K><N><F><K><A><G><I><D><A><Y><M><A><E><H><G><N><K><V><G><D><D><T><V><E><V><V><Y><R><D><V><P><Q><A><D><P><A><Q><S><K><A><L><A><Q><E><L><V><V><K><E><G><V><Q><Y><L><A><G><F><Y><F><T><P><D><A><M><A><V><T...
Component of an amino-acid transport system.<BOP>
Q8YC99
A0RXV1
PSB2_CENSY
Proteasome core protein PsmB 2
Cenarchaeum
<M><S><N><N><V><E><E><K><I><L><H><G><T><T><T><V><G><I><K><A><T><D><G><V><V><L><C><A><D><M><R><A><S><A><G><Y><F><I><A><N><N><N><T><M><K><I><Q><R><I><D><D><H><A><G><L><T><L><A><G><G><V><A><D><A><Q><N><I><V><D><V><L><R><Y><H><A><S><L><H><R><I><R><K><Q><G><P><I><P><I><K><S><L><A><R><L><T><S><L><I><F><H><Q><N><R><G><Y><P><F...
Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation.<BOP>
A0RXV1
P43631
KI2S2_HUMAN
p58 natural killer cell receptor clone CL-49
Homo
<M><S><L><M><V><V><S><M><A><C><V><G><F><F><L><L><Q><G><A><W><P><H><E><G><V><H><R><K><P><S><L><L><A><H><P><G><P><L><V><K><S><E><E><T><V><I><L><Q><C><W><S><D><V><R><F><E><H><F><L><L><H><R><E><G><K><Y><K><D><T><L><H><L><I><G><E><H><H><D><G><V><S><K><A><N><F><S><I><G><P><M><M><Q><D><L><A><G><T><Y><R><C><Y><G><S><V><T><H><S...
Receptor on natural killer (NK) cells for HLA-C alleles. Does not inhibit the activity of NK cells.<BOP>
P43631
Q92T28
MGSA_RHIME
Methylglyoxal synthase
Sinorhizobium
<M><A><D><R><K><C><L><A><L><I><A><H><D><Q><K><K><D><D><L><A><A><F><A><K><A><N><E><A><V><L><S><K><W><K><I><V><A><T><G><T><T><G><G><R><V><L><D><V><C><P><A><L><D><I><V><R><L><K><S><G><P><L><G><G><D><Q><Q><I><G><A><L><I><A><T><G><D><V><D><C><L><I><F><F><V><D><P><L><T><A><M><P><H><D><V><D><V><K><A><L><M><R><L><A><I><V><Y><D...
Catalyzes the formation of methylglyoxal from dihydroxyacetone phosphate.<BOP>
Q92T28
Q6MIR9
NUOI_BDEBA
NDH-1 subunit I
Bdellovibrio
<M><S><V><M><Q><N><N><S><E><K><S><K><W><F><L><P><G><I><L><G><G><L><A><T><T><M><K><H><L><L><K><N><L><F><N><Q><K><K><M><M><T><L><N><Y><P><E><E><K><Y><E><Y><S><P><R><F><K><G><N><H><V><L><T><V><K><K><D><G><S><L><R><C><T><A><C><M><L><C><A><T><N><C><P><A><E><C><I><K><I><T><A><A><E><H><N><D><P><T><V><E><K><F><P><I><S><Y><E><I...
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are t...
Q6MIR9
Q08048
HGF_MOUSE
Hepatocyte growth factor beta chain
Mus
<M><M><W><G><T><K><L><L><P><V><L><L><L><Q><H><V><L><L><H><L><L><L><L><H><V><A><I><P><Y><A><E><G><Q><K><K><R><R><N><T><L><H><E><F><K><K><S><A><K><T><T><L><T><K><E><D><P><L><L><K><I><K><T><K><K><V><N><S><A><D><E><C><A><N><R><C><I><R><N><R><G><F><T><F><T><C><K><A><F><V><F><D><K><S><R><K><R><C><Y><W><Y><P><F><N><S><M><S><S...
Potent mitogen for mature parenchymal hepatocyte cells, seems to be a hepatotrophic factor, and acts as a growth factor for a broad spectrum of tissues and cell types. Activating ligand for the receptor tyrosine kinase MET by binding to it and promoting its dimerization.<BOP>
Q08048
A9WT08
DCDB_RENSM
DCD-DUT
Renibacterium
<M><L><I><S><D><R><D><I><R><T><Q><I><D><S><G><R><I><V><L><D><P><F><E><P><S><M><V><Q><P><S><S><V><D><V><R><I><D><K><L><F><R><L><F><D><N><H><K><Y><A><H><I><D><P><A><E><E><Q><P><E><L><T><R><L><V><E><V><A><A><D><E><P><F><I><L><H><P><G><E><F><V><L><G><S><T><Y><E><A><V><T><L><P><D><D><V><A><A><R><L><E><G><K><S><S><L><G><R><L...
Bifunctional enzyme that catalyzes both the deamination of dCTP to dUTP and the hydrolysis of dUTP to dUMP without releasing the toxic dUTP intermediate.<BOP>
A9WT08
Q7YWU9
UBXN5_CAEEL
UBX domain-containing protein 5
Caenorhabditis
<M><P><T><N><N><H><V><Q><K><E><K><F><A><E><D><R><A><L><L><S><Q><Q><N><K><E><Y><A><E><S><L><A><K><D><I><A><K><K><E><E><K><D><K><I><R><F><E><A><E><Q><K><E><L><R><K><K><T><I><Q><D><Y><R><E><K><L><K><G><T><V><S><Q><G><P><L><R><L><L><V><R><Y><P><N><G><S><R><L><I><L><S><F><S><P><S><Q><P><M><T><S><L><F><D><A><I><I><L><N><P><A...
Probably acts as an adapter for ATPase cdc-48.1 and/or cdc-48.2, conferring substrate specificity. Unlike other UBX domain-containing protein does not bind 'Lys-48'-polyubiquitinated chain.<BOP>
Q7YWU9
Q8X5V6
DUSA_ECO57
tRNA-dihydrouridine synthase A
Escherichia
<M><H><G><N><S><E><M><Q><K><I><N><Q><T><S><A><M><P><E><K><T><D><V><H><W><S><G><R><F><S><V><A><P><M><L><D><W><T><D><R><H><C><R><Y><F><L><R><L><L><S><R><N><T><L><L><Y><T><E><M><V><T><T><G><A><I><I><H><G><K><G><D><Y><L><A><Y><S><E><E><E><H><P><V><A><L><Q><L><G><G><S><D><P><A><A><L><A><Q><C><A><K><L><A><E><A><R><G><Y><D><E...
Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines. Specifically modifies U20 and U20a in tRNAs.<BOP>
Q8X5V6