accession stringlengths 6 10 | name stringlengths 6 11 | Full Name stringlengths 1 147 ⌀ | taxon stringlengths 3 46 ⌀ | sequence stringlengths 48 8.26k | function stringlengths 11 5.52k | AlphaFoldDB stringlengths 6 10 |
|---|---|---|---|---|---|---|
P93471 | COP1_PEA | RING-type E3 ubiquitin transferase COP1 | Pisum | <M><E><E><H><S><V><G><P><L><V><P><A><V><V><K><P><E><P><S><K><N><F><S><T><D><T><T><A><A><G><T><F><L><L><V><P><T><M><S><D><L><D><K><D><F><L><C><P><I><C><M><Q><I><I><K><D><A><F><L><T><A><C><G><H><S><F><C><Y><M><C><I><I><T><H><L><R><N><K><S><D><C><P><C><C><G><H><Y><L><T><N><S><N><L><F><P><N><F><L><L><D><K><L><L><K><K><T><S... | E3 ubiquitin-protein ligase that acts as a repressor of photomorphogenesis and as an activator of etiolation in darkness. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. Represses photomorphogenesi... | P93471 |
C3MG28 | FLGH_SINFN | Basal body L-ring protein | Sinorhizobium | <M><R><M><Q><L><T><A><V><L><A><A><S><L><L><A><G><C><Q><N><Q><A><F><R><E><I><G><Q><A><P><S><M><S><P><I><G><S><G><L><Q><Y><T><Q><A><P><Q><L><A><A><Y><P><K><Q><P><H><Q><M><T><A><G><Y><S><L><W><N><D><Q><Q><A><A><L><F><K><D><A><R><A><I><N><V><G><D><I><L><T><V><D><I><Q><I><D><D><K><A><S><F><N><N><E><T><D><R><S><R><T><N><S><S... | Assembles around the rod to form the L-ring and probably protects the motor/basal body from shearing forces during rotation.<BOP> | C3MG28 |
O25655 | PYRD_HELPY | Dihydroorotate oxidase | Helicobacter | <M><L><Y><S><L><V><K><K><Y><L><F><S><L><D><A><E><D><A><H><E><K><V><C><K><I><L><R><M><L><S><S><S><P><F><L><C><N><L><I><D><S><Q><W><G><Y><Q><N><P><K><L><E><N><E><I><L><G><L><H><F><P><N><P><L><G><L><A><A><G><F><D><K><N><A><S><M><L><R><A><L><M><A><F><G><F><G><Y><L><E><A><G><T><L><T><N><E><A><Q><V><G><N><E><R><P><R><L><F><R... | Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor.<BOP> | O25655 |
O22056 | SIGB_ARATH | RNA polymerase sigma factor sigA | Arabidopsis | <M><S><S><C><L><L><P><Q><F><K><C><P><P><D><S><F><S><I><H><F><R><T><S><F><C><A><P><K><H><N><K><G><S><V><F><F><Q><P><Q><C><A><V><S><T><S><P><A><L><L><T><S><M><L><D><V><A><K><L><R><L><P><S><F><D><T><D><S><D><S><L><I><S><D><R><Q><W><T><Y><T><R><P><D><G><P><S><T><E><A><K><Y><L><E><A><L><A><S><E><T><L><L><T><S><D><E><A><V><V... | Required for the transition of plastids into chloroplasts by coordinating nuclear and chloroplastic genomes under light conditions. Sigma factors are initiation factors that promote the attachment of plastid-encoded RNA polymerase (PEP) to specific initiation sites and are then released. Promotes the biosynthesis of pl... | O22056 |
Q8JZU0 | NUD13_MOUSE | Nucleoside diphosphate-linked moiety X motif 13 | Mus | <M><S><L><Y><C><R><T><F><F><R><R><K><S><F><G><C><Y><R><L><L><S><T><Y><V><T><K><A><R><Y><L><F><E><L><K><E><D><E><E><A><C><R><K><A><Q><K><T><G><V><F><Y><L><F><H><D><L><D><P><L><L><Q><A><S><G><H><R><Y><L><V><P><R><L><S><R><A><E><L><E><G><L><L><G><K><F><G><Q><D><S><Q><R><I><E><D><S><V><L><V><G><C><S><E><Q><Q><E><A><W><F><A... | NAD(P)H pyrophosphatase that hydrolyzes NADH into NMNH and AMP, and NADPH into NMNH and 2',5'-ADP . Has a marked preference for the reduced pyridine nucleotides . Does not show activity toward NAD-capped RNAs; the NAD-cap is an atypical cap present at the 5'-end of some RNAs .<BOP> | Q8JZU0 |
Q6X9Z5 | RLA2_HORSE | 60S acidic ribosomal protein P2 | Equus | <M><R><Y><V><A><S><Y><L><L><A><A><L><G><G><N><T><S><P><S><A><K><D><I><K><K><I><L><D><S><V><G><I><E><A><D><D><D><R><L><D><K><V><I><S><E><L><N><G><K><N><I><E><D><V><I><A><Q><G><I><G><K><L><A><S><V><P><A><G><G><A><V><A><V><S><A><A><P><G><S><A><A><P><A><A><G><S><A><P><A><A><A><E><E><R><K><E><E><K><K><E><E><S><E><E><S><D><D... | Plays an important role in the elongation step of protein synthesis.<BOP> | Q6X9Z5 |
P68253 | 1433G_SHEEP | Protein kinase C inhibitor protein 1 | Ovis | <A><A><A><M><K><N><V><T><E><L><N><E><P><L><S><N><E><E><R><N><L><L><S><V><A><Y><K><N><V><V><G><A><R><R><S><S><W><R><V><I><S><S><I><E><Q><K><T><S><F><Y><L><K><M><K><G><D><Y><Y><R><Y><L><A><E><V><A><T><G><E><K><R><A><T><V><V><E><S><S><E><K><A><Y><S><E><A><H><E><I><S><K><E><H><M><Q><P><T><H><P><I><R><L><G><L><A><L><N><Y><S... | Adapter protein implicated in the regulation of a large spectrum of both general and specialized signaling pathways. Binds to a large number of partners, usually by recognition of a phosphoserine or phosphothreonine motif. Binding generally results in the modulation of the activity of the binding partner.<BOP> | P68253 |
Q2RJF1 | END4_MOOTA | Endonuclease IV | Moorella | <M><R><L><G><A><H><L><S><I><A><K><G><L><P><R><T><A><A><M><A><T><S><I><G><A><N><T><F><Q><Y><F><T><R><N><P><R><G><G><A><A><R><Q><I><P><G><K><E><I><Q><A><W><R><E><A><R><R><R><A><D><L><Y><P><I><A><G><H><L><P><Y><T><V><N><L><G><A><A><A><E><R><Q><Q><E><F><T><R><M><V><L><H><D><D><T><L><R><V><A><A><I><D><G><E><Y><L><I><S><H><P... | Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic (AP) sites, generating a 3'-hydroxyl group and a 5'-terminal sugar phosphate.<BOP> | Q2RJF1 |
A6LD62 | RNY_PARD8 | Ribonuclease Y | Parabacteroides | <M><V><G><M><Y><I><I><I><P><I><V><T><F><I><I><G><G><L><L><A><W><L><G><M><R><F><L><L><K><S><K><Y><D><S><V><L><Q><E><A><E><K><E><A><E><V><I><K><K><N><K><M><L><E><V><K><E><K><F><L><H><L><K><A><D><L><E><K><Q><V><S><Q><R><N><A><K><I><Q><S><V><E><T><K><L><K><Q><R><E><L><T><M><N><Q><R><Q><E><E><L><Q><R><R><N><N><E><V><E><A><V... | Endoribonuclease that initiates mRNA decay.<BOP> | A6LD62 |
A4YW84 | FABH_BRASO | 3-oxoacyl-[acyl-carrier-protein] synthase III | unclassified Bradyrhizobium | <M><T><I><R><S><V><V><L><G><C><G><S><Y><L><P><Q><R><V><V><T><N><A><E><L><A><S><R><I><E><T><S><D><E><W><I><V><Q><R><T><G><I><R><E><R><H><V><A><A><D><G><E><F><T><S><H><L><A><I><N><A><A><R><A><A><L><A><N><A><D><V><D><P><Q><S><I><D><L><I><V><L><G><T><S><T><P><D><N><T><F><P><A><T><A><V><A><V><Q><N><G><L><G><I><H><H><G><A><A... | Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-A... | A4YW84 |
Q74IQ5 | RIMM_LACJO | Ribosome maturation factor RimM | Lactobacillus | <M><T><E><Y><F><E><V><G><K><I><L><S><P><H><G><L><K><G><E><V><K><V><N><A><T><T><D><F><P><E><E><R><L><A><T><G><S><R><L><F><I><K><N><N><K><Q><Y><E><E><L><I><V><E><N><T><R><R><H><K><Q><F><Y><L><V><K><F><E><K><I><D><D><I><D><Q><A><E><K><I><C><S><K><E><L><Y><V><A><E><T><D><Q><Q><E><L><P><E><G><S><Y><Y><F><K><D><I><L><N><C><P... | An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosoma... | Q74IQ5 |
Q3SSV1 | RL6_NITWN | 50S ribosomal protein L6 | Nitrobacter | <M><S><R><I><G><K><R><P><V><T><V><P><S><G><V><T><A><T><V><E><G><Q><T><V><K><M><K><G><P><K><G><E><L><R><F><V><V><H><D><D><V><E><V><K><L><E><D><G><A><V><K><V><A><P><R><Y><E><T><K><R><A><Q><A><L><Y><G><T><A><R><A><Q><V><A><N><L><V><A><G><V><T><K><G><F><E><K><K><L><E><I><I><G><V><G><Y><R><A><A><L><Q><G><K><S><L><Q><L><A><L... | This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.<BOP> | Q3SSV1 |
A6Q4I1 | SYI_NITSB | Isoleucyl-tRNA synthetase | unclassified Nitratiruptor | <M><D><Y><K><E><T><L><L><L><P><K><T><T><F><P><M><R><G><N><L><P><Q><N><E><P><K><R><F><A><K><W><F><E><K><D><V><Y><E><K><M><K><K><S><R><E><G><K><E><L><F><T><L><H><D><G><P><P><Y><A><N><G><H><I><H><I><G><H><A><L><N><K><I><L><K><D><I><I><V><K><F><N><Y><F><E><G><K><A><V><R><F><T><P><G><W><D><C><H><G><L><P><I><E><Q><Q><V><E><K... | Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrol... | A6Q4I1 |
Q65TN4 | QUEF_MANSM | PreQ(0) reductase | Basfia | <M><D><Y><K><D><N><S><L><K><T><L><K><L><G><Q><K><T><D><Y><I><A><N><Y><D><R><T><L><L><Q><P><V><P><R><A><L><N><R><D><G><L><G><I><T><K><Q><Q><P><F><S><V><G><A><D><I><W><T><A><Y><E><I><S><W><L><N><I><K><G><L><P><Q><V><A><I><A><D><V><E><I><D><Y><R><S><T><N><L><I><E><S><K><S><F><K><L><Y><L><N><S><F><N><Q><T><K><F><S><D><M><S... | Catalyzes the NADPH-dependent reduction of 7-cyano-7-deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1).<BOP> | Q65TN4 |
Q9SII6 | PIX13_ARATH | Probable serine/threonine-protein kinase PIX13 | Arabidopsis | <M><G><L><C><W><G><S><P><S><D><S><P><P><T><T><T><P><S><S><T><G><N><I><S><S><V><G><T><F><K><S><S><N><N><T><T><T><T><G><T><S><R><G><S><N><I><S><S><N><S><G><F><S><V><A><S><G><E><D><A><Y><P><D><G><Q><I><L><P><I><P><N><L><R><I><F><S><L><A><E><L><R><A><S><T><R><N><F><R><S><E><N><V><L><G><E><G><G><F><G><K><V><F><K><G><W><L><E... | May be involved in plant defense signaling.<BOP> | Q9SII6 |
A4QKE4 | RK22_BARVE | 50S ribosomal protein L22, chloroplastic | Barbarea | <M><I><K><N><R><K><K><K><S><Y><T><S><V><Y><A><L><G><Q><Y><I><S><M><S><A><H><K><A><R><R><V><I><D><Q><I><R><G><R><S><Y><E><E><A><L><M><I><L><E><L><M><P><Y><R><G><C><Y><P><I><F><K><L><V><Y><S><A><A><A><N><A><S><H><N><K><G><F><K><E><T><N><L><V><I><S><K><A><E><V><N><Q><G><N><T><V><K><K><L><K><P><R><A><R><G><R><S><Y><P><I><K... | The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.<BOP> | A4QKE4 |
Q5SIY0 | ILVD_THET8 | Dihydroxy-acid dehydratase | Thermus | <M><R><S><D><Q><I><K><K><G><L><K><Q><A><P><A><R><A><M><L><R><A><V><G><V><G><D><E><D><F><G><R><P><F><V><G><V><V><N><T><F><T><D><G><M><P><C><N><F><H><L><R><E><L><A><Q><H><L><K><A><G><L><K><E><A><G><L><F><P><F><E><F><G><A><P><A><I><S><D><G><I><S><M><G><T><P><G><M><R><A><S><L><V><S><R><E><V><I><A><D><S><V><E><L><I><A><Q><G... | Functions in the biosynthesis of branched-chain amino acids. Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (... | Q5SIY0 |
A5TY85 | PKNA_MYCTA | Serine/threonine-protein kinase PknA | Mycobacterium tuberculosis complex | <M><S><P><R><V><G><V><T><L><S><G><R><Y><R><L><Q><R><L><I><A><T><G><G><M><G><Q><V><W><E><A><V><D><N><R><L><G><R><R><V><A><V><K><V><L><K><S><E><F><S><S><D><P><E><F><I><E><R><F><R><A><E><A><R><T><T><A><M><L><N><H><P><G><I><A><S><V><H><D><Y><G><E><S><Q><M><N><G><E><G><R><T><A><Y><L><V><M><E><L><V><N><G><E><P><L><N><S><V><L... | Protein kinase that regulates many aspects of mycobacterial physiology. Is a key component of a signal transduction pathway that regulates cell growth, cell shape and cell division via phosphorylation of target proteins such as FtsZ and MurD. Shows a strong preference for Thr versus Ser as the phosphoacceptor.<BOP> | A5TY85 |
B8CVU6 | ATPG_SHEPW | F-ATPase gamma subunit | Shewanella | <M><A><N><A><K><E><I><K><T><K><I><A><S><V><Q><N><T><Q><K><I><T><S><A><M><E><M><V><A><A><S><K><M><R><K><A><Q><D><R><M><A><S><S><R><P><Y><A><E><N><M><R><K><V><I><G><H><V><A><Q><G><S><L><E><Y><K><H><P><Y><L><E><V><R><E><A><K><R><V><G><Y><I><V><V><S><T><D><R><G><L><C><G><G><L><N><V><N><L><F><K><K><V><V><A><D><V><K><K><Q><R... | Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.<BOP> | B8CVU6 |
P49425 | MANA_RHOM4 | Endo-(1,4)-beta-mannanase | Rhodothermus | <M><T><L><L><L><V><W><L><I><F><T><G><V><A><G><E><I><R><L><E><A><E><D><G><E><L><L><G><V><A><V><D><S><T><L><T><G><Y><S><G><R><G><Y><V><T><G><F><D><A><P><E><D><S><V><R><F><S><F><E><A><P><R><G><V><Y><R><V><V><F><G><V><S><F><S><S><R><F><A><S><Y><A><L><R><V><D><D><W><H><Q><T><G><S><L><I><K><R><G><G><G><F><F><E><A><S><I><G><E... | Acts as endo-acting enzyme with a requirement for at least five sugar moieties for effective catalytic activity. Hydrolyzes carob-galactomannan (locust bean gum) effectively and to a smaller extent guar gum, but not yeast mannan.<BOP> | P49425 |
Q96M95 | CCD42_HUMAN | Coiled-coil domain-containing protein 42 | Homo | <M><S><L><G><I><M><E><E><E><D><L><A><E><Y><F><R><L><Q><Y><G><E><R><L><L><Q><M><L><Q><K><L><P><N><V><E><G><A><S><E><S><P><S><I><W><L><L><E><K><K><K><E><T><E><I><M><H><Q><T><M><V><Q><K><K><K><M><F><Q><R><R><M><E><T><L><N><L><R><W><E><E><L><G><V><K><E><A><Q><L><K><A><H><I><Q><K><S><E><Q><F><I><Q><E><N><D><Q><K><R><I><R><A... | Required for sperm development.<BOP> | Q96M95 |
Q09LL3 | BBD_ORYMI | Bifunctional nuclease | Oryza | <M><E><I><I><N><G><P><V><L><P><R><Y><A><A><P><A><T><G><A><L><T><S><D><A><K><I><S><G><Q><L><L><R><R><V><H><L><R><R><R><A><C><G><L><Q><G><D><H><Y><R><A><A><R><R><F><F><G><F><P><S><E><R><H><A><R><S><G><W><V><W><P><V><Y><C><S><Y><G><S><S><S><D><G><D><G><A><A><A><A><D><Y><D><A><S><G><E><E><F><V><N><S><S><V><M><E><A><V><E><L... | Bifunctional nuclease with both RNase and DNase activities. Involved in basal defense response. Participates in abscisic acid-derived callose deposition following infection by a necrotrophic pathogen.<BOP> | Q09LL3 |
Q92GL2 | COAE_RICCN | Dephosphocoenzyme A kinase | spotted fever group | <M><L><A><I><G><I><T><G><S><Y><A><S><G><K><T><F><M><L><D><Y><L><T><E><K><G><Y><K><T><F><C><A><D><R><C><I><K><E><L><Y><Q><D><V><V><L><Q><T><Q><I><L><K><L><L><P><E><L><E><S><F><N><I><R><K><I><S><N><L><I><Y><N><N><D><L><A><R><E><K><L><Q><N><F><I><Y><P><L><L><I><D><K><L><I><L><F><K><K><E><N><A><N><S><K><F><G><F><A><E><I><P... | Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A.<BOP> | Q92GL2 |
Q1DC68 | NFI_MYXXD | Deoxyribonuclease V | Myxococcus | <M><C><M><A><L><Q><P><E><V><S><R><W><D><V><T><P><S><E><A><V><E><L><Q><R><R><L><R><E><Q><L><V><L><R><P><P><P><G><L><K><V><E><R><I><A><G><A><D><I><S><T><E><K><G><K><D><T><G><F><G><G><F><V><V><L><D><V><E><T><L><A><P><V><A><Q><S><E><A><V><V><T><L><H><F><P><Y><V><P><G><L><L><S><F><R><E><L><P><T><I><A><A><A><W><E><R><L><T><V... | DNA repair enzyme involved in the repair of deaminated bases. Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA.<BOP> | Q1DC68 |
O67353 | PYRG_AQUAE | UTP--ammonia ligase | Aquifex | <M><A><K><Y><I><F><I><T><G><G><V><L><S><S><L><G><K><G><I><T><S><A><S><I><A><S><I><L><E><E><M><G><Y><R><V><T><L><Q><K><L><D><P><Y><L><N><V><D><A><G><T><M><S><P><Y><Q><H><G><E><V><Y><V><T><E><D><G><A><E><T><D><L><D><L><G><H><Y><E><R><F><T><N><A><V><M><T><R><D><N><N><V><T><A><G><R><I><Y><Y><N><V><I><S><K><E><R><K><G><D><Y... | Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.<BOP> | O67353 |
Q9KPG9 | FTSQ_VIBCH | Cell division protein FtsQ | Vibrio | <M><I><N><K><V><L><L><E><G><Q><R><I><T><R><S><P><Q><V><K><Q><H><A><C><G><A><S><F><F><L><V><V><L><L><L><I><G><G><L><L><Y><S><T><I><S><W><M><W><D><E><Q><R><L><P><L><S><K><L><V><L><Q><G><D><L><H><Y><V><S><A><L><D><V><Q><R><V><L><A><R><L><D><H><I><G><T><F><M><S><Q><D><I><N><V><L><Q><E><S><V><Q><S><I><P><W><V><S><H><A><S><I... | Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly.<BOP> | Q9KPG9 |
Q9ST43 | PH1_ARATH | Pleckstrin homology domain-containing protein 1 | Arabidopsis | <M><E><S><I><W><R><I><A><T><G><Q><D><P><S><R><E><D><Y><E><G><I><E><F><W><S><N><P><E><R><S><G><W><L><T><K><Q><G><D><Y><I><K><T><W><R><R><R><W><F><V><L><K><R><G><K><L><L><W><F><K><D><Q><A><A><A><G><I><R><G><S><T><P><R><G><V><I><S><V><G><D><C><L><T><V><K><G><A><E><D><V><V><N><K><P><F><A><F><E><L><S><S><G><S><Y><T><M><F><F... | Binds specifically to phosphatidylinositol 3-phosphate (PtdIns3P), but not to other phosphoinositides.<BOP> | Q9ST43 |
B5VS52 | SEY1_YEAS6 | Synthetic enhancer of YOP1 protein | Saccharomyces | <M><A><D><R><S><A><I><Q><L><I><D><E><E><K><E><F><H><Q><S><A><L><Q><Y><F><Q><Q><C><I><G><N><R><D><V><G><L><D><Y><H><V><I><S><V><F><G><S><Q><S><S><G><K><S><T><L><L><N><V><L><F><N><T><N><F><D><T><M><D><A><Q><V><K><R><Q><Q><T><T><K><G><I><W><L><A><H><T><K><Q><V><N><T><T><I><E><I><D><N><D><R><P><D><I><F><V><L><D><V><E><G><S... | Cooperates with the reticulon proteins RTN1 and RTN2 and the tubule-shaping DP1 family protein YOP1 to generate and maintain the structure of the tubular endoplasmic reticulum network. Has GTPase activity, which is required for its function in ER organization.<BOP> | B5VS52 |
A8YXI3 | ALR_LACH4 | Alanine racemase | Lactobacillus | <M><V><P><G><Y><Y><R><P><A><V><V><K><V><N><L><G><A><I><R><R><N><I><K><N><E><M><Q><H><L><E><P><N><Q><K><M><L><A><V><V><K><A><N><G><Y><G><H><G><A><V><E><V><A><K><V><A><E><E><E><G><A><A><G><F><C><V><A><I><L><D><E><A><L><E><L><R><R><A><D><I><V><K><P><I><L><V><L><G><V><V><S><P><E><Y><A><P><I><A><A><V><N><N><V><S><L><T><V><P... | Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids.<BOP> | A8YXI3 |
O23731 | CHS8_BROFI | Naringenin-chalcone synthase 8 | Bromheadia | <M><A><P><A><M><E><E><I><R><Q><A><Q><R><A><E><G><P><A><A><V><L><A><I><G><T><S><T><P><P><N><A><L><Y><Q><A><D><Y><P><D><Y><Y><F><R><I><T><K><S><E><H><L><T><E><L><K><E><K><F><K><R><M><C><D><K><S><M><I><K><K><R><Y><M><Y><L><T><E><E><I><L><K><E><N><P><N><I><C><A><F><M><A><P><S><L><D><A><R><Q><D><I><V><V><T><E><V><P><K><L><A... | The primary product of this enzyme is 4,2',4',6'-tetrahydroxychalcone (also termed naringenin-chalcone or chalcone) which can under specific conditions spontaneously isomerize into naringenin.<BOP> | O23731 |
A8AGR7 | SOTB_CITK8 | Probable sugar efflux transporter | Citrobacter | <M><T><T><N><T><V><S><R><K><V><A><W><L><R><V><V><T><L><A><I><A><A><F><I><F><N><T><T><E><F><V><P><V><G><L><L><S><D><I><A><R><S><F><A><M><P><T><A><Q><V><G><I><M><L><T><I><Y><A><W><V><V><A><L><M><S><L><P><F><M><L><L><T><S><Q><V><E><R><R><K><L><L><I><C><L><F><V><L><F><I><A><S><H><V><L><S><F><L><A><W><N><F><T><V><L><V><I><S... | Involved in the efflux of sugars. The physiological role may be the reduction of the intracellular concentration of toxic sugars or sugar metabolites.<BOP> | A8AGR7 |
P33775 | PMT1_YEAST | Dolichyl-phosphate-mannose--protein mannosyltransferase 1 | Saccharomyces | <M><S><E><E><K><T><Y><K><R><V><E><Q><D><D><P><V><P><E><L><D><I><K><Q><G><P><V><R><P><F><I><V><T><D><P><S><A><E><L><A><S><L><R><T><M><V><T><L><K><E><K><L><L><V><A><C><L><A><V><F><T><A><V><I><R><L><H><G><L><A><W><P><D><S><V><V><F><D><E><V><H><F><G><G><F><A><S><Q><Y><I><R><G><T><Y><F><M><D><V><H><P><P><L><A><K><M><L><Y><A... | Protein O-mannosyltransferase involved in O-glycosylation which is essential for cell wall rigidity. Forms a heterodimeric complex with PMT2 and more rarely with PMT3 to transfer mannose from Dol-P-mannose to Ser or Thr residues on proteins. The PMT1-PMT2 complex participates in oxidative protein folding, ER-associated... | P33775 |
A9WAN7 | MINE_CHLAA | Cell division topological specificity factor | Chloroflexus | <M><S><F><L><N><G><L><F><G><R><K><R><D><S><S><A><E><L><A><K><Q><R><L><L><T><V><L><I><D><D><R><Y><K><L><T><P><E><M><M><A><Q><M><K><A><D><L><A><E><V><L><K><R><Y><L><P><A><I><D><A><E><Q><I><E><V><T><L><S><R><G><E><A><H><D><L><L><K><A><D><V><P><L><R><R><A><T><D><H><P><P><N><R> | Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell.<BOP> | A9WAN7 |
Q49939 | PAPA5_MYCLE | Polyketide synthase-associated protein A5 | Mycobacterium | <M><F><A><G><S><V><I><R><K><L><S><H><S><E><E><V><F><A><R><Y><E><V><F><T><S><M><T><I><Q><L><R><G><V><L><D><I><D><A><L><S><E><A><F><D><A><L><V><Q><A><H><P><V><L><A><S><H><L><E><T><S><S><D><G><G><W><N><L><V><A><D><D><L><L><H><P><G><I><C><V><V><D><A><N><N><G><A><Q><S><G><C><G><G><I><Q><S><E><T><R><L><D><Q><S><V><S><L><L><N... | Catalyzes diesterification of phthiocerol, phthiodiolone, and phenolphthiocerol with mycocerosic acids, the final step in the phthiocerol, phthiodiolone and phenolphthiocerol dimycocerosate esters (PDIM) synthesis. Can directly transfer the mycocerosate bound to the mycocerosic acid synthase (mas) onto the substrate al... | Q49939 |
P47533 | P69_MYCGE | ABC transport system permease protein p69 | Mycoplasma | <M><I><T><K><L><F><F><H><Q><V><G><D><N><K><K><R><L><I><W><Y><W><K><L><L><I><I><I><A><V><L><A><I><V><I><Y><S><W><I><D><N><F><S><S><F><N><Q><F><G><L><N><V><F><I><N><N><I><T><S><L><F><T><P><N><L><N><H><E><Y><T><L><V><R><F><L><A><Q><T><A><F><F><V><T><G><G><S><F><L><G><F><I><F><A><I><L><F><S><Y><W><T><A><F><K><I><Q><P><F><Y... | Probably part of a high-affinity transport system.<BOP> | P47533 |
B9MS73 | ATPL_CALBD | Lipid-binding protein | Caldicellulosiruptor | <M><T><A><L><A><A><G><I><A><M><L><A><G><L><G><V><G><I><G><I><G><I><A><T><G><K><A><S><E><S><I><G><R><Q><P><E><A><F><G><R><I><F><P><L><F><L><I><G><A><A><L><A><E><A><V><A><I><Y><S><L><V><I><A><F><M><L><I><S><K><I> | Key component of the F(0) channel; it plays a direct role in translocation across the membrane. A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.<BOP> | B9MS73 |
B4SW31 | PPNP_SALNS | Xanthosine phosphorylase | Salmonella | <M><L><Q><S><N><E><Y><F><S><G><K><V><K><S><I><G><F><T><S><S><S><I><G><R><A><S><V><G><V><M><A><E><G><E><Y><T><F><G><T><A><E><P><E><E><M><T><V><V><S><G><A><L><K><V><L><L><P><G><T><V><E><W><K><V><Y><T><A><G><E><V><F><N><V><P><G><H><S><E><F><H><L><Q><V><A><E><P><T><S><Y><L><C><R><Y><L> | Catalyzes the phosphorolysis of diverse nucleosides, yielding D-ribose 1-phosphate and the respective free bases. Can use uridine, adenosine, guanosine, cytidine, thymidine, inosine and xanthosine as substrates. Also catalyzes the reverse reactions.<BOP> | B4SW31 |
P9WJ40 | VPB24_MYCTO | Putative antitoxin VapB24 | Mycobacterium tuberculosis complex | <M><I><R><T><Q><V><Q><L><P><D><E><L><Y><R><D><A><K><R><V><A><H><E><H><E><M><T><L><A><E><V><V><R><R><G><L><E><H><M><V><R><I><Y><P><R><R><D><A><A><S><D><T><W><Q><P><P><T><P><R><R><L><G><P><F><R><A><S><E><E><T><W><R><E><L><A><N><E><A> | Possibly the antitoxin component of a type II toxin-antitoxin (TA) system. Its cognate toxin is VapC24 (Potential).<BOP> | P9WJ40 |
Q90W58 | DUS1B_XENLA | XCL100-beta | Xenopus | <M><V><N><M><E><I><C><A><M><D><C><C><V><F><K><G><L><L><A><E><R><A><H><K><C><L><I><L><D><C><R><S><F><F><A><F><S><S><S><S><I><I><G><S><S><N><V><R><L><S><T><I><V><K><R><R><A><K><G><S><M><G><L><E><H><I><I><P><N><E><E><Q><R><G><R><L><V><A><G><M><Y><E><A><V><V><L><L><D><E><R><T><S><E><L><D><M><L><R><K><D><S><T><M><M><L><A><V... | Dual specificity phosphatase that dephosphorylates MAP kinase MAPK1/ERK2 on both 'Thr-188' and 'Tyr-190', regulating its activity during the meiotic cell cycle.<BOP> | Q90W58 |
B0WAU6 | LIAS_CULQU | Lipoic acid synthase | Culex | <M><K><Y><F><F><S><L><P><F><P><K><V><H><T><T><C><K><H><T><A><A><A><T><A><S><Q><P><L><Q><K><I><R><E><R><L><E><S><G><P><G><F><Q><E><F><V><Q><N><P><S><Y><N><R><E><D><W><S><A><Y><E><G><K><L><K><R><E><K><G><E><Q><D><R><L><R><L><P><P><W><L><K><T><K><I><P><M><G><K><N><F><S><R><I><K><D><Q><L><R><E><L><K><L><A><T><V><C><E><E><A... | Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.<BOP> | B0WAU6 |
B7VGI4 | DNAA_VIBA3 | Chromosomal replication initiator protein DnaA | Vibrio | <M><S><S><S><L><W><L><Q><C><L><Q><Q><L><Q><E><E><L><P><A><T><E><F><S><M><W><V><R><P><L><Q><A><E><L><N><G><N><T><L><T><L><F><A><P><N><R><F><V><L><D><W><V><R><D><K><Y><L><N><S><I><N><R><L><L><Q><E><Y><C><G><N><D><I><P><H><L><H><F><E><I><G><N><K><R><V><T><A><P><K><S><E><T><I><A><P><A><R><T><R><T><A><A><D><V><A><A><E><S><S... | Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids.<BOP> | B7VGI4 |
P20247 | HBB2_TORMA | Hemoglobin beta-2 chain | Torpedo | <V><S><L><T><D><E><E><K><H><L><I><Q><H><I><W><S><N><V><N><V><V><E><I><T><A><K><A><L><E><R><V><F><Y><V><Y><P><W><T><T><R><L><F><T><S><F><N><H><N><F><K><A><S><D><K><G><V><H><D><H><A><V><N><V><S><K><A><L><S><A><A><I><G><D><L><H><N><V><N><K><N><F><S><A><L><S><T><K><H><Q><K><K><L><G><V><D><T><S><N><F><M><L><L><G><Q><A><F><L... | Involved in oxygen transport from the lung to the various peripheral tissues.<BOP> | P20247 |
Q6A6A0 | NANE_CUTAK | ManNAc-6-P epimerase | Cutibacterium | <M><S><G><F><T><D><R><I><I><A><S><M><A><G><G><L><V><V><S><C><Q><A><Y><P><G><E><P><L><R><H><P><E><T><M><A><Q><M><A><A><A><V><E><A><G><G><A><V><A><V><R><A><Q><G><L><S><D><V><S><A><V><K><G><R><V><S><V><P><V><V><G><I><W><K><E><G><D><E><G><I><Y><I><T><P><T><L><R><H><A><R><C><V><S><A><A><G><A><D><V><V><A><L><D><G><T><R><R><E... | Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P).<BOP> | Q6A6A0 |
B9JXN7 | PDXJ_AGRVS | Pyridoxine 5'-phosphate synthase | Agrobacterium | <M><P><A><K><L><S><V><N><L><N><A><I><A><M><L><R><N><R><R><D><L><P><W><P><D><V><R><H><F><G><R><L><A><L><Q><A><G><A><Q><G><L><T><V><H><P><R><P><D><Q><R><H><V><R><F><S><D><L><P><L><L><R><A><L><I><D><D><E><F><P><K><A><E><F><N><I><E><G><Y><P><S><E><D><F><L><Q><L><C><E><E><A><Q><P><E><Q><V><T><L><V><P><D><D><P><S><Q><A><T><S... | Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate.<BOP> | B9JXN7 |
A0A5C1RD96 | ASC5_DIDFA | Ascochitine biosynthesis cluster protein 5 | Ascochyta | <M><P><H><R><L><P><S><H><G><A><S><L><G><L><I><F><G><P><Q><A><M><N><F><D><S><N><T><F><T><T><L><R><A><K><L><V><K><D><R><H><S><Q><W><A><I><D><A><I><A><A><L><P><A><E><W><S><A><V><S><G><N><V><A><I><F><K><Q><Y><D><A><G><K><A><L><Q><N><L><N><E><W><L><K><T><G><H><V><P><P><A><D><I><P><F><C><N><V><L><L><A><P><M><V><V><I><D><H><V... | Non-reducing polyketide synthase; part of the gene cluster that mediates the biosynthesis of the selective antifungal agent ascochitine, an o-quinone methide that plays a possible protective role against other microbial competitors in nature and is considered to be important for pathogenicity of legume-associated Didym... | A0A5C1RD96 |
Q65DY4 | FDHD_BACLD | Sulfur carrier protein FdhD | Bacillus | <M><G><K><N><I><T><T><S><R><K><I><F><R><Y><D><N><G><E><L><V><Q><Q><E><D><Q><M><A><T><E><F><P><L><T><V><M><V><N><G><E><E><F><V><T><L><V><C><S><P><D><S><L><E><E><L><V><I><G><F><L><A><S><E><G><V><I><R><F><K><N><E><I><K><R><F><T><I><D><E><S><L><G><F><A><Y><V><D><L><V><S><T><K><K><L><Q><L><K><D><Y><T><K><R><V><I><G><S><C><C... | Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH.<BOP> | Q65DY4 |
Q8YP62 | EFG_NOSS1 | Elongation factor G | Nostoc | <M><A><R><I><N><P><L><E><K><V><R><N><I><G><I><A><A><H><I><D><A><G><K><T><T><T><T><E><R><I><L><F><Y><S><G><I><I><H><K><I><G><E><V><H><E><G><T><A><V><T><D><W><M><D><Q><E><R><E><R><G><I><T><I><T><A><A><A><I><S><T><S><W><K><D><Y><Q><I><N><I><I><D><T><P><G><H><V><D><F><T><I><E><V><E><R><S><M><R><V><L><D><G><V><I><A><V><F><C... | Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respective... | Q8YP62 |
Q5GSI3 | SYE2_WOLTR | Glutamyl-tRNA synthetase 2 | unclassified Wolbachia | <M><P><N><I><V><T><R><F><A><P><S><P><T><G><F><L><H><I><G><G><A><R><T><A><L><F><N><W><L><Y><A><K><H><H><G><G><R><F><L><L><R><I><E><D><T><D><R><K><R><S><T><Q><E><A><I><D><A><I><I><N><G><L><K><W><L><G><V><S><Y><D><G><E><I><V><Y><Q><S><K><R><I><E><R><H><I><E><V><A><N><L><L><V><E><K><G><K><A><Y><C><C><C><C><P><E><D><K><V><A... | Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).<BOP> | Q5GSI3 |
Q6NMR8 | FAF3_ARATH | Protein FANTASTIC FOUR 3 | Arabidopsis | <M><G><T><V><V><Y><Q><Q><G><F><Q><S><Q><L><N><E><P><R><A><L><R><L><R><L><S><S><P><N><P><H><F><S><Q><P><F><G><L><A><L><K><S><H><L><L><D><S><S><H><A><E><D><T><R><N><R><N><D><D><K><A><A><A><S><P><V><S><D><S><S><G><W><S><S><L><Q><S><L><S><S><G><S><S><S><S><T><K><T><T><T><S><S><E><K><E><S><S><Y><Y><V><Q><R><P><S><S><C><R><A... | Able to repress WUS when constitutively overexpressed, but have no effect on CLV3.<BOP> | Q6NMR8 |
Q6YR94 | CH60_ONYPE | Chaperonin-60 | Candidatus Phytoplasma asteris | <M><S><K><K><I><L><Y><G><K><E><A><R><K><A><L><L><Q><G><V><D><A><I><A><N><T><V><K><V><T><L><G><P><K><G><R><N><V><I><L><E><K><A><Y><D><S><P><A><I><V><N><D><G><V><S><I><A><K><E><I><E><L><K><N><P><Y><Q><N><M><G><A><K><L><V><Y><E><V><A><S><K><T><N><D><K><A><G><D><G><T><T><T><A><T><V><L><A><Q><S><M><I><H><R><G><F><D><A><I><D... | Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.<BOP> | Q6YR94 |
O22666 | RGP3_ARATH | UDP-L-arabinose mutase 3 | Arabidopsis | <M><A><Q><L><Y><S><S><V><K><P><T><P><M><L><K><D><E><L><D><I><V><I><P><T><I><R><N><L><D><F><L><E><M><W><R><P><F><F><E><Q><Y><H><L><I><I><V><Q><D><G><D><P><S><K><V><I><N><I><P><V><G><F><D><Y><E><L><Y><N><R><N><D><I><N><R><I><L><G><P><K><A><S><C><I><S><F><K><D><S><A><C><R><C><F><G><Y><M><V><S><K><K><K><Y><I><Y><T><I><D><D... | UDP-L-arabinose mutase involved in the biosynthesis of cell wall non-cellulosic polysaccharides. Catalyzes the interconvertion of UDP-L-arabinopyranose (UDP-Arap) and UDP-L-arabinofuranose (UDP-Araf). Preferentially catalyzes the formation of UDP-Arap from UDP-Araf. At thermodynamic equilibrium in vitro the ratio of th... | O22666 |
B0T2B5 | EFTU2_CAUSK | Elongation factor Tu 2 | unclassified Caulobacter | <M><A><K><E><K><F><E><R><N><K><P><H><C><N><I><G><T><I><G><H><V><D><H><G><K><T><T><L><T><A><A><I><T><I><I><L><A><K><S><G><G><A><T><A><K><N><Y><A><D><I><D><A><A><P><E><E><K><A><R><G><I><T><I><N><T><A><H><V><E><Y><E><T><A><N><R><H><Y><A><H><V><D><C><P><G><H><A><D><Y><V><K><N><M><I><T><G><A><A><Q><M><D><G><A><I><L><V><V><S... | This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.<BOP> | B0T2B5 |
Q1R1C8 | DCUP_CHRSD | Uroporphyrinogen decarboxylase | Chromohalobacter | <M><P><L><Q><N><D><R><L><L><R><A><L><A><R><Q><P><V><D><R><T><P><V><W><M><M><R><Q><A><G><R><Y><L><P><E><Y><R><E><T><R><G><Q><A><G><S><F><M><D><L><C><R><N><A><E><L><A><C><E><V><T><M><Q><P><L><R><R><Y><A><L><D><A><A><I><L><F><S><D><I><L><T><I><P><D><A><M><D><L><G><L><Y><F><E><T><G><E><G><P><K><F><R><K><T><V><R><S><A><E><A... | Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.<BOP> | Q1R1C8 |
A0KT03 | MURA_SHESA | UDP-N-acetylglucosamine enolpyruvyl transferase | Shewanella | <M><D><K><L><A><I><Q><A><S><P><P><L><A><G><D><V><I><I><S><G><A><K><N><A><A><L><P><I><L><M><A><G><V><L><A><E><T><D><F><I><V><S><N><V><P><N><L><R><D><V><S><T><S><C><K><L><L><R><C><L><G><A><D><V><D><E><L><G><N><G><Q><I><R><I><S><T><K><N><L><N><E><F><C><A><P><Y><D><L><V><K><T><M><R><A><S><I><L><I><L><G><P><L><L><A><R><Y><G... | Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine.<BOP> | A0KT03 |
B1ZDT1 | DAPF_METPB | PLP-independent amino acid racemase | Methylorubrum | <M><S><P><L><A><N><R><R><F><L><K><M><H><G><A><G><N><A><I><V><V><L><D><L><R><G><T><S><I><R><V><A><P><A><E><A><R><A><I><A><A><D><A><H><S><R><F><D><Q><L><M><V><V><H><D><P><V><T><P><G><T><D><A><F><M><R><I><Y><N><T><D><G><S><E><S><G><A><C><G><N><G><T><R><C><V><G><Y><A><L><L><D><D><P><A><M><A><R><P><A><E><N><G><C><L><T><L><E... | Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan.<BOP> | B1ZDT1 |
A3CNV3 | AROA_STRSV | 5-enolpyruvylshikimate-3-phosphate synthase | Streptococcus | <M><K><L><S><T><N><V><K><G><L><K><G><R><I><R><V><P><G><D><K><S><I><S><H><R><S><I><I><F><G><S><L><A><K><G><V><T><T><V><R><D><I><L><R><G><E><D><V><L><S><T><M><Q><V><F><R><D><L><G><V><Q><I><E><D><D><G><N><L><V><K><I><H><G><V><G><F><E><G><L><Q><A><P><K><N><K><L><D><M><G><N><S><G><T><S><I><R><L><I><S><G><V><L><A><G><Q><D><F... | Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.<BOP> | A3CNV3 |
Q2GGA2 | TRUB_EHRCR | tRNA-uridine isomerase | Ehrlichia | <M><Y><G><W><I><N><L><D><K><P><C><G><I><S><S><A><S><A><V><N><L><V><K><K><I><L><N><V><K><K><V><G><H><A><G><T><L><D><P><L><A><S><G><V><L><P><I><A><I><G><E><A><T><K><V><M><P><Y><A><V><D><V><V><K><S><Y><L><F><T><V><Q><W><G><E><Q><R><T><T><D><D><I><E><G><K><I><V><A><K><S><D><I><V><P><S><S><E><D><I><K><K><A><I><P><N><F><I><G... | Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.<BOP> | Q2GGA2 |
Q4UKF2 | GATC_RICFE | Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit C | spotted fever group | <M><I><T><K><E><E><A><Q><K><I><A><K><L><A><R><L><K><F><E><E><D><T><V><E><K><F><S><A><Q><L><S><T><I><M><N><M><I><D><I><L><N><E><I><D><C><K><D><I><E><P><L><T><S><V><S><N><M><N><V><R><M><R><E><D><V><V><T><S><S><D><L><S><N><K><L><F><D><N><V><S><G><N><S><A><Q><L><A><K><E><V><K><Y><F><I><T><P><K><V><I><E> | Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated ... | Q4UKF2 |
Q9H5I1 | SUV92_HUMAN | Suppressor of variegation 3-9 homolog 2 | Homo | <M><A><A><V><G><A><E><A><R><G><A><W><C><V><P><C><L><V><S><L><D><T><L><Q><E><L><C><R><K><E><K><L><T><C><K><S><I><G><I><T><K><R><N><L><N><N><Y><E><V><E><Y><L><C><D><Y><K><V><V><K><D><M><E><Y><Y><L><V><K><W><K><G><W><P><D><S><T><N><T><W><E><P><L><Q><N><L><K><C><P><L><L><L><Q><Q><F><S><N><D><K><H><N><Y><L><S><Q><V><K><K><G... | Histone methyltransferase that specifically trimethylates 'Lys-9' of histone H3 using monomethylated H3 'Lys-9' as substrate. H3 'Lys-9' trimethylation represents a specific tag for epigenetic transcriptional repression by recruiting HP1 (CBX1, CBX3 and/or CBX5) proteins to methylated histones. Mainly functions in hete... | Q9H5I1 |
P45584 | CU63_LOCMI | LM-ACP 63 | Locusta | <G><L><L><G><L><G><Y><G><G><Y><S><G><Y><G><G><Y><G><G><Y><G><H><G><L><A><L><A><A><A><P><A><A><I><A><A><P><A><V><V><A><A><P><A><I><A><H><A><P><A><V><A><V><A><P><A><V><A><H><A><P><A><A><V><S><T><V><S><Q><V><S><Y><G><T><T><H><Y><A><P><A><V><A><K><V><A><A><A><P><V><A><V><A><A><P><A><I><A><A><A><P><A><I><A><A><A><P><A><V><G... | Component of the cuticle of migratory locust which contains more than 100 different structural proteins.<BOP> | P45584 |
A8GKQ1 | CYSG2_SERP5 | Sirohydrochlorin ferrochelatase 2 | Serratia | <M><D><Y><L><P><I><F><C><Q><L><Q><H><K><A><C><L><L><V><G><G><G><E><I><A><E><R><K><A><R><L><L><L><D><A><G><A><A><L><T><V><N><A><C><S><F><T><P><Q><F><H><E><W><A><A><L><G><R><L><T><L><A><A><G><E><F><S><A><E><L><L><A><E><K><W><L><V><I><A><A><T><D><R><V><E><V><N><A><L><V><Y><Q><C><A><N><Q><Q><R><V><F><C><N><V><V><D><D><P><K... | Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yie... | A8GKQ1 |
P00430 | COX7C_BOVIN | Cytochrome c oxidase polypeptide VIIc | Bos | <M><L><G><Q><S><I><R><R><F><T><T><S><V><V><R><R><S><H><Y><E><E><G><P><G><K><N><I><P><F><S><V><E><N><K><W><R><L><L><A><M><M><T><L><F><F><G><S><G><F><A><A><P><F><F><I><V><R><H><Q><L><L><K><K> | Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CII... | P00430 |
B4SKH7 | DEF_STRM5 | Polypeptide deformylase | Stenotrophomonas maltophilia group | <M><A><L><L><P><I><L><E><F><P><D><P><R><L><R><T><K><A><A><L><I><D><A><A><E><V><T><T><P><A><F><Q><E><L><V><D><N><M><F><Q><T><M><Y><D><A><P><G><I><G><L><A><A><T><Q><V><D><V><H><K><R><F><M><V><I><D><V><S><E><E><K><N><E><P><H><V><F><I><N><P><E><I><V><A><K><D><G><G><R><V><Y><Q><E><G><C><L><S><V><P><G><I><F><A><D><V><T><R><A... | Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.<BOP> | B4SKH7 |
O31041 | PDUD_SALTY | Propanediol utilization protein PduD | Salmonella | <M><E><I><N><E><K><L><L><R><Q><I><I><E><D><V><L><R><D><M><K><G><S><D><K><P><V><S><F><N><A><P><A><A><S><T><A><P><Q><T><A><A><P><A><G><D><G><F><L><T><E><V><G><E><A><R><Q><G><T><Q><Q><D><E><V><I><I><A><V><G><P><A><F><G><L><A><Q><T><V><N><I><V><G><L><P><H><K><S><I><L><R><E><V><I><A><G><I><E><E><E><G><I><K><A><R><V><I><R><C... | The 1,2-PD-specific bacterial microcompartment (BMC) concentrates low levels of 1,2-PD catabolic enzymes, concentrates volatile reaction intermediates thus enhancing pathway flux and keeps the level of toxic, mutagenic propionaldehyde low.<BOP> | O31041 |
B2FN89 | RBFA_STRMK | Ribosome-binding factor A | Stenotrophomonas maltophilia group | <M><P><K><T><F><H><R><T><D><R><V><S><A><Q><L><R><R><E><L><G><T><L><V><H><N><A><V><R><E><H><G><L><P><S><V><S><V><S><D><V><E><I><T><R><D><M><A><H><A><K><V><F><V><T><A><L><M><P><E><R><S><A><E><A><V><A><G><L><K><E><L><G><Y><R><L><R><M><D><L><A><R><A><M><K><L><R><H><V><P><E><L><H><F><H><Y><D><D><S><V><D><R><G><E><H><I><D><N... | One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal heli... | B2FN89 |
A1SRP9 | CYSG_PSYIN | Sirohydrochlorin ferrochelatase | Psychromonas | <M><D><Y><L><P><I><F><T><K><L><E><N><R><P><C><L><V><V><G><G><G><S><I><A><C><R><K><I><H><L><L><L><K><A><G><A><D><V><T><V><C><A><L><E><F><N><P><S><L><L><K><Q><A><A><N><K><E><L><K><I><L><E><Q><A><F><T><E><E><L><L><E><N><K><W><L><V><I><A><A><T><N><K><K><Q><V><N><E><H><I><A><T><A><A><H><A><K><Q><L><L><V><N><V><V><G><Q><A><D... | Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yie... | A1SRP9 |
B0JS46 | UREF_MICAN | Urease accessory protein UreF | Microcystis | <M><L><D><Q><K><E><L><L><C><L><L><Q><L><A><S><P><I><L><P><V><G><A><Y><S><Y><S><E><G><L><E><T><L><V><E><K><G><I><I><S><N><S><A><S><L><N><D><W><L><E><R><S><L><C><Q><G><S><I><R><L><E><T><A><V><L><L><R><V><Y><R><C><F><C><Q><E><D><F><T><K><L><N><Y><W><D><N><W><L><S><A><T><R><E><T><A><E><L><R><Q><Q><S><W><Q><M><G><R><S><L><L... | Required for maturation of urease via the functional incorporation of the urease nickel metallocenter.<BOP> | B0JS46 |
B1J5D6 | TUSA_PSEPW | Sulfur carrier protein TusA | Pseudomonas | <M><T><D><F><T><P><D><A><I><L><D><A><T><G><L><N><C><P><E><P><V><M><M><L><H><T><H><V><R><N><L><A><A><G><G><L><L><K><V><I><A><T><D><P><S><T><R><R><D><I><P><K><F><C><N><F><L><G><H><E><L><L><Q><Q><Q><E><E><A><G><T><Y><L><Y><W><I><R><K><K><A><D> | Sulfur carrier protein which probably makes part of a sulfur-relay system.<BOP> | B1J5D6 |
Q89A13 | YFGM_BUCBP | Chaperone YfgM | Buchnera | <M><I><K><N><S><Y><I><N><E><K><L><N><F><Y><Q><K><S><F><L><T><C><M><L><L><I><V><I><V><I><V><Y><F><F><S><K><N><Y><L><D><K><P><K><N><S><Y><V><H><T><K><M><M><T><F><L><T><N><S><N><E><L><N><I><S><K><N><L><I><W><T><K><K><T><I><S><G><N><L><M><S><L><K><L><A><K><V><Y><V><I><N><N><Q><L><E><K><A><L><K><I><L><E><K><S><K><N><N><S><V... | May mediate protein transfer from the Sec translocon to the chaperone network via its extracellular C-terminal region.<BOP> | Q89A13 |
B2SHB9 | ALR_FRATM | Alanine racemase | Francisella | <M><N><I><L><K><I><S><K><Q><T><L><R><N><N><I><K><I><I><R><E><Y><I><G><N><A><K><M><C><F><P><V><K><A><N><A><Y><G><H><G><I><E><D><I><V><E><N><T><H><D><L><V><D><F><F><A><V><A><N><S><L><E><A><F><R><V><T><A><V><A><K><N><P><V><L><V><F><G><V><I><Y><Y><E><Y><I><E><K><M><I><S><E><N><I><R><V><S><I><Q><D><Y><E><D><I><E><K><L><E><Q... | Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids.<BOP> | B2SHB9 |
A7ZTI5 | COAD_ECO24 | Pantetheine-phosphate adenylyltransferase | Escherichia | <M><Q><K><R><A><I><Y><P><G><T><F><D><P><I><T><N><G><H><I><D><I><V><T><R><A><T><Q><M><F><D><H><V><I><L><A><I><A><A><S><P><S><K><K><P><M><F><T><L><E><E><R><V><A><L><A><Q><Q><A><T><A><H><L><G><N><V><E><V><V><G><F><S><D><L><M><A><N><F><A><R><N><Q><H><A><T><V><L><I><R><G><L><R><A><V><A><D><F><E><Y><E><M><Q><L><A><H><M><N><R... | Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.<BOP> | A7ZTI5 |
Q5WCP7 | HUTU_ALKCK | Imidazolonepropionate hydrolase | Alkalihalobacillus | <M><N><L><N><N><E><P><I><R><A><K><R><G><T><A><L><T><A><K><G><W><V><Q><E><A><A><L><R><M><L><M><N><N><L><D><E><E><V><A><E><H><P><D><Q><L><V><V><Y><G><G><I><G><K><A><A><R><N><W><P><S><Y><H><S><I><V><S><S><L><T><T><L><D><N><D><E><T><L><L><I><Q><S><G><K><P><V><A><V><F><K><T><H><E><D><A><P><R><V><L><L><A><N><S><N><L><V><P><A... | Catalyzes the conversion of urocanate to 4-imidazolone-5-propionate.<BOP> | Q5WCP7 |
Q9Y3R5 | DOP2_HUMAN | Protein dopey-2 | Homo | <M><D><P><E><E><Q><E><L><L><N><D><Y><R><Y><R><S><Y><S><S><V><I><E><K><A><L><R><N><F><E><S><S><S><E><W><A><D><L><I><S><S><L><G><K><L><N><K><A><L><Q><S><N><L><R><Y><S><L><L><P><R><R><L><L><I><S><K><R><L><A><Q><C><L><H><P><A><L><P><S><G><V><H><L><K><A><L><E><T><Y><E><I><I><F><K><I><V><G><T><K><W><L><A><K><D><L><F><L><Y><S... | May play a role in regulating membrane trafficking of cargo proteins. Together with ATP9A and MON2, regulates SNX3 retromer-mediated endosomal sorting of WLS away from lysosomal degradation.<BOP> | Q9Y3R5 |
Q11HP8 | RS7_CHESB | 30S ribosomal protein S7 | unclassified Chelativorans | <M><S><R><R><H><R><A><E><K><R><E><I><N><P><D><P><K><F><G><D><T><V><V><T><K><F><M><N><A><I><M><F><E><G><K><K><S><V><A><E><R><I><V><Y><G><A><L><D><Q><V><Q><E><K><T><K><Q><E><P><V><A><V><F><H><Q><A><L><D><N><V><A><P><H><V><E><V><R><S><R><R><V><G><G><A><T><Y><Q><V><P><V><D><V><R><P><E><R><R><Q><A><L><A><I><R><W><L><I><S><A... | One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.<BOP> | Q11HP8 |
Q3J7X9 | HLDD_NITOC | ADP-L-glycero-beta-D-manno-heptose-6-epimerase | Nitrosococcus | <M><I><I><V><T><G><G><A><G><F><I><G><S><N><I><I><K><A><L><N><Q><G><G><R><E><D><I><L><V><V><D><D><L><T><Q><G><E><K><F><S><N><L><I><D><C><E><I><W><D><Y><W><D><K><Q><P><F><L><Q><A><I><K><A><G><E><E><F><P><H><P><V><D><A><F><I><H><Q><G><A><C><S><A><T><T><E><W><N><G><R><Y><M><M><E><N><N><F><Y><Y><S><K><R><L><L><H><Y><C><L><E... | Catalyzes the interconversion between ADP-D-glycero-beta-D-manno-heptose and ADP-L-glycero-beta-D-manno-heptose via an epimerization at carbon 6 of the heptose.<BOP> | Q3J7X9 |
B7LVJ5 | COAD_ESCF3 | Pantetheine-phosphate adenylyltransferase | Escherichia | <M><Q><K><R><A><I><Y><P><G><T><F><D><P><I><T><N><G><H><I><D><I><V><T><R><A><T><Q><M><F><D><H><V><I><L><A><I><A><A><S><P><S><K><K><P><M><F><T><L><E><E><R><V><A><L><A><Q><H><A><T><A><H><L><G><N><V><E><V><V><G><F><S><D><L><M><A><N><F><A><R><N><Q><H><A><T><V><L><I><R><G><L><R><A><V><A><D><F><E><Y><E><M><Q><L><A><H><M><N><R... | Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.<BOP> | B7LVJ5 |
Q49UQ0 | RS6_STAS1 | 30S ribosomal protein S6 | Staphylococcus | <M><R><T><Y><E><V><M><Y><I><I><R><P><N><I><E><E><D><A><K><K><A><V><V><E><R><F><N><G><I><L><A><S><H><G><S><E><V><L><E><A><K><D><W><G><K><R><R><L><A><Y><E><I><N><D><F><S><E><G><Y><Y><N><I><V><R><I><Q><T><A><D><N><E><A><T><D><E><F><Q><R><L><A><K><I><S><D><D><V><I><R><Y><I><V><I><R><E><D><E><D><K><T><R><K> | Binds together with S18 to 16S ribosomal RNA.<BOP> | Q49UQ0 |
Q0I178 | HEM3_HAES1 | Pre-uroporphyrinogen synthase | Histophilus | <M><S><I><N><K><T><L><K><I><A><T><R><Q><S><P><L><A><L><W><Q><A><N><Y><V><K><N><R><L><Q><Q><R><Y><S><H><L><S><V><E><L><V><P><I><I><T><K><G><D><V><I><L><D><T><P><L><A><K><I><G><G><K><G><L><F><V><K><E><L><E><N><A><L><L><N><G><E><A><D><I><A><V><H><S><M><K><D><V><P><M><Q><F><P><K><G><L><E><L><S><V><I><C><P><R><E><D><P><R><D... | Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.<BOP> | Q0I178 |
P62659 | RS18_THET2 | 30S ribosomal protein S18 | Thermus | <M><S><T><K><N><A><K><P><K><K><E><A><Q><R><R><P><S><R><K><A><K><V><K><A><T><L><G><E><F><D><L><R><D><Y><R><N><V><E><V><L><K><R><F><L><S><E><T><G><K><I><L><P><R><R><R><T><G><L><S><A><K><E><Q><R><I><L><A><K><T><I><K><R><A><R><I><L><G><L><L><P><F><T><E><K><L><V><R><K> | Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.<BOP> | P62659 |
Q75I94 | BGL08_ORYSJ | Beta-glucosidase 8 | Oryza sativa | <M><G><C><A><P><A><A><H><Y><L><P><G><G><G><W><R><R><L><L><V><V><V><V><A><L><V><V><L><D><R><A><G><A><R><V><R><A><A><D><D><D><T><G><G><L><S><R><A><A><F><P><K><G><F><V><F><G><T><A><T><S><A><F><Q><V><E><G><M><A><A><S><G><G><R><G><P><S><I><W><D><P><F><V><H><T><P><G><N><I><A><G><N><G><N><A><D><V><T><T><D><E><Y><H><R><Y><K><E... | Hydrolyzes p-nitrophenyl beta-D-glucoside, p-nitrophenyl beta-D-mannoside, p-nitrophenyl beta-D-galactoside, p-nitrophenyl beta-D-xyloside, p-nitrophenyl beta-D-fucoside, p-nitrophenyl beta-L-arabinoside, cello-oligosaccharides, laminari-oligosaccharides, sophorose and gentiobiose.<BOP> | Q75I94 |
Q740T9 | TRHBN_MYCPA | Hemoglobin-like protein HbN | Mycobacterium avium complex (MAC) | <M><K><I><L><A><R><F><R><K><A><E><P><A><S><I><Y><D><R><I><G><G><H><E><A><L><E><V><V><V><E><N><F><Y><V><R><V><L><A><D><E><Q><L><S><G><F><F><T><G><T><N><M><N><R><L><K><G><K><Q><V><E><F><F><A><A><A><L><G><G><P><H><P><Y><T><G><A><P><M><K><Q><V><H><Q><G><R><G><I><T><M><H><H><F><G><L><V><A><G><H><L><A><D><A><L><T><A><A><G><V... | Binds oxygen cooperatively with very high affinity because of a fast combination and a slow dissociation rate.<BOP> | Q740T9 |
Q9V2V6 | PSA1_HALVD | Proteasome subunit alpha 1, N-terminally processed | Haloferax | <M><Q><G><Q><A><Q><Q><Q><A><Y><D><R><G><I><T><I><F><S><P><D><G><R><L><Y><Q><V><E><Y><A><R><E><A><V><K><R><G><T><A><S><I><G><V><R><T><P><E><G><V><V><L><A><A><D><K><R><S><R><S><P><L><M><E><P><T><S><V><E><K><I><H><K><A><D><D><H><I><G><I><A><S><A><G><H><V><A><D><A><R><Q><L><I><D><F><A><R><R><Q><S><Q><V><N><R><L><R><Y><G><E... | Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation. The H.volcanii alpha1-beta proteasome is able to cleave oligopeptides after Phe, Tyr and Trp, poorly after Glu but not after Arg. Thus, displays chymotrypsin-like activity, low caspase-like activity but no... | Q9V2V6 |
B0TM02 | RL14_SHEHH | 50S ribosomal protein L14 | Shewanella | <M><I><Q><M><Q><S><T><L><E><V><A><C><N><S><G><A><R><R><V><Q><C><I><K><V><L><G><G><S><H><R><R><Y><A><G><I><G><D><V><I><K><V><S><V><K><E><A><I><P><R><G><K><A><K><K><G><D><V><Y><N><A><V><V><V><R><T><K><K><G><V><R><R><P><D><G><S><V><I><R><F><D><R><N><A><A><V><L><L><N><A><N><L><A><P><I><G><T><R><I><F><G><P><V><T><R><E><L><R... | Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.<BOP> | B0TM02 |
B3QCH9 | ARGB_RHOPT | NAG kinase | Rhodopseudomonas | <M><T><D><A><P><V><I><S><P><L><D><Q><A><R><I><L><S><E><A><L><P><H><M><Q><R><Y><D><E><E><T><I><V><I><K><Y><G><G><H><A><M><G><A><E><D><T><A><K><A><F><A><R><D><I><V><L><L><E><Q><T><A><V><N><P><V><V><V><H><G><G><G><P><Q><I><A><Q><M><L><K><R><L><G><I><K><S><E><F><A><A><G><L><R><I><T><D><A><A><T><I><E><I><V><E><M><V><L><A><G... | Catalyzes the ATP-dependent phosphorylation of N-acetyl-L-glutamate.<BOP> | B3QCH9 |
Q7WMS0 | FDHD_BORBR | Sulfur carrier protein FdhD | Bordetella | <M><D><R><L><H><T><S><S><A><D><W><P><D><H><L><A><T><Q><V><V><R><V><R><G><G><V><L><Q><A><A><G><Q><S><D><H><V><A><E><E><T><P><V><A><L><E><F><N><G><I><S><H><A><T><M><L><V><T><P><T><H><L><D><D><F><A><L><G><F><A><L><T><E><G><I><V><G><G><M><A><D><V><R><G><V><E><L><E><T><R><C><D><G><I><V><V><Q><V><E><I><A><T><S><C><E><V><R><L... | Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH.<BOP> | Q7WMS0 |
Q1X6Z5 | BDNF_RAMSP | Brain-derived neurotrophic factor | unclassified Ramphotyphlops | <S><C><M><K><A><A><P><M><K><E><V><S><L><R><G><Q><G><N><L><A><Y><P><G><L><R><T><Q><A><N><L><E><N><L><G><G><P><N><D><A><T><R><G><L><T><S><L><A><D><T><F><E><Q><V><I><E><E><L><L><D><E><Q><Q><A><I><Q><P><S><K><E><N><K><D><A><D><L><Y><S><S><R><V><M><L><S><S><Q><V><P><L><E><P><P><L><L><F><L><L><E><E><Y><K><N><Y><L><D><A><A><N... | Promotes the survival of neuronal populations that are all located either in the central nervous system or directly connected to it.<BOP> | Q1X6Z5 |
Q629K1 | TRIQK_HUMAN | Triple repetitive-sequence of QXXK/R protein homolog | Homo | <M><G><R><K><D><A><A><T><I><K><L><P><V><D><Q><Y><R><K><Q><I><G><K><Q><D><Y><K><K><T><K><P><I><L><R><A><T><K><L><K><A><E><A><K><K><T><A><I><G><I><K><E><V><G><L><V><L><A><A><I><L><A><L><L><L><A><F><Y><A><F><F><Y><L><R><L><T><T><D><V><D><P><D><L><D><Q><D><E><D> | May play a role in cell growth and maintenance of cell morphology.<BOP> | Q629K1 |
P51475 | OPSP_CHICK | Pineal gland-specific opsin | Gallus | <M><S><S><N><S><S><Q><A><P><P><N><G><T><P><G><P><F><D><G><P><Q><W><P><Y><Q><A><P><Q><S><T><Y><V><G><V><A><V><L><M><G><T><V><V><A><C><A><S><V><V><N><G><L><V><I><V><V><S><I><C><Y><K><K><L><R><S><P><L><N><Y><I><L><V><N><L><A><V><A><D><L><L><V><T><L><C><G><S><S><V><S><L><S><N><N><I><N><G><F><F><V><F><G><R><R><M><C><E><L><E... | Produces a slow and prolonged phototransduction response consistent with the non-visual function of pineal photoreception.<BOP> | P51475 |
B1ZWG7 | COAD_OPITP | Pantetheine-phosphate adenylyltransferase | Opitutus | <M><R><H><C><I><Y><P><G><T><F><D><P><V><T><Y><G><H><L><D><V><L><A><R><A><V><K><L><F><D><H><V><T><V><A><V><A><E><N><T><P><K><G><P><L><F><T><S><A><Q><R><I><A><M><L><Q><P><N><V><T><R><F><P><N><V><S><V><T><S><F><N><S><L><L><V><E><F><A><M><A><Q><K><A><I><A><V><I><R><G><L><R><A><F><S><D><F><E><F><E><F><H><M><A><L><M><N><R><H... | Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.<BOP> | B1ZWG7 |
B3LTX4 | RRT14_YEAS1 | Regulator of rDNA transcription 14 | Saccharomyces | <M><S><S><S><L><S><Q><T><S><K><Y><Q><A><T><S><V><V><N><G><L><L><S><N><L><L><P><G><V><P><K><I><R><A><N><N><G><K><T><S><V><N><N><G><S><K><A><Q><L><I><D><R><N><L><K><K><R><V><Q><L><Q><N><R><D><V><H><K><I><K><K><K><C><K><L><V><K><K><K><Q><V><K><K><H><K><L><D><K><E><Q><L><E><Q><L><A><K><H><Q><V><L><K><K><H><Q><Q><E><G><T><L... | Involved in ribosome biogenesis, probably through modulation of rDNA transcription.<BOP> | B3LTX4 |
P38604 | ERG7_YEAST | Oxidosqualene--lanosterol cyclase ERG7 | Saccharomyces | <M><T><E><F><Y><S><D><T><I><G><L><P><K><T><D><P><R><L><W><R><L><R><T><D><E><L><G><R><E><S><W><E><Y><L><T><P><Q><Q><A><A><N><D><P><P><S><T><F><T><Q><W><L><L><Q><D><P><K><F><P><Q><P><H><P><E><R><N><K><H><S><P><D><F><S><A><F><D><A><C><H><N><G><A><S><F><F><K><L><L><Q><E><P><D><S><G><I><F><P><C><Q><Y><K><G><P><M><F><M><T><I... | Lanosterol synthase; part of the third module of ergosterol biosynthesis pathway that includes the late steps of the pathway . ERG7 catalyzes the cyclization of (S)-2,3 oxidosqualene to lanosterol, a reaction that forms the sterol core . The third module or late pathway involves the ergosterol synthesis itself through ... | P38604 |
Q6N5R2 | LPXB_RHOPA | Lipid-A-disaccharide synthase | Rhodopseudomonas | <M><S><G><A><A><K><T><G><D><R><V><R><T><V><Y><L><I><A><T><E><E><S><G><D><R><L><G><A><A><L><M><R><E><L><R><A><R><L><G><S><K><V><R><F><A><G><V><G><G><H><C><M><A><G><E><G><L><A><S><L><F><P><I><E><E><L><S><I><I><G><F><A><A><V><V><Q><R><L><P><M><I><L><K><L><I><R><R><A><V><D><A><V><L><T><A><K><P><D><I><L><V><I><I><D><S><P><D... | Condensation of UDP-2,3-diacylglucosamine and 2,3-diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.<BOP> | Q6N5R2 |
Q7WL81 | NADD_BORBR | Nicotinate mononucleotide adenylyltransferase | Bordetella | <M><T><R><I><G><L><L><G><G><S><F><D><P><V><H><V><A><H><I><A><L><A><D><T><A><R><Q><F><L><G><L><D><Q><V><Q><L><I><P><A><A><N><P><W><Q><R><Q><P><L><K><A><S><A><P><H><R><L><R><M><L><E><L><A><I><A><G><H><P><A><L><A><I><N><P><V><E><I><E><R><G><G><A><T><Y><T><A><D><T><V><R><A><L><P><G><G><P><Q><Y><F><W><L><L><G><T><D><Q><L><Q... | Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).<BOP> | Q7WL81 |
Q3SRD1 | TIG_NITWN | PPIase | Nitrobacter | <M><Q><V><N><E><T><L><A><E><G><L><R><H><E><F><Q><V><S><I><P><A><A><E><I><A><A><K><A><D><E><R><L><D><D><L><K><D><K><V><K><I><N><G><F><R><P><G><K><V><P><V><S><H><L><K><K><L><Y><G><R><S><V><M><V><E><T><I><E><D><T><I><R><D><T><N><M><Q><I><V><N><D><R><G><L><K><L><A><G><N><P><K><V><T><M><P><S><E><P><K><E><I><E><D><I><L><A><G... | Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase.<BOP> | Q3SRD1 |
A7HY09 | LPXD_PARL1 | UDP-3-O-acylglucosamine N-acyltransferase | Parvibaculum | <M><A><D><K><R><F><F><E><A><K><E><P><L><S><L><G><E><I><A><G><R><I><G><A><A><L><A><D><A><D><D><G><S><R><I><V><T><G><V><A><P><L><D><T><A><G><S><N><D><L><S><F><L><D><N><P><K><Y><A><E><A><F><Y><A><T><A><A><G><A><C><I><V><H><P><R><F><A><E><R><A><P><D><N><V><A><L><I><L><S><D><Q><P><Y><R><A><Y><A><L><V><A><Q><I><F><H><P><D><E... | Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.<BOP> | A7HY09 |
P87314 | HIR1_SCHPO | Histone transcription regulator 1 homolog | Schizosaccharomyces | <M><K><I><K><K><I><P><W><L><G><H><F><D><D><R><G><H><R><L><S><I><F><S><I><H><I><H><P><D><G><S><R><I><A><T><G><G><L><D><G><T><I><R><I><W><S><T><E><A><I><N><R><E><N><E><N><E><N><E><N><E><D><L><P><K><Q><L><C><C><M><S><T><H><T><G><T><V><T><S><V><R><F><S><P><N><G><Q><Y><L><A><S><G><S><D><D><R><V><V><I><I><W><H><K><E><E><A><I... | Probably required for replication-independent chromatin assembly. Required for transcriptional silencing in the outer repeat (otr) centromeric repeats and the Tf2 long terminal repeat retrotransposons. Repressor of histone gene transcription in G1 arrested cells. Required for repression of htb1 gene expression outside ... | P87314 |
B1LXF3 | ILVC_METRJ | Ketol-acid reductoisomerase type I | Methylobacterium | <M><R><V><Y><Y><D><R><D><A><D><L><N><L><I><K><G><K><K><V><A><I><V><G><Y><G><S><Q><G><H><A><H><A><L><N><L><R><D><S><G><V><K><D><I><V><I><A><L><R><E><G><S><A><T><A><K><K><A><E><H><E><G><F><K><V><L><S><V><A><E><A><A><K><W><A><D><V><V><M><M><L><T><P><D><E><L><Q><G><D><I><Y><R><E><S><L><E><G><N><M><K><Q><G><A><A><L><L><F><A... | Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobu... | B1LXF3 |
P0A5X5 | RS19_MYCBO | 30S ribosomal protein S19 | Mycobacterium tuberculosis complex | <M><P><R><S><L><K><K><G><P><F><V><D><E><H><L><L><K><K><V><D><V><Q><N><E><K><N><T><K><Q><V><I><K><T><W><S><R><R><S><T><I><I><P><D><F><I><G><H><T><F><A><V><H><D><G><R><K><H><V><P><V><F><V><T><E><S><M><V><G><H><K><L><G><E><F><A><P><T><R><T><F><K><G><H><I><K><D><D><R><K><S><K><R><R> | Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.<BOP> | P0A5X5 |
Q9CJ30 | DUT_LACLA | dUTP pyrophosphatase | Lactococcus | <M><K><I><R><G><F><E><V><V><T><K><Y><K><N><A><G><I><N><I><P><K><R><S><T><E><H><S><A><G><Y><D><I><E><A><A><E><T><V><S><F><A><P><G><E><I><K><L><I><P><T><G><L><K><A><Y><M><Q><A><G><E><V><L><Y><M><Y><D><R><S><S><N><P><R><K><K><G><L><V><L><I><N><S><V><G><V><I><D><K><D><Y><Y><N><N><P><D><N><E><G><H><M><F><M><Q><M><R><N><F><T... | This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.<BOP> | Q9CJ30 |
A0LI00 | LEPA_SYNFM | Ribosomal back-translocase LepA | Syntrophobacter | <M><T><K><I><R><N><F><S><I><I><A><H><I><D><H><G><K><S><T><L><A><D><R><L><I><Q><R><A><G><L><V><T><D><R><Q><F><R><D><Q><I><L><D><N><M><D><I><E><R><E><R><G><I><T><I><K><S><Q><T><V><T><L><P><Y><R><S><R><N><G><E><E><V><E><L><N><L><I><D><T><P><G><H><V><D><F><S><Y><E><V><S><R><A><L><A><S><C><E><G><V><L><L><L><V><D><A><S><Q><G... | Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre-t... | A0LI00 |
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